Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AAGAB "FLJ11506, p34" ENSG00000103591 "Alpha and gamma adaptin binding protein" Q6PD74 15 67200667-67255195 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039371, HPA040174" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles, Cytosol" "HPA039371: AB_10805476, HPA040174: AB_10805605" "unprognostic (1.48e-2)" "unprognostic (1.50e-1)" "unprognostic (8.25e-2)" "unprognostic (3.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (2.84e-2)" "unprognostic (4.52e-2)" "unprognostic (9.10e-2)" "unprognostic (5.28e-2)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.36e-4)" "unprognostic (9.88e-2)" "unprognostic (3.05e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (1.53e-1)" 15.1 19.1 10.5 19.2 13.3 19.8 22.5 7.2 14.5 17.9 12.7 27.8 15.8 14.8 25.9 20.5 16.5 18.5 15.8 12.9 15.7 27.4 18.1 15.6 19.9 9.8 11.5 8.0 17.0 35.2 19.0 15.8 11.5 18.8 33.8 22.1 15.4 20.5 32.8 12.9 19.5 21.2 9.5 15.4 23.9 21.9 15.7 29.9 33.0 23.0 25.9 27.5 13.2 12.2 49.7 89.9 63.2 64.8 60.0 49.3 31.1 51.4 74.7 60.6 68.7 66.8 52.9 48.1 51.1 52.9 74.4 98.2 129.9 59.4 62.9 65.0 62.0 46.2 63.2 26.8 66.0 78.8 51.2 48.6 80.6 45.8 94.3 41.0 47.8 59.7 96.5 63.7 60.2 61.3 47.6 32.7 53.1 61.7 31.5 53.1 81.1 57.7 55.9 116.1 89.7 57.3 60.7 44.0 75.7 54.7 71.5 59.2 51.7 54.2 64.5 50.0 73.0 33.7 119.3 69.2 52.7 71.8 55.4 56.4 27.0 28.2 31.3 35.4 36.2 22.0 28.2 29.7 33.2 17.3 23.7 25.0 14.6 42.7 38.1 25.4 37.3 30.2 10.5 13.3 7.2 14.5 12.9 15.7 9.8 11.5 11.5 9.5 15.7 12.2 10.8 3.2 7.7 26.1 19.0 12.0 18.8 19.4 15.9 13.4 17.8 10.3 12.9 4.3 19.0 27.6 27.1 16.3 8.8 33.4 17.6 28.6 14.6 14.5 11.6 12.0 15.7 10.9 45.4 31.2 14.8 14.1 22.4 18.0 10.8 8.2 8.2 12.7 17.0 18.5 33.1 17.3 14.2 15.5 8.4 8.6 7.8 11.6 7.2 30.0 21.3 14.4 16.5 26.2 31.9 25.3 20.9 11.3 15.5 22.9 15.3 19.1 20.5 19.4 13.1 10.5 10.2 43.0 33.8 17.6 13.8 16.6 17.8 25.3 15.7 24.5 ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.7;skin 1: 20.7" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 12.9;Suprabasal keratinocytes: 38.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "hTCEpi: 38.7;SK-BR-3: 18.3;T-47d: 9.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 1.0;hippocampal formation: 1.1" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: AB_2732373" "unprognostic (6.12e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (2.09e-4)" "unprognostic (6.52e-3)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (2.50e-2)" "unprognostic (7.69e-2)" "unprognostic (5.92e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 5.7 0.0 0.1 1.3 0.0 0.3 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.3 0.2 0.2 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 2.8 0.3 3.9 0.1 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 38.7 0.0 2.8 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.4 0.5 0.1 2.7 0.0 18.3 0.0 0.2 9.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 12.9 0.9 6.0 0.0 0.2 1.0 0.5 0.5 0.0 5.1 0.0 0.0 1.1 0.0 3.0 0.0 0.1 2.2 2.6 0.3 0.1 0.0 0.0 1.4 0.0 2.7 0.1 1.5 3.7 0.0 0.5 0.0 0.0 0.4 1.7 2.9 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.6 1.9 0.0 0.7 0.0 1.0 0.0 0.1 3.1 0.2 0.0 0.0 0.2 0.7 0.4 2.2 38.6 3.4 0.0 0.1 0.9 2.7 ABCA5 EST90625 ENSG00000154265 "ATP binding cassette subfamily A member 5" Q8WWZ7 17 69244311-69327244 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 200.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SiHa: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022032, HPA062904" Approved Approved Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 15: RT4 - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "HPA022032: AB_1844427, HPA062904: AB_2732692" "unprognostic (1.24e-2)" "unprognostic (1.49e-2)" "unprognostic (1.62e-3)" "unprognostic (7.17e-2)" "unprognostic (8.05e-4)" "unprognostic (3.05e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-3)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "prognostic favorable (9.97e-5)" "unprognostic (3.60e-2)" "unprognostic (1.09e-3)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (2.55e-1)" "unprognostic (8.52e-2)" 7.6 7.7 4.0 2.9 4.2 6.4 12.2 25.9 9.8 7.9 10.2 9.4 9.5 5.4 7.0 7.0 6.1 4.2 4.7 5.4 9.9 7.0 21.4 3.9 3.4 6.6 3.8 5.7 17.9 11.4 12.5 3.4 7.3 6.0 10.0 27.3 6.7 6.3 33.4 23.6 13.6 3.1 5.3 3.9 8.6 9.1 7.0 5.8 7.4 13.8 3.9 3.5 6.9 6.8 5.1 2.3 1.8 2.8 8.7 6.3 0.6 5.1 5.6 5.3 7.8 0.7 1.8 0.0 2.7 4.5 4.2 7.3 1.2 4.3 5.9 0.1 3.4 0.0 6.0 3.4 11.6 0.0 3.1 6.2 5.2 2.2 6.0 1.1 11.7 1.8 0.0 1.9 0.5 4.3 3.2 0.0 1.8 1.9 3.4 0.4 0.1 0.4 1.0 8.3 10.0 1.5 18.6 8.4 5.0 1.6 8.7 3.2 8.6 6.0 1.7 5.6 1.1 10.3 0.3 0.4 2.4 0.0 5.5 0.3 0.3 2.1 1.3 0.0 1.8 1.1 1.7 1.5 0.2 2.3 0.9 1.4 0.9 1.5 0.0 1.8 1.2 0.6 4.0 4.2 25.9 9.8 5.4 9.9 6.6 3.8 7.3 5.3 7.0 6.8 17.7 19.2 20.3 14.4 12.5 65.4 34.9 35.1 31.3 122.3 33.9 42.8 26.4 30.0 27.8 38.6 116.7 17.3 17.7 126.7 5.9 15.6 18.9 38.6 17.4 18.3 112.7 8.4 143.1 9.8 6.0 33.1 32.6 61.8 14.0 90.3 17.2 94.4 7.4 106.0 184.6 73.7 32.6 3.7 24.4 14.4 63.6 7.0 101.4 20.6 29.9 45.6 11.3 79.9 105.3 9.3 45.6 45.9 23.4 32.1 151.1 9.4 66.0 113.4 92.1 28.7 30.3 200.8 78.1 33.8 53.6 23.7 18.2 80.7 30.4 41.8 ABCB6 "EST45597, MTABC3, umat" ENSG00000115657 "ATP binding cassette subfamily B member 6 (Langereis blood group)" Q9NP58 2 219209772-219218994 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Dyskeratosis congenita, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 14.7;Excitatory neurons: 12.9;Gastric mucus-secreting cells: 5.1;Inhibitory neurons: 10.9;Oligodendrocyte precursor cells: 13.6;Oligodendrocytes: 5.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 65.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046723, HPA058011" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Plasma membrane, Mitochondria, Cytosol" "HPA046723: AB_10960288, HPA058011: AB_2683578" "unprognostic (8.04e-2)" "unprognostic (3.22e-2)" "unprognostic (4.53e-3)" "unprognostic (3.19e-2)" "unprognostic (2.55e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (9.45e-7)" "unprognostic (2.26e-1)" "unprognostic (3.62e-2)" "unprognostic (1.53e-1)" "unprognostic (1.18e-4)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.51e-1)" "unprognostic (9.55e-2)" "unprognostic (7.75e-2)" "unprognostic (2.30e-1)" 10.2 8.7 4.3 3.4 3.9 10.4 7.6 3.2 4.6 7.7 4.4 6.5 6.9 8.4 8.2 11.4 9.6 7.1 8.5 4.0 5.1 5.2 15.9 5.9 1.9 4.4 4.2 12.9 5.7 4.8 6.0 3.1 6.2 8.0 3.3 3.0 6.2 8.6 30.4 6.8 6.3 7.9 4.1 3.9 7.9 18.0 5.7 2.6 10.7 9.8 2.9 14.9 7.9 5.0 0.3 22.9 4.7 28.8 30.8 11.1 27.6 8.5 7.9 9.2 9.2 35.5 5.0 0.3 42.8 8.6 5.0 49.1 0.6 3.6 3.0 15.0 4.7 36.3 24.9 65.8 37.0 0.0 12.0 16.3 4.2 6.2 0.1 13.9 16.3 4.8 31.4 4.4 6.3 12.0 2.3 0.1 7.2 53.6 9.2 12.3 14.3 1.6 5.1 0.4 16.6 17.8 17.6 41.4 18.7 17.4 12.4 0.8 7.5 12.5 0.5 16.9 10.3 11.2 9.6 0.1 14.0 0.4 17.0 0.7 0.4 0.0 0.7 0.4 0.2 1.0 0.5 0.2 0.3 0.8 1.2 0.8 0.0 0.4 0.3 2.3 0.5 1.0 4.3 3.9 3.2 4.6 4.0 5.1 4.4 4.2 6.2 4.1 5.7 5.0 0.2 0.0 0.0 14.7 0.3 0.3 0.0 0.5 1.2 1.0 0.2 0.0 0.2 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.0 0.8 1.2 0.3 0.6 0.4 0.0 1.3 12.9 0.0 0.1 0.7 5.1 0.2 0.0 0.5 0.0 0.4 0.1 0.0 10.9 0.3 0.0 0.3 0.4 1.0 0.3 0.3 0.0 3.7 0.0 0.3 0.0 13.6 5.6 0.3 0.0 0.4 0.5 0.0 0.5 0.2 2.2 0.8 0.0 0.4 0.3 1.0 0.3 2.8 0.3 0.3 0.1 0.4 0.2 0.1 ABCC6 "ARA, EST349056, MLP1, MRP6, PXE, URG7" ENSG00000091262 "ATP binding cassette subfamily C member 6" O95255 16 16149565-16223522 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 31.5;Distal tubular cells: 45.0;Hepatocytes: 77.9;Proximal enterocytes: 33.7;Proximal tubular cells: 151.1" "Group enriched" "Detected in many" 5 "liver cancer: 16.7;renal cancer: 5.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 7 "monocytes: 3.4" "Cell line enriched" "Detected in some" 8 "Hep G2: 68.4" "Not detected" "Not detected" HPA038105 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA038105: AB_2675835" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.09e-1)" "prognostic favorable (3.82e-4)" "unprognostic (6.54e-3)" "unprognostic (3.64e-1)" "unprognostic (9.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-3)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.41e-1)" 5.6 3.6 0.7 0.3 0.7 0.7 3.8 0.7 1.1 1.0 0.8 5.7 13.2 0.3 0.6 0.3 1.5 2.9 2.6 0.7 0.7 27.4 134.2 7.4 0.0 0.8 0.9 1.0 17.2 2.1 0.9 0.2 0.8 2.9 2.8 0.3 12.7 1.0 4.6 0.4 7.9 0.3 0.7 0.7 6.4 0.4 0.8 0.0 5.6 0.1 0.0 0.4 0.7 0.7 0.0 1.5 0.7 0.0 0.0 0.8 1.8 0.0 0.4 1.0 1.6 7.1 2.3 0.0 0.8 0.0 0.2 0.0 0.7 0.1 0.6 0.0 0.7 1.8 0.2 68.4 0.4 0.0 0.0 2.7 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.0 2.3 0.0 0.1 1.0 0.0 0.8 0.1 0.3 8.4 5.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.4 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.7 0.7 0.7 1.1 0.7 0.7 0.8 0.9 0.8 0.7 0.8 0.7 0.3 28.9 31.5 2.9 1.9 0.1 0.5 3.2 0.0 1.0 4.3 3.6 3.3 18.6 8.7 9.2 0.0 0.0 0.0 13.7 45.0 2.2 0.5 4.8 1.0 0.8 3.0 2.7 1.0 7.9 0.0 1.7 13.3 1.0 1.3 1.9 1.8 77.9 1.0 0.0 1.1 10.9 0.0 3.5 0.0 0.7 1.5 1.8 1.8 3.7 3.1 1.5 0.0 1.0 0.4 2.2 8.1 5.7 0.3 2.0 33.7 151.1 25.4 0.6 0.0 0.3 1.2 0.4 0.3 0.2 0.9 0.0 1.4 1.8 11.9 0.7 ACAN "AGC1, CSPG1, CSPGCP, MSK16" ENSG00000157766 Aggrecan P16112 15 88803436-88875353 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.5;seminal vesicle: 3.1" "Group enriched" "Detected in some" 15 "Extravillous trophoblasts: 127.1;Granulosa cells: 132.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "WM-115: 24.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016377, HPA038241, HPA038242" Enhanced "Secreted to extracellular matrix" NA NA 17000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "CAB016377: AB_626650, HPA038241: AB_2675909, HPA038242: AB_2675910" "unprognostic (2.69e-3)" "unprognostic (4.09e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.43e-2)" "unprognostic (2.13e-2)" "unprognostic (1.40e-2)" "unprognostic (1.15e-1)" "unprognostic (7.12e-2)" "unprognostic (8.57e-2)" "unprognostic (2.34e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (7.79e-2)" "unprognostic (1.53e-1)" "unprognostic (7.71e-2)" "unprognostic (7.27e-2)" 1.2 0.2 0.6 0.9 1.0 0.1 0.1 2.2 1.6 0.9 0.1 0.3 0.1 0.4 0.2 0.1 0.2 0.7 0.5 0.7 6.5 0.7 0.1 0.7 0.1 2.1 1.6 0.4 0.2 0.1 0.4 0.2 1.5 0.5 0.3 0.1 0.1 3.1 0.2 0.2 0.1 0.5 1.3 0.2 0.2 1.4 1.5 0.0 0.3 0.0 0.0 0.8 0.7 1.4 0.0 0.0 0.0 0.0 0.8 0.0 4.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 2.2 1.6 0.7 6.5 2.1 1.6 1.5 1.3 1.5 1.4 0.1 0.0 0.0 0.7 0.0 0.4 0.5 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.2 0.3 0.3 0.0 0.0 1.2 0.0 127.1 0.7 0.0 0.4 1.3 132.4 0.0 0.0 2.5 0.0 4.5 0.0 0.0 0.0 0.5 2.1 0.0 0.2 1.8 1.0 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 8.4 2.3 6.3 0.0 0.4 3.6 0.1 1.8 0.0 0.4 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 265.1;testis: 101.9" "Group enriched" "Detected in many" 20 "Early spermatids: 543.6;Late spermatids: 1322.9;Proximal enterocytes: 1172.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC TERT1: 63.3;HUVEC TERT2: 33.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 13.4 4.9 1.7 4.8 8.1 0.1 8.1 0.2 2.5 18.1 0.5 11.2 176.4 8.1 3.5 4.1 6.3 8.2 10.4 1.3 1.0 10.8 1.9 49.0 4.9 1.3 0.9 1.9 6.2 18.7 9.2 11.6 1.3 8.9 6.1 0.4 7.6 23.8 16.1 3.8 265.1 9.6 0.8 2.8 8.3 101.9 2.0 0.8 19.2 10.0 2.1 5.5 3.8 1.1 0.0 0.0 0.0 0.0 2.6 63.3 0.6 2.4 4.7 0.0 0.0 0.9 5.1 1.3 1.8 11.4 0.1 0.0 3.1 0.0 0.0 0.0 1.4 6.6 0.0 0.0 1.4 0.0 0.0 4.2 0.0 0.1 0.0 1.2 33.8 0.0 5.8 0.0 0.1 1.1 0.0 1.4 0.4 11.7 0.7 0.1 0.5 0.9 0.0 0.0 8.2 5.6 0.0 0.0 0.0 1.3 2.9 0.4 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 8.1 0.2 2.5 1.3 1.0 1.3 0.9 1.3 0.8 2.0 1.1 50.0 0.0 3.3 0.0 0.5 1.5 2.6 0.1 1.2 4.0 3.6 1.9 2.1 1.5 0.7 0.0 0.0 0.1 0.3 11.9 0.0 5.9 543.6 10.8 8.0 34.7 18.0 0.0 4.7 0.4 0.1 11.5 2.0 36.3 7.0 24.1 3.6 0.8 4.2 0.0 1.8 39.8 0.0 33.7 3.5 1322.9 4.4 13.6 3.6 4.7 0.0 1.8 0.0 1.0 0.2 0.7 40.9 2.6 0.1 4.2 1172.8 21.7 0.0 1.1 0.0 2.0 4.2 13.5 6.4 0.2 0.1 0.1 2.2 0.3 26.2 2.1 ACP5 "HPAP, TRAP" ENSG00000102575 "Acid phosphatase 5, tartrate resistant" P13686 19 11574660-11579008 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 174.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 426.9;Hofbauer cells: 426.7;Macrophages: 298.2;Proximal tubular cells: 145.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 200.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 41.1;K-562: 30.4;RPMI-8226: 41.4;SK-MEL-30: 127.6;U-138 MG: 102.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002584, HPA057655, HPA059463" Enhanced Uncertain Cytosol "Intracellular and membrane" NA NA 4000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB002584: AB_564039, HPA057655: AB_2683490, HPA059463: AB_2684028" "unprognostic (4.27e-2)" "unprognostic (2.05e-2)" "unprognostic (2.93e-1)" "unprognostic (8.60e-3)" "unprognostic (2.96e-1)" "unprognostic (1.95e-2)" "unprognostic (5.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.13e-2)" "unprognostic (3.80e-1)" "unprognostic (3.66e-3)" "unprognostic (9.09e-2)" "unprognostic (1.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" 9.4 6.0 2.2 42.4 3.9 9.4 25.6 2.5 21.4 34.7 3.0 46.4 31.9 19.2 7.8 23.4 8.6 26.7 5.1 1.9 3.9 74.0 32.5 174.1 87.1 4.1 3.1 20.3 11.9 2.4 1.3 13.3 6.0 19.6 36.4 20.1 14.3 7.0 1.4 24.9 30.2 13.3 4.1 43.5 38.7 4.0 15.7 25.4 3.0 5.0 43.6 33.1 11.3 5.7 10.2 1.1 0.0 0.2 0.5 0.0 41.1 1.1 25.8 0.0 0.1 0.4 0.3 1.4 1.8 9.0 5.9 0.3 0.0 4.5 0.1 12.1 0.8 0.3 0.0 5.0 1.4 0.1 0.6 0.0 4.1 0.4 0.0 0.0 0.0 0.0 30.4 0.2 0.0 2.3 0.9 1.4 0.8 0.3 0.7 0.4 1.8 41.4 0.0 0.4 0.7 1.0 0.0 0.0 127.6 1.1 0.2 0.4 0.9 102.9 1.2 1.8 0.3 0.7 5.7 0.6 23.7 0.1 4.0 0.4 35.3 76.6 15.8 36.1 8.8 200.1 26.0 19.6 7.3 110.9 35.3 20.2 10.4 13.3 36.3 62.5 67.8 36.4 2.2 3.9 2.5 21.4 1.9 3.9 4.1 3.1 6.0 4.1 15.7 5.7 2.2 9.6 7.8 0.0 75.7 10.3 11.0 21.8 25.0 18.3 14.6 18.4 1.4 15.7 5.7 7.3 18.8 33.4 21.2 7.0 9.8 1.8 0.2 0.7 9.1 30.9 3.0 24.5 0.0 11.3 32.7 19.8 10.7 0.9 63.7 0.8 426.9 8.4 426.7 1.7 0.0 4.7 10.2 106.0 68.6 0.7 1.8 298.2 14.2 1.0 79.8 48.5 8.2 0.0 0.1 4.4 20.4 12.0 33.4 14.5 12.7 145.8 2.5 41.4 0.0 0.4 2.8 0.1 0.2 14.6 11.1 26.1 29.5 0.1 6.7 6.1 ACTA2 ACTSA ENSG00000107796 "Actin alpha 2, smooth muscle" P62736 10 88935074-88991339 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 6678.8;seminal vesicle: 5920.3;smooth muscle: 8099.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1007.7;Peritubular cells: 5290.7;Sertoli cells: 3030.6;Smooth muscle cells: 2394.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 390.6;fHDF/TERT166: 641.1;HHSteC: 625.8;HSkMC: 345.1;hTERT-RPE1: 743.4;SuSa: 296.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 101.0" "CAB000002, CAB003761, CAB013531, HPA041264, HPA041271" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "CAB000002: AB_2223500, CAB003761: AB_562031, CAB013531: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.30e-3)" "unprognostic (3.18e-2)" "unprognostic (3.33e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-2)" "unprognostic (1.71e-2)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.44e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (1.37e-8)" "unprognostic (1.87e-3)" "unprognostic (2.30e-1)" "unprognostic (7.91e-2)" "unprognostic (2.09e-3)" 1035.2 241.6 54.0 728.1 61.4 3.9 838.4 52.7 121.1 2000.3 61.4 2755.1 248.9 6678.8 1360.1 1509.9 3104.3 906.1 1069.2 53.4 54.6 312.2 161.8 732.8 173.7 59.0 55.9 798.0 91.4 80.6 60.8 771.3 55.3 2642.8 866.4 8.2 414.7 5920.3 202.1 355.7 701.6 8099.9 54.1 452.1 1427.1 263.9 56.1 56.5 312.0 214.0 48.4 3002.5 1367.0 52.9 3.9 19.0 49.3 102.7 198.1 390.6 9.5 109.8 136.8 11.9 45.4 0.0 8.8 7.2 11.5 641.1 8.6 1.4 1.8 25.4 11.3 60.6 11.3 0.4 5.6 119.3 625.8 0.8 3.2 345.1 44.9 73.9 28.5 743.4 11.3 3.0 0.0 7.1 128.8 10.8 1.0 28.3 2.5 0.2 1.2 1.4 0.2 4.6 27.1 5.0 0.7 7.6 10.2 7.9 1.0 296.8 32.4 1.0 27.9 24.0 4.0 30.2 9.3 21.1 1.6 0.6 29.6 10.2 26.1 28.1 12.3 17.5 17.6 8.7 13.8 6.0 14.1 19.8 10.8 1.8 1.5 10.7 11.1 4.0 14.2 0.4 58.7 10.7 54.0 61.4 52.7 121.1 53.4 54.6 59.0 55.9 55.3 54.1 56.1 52.9 65.4 9.6 6.1 5.5 4.4 43.2 23.4 16.5 22.8 1.1 22.7 1007.7 25.1 2.8 5.2 0.0 6.2 16.3 7.3 1.9 1.9 1.8 11.1 11.1 225.4 41.1 0.0 4.0 3.6 0.9 16.8 316.3 10.7 8.2 5.7 448.9 474.0 4.6 37.7 0.0 1.1 2.7 4.1 5.4 67.6 48.8 141.4 12.6 55.2 61.8 4.2 13.4 4.1 1.0 0.3 2.0 3.0 5290.7 3.7 17.5 3.4 9.5 10.9 1.4 3030.6 72.0 2394.6 4.0 13.8 11.1 40.5 23.7 16.5 36.0 5.7 10.4 ACTB ENSG00000075624 "Actin beta" P60709 7 5526409-5563902 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 22882.9;Pancreatic endocrine cells: 14370.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002621, HPA041264, HPA041271" Supported NA NA 5800000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 3: Monocytes - Immune response regulation" "CAB002621: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (1.66e-1)" "unprognostic (1.15e-1)" "unprognostic (4.20e-2)" "unprognostic (1.15e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.51e-4)" "unprognostic (9.80e-3)" "unprognostic (1.57e-3)" "unprognostic (1.73e-1)" "unprognostic (5.99e-2)" "unprognostic (3.33e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (3.78e-5)" "unprognostic (2.68e-2)" "unprognostic (3.20e-1)" "unprognostic (1.50e-1)" "unprognostic (4.88e-3)" 2558.1 1235.8 2143.2 4250.8 2321.0 3598.4 2009.8 2400.1 2776.1 2274.6 2183.3 6581.2 1659.0 5033.9 1630.3 2928.9 2943.6 1772.1 817.6 2355.6 2315.8 1313.6 1759.9 2876.0 4394.2 2654.8 2338.9 1711.5 761.9 838.5 731.4 1817.2 2569.2 2027.1 2338.4 488.2 1470.2 2943.2 465.1 1541.7 2825.9 5736.8 2457.9 3009.5 2869.7 558.3 2483.4 3278.4 1317.9 524.0 4602.3 3720.8 2223.5 3045.4 7791.1 5198.8 5604.1 4658.2 2321.1 3120.3 6654.3 6049.6 4853.2 6209.7 4619.4 8249.5 4361.9 4522.7 4557.0 9445.4 4904.8 4820.3 3279.5 9453.9 4507.4 5324.6 1668.7 3974.3 4579.6 4520.6 3538.8 4733.2 9853.8 4098.5 2786.7 6863.0 1738.0 4128.6 5073.2 3561.3 2189.7 3513.0 6603.4 7531.9 4055.1 13162.1 6813.7 2468.5 3490.8 5658.6 3351.4 3419.7 5904.6 3175.8 1633.1 2746.9 5754.7 5822.1 2400.3 5088.3 5859.7 5314.8 7975.3 10437.4 7019.9 7000.1 8802.8 1902.3 2442.5 5082.1 5772.0 6622.6 12412.7 14674.1 18104.2 29636.6 10647.1 19648.6 8327.7 5139.6 7639.4 9512.9 19292.5 4844.1 5592.0 7894.3 18040.6 6233.1 22870.8 7122.2 11463.2 37406.8 2143.2 2321.0 2400.1 2776.1 2355.6 2315.8 2654.8 2338.9 2569.2 2457.9 2483.4 3045.4 2775.4 1150.6 680.4 142.4 4118.9 5737.0 9776.6 5792.0 3110.2 146.7 1564.0 2047.2 145.3 1080.9 2763.3 2144.5 85.5 3647.7 3989.3 3419.3 2277.4 6508.8 101.3 1422.1 2344.0 2768.4 1451.5 3170.9 129.3 6365.4 12480.2 2958.5 3136.1 2041.6 1539.9 2372.0 2163.5 2590.6 13977.7 269.2 101.3 2006.7 3694.5 7392.0 11420.0 199.7 1766.7 8486.4 2995.4 259.5 22882.9 1654.4 5237.9 116.1 302.2 14370.0 2899.8 2680.3 3040.4 4764.9 4968.2 2149.2 1453.8 146.7 3287.0 1398.2 5423.9 133.8 381.9 4376.1 4722.2 3257.7 5961.7 1688.9 1966.6 6941.4 ACTC1 "ACTC, CMD1R" ENSG00000159251 "Actin alpha cardiac muscle 1" P68032 15 34790230-34795549 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "heart muscle: 11410.0" "Cell type enriched" "Detected in some" 30 "Cardiomyocytes: 9746.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 1131.8;LHCN-M2: 4544.5;RH-30: 2053.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB037330, HPA041264, HPA041271" Enhanced NA NA 2400000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB037330: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (8.18e-3)" "unprognostic (3.74e-2)" "unprognostic (4.82e-3)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.72e-5)" "unprognostic (3.26e-1)" "unprognostic (2.05e-3)" "unprognostic (2.26e-1)" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (2.10e-3)" "unprognostic (5.68e-4)" "unprognostic (8.79e-2)" "unprognostic (1.65e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (9.32e-4)" 51.1 1.8 1.9 24.7 1.7 0.0 11.9 2.1 2.6 8.6 1.3 4.0 0.8 6.9 1.1 22.8 1.6 11.8 11410.0 1.9 2.8 1.5 0.6 3.9 2.6 2.7 2.8 3.2 12.9 1.0 2.2 8.9 3.0 73.0 3.6 31.6 11.5 538.1 135.2 4.6 0.6 8.8 1.4 1.3 9.3 0.5 4.0 11.3 2.4 195.0 0.2 439.6 16.1 1.5 0.0 0.2 0.1 0.0 0.2 3.3 0.2 2.2 0.7 5.2 1.3 0.0 0.0 0.0 1.3 1131.8 0.2 0.0 0.4 0.0 1.3 0.0 0.0 0.1 23.9 0.0 0.1 1.4 0.0 457.2 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 4544.5 0.0 0.0 0.0 3.8 0.0 0.0 0.0 2053.3 0.0 0.0 0.0 0.1 0.1 4.0 0.0 0.0 31.2 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.7 2.1 2.6 1.9 2.8 2.7 2.8 3.0 1.4 4.0 1.5 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.0 0.0 11.9 0.1 0.0 9746.1 0.0 0.0 0.0 20.9 0.1 0.0 0.0 1.9 0.0 5.0 0.0 0.1 69.2 0.0 0.0 0.2 0.2 4.3 315.2 0.0 0.0 0.0 0.1 0.4 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.2 0.0 63.4 86.5 1.0 0.7 0.0 0.4 0.3 0.1 0.1 0.0 0.0 ACTG1 "ACTG, DFNA20, DFNA26" ENSG00000184009 "Actin gamma 1" P63261 17 81509413-81523847 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, Mental retardation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 9107.1;Exocrine glandular cells: 8305.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041264, HPA041271" Approved NA NA 4900000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (3.95e-2)" "unprognostic (3.38e-1)" "prognostic favorable (2.41e-4)" "unprognostic (2.73e-2)" "unprognostic (1.16e-2)" "unprognostic (1.03e-1)" "unprognostic (1.29e-3)" "unprognostic (2.45e-3)" "unprognostic (3.47e-2)" "unprognostic (3.06e-2)" "unprognostic (4.54e-2)" "unprognostic (9.03e-2)" "unprognostic (1.51e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-2)" "unprognostic (1.25e-1)" "unprognostic (3.40e-3)" 1548.5 950.4 523.3 1325.4 549.3 1130.2 1158.2 582.8 628.6 1634.2 506.2 1258.5 994.5 1629.9 558.1 2422.2 1315.8 1179.5 666.3 548.5 677.3 905.8 762.8 1516.1 1696.9 652.8 592.5 2046.6 1693.4 608.2 824.5 922.4 629.8 723.8 662.3 293.9 1291.3 643.0 358.4 1455.8 1026.3 739.2 589.8 1034.8 1385.5 438.5 611.8 1347.8 1252.2 270.9 1292.7 1540.3 1571.3 709.7 3652.9 4010.4 4601.5 2275.7 813.0 2758.2 1601.3 4193.6 3154.7 3546.5 2675.5 3699.5 1690.3 2114.0 2566.1 4263.6 2867.3 2049.5 1722.7 3395.6 1727.7 3745.8 2549.8 1724.3 1784.6 3515.1 2165.8 1909.2 2003.4 3599.7 1366.0 3586.4 938.0 4516.4 5237.2 1343.4 331.2 2723.2 3288.0 2677.4 6305.5 2235.8 1970.8 2272.7 2122.3 3520.6 1537.3 1716.3 3385.4 2838.3 1234.4 1284.1 4804.4 969.0 5127.0 1530.7 2192.3 1908.9 5402.3 4755.5 1993.3 2802.6 7012.2 908.3 791.7 1505.4 3808.4 1910.5 2940.1 4240.1 1897.3 3013.3 2108.9 2333.9 2026.4 1297.8 1892.2 2024.3 3012.5 939.2 1391.8 1827.7 1532.7 1355.2 2939.2 1616.5 2980.5 5301.8 523.3 549.3 582.8 628.6 548.5 677.3 652.8 592.5 629.8 589.8 611.8 709.7 1602.0 974.4 558.2 107.1 1285.4 5276.1 9107.1 3827.4 2541.1 493.3 1477.5 1943.4 233.6 825.0 1924.3 1140.3 244.0 2002.6 1886.0 2460.0 1058.5 4368.6 293.0 1028.0 1501.0 1664.2 1914.5 567.0 59.0 8305.0 4361.7 1595.3 2440.4 1433.3 588.7 3067.7 1031.6 517.1 3219.5 267.5 65.7 2206.9 1957.2 1426.0 1807.7 258.5 1718.6 1840.3 1398.1 70.3 4004.3 3402.9 1971.2 78.4 111.9 7194.7 2426.5 1363.9 1369.6 3987.9 1673.2 566.6 950.0 571.1 1360.8 873.0 2277.1 756.5 995.7 3085.9 5371.9 2827.2 1823.7 2394.4 2187.5 6279.2 ACTG2 "ACTA3, ACTL3, ACTSG" ENSG00000163017 "Actin gamma 2, smooth muscle" P63267 2 73892314-73919865 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8846.3;seminal vesicle: 6238.4;smooth muscle: 8607.9" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 394.2;Smooth muscle cells: 287.8" "Cancer enhanced" "Detected in all" "prostate cancer: 255.0;stomach cancer: 237.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "T-reg: 8.6" "Lineage enriched" "Detected in single" 17 "T-cells: 8.6" "Cell line enhanced" "Detected in many" "BEWO: 63.8;BJ hTERT+: 53.5;BJ hTERT+ SV40 Large T+: 214.8;HHSteC: 55.1;SuSa: 52.5;U-251 MG: 229.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "midbrain: 11.8;spinal cord: 4.7" "HPA041264, HPA041271" Supported NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (5.79e-3)" "unprognostic (2.25e-1)" "unprognostic (2.36e-2)" "unprognostic (2.91e-1)" "unprognostic (4.56e-3)" "unprognostic (2.50e-1)" "unprognostic (8.05e-2)" "unprognostic (6.53e-2)" "unprognostic (4.48e-2)" "unprognostic (2.93e-1)" "unprognostic (7.23e-2)" "unprognostic (4.75e-2)" "prognostic unfavorable (3.95e-7)" "unprognostic (9.30e-3)" "unprognostic (6.84e-2)" "unprognostic (2.29e-2)" "unprognostic (7.57e-3)" 189.6 37.1 2.8 724.8 3.9 0.0 138.2 2.8 10.0 494.7 4.8 8846.3 392.1 3622.6 124.6 1954.7 857.3 330.4 30.4 2.9 2.9 11.3 10.8 137.5 6.8 3.4 3.1 88.5 8.1 0.9 6.1 96.4 3.1 2250.2 1179.0 0.0 75.1 6238.4 16.3 91.8 1353.8 8607.9 2.9 16.6 2099.7 4.8 3.1 2.8 33.8 6.9 1.2 2914.5 667.3 2.8 0.7 0.3 20.5 0.3 0.0 0.0 63.8 13.5 53.5 214.8 38.6 6.7 0.0 0.3 0.9 0.0 0.4 0.1 36.9 0.0 28.3 0.1 0.0 0.0 2.9 0.5 55.1 0.2 0.6 0.5 0.3 29.0 0.0 1.5 0.0 0.2 0.0 0.0 0.5 0.0 2.9 7.9 0.2 0.0 0.1 0.2 0.4 3.1 0.5 13.6 0.6 2.3 0.3 2.8 1.2 52.5 0.0 0.3 0.0 1.1 2.3 2.5 229.9 0.1 0.3 0.8 0.7 1.0 0.9 0.2 0.5 0.3 0.2 0.3 0.1 0.1 0.8 0.3 0.4 0.1 0.4 0.5 0.1 0.2 0.4 0.1 8.6 2.4 2.8 3.9 2.8 10.0 2.9 2.9 3.4 3.1 3.1 2.9 3.1 2.8 3.5 0.0 0.5 0.0 0.4 4.5 2.7 0.5 0.6 0.0 9.8 394.2 14.6 0.0 0.1 0.0 0.0 7.4 0.7 0.0 0.0 0.0 5.8 2.8 1.5 3.1 0.0 0.0 0.1 0.0 36.8 74.1 0.0 4.8 0.0 1.0 22.9 0.3 5.4 0.0 0.1 0.0 0.0 0.0 10.4 26.6 0.3 1.0 7.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 10.8 0.0 0.4 0.8 0.0 6.6 1.8 287.8 0.2 3.2 0.4 7.7 6.4 1.7 8.4 0.0 3.7 ACVR2B ActR-IIB ENSG00000114739 "Activin A receptor type 2B" Q13705 3 38453890-38493142 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 20.9;NTERA-2: 25.9;SuSa: 14.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025115, HPA040384" Approved NA No "Cluster 54: Non-specific - Microtubule organization" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "CAB025115: , HPA040384: AB_2732484" "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.47e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.32e-2)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.30e-1)" "unprognostic (4.08e-3)" "unprognostic (1.64e-1)" "unprognostic (1.98e-1)" "unprognostic (1.83e-1)" "unprognostic (4.75e-1)" 1.1 2.8 3.2 0.6 3.2 0.2 1.7 5.2 2.8 1.9 1.0 1.5 0.9 1.7 1.7 0.7 1.9 0.6 1.4 2.6 3.0 1.8 2.2 1.3 0.7 2.6 3.2 2.9 2.5 3.3 2.0 2.5 2.6 1.3 1.1 6.5 1.7 1.3 6.0 0.7 1.1 0.9 2.3 1.0 1.5 2.5 2.9 4.1 1.6 2.8 0.6 1.4 1.4 3.6 1.1 1.8 20.9 1.8 0.8 0.5 11.2 0.4 0.7 0.4 0.9 3.1 1.4 0.1 1.6 0.5 0.6 1.3 8.1 1.3 1.1 3.2 5.2 5.6 3.5 4.6 1.0 4.0 2.0 0.8 1.2 0.6 2.3 1.3 1.4 8.0 9.4 1.8 0.4 1.7 6.9 2.5 25.9 1.1 0.9 2.2 7.0 1.4 1.3 2.6 4.9 8.5 0.6 3.2 3.0 14.7 1.7 5.2 1.2 0.7 3.3 0.5 1.8 5.0 7.3 1.2 0.7 3.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.2 3.2 5.2 2.8 2.6 3.0 2.6 3.2 2.6 2.3 2.9 3.6 7.0 6.4 6.1 9.4 0.7 4.0 4.6 2.1 4.0 23.0 5.2 5.0 15.0 2.8 3.6 0.0 22.9 8.5 1.3 3.1 0.0 3.6 11.3 8.7 7.0 7.5 7.2 0.4 12.6 3.8 7.6 3.8 2.6 5.3 1.3 17.9 7.9 8.7 2.6 21.9 17.0 4.1 0.0 2.2 6.4 15.8 11.8 2.4 7.2 5.6 0.7 7.6 0.0 15.1 17.2 3.2 5.3 7.9 1.4 5.2 4.8 3.1 7.1 25.4 0.0 9.7 7.7 11.4 17.9 1.8 4.0 6.2 2.6 7.4 4.4 3.9 ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 96.3" "Cell type enhanced" "Detected in many" "Adipocytes: 107.3;Distal enterocytes: 182.7;Endothelial cells: 84.7;Fibroblasts: 56.0;Hepatic stellate cells: 60.3;Paneth cells: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 19 "classical monocyte: 1.5;myeloid DC: 2.1" "Group enriched" "Detected in many" 19 "dendritic cells: 2.1;monocytes: 1.5" "Cell line enhanced" "Detected in some" "ASC diff: 61.4;ASC TERT1: 42.1;EFO-21: 61.0;HUVEC TERT2: 200.0;TIME: 161.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA007041: AB_1078097" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" "unprognostic (3.79e-2)" "unprognostic (3.61e-2)" "unprognostic (4.98e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.39e-1)" "unprognostic (7.98e-3)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" 49.2 12.1 17.1 20.1 14.5 0.6 38.4 15.5 14.9 35.9 10.5 39.2 10.2 28.1 4.3 11.4 32.7 14.3 38.5 13.3 14.6 29.8 3.3 96.3 15.1 17.8 16.7 4.8 12.0 23.6 6.2 83.8 18.7 17.7 28.4 0.7 11.8 13.3 18.2 18.5 28.5 16.2 14.0 29.2 19.1 1.7 22.0 4.6 29.2 15.7 6.1 25.1 25.6 15.0 0.0 0.7 0.4 0.0 61.4 42.1 0.1 3.0 5.6 0.1 0.3 0.3 0.4 0.1 61.0 24.0 0.2 0.0 0.0 0.0 0.1 0.1 2.1 1.4 0.0 0.0 9.0 0.0 1.3 16.8 0.1 0.4 0.0 0.0 200.0 0.0 0.2 0.1 1.1 0.5 0.0 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 0.1 0.4 0.0 4.1 161.2 0.0 0.4 0.7 0.0 0.0 0.1 0.2 0.3 0.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 17.1 14.5 15.5 14.9 13.3 14.6 17.8 16.7 18.7 14.0 22.0 15.0 107.3 3.2 7.9 0.0 0.6 5.2 0.3 0.0 0.6 0.4 1.0 1.3 4.0 0.0 1.3 0.0 0.0 0.6 0.3 182.7 0.0 4.0 0.0 1.4 19.9 84.7 5.4 0.0 0.1 1.4 36.9 56.0 0.5 0.7 0.0 0.0 60.3 0.1 12.0 0.0 0.0 26.4 0.0 30.9 12.4 1.2 11.8 7.8 5.4 25.3 9.9 2.0 0.0 1.0 0.1 0.0 74.7 3.4 0.1 0.6 4.5 0.0 2.8 0.4 39.5 32.9 18.2 0.1 0.8 0.6 5.4 2.6 1.2 0.6 49.3 1.0 ADAMTS10 ADAM-TS10 ENSG00000142303 "ADAM metallopeptidase with thrombospondin type 1 motif 10" Q9H324 19 8580240-8610735 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 18.3;Excitatory neurons: 21.4;Inhibitory neurons: 19.9;Microglial cells: 30.9;Skeletal myocytes: 15.9;Smooth muscle cells: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 7.2;hTERT-RPE1: 7.5;NB-4: 37.0;REH: 9.8" "Region enriched" "Detected in many" 5 "cerebellum: 8.8" "Low region specificity" "Detected in all" HPA040223 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA040223: AB_10795376" "unprognostic (2.60e-1)" "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (1.14e-1)" "unprognostic (8.16e-2)" "unprognostic (1.91e-4)" "unprognostic (4.98e-3)" "unprognostic (4.06e-2)" "unprognostic (2.24e-2)" "unprognostic (6.52e-2)" "unprognostic (2.47e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (6.86e-3)" "unprognostic (1.71e-1)" "unprognostic (2.33e-1)" "unprognostic (4.12e-2)" 15.9 8.2 7.1 2.3 7.3 1.8 9.5 5.0 11.9 13.0 5.8 7.3 0.8 12.7 0.7 4.1 10.2 1.9 8.5 7.6 8.7 6.9 6.3 8.2 3.2 7.1 6.8 8.3 7.8 0.8 4.1 1.7 6.7 8.4 0.5 0.4 4.1 1.5 2.8 8.8 6.3 1.5 6.0 5.4 3.8 2.4 8.1 1.4 6.2 0.8 1.3 5.7 8.7 6.5 0.0 4.6 2.5 0.0 0.4 0.3 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.2 1.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.0 7.2 0.0 0.3 0.0 0.1 1.8 0.0 0.0 0.0 7.5 0.1 0.3 0.1 0.0 0.0 0.0 0.3 37.0 1.5 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 1.2 0.1 0.4 2.0 3.1 4.4 2.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 7.3 5.0 11.9 7.6 8.7 7.1 6.8 6.7 6.0 8.1 6.5 5.6 0.0 0.0 18.3 0.3 1.7 0.6 0.1 0.0 1.5 1.2 1.5 1.3 5.7 0.1 0.0 0.0 0.1 6.9 0.0 0.0 8.8 5.1 0.4 7.4 5.8 0.0 1.3 21.4 0.5 0.0 6.4 1.1 0.4 0.0 1.8 6.8 2.0 0.9 0.0 19.9 0.3 0.0 2.7 6.0 2.4 7.5 3.3 0.0 30.9 0.6 0.8 11.3 9.5 1.2 0.9 0.0 6.0 1.3 0.2 0.0 0.1 0.0 0.2 6.6 15.9 15.0 0.1 0.4 0.1 0.9 0.4 3.2 0.6 0.1 0.3 ADAMTS17 "FLJ16363, FLJ32769" ENSG00000140470 "ADAM metallopeptidase with thrombospondin type 1 motif 17" Q8TE56 15 99971437-100342005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Deafness, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.7" "Group enriched" "Detected in many" 8 "Astrocytes: 116.9;Early spermatids: 108.4;Inhibitory neurons: 275.7;Late spermatids: 91.0;Oligodendrocyte precursor cells: 337.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEK 293: 6.4;JURKAT: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062487 Approved Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA062487: AB_2684780" "unprognostic (7.73e-2)" "unprognostic (2.38e-2)" "unprognostic (1.79e-2)" "unprognostic (9.03e-3)" "unprognostic (2.56e-1)" "unprognostic (9.90e-3)" "unprognostic (5.78e-2)" "unprognostic (1.18e-3)" "unprognostic (5.03e-3)" "unprognostic (4.70e-2)" "unprognostic (2.93e-1)" "unprognostic (1.27e-1)" "unprognostic (3.35e-2)" "unprognostic (8.48e-2)" "unprognostic (1.21e-1)" "unprognostic (7.43e-3)" "unprognostic (6.43e-2)" 0.8 1.2 1.6 0.5 1.1 0.6 0.6 0.3 2.7 1.4 6.0 0.9 0.6 1.2 0.6 2.1 1.8 0.3 1.3 1.3 0.6 1.1 7.5 1.5 0.5 1.2 0.7 1.7 5.0 0.2 1.2 0.5 0.8 1.0 0.4 0.7 2.6 0.5 5.6 2.2 1.2 0.5 0.7 0.9 1.0 2.7 1.0 10.7 0.7 0.1 0.5 1.6 1.4 1.1 0.0 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 1.2 0.3 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.7 2.0 0.5 0.2 0.9 1.0 0.0 0.3 2.3 0.0 0.2 1.7 0.2 0.2 2.2 2.7 0.4 0.0 0.2 0.3 0.0 0.6 0.6 0.0 0.2 0.0 0.0 0.0 0.4 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.1 0.3 2.7 1.3 0.6 1.2 0.7 0.8 0.7 1.0 1.1 0.7 0.0 0.0 116.9 0.3 1.0 0.9 0.1 3.4 0.8 1.5 1.3 4.3 1.5 0.9 0.0 0.0 0.1 2.6 0.4 1.9 0.1 108.4 1.2 2.8 0.9 0.0 0.0 8.2 0.9 0.0 1.6 5.1 1.8 0.0 0.1 0.4 4.4 8.2 21.9 275.7 0.7 0.0 0.6 0.3 91.0 2.1 0.4 0.0 22.5 0.0 1.3 1.0 337.3 9.5 0.3 0.2 0.0 0.8 1.6 0.5 0.1 0.0 0.7 0.0 3.2 0.9 1.7 1.9 2.1 0.6 0.1 3.7 2.5 0.4 0.9 ADAMTS18 ADAMTS21 ENSG00000140873 "ADAM metallopeptidase with thrombospondin type 1 motif 18" Q8TE60 16 77247813-77435034 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.0;placenta: 20.6" "Cell type enhanced" "Detected in some" "Adipocytes: 36.8;Granulosa cells: 15.0;Muller glia cells: 13.7;Oligodendrocytes: 16.9;Rod photoreceptor cells: 7.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 11.6;HUVEC TERT2: 8.0;SuSa: 10.6;TIME: 2.5;U-87 MG: 4.8" "Region enriched" "Detected in single" 5 "cerebellum: 3.3" "Low region specificity" "Detected in all" HPA044326 Uncertain Approved "Midbody,Mitotic spindle" "Secreted to extracellular matrix" Yes NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Midbody, Mitotic spindle" "HPA044326: AB_10961006" "unprognostic (1.10e-2)" "unprognostic (2.78e-1)" "unprognostic (1.38e-1)" "unprognostic (2.50e-1)" "unprognostic (8.13e-2)" "unprognostic (2.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.98e-1)" "unprognostic (4.11e-2)" "unprognostic (2.20e-2)" "unprognostic (8.17e-4)" "unprognostic (1.77e-5)" "unprognostic (2.17e-1)" "unprognostic (3.41e-1)" "unprognostic (2.47e-4)" 3.1 0.1 1.3 0.3 3.0 0.0 2.9 11.0 2.5 1.2 0.5 0.0 0.1 0.8 0.0 0.1 0.2 0.6 0.0 1.8 2.7 0.2 0.0 0.1 0.1 4.3 2.4 0.1 0.3 0.0 0.8 20.6 3.7 0.4 0.0 2.0 1.3 0.1 0.6 0.1 0.0 0.6 1.7 0.0 0.0 0.2 2.4 0.9 0.0 0.0 0.0 0.9 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.6 0.0 0.5 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.0 11.0 2.5 1.8 2.7 4.3 2.4 3.7 1.7 2.4 5.9 36.8 0.0 0.0 4.6 0.1 0.1 0.1 0.0 0.0 1.8 1.5 4.3 0.6 0.0 0.0 1.8 2.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.3 0.0 15.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 13.7 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.1 0.2 0.6 0.0 0.1 0.3 0.0 0.1 0.0 0.0 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 32.2;Excitatory neurons: 17.9;Fibroblasts: 30.7;Hepatic stellate cells: 17.2;Kupffer cells: 71.4;Sertoli cells: 26.3;Smooth muscle cells: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.0;ASC TERT1: 35.8;BJ: 31.4;fHDF/TERT166: 39.3;HHSteC: 115.5;HSkMC: 94.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 2000000 "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 36.9 10.9 0.8 2.4 4.2 0.3 22.7 0.9 3.5 20.6 0.9 10.5 1.4 21.7 0.5 5.5 15.5 6.1 22.3 0.5 0.9 7.5 15.8 29.6 1.8 4.5 3.3 12.1 5.8 0.4 15.1 9.7 4.2 9.0 1.4 0.2 5.3 1.8 2.9 9.4 11.6 9.1 0.2 38.4 9.3 3.9 2.5 0.4 6.8 0.8 0.6 15.0 16.7 2.2 0.0 0.0 0.1 0.7 36.0 35.8 0.0 31.4 5.4 11.5 12.4 0.1 0.0 0.0 0.2 39.3 0.7 0.1 1.8 0.0 5.1 0.0 1.5 0.0 0.1 2.3 115.5 0.0 0.0 94.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.1 0.8 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.9 1.2 0.1 0.0 0.4 1.9 0.0 10.7 0.0 19.1 3.0 24.5 0.0 0.3 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.8 4.2 0.9 3.5 0.5 0.9 4.5 3.3 4.2 0.2 2.5 2.2 3.3 0.0 1.1 1.6 0.1 2.2 0.4 0.0 2.2 0.3 0.2 5.2 1.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.3 0.9 32.2 1.4 0.0 0.0 17.9 0.0 0.3 30.7 0.0 0.8 1.3 6.5 17.2 0.5 5.1 0.0 8.5 0.0 0.0 71.4 4.4 3.4 5.0 10.4 0.0 4.7 0.3 0.1 0.0 3.0 2.4 0.5 0.0 12.8 0.1 0.4 0.0 0.2 0.0 0.0 26.3 4.7 20.4 2.1 4.8 0.2 2.7 0.0 0.4 0.6 0.0 0.1 ADAMTS3 "ADAMTS-4, KIAA0366" ENSG00000156140 "ADAM metallopeptidase with thrombospondin type 1 motif 3" O15072 4 72280969-72569221 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Excitatory neurons: 50.2;Leydig cells: 19.9;Rod photoreceptor cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.2;AN3-CA: 7.8;HEL: 14.1;K-562: 12.3;SH-SY5Y: 7.0;U-2 OS: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021368, HPA021369" Uncertain Approved "Intermediate filaments" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Intermediate filaments" "HPA021368: AB_2670681, HPA021369: AB_2670682" "unprognostic (1.93e-1)" "unprognostic (3.47e-3)" "unprognostic (1.41e-1)" "unprognostic (1.05e-3)" "unprognostic (6.11e-2)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (1.60e-3)" "unprognostic (5.92e-4)" "unprognostic (3.11e-2)" "unprognostic (1.93e-1)" "unprognostic (2.60e-1)" "unprognostic (8.63e-3)" "unprognostic (1.65e-3)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" "unprognostic (1.50e-4)" 2.3 0.8 0.5 1.0 2.5 0.8 3.2 0.0 1.5 0.4 0.1 0.3 0.1 1.9 1.7 0.2 2.9 0.6 0.9 1.5 0.6 0.9 0.2 1.1 0.8 0.0 0.2 2.0 0.3 2.7 0.2 0.7 0.1 0.7 0.3 8.4 0.4 1.1 0.2 0.4 0.2 1.7 0.0 0.7 0.5 1.9 0.1 0.6 1.2 0.3 0.3 1.3 0.4 0.4 0.0 0.0 13.2 7.8 0.1 0.3 0.1 0.7 2.1 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.8 0.0 1.8 0.0 1.8 14.1 0.9 0.0 0.2 0.0 0.0 1.7 0.1 0.6 0.1 3.3 0.0 0.0 12.3 0.0 0.0 0.0 1.3 0.0 2.2 0.0 4.0 0.0 2.6 0.0 4.6 0.0 0.5 7.0 0.0 0.6 0.2 1.4 0.1 0.2 0.1 5.6 8.5 0.0 0.7 0.0 0.0 0.0 1.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.5 0.0 1.5 1.5 0.6 0.0 0.2 0.1 0.0 0.1 0.4 1.8 0.0 3.4 7.5 0.0 0.5 0.9 0.0 0.0 0.9 0.8 3.2 1.2 1.5 1.3 1.8 14.6 0.0 0.0 0.0 0.0 0.0 4.1 2.2 5.1 3.7 0.0 2.5 50.2 0.0 0.3 3.3 0.0 0.7 1.3 1.9 3.9 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.7 1.9 19.9 0.3 0.0 1.0 0.0 1.8 0.0 7.1 1.3 0.0 0.0 4.5 0.0 1.1 0.0 0.3 0.5 12.9 0.0 0.3 1.2 1.2 0.8 0.3 0.0 0.0 0.0 2.8 0.0 0.1 ADAMTSL2 KIAA0605 ENSG00000197859 "ADAMTS like 2" Q86TH1 9 133532164-133575519 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.2;liver: 35.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Endothelial cells: 5.7;Fibroblasts: 8.5;Microglial cells: 12.2;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 7.4;RPMI-8226: 10.1;SH-SY5Y: 30.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045634, HPA053812" Approved Approved Vesicles "Secreted in other tissues" NA NA 170000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA045634: AB_2679399, HPA053812: AB_2682271" "unprognostic (5.10e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.35e-2)" "unprognostic (1.07e-1)" "unprognostic (5.50e-2)" "unprognostic (6.78e-3)" "unprognostic (1.31e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.17e-2)" "unprognostic (7.37e-2)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" 3.7 28.5 6.8 1.0 7.3 0.1 1.5 12.0 10.1 2.3 1.4 2.7 1.4 3.1 3.1 1.8 3.1 2.5 73.2 5.8 7.9 25.9 35.8 23.2 3.4 19.3 11.1 4.9 7.1 1.2 15.9 1.5 20.8 8.4 0.3 0.3 3.4 2.2 4.3 0.8 3.2 0.9 8.5 6.4 2.3 3.1 9.3 0.6 12.1 0.5 0.6 5.3 1.6 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.6 0.5 0.0 1.1 0.7 10.1 0.0 0.0 1.4 30.1 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 7.3 12.0 10.1 5.8 7.9 19.3 11.1 20.8 8.5 9.3 7.6 1.4 0.0 0.5 4.9 0.1 0.1 0.1 0.0 0.0 4.2 0.0 0.1 2.3 0.0 0.0 1.8 0.0 0.1 0.0 1.4 5.9 0.2 0.1 0.1 0.1 5.7 5.3 0.0 5.0 0.0 0.1 8.5 0.0 0.0 0.0 0.1 4.6 0.9 0.3 0.0 3.8 0.4 0.0 0.3 0.8 1.1 4.7 0.6 0.0 12.2 0.0 0.4 0.0 2.5 4.0 0.2 0.5 3.0 0.0 0.2 0.0 0.7 0.0 0.2 6.6 1.1 1.6 0.1 0.8 0.4 0.3 0.0 0.6 0.7 1.1 0.2 ADAMTSL4 "DKFZP434K1772, TSRC1" ENSG00000143382 "ADAMTS like 4" Q6UY14 1 150549369-150560937 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 146.7;Endometrial stromal cells: 36.9;Extravillous trophoblasts: 46.4;Fibroblasts: 34.5;Hofbauer cells: 34.0;Syncytiotrophoblasts: 99.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 11.1" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 92.0;BEWO: 200.3;HSkMC: 43.8;K-562: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA006279 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA006279: AB_1078102" "unprognostic (2.00e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (8.09e-4)" "prognostic unfavorable (2.43e-4)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.56e-2)" "unprognostic (1.68e-2)" "unprognostic (1.28e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.90e-1)" "unprognostic (5.23e-2)" "unprognostic (1.44e-2)" "unprognostic (7.40e-3)" 32.0 5.1 1.1 14.9 1.0 4.2 24.7 0.8 11.1 22.9 7.9 19.3 3.6 20.0 1.6 33.3 29.2 7.7 22.3 0.8 1.4 6.4 17.3 26.1 1.8 4.4 2.8 17.1 3.0 0.5 3.0 62.9 2.9 9.0 3.8 0.6 11.8 3.4 37.7 11.8 13.7 11.4 1.2 5.4 17.2 2.4 3.6 0.8 6.1 47.9 1.2 32.8 23.3 1.5 22.0 0.6 0.3 3.9 19.1 92.0 200.3 20.8 18.0 12.1 7.0 1.8 8.5 0.2 4.3 14.4 0.2 11.0 0.8 3.2 4.9 1.7 0.4 6.2 2.6 8.9 15.3 0.3 3.0 43.8 0.9 3.0 6.8 10.3 0.1 0.0 67.7 0.7 2.2 0.5 0.0 1.1 3.5 0.6 0.7 0.0 0.0 0.1 2.1 0.8 0.1 0.6 6.7 15.9 0.1 10.0 4.5 11.5 3.8 0.7 5.5 8.6 0.3 1.9 0.6 4.5 0.8 4.0 0.5 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.3 1.1 1.0 0.8 11.1 0.8 1.4 4.4 2.8 2.9 1.2 3.6 1.5 2.8 0.0 1.5 1.0 0.5 2.4 2.3 0.2 0.6 1.7 1.3 1.8 2.2 10.0 0.6 0.0 0.0 146.7 1.0 0.2 0.0 1.7 0.6 2.6 36.9 5.3 0.0 0.0 0.3 0.6 46.4 34.5 0.0 5.4 2.5 0.9 1.8 10.6 34.0 0.0 0.1 0.2 0.0 24.0 12.5 0.7 30.1 20.0 3.6 0.0 23.1 1.4 1.0 0.0 0.0 12.3 0.1 3.4 3.2 2.2 0.0 0.2 0.9 2.2 0.0 14.3 3.8 0.1 1.6 5.5 2.8 99.5 1.7 0.5 0.3 2.5 ADCY6 AC6 ENSG00000174233 "Adenylate cyclase 6" O43306 12 48766194-48789089 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 68.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018365 Approved Approved "Golgi apparatus" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "CAB018365: AB_2257941" "unprognostic (1.18e-2)" "unprognostic (2.20e-2)" "unprognostic (6.89e-2)" "unprognostic (1.31e-1)" "unprognostic (3.84e-2)" "unprognostic (3.68e-2)" "prognostic unfavorable (8.23e-4)" "unprognostic (1.55e-1)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.64e-2)" "unprognostic (5.06e-3)" "unprognostic (5.10e-3)" "unprognostic (1.09e-1)" "unprognostic (3.09e-1)" "unprognostic (2.48e-2)" 43.2 15.0 8.9 6.1 7.9 1.3 23.7 5.0 9.2 19.3 10.3 26.3 18.7 20.7 19.0 10.3 17.1 13.9 57.2 8.0 11.2 21.1 9.6 13.5 3.9 5.5 5.4 22.3 22.3 20.7 14.6 14.5 6.6 16.3 20.3 5.7 33.5 16.5 12.1 15.3 21.4 13.6 1.9 4.8 25.1 4.0 14.4 2.8 17.9 12.7 3.2 12.3 12.8 6.4 14.0 25.9 30.2 18.9 32.0 15.9 32.0 16.7 17.1 19.8 13.8 45.7 45.3 0.0 37.2 15.3 8.2 10.9 9.2 11.6 7.9 0.1 13.4 12.5 37.8 8.4 17.6 0.0 10.1 20.0 13.6 17.1 6.5 37.9 18.7 0.8 1.7 4.5 15.6 23.1 0.0 0.5 10.3 21.6 12.3 4.6 11.4 7.7 23.4 41.5 4.5 18.4 17.2 68.0 15.2 13.3 53.3 3.5 21.1 18.3 13.1 9.7 7.4 7.0 3.7 0.4 16.9 0.0 8.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.9 7.9 5.0 9.2 8.0 11.2 5.5 5.4 6.6 1.9 14.4 6.4 11.6 0.0 6.4 18.3 0.6 2.7 3.3 7.5 4.0 10.1 22.7 15.0 8.2 7.2 9.8 18.4 20.9 7.4 0.4 38.8 0.0 5.8 0.8 6.8 8.0 8.1 8.4 0.0 17.5 4.0 2.7 7.6 14.3 11.3 1.3 14.6 5.0 7.7 2.5 10.1 18.8 24.9 8.2 0.6 2.8 1.1 11.5 0.7 7.2 7.5 0.6 3.4 0.0 15.1 7.0 9.5 30.3 9.4 0.3 6.3 26.0 2.8 5.8 9.3 19.7 9.5 26.6 1.9 1.7 3.6 2.0 5.1 0.8 13.9 23.7 9.3 ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 216.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 222.5;Exocrine glandular cells: 170.7;NK-cells: 208.1;Syncytiotrophoblasts: 186.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.3" "Lineage enriched" "Detected in many" 5 "T-cells: 160.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 218.4;SK-BR-3: 277.7;SK-MEL-30: 297.8;TIME: 241.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" NA NA 32000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA046065: AB_2679521" "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favorable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" 50.9 13.2 79.6 12.7 67.7 19.6 50.5 46.9 115.2 36.3 0.0 36.7 26.1 19.7 84.2 46.7 52.2 69.6 36.8 68.7 71.5 158.9 4.2 37.3 5.2 64.6 76.2 5.3 59.8 28.4 17.7 101.3 73.9 31.7 33.4 6.6 92.2 57.5 15.7 87.5 19.3 19.8 54.8 12.3 47.9 45.4 92.5 28.9 216.3 16.9 15.6 37.1 37.8 51.6 41.8 47.1 12.0 0.6 0.0 0.1 127.7 8.5 3.9 14.4 2.6 34.7 218.4 0.2 110.5 8.2 196.1 149.1 0.0 103.4 5.1 1.6 0.0 5.1 56.0 39.3 0.3 0.4 2.1 2.4 143.8 24.5 10.2 15.8 118.1 1.0 0.1 1.2 3.2 51.4 107.3 0.8 1.7 143.3 42.6 3.8 1.4 30.8 209.4 134.9 38.2 1.2 2.0 277.7 297.8 8.4 123.8 0.8 241.4 25.6 38.0 1.5 96.2 0.2 2.1 0.6 200.5 0.7 62.9 2.9 0.8 0.2 160.3 0.5 1.9 0.3 10.5 62.6 0.2 0.1 5.3 45.2 3.3 30.6 0.7 0.3 0.2 37.1 79.6 67.7 46.9 115.2 68.7 71.5 64.6 76.2 73.9 54.8 92.5 51.6 107.7 9.6 11.9 113.9 3.7 0.0 24.1 0.0 11.4 0.9 29.6 27.2 4.3 15.7 21.7 79.1 0.0 222.5 120.4 17.7 27.4 33.9 74.0 24.6 4.3 53.9 20.6 17.7 3.5 170.7 25.1 4.7 29.0 45.2 5.1 88.2 30.0 0.5 22.8 0.0 4.9 23.2 0.0 3.5 0.0 31.3 3.1 6.1 0.0 41.2 1.1 4.8 208.1 85.5 1.3 101.1 12.3 0.0 19.1 15.2 5.6 132.6 16.8 0.5 0.0 1.6 7.1 2.7 0.9 23.0 0.0 186.5 35.1 0.4 24.6 19.5 ADGRG2 "EDDM6, GPR64, HE6, TM7LN2" ENSG00000173698 "Adhesion G protein-coupled receptor G2" Q8IZP9 X 18989307-19122637 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 1227.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 7.2;Endometrial stromal cells: 5.4;Fibroblasts: 5.3;Gastric mucus-secreting cells: 9.2;Oligodendrocyte precursor cells: 10.1;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.0;BEWO: 7.3;HeLa: 5.9;NTERA-2: 6.4;RPMI-8226: 4.5;SH-SY5Y: 6.6;U-2197: 14.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA001478, HPA050029" Enhanced Approved "Plasma membrane,Cytosol" NA NA 22000000 "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA001478: AB_1078923, HPA050029: AB_2680996" "unprognostic (3.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.40e-1)" "unprognostic (2.55e-2)" "unprognostic (1.58e-1)" "unprognostic (4.43e-3)" "unprognostic (2.63e-4)" "unprognostic (2.66e-1)" "unprognostic (1.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-7)" "unprognostic (6.37e-2)" "unprognostic (3.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.35e-1)" 3.9 0.3 0.1 0.9 0.1 0.0 2.0 0.0 1.1 1.0 0.0 0.5 0.5 1.0 1227.7 0.5 16.5 1.6 1.3 0.8 0.7 0.4 0.7 1.3 5.0 0.4 1.5 0.2 1.2 163.4 1.1 0.5 0.6 2.1 0.4 0.9 8.5 3.6 0.2 0.4 1.1 0.4 0.1 2.4 9.0 1.9 0.3 6.6 1.6 1.1 3.7 0.8 1.0 0.2 0.2 6.0 0.0 0.0 0.1 0.9 7.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.4 0.0 5.9 0.2 0.8 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 2.2 6.4 0.0 2.0 0.0 0.0 4.5 0.0 1.2 2.2 6.6 1.5 0.1 0.0 1.1 0.1 0.1 0.1 0.2 0.4 14.6 2.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.8 0.7 0.4 1.5 0.6 0.1 0.3 0.2 0.6 0.0 0.0 3.6 0.1 0.0 0.1 0.0 0.0 0.6 1.2 1.1 1.0 7.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.1 1.1 5.4 0.6 0.0 0.0 4.4 0.2 0.3 5.3 9.2 3.2 0.0 0.2 1.4 0.4 0.0 3.3 5.0 0.1 0.0 0.0 0.0 0.2 1.2 0.1 0.0 4.7 0.0 4.8 0.0 10.1 7.0 3.1 0.0 1.5 0.0 3.4 0.0 0.1 2.2 0.7 0.0 1.6 0.6 0.1 1.4 0.1 0.0 0.0 0.3 0.3 0.0 0.3 ADGRG6 "FLJ14937, GPR126" ENSG00000112414 "Adhesion G protein-coupled receptor G6" Q86SQ4 6 142301854-142446266 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 71.9;placenta: 47.4" "Cell type enhanced" "Detected in many" "Endothelial cells: 41.7;Hepatocytes: 143.8;Kupffer cells: 40.5;Pancreatic endocrine cells: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 88.6;Hep G2: 84.8;hTERT-HME1: 81.5;HUVEC TERT2: 161.4;MCF7: 155.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017346 Approved NA NA 110000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA017346: AB_1849260" "unprognostic (1.04e-2)" "unprognostic (2.72e-2)" "unprognostic (7.37e-2)" "unprognostic (3.00e-2)" "unprognostic (8.64e-4)" "unprognostic (1.67e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.78e-5)" "unprognostic (4.46e-1)" "unprognostic (6.49e-2)" "unprognostic (2.15e-1)" "unprognostic (1.36e-2)" "unprognostic (2.97e-2)" "unprognostic (4.59e-2)" 5.8 2.8 2.6 4.1 2.3 0.4 5.2 1.6 1.9 3.0 1.9 6.2 17.5 1.1 1.3 11.6 5.2 8.3 4.0 1.8 1.7 7.2 71.9 15.2 1.7 2.4 2.9 1.4 3.2 1.3 0.3 47.4 2.2 3.2 6.4 0.1 9.0 6.5 0.5 14.5 10.2 2.2 2.5 7.5 12.3 2.1 4.6 4.6 1.6 1.2 4.0 15.1 5.6 1.9 17.0 88.6 1.9 9.4 0.5 0.0 0.2 23.1 4.3 17.2 10.7 71.3 51.0 0.0 20.3 13.4 4.9 41.3 2.6 22.1 28.3 0.0 6.8 3.6 14.5 84.8 16.7 14.6 0.0 0.1 34.9 0.4 81.5 10.0 161.4 0.4 0.6 0.1 6.9 155.6 0.3 0.0 0.7 6.2 20.0 0.0 7.7 17.7 9.0 37.9 0.1 0.1 6.8 30.8 14.5 14.1 16.7 0.3 5.6 0.1 7.6 7.7 11.5 0.0 0.1 0.0 0.1 0.1 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.3 1.6 1.9 1.8 1.7 2.4 2.9 2.2 2.5 4.6 1.9 5.1 6.4 5.9 0.0 0.3 0.0 21.9 0.0 18.8 0.0 5.3 2.7 1.9 24.3 8.1 9.2 0.0 5.3 0.0 0.6 0.0 13.2 0.1 0.1 0.5 41.7 0.0 17.0 1.6 5.4 33.5 14.5 32.1 0.5 0.0 0.0 27.1 143.8 2.2 0.0 12.7 3.5 0.0 40.5 0.0 0.6 0.6 8.1 0.0 15.0 0.9 0.0 0.0 0.5 0.3 37.9 8.8 0.4 0.1 18.7 9.5 11.8 2.9 0.0 6.6 0.4 1.3 2.6 5.3 30.2 0.0 13.5 1.6 0.0 1.7 25.0 ADNP "ADNP1, KIAA0784" ENSG00000101126 "Activity dependent neuroprotector homeobox" Q9H2P0 20 50888916-50931437 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Autism spectrum disorder, Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006371 Supported Approved Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA006371: AB_1078105" "unprognostic (3.40e-2)" "unprognostic (6.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.06e-2)" "unprognostic (1.68e-1)" "unprognostic (6.68e-2)" "prognostic unfavorable (1.65e-5)" "unprognostic (1.73e-1)" "unprognostic (1.80e-1)" "unprognostic (4.38e-2)" "unprognostic (3.11e-1)" "unprognostic (1.39e-2)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (3.63e-1)" "unprognostic (1.90e-2)" "unprognostic (1.08e-1)" 21.1 22.3 31.9 20.2 33.1 25.3 32.6 37.5 40.0 26.6 30.6 23.3 20.1 31.4 42.1 23.9 29.4 22.3 19.4 32.1 32.7 24.9 25.4 24.0 28.9 30.8 31.7 39.3 21.8 36.1 20.5 25.3 30.7 28.6 24.1 43.6 21.9 29.9 35.7 27.9 22.8 29.7 31.2 25.0 26.7 36.6 35.1 44.8 29.6 28.4 35.6 26.7 23.9 36.9 51.2 50.9 103.2 53.7 51.3 47.3 38.8 41.2 48.1 79.0 55.8 80.4 42.3 74.0 51.7 52.9 41.9 62.1 86.6 85.1 89.5 32.6 30.8 54.2 58.1 64.0 48.9 87.7 41.2 47.1 101.3 47.8 85.7 61.2 56.7 46.2 66.7 47.2 51.6 61.6 76.4 61.4 45.5 52.7 42.8 76.2 54.4 55.5 50.9 77.2 81.2 61.9 92.7 138.0 73.6 65.8 62.7 82.5 44.7 68.6 69.4 49.0 45.8 36.3 39.2 104.0 42.2 50.5 47.3 38.5 23.8 22.3 40.5 37.4 42.7 26.0 44.6 36.9 28.3 29.8 43.8 58.4 12.3 31.4 52.8 58.2 32.8 22.5 31.9 33.1 37.5 40.0 32.1 32.7 30.8 31.7 30.7 31.2 35.1 36.9 45.5 9.6 24.4 85.5 31.1 60.0 32.9 22.9 26.7 41.3 46.9 39.2 38.0 38.6 26.4 14.7 25.0 31.4 55.4 25.6 17.6 22.2 26.3 50.0 59.9 33.4 37.1 26.9 75.6 21.9 20.3 32.8 25.0 61.3 17.2 72.5 27.1 29.5 22.5 38.7 93.5 29.3 18.3 27.4 41.0 38.8 31.4 28.9 40.9 77.8 26.7 25.0 20.6 124.1 122.7 28.5 21.1 39.9 27.0 36.1 22.1 23.2 22.0 37.1 39.5 45.9 41.2 27.9 35.2 31.2 52.0 22.2 36.6 42.8 33.7 39.8 AEBP1 ACLP ENSG00000106624 "AE binding protein 1" Q8IUX7 7 44104345-44114562 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Calmodulin-binding, DNA-binding, Repressor" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 103.0;Fibroblasts: 263.2;Leydig cells: 151.6;Peritubular cells: 508.9;Smooth muscle cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.6" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.6" "Cell line enhanced" "Detected in many" "ASC diff: 141.1;BJ: 193.0;BJ hTERT+: 126.0;fHDF/TERT166: 208.9;JURKAT: 145.0;WM-115: 117.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 57.6" "CAB009966, HPA047724, HPA063595, HPA064970" Supported Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2700000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB009966: AB_2225690, HPA047724: AB_2680132, HPA063595: AB_2685052, HPA064970: AB_2685394" "unprognostic (1.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.13e-1)" "unprognostic (7.00e-2)" "unprognostic (8.79e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.31e-9)" "unprognostic (2.88e-3)" "unprognostic (9.58e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-3)" 190.5 59.9 45.0 59.8 56.0 10.6 153.0 38.6 44.8 312.1 28.0 95.3 19.2 268.8 59.6 65.7 199.8 155.9 156.7 47.3 92.9 68.7 20.3 166.0 45.5 114.7 81.5 253.7 28.9 10.1 43.3 89.0 79.6 112.1 25.0 1.3 50.7 213.5 21.3 84.8 79.1 119.3 74.3 54.4 71.2 40.4 52.1 73.3 83.7 14.1 16.7 138.7 198.0 66.6 0.6 0.0 44.5 0.1 141.1 49.6 1.0 193.0 126.0 21.6 4.5 0.0 0.1 5.3 20.9 208.9 0.2 0.1 2.4 3.5 9.1 0.6 0.0 13.3 0.1 0.0 39.6 0.1 0.3 75.8 0.0 72.9 0.1 1.1 9.7 145.0 8.3 0.3 0.0 0.2 86.9 16.1 19.1 0.0 0.4 71.3 1.7 1.7 5.0 0.0 4.9 25.3 0.1 0.3 85.9 41.9 0.4 14.4 34.1 0.0 86.2 0.5 0.3 1.0 0.9 102.8 0.4 0.2 117.9 0.0 0.0 0.0 0.3 0.0 0.2 1.5 0.2 0.0 0.0 1.4 0.9 0.5 0.0 0.1 0.0 7.6 0.0 0.3 45.0 56.0 38.6 44.8 47.3 92.9 114.7 81.5 79.6 74.3 52.1 66.6 23.6 0.0 2.5 32.3 11.8 34.5 5.7 1.3 1.8 0.8 2.0 14.6 26.4 1.5 1.4 7.3 0.0 2.0 22.7 0.0 0.0 0.9 3.1 3.3 103.0 18.0 0.0 1.3 0.1 0.0 3.3 263.2 8.6 2.9 2.5 33.3 30.4 0.6 3.6 0.0 0.3 0.0 0.0 1.8 42.0 18.0 151.6 3.2 85.4 17.8 1.0 0.2 1.0 6.0 0.3 0.4 0.0 508.9 9.7 16.9 0.0 2.2 2.2 0.8 39.5 23.6 173.4 4.0 4.6 1.5 27.4 3.4 4.8 28.7 0.0 2.4 AFF4 "AF5Q31, MCEF" ENSG00000072364 "AF4/FMR2 family member 4" Q9UHB7 5 132875395-132963634 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023690, HPA029634" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA023690: AB_1844633, HPA029634: AB_2673129" "unprognostic (3.24e-2)" "unprognostic (1.86e-2)" "unprognostic (6.17e-3)" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (2.56e-2)" "unprognostic (7.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.13e-2)" "unprognostic (4.94e-2)" "unprognostic (3.52e-1)" "unprognostic (1.16e-2)" "unprognostic (2.77e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (1.69e-1)" 21.4 28.2 10.9 16.9 13.3 43.4 22.8 20.2 15.3 20.3 9.9 18.5 14.4 26.7 18.2 26.8 16.4 26.0 16.5 11.3 18.7 24.3 21.1 19.7 15.4 11.5 16.1 28.9 24.9 36.3 19.5 20.5 10.6 25.1 17.6 47.3 19.1 21.3 25.4 18.5 15.0 23.6 7.8 16.8 25.1 18.0 19.0 19.0 33.2 25.6 17.1 23.1 19.3 15.6 42.5 33.5 45.2 50.3 34.1 40.9 35.3 44.8 47.9 40.4 51.2 49.8 27.2 21.5 51.7 59.2 49.0 20.8 36.8 55.5 67.3 15.4 23.7 26.6 44.6 17.8 43.6 9.4 26.5 48.2 36.2 70.2 70.7 43.5 39.4 19.2 19.4 17.7 51.2 16.0 26.1 10.0 17.4 12.6 13.6 17.3 44.1 8.1 35.0 58.8 35.2 37.0 50.9 12.3 50.4 62.0 26.2 15.0 55.9 48.3 40.8 43.0 48.2 24.3 45.3 19.3 45.2 17.2 33.7 13.0 1.8 3.2 4.0 1.5 3.0 6.2 3.7 2.8 2.2 6.3 3.8 3.3 4.1 3.0 4.1 4.1 1.9 1.3 10.9 13.3 20.2 15.3 11.3 18.7 11.5 16.1 10.6 7.8 19.0 15.6 134.3 80.1 43.9 62.3 98.7 79.7 79.8 52.0 140.0 74.8 94.1 76.7 65.2 57.2 70.8 58.8 158.4 36.4 75.9 69.9 7.9 51.1 244.1 136.4 147.8 79.3 97.6 29.2 99.5 46.2 47.8 98.0 197.2 229.0 43.1 222.1 54.3 25.2 41.9 79.1 85.1 59.1 50.8 62.3 123.7 200.5 69.3 100.9 69.4 60.9 41.6 61.9 39.1 73.9 106.0 75.8 65.5 67.4 93.0 97.3 56.1 35.7 53.2 135.1 78.9 126.5 103.8 34.2 21.5 130.6 86.5 69.9 68.9 89.6 47.2 120.0 AGPS "ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY" ENSG00000018510 "Alkylglycerone phosphate synthase" O00116 2 177392746-177567024 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cataract, Disease variant, Dwarfism, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 262.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030209, HPA030210, HPA030211" Supported Supported Peroxisomes "Intracellular and membrane" NA NA 69000 "Cluster 26: Non-specific - Mitochondria" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Peroxisomes "HPA030209: AB_10600634, HPA030210: AB_10600202, HPA030211: AB_10602195" "unprognostic (7.10e-2)" "unprognostic (1.20e-2)" "unprognostic (1.76e-3)" "unprognostic (3.79e-2)" "unprognostic (8.34e-2)" "unprognostic (3.78e-2)" "prognostic unfavorable (8.62e-6)" "unprognostic (1.23e-2)" "unprognostic (7.23e-2)" "unprognostic (5.41e-2)" "prognostic unfavorable (8.35e-4)" "unprognostic (7.74e-2)" "prognostic favorable (9.45e-4)" "unprognostic (7.18e-2)" "unprognostic (3.46e-1)" "unprognostic (4.94e-3)" "unprognostic (1.92e-2)" 14.3 9.2 4.4 15.6 6.9 19.6 13.9 7.1 6.9 14.3 4.6 20.1 11.1 14.6 6.5 12.7 9.8 11.3 10.4 4.7 6.6 18.1 19.3 13.7 11.9 8.9 7.0 7.8 11.4 18.5 3.4 13.2 8.2 7.0 21.9 6.4 8.3 8.8 11.7 4.5 13.1 21.1 7.8 8.7 9.9 16.3 6.3 16.1 12.6 12.6 12.8 14.6 5.2 11.9 43.1 36.3 23.3 19.0 32.2 33.2 33.3 29.6 21.9 34.5 34.8 70.6 34.0 58.5 59.5 45.0 46.3 47.5 64.4 45.1 47.8 51.4 16.7 77.6 56.5 75.8 31.9 82.3 63.5 28.6 28.7 58.6 44.6 33.3 75.3 42.1 44.9 26.3 45.7 0.1 59.9 22.4 33.3 42.7 30.9 47.0 65.1 32.7 60.0 65.0 22.0 31.3 66.2 5.8 43.0 58.1 0.4 35.4 70.0 29.4 61.9 26.8 64.2 28.7 59.0 23.6 29.4 43.1 11.8 2.6 3.3 5.8 1.9 4.0 2.9 1.7 3.0 2.4 3.6 1.1 2.7 1.6 1.5 2.8 3.6 0.1 4.3 2.2 4.4 6.9 7.1 6.9 4.7 6.6 8.9 7.0 8.2 7.8 6.3 11.9 20.2 16.0 13.1 29.4 10.7 10.8 6.5 15.5 12.0 11.5 19.2 6.7 20.0 20.0 13.0 14.7 2.1 14.1 15.5 25.6 13.7 20.9 262.2 25.2 17.2 14.0 19.8 20.8 53.0 23.2 20.6 23.0 18.8 25.4 64.1 16.6 11.7 31.0 31.8 15.2 61.7 30.4 16.2 30.0 31.8 41.4 14.6 28.7 14.2 56.2 36.0 12.0 21.6 45.8 83.8 23.9 17.4 13.9 14.1 3.8 15.3 46.5 21.6 7.6 6.6 16.8 16.4 41.7 22.2 16.2 9.8 7.0 19.0 22.7 26.0 6.1 AGT SERPINA8 ENSG00000135744 Angiotensinogen P01019 1 230690776-230745576 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1603.7" "Group enriched" "Detected in many" 9 "Cholangiocytes: 985.1;Hepatocytes: 2244.9" "Cancer enriched" "Detected in all" 4 "liver cancer: 1163.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 646.2;THP-1: 243.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025798 Supported "Secreted to blood" NA NA 5940000 65000000000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB025798: " "unprognostic (7.77e-2)" "unprognostic (4.46e-1)" "unprognostic (2.15e-2)" "unprognostic (2.07e-2)" "unprognostic (2.67e-1)" "unprognostic (3.61e-2)" "unprognostic (5.75e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "unprognostic (4.46e-2)" "unprognostic (4.32e-3)" "unprognostic (6.70e-2)" "unprognostic (9.28e-2)" "unprognostic (4.42e-3)" "unprognostic (2.17e-1)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" 11.7 14.6 252.9 2.6 259.8 0.4 4.4 267.5 243.6 9.7 138.2 5.6 2.5 3.2 1.9 2.6 6.0 92.7 154.7 236.0 242.1 52.5 1603.7 5.1 1.0 352.4 314.4 3.5 7.9 6.0 25.8 0.7 304.9 16.3 3.6 26.4 4.9 2.2 43.6 2.0 9.7 5.8 340.5 1.3 4.9 4.1 273.5 1.7 13.2 25.8 0.1 7.0 4.5 322.4 0.2 0.4 0.2 0.2 15.6 0.0 0.9 0.6 0.2 0.0 0.0 80.6 0.1 0.3 0.7 0.2 0.7 0.7 0.0 0.0 0.0 11.4 0.2 0.2 0.3 646.2 1.9 1.0 0.5 26.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 5.5 0.7 0.0 0.2 0.6 0.6 0.1 0.2 0.3 2.4 0.1 0.1 0.3 0.9 0.6 0.4 0.1 5.5 0.1 0.0 243.6 0.1 0.4 1.3 0.4 1.2 3.5 47.0 0.4 0.4 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.9 259.8 267.5 243.6 236.0 242.1 352.4 314.4 304.9 340.5 273.5 322.4 0.8 0.0 1.7 140.0 11.3 0.6 1.1 0.0 0.0 4.7 0.8 0.3 60.0 985.1 0.6 3.7 35.5 0.1 0.0 0.0 25.4 169.8 62.2 0.3 0.4 5.5 0.0 50.8 0.3 10.0 0.2 27.2 0.5 0.1 0.0 0.0 39.3 2244.9 2.1 3.3 1.5 1.1 0.0 56.9 0.4 48.5 4.1 0.9 8.8 5.6 0.6 75.1 0.0 3.5 6.8 13.7 1.2 3.4 0.0 26.2 24.2 146.9 0.1 49.8 13.1 7.2 94.1 0.4 0.4 0.0 0.0 0.7 3.9 0.0 0.4 1.9 AGTR1 "AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R" ENSG00000144891 "Angiotensin II receptor type 1" P30556 3 148697784-148743008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 96.6;placenta: 141.6" "Cell type enhanced" "Detected in some" "Fibroblasts: 53.1;Hepatocytes: 30.9;Leydig cells: 145.1;Sertoli cells: 144.7;Smooth muscle cells: 71.2" "Group enriched" "Detected in many" 8 "breast cancer: 9.6;liver cancer: 9.8;prostate cancer: 6.8;renal cancer: 2.8" "Region enhanced" "Detected in some" "midbrain: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 176.8;ASC TERT1: 24.4;BJ hTERT+ SV40 Large T+: 34.8;HBF TERT88: 53.9;HSkMC: 32.2" "Low region specificity" "Detected in all" HPA003596 Enhanced Uncertain Vesicles NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA003596: AB_1845163" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.48e-4)" "unprognostic (5.28e-3)" "unprognostic (1.55e-1)" "unprognostic (3.46e-1)" "unprognostic (1.28e-2)" "unprognostic (3.26e-2)" "unprognostic (3.08e-2)" "unprognostic (9.25e-3)" "unprognostic (4.11e-2)" "unprognostic (4.79e-2)" "unprognostic (3.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (5.41e-3)" 65.9 38.2 0.3 1.8 0.7 0.0 39.9 0.2 0.4 3.4 0.4 21.1 0.8 3.5 2.7 2.8 9.8 6.2 10.9 0.4 1.4 18.4 96.6 10.4 0.7 2.1 8.1 3.8 3.5 2.8 3.8 141.6 0.9 5.3 4.4 0.9 4.7 4.2 11.6 15.8 4.3 4.6 0.2 9.1 6.5 2.2 0.7 3.0 14.2 13.8 0.2 14.6 6.1 0.2 0.0 1.0 0.8 0.0 176.8 24.4 0.0 0.2 3.9 34.8 20.0 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.0 0.0 53.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 32.2 0.0 3.4 1.8 1.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.2 0.4 0.4 1.4 2.1 8.1 0.9 0.2 0.7 0.2 20.5 0.0 0.6 0.0 0.0 3.4 0.2 0.0 0.0 0.0 1.3 0.9 6.3 2.8 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.1 0.8 0.0 0.3 3.8 23.5 0.0 0.1 7.6 0.3 53.1 0.5 0.0 0.0 0.0 17.5 30.9 0.7 0.0 0.0 0.2 0.0 0.3 3.5 1.7 145.1 0.5 1.8 2.8 0.0 5.7 0.0 0.0 0.1 0.5 0.0 7.5 0.4 1.1 0.0 0.1 0.0 0.1 144.7 7.6 71.2 0.0 1.8 0.3 1.7 0.3 0.5 0.3 0.0 0.1 AHI1 "FLJ20069, JBTS3, ORF1" ENSG00000135541 "Abelson helper integration site 1" Q8N157 6 135283407-135498434 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation" "Developmental protein" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 1121.7;Excitatory neurons: 633.2;Inhibitory neurons: 655.2;Rod photoreceptor cells: 1631.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031698, HPA046684" Approved Approved Centrosome NA NA "Cluster 6: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Centrosome "HPA031698: AB_2673997, HPA046684: AB_2679752" "unprognostic (4.00e-2)" "unprognostic (2.86e-1)" "unprognostic (8.13e-2)" "unprognostic (1.02e-1)" "unprognostic (3.17e-2)" "unprognostic (2.18e-2)" "unprognostic (2.70e-3)" "unprognostic (2.11e-1)" "unprognostic (2.11e-1)" "unprognostic (4.58e-2)" "prognostic favorable (7.51e-5)" "unprognostic (2.81e-2)" "prognostic unfavorable (4.07e-9)" "unprognostic (2.49e-2)" "unprognostic (1.88e-1)" "unprognostic (3.36e-2)" "unprognostic (6.19e-3)" 5.8 9.4 6.2 2.8 4.9 1.7 5.8 12.6 10.6 8.0 5.7 7.0 1.9 7.8 6.1 3.8 8.6 3.2 5.9 4.1 16.4 5.5 5.3 6.4 1.9 5.9 9.2 10.6 9.1 7.0 29.6 3.3 4.8 9.3 3.9 27.2 6.6 5.7 5.5 4.5 4.8 5.0 2.2 2.8 7.0 13.3 19.5 3.6 7.2 3.4 1.9 7.0 6.2 12.7 4.8 6.7 7.9 8.8 11.6 15.0 3.0 9.3 11.7 8.3 14.5 1.7 3.4 6.8 4.6 9.1 8.4 3.2 6.3 1.7 12.5 6.2 6.3 2.5 15.0 4.2 6.0 14.5 2.8 6.2 3.4 12.7 5.1 15.3 8.8 8.1 14.8 0.6 14.0 4.4 4.4 1.7 5.9 2.8 4.9 6.8 4.3 2.7 3.4 3.0 12.2 6.5 12.2 3.9 5.6 5.3 3.2 7.1 6.9 6.9 8.7 11.3 8.2 6.7 11.0 3.5 8.5 2.3 12.7 11.1 2.5 0.1 6.0 0.8 3.4 11.5 5.7 6.0 3.6 14.1 4.3 5.6 0.2 6.4 0.8 21.9 3.3 0.9 6.2 4.9 12.6 10.6 4.1 16.4 5.9 9.2 4.8 2.2 19.5 12.7 32.7 38.5 93.8 162.6 35.6 28.7 38.2 11.2 37.0 296.1 41.1 38.6 26.7 25.8 35.1 58.8 1121.7 25.8 64.0 43.9 13.7 29.5 327.4 92.7 65.1 43.8 101.8 10.7 633.2 44.4 18.2 66.8 61.7 50.7 58.3 49.8 21.0 17.5 13.3 329.7 655.2 52.4 24.4 6.5 19.3 375.4 67.7 20.7 32.0 89.9 9.0 93.4 11.3 171.9 272.1 22.5 43.1 65.1 36.6 30.5 7.1 13.6 65.2 1631.4 52.6 81.6 37.6 137.4 127.1 18.1 22.6 28.6 38.6 52.8 42.5 24.9 AHSG "A2HS, FETUA, HSGA" ENSG00000145192 "Alpha 2-HS glycoprotein" P02765 3 186613060-186621318 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Mineral balance" "Cancer-related genes, Disease variant, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4302 "liver: 5817.6" "Cell type enriched" "Detected in some" 38 "Hepatocytes: 1242.5" "Cancer enriched" "Detected in some" 284 "liver cancer: 1231.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 78 "Hep G2: 2287.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001524, HPA001525, CAB026209" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" NA NA 864000000000 110000000000 "Cluster 48: NK-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "CAB026209: , HPA001524: AB_1078851, HPA001525: AB_1078849" "unprognostic (6.40e-2)" "unprognostic (1.31e-1)" "unprognostic (2.03e-2)" "unprognostic (3.20e-2)" "unprognostic (1.07e-2)" "unprognostic (1.16e-2)" "unprognostic (7.47e-3)" "unprognostic (3.05e-1)" "unprognostic (5.27e-2)" "unprognostic (8.64e-2)" "unprognostic (3.99e-7)" "unprognostic (5.21e-2)" "unprognostic (5.21e-2)" "unprognostic (1.04e-1)" 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 1.3 5817.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 0.0 0.7 0.7 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.9 1.0 2287.3 0.0 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 3.5 0.0 0.0 1.1 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.4 0.0 1.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.2 0.0 0.0 0.0 0.2 0.0 0.1 3.9 0.2 4.3 0.2 0.1 0.9 0.0 32.0 0.6 0.6 2.4 0.1 0.0 0.1 0.0 0.0 28.2 1242.5 1.3 0.0 0.1 0.0 0.0 32.4 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 2.0 0.0 0.0 0.1 AKT1 "AKT, PKB, PRKBA, RAC, RAC-alpha" ENSG00000142208 "AKT serine/threonine kinase 1" P31749 14 104769349-104795751 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Neurogenesis, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 61.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 61.5" "Cell line enhanced" "Detected in all" "MCF7: 558.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002891, CAB003765" Supported Supported Nucleoplasm,Microtubules NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm Microtubules "CAB003765: AB_562035, HPA002891: AB_1078123" "unprognostic (3.30e-2)" "unprognostic (4.27e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (9.17e-3)" "unprognostic (1.55e-3)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "prognostic favorable (4.83e-4)" "unprognostic (3.58e-2)" "unprognostic (1.90e-2)" "prognostic favorable (2.12e-4)" "unprognostic (7.14e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" 71.5 102.7 45.9 57.7 45.5 51.2 61.2 43.7 53.2 52.0 50.4 85.0 50.8 59.5 23.2 70.7 53.7 50.0 105.9 45.2 44.3 54.3 97.3 69.2 51.9 50.5 45.7 43.7 94.3 53.0 35.9 55.4 45.0 67.2 39.6 25.1 67.7 73.0 58.1 45.0 53.3 63.4 47.4 63.7 77.8 23.9 48.0 52.4 52.3 64.9 40.3 72.6 48.4 43.3 77.3 150.5 124.6 186.9 95.2 97.7 136.9 142.3 171.5 204.6 163.6 96.8 92.8 91.2 105.5 196.6 102.8 99.4 89.5 131.9 90.1 214.3 36.2 70.6 90.4 103.2 104.6 117.5 178.0 140.0 109.1 102.9 68.1 98.2 154.4 87.5 62.1 102.2 134.1 558.3 145.3 146.8 32.6 153.5 107.2 137.5 111.9 60.5 94.8 189.5 141.2 117.2 117.3 152.2 88.9 56.8 195.7 170.2 123.5 133.2 63.2 192.3 145.1 105.4 52.6 80.7 113.7 96.7 162.0 6.4 9.9 61.5 10.0 10.3 7.2 5.5 8.7 11.4 7.0 7.2 4.6 10.1 22.6 11.0 12.4 10.0 9.0 6.3 45.9 45.5 43.7 53.2 45.2 44.3 50.5 45.7 45.0 47.4 48.0 43.3 45.8 16.0 27.4 16.6 13.7 12.4 20.0 17.3 15.9 26.3 58.0 39.9 16.1 32.9 17.7 22.0 12.5 19.4 54.2 40.9 13.7 23.6 1.9 17.9 28.1 27.5 30.0 11.3 8.2 35.2 31.8 24.0 26.0 24.8 2.5 40.4 23.2 42.9 23.2 42.1 13.0 37.3 22.4 23.3 21.4 3.3 28.6 28.0 10.6 6.5 23.1 51.2 24.7 8.0 9.6 53.3 22.1 30.9 10.3 38.8 23.5 17.9 14.2 26.6 26.3 24.9 29.1 1.8 5.3 16.2 13.9 23.4 23.3 34.0 33.7 33.4 AKT3 "PKBG, PRKBG, RAC-gamma" ENSG00000117020 "AKT serine/threonine kinase 3" Q9Y243 1 243488233-243851079 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.9" "Group enriched" "Detected in many" 6 "Astrocytes: 457.4;Excitatory neurons: 756.1;Inhibitory neurons: 514.5;Microglial cells: 414.1;Oligodendrocyte precursor cells: 633.3;Oligodendrocytes: 475.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013090, HPA026441" Approved Supported Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB013090: AB_2533692, HPA026441: AB_1844711" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (2.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.96e-1)" "unprognostic (3.77e-1)" "unprognostic (2.32e-1)" "unprognostic (2.28e-1)" "unprognostic (5.47e-3)" "unprognostic (1.37e-1)" "unprognostic (6.71e-2)" "unprognostic (3.64e-3)" "unprognostic (1.29e-1)" "unprognostic (8.14e-2)" "prognostic unfavorable (9.27e-4)" 19.3 9.7 13.4 6.0 17.0 3.8 15.5 59.9 36.6 20.0 0.0 24.5 2.6 22.7 8.6 5.9 20.3 8.2 11.8 22.8 5.6 11.2 4.7 15.3 5.9 1.2 3.9 26.4 4.5 7.4 13.9 13.1 7.4 15.8 4.9 17.0 5.1 15.6 5.9 6.3 11.8 15.7 0.8 8.1 10.2 9.7 20.3 7.0 14.4 11.5 4.6 18.8 14.8 31.1 30.8 7.2 31.0 0.4 16.9 20.6 13.9 20.8 22.5 11.8 12.9 1.1 13.9 0.5 3.0 28.9 12.1 1.2 16.3 8.5 18.9 9.0 15.3 1.0 1.0 0.3 11.7 0.6 6.5 11.3 0.3 15.5 16.9 30.3 30.2 7.2 0.5 1.1 9.0 0.9 7.6 3.3 14.4 0.3 5.1 4.2 19.7 0.6 4.8 4.1 31.4 41.9 1.3 0.5 40.1 19.1 1.9 21.5 25.6 22.7 17.7 1.1 19.5 4.6 4.6 7.1 19.4 5.2 25.3 1.3 0.8 0.1 0.6 0.1 1.1 0.6 0.6 0.6 0.3 0.8 0.6 0.7 0.7 1.4 0.3 0.5 0.1 0.3 13.4 17.0 59.9 36.6 22.8 5.6 1.2 3.9 7.4 0.8 20.3 31.1 65.4 3.2 2.2 457.4 22.2 2.4 15.0 1.3 17.1 43.6 6.1 5.1 5.4 4.3 2.7 27.6 33.3 11.0 24.4 0.0 0.0 11.6 82.8 1.7 35.5 43.7 0.0 5.0 756.1 1.7 8.0 27.9 2.6 1.1 5.1 29.7 48.2 0.6 2.9 42.1 514.5 0.0 2.0 10.5 12.5 72.8 27.4 9.5 7.2 414.1 8.6 20.1 19.6 633.3 475.9 0.7 0.0 35.3 14.4 27.0 0.0 6.9 0.3 35.0 19.7 40.1 35.6 15.0 14.6 1.7 1.7 12.4 27.8 8.3 0.0 12.2 ALDH18A1 "GSAS, P5CS, PYCS, SPG9" ENSG00000059573 "Aldehyde dehydrogenase 18 family member A1" P54886 10 95605941-95656711 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" "Kinase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 120.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 80.5;Granulosa cells: 81.6;Proximal enterocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008333, HPA012604" Approved Enhanced Mitochondria NA NA 48000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA008333: AB_1078125, HPA012604: AB_1844721" "unprognostic (5.97e-3)" "unprognostic (2.08e-2)" "unprognostic (5.75e-2)" "prognostic favorable (4.20e-4)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (8.30e-3)" "unprognostic (7.08e-2)" "unprognostic (4.06e-2)" "unprognostic (8.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.60e-9)" "unprognostic (1.02e-3)" "unprognostic (6.57e-2)" "unprognostic (1.29e-3)" "unprognostic (6.43e-2)" 15.3 16.1 12.2 21.2 12.6 16.7 20.2 12.4 13.1 33.4 21.0 51.9 89.3 18.5 30.9 21.0 21.9 25.2 11.5 12.2 13.6 17.7 24.3 10.8 22.0 12.4 14.7 16.7 61.8 33.5 28.2 26.3 13.1 24.2 49.3 11.4 120.1 24.9 4.3 22.4 73.1 26.3 12.7 12.1 40.5 11.7 14.0 17.2 37.5 5.5 26.9 25.2 14.3 13.1 66.5 61.6 57.9 152.7 76.0 72.9 62.2 75.6 112.8 75.1 93.7 124.4 51.6 223.7 68.9 119.7 36.2 85.6 117.1 77.8 84.6 64.0 92.0 71.2 40.5 177.9 49.7 125.6 76.1 77.0 46.8 61.5 119.1 124.5 79.9 82.6 67.5 46.0 57.1 95.0 114.5 80.5 68.6 109.2 60.7 105.9 66.3 76.9 88.3 49.7 57.5 56.9 60.1 47.1 56.9 66.0 70.5 57.9 66.7 31.1 49.0 80.9 88.2 52.4 41.7 135.8 60.4 142.8 40.7 0.1 2.6 0.2 27.3 5.2 28.7 23.0 24.5 28.3 9.6 16.1 20.7 23.1 0.5 26.3 8.3 5.9 25.8 15.5 12.2 12.6 12.4 13.1 12.2 13.6 12.4 14.7 13.1 12.7 14.0 13.1 4.6 6.4 9.2 7.2 12.6 11.2 8.3 8.9 14.2 6.3 15.6 12.4 4.6 11.5 14.3 20.2 0.0 43.9 6.7 80.5 1.9 13.7 1.3 12.7 18.1 8.0 19.8 17.9 15.7 21.1 31.6 16.2 18.8 16.9 8.2 81.6 5.3 27.3 11.5 10.1 13.6 41.3 8.2 3.5 3.8 1.6 9.3 3.5 16.0 11.2 2.6 7.1 8.2 17.6 12.8 11.7 56.4 12.0 30.1 18.4 79.4 8.4 15.2 3.4 0.0 10.5 10.1 8.2 9.9 17.6 8.1 30.2 9.0 10.8 38.7 9.4 ALDH1A3 "ALDH6, RALDH3" ENSG00000184254 "Aldehyde dehydrogenase 1 family member A3" P47895 15 100877714-100916626 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 134.5;urinary bladder: 125.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 175.4;Endometrial stromal cells: 247.9;Leydig cells: 194.5;Prostatic glandular cells: 580.3;Urothelial cells: 468.7" "Cancer enriched" "Detected in many" 5 "prostate cancer: 80.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 363.3;HaCaT: 441.7;HBEC3-KT: 1096.9;hTERT-RPE1: 347.7;U-2197: 619.0;U-87 MG: 484.7;WM-115: 516.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "olfactory bulb: 4.5;spinal cord: 15.8" "HPA046271, HPA064749" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "HPA046271: AB_10965992, HPA064749: AB_2685344" "unprognostic (6.87e-2)" "unprognostic (2.23e-1)" "unprognostic (6.20e-3)" "unprognostic (1.21e-3)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (6.28e-2)" "unprognostic (5.46e-2)" "unprognostic (9.62e-2)" "unprognostic (4.53e-2)" "unprognostic (3.64e-2)" "unprognostic (2.56e-1)" "unprognostic (1.25e-2)" "unprognostic (2.61e-2)" "unprognostic (2.12e-1)" "unprognostic (7.34e-2)" "unprognostic (6.07e-3)" 83.7 11.4 3.0 41.5 2.7 0.6 30.5 4.7 5.2 37.1 16.2 16.6 15.0 8.2 30.3 28.7 24.9 17.0 12.4 3.1 1.9 8.2 5.3 9.8 3.0 4.8 3.4 6.1 15.0 9.0 7.5 8.4 2.6 134.5 8.9 0.3 93.7 49.3 5.9 3.9 25.2 40.8 2.8 3.1 12.8 16.6 3.3 1.6 2.5 6.9 15.7 125.1 22.3 3.9 363.3 43.5 0.6 0.7 75.0 32.8 1.4 3.2 3.2 1.9 0.8 1.0 285.8 2.6 4.7 97.1 55.7 441.7 8.8 1096.9 6.7 0.1 2.0 1.7 20.1 0.3 25.5 1.4 1.9 23.5 29.8 24.4 4.5 347.7 4.0 0.0 0.7 2.4 1.8 3.8 0.2 1.2 9.0 9.6 316.3 0.7 4.2 2.3 0.2 283.6 0.3 25.4 113.9 94.9 33.3 3.6 9.3 3.2 58.3 0.3 1.0 619.0 14.2 0.7 3.4 1.5 484.7 0.2 516.1 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.0 2.7 4.7 5.2 3.1 1.9 4.8 3.4 2.6 2.8 3.3 3.9 10.0 16.0 6.3 0.3 0.5 0.6 175.4 70.5 4.6 0.0 64.6 18.9 2.0 1.5 141.6 103.0 0.0 9.6 0.9 1.0 3.9 70.5 1.2 20.6 247.9 11.6 3.5 0.0 2.9 1.4 0.5 48.9 1.1 11.7 5.7 0.0 1.8 0.1 1.2 0.0 2.3 2.1 30.5 0.0 1.3 8.5 194.5 3.3 0.0 1.0 0.6 0.0 0.0 36.7 4.6 29.4 0.0 135.4 0.0 580.3 0.1 0.7 78.7 0.0 13.1 20.4 11.5 0.5 0.9 2.9 1.6 4.9 2.0 1.5 0.8 468.7 ALMS1 KIAA0328 ENSG00000116127 "ALMS1 centrosome and basal body associated protein" Q8TCU4 2 73385758-73625166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Cone-rod dystrophy, Deafness, Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.2" "Cell type enhanced" "Detected in many" "Early spermatids: 68.4;Excitatory neurons: 64.9;Late spermatids: 86.6;Oligodendrocytes: 92.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "RH-30: 32.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035277, HPA043200" Enhanced Approved "Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles, Centrosome" Cytosol "HPA035277: , HPA043200: AB_10796689" "unprognostic (2.86e-1)" "unprognostic (9.67e-2)" "unprognostic (2.58e-2)" "unprognostic (4.50e-3)" "unprognostic (1.36e-1)" "unprognostic (6.39e-2)" "unprognostic (2.91e-3)" "unprognostic (7.73e-2)" "unprognostic (1.02e-1)" "unprognostic (8.58e-2)" "unprognostic (4.78e-2)" "unprognostic (1.84e-1)" "unprognostic (3.43e-2)" "unprognostic (1.63e-1)" "unprognostic (7.85e-2)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" 2.6 2.4 5.3 2.4 6.8 5.5 4.3 16.0 5.2 4.1 4.5 3.1 2.3 4.5 4.7 1.9 6.4 2.5 1.6 5.3 4.8 3.5 2.4 3.1 3.2 6.8 6.4 9.8 4.5 4.8 1.7 2.7 6.0 3.5 3.0 10.4 2.9 3.6 0.8 2.9 1.9 3.6 5.1 2.4 2.9 22.2 5.7 8.7 4.6 3.1 2.9 2.6 1.5 7.8 14.3 4.6 9.0 8.2 6.2 5.8 6.7 4.8 5.0 6.2 4.8 4.8 1.5 13.8 3.3 6.7 8.0 6.5 12.3 4.2 8.3 6.7 4.1 7.9 4.4 10.2 4.1 10.9 3.8 4.5 3.7 7.6 3.9 3.9 6.3 9.3 7.4 4.9 7.1 7.0 10.2 14.3 10.6 5.7 3.9 10.8 32.5 5.1 4.1 3.7 7.1 10.0 9.1 1.5 5.2 7.5 1.7 2.5 5.4 8.2 8.3 7.1 11.7 6.6 4.0 10.4 3.7 8.2 4.0 0.2 0.0 0.5 0.2 0.1 0.1 0.2 0.3 0.2 0.0 0.2 0.2 0.3 0.0 0.2 0.1 0.3 0.2 0.0 5.3 6.8 16.0 5.2 5.3 4.8 6.8 6.4 6.0 5.1 5.7 7.8 7.3 6.4 10.3 48.3 5.6 2.4 3.1 2.6 6.8 23.3 4.7 4.8 7.2 7.2 9.1 11.0 25.0 3.3 12.8 4.4 0.0 4.7 68.4 30.6 13.2 8.0 7.3 15.4 64.9 3.7 2.7 8.9 10.7 9.3 5.1 21.8 4.6 2.2 3.3 21.9 55.8 5.2 0.0 3.1 2.7 86.6 8.1 6.3 3.6 31.9 5.3 9.2 5.2 54.3 92.7 3.4 1.3 9.1 10.2 3.2 4.0 1.7 25.2 39.7 6.6 14.8 9.5 30.6 26.7 6.9 3.3 1.9 7.8 11.5 5.3 2.0 ALOX12B 12R-LOX ENSG00000179477 "Arachidonate 12-lipoxygenase, 12R type" O75342 17 8072636-8087716 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 90.2" "Cell type enhanced" "Detected in some" "Horizontal cells: 1.7;Rod photoreceptor cells: 1.2;Spermatogonia: 1.2;Suprabasal keratinocytes: 1.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 4.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.3" "Cell line enhanced" "Detected in some" "A549: 1.1;HEK 293: 1.3;hTCEpi: 1.6;JURKAT: 2.7;OE19: 1.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024002 Supported Supported Vesicles,Cytosol NA NA 7000 "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" Cytosol Vesicles "HPA024002: AB_1844757" "unprognostic (1.27e-2)" "unprognostic (1.59e-2)" "unprognostic (4.28e-3)" "unprognostic (1.38e-2)" "unprognostic (3.94e-3)" "unprognostic (1.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.04e-1)" "unprognostic (4.40e-2)" "unprognostic (9.55e-2)" "unprognostic (6.66e-3)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (8.01e-2)" "unprognostic (3.46e-2)" 0.0 0.0 0.4 0.1 0.5 0.1 2.1 0.4 0.6 5.7 0.0 0.1 0.3 0.0 0.0 5.6 0.2 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.5 0.4 0.2 0.0 0.2 1.2 0.1 0.0 0.5 0.4 0.1 0.6 0.8 0.0 0.4 90.2 0.2 0.0 0.1 0.2 0.2 0.2 0.4 0.6 0.0 0.0 19.1 0.0 15.0 0.1 0.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.2 0.3 0.0 0.0 0.0 1.3 0.0 0.4 0.1 0.0 0.2 0.0 0.0 1.6 0.1 0.5 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.8 0.0 0.9 0.0 0.4 0.4 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.2 0.0 0.4 0.6 0.1 0.2 0.0 0.1 0.5 0.7 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.5 0.4 0.6 0.4 0.2 0.4 0.2 0.5 0.1 0.4 0.1 0.0 0.0 0.0 0.3 0.3 0.1 0.2 0.5 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.8 1.2 0.0 1.8 0.0 0.0 0.0 0.1 0.1 ALOXE3 "E-LOX, eLOX3" ENSG00000179148 "Arachidonate lipoxygenase 3" Q9BYJ1 17 8095900-8119047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "skin 1: 56.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.1;Pancreatic endocrine cells: 6.3;Prostatic glandular cells: 1.8;Spermatocytes: 1.8;Spermatogonia: 1.7;Suprabasal keratinocytes: 1.8" "Group enriched" "Detected in some" 4 "cervical cancer: 1.1;head and neck cancer: 3.9;melanoma: 1.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 6.4;HBEC3-KT: 10.1;hTCEpi: 7.3;hTERT-HME1: 13.7;T-47d: 4.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA023120, HPA078597" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "HPA023120: AB_10959300, HPA078597: AB_2732385" "unprognostic (2.40e-1)" "unprognostic (3.01e-2)" "unprognostic (1.87e-3)" "unprognostic (2.09e-4)" "unprognostic (1.07e-2)" "unprognostic (4.06e-2)" "unprognostic (3.56e-4)" "unprognostic (3.60e-1)" "unprognostic (4.65e-2)" "unprognostic (3.82e-2)" "unprognostic (3.72e-1)" "unprognostic (3.66e-5)" "unprognostic (9.81e-2)" "unprognostic (2.55e-1)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" 0.0 0.0 0.5 0.0 0.3 0.0 1.6 1.9 2.1 0.6 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.4 0.2 0.1 0.7 0.1 0.0 0.1 0.3 0.0 0.1 56.2 0.0 0.0 0.1 0.0 0.0 0.8 1.0 0.0 0.0 0.0 1.2 0.0 1.8 0.5 6.4 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.4 0.1 0.5 0.2 0.2 0.1 2.9 0.4 0.8 10.1 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.3 0.1 13.7 0.0 0.0 0.9 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.7 0.0 0.0 4.4 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 1.9 2.1 0.7 0.4 0.8 0.7 0.7 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 2.1 1.2 0.0 0.0 0.6 0.5 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.4 0.1 0.1 0.2 0.0 0.0 1.2 0.9 1.2 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.8 1.7 0.3 1.8 1.1 0.0 0.0 0.0 0.6 ALPK1 "FLJ22670, KIAA1527, Lak" ENSG00000073331 "Alpha kinase 1" Q96QP1 4 112285509-112442621 "Enzymes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 18.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA027435, HPA027443" Approved Approved Centrosome NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Centrosome "HPA027435: AB_10599614, HPA027443: AB_10599421" "unprognostic (6.24e-2)" "unprognostic (1.92e-1)" "unprognostic (9.30e-2)" "unprognostic (1.69e-2)" "unprognostic (7.40e-2)" "unprognostic (5.45e-2)" "unprognostic (2.55e-2)" "unprognostic (7.47e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-1)" "unprognostic (7.14e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (5.82e-7)" "unprognostic (1.60e-1)" "unprognostic (4.17e-2)" "unprognostic (2.81e-1)" "prognostic favorable (1.17e-4)" 4.8 5.3 1.7 4.4 2.0 10.7 5.1 1.9 2.7 5.4 3.2 4.3 2.4 3.7 3.7 4.4 5.3 4.2 3.1 4.5 1.6 7.2 4.5 5.1 5.4 1.4 1.1 5.4 3.5 4.2 2.5 3.6 1.8 4.9 4.2 2.1 5.4 3.1 1.8 6.9 5.0 4.2 0.5 8.7 4.0 2.1 1.8 5.2 4.2 2.3 6.1 6.0 4.4 2.5 1.6 5.0 1.5 0.3 6.4 10.1 2.1 1.7 3.6 2.6 3.3 0.5 7.8 5.3 3.3 3.3 5.2 1.0 1.7 3.2 3.7 6.7 1.9 3.6 2.0 0.4 10.1 2.2 2.0 12.8 8.3 3.7 7.8 5.7 0.9 2.7 0.9 9.1 5.0 3.1 1.3 2.0 0.3 3.7 1.2 0.6 1.1 1.6 3.9 1.8 0.5 0.8 1.7 6.4 2.8 0.2 2.9 4.1 1.8 2.3 2.0 3.8 1.3 2.2 0.7 4.5 5.8 5.3 2.1 1.6 3.7 1.7 0.2 4.7 0.6 0.9 0.6 0.1 3.7 0.9 0.8 0.6 18.7 0.4 2.2 0.5 0.0 1.4 1.7 2.0 1.9 2.7 4.5 1.6 1.4 1.1 1.8 0.5 1.8 2.5 10.8 12.8 26.8 11.4 7.3 2.9 10.9 11.5 12.5 0.5 8.7 10.7 4.0 4.3 15.5 5.5 0.0 4.9 2.9 10.0 0.0 8.0 11.1 12.0 13.7 8.2 1.2 5.0 5.9 6.7 3.0 9.6 16.3 10.9 6.3 10.9 7.1 7.4 10.1 0.0 1.2 8.6 8.2 13.5 4.6 2.6 3.7 18.7 7.2 73.1 16.1 10.7 1.0 0.5 0.7 7.1 9.0 7.5 2.4 8.8 8.0 5.3 25.7 0.2 6.6 8.4 10.8 0.9 0.7 10.3 4.5 7.3 4.0 7.0 6.4 12.4 ALX1 CART1 ENSG00000180318 "ALX homeobox 1" Q15699 12 85280220-85301784 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 3.9;kidney: 6.1" "Cell type enriched" "Detected in some" 5 "Melanocytes: 32.0" "Cancer enriched" "Detected in some" 10 "melanoma: 16.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 10.4;HEK 293: 23.3;HUVEC TERT2: 17.2;SK-MEL-30: 29.5;THP-1: 18.0;WM-115: 14.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001598, HPA018905" Uncertain Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies" "Nucleoplasm, Golgi apparatus" "HPA001598: AB_1078400, HPA018905: AB_1844783" "unprognostic (4.92e-3)" "unprognostic (8.09e-2)" "unprognostic (1.09e-3)" "unprognostic (1.84e-1)" "unprognostic (6.24e-2)" "unprognostic (2.05e-2)" "unprognostic (9.27e-2)" "unprognostic (1.22e-1)" "unprognostic (3.57e-1)" "unprognostic (2.01e-1)" "unprognostic (1.55e-5)" "unprognostic (8.97e-2)" "unprognostic (1.43e-1)" 0.2 0.0 0.2 0.0 0.2 0.0 0.2 0.1 0.3 1.0 0.4 0.0 0.0 0.7 3.9 0.0 2.3 0.0 0.0 0.2 0.3 6.1 0.0 0.0 0.0 0.2 0.2 1.6 0.0 0.0 0.7 0.0 0.2 0.1 0.0 0.2 1.9 0.9 0.0 1.6 0.0 0.3 0.2 0.0 0.0 0.8 0.2 0.0 0.0 0.8 0.0 0.4 0.3 0.2 0.0 6.0 0.0 0.0 0.7 0.7 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 3.6 0.0 10.4 0.5 0.0 0.0 23.3 0.0 4.1 0.0 0.3 0.0 0.0 0.0 0.0 3.1 0.0 9.3 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 2.7 5.8 0.0 0.0 29.5 4.1 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.0 0.0 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 2.2 0.2 1.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 ALX3 FND ENSG00000156150 "ALX homeobox 3" O95076 1 110059870-110070672 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 7.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.1;Cone photoreceptor cells: 4.2;Microglial cells: 1.0;NK-cells: 1.0;Rod photoreceptor cells: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enriched" "Detected in many" 8 "olfactory bulb: 16.7" "Not detected" "Not detected" HPA074290 Approved "Nucleoli fibrillar center" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoli fibrillar center" "HPA074290: " "unprognostic (4.28e-1)" "unprognostic (4.41e-2)" "unprognostic (2.91e-1)" "unprognostic (2.48e-2)" "unprognostic (1.31e-1)" 1.1 1.9 1.9 1.5 2.2 1.3 0.1 2.1 2.3 0.1 2.6 0.6 2.1 2.4 0.0 2.5 2.2 1.8 1.1 1.6 1.9 1.0 0.1 1.3 2.9 3.1 2.0 2.8 1.6 1.2 0.9 1.0 3.0 1.0 0.0 5.4 2.5 0.0 3.1 7.2 2.9 0.2 1.7 2.7 1.1 1.9 2.6 0.0 2.3 0.4 0.0 0.8 0.1 2.3 3.6 2.5 4.0 6.5 0.0 0.0 8.5 8.7 12.1 0.0 0.0 3.7 1.7 2.1 3.3 0.1 1.4 5.2 0.0 0.0 0.0 5.0 6.7 1.1 4.3 2.3 0.0 2.0 0.9 0.0 0.0 0.0 0.0 4.7 0.0 3.8 3.0 0.5 0.0 4.0 1.5 2.1 4.6 2.6 5.0 3.2 5.2 1.5 0.0 5.0 5.6 7.7 4.2 6.0 5.7 4.5 2.7 3.4 3.6 4.6 4.3 6.4 2.4 3.6 1.2 2.0 5.3 5.0 3.6 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.2 2.1 2.3 1.6 1.9 3.1 2.0 3.0 1.7 2.6 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.8 0.0 0.2 0.1 0.4 0.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 ALX4 "FPP, KIAA1788, PFM, PFM2" ENSG00000052850 "ALX homeobox 4" Q9H161 11 44260440-44310139 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 1.8;choroid plexus: 1.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 20.4;Fibroblasts: 4.3;Leydig cells: 4.7;Microglial cells: 6.5;Skeletal myocytes: 5.5" "Cancer enhanced" "Detected in some" "testis cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 4.0;BJ: 3.4;HAP1: 4.7;HEK 293: 4.8;HEL: 6.8;K-562: 3.2;SiHa: 7.0" "Region enriched" "Detected in some" 8 "olfactory bulb: 9.0" "Region enriched" "Detected in single" 31 "olfactory bulb: 9.0" HPA001903 Supported Nucleoplasm NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "HPA001903: AB_2666495" "unprognostic (7.56e-5)" "unprognostic (1.69e-1)" "unprognostic (5.40e-2)" "unprognostic (2.74e-1)" "unprognostic (7.24e-3)" "unprognostic (2.63e-4)" "unprognostic (1.95e-1)" "unprognostic (2.89e-2)" "unprognostic (2.33e-4)" "unprognostic (5.13e-2)" "unprognostic (1.25e-1)" "unprognostic (1.55e-1)" "unprognostic (1.34e-6)" "unprognostic (3.62e-2)" "unprognostic (2.85e-1)" "unprognostic (2.02e-3)" "unprognostic (2.03e-1)" 0.4 0.0 0.1 0.0 0.1 0.0 1.8 0.1 0.4 0.4 1.9 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.7 0.0 1.0 0.9 0.0 0.3 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.5 0.0 4.0 0.0 0.0 0.0 3.4 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.7 0.0 0.0 1.0 4.8 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.0 0.2 0.3 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 1.1 1.3 20.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.3 0.6 4.7 0.1 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 AMER1 "FAM123B, FLJ39827, RP11-403E24.2, WTX" ENSG00000184675 "APC membrane recruitment protein 1" Q5JTC6 X 64185117-64205708 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 15.3" "Cell type enhanced" "Detected in many" "Sertoli cells: 6.6;Theca cells: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065214, HPA065265" Approved Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" "Vesicles, Plasma membrane" "HPA065214: AB_2685435, HPA065265: AB_2685450" "unprognostic (1.56e-2)" "unprognostic (8.85e-2)" "unprognostic (6.86e-2)" "unprognostic (2.74e-1)" "unprognostic (2.12e-2)" "unprognostic (1.86e-1)" "unprognostic (3.57e-2)" "unprognostic (1.48e-1)" "unprognostic (8.02e-2)" "unprognostic (1.75e-1)" "unprognostic (6.31e-2)" "unprognostic (3.43e-1)" "unprognostic (4.69e-4)" "unprognostic (1.26e-1)" "unprognostic (1.13e-1)" "unprognostic (6.19e-2)" "unprognostic (2.89e-1)" 1.1 1.4 1.6 1.3 1.5 1.2 1.3 1.8 1.6 1.9 0.1 1.5 1.5 1.9 4.0 2.8 2.2 1.0 1.3 1.0 1.6 1.8 2.1 1.2 1.2 1.5 1.4 6.3 2.0 1.6 0.7 0.8 1.5 1.7 1.3 1.3 2.2 2.2 4.1 2.2 1.3 2.8 0.7 1.3 1.6 0.4 1.9 1.6 1.4 15.3 1.6 1.3 1.3 1.0 3.1 2.2 5.8 4.6 2.2 2.1 4.7 1.4 1.2 2.1 1.3 7.3 1.1 5.9 1.8 3.0 1.6 4.3 12.5 4.1 2.0 2.5 2.5 3.7 4.9 4.9 1.6 7.7 0.9 3.0 5.3 1.6 3.2 1.7 1.2 4.6 5.6 5.9 1.1 3.7 5.2 4.0 15.6 4.0 4.4 11.7 9.4 4.3 0.9 1.0 2.6 3.9 3.7 5.0 1.9 4.8 1.6 2.1 0.8 2.5 5.8 6.7 1.9 3.0 2.2 4.4 1.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 1.5 1.8 1.6 1.0 1.6 1.5 1.4 1.5 0.7 1.9 1.0 0.9 0.0 0.0 1.0 1.5 2.2 0.6 0.9 2.8 5.0 1.7 1.5 2.6 4.3 0.3 0.0 2.1 1.1 3.4 1.1 0.0 1.2 0.1 3.3 2.6 1.5 1.2 0.8 0.8 1.6 0.8 1.8 3.6 2.0 0.0 3.9 1.4 2.6 0.4 0.0 1.3 1.0 0.0 1.0 0.3 0.2 2.5 0.5 1.8 1.0 1.2 0.2 0.0 1.0 0.6 0.7 0.5 4.1 2.4 1.2 0.8 0.8 0.0 1.0 6.6 2.3 4.4 0.0 0.2 3.6 2.6 0.7 0.9 6.4 1.6 0.7 AMMECR1 ENSG00000101935 "AMMECR nuclear protein 1" Q9Y4X0 X 110194186-110440318 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Alport syndrome, Deafness, Disease variant, Elliptocytosis, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 83.1;Excitatory neurons: 92.8;Inhibitory neurons: 108.7;Rod photoreceptor cells: 87.3;Syncytiotrophoblasts: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000590, HPA051762" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Mitochondria "HPA000590: AB_2666037, HPA051762: AB_2681596" "unprognostic (7.77e-2)" "unprognostic (1.93e-1)" "unprognostic (2.06e-1)" "unprognostic (5.17e-2)" "unprognostic (1.25e-1)" "unprognostic (6.87e-2)" "unprognostic (1.66e-3)" "unprognostic (6.55e-2)" "unprognostic (5.98e-2)" "prognostic favorable (6.62e-5)" "unprognostic (3.61e-2)" "unprognostic (3.96e-2)" "unprognostic (2.43e-3)" "unprognostic (3.33e-1)" "unprognostic (1.02e-1)" "prognostic favorable (8.44e-4)" "unprognostic (7.82e-2)" 3.6 2.9 1.7 3.7 1.7 13.4 3.4 1.8 2.0 2.9 8.5 3.7 3.1 2.3 2.1 7.9 3.3 2.3 1.1 1.5 1.7 3.4 3.3 2.8 4.2 1.3 1.3 5.5 2.0 2.2 2.0 7.0 1.2 2.2 3.9 14.5 2.8 1.9 1.3 7.4 3.3 2.9 1.0 3.7 3.7 1.6 1.7 4.5 2.4 1.7 5.7 4.8 4.5 1.5 20.3 9.8 7.1 3.4 7.9 11.8 7.8 13.8 12.3 11.1 16.2 15.9 14.4 12.0 6.4 18.4 9.0 9.5 22.7 15.7 11.3 8.4 10.1 16.7 21.7 3.3 19.9 13.5 6.7 6.6 27.3 12.7 22.6 6.0 8.9 5.9 47.1 34.8 8.5 17.2 6.5 4.8 32.6 17.4 19.1 13.7 7.6 21.2 18.8 16.8 11.3 5.3 23.2 22.7 19.9 8.5 5.6 13.3 4.1 7.6 4.6 22.8 12.6 7.1 8.6 18.9 11.6 27.5 25.9 0.6 0.9 0.8 1.6 0.6 2.1 1.6 3.2 2.6 1.5 2.2 2.1 1.9 0.4 0.6 2.7 0.6 2.3 1.0 1.7 1.7 1.8 2.0 1.5 1.7 1.3 1.3 1.2 1.0 1.7 1.5 4.4 0.0 9.8 17.9 11.5 9.6 3.9 10.5 5.7 35.3 7.5 4.4 4.2 8.6 8.9 3.7 52.1 27.2 9.5 8.9 23.5 9.2 0.5 10.5 7.7 9.6 15.0 83.1 92.8 12.0 9.9 12.8 13.7 13.4 2.5 14.4 19.6 8.4 7.1 1.7 108.7 11.2 12.2 7.6 3.1 2.1 12.8 7.3 3.6 21.5 9.4 7.1 14.4 35.7 19.2 11.5 3.7 17.3 8.0 9.1 10.3 10.2 10.4 87.3 13.1 6.7 8.4 2.2 6.9 17.4 26.7 86.5 13.0 34.7 10.5 15.7 AMPD2 SPG63 ENSG00000116337 "Adenosine monophosphate deaminase 2" Q01433 1 109616104-109632051 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Horizontal cells: 52.2;Macrophages: 52.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 19.4;eosinophil: 19.2;intermediate monocyte: 40.7;myeloid DC: 18.9;neutrophil: 61.1;non-classical monocyte: 44.6" "Group enriched" "Detected in all" 5 "dendritic cells: 18.9;granulocytes: 61.1;monocytes: 44.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027137, HPA045760" Approved Enhanced Cytosol NA NA 230000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Cytosol "HPA027137: AB_2672129, HPA045760: AB_2679443" "unprognostic (2.78e-2)" "unprognostic (1.21e-1)" "unprognostic (1.50e-1)" "unprognostic (1.43e-3)" "unprognostic (9.01e-2)" "unprognostic (5.25e-2)" "unprognostic (3.91e-3)" "unprognostic (1.71e-1)" "unprognostic (4.02e-1)" "unprognostic (1.23e-1)" "unprognostic (8.10e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.78e-10)" "unprognostic (9.16e-2)" "unprognostic (2.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.60e-1)" 9.3 17.5 31.2 12.0 41.6 28.6 7.4 22.9 34.7 13.1 36.6 7.5 10.7 11.5 4.1 7.2 13.1 8.8 7.2 34.8 37.0 10.5 16.2 13.4 7.6 34.7 31.7 17.5 10.0 9.4 45.8 7.6 33.6 10.8 4.1 10.5 9.2 12.0 3.3 8.5 10.8 7.1 27.9 19.0 8.6 4.3 39.3 4.9 10.6 1.5 5.9 7.5 11.4 29.0 20.6 22.5 20.5 20.1 18.0 18.7 8.6 25.6 57.2 24.9 25.0 19.1 7.0 10.5 21.8 39.1 16.0 11.3 15.8 20.0 13.4 13.0 20.7 46.0 15.6 19.3 24.9 15.7 45.7 23.3 13.2 32.5 24.1 28.2 26.7 17.0 17.4 13.0 16.0 23.2 26.7 29.0 20.6 17.1 22.9 18.6 15.8 17.3 24.2 8.7 19.3 22.4 17.4 19.8 24.6 5.7 10.4 16.2 16.7 27.7 39.0 33.7 25.4 48.4 28.4 12.1 50.8 25.9 35.1 0.5 19.4 19.2 5.3 40.7 8.0 5.3 5.2 4.9 18.9 2.7 6.4 5.1 61.1 4.3 44.6 2.6 4.0 12.3 31.2 41.6 22.9 34.7 34.8 37.0 34.7 31.7 33.6 27.9 39.3 29.0 3.6 3.2 5.5 13.7 9.4 8.9 5.4 5.0 9.1 41.0 8.8 11.4 3.2 12.8 5.4 0.0 62.6 4.9 10.0 4.2 7.9 9.8 3.5 4.4 9.4 7.1 17.5 5.0 13.3 11.2 8.6 12.6 14.3 5.5 3.8 11.0 6.1 20.5 10.8 52.2 17.6 9.6 2.0 42.1 42.0 1.3 13.1 52.5 5.4 6.5 16.1 10.5 6.2 12.1 10.6 10.3 3.0 21.4 11.1 11.1 6.1 4.5 4.2 7.2 13.1 8.8 10.6 4.2 3.8 7.9 8.1 2.6 15.4 8.5 10.7 4.0 ANAPC1 "APC1, MCPR, TSG24" ENSG00000153107 "Anaphase promoting complex subunit 1" Q9H1A4 2 111611639-111884690 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Cancer-related genes, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036329, HPA036330, HPA042998" Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Vesicles "HPA036329: AB_10670714, HPA036330: AB_2675065, HPA042998: AB_2678263" "unprognostic (1.74e-1)" "unprognostic (5.04e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.49e-1)" "unprognostic (2.15e-1)" "unprognostic (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.94e-2)" "unprognostic (2.59e-1)" "unprognostic (3.65e-2)" "unprognostic (1.23e-1)" "unprognostic (2.13e-2)" "unprognostic (1.94e-1)" "unprognostic (1.98e-1)" "unprognostic (1.15e-2)" "unprognostic (1.92e-1)" 6.4 4.8 4.1 9.5 5.1 8.3 9.2 4.8 5.1 6.9 9.8 9.9 8.3 8.0 4.9 8.1 7.8 5.8 5.8 4.7 3.6 6.2 5.6 5.4 12.1 4.1 4.1 8.4 6.3 10.4 4.6 7.7 5.1 6.4 10.5 7.9 5.4 6.2 12.2 6.8 6.5 7.6 3.7 7.8 6.6 10.2 4.0 12.6 6.3 9.4 12.4 8.4 5.8 5.2 42.4 31.0 33.1 23.9 14.9 18.4 32.6 25.0 18.8 30.3 26.5 60.4 26.6 72.7 19.9 23.0 36.0 35.4 51.0 28.4 40.4 31.7 31.9 81.6 27.6 37.1 14.3 85.0 27.4 13.8 14.3 44.9 40.8 15.4 29.5 34.9 75.8 30.8 21.5 20.2 51.9 25.5 50.3 18.3 26.1 51.1 39.4 41.1 19.1 41.6 26.2 16.0 26.2 23.9 22.8 21.8 14.1 30.1 20.9 26.5 28.5 21.7 26.9 23.0 52.5 67.1 21.5 36.9 21.9 0.0 2.1 0.6 4.2 2.2 6.1 4.0 3.8 3.6 3.9 3.1 5.4 5.2 0.4 4.8 1.9 1.8 1.8 3.3 4.1 5.1 4.8 5.1 4.7 3.6 4.1 4.1 5.1 3.7 4.0 5.2 14.5 3.2 8.2 17.0 20.3 14.3 20.5 7.6 22.2 11.2 12.1 11.8 7.5 8.6 6.0 3.7 14.6 12.2 25.4 7.2 5.9 5.9 6.6 13.5 13.4 11.0 11.4 17.9 32.5 5.9 12.7 12.0 12.2 11.7 8.2 19.2 8.6 12.8 9.0 20.2 32.6 11.1 14.2 8.4 11.8 8.6 10.2 12.2 7.2 12.2 8.8 7.7 13.4 21.6 31.3 7.1 5.4 9.4 14.4 24.6 5.6 8.8 8.2 16.0 13.1 15.9 11.5 17.3 21.0 18.0 20.2 6.7 21.2 12.2 14.5 23.4 ANKH "ANK, CCAL2, CMDJ, CPPDD, HANK, SLC62A1" ENSG00000154122 "ANKH inorganic pyrophosphate transport regulator" Q9HCJ1 5 14704800-14871778 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Phosphate transport, Transport" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 160.1;Hofbauer cells: 208.8;Inhibitory neurons: 214.5;Oligodendrocytes: 261.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068104 Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA068104: AB_2685954" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (6.58e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.83e-2)" "unprognostic (2.11e-1)" "unprognostic (2.38e-2)" "unprognostic (2.99e-1)" "unprognostic (1.54e-3)" "unprognostic (1.76e-3)" "unprognostic (1.71e-1)" "unprognostic (8.66e-2)" "unprognostic (6.46e-2)" 9.9 10.6 22.1 6.6 23.8 8.0 9.9 33.9 29.3 5.5 26.6 12.8 16.8 7.1 4.9 7.4 7.7 9.4 32.2 22.5 25.5 8.1 21.4 7.1 8.5 25.3 28.2 16.0 15.2 19.2 22.8 8.5 25.1 32.7 11.4 25.1 14.3 9.2 40.9 20.3 15.0 8.5 24.9 6.8 7.3 1.9 26.8 11.5 10.7 37.6 14.1 7.3 7.4 28.8 7.2 5.4 6.7 1.1 13.8 32.3 3.2 6.8 13.7 2.6 2.7 4.3 9.0 16.9 15.7 9.4 6.2 4.6 4.6 7.5 3.0 6.7 11.3 0.4 47.8 11.6 4.6 4.1 1.3 10.2 13.0 8.1 9.2 9.2 5.5 12.3 3.5 35.2 8.7 9.6 6.9 13.3 2.6 9.5 6.0 9.8 3.3 15.3 0.0 2.3 16.4 4.5 33.3 5.3 7.5 6.1 0.3 1.5 5.4 6.9 6.9 11.5 12.6 9.2 9.3 13.0 23.8 15.1 29.0 0.6 0.2 0.0 1.4 0.4 2.3 1.5 2.9 2.3 0.3 1.6 3.3 1.5 0.3 0.3 0.9 0.3 4.6 0.4 22.1 23.8 33.9 29.3 22.5 25.5 25.3 28.2 25.1 24.9 26.8 28.8 50.1 25.6 19.1 64.6 15.4 25.2 79.1 33.7 40.9 58.0 29.7 15.5 73.4 7.2 10.8 7.3 127.2 76.4 21.1 58.2 5.9 1.7 1.2 7.1 14.9 25.4 41.8 69.9 160.1 11.8 6.1 25.6 8.2 16.9 17.7 9.8 12.5 32.7 208.8 20.2 214.5 37.7 8.2 89.3 29.9 1.9 5.0 42.6 10.6 106.8 3.4 20.1 21.6 95.5 261.5 6.8 31.4 31.6 14.7 55.4 44.6 10.2 6.4 50.1 0.0 32.8 12.3 2.3 7.2 10.1 10.7 42.0 25.9 8.6 37.3 22.3 ANKLE2 "KIAA0692, Lem4, LEMD7" ENSG00000176915 "Ankyrin repeat and LEM domain containing 2" Q86XL3 12 132725503-132761832 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 215.7;Urothelial cells: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003602, HPA074838" Uncertain Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum, Plasma membrane" "HPA003602: AB_1858349, HPA074838: " "unprognostic (4.43e-2)" "unprognostic (6.92e-2)" "unprognostic (7.97e-2)" "unprognostic (9.84e-3)" "unprognostic (1.97e-2)" "unprognostic (5.81e-2)" "prognostic unfavorable (3.97e-6)" "unprognostic (3.19e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (4.76e-2)" "unprognostic (6.10e-2)" "prognostic unfavorable (1.90e-8)" "unprognostic (1.42e-1)" "unprognostic (1.42e-1)" "unprognostic (6.92e-3)" "unprognostic (2.09e-1)" 30.0 37.6 12.4 27.0 13.3 38.4 27.8 15.2 16.6 25.4 21.9 23.8 17.8 24.9 19.0 33.6 25.2 17.4 22.0 13.8 14.1 21.8 22.9 31.3 31.6 12.3 12.4 27.1 24.6 17.9 23.1 20.4 12.3 23.9 16.1 12.3 26.1 15.6 29.3 36.9 33.3 21.9 12.0 37.9 24.1 55.7 14.3 26.2 23.3 18.3 31.2 25.0 27.6 13.2 50.7 46.4 47.3 29.5 26.9 42.1 59.1 60.2 44.7 59.0 45.0 53.2 33.6 39.5 30.7 53.1 39.5 59.2 41.8 54.8 56.2 17.0 51.6 50.1 84.0 25.2 29.9 54.6 34.0 39.1 54.9 56.2 41.3 108.8 42.8 32.0 46.1 15.1 61.2 36.4 51.1 89.4 40.1 24.8 43.9 58.0 31.1 16.7 42.6 64.9 57.9 35.6 77.7 32.4 27.1 44.1 56.9 39.1 61.5 70.5 50.9 38.0 68.1 27.9 29.5 47.9 54.7 35.8 40.5 0.9 1.2 4.4 1.8 1.1 2.4 2.7 2.6 2.8 1.7 2.8 2.4 2.0 0.7 2.7 1.3 1.7 2.6 0.7 12.4 13.3 15.2 16.6 13.8 14.1 12.3 12.4 12.3 12.0 14.3 13.2 38.0 73.7 31.2 18.3 43.2 67.3 92.0 38.2 32.5 32.3 31.2 27.1 24.6 27.1 51.3 31.3 45.9 29.2 41.1 33.8 1.9 33.2 109.1 58.6 52.4 36.3 20.8 23.1 21.0 32.7 35.5 35.7 35.2 119.2 18.4 38.3 22.9 12.9 20.1 32.0 17.8 18.0 24.4 19.7 47.6 24.5 25.1 35.5 33.8 16.9 40.6 21.9 47.4 18.1 18.4 101.9 24.8 28.2 47.6 116.9 18.8 8.5 32.3 39.7 26.3 39.2 40.5 215.7 61.8 44.8 72.9 36.5 44.7 31.6 24.0 168.7 ANKRD11 "LZ16, T13" ENSG00000167522 "Ankyrin repeat domain 11" Q6UB99 16 89267630-89490561 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019288, HPA041593, HPA049470" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB019288: , HPA041593: AB_2677567, HPA049470: AB_2680780" "unprognostic (7.31e-2)" "unprognostic (6.35e-2)" "unprognostic (1.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.82e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (6.39e-4)" "unprognostic (1.81e-1)" "unprognostic (1.83e-2)" "unprognostic (1.78e-1)" "unprognostic (4.81e-2)" "prognostic unfavorable (7.67e-4)" "unprognostic (1.56e-3)" "unprognostic (1.79e-1)" "unprognostic (7.93e-2)" "unprognostic (5.78e-3)" "unprognostic (2.16e-1)" 24.2 21.1 33.1 26.0 29.3 53.9 14.5 23.2 39.1 18.0 18.7 17.6 21.4 22.0 12.8 22.5 18.4 18.6 22.3 36.8 22.1 15.7 12.2 18.9 26.3 29.8 25.7 29.2 26.6 24.7 24.1 17.9 25.3 16.1 13.6 14.1 20.1 17.0 24.8 35.0 21.0 14.5 19.2 26.6 21.7 18.4 26.7 24.9 19.4 15.0 19.0 19.3 16.5 28.8 55.5 67.9 66.8 51.5 40.3 41.4 64.5 61.7 41.1 36.5 25.8 79.7 57.8 51.0 41.6 44.9 41.1 54.6 46.0 56.8 41.2 25.5 55.3 40.3 49.3 64.7 60.8 30.0 44.0 46.4 56.4 47.9 61.5 52.8 44.4 84.1 88.4 39.6 46.5 52.5 50.1 75.2 58.8 28.7 61.9 101.6 77.0 43.3 38.0 45.7 39.1 47.9 89.0 18.5 65.1 33.9 43.3 46.6 83.2 76.4 71.4 42.9 68.7 71.5 27.1 62.9 61.6 48.6 42.2 7.6 2.9 3.0 2.7 3.1 3.1 2.6 3.1 3.3 1.6 3.0 2.7 2.4 8.5 7.1 5.1 5.4 3.3 1.5 33.1 29.3 23.2 39.1 36.8 22.1 29.8 25.7 25.3 19.2 26.7 28.8 133.0 131.4 103.0 94.7 136.3 116.5 150.3 49.5 91.6 181.3 57.4 65.8 233.3 84.4 52.5 71.7 158.4 42.7 203.7 109.7 31.3 80.1 118.5 200.9 162.6 135.4 106.9 58.5 122.1 72.7 36.3 118.2 96.8 312.8 55.7 164.5 80.7 69.4 48.4 156.5 97.7 89.8 30.5 63.5 117.9 39.5 103.8 112.0 48.0 119.0 110.9 83.1 146.2 117.1 110.0 122.4 66.9 106.1 143.3 147.6 64.6 35.1 45.6 112.9 39.5 148.3 126.3 92.2 98.9 102.6 122.2 38.7 133.8 137.4 87.3 179.0 ANKS6 "ANKRD14, FLJ36928, NPHP16, SAMD6" ENSG00000165138 "Ankyrin repeat and sterile alpha motif domain containing 6" Q68DC2 9 98731329-98796965 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.8;Inhibitory neurons: 48.6;Oligodendrocytes: 54.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA008355 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoli "Nucleoplasm, Cytosol" "HPA008355: AB_2058277" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (9.31e-2)" "unprognostic (9.15e-3)" "unprognostic (6.90e-3)" "unprognostic (1.22e-1)" "unprognostic (4.29e-3)" "unprognostic (4.10e-2)" "unprognostic (1.48e-1)" "unprognostic (3.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.94e-2)" "prognostic favorable (3.44e-5)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (3.95e-2)" "unprognostic (2.68e-1)" 5.7 4.8 8.0 3.2 8.8 1.5 4.7 14.3 10.0 9.5 7.6 10.5 4.2 8.9 4.9 8.7 10.2 3.3 3.9 8.1 7.7 9.4 2.7 6.6 2.4 12.5 8.9 10.3 12.8 5.5 4.8 2.0 12.4 5.5 4.9 2.2 5.4 2.3 3.7 5.3 7.7 4.9 8.2 3.2 11.5 5.7 10.1 2.6 13.6 1.0 2.9 8.7 5.2 9.7 8.2 12.3 10.9 19.3 9.0 7.3 7.4 5.9 10.0 6.5 7.7 6.7 5.8 15.2 4.4 8.4 9.2 23.9 8.1 9.9 3.4 21.2 8.3 3.6 7.7 2.9 8.8 2.0 2.3 8.9 12.0 8.7 8.9 7.9 7.4 13.8 26.0 3.5 5.0 13.5 0.9 3.9 17.3 36.3 12.2 10.2 26.8 1.2 11.7 5.1 7.1 8.1 2.5 14.2 6.7 8.8 0.0 4.1 7.6 6.5 7.2 18.4 5.8 6.8 12.1 2.4 9.4 6.8 9.8 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.4 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 8.0 8.8 14.3 10.0 8.1 7.7 12.5 8.9 12.4 8.2 10.1 9.7 3.5 6.4 10.5 16.0 2.4 1.8 0.9 8.2 5.2 12.0 1.5 2.2 4.4 10.0 7.7 12.9 8.4 3.1 1.5 5.1 3.9 4.2 3.0 3.7 5.3 3.2 4.9 0.8 52.8 8.9 2.7 4.9 7.7 3.9 1.3 6.2 1.8 1.7 1.9 0.0 48.6 7.1 0.0 1.3 0.9 5.8 2.8 0.9 0.0 9.4 0.7 1.9 2.1 14.1 54.2 9.3 3.1 4.5 1.4 3.9 4.8 5.9 11.1 0.8 0.0 2.7 3.2 3.8 5.9 5.6 1.1 1.1 2.4 6.2 10.4 2.9 AP1B1 "ADTB1, AP105A, BAM22, CLAPB2" ENSG00000100280 "Adaptor related protein complex 1 subunit beta 1" Q10567 22 29327680-29388583 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065226, HPA068520" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 660000 "Cluster 39: Non-specific - mRNA processing" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "Vesicles, Cytosol" "HPA065226: AB_2685438, HPA068520: AB_2685998" "unprognostic (1.78e-1)" "prognostic favorable (4.81e-4)" "unprognostic (2.40e-1)" "unprognostic (2.21e-2)" "unprognostic (2.37e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.55e-5)" "unprognostic (4.99e-2)" "unprognostic (1.59e-1)" "unprognostic (1.27e-1)" "unprognostic (4.98e-3)" "unprognostic (1.60e-1)" "prognostic favorable (7.24e-6)" "unprognostic (1.85e-2)" "unprognostic (3.78e-2)" "unprognostic (2.94e-2)" "unprognostic (3.76e-2)" 30.7 46.7 38.0 47.2 38.3 45.8 26.4 37.3 45.2 22.8 35.6 34.9 43.3 22.7 12.1 63.0 23.5 30.4 23.9 36.1 40.8 34.8 34.8 30.1 57.8 44.2 44.6 17.5 38.3 67.0 39.2 44.8 43.7 38.3 30.1 35.3 40.3 25.9 24.5 47.2 45.6 27.1 41.4 52.6 40.9 24.7 52.7 34.2 29.6 20.5 54.4 39.4 32.2 48.8 84.6 47.5 49.3 50.2 37.0 27.0 60.0 59.8 65.5 71.2 68.2 74.4 33.2 46.1 37.2 68.4 33.0 74.6 71.5 97.6 45.2 58.2 102.0 79.1 60.8 42.0 38.9 114.1 99.9 38.6 36.0 67.5 55.0 33.0 98.7 17.2 54.6 54.9 48.3 93.7 45.5 36.8 37.3 124.8 53.3 89.0 54.3 119.9 50.2 194.5 75.9 52.2 74.0 82.5 36.4 33.5 66.7 49.5 84.6 79.1 48.8 46.0 62.1 60.4 32.5 84.6 56.1 48.1 46.7 0.0 29.3 5.7 9.2 29.2 9.1 16.2 6.3 7.9 28.7 18.2 4.9 5.2 3.0 7.2 31.7 9.0 8.8 24.2 38.0 38.3 37.3 45.2 36.1 40.8 44.2 44.6 43.7 41.4 52.7 48.8 17.8 12.8 16.4 27.7 53.0 7.1 9.3 16.7 16.5 26.3 26.2 20.8 16.1 21.5 16.4 22.0 39.6 52.3 15.1 69.6 23.5 41.2 7.5 16.4 11.6 19.8 21.6 40.0 24.1 40.7 30.1 12.1 33.6 30.1 5.1 13.2 35.3 34.3 138.9 45.4 25.6 24.9 18.3 95.5 24.2 13.1 11.8 65.7 12.4 51.5 29.8 28.4 9.2 16.1 14.0 65.9 33.2 12.4 28.5 17.5 51.2 30.1 14.5 42.1 6.6 17.8 12.7 23.5 17.6 33.0 9.1 68.3 17.0 39.6 36.2 18.1 AP1S1 "AP19, CLAPS1, EKV3, SIGMA1A, WUGSC:H_DJ0747G18.2" ENSG00000106367 "Adaptor related protein complex 1 subunit sigma 1" P61966 7 101154456-101161596 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Ichthyosis, Mental retardation, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 344.4;Proximal enterocytes: 241.3;Proximal tubular cells: 304.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060945 Supported Supported "Golgi apparatus,Vesicles" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus, Vesicles" "HPA060945: AB_2684393" "unprognostic (1.98e-2)" "unprognostic (5.41e-3)" "unprognostic (1.02e-1)" "unprognostic (3.34e-2)" "unprognostic (2.98e-3)" "unprognostic (8.70e-3)" "unprognostic (7.06e-3)" "unprognostic (1.12e-1)" "unprognostic (1.76e-1)" "unprognostic (7.79e-2)" "unprognostic (1.34e-1)" "unprognostic (3.75e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" 14.4 24.6 72.2 13.9 75.7 5.8 17.2 43.7 82.6 18.3 34.6 28.6 39.0 16.9 17.0 34.2 13.8 12.8 11.8 85.2 59.6 41.2 36.2 14.7 11.9 53.6 51.9 13.5 21.9 22.8 31.0 15.9 53.4 22.2 22.4 14.6 20.3 9.3 6.4 39.2 30.3 12.7 46.1 20.2 22.0 16.4 62.5 19.1 15.2 8.5 13.6 20.1 19.5 62.7 121.0 87.3 63.3 118.4 42.8 70.4 138.2 76.8 51.1 50.8 52.8 47.3 147.5 24.9 127.5 84.6 97.1 59.0 35.3 116.0 45.6 57.0 56.6 16.8 52.0 61.4 54.2 46.8 87.7 79.1 91.0 49.4 20.6 76.7 76.8 54.1 56.7 103.2 129.9 292.1 40.4 107.8 97.8 177.0 188.2 24.9 27.2 54.6 127.8 88.8 47.5 157.7 40.4 121.1 151.4 101.6 50.7 46.8 79.0 74.1 132.3 27.6 55.2 21.4 51.4 48.4 195.2 50.1 152.9 0.5 3.3 0.3 2.3 3.1 2.2 2.6 3.2 2.5 4.6 2.0 1.9 1.8 1.2 1.3 1.8 5.0 3.3 2.4 72.2 75.7 43.7 82.6 85.2 59.6 53.6 51.9 53.4 46.1 62.5 62.7 34.4 6.4 0.0 2.3 17.9 38.7 29.7 173.0 46.7 30.7 54.8 49.0 1.1 45.8 72.9 55.2 8.4 170.7 19.8 88.4 344.4 128.2 2.5 28.8 34.2 36.7 90.3 16.2 21.2 111.7 101.3 27.7 42.8 31.9 5.7 85.3 28.9 43.0 95.2 30.3 10.3 96.5 116.0 24.8 21.6 3.4 35.1 27.3 53.4 7.5 58.0 34.1 17.5 2.5 9.8 183.3 86.1 21.8 17.4 34.9 241.3 304.8 34.9 22.3 19.7 11.4 38.4 13.1 70.9 51.4 45.5 60.5 19.5 157.4 119.9 38.2 APC2 APCL ENSG00000115266 "APC regulator of WNT signaling pathway 2" O95996 19 1446302-1473244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 64.5" "Cell type enhanced" "Detected in some" "Astrocytes: 142.4;Bipolar cells: 50.4;Excitatory neurons: 26.8;Horizontal cells: 45.4;Inhibitory neurons: 27.5;Muller glia cells: 29.4;Oligodendrocyte precursor cells: 28.1" "Cancer enriched" "Detected in some" 27 "glioma: 17.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.8;SCLC-21H: 9.3;SH-SY5Y: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078002 Supported "Cytokinetic bridge,Midbody,Cytosol" Yes No "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Cytokinetic bridge, Midbody" Cytosol "HPA078002: AB_2686874" "unprognostic (1.78e-3)" "unprognostic (1.65e-1)" "unprognostic (2.88e-5)" "unprognostic (3.64e-2)" "unprognostic (3.59e-1)" "unprognostic (1.52e-2)" "unprognostic (1.00e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (1.38e-2)" "unprognostic (1.30e-2)" "unprognostic (3.45e-2)" "unprognostic (9.49e-3)" "unprognostic (7.39e-2)" "unprognostic (3.70e-2)" "unprognostic (4.99e-2)" "unprognostic (1.98e-3)" 0.1 2.4 41.5 0.0 27.3 0.0 0.0 41.4 42.4 0.1 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.1 0.3 37.1 20.8 0.0 0.0 0.0 0.0 64.5 42.3 0.0 0.3 0.0 6.2 0.0 54.9 0.1 0.0 2.7 0.2 0.0 0.2 0.1 0.4 0.1 38.3 0.0 0.3 1.0 54.6 0.0 0.1 0.0 0.0 0.1 0.2 49.0 0.2 0.6 7.8 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.0 0.0 1.0 0.1 0.0 0.4 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.6 0.0 0.0 9.3 31.7 1.1 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.6 0.1 0.1 1.7 0.5 0.2 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.5 27.3 41.4 42.4 37.1 20.8 64.5 42.3 54.9 38.3 54.6 49.0 0.3 0.0 0.0 142.4 0.3 0.0 0.2 0.2 1.2 50.4 0.4 0.4 3.4 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.1 0.5 0.5 0.5 0.0 0.0 26.8 0.0 0.1 0.3 0.0 0.6 0.0 0.2 0.0 0.0 0.1 45.4 27.5 0.0 0.0 0.0 0.0 0.7 0.3 0.1 0.0 3.7 0.0 29.4 2.1 28.1 17.8 0.0 0.0 0.7 0.0 0.1 0.2 0.2 0.0 11.1 0.0 0.6 0.4 0.4 0.7 2.4 0.0 0.0 0.3 0.2 0.1 0.2 AQP5 ENSG00000161798 "Aquaporin 5" P55064 12 49961872-49965682 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 622.6;testis: 222.0" "Group enriched" "Detected in many" 7 "Early spermatids: 1542.9;Late spermatids: 4265.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 87.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "OE19: 223.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA065008 Enhanced Approved "Plasma membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA065008: AB_2685401" "unprognostic (4.67e-3)" "unprognostic (5.00e-2)" "unprognostic (3.30e-1)" "unprognostic (6.00e-3)" "unprognostic (1.92e-3)" "prognostic favorable (1.75e-5)" "unprognostic (4.13e-3)" "unprognostic (1.02e-2)" "unprognostic (9.39e-2)" "unprognostic (3.70e-3)" "unprognostic (2.88e-3)" "unprognostic (2.46e-3)" "unprognostic (1.69e-4)" "unprognostic (2.53e-1)" "unprognostic (5.28e-2)" "unprognostic (2.51e-3)" "unprognostic (9.11e-3)" 2.9 0.8 2.7 0.1 3.7 0.2 17.1 3.3 2.7 12.9 1.5 0.4 15.3 2.7 0.2 16.5 0.7 2.8 4.0 2.4 2.9 1.9 0.1 7.6 0.0 3.3 3.9 0.2 2.0 3.0 1.2 0.0 3.1 1.3 0.0 1.0 622.6 1.0 0.2 112.7 0.1 0.3 2.6 0.4 52.3 222.0 3.8 0.0 1.6 0.0 0.1 0.3 0.4 2.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.7 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.7 223.2 0.0 10.1 0.0 0.0 0.3 0.0 0.2 0.1 0.8 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.7 3.3 2.7 2.4 2.9 3.3 3.9 3.1 2.6 3.8 2.6 0.5 57.7 3.1 0.0 0.1 1.3 0.5 18.3 0.0 0.8 53.9 48.0 0.3 0.0 56.4 7.3 0.0 0.0 0.1 0.0 0.0 0.1 1542.9 1.5 0.1 1.8 0.0 0.0 0.0 0.2 0.0 1.4 34.7 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 26.4 0.0 1.6 4265.6 28.6 1.7 295.3 0.0 0.0 53.7 0.0 3.0 0.1 7.2 0.0 19.2 0.3 1.6 0.0 0.0 9.7 1.7 19.7 0.0 1.8 403.9 15.9 1.3 0.9 0.0 0.6 18.7 0.0 0.6 AR "AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1" ENSG00000169083 "Androgen receptor" P10275 X 67544021-67730619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 93.7;Granulosa cells: 104.8;Hepatocytes: 269.2;Leydig cells: 77.9;Peritubular cells: 86.5;Skeletal myocytes: 75.0" "Cancer enhanced" "Detected in many" "breast cancer: 15.6;prostate cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.3;BJ hTERT+: 10.3;HAP1: 14.9;LHCN-M2: 16.1;RH-30: 23.6;T-47d: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000001, HPA004733, CAB065764" Enhanced Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 35: Glandular cells - Unknown function" Cytosol "CAB000001: AB_2060174, CAB065764: AB_10620739, HPA004733: " "unprognostic (1.34e-1)" "unprognostic (8.10e-3)" "unprognostic (2.49e-2)" "unprognostic (5.95e-2)" "unprognostic (1.04e-2)" "unprognostic (3.35e-2)" "prognostic favorable (8.77e-4)" "unprognostic (4.99e-2)" "unprognostic (1.72e-1)" "unprognostic (7.79e-2)" "unprognostic (2.30e-1)" "unprognostic (2.29e-1)" "prognostic favorable (1.03e-8)" "unprognostic (8.23e-3)" "unprognostic (8.90e-2)" "unprognostic (4.23e-2)" "unprognostic (7.97e-2)" 6.7 1.0 1.1 0.5 1.3 0.0 8.7 1.7 1.1 23.6 0.2 2.0 0.2 18.6 16.1 1.2 20.7 2.0 5.8 1.0 3.5 3.6 38.2 1.5 0.3 3.5 2.6 14.6 0.8 0.1 1.9 0.1 2.7 16.5 0.6 0.2 1.4 18.2 13.9 5.2 0.9 9.5 2.1 1.3 1.5 3.9 4.8 2.7 2.1 6.1 0.5 3.5 12.9 2.0 0.0 4.8 13.3 0.0 0.0 0.0 0.0 7.3 10.3 0.3 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.0 14.9 0.0 0.0 0.0 2.4 0.0 1.5 0.0 0.8 0.0 0.0 5.5 0.0 1.8 0.0 0.0 3.9 0.1 4.6 2.2 16.1 1.5 0.0 0.0 5.4 0.0 0.0 0.0 23.6 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 3.6 10.9 7.6 0.3 0.3 2.2 0.0 3.5 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.7 1.1 1.0 3.5 3.5 2.6 2.7 2.1 4.8 2.0 3.1 0.0 5.0 28.4 0.4 9.7 17.8 0.2 15.9 0.7 93.7 33.7 37.4 14.3 10.7 3.7 0.0 3.5 14.0 0.0 1.9 11.3 1.1 2.9 49.1 10.5 0.0 5.3 7.7 0.0 0.2 39.4 0.0 5.8 1.3 104.8 36.0 269.2 0.8 0.0 17.8 0.3 0.0 2.2 4.2 4.4 77.9 3.3 10.6 1.0 1.7 0.2 0.0 26.7 0.2 0.6 0.0 86.5 0.0 36.5 0.6 27.7 3.6 0.3 65.7 75.0 20.8 0.8 3.3 12.7 16.1 1.0 1.7 37.8 0.2 22.0 ARAF ARAF1 ENSG00000078061 "A-Raf proto-oncogene, serine/threonine kinase" P10398 X 47561205-47571908 "Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066326 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA066326: AB_2685659" "unprognostic (1.21e-1)" "unprognostic (5.69e-3)" "unprognostic (2.47e-2)" "unprognostic (2.10e-2)" "unprognostic (7.63e-2)" "unprognostic (9.35e-2)" "unprognostic (1.79e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-2)" "unprognostic (1.61e-1)" "unprognostic (6.75e-2)" "unprognostic (8.65e-2)" "prognostic favorable (1.45e-6)" "unprognostic (1.97e-1)" "unprognostic (2.01e-1)" "unprognostic (6.37e-2)" "unprognostic (4.71e-2)" 37.7 41.7 17.8 36.9 20.8 102.3 36.2 19.2 21.1 34.8 22.6 40.9 37.8 36.6 21.2 32.2 35.0 32.5 50.8 17.1 18.0 44.6 55.7 39.4 40.4 22.8 20.5 39.5 59.1 51.8 27.7 31.3 20.1 40.9 33.3 15.4 45.1 34.6 136.3 36.0 39.7 31.3 18.8 46.1 46.7 12.0 21.0 38.0 39.4 85.6 31.5 36.1 30.8 20.4 49.1 69.5 29.2 46.9 43.5 34.2 39.0 40.3 42.3 58.6 54.1 57.2 58.6 29.0 32.4 54.6 49.2 67.3 51.8 56.3 34.3 53.5 61.9 29.4 74.4 30.6 61.4 58.3 85.1 45.0 56.0 56.2 49.6 39.2 45.9 36.0 55.2 55.7 40.5 83.3 42.6 64.0 41.8 41.2 77.8 39.2 38.0 65.5 34.4 46.7 32.8 25.0 43.7 39.7 24.5 47.0 74.9 43.3 44.2 38.0 42.5 76.2 41.4 71.1 49.2 22.5 50.8 65.3 31.1 48.3 47.8 61.3 44.1 57.8 40.3 32.6 38.4 40.9 55.2 37.3 33.5 40.5 37.8 38.7 67.9 40.4 41.6 50.8 17.8 20.8 19.2 21.1 17.1 18.0 22.8 20.5 20.1 18.8 21.0 20.4 13.3 16.0 29.2 7.5 25.8 15.7 25.0 29.0 18.2 5.3 15.0 9.8 25.1 34.3 22.0 18.4 10.4 33.0 26.3 43.8 23.5 29.3 1.3 11.4 10.8 17.5 31.8 22.3 5.0 34.3 30.4 16.9 39.3 15.6 16.5 13.6 24.3 42.6 28.0 13.5 5.5 35.9 40.7 26.4 21.6 4.3 17.4 25.8 33.8 4.7 43.7 18.4 32.0 8.5 8.9 26.2 41.5 17.7 27.9 20.3 44.6 27.1 11.5 9.0 19.7 15.9 18.0 8.2 10.5 17.7 16.2 44.6 26.5 12.5 32.3 24.6 ARCN1 COPD ENSG00000095139 "Archain 1" P48444 11 118572390-118603033 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037573, HPA044874" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 140000 "Cluster 18: Basophils - Vesicular transport" "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Golgi apparatus, Cytosol" "HPA037573: AB_10696938, HPA044874: AB_2679126" "unprognostic (1.46e-2)" "unprognostic (4.97e-2)" "unprognostic (1.66e-1)" "unprognostic (3.20e-1)" "unprognostic (9.99e-2)" "unprognostic (2.30e-2)" "prognostic unfavorable (2.97e-5)" "unprognostic (3.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-3)" "unprognostic (9.39e-2)" "unprognostic (3.56e-2)" "unprognostic (7.99e-2)" "unprognostic (9.20e-2)" "unprognostic (4.14e-3)" "unprognostic (5.56e-3)" 75.4 67.7 47.5 53.8 51.0 30.4 67.5 52.0 60.5 78.0 61.2 65.0 59.2 69.2 111.1 72.5 60.5 51.6 75.6 46.8 50.9 58.3 91.6 62.6 53.2 51.2 51.3 65.5 119.7 61.9 88.7 54.7 51.1 68.8 67.1 39.2 79.6 64.5 51.1 60.9 64.9 71.0 50.0 57.9 71.8 46.2 50.5 58.8 65.2 55.0 62.2 66.4 60.9 57.2 90.9 72.6 135.3 98.9 174.0 172.7 66.6 244.8 208.5 102.4 120.7 239.4 116.6 96.4 199.7 275.7 148.0 123.7 160.5 139.5 151.5 128.0 66.3 211.6 56.7 151.4 197.1 140.4 121.8 157.8 117.6 175.0 168.7 149.3 162.2 95.0 106.8 139.2 201.3 157.0 123.2 130.8 85.3 207.7 92.4 107.9 134.2 147.4 137.3 107.0 88.3 86.6 130.2 129.0 70.1 132.5 155.9 111.4 144.0 129.4 65.1 118.4 109.5 79.9 78.5 147.6 74.3 122.6 161.4 118.1 49.8 50.7 52.7 59.8 69.0 39.5 51.7 51.3 54.0 35.4 48.0 44.7 41.5 64.5 64.5 44.9 53.9 55.8 47.5 51.0 52.0 60.5 46.8 50.9 51.2 51.3 51.1 50.0 50.5 57.2 43.6 35.3 47.9 12.4 32.2 31.6 38.5 31.5 23.9 22.4 39.4 27.9 46.5 24.3 41.9 31.3 4.2 17.2 45.6 68.4 9.8 34.3 11.1 38.4 72.2 43.1 40.2 14.9 15.4 37.8 36.1 44.9 39.3 50.4 39.3 31.9 31.4 55.7 30.3 18.5 17.7 80.2 22.4 36.0 37.6 8.5 48.1 35.3 23.2 11.2 49.0 17.3 26.8 17.1 20.2 46.9 35.8 41.3 68.3 51.5 56.2 30.5 46.2 13.6 19.7 52.7 45.7 44.8 47.6 30.4 34.7 30.2 38.4 43.9 42.6 51.6 ARFGEF2 BIG2 ENSG00000124198 "ADP ribosylation factor guanine nucleotide exchange factor 2" Q9Y6D5 20 48921711-49036693 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 81.5" "Cell type enhanced" "Detected in all" "Excitatory neurons: 102.6;Inhibitory neurons: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026078, CAB026382" Supported Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Vesicles, Cytosol" "CAB026382: , HPA026078: AB_1844983" "unprognostic (1.50e-2)" "unprognostic (9.56e-3)" "unprognostic (4.14e-2)" "unprognostic (4.94e-3)" "unprognostic (5.30e-2)" "unprognostic (6.94e-2)" "unprognostic (1.57e-2)" "unprognostic (2.99e-1)" "unprognostic (8.47e-2)" "unprognostic (1.34e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "prognostic favorable (6.15e-7)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (2.85e-1)" "unprognostic (3.90e-2)" 9.1 20.2 2.8 8.7 4.1 10.4 15.8 1.9 5.8 11.5 7.9 14.2 13.7 9.0 5.9 11.0 7.5 8.5 13.4 4.5 3.9 15.3 12.4 7.8 9.8 2.6 3.2 7.7 19.2 81.5 8.7 9.2 3.5 10.6 15.7 6.8 11.0 9.7 11.8 11.1 10.9 9.5 1.9 10.4 16.2 13.6 3.5 11.3 23.8 18.2 14.2 11.1 8.2 5.0 18.3 16.5 8.9 5.1 18.0 14.8 21.8 15.5 19.5 36.6 19.0 37.1 19.8 25.5 22.1 19.7 33.8 21.0 18.6 23.6 33.8 9.0 7.6 17.5 17.9 25.4 19.7 22.6 19.7 15.0 21.6 23.9 27.6 12.7 28.4 11.7 15.0 22.3 20.8 6.3 13.0 6.8 8.3 20.5 17.4 14.0 25.5 30.3 13.6 23.4 7.1 9.0 42.6 66.0 23.4 10.3 26.6 18.6 34.5 35.6 16.5 18.2 13.1 35.9 35.0 18.7 23.4 10.7 11.6 1.1 0.6 0.2 0.5 0.4 0.6 0.5 0.5 0.4 0.7 0.9 0.8 0.7 0.3 0.3 0.3 0.9 0.1 0.3 2.8 4.1 1.9 5.8 4.5 3.9 2.6 3.2 3.5 1.9 3.5 5.0 16.6 19.2 26.0 37.2 21.2 11.3 12.2 11.0 11.4 15.3 27.7 14.7 40.7 17.2 20.0 11.0 14.6 10.5 14.7 30.4 1.9 10.9 16.6 19.5 17.1 19.5 12.5 14.3 102.6 13.3 10.0 12.6 16.3 24.7 15.2 11.0 20.7 27.8 10.8 11.8 96.7 23.3 8.2 15.7 13.9 24.6 10.2 17.8 10.6 60.9 15.6 5.4 10.3 43.2 57.0 15.5 21.6 11.3 29.0 24.1 18.6 11.5 17.2 16.1 6.6 14.2 12.5 32.6 20.4 17.5 15.5 30.0 13.2 16.6 21.0 21.2 ARHGAP31 CDGAP ENSG00000031081 "Rho GTPase activating protein 31" Q2M1Z3 3 119294383-119420714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.8;Astrocytes: 123.1;Endothelial cells: 46.9;Langerhans cells: 54.1;Microglial cells: 125.5;Oligodendrocyte precursor cells: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 6.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 35.0;TIME: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036380 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA036380: AB_10673129" "unprognostic (2.22e-2)" "unprognostic (1.93e-2)" "unprognostic (9.90e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-2)" "unprognostic (1.11e-1)" "unprognostic (8.75e-3)" "unprognostic (3.22e-2)" "unprognostic (2.57e-1)" "unprognostic (7.18e-3)" "unprognostic (5.86e-2)" "unprognostic (1.30e-1)" "prognostic favorable (8.45e-4)" "unprognostic (3.57e-2)" "unprognostic (6.32e-2)" "unprognostic (1.38e-1)" "unprognostic (7.79e-3)" 17.0 2.1 8.3 7.6 9.3 0.8 9.0 10.1 8.3 6.0 1.1 5.4 3.0 6.2 3.1 5.9 5.1 8.6 13.0 8.3 8.9 4.9 3.6 19.5 5.6 11.6 10.4 6.1 2.9 4.0 2.1 11.2 9.4 3.0 5.4 1.5 2.8 3.4 4.2 6.4 4.7 11.8 9.0 7.1 3.2 1.3 10.8 6.9 12.7 9.2 6.8 8.1 3.8 9.9 0.4 2.5 6.2 12.2 3.5 2.9 1.9 7.5 8.6 5.8 4.2 0.1 0.5 0.1 8.7 19.5 10.0 0.2 5.9 1.9 6.7 11.0 0.8 1.7 0.8 0.0 5.8 0.4 7.0 7.8 0.2 15.1 1.7 4.5 35.0 1.2 0.0 3.0 13.1 0.2 0.1 0.3 2.1 0.0 7.6 0.0 2.9 0.0 1.7 0.0 0.0 22.7 3.8 0.0 15.6 3.3 0.7 0.6 38.5 16.0 6.4 2.0 5.9 5.1 5.6 6.2 10.9 5.6 16.4 0.0 2.6 0.0 0.4 2.8 0.8 1.6 0.3 0.5 6.0 0.6 0.3 0.2 0.0 1.1 1.1 5.2 0.8 1.2 8.3 9.3 10.1 8.3 8.3 8.9 11.6 10.4 9.4 9.0 10.8 9.9 47.8 19.2 24.6 123.1 7.3 5.2 0.7 3.1 1.8 0.6 0.5 1.7 16.0 1.5 3.1 0.0 0.0 1.2 9.8 0.2 0.0 2.1 0.4 0.4 2.1 46.9 0.0 7.4 3.4 2.0 10.3 7.3 0.0 0.4 9.5 8.4 30.7 0.6 10.1 0.0 18.4 3.9 0.0 14.5 54.1 0.7 2.8 16.7 10.6 125.5 13.8 3.9 4.1 159.8 0.9 1.9 0.3 2.6 4.9 1.1 0.0 2.1 1.4 0.4 0.0 2.5 11.3 0.3 0.7 1.3 5.1 1.0 3.7 3.3 0.4 0.7 ARHGEF2 "GEF-H1, GEFH1, KIAA0651, Lfc, LFP40, P40" ENSG00000116584 "Rho/Rac guanine nucleotide exchange factor 2" Q92974 1 155946851-156007070 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Mitosis, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043437 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 3: Monocytes - Immune response regulation" "HPA043437: AB_2678481" "unprognostic (2.27e-2)" "unprognostic (8.30e-3)" "unprognostic (3.24e-3)" "unprognostic (1.90e-3)" "unprognostic (4.14e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (9.20e-6)" "unprognostic (5.96e-2)" "unprognostic (2.14e-1)" "unprognostic (3.62e-2)" "unprognostic (2.59e-1)" "unprognostic (3.92e-1)" "prognostic unfavorable (7.17e-6)" "unprognostic (4.63e-2)" "unprognostic (2.70e-1)" "unprognostic (8.85e-3)" "unprognostic (7.98e-2)" 48.9 12.3 52.6 39.2 80.8 64.0 40.8 69.0 77.8 38.8 18.7 47.3 18.8 37.0 15.2 25.8 42.1 31.1 42.8 55.5 56.2 35.7 13.2 89.9 48.4 85.9 75.9 28.1 15.1 18.5 16.8 32.1 84.1 27.3 28.8 11.1 25.0 15.1 17.8 17.9 45.4 29.9 60.9 69.9 39.9 33.9 77.2 38.6 46.7 16.8 32.6 37.8 31.4 130.6 32.0 25.7 44.0 30.3 41.4 51.9 45.3 69.9 89.4 67.2 71.5 23.3 23.6 79.4 41.9 53.8 35.4 45.7 26.7 22.2 50.9 32.5 22.9 105.1 40.9 14.0 162.4 138.6 87.8 61.1 90.4 100.2 122.1 50.7 55.7 60.5 59.2 94.2 96.2 17.7 70.2 187.2 48.8 53.4 17.0 75.5 61.3 135.9 28.3 19.0 72.1 33.1 30.1 43.6 246.1 43.6 45.0 188.7 73.6 57.7 32.7 50.9 89.8 155.7 171.1 55.6 82.4 68.7 144.6 15.1 20.6 17.1 15.7 18.1 10.8 14.6 9.9 11.3 18.2 13.1 9.6 11.0 31.7 11.0 21.9 8.7 9.9 28.2 52.6 80.8 69.0 77.8 55.5 56.2 85.9 75.9 84.1 60.9 77.2 130.6 26.4 38.5 73.4 2.9 43.9 15.2 28.1 12.6 10.8 54.1 15.7 12.3 6.2 10.0 12.0 16.5 2.1 3.5 32.1 21.1 7.9 15.5 52.9 6.6 10.2 32.3 30.5 48.6 30.8 5.3 22.8 24.8 59.1 13.3 27.9 8.9 23.2 1.0 29.7 1.7 17.0 20.9 16.2 49.0 67.8 16.1 11.5 46.0 24.9 20.6 82.9 12.9 48.4 22.1 105.5 16.5 22.5 10.1 20.0 16.7 9.8 2.2 13.0 3.3 59.2 32.9 30.8 3.1 4.1 11.7 13.8 3.4 29.7 2.1 14.2 40.2 ARID1A "B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1" ENSG00000117713 "AT-rich interaction domain 1A" O14497 1 26693236-26782104 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005456, CAB016334" Supported Enhanced Nucleoplasm NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB016334: AB_673396, HPA005456: AB_1078205" "unprognostic (2.83e-1)" "unprognostic (1.81e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (4.18e-4)" "unprognostic (3.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" "unprognostic (7.76e-2)" "unprognostic (1.01e-2)" "unprognostic (1.62e-2)" "unprognostic (6.05e-2)" "unprognostic (2.66e-1)" "unprognostic (6.54e-2)" 16.4 16.3 10.1 22.7 9.4 37.0 16.4 12.9 24.3 16.2 0.0 18.0 15.4 20.4 15.8 22.2 18.3 14.0 17.4 6.3 35.8 13.3 16.8 16.8 25.8 20.8 6.8 20.8 23.2 19.3 14.3 18.6 9.9 15.1 15.3 20.1 19.3 14.4 21.6 20.5 20.3 17.5 3.0 24.3 19.5 16.7 17.9 46.4 22.6 17.6 23.7 18.4 17.8 9.0 53.2 49.5 68.6 71.5 19.6 18.5 32.3 24.4 21.1 32.7 23.0 36.3 34.1 74.3 20.7 31.8 20.7 31.6 60.3 26.9 37.9 92.7 22.6 63.6 33.0 24.7 16.1 95.2 19.6 21.7 18.8 38.7 27.5 18.2 28.6 52.5 77.7 81.1 21.5 25.1 80.1 36.8 72.4 34.5 22.9 82.2 45.3 42.1 20.3 35.3 62.9 50.7 42.7 35.7 29.0 37.8 10.6 53.4 50.6 34.9 33.5 32.4 39.9 38.0 54.9 34.1 21.2 59.8 31.5 0.2 1.5 1.5 1.6 1.2 2.1 1.8 1.3 2.1 1.4 1.6 1.7 1.9 3.3 2.1 1.3 2.4 0.7 1.9 10.1 9.4 12.9 24.3 6.3 35.8 20.8 6.8 9.9 3.0 17.9 9.0 49.9 60.9 40.4 99.9 66.6 73.4 21.0 32.5 90.0 68.0 77.2 61.5 33.0 38.6 35.9 38.6 52.1 36.5 56.1 46.5 1.9 35.3 23.3 48.8 59.3 46.3 47.5 56.6 47.1 37.6 40.2 35.9 35.7 72.3 61.2 68.4 49.6 65.6 51.0 74.0 59.8 50.2 28.5 89.0 47.5 9.0 38.5 73.2 40.9 89.9 86.4 30.8 53.5 78.9 116.1 49.7 36.4 41.8 48.5 50.0 32.4 16.7 36.1 42.3 52.6 38.2 47.3 44.1 52.2 101.8 94.3 36.7 57.0 45.8 52.1 43.2 ARID1B "6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R" ENSG00000049618 "AT-rich interaction domain 1B" Q8NFD5 6 156776020-157210779 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 404.3;Inhibitory neurons: 475.4;Microglial cells: 327.0;Oligodendrocyte precursor cells: 417.7;Oligodendrocytes: 503.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016511, HPA075291" Approved Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA016511: AB_1845008, HPA075291: AB_2686743" "prognostic unfavorable (1.04e-4)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (5.42e-2)" "unprognostic (7.47e-2)" "unprognostic (1.40e-2)" "unprognostic (2.73e-2)" "unprognostic (2.89e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.16e-4)" "unprognostic (2.53e-1)" "unprognostic (5.33e-2)" "unprognostic (1.07e-3)" "unprognostic (2.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.53e-1)" "unprognostic (1.16e-1)" 15.2 12.0 14.6 14.5 13.4 28.7 15.6 29.0 16.0 19.0 2.2 15.9 14.2 17.0 11.3 15.7 18.6 14.4 14.4 20.4 10.1 13.2 9.7 14.6 18.2 13.4 10.9 27.5 17.1 28.2 12.2 11.7 11.1 14.6 12.1 11.7 20.4 12.7 33.6 23.2 15.3 15.8 7.3 18.4 12.5 9.8 12.5 25.4 22.0 25.4 18.8 17.4 17.4 17.2 13.0 19.4 29.6 41.2 24.7 21.5 20.4 14.6 18.6 18.1 18.0 17.7 20.0 43.0 8.1 23.9 22.4 16.5 25.2 23.3 18.1 40.4 18.1 30.6 19.6 22.1 17.1 25.3 21.8 25.5 18.4 27.1 24.6 20.4 25.6 26.8 35.8 32.3 13.2 15.9 29.1 30.5 15.3 18.3 10.5 66.3 12.7 22.9 12.7 24.3 28.0 34.7 28.3 29.4 15.8 15.7 19.6 40.2 26.4 23.4 23.6 22.0 27.5 21.8 18.2 52.7 19.7 30.3 32.0 5.0 2.3 2.3 4.1 1.9 3.7 5.3 3.5 2.8 1.8 6.9 2.9 4.1 4.2 2.4 2.1 9.4 3.7 1.2 14.6 13.4 29.0 16.0 20.4 10.1 13.4 10.9 11.1 7.3 12.5 17.2 85.7 48.1 51.8 282.7 83.3 47.5 22.3 22.3 41.5 36.0 70.9 44.4 36.9 27.1 32.6 126.9 29.2 14.7 103.7 21.8 7.9 40.8 15.0 70.8 124.5 43.9 40.8 37.8 404.3 34.5 7.5 49.9 31.1 78.0 38.7 137.1 33.9 27.3 14.1 47.1 475.4 33.7 20.3 32.6 36.1 19.4 56.8 49.1 30.2 327.0 59.4 21.9 24.7 417.7 503.7 46.6 26.9 62.8 70.2 28.1 26.8 18.4 29.5 29.6 46.0 43.1 56.7 8.0 12.2 39.7 55.7 17.5 51.9 72.9 36.3 27.1 ARID2 "BAF200, DKFZp686G052, FLJ30619, KIAA1557" ENSG00000189079 "AT-rich interaction domain 2" Q68CP9 12 45729706-45908040 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 525.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063044 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA063044: AB_2684929" "unprognostic (8.41e-2)" "unprognostic (1.03e-1)" "unprognostic (4.02e-2)" "unprognostic (3.94e-2)" "unprognostic (4.15e-2)" "prognostic favorable (5.75e-4)" "unprognostic (1.26e-2)" "unprognostic (9.71e-2)" "unprognostic (9.04e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.47e-1)" "unprognostic (1.12e-2)" "unprognostic (9.21e-2)" "unprognostic (3.02e-1)" "unprognostic (2.00e-1)" "unprognostic (6.53e-2)" 6.4 5.2 4.6 6.7 7.8 12.6 7.5 13.8 6.9 8.5 10.2 6.8 5.0 6.9 6.5 8.4 6.4 5.4 6.0 5.0 7.3 6.3 5.4 7.8 7.5 7.8 6.4 8.3 7.2 11.7 5.0 7.2 7.6 7.4 6.0 13.2 6.7 6.2 5.9 10.0 6.6 6.1 6.0 6.9 6.2 26.1 6.2 18.7 8.8 7.7 8.9 6.8 8.0 9.8 10.3 14.5 25.3 11.1 10.5 7.3 13.7 7.0 9.9 9.6 8.9 20.7 10.4 19.8 12.7 9.8 7.0 12.1 20.6 11.8 13.6 8.8 9.8 26.1 15.9 10.1 7.2 20.7 11.5 6.0 8.8 12.1 19.1 13.4 10.0 29.1 22.4 19.9 8.6 13.4 29.9 14.7 15.1 0.0 7.7 22.9 18.0 19.0 9.1 16.9 13.6 17.4 11.4 13.0 11.1 14.5 20.0 40.8 11.8 10.3 12.3 7.0 9.2 13.2 11.8 53.6 7.9 53.2 7.4 9.4 1.1 2.7 2.4 1.3 2.5 1.0 2.1 2.5 1.5 1.1 2.0 1.9 1.4 2.1 3.4 3.3 2.0 0.9 4.6 7.8 13.8 6.9 5.0 7.3 7.8 6.4 7.6 6.0 6.2 9.8 23.3 28.9 28.4 110.4 30.8 33.8 14.4 16.3 36.5 51.6 21.7 15.4 15.6 14.3 17.3 29.5 68.8 15.5 49.0 21.3 7.9 13.2 525.4 23.2 23.8 21.1 21.0 35.1 56.7 10.0 10.5 22.0 24.5 27.7 22.1 29.3 19.2 17.3 11.2 32.0 60.3 19.0 22.4 29.8 36.7 149.3 24.8 25.6 14.2 128.4 22.4 19.9 45.3 144.3 157.9 18.8 24.6 22.6 33.8 23.7 19.1 7.4 15.4 66.2 26.3 27.0 27.2 80.2 17.0 39.3 41.3 23.4 34.8 16.4 17.9 21.0 ARL13B "ARL2L1, DKFZp761H079, JBTS8" ENSG00000169379 "ADP ribosylation factor like GTPase 13B" Q3SXY8 3 93980139-94055678 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 18.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 93.0;Rod photoreceptor cells: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048926 Approved Uncertain Microtubules,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 46: Photoreceptor cells - Phototransduction" Microtubules Cytosol "HPA048926: AB_2680559" "unprognostic (2.29e-2)" "unprognostic (2.35e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (1.94e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-2)" "unprognostic (2.97e-1)" "unprognostic (1.05e-2)" "unprognostic (1.19e-1)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (5.42e-3)" "unprognostic (8.86e-2)" "unprognostic (2.73e-1)" "unprognostic (5.41e-2)" "unprognostic (7.50e-2)" 3.4 2.5 1.3 2.9 1.6 0.8 2.3 1.2 2.5 4.1 8.7 1.9 0.8 4.6 1.0 3.3 4.1 4.0 2.0 1.2 1.1 3.6 2.6 4.1 2.1 1.5 1.8 3.2 1.5 3.6 2.0 2.7 1.6 2.0 1.4 18.2 1.5 2.6 0.7 1.4 1.9 4.2 1.5 2.9 1.6 3.5 1.2 2.5 4.3 1.7 1.7 3.1 1.7 2.0 8.3 12.5 7.9 4.3 13.3 3.5 3.6 7.8 4.8 11.8 15.9 8.0 4.4 5.9 11.3 6.9 7.1 5.1 7.2 5.3 16.2 10.5 6.4 12.7 5.6 5.4 6.0 15.2 6.9 5.2 2.1 12.3 19.0 4.5 4.0 8.7 12.5 7.3 6.7 3.1 12.3 1.2 2.9 4.3 7.5 7.2 25.8 2.0 5.7 1.2 18.0 4.6 15.9 0.9 9.4 2.9 2.1 3.5 7.7 11.6 11.0 6.8 9.6 1.8 2.0 11.7 8.5 8.8 8.5 6.4 3.4 2.9 3.7 4.2 3.8 3.9 3.3 3.0 3.0 3.4 3.3 3.1 2.0 4.3 4.8 4.8 2.9 1.8 1.3 1.6 1.2 2.5 1.2 1.1 1.5 1.8 1.6 1.5 1.2 2.0 27.2 93.0 39.6 31.6 11.3 46.8 28.1 8.6 10.2 19.0 11.0 16.8 8.1 12.8 19.7 1.8 41.7 1.9 7.1 1.3 15.6 17.1 14.8 30.1 25.2 31.7 22.1 6.5 58.4 11.8 6.3 48.5 10.2 11.2 45.6 9.2 17.5 7.7 12.1 15.2 41.5 3.1 12.2 7.0 21.6 6.4 23.9 10.7 16.0 38.4 6.0 26.9 6.2 29.7 49.8 11.4 3.8 25.6 8.0 13.9 1.8 18.7 71.9 102.0 6.6 59.4 33.8 43.1 14.5 12.7 58.7 0.8 13.2 16.5 3.1 10.6 ARL3 ARFL3 ENSG00000138175 "ADP ribosylation factor like GTPase 3" P36405 10 102673731-102714397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 96.3" "Cell type enhanced" "Detected in all" "Muller glia cells: 289.1;Rod photoreceptor cells: 318.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036292, HPA063596" Approved Supported Nucleoplasm,Centrosome NA NA 44000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 6: T47d - Mammary gland" "Cluster 46: Photoreceptor cells - Phototransduction" Centrosome Nucleoplasm "HPA036292: AB_10673618, HPA063596: AB_2685053" "unprognostic (1.36e-1)" "unprognostic (2.89e-3)" "unprognostic (4.19e-2)" "unprognostic (7.58e-2)" "unprognostic (2.98e-2)" "unprognostic (3.24e-2)" "unprognostic (2.45e-2)" "unprognostic (7.69e-2)" "unprognostic (4.00e-2)" "unprognostic (3.21e-1)" "unprognostic (3.99e-3)" "unprognostic (5.58e-2)" "prognostic favorable (1.71e-6)" "unprognostic (5.62e-2)" "unprognostic (3.09e-2)" "unprognostic (4.21e-2)" "unprognostic (1.03e-1)" 8.1 8.9 20.2 4.2 21.3 1.7 8.1 20.8 25.1 12.4 19.1 11.3 4.2 11.5 10.6 4.6 15.2 5.2 13.5 20.8 19.5 15.4 5.2 8.3 3.6 19.3 19.1 16.8 6.4 19.8 21.0 4.9 19.7 8.7 4.6 96.3 6.3 9.0 5.6 7.2 6.1 8.7 18.5 4.5 8.8 11.0 20.5 5.7 11.4 5.9 4.7 9.8 8.3 19.5 14.7 25.0 33.6 24.7 15.2 22.7 5.9 11.4 17.3 13.6 14.7 8.7 7.4 6.1 10.8 18.5 16.4 10.7 12.7 15.3 16.9 16.1 13.4 9.9 16.9 8.3 16.4 4.6 9.5 11.5 12.6 18.8 11.0 36.1 15.8 12.0 4.5 6.0 23.0 15.1 9.5 7.3 13.0 9.2 9.8 7.9 24.8 5.4 18.1 7.7 11.8 25.7 8.7 1.8 14.1 18.5 45.1 4.6 9.1 9.2 12.9 18.9 16.0 4.2 8.9 11.3 24.4 13.6 8.1 2.0 7.2 2.6 3.7 6.1 9.4 4.5 6.5 5.5 7.1 3.9 3.9 4.7 13.4 4.4 5.4 5.2 4.9 5.4 20.2 21.3 20.8 25.1 20.8 19.5 19.3 19.1 19.7 18.5 20.5 19.5 46.0 54.5 39.3 47.7 16.7 32.1 70.4 144.3 29.0 167.6 48.2 57.5 135.5 31.5 85.8 62.5 116.7 45.5 12.1 9.4 234.8 70.7 46.5 250.5 85.2 41.6 74.8 9.4 30.8 43.6 37.8 61.7 19.4 84.6 33.0 94.1 43.9 25.5 64.7 97.6 37.6 31.6 73.2 16.4 33.6 25.8 60.6 26.8 76.5 13.1 67.3 289.1 13.4 31.7 23.4 31.1 13.5 104.2 18.6 54.2 23.1 225.8 268.3 318.6 26.3 50.8 122.0 145.6 43.4 11.9 31.7 32.3 20.8 58.6 25.4 50.5 ARMC9 "ARM, FLJ12584, KIAA1868, KU-MEL-1" ENSG00000135931 "Armadillo repeat containing 9" Q7Z3E5 2 231198546-231376848 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 48.6;retina: 71.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 310.6;Excitatory neurons: 112.5;monocytes: 116.4;Rod photoreceptor cells: 202.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 15.5" "Immune cell enhanced" "Detected in some" "NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 275.2;SK-MEL-30: 222.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019041, HPA026671" Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA019041: AB_1845035, HPA026671: AB_1845036" "unprognostic (2.90e-1)" "unprognostic (2.86e-1)" "unprognostic (5.35e-2)" "unprognostic (6.26e-2)" "unprognostic (1.99e-2)" "unprognostic (5.57e-2)" "unprognostic (7.20e-4)" "unprognostic (1.58e-2)" "unprognostic (4.85e-2)" "unprognostic (7.17e-3)" "unprognostic (4.14e-1)" "unprognostic (9.15e-2)" "unprognostic (7.43e-2)" "unprognostic (1.30e-2)" "unprognostic (4.19e-2)" "unprognostic (5.57e-2)" "prognostic unfavorable (7.66e-5)" 2.3 15.0 4.0 5.4 5.3 1.9 3.3 1.1 15.5 5.6 48.6 14.7 1.7 19.5 5.6 4.2 8.7 7.7 2.3 5.9 1.9 5.2 0.8 7.1 1.6 0.4 2.4 9.4 3.7 10.8 11.1 5.7 0.1 5.5 5.2 71.5 3.2 6.6 1.0 2.6 6.5 23.5 0.0 1.1 8.9 9.4 0.2 3.0 7.6 1.1 2.1 6.8 2.7 1.7 21.2 10.8 20.3 15.1 14.5 23.7 8.3 23.3 275.2 28.6 35.8 3.1 10.3 2.7 11.0 68.3 46.6 12.2 24.8 22.7 25.0 1.7 15.2 1.5 14.0 11.6 41.3 5.0 5.1 63.8 8.8 38.3 13.7 73.3 21.7 12.2 4.7 0.6 46.0 29.9 6.3 6.9 44.4 7.7 12.0 7.8 18.2 0.3 30.6 6.9 15.6 32.2 9.3 25.2 222.7 17.8 9.7 5.4 22.6 17.6 10.9 10.0 10.4 24.8 6.2 1.3 33.9 1.0 17.7 1.1 0.2 0.3 0.2 0.1 0.1 0.6 0.2 0.3 0.2 0.3 0.3 0.3 0.5 2.6 0.2 0.3 0.2 0.2 4.0 5.3 1.1 15.5 5.9 1.9 0.4 2.4 0.1 0.0 0.2 1.7 1.3 3.2 36.1 25.8 1.4 1.8 5.6 6.8 1.2 24.0 5.1 5.7 3.3 2.8 7.5 3.7 310.6 4.8 0.1 4.0 1.9 7.3 69.5 25.1 22.3 4.9 7.8 1.3 112.5 17.3 3.0 7.2 3.6 4.1 3.8 6.6 2.5 1.0 10.6 1.7 62.7 6.0 0.0 0.3 2.4 23.8 14.0 6.6 19.6 17.8 116.4 16.7 1.0 25.6 14.1 11.5 1.8 21.4 1.1 1.9 0.7 5.1 31.3 202.4 6.6 5.3 6.4 36.7 15.7 0.6 0.9 2.2 1.3 6.3 10.0 2.1 ARNT2 "bHLHe1, KIAA0307" ENSG00000172379 "Aryl hydrocarbon receptor nuclear translocator 2" Q9HBZ2 15 80404350-80597933 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 128.0" "Group enriched" "Detected in many" 4 "Astrocytes: 209.6;Excitatory neurons: 204.7;Inhibitory neurons: 301.5;Microglial cells: 98.4;Oligodendrocyte precursor cells: 232.7;Oligodendrocytes: 136.9" "Cancer enhanced" "Detected in all" "glioma: 27.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 28.4;BJ hTERT+ SV40 Large T+ RasG12V: 28.2;hTERT-RPE1: 29.7;LHCN-M2: 26.0;SK-MEL-30: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001056, CAB005081" Enhanced Supported Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB005081: AB_2243005, HPA001056: AB_1845042" "unprognostic (2.04e-3)" "unprognostic (8.32e-2)" "unprognostic (2.10e-1)" "unprognostic (1.95e-1)" "unprognostic (1.11e-1)" "unprognostic (5.65e-2)" "unprognostic (2.61e-2)" "unprognostic (1.48e-1)" "unprognostic (2.74e-2)" "unprognostic (3.00e-1)" "prognostic favorable (1.46e-6)" "unprognostic (2.20e-1)" "prognostic favorable (7.51e-4)" "unprognostic (2.53e-1)" "unprognostic (2.31e-1)" "unprognostic (3.39e-1)" "unprognostic (3.62e-2)" 2.2 2.1 94.4 2.1 100.6 0.4 1.4 47.8 111.7 5.6 29.8 5.8 1.7 5.9 8.2 2.0 5.3 2.5 4.1 128.0 64.2 21.7 0.4 5.0 2.3 61.8 70.5 10.7 3.4 6.4 11.5 1.1 53.6 5.5 2.1 8.1 1.2 5.0 9.7 2.1 2.7 3.9 60.2 3.5 4.1 9.9 84.0 2.2 7.0 6.0 3.0 4.3 2.0 66.7 0.4 16.1 28.4 0.0 0.1 3.6 0.1 12.2 17.3 13.9 28.2 0.0 0.0 0.0 3.0 14.7 7.2 0.4 10.5 0.6 17.7 0.0 2.9 0.5 0.0 1.0 0.9 0.0 7.2 13.2 0.5 6.1 0.3 29.7 0.0 0.0 0.0 0.1 26.0 14.0 0.0 0.0 5.7 0.0 0.2 0.0 0.3 0.0 6.0 20.5 14.9 20.6 1.5 0.2 30.8 1.8 0.6 0.0 0.0 22.2 4.4 0.6 14.7 0.0 0.0 0.0 8.4 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.4 100.6 47.8 111.7 128.0 64.2 61.8 70.5 53.6 60.2 84.0 66.7 0.1 0.0 2.3 209.6 0.0 1.3 1.2 1.5 4.0 17.0 3.2 3.4 7.6 2.8 4.7 3.7 8.4 0.2 0.1 0.2 13.7 6.0 36.7 8.5 2.7 1.8 22.9 0.0 204.7 0.2 3.6 2.7 3.1 4.4 2.5 5.7 0.4 0.0 0.2 1.7 301.5 2.6 8.2 0.0 1.6 39.8 0.6 0.4 7.2 98.4 0.1 5.9 2.1 232.7 136.9 2.4 2.3 3.0 0.0 2.2 0.3 1.0 1.6 9.3 6.6 2.6 2.5 2.1 3.0 0.5 0.3 2.7 0.6 1.9 1.3 1.4 ARSL "ARSE, CDPX, CDPX1" ENSG00000157399 "Arylsulfatase L" P51690 X 2934521-2968475 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 36.6;liver: 86.3;pancreas: 105.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 34.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 68.9;CACO-2: 42.7;GAMG: 30.8;Hep G2: 64.1;NTERA-2: 33.6" "Low region specificity" "Detected in all" "HPA060518, HPA070651" Approved Supported "Golgi apparatus" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA060518: AB_2684301, HPA070651: AB_2732160" "unprognostic (2.07e-1)" "unprognostic (6.60e-3)" "prognostic favorable (8.95e-4)" "unprognostic (8.74e-3)" "unprognostic (1.14e-3)" "unprognostic (3.48e-2)" "unprognostic (2.38e-1)" "unprognostic (8.27e-2)" "unprognostic (5.45e-2)" "unprognostic (2.25e-1)" "unprognostic (2.27e-1)" "unprognostic (2.37e-1)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (1.28e-1)" "unprognostic (5.94e-2)" "unprognostic (4.76e-2)" 0.4 0.7 2.6 2.2 2.7 0.3 1.1 2.1 2.8 1.7 4.5 20.8 17.9 3.2 2.2 0.4 4.1 8.2 1.0 2.8 2.6 36.6 86.3 2.7 0.1 2.8 2.8 7.1 105.2 0.0 0.7 0.7 2.9 0.5 16.7 0.3 1.3 2.9 0.2 0.2 13.6 1.9 2.4 0.0 2.9 0.4 2.6 0.0 0.2 0.3 0.1 0.5 1.6 2.3 4.5 68.9 8.2 0.0 3.3 4.0 1.3 3.9 6.4 4.0 4.0 42.7 0.0 0.0 13.7 0.1 30.8 0.0 0.0 0.9 2.3 0.0 4.5 0.0 0.0 64.1 1.8 0.0 0.1 9.6 0.0 3.8 0.0 7.3 3.8 0.0 0.0 0.1 10.5 0.1 0.0 0.0 33.6 2.4 0.2 2.8 1.1 0.3 7.1 0.0 0.1 0.2 0.0 0.0 2.6 13.7 0.0 0.2 5.0 0.1 0.2 0.0 7.4 0.0 0.0 0.1 9.1 0.1 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.7 2.1 2.8 2.8 2.6 2.8 2.8 2.9 2.4 2.6 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ARX "CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS" ENSG00000004848 "Aristaless related homeobox" Q96QS3 X 25003694-25016420 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Epilepsy, Lissencephaly, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.4;ovary: 78.7;skeletal muscle: 26.7" "Group enriched" "Detected in some" 5 "Enteroendocrine cells: 83.7;Inhibitory neurons: 53.2;Leydig cells: 131.7;Peritubular cells: 70.0;Theca cells: 66.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.9;PC-3: 3.9;THP-1: 1.7;U-266/70: 8.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "unprognostic (8.28e-2)" "unprognostic (3.06e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (3.54e-7)" "unprognostic (9.85e-2)" "unprognostic (7.96e-3)" "unprognostic (1.18e-1)" "unprognostic (2.77e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-3)" "unprognostic (1.32e-1)" "unprognostic (1.06e-6)" "unprognostic (6.01e-2)" "unprognostic (1.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.91e-1)" 0.0 0.1 7.6 0.0 10.1 0.0 0.3 0.0 17.4 0.0 0.0 0.9 3.5 0.0 0.1 0.1 1.1 0.0 0.0 10.1 6.0 0.1 0.0 0.4 0.0 0.0 0.0 78.7 1.4 1.8 0.3 0.0 0.1 0.7 0.9 0.0 0.2 0.0 26.7 0.0 0.7 0.0 0.0 0.2 5.5 7.2 0.4 0.0 0.2 1.9 0.4 0.0 0.2 8.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 1.9 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 3.9 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.1 0.0 0.0 8.3 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 10.1 0.0 17.4 10.1 6.0 0.0 0.0 0.1 0.0 0.4 8.0 0.0 0.0 0.0 14.0 0.3 0.0 2.5 0.5 0.0 0.0 0.3 0.0 0.5 0.0 2.2 0.0 0.0 0.2 0.1 1.9 0.0 0.0 1.2 0.0 0.0 0.1 83.7 0.0 0.2 0.0 2.4 4.7 4.6 0.0 0.0 0.4 0.0 0.0 0.1 0.0 53.2 3.6 4.1 0.0 0.0 3.6 131.7 0.2 0.0 3.7 0.0 0.0 0.0 3.5 0.6 0.3 0.8 70.0 0.9 1.3 0.1 0.1 11.3 0.0 0.0 1.5 0.3 0.5 0.3 0.0 0.0 0.1 0.3 66.8 1.9 1.6 ASPH "BAH, CASQ2BP1, HAAH, JCTN" ENSG00000198363 "Aspartate beta-hydroxylase" Q12797 8 61500556-61714640 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Dioxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 386.9" "Cell type enhanced" "Detected in all" "Muller glia cells: 468.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 34.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 890.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055161, HPA059303" Uncertain Enhanced "Endoplasmic reticulum" NA NA 1100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "HPA055161: AB_2682721, HPA059303: AB_2683973" "unprognostic (8.07e-2)" "prognostic unfavorable (8.07e-5)" "unprognostic (1.73e-2)" "unprognostic (4.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.85e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (6.39e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.57e-5)" "unprognostic (8.96e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (2.74e-2)" 386.9 160.3 64.7 50.6 69.2 16.9 106.9 102.3 88.9 65.6 84.4 78.8 45.6 49.3 44.7 71.4 46.9 61.0 111.3 64.5 58.4 59.5 74.9 74.1 20.3 54.0 69.2 62.2 44.7 38.7 36.3 47.9 52.2 48.3 84.9 219.5 101.9 70.2 357.6 35.2 45.5 67.5 44.8 28.6 105.0 16.5 71.8 16.7 97.0 182.7 28.5 112.2 43.8 60.4 460.3 652.3 89.9 55.1 392.1 370.1 31.2 804.0 741.3 336.3 350.1 113.1 594.2 35.3 54.3 474.6 270.3 167.5 56.2 281.1 570.0 13.6 57.0 81.1 372.5 310.3 251.2 12.5 12.9 306.5 61.9 187.6 237.4 657.2 144.8 18.0 22.2 32.1 300.2 97.4 3.3 16.6 51.7 441.6 383.4 22.3 97.0 7.3 206.2 374.0 93.1 32.1 249.9 116.1 101.7 49.0 47.7 22.2 456.7 338.0 174.3 313.0 288.0 20.2 27.1 1.5 890.1 7.5 231.4 1.9 8.3 0.3 2.5 2.9 4.7 5.5 3.5 2.4 10.0 5.0 4.9 2.5 25.4 8.7 1.8 34.0 4.0 4.1 64.7 69.2 102.3 88.9 64.5 58.4 54.0 69.2 52.2 44.8 71.8 60.4 79.1 195.5 244.0 366.6 13.8 47.0 160.7 126.0 68.9 138.3 83.7 58.4 228.6 37.1 157.5 86.5 294.0 118.1 40.3 57.0 15.6 144.2 1.6 51.4 65.8 85.9 116.5 13.0 93.1 180.4 107.1 132.0 73.9 115.4 8.2 34.5 42.8 62.6 72.2 127.9 98.9 215.1 52.9 26.6 44.1 3.1 70.8 48.1 42.7 61.8 20.0 468.8 2.1 154.8 53.5 257.7 32.3 57.6 15.9 148.2 34.3 34.6 66.6 158.8 46.0 114.4 92.7 3.4 16.8 101.7 50.3 48.0 13.6 131.2 67.3 254.2 ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Assembly factor for spindle microtubules" Q8IZT6 1 197084121-197146694 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 10.1;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 99.5;Granulosa cells: 121.1;Plasma cells: 44.8;Spermatocytes: 43.8;Spermatogonia: 44.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017816 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.67e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.67e-3)" "unprognostic (9.29e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.03e-1)" "unprognostic (0.00e+0)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (3.66e-2)" 0.2 0.1 0.0 3.0 0.0 10.1 0.4 0.0 0.1 0.2 0.0 1.6 2.1 0.3 0.0 1.5 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 5.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 1.9 0.0 0.2 0.0 0.0 2.7 1.9 0.7 0.0 0.9 1.1 3.2 0.1 17.0 0.1 0.0 5.1 0.6 0.4 0.2 44.6 22.9 39.1 23.2 1.9 5.5 14.7 35.1 23.2 32.6 25.6 16.7 31.1 45.4 12.5 27.5 13.8 40.2 33.6 12.1 39.1 41.8 25.4 33.1 56.1 12.8 0.4 51.9 20.5 0.6 1.0 26.1 15.2 7.3 31.5 32.9 41.8 50.7 29.0 16.0 40.6 10.3 17.8 24.8 6.4 30.2 55.5 31.7 7.4 11.4 20.4 29.5 50.6 20.6 9.5 20.8 26.9 12.7 28.9 20.9 20.0 34.9 61.2 13.9 21.6 26.8 14.9 11.0 42.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.0 1.1 1.3 5.8 6.1 1.5 4.0 2.2 0.1 2.4 2.4 1.1 0.0 1.3 1.8 0.0 20.0 7.8 7.7 0.0 0.3 3.9 2.9 6.2 4.3 0.0 99.5 2.0 0.0 14.8 9.8 13.3 8.1 1.3 121.1 6.4 2.2 11.6 0.0 4.8 6.8 4.1 6.4 2.4 4.5 0.6 6.4 0.0 0.0 0.9 0.7 4.1 0.0 1.0 0.5 0.2 1.5 44.8 2.0 0.4 0.4 0.8 0.3 0.0 0.6 7.0 43.8 44.7 27.1 3.4 3.7 9.1 5.7 16.9 2.1 ASPRV1 "FLJ25084, SASPase, Taps" ENSG00000244617 "Aspartic peptidase retroviral like 1" Q53RT3 2 69960089-69962265 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "skin 1: 424.0" "Cell type enhanced" "Detected in some" "NK-cells: 3.1;Oligodendrocytes: 4.2;Spermatogonia: 3.3;Suprabasal keratinocytes: 10.7" "Group enriched" "Detected in many" 8 "head and neck cancer: 23.1;melanoma: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 8.7" "Lineage enriched" "Detected in single" 10 "granulocytes: 8.7" "Cell line enhanced" "Detected in some" "NB-4: 2.9;REH: 4.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA034809, HPA034810" Enhanced Approved Cytosol NA NA 150000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 14: REH - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA034809: AB_2674343, HPA034810: AB_10601456" "unprognostic (4.75e-4)" "unprognostic (1.90e-3)" "unprognostic (2.34e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (1.17e-2)" "unprognostic (1.93e-3)" "unprognostic (1.51e-1)" "unprognostic (1.36e-1)" "unprognostic (2.51e-1)" "unprognostic (4.19e-3)" "unprognostic (1.27e-1)" "unprognostic (4.01e-2)" "unprognostic (3.00e-1)" "unprognostic (1.74e-1)" "unprognostic (4.84e-2)" "unprognostic (2.43e-2)" 2.6 2.1 5.8 0.9 7.3 0.9 17.1 6.1 6.6 3.1 3.0 1.7 1.6 2.5 2.6 0.9 2.3 1.1 1.8 5.3 6.0 2.2 1.9 1.7 1.0 7.2 6.7 4.8 0.7 0.2 4.0 0.9 6.5 2.2 0.6 1.5 1.3 1.3 4.4 424.0 1.7 1.2 6.0 3.9 1.2 3.6 6.5 2.1 1.3 2.1 1.0 1.5 4.5 9.3 0.0 0.3 0.9 1.9 1.2 0.4 0.2 0.2 0.4 0.2 0.1 0.6 0.0 0.7 0.1 0.2 0.2 0.2 0.8 0.1 0.2 1.3 2.5 1.5 0.2 0.6 0.4 1.3 1.0 0.5 0.4 0.2 0.4 0.3 0.2 1.6 0.5 1.9 0.2 0.3 1.1 2.9 1.0 0.2 0.2 4.9 0.5 0.3 0.0 0.0 1.0 0.2 0.1 0.7 0.8 0.2 0.0 0.5 0.1 0.0 0.9 0.0 0.2 2.0 1.3 1.4 0.1 0.9 1.0 0.0 0.1 1.5 0.5 0.1 0.5 0.0 0.2 0.4 0.0 0.1 0.1 0.4 8.7 0.3 0.0 0.8 0.7 0.4 5.8 7.3 6.1 6.6 5.3 6.0 7.2 6.7 6.5 6.0 6.5 9.3 1.1 0.0 0.0 1.3 0.0 0.4 0.1 0.2 0.0 1.1 0.5 0.9 2.6 0.0 0.1 1.8 0.0 0.3 0.1 0.5 0.0 0.1 0.1 0.4 0.5 0.8 0.0 0.0 1.0 0.2 0.0 0.7 0.0 0.4 0.0 1.1 1.4 0.1 0.2 0.0 1.5 0.9 0.0 0.3 0.6 0.5 0.9 0.3 0.0 1.0 0.2 1.2 3.1 1.5 4.2 0.3 0.0 0.7 0.1 0.2 1.1 0.9 0.2 1.6 0.0 0.7 1.1 1.4 3.3 0.0 10.7 0.4 0.2 0.5 0.2 0.1 ASXL1 KIAA0978 ENSG00000171456 "ASXL transcriptional regulator 1" Q8IXJ9 20 32358330-32439319 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor" "Cancer-related genes, Craniosynostosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064156 Approved Nucleoplasm,Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "HPA064156: AB_2685200" "unprognostic (1.49e-1)" "unprognostic (5.97e-2)" "unprognostic (8.36e-2)" "prognostic unfavorable (2.86e-4)" "unprognostic (6.69e-2)" "prognostic favorable (9.16e-4)" "unprognostic (2.01e-3)" "unprognostic (2.89e-1)" "unprognostic (1.49e-1)" "unprognostic (1.38e-1)" "unprognostic (4.32e-2)" "unprognostic (3.21e-2)" "unprognostic (1.84e-3)" "unprognostic (5.47e-2)" "unprognostic (1.90e-1)" "unprognostic (4.82e-2)" "unprognostic (1.06e-1)" 31.6 24.6 13.4 18.1 14.4 36.9 30.5 15.0 14.4 30.6 20.2 31.6 12.2 26.8 15.6 17.2 28.6 13.7 21.8 14.1 15.6 28.7 32.8 36.0 24.0 15.8 14.2 32.3 32.9 13.1 19.2 17.3 13.8 24.8 13.2 19.7 21.0 13.3 30.1 23.2 27.8 18.4 13.8 35.0 24.7 37.2 15.1 27.4 32.0 16.4 25.0 26.4 24.2 17.1 59.2 33.6 52.7 28.2 23.6 28.6 45.6 35.4 33.0 64.1 48.6 99.8 35.2 54.4 24.5 47.3 62.2 39.5 45.3 37.8 53.2 70.6 24.1 88.9 53.6 55.7 21.6 38.5 36.1 32.4 25.1 46.1 35.6 33.3 37.4 45.3 45.2 29.1 31.9 18.4 51.7 30.3 12.9 27.7 38.9 30.8 62.1 24.8 27.1 28.4 23.7 38.2 68.9 23.5 31.7 27.9 32.7 27.0 39.9 69.1 59.4 32.3 43.2 33.9 38.6 39.3 34.0 100.2 27.8 0.1 0.6 1.0 2.6 0.5 2.5 4.8 3.6 3.9 0.8 3.3 3.5 4.0 0.5 1.5 0.6 2.7 9.0 1.5 13.4 14.4 15.0 14.4 14.1 15.6 15.8 14.2 13.8 13.8 15.1 17.1 92.3 51.3 35.5 54.9 63.3 40.0 51.8 8.6 50.7 21.4 52.9 48.6 19.8 15.7 17.9 27.6 52.1 18.0 55.2 18.8 25.4 13.5 97.8 59.4 80.1 65.6 7.2 40.8 61.4 12.6 16.5 49.8 30.5 86.2 18.3 57.7 41.0 34.7 21.3 18.5 80.3 14.1 16.2 21.2 42.2 84.9 25.4 33.5 78.2 75.9 16.7 11.6 20.6 78.4 125.9 15.6 13.7 14.7 94.6 49.6 29.9 31.7 20.8 30.7 6.6 96.7 62.7 31.0 16.1 34.6 30.5 5.9 67.2 36.4 17.5 40.5 ASXL3 KIAA1713 ENSG00000141431 "ASXL transcriptional regulator 3" Q9C0F0 18 33578219-33751195 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 2.2" "Group enriched" "Detected in many" 6 "Early spermatids: 52.5;Excitatory neurons: 125.1;Inhibitory neurons: 101.1;Late spermatids: 31.6;Oligodendrocyte precursor cells: 88.4;Oligodendrocytes: 62.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.4;RPMI-8226: 7.4;SCLC-21H: 2.8;SH-SY5Y: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039539, HPA040034" Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA039539: , HPA040034: " "unprognostic (2.05e-2)" "unprognostic (6.88e-2)" "unprognostic (2.91e-1)" "unprognostic (3.73e-4)" "unprognostic (1.30e-1)" "unprognostic (3.19e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "unprognostic (9.16e-2)" "unprognostic (5.35e-3)" "unprognostic (5.92e-2)" "unprognostic (2.47e-12)" "unprognostic (4.69e-2)" "unprognostic (2.32e-1)" "unprognostic (4.98e-3)" "unprognostic (1.67e-2)" 0.2 0.0 1.7 0.0 1.4 0.0 0.2 0.0 1.9 0.7 0.1 0.6 0.2 0.3 0.3 0.0 0.5 0.4 0.5 1.5 0.7 0.6 0.4 0.2 0.0 0.4 0.2 2.2 0.3 0.2 0.7 0.0 0.1 0.6 0.1 0.5 0.2 0.6 0.0 0.1 0.3 0.2 0.1 0.1 0.8 1.6 0.1 0.0 0.9 0.0 0.0 0.5 0.4 0.7 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.4 0.0 0.0 2.8 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.4 0.0 1.9 1.5 0.7 0.4 0.2 0.1 0.1 0.1 0.7 1.0 0.0 0.0 11.1 0.0 0.1 1.0 0.0 1.2 5.3 0.2 0.9 4.8 1.5 3.1 1.8 0.0 0.6 0.0 1.0 1.9 1.7 52.5 0.1 1.5 0.4 3.0 0.0 125.1 0.0 0.2 3.2 3.1 0.1 1.3 0.0 0.4 2.0 0.2 1.7 101.1 0.7 0.0 0.0 0.0 31.6 2.1 0.1 0.0 10.3 0.0 1.0 0.0 88.4 62.2 0.4 0.4 1.9 0.0 0.4 1.5 1.2 0.0 0.9 0.0 1.1 2.6 2.9 3.7 0.2 0.0 0.4 0.0 11.2 0.6 0.3 ATP1A3 DYT12 ENSG00000105409 "ATPase Na+/K+ transporting subunit alpha 3" P13637 19 41966582-41997497 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Deafness, Disease variant, Dystonia, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 645.2;heart muscle: 157.7;retina: 292.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 418.1;Cone photoreceptor cells: 171.0;Horizontal cells: 213.7;Inhibitory neurons: 119.1;Late spermatids: 115.6;Rod photoreceptor cells: 291.4" "Cancer enriched" "Detected in many" 5 "glioma: 21.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 57.7;JURKAT: 36.3;Karpas-707: 35.9;REH: 37.1;SCLC-21H: 128.2;SH-SY5Y: 57.7" "CAB033630, HPA045367, HPA056446" Enhanced Approved NA NA 220000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "CAB033630: AB_781528, HPA045367: AB_2679297, HPA056446: AB_2683136" "unprognostic (1.90e-1)" "unprognostic (8.65e-2)" "unprognostic (4.57e-2)" "unprognostic (8.20e-3)" "unprognostic (8.94e-2)" "unprognostic (2.52e-1)" "unprognostic (3.16e-2)" "unprognostic (7.66e-2)" "unprognostic (8.02e-2)" "prognostic unfavorable (3.44e-4)" "prognostic favorable (6.15e-5)" "unprognostic (4.02e-3)" "prognostic unfavorable (3.02e-6)" "unprognostic (6.84e-2)" "unprognostic (6.48e-2)" "unprognostic (3.45e-1)" "unprognostic (1.27e-1)" 0.2 18.0 115.4 1.4 126.3 0.6 0.1 76.0 645.2 0.0 0.0 3.6 0.9 0.0 0.0 0.3 0.0 0.2 157.7 165.8 275.3 0.1 0.1 0.2 0.9 390.1 61.8 0.1 0.8 1.2 15.4 0.0 320.4 0.2 0.8 292.4 0.8 0.0 0.2 0.3 1.5 0.8 26.3 0.5 1.3 31.5 174.9 2.1 0.2 1.8 0.6 0.1 0.7 200.7 0.0 2.1 0.7 23.1 0.0 0.1 0.1 0.3 0.0 1.6 1.6 0.8 4.3 57.7 2.6 0.4 5.6 0.5 16.2 0.2 0.6 10.7 3.1 5.0 0.2 0.4 0.0 0.0 18.2 0.0 0.2 0.0 0.3 0.3 0.0 36.3 0.0 35.9 0.4 0.8 10.4 0.1 3.0 8.4 14.3 37.1 18.5 1.8 0.0 0.6 128.2 57.7 0.3 4.2 0.1 0.0 3.4 2.6 0.0 3.0 3.2 0.0 1.1 3.7 2.6 12.7 5.5 20.6 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 115.4 126.3 76.0 645.2 165.8 275.3 390.1 61.8 320.4 26.3 174.9 200.7 0.2 0.0 4.4 9.1 1.1 0.3 0.4 0.0 0.6 418.1 0.3 0.3 19.3 0.0 0.0 0.0 171.0 0.0 3.2 0.8 0.0 0.0 43.7 0.1 0.1 1.4 0.0 0.0 59.1 0.0 0.1 1.0 1.1 0.1 1.3 0.1 0.0 0.0 0.2 213.7 119.1 0.4 0.0 0.0 0.4 115.6 1.8 0.7 0.0 8.4 0.4 40.0 6.2 14.6 11.4 0.0 0.0 0.4 1.0 0.2 0.0 0.1 0.0 291.4 0.0 0.7 0.4 21.2 2.8 0.2 0.3 0.3 3.6 0.4 0.5 0.4 ATP2A2 "ATP2B, DAR, SERCA2" ENSG00000174437 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2" P16615 12 110280756-110351093 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "heart muscle: 1005.8;skeletal muscle: 2856.8;tongue: 2768.8" "Cell type enriched" "Detected in all" 7 "Cardiomyocytes: 2119.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062605 Enhanced NA NA 2500000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA062605: AB_2684805" "unprognostic (4.81e-2)" "unprognostic (2.16e-2)" "unprognostic (1.87e-1)" "unprognostic (3.41e-3)" "unprognostic (2.50e-1)" "unprognostic (3.98e-3)" "unprognostic (1.91e-2)" "unprognostic (6.20e-2)" "unprognostic (4.69e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (1.36e-3)" "unprognostic (2.26e-1)" "unprognostic (5.62e-2)" "unprognostic (9.93e-2)" 60.4 49.6 26.2 57.8 34.6 46.0 34.1 36.0 28.0 43.4 23.2 64.2 47.5 46.6 39.0 181.2 67.0 60.5 1005.8 39.0 28.8 34.4 54.7 49.0 36.0 32.5 46.3 42.0 38.1 56.1 24.5 55.4 29.8 93.4 69.0 19.1 92.2 70.0 2856.8 46.5 56.4 74.4 29.8 30.5 47.2 74.1 57.6 36.2 73.3 2768.8 48.1 90.9 57.9 36.1 129.7 305.7 135.4 106.5 95.3 111.7 185.1 154.9 197.2 163.6 102.1 229.1 131.3 155.4 129.2 165.4 115.4 185.0 215.9 264.4 157.3 130.0 127.2 148.0 115.6 121.5 164.7 151.1 130.6 130.3 170.7 202.3 190.1 165.4 134.9 82.6 162.9 74.9 118.6 131.3 76.0 53.2 139.7 126.6 134.8 96.8 130.2 128.6 59.5 279.2 138.2 101.5 207.8 151.1 87.0 113.9 213.7 95.6 159.8 147.8 69.3 93.9 127.4 140.6 189.5 169.0 152.3 70.9 168.8 0.0 0.6 0.0 0.5 1.3 0.2 0.1 0.3 0.2 0.5 0.2 0.3 0.3 0.0 0.3 0.6 0.5 0.3 0.2 26.2 34.6 36.0 28.0 39.0 28.8 32.5 46.3 29.8 29.8 57.6 36.1 48.9 44.8 57.5 85.5 26.3 114.5 95.2 134.5 68.9 63.6 70.2 64.6 2119.9 41.5 103.5 51.5 64.6 33.4 37.4 155.1 1.9 43.7 14.8 291.6 90.8 59.7 137.3 14.1 161.0 71.0 37.6 104.2 49.5 258.1 45.0 47.3 40.7 122.2 64.3 84.1 146.1 109.6 65.1 54.6 64.9 13.4 30.4 65.3 67.6 63.7 33.8 27.5 15.5 119.6 96.4 98.0 89.4 83.1 56.8 117.4 78.0 25.3 176.4 42.9 52.6 88.0 110.2 80.3 47.7 142.3 109.0 30.6 32.7 40.0 97.7 126.4 ATP2C1 "ATP2C1A, BCPM, KIAA1347, PMR1, SPCA1" ENSG00000017260 "ATPase secretory pathway Ca2+ transporting 1" P98194 3 130850595-131016712 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 162.6;Excitatory neurons: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010207, HPA035116, HPA069684" Supported Supported "Golgi apparatus" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "CAB010207: AB_2061744, HPA035116: AB_10673106, HPA069684: AB_2686169" "unprognostic (1.52e-1)" "unprognostic (1.37e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.32e-2)" "prognostic unfavorable (5.06e-6)" "unprognostic (7.66e-2)" "unprognostic (6.52e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.52e-4)" "unprognostic (8.44e-2)" "prognostic favorable (1.55e-4)" "unprognostic (2.19e-1)" "unprognostic (1.95e-1)" "unprognostic (3.73e-2)" "unprognostic (3.06e-1)" 32.2 32.7 34.0 25.3 36.6 38.6 32.9 31.8 42.8 33.4 76.9 36.5 23.9 30.9 28.0 23.6 37.2 27.2 31.9 40.7 38.6 44.7 28.5 51.4 21.9 37.0 38.9 28.8 22.6 78.0 22.7 32.7 40.3 85.8 35.9 59.4 29.2 25.2 28.1 31.9 26.9 31.0 33.6 19.5 31.5 25.2 48.8 36.2 35.0 21.1 26.2 31.6 18.1 48.6 133.1 51.1 49.9 48.5 136.7 110.0 53.9 141.2 186.8 69.4 87.0 83.5 106.3 47.6 95.6 134.4 96.4 153.6 95.1 77.9 100.8 104.4 34.2 127.2 51.5 39.0 87.2 51.2 148.4 86.8 76.6 73.2 82.2 126.3 74.6 59.3 37.3 84.1 86.7 59.0 50.6 40.9 57.0 71.7 54.8 36.3 49.9 75.6 127.5 87.7 76.7 45.9 121.4 37.8 72.8 70.8 55.7 41.7 102.6 73.3 40.8 95.5 65.8 54.6 71.1 69.9 75.8 38.0 62.6 30.6 8.9 15.9 7.4 7.6 7.0 5.6 7.3 6.6 9.5 3.6 4.9 4.9 4.3 11.5 9.6 8.2 9.3 6.5 34.0 36.6 31.8 42.8 40.7 38.6 37.0 38.9 40.3 33.6 48.8 48.6 30.2 38.5 53.0 162.6 17.4 39.4 34.5 34.8 26.7 25.9 34.4 22.4 30.2 35.8 41.1 46.0 20.9 16.3 15.5 39.0 5.9 35.3 17.5 26.9 34.1 27.8 35.6 23.3 172.5 38.0 27.6 25.9 33.1 55.8 28.5 28.2 26.7 27.4 27.7 82.4 136.5 32.4 36.7 26.2 34.8 18.9 16.1 39.5 21.4 128.4 20.5 26.4 19.6 148.3 154.3 51.1 27.5 14.7 18.5 69.0 16.3 19.8 52.7 33.4 6.6 27.7 25.9 16.2 14.1 24.7 52.8 17.6 19.5 17.3 31.2 36.9 ATP6V0A2 "a2, ATP6a2, ATP6N1D, J6B7, Stv1, TJ6, TJ6M, TJ6s, Vph1" ENSG00000185344 "ATPase H+ transporting V0 subunit a2" Q9Y487 12 123712353-123761755 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 51.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044279 Approved Supported "Vesicles,Plasma membrane,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Vesicles, Focal adhesion sites" "HPA044279: AB_10961274" "unprognostic (2.60e-1)" "unprognostic (8.79e-3)" "unprognostic (3.60e-2)" "unprognostic (1.50e-1)" "unprognostic (2.70e-1)" "unprognostic (2.29e-2)" "unprognostic (2.06e-4)" "unprognostic (1.40e-1)" "unprognostic (3.77e-2)" "unprognostic (1.75e-1)" "unprognostic (8.85e-3)" "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" "unprognostic (7.48e-2)" "unprognostic (1.12e-1)" "unprognostic (3.47e-1)" "unprognostic (1.58e-1)" 6.6 4.4 5.6 7.0 6.2 10.4 5.7 7.4 6.5 4.7 6.9 5.5 8.7 6.0 3.9 4.3 4.8 3.8 4.7 6.0 6.0 3.8 4.2 6.3 8.3 6.6 5.8 4.1 5.7 3.7 4.9 3.7 6.5 4.7 5.8 6.7 7.6 4.0 6.5 9.4 7.0 5.1 5.6 6.6 8.8 4.9 6.2 7.5 4.8 3.5 8.2 5.3 4.5 7.9 4.8 10.3 12.0 17.8 9.2 7.0 6.7 6.2 6.2 5.4 5.8 6.9 2.7 18.0 4.2 7.6 5.5 9.0 16.1 6.2 4.5 11.4 10.2 27.9 9.2 5.4 10.2 16.8 51.0 6.7 4.4 5.9 7.4 9.0 5.0 15.0 14.5 3.4 8.1 8.4 15.4 24.8 11.5 6.6 6.5 15.7 9.9 6.4 8.3 10.4 7.2 13.6 9.3 6.9 9.4 6.6 5.9 14.4 8.3 8.0 3.1 10.8 9.1 10.8 12.8 14.9 9.4 12.1 6.5 6.3 0.7 13.7 1.7 0.9 1.0 0.9 1.7 1.5 0.8 3.7 1.6 1.8 2.0 1.7 1.5 2.8 1.0 0.8 5.6 6.2 7.4 6.5 6.0 6.0 6.6 5.8 6.5 5.6 6.2 7.9 13.0 6.4 11.0 3.9 20.4 10.1 10.8 4.6 11.4 20.5 7.9 5.3 8.8 12.8 8.3 9.2 12.5 5.2 27.9 17.9 0.0 8.1 10.2 11.0 11.9 10.6 13.2 50.3 21.2 10.9 5.7 11.3 18.3 12.3 75.3 8.7 18.2 11.4 8.4 11.8 19.3 9.8 2.0 9.4 17.2 4.5 8.7 11.3 1.8 7.5 13.2 9.0 25.7 10.6 17.1 9.2 9.0 9.4 19.7 15.7 11.1 4.0 13.5 28.8 6.6 12.4 10.9 23.6 12.6 9.6 14.2 6.8 21.8 5.7 11.4 11.4 ATP6V1B2 "ATP6B2, HO57, VATB, Vma2, VPP3" ENSG00000147416 "ATPase H+ transporting V1 subunit B2" P21281 8 20197381-20226819 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 256.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1130.7" "Group enriched" "Detected in all" 10 "dendritic cells: 336.8;granulocytes: 1130.7;monocytes: 682.0" "Cell line enhanced" "Detected in all" "SK-MEL-30: 317.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008147 Enhanced Supported Vesicles NA NA 310000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA008147: AB_1845195" "unprognostic (1.90e-1)" "unprognostic (7.24e-3)" "unprognostic (3.62e-2)" "unprognostic (2.57e-1)" "unprognostic (2.84e-2)" "unprognostic (5.59e-3)" "unprognostic (1.76e-2)" "unprognostic (3.78e-2)" "unprognostic (4.68e-2)" "unprognostic (4.23e-3)" "unprognostic (1.29e-2)" "unprognostic (1.34e-1)" "prognostic favorable (8.41e-4)" "unprognostic (2.41e-1)" "unprognostic (2.09e-2)" "unprognostic (2.47e-2)" "unprognostic (5.25e-2)" 46.4 76.4 112.6 71.9 111.2 45.7 35.3 72.8 126.0 30.1 72.5 38.0 43.9 29.4 31.0 51.3 32.8 39.0 38.2 124.0 135.5 145.8 49.2 72.7 54.1 103.4 120.0 27.5 34.5 71.4 74.5 50.5 138.2 28.1 43.0 205.7 40.4 27.0 66.7 62.5 57.8 40.1 74.8 66.1 32.8 67.8 100.3 50.2 33.4 64.7 48.9 44.5 36.1 99.5 44.2 71.5 87.4 29.2 117.7 72.3 79.1 96.6 61.5 121.5 125.2 81.7 25.4 77.7 38.4 93.1 123.7 36.8 70.1 64.6 129.0 32.9 47.2 54.2 29.9 63.6 137.6 39.0 108.0 65.0 57.9 76.0 69.3 134.1 77.2 101.2 82.0 72.8 132.5 25.0 114.6 46.2 65.6 64.6 31.5 46.6 113.4 40.8 112.9 68.2 68.0 97.9 46.9 62.7 317.9 72.4 81.6 70.7 82.8 61.1 46.3 101.9 78.5 29.4 42.7 90.9 84.6 91.6 158.4 183.7 682.0 485.9 52.9 618.6 57.7 50.2 54.1 56.8 336.8 44.5 54.4 53.7 1130.7 50.8 576.1 82.7 73.0 622.6 112.6 111.2 72.8 126.0 124.0 135.5 103.4 120.0 138.2 74.8 100.3 99.5 16.6 25.6 20.7 20.5 28.1 58.0 28.4 52.1 33.0 106.1 18.5 15.6 17.6 25.8 28.8 29.5 102.2 109.2 38.9 23.3 80.3 43.2 40.8 20.2 13.6 24.1 74.4 35.8 64.3 38.5 56.4 38.8 25.0 35.9 22.2 22.3 25.7 34.7 178.5 190.1 68.0 21.4 36.7 185.2 178.7 24.4 19.6 167.6 104.9 30.0 169.1 51.5 20.6 27.6 29.0 45.2 19.7 28.2 20.7 17.4 75.0 256.7 18.0 137.8 13.1 29.3 34.2 121.6 55.3 43.3 71.6 124.6 27.1 23.1 24.7 20.1 ATP6V1E1 "ATP6E, ATP6E2, ATP6V1E, P31, Vma4" ENSG00000131100 "ATPase H+ transporting V1 subunit E1" P36543 22 17592136-17628749 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 461.8;Proximal tubular cells: 411.3;Syncytiotrophoblasts: 479.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009528, CAB018699, HPA029196" Enhanced Approved Nucleoplasm NA NA 34000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB009528: AB_2062678, CAB018699: AB_781534, HPA029196: AB_2672944" "unprognostic (1.53e-3)" "unprognostic (5.78e-3)" "unprognostic (1.31e-2)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.24e-3)" "prognostic unfavorable (1.56e-5)" "unprognostic (2.17e-1)" "unprognostic (2.09e-1)" "unprognostic (3.37e-2)" "unprognostic (7.72e-3)" "prognostic favorable (4.18e-4)" "prognostic favorable (7.66e-8)" "unprognostic (3.81e-2)" "unprognostic (1.28e-1)" "unprognostic (2.58e-2)" "unprognostic (2.75e-1)" 119.5 165.0 209.8 68.3 220.9 90.4 109.5 214.3 287.3 101.7 200.4 128.9 56.6 112.2 135.8 117.2 96.0 84.7 224.9 231.8 226.9 230.5 85.6 110.3 88.6 220.3 202.3 81.9 59.5 239.9 117.1 113.8 230.8 95.0 99.7 128.4 83.7 126.4 232.8 120.3 83.1 121.0 215.9 99.0 101.8 67.3 218.1 108.2 100.8 178.6 109.5 114.5 97.6 245.6 121.8 108.6 96.4 94.3 314.4 169.6 106.0 159.3 212.0 198.7 228.0 137.3 97.5 76.1 132.8 215.0 251.8 187.9 152.8 140.2 174.9 145.9 173.3 137.1 97.5 182.7 459.9 159.8 226.5 212.9 267.7 192.4 138.7 220.9 170.2 95.0 174.8 150.3 341.9 127.4 136.5 114.5 71.0 269.6 152.6 80.3 140.7 45.7 331.6 189.0 70.3 122.7 146.0 101.0 358.9 187.0 98.6 180.4 146.3 137.5 72.6 174.0 119.2 145.7 275.5 96.3 221.2 76.7 189.3 178.1 106.3 184.7 64.0 100.9 63.0 78.7 64.7 61.5 83.6 59.8 60.8 63.7 137.6 76.0 120.5 81.2 97.7 112.8 209.8 220.9 214.3 287.3 231.8 226.9 220.3 202.3 230.8 215.9 218.1 245.6 66.5 76.9 83.4 13.4 47.1 41.9 77.6 121.8 19.9 54.6 33.9 34.8 126.8 74.4 83.9 138.0 27.1 235.1 63.8 105.2 461.8 143.8 7.6 74.3 56.9 69.3 41.9 49.4 24.9 119.7 143.9 60.8 40.8 79.2 90.5 41.6 72.5 46.8 186.8 53.8 24.4 54.0 116.0 75.1 52.1 17.9 94.1 91.9 80.0 15.0 144.1 94.1 85.5 13.0 31.9 154.7 104.7 97.8 38.3 60.1 65.4 411.3 78.8 50.4 59.2 39.0 74.5 71.7 74.7 34.3 51.6 479.1 54.6 57.6 40.1 93.1 ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449007-142578733 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.0;Inhibitory neurons: 94.4;Microglial cells: 73.1;Oligodendrocyte precursor cells: 65.4;Oligodendrocytes: 71.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054320 Supported "Nucleoplasm,Golgi apparatus" No No "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Golgi apparatus" "HPA054320: AB_2682448" "unprognostic (1.47e-1)" "unprognostic (8.90e-2)" "unprognostic (2.90e-1)" "unprognostic (4.23e-2)" "unprognostic (2.25e-2)" "unprognostic (6.42e-2)" "prognostic unfavorable (8.39e-5)" "unprognostic (3.44e-1)" "unprognostic (1.67e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.94e-1)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-1)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" 3.0 8.6 0.7 4.1 1.1 1.2 3.2 0.9 1.4 3.8 3.7 2.7 1.7 3.3 2.3 3.1 3.3 3.4 2.3 1.2 1.9 3.7 3.6 2.9 4.8 1.5 1.2 2.7 3.8 5.2 3.7 3.1 1.4 3.0 2.9 2.9 3.5 2.5 2.9 2.7 3.1 3.2 1.0 4.2 2.8 5.2 1.2 4.9 5.0 1.4 4.6 4.1 2.7 1.2 28.6 13.2 7.1 7.0 9.6 13.6 8.8 14.8 8.4 10.1 9.7 6.4 6.8 19.9 14.6 10.1 14.6 16.1 10.9 12.8 15.0 7.5 7.9 11.9 8.2 4.1 4.2 20.5 5.3 9.8 4.8 9.5 10.3 5.8 11.6 8.7 8.2 7.5 9.6 7.5 13.9 2.6 7.3 15.6 9.6 11.8 12.5 13.5 6.3 11.1 5.2 5.1 28.6 8.3 8.0 7.8 12.0 5.4 14.6 10.5 4.9 12.3 15.2 10.8 7.4 18.5 13.8 6.5 8.5 0.0 0.3 0.0 0.5 0.4 1.0 0.1 0.3 0.5 0.7 0.3 0.4 0.4 0.0 1.3 0.2 0.2 0.4 0.2 0.7 1.1 0.9 1.4 1.2 1.9 1.5 1.2 1.4 1.0 1.2 1.2 11.5 6.4 10.6 39.2 22.4 4.0 7.2 8.8 14.2 14.1 9.2 6.5 7.6 5.7 10.1 3.7 37.5 7.7 14.9 3.5 0.0 5.9 16.4 18.8 18.6 10.2 7.7 14.5 93.0 4.9 3.6 8.3 14.8 10.3 1.3 16.3 7.9 7.3 6.4 8.4 94.4 4.8 14.2 9.4 4.0 8.7 6.5 12.8 10.6 73.1 12.0 6.0 9.2 65.4 71.9 6.4 1.8 7.2 23.1 8.1 1.9 6.5 25.4 23.6 0.0 14.6 9.8 50.1 18.5 14.7 4.5 5.1 15.1 13.8 7.6 6.1 ATRX "JMS, MRX52, RAD54, XH2, XNP" ENSG00000085224 "ATRX chromatin remodeler" P46100 X 77504880-77786233 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001906, CAB009372, HPA064684, CAB068176" Supported Supported "Nuclear bodies" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" "CAB009372: AB_2061023, CAB068176: AB_2665665, HPA001906: AB_1078249, HPA064684: AB_2685321" "unprognostic (1.77e-2)" "unprognostic (1.55e-1)" "unprognostic (6.65e-2)" "unprognostic (4.37e-2)" "unprognostic (1.67e-1)" "unprognostic (9.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.15e-2)" "unprognostic (6.04e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (5.80e-2)" "unprognostic (5.14e-3)" "unprognostic (1.50e-1)" "unprognostic (6.19e-2)" "unprognostic (1.76e-2)" "unprognostic (2.24e-1)" 18.0 15.9 17.3 17.6 20.4 29.9 18.1 32.9 20.4 18.0 21.4 12.7 11.2 21.2 14.8 13.3 11.8 14.7 15.5 19.2 19.8 16.9 13.2 13.4 22.6 15.0 20.1 24.9 13.4 23.2 8.5 16.6 16.6 19.2 13.5 26.8 14.0 14.8 19.1 15.6 10.9 15.6 16.4 22.8 16.5 6.6 22.6 25.7 20.0 26.9 18.6 14.1 9.9 19.7 36.0 55.1 60.1 45.0 31.8 38.1 21.2 29.4 27.3 21.8 25.9 19.6 30.7 48.5 29.9 32.5 39.9 30.0 44.6 18.1 37.5 27.3 30.8 29.3 67.2 16.2 16.1 38.4 10.2 25.5 20.2 32.2 30.4 29.4 41.9 30.3 34.9 53.3 29.3 27.6 30.2 25.0 42.0 17.6 42.5 48.6 76.3 26.0 25.6 46.4 33.1 55.5 60.5 23.1 21.9 37.2 18.6 20.8 55.8 32.8 76.1 34.4 21.0 16.3 52.9 42.1 23.0 30.9 27.8 44.0 10.5 22.7 26.0 13.3 25.2 31.2 24.0 20.9 8.1 32.4 24.6 20.1 33.2 23.2 20.0 20.7 22.2 9.7 17.3 20.4 32.9 20.4 19.2 19.8 15.0 20.1 16.6 16.4 22.6 19.7 201.0 160.3 230.1 157.4 176.6 92.4 112.2 71.3 114.9 220.1 87.8 86.7 277.8 60.1 101.5 71.7 212.7 72.2 176.9 49.0 23.5 91.8 4.7 103.1 195.5 162.8 126.8 105.8 197.8 83.1 51.0 134.3 114.2 137.3 113.1 261.4 97.8 56.7 70.9 158.2 246.9 78.0 69.2 87.0 101.6 12.7 162.4 113.1 62.2 195.8 149.0 112.3 183.4 202.5 237.1 92.0 47.6 208.0 183.9 120.8 49.2 37.2 102.6 245.4 92.1 174.7 160.0 19.8 52.8 78.7 84.4 59.8 158.0 312.4 73.3 112.0 AXIN1 PPP1R49 ENSG00000103126 "Axin 1" O15169 16 287440-352723 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012987 Approved Supported Nucleoli,Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoli, Vesicles" "CAB012987: AB_2533178" "unprognostic (3.81e-2)" "unprognostic (1.56e-1)" "unprognostic (1.90e-1)" "unprognostic (7.64e-2)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (1.23e-1)" "unprognostic (3.58e-1)" "unprognostic (1.56e-1)" "unprognostic (4.58e-2)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" "unprognostic (4.41e-2)" "unprognostic (1.94e-1)" "unprognostic (1.23e-2)" "unprognostic (1.03e-1)" 11.9 9.3 10.5 9.2 10.8 23.0 11.5 14.8 12.5 12.9 9.1 17.1 12.3 13.2 3.1 16.3 11.8 6.2 11.6 10.0 9.2 11.6 11.2 13.7 10.5 10.2 10.2 13.8 13.0 7.2 12.6 5.8 9.8 12.9 6.9 2.6 11.5 6.0 21.1 20.1 15.0 5.4 9.2 15.0 12.9 11.8 10.1 12.5 11.9 7.0 6.6 14.5 13.1 11.9 18.1 25.6 13.4 23.7 9.8 9.0 28.0 11.9 10.8 16.1 13.8 37.9 20.4 27.7 18.0 12.3 19.4 25.4 21.1 18.5 7.2 27.5 34.6 18.0 21.9 27.6 16.6 20.9 19.3 9.0 31.7 16.6 20.3 14.1 10.7 19.8 45.6 14.8 7.4 48.1 22.7 14.5 30.6 21.6 15.4 42.4 12.2 38.8 12.2 10.5 30.4 18.6 22.6 24.9 38.3 10.0 16.5 26.1 12.4 15.9 17.0 18.5 17.5 17.3 18.1 34.2 7.5 13.7 15.9 1.2 0.9 5.0 8.3 0.8 7.6 1.5 2.4 5.8 0.7 1.2 2.4 3.4 2.7 3.5 0.6 1.2 2.6 2.3 10.5 10.8 14.8 12.5 10.0 9.2 10.2 10.2 9.8 9.2 10.1 11.9 7.9 3.2 8.6 4.9 5.7 18.4 7.6 8.5 5.7 4.3 11.2 9.5 4.9 5.7 7.2 3.7 0.0 3.5 30.1 27.4 0.0 7.2 1.4 10.2 7.0 6.3 10.8 8.6 18.5 6.9 27.5 6.7 15.3 14.4 10.8 10.5 5.7 5.1 7.5 5.0 12.7 15.1 6.1 6.2 9.0 2.1 5.3 6.7 10.6 1.0 5.7 4.5 28.8 8.5 8.9 11.0 12.2 4.9 7.0 13.4 11.1 2.4 7.7 5.7 13.1 8.7 7.6 5.5 8.8 7.2 15.2 3.7 12.4 5.0 15.7 10.5 B3GALT6 beta3GalT6 ENSG00000176022 "Beta-1,3-galactosyltransferase 6" Q96L58 1 1232237-1235041 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SCLC-21H: 69.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 14000 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 52: Non-specific - Transcription" "unprognostic (9.76e-2)" "unprognostic (6.97e-2)" "unprognostic (4.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-1)" "unprognostic (4.62e-2)" "unprognostic (2.65e-3)" "unprognostic (1.86e-1)" "unprognostic (1.37e-1)" "unprognostic (2.66e-1)" "unprognostic (3.08e-2)" "unprognostic (2.40e-2)" "unprognostic (1.85e-1)" "unprognostic (1.54e-1)" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (9.89e-2)" 8.7 8.7 8.9 5.6 9.0 1.8 8.4 7.3 9.9 7.6 7.3 6.5 3.9 10.7 3.8 7.2 7.7 3.7 10.1 9.5 10.1 9.9 13.5 6.8 6.2 10.4 9.3 7.0 11.9 7.8 9.3 5.2 8.8 8.0 3.0 2.4 6.4 4.2 9.3 9.2 6.5 4.8 8.3 10.3 7.8 5.4 9.0 5.8 7.7 4.8 3.7 7.6 6.3 9.3 20.4 10.2 17.0 17.9 16.8 11.3 13.2 21.2 17.9 17.4 14.1 9.1 20.3 15.1 12.4 12.7 15.2 17.9 7.4 11.4 10.6 26.8 28.2 28.2 10.1 8.7 17.3 17.6 17.1 10.6 8.3 11.6 11.3 10.5 13.3 17.2 20.0 13.2 18.0 11.6 24.0 31.6 21.9 21.2 37.9 22.8 6.7 12.5 17.4 6.1 69.6 28.6 15.8 18.4 11.4 9.9 15.4 24.9 14.4 17.9 7.9 11.3 30.9 8.2 7.6 14.0 14.1 38.9 20.8 1.3 1.2 0.4 1.6 1.6 2.8 1.4 1.6 1.9 1.7 2.3 1.4 1.7 0.6 2.9 2.0 2.3 0.7 1.0 8.9 9.0 7.3 9.9 9.5 10.1 10.4 9.3 8.8 8.3 9.0 9.3 15.6 12.8 9.9 3.9 13.7 8.4 31.1 3.8 2.2 13.1 15.4 17.5 8.4 11.5 3.4 12.9 4.2 1.7 20.9 3.8 7.9 8.1 0.6 7.6 16.0 12.5 6.0 5.9 3.8 12.7 3.4 10.8 5.1 9.4 0.0 24.7 11.4 13.6 7.3 20.2 5.0 3.7 4.1 12.2 10.3 2.2 2.8 10.5 1.8 1.9 6.9 11.0 18.6 5.5 3.8 11.9 1.0 4.1 9.6 24.5 1.6 10.9 3.0 9.4 0.0 13.6 10.8 1.7 4.1 3.7 12.6 1.4 11.1 33.2 5.3 14.8 B3GLCT "B3GALTL, B3Glc-T, B3GTL" ENSG00000187676 "Beta 3-glucosyltransferase" Q6Y288 13 31199975-31332276 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 59.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (3.31e-2)" "unprognostic (2.53e-1)" "unprognostic (4.71e-2)" "unprognostic (6.17e-3)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" "unprognostic (2.02e-1)" "unprognostic (1.43e-1)" "unprognostic (1.00e-1)" "unprognostic (2.91e-1)" "unprognostic (3.28e-3)" "unprognostic (6.74e-2)" "unprognostic (5.51e-3)" "unprognostic (2.26e-1)" "unprognostic (5.70e-2)" "unprognostic (3.81e-2)" "unprognostic (1.51e-1)" 3.7 2.0 8.6 3.1 11.4 3.9 4.6 6.2 7.8 3.5 12.8 3.1 2.8 12.9 3.9 3.0 6.0 3.5 18.2 8.2 6.9 6.6 3.4 3.7 3.8 6.9 11.2 4.8 3.1 8.1 3.0 7.0 7.1 3.5 3.3 8.0 3.8 6.2 4.7 3.4 2.9 12.7 8.0 3.5 3.4 3.8 13.2 4.9 4.9 2.8 5.6 2.5 3.5 8.0 4.8 6.7 27.1 4.9 5.1 5.1 4.4 11.6 13.0 13.9 9.8 3.5 13.2 19.4 8.3 13.6 26.2 7.9 6.1 7.5 12.9 59.8 11.7 1.3 5.9 5.1 3.2 7.8 10.1 5.9 8.4 8.0 6.8 14.2 12.5 9.5 3.5 3.0 11.0 6.1 11.7 2.4 7.9 7.0 4.1 10.4 8.8 0.6 6.2 6.7 2.5 11.0 10.0 4.7 13.2 6.3 2.3 8.9 17.6 14.0 9.4 6.5 11.7 2.4 5.6 7.3 4.5 5.8 18.9 1.7 0.4 1.3 2.4 0.4 3.5 1.3 1.5 2.7 0.4 0.6 1.2 1.6 0.2 1.4 0.4 0.4 0.9 1.4 8.6 11.4 6.2 7.8 8.2 6.9 6.9 11.2 7.1 8.0 13.2 8.0 4.5 0.0 3.1 0.0 6.6 0.0 3.6 0.0 14.2 10.6 5.1 3.4 23.7 2.8 0.6 9.2 16.7 0.3 7.9 2.5 1.9 4.3 12.1 9.2 5.3 6.5 1.2 1.7 0.0 4.6 2.1 9.0 5.6 4.2 0.0 3.3 8.9 5.5 3.6 0.0 0.0 1.5 0.0 3.2 0.0 2.5 1.5 3.3 0.0 0.0 0.9 5.8 6.2 0.0 0.0 5.6 2.3 3.4 6.4 2.3 2.6 2.6 1.5 4.3 13.1 4.1 5.2 2.1 13.5 7.7 0.0 0.3 6.5 2.3 1.7 1.6 B4GALT7 "beta4Gal-T7, XGALT-1" ENSG00000027847 "Beta-1,4-galactosyltransferase 7" Q9UBV7 5 177600132-177610330 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042330 Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA042330: AB_10796576" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (3.12e-1)" "unprognostic (5.97e-2)" "prognostic unfavorable (2.29e-4)" "unprognostic (9.53e-2)" "unprognostic (4.19e-3)" "unprognostic (3.86e-2)" "unprognostic (1.18e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-3)" "unprognostic (2.00e-2)" "unprognostic (4.81e-2)" "unprognostic (2.39e-1)" "unprognostic (4.44e-2)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" 19.0 43.7 21.1 15.3 20.1 24.8 17.0 20.6 25.5 18.4 21.8 15.1 16.9 20.1 12.5 16.6 16.0 12.5 23.4 20.1 21.8 20.2 30.5 13.4 20.1 24.8 25.1 19.8 37.6 24.3 31.5 14.1 24.8 22.5 11.9 5.9 24.2 18.8 20.2 13.6 14.7 11.8 18.5 21.3 21.8 23.9 22.1 10.6 18.5 10.1 11.8 17.9 13.9 18.7 20.2 34.5 14.2 35.6 28.0 20.7 63.7 30.1 31.9 26.9 30.7 32.6 30.8 25.2 54.7 30.9 47.3 22.9 9.8 64.9 11.7 85.4 25.8 13.3 27.5 23.4 40.0 13.8 22.4 31.8 22.7 29.0 23.5 24.7 30.3 16.9 11.8 23.7 27.4 46.0 11.9 17.1 13.9 17.7 50.0 24.1 10.3 27.8 20.6 29.6 12.5 14.4 15.0 29.8 27.6 11.3 19.4 16.3 23.5 34.0 19.5 22.6 30.6 29.5 14.9 18.4 28.8 33.0 31.8 16.8 16.7 9.7 14.0 19.7 12.6 14.4 12.8 12.2 19.3 18.4 11.4 11.3 1.3 11.1 19.4 15.2 9.2 10.9 21.1 20.1 20.6 25.5 20.1 21.8 24.8 25.1 24.8 18.5 22.1 18.7 16.3 3.2 5.6 5.2 24.5 6.6 15.4 27.8 15.9 12.1 16.5 19.3 6.9 12.8 15.8 16.5 4.2 43.8 16.4 13.8 7.9 34.1 13.9 12.5 17.8 15.6 14.5 8.2 4.3 38.9 132.4 21.2 8.2 13.5 10.2 30.0 10.8 15.9 31.7 11.8 6.0 22.2 8.2 17.8 8.9 9.8 14.0 18.8 21.4 3.7 25.6 13.7 13.4 3.0 3.4 34.0 12.4 18.4 52.8 30.7 17.4 19.6 9.3 16.1 0.0 13.9 16.4 14.3 11.3 13.9 8.8 43.9 12.8 33.4 23.3 16.3 B9D1 "B9, EPPB9, MKS9, MKSR-1" ENSG00000108641 "B9 domain containing 1" Q9UPM9 17 19334308-19378193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 226.2;Endometrial ciliated cells: 99.7;Late spermatids: 171.8;Respiratory ciliated cells: 159.5;Spermatocytes: 141.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022957 Approved "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "HPA022957: AB_1848220" "unprognostic (3.13e-2)" "unprognostic (3.78e-2)" "unprognostic (2.16e-1)" "unprognostic (3.66e-3)" "unprognostic (9.82e-3)" "unprognostic (1.37e-2)" "unprognostic (6.57e-3)" "unprognostic (1.32e-1)" "unprognostic (1.29e-1)" "unprognostic (1.46e-2)" "unprognostic (1.83e-2)" "unprognostic (2.21e-1)" "prognostic favorable (4.14e-4)" "unprognostic (3.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.23e-1)" "unprognostic (1.18e-3)" 7.7 20.9 20.1 3.9 22.0 5.7 12.2 16.5 23.0 14.3 38.1 10.2 6.0 15.4 54.8 9.3 62.7 11.1 13.5 20.7 19.4 26.0 10.4 9.5 3.8 18.9 20.8 15.7 22.1 34.2 60.9 5.1 15.6 11.3 7.5 21.8 11.4 18.1 5.9 7.1 5.3 11.8 17.0 7.4 10.4 65.3 21.0 3.7 39.4 5.4 4.5 8.1 7.9 17.9 66.7 61.2 14.9 20.9 18.8 29.2 18.6 10.9 55.8 35.4 37.5 14.1 17.6 18.0 13.9 21.3 20.6 27.3 11.2 31.6 22.1 6.2 41.0 1.1 30.8 43.8 30.6 4.3 2.9 23.4 24.4 22.2 42.0 50.3 33.2 21.5 10.5 2.0 33.2 57.6 2.1 5.3 10.7 32.0 21.3 11.6 1.6 29.9 74.9 4.5 43.6 10.8 22.8 5.7 15.5 42.7 47.1 7.2 6.4 9.4 23.2 10.4 11.7 11.6 2.3 5.5 23.0 2.4 15.7 0.0 0.6 0.0 0.7 1.8 0.9 2.2 0.5 0.6 0.2 0.4 0.6 0.4 0.0 0.8 1.6 0.3 0.2 1.0 20.1 22.0 16.5 23.0 20.7 19.4 18.9 20.8 15.6 17.0 21.0 17.9 1.5 16.0 11.9 13.4 8.1 3.8 10.7 23.0 13.1 5.8 10.5 13.6 10.9 8.6 19.9 38.6 12.5 4.4 0.7 2.6 64.6 19.8 226.2 99.7 8.1 4.9 20.4 9.0 14.5 14.6 4.8 14.6 12.2 5.9 0.0 9.5 3.3 4.6 5.4 5.0 10.6 12.8 14.2 1.0 1.7 171.8 13.1 2.3 16.0 1.9 1.3 14.0 1.0 10.1 8.2 9.6 2.9 9.8 27.2 11.1 1.3 82.6 159.5 16.6 6.6 7.3 30.8 141.5 26.8 14.2 2.0 2.6 2.1 25.2 7.3 7.0 B9D2 "MGC4093, MKS10, MKSR-2" ENSG00000123810 "B9 domain containing 2" Q9BPU9 19 41354417-41364165 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 64.8;Respiratory ciliated cells: 76.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 127.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042229, HPA042618" Enhanced NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "HPA042229: AB_10959591, HPA042618: AB_10960695" "unprognostic (9.25e-2)" "unprognostic (1.82e-3)" "unprognostic (1.66e-1)" "unprognostic (9.68e-3)" "unprognostic (1.23e-1)" "unprognostic (2.19e-3)" "unprognostic (1.04e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (6.39e-4)" "unprognostic (2.58e-1)" "unprognostic (8.22e-3)" "unprognostic (4.50e-1)" "unprognostic (1.62e-2)" "unprognostic (1.13e-1)" "unprognostic (1.35e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-3)" 4.2 8.5 3.9 4.0 4.2 8.8 4.4 3.7 5.6 5.5 8.1 6.6 3.2 6.5 1.9 4.3 10.5 2.7 4.1 4.3 5.4 9.0 5.0 5.5 3.9 4.0 4.6 3.4 4.5 2.2 5.8 2.1 4.1 5.4 1.8 1.2 4.3 3.6 3.0 3.6 5.1 2.4 4.3 7.8 5.5 8.4 5.5 4.7 5.9 1.5 2.2 5.1 3.8 3.8 6.7 22.0 5.8 5.2 2.1 3.4 1.4 4.2 5.0 7.1 4.4 5.9 5.8 1.7 15.6 5.1 3.0 2.0 3.9 5.8 1.7 6.8 5.9 5.6 7.4 5.1 4.2 7.0 12.6 3.9 4.0 6.3 1.6 4.9 8.0 6.1 4.1 5.9 3.4 5.8 6.5 9.0 2.8 3.1 6.6 5.4 1.3 6.0 6.0 4.3 4.9 4.1 7.3 3.1 3.7 1.1 3.9 12.9 11.9 8.1 3.6 4.3 8.4 2.6 2.4 3.9 8.6 7.4 5.4 47.2 32.3 25.6 10.7 19.8 14.0 15.8 19.7 14.7 22.6 10.3 20.5 14.0 127.5 21.0 16.3 26.1 24.8 18.3 3.9 4.2 3.7 5.6 4.3 5.4 4.0 4.6 4.1 4.3 5.5 3.8 4.0 0.0 9.4 2.0 12.0 4.1 9.8 17.3 5.7 1.6 5.9 3.7 2.0 20.0 17.1 20.2 8.4 8.3 8.0 20.1 37.2 17.4 24.2 64.8 5.6 9.9 15.5 4.8 1.1 16.8 14.9 6.1 8.2 7.6 12.6 4.3 10.0 4.6 13.1 0.0 1.1 13.3 18.3 12.9 4.3 36.7 2.8 8.0 3.6 0.0 8.7 5.4 6.2 0.0 0.6 12.1 37.4 6.4 5.5 7.8 9.9 32.6 76.9 6.1 6.6 9.1 6.8 18.4 12.0 3.9 3.3 6.8 10.3 9.2 10.2 12.6 BCAP31 "6C6-Ag, BAP31, CDM, DXS1357E" ENSG00000185825 "B cell receptor associated protein 31" P51572 X 153700492-153724565 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Deafness, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003906, CAB015350, CAB015424" Supported Approved Enhanced "Endoplasmic reticulum" NA NA 170000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "CAB015350: AB_2243544, CAB015424: AB_781567, HPA003906: AB_1078270" "unprognostic (1.02e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-2)" "unprognostic (3.70e-1)" "unprognostic (2.36e-2)" "prognostic unfavorable (9.87e-4)" "unprognostic (3.25e-3)" "unprognostic (4.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.28e-2)" "unprognostic (8.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" 294.1 213.9 171.5 100.9 175.5 151.3 210.9 171.8 213.9 139.5 202.5 157.7 133.3 127.4 228.9 214.0 151.0 118.0 123.5 183.0 192.1 160.7 185.5 144.5 111.8 190.8 187.5 130.9 266.4 193.7 123.5 143.3 195.3 154.6 166.5 63.9 179.7 177.7 81.9 187.3 143.8 155.0 183.4 138.5 129.3 117.3 186.9 99.7 161.4 75.5 134.6 177.9 145.8 185.0 505.5 482.4 128.0 650.6 593.8 179.1 295.3 269.9 287.5 291.6 371.6 386.8 361.9 315.9 1068.1 412.2 373.9 506.8 337.3 518.6 221.0 152.8 436.9 198.4 350.4 323.3 276.4 335.1 373.2 233.8 454.2 282.3 330.1 298.4 372.6 172.0 268.0 528.3 332.7 535.3 187.3 402.5 145.8 704.6 431.7 207.5 152.8 693.2 459.3 546.8 173.3 241.8 111.8 520.6 350.0 200.3 196.2 320.2 380.0 248.9 234.7 338.9 495.1 518.0 1120.1 397.3 460.9 402.6 223.7 630.5 484.2 489.1 507.5 535.7 454.7 436.1 504.5 507.4 420.7 463.6 439.1 474.7 624.5 449.8 632.3 666.9 457.1 1110.8 171.5 175.5 171.8 213.9 183.0 192.1 190.8 187.5 195.3 183.4 186.9 185.0 184.9 112.2 114.1 14.7 97.5 141.9 232.2 374.0 172.4 53.0 127.3 165.7 60.3 134.4 222.8 128.8 45.9 467.5 113.5 194.1 37.2 252.4 7.8 99.7 70.1 165.5 103.2 59.3 16.9 210.0 444.8 103.6 78.5 103.9 95.6 68.5 199.6 216.0 356.2 32.0 12.8 155.1 244.1 148.4 125.6 20.6 105.3 166.2 160.1 17.8 137.5 138.2 111.2 11.6 12.9 247.1 187.4 98.9 120.8 191.8 242.8 170.9 172.6 51.8 157.8 42.9 106.5 310.3 231.3 174.0 130.4 538.1 114.6 120.4 187.0 260.4 BCOR "FLJ20285, KIAA1575" ENSG00000183337 "BCL6 corepressor" Q6W2J9 X 40049815-40177329 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056308, HPA073591" Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA056308: AB_2683095, HPA073591: AB_2732227" "unprognostic (2.75e-2)" "unprognostic (2.83e-1)" "unprognostic (2.45e-1)" "unprognostic (9.26e-2)" "unprognostic (1.55e-1)" "unprognostic (9.80e-3)" "prognostic unfavorable (1.30e-5)" "unprognostic (3.82e-3)" "unprognostic (6.86e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.91e-3)" "unprognostic (6.83e-2)" "unprognostic (9.57e-2)" "unprognostic (2.63e-1)" "unprognostic (1.55e-1)" 10.2 14.0 2.4 8.3 3.8 22.2 10.0 3.0 3.7 11.5 3.8 14.7 8.8 11.0 5.4 14.4 10.9 7.5 14.0 1.9 2.9 12.9 14.6 12.3 15.0 4.5 3.3 20.0 13.9 14.0 12.0 12.3 2.8 12.5 6.8 14.2 11.9 8.4 20.6 14.7 11.2 8.7 2.0 10.7 12.2 9.0 3.8 25.8 15.6 7.2 12.5 10.9 11.4 5.1 35.5 21.9 45.1 50.5 4.7 3.3 7.8 11.4 18.6 14.4 11.7 8.9 13.5 31.3 13.3 21.7 8.9 31.0 70.8 9.3 12.0 56.0 67.4 36.2 31.8 31.7 7.6 28.7 19.3 5.6 12.0 16.7 7.0 20.0 19.8 20.2 94.7 74.3 14.8 17.9 65.8 27.2 43.4 14.2 33.9 32.3 47.5 36.2 17.3 20.8 32.5 57.6 25.5 20.5 15.5 18.9 22.8 51.5 16.8 15.5 18.5 23.1 12.8 39.1 36.1 33.8 13.1 23.5 24.6 4.6 3.1 2.1 3.8 3.6 2.7 1.9 2.5 2.4 4.5 2.5 2.1 2.3 0.5 3.3 3.9 1.4 2.7 8.8 2.4 3.8 3.0 3.7 1.9 2.9 4.5 3.3 2.8 2.0 3.8 5.1 20.3 22.4 24.5 24.2 16.8 14.7 4.7 8.0 33.6 35.7 10.4 13.1 9.2 10.0 5.9 11.0 12.5 4.5 20.6 6.4 1.9 5.4 2.1 24.1 8.6 15.9 16.3 20.4 21.6 10.5 6.3 11.9 11.7 25.6 24.6 12.8 16.4 10.7 7.5 15.2 20.4 11.4 10.2 8.4 25.6 2.4 10.5 11.5 5.4 27.2 12.0 7.6 7.2 27.6 31.3 6.4 3.9 7.9 16.9 7.6 6.5 4.1 7.1 23.8 0.0 16.4 17.4 2.0 13.2 21.0 13.9 2.1 21.1 6.4 8.8 2.8 BGN "DSPG1, SLRR1A" ENSG00000182492 Biglycan P21810 X 153494980-153509546 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 795.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 223.5;Peritubular cells: 782.7;Sertoli cells: 1485.7;Smooth muscle cells: 401.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 312.6;BJ hTERT+: 400.8;fHDF/TERT166: 568.9;HSkMC: 283.9;hTEC/SVTERT24-B: 235.2;HUVEC TERT2: 561.2;U-138 MG: 249.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003157, CAB003678" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" NA NA 3300000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Endoplasmic reticulum" "CAB003678: AB_425325, HPA003157: AB_1078282" "unprognostic (1.74e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-3)" "unprognostic (3.60e-1)" "unprognostic (5.42e-2)" "unprognostic (3.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.22e-2)" "unprognostic (1.76e-3)" "unprognostic (1.30e-2)" "unprognostic (2.63e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (6.00e-8)" "unprognostic (7.05e-3)" "unprognostic (2.40e-2)" "unprognostic (5.66e-2)" "unprognostic (2.57e-3)" 165.8 213.0 54.1 93.1 57.6 0.3 118.0 51.2 91.5 371.0 69.5 69.3 22.0 234.4 83.7 45.8 143.7 326.1 795.8 56.1 48.7 396.5 347.9 477.3 42.4 50.6 50.8 94.9 67.9 26.6 144.1 199.1 53.2 184.2 24.8 1.1 107.7 135.5 32.4 118.9 48.8 213.2 45.5 352.1 51.6 69.9 64.6 15.9 250.0 46.7 35.9 126.8 180.0 65.4 0.0 0.0 29.7 0.1 31.5 70.5 1.1 312.6 400.8 56.7 18.6 39.5 0.0 0.0 56.9 568.9 2.0 0.1 0.0 0.0 10.2 0.0 0.0 0.0 0.6 3.9 27.0 0.0 0.2 283.9 2.2 235.2 10.7 29.0 561.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.0 1.5 0.3 0.2 0.0 0.1 0.0 0.6 0.4 0.0 0.0 1.1 11.8 1.3 0.0 120.0 249.5 2.3 1.0 1.5 0.9 0.1 0.0 0.1 0.3 114.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 57.6 51.2 91.5 56.1 48.7 50.6 50.8 53.2 45.5 64.6 65.4 30.5 3.2 5.6 5.9 0.6 104.1 1.3 7.3 5.7 0.2 1.2 5.6 16.1 4.3 2.5 9.2 0.0 15.5 0.7 0.0 1.9 2.7 1.8 1.4 28.3 45.2 0.0 5.3 0.1 0.2 50.0 180.0 7.7 1.1 3.8 8.4 223.5 1.6 4.4 3.3 0.1 0.0 0.0 4.0 43.6 13.5 147.9 3.0 35.6 25.3 2.0 0.1 0.0 20.6 0.0 1.2 0.0 782.7 0.0 3.0 0.0 0.8 1.6 0.2 1485.7 3.1 401.3 0.8 1.2 1.8 54.1 56.9 3.0 7.7 0.0 1.6 BHLHA9 BHLHF42 ENSG00000205899 "Basic helix-loop-helix family member a9" Q7RTU4 17 1270444-1271815 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "brain: 1.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 65: Brain - Ion transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (9.27e-2)" "unprognostic (2.63e-1)" "unprognostic (2.99e-1)" "unprognostic (7.74e-2)" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.6 0.4 0.2 1.0 0.0 1.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BLM "BS, RECQ2, RECQL3" ENSG00000197299 "BLM RecQ like helicase" P54132 15 90717346-90816166 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.7;lymphoid tissue: 7.9;salivary gland: 7.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 18.3;Oligodendrocyte precursor cells: 58.3;Plasma cells: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005689 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA005689: AB_1845372" "unprognostic (2.77e-1)" "unprognostic (3.82e-3)" "unprognostic (4.03e-2)" "unprognostic (2.98e-2)" "unprognostic (4.75e-2)" "unprognostic (9.89e-2)" "unprognostic (6.12e-5)" "unprognostic (2.82e-2)" "unprognostic (4.55e-3)" "unprognostic (5.24e-3)" "unprognostic (1.80e-3)" "unprognostic (9.12e-2)" "unprognostic (1.55e-15)" "unprognostic (6.53e-3)" "unprognostic (6.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" 0.3 0.2 0.9 3.6 1.1 5.7 0.5 2.3 0.9 0.1 0.3 1.4 1.0 0.4 0.4 0.6 0.3 0.3 0.3 0.8 1.1 0.1 0.1 0.4 6.4 1.2 1.4 0.1 0.2 0.0 0.6 1.2 1.1 0.1 1.7 2.4 7.8 0.0 0.5 0.4 1.6 0.4 1.0 1.6 1.1 2.2 0.9 7.9 0.3 0.1 6.2 1.0 0.2 1.0 13.0 14.4 20.4 12.6 0.1 0.9 14.6 9.4 3.2 11.1 13.4 11.7 10.1 35.1 5.9 2.6 14.1 20.4 25.7 7.1 15.1 19.1 20.5 36.4 14.8 3.9 0.0 33.7 17.3 0.3 0.1 10.6 4.7 1.3 7.9 16.9 32.7 9.9 11.0 7.4 28.3 14.5 22.2 24.9 4.2 25.4 39.1 14.7 2.3 18.9 14.6 14.7 8.5 11.5 4.8 18.1 7.2 23.4 3.7 8.6 13.6 9.6 21.0 6.4 30.4 39.5 5.6 25.8 15.7 1.7 0.6 2.6 1.6 0.8 2.6 4.6 1.4 2.1 0.7 2.3 1.0 1.1 0.7 3.1 1.0 0.7 3.2 0.9 0.9 1.1 2.3 0.9 0.8 1.1 1.2 1.4 1.1 1.0 0.9 1.0 0.9 3.2 8.9 1.0 12.9 0.3 0.5 0.5 0.6 3.6 1.3 1.0 7.9 0.0 4.2 0.0 2.1 5.5 6.9 2.2 1.9 1.0 2.7 1.3 1.3 2.0 0.0 18.3 0.7 0.7 6.8 1.8 3.6 1.7 13.3 8.1 2.2 0.6 5.7 0.0 8.6 1.3 0.0 7.7 1.3 1.6 0.0 7.7 0.0 7.5 2.7 1.7 10.3 58.3 2.6 1.2 0.3 0.4 20.6 0.7 0.2 0.0 5.4 7.1 0.0 0.9 1.7 17.1 12.9 2.2 0.6 1.0 10.2 0.7 4.0 0.4 BMP1 "BMP-1, PCOLC" ENSG00000168487 "Bone morphogenetic protein 1" P13497 8 22165140-22212326 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor, Hydrolase, Metalloprotease, Protease" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 69.3;Endometrial stromal cells: 52.8;Smooth muscle cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014572 Enhanced "Secreted to extracellular matrix" NA NA 9200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA014572: AB_1845390" "unprognostic (1.24e-1)" "unprognostic (8.01e-2)" "unprognostic (3.75e-2)" "unprognostic (5.89e-2)" "unprognostic (1.34e-2)" "unprognostic (6.76e-2)" "unprognostic (9.53e-2)" "unprognostic (2.64e-3)" "unprognostic (1.66e-1)" "unprognostic (9.75e-3)" "unprognostic (7.05e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (3.37e-9)" "unprognostic (2.11e-2)" "unprognostic (6.57e-2)" "unprognostic (1.50e-3)" "unprognostic (3.34e-2)" 11.7 17.4 3.8 6.3 4.6 1.4 9.0 4.7 4.4 15.6 4.9 8.1 4.8 12.7 3.9 7.0 11.8 9.8 5.9 4.3 3.9 7.7 14.7 8.3 1.7 5.0 4.1 5.9 4.4 3.4 3.4 27.3 4.1 9.6 5.3 0.6 3.7 6.1 3.4 6.2 5.9 14.4 4.3 5.0 4.3 2.4 4.2 1.5 10.0 3.1 1.8 10.4 10.3 4.4 15.2 20.4 7.4 30.2 47.8 41.8 23.2 54.1 50.1 33.8 27.6 5.1 27.4 3.7 32.0 56.9 18.9 51.2 5.1 27.8 6.5 3.6 6.9 6.7 24.5 7.9 31.7 2.9 14.3 49.8 26.5 25.2 11.4 78.3 31.4 5.2 7.1 10.6 19.6 4.6 1.4 3.0 4.7 17.0 8.3 6.4 8.2 15.2 26.7 4.1 2.8 10.6 52.5 3.1 13.4 20.4 5.0 8.3 41.4 17.0 18.4 32.3 23.9 4.0 2.2 0.6 23.8 10.1 28.0 0.0 0.4 0.0 0.6 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.2 0.0 0.1 3.8 4.6 4.7 4.4 4.3 3.9 5.0 4.1 4.1 4.3 4.2 4.4 12.5 6.4 69.3 5.5 0.8 6.2 5.2 22.6 4.0 2.6 5.0 6.1 4.9 2.8 6.7 5.5 0.0 3.3 3.2 31.9 0.0 25.1 0.7 3.1 52.8 14.1 3.0 0.8 3.5 8.2 9.5 28.7 1.1 5.7 15.2 13.9 14.6 20.1 4.3 1.7 2.7 6.2 0.0 3.4 6.1 1.1 10.2 5.4 10.6 4.7 1.0 2.2 3.1 6.6 6.7 15.3 18.6 10.9 2.8 4.7 13.2 4.1 2.2 1.1 26.3 6.4 43.7 1.5 4.0 6.5 5.3 24.4 3.3 34.2 10.7 8.0 BMP2 BMP2A ENSG00000125845 "Bone morphogenetic protein 2" P12643 20 6767686-6780246 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal keratinocytes: 167.1;Distal enterocytes: 125.6;Suprabasal keratinocytes: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 31.6;HeLa: 19.6;hTERT-HME1: 17.8;RT4: 25.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA058610, CAB078457" Enhanced Vesicles "Secreted to blood" NA NA 24400 21000 "Cluster 19: Lung - Lung function" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB078457: AB_2532532, HPA058610: AB_2683777" "unprognostic (2.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.12e-2)" "unprognostic (3.56e-2)" "unprognostic (1.94e-2)" "unprognostic (2.48e-1)" "unprognostic (3.70e-3)" "unprognostic (3.12e-3)" "unprognostic (8.51e-2)" "unprognostic (8.46e-2)" "unprognostic (2.53e-3)" "unprognostic (5.39e-3)" "unprognostic (7.81e-2)" "unprognostic (3.76e-1)" "unprognostic (2.77e-1)" "unprognostic (3.01e-2)" "unprognostic (7.49e-2)" 18.6 1.6 1.2 4.0 1.5 1.6 6.0 1.3 1.6 5.2 0.9 15.1 6.6 5.2 0.6 5.5 3.8 16.1 4.0 1.8 1.4 3.9 5.8 18.8 1.9 1.9 2.2 2.8 9.2 3.2 2.3 11.5 2.1 1.9 13.6 1.3 2.1 1.2 2.2 10.6 9.7 2.6 1.5 12.4 20.7 0.5 2.1 0.4 18.9 2.7 1.8 17.2 6.4 2.2 0.1 0.3 0.0 0.0 0.5 0.2 0.0 0.8 3.4 0.0 0.0 31.6 0.1 0.0 0.5 1.1 0.0 10.5 6.2 2.7 0.0 0.0 5.5 0.0 19.6 0.1 1.5 0.0 0.8 0.2 9.2 0.0 17.8 4.0 6.3 0.0 0.0 0.0 0.2 0.0 0.0 6.0 0.8 3.7 0.8 6.2 0.1 0.4 2.3 25.0 1.1 1.6 7.3 0.0 0.0 5.5 0.0 6.5 1.5 1.8 2.7 0.0 0.9 0.3 0.9 0.0 3.0 1.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 1.5 1.3 1.6 1.8 1.4 1.9 2.2 2.1 1.5 2.1 2.2 9.4 80.1 155.9 0.3 1.1 167.1 45.1 11.0 70.0 0.4 1.4 2.2 4.7 42.9 10.5 1.8 0.0 0.1 3.8 125.6 0.0 23.3 0.3 1.7 34.8 24.1 11.3 0.0 1.1 9.8 0.2 20.2 33.6 3.0 8.8 1.9 41.4 3.4 3.6 0.0 3.5 23.8 0.0 2.9 16.8 0.2 5.9 2.9 8.8 2.8 0.6 6.2 0.0 8.5 1.4 33.5 60.3 0.0 1.3 47.5 28.3 2.1 0.8 0.2 19.7 36.5 48.8 0.0 0.3 43.1 119.3 0.1 2.1 4.3 48.2 43.3 BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 47.3;Fibroblasts: 65.2;Hepatic stellate cells: 52.8;Pancreatic endocrine cells: 40.1;Skeletal myocytes: 51.0;Syncytiotrophoblasts: 34.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 120.1;CAPAN-2: 298.6;Hep G2: 326.0;OE19: 219.1;SuSa: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" NA NA 162000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" 14.0 13.4 3.0 6.1 3.2 0.1 13.4 7.0 4.5 21.0 32.4 25.6 17.0 8.9 2.5 12.9 9.7 14.4 16.3 3.1 2.8 9.0 4.2 13.4 9.6 3.6 3.3 23.8 3.4 2.7 4.7 44.4 3.9 21.9 28.9 2.7 10.5 18.7 11.5 15.3 19.2 9.0 3.2 6.5 23.8 2.0 3.9 3.4 8.5 17.7 4.2 27.4 23.5 4.7 15.6 40.0 2.1 1.8 0.5 0.4 0.6 7.9 34.0 20.1 15.5 120.1 298.6 0.0 97.2 0.1 2.2 73.2 8.6 1.0 10.7 4.1 5.9 0.2 8.3 326.0 19.4 0.0 1.0 0.0 2.8 9.5 0.5 61.1 59.3 6.8 0.0 0.3 9.7 6.9 5.3 0.3 13.9 219.1 3.4 0.2 10.5 0.3 28.5 1.3 0.1 0.3 0.0 1.1 0.9 168.2 38.8 1.5 2.9 0.6 87.1 0.3 1.4 0.2 0.1 1.0 0.1 0.1 4.3 0.0 0.6 0.0 0.1 1.1 0.0 0.0 0.9 0.2 0.1 0.0 1.3 0.4 0.0 0.0 1.9 0.0 0.0 0.3 3.0 3.2 7.0 4.5 3.1 2.8 3.6 3.3 3.9 3.2 3.9 4.7 7.6 9.6 7.3 1.0 0.6 27.5 4.0 16.1 47.3 0.3 8.0 10.4 5.7 14.3 6.0 5.5 0.0 29.3 0.1 1.0 3.9 5.5 2.5 0.7 18.9 18.2 0.0 2.7 1.3 0.2 18.9 65.2 0.5 0.7 1.3 0.9 52.8 2.0 3.7 0.0 0.4 5.3 2.0 0.6 5.9 1.0 10.5 0.4 3.6 1.9 0.0 0.5 0.0 1.0 0.3 40.1 4.0 1.5 0.1 2.3 0.6 2.4 5.8 1.5 0.0 51.0 10.5 1.4 2.2 7.5 17.5 34.8 1.0 1.4 4.0 1.4 BMPER "CRIM3, Cv2" ENSG00000164619 "BMP binding endothelial regulator" Q8N8U9 7 33904308-34156427 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Excitatory neurons: 286.9;Hepatic stellate cells: 117.8;Inhibitory neurons: 90.1;Oligodendrocyte precursor cells: 105.1" "Cancer enhanced" "Detected in some" "glioma: 2.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 14.5;fHDF/TERT166: 17.0;HBF TERT88: 17.2;HSkMC: 15.5;hTEC/SVTERT24-B: 14.9;U-138 MG: 22.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.50e-2)" "unprognostic (2.68e-1)" "unprognostic (2.83e-2)" "unprognostic (3.19e-2)" "unprognostic (1.93e-1)" "unprognostic (1.96e-4)" "unprognostic (5.34e-3)" "unprognostic (3.10e-1)" "unprognostic (9.98e-3)" "unprognostic (3.50e-3)" "unprognostic (8.01e-4)" "unprognostic (1.96e-1)" "unprognostic (5.67e-5)" "unprognostic (2.54e-1)" "unprognostic (2.62e-1)" "unprognostic (2.06e-2)" "unprognostic (3.47e-3)" 3.1 0.5 0.7 3.9 0.9 0.0 1.8 1.4 1.5 3.8 0.0 1.2 0.6 1.6 2.2 0.6 1.3 0.8 1.5 0.9 0.3 0.2 5.1 5.1 0.5 0.6 0.4 2.1 0.1 0.1 1.7 5.5 0.9 3.5 0.8 0.3 0.8 0.2 1.8 0.2 2.3 1.0 0.5 0.2 4.0 0.4 0.3 0.3 0.4 3.7 0.0 1.5 1.4 0.8 0.0 0.6 0.0 0.0 14.5 7.9 0.0 10.8 4.1 8.1 6.9 0.0 0.0 0.0 0.0 17.0 4.1 6.3 0.0 0.0 17.2 0.0 0.4 0.0 0.0 0.0 1.6 0.0 0.0 15.5 0.0 14.9 0.1 0.8 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 2.1 0.8 0.0 0.0 22.5 1.1 9.2 0.0 0.7 0.0 0.0 8.4 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 1.4 1.5 0.9 0.3 0.6 0.4 0.9 0.5 0.3 0.8 1.1 0.0 0.0 29.0 0.2 0.0 0.6 0.3 0.0 0.4 0.2 0.0 4.6 0.0 0.0 0.0 6.2 0.5 0.0 0.0 0.0 0.1 1.9 0.2 3.2 1.3 4.2 2.7 286.9 0.0 0.5 14.3 0.0 0.4 0.0 1.5 117.8 0.3 0.1 0.0 90.1 0.1 0.0 2.8 0.0 1.0 0.0 0.3 0.0 18.7 0.0 0.2 0.0 105.1 9.8 0.0 0.0 1.2 0.0 1.1 0.0 0.0 0.0 0.5 0.0 5.0 2.1 1.3 5.8 0.1 0.1 0.1 0.2 0.3 0.1 0.3 BMPR1B "ALK6, CDw293" ENSG00000138696 "Bone morphogenetic protein receptor type 1B" O00238 4 94757955-95158448 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chondrogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1;cervix: 24.7;prostate: 22.4" "Cell type enriched" "Detected in many" 7 "Astrocytes: 480.6" "Cancer enhanced" "Detected in many" "breast cancer: 32.4;prostate cancer: 24.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 22.0;MCF7: 11.1;SH-SY5Y: 18.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.40e-3)" "prognostic favorable (2.84e-4)" "unprognostic (1.57e-1)" "unprognostic (4.22e-2)" "unprognostic (1.92e-1)" "unprognostic (2.86e-2)" "unprognostic (2.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.97e-2)" "unprognostic (3.93e-1)" "unprognostic (1.62e-3)" "unprognostic (7.89e-4)" "unprognostic (6.22e-2)" "unprognostic (3.81e-3)" "unprognostic (2.63e-2)" 0.7 4.6 13.4 0.3 15.4 0.1 1.0 13.5 15.0 24.7 2.1 0.9 0.1 4.4 2.4 0.2 12.5 2.6 0.8 12.5 16.0 7.8 0.8 1.7 0.0 19.3 20.1 6.2 1.1 0.1 1.9 0.7 17.5 22.4 0.2 8.1 1.0 14.2 3.0 0.8 0.1 0.6 15.3 0.9 2.4 3.7 15.6 6.4 0.5 1.1 0.0 0.2 0.5 12.1 0.0 22.0 5.6 0.0 2.3 4.8 0.2 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.2 1.0 0.0 1.3 3.6 8.4 0.1 0.0 4.9 0.0 1.4 0.0 0.6 0.5 0.1 2.7 9.0 2.8 6.2 0.4 0.1 0.0 0.0 0.0 7.1 11.1 0.6 0.1 2.1 0.1 3.2 0.2 3.4 0.1 4.3 0.1 0.2 18.8 0.3 3.2 3.2 0.8 1.7 0.0 0.0 4.0 3.8 0.2 4.3 0.0 0.0 0.0 1.5 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 13.4 15.4 13.5 15.0 12.5 16.0 19.3 20.1 17.5 15.3 15.6 12.1 0.0 6.4 0.0 480.6 0.0 2.7 1.3 13.1 1.2 0.4 3.8 1.0 3.4 2.8 33.4 60.7 0.0 0.0 0.0 0.0 1.9 3.0 1.4 28.5 1.4 1.1 18.4 0.0 51.0 0.4 0.3 1.5 0.0 20.8 0.0 38.6 2.9 0.0 0.1 0.0 2.5 0.0 8.2 0.0 1.2 1.4 3.1 0.4 28.4 22.5 0.0 38.5 0.0 10.1 2.8 0.7 0.0 3.8 0.0 28.5 0.0 0.2 15.7 1.6 0.0 1.7 2.9 1.2 10.6 0.4 2.3 0.0 0.5 4.4 0.0 1.6 BMS1 "BMS1L, KIAA0187" ENSG00000165733 "BMS1 ribosome biogenesis factor" Q14692 10 42782795-42834937 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036589, HPA043081" Uncertain Enhanced "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Mitotic chromosome" "HPA036589: AB_10601460, HPA043081: AB_2678305" "unprognostic (1.46e-2)" "unprognostic (4.31e-1)" "unprognostic (7.09e-2)" "unprognostic (3.56e-2)" "unprognostic (3.11e-2)" "unprognostic (7.25e-3)" "prognostic unfavorable (1.06e-6)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" "unprognostic (1.89e-2)" "unprognostic (3.81e-3)" "unprognostic (1.32e-2)" "unprognostic (2.16e-3)" "unprognostic (7.03e-2)" "unprognostic (1.80e-1)" "unprognostic (3.43e-1)" "unprognostic (4.82e-2)" 8.1 8.3 6.5 8.9 7.2 10.7 8.5 8.6 8.2 8.2 8.5 7.7 6.3 8.2 6.8 9.6 7.3 5.1 9.0 6.1 7.8 8.1 8.1 7.6 10.0 7.4 7.8 8.4 8.8 11.4 7.6 8.2 7.7 7.3 7.9 6.5 8.8 6.9 17.7 10.2 7.8 7.7 6.5 8.7 7.4 8.1 7.0 9.6 7.2 13.4 10.8 10.1 8.3 7.2 32.0 26.7 25.3 29.0 18.8 15.5 24.5 26.1 27.5 30.3 25.9 37.1 24.4 16.9 18.1 22.7 17.0 27.3 42.0 33.8 39.4 24.7 29.3 22.7 20.7 31.9 16.2 61.7 20.4 13.9 16.9 32.7 31.5 16.9 23.2 19.4 40.4 17.7 21.8 27.1 34.6 20.3 32.3 22.0 28.0 31.3 26.7 18.1 16.8 27.7 19.3 20.4 22.9 25.1 21.7 26.2 30.6 17.6 28.3 14.0 50.7 28.4 43.2 14.1 18.7 48.5 20.5 44.9 11.0 3.8 4.6 2.7 7.2 8.2 8.5 8.7 8.9 7.9 7.5 6.1 9.6 8.3 0.6 6.1 7.1 3.9 6.9 5.3 6.5 7.2 8.6 8.2 6.1 7.8 7.4 7.8 7.7 6.5 7.0 7.2 25.6 32.1 33.1 19.6 29.7 22.9 33.9 28.4 14.2 20.7 18.8 17.1 48.0 20.0 37.4 23.9 10.4 27.7 23.6 10.2 21.5 32.3 14.6 28.8 34.5 31.3 16.8 19.5 31.4 34.9 30.0 26.4 16.3 30.0 22.1 36.8 21.4 18.6 19.7 21.9 28.8 11.5 22.4 15.3 22.6 12.1 23.6 19.9 33.8 10.3 35.2 12.8 24.7 20.1 24.0 38.2 8.9 16.6 31.3 32.2 8.8 30.1 49.5 28.7 19.7 35.3 31.4 40.3 56.1 17.1 25.4 24.9 25.3 33.5 18.7 41.4 BPNT2 "FLJ20421, gPAPP, IMPA3, IMPAD1" ENSG00000104331 "3'(2'), 5'-bisphosphate nucleotidase 2" Q9NX62 8 56957931-56993867 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 22.6;Cardiomyocytes: 53.8;Cytotrophoblasts: 18.0;dendritic cells: 16.2;Extravillous trophoblasts: 91.8;Hofbauer cells: 26.6;Syncytiotrophoblasts: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009411 Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 480000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA009411: AB_1079138" "unprognostic (1.62e-2)" "unprognostic (7.89e-3)" "unprognostic (6.58e-2)" "unprognostic (6.42e-2)" "unprognostic (2.00e-1)" "unprognostic (8.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.67e-2)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (4.24e-3)" "unprognostic (1.41e-1)" "unprognostic (1.43e-2)" "unprognostic (1.68e-3)" "unprognostic (2.89e-1)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" 37.6 37.3 14.8 16.1 19.9 12.4 19.3 19.2 19.8 25.5 8.9 17.4 13.3 21.9 16.2 19.1 13.4 16.5 29.4 16.0 17.9 23.4 36.2 17.2 12.3 17.2 17.6 11.8 19.6 35.6 13.7 24.9 17.7 31.0 17.6 19.7 21.9 23.6 37.4 14.3 12.7 25.7 15.3 15.5 16.9 16.5 18.0 15.4 27.1 30.1 13.3 22.4 12.2 29.3 42.4 34.5 26.0 26.9 78.2 53.3 35.7 62.9 60.9 44.1 38.3 17.4 29.2 26.3 47.0 67.3 31.2 33.7 31.8 42.5 65.0 36.4 22.7 51.4 23.0 31.2 48.5 33.0 35.1 43.2 41.6 39.7 63.9 40.8 59.5 24.3 22.5 46.1 48.9 22.1 40.6 19.8 19.2 48.1 12.7 27.9 23.4 29.7 46.0 24.9 10.1 28.1 35.3 42.9 36.3 27.1 38.4 23.9 50.1 59.3 34.2 59.2 45.8 47.5 42.5 27.8 81.0 27.0 37.3 1.8 0.9 0.5 0.9 0.6 0.7 0.7 0.6 0.5 0.7 0.9 0.6 1.1 2.5 3.2 2.6 1.0 0.4 0.3 14.8 19.9 19.2 19.8 16.0 17.9 17.2 17.6 17.7 15.3 18.0 29.3 22.6 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.8 0.0 0.0 0.0 0.0 18.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 91.8 14.4 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 33.8 1.8 0.0 0.0 0.0 BRAF BRAF1 ENSG00000157764 "B-Raf proto-oncogene, serine/threonine kinase" P15056 7 140719327-140924929 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 252.3;Inhibitory neurons: 242.4;Oligodendrocyte precursor cells: 206.1;Oligodendrocytes: 202.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001328, CAB004552, HPA071048" Approved Approved Vesicles,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Vesicles Cytosol "CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: AB_2686336" "unprognostic (2.98e-3)" "unprognostic (5.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.66e-3)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.07e-2)" "unprognostic (4.23e-2)" "unprognostic (4.07e-2)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (1.91e-2)" "unprognostic (3.79e-3)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "unprognostic (8.01e-2)" "unprognostic (5.46e-2)" 8.8 5.8 6.3 5.6 7.7 15.9 8.8 12.5 8.7 8.2 5.4 8.6 4.7 8.3 8.3 7.5 8.0 5.8 7.6 8.3 6.7 7.6 6.6 9.9 6.9 4.0 3.6 9.8 8.3 11.5 9.0 7.2 4.6 8.2 5.4 17.0 7.2 5.9 8.6 10.4 6.9 6.0 3.1 6.7 7.8 13.7 5.2 8.7 10.2 8.4 6.4 9.9 8.5 6.7 6.3 5.2 7.7 9.4 9.1 11.8 12.3 6.8 7.5 5.4 7.6 5.7 6.7 10.8 5.0 7.3 8.4 3.4 6.8 5.5 10.0 9.8 5.4 7.1 5.1 5.2 7.6 11.7 6.8 7.9 6.1 6.0 12.0 8.2 6.6 7.7 11.3 19.1 9.8 3.3 15.6 12.0 6.9 6.2 3.1 10.1 6.5 8.9 5.3 11.9 8.9 7.3 7.9 4.9 7.3 7.5 4.5 7.8 9.7 5.9 4.3 12.9 5.5 21.6 12.9 16.7 9.7 11.3 6.6 1.9 1.0 4.1 1.5 0.9 1.0 1.3 1.5 1.2 0.8 1.1 2.6 1.3 2.0 3.5 1.3 1.0 1.5 0.6 6.3 7.7 12.5 8.7 8.3 6.7 4.0 3.6 4.6 3.1 5.2 6.7 43.4 22.4 45.7 151.1 58.4 21.5 24.6 6.0 23.3 29.7 31.2 21.2 19.8 10.0 18.7 25.8 35.5 15.7 73.5 8.8 7.9 14.3 68.6 50.6 37.4 23.4 19.2 14.9 252.3 9.8 12.9 22.0 21.9 69.2 24.7 45.5 9.3 9.6 9.4 25.2 242.4 9.8 8.2 13.6 37.1 36.5 16.4 30.1 16.0 126.5 14.6 11.3 15.5 206.1 202.6 15.4 8.1 10.1 48.7 23.8 8.0 13.4 20.0 33.0 6.6 24.1 24.7 43.8 26.0 14.5 24.0 75.5 41.4 30.9 8.7 33.4 BRAT1 "BAAT1, C7orf27, MGC22916" ENSG00000106009 "BRCA1 associated ATM activator 1" Q6PJG6 7 2537810-2555694 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029455, HPA076508" Approved Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA029455: AB_10600761, HPA076508: AB_2686803" "unprognostic (2.53e-1)" "unprognostic (2.24e-1)" "unprognostic (1.19e-2)" "unprognostic (7.04e-3)" "unprognostic (6.07e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (8.02e-4)" "unprognostic (2.03e-1)" "unprognostic (1.76e-1)" "unprognostic (2.46e-1)" "unprognostic (1.10e-3)" "unprognostic (4.69e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (5.37e-2)" "unprognostic (3.12e-2)" "unprognostic (8.88e-2)" "unprognostic (3.71e-2)" 17.4 31.0 10.7 6.8 10.9 7.9 17.8 10.4 14.3 22.5 9.6 16.2 8.8 19.4 2.2 15.1 19.2 3.7 14.5 10.4 11.2 15.2 20.7 12.2 7.2 13.5 11.4 21.6 20.2 5.2 19.8 4.5 10.1 24.5 1.3 0.9 17.4 6.6 14.8 21.6 16.6 2.5 10.6 21.1 19.6 31.5 11.2 5.0 18.7 3.7 2.1 17.6 18.8 10.5 35.1 31.1 7.5 27.2 6.8 6.3 24.5 11.7 6.5 10.1 8.5 22.5 21.5 26.3 18.1 7.8 19.4 35.1 8.8 13.7 1.6 10.4 44.4 12.2 23.5 14.3 8.7 16.5 18.2 10.6 9.5 10.2 3.0 5.8 11.4 20.2 39.1 9.6 7.1 50.0 11.8 77.9 35.3 8.8 47.0 28.6 21.9 25.5 6.5 11.3 19.5 30.2 17.1 29.8 12.9 3.5 26.5 33.4 11.8 13.8 43.3 28.5 23.2 20.7 17.3 19.0 15.2 32.8 33.2 5.1 30.8 17.5 21.9 28.2 19.3 18.6 19.8 22.6 32.4 15.2 16.3 17.9 25.4 15.9 27.1 22.7 18.4 22.8 10.7 10.9 10.4 14.3 10.4 11.2 13.5 11.4 10.1 10.6 11.2 10.5 10.1 12.8 6.4 19.9 11.1 7.8 17.5 22.6 16.5 12.8 11.3 8.9 6.8 15.7 14.8 9.2 12.5 21.1 15.0 14.8 15.6 10.6 20.8 7.1 12.3 13.0 11.4 10.3 14.2 13.8 12.9 12.8 26.0 7.5 14.0 34.9 15.4 15.3 34.2 3.3 16.2 14.8 8.2 13.1 6.7 9.4 22.7 13.3 7.2 12.2 17.6 14.4 9.2 13.6 11.3 12.0 12.1 22.2 14.4 9.1 15.0 16.6 8.1 11.9 6.6 9.4 10.7 28.8 39.5 8.0 6.8 14.6 11.9 31.7 17.9 7.6 BRF1 "BRF, GTF3B, hBRF, TAF3B2, TAF3C, TFIIIB90" ENSG00000185024 "BRF1 RNA polymerase III transcription initiation factor subunit" Q92994 14 105209286-105315589 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051918, HPA074990" Approved Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies" "HPA051918: AB_2681663, HPA074990: " "unprognostic (1.98e-1)" "unprognostic (4.45e-2)" "unprognostic (1.46e-2)" "unprognostic (2.51e-2)" "unprognostic (1.07e-1)" "unprognostic (7.52e-2)" "unprognostic (1.52e-4)" "unprognostic (2.67e-2)" "unprognostic (3.25e-1)" "unprognostic (2.26e-1)" "prognostic favorable (7.25e-6)" "unprognostic (8.83e-2)" "prognostic favorable (1.13e-4)" "unprognostic (1.85e-1)" "unprognostic (2.70e-1)" "unprognostic (5.39e-2)" "unprognostic (2.52e-1)" 10.5 11.4 19.7 5.5 22.2 6.5 10.5 23.1 23.6 12.5 12.9 11.1 7.6 12.1 4.2 10.4 12.8 6.0 12.2 17.1 19.2 11.6 13.1 8.4 8.1 31.8 24.9 13.0 15.1 10.3 20.4 6.0 29.7 12.0 4.2 7.5 10.1 6.3 17.7 11.2 10.3 4.6 18.7 12.6 11.2 14.6 25.4 7.3 10.5 9.6 5.8 11.5 9.9 37.4 12.6 28.0 11.8 25.3 10.3 11.4 11.9 17.4 11.2 15.4 12.2 20.2 18.8 9.4 16.9 12.0 7.5 24.2 14.4 11.7 8.4 25.2 14.2 11.5 15.1 9.9 11.5 13.7 24.3 11.3 10.1 9.3 11.5 7.8 11.3 19.7 13.1 7.5 7.6 40.9 16.2 17.1 8.6 20.7 27.7 28.2 8.1 9.6 7.6 29.9 37.5 27.8 18.4 14.0 16.0 5.4 33.4 18.9 16.8 12.1 9.6 22.7 14.2 13.8 11.5 8.9 14.5 11.3 16.9 0.4 1.2 2.0 1.6 1.0 1.1 1.5 1.1 1.6 1.2 1.4 1.4 1.3 0.5 2.5 4.0 3.1 1.6 1.6 19.7 22.2 23.1 23.6 17.1 19.2 31.8 24.9 29.7 18.7 25.4 37.4 11.5 3.2 5.9 17.6 11.4 7.5 7.1 4.5 8.6 18.8 10.7 9.0 8.5 2.8 6.3 3.7 16.7 11.4 15.5 16.2 3.9 5.8 2.3 26.5 10.9 9.5 9.6 6.3 18.3 7.1 8.9 7.7 14.8 16.5 2.5 16.0 8.9 11.3 7.2 30.3 20.8 11.7 4.1 6.7 10.3 1.4 6.5 7.8 8.8 10.3 5.3 7.1 4.1 15.1 34.2 4.8 6.5 4.5 13.4 7.7 8.9 6.1 12.4 20.0 0.0 9.6 8.2 9.2 12.7 7.7 8.8 9.3 11.6 13.2 12.5 5.1 C1R ENSG00000159403 "Complement C1r" 12 7080214-7092540 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "liver: 1425.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 442.3;Fibroblasts: 684.4;Hepatocytes: 1444.2;Leydig cells: 1142.6;Peritubular cells: 388.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1089.8;ASC TERT1: 546.0;BJ hTERT+: 461.9;BJ hTERT+ SV40 Large T+ RasG12V: 303.4;HSkMC: 672.1" "Low region specificity" "Detected in many" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001251: AB_2666252, HPA001551: AB_10754818" "unprognostic (1.55e-2)" "unprognostic (8.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (2.66e-2)" "unprognostic (1.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (1.94e-14)" "unprognostic (3.54e-2)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" 540.6 203.6 15.8 122.4 15.9 1.1 400.6 15.9 23.3 470.5 21.7 277.3 38.3 353.8 80.8 119.0 526.3 279.1 458.7 15.4 19.6 148.9 1425.6 340.3 72.4 23.4 19.9 644.3 88.0 11.0 63.9 52.4 18.4 205.2 100.9 5.8 158.3 87.0 69.4 177.7 228.1 157.7 18.1 192.1 242.7 46.7 18.1 34.7 223.4 74.2 75.3 468.4 394.3 18.0 1.2 8.9 0.9 9.1 1089.8 546.0 0.4 108.9 461.9 143.0 303.4 1.4 2.4 0.5 4.5 108.8 11.8 2.3 11.8 5.5 18.3 18.3 1.1 0.5 4.1 3.6 226.5 0.8 2.3 672.1 3.2 74.7 4.7 121.0 2.9 0.5 0.3 20.5 21.2 0.1 8.0 0.8 3.1 0.1 0.9 8.6 3.8 0.8 0.9 5.5 0.4 2.3 95.1 3.7 2.8 1.3 0.2 0.2 0.4 38.3 6.3 152.1 0.8 1.1 3.0 0.2 53.1 1.0 5.4 0.0 0.0 0.6 0.3 0.0 0.5 0.0 0.2 0.7 0.0 0.0 0.6 0.6 0.5 0.8 0.0 0.0 0.3 0.1 15.8 15.9 15.9 23.3 15.4 19.6 23.4 19.9 18.4 18.1 18.1 18.0 45.4 22.4 90.5 3.6 7.1 54.7 58.8 76.6 33.6 0.3 5.9 30.9 20.8 183.0 22.9 18.4 2.1 4.1 1.8 0.7 3.9 280.8 4.6 13.3 442.3 45.4 0.0 40.6 0.9 44.5 3.7 684.4 16.3 11.6 10.1 24.9 114.9 1444.2 11.2 0.0 0.3 0.7 0.0 40.9 66.9 29.2 1142.6 7.0 53.4 13.1 1.6 16.0 0.0 2.5 0.1 51.1 1.3 388.1 6.2 17.7 0.3 6.1 5.3 1.4 170.9 87.5 140.4 6.8 6.7 5.6 40.1 5.2 11.5 15.2 0.7 11.2 C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 2915.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 687.0;Hepatocytes: 2795.1;Leydig cells: 1193.2;Peritubular cells: 640.1" "Cancer enhanced" "Detected in all" "liver cancer: 276.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.2" "Cell line enhanced" "Detected in many" "ASC diff: 769.5;ASC TERT1: 1012.7;BJ hTERT+: 336.1;HSkMC: 540.2" "Not detected" "Not detected" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 93000000000 14000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favorable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" 416.4 136.1 26.4 207.7 28.5 1.7 252.5 27.1 43.1 309.2 36.7 192.4 84.6 209.0 147.2 152.9 315.4 543.8 191.5 25.4 34.8 60.2 2915.2 224.9 209.2 44.3 31.7 485.9 62.1 21.8 33.1 52.9 31.2 174.4 215.2 9.7 96.9 139.1 57.0 104.1 154.2 251.8 30.9 168.5 150.1 90.0 30.9 88.1 139.0 154.7 192.5 455.7 189.8 31.3 0.2 18.6 1.2 10.2 769.5 1012.7 4.5 143.3 336.1 74.7 135.7 0.9 2.0 0.5 19.7 179.6 20.2 1.1 0.3 2.1 6.7 0.7 0.7 0.5 5.6 48.2 230.3 1.8 0.9 540.2 2.8 60.2 4.4 94.2 0.1 0.2 0.4 0.1 9.9 0.0 0.4 1.6 10.3 0.0 0.6 0.2 1.1 1.5 3.1 2.5 0.8 0.9 86.6 1.8 2.1 17.4 0.1 0.0 0.5 34.2 2.6 133.8 0.2 0.6 0.5 0.8 73.6 1.2 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 26.4 28.5 27.1 43.1 25.4 34.8 44.3 31.7 31.2 30.9 30.9 31.3 37.6 16.0 41.0 9.4 5.7 76.2 18.9 22.2 23.9 0.9 4.5 15.4 21.5 171.6 15.5 3.7 0.0 3.7 0.7 0.1 1.9 285.2 6.6 8.7 272.4 30.6 0.0 112.2 2.9 42.9 2.5 687.0 11.2 7.3 5.1 25.7 93.5 2795.1 8.1 5.0 1.7 0.0 2.0 62.8 103.7 29.9 1193.2 6.4 88.9 19.7 1.0 15.2 0.0 1.5 0.6 31.7 0.1 640.1 1.8 9.7 0.0 7.1 4.6 1.1 138.1 34.9 127.6 6.3 5.3 6.3 53.8 2.6 12.8 30.7 0.2 5.2 C2CD3 DKFZP586P0123 ENSG00000168014 "C2 domain containing 3 centriole elongation regulator" Q4AC94 11 74012718-74171210 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;Alveolar cells type 2: 114.6;Excitatory neurons: 57.4;Respiratory ciliated cells: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 17.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 60.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038552, HPA038553, HPA040433" Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Centrosome" "HPA038552: AB_10669542, HPA038553: AB_2676080, HPA040433: AB_2676981" "unprognostic (3.94e-1)" "unprognostic (7.89e-2)" "unprognostic (3.68e-2)" "unprognostic (8.86e-3)" "unprognostic (1.31e-1)" "unprognostic (1.18e-1)" "unprognostic (8.48e-5)" "unprognostic (1.99e-1)" "unprognostic (4.96e-3)" "unprognostic (2.20e-1)" "unprognostic (1.74e-1)" "unprognostic (5.86e-2)" "unprognostic (2.21e-1)" "unprognostic (1.91e-1)" "unprognostic (3.11e-1)" "unprognostic (1.18e-1)" "unprognostic (2.92e-1)" 3.9 4.7 15.4 5.1 14.8 9.9 3.7 21.7 22.9 4.2 16.7 4.0 3.9 4.8 4.5 3.9 7.8 3.7 2.9 18.5 14.4 4.9 5.8 4.2 5.0 16.9 13.8 4.7 2.2 6.2 3.7 5.9 15.3 4.3 5.2 8.2 4.3 3.5 3.5 6.0 4.2 4.2 11.2 5.9 4.3 11.0 15.8 7.7 7.0 3.4 5.4 3.9 2.7 19.4 9.3 14.3 11.7 14.3 5.2 4.8 5.6 13.7 8.8 16.0 13.0 24.4 7.4 9.0 9.2 5.2 15.5 13.9 14.7 3.8 19.3 12.4 7.0 12.4 21.3 10.8 8.8 12.0 16.9 4.8 4.8 13.4 9.7 5.1 9.0 11.1 14.2 15.7 13.3 7.7 14.1 8.3 9.4 17.8 7.7 14.3 60.4 9.0 4.6 13.0 15.6 9.2 22.4 8.4 21.2 11.9 16.5 7.8 12.7 10.3 17.0 10.1 11.0 11.7 8.5 26.1 4.0 6.0 11.1 17.8 2.0 3.0 2.2 2.3 2.0 2.3 1.4 1.8 1.3 4.4 2.1 2.1 12.6 2.9 4.7 2.0 1.0 0.7 15.4 14.8 21.7 22.9 18.5 14.4 16.9 13.8 15.3 11.2 15.8 19.4 6.5 70.5 114.6 28.1 10.5 5.2 3.6 4.8 9.6 8.7 6.2 5.8 5.1 4.3 36.0 9.2 4.2 3.8 5.6 7.6 0.0 4.0 33.0 18.4 9.4 9.8 7.7 12.2 57.4 2.6 2.9 9.6 15.3 8.9 36.6 8.5 5.0 3.0 5.0 11.8 52.1 5.0 4.1 7.6 6.6 24.7 4.4 12.7 7.2 26.2 4.9 4.8 10.3 37.7 38.5 3.8 2.8 6.4 9.5 3.4 3.4 1.8 57.1 14.8 6.6 7.2 5.2 11.1 6.9 6.4 4.5 2.3 14.0 5.4 5.4 4.7 CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463968-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 687.4;stomach 1: 1108.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1773.2;Erythroid cells: 2448.1;Gastric mucus-secreting cells: 1380.7;Muller glia cells: 1536.4;Paneth cells: 781.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 263.8;HEK 293: 1097.8;THP-1: 461.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001550, CAB010102" Enhanced NA Yes 570000000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "CAB010102: AB_626796, HPA001550: AB_1078393" "unprognostic (6.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (5.23e-2)" "unprognostic (1.57e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.57e-6)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" 7.4 10.1 95.9 36.8 127.5 246.8 37.9 122.1 143.8 5.0 444.0 687.4 285.2 2.9 10.6 19.8 2.7 112.7 15.9 105.2 107.8 331.2 273.5 43.1 6.6 115.5 112.0 0.4 55.1 10.1 6.1 19.6 114.2 1.9 643.6 390.4 74.7 68.4 42.7 81.0 31.3 32.3 98.2 8.4 1108.7 21.2 115.6 5.1 15.9 62.8 4.3 2.9 5.2 145.5 3.7 2.8 12.2 0.0 0.1 0.0 31.2 0.0 0.0 0.0 0.0 15.1 0.9 0.0 9.5 0.0 0.1 263.8 37.4 13.2 0.0 0.0 1097.8 35.8 17.0 0.5 0.0 23.7 5.1 0.0 63.9 0.0 3.7 0.0 0.0 0.0 0.3 0.2 0.0 0.4 0.4 41.4 3.7 86.5 0.0 21.2 1.3 0.5 3.7 8.8 0.2 0.3 5.0 0.0 0.1 9.6 0.0 461.5 0.0 0.0 6.6 0.0 0.4 0.4 1.0 0.1 1.8 0.1 0.0 51.2 5.3 8.6 0.2 15.0 7.4 1.3 0.1 0.8 15.4 3.0 0.0 0.0 12.6 0.1 13.4 1.4 0.0 33.3 95.9 127.5 122.1 143.8 105.2 107.8 115.5 112.0 114.2 98.2 115.6 145.5 19.4 16.0 79.9 34.0 19.6 90.6 1.3 152.5 17.6 23.1 56.9 18.4 19.8 430.4 22.4 161.8 64.6 15.2 2.4 1773.2 348.3 60.1 65.9 3.3 1.3 26.7 30.5 2448.1 1.4 11.3 403.1 6.4 1380.7 8.3 15.9 0.4 4.2 135.6 35.4 13.5 22.3 116.0 10.2 11.0 216.5 232.1 3.4 51.8 74.7 6.5 6.6 1536.4 1.0 3.0 226.4 16.1 781.9 2.2 10.3 3.5 0.3 468.2 3.9 66.1 0.0 12.1 8.2 3.1 2.8 31.2 111.7 17.1 11.7 0.7 390.8 0.5 CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187341964-187448460 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 70.7;lung: 76.8" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Endometrial stromal cells: 92.7;Endothelial cells: 248.7;Hepatic stellate cells: 259.2;Oligodendrocyte precursor cells: 293.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.6;myeloid DC: 9.2;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 9.2;monocytes: 2.6" "Cell line enriched" "Detected in some" 4 "HUVEC TERT2: 173.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA008070: AB_1845912, HPA046515: AB_2679681" "unprognostic (7.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-3)" "unprognostic (7.60e-3)" "unprognostic (9.25e-3)" "unprognostic (4.14e-2)" "unprognostic (7.71e-3)" "unprognostic (3.32e-1)" "unprognostic (3.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" 70.7 6.3 3.4 12.3 4.0 0.4 15.8 6.1 4.4 27.8 3.4 6.9 6.0 21.5 4.6 8.6 11.4 24.4 20.4 3.9 3.8 14.0 12.6 76.8 7.9 11.1 6.2 15.7 4.3 13.0 3.6 11.7 10.8 7.3 9.5 0.9 7.1 7.7 6.2 3.9 6.3 27.1 15.5 8.6 7.1 2.7 3.9 4.6 28.3 20.2 9.1 14.1 4.7 15.2 0.2 0.0 8.8 0.0 6.2 1.6 0.0 0.8 1.3 0.1 1.0 0.0 1.0 0.0 2.3 0.7 0.2 0.0 0.0 0.6 0.2 1.5 0.5 1.5 0.0 0.2 4.9 0.2 0.0 4.6 0.2 0.3 2.1 0.5 173.6 0.1 0.0 2.5 1.2 0.0 0.8 0.1 0.5 0.0 0.0 0.0 3.1 0.5 40.5 0.0 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.2 25.3 0.7 0.1 0.1 0.4 6.2 0.1 0.7 0.4 0.0 0.0 0.0 2.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 9.2 0.0 0.8 0.1 0.1 1.0 1.0 2.6 0.0 0.9 3.4 4.0 6.1 4.4 3.9 3.8 11.1 6.2 10.8 15.5 3.9 15.2 138.3 0.0 11.9 19.6 1.2 9.3 2.3 1.7 21.6 0.2 0.8 1.8 12.3 2.8 3.6 0.0 0.0 0.4 2.4 0.0 3.9 0.3 0.8 3.1 92.7 248.7 0.0 4.8 15.4 0.4 0.2 56.5 1.1 1.7 5.1 12.3 259.2 1.8 0.9 0.0 2.1 0.0 2.0 10.3 29.7 1.0 7.8 15.4 10.6 47.8 16.1 0.0 1.0 293.0 1.0 0.1 0.0 2.6 4.9 1.9 0.0 13.2 2.8 0.1 6.6 4.1 21.5 1.3 0.7 18.2 6.8 0.3 3.0 6.0 0.0 1.8 CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991716-79009867 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 139.5;Intestinal goblet cells: 155.6;Syncytiotrophoblasts: 101.5;Undifferentiated cells: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 445.4;T-47d: 282.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced Supported "Golgi apparatus" NA Yes 3300000 "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971" "unprognostic (1.98e-2)" "unprognostic (2.49e-2)" "unprognostic (1.50e-2)" "unprognostic (5.36e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.41e-4)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.21e-4)" "unprognostic (7.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" 15.8 23.9 10.4 24.7 12.4 19.1 25.4 13.6 11.3 32.3 13.8 89.2 51.9 17.4 8.7 44.8 18.2 25.2 17.0 11.1 12.6 16.1 17.3 16.4 15.2 14.6 14.5 14.6 19.6 24.5 17.5 25.9 13.9 71.8 82.8 7.4 62.7 32.4 14.9 14.9 55.5 15.5 13.8 26.5 51.1 20.7 14.5 14.7 13.9 12.4 15.1 16.7 21.7 17.8 106.5 112.1 31.9 46.3 29.7 35.2 38.9 66.0 51.3 66.7 55.9 53.8 99.6 25.3 36.1 46.1 83.0 53.7 27.1 49.8 68.4 43.0 46.4 33.7 34.1 45.9 25.0 33.0 51.6 33.7 32.4 62.7 34.2 40.9 116.1 42.5 42.3 43.2 46.4 58.4 50.2 19.8 22.1 445.4 103.1 27.6 51.8 29.8 29.8 53.5 45.6 45.4 33.9 227.2 50.2 50.3 282.6 38.6 56.6 101.9 90.5 46.4 83.1 48.9 43.8 24.3 64.4 24.9 65.3 6.3 4.0 8.7 5.5 4.4 5.7 3.9 4.3 4.8 3.8 2.5 4.1 4.1 17.4 3.1 3.0 2.7 3.6 4.6 10.4 12.4 13.6 11.3 11.1 12.6 14.6 14.5 13.9 13.8 14.5 17.8 12.6 28.9 20.6 5.9 11.8 16.6 15.3 16.8 6.8 6.4 49.9 16.3 13.3 14.3 15.1 12.9 14.6 36.6 8.9 139.5 3.9 34.7 14.0 10.7 13.1 16.3 51.0 15.2 4.1 28.8 39.4 13.5 38.2 19.0 5.7 20.0 41.7 14.4 24.9 5.0 5.2 155.6 16.2 12.4 9.5 15.7 11.8 14.2 14.2 3.7 18.1 8.1 11.3 5.0 10.2 37.7 55.8 7.5 16.6 33.4 39.4 6.7 9.7 8.7 6.6 9.5 13.3 23.9 5.8 12.0 13.1 101.5 11.1 11.3 100.2 19.4 CARS1 CARS ENSG00000110619 "Cysteinyl-tRNA synthetase 1" P49589 11 3000922-3057613 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 10.3;Cardiomyocytes: 8.8;Cytotrophoblasts: 22.2;Extravillous trophoblasts: 40.7;Hofbauer cells: 22.0;Syncytiotrophoblasts: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737" Enhanced Enhanced Cytosol NA NA 200000 "Cluster 14: Monocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB075734: AB_2665740, CAB075735: AB_2665741, CAB075736: AB_2665742, CAB075737: AB_2665743, HPA002383: AB_1078399, HPA002384: AB_1846033" "unprognostic (9.10e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-3)" "unprognostic (1.43e-1)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (8.00e-2)" "unprognostic (5.51e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "unprognostic (3.46e-1)" 22.1 17.4 8.1 12.0 8.5 7.3 19.9 8.7 21.6 13.6 8.4 21.8 12.0 15.9 7.5 19.2 12.8 10.3 13.3 8.2 9.8 13.7 21.1 17.5 12.7 9.6 9.9 8.9 32.8 9.6 18.6 10.3 10.6 12.7 12.8 5.3 20.6 6.8 31.7 23.8 17.4 16.0 9.7 17.2 23.5 16.8 9.9 14.6 17.3 14.7 17.8 18.1 14.9 11.5 29.2 14.0 17.8 55.6 67.3 61.4 16.2 70.0 78.6 46.7 84.1 34.2 64.7 43.1 20.1 88.2 0.0 68.7 58.3 78.6 64.0 123.7 13.5 24.4 23.7 25.8 161.1 50.9 50.2 102.2 64.1 40.1 46.8 0.0 62.3 103.6 42.2 147.0 47.1 41.9 35.7 0.0 65.2 97.9 25.0 17.2 29.7 54.9 0.0 46.1 39.0 49.7 17.1 48.1 80.1 13.3 0.0 0.1 21.8 19.5 18.2 48.2 0.2 107.8 106.8 27.2 0.1 26.6 40.3 16.3 18.6 13.5 20.9 15.4 17.4 10.9 18.3 18.6 19.4 8.5 9.9 16.0 25.4 23.7 37.9 7.5 27.0 19.2 8.1 8.5 8.7 21.6 8.2 9.8 9.6 9.9 10.6 9.7 9.9 11.5 10.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 22.2 8.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 40.7 3.7 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 32.3 1.4 0.0 0.0 0.0 CASK "CAGH39, FGS4, LIN2, TNRC8" ENSG00000147044 "Calcium/calmodulin dependent serine protein kinase" O14936 X 41514934-41923554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 135.8;Oligodendrocyte precursor cells: 447.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 47.1" "Lineage enriched" "Detected in many" 10 "granulocytes: 47.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001949, HPA023857" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "CAB001949: , HPA023857: AB_1846035" "unprognostic (6.30e-2)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (2.48e-3)" "unprognostic (1.56e-1)" "unprognostic (1.29e-1)" "unprognostic (1.42e-3)" "unprognostic (3.58e-1)" "unprognostic (1.02e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (6.11e-5)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.72e-2)" "unprognostic (1.15e-2)" "unprognostic (2.13e-2)" "unprognostic (2.85e-2)" 10.2 11.1 13.6 11.9 12.9 7.3 15.7 12.3 11.1 11.6 12.4 25.3 32.1 11.1 9.4 13.7 10.5 18.5 6.8 14.2 17.1 16.4 13.4 12.2 12.5 13.2 19.4 13.5 12.8 11.8 6.3 16.3 15.7 10.6 27.3 19.8 13.2 8.3 5.0 9.3 31.9 12.0 15.4 12.4 19.8 3.6 25.2 15.4 10.6 6.1 10.4 15.3 8.8 18.0 27.4 32.5 31.4 19.1 21.6 18.6 10.9 23.2 18.7 13.2 12.3 72.3 42.6 0.4 12.0 29.3 23.8 52.3 35.2 23.2 22.8 25.4 20.9 0.6 27.7 26.2 22.1 4.4 3.6 19.8 63.2 25.1 30.1 27.5 11.6 15.3 2.2 21.3 30.2 30.9 8.4 2.2 29.7 37.6 22.6 12.7 79.8 13.2 31.2 54.8 29.7 15.6 43.7 17.7 13.9 52.7 19.0 0.8 14.2 24.4 25.8 22.1 13.3 7.6 5.2 9.5 24.4 3.1 16.9 47.1 1.5 8.7 0.8 1.1 0.8 0.7 0.9 1.3 0.4 0.9 1.2 1.1 1.7 4.3 0.7 0.5 4.5 0.6 13.6 12.9 12.3 11.1 14.2 17.1 13.2 19.4 15.7 15.4 25.2 18.0 13.0 12.8 20.4 101.9 8.8 32.6 42.7 11.1 8.0 42.2 23.7 16.5 7.8 8.6 14.6 7.3 22.9 2.0 12.1 25.8 50.9 13.7 0.9 9.6 24.1 16.0 13.8 0.8 96.6 14.5 0.7 18.8 18.8 11.9 0.0 17.4 8.9 15.0 21.3 50.5 135.8 28.7 14.2 2.8 21.5 1.0 9.9 10.7 10.6 60.0 2.5 9.3 0.0 447.8 59.7 22.1 24.1 9.4 7.0 16.4 35.2 20.9 15.7 25.7 19.7 38.2 20.6 2.9 2.1 13.9 32.5 1.6 26.5 47.7 41.8 33.2 CASP14 "MGC119078, MGC119079, MICE" ENSG00000105141 "Caspase 14" P31944 19 15049480-15058293 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Hydrolase, Protease, Thiol protease" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "skin 1: 486.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 96.0" "Cancer enhanced" "Detected in many" "cervical cancer: 62.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "hTCEpi: 49.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010059, HPA027062" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 3600000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" Mitochondria "CAB010059: AB_626800, HPA027062: AB_2672101" "unprognostic (1.17e-2)" "unprognostic (6.44e-3)" "unprognostic (6.22e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (9.42e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (5.96e-4)" "unprognostic (2.68e-1)" "unprognostic (4.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.97e-1)" 0.6 0.0 0.1 0.0 0.4 0.4 7.8 0.4 0.2 3.9 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.0 0.6 0.1 0.0 0.0 0.3 0.8 0.0 0.1 1.1 4.2 1.4 486.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.0 0.0 0.0 0.0 0.0 19.9 1.0 1.1 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.4 0.2 0.2 0.1 0.3 0.1 0.3 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 19.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 2.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 96.0 0.7 0.1 0.0 0.0 0.8 CAST ENSG00000153113 Calpastatin P20810 5 96525267-96779595 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 858.4;Early spermatids: 979.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009491, HPA036881, HPA036882, HPA075906" Enhanced Enhanced "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 17000000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum, Cytosol" "Plasma membrane" "CAB009491: AB_2259755, HPA036881: AB_2675359, HPA036882: AB_2675360, HPA075906: " "unprognostic (2.17e-1)" "unprognostic (1.39e-1)" "unprognostic (2.44e-2)" "unprognostic (1.91e-2)" "unprognostic (4.68e-2)" "unprognostic (1.45e-1)" "unprognostic (3.79e-1)" "unprognostic (4.53e-3)" "unprognostic (1.94e-2)" "unprognostic (6.11e-3)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.66e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.16e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (4.98e-4)" 144.4 68.4 32.3 86.1 36.3 119.1 104.1 35.0 40.8 147.2 55.5 160.1 120.5 83.8 49.0 342.8 79.7 78.7 303.7 30.7 42.2 82.0 116.8 112.1 52.9 46.7 43.2 83.1 56.1 111.7 51.2 116.1 44.4 100.2 148.2 17.1 130.0 78.7 317.3 157.4 137.2 92.2 38.3 64.1 100.5 98.8 39.1 43.1 97.9 166.4 104.3 129.4 216.4 41.7 300.3 239.7 42.6 112.1 240.1 390.1 145.4 220.9 288.8 169.1 215.8 60.4 189.6 44.1 189.8 286.1 263.1 465.6 81.3 283.5 202.8 292.4 78.5 65.9 251.0 71.1 172.9 38.9 100.1 201.8 254.8 239.6 375.0 222.9 194.8 33.5 51.7 144.5 196.4 98.0 17.9 2.0 35.4 85.0 89.9 18.2 141.9 78.3 327.1 114.1 179.6 45.0 222.6 118.2 142.5 94.0 77.4 39.5 263.9 239.0 94.6 154.9 211.4 51.2 140.4 22.1 264.7 21.8 67.5 10.5 156.6 24.1 75.6 85.3 74.1 79.4 68.2 76.9 107.5 79.1 34.8 45.7 38.2 61.6 109.8 28.8 79.2 108.1 32.3 36.3 35.0 40.8 30.7 42.2 46.7 43.2 44.4 38.3 39.1 41.7 251.6 403.8 221.4 58.1 153.8 239.6 439.8 223.6 169.0 39.4 133.6 84.5 858.4 163.0 277.0 108.5 18.8 181.2 227.1 484.0 133.1 263.6 979.7 348.0 213.4 188.5 142.1 229.3 60.2 249.7 96.2 259.0 153.4 327.8 177.1 71.8 138.8 169.3 113.7 13.5 53.0 253.9 103.7 209.4 259.1 414.4 172.1 243.8 131.6 63.7 354.4 36.9 293.6 33.2 70.2 325.1 346.8 146.3 126.3 314.7 302.9 152.3 379.0 19.5 92.1 267.8 175.0 23.6 17.9 348.9 251.7 140.8 207.7 69.8 221.2 548.5 CATSPER2 ENSG00000166762 "Cation channel sperm associated 2" Q96P56 15 43628503-43668118 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Differentiation, Ion transport, Spermatogenesis, Transport" "Calcium channel, Developmental protein, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.6;retina: 22.8;testis: 15.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 254.4;Early spermatids: 73.6;Rod photoreceptor cells: 221.8;Spermatocytes: 117.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 14.6" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (6.88e-3)" "unprognostic (6.79e-2)" "unprognostic (2.08e-2)" "unprognostic (2.65e-2)" "unprognostic (4.05e-1)" "unprognostic (1.05e-2)" "unprognostic (7.11e-3)" "unprognostic (1.48e-2)" "unprognostic (6.35e-2)" "unprognostic (1.15e-2)" "unprognostic (1.09e-2)" "unprognostic (3.37e-2)" "unprognostic (3.74e-3)" "unprognostic (1.15e-1)" "unprognostic (6.04e-2)" "unprognostic (8.87e-2)" "unprognostic (8.23e-5)" 1.2 1.4 2.0 0.8 2.2 4.2 1.8 14.6 4.0 1.3 0.1 2.3 3.3 1.4 5.4 2.4 1.4 0.7 0.9 2.2 0.7 1.4 1.5 1.2 2.0 1.4 0.6 1.6 1.2 4.0 3.2 0.8 1.7 1.6 2.3 22.8 1.6 2.2 1.2 5.4 3.8 0.6 0.1 1.5 1.8 15.5 0.9 0.9 1.9 1.5 1.5 1.7 1.3 3.1 2.0 2.8 1.2 4.4 0.0 0.0 2.0 0.7 1.7 1.2 2.9 0.7 1.1 2.4 1.0 0.5 1.4 4.4 1.1 3.9 1.2 2.0 5.4 7.0 11.2 1.0 1.8 1.6 2.2 0.2 3.0 1.7 4.3 3.2 1.5 4.3 2.8 2.4 0.4 0.5 1.3 2.8 0.4 2.7 1.2 1.9 1.4 1.1 2.4 3.2 2.6 0.9 1.1 1.6 0.1 1.6 3.2 1.5 0.4 3.0 1.3 0.0 1.8 0.4 0.3 5.1 2.1 4.9 1.1 0.1 0.3 0.1 0.3 0.1 0.4 1.1 0.2 0.4 0.2 0.3 0.3 0.7 0.5 0.5 0.3 0.4 0.1 0.0 2.0 2.2 14.6 4.0 2.2 0.7 1.4 0.6 1.7 0.1 0.9 3.1 4.8 0.0 4.5 0.0 4.9 7.0 8.2 8.3 1.8 56.7 6.9 6.9 4.2 5.7 8.0 7.3 254.4 6.0 6.0 3.9 3.9 3.2 73.6 5.2 2.5 6.0 21.5 2.7 0.0 2.7 2.1 3.2 6.1 4.2 9.5 29.7 8.6 3.9 4.3 38.7 0.0 4.6 4.1 5.0 6.5 37.4 6.2 4.5 1.8 0.0 4.5 13.4 7.2 0.0 0.0 2.0 3.3 7.2 1.1 6.7 11.1 4.1 10.8 221.8 0.0 9.3 5.1 117.4 17.1 2.7 8.0 3.0 4.6 5.8 8.5 8.4 CBL "c-Cbl, CBL2, RNF55" ENSG00000110395 "Cbl proto-oncogene" P22681 11 119206298-119313926 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004350, HPA027956" Enhanced Approved Cytosol NA NA 67000 "Cluster 1: Neutrophils - Mixed function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB004350: AB_2244054, HPA027956: AB_10601094" "unprognostic (2.52e-1)" "unprognostic (1.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-2)" "unprognostic (2.92e-1)" "unprognostic (4.10e-3)" "unprognostic (9.75e-2)" "unprognostic (1.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.03e-2)" "unprognostic (5.23e-2)" "unprognostic (5.21e-2)" "unprognostic (5.27e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" 6.8 4.0 5.6 9.5 5.7 8.5 5.6 5.3 6.5 5.0 0.2 6.2 3.9 6.5 3.4 5.6 5.6 3.9 4.1 5.3 8.1 4.4 2.7 7.9 10.7 5.8 6.3 3.7 3.8 6.1 2.9 6.4 6.5 4.0 5.0 8.3 3.6 4.6 2.5 5.2 6.6 7.4 5.2 9.9 5.2 18.2 7.9 22.5 4.1 3.2 11.2 5.8 4.9 6.0 10.7 7.6 26.6 16.7 7.8 9.2 16.0 11.2 11.4 10.8 10.2 16.7 12.6 25.1 10.0 14.0 21.7 15.2 18.4 9.4 22.7 14.8 4.7 26.4 6.2 5.1 9.5 30.3 27.9 8.1 10.1 26.7 28.4 11.1 26.3 23.7 21.7 9.9 19.1 11.3 16.2 17.0 14.0 9.2 8.8 17.5 13.5 4.6 9.3 8.2 3.7 11.3 20.9 8.8 7.3 18.1 9.4 24.8 22.8 16.0 11.5 11.6 14.7 3.3 5.3 19.9 6.7 25.4 11.9 0.8 2.4 2.0 0.9 2.8 0.8 1.5 1.1 0.9 2.6 1.2 1.2 1.3 8.6 0.4 2.5 1.4 1.0 0.9 5.6 5.7 5.3 6.5 5.3 8.1 5.8 6.3 6.5 5.2 7.9 6.0 23.2 9.6 8.3 23.5 23.2 18.0 5.9 7.5 19.4 14.0 13.6 11.7 8.8 5.7 6.0 11.0 45.9 6.3 24.0 7.6 1.9 6.1 28.2 9.9 19.6 23.2 8.4 5.7 38.5 6.7 10.5 9.4 9.2 16.8 3.8 20.8 20.0 3.1 16.0 13.5 39.1 4.9 2.0 59.1 43.2 42.0 7.8 41.2 16.0 45.0 46.8 13.2 22.6 26.2 19.6 10.6 11.6 12.8 19.7 8.0 5.1 5.4 4.8 33.3 26.3 11.6 22.7 38.0 36.2 18.5 21.9 7.0 24.9 10.6 5.1 10.9 CC2D2A "JBTS9, KIAA1345, MKS6" ENSG00000048342 "Coiled-coil and C2 domain containing 2A" Q9P2K1 4 15469865-15601552 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 84.7" "Cell type enriched" "Detected in many" 4 "Cone photoreceptor cells: 569.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044124 Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA044124: AB_10969197" "unprognostic (1.88e-1)" "unprognostic (2.05e-3)" "unprognostic (6.01e-3)" "unprognostic (4.23e-3)" "unprognostic (2.13e-2)" "unprognostic (1.10e-1)" "unprognostic (8.63e-2)" "unprognostic (4.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.57e-2)" "unprognostic (2.23e-2)" "unprognostic (7.33e-2)" "prognostic favorable (3.42e-9)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (2.18e-2)" 8.3 9.3 13.5 2.7 13.0 2.7 8.8 14.2 16.5 14.2 22.1 17.3 4.9 12.8 11.1 8.3 34.2 12.4 7.4 13.2 13.5 23.6 2.9 10.7 2.0 13.7 14.6 11.7 5.1 10.0 12.7 8.5 12.6 10.0 5.9 84.7 3.3 12.5 2.5 2.3 5.0 15.4 12.0 3.3 8.2 4.9 14.7 1.2 8.2 11.1 1.4 9.3 6.4 12.7 5.4 11.3 15.6 7.0 18.4 34.4 3.8 6.8 11.5 12.7 15.5 5.1 13.2 0.5 7.3 13.1 27.7 3.4 13.1 8.7 15.9 0.0 7.3 5.5 10.1 7.1 13.5 0.5 0.1 25.0 22.8 20.7 15.5 23.3 5.9 0.2 14.7 0.4 24.4 3.9 0.2 0.9 25.9 0.2 23.3 3.5 4.9 1.1 32.1 2.6 9.7 11.1 4.3 3.1 32.2 14.6 4.9 1.3 2.2 20.2 12.0 8.6 14.4 0.4 0.5 0.3 24.3 0.3 13.1 1.9 2.4 0.2 0.4 1.6 0.6 0.3 0.3 0.1 3.8 0.3 0.2 0.4 4.8 0.9 0.8 0.2 0.9 0.6 13.5 13.0 14.2 16.5 13.2 13.5 13.7 14.6 12.6 12.0 14.7 12.7 8.4 12.8 14.6 39.8 0.7 2.2 5.6 5.7 14.2 15.1 6.5 9.0 22.9 10.0 23.5 25.8 569.2 10.2 0.3 0.8 33.2 6.6 12.0 96.8 14.0 7.0 6.0 2.7 20.9 0.9 3.1 18.7 4.1 9.0 0.0 15.2 8.9 1.6 5.0 8.4 43.4 0.9 8.2 5.7 4.6 6.7 9.3 4.4 12.4 16.9 1.2 18.4 0.0 62.8 19.5 1.0 0.5 16.6 1.3 4.4 2.1 57.1 128.4 136.4 6.6 14.7 17.7 2.6 0.7 6.4 1.3 1.5 1.9 12.9 2.9 4.0 CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 33.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.1;Rod photoreceptor cells: 38.2;Theca cells: 78.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "basophil: 9.2" "Lineage enriched" "Detected in single" 19 "granulocytes: 9.2" "Cell line enhanced" "Detected in many" "BJ: 101.2;BJ hTERT+: 103.2;BJ hTERT+ SV40 Large T+ RasG12V: 96.4;HBF TERT88: 113.3;hTERT-HME1: 153.2;LHCN-M2: 176.9;TIME: 93.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in many" "HPA041361, HPA041374" Uncertain Supported "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" 4.1 10.2 2.7 1.2 3.4 0.5 1.8 2.2 3.0 10.5 0.7 16.7 1.1 6.9 0.5 2.8 8.3 1.3 2.1 6.5 1.1 3.3 5.7 9.9 1.3 0.2 1.9 33.5 1.1 2.9 0.4 0.5 0.3 2.4 2.8 1.1 0.6 4.0 15.3 3.0 2.5 3.2 0.2 0.5 1.6 0.6 3.7 1.2 0.9 0.9 0.7 0.8 1.3 1.5 20.6 1.9 0.0 0.2 15.1 47.2 30.7 101.2 103.2 73.5 96.4 0.3 0.3 0.4 0.2 40.6 16.7 2.3 0.2 65.5 113.3 0.4 0.3 0.2 0.4 0.3 35.1 0.3 0.2 32.0 2.9 57.0 153.2 31.2 3.6 0.3 0.2 0.5 176.9 0.6 0.1 0.2 0.3 0.0 0.6 0.1 0.2 0.2 3.9 2.0 0.4 0.7 0.3 0.2 0.9 7.2 0.3 0.5 93.3 0.2 10.0 15.3 0.3 0.3 0.3 0.2 5.0 0.3 2.4 9.2 0.2 0.5 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.5 0.4 0.1 0.2 0.1 0.1 2.7 3.4 2.2 3.0 6.5 1.1 0.2 1.9 0.3 0.2 3.7 1.5 1.5 3.2 1.3 3.9 0.2 4.6 2.0 1.0 2.2 6.4 0.8 0.4 1.6 2.8 1.9 0.0 8.4 1.0 0.2 0.2 0.0 0.2 0.8 8.8 5.1 2.2 0.0 0.0 56.1 0.2 1.3 14.5 0.0 0.6 1.3 6.8 9.7 0.2 0.4 15.2 15.1 0.0 0.0 1.0 8.9 1.1 9.6 0.5 7.2 1.0 0.2 2.4 0.0 0.5 0.7 0.3 0.0 0.4 0.1 1.5 0.1 0.1 0.9 38.2 0.0 1.6 5.9 0.4 0.9 0.2 4.3 0.8 1.2 78.0 0.1 0.9 CCDC174 "C3orf19, FLJ33839" ENSG00000154781 "Coiled-coil domain containing 174" Q6PII3 3 14651746-14672659 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 152.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043468, HPA060129" Approved Enhanced Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA043468: AB_2678493, HPA060129: AB_2684208" "unprognostic (6.10e-2)" "unprognostic (7.96e-2)" "unprognostic (2.92e-1)" "unprognostic (3.26e-2)" "unprognostic (6.58e-3)" "unprognostic (5.06e-2)" "unprognostic (6.48e-3)" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (5.29e-2)" "unprognostic (3.86e-2)" "prognostic unfavorable (4.75e-4)" "unprognostic (1.15e-2)" "unprognostic (2.30e-3)" "unprognostic (2.04e-1)" "unprognostic (2.64e-1)" "prognostic favorable (3.81e-5)" 9.5 7.0 7.7 7.0 8.5 17.2 9.2 8.8 8.5 10.9 6.8 9.8 9.4 10.4 7.5 8.9 9.4 6.8 8.2 7.7 8.0 8.9 8.7 7.1 9.6 8.1 8.4 14.7 10.1 11.9 8.6 8.6 8.1 9.7 7.3 6.7 8.6 8.0 11.1 9.7 9.5 7.9 7.5 10.6 10.3 9.1 8.2 11.6 9.0 10.7 10.2 9.6 9.5 9.6 6.2 6.7 10.0 10.7 13.6 11.1 25.3 8.1 11.6 10.0 7.8 7.5 7.0 12.8 5.8 7.2 6.8 5.3 7.3 6.8 7.8 9.7 8.9 13.0 8.1 8.1 19.7 12.9 14.5 12.9 17.0 13.5 16.5 14.0 8.6 13.4 13.2 11.4 7.6 10.9 13.6 11.3 13.5 10.1 10.9 10.1 9.3 10.6 10.4 10.8 4.8 13.1 9.5 7.4 13.4 11.6 11.2 18.1 8.0 8.0 7.8 7.4 9.5 15.0 14.3 14.7 8.0 9.8 11.1 25.4 10.7 22.2 12.9 11.3 15.2 17.4 16.1 15.1 9.7 16.4 17.4 13.8 20.5 18.8 12.2 10.9 12.5 10.0 7.7 8.5 8.8 8.5 7.7 8.0 8.1 8.4 8.1 7.5 8.2 9.6 29.5 9.6 34.5 11.4 48.0 16.2 31.3 38.0 26.7 32.8 25.0 28.4 37.0 32.9 35.7 12.9 20.9 32.1 42.3 27.3 56.7 34.7 152.5 27.3 35.4 31.0 18.5 43.4 12.8 34.9 25.2 33.7 20.4 34.7 52.0 22.0 38.6 29.3 26.5 15.2 16.6 34.1 32.6 27.2 16.5 59.1 33.5 30.5 14.2 5.6 45.2 22.2 34.0 11.1 15.8 38.2 34.9 40.3 34.9 28.8 36.8 46.4 31.1 24.9 32.9 28.4 37.2 78.7 33.5 19.9 13.5 65.7 41.6 23.5 23.1 31.8 CCDC22 "CXorf37, JM1" ENSG00000101997 "Coiled-coil domain containing 22" O60826 X 49235470-49250520 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport, Ubl conjugation pathway" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000229, HPA000888, HPA075980" Uncertain Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Vesicles" "HPA000229: , HPA000888: AB_1078420, HPA075980: " "unprognostic (1.24e-2)" "unprognostic (1.96e-2)" "unprognostic (1.98e-2)" "unprognostic (3.45e-1)" "unprognostic (1.36e-1)" "unprognostic (2.80e-2)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.68e-2)" "unprognostic (2.62e-2)" "unprognostic (1.70e-1)" "unprognostic (4.57e-3)" "unprognostic (3.61e-2)" "unprognostic (4.99e-2)" "unprognostic (6.99e-2)" "unprognostic (2.57e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-3)" 10.3 12.3 9.4 10.1 10.0 18.6 10.3 9.9 10.8 11.7 8.8 12.1 10.4 12.2 5.3 14.2 11.3 6.4 12.8 9.4 9.2 12.3 12.9 10.7 15.0 10.8 9.4 11.2 14.2 8.7 11.2 6.9 10.1 13.5 5.2 4.7 12.3 8.7 17.2 13.8 13.4 6.0 9.6 20.5 12.9 3.8 10.0 13.6 11.0 7.7 8.5 11.9 11.1 10.8 18.8 16.0 9.6 33.5 8.8 8.9 20.4 10.9 7.9 12.0 13.6 16.3 16.0 6.9 15.9 9.7 14.3 15.0 10.6 18.0 4.9 18.1 23.6 7.3 15.6 15.5 14.7 20.8 12.4 8.2 15.2 15.9 8.6 6.1 11.9 13.7 14.7 11.8 8.6 58.3 15.3 24.4 11.2 9.5 23.2 22.0 15.6 30.1 9.4 9.4 11.4 8.8 16.7 19.4 15.0 9.8 30.2 20.2 13.3 15.4 16.5 19.2 11.6 21.2 12.6 12.5 16.8 38.5 12.3 8.6 37.0 23.8 18.3 30.9 20.1 18.9 18.8 21.3 38.2 16.8 16.7 19.6 2.8 10.8 27.1 15.1 21.8 28.0 9.4 10.0 9.9 10.8 9.4 9.2 10.8 9.4 10.1 9.6 10.0 10.8 8.6 0.0 4.4 3.3 15.0 5.6 9.6 13.0 6.2 11.6 7.4 6.1 2.4 15.7 12.0 11.0 6.2 15.2 11.2 12.5 15.6 13.9 0.3 5.8 4.6 7.8 6.7 8.6 3.7 7.3 14.8 7.6 7.1 6.9 11.4 8.6 11.0 7.2 32.0 1.7 2.9 18.2 8.2 14.4 11.9 0.4 8.1 13.8 7.2 1.9 18.0 9.9 9.2 1.0 4.2 8.6 7.6 7.5 10.2 6.2 15.6 12.1 5.6 8.0 6.6 9.1 9.5 0.1 0.9 8.0 6.7 20.2 13.3 11.0 15.7 8.3 CCDC8 "3M3, DKFZp564K0322, PPP1R20" ENSG00000169515 "Coiled-coil domain containing 8" Q9H0W5 19 46410329-46413564 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 36.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.0;Distal tubular cells: 39.2;Granulosa cells: 25.7;Leydig cells: 70.8;Peritubular cells: 57.9;Theca cells: 32.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 18.5;AN3-CA: 22.2;HSkMC: 19.6;K-562: 20.3;RH-30: 24.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041993 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA041993: AB_10795388" "unprognostic (3.05e-3)" "unprognostic (2.16e-1)" "unprognostic (2.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.39e-3)" "unprognostic (3.69e-1)" "unprognostic (6.64e-2)" "unprognostic (5.16e-2)" "unprognostic (7.77e-2)" "unprognostic (1.62e-1)" "unprognostic (1.15e-1)" "unprognostic (5.72e-2)" "prognostic favorable (1.72e-5)" "unprognostic (5.43e-3)" "unprognostic (5.77e-2)" "unprognostic (4.09e-2)" "unprognostic (4.18e-3)" 4.1 16.3 4.1 2.7 3.8 0.7 8.8 3.9 2.6 13.9 7.5 3.3 0.9 13.9 10.5 1.3 22.9 4.2 24.7 3.6 3.9 11.2 0.7 4.4 0.9 5.2 7.4 36.8 13.6 9.1 12.9 6.7 5.3 6.4 1.2 1.3 10.8 7.5 2.1 3.1 2.2 6.5 4.8 2.3 2.2 5.9 4.2 5.6 9.0 2.4 0.8 7.5 7.3 4.4 1.9 0.1 18.5 22.2 4.8 6.0 8.9 9.6 0.0 2.1 0.9 0.1 0.1 0.2 12.5 7.6 0.4 0.2 0.1 15.0 1.0 0.0 9.4 0.0 0.2 1.0 16.0 0.1 0.1 19.6 0.0 5.2 15.2 0.3 0.1 0.1 20.3 0.0 6.8 0.0 0.0 1.3 13.3 0.0 0.0 0.7 24.8 0.0 16.1 0.1 2.9 0.1 0.1 0.1 0.1 14.2 0.1 4.7 1.7 1.2 4.9 0.2 0.4 0.1 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 4.1 3.8 3.9 2.6 3.6 3.9 5.2 7.4 5.3 4.8 4.2 4.4 0.7 0.0 1.1 1.3 0.0 0.9 6.5 1.5 0.0 0.4 1.8 19.3 27.0 7.2 4.0 11.0 0.0 7.5 0.1 0.0 39.2 14.8 0.4 15.0 13.9 1.2 0.0 0.0 0.0 1.1 10.0 17.3 0.0 3.9 1.3 25.7 1.1 0.0 1.7 0.0 0.0 0.0 2.0 0.0 0.9 2.9 70.8 0.6 1.8 1.0 0.0 14.6 0.0 1.5 0.1 3.6 0.0 57.9 0.0 3.7 0.0 1.2 2.4 0.5 13.1 12.3 8.3 0.4 5.5 0.0 0.1 2.1 0.2 32.7 0.0 0.8 CCDC88C "DAPLE, HkRP2, KIAA1509, SCA40" ENSG00000015133 "Coiled-coil domain containing 88C" Q9P219 14 91271323-91417844 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Guanine-nucleotide releasing factor" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 33.9" "Cell type enhanced" "Detected in many" "dendritic cells: 80.1;NK-cells: 142.2;Plasma cells: 93.2;Respiratory ciliated cells: 112.5;T-cells: 89.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 55.6;Karpas-707: 50.1;SCLC-21H: 53.6;U-266/70: 58.5;U-266/84: 76.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "basal ganglia: 37.0" HPA005832 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Nucleoli fibrillar center" "HPA005832: AB_1079202" "unprognostic (7.28e-2)" "unprognostic (2.33e-3)" "unprognostic (7.23e-2)" "unprognostic (5.06e-2)" "unprognostic (1.00e-1)" "prognostic favorable (3.47e-4)" "unprognostic (3.07e-2)" "prognostic favorable (2.90e-4)" "unprognostic (1.48e-1)" "unprognostic (2.13e-1)" "unprognostic (4.77e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.80e-4)" "unprognostic (7.48e-2)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (4.35e-2)" 4.5 1.4 5.9 19.4 23.9 31.2 6.9 3.2 7.1 4.0 2.5 9.4 13.3 3.1 1.6 12.5 12.2 6.2 4.0 3.6 3.9 6.8 3.6 9.7 33.9 5.6 6.7 1.0 8.3 5.3 5.2 2.4 4.6 9.4 7.0 1.0 10.1 3.9 2.3 7.0 11.7 2.3 4.3 21.7 12.4 8.0 7.8 20.4 2.5 2.7 20.4 8.1 7.6 3.2 8.5 6.9 7.5 9.5 0.0 0.0 34.9 0.0 0.0 0.0 0.0 6.8 13.4 45.1 6.1 0.0 0.4 0.4 11.3 6.4 0.0 28.8 4.7 10.0 4.8 9.9 0.7 23.0 8.4 0.0 11.4 0.0 0.0 0.7 8.6 55.6 11.2 50.1 0.1 24.9 24.2 29.6 7.1 6.2 11.5 19.5 0.2 14.2 2.6 10.2 53.6 11.6 4.6 16.9 4.6 5.6 10.2 20.7 2.6 0.0 0.2 0.1 0.1 58.5 76.2 22.8 0.0 20.1 0.1 7.8 3.3 1.3 9.4 1.9 8.8 2.5 6.0 9.2 1.8 2.1 3.8 5.8 2.3 4.0 3.0 2.0 10.7 4.1 5.9 23.9 3.2 7.1 3.6 3.9 5.6 6.7 4.6 4.3 7.8 3.2 26.6 3.2 28.8 7.8 54.1 9.3 15.9 19.0 27.9 0.0 15.3 7.6 19.8 10.0 22.1 14.7 0.0 3.6 80.1 29.6 0.0 4.4 9.6 62.6 1.4 17.3 23.9 20.6 7.1 5.9 2.2 4.2 20.4 12.1 2.5 1.3 20.3 1.6 6.3 0.0 2.5 15.3 22.4 21.0 12.4 18.7 4.1 18.9 1.8 9.4 20.1 8.0 142.2 8.0 5.2 7.8 18.2 3.0 93.2 16.8 13.1 13.2 112.5 0.1 0.0 2.9 4.4 4.7 17.4 31.2 9.5 1.8 89.2 3.3 19.4 19.8 CCM2 "C7orf22, MGC4607, OSM" ENSG00000136280 "CCM2 scaffold protein" Q9BSQ5 7 44999475-45076469 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 140.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020273, HPA021669, HPA065815" Supported Enhanced Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "HPA020273: AB_1846185, HPA021669: AB_1846186, HPA065815: AB_2685562" "unprognostic (4.30e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (3.17e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (4.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.37e-3)" "unprognostic (3.92e-1)" "unprognostic (2.65e-1)" "prognostic favorable (1.16e-4)" "unprognostic (3.03e-1)" "prognostic unfavorable (5.06e-7)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (2.81e-2)" "unprognostic (2.48e-1)" 32.7 40.7 62.5 25.1 74.5 15.5 26.6 58.7 89.1 19.1 48.4 30.2 13.2 20.3 6.4 22.4 18.9 11.5 37.1 63.0 62.4 24.2 86.0 29.2 43.6 67.6 62.8 16.1 26.6 21.4 30.4 14.5 69.2 23.8 10.8 9.4 18.8 14.5 48.2 21.1 27.6 16.9 60.0 54.6 24.0 30.3 71.5 45.4 18.7 36.9 29.6 27.2 20.0 68.6 38.7 41.8 24.4 49.2 45.5 39.8 17.7 45.9 37.3 32.0 43.3 30.6 39.3 53.7 34.5 58.5 101.8 49.5 15.3 58.9 21.4 61.0 29.7 23.3 34.0 22.1 39.9 9.9 61.5 44.7 38.0 56.3 24.0 30.0 59.2 76.8 27.5 42.1 64.7 58.2 47.9 131.6 28.4 32.3 46.1 25.7 14.2 43.9 33.1 36.8 46.9 36.8 37.5 29.2 20.9 31.7 33.3 45.7 45.1 43.4 36.4 44.2 44.8 75.9 64.0 109.2 42.3 35.7 53.4 108.1 33.5 105.8 52.2 40.2 35.2 42.0 62.3 57.4 23.6 43.6 58.9 44.1 103.9 60.9 47.7 23.8 167.1 40.2 62.5 74.5 58.7 89.1 63.0 62.4 67.6 62.8 69.2 60.0 71.5 68.6 28.7 19.2 19.4 26.1 57.5 46.8 22.6 27.6 54.7 19.0 13.5 24.6 13.0 20.0 18.8 14.7 4.2 28.3 53.7 30.5 25.4 30.2 6.9 6.0 14.3 26.7 15.6 13.7 33.3 38.5 35.8 25.0 11.2 7.4 36.1 23.8 30.4 56.5 49.3 82.4 24.9 15.2 12.2 47.9 51.1 12.8 21.1 47.7 33.8 56.2 140.0 34.1 122.6 20.1 51.7 45.3 11.4 20.3 69.1 40.4 13.6 22.9 8.0 14.4 19.7 16.2 29.6 15.3 37.8 16.8 23.0 10.4 55.7 36.9 15.2 19.7 CCN6 "WISP-3, WISP3" ENSG00000112761 "Cellular communication network factor 6" O95389 6 112054075-112069686 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "epididymis: 10.2" "Cell type enriched" "Detected in single" 7 "Cardiomyocytes: 2.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 49 "RT4: 12.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA064196 Supported Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 15: RT4 - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria "HPA064196: AB_2685209" "unprognostic (2.13e-2)" "unprognostic (7.90e-3)" "unprognostic (5.00e-2)" "unprognostic (2.22e-2)" "unprognostic (3.76e-1)" "unprognostic (6.52e-2)" "unprognostic (1.98e-3)" "unprognostic (4.07e-3)" "unprognostic (1.82e-1)" "unprognostic (3.90e-1)" "unprognostic (1.02e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "unprognostic (3.11e-1)" "unprognostic (4.91e-2)" "unprognostic (2.93e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 10.2 0.0 2.3 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CCND1 "BCL1, D11S287E, PRAD1, U21B31" ENSG00000110092 "Cyclin D1" P24385 11 69641156-69654474 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Transcription, Transcription regulation" "Cyclin, Repressor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 499.7;Ductal cells: 504.0;Pancreatic endocrine cells: 622.1;Urothelial cells: 412.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/70: 874.2;WM-115: 1239.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000024, HPA027802" Uncertain Supported Nucleoplasm Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 18: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "CAB000024: AB_563678, HPA027802: AB_2672390" "unprognostic (4.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.38e-1)" "unprognostic (2.53e-2)" "unprognostic (9.46e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (4.39e-2)" "unprognostic (2.61e-3)" "unprognostic (4.38e-3)" "unprognostic (1.16e-1)" "unprognostic (6.40e-3)" "unprognostic (2.57e-1)" 55.6 29.2 12.1 10.0 14.6 1.5 40.2 15.0 11.9 17.0 33.4 19.8 22.7 14.8 27.6 72.9 30.8 19.5 64.9 10.8 14.6 32.2 107.3 61.1 10.5 17.5 15.5 4.6 86.3 82.7 25.7 63.7 18.3 53.3 17.2 3.2 30.4 50.4 3.6 120.3 16.0 23.3 15.9 37.2 52.7 3.2 21.7 9.9 45.5 5.2 19.0 29.5 43.9 24.0 467.3 183.0 59.5 1.8 178.3 186.7 127.4 717.5 264.9 82.1 47.6 206.9 349.9 0.1 317.6 375.5 137.2 332.1 6.5 195.2 146.0 1.2 36.5 0.3 46.7 211.7 43.3 3.3 6.7 106.5 37.9 116.0 44.0 192.5 142.1 0.2 0.6 1.3 654.2 197.1 0.4 26.6 109.0 190.7 198.3 1.2 187.9 11.3 379.4 282.8 10.0 231.4 9.2 167.7 458.4 143.5 102.6 9.5 600.4 399.5 111.0 176.1 496.2 874.2 559.4 1.5 341.6 5.9 1239.0 0.2 0.0 0.0 0.2 0.0 0.0 0.9 0.1 0.0 1.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.1 14.6 15.0 11.9 10.8 14.6 17.5 15.5 18.3 15.9 21.7 24.0 84.6 182.7 115.6 0.3 8.3 202.5 234.7 499.7 133.1 2.3 163.4 140.0 80.0 92.9 271.6 125.0 2.1 10.9 2.4 44.8 31.3 504.0 0.4 104.2 23.5 141.0 56.5 2.5 0.5 142.6 1.2 67.6 127.4 199.5 29.1 0.0 98.2 165.2 75.0 0.0 2.2 42.6 75.3 18.8 61.9 2.0 4.1 23.6 51.6 17.8 2.4 79.1 0.0 49.8 0.3 622.1 118.0 57.6 0.5 262.0 19.4 57.1 85.9 3.1 131.5 13.0 184.8 0.5 23.4 292.3 351.1 2.5 8.8 3.4 82.2 412.6 CCND2 ENSG00000118971 "Cyclin D2" P30279 12 4269771-4305353 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 354.3;Granulosa cells: 438.5;Langerhans cells: 255.3;Plasma cells: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 152.4;HBEC3-KT: 136.6;HDLM-2: 238.8;Karpas-707: 287.9;RH-30: 202.7;RPMI-8226: 114.2" "HPA049138, HPA054196" Approved Enhanced Nucleoplasm Yes Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA049138: AB_2680650, HPA054196: AB_2682412" "unprognostic (2.98e-3)" "unprognostic (1.15e-1)" "unprognostic (7.21e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-2)" "unprognostic (4.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.01e-3)" "unprognostic (3.16e-2)" "unprognostic (1.66e-2)" "prognostic favorable (2.52e-4)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (8.23e-2)" "unprognostic (4.52e-1)" "prognostic favorable (9.76e-5)" "unprognostic (7.06e-2)" 20.0 52.6 5.4 8.7 12.9 20.3 13.0 0.0 13.5 26.9 0.0 40.8 17.4 26.1 7.5 12.2 22.1 2.7 51.9 14.4 1.1 9.7 1.9 17.2 5.3 9.6 0.2 14.2 24.5 9.9 23.5 12.9 2.7 20.7 10.4 0.7 10.8 9.1 1.8 12.6 25.9 9.8 7.8 19.7 12.7 4.0 0.0 3.2 20.3 0.0 5.1 26.5 19.9 4.5 0.0 0.0 152.4 0.0 10.1 0.4 0.0 0.0 0.0 0.0 0.0 62.8 0.0 0.0 0.4 0.0 0.0 16.2 0.1 136.6 0.0 238.8 2.5 0.7 0.0 0.0 0.0 57.0 12.6 23.8 2.4 0.0 97.0 0.0 0.0 0.8 17.0 287.9 6.8 0.0 0.0 52.8 50.8 0.0 0.0 0.0 202.7 114.2 0.0 8.1 0.0 0.0 0.0 0.0 0.0 89.6 0.0 0.0 4.2 0.0 39.3 0.0 0.0 1.4 60.7 0.0 0.0 32.3 0.0 6.6 0.4 4.7 11.1 0.0 17.1 3.1 16.3 13.8 0.4 1.7 10.4 12.1 1.1 9.4 0.0 1.1 13.6 6.8 5.4 12.9 0.0 13.5 14.4 1.1 9.6 0.2 2.7 7.8 0.0 4.5 23.9 60.9 46.6 10.1 82.9 106.8 23.9 73.4 174.2 7.6 3.4 41.8 354.3 2.8 37.4 12.9 0.0 4.0 128.7 37.5 0.0 3.1 0.8 3.3 110.8 35.7 64.8 37.2 54.1 68.3 2.7 123.6 4.6 3.6 55.8 438.5 19.6 2.2 13.0 3.3 55.2 147.7 12.2 11.9 255.3 3.3 52.5 39.3 39.2 19.7 9.8 170.0 89.6 55.3 4.0 20.7 49.4 124.1 371.2 35.8 34.4 1.4 10.3 6.5 26.3 21.4 112.6 0.8 5.1 50.9 39.6 6.3 122.6 41.5 159.7 8.4 CCNQ "CycM, FAM58A" ENSG00000262919 "Cyclin Q" Q8N1B3 X 153587925-153600045 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 72.4;Extravillous trophoblasts: 98.6;Syncytiotrophoblasts: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050137, HPA059843" Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "HPA050137: AB_2681029, HPA059843: AB_2684140" "unprognostic (3.94e-1)" "unprognostic (1.94e-2)" "unprognostic (7.36e-2)" "unprognostic (2.92e-1)" "unprognostic (5.08e-2)" "unprognostic (1.02e-2)" "unprognostic (1.47e-3)" "unprognostic (2.12e-1)" "unprognostic (8.50e-3)" "unprognostic (2.08e-2)" "unprognostic (1.57e-2)" "unprognostic (1.90e-1)" "unprognostic (1.20e-1)" "unprognostic (8.75e-2)" "unprognostic (2.31e-1)" "unprognostic (2.71e-2)" "unprognostic (5.25e-2)" 11.8 12.8 19.9 8.2 21.3 7.3 11.7 19.6 24.9 11.9 15.6 16.2 8.9 12.9 12.7 13.1 11.1 4.0 33.9 20.8 20.5 13.5 13.2 10.6 12.5 23.2 21.6 10.5 15.0 10.3 23.6 9.2 23.4 13.6 8.0 6.4 12.9 8.8 34.3 12.1 13.6 6.1 20.0 17.2 13.3 6.2 21.2 9.0 11.1 13.6 12.2 14.0 11.7 24.9 43.7 31.2 12.1 43.5 20.9 11.2 18.7 25.0 21.8 23.5 23.6 33.3 14.3 34.9 44.6 25.1 35.3 26.7 38.4 22.6 22.2 20.3 39.2 7.8 19.4 23.5 19.0 28.2 18.9 14.1 20.1 15.7 16.1 10.0 19.0 16.1 10.6 15.6 19.1 50.5 19.7 38.0 15.1 44.4 52.4 22.6 20.0 17.8 17.0 17.6 16.0 21.1 12.0 19.3 34.4 11.9 7.3 25.0 14.6 20.5 29.3 46.7 38.5 21.8 23.1 43.4 18.5 45.4 15.7 0.0 1.6 4.9 2.7 1.4 1.0 6.1 2.3 1.9 1.3 4.1 2.5 1.7 0.9 0.7 0.8 1.2 3.4 1.1 19.9 21.3 19.6 24.9 20.8 20.5 23.2 21.6 23.4 20.0 21.2 24.9 21.0 3.2 13.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 24.1 31.0 0.0 0.0 3.1 7.3 0.0 40.7 20.4 0.0 72.4 23.3 0.0 11.9 17.3 7.8 0.0 0.0 0.0 37.1 98.6 8.4 0.0 8.7 2.5 16.3 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 22.7 0.0 0.0 0.0 0.0 34.0 0.0 0.0 5.9 0.0 0.0 41.6 2.2 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 120.9 10.0 18.4 0.0 0.0 CD96 TACTILE ENSG00000153283 "CD96 molecule" P40200 3 111292719-111665750 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.8" "Group enriched" "Detected in many" 4 "dendritic cells: 96.8;NK-cells: 58.7;T-cells: 199.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 74.0;MAIT T-cell: 117.2;memory CD4 T-cell: 67.0;memory CD8 T-cell: 85.3;naive CD4 T-cell: 68.7;naive CD8 T-cell: 81.8;NK-cell: 79.5;T-reg: 47.4" "Group enriched" "Detected in many" 5 "NK-cells: 79.5;T-cells: 117.2" "Cell line enhanced" "Detected in some" "HEL: 15.9;JURKAT: 18.2;MOLT-4: 68.7;RT4: 58.2;U-937: 59.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066754 Enhanced NA NA 85000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA066754: AB_2685714" "unprognostic (1.06e-3)" "unprognostic (3.95e-3)" "unprognostic (4.16e-3)" "unprognostic (1.91e-5)" "unprognostic (4.72e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.12e-2)" "unprognostic (3.48e-2)" "unprognostic (6.06e-2)" "unprognostic (4.84e-3)" "unprognostic (2.44e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.02e-6)" "unprognostic (3.12e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-2)" "prognostic favorable (5.23e-5)" 5.2 1.7 0.7 12.2 0.8 16.0 2.8 1.2 1.0 3.1 1.8 5.0 6.0 2.6 0.9 1.8 1.9 5.8 0.8 0.8 0.8 1.6 3.7 8.3 26.9 1.8 0.7 0.9 0.4 0.2 0.7 1.0 1.2 2.1 5.9 0.1 2.7 1.1 0.4 1.0 10.1 1.4 0.7 12.8 6.8 0.8 1.2 61.8 3.9 0.1 20.2 11.8 2.6 2.2 0.1 0.0 0.2 0.1 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.3 1.6 0.3 0.3 0.0 0.0 0.7 0.1 0.1 0.0 0.2 0.0 15.9 0.2 0.2 0.0 0.8 1.3 0.0 0.0 0.1 0.1 1.2 0.0 18.2 0.3 2.0 0.0 0.0 68.7 0.2 0.6 0.0 0.0 0.1 1.9 0.5 0.6 58.2 0.1 0.0 0.2 0.9 0.1 0.3 0.3 0.2 0.0 0.3 1.1 0.3 0.1 5.6 1.9 0.0 0.3 59.0 12.2 2.3 0.5 15.6 74.0 0.3 117.2 10.8 67.0 85.3 0.3 18.8 68.7 81.8 2.7 79.5 0.7 0.5 47.4 46.4 0.7 0.8 1.2 1.0 0.8 0.8 1.8 0.7 1.2 0.7 1.2 2.2 1.5 19.2 19.0 0.0 12.5 3.2 0.8 0.1 1.2 1.6 1.6 1.4 1.0 0.0 9.3 1.8 0.0 0.6 96.8 0.8 0.0 0.1 0.8 2.1 0.8 3.0 0.0 9.3 0.7 0.0 0.2 4.3 8.6 1.6 16.4 0.4 2.2 0.9 0.2 0.0 0.4 0.7 0.0 5.0 6.7 1.1 0.3 6.7 3.6 6.5 2.9 0.5 58.7 0.0 0.1 0.0 1.3 0.0 29.6 0.3 0.0 0.4 1.7 2.1 0.0 0.8 1.0 0.4 0.7 0.6 3.1 1.9 199.9 0.2 0.5 0.6 CDC45 "CDC45L, CDC45L2" ENSG00000093009 "Cell division cycle 45" O75419 22 19479457-19520612 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;lymphoid tissue: 20.4;testis: 23.4" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Erythroid cells: 29.7;Spermatocytes: 72.3;Spermatogonia: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "K-562: 370.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000614, CAB009459" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Centrosome, Cytosol" "CAB009459: AB_2078507, HPA000614: AB_1078487" "unprognostic (5.56e-2)" "unprognostic (6.12e-3)" "unprognostic (1.17e-3)" "unprognostic (3.42e-3)" "unprognostic (3.57e-1)" "unprognostic (7.42e-2)" "prognostic unfavorable (6.95e-6)" "unprognostic (6.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (8.94e-4)" "unprognostic (7.28e-2)" "unprognostic (0.00e+0)" "unprognostic (7.62e-3)" "unprognostic (2.02e-1)" "unprognostic (8.52e-2)" "unprognostic (1.10e-1)" 0.5 0.5 0.7 6.2 0.5 25.4 1.5 0.2 0.2 1.1 0.4 4.6 3.5 0.9 0.3 5.3 0.4 0.5 0.3 0.2 0.4 0.3 1.2 0.9 11.3 0.5 0.4 0.2 0.2 0.2 0.1 3.2 0.5 0.4 6.0 0.1 0.9 0.2 0.1 3.3 3.1 1.8 0.2 2.8 2.6 23.4 1.1 20.4 0.3 0.0 11.8 1.9 1.7 0.3 57.4 42.2 56.4 42.9 2.0 5.6 24.4 65.4 31.6 75.5 75.5 35.8 30.5 62.2 23.2 21.0 28.9 51.9 58.2 45.9 59.5 72.3 96.3 82.8 50.1 41.3 3.1 125.0 43.7 1.3 2.4 57.9 26.0 7.0 38.8 63.0 370.6 73.3 44.8 77.2 98.1 56.5 16.7 106.2 34.4 77.1 95.5 26.5 16.9 49.3 72.1 37.0 38.1 40.0 12.0 21.7 26.2 51.0 15.0 60.0 91.6 46.0 62.8 24.6 46.8 67.5 30.1 58.9 82.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.7 0.1 0.0 0.2 0.1 0.5 0.5 0.1 0.3 0.9 0.6 0.7 0.5 0.2 0.2 0.2 0.4 0.5 0.4 0.5 0.2 1.1 0.3 0.2 0.0 0.0 0.0 1.9 2.7 1.7 3.7 0.0 0.0 0.7 0.8 0.4 0.0 0.5 0.0 0.0 11.9 1.4 1.9 0.0 0.8 120.5 0.9 0.7 1.2 0.0 29.7 0.1 0.0 19.8 2.3 1.5 1.0 0.0 5.5 3.6 0.0 7.2 0.0 0.1 1.2 4.1 0.6 1.0 14.4 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.7 12.6 0.2 0.4 0.0 0.3 0.0 6.6 1.5 13.9 72.3 50.7 3.3 1.8 4.9 1.2 0.8 5.1 2.5 CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287879-40304657 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.2;lymphoid tissue: 17.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.2;Erythroid cells: 37.2;Extravillous trophoblasts: 34.6;Plasma cells: 31.6;Spermatocytes: 69.5;Spermatogonia: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;NK-cells: 1.5;T-cells: 2.4" "Cell line enhanced" "Detected in all" "SK-BR-3: 500.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: AB_2681021, HPA065070: AB_2732729" "unprognostic (1.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.97e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (5.96e-8)" "unprognostic (2.31e-3)" "unprognostic (1.46e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (5.47e-2)" "unprognostic (3.00e-15)" "unprognostic (1.86e-2)" "unprognostic (1.35e-1)" "unprognostic (3.95e-3)" "unprognostic (3.88e-2)" 2.1 1.9 0.5 13.7 0.8 27.2 3.4 0.2 1.9 3.2 0.0 8.4 7.5 2.2 1.1 5.7 1.0 2.8 0.6 1.1 0.1 0.5 3.0 1.4 16.4 0.1 0.0 0.9 1.9 0.8 0.5 9.3 0.3 1.1 8.7 0.5 1.3 1.2 0.3 2.8 6.7 3.7 0.0 3.7 3.6 10.1 0.2 16.7 1.7 0.5 17.1 4.3 1.8 0.6 155.1 119.0 115.1 86.5 6.7 12.7 118.0 159.9 49.0 149.2 166.5 135.8 64.9 123.9 99.6 35.9 85.9 214.0 112.2 76.2 148.9 64.5 98.4 96.2 122.3 134.6 4.4 133.3 55.1 4.7 8.1 156.4 107.1 14.8 46.9 84.2 183.0 109.0 71.9 95.8 199.3 43.3 101.6 96.9 48.7 145.0 286.8 119.9 30.3 184.8 85.6 76.9 146.9 500.3 55.4 100.3 100.8 120.0 34.7 95.5 146.3 170.8 196.1 46.1 103.6 222.8 84.6 93.9 109.2 0.1 0.1 0.0 0.8 0.0 0.5 0.4 0.6 1.1 0.7 0.3 0.4 1.1 0.1 1.5 0.0 3.6 2.4 0.6 0.5 0.8 0.2 1.9 1.1 0.1 0.1 0.0 0.3 0.0 0.2 0.6 2.2 0.0 2.0 0.7 4.9 4.2 1.1 3.7 3.4 0.2 2.1 2.2 0.9 1.5 1.3 0.0 0.0 23.2 2.3 7.8 0.0 1.3 2.2 1.3 2.9 2.1 0.0 37.2 2.0 0.6 34.6 5.6 3.6 5.1 0.0 8.1 1.1 0.9 8.3 0.0 0.7 6.1 0.0 1.3 2.1 1.0 2.8 1.5 0.0 0.0 0.0 0.4 2.1 0.0 0.2 1.5 3.0 0.7 31.6 1.3 0.8 0.2 0.2 0.3 13.1 0.6 4.6 69.5 57.2 9.1 1.6 16.7 3.3 1.9 9.3 2.4 CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 197.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 451.6;Glandular and luminal cells: 321.0;Pancreatic endocrine cells: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Cell line enhanced" "Detected in many" "BEWO: 683.3;CACO-2: 241.9;CAPAN-2: 328.1;HaCaT: 318.7;hTCEpi: 217.2;MCF7: 199.6;OE19: 207.2;RT4: 237.7;T-47d: 209.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 78000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" 1.0 0.2 1.5 16.1 2.0 6.5 64.2 0.6 1.9 30.0 19.3 127.5 133.9 9.6 39.5 76.9 51.5 45.7 0.3 1.5 1.3 39.8 97.2 36.8 5.6 2.0 1.3 1.3 84.0 197.8 8.0 60.9 1.3 91.7 131.0 0.1 71.9 41.7 0.3 107.7 127.9 5.1 2.1 10.3 104.2 0.4 2.3 20.1 162.7 0.1 29.0 58.2 38.1 2.7 147.0 14.8 0.0 0.5 0.0 0.0 683.3 0.0 0.0 0.0 0.0 241.9 328.1 0.0 3.1 0.0 0.0 318.7 0.0 156.3 0.0 28.6 3.5 0.1 0.7 48.0 0.0 0.0 0.6 0.0 217.2 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 199.6 0.2 1.0 5.5 207.2 0.8 0.1 0.1 2.1 53.9 237.7 8.5 0.8 1.4 0.2 58.9 91.8 209.2 0.4 0.0 0.4 0.9 0.7 0.6 0.1 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.1 1.5 2.0 0.6 1.9 1.5 1.3 2.0 1.3 1.3 2.1 2.3 2.7 0.6 131.4 69.8 0.7 1.4 94.1 130.3 73.8 45.5 0.0 137.6 83.6 0.9 128.7 95.3 163.7 0.0 117.6 2.5 451.6 1.9 129.1 0.1 159.3 29.2 4.4 86.7 9.0 0.7 113.5 29.6 3.4 132.0 321.0 1.3 2.8 0.4 63.4 11.7 0.0 1.4 208.3 75.3 1.2 13.4 0.0 0.3 3.2 53.4 1.0 3.3 0.0 0.0 0.5 32.1 264.6 204.6 0.4 2.2 195.5 159.5 4.5 118.2 0.0 0.0 0.0 7.1 0.1 0.1 100.6 131.6 50.5 2.7 0.0 154.8 251.5 CDH2 "CD325, CDHN, NCAD" ENSG00000170558 "Cadherin 2" P19022 18 27932879-28177946 "CD markers, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 196.0" "Cell type enhanced" "Detected in many" "Astrocytes: 217.7;Cardiomyocytes: 368.8;Excitatory neurons: 311.2;Granulosa cells: 312.5;Inhibitory neurons: 198.2;Muller glia cells: 157.9;Oligodendrocyte precursor cells: 267.9" "Cancer enhanced" "Detected in all" "glioma: 39.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.7;neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Cell line enhanced" "Detected in many" "AF22: 278.2;BJ: 230.7;fHDF/TERT166: 459.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000141, CAB018580, HPA058574, CAB078686" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 160000000 "Cluster 10: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB000141: , CAB018580: AB_626778, CAB078686: AB_2665849, HPA058574: AB_2683760" "unprognostic (9.42e-2)" "unprognostic (2.69e-3)" "unprognostic (9.07e-3)" "unprognostic (5.45e-2)" "unprognostic (1.14e-1)" "unprognostic (9.30e-2)" "unprognostic (3.97e-2)" "unprognostic (2.53e-3)" "unprognostic (6.70e-3)" "unprognostic (1.00e-2)" "unprognostic (7.53e-2)" "unprognostic (3.51e-2)" "unprognostic (3.02e-2)" "unprognostic (1.93e-3)" "unprognostic (6.69e-2)" "unprognostic (1.33e-1)" "unprognostic (2.59e-3)" 0.6 66.5 27.4 2.6 29.0 0.2 0.3 20.6 31.6 6.6 7.9 4.8 0.8 6.2 1.1 0.4 10.5 3.1 196.0 30.0 31.6 18.1 57.2 1.0 1.9 21.7 26.3 6.7 0.9 29.8 8.1 0.4 20.1 2.4 1.1 60.3 0.4 10.8 0.4 0.3 1.4 6.8 24.1 13.5 5.9 44.4 33.3 3.8 6.2 2.2 1.6 1.1 2.7 22.7 0.3 25.8 278.2 0.3 48.1 7.8 0.2 230.7 72.0 94.9 80.8 0.1 0.4 0.0 128.3 459.1 46.0 36.7 50.0 0.2 130.4 0.4 35.8 0.0 66.8 86.7 48.0 0.0 0.1 4.6 0.4 198.6 37.4 212.9 84.0 15.4 0.0 0.1 77.8 0.0 59.4 0.1 43.8 0.1 30.5 0.2 37.1 45.6 0.1 9.9 83.4 144.4 0.1 0.2 26.8 116.8 0.3 0.5 11.6 206.6 63.6 2.9 181.6 0.2 0.3 0.3 40.6 0.2 163.0 1.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 27.4 29.0 20.6 31.6 30.0 31.6 21.7 26.3 20.1 24.1 33.3 22.7 0.8 0.0 0.6 217.7 1.2 0.3 0.0 3.4 0.0 38.7 1.6 0.4 368.8 67.2 1.2 11.0 150.1 0.1 0.0 0.0 0.0 12.9 53.2 1.4 15.2 9.8 0.0 6.1 311.2 0.4 0.0 16.7 0.0 2.6 0.0 312.5 12.5 125.3 0.3 3.3 198.2 0.0 2.0 2.2 0.4 17.7 2.1 1.2 3.6 106.8 0.1 157.9 0.0 267.9 138.6 19.2 0.0 12.8 0.0 0.1 0.0 47.5 1.7 99.9 6.6 0.4 45.8 4.8 24.1 0.0 0.0 0.3 0.6 1.6 0.0 0.1 CDH3 "CDHP, PCAD" ENSG00000062038 "Cadherin 3" P22223 16 68636189-68727468 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;ovary: 32.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 60.8;Basal prostatic cells: 67.2;Basal respiratory cells: 161.4;Basal squamous epithelial cells: 71.7;Granulosa cells: 77.6;Melanocytes: 60.5;Pancreatic endocrine cells: 85.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 100.6;HaCaT: 263.9;HBEC3-KT: 126.9;hTCEpi: 94.3;hTERT-HME1: 72.7;RPTEC TERT1: 116.8" "Region enhanced" "Detected in single" "olfactory bulb: 1.7" "Low region specificity" "Detected in all" "HPA001767, CAB002487" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 510000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "Cell Junctions" "CAB002487: AB_563446, HPA001767: AB_1078376" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (1.33e-1)" "unprognostic (4.38e-3)" "unprognostic (6.73e-2)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "prognostic unfavorable (8.53e-4)" "unprognostic (1.22e-1)" "unprognostic (3.45e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (4.30e-2)" "unprognostic (2.41e-5)" "unprognostic (2.11e-1)" "unprognostic (1.09e-1)" "unprognostic (1.33e-3)" "unprognostic (8.56e-2)" 3.6 0.2 1.3 3.4 1.5 0.1 8.2 1.9 1.6 9.7 47.1 0.4 0.5 10.0 8.8 26.8 12.0 1.5 0.3 3.5 0.8 6.0 0.0 2.0 2.5 1.2 1.0 32.7 0.6 1.5 4.4 4.5 0.6 13.6 0.7 0.8 12.4 4.6 0.2 25.8 0.7 4.0 1.9 10.9 1.0 1.6 1.1 18.8 1.2 0.0 11.7 3.9 11.2 1.1 100.6 0.2 0.9 0.1 0.1 0.0 8.6 0.0 0.0 0.3 0.1 61.4 36.6 0.0 0.4 0.0 0.2 263.9 2.6 126.9 0.4 0.0 1.2 0.0 0.2 0.0 0.2 0.2 0.5 0.0 94.3 0.1 72.7 0.3 0.0 0.0 0.0 0.2 0.0 48.8 0.1 0.1 5.3 0.9 8.8 0.0 0.0 0.0 116.8 44.5 0.5 0.2 0.8 0.0 50.0 45.6 29.2 0.2 0.0 0.0 0.2 0.0 0.3 0.1 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 1.6 3.5 0.8 1.2 1.0 0.6 1.9 1.1 1.1 0.2 16.0 4.6 0.7 0.0 60.8 67.2 161.4 71.7 1.2 6.8 39.2 1.4 0.0 35.9 14.7 2.1 23.4 0.5 0.5 0.0 35.7 0.5 0.9 8.2 1.3 1.2 0.0 6.0 32.1 2.1 3.7 0.0 0.9 1.3 77.6 0.0 0.0 2.8 0.0 9.1 1.5 20.3 0.0 1.9 0.2 0.6 0.7 60.5 0.0 1.0 0.4 1.0 3.0 2.2 85.7 0.1 9.4 1.2 44.5 0.0 0.1 12.6 0.5 0.0 0.6 5.9 0.4 1.0 26.5 30.7 6.3 1.2 0.1 1.5 43.1 CDK10 PISSLRE ENSG00000185324 "Cyclin dependent kinase 10" Q15131 16 89680737-89696354 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007451, HPA059634, HPA067060" Uncertain Supported "Nucleoplasm,Midbody,Midbody ring" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Midbody, Midbody ring" "HPA007451: AB_2732400, HPA059634: AB_2684090, HPA067060: AB_2685772" "unprognostic (7.89e-2)" "unprognostic (8.08e-2)" "unprognostic (3.74e-3)" "unprognostic (9.87e-2)" "unprognostic (1.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.53e-1)" "unprognostic (9.06e-2)" "unprognostic (2.99e-1)" "unprognostic (2.13e-1)" "prognostic favorable (2.69e-4)" "unprognostic (2.58e-2)" "unprognostic (2.93e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (6.88e-2)" "prognostic favorable (3.63e-4)" 30.1 38.5 20.2 10.4 20.4 19.5 26.7 20.3 32.8 49.3 22.0 38.2 22.7 25.9 8.7 35.3 36.3 8.6 27.3 21.0 19.5 52.9 77.0 31.0 14.7 18.6 18.7 43.2 49.2 13.5 55.5 12.5 19.6 39.1 11.3 7.6 24.8 7.5 33.8 32.1 36.1 8.2 17.0 37.5 38.5 17.0 18.4 10.8 54.5 4.1 7.0 32.3 36.5 19.1 27.5 17.8 13.9 5.8 5.7 11.0 14.2 22.3 12.6 15.2 4.9 13.1 21.2 23.9 9.8 19.3 9.1 15.5 5.8 30.8 9.3 5.3 14.1 9.7 21.0 1.7 23.4 15.8 17.1 13.3 10.7 9.3 15.3 10.3 27.0 16.1 25.5 3.2 17.7 36.6 19.5 45.0 28.5 29.7 13.1 26.5 19.0 34.1 27.9 21.2 10.1 29.6 28.0 13.0 6.8 15.2 30.3 25.0 24.1 9.1 26.6 10.1 15.4 11.7 6.4 7.5 16.4 25.0 15.5 5.1 14.0 4.2 14.8 19.7 12.8 7.8 13.2 10.7 18.1 9.0 15.1 12.6 1.5 20.4 15.4 12.4 11.6 11.4 20.2 20.4 20.3 32.8 21.0 19.5 18.6 18.7 19.6 17.0 18.4 19.1 28.2 12.8 26.6 35.3 21.2 15.4 24.2 26.9 23.3 17.2 24.5 25.1 6.5 38.6 20.0 27.6 25.0 28.6 26.7 44.8 43.0 28.6 6.1 20.7 21.9 23.0 67.7 15.4 44.5 12.5 19.8 19.6 85.1 16.9 9.5 40.3 21.8 41.1 18.8 18.5 33.3 49.4 26.4 17.4 16.0 8.8 23.9 17.0 19.6 17.8 15.5 8.5 26.8 24.6 20.0 13.6 41.5 12.4 20.8 30.7 58.3 53.7 28.1 32.3 6.6 11.4 16.3 27.3 28.7 22.4 15.5 27.9 22.0 54.8 58.2 22.9 CDK13 "CDC2L, CDC2L5, CHED, KIAA1791" ENSG00000065883 "Cyclin dependent kinase 13" Q14004 7 39950121-40099580 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 179.0;Oligodendrocyte precursor cells: 171.9;Oligodendrocytes: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059241 Uncertain Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Golgi apparatus, Cytosol" "HPA059241: AB_2683956" "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (2.72e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (4.18e-3)" "unprognostic (3.42e-2)" "unprognostic (8.09e-2)" "unprognostic (1.13e-2)" "unprognostic (3.77e-2)" "unprognostic (8.13e-2)" "unprognostic (8.20e-2)" "unprognostic (1.21e-1)" "unprognostic (3.33e-2)" "unprognostic (3.53e-1)" "unprognostic (3.53e-2)" 11.4 10.2 8.8 14.6 10.8 28.1 11.1 19.3 9.9 12.8 6.7 11.9 10.5 13.6 14.2 14.7 15.0 12.7 10.4 8.1 10.7 12.7 15.9 12.1 21.7 10.5 8.5 20.1 12.8 17.2 8.0 13.6 8.6 11.2 13.6 19.7 12.9 11.8 11.2 12.0 12.0 12.0 7.2 16.6 12.3 19.0 10.1 19.6 20.6 14.0 20.2 13.4 10.0 14.9 28.4 16.6 28.2 27.0 24.9 24.1 19.3 22.1 23.8 19.8 24.6 17.8 19.1 51.0 12.6 23.4 34.8 33.6 23.4 19.4 29.0 25.3 17.3 22.8 20.0 16.0 23.7 34.8 23.5 14.3 25.5 22.6 30.0 22.6 23.6 23.1 39.0 34.3 20.7 14.7 28.0 24.9 40.8 20.0 19.1 30.5 18.5 20.5 18.5 28.1 20.0 28.8 27.6 59.8 19.9 36.7 24.6 43.0 28.3 27.0 26.0 17.6 30.5 28.3 26.0 41.2 19.8 30.9 35.4 7.8 2.2 4.0 4.1 1.9 2.8 6.4 3.8 3.0 1.3 10.5 3.8 3.9 5.9 4.3 3.1 3.3 3.9 1.3 8.8 10.8 19.3 9.9 8.1 10.7 10.5 8.5 8.6 7.2 10.1 14.9 47.6 44.8 72.0 131.6 49.7 21.4 18.5 15.9 29.0 47.8 36.7 27.7 30.9 25.8 37.1 31.3 70.9 13.7 91.0 23.1 7.9 20.4 13.9 54.3 51.4 30.9 18.7 5.9 179.0 15.4 9.1 31.7 30.1 72.6 17.1 95.5 19.2 23.7 13.2 37.0 166.2 17.6 14.2 23.8 17.4 9.2 26.1 31.6 14.2 145.2 27.9 22.4 53.5 171.9 199.6 28.6 12.9 17.7 50.1 21.8 15.2 12.7 32.8 69.4 6.6 38.5 32.0 36.1 33.4 34.7 26.1 12.2 49.7 56.8 20.1 25.0 CDK5 PSSALRE ENSG00000164885 "Cyclin dependent kinase 5" Q00535 7 151053815-151057897 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008909, HPA064535" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB008909: , HPA064535: AB_2685280" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (4.22e-2)" "unprognostic (1.43e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-1)" "unprognostic (5.67e-3)" "unprognostic (1.05e-2)" "unprognostic (1.22e-1)" "unprognostic (5.78e-3)" "unprognostic (6.25e-3)" "unprognostic (3.35e-1)" "unprognostic (4.47e-2)" "unprognostic (1.46e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" "unprognostic (1.11e-1)" 6.3 16.8 50.2 9.4 53.2 11.2 8.6 44.9 65.8 8.6 40.0 9.3 10.9 6.7 24.9 10.2 8.2 9.5 9.8 57.5 50.9 13.5 12.5 8.3 9.8 48.6 45.3 4.5 9.5 22.8 14.7 8.6 48.4 8.8 9.9 11.3 9.6 10.2 8.5 9.5 8.6 10.4 43.2 9.4 7.9 4.9 50.1 14.2 10.0 7.2 11.6 8.8 6.0 50.9 31.9 40.8 37.3 59.7 48.8 36.1 17.8 24.4 41.7 47.9 40.3 31.2 31.0 34.7 71.3 31.8 63.5 23.5 67.8 40.6 22.6 24.9 43.3 38.2 32.4 30.7 31.6 29.0 64.4 37.9 28.7 39.0 13.5 62.8 38.8 57.6 36.3 24.0 50.7 68.4 76.4 57.9 39.3 57.2 80.5 38.9 14.8 41.5 46.2 27.9 23.0 97.8 30.9 37.7 43.8 36.0 18.6 25.9 22.7 42.2 10.3 31.2 39.2 52.1 61.4 13.7 66.4 46.5 75.8 18.9 39.4 20.1 13.5 46.2 11.1 13.3 12.8 13.6 44.7 12.8 9.8 11.8 5.7 19.9 36.4 26.9 31.9 23.8 50.2 53.2 44.9 65.8 57.5 50.9 48.6 45.3 48.4 43.2 50.1 50.9 7.6 0.0 6.0 1.6 6.2 3.6 8.2 18.0 6.2 12.1 9.6 10.4 3.1 8.6 14.7 11.0 2.1 26.8 5.4 8.0 39.2 21.4 0.8 14.9 10.9 8.9 9.0 12.2 5.8 18.9 12.3 7.6 9.7 9.3 30.5 23.6 7.9 11.1 41.9 0.0 6.4 8.9 18.3 21.9 6.2 1.3 4.7 16.6 10.6 1.9 19.9 12.6 12.3 1.5 3.7 22.8 15.0 11.3 12.4 4.3 20.2 35.7 14.4 7.1 6.6 4.5 13.1 3.9 11.2 11.4 6.3 9.0 7.3 14.2 9.5 9.0 CDK5RAP2 "C48, CEP215, FLJ10867, MCPH3" ENSG00000136861 "CDK5 regulatory subunit associated protein 2" Q96SN8 9 120388869-120580170 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 148.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 15.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035820, HPA035821, HPA046529, CAB079753" Approved Enhanced "Cell Junctions,Centrosome" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Cell Junctions" "CAB079753: AB_2665827, HPA035820: AB_10671939, HPA035821: , HPA046529: AB_2679688" "unprognostic (7.72e-2)" "unprognostic (2.04e-2)" "unprognostic (2.84e-2)" "unprognostic (4.48e-2)" "unprognostic (6.63e-2)" "unprognostic (6.88e-2)" "unprognostic (6.70e-3)" "unprognostic (1.31e-1)" "unprognostic (1.71e-1)" "unprognostic (1.00e-1)" "unprognostic (7.36e-2)" "unprognostic (2.26e-2)" "unprognostic (1.88e-1)" "unprognostic (4.94e-2)" "unprognostic (2.36e-1)" "unprognostic (3.33e-2)" "unprognostic (7.41e-2)" 10.6 11.7 12.4 9.8 18.0 24.4 14.4 14.1 12.7 14.2 20.6 15.1 5.6 11.5 7.7 12.1 11.9 9.2 17.6 12.5 12.9 8.0 15.7 10.6 15.1 15.4 16.2 17.1 9.5 13.3 12.2 8.6 15.1 13.7 8.6 12.9 22.2 10.5 47.9 16.0 11.0 10.4 13.6 11.5 12.9 20.8 14.9 20.9 11.6 29.6 14.7 12.5 11.1 17.2 19.6 33.8 45.9 27.8 19.3 28.4 24.6 24.6 18.9 27.3 25.4 26.8 25.1 36.3 11.1 24.3 18.7 42.1 36.5 28.3 26.1 29.3 14.7 31.0 62.1 47.7 18.1 38.5 19.9 51.4 18.5 24.3 31.8 20.6 24.1 43.0 29.2 30.6 36.4 44.2 41.8 24.7 42.6 41.5 25.3 40.3 54.5 17.1 19.5 15.4 29.9 34.3 42.9 23.3 28.8 19.7 54.6 26.3 16.1 23.6 25.7 28.0 28.4 22.2 33.4 39.7 24.6 24.4 50.8 15.7 1.7 3.0 3.4 1.7 3.3 5.0 3.2 3.2 1.0 5.8 2.6 2.7 2.4 4.0 4.7 2.2 2.9 1.8 12.4 18.0 14.1 12.7 12.5 12.9 15.4 16.2 15.1 13.6 14.9 17.2 11.6 28.9 39.5 64.9 21.2 7.0 13.5 11.9 13.1 23.7 18.0 17.5 53.8 15.7 19.3 1.8 16.7 13.2 25.8 12.3 7.9 12.6 37.5 24.8 18.1 13.7 8.4 35.3 43.2 14.3 12.7 20.4 10.7 23.7 17.1 41.4 8.6 22.2 10.8 18.5 38.4 12.1 18.3 9.4 8.6 30.6 22.1 25.8 12.4 26.2 13.2 20.4 24.7 66.9 148.7 11.8 8.1 23.3 27.7 9.5 5.6 4.6 35.0 28.9 32.9 43.6 22.3 58.4 36.4 17.8 6.8 7.3 23.1 23.0 11.6 7.7 CDK6 PLSTIRE ENSG00000105810 "Cyclin dependent kinase 6" Q00534 7 92604921-92836573 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 41.1" "Cell type enhanced" "Detected in many" "Early spermatids: 215.9;Erythroid cells: 213.5;Late spermatids: 237.0;Oligodendrocytes: 235.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MOLT-4: 378.4;REH: 173.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002637, CAB004363" Enhanced Supported Nucleoplasm,Cytosol NA NA 26000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "CAB004363: AB_627242, HPA002637: AB_1846432" "unprognostic (1.29e-1)" "unprognostic (5.98e-3)" "unprognostic (9.07e-2)" "unprognostic (2.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.24e-2)" "unprognostic (3.39e-1)" "unprognostic (2.42e-3)" "unprognostic (7.19e-2)" "unprognostic (7.78e-3)" "prognostic unfavorable (3.86e-6)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.09e-1)" "unprognostic (7.88e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (2.33e-5)" 3.7 7.3 6.7 4.7 7.1 18.1 4.9 5.4 5.1 4.8 2.6 5.9 6.1 3.1 2.1 4.2 2.9 3.6 4.7 4.0 5.0 4.4 5.9 4.1 6.6 6.3 6.7 2.7 6.2 9.9 1.7 17.3 6.3 3.0 7.5 0.5 5.7 4.2 1.0 6.8 7.2 3.2 5.8 4.9 9.1 3.3 9.6 41.1 2.4 2.3 6.2 3.8 4.6 8.8 27.1 11.3 34.9 23.9 10.6 11.5 5.8 27.2 18.4 14.3 13.5 34.7 20.9 21.7 14.4 19.9 8.4 15.8 20.8 42.6 34.4 43.0 10.6 50.8 23.3 34.7 6.3 33.0 2.7 11.5 23.1 17.9 90.8 13.4 5.6 75.1 49.3 55.5 26.7 5.9 378.4 3.8 9.8 37.4 9.1 173.7 112.0 36.4 20.3 0.7 18.1 113.8 3.7 9.8 17.1 26.0 0.6 54.9 19.3 44.1 63.7 18.0 54.2 27.4 0.5 27.6 6.9 112.1 60.8 0.9 0.2 0.6 0.6 0.4 0.9 0.2 0.6 0.8 0.5 0.3 0.7 0.7 0.1 0.7 0.4 0.9 0.3 0.3 6.7 7.1 5.4 5.1 4.0 5.0 6.3 6.7 6.3 5.8 9.6 8.8 38.6 25.6 3.7 2.9 17.7 60.3 23.5 55.0 62.6 0.4 20.7 21.2 18.1 22.8 32.8 22.0 0.0 53.8 30.5 12.1 9.8 37.0 215.9 3.1 29.0 30.7 16.8 213.5 114.7 23.3 5.3 28.5 42.3 6.9 25.3 39.2 11.4 27.0 16.0 0.0 60.3 63.7 28.5 23.0 48.6 237.0 5.0 27.6 19.6 108.7 22.4 0.8 39.1 119.6 235.3 94.7 22.8 3.4 85.3 47.1 20.1 8.2 11.9 0.0 6.6 100.8 32.2 2.7 33.6 36.7 50.4 17.6 42.5 62.8 92.7 27.3 CDKN1C "BWCR, BWS, KIP2, P57" ENSG00000129757 "Cyclin dependent kinase inhibitor 1C" P49918 11 2883213-2885775 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 206.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 575.3;Extravillous trophoblasts: 1531.7;Syncytiotrophoblasts: 2241.2;Theca cells: 781.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 155.1;non-classical monocyte: 376.4" "Lineage enriched" "Detected in many" 14 "monocytes: 376.4" "Cell line enhanced" "Detected in many" "EFO-21: 12.0;HeLa: 12.8;RPMI-8226: 18.7;SH-SY5Y: 33.0;SiHa: 25.2;SK-MEL-30: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002924 Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Nuclear bodies" Cytosol "HPA002924: AB_1079548" "unprognostic (5.49e-3)" "unprognostic (2.62e-1)" "unprognostic (9.82e-3)" "unprognostic (5.79e-3)" "unprognostic (4.15e-1)" "unprognostic (2.84e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-1)" "unprognostic (3.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.95e-1)" "unprognostic (3.39e-2)" "unprognostic (2.15e-1)" "unprognostic (3.31e-2)" "unprognostic (8.53e-2)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" 127.4 182.9 8.2 3.3 38.0 1.7 92.5 43.3 18.7 73.7 6.5 48.1 1.4 70.6 0.2 29.9 70.7 0.8 82.6 11.7 18.8 149.5 8.3 34.5 0.2 55.1 33.5 206.4 28.5 0.2 27.8 28.1 45.0 33.1 0.2 0.5 21.7 1.5 60.3 26.6 25.0 0.4 31.8 20.6 54.1 8.6 34.3 0.2 17.0 0.9 0.4 75.0 49.4 95.3 0.1 0.1 1.6 0.0 0.4 0.5 1.8 0.3 0.6 0.3 0.0 3.3 0.4 0.0 12.0 0.2 0.1 0.5 0.3 0.3 0.1 5.6 1.2 0.1 12.8 0.0 3.3 0.0 1.4 2.4 1.6 0.0 0.2 0.1 0.3 0.1 2.7 0.8 0.5 0.1 0.0 6.0 10.6 0.5 4.0 2.2 0.0 18.7 0.7 0.0 3.5 33.0 25.2 0.3 15.2 0.9 0.2 2.8 0.4 0.0 2.2 0.0 0.1 7.3 0.0 0.1 0.0 1.8 6.8 9.1 1.2 0.9 0.4 155.1 1.8 0.0 0.4 0.6 26.9 0.3 1.0 0.3 2.2 0.0 376.4 0.2 0.7 14.7 8.2 38.0 43.3 18.7 11.7 18.8 55.1 33.5 45.0 31.8 34.3 95.3 357.3 3.2 5.8 1.0 11.6 10.7 81.7 4.9 30.7 11.9 81.0 150.5 45.3 61.5 10.8 31.3 6.2 575.3 46.9 20.3 15.6 9.8 176.5 38.8 101.5 100.8 106.5 0.8 0.6 0.6 1531.7 141.0 17.9 56.2 0.0 31.2 74.6 4.0 91.0 8.4 1.2 25.0 12.2 23.5 23.2 276.4 74.3 54.9 35.6 4.7 14.1 68.3 0.0 3.5 65.7 4.3 4.2 44.4 12.9 64.6 4.0 78.5 7.5 27.4 32.9 238.3 71.4 2.1 3.5 17.3 11.8 2241.2 25.1 781.8 15.2 71.8 CDON "CDO, CDON1, ORCAM" ENSG00000064309 "Cell adhesion associated, oncogene regulated" Q4KMG0 11 125955796-126063335 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 58.3;Fibroblasts: 23.5;Inhibitory neurons: 49.5;Muller glia cells: 39.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 23.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 28.4;ASC diff: 32.7;RH-30: 48.9;SuSa: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB012422, HPA017377" Uncertain NA NA 15000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB012422: AB_2260246, HPA017377: AB_1846453" "prognostic favorable (1.35e-4)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" "unprognostic (1.25e-4)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (2.49e-3)" "unprognostic (5.77e-3)" "unprognostic (2.78e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (5.39e-2)" "unprognostic (1.51e-1)" "unprognostic (5.83e-3)" "unprognostic (1.86e-4)" 12.6 0.7 1.9 1.6 2.0 0.0 5.1 23.0 4.0 7.9 1.2 12.4 1.0 14.0 2.1 1.7 14.2 4.8 4.0 1.6 1.8 0.8 1.2 2.7 1.1 2.2 1.9 20.6 1.2 2.5 3.0 2.7 2.7 1.3 1.6 10.1 1.7 2.8 1.2 9.9 2.9 17.0 0.5 0.7 4.6 3.6 2.3 2.8 18.5 1.6 1.5 2.5 3.0 2.1 1.6 3.2 28.4 2.8 32.7 14.5 0.4 0.5 2.9 0.9 0.3 1.1 9.4 1.4 6.8 0.6 3.3 0.4 7.1 1.0 0.8 5.5 6.3 0.5 6.5 2.9 6.4 0.4 1.8 4.5 1.2 0.6 0.0 12.2 0.3 4.8 0.1 1.9 2.7 0.4 3.6 1.0 2.6 0.8 3.7 1.1 48.9 0.9 1.7 0.5 2.4 9.6 3.7 0.3 4.7 23.8 2.4 1.0 0.5 3.2 2.2 6.3 3.3 2.5 5.5 0.2 2.0 1.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.0 23.0 4.0 1.6 1.8 2.2 1.9 2.7 0.5 2.3 2.1 3.0 6.4 9.9 11.1 0.1 15.2 1.4 0.8 2.2 5.1 5.4 1.9 5.2 2.8 5.6 0.0 16.7 0.6 0.1 0.2 0.0 1.3 3.1 1.7 0.5 3.0 7.7 0.4 58.3 0.6 0.4 23.5 1.5 1.1 0.0 1.8 1.1 2.1 0.3 0.0 49.5 0.3 0.0 0.0 7.6 2.7 14.9 0.2 3.6 2.8 0.1 39.3 0.0 14.1 5.8 2.4 0.4 11.3 0.8 1.1 0.6 0.5 4.2 4.6 0.0 2.9 2.7 1.8 3.8 0.5 10.7 0.7 0.6 13.2 0.4 1.6 CDSN D6S586E ENSG00000204539 Corneodesmosin 6 31115087-31120446 "Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "skin 1: 696.5" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 2.6;Gastric mucus-secreting cells: 2.0;Glandular and luminal cells: 7.1;granulocytes: 4.5;Suprabasal keratinocytes: 5.3" "Group enriched" "Detected in some" 8 "head and neck cancer: 2.4;melanoma: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "A-431: 1.6" "Region enhanced" "Detected in some" "cerebral cortex: 1.5" "Not detected" "Not detected" "HPA044730, HPA054184" Enhanced "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA044730: AB_10964923, HPA054184: AB_2682409" "unprognostic (1.46e-1)" "unprognostic (6.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-1)" "unprognostic (3.44e-2)" "unprognostic (8.80e-2)" "unprognostic (8.13e-2)" "unprognostic (3.92e-4)" "unprognostic (3.92e-3)" "unprognostic (1.74e-4)" "unprognostic (6.34e-2)" "unprognostic (2.75e-1)" "unprognostic (2.22e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.1 0.0 0.1 3.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 696.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 6.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.9 0.4 2.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.0 7.1 4.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 1.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.2 CDT1 "DUP, RIS2" ENSG00000167513 "Chromatin licensing and DNA replication factor 1" Q9H211 16 88803789-88809258 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 38.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.4;Erythroid cells: 71.3;Extravillous trophoblasts: 92.0;Spermatogonia: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 149.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017224 Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA017224: AB_1846468" "unprognostic (1.33e-1)" "unprognostic (2.04e-2)" "unprognostic (7.32e-2)" "unprognostic (2.67e-1)" "unprognostic (4.34e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (3.44e-3)" "unprognostic (2.81e-2)" "unprognostic (4.59e-2)" "unprognostic (1.21e-1)" "unprognostic (9.34e-2)" "prognostic unfavorable (2.69e-6)" "unprognostic (7.72e-3)" "unprognostic (5.79e-2)" "unprognostic (2.80e-2)" "unprognostic (8.54e-2)" 0.7 0.8 0.8 3.8 1.2 38.5 0.7 2.5 1.3 1.7 0.0 3.3 4.1 0.5 0.2 6.7 0.5 0.2 0.5 0.8 2.3 0.7 1.0 1.3 4.8 2.2 1.1 0.4 0.6 1.3 2.1 2.8 1.9 0.7 1.6 0.4 1.1 0.2 0.1 3.6 3.9 0.6 0.7 3.1 2.4 3.5 1.1 8.7 0.6 0.0 3.3 0.5 2.3 1.0 33.6 34.5 16.5 25.3 0.7 3.4 64.2 24.1 6.6 19.4 12.0 79.3 33.8 51.4 24.2 5.5 12.7 46.0 21.6 17.7 6.2 18.2 92.1 51.8 28.8 59.9 0.3 28.8 21.5 1.8 1.4 19.8 4.4 1.6 5.9 60.9 80.8 18.4 7.6 90.6 109.3 149.4 41.8 12.2 31.6 120.3 22.9 42.4 4.3 23.8 36.6 26.2 44.4 13.1 16.9 7.4 39.0 55.9 5.9 24.6 42.6 37.2 35.4 61.4 55.7 73.6 19.3 71.9 31.6 0.2 0.1 0.9 0.3 0.0 0.0 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.7 0.4 0.1 0.1 0.7 0.2 0.8 1.2 2.5 1.3 0.8 2.3 2.2 1.1 1.9 0.7 1.1 1.0 0.4 0.0 1.1 0.7 4.9 11.2 4.3 1.4 7.4 0.7 5.4 7.5 2.2 1.5 1.7 1.8 0.0 51.4 2.2 12.7 1.9 1.1 0.4 1.4 1.4 2.2 2.4 71.3 0.2 0.0 92.0 5.2 9.2 2.2 0.0 29.0 0.4 1.0 19.5 0.0 0.8 16.1 4.1 5.6 5.5 1.2 0.3 2.8 1.8 0.0 1.9 1.5 4.1 0.0 0.6 0.6 2.3 0.4 23.1 2.2 2.0 1.6 2.1 1.9 0.0 2.1 3.4 6.6 37.1 10.8 7.1 24.8 5.4 5.7 30.1 4.4 CENPE "KIF10, PPP1R61" ENSG00000138778 "Centromere protein E" Q02224 4 103105349-103198445 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein, Motor protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.0;lymphoid tissue: 9.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 75.1;Extravillous trophoblasts: 28.4;Granulosa cells: 32.0;Spermatocytes: 75.3;Spermatogonia: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011110, HPA042294" Enhanced Enhanced "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA011110: , HPA042294: AB_10797386" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "unprognostic (5.64e-3)" "unprognostic (2.55e-2)" "unprognostic (1.65e-1)" "unprognostic (3.44e-2)" "unprognostic (2.40e-8)" "unprognostic (2.49e-3)" "unprognostic (1.59e-2)" "unprognostic (3.38e-1)" "unprognostic (4.88e-5)" "unprognostic (1.15e-2)" "unprognostic (0.00e+0)" "unprognostic (9.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.05e-1)" "unprognostic (2.37e-1)" 0.4 0.2 0.4 2.7 0.4 10.0 0.6 0.3 0.5 0.4 0.4 1.8 1.5 0.6 0.0 2.0 0.2 0.8 0.2 0.3 0.6 0.2 0.5 0.8 5.6 0.5 0.5 0.1 0.1 0.3 0.0 1.4 0.9 0.3 2.0 0.4 0.3 0.2 0.0 2.0 1.7 1.1 0.3 1.2 1.1 4.1 0.5 9.2 0.2 0.6 4.9 0.8 0.6 0.5 42.6 11.8 42.2 20.5 2.7 6.2 8.4 36.7 18.2 26.9 17.9 19.6 22.2 28.6 9.2 13.7 19.2 18.2 30.3 15.1 42.2 35.9 11.3 33.5 26.8 13.6 0.4 39.9 18.6 1.8 1.1 21.7 18.0 6.0 22.9 25.2 34.4 32.5 34.8 15.6 31.5 18.9 13.8 17.0 17.9 20.9 38.5 9.3 8.0 8.4 19.3 11.5 32.9 22.9 9.0 16.0 12.9 13.9 26.1 25.8 27.2 27.2 38.6 15.9 28.6 28.8 14.2 21.7 27.8 2.9 0.0 0.3 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.5 0.2 0.6 0.0 0.4 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.9 0.3 0.5 0.5 1.4 3.2 2.2 1.0 6.6 3.6 1.5 2.9 0.0 7.6 1.8 2.7 1.9 0.0 1.3 0.0 8.4 12.7 3.9 4.7 0.0 0.5 7.7 3.5 5.7 4.2 1.2 75.1 2.0 0.0 28.4 6.5 4.6 6.9 7.0 32.0 4.2 0.9 14.1 0.0 1.9 4.3 4.1 10.4 5.7 3.5 0.9 9.6 0.0 0.0 6.0 1.3 2.1 0.5 3.1 1.8 1.4 2.6 16.0 1.4 0.8 0.3 0.3 2.6 0.0 5.7 7.4 75.3 51.0 8.3 2.8 3.6 6.6 7.0 11.6 1.9 CENPF hcp-1 ENSG00000117724 "Centromere protein F" P49454 1 214603195-214664571 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, DNA synthesis, Mitosis, Myogenesis" "Developmental protein" "Cancer-related genes, Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.8;lymphoid tissue: 33.0" "Cell type enhanced" "Detected in many" "Early spermatids: 84.4;Erythroid cells: 268.7;Extravillous trophoblasts: 78.8;Granulosa cells: 165.8;Spermatocytes: 107.5;Spermatogonia: 107.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA052382, HPA064308, CAB070134" Enhanced Supported Nucleoplasm Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB070134: AB_2229328, HPA052382: AB_2681808, HPA064308: AB_2732711" "unprognostic (2.80e-1)" "unprognostic (2.16e-1)" "unprognostic (2.65e-1)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (2.29e-5)" "unprognostic (1.13e-2)" "unprognostic (2.58e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.58e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.92e-2)" "unprognostic (1.71e-1)" "unprognostic (1.89e-2)" "unprognostic (4.12e-1)" 0.8 1.1 0.1 4.4 0.1 28.8 1.8 0.0 0.3 1.3 0.5 5.8 6.1 1.8 0.1 8.6 0.6 0.7 0.4 0.3 0.0 0.4 0.9 0.9 8.5 0.3 0.5 0.7 0.3 0.2 0.1 3.1 0.3 0.5 5.7 1.0 1.4 0.1 0.2 6.2 4.3 2.5 0.2 2.4 2.6 10.5 0.5 33.0 0.4 0.6 10.0 1.4 2.6 0.3 123.7 68.4 144.3 75.8 5.4 7.2 56.3 74.6 30.3 43.9 42.8 54.6 74.1 116.3 43.1 41.7 39.8 74.7 89.9 49.2 74.1 102.6 56.6 96.0 111.4 78.6 0.8 137.0 50.5 2.7 3.8 63.3 72.3 12.7 46.9 52.6 88.4 68.0 79.4 47.0 81.5 54.3 127.9 36.8 30.0 85.7 203.7 38.6 43.2 30.3 67.4 91.2 100.7 66.2 38.9 76.2 79.1 51.9 61.7 78.9 92.2 66.2 155.9 51.6 60.7 108.7 34.4 96.7 71.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.3 0.5 0.3 0.2 0.5 0.3 3.0 0.0 3.1 0.0 11.5 9.3 2.8 11.2 3.4 4.7 10.0 6.7 1.9 1.5 9.9 0.0 0.0 53.3 10.8 19.1 0.0 2.0 84.4 30.1 19.3 12.4 0.0 268.7 1.3 0.4 78.8 19.0 32.1 25.2 1.3 165.8 8.9 2.6 32.2 1.7 0.8 20.1 14.2 16.6 6.6 19.8 1.2 16.2 1.8 1.0 0.7 1.4 5.2 0.0 0.1 0.5 1.1 3.0 25.9 2.3 2.1 0.1 16.7 3.1 0.0 8.3 23.9 107.5 107.1 44.6 5.5 5.1 23.3 11.7 41.3 3.7 CENPJ "BM032, CPAP, LAP, LIP1, MCPH6, Sas-4, SASS4, SCKL4" ENSG00000151849 "Centromere protein J" Q9HC77 13 24882279-24922889 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Dwarfism, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.3" "Cell type enhanced" "Detected in many" "Early spermatids: 135.8;Spermatocytes: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 34.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076638 Supported Centrosome NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 29: Early spermatids - Spermatogenesis" Centrosome "HPA076638: " "unprognostic (2.69e-1)" "unprognostic (3.17e-1)" "unprognostic (2.68e-1)" "unprognostic (1.01e-2)" "unprognostic (9.39e-2)" "unprognostic (1.17e-2)" "unprognostic (2.15e-5)" "unprognostic (7.41e-2)" "unprognostic (1.50e-2)" "unprognostic (9.83e-2)" "unprognostic (2.44e-1)" "unprognostic (3.48e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (7.36e-2)" "unprognostic (5.51e-2)" "unprognostic (2.15e-1)" "unprognostic (1.13e-1)" 2.6 1.3 1.3 2.4 1.7 4.4 3.3 4.2 3.3 3.7 0.2 3.5 4.2 4.1 2.3 2.2 3.5 1.6 1.6 1.4 1.2 1.2 1.5 2.4 5.0 1.5 1.3 3.5 1.1 0.9 0.7 3.7 1.7 2.4 4.3 1.8 1.5 1.7 2.2 5.0 3.6 3.9 1.0 2.5 2.1 16.3 1.6 3.5 11.0 1.6 4.1 3.3 2.4 1.6 4.5 3.9 14.9 16.4 2.4 3.5 9.0 11.5 5.5 5.5 5.1 8.0 8.3 8.9 3.5 3.1 4.4 12.9 11.4 6.8 11.2 7.9 7.2 34.0 13.1 6.7 0.9 15.3 10.2 1.0 2.5 5.1 4.1 3.1 5.9 7.3 8.3 13.5 8.8 7.7 8.4 23.8 10.2 13.3 5.9 11.3 10.0 4.4 3.1 7.6 8.5 7.5 5.3 6.9 4.8 12.1 2.9 9.4 4.3 8.8 5.6 12.9 7.2 4.9 8.3 8.4 4.3 11.6 10.8 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 1.3 1.7 4.2 3.3 1.4 1.2 1.5 1.3 1.7 1.0 1.6 1.6 7.5 3.2 10.5 6.2 6.7 2.0 4.3 5.8 5.7 8.0 3.8 5.2 6.9 1.5 9.1 3.7 4.2 8.5 7.0 10.8 0.0 2.6 135.8 7.0 13.6 6.3 0.0 17.9 20.1 2.9 14.9 8.4 2.6 13.2 5.1 21.3 2.2 1.4 4.3 3.3 18.4 3.7 2.0 1.6 3.5 24.7 6.5 5.9 0.0 8.4 6.6 3.4 4.1 16.6 13.8 1.9 6.9 5.7 12.6 2.3 8.2 1.1 6.1 2.3 6.6 8.6 10.3 63.5 36.3 5.4 1.3 2.9 6.1 5.2 5.6 2.3 CENPT "C16orf56, CENP-T, FLJ13111" ENSG00000102901 "Centromere protein T" Q96BT3 16 67828157-67847811 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Spermatocytes: 89.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041220, HPA058036" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear bodies" Nucleoplasm "HPA041220: AB_2677367, HPA058036: AB_2683585" "unprognostic (9.84e-2)" "unprognostic (2.86e-2)" "unprognostic (3.04e-2)" "unprognostic (8.77e-2)" "unprognostic (3.14e-2)" "unprognostic (6.66e-3)" "unprognostic (1.18e-2)" "unprognostic (2.81e-1)" "unprognostic (8.04e-2)" "unprognostic (3.15e-2)" "prognostic favorable (2.96e-4)" "unprognostic (6.64e-3)" "prognostic unfavorable (1.57e-7)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (9.23e-2)" "unprognostic (9.74e-3)" 7.0 5.6 7.2 3.1 7.1 5.3 6.4 7.4 10.0 7.9 5.7 8.1 2.4 7.0 1.4 6.6 7.3 1.8 8.0 7.4 7.8 6.3 5.3 6.3 3.6 7.5 7.3 7.7 9.6 4.9 4.3 4.2 7.6 6.5 2.0 0.8 5.8 4.3 8.2 24.8 6.3 4.7 6.8 5.5 7.4 19.6 7.3 4.4 5.1 5.6 2.3 7.3 6.9 7.2 7.6 7.4 10.0 10.2 8.1 7.8 14.7 29.5 13.6 30.2 24.1 7.9 5.6 3.3 7.1 19.8 5.3 12.4 7.5 13.2 10.3 5.3 9.5 1.2 3.2 11.3 5.1 0.6 6.9 8.5 7.7 20.7 4.4 4.4 12.3 8.1 19.3 3.6 14.5 11.9 9.8 10.7 13.5 5.9 7.1 13.4 4.5 17.6 11.2 3.1 3.9 6.8 22.2 4.6 5.8 6.3 6.1 10.0 9.7 4.3 7.4 6.6 7.0 7.0 5.8 19.4 3.3 6.1 7.4 1.4 7.2 6.3 6.5 6.6 7.0 4.9 6.0 8.2 6.0 6.1 5.3 7.0 3.4 5.4 4.3 6.0 8.5 5.1 7.2 7.1 7.4 10.0 7.4 7.8 7.5 7.3 7.6 6.8 7.3 7.2 21.0 16.0 11.3 10.4 17.4 21.0 20.2 24.4 12.5 24.9 20.3 19.3 8.2 14.3 17.2 20.2 8.4 31.5 25.4 27.5 5.9 19.0 52.2 8.8 17.8 19.7 13.1 30.3 16.9 14.2 25.0 23.0 34.1 11.2 8.2 20.9 17.5 9.4 15.2 25.2 12.3 11.3 24.4 8.5 17.8 47.9 24.2 17.9 17.8 7.5 9.8 13.7 21.6 12.1 8.4 19.7 17.8 22.2 26.9 11.1 16.3 10.3 12.2 10.5 26.3 19.9 25.1 89.8 33.5 12.8 19.5 30.1 22.6 24.3 13.7 13.6 CEP104 "CFAP256, GlyBP, JBTS25, KIAA0562, ROC22, RP1-286D6.4" ENSG00000116198 "Centrosomal protein 104" O60308 1 3812086-3857396 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Cone photoreceptor cells: 458.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010126 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA010126: AB_10601583" "unprognostic (3.60e-2)" "unprognostic (1.39e-1)" "unprognostic (8.83e-2)" "unprognostic (2.00e-2)" "unprognostic (1.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.49e-3)" "unprognostic (8.35e-2)" "unprognostic (4.85e-1)" "unprognostic (2.16e-1)" "unprognostic (4.90e-1)" "unprognostic (2.89e-1)" "prognostic favorable (1.70e-5)" "unprognostic (7.06e-3)" "unprognostic (2.62e-1)" "unprognostic (1.46e-1)" "unprognostic (3.55e-1)" 9.0 9.1 7.0 6.6 11.6 3.1 6.4 9.3 7.7 6.9 12.0 8.1 5.2 7.1 4.3 7.6 7.9 6.2 7.6 5.4 7.9 11.3 8.7 7.5 7.1 10.1 11.4 7.5 8.8 14.0 8.1 6.6 10.2 7.7 6.6 9.0 7.8 8.6 9.5 7.1 7.1 9.3 7.7 6.6 7.6 9.6 10.1 8.4 9.9 6.9 8.7 8.1 6.7 9.1 13.4 10.8 8.8 11.8 20.9 15.9 6.8 14.0 11.2 19.5 12.8 8.0 11.4 15.7 17.6 14.8 14.0 12.8 20.3 13.1 23.1 22.1 15.5 15.8 12.7 10.2 13.5 15.5 13.3 8.0 13.0 17.9 28.0 13.6 16.6 17.3 19.6 15.7 18.3 6.2 22.8 6.3 6.3 18.9 20.2 14.1 12.3 17.1 12.7 7.8 22.1 8.8 21.7 23.8 15.0 10.8 10.2 8.0 19.1 14.0 6.5 23.6 11.4 13.0 20.6 22.5 7.9 17.4 5.6 0.3 0.1 1.5 0.6 0.2 0.5 0.2 0.4 0.6 0.3 0.7 0.7 0.1 0.2 0.7 0.4 0.9 0.2 0.1 7.0 11.6 9.3 7.7 5.4 7.9 10.1 11.4 10.2 7.7 10.1 9.1 13.7 25.6 25.9 15.7 14.7 15.9 14.2 9.2 12.0 24.8 12.8 9.1 14.1 12.8 13.9 25.8 458.7 16.3 18.6 16.2 7.9 26.0 74.9 34.3 14.4 15.4 11.3 10.7 23.7 19.6 24.4 12.9 12.2 18.9 10.8 12.6 8.9 18.4 13.2 58.9 24.6 13.5 4.1 14.6 7.8 91.7 12.5 14.3 19.6 12.2 21.0 13.8 22.6 12.1 34.1 24.3 11.7 20.7 23.2 19.2 16.6 18.5 28.7 55.2 19.7 19.8 16.1 63.7 23.5 15.0 20.0 11.4 17.2 18.2 12.7 13.7 CEP120 "CCDC100, FLJ36090" ENSG00000168944 "Centrosomal protein 120" Q8N960 5 123344890-123423592 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028823, HPA051556" Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" "HPA028823: AB_10601355, HPA051556: AB_2681533" "unprognostic (3.65e-1)" "unprognostic (9.94e-2)" "unprognostic (3.69e-2)" "unprognostic (1.49e-1)" "unprognostic (1.10e-1)" "unprognostic (2.97e-2)" "unprognostic (4.41e-1)" "unprognostic (1.15e-1)" "unprognostic (2.83e-2)" "unprognostic (5.74e-2)" "unprognostic (1.82e-2)" "unprognostic (1.51e-1)" "unprognostic (4.94e-3)" "unprognostic (1.05e-1)" "unprognostic (1.69e-1)" "unprognostic (9.44e-3)" "unprognostic (1.58e-1)" 8.3 7.1 1.6 7.1 1.9 3.0 7.2 2.0 2.6 8.8 2.1 7.2 4.9 9.3 3.6 4.5 9.4 7.2 6.2 2.1 2.1 7.0 7.9 7.3 9.6 2.0 2.1 15.5 6.3 7.6 6.5 6.0 1.9 6.9 5.1 11.6 5.2 7.7 4.4 4.1 7.3 8.0 1.7 9.1 5.1 13.8 1.9 14.1 8.2 6.2 10.9 6.7 6.1 2.3 8.5 7.7 10.6 12.7 11.9 13.7 9.1 11.4 14.1 10.8 19.3 5.7 7.2 11.9 9.7 6.7 17.6 5.3 9.2 10.0 18.5 27.1 4.1 6.2 2.7 6.9 12.8 7.0 11.1 11.5 12.3 14.8 19.3 9.2 9.7 9.8 6.0 20.5 12.6 3.0 13.3 2.8 5.8 3.8 7.1 7.2 15.5 8.9 5.8 2.9 11.3 8.1 9.1 4.0 13.8 12.4 5.8 16.3 8.3 11.7 9.5 5.8 13.7 12.4 11.5 8.3 10.8 14.2 12.3 0.8 0.2 0.6 0.4 0.4 0.5 0.7 1.0 0.7 0.3 0.3 0.6 1.0 0.1 0.3 0.1 0.0 1.7 0.4 1.6 1.9 2.0 2.6 2.1 2.1 2.0 2.1 1.9 1.7 1.9 2.3 15.1 12.8 10.3 8.8 24.5 5.9 4.1 5.0 15.4 10.2 6.3 4.8 10.0 1.5 10.3 7.3 29.2 4.3 12.4 4.2 1.9 2.8 9.4 12.4 7.8 10.8 2.4 7.2 22.8 4.7 4.3 10.8 9.7 5.7 2.5 20.9 4.6 7.2 5.6 8.4 28.2 3.9 4.1 12.0 4.3 6.4 11.8 9.9 8.8 29.0 9.4 7.6 7.2 19.1 24.2 4.2 3.1 13.9 19.1 3.1 7.1 3.3 26.2 17.4 6.6 10.3 8.9 17.4 9.9 6.3 1.8 2.3 23.0 8.2 3.9 3.2 CEP135 "CEP4, FLJ13621, KIAA0635" ENSG00000174799 "Centrosomal protein 135" Q66GS9 4 55948871-56033361 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 92.3;monocytes: 64.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.75e-1)" "unprognostic (2.71e-2)" "unprognostic (2.48e-2)" "unprognostic (1.06e-2)" "unprognostic (3.63e-1)" "unprognostic (3.42e-2)" "unprognostic (4.65e-3)" "unprognostic (4.78e-3)" "unprognostic (1.83e-3)" "unprognostic (9.89e-3)" "unprognostic (9.50e-2)" "unprognostic (2.27e-1)" "unprognostic (6.02e-9)" "unprognostic (7.55e-2)" "unprognostic (5.54e-2)" "unprognostic (1.95e-1)" "prognostic favorable (6.11e-5)" 2.6 1.6 1.0 7.2 1.3 10.1 2.8 2.1 1.6 3.5 1.9 2.4 3.1 7.6 2.1 2.0 3.3 3.1 1.4 1.2 1.3 4.0 1.3 3.2 10.2 1.7 1.5 5.0 1.7 2.0 1.2 5.9 1.7 2.3 3.2 3.7 1.5 1.6 0.8 3.9 3.3 5.0 1.0 5.7 2.2 6.4 2.0 9.5 2.6 1.3 7.6 2.9 2.2 1.9 8.9 4.8 13.0 12.3 2.6 5.0 5.5 8.6 6.1 7.7 9.0 5.2 9.0 23.7 6.4 3.8 6.0 4.0 13.8 5.2 14.6 6.5 8.4 8.3 7.6 4.9 2.9 15.2 12.6 3.9 4.1 9.9 7.0 3.4 6.5 11.9 15.4 11.0 8.1 5.2 21.3 9.5 8.3 4.4 4.9 15.4 6.1 4.8 5.6 6.4 9.3 9.6 7.7 5.2 6.4 7.8 6.9 9.7 6.5 10.4 17.0 12.5 15.1 5.9 4.4 15.7 5.2 11.8 13.1 9.9 2.1 2.9 3.0 2.8 2.8 3.0 3.9 2.9 1.5 5.6 5.0 3.1 4.3 4.7 3.2 5.6 2.7 1.4 1.0 1.3 2.1 1.6 1.2 1.3 1.7 1.5 1.7 1.0 2.0 1.9 16.3 6.4 12.4 7.8 30.2 9.1 8.2 6.3 7.4 12.6 5.6 6.6 8.5 2.8 9.4 7.3 10.4 20.0 27.3 5.2 3.9 9.4 92.3 23.1 14.6 18.2 5.4 28.2 10.0 5.4 16.3 11.5 3.1 13.0 14.5 38.2 12.5 1.7 10.4 26.9 10.4 5.5 6.1 12.9 11.3 19.4 5.9 19.2 5.4 19.7 64.5 4.3 32.0 8.0 13.9 15.6 6.7 8.2 16.7 5.2 3.0 10.0 17.4 24.5 6.6 16.2 11.2 57.3 38.7 6.8 6.7 9.6 20.0 34.6 5.7 6.3 CEP152 "KIAA0912, MCPH9, SCKL5" ENSG00000103995 "Centrosomal protein 152" O94986 15 48712928-48811146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant, Dwarfism, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3" "Cell type enhanced" "Detected in many" "Early spermatids: 192.5;Late spermatids: 49.5;Syncytiotrophoblasts: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039408 Approved Supported Nucleoplasm,Centrosome NA Yes "Cluster 42: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Centrosome Nucleoplasm "HPA039408: AB_10795288" "unprognostic (3.64e-1)" "unprognostic (1.91e-1)" "unprognostic (2.61e-1)" "unprognostic (4.08e-2)" "unprognostic (2.09e-1)" "unprognostic (3.87e-4)" "unprognostic (4.78e-2)" "unprognostic (8.02e-3)" "unprognostic (1.04e-2)" "unprognostic (5.82e-2)" "unprognostic (4.70e-3)" "unprognostic (3.47e-2)" "unprognostic (6.24e-3)" "unprognostic (5.29e-2)" "unprognostic (3.55e-1)" "unprognostic (4.60e-2)" "unprognostic (1.25e-1)" 2.2 1.3 1.2 3.5 1.4 16.3 1.9 2.0 1.9 1.9 2.6 2.3 2.9 1.4 0.9 2.6 1.9 1.8 2.1 1.0 0.9 2.2 1.0 2.2 4.3 1.2 1.2 2.5 2.9 1.3 0.9 4.7 1.4 1.7 3.1 1.9 2.4 0.9 1.0 3.0 2.9 1.9 0.7 2.4 2.3 9.8 1.8 5.6 2.9 0.6 3.7 1.4 2.3 1.8 8.0 6.1 12.2 15.0 2.1 3.9 7.9 13.9 5.6 10.0 12.3 13.2 6.8 18.6 5.9 4.0 14.1 18.6 13.6 5.0 14.5 16.5 8.3 30.1 34.6 7.2 1.4 25.6 13.4 1.4 3.9 11.1 6.6 3.9 7.5 19.2 18.4 21.6 8.6 4.5 18.6 23.8 7.7 9.5 6.1 22.7 16.4 22.9 3.6 7.5 14.6 9.8 10.7 8.9 4.2 13.3 6.7 12.3 6.2 24.4 12.9 18.9 15.6 9.2 10.8 21.4 7.8 36.2 17.6 2.1 1.0 1.9 0.8 1.4 0.7 0.9 0.9 0.9 0.8 1.7 1.0 1.0 1.8 1.2 1.5 1.5 1.0 0.5 1.2 1.4 2.0 1.9 1.0 0.9 1.2 1.2 1.4 0.7 1.8 1.8 3.9 6.4 2.8 22.2 9.3 3.8 4.1 2.8 4.0 1.5 2.9 3.6 3.9 4.3 1.8 3.7 2.1 31.5 6.8 7.8 0.0 4.7 192.5 6.4 5.3 6.7 3.6 29.9 14.7 6.7 8.5 9.0 7.1 5.0 8.2 20.9 6.1 3.3 7.6 0.0 8.4 8.2 4.1 7.2 6.4 49.5 23.9 8.6 1.8 16.9 6.9 2.9 10.3 6.0 7.0 7.9 3.5 27.1 15.9 3.2 9.1 1.7 8.4 3.6 6.6 6.5 5.4 24.4 10.3 7.0 3.4 46.9 9.9 3.4 10.1 4.1 CEP164 "KIAA1052, NPHP15" ENSG00000110274 "Centrosomal protein 164" Q9UPV0 11 117314557-117413266 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, DNA damage, DNA repair, Mitosis" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 454.5;Early spermatids: 241.0;Late spermatids: 291.7;Rod photoreceptor cells: 268.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037605, HPA037606" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Centrosome" "HPA037605: AB_10672908, HPA037606: AB_10672498" "unprognostic (1.92e-1)" "unprognostic (8.99e-2)" "unprognostic (7.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.47e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.82e-1)" "unprognostic (3.14e-2)" "unprognostic (1.90e-1)" "prognostic favorable (5.93e-4)" "unprognostic (6.54e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "unprognostic (2.13e-1)" "unprognostic (7.93e-2)" 7.0 5.8 6.7 9.7 8.2 7.3 6.8 10.8 8.0 10.5 11.5 7.3 4.2 10.8 8.1 8.6 11.4 8.4 4.3 5.5 7.9 5.1 7.3 6.7 7.6 8.2 7.5 11.9 26.3 5.6 11.1 4.6 8.1 6.9 5.1 26.0 5.7 5.8 3.1 8.0 6.2 10.3 4.9 8.5 5.8 23.9 9.2 7.7 8.4 1.3 8.5 7.1 7.5 14.0 13.2 18.0 13.0 25.9 12.8 21.7 4.2 25.6 14.3 18.0 17.5 22.4 20.8 25.9 18.1 15.9 17.7 17.1 14.6 15.0 15.3 25.8 12.0 7.8 18.9 7.1 18.9 11.3 16.8 15.2 12.6 27.3 26.5 16.1 23.6 12.6 21.7 16.4 14.4 11.2 10.6 10.2 9.2 8.5 19.4 14.0 15.5 10.1 7.9 11.3 15.1 21.8 20.3 12.2 14.4 14.4 16.9 13.2 25.7 21.3 13.2 20.7 23.8 5.8 7.7 15.2 10.3 12.6 14.5 96.2 34.3 23.4 35.4 30.9 22.9 38.8 44.3 40.4 13.9 41.0 41.4 32.6 82.5 29.6 42.0 49.4 52.6 10.8 6.7 8.2 10.8 8.0 5.5 7.9 8.2 7.5 8.1 4.9 9.2 14.0 21.0 6.4 13.1 28.1 15.4 7.6 10.3 13.2 10.8 97.7 14.5 23.6 5.8 15.7 10.3 11.0 454.5 4.5 14.3 9.0 1.9 11.1 241.0 26.5 30.3 18.3 15.5 8.0 19.0 14.7 6.8 17.2 17.9 14.7 19.6 17.6 13.2 9.0 12.9 74.0 26.3 10.2 10.2 11.7 11.4 291.7 23.9 14.5 5.4 8.4 21.2 23.4 15.5 21.6 28.7 11.7 5.8 17.0 11.0 9.8 5.4 6.2 31.6 268.7 0.0 30.3 21.4 37.6 17.2 11.4 8.1 2.2 16.4 45.0 11.9 5.6 CEP290 "3H11Ag, BBS14, CT87, FLJ13615, JBTS5, KIAA0373, LCA10, MKS4, NPHP6, POC3, rd16, SLSN6" ENSG00000198707 "Centrosomal protein 290" O15078 12 88049016-88142099 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" Activator "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Joubert syndrome, Leber congenital amaurosis, Meckel syndrome, Mental retardation, Nephronophthisis, Obesity, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 150.5;Spermatocytes: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB029995, HPA043918, HPA064397" Approved Supported Centrosome NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 46: Photoreceptor cells - Phototransduction" Centrosome "CAB029995: , HPA043918: AB_2678730, HPA064397: AB_2685255" "unprognostic (7.42e-2)" "unprognostic (4.02e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "unprognostic (3.26e-1)" "unprognostic (8.90e-2)" "unprognostic (1.45e-4)" "unprognostic (2.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (2.94e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (3.21e-6)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (2.44e-2)" "unprognostic (3.84e-3)" 5.2 5.1 2.7 4.0 3.4 2.8 5.0 3.1 3.8 7.9 1.9 6.3 1.5 6.4 2.7 2.4 8.0 2.6 4.5 2.8 2.9 7.1 3.6 5.0 3.6 2.8 3.0 12.3 4.6 9.0 8.4 3.3 3.0 6.8 2.6 7.2 3.5 2.1 2.9 3.7 4.6 2.9 2.7 4.5 4.8 8.6 2.9 4.3 7.3 1.2 2.6 6.0 4.9 4.3 8.3 4.9 9.8 2.0 4.2 16.1 3.8 8.2 6.6 5.8 5.0 7.3 3.3 7.6 3.6 6.1 9.1 6.4 2.7 5.2 9.1 4.2 4.7 7.5 4.5 4.7 7.6 10.0 3.4 8.3 3.3 12.5 10.4 11.3 11.3 6.5 15.4 1.4 11.0 3.8 5.7 6.2 2.5 1.3 8.5 4.5 11.6 5.1 4.9 6.1 4.7 8.3 5.0 2.5 6.4 7.6 11.3 3.3 10.0 9.5 5.5 8.1 10.7 6.0 10.4 8.2 3.5 3.7 3.9 0.0 0.0 0.1 0.6 0.1 0.8 0.2 0.7 0.5 0.0 0.3 0.7 0.5 0.0 0.5 0.2 0.6 0.5 0.0 2.7 3.4 3.1 3.8 2.8 2.9 2.8 3.0 3.0 2.7 2.9 4.3 29.0 86.6 32.1 56.2 22.5 6.4 16.9 17.5 17.1 65.9 15.1 16.5 50.0 25.8 35.2 29.5 102.2 13.0 28.6 8.4 7.9 26.0 70.6 89.0 57.0 24.6 4.9 12.4 91.8 13.1 8.8 26.1 14.3 32.1 19.0 56.2 13.9 5.7 13.9 65.6 93.7 17.4 34.6 6.3 7.4 29.4 28.6 13.5 14.2 30.9 11.4 35.0 33.0 67.3 100.4 19.0 6.5 37.6 22.5 9.2 6.9 11.0 81.8 150.5 32.9 42.5 32.2 143.9 53.5 6.4 5.5 5.6 23.7 46.1 15.8 9.4 CEP41 "DKFZp762H1311, FLJ22445, JBTS15, TSGA14" ENSG00000106477 "Centrosomal protein 41" Q9BYV8 7 130393771-130442433 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Autism, Autism spectrum disorder, Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.0" "Cell type enhanced" "Detected in all" "Early spermatids: 526.8;Late spermatids: 160.6;Spermatocytes: 96.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024090 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA024090: AB_10966276" "unprognostic (3.87e-2)" "unprognostic (5.96e-2)" "prognostic favorable (4.54e-4)" "unprognostic (1.17e-3)" "unprognostic (2.88e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-7)" "unprognostic (1.80e-1)" "unprognostic (2.89e-1)" "unprognostic (8.45e-3)" "unprognostic (4.63e-2)" "unprognostic (1.37e-1)" "unprognostic (7.76e-2)" "unprognostic (7.72e-2)" "unprognostic (3.35e-2)" "unprognostic (9.87e-2)" "unprognostic (1.57e-1)" 3.8 5.2 4.9 3.5 5.0 4.2 3.6 3.6 5.6 3.5 8.8 3.0 3.2 4.3 3.7 2.6 9.4 4.6 2.0 5.3 5.2 3.3 2.7 3.2 4.7 4.8 8.1 3.5 2.2 5.1 4.7 4.5 5.2 3.2 3.6 7.7 17.8 3.6 1.6 2.4 2.2 5.3 4.7 4.2 2.8 47.0 5.3 8.6 4.1 2.3 4.9 3.2 1.4 6.4 15.9 16.5 17.6 11.4 5.1 8.9 3.6 21.0 10.4 12.4 13.9 9.8 19.3 23.1 11.3 12.3 34.4 15.2 17.6 11.3 17.2 8.0 5.0 8.4 7.2 5.2 8.5 16.7 8.0 9.7 8.6 16.2 7.2 12.0 21.9 16.7 4.8 5.3 21.5 10.7 43.2 14.7 15.7 17.4 12.6 30.3 25.7 0.7 9.1 10.3 25.4 21.0 14.0 19.9 16.3 9.9 6.1 12.8 11.0 18.4 7.2 17.6 27.3 12.2 39.9 28.8 20.7 16.4 27.8 7.9 4.6 5.9 7.5 6.9 4.9 3.6 5.4 5.7 8.3 4.5 8.4 13.9 0.8 11.2 3.3 4.0 6.3 7.4 4.9 5.0 3.6 5.6 5.3 5.2 4.8 8.1 5.2 4.7 5.3 6.4 8.7 9.6 4.1 7.2 5.0 1.8 6.4 13.5 4.6 18.1 11.6 9.0 4.4 4.3 10.1 9.2 37.5 16.2 3.8 3.1 11.7 12.9 526.8 35.9 8.9 9.6 14.4 12.4 14.5 9.2 10.9 7.8 4.6 5.3 11.4 13.3 12.8 3.4 18.7 15.2 12.5 4.7 10.2 8.9 2.2 160.6 10.5 8.0 5.4 5.6 4.0 10.2 9.2 17.1 14.2 7.0 3.7 8.2 1.9 4.0 2.0 5.2 55.5 22.0 6.6 6.3 7.4 96.0 35.0 4.1 1.6 19.2 5.8 8.7 6.3 6.5 CEP55 "C10orf3, CT111, FLJ10540" ENSG00000138180 "Centrosomal protein 55" Q53EZ4 10 93496612-93529092 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4;testis: 21.7" "Cell type enhanced" "Detected in many" "Early spermatids: 29.4;Extravillous trophoblasts: 17.1;Granulosa cells: 19.8;Spermatocytes: 77.3;Spermatogonia: 17.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "T-reg: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA023430 Approved Approved "Plasma membrane,Midbody,Centriolar satellite" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centriolar satellite" Midbody "HPA023430: AB_10960212" "unprognostic (9.85e-2)" "unprognostic (1.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (3.20e-9)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.66e-5)" "unprognostic (3.99e-2)" "prognostic unfavorable (0.00e+0)" "prognostic favorable (3.15e-4)" "unprognostic (7.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" 1.3 0.6 0.0 7.6 0.0 5.0 1.4 0.0 0.2 1.7 0.0 7.0 6.7 1.4 0.1 7.3 0.4 1.4 0.3 0.0 0.1 0.3 0.6 1.3 14.7 0.1 0.3 0.2 0.2 0.2 0.3 3.5 0.2 0.3 8.8 0.0 1.2 0.3 0.1 4.5 6.3 5.2 0.0 2.4 4.6 21.7 0.4 27.4 0.5 0.2 15.5 3.1 2.3 0.1 208.5 81.5 53.0 67.7 5.8 12.0 29.6 112.4 78.2 103.5 106.4 87.2 108.6 55.4 48.2 72.8 69.6 115.4 64.8 54.8 123.4 167.2 33.7 21.0 49.2 29.9 0.6 36.3 46.3 2.8 3.8 110.6 133.5 30.7 97.1 89.9 19.3 101.8 118.5 48.3 96.3 54.8 20.9 64.2 58.8 41.3 86.9 30.3 47.1 25.5 21.7 30.7 86.3 26.3 64.9 40.1 68.9 36.4 61.4 65.3 90.6 90.5 186.7 45.1 66.1 66.8 51.0 134.8 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.1 0.2 0.0 1.3 0.0 2.7 3.6 0.9 1.9 0.0 0.0 1.8 2.0 0.4 2.8 0.2 0.0 0.0 7.7 0.9 3.3 0.0 0.6 29.4 1.7 2.0 1.5 0.0 2.5 0.5 0.2 17.1 2.3 8.2 3.6 0.0 19.8 2.2 0.3 12.9 0.0 0.3 4.5 4.1 7.0 5.1 8.2 0.3 5.1 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 0.4 14.8 1.1 0.4 0.0 0.2 0.0 0.0 0.5 4.5 77.3 17.3 16.1 1.3 1.5 4.3 1.6 7.9 1.7 CEP63 FLJ13386 ENSG00000182923 "Centrosomal protein 63" Q96MT8 3 134485721-134575017 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Mitosis" "Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 139.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 179.4" "Lineage enriched" "Detected in all" 6 "granulocytes: 179.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058154, HPA058313" Approved Approved Nucleoplasm NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 23: Testis - Cell cycle regulation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA058154: AB_2683624, HPA058313: " "unprognostic (1.80e-1)" "unprognostic (1.03e-2)" "unprognostic (2.13e-1)" "unprognostic (1.38e-2)" "unprognostic (1.12e-1)" "unprognostic (2.08e-1)" "unprognostic (1.60e-2)" "unprognostic (2.23e-2)" "unprognostic (2.71e-2)" "unprognostic (1.32e-1)" "unprognostic (1.71e-1)" "unprognostic (3.08e-2)" "unprognostic (5.24e-2)" "unprognostic (5.75e-2)" "unprognostic (1.05e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" 23.9 15.2 7.4 14.0 9.8 30.2 16.1 10.0 13.7 13.1 6.8 16.4 10.0 12.9 16.9 12.4 12.2 11.3 25.1 7.5 10.9 16.4 21.9 11.8 18.5 9.4 9.1 16.2 17.0 18.8 12.7 14.4 9.7 14.5 14.3 22.0 16.0 15.9 41.5 14.8 11.2 16.4 7.7 16.2 14.7 45.2 9.3 27.5 18.9 29.0 17.4 15.7 12.5 11.7 32.9 12.6 26.2 17.5 36.9 30.7 24.6 35.1 29.1 26.7 21.9 11.8 13.7 36.5 21.0 24.4 26.0 18.6 14.5 18.0 32.3 41.7 7.4 47.9 15.0 16.1 25.3 30.5 22.0 26.4 23.3 14.8 47.1 28.8 27.9 48.2 14.7 31.3 32.4 20.1 37.7 34.5 18.4 20.1 16.9 23.5 38.7 52.8 23.7 20.3 14.8 14.6 31.2 12.1 47.3 30.2 24.7 38.1 30.1 30.1 18.4 30.3 26.9 27.1 21.9 46.7 33.4 30.8 39.2 72.7 20.1 34.3 12.7 20.6 16.9 15.9 12.2 16.5 24.6 22.2 17.2 13.1 179.4 20.3 29.5 16.3 16.8 12.7 7.4 9.8 10.0 13.7 7.5 10.9 9.4 9.1 9.7 7.7 9.3 11.7 19.9 19.2 27.6 39.2 25.5 10.7 14.6 22.6 13.6 31.6 16.8 22.5 84.7 22.8 23.1 7.3 20.9 25.3 16.5 11.8 31.3 25.8 93.2 21.8 23.6 21.0 13.1 26.5 63.5 20.0 26.0 25.8 14.8 17.9 52.6 25.2 14.6 17.3 29.4 32.0 58.3 16.0 16.2 27.7 12.8 54.9 23.9 25.1 17.8 28.1 30.2 26.3 19.6 71.4 67.8 21.0 16.2 25.9 27.3 19.2 12.5 29.6 31.1 43.8 19.7 31.7 25.1 139.1 51.7 17.3 9.8 17.4 20.6 18.8 16.2 16.2 CEP83 "CCDC41, NPHP18, NY-REN-58" ENSG00000173588 "Centrosomal protein 83" Q9Y592 12 94306449-94459988 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 109.1;Oligodendrocyte precursor cells: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038161 Approved NA NA "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA038161: AB_10674547" "unprognostic (4.98e-2)" "unprognostic (1.64e-2)" "unprognostic (7.22e-2)" "unprognostic (1.75e-2)" "unprognostic (4.76e-3)" "unprognostic (3.59e-2)" "unprognostic (5.44e-3)" "unprognostic (1.70e-1)" "unprognostic (2.24e-2)" "unprognostic (1.92e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.98e-4)" "prognostic unfavorable (5.00e-10)" "unprognostic (1.29e-2)" "unprognostic (7.83e-2)" "unprognostic (1.12e-2)" "unprognostic (1.95e-2)" 5.5 7.9 4.7 5.3 4.7 6.9 6.8 5.3 5.3 6.0 7.3 5.4 3.9 6.2 6.0 5.1 11.5 3.9 15.2 5.1 4.4 6.1 5.1 5.4 6.0 5.5 6.5 7.8 9.7 5.5 5.1 4.5 5.5 5.2 7.1 5.3 4.1 2.8 5.1 4.9 4.3 4.5 5.6 5.3 5.1 18.6 4.7 5.3 7.1 3.3 5.9 4.6 5.4 6.1 8.2 9.1 15.1 14.2 6.5 8.7 12.9 14.2 4.5 10.1 10.3 11.3 6.7 21.3 3.0 4.3 6.4 11.4 18.3 10.9 15.5 12.5 13.3 12.7 9.2 11.5 6.5 20.9 8.3 5.7 8.9 8.4 25.6 5.9 9.6 17.1 16.6 8.5 10.6 8.3 14.3 34.5 17.2 14.0 16.6 19.4 14.2 21.6 9.1 10.2 15.6 6.5 11.9 13.9 9.9 13.3 9.5 13.0 5.7 11.8 7.3 5.9 11.3 11.1 13.3 19.3 4.9 21.8 11.4 0.6 2.5 1.5 3.8 2.5 3.6 4.7 3.9 3.1 5.7 4.8 4.0 3.6 1.0 4.6 1.2 6.1 5.2 1.5 4.7 4.7 5.3 5.3 5.1 4.4 5.5 6.5 5.5 5.6 4.7 6.1 10.3 16.0 10.7 37.5 17.9 0.0 15.3 0.0 23.9 12.9 12.7 11.7 39.0 1.5 11.8 3.7 14.6 6.8 9.4 8.9 1.9 4.7 55.4 109.1 26.3 8.0 14.9 14.9 51.7 3.5 9.6 13.3 17.3 17.0 26.6 17.8 2.9 5.2 5.7 5.0 45.6 11.9 0.0 4.6 0.0 16.6 10.8 11.6 0.0 46.9 15.1 4.9 11.3 74.4 55.0 3.5 5.2 6.4 17.4 15.0 1.9 5.5 48.1 12.0 0.0 24.9 7.8 45.4 24.0 18.4 0.0 3.3 10.5 15.2 12.5 13.2 CERS3 "LASS3, MGC27091" ENSG00000154227 "Ceramide synthase 3" Q8IU89 15 100400395-100544995 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 55.1;skin 1: 64.0;vagina: 30.3" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 18.9;Basal squamous epithelial cells: 39.3;Early spermatids: 23.5;Late spermatids: 17.5;Spermatocytes: 28.2;Squamous epithelial cells: 48.3;Suprabasal keratinocytes: 50.2" "Cancer enhanced" "Detected in some" "head and neck cancer: 14.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTCEpi: 65.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006092, HPA024356" Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA006092: AB_1079236, HPA024356: AB_1852721" "unprognostic (5.01e-3)" "unprognostic (3.43e-2)" "unprognostic (6.47e-4)" "unprognostic (2.35e-2)" "unprognostic (5.58e-2)" "unprognostic (1.68e-1)" "unprognostic (6.84e-3)" "unprognostic (3.23e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-1)" "unprognostic (1.31e-5)" "unprognostic (2.65e-1)" "unprognostic (4.74e-4)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.78e-1)" "unprognostic (4.05e-3)" 0.1 0.0 0.1 0.0 0.2 0.2 3.3 0.3 0.2 15.1 0.0 0.0 0.0 0.0 0.5 55.1 0.7 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.6 0.0 0.1 8.4 0.1 0.6 64.0 0.1 0.0 0.0 0.1 0.1 18.3 0.2 0.4 0.1 0.0 16.0 0.3 30.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 1.3 0.0 18.9 5.0 3.9 39.3 0.4 0.1 0.3 0.5 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.5 0.2 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.1 17.5 0.6 0.1 0.0 0.0 0.0 0.2 0.0 2.0 1.4 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 28.2 0.7 48.3 50.2 0.0 0.1 0.0 0.0 6.0 CFAP410 "A2, C21orf2, LRRC76, YF5" ENSG00000160226 "Cilia and flagella associated protein 410" O43822 21 44328944-44339402 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, DNA damage" "Ciliopathy, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 30.8;Extravillous trophoblasts: 15.7;Hofbauer cells: 35.5;Syncytiotrophoblasts: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030283, HPA030284, CAB034126, CAB034128" Supported Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "Vesicles, Cytosol" "CAB034126: AB_1564257, CAB034128: AB_1564259, HPA030283: , HPA030284: AB_10602700" "unprognostic (1.84e-1)" "unprognostic (1.56e-1)" "unprognostic (3.14e-2)" "unprognostic (1.29e-2)" "unprognostic (2.11e-3)" "unprognostic (1.36e-1)" "unprognostic (6.58e-2)" "unprognostic (1.13e-2)" "unprognostic (9.73e-2)" "unprognostic (2.77e-1)" "prognostic favorable (1.32e-4)" "unprognostic (1.49e-1)" "prognostic favorable (4.08e-4)" "unprognostic (2.98e-1)" "unprognostic (2.79e-1)" "unprognostic (1.32e-2)" "unprognostic (1.06e-1)" 19.8 22.2 14.5 5.1 14.6 11.4 19.5 13.8 18.6 22.9 12.7 21.1 6.5 23.4 2.3 12.5 26.3 3.8 19.9 14.9 14.5 26.0 26.8 18.5 6.6 16.5 16.8 22.3 24.0 7.5 34.4 3.3 14.5 26.3 1.4 10.0 18.6 5.0 16.1 17.9 19.2 2.4 13.9 20.9 20.7 30.9 18.5 4.2 32.8 4.9 2.3 19.2 14.8 16.2 12.9 5.2 4.9 6.3 3.2 2.0 19.3 6.4 3.7 2.5 1.3 9.4 3.7 9.1 12.5 2.2 5.1 6.0 0.9 1.2 0.6 14.2 12.9 9.5 4.3 11.2 4.1 10.2 9.8 2.9 2.2 1.0 2.2 4.4 1.6 6.7 11.6 15.1 1.6 15.5 11.2 25.0 12.2 6.4 7.8 28.6 6.3 20.3 2.9 18.0 12.9 12.2 8.9 2.1 11.0 2.9 9.3 22.0 7.5 5.4 6.9 5.8 4.9 25.1 14.2 6.4 13.2 20.4 9.9 1.7 10.2 1.6 9.4 12.6 11.3 16.6 10.0 13.2 10.5 11.6 11.3 11.1 1.3 17.3 9.5 31.3 6.1 7.6 14.5 14.6 13.8 18.6 14.9 14.5 16.5 16.8 14.5 13.9 18.5 16.2 5.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 30.8 6.9 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 15.7 7.4 0.0 0.0 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 32.7 1.1 0.0 0.0 0.0 CFAP43 "bA373N18.2, C10orf79, FLJ22944, FLJ36006, WDR96" ENSG00000197748 "Cilia and flagella associated protein 43" Q8NDM7 10 104129888-104232364 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 34.7;choroid plexus: 80.2;fallopian tube: 48.9;testis: 57.3" "Cell type enhanced" "Detected in many" "Early spermatids: 103.0;Endometrial ciliated cells: 161.0;Late spermatids: 58.4;Respiratory ciliated cells: 231.0;Spermatocytes: 53.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.3;U-266/70: 3.3;U-266/84: 2.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 5.9" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.20e-2)" "unprognostic (3.05e-2)" "unprognostic (3.61e-2)" "unprognostic (6.46e-3)" "unprognostic (2.03e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "unprognostic (1.78e-1)" "unprognostic (1.56e-1)" "unprognostic (2.80e-1)" "unprognostic (6.88e-3)" "unprognostic (2.18e-1)" "unprognostic (1.76e-1)" "unprognostic (3.41e-1)" "unprognostic (3.35e-2)" "unprognostic (9.11e-4)" "unprognostic (6.67e-2)" 0.3 1.0 8.4 0.2 8.2 0.2 2.5 4.7 4.3 6.0 80.2 0.3 0.4 2.9 7.8 0.2 48.9 0.9 0.2 8.8 10.5 5.9 0.4 8.2 0.3 33.9 34.7 1.8 2.2 3.8 10.1 0.3 23.5 1.5 0.2 10.7 0.9 1.3 0.1 1.0 0.6 0.2 23.8 0.2 0.6 57.3 9.8 0.4 5.3 0.0 0.2 0.2 0.5 14.6 1.7 0.6 0.6 1.1 0.0 0.3 0.1 0.0 0.5 0.3 0.2 0.0 4.3 0.0 0.0 0.0 1.5 0.6 0.1 0.6 0.7 0.2 0.7 0.0 0.3 0.2 0.1 0.0 0.1 0.4 0.5 0.4 0.3 0.9 0.1 0.3 1.2 0.1 0.0 1.1 0.1 0.2 0.1 0.4 0.2 0.1 0.0 0.0 1.5 0.0 0.9 0.9 0.4 0.0 0.8 0.5 0.5 0.0 0.0 0.1 0.3 0.5 0.2 3.3 2.9 0.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.4 8.2 4.7 4.3 8.8 10.5 33.9 34.7 23.5 23.8 9.8 14.6 0.3 3.2 8.4 16.6 0.1 0.0 0.6 0.0 0.6 0.8 1.9 1.7 0.8 0.0 38.4 1.8 10.4 0.1 0.0 0.0 0.0 1.2 103.0 161.0 2.1 1.0 3.6 0.8 16.6 0.0 0.2 1.2 1.1 3.6 6.3 0.6 0.4 0.1 0.1 0.0 23.5 0.1 0.0 0.0 0.0 58.4 1.5 0.7 0.0 1.9 0.6 1.3 0.0 1.5 6.1 0.2 0.1 2.2 0.2 0.6 0.1 1.2 231.0 8.8 0.0 0.6 0.1 53.7 4.4 0.3 0.0 0.0 0.7 0.4 0.2 0.3 CFAP53 "CCDC11, FLJ32743" ENSG00000172361 "Cilia and flagella associated protein 53" Q96M91 18 50227193-50266495 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Ciliopathy, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "fallopian tube: 28.5;testis: 79.6" "Group enriched" "Detected in many" 14 "Early spermatids: 809.6;Endometrial ciliated cells: 331.5;Late spermatids: 528.4;Respiratory ciliated cells: 216.5;Spermatocytes: 481.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-HME1: 4.7" "HPA041069, HPA066142" Enhanced Approved Midbody Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Midbody "HPA041069: AB_10805835, HPA066142: AB_2732739" "unprognostic (1.73e-2)" "unprognostic (1.13e-2)" "unprognostic (5.83e-2)" "unprognostic (3.12e-3)" "unprognostic (3.31e-2)" "unprognostic (1.19e-1)" "unprognostic (3.64e-4)" "unprognostic (2.90e-2)" "unprognostic (3.68e-2)" "unprognostic (9.75e-3)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "prognostic favorable (5.85e-4)" "unprognostic (3.22e-1)" "unprognostic (1.17e-2)" "unprognostic (4.34e-3)" "unprognostic (4.61e-3)" 0.3 1.2 3.0 0.4 3.4 0.7 1.1 5.0 3.2 2.0 8.5 0.5 0.2 1.1 5.7 0.4 28.5 0.7 0.5 3.1 3.7 2.7 0.4 3.3 0.3 6.8 7.8 1.0 1.1 2.5 3.3 0.3 6.0 0.9 0.2 3.5 0.6 1.2 2.3 1.0 0.4 0.3 5.3 0.4 0.5 79.6 3.4 0.5 3.9 0.4 0.2 0.6 0.6 5.0 1.2 0.8 0.5 1.0 0.7 1.3 0.9 0.2 0.1 0.1 0.2 0.1 1.0 0.7 0.7 0.3 0.3 0.5 0.3 0.5 0.2 0.5 0.7 0.3 0.3 0.1 0.3 0.5 0.4 0.4 2.0 0.5 4.7 1.1 0.3 1.9 1.4 0.4 0.3 1.2 1.2 0.2 0.2 0.2 0.5 0.1 0.2 1.0 1.4 0.0 0.8 0.6 0.1 0.0 0.4 1.3 0.6 0.1 0.0 0.7 0.5 0.4 0.4 2.1 0.8 0.1 0.7 0.5 0.1 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.1 0.0 0.2 0.0 0.2 0.2 0.0 3.0 3.4 5.0 3.2 3.1 3.7 6.8 7.8 6.0 5.3 3.4 5.0 0.6 6.4 4.2 2.6 0.6 0.0 2.0 0.0 1.8 4.3 4.7 3.8 0.4 0.0 21.1 9.2 8.4 1.7 0.2 0.3 9.8 3.4 809.6 331.5 3.8 1.4 0.0 0.4 3.8 0.6 0.5 2.2 2.6 7.9 1.3 1.4 1.8 1.0 0.4 1.7 4.4 0.2 0.0 0.0 0.0 528.4 8.4 1.3 0.0 2.8 1.0 2.7 1.0 3.0 6.5 0.8 0.1 5.7 0.9 1.3 0.8 20.5 216.5 10.5 6.6 2.1 0.7 481.5 32.5 1.3 0.0 0.7 1.0 1.7 0.4 1.1 CFC1 "CRYPTIC, HTX2" ENSG00000136698 "Cripto, FRL-1, cryptic family 1" P0CG37 2 130592165-130599575 "Disease related genes, Human disease related genes, Predicted secreted proteins" Gastrulation "Developmental protein" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 24.0;pancreas: 30.7;pituitary gland: 59.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 14.9;Enteroendocrine cells: 20.5" "Cancer enriched" "Detected in some" 7 "pancreatic cancer: 4.3" "Region enhanced" "Detected in all" "hypothalamus: 24.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "RPMI-8226: 12.1;SCLC-21H: 6.7;SuSa: 4.0" HPA041773 Uncertain "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA041773: AB_2677664" "unprognostic (6.65e-2)" "unprognostic (2.19e-3)" "unprognostic (1.11e-3)" "unprognostic (2.01e-1)" 1.7 0.6 4.6 0.0 2.3 0.0 0.0 2.9 3.5 0.1 0.0 0.2 0.0 0.2 0.1 0.0 1.5 0.0 1.9 1.3 24.0 0.0 0.0 0.1 0.0 3.9 8.1 0.0 30.7 0.0 59.3 0.0 5.6 7.2 0.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 10.7 0.6 8.6 5.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 2.3 2.9 3.5 1.3 24.0 3.9 8.1 5.6 3.9 8.6 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 20.5 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "CF transmembrane conductance regulator" P13569 7 117287120-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.6;intestine: 42.7;pancreas: 210.7" "Group enriched" "Detected in many" 4 "Ductal cells: 485.4;Ionocytes: 252.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "CACO-2: 29.5;MOLT-4: 98.9;U-266/70: 49.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB001951: , HPA021939: AB_1846578, HPA079652: " "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" 0.4 0.0 0.5 4.7 2.0 0.0 0.4 0.7 1.3 8.5 0.0 42.7 36.2 1.1 1.1 0.8 2.2 54.6 0.1 0.3 0.7 2.1 1.6 8.2 0.0 1.1 0.7 0.0 210.7 0.2 0.1 0.6 0.7 2.2 40.7 0.0 21.5 0.5 0.0 1.9 19.9 2.0 1.7 0.0 3.1 1.7 1.0 0.1 0.1 0.0 0.3 0.7 0.0 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 98.9 0.1 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 49.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.7 1.3 0.3 0.7 1.1 0.7 0.7 1.7 1.0 2.9 0.0 6.4 65.6 0.0 0.5 0.0 2.0 2.6 0.0 0.5 0.5 0.0 2.4 55.8 17.8 0.0 0.0 0.0 0.0 45.8 0.0 485.4 3.2 9.6 1.2 0.4 7.2 0.0 2.2 4.5 0.0 0.3 4.1 19.8 1.3 0.1 0.0 0.4 0.0 0.0 1.1 13.9 252.3 0.0 0.0 2.6 0.3 0.1 0.0 1.0 6.7 0.5 0.0 0.5 23.8 14.8 86.4 0.0 0.0 4.0 8.6 0.0 5.6 0.0 0.0 0.0 1.6 2.2 0.5 0.0 0.0 0.0 0.3 0.1 87.3 5.8 CHD4 "Mi-2b, Mi2-BETA" ENSG00000111642 "Chromodomain helicase DNA binding protein 4" Q14839 12 6570082-6614524 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA012008 Supported Enhanced Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA012008: AB_1846633" "unprognostic (6.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.71e-2)" "unprognostic (6.40e-3)" "unprognostic (8.99e-2)" "unprognostic (3.36e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (2.66e-2)" "unprognostic (1.05e-1)" "unprognostic (6.85e-2)" "unprognostic (3.15e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (3.33e-1)" "unprognostic (1.82e-1)" "unprognostic (9.84e-2)" "unprognostic (1.66e-1)" 34.5 45.6 22.9 38.6 30.7 44.4 31.9 24.6 30.1 39.4 20.6 45.7 26.5 47.8 44.9 35.4 37.7 31.1 41.4 19.7 26.1 39.3 31.6 35.3 46.3 27.3 29.2 40.9 37.7 58.3 33.5 42.2 28.0 28.4 35.4 44.9 33.8 44.1 50.0 45.8 35.5 49.9 22.6 39.0 38.5 34.2 29.6 90.7 54.6 38.7 56.6 42.2 34.4 27.4 86.7 79.7 187.6 72.1 76.6 84.7 110.4 92.9 93.4 102.3 93.5 130.6 66.6 184.9 36.0 107.5 66.1 76.0 179.1 104.5 135.7 139.9 92.7 258.5 122.0 83.3 67.1 207.2 119.1 82.9 51.7 99.1 68.7 128.2 122.2 101.6 209.0 91.0 98.7 111.8 196.6 67.8 184.7 82.5 72.7 166.4 114.9 103.6 64.2 101.6 88.8 114.6 121.1 136.0 92.9 205.4 61.3 121.3 114.4 103.4 217.4 76.3 111.5 144.0 91.8 230.2 68.7 125.8 79.5 12.3 6.8 8.7 9.3 7.7 9.6 8.8 8.4 9.3 6.9 11.3 10.6 10.3 10.8 12.2 8.0 14.4 15.9 5.6 22.9 30.7 24.6 30.1 19.7 26.1 27.3 29.2 28.0 22.6 29.6 27.4 68.2 60.9 119.7 56.2 82.8 68.6 47.4 42.4 76.2 109.9 77.5 61.2 132.9 58.6 67.2 88.3 70.9 48.2 106.0 58.1 13.7 84.6 76.4 128.1 153.3 78.9 97.1 64.4 26.1 71.9 46.1 67.7 47.9 123.7 85.9 73.0 56.0 69.2 69.0 139.7 21.4 66.6 54.9 51.9 78.3 59.1 65.9 68.9 48.0 25.3 66.7 71.4 56.7 24.6 55.5 95.8 36.4 74.4 69.0 49.4 45.8 38.3 82.1 57.8 52.6 112.1 98.1 102.6 111.6 78.9 67.6 68.0 85.1 83.7 72.1 47.4 CHD7 "CRG, FLJ20357, FLJ20361, KIAA1416" ENSG00000171316 "Chromodomain helicase DNA binding protein 7" Q9P2D1 8 60678740-60868028 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 241.8;Oligodendrocyte precursor cells: 298.6;Oligodendrocytes: 255.7;Rod photoreceptor cells: 198.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 15 "B-cells: 14.9;granulocytes: 17.6;T-cells: 6.6" "Cell line enhanced" "Detected in many" "AF22: 51.5;SCLC-21H: 46.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053075 Supported Nucleoplasm,Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Nucleoli "HPA053075: AB_2682035" "unprognostic (3.77e-2)" "unprognostic (3.28e-3)" "unprognostic (3.17e-2)" "prognostic unfavorable (5.34e-5)" "unprognostic (9.59e-2)" "unprognostic (1.14e-1)" "unprognostic (1.86e-3)" "unprognostic (3.41e-2)" "unprognostic (3.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (9.09e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-1)" "unprognostic (8.20e-2)" "unprognostic (2.17e-1)" 3.6 1.9 10.3 3.9 17.2 22.1 3.5 71.5 11.0 2.0 2.5 4.6 4.6 2.2 2.2 4.9 2.3 1.9 3.8 9.4 11.5 3.8 3.2 4.6 5.8 19.7 17.2 1.0 4.4 5.3 6.1 4.3 18.8 2.7 4.0 23.7 3.9 1.7 10.4 5.2 6.4 1.7 11.4 5.6 3.5 2.9 15.6 2.6 4.1 4.1 5.7 3.4 3.2 17.7 8.0 4.0 51.5 9.2 0.1 0.0 16.2 0.4 0.1 1.8 1.6 10.0 7.3 15.5 0.9 0.1 2.3 4.8 26.7 7.9 1.6 5.9 14.3 36.5 7.0 13.2 2.1 11.1 6.5 1.0 5.9 0.0 8.5 3.1 7.7 12.5 2.7 13.4 1.2 8.3 17.5 12.7 35.4 8.1 1.8 36.0 12.1 5.0 4.1 9.1 46.9 23.2 1.4 5.9 14.9 18.0 10.5 10.5 9.0 0.5 8.3 0.5 4.3 14.2 8.7 23.7 3.0 1.2 13.4 14.9 0.4 17.6 3.2 0.2 4.1 10.1 3.6 1.1 0.1 14.9 6.6 2.4 9.3 0.0 0.8 0.8 0.3 0.6 10.3 17.2 71.5 11.0 9.4 11.5 19.7 17.2 18.8 11.4 15.6 17.7 35.9 32.1 17.5 68.6 64.3 30.3 35.9 10.8 9.6 36.3 16.6 14.6 35.8 27.1 20.7 16.5 241.8 8.2 17.4 31.8 1.9 17.7 15.9 34.0 4.1 40.5 87.3 3.8 6.8 11.3 8.6 6.4 28.5 37.6 41.0 39.8 21.4 12.6 14.9 70.7 17.8 39.9 32.6 10.8 10.4 8.9 0.9 13.6 21.4 118.0 13.9 121.3 15.5 298.6 255.7 16.9 27.4 0.4 29.1 42.9 17.4 5.4 20.4 198.5 0.0 49.7 9.8 8.0 12.9 25.5 32.4 6.2 21.4 3.0 34.1 35.8 CHMP1A "CHMP1, KIAA0047, PCOLN3, PRSM1, Vps46A" ENSG00000131165 "Charged multivesicular body protein 1A" Q9HD42 16 89640816-89657738 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transcription, Transcription regulation, Transport" Repressor Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA006776 Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Centrosome, Cytosol" "HPA006776: AB_1078520" "unprognostic (7.12e-2)" "unprognostic (1.64e-2)" "unprognostic (1.08e-1)" "unprognostic (1.41e-2)" "unprognostic (7.29e-2)" "unprognostic (8.03e-3)" "unprognostic (1.28e-3)" "unprognostic (3.92e-3)" "unprognostic (2.42e-1)" "unprognostic (3.53e-1)" "unprognostic (2.21e-1)" "unprognostic (2.56e-1)" "unprognostic (7.98e-3)" "unprognostic (1.59e-2)" "unprognostic (4.19e-2)" "unprognostic (3.24e-1)" "unprognostic (1.73e-1)" 30.3 31.2 46.3 21.1 44.5 31.4 29.4 41.2 53.4 34.3 36.9 42.7 37.8 35.8 17.0 65.4 31.6 24.8 33.1 46.8 42.7 36.6 30.6 28.7 27.5 45.3 44.3 25.0 25.7 30.4 24.8 24.7 44.0 33.5 23.0 5.4 31.8 22.1 50.0 48.7 42.5 22.4 44.3 31.6 34.0 37.3 45.7 30.5 28.3 25.9 24.3 35.6 36.9 44.2 70.5 66.3 29.5 46.2 42.2 38.2 75.3 53.0 54.3 79.3 38.7 97.1 111.5 37.7 53.2 70.1 52.9 88.3 52.6 69.7 36.7 34.2 82.7 31.0 23.4 108.5 57.8 23.0 31.7 54.7 75.6 74.6 33.8 42.7 41.2 46.2 69.9 18.2 45.6 141.4 55.1 88.3 58.1 78.6 63.5 60.1 58.3 39.8 60.4 43.0 52.7 70.8 103.5 34.3 38.1 27.5 117.6 48.5 63.1 52.7 61.6 65.3 45.8 52.1 59.1 51.1 88.1 54.9 62.5 66.7 51.6 108.9 54.4 62.7 42.0 36.3 43.6 50.1 44.2 33.4 27.5 33.4 86.0 49.8 82.3 49.4 58.5 64.1 46.3 44.5 41.2 53.4 46.8 42.7 45.3 44.3 44.0 44.3 45.7 44.2 31.1 32.1 23.6 17.3 27.5 23.8 24.5 28.8 13.1 24.6 33.9 27.6 16.8 28.6 26.6 31.3 8.4 57.7 43.2 147.3 37.2 55.3 56.4 27.2 26.3 28.3 44.3 16.2 8.8 59.5 74.4 26.9 36.2 35.0 27.9 33.0 23.2 31.1 47.6 43.7 7.9 57.7 30.5 30.4 23.8 125.5 20.5 28.3 23.2 11.2 62.8 36.3 43.3 11.1 9.5 84.7 121.6 24.0 14.8 31.7 109.6 40.9 22.4 20.5 26.3 17.1 27.1 45.4 33.3 26.3 32.5 66.2 28.6 28.8 58.2 36.5 CHRNA1 CHRNA ENSG00000138435 "Cholinergic receptor nicotinic alpha 1 subunit" P02708 2 174747592-174787935 "Disease related genes, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 170.1" "Cell type enriched" "Detected in some" 48 "Skeletal myocytes: 193.5" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Group enriched" "Detected in some" 13 "cerebral cortex: 12.8;hippocampal formation: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "LHCN-M2: 445.4;RH-30: 360.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071554 Enhanced Supported "Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA071554: AB_2686416" "unprognostic (1.49e-1)" "unprognostic (1.97e-1)" "unprognostic (1.22e-3)" "unprognostic (2.28e-2)" "unprognostic (2.96e-1)" "unprognostic (8.55e-3)" "unprognostic (5.34e-2)" "unprognostic (5.29e-3)" "unprognostic (9.59e-2)" "unprognostic (9.64e-2)" "unprognostic (9.66e-2)" "unprognostic (6.37e-2)" "unprognostic (4.18e-4)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" "unprognostic (1.86e-1)" "unprognostic (7.18e-2)" 0.2 0.0 0.2 0.2 0.4 0.0 0.5 0.1 12.8 0.6 0.2 1.5 0.2 0.0 0.2 0.6 0.0 0.0 0.3 5.5 0.2 0.0 0.2 0.6 0.8 0.5 0.2 0.0 0.0 0.0 3.3 0.2 0.5 2.0 0.9 0.0 3.2 0.0 170.1 0.5 0.0 0.0 0.3 0.0 0.0 0.4 0.3 1.1 0.0 20.4 1.2 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 21.5 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.2 445.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 360.2 0.0 0.0 0.3 2.9 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.4 0.1 12.8 5.5 0.2 0.5 0.2 0.5 0.3 0.3 0.7 0.1 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 4.0 0.0 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.5 0.0 0.6 0.4 1.7 0.3 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 193.5 0.3 0.1 0.2 0.0 0.0 0.0 1.8 0.0 0.2 0.0 CHRND ACHRD ENSG00000135902 "Cholinergic receptor nicotinic delta subunit" Q07001 2 232525993-232536667 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skeletal muscle: 57.6" "Group enriched" "Detected in some" 10 "Muller glia cells: 4.0;Skeletal myocytes: 4.4" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 49 "RH-30: 99.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA056404, HPA065404" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA056404: AB_2732603, HPA065404: AB_2732734" "unprognostic (1.69e-2)" "unprognostic (7.93e-2)" "unprognostic (3.28e-3)" "unprognostic (7.75e-3)" "unprognostic (6.04e-2)" "unprognostic (1.10e-1)" "unprognostic (7.25e-2)" "unprognostic (1.90e-1)" "unprognostic (4.97e-8)" "unprognostic (7.52e-2)" "unprognostic (2.86e-1)" "unprognostic (2.46e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 6.3 0.7 0.0 57.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 99.4 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CHRNG ACHRG ENSG00000196811 "Cholinergic receptor nicotinic gamma subunit" P07510 2 232539692-232548115 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "skeletal muscle: 32.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "HSkMC: 2.7;RH-30: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (2.26e-1)" "unprognostic (8.97e-2)" "unprognostic (5.61e-2)" "unprognostic (1.92e-2)" "unprognostic (4.38e-1)" "unprognostic (4.86e-3)" "unprognostic (2.32e-1)" "unprognostic (1.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "unprognostic (4.18e-2)" "unprognostic (4.32e-1)" "unprognostic (4.19e-6)" "unprognostic (6.13e-2)" "unprognostic (8.66e-2)" "unprognostic (1.86e-1)" "unprognostic (3.24e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.2 0.1 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CHST14 "D4ST-1, D4ST1, HD4ST" ENSG00000169105 "Carbohydrate sulfotransferase 14" Q8NCH0 15 40470984-40473158 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.5;Extravillous trophoblasts: 32.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057697, HPA071601" Enhanced Approved "Golgi apparatus" NA NA 20000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" "HPA057697: AB_2683505, HPA071601: AB_2686425" "unprognostic (5.46e-2)" "unprognostic (9.23e-2)" "unprognostic (4.03e-2)" "unprognostic (2.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.86e-1)" "unprognostic (2.96e-2)" "unprognostic (6.94e-2)" "unprognostic (1.70e-1)" "unprognostic (9.95e-2)" "unprognostic (2.84e-1)" "unprognostic (3.17e-2)" "unprognostic (5.85e-3)" "unprognostic (2.01e-3)" "unprognostic (1.94e-1)" "unprognostic (6.34e-2)" "unprognostic (2.25e-2)" 14.2 9.6 6.8 7.7 7.5 3.4 13.7 7.0 6.5 22.0 7.3 11.8 4.5 21.6 8.0 8.7 16.5 11.3 13.8 6.2 7.0 10.1 8.8 13.0 8.5 8.0 7.1 21.1 8.1 11.3 14.4 27.0 7.2 14.6 4.6 1.6 11.0 15.4 5.0 9.1 9.9 12.6 7.5 13.6 9.4 7.9 7.0 8.6 15.8 7.4 7.5 16.1 16.1 7.3 26.2 17.1 26.4 71.6 40.4 31.0 43.0 25.2 47.3 43.5 40.9 21.2 12.8 4.3 37.6 42.7 76.7 43.7 23.7 14.2 20.3 31.5 15.0 13.4 16.9 19.8 22.5 5.7 33.4 38.3 11.6 15.4 11.6 47.8 39.2 15.1 13.6 15.0 32.6 20.1 9.6 29.8 17.0 7.9 20.1 26.2 33.4 7.6 29.5 13.3 19.7 30.2 22.2 24.4 8.4 31.9 35.7 23.9 31.9 73.0 27.1 23.3 25.5 30.3 22.6 12.2 32.8 19.6 53.7 7.6 1.1 2.2 2.2 1.1 0.6 0.3 1.1 1.9 2.0 1.1 0.9 0.8 0.1 3.3 0.6 0.7 0.8 0.7 6.8 7.5 7.0 6.5 6.2 7.0 8.0 7.1 7.2 7.5 7.0 7.3 10.6 12.8 1.1 2.0 5.8 3.4 5.4 4.1 9.1 0.6 5.8 9.7 3.2 7.2 4.6 3.7 0.0 46.5 3.5 0.5 0.0 7.7 1.8 3.2 14.5 10.2 2.4 10.7 0.1 4.9 32.4 19.3 0.0 5.6 4.5 14.9 15.4 3.7 9.3 1.7 0.1 1.4 2.0 5.6 3.3 1.3 17.7 5.6 5.4 2.8 3.4 9.8 6.2 2.0 0.5 5.2 0.3 11.7 1.9 3.6 0.2 1.1 3.0 0.8 6.6 11.8 9.2 7.5 1.3 5.6 2.6 13.5 4.9 3.9 1.9 1.3 CHST3 "C6ST, C6ST1" ENSG00000122863 "Carbohydrate sulfotransferase 3" Q7LGC8 10 71964395-72013558 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 26.9;Oligodendrocyte precursor cells: 26.7;Oligodendrocytes: 27.1;Skeletal myocytes: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-251 MG: 65.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA047523, HPA055704" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 690000 "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Cytosol" "HPA047523: AB_2680075, HPA055704: AB_2682891" "unprognostic (1.10e-2)" "unprognostic (1.93e-1)" "unprognostic (1.13e-3)" "unprognostic (1.16e-3)" "unprognostic (2.44e-1)" "unprognostic (4.67e-2)" "unprognostic (4.79e-2)" "unprognostic (7.53e-2)" "unprognostic (7.99e-2)" "unprognostic (3.71e-2)" "unprognostic (2.83e-3)" "unprognostic (5.99e-2)" "unprognostic (1.40e-2)" "unprognostic (2.65e-2)" "unprognostic (7.77e-2)" "unprognostic (2.56e-2)" "unprognostic (2.54e-3)" 18.4 13.4 10.7 5.5 17.9 0.0 11.4 16.8 11.5 10.7 6.2 11.9 0.9 16.0 3.7 6.4 12.9 4.7 14.3 9.9 12.9 7.9 1.2 7.9 1.6 27.9 18.2 20.6 4.6 1.2 4.6 8.0 19.8 11.1 2.1 2.1 6.4 14.8 17.7 8.7 5.4 17.1 14.0 2.5 14.7 18.1 17.3 4.2 5.5 9.0 1.4 9.4 8.4 25.3 15.4 16.4 8.2 20.3 36.6 14.4 0.3 32.0 30.4 19.3 12.8 14.4 30.1 0.0 21.4 37.9 15.5 19.7 7.4 21.9 15.3 0.4 5.5 0.1 27.8 13.8 18.7 0.0 0.1 19.8 24.9 19.0 25.9 37.3 5.7 0.7 4.7 0.0 20.6 0.4 0.0 0.1 3.5 0.5 5.3 0.2 9.9 0.0 26.9 15.7 0.5 8.1 24.2 0.6 24.1 9.9 1.8 3.1 11.9 23.6 27.1 39.6 65.1 0.0 0.1 0.1 17.2 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 17.9 16.8 11.5 9.9 12.9 27.9 18.2 19.8 14.0 17.3 25.3 23.9 0.0 1.9 14.0 0.1 2.8 4.9 6.1 13.6 0.1 4.3 8.0 10.4 5.7 2.5 7.3 0.0 4.6 0.0 0.1 3.9 9.7 0.8 20.1 24.7 5.6 0.0 0.0 0.2 2.7 2.2 9.3 2.6 17.9 1.3 26.9 13.6 0.3 0.8 0.0 0.3 0.0 2.0 0.6 1.9 3.2 20.5 0.7 8.8 4.7 0.7 6.6 0.0 26.7 27.1 12.7 0.0 21.8 0.0 4.2 0.0 3.6 2.0 0.2 6.6 26.8 13.9 1.0 2.1 7.5 2.4 1.1 0.4 5.5 0.1 1.3 CHST8 GALNAC-4-ST1 ENSG00000124302 "Carbohydrate sulfotransferase 8" Q9H2A9 19 33621953-33773509 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 25 "brain: 30.3;pituitary gland: 63.9" "Cell type enhanced" "Detected in some" "Early spermatids: 15.4;Excitatory neurons: 11.8;Granulosa cells: 7.9;Late spermatids: 56.5;Oligodendrocyte precursor cells: 12.1" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;glioma: 4.9;testis cancer: 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "RPMI-8226: 24.7;SCLC-21H: 13.5;SH-SY5Y: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016004 Enhanced "Intracellular and membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA016004: AB_1846731" "unprognostic (1.00e-1)" "unprognostic (6.58e-2)" "unprognostic (1.21e-1)" "unprognostic (1.45e-2)" "unprognostic (9.44e-2)" "unprognostic (2.96e-2)" "unprognostic (1.15e-2)" "unprognostic (5.75e-2)" "unprognostic (8.41e-2)" "unprognostic (1.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.54e-1)" "unprognostic (6.98e-8)" "unprognostic (9.37e-3)" "unprognostic (2.61e-1)" "unprognostic (3.28e-1)" "unprognostic (3.87e-2)" 0.7 0.7 7.8 0.3 6.7 0.0 1.8 11.5 10.4 0.9 0.1 0.4 0.0 0.6 0.0 0.3 1.2 0.9 0.4 11.0 11.4 0.1 0.1 0.2 0.4 29.8 7.2 1.0 0.7 0.0 63.9 0.0 30.3 0.7 0.0 0.7 0.2 0.0 0.1 0.3 0.3 0.1 5.4 1.3 0.3 1.4 11.5 0.0 0.6 0.0 0.2 0.3 0.5 8.2 0.0 0.0 0.0 0.3 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 4.7 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 3.6 0.0 0.0 0.0 0.1 24.7 0.0 0.4 13.5 23.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.8 6.7 11.5 10.4 11.0 11.4 29.8 7.2 30.3 5.4 11.5 8.2 0.2 0.0 0.0 0.7 0.0 0.8 0.4 0.0 0.0 3.1 3.8 0.6 5.1 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.3 0.2 0.4 0.0 0.0 11.8 0.0 1.3 0.2 0.0 0.1 0.0 7.9 0.4 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 56.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 12.1 3.6 0.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 4.7 0.0 0.3 3.2 0.5 0.7 0.3 0.1 0.0 0.0 0.0 0.0 1.1 CHSY1 "CSS1, KIAA0990" ENSG00000131873 "Chondroitin sulfate synthase 1" Q86X52 15 101175727-101252048 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (7.28e-2)" "unprognostic (6.39e-2)" "unprognostic (9.24e-2)" "unprognostic (1.55e-1)" "unprognostic (7.60e-2)" "unprognostic (9.51e-3)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (1.77e-1)" "unprognostic (1.32e-2)" "unprognostic (5.97e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.33e-5)" "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" 27.5 18.6 10.3 18.5 9.8 23.0 21.7 9.0 11.8 19.5 14.4 7.7 6.0 17.3 9.5 10.8 14.9 22.7 20.1 9.2 10.3 13.7 10.0 23.6 11.6 14.2 13.8 19.7 7.3 7.4 8.5 46.7 11.9 14.4 8.2 7.0 10.1 11.4 6.5 15.0 7.7 20.0 11.5 13.9 10.4 8.7 12.5 10.5 10.0 7.4 10.3 34.8 14.0 9.8 9.1 11.2 36.8 18.7 18.9 25.0 24.5 21.8 19.2 25.8 26.2 9.7 7.1 22.0 12.7 36.3 16.8 24.7 24.5 27.7 28.2 24.6 12.4 43.4 12.2 11.4 23.3 66.9 42.9 23.2 22.8 22.3 20.1 29.3 30.8 9.7 16.2 216.3 19.7 7.9 9.2 46.3 42.5 17.7 7.9 20.6 36.9 32.8 18.1 17.7 6.4 34.6 23.0 11.1 40.8 29.8 12.6 81.6 26.2 41.9 24.1 20.0 46.5 38.2 94.5 12.7 32.5 62.2 32.0 0.0 1.3 2.9 1.5 0.8 1.7 0.9 0.9 1.6 0.8 1.0 0.5 1.0 4.9 0.7 0.9 0.5 1.8 0.6 10.3 9.8 9.0 11.8 9.2 10.3 14.2 13.8 11.9 11.5 12.5 9.8 55.0 0.0 15.7 27.7 11.4 57.9 20.7 10.1 20.5 10.7 41.9 29.8 9.3 5.7 9.4 16.5 6.2 6.1 14.6 1.6 1.9 5.3 1.2 10.0 33.4 45.8 3.0 12.0 34.2 2.2 28.8 40.0 5.1 13.8 25.9 51.9 60.0 5.4 16.6 38.7 36.1 3.6 10.2 17.8 37.1 2.5 55.0 41.2 26.6 59.0 10.2 9.2 10.3 21.1 24.2 5.5 2.5 47.0 9.3 19.3 1.2 2.4 8.1 7.5 46.0 47.9 53.5 3.9 7.5 10.5 62.5 13.8 15.2 23.0 3.9 10.2 CHUK "IkBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16" ENSG00000213341 "Component of inhibitor of nuclear factor kappa B kinase complex" O15111 10 100188300-100229596 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001402, CAB004240, CAB018564" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "CAB004240: AB_627784, CAB018564: AB_649197, HPA001402: AB_1079125" "unprognostic (8.61e-3)" "unprognostic (1.70e-1)" "unprognostic (3.74e-2)" "unprognostic (3.01e-1)" "unprognostic (3.02e-2)" "unprognostic (5.93e-2)" "unprognostic (4.02e-2)" "unprognostic (2.09e-1)" "unprognostic (8.58e-2)" "unprognostic (8.39e-2)" "unprognostic (6.73e-2)" "unprognostic (1.49e-1)" "prognostic favorable (1.27e-4)" "unprognostic (2.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-3)" "unprognostic (2.22e-1)" 13.5 10.3 6.6 11.7 7.6 19.6 10.8 7.1 8.3 8.4 8.3 11.9 12.8 8.8 9.1 9.7 7.5 9.0 6.8 6.4 9.2 21.0 17.0 10.2 12.7 7.3 7.5 5.6 11.5 14.0 6.5 10.5 7.6 9.6 13.3 8.0 8.8 9.0 14.2 6.9 10.8 11.8 7.7 9.9 11.2 8.3 8.7 14.3 11.1 11.7 12.6 13.6 6.4 8.7 27.7 22.9 23.0 34.4 21.6 19.3 17.6 34.3 33.5 31.3 38.0 25.9 15.9 37.2 19.7 23.5 21.8 26.7 38.7 18.2 34.9 39.8 33.5 24.7 18.0 28.7 18.4 46.2 34.8 15.5 19.1 36.2 35.0 21.8 22.7 30.1 28.5 29.9 34.6 16.7 36.9 28.4 15.0 21.8 16.5 23.7 25.5 17.0 19.9 17.6 13.7 20.3 18.6 14.2 30.9 18.0 28.5 27.8 23.9 19.6 21.9 21.5 39.7 34.9 33.7 35.7 21.3 36.9 15.8 1.0 1.2 2.1 0.9 1.9 1.5 1.6 1.1 1.6 1.4 1.0 1.3 1.5 2.8 1.8 1.3 0.8 1.2 0.5 6.6 7.6 7.1 8.3 6.4 9.2 7.3 7.5 7.6 7.7 8.7 8.7 11.4 12.8 11.5 17.9 10.8 19.8 7.1 5.1 8.0 6.3 7.3 4.8 9.2 7.2 5.9 5.5 2.1 6.5 14.1 12.2 11.7 7.1 7.6 8.9 8.6 8.4 6.0 12.0 22.7 11.8 7.8 6.5 7.7 12.7 8.2 6.2 7.1 14.4 10.6 13.5 21.3 8.0 8.2 16.9 12.7 8.0 6.2 11.7 7.2 19.7 15.6 4.5 9.2 20.6 27.7 10.4 6.0 6.0 18.5 9.6 9.5 20.0 6.4 5.0 19.7 7.8 12.0 16.4 12.9 13.2 19.0 13.8 11.1 10.1 6.6 10.6 CIBAR1 "FAM92A, FAM92A1, FLJ38979" ENSG00000188343 "CBY1 interacting BAR domain containing 1" A1XBS5 8 93698561-93731527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 110.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 13.3;Extravillous trophoblasts: 14.1;Fibroblasts: 8.4;Hofbauer cells: 6.4;Syncytiotrophoblasts: 3.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034760, HPA058942" Enhanced Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA034760: AB_10599947, HPA058942: AB_2732628" "unprognostic (2.65e-3)" "unprognostic (6.81e-2)" "unprognostic (2.48e-3)" "unprognostic (2.44e-1)" "unprognostic (1.62e-2)" "unprognostic (2.93e-1)" "unprognostic (3.56e-1)" "unprognostic (3.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (2.28e-3)" "unprognostic (1.97e-1)" "unprognostic (1.71e-1)" "unprognostic (6.85e-3)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (3.07e-2)" 14.3 23.9 17.5 5.6 18.8 3.5 10.9 18.6 25.0 16.5 22.9 14.2 3.2 16.0 26.2 5.0 13.1 14.1 25.3 17.8 16.2 20.2 18.5 9.9 5.7 13.4 14.5 18.0 21.1 21.5 20.8 10.1 13.3 12.1 5.9 14.1 5.7 11.6 10.3 6.6 7.7 15.0 12.9 5.7 9.8 110.2 17.1 5.0 14.5 11.1 3.1 14.6 9.3 17.4 37.8 20.0 52.9 54.6 55.8 78.9 14.0 34.2 49.8 45.2 43.5 3.5 8.6 3.2 42.7 50.7 52.0 26.6 54.0 32.5 41.0 1.2 29.5 21.5 20.8 18.7 64.1 1.0 5.5 50.4 14.3 44.3 36.0 64.9 49.0 18.1 13.4 1.7 35.8 14.2 23.8 4.1 22.2 0.8 1.1 2.3 39.7 0.8 35.3 8.7 15.3 18.7 24.4 0.5 41.6 23.7 8.2 11.8 27.2 44.2 17.4 46.3 28.0 2.6 2.7 1.2 38.8 3.0 15.8 0.1 1.7 0.0 0.1 1.2 0.2 0.4 0.4 0.1 2.9 0.0 0.1 0.3 0.0 1.3 0.1 0.3 0.8 0.5 17.5 18.8 18.6 25.0 17.8 16.2 13.4 14.5 13.3 12.9 17.1 17.4 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 14.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 CILK1 "ICK, KIAA0936, LCK2, MGC46090, MRK" ENSG00000112144 "Ciliogenesis associated kinase 1" Q9UPZ9 6 53001279-53061824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 11.0;Cytotrophoblasts: 20.6;Extravillous trophoblasts: 33.9;Syncytiotrophoblasts: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000791, HPA001113" Approved Supported "Nucleoli fibrillar center" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli fibrillar center" "HPA000791: AB_2732392, HPA001113: AB_1851385" "unprognostic (1.75e-2)" "unprognostic (1.02e-1)" "unprognostic (5.47e-2)" "unprognostic (2.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (1.82e-2)" "unprognostic (1.17e-3)" "unprognostic (5.11e-2)" "unprognostic (1.18e-1)" "unprognostic (8.28e-2)" "unprognostic (8.12e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (2.26e-1)" 7.9 17.9 10.2 4.9 11.0 2.7 10.7 8.4 9.7 8.9 5.1 8.7 9.8 8.0 5.5 8.6 7.4 6.9 8.5 6.8 7.8 4.5 7.5 6.3 5.2 9.4 11.6 9.5 5.0 7.3 1.7 12.1 8.8 9.9 10.7 17.4 17.9 7.3 4.0 8.7 10.4 7.4 8.8 5.6 12.9 4.5 14.9 10.1 6.3 5.0 6.2 6.5 5.8 12.8 7.8 2.9 14.6 10.0 8.9 14.0 17.0 6.9 12.4 10.8 12.3 4.1 2.4 5.7 4.0 21.0 3.5 5.0 17.6 7.1 14.2 19.9 7.0 4.2 3.3 22.3 4.5 5.2 5.4 12.5 7.6 4.6 5.3 7.7 10.2 12.1 8.1 22.6 24.9 6.7 5.6 6.4 5.6 27.0 6.3 8.8 6.5 7.5 4.5 5.6 23.6 10.6 6.7 16.3 9.6 14.2 9.5 10.9 8.5 17.2 8.0 6.5 17.1 6.3 4.8 2.2 3.5 5.0 8.5 2.8 1.0 2.2 1.7 0.8 1.5 1.2 1.2 1.4 1.0 1.5 1.4 1.2 0.5 1.1 0.9 1.4 1.7 0.8 10.2 11.0 8.4 9.7 6.8 7.8 9.4 11.6 8.8 8.8 14.9 12.8 6.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 20.6 5.7 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 33.9 5.3 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 58.1 0.8 0.0 0.0 0.0 CIT "CITK, CRIK, KIAA0949, STK21" ENSG00000122966 "Citron rho-interacting serine/threonine kinase" O14578 12 119685791-119877320 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 72.8;Excitatory neurons: 147.0;Inhibitory neurons: 139.8;Oligodendrocyte precursor cells: 82.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019082, HPA048812, HPA075506" Uncertain Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA019082: AB_1846803, HPA048812: AB_2680528, HPA075506: AB_2686752" "unprognostic (5.64e-2)" "unprognostic (5.00e-2)" "unprognostic (8.16e-2)" "unprognostic (5.12e-3)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (3.61e-6)" "unprognostic (6.02e-2)" "unprognostic (7.78e-2)" "unprognostic (4.42e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-2)" "unprognostic (2.55e-3)" "unprognostic (8.56e-2)" "unprognostic (1.50e-1)" "unprognostic (1.70e-1)" "unprognostic (3.30e-1)" 0.7 2.2 13.5 1.6 26.2 6.3 0.6 0.0 19.9 0.9 0.0 2.1 1.2 0.4 0.0 2.5 0.5 0.5 0.6 15.2 5.4 2.5 0.3 1.8 1.5 0.2 5.0 0.3 0.2 0.1 1.6 1.4 0.4 0.5 2.5 3.4 0.8 0.2 0.5 1.6 1.9 0.9 0.9 3.0 2.2 4.8 14.2 6.8 0.6 0.3 2.3 0.5 1.3 6.6 26.2 20.6 21.7 15.3 2.4 6.3 10.4 22.0 19.1 21.8 16.6 14.5 10.3 18.4 10.0 14.2 9.3 14.6 14.4 9.5 32.1 13.6 7.5 25.7 13.2 7.1 0.3 12.7 20.6 0.9 1.2 23.7 14.8 7.3 15.5 19.9 14.5 15.2 19.5 12.2 22.4 14.0 10.4 8.7 12.5 19.3 39.8 6.3 5.0 11.1 15.5 8.4 31.9 6.5 16.0 9.6 23.2 10.6 11.5 21.9 21.4 17.2 22.7 9.9 12.6 14.2 16.8 12.5 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.5 26.2 0.0 19.9 15.2 5.4 0.2 5.0 0.4 0.9 14.2 6.6 4.1 6.4 13.0 8.5 1.2 3.3 0.7 1.0 0.6 8.2 1.8 1.5 1.8 0.0 5.6 9.2 87.6 3.5 0.6 1.1 0.0 0.2 72.8 2.4 2.1 2.7 1.8 12.8 147.0 0.8 4.8 2.2 3.1 3.6 1.3 10.5 1.1 0.7 3.6 0.0 139.8 4.4 6.1 3.7 0.8 44.1 1.2 2.0 3.6 7.5 0.0 15.4 1.0 82.4 18.7 0.2 0.1 1.2 4.1 0.4 0.8 7.5 1.7 15.2 0.0 0.6 3.3 33.2 4.2 7.7 1.3 1.0 2.2 4.3 4.4 1.0 CITED2 MRG1 ENSG00000164442 "Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2" Q99967 6 139371807-139374648 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Stress response, Transcription, Transcription regulation" "Activator, Developmental protein, Repressor" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 685.3;Plasma cells: 619.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 27.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 618.3;fHDF/TERT166: 1070.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016157, CAB069879" Supported Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "CAB016157: AB_668099, CAB069879: AB_10003446" "unprognostic (7.42e-2)" "unprognostic (2.06e-2)" "unprognostic (1.56e-2)" "unprognostic (8.34e-2)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (2.87e-2)" "unprognostic (1.13e-1)" "unprognostic (4.05e-2)" "unprognostic (1.11e-2)" "unprognostic (3.61e-3)" "unprognostic (1.00e-2)" "prognostic favorable (3.40e-4)" "prognostic unfavorable (3.33e-4)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" "unprognostic (2.03e-1)" 177.7 107.4 3.8 49.8 2.2 313.6 117.5 29.3 24.0 60.5 5.4 88.0 36.7 188.0 38.7 75.5 207.7 32.6 70.9 1.9 9.3 70.7 203.4 134.0 37.9 8.5 6.5 270.3 74.7 179.0 17.7 104.1 8.3 44.2 42.5 36.4 120.5 42.8 107.6 131.7 65.3 81.9 0.9 136.5 69.5 22.0 19.4 25.1 227.7 24.9 30.4 37.9 64.0 0.7 23.7 13.7 46.7 138.2 191.8 203.7 175.6 618.3 456.0 274.7 255.7 122.5 35.2 17.0 88.5 1070.3 58.5 28.0 14.2 14.5 192.4 467.0 45.8 346.9 76.0 10.1 157.1 103.1 36.5 164.6 64.4 121.3 91.4 177.9 51.2 10.1 132.9 80.1 359.2 51.0 17.5 128.3 43.8 15.0 21.2 24.7 34.2 152.3 131.7 52.5 51.8 0.8 45.2 167.6 21.2 106.8 72.3 348.3 283.6 219.9 69.5 66.4 35.0 23.4 22.6 26.3 68.0 86.9 15.8 3.1 8.2 27.7 3.4 4.6 5.0 1.2 5.4 4.9 3.6 3.1 4.7 2.4 4.0 3.0 6.6 1.6 3.6 3.3 3.8 2.2 29.3 24.0 1.9 9.3 8.5 6.5 8.3 0.9 19.4 0.7 157.1 115.4 272.8 3.6 138.8 35.8 111.5 12.7 347.8 30.6 164.4 180.0 114.1 80.1 36.5 103.0 12.5 173.1 156.5 159.6 185.9 20.5 1.5 122.6 131.7 68.9 99.7 274.3 6.9 14.9 685.3 200.3 121.8 262.3 46.9 133.9 61.1 65.5 372.6 30.3 22.2 111.6 20.3 124.4 67.7 7.7 99.4 188.9 83.6 9.4 44.2 51.9 55.6 1.0 1.3 23.1 97.7 60.9 619.4 46.6 88.8 121.0 27.4 52.5 98.6 107.9 179.1 1.8 20.8 200.8 33.8 269.3 291.8 272.9 112.6 38.4 CKAP2L "FLJ40629, radmis" ENSG00000169607 "Cytoskeleton associated protein 2 like" Q8IYA6 2 112736349-112764664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 13.1;lymphoid tissue: 12.1;testis: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Granulosa cells: 12.5;Spermatocytes: 33.0;Spermatogonia: 35.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039407, HPA040057, HPA070737" Uncertain Supported "Microtubules,Mitotic spindle,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Cytosol "HPA039407: AB_10794091, HPA040057: AB_10794871, HPA070737: AB_2686303" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (4.69e-3)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "unprognostic (5.59e-2)" "unprognostic (5.75e-5)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (9.57e-6)" "unprognostic (2.42e-1)" "unprognostic (0.00e+0)" "unprognostic (7.37e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" 0.4 0.1 0.2 2.6 0.2 13.1 0.4 0.4 0.3 0.4 0.0 1.6 1.5 0.3 0.1 2.3 0.1 0.3 0.0 0.2 0.1 0.1 0.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.2 0.2 0.3 0.0 0.0 1.5 1.1 1.1 0.0 0.9 1.0 4.5 0.2 12.1 0.2 0.0 5.2 0.8 0.6 0.2 47.9 9.6 35.4 16.2 2.0 3.3 7.2 38.5 32.2 37.9 36.1 8.7 13.3 32.0 15.5 15.1 48.3 18.0 20.4 19.6 64.1 44.8 8.9 53.6 12.7 7.7 0.1 25.2 30.9 0.9 1.9 47.4 27.2 10.1 17.5 22.8 14.3 44.9 31.2 6.9 31.0 10.6 15.4 20.0 29.5 22.3 37.0 8.4 6.9 18.7 19.7 12.7 15.2 12.8 13.3 13.2 12.4 11.8 12.9 42.7 33.7 34.5 28.5 9.9 20.1 26.6 18.5 18.1 69.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 3.2 0.6 0.0 1.2 3.3 2.1 2.7 0.6 0.0 0.5 0.8 0.5 1.5 0.4 0.0 0.0 11.1 1.3 1.3 0.0 0.4 2.4 1.1 1.6 1.1 0.0 25.2 0.3 0.4 10.6 2.0 1.5 2.1 0.0 12.5 2.9 0.1 6.6 0.0 0.2 3.1 2.0 1.9 1.4 2.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 5.6 1.1 0.1 0.1 0.4 0.0 0.0 0.4 2.8 33.0 35.7 9.5 1.7 1.0 2.5 0.7 3.8 1.1 CLCF1 "BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6" ENSG00000175505 "Cardiotrophin like cytokine factor 1" Q9UBD9 11 67364168-67374177 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 41.8;Glandular and luminal cells: 104.9;Pancreatic endocrine cells: 56.2;Prostatic glandular cells: 56.4;Urothelial cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SiHa: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA042444 Uncertain Approved "Nuclear bodies,Vesicles" "Secreted to blood" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" "Nuclear bodies, Vesicles" "HPA042444: AB_10794527" "unprognostic (2.68e-1)" "unprognostic (7.87e-3)" "unprognostic (6.21e-3)" "unprognostic (2.62e-2)" "prognostic unfavorable (9.91e-4)" "unprognostic (1.61e-2)" "unprognostic (1.09e-3)" "unprognostic (1.47e-2)" "unprognostic (5.08e-2)" "unprognostic (2.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.54e-1)" "unprognostic (1.67e-2)" "unprognostic (1.45e-2)" "unprognostic (1.10e-1)" "unprognostic (1.17e-2)" "unprognostic (2.37e-1)" 16.2 6.0 1.3 8.0 0.5 13.7 5.3 0.0 1.5 13.9 0.9 13.4 1.4 16.6 1.0 4.4 17.1 17.7 8.8 1.0 0.6 19.0 4.2 9.3 5.3 1.4 0.5 6.7 6.5 0.2 6.5 4.2 0.4 7.2 1.7 1.4 9.1 1.8 1.5 2.6 9.4 8.3 0.0 8.1 11.2 1.9 2.1 0.7 9.7 1.9 4.4 18.1 7.6 0.2 15.1 31.4 2.2 9.7 4.2 5.8 0.0 20.9 11.6 14.4 7.0 5.1 40.3 9.1 17.1 26.8 17.5 10.3 0.4 10.7 6.3 0.5 0.3 0.1 23.9 4.0 13.6 1.9 2.4 7.6 2.6 15.0 6.5 27.4 3.1 0.0 3.5 0.4 15.0 12.0 0.1 6.8 8.1 18.9 28.8 0.9 4.8 0.5 22.7 0.8 0.1 1.6 57.8 2.2 1.3 4.4 1.3 2.5 12.5 27.6 11.6 35.4 31.5 2.0 0.1 1.0 35.4 1.8 11.1 0.0 0.9 15.2 10.5 3.4 6.2 10.8 4.8 8.3 1.3 13.8 0.1 3.5 0.3 0.2 10.5 0.0 1.1 3.2 1.3 0.5 0.0 1.5 1.0 0.6 1.4 0.5 0.4 0.0 2.1 0.2 4.2 16.0 4.8 1.3 10.6 3.7 25.9 6.5 1.8 0.0 14.5 2.4 0.8 25.8 9.6 7.3 0.0 0.4 10.0 3.8 1.9 24.0 1.8 41.8 19.4 6.2 1.2 0.0 0.7 11.8 0.6 14.0 5.1 104.9 3.8 2.1 2.9 1.0 1.2 0.0 0.5 2.3 6.1 0.3 10.7 4.7 3.4 6.7 8.8 1.0 6.5 1.7 3.1 0.5 0.1 56.2 14.3 0.0 9.5 56.4 0.2 5.2 1.7 0.3 0.0 32.6 10.4 0.3 0.9 1.6 4.4 0.1 9.7 0.1 1.5 65.2 CLCN7 "CLC-7, CLC7, OPTA2, PPP1R63" ENSG00000103249 "Chloride voltage-gated channel 7" P51798 16 1444934-1475084 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 74.0" "Cancer enhanced" "Detected in all" "melanoma: 42.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043019, HPA043586" Supported NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "HPA043019: AB_10964727, HPA043586: AB_10965322" "unprognostic (2.69e-1)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (5.61e-2)" "unprognostic (1.90e-2)" "prognostic favorable (5.23e-4)" "unprognostic (1.59e-2)" "unprognostic (1.29e-2)" "unprognostic (1.17e-1)" "unprognostic (4.65e-2)" "unprognostic (1.41e-2)" "unprognostic (3.98e-1)" "unprognostic (3.49e-3)" "unprognostic (5.81e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (2.80e-1)" "unprognostic (2.54e-1)" 18.1 37.3 14.4 16.9 14.2 34.3 17.3 12.8 18.0 18.7 18.0 20.0 16.6 20.3 6.3 12.4 17.0 12.3 16.6 14.2 14.1 21.1 22.0 19.1 18.3 17.9 19.2 15.1 21.8 20.8 21.7 12.4 20.7 16.5 7.1 9.2 16.8 12.0 28.0 23.1 22.7 13.2 11.9 27.3 22.3 19.2 18.0 15.6 23.1 8.3 12.1 16.0 11.9 15.8 14.2 36.9 21.0 33.7 41.3 21.5 34.3 18.9 36.4 35.2 41.5 30.8 51.2 16.3 38.6 23.7 73.8 29.4 18.4 21.0 11.4 26.1 31.5 11.6 37.9 30.0 72.4 29.4 45.1 42.9 28.4 32.1 28.5 23.9 23.0 36.3 48.0 29.2 18.5 28.4 21.3 50.6 21.7 9.0 21.8 96.7 13.3 45.2 16.4 18.2 22.5 24.9 30.8 37.5 120.2 11.8 33.6 78.0 26.3 34.9 16.2 39.1 18.4 47.3 32.1 16.5 28.2 54.3 22.6 0.0 1.6 1.2 0.8 2.7 0.3 1.0 0.4 0.4 1.2 1.0 0.2 0.3 0.3 0.3 3.4 1.1 0.1 1.0 14.4 14.2 12.8 18.0 14.2 14.1 17.9 19.2 20.7 11.9 18.0 15.8 12.6 0.0 7.5 25.1 16.5 7.4 5.5 6.3 9.1 45.0 14.5 12.7 4.4 4.3 8.2 20.2 35.5 10.2 12.3 20.4 1.9 16.2 10.2 14.0 14.9 11.1 12.0 8.0 22.3 17.8 8.9 11.0 18.8 17.9 6.3 24.0 16.8 15.6 36.3 74.0 20.6 14.5 4.1 28.3 11.5 8.6 11.5 29.6 39.2 24.4 22.4 27.3 13.4 8.5 17.9 17.9 7.3 8.2 9.3 9.0 14.5 14.7 7.8 28.1 0.0 9.9 11.9 13.5 10.7 5.6 6.8 15.5 9.4 19.4 15.1 5.2 CLDN1 "ILVASC, SEMP1" ENSG00000163347 "Claudin 1" O95832 3 190305707-190322446 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 309.8;skin 1: 288.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 440.1;Basal prostatic cells: 291.1;Prostatic glandular cells: 501.6;Squamous epithelial cells: 298.2;Suprabasal keratinocytes: 836.1;Urothelial cells: 562.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "EFO-21: 658.6;HaCaT: 236.5;hTCEpi: 288.6;RPTEC TERT1: 414.9;RT4: 267.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 12 "spinal cord: 25.4" "CAB002602, HPA048319" Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "CAB002602: , HPA048319: AB_2680355" "unprognostic (5.89e-2)" "unprognostic (4.58e-3)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (7.92e-3)" "unprognostic (2.43e-1)" "unprognostic (3.54e-1)" "unprognostic (2.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (5.23e-4)" "unprognostic (3.06e-1)" "unprognostic (1.13e-1)" "unprognostic (4.43e-2)" "unprognostic (9.20e-2)" "unprognostic (1.09e-3)" "unprognostic (1.22e-1)" 40.8 47.9 1.5 1.2 1.1 0.2 22.7 0.8 1.3 17.7 20.7 1.7 1.1 64.2 31.9 40.9 56.6 15.5 2.5 1.5 1.2 10.5 309.8 9.1 0.5 1.2 2.8 6.3 34.3 0.4 2.4 5.3 1.7 13.6 1.6 0.9 34.0 46.0 1.1 288.2 0.7 126.6 0.7 1.5 1.0 4.3 1.1 9.4 36.2 4.9 44.2 40.4 35.9 1.0 34.0 29.7 0.2 0.1 0.0 0.1 0.0 2.5 52.7 1.1 2.1 17.7 69.1 0.0 658.6 0.3 58.5 236.5 1.5 77.7 6.2 0.9 1.4 0.1 9.3 41.5 49.6 0.4 0.2 0.5 288.6 6.0 87.0 2.4 0.6 0.0 0.1 0.1 0.1 6.5 0.1 0.1 1.5 2.3 5.5 0.0 0.6 0.2 414.9 267.0 0.2 0.0 31.0 5.7 18.4 3.5 53.5 0.5 12.9 0.6 9.9 0.2 1.4 0.7 0.6 1.2 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.8 1.3 1.5 1.2 1.2 2.8 1.7 0.7 1.1 1.0 0.4 12.8 34.7 0.0 0.5 440.1 291.1 217.3 84.2 0.0 35.6 2.0 1.0 170.1 143.2 31.3 0.0 2.4 0.6 0.6 0.0 203.3 0.1 44.4 10.0 7.0 1.8 0.0 0.7 56.3 0.3 29.2 2.0 100.0 1.3 0.4 1.4 188.2 1.0 0.0 1.6 0.3 54.9 3.8 66.5 1.7 15.5 8.5 32.0 0.0 5.7 0.0 0.0 24.6 0.0 139.9 0.0 35.3 0.0 501.6 0.1 4.1 144.6 0.0 0.0 0.3 11.2 0.3 0.8 298.2 836.1 33.8 2.6 5.0 1.0 562.9 CLMP "ACAM, ASAM, FLJ22415" ENSG00000166250 "CXADR like membrane protein" Q9H6B4 11 123069872-123195248 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 63.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 75.7;Fibroblasts: 95.1;Inhibitory neurons: 31.9;Peritubular cells: 57.9;Skeletal myocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 124.8;BJ: 171.8;BJ hTERT+: 160.3;fHDF/TERT166: 126.6;hTEC/SVTERT24-B: 129.1;hTERT-HME1: 155.6;U-138 MG: 232.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.63e-2)" "unprognostic (6.65e-3)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (3.46e-2)" "unprognostic (9.42e-3)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (9.66e-3)" "unprognostic (3.25e-2)" "unprognostic (4.02e-3)" "unprognostic (3.87e-2)" "unprognostic (9.78e-8)" "unprognostic (3.88e-3)" "unprognostic (1.26e-1)" "unprognostic (1.19e-2)" "unprognostic (1.69e-2)" 63.2 6.5 0.9 14.7 0.8 0.4 24.5 7.8 2.7 20.5 3.6 41.1 7.3 30.3 4.3 10.1 18.4 23.1 12.9 5.3 0.4 6.0 0.4 8.1 7.4 4.2 2.1 9.1 2.0 0.2 1.9 26.3 1.8 7.4 10.6 0.9 5.4 8.5 1.7 6.5 17.3 36.3 2.0 8.1 16.0 2.6 2.1 0.8 2.4 3.4 5.0 16.7 14.0 5.2 3.0 3.3 7.5 15.2 124.8 108.1 45.5 171.8 160.3 23.9 43.8 7.4 0.2 0.0 0.4 126.6 82.4 0.1 0.3 45.5 27.3 0.9 0.3 0.0 7.1 0.1 40.7 0.0 0.1 61.0 30.6 129.1 155.6 59.7 11.7 0.1 0.0 0.4 33.3 0.1 0.0 0.2 17.4 0.0 20.2 0.1 2.5 0.1 12.6 0.0 20.5 50.3 0.0 0.4 0.1 3.2 0.6 0.0 43.3 232.7 2.3 96.0 21.6 0.1 0.0 0.1 63.1 0.0 7.5 0.3 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.9 0.8 7.8 2.7 5.3 0.4 4.2 2.1 1.8 2.0 2.1 5.2 2.3 0.0 3.9 2.0 0.2 1.5 0.3 2.4 0.0 3.8 1.2 14.6 5.1 0.0 0.4 0.0 0.0 9.8 0.3 0.1 0.0 1.9 0.7 2.4 75.7 1.4 6.7 0.0 26.5 1.3 20.4 95.1 0.0 1.4 0.0 5.3 2.2 0.0 3.6 1.7 31.9 0.5 0.0 0.0 1.9 0.7 20.8 0.9 0.0 4.7 0.0 0.5 0.0 1.0 3.6 0.9 0.0 57.9 0.6 2.0 0.1 0.1 0.2 1.1 0.0 65.0 8.5 0.1 0.1 0.4 1.0 10.4 1.1 2.2 0.3 0.5 CLP1 "hClp1, HEAB" ENSG00000172409 "Cleavage factor polyribonucleotide kinase subunit 1" Q92989 11 57648188-57661865 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" "Kinase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 32.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057770 Supported Supported Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA057770: AB_2683523" "unprognostic (1.33e-1)" "unprognostic (7.90e-2)" "unprognostic (1.11e-3)" "unprognostic (2.13e-2)" "unprognostic (4.90e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-3)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (1.66e-2)" "unprognostic (8.82e-2)" "unprognostic (7.58e-2)" "unprognostic (8.31e-3)" "unprognostic (3.71e-2)" "unprognostic (1.75e-1)" "unprognostic (8.78e-2)" "unprognostic (3.07e-1)" 8.9 7.4 3.1 10.1 3.6 26.1 9.2 3.9 4.4 7.1 4.4 9.0 8.7 7.7 7.6 9.2 7.3 5.9 6.5 3.3 3.3 8.0 10.1 7.3 10.8 3.3 3.1 6.8 7.4 6.8 4.4 9.2 3.7 5.6 8.6 3.2 6.7 7.1 8.2 9.0 8.4 8.9 3.4 10.0 8.1 8.4 3.3 11.2 7.2 9.3 13.1 8.6 5.0 3.7 21.2 22.2 21.0 21.6 22.3 14.4 19.7 21.4 23.2 30.1 25.8 21.4 18.4 35.1 24.3 18.9 24.2 25.9 29.2 34.5 34.2 24.3 18.0 19.4 13.5 21.7 17.7 28.5 22.2 17.4 24.0 26.9 18.6 11.9 27.7 17.4 30.4 11.9 24.9 14.8 21.8 32.9 31.8 24.3 22.2 21.7 32.1 37.5 16.5 15.0 11.1 22.3 19.1 17.2 28.7 21.7 32.7 23.2 20.0 16.0 21.7 27.7 15.9 18.6 26.4 39.3 17.3 16.3 17.3 31.2 19.0 20.0 15.9 16.4 18.9 15.6 14.1 16.4 19.0 14.3 16.4 14.9 21.7 13.6 15.9 10.8 16.2 12.3 3.1 3.6 3.9 4.4 3.3 3.3 3.3 3.1 3.7 3.4 3.3 3.7 6.1 9.6 5.1 1.0 8.5 19.4 10.7 13.4 16.5 4.3 6.0 6.2 2.4 7.2 10.5 0.0 6.2 16.5 12.7 4.8 9.8 12.9 32.5 6.7 5.7 7.3 2.4 12.2 1.9 11.7 13.9 7.4 3.1 7.1 8.2 4.9 4.2 3.5 11.0 5.0 1.8 3.2 8.2 6.0 6.9 4.1 5.6 5.8 8.8 1.0 15.0 3.3 7.2 2.5 1.4 9.8 4.7 8.6 5.9 4.7 6.2 10.1 6.4 3.1 6.6 10.4 6.9 9.4 12.0 9.3 14.5 13.5 9.7 6.5 4.6 7.8 CLPP ENSG00000125656 "Caseinolytic mitochondrial matrix peptidase proteolytic subunit" Q16740 19 6361531-6370242 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010649 Supported Supported Mitochondria NA NA 8500 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA010649: AB_1078538" "unprognostic (2.28e-1)" "unprognostic (7.14e-2)" "unprognostic (2.82e-1)" "unprognostic (4.34e-2)" "unprognostic (2.17e-2)" "unprognostic (1.15e-2)" "unprognostic (6.17e-3)" "unprognostic (7.43e-2)" "unprognostic (2.76e-1)" "unprognostic (1.31e-1)" "prognostic favorable (6.50e-4)" "unprognostic (1.21e-1)" "unprognostic (5.65e-2)" "unprognostic (6.97e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.86e-3)" 48.6 65.8 52.0 41.5 51.5 42.9 45.1 52.2 63.8 39.1 58.0 46.6 47.4 41.1 17.8 56.1 40.1 20.8 78.0 50.9 52.7 60.5 90.7 39.7 47.7 52.8 52.4 38.5 53.6 36.6 44.5 25.4 49.5 41.0 22.9 15.6 48.3 31.2 146.8 47.5 43.6 25.1 51.8 45.6 55.6 45.2 54.5 45.2 36.1 59.3 35.6 44.6 37.9 53.9 146.7 98.2 61.2 113.9 38.7 54.8 62.4 76.9 59.5 112.2 102.5 87.2 48.9 124.1 122.8 61.3 61.1 83.1 63.5 109.1 38.5 133.8 189.3 95.8 82.2 122.9 106.6 90.7 129.8 73.4 74.4 78.9 82.9 69.7 113.9 188.5 97.5 174.5 72.3 192.8 153.1 104.5 93.2 100.6 207.8 108.6 73.2 206.2 81.2 79.4 99.3 95.9 48.9 123.8 133.0 36.7 67.3 130.6 76.9 70.5 69.7 180.7 156.0 235.4 225.3 137.2 103.5 132.9 117.3 29.4 82.6 47.8 112.0 79.6 133.5 119.5 159.4 139.6 102.4 131.5 138.4 137.4 62.1 126.5 55.5 155.5 207.2 162.6 52.0 51.5 52.2 63.8 50.9 52.7 52.8 52.4 49.5 51.8 54.5 53.9 39.6 22.4 35.2 8.1 45.9 44.9 59.5 90.8 38.1 31.0 47.6 57.9 45.8 55.8 46.2 44.1 12.5 72.2 43.7 56.0 144.8 88.8 105.5 27.6 43.1 51.6 35.3 54.9 5.4 96.6 113.6 42.4 36.2 35.0 26.0 63.1 61.8 89.6 81.3 21.9 7.5 50.9 54.9 38.9 35.0 229.8 42.6 38.7 55.2 4.7 70.6 46.6 46.4 4.5 9.5 101.9 67.7 43.2 82.4 89.5 110.9 189.0 44.5 24.6 13.1 30.0 79.9 67.7 48.1 56.5 37.1 57.7 65.3 95.1 65.4 65.4 CNOT1 "AD-005, CDC39, KIAA1007, NOT1, NOT1H" ENSG00000125107 "CCR4-NOT transcription complex subunit 1" A5YKK6 16 58519951-58629885 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Autism spectrum disorder, Disease variant, Holoprosencephaly, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046577, HPA049664" Approved Supported Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA046577: AB_2679706, HPA049664: AB_2680844" "unprognostic (1.30e-2)" "unprognostic (6.86e-2)" "unprognostic (9.25e-3)" "unprognostic (1.66e-1)" "unprognostic (2.39e-2)" "unprognostic (7.11e-2)" "unprognostic (3.58e-2)" "unprognostic (2.19e-1)" "unprognostic (6.43e-2)" "unprognostic (6.99e-2)" "unprognostic (1.83e-2)" "unprognostic (6.63e-2)" "unprognostic (1.33e-3)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (5.53e-2)" "unprognostic (1.52e-1)" 29.8 35.2 8.4 46.9 10.7 45.6 36.3 17.4 11.5 34.7 33.5 60.1 55.0 31.8 27.6 73.1 38.9 28.3 26.3 8.6 9.4 39.8 36.0 33.3 58.1 11.5 10.5 39.2 41.1 59.7 21.2 35.1 11.3 31.2 57.3 32.4 38.8 30.6 52.4 43.1 52.3 33.7 8.9 42.9 42.1 108.2 10.6 76.4 42.4 44.1 69.5 49.1 38.6 15.2 128.8 148.2 110.0 88.1 52.1 66.2 127.6 99.6 85.8 111.4 82.0 167.6 75.3 194.0 47.4 75.8 65.5 122.3 177.9 101.0 149.2 72.5 98.8 150.4 121.8 193.7 70.8 235.8 162.4 64.0 67.5 129.7 151.5 66.9 87.7 107.2 181.0 55.3 76.4 52.0 182.6 61.2 114.4 84.9 127.2 229.0 189.5 122.7 62.4 180.0 90.9 58.6 336.0 113.5 56.0 100.5 67.9 121.3 100.9 81.3 80.0 62.2 88.7 124.7 138.2 390.3 85.5 99.4 76.9 18.3 12.1 13.4 13.8 15.6 18.2 14.7 12.9 14.0 14.6 13.8 12.1 12.6 18.6 15.4 22.5 7.3 15.4 11.5 8.4 10.7 17.4 11.5 8.6 9.4 11.5 10.5 11.3 8.9 10.6 15.2 44.4 16.0 42.9 33.0 57.8 47.4 32.6 42.9 25.6 28.2 33.9 27.9 23.8 37.1 45.2 23.9 29.2 33.7 86.3 64.5 9.8 29.8 107.7 57.6 48.0 31.3 36.1 45.0 31.7 47.0 29.9 30.7 35.2 78.2 32.2 45.9 23.9 42.3 35.7 40.4 35.6 54.2 24.4 51.5 39.5 38.6 24.8 46.4 19.6 42.2 50.0 20.0 34.0 42.3 54.9 42.5 34.9 32.4 59.8 43.6 60.1 22.9 51.6 24.3 32.9 38.7 30.4 136.6 64.3 56.0 47.0 37.9 52.1 27.9 64.5 61.2 CNTNAP1 "Caspr, CNTNAP, NRXN4, p190" ENSG00000108797 "Contactin associated protein 1" P78357 17 42682531-42699993 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.7" "Cell type enhanced" "Detected in many" "Astrocytes: 11.4;Bipolar cells: 15.6;Endometrial stromal cells: 15.5;Excitatory neurons: 45.6;Inhibitory neurons: 37.7" "Cancer enhanced" "Detected in all" "glioma: 10.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 43.5;TIME: 68.5;U-138 MG: 76.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011772 Approved Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA011772: AB_1079541" "unprognostic (4.04e-2)" "unprognostic (3.69e-1)" "unprognostic (2.37e-3)" "unprognostic (1.89e-1)" "unprognostic (5.02e-3)" "unprognostic (1.13e-1)" "unprognostic (3.19e-3)" "unprognostic (1.19e-1)" "unprognostic (2.59e-1)" "unprognostic (9.76e-3)" "unprognostic (1.99e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.16e-14)" "unprognostic (9.52e-3)" "unprognostic (2.27e-2)" "unprognostic (3.11e-2)" "unprognostic (7.37e-3)" 7.1 3.6 27.5 5.6 30.8 0.6 5.0 13.5 46.7 12.0 0.0 23.8 1.8 21.8 6.1 2.2 14.0 6.3 8.2 29.5 15.7 6.4 1.5 6.9 2.4 21.6 15.4 15.7 11.5 0.6 19.3 4.5 19.1 7.2 3.9 11.3 2.9 6.5 3.7 2.2 6.0 25.9 8.1 4.9 9.8 3.3 18.8 1.2 4.9 2.5 2.4 8.0 8.5 29.4 4.1 5.4 13.2 4.2 20.0 40.4 0.8 25.6 43.5 18.2 16.5 0.5 1.0 0.1 1.3 27.7 18.6 4.8 6.4 2.0 14.2 9.0 2.1 0.0 24.0 6.4 9.8 0.2 0.4 39.7 0.1 17.5 3.5 29.1 23.3 0.2 1.2 7.6 7.1 0.7 0.1 3.8 4.7 0.3 5.5 0.7 1.4 2.0 4.8 0.0 2.4 7.7 7.6 0.1 4.7 12.0 4.1 2.3 68.5 76.2 12.5 18.0 7.0 8.5 5.7 0.2 21.4 1.7 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 27.5 30.8 13.5 46.7 29.5 15.7 21.6 15.4 19.1 8.1 18.8 29.4 1.0 0.0 4.1 11.4 0.5 0.5 0.2 0.4 1.2 15.6 0.2 0.1 1.3 0.0 0.7 0.0 4.2 0.0 0.1 0.1 0.0 0.0 0.9 3.2 15.5 1.2 0.0 0.0 45.6 0.0 0.0 4.2 0.5 1.0 0.0 0.1 1.8 0.0 0.1 1.7 37.7 0.1 0.0 0.0 0.8 0.3 1.5 0.2 0.0 6.5 0.8 0.9 0.0 7.5 5.2 0.1 0.1 0.7 0.4 0.3 0.0 0.1 1.6 3.0 6.6 1.1 6.3 1.4 1.1 0.3 0.3 0.3 0.6 0.2 0.1 0.2 CNTNAP2 "Caspr2, KIAA0868, NRXN4" ENSG00000174469 "Contactin associated protein 2" Q9UHC6 7 146116002-148420998 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Autism, Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 20.7;retina: 14.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 3383.0;Inhibitory neurons: 6845.7" "Cancer enhanced" "Detected in many" "prostate cancer: 10.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 25 "B-cells: 2.5" "Cell line enhanced" "Detected in some" "AF22: 8.0;CACO-2: 6.7;NTERA-2: 12.0;SCLC-21H: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002739 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA002739: AB_1078545" "unprognostic (2.49e-2)" "unprognostic (1.49e-2)" "unprognostic (4.05e-1)" "unprognostic (3.08e-3)" "unprognostic (1.77e-1)" "unprognostic (2.29e-1)" "unprognostic (2.51e-2)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (3.67e-2)" "unprognostic (2.68e-1)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (1.00e-3)" 0.2 0.8 10.0 0.2 13.8 0.0 0.6 1.4 20.7 0.1 0.0 0.8 0.0 0.0 0.0 0.4 0.6 0.0 0.2 5.6 5.7 0.1 1.9 0.0 0.4 5.7 0.5 1.1 0.2 0.3 3.8 0.5 3.8 4.1 0.4 14.4 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.4 0.2 0.5 1.8 3.7 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 8.0 3.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 6.7 0.1 0.0 0.0 0.2 0.0 2.0 1.7 0.6 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.0 1.4 0.0 0.0 0.0 2.2 0.0 0.0 21.5 1.4 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.0 13.8 1.4 20.7 5.6 5.7 5.7 0.5 3.8 0.0 1.8 0.0 0.1 0.0 0.0 65.6 9.3 0.1 0.3 15.5 1.8 33.9 0.3 0.0 1.2 7.2 4.1 0.0 2.1 40.8 0.0 1.8 0.0 1.4 7.2 0.6 0.0 0.6 2.4 0.0 3383.0 0.7 6.8 1.1 0.5 0.7 0.0 0.2 0.0 8.9 3.3 1031.4 6845.7 3.9 0.0 0.6 2.0 2.7 1.2 0.4 0.0 180.8 0.2 8.2 1.0 429.3 914.7 4.1 2.1 0.0 0.3 7.4 4.7 0.5 0.9 16.7 0.0 0.0 0.9 2.4 12.0 9.1 0.0 6.3 0.0 1.2 6.8 0.2 COL10A1 ENSG00000123500 "Collagen type X alpha 1 chain" Q03692 6 116118909-116158747 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.5;choroid plexus: 39.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 26.6;Inhibitory neurons: 6.3;Microglial cells: 8.4;Oligodendrocytes: 27.9" "Cancer enhanced" "Detected in many" "breast cancer: 42.8;pancreatic cancer: 51.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTEC/SVTERT24-B: 39.7" "Low region specificity" "Detected in many" HPA053268 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA053268: " "unprognostic (3.83e-2)" "unprognostic (6.81e-2)" "unprognostic (7.20e-2)" "unprognostic (7.45e-3)" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (3.84e-2)" "unprognostic (1.49e-1)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" "unprognostic (4.37e-2)" "unprognostic (7.03e-2)" "unprognostic (1.38e-11)" "unprognostic (2.16e-3)" "unprognostic (7.22e-2)" "unprognostic (3.60e-1)" "unprognostic (2.06e-3)" 0.3 0.0 2.2 0.2 8.6 0.3 0.3 4.6 4.5 1.2 39.9 0.2 0.0 0.3 0.0 0.0 0.0 8.9 0.3 1.3 3.3 0.4 0.2 2.8 0.6 7.7 5.6 3.9 3.3 2.5 0.4 0.1 7.1 1.9 0.1 0.9 2.6 0.8 0.1 0.4 0.1 0.5 4.3 2.5 0.1 0.2 6.3 0.1 0.7 0.0 1.9 0.2 0.1 15.5 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.2 2.9 0.4 6.0 0.1 0.0 0.1 0.0 1.0 0.0 0.7 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.8 0.0 39.7 0.0 0.2 0.0 0.1 0.2 0.0 0.3 0.0 0.3 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.2 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.0 6.3 0.1 0.4 0.5 0.0 0.0 0.1 0.6 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 8.6 4.6 4.5 1.3 3.3 7.7 5.6 7.1 4.3 6.3 15.5 2.6 0.0 0.6 3.9 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.1 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.4 26.6 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 6.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.4 0.0 2.2 0.0 2.5 27.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.2 5.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 COL11A1 "CO11A1, COLL6, DFNA37, STL2" ENSG00000060718 "Collagen type XI alpha 1 chain" P12107 1 102876467-103108872 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 20.1;retina: 9.6" "Cell type enhanced" "Detected in some" "Astrocytes: 83.9;Excitatory neurons: 99.5;Oligodendrocyte precursor cells: 557.4;Theca cells: 139.6" "Cancer enhanced" "Detected in many" "breast cancer: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 116.9;BJ: 43.2;BJ hTERT+ SV40 Large T+ RasG12V: 85.3;HBF TERT88: 48.7;HSkMC: 142.5;SuSa: 60.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058335 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 640000 "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Endoplasmic reticulum" "HPA058335: AB_2683682" "unprognostic (2.60e-3)" "unprognostic (6.61e-4)" "unprognostic (9.58e-2)" "unprognostic (5.06e-5)" "unprognostic (2.83e-1)" "unprognostic (2.85e-2)" "unprognostic (6.03e-3)" "unprognostic (2.23e-3)" "unprognostic (9.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-2)" "unprognostic (1.94e-2)" "unprognostic (3.01e-12)" "unprognostic (1.27e-2)" "unprognostic (3.53e-1)" "unprognostic (3.54e-2)" "unprognostic (2.32e-2)" 0.6 0.6 4.3 0.3 3.1 0.0 0.4 1.6 4.6 0.9 2.8 0.4 0.1 0.5 0.1 0.0 0.0 3.1 0.0 2.4 2.5 0.1 0.0 0.3 0.1 2.5 3.7 0.6 0.7 0.2 3.3 20.1 2.2 0.2 0.3 9.6 1.5 0.8 0.1 1.4 0.1 0.3 1.0 0.5 0.1 1.4 2.2 0.0 0.1 0.1 0.0 0.2 0.1 2.1 0.0 0.8 116.9 0.0 4.6 5.9 0.0 43.2 16.1 23.3 85.3 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 142.5 0.0 1.1 0.0 17.7 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.0 8.1 0.0 0.1 0.0 7.4 0.0 15.2 0.0 0.1 0.0 0.0 0.1 0.0 60.5 0.0 0.1 0.0 0.6 27.0 0.0 4.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 3.1 1.6 4.6 2.4 2.5 2.5 3.7 2.2 1.0 2.2 2.1 0.0 0.0 2.2 83.9 0.0 1.8 0.0 0.0 0.0 9.4 0.1 4.2 0.5 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 21.0 0.1 0.9 2.2 0.0 0.0 99.5 0.0 0.8 18.7 0.0 0.0 2.5 8.3 0.0 0.0 0.3 0.0 32.9 0.0 0.0 0.0 1.3 4.0 1.2 0.2 10.6 29.0 0.0 29.8 0.0 557.4 6.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.9 2.6 0.5 0.8 0.0 1.1 0.3 0.2 139.6 0.0 0.0 COL11A2 "DFNA13, DFNB53, HKE5" ENSG00000204248 "Collagen type XI alpha 2 chain" P13942 6 33162681-33192499 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "pituitary gland: 23.5;testis: 8.1" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Early spermatids: 10.8;Muller glia cells: 5.2;Oligodendrocytes: 6.7" "Cancer enriched" "Detected in many" 8 "melanoma: 13.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 2100000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (4.62e-1)" "unprognostic (8.69e-2)" "unprognostic (1.65e-4)" "unprognostic (5.15e-3)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (1.04e-2)" "unprognostic (9.67e-2)" "unprognostic (2.05e-2)" "unprognostic (4.47e-2)" "unprognostic (1.22e-1)" "unprognostic (3.41e-3)" "unprognostic (2.26e-6)" "unprognostic (8.27e-2)" "unprognostic (2.17e-1)" "unprognostic (1.88e-1)" "unprognostic (5.96e-2)" 1.0 0.3 0.3 0.0 0.6 0.0 0.9 0.5 0.6 1.6 0.0 0.7 0.2 1.2 0.2 0.5 0.9 0.1 1.8 0.3 0.3 1.3 0.8 1.0 0.0 0.5 0.4 1.1 0.6 0.1 23.5 0.0 0.5 1.3 0.0 0.1 0.8 0.1 1.3 0.6 0.7 0.1 0.5 1.2 0.7 8.1 0.5 0.3 3.5 0.7 0.0 0.6 0.9 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.2 0.2 0.0 0.0 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.5 0.6 0.3 0.3 0.5 0.4 0.5 0.5 0.5 0.8 2.6 0.0 0.0 8.5 0.1 1.5 0.2 0.1 1.8 2.8 1.2 1.8 2.3 0.0 0.1 0.0 4.2 0.0 0.6 0.3 0.0 0.1 10.8 0.2 0.6 1.5 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.5 0.0 0.6 4.6 0.2 0.2 0.0 3.7 0.1 0.0 0.6 0.4 1.9 0.0 0.3 1.8 1.0 0.0 5.2 0.0 3.5 6.7 0.1 0.6 0.4 0.8 0.2 0.0 0.1 0.0 1.1 0.0 0.7 1.8 0.9 2.1 0.7 1.1 0.0 0.4 0.2 0.5 0.1 COL12A1 COL12A1L ENSG00000111799 "Collagen type XII alpha 1 chain" Q99715 6 75084326-75206267 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Endometrial stromal cells: 44.3;Excitatory neurons: 52.9;Fibroblasts: 99.7;Leydig cells: 60.3;Sertoli cells: 46.0;Smooth muscle cells: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "fHDF/TERT166: 1432.1;SiHa: 846.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 29.1" "HPA009143, HPA010021" Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 9100000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "HPA009143: AB_1847095, HPA010021: " "unprognostic (2.60e-2)" "unprognostic (2.80e-3)" "unprognostic (7.92e-2)" "unprognostic (8.27e-3)" "unprognostic (1.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (3.47e-3)" "unprognostic (1.38e-1)" "unprognostic (4.30e-1)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "prognostic unfavorable (1.69e-9)" "unprognostic (1.03e-3)" "unprognostic (1.81e-1)" "unprognostic (3.16e-3)" "unprognostic (1.92e-2)" 105.1 15.7 2.2 16.0 1.9 0.0 65.4 0.8 2.7 112.8 0.4 74.9 8.7 124.5 5.5 36.2 42.2 20.9 25.5 1.0 1.2 25.9 3.5 24.6 7.2 1.8 4.8 123.2 5.9 5.0 4.8 1.8 0.6 20.8 17.2 0.4 16.1 42.4 14.4 48.9 40.6 72.1 0.6 11.4 18.1 4.6 2.0 5.5 19.3 12.5 4.2 26.3 45.8 0.8 0.2 2.2 11.5 0.2 270.2 162.0 28.3 275.4 229.3 186.2 257.3 27.5 0.7 0.0 27.7 1432.1 3.9 59.2 0.5 28.7 174.6 0.2 1.4 0.2 101.1 0.1 97.9 0.3 0.2 234.9 5.0 42.2 50.6 173.6 32.0 0.1 0.0 0.0 29.4 0.2 0.1 0.2 6.4 0.0 15.3 0.1 23.1 0.2 8.9 14.4 0.0 0.0 846.1 21.2 0.3 15.5 131.8 0.5 0.2 78.5 97.0 41.5 91.4 0.1 0.1 0.4 26.4 0.3 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 0.8 2.7 1.0 1.2 1.8 4.8 0.6 0.6 2.0 0.8 14.2 76.9 5.1 2.3 0.0 20.6 0.6 12.7 5.2 0.4 4.7 7.1 4.1 0.0 4.7 3.7 0.0 0.6 0.0 0.0 0.0 1.4 24.1 6.3 44.3 11.0 0.0 0.0 52.9 4.6 1.3 99.7 2.6 14.1 1.3 0.1 3.3 0.0 0.8 0.0 32.4 0.0 0.0 0.3 18.4 14.7 60.3 1.8 21.4 38.4 0.0 0.0 0.0 19.6 1.2 6.7 0.0 13.2 0.1 1.7 0.0 0.9 1.7 0.0 46.0 20.0 48.6 0.3 0.6 0.6 13.1 0.7 2.5 1.4 0.1 0.3 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 479.6;Sertoli cells: 223.5;Smooth muscle cells: 268.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 139.0;EFO-21: 309.4;NTERA-2: 170.6;RPTEC TERT1: 131.6;TIME: 186.0" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 290000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA030933: , HPA036104: AB_2674943" "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" 136.4 87.6 14.5 33.9 22.3 15.9 97.1 26.4 21.8 229.4 34.4 91.2 30.4 135.6 35.4 50.1 118.3 28.9 122.2 15.7 18.1 218.2 561.9 83.2 19.8 43.7 28.6 257.3 102.3 7.9 106.5 40.7 39.1 91.0 5.5 5.4 35.8 46.8 26.5 77.8 65.7 28.5 26.6 86.8 44.5 30.0 27.0 9.0 101.1 7.4 7.2 109.8 112.2 45.4 10.5 84.0 20.6 18.0 38.6 31.9 3.3 82.0 139.0 39.1 10.5 48.8 28.9 1.5 309.4 82.8 21.6 37.9 4.6 5.0 7.4 0.7 20.0 47.9 1.4 69.6 37.3 0.7 4.4 37.6 3.3 3.8 4.5 8.5 121.3 0.5 49.6 0.3 14.4 16.7 0.8 3.2 170.6 3.2 30.7 0.7 12.6 4.0 131.6 1.3 22.8 16.3 7.6 7.8 26.6 73.0 7.5 9.9 186.0 0.5 11.4 0.4 17.7 0.4 0.8 1.5 0.1 1.7 32.7 0.8 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.2 3.2 0.0 0.0 0.1 0.0 0.1 14.5 22.3 26.4 21.8 15.7 18.1 43.7 28.6 39.1 26.6 27.0 45.4 156.9 0.0 4.1 6.5 3.9 67.7 15.5 19.0 67.7 13.5 9.3 32.1 15.7 61.5 5.0 112.2 4.2 1.9 3.4 0.1 9.8 117.5 1.5 58.3 99.5 91.2 0.0 33.0 4.9 5.8 1.1 101.1 3.6 144.2 57.8 6.6 75.0 479.6 2.4 0.0 15.8 0.1 4.1 12.1 32.5 6.7 79.9 6.5 49.8 82.4 3.2 141.9 7.2 4.0 28.0 9.9 0.0 126.0 4.6 14.0 0.0 72.9 0.7 6.3 223.5 138.2 268.6 4.1 6.0 7.9 28.6 2.5 15.3 47.5 0.4 2.6 COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2044.3;Fibroblasts: 1944.4;Leydig cells: 556.0;Smooth muscle cells: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 1689.5;BJ: 3428.1;fHDF/TERT166: 5206.1;HSkMC: 2490.3;U-138 MG: 2687.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" 312.1 39.9 1.8 272.8 5.3 4.5 184.9 1.3 15.9 1331.8 12.0 223.2 37.7 531.4 23.4 110.2 234.1 1211.3 126.6 1.5 1.9 34.7 29.7 139.0 78.1 3.2 1.4 377.3 39.8 14.1 80.5 503.5 2.0 137.5 46.5 0.4 51.3 98.6 21.2 362.0 86.6 801.2 2.2 46.9 109.9 38.2 17.3 14.4 50.8 13.0 21.1 616.3 342.2 6.7 6.0 5.0 16.4 3.2 702.9 1689.5 29.2 3428.1 915.8 826.6 517.6 64.2 14.6 0.6 7.8 5206.1 5.7 9.1 8.3 3.4 150.1 5.2 6.1 0.4 92.2 4.2 1309.3 1.2 0.8 2490.3 45.7 1016.2 4.6 126.9 0.5 4.8 2.2 0.4 425.4 8.5 1.4 1.0 17.0 10.7 10.5 6.1 2.1 2.7 3.9 0.2 2.0 8.8 5.6 5.0 0.2 245.4 39.8 0.6 1.5 2687.4 562.6 405.0 16.2 2.8 5.9 0.7 200.1 1.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 5.3 1.3 15.9 1.5 1.9 3.2 1.4 2.0 2.2 17.3 6.7 66.9 9.6 13.8 0.0 2.1 188.0 12.4 31.6 10.8 0.2 9.1 10.0 12.5 5.7 13.2 7.3 0.0 45.7 1.7 1.4 0.0 13.3 1.9 64.6 2044.3 33.4 3.0 0.0 0.1 4.2 45.5 1944.4 17.9 49.2 2.5 8.1 378.0 3.4 67.6 0.0 0.3 5.4 6.1 0.3 318.1 18.2 556.0 13.1 188.5 12.2 0.0 2.5 0.0 0.0 0.0 23.8 0.3 268.1 1.3 10.7 0.1 0.7 9.8 0.2 78.9 74.8 1024.9 4.0 2.6 4.3 163.5 111.8 29.4 57.3 2.9 9.1 COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1831.7;gallbladder: 1378.0;smooth muscle: 1416.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 774.5;Fibroblasts: 2148.2;Glandular and luminal cells: 592.2;Leydig cells: 991.9;Peritubular cells: 501.0;Smooth muscle cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3899.2;ASC TERT1: 4637.0;BJ: 3995.6;BJ hTERT+: 2901.2;fHDF/TERT166: 13615.1;HSkMC: 4058.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 133.7" "CAB032650, HPA059738" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 27000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB032650: AB_2082039, HPA059738: AB_2684116" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.15e-2)" "unprognostic (7.38e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-3)" 514.8 52.4 6.8 266.2 9.3 2.0 314.5 7.1 17.4 1831.7 18.1 175.7 61.1 411.2 61.6 263.2 206.6 1378.0 275.4 6.0 6.8 40.8 27.4 229.5 91.6 8.7 6.7 297.2 57.1 32.5 33.5 624.6 7.9 196.2 141.8 1.6 60.2 232.3 51.6 424.6 103.2 1416.9 8.8 69.3 89.1 136.6 15.6 32.8 86.4 102.1 60.1 805.6 295.2 8.2 0.1 0.0 22.8 1488.5 3899.2 4637.0 1.3 3995.6 2901.2 642.6 850.5 0.0 2.8 0.3 2.7 13615.1 0.0 0.6 2.2 1.5 160.9 0.1 0.2 0.1 0.0 0.0 1018.6 1.1 0.5 4058.4 0.1 507.9 2.4 0.3 0.5 0.0 0.3 0.3 551.0 0.0 0.6 1.5 2.5 0.0 6.3 0.5 0.8 0.8 0.1 0.0 12.9 1.4 0.3 1.0 0.1 296.0 2.1 0.1 15.9 1626.3 0.8 1022.7 115.5 1.2 0.1 0.4 408.6 0.5 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 9.3 7.1 17.4 6.0 6.8 8.7 6.7 7.9 8.8 15.6 8.2 112.9 3.2 12.9 1.0 0.8 223.1 0.7 9.3 4.6 0.2 7.2 8.6 21.7 0.0 3.3 1.8 0.0 31.5 2.5 0.0 0.0 3.0 8.4 183.2 774.5 57.2 0.0 0.0 0.0 0.2 31.7 2148.2 26.5 592.2 10.1 16.4 258.8 1.9 116.9 0.0 0.1 0.0 0.0 1.0 394.5 45.1 991.9 16.7 238.3 97.4 2.6 3.2 0.0 0.0 0.2 5.2 0.0 501.0 4.5 1.0 0.0 0.5 0.8 0.4 302.4 249.9 770.7 9.9 4.5 6.2 187.4 70.7 30.6 214.8 0.0 0.8 COL27A1 "FLJ11895, KIAA1870, MGC11337" ENSG00000196739 "Collagen type XXVII alpha 1 chain" Q8IZC6 9 114155537-114312511 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 93.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 60.1;Extravillous trophoblasts: 75.5;Gastric mucus-secreting cells: 43.8;Hepatocytes: 43.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 29.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 54.8;Hep G2: 48.7" "Low region specificity" "Detected in some" "Region enriched" "Detected in all" 19 "cerebellum: 71.0" "HPA021884, HPA048471" Uncertain "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" "HPA021884: AB_2670857, HPA048471: AB_2680407" "unprognostic (4.45e-2)" "unprognostic (3.27e-1)" "unprognostic (1.32e-1)" "unprognostic (5.00e-2)" "prognostic unfavorable (7.11e-4)" "unprognostic (4.13e-1)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (6.25e-2)" "unprognostic (1.71e-1)" "unprognostic (1.09e-3)" "unprognostic (3.31e-1)" "unprognostic (3.41e-2)" "unprognostic (2.97e-2)" "unprognostic (9.48e-2)" "unprognostic (6.21e-3)" "unprognostic (3.50e-3)" 9.2 8.7 4.0 3.5 3.4 0.3 9.1 29.6 4.8 93.7 3.0 11.2 3.9 39.7 16.1 8.1 16.7 7.9 10.9 3.6 4.7 33.1 42.7 7.0 3.1 7.0 7.9 27.6 21.2 1.0 4.1 11.7 6.5 22.5 1.4 1.5 5.4 13.7 5.8 15.7 6.9 10.5 4.9 4.7 11.9 6.4 6.4 9.2 13.5 2.8 2.2 8.1 37.7 4.3 3.8 7.8 17.9 6.6 1.3 1.9 54.8 8.7 5.9 6.3 5.2 8.1 0.2 0.0 2.1 4.3 4.7 9.2 6.2 8.1 3.4 0.0 0.7 0.0 7.5 48.7 1.9 0.0 19.8 4.9 2.3 7.6 3.4 3.6 9.4 7.4 0.0 1.9 3.6 1.8 0.1 3.5 6.5 15.1 2.1 25.9 18.1 3.7 14.6 4.2 0.3 0.2 0.4 0.2 1.1 6.8 1.6 5.8 8.9 5.5 11.1 0.7 13.9 1.0 0.0 0.0 4.5 0.1 8.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 3.4 29.6 4.8 3.6 4.7 7.0 7.9 6.5 4.9 6.4 4.3 2.9 3.2 23.0 15.0 0.8 27.1 4.9 14.2 18.2 1.2 24.3 22.1 34.4 60.1 6.1 9.2 6.2 1.0 2.0 0.5 3.9 12.8 3.7 3.3 25.3 7.1 4.8 0.0 11.0 5.1 75.5 15.0 43.8 11.5 0.0 6.9 3.6 43.6 6.5 1.7 4.6 1.8 0.0 1.0 4.1 1.6 19.3 0.8 23.2 8.4 0.1 5.6 0.0 25.6 0.8 4.7 2.5 4.5 0.4 10.6 0.3 9.8 0.6 1.4 26.3 4.9 40.1 0.5 2.0 5.8 22.4 2.3 1.4 23.8 2.4 3.2 COL2A1 "AOM, SEDC, STL1" ENSG00000139219 "Collagen type II alpha 1 chain" P02458 12 47972967-48004554 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, FDA approved drug targets, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 19.1;pituitary gland: 9.2;retina: 5.6;stomach 1: 12.5" "Cell type enhanced" "Detected in some" "Early spermatids: 15.4;Enteroendocrine cells: 43.9;Late spermatids: 9.7;Muller glia cells: 22.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 156.3;HAP1: 98.9;HEK 293: 36.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002214, HPA055753" Approved Approved Nucleoplasm "Secreted to extracellular matrix" No NA 1400000 "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Nucleoplasm "CAB002214: AB_563666, HPA055753: AB_2682908" "unprognostic (7.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.58e-1)" "unprognostic (3.44e-1)" "unprognostic (2.88e-2)" "unprognostic (3.08e-2)" "unprognostic (8.63e-2)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (3.12e-2)" "unprognostic (1.31e-4)" "unprognostic (2.64e-1)" "unprognostic (3.44e-3)" "unprognostic (1.89e-1)" "unprognostic (2.93e-1)" "unprognostic (2.07e-1)" "unprognostic (1.02e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.2 0.1 0.0 0.2 0.0 0.2 19.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.2 0.2 1.3 0.0 0.0 9.2 0.3 0.3 1.0 0.3 5.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.5 2.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 156.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.7 0.0 0.0 0.0 98.9 0.0 0.0 0.0 36.3 0.2 0.0 5.7 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.0 0.0 0.1 0.0 2.9 0.0 0.0 0.1 2.2 0.1 0.0 0.0 0.0 11.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.3 0.2 0.2 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.0 0.6 5.7 0.9 0.0 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 15.4 0.3 0.1 0.2 43.9 0.0 0.2 0.0 0.3 0.5 0.0 0.2 0.0 1.3 0.0 0.0 0.2 0.0 0.1 0.6 0.0 0.0 0.0 9.7 0.9 0.0 0.0 0.0 0.0 22.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.2 0.0 1.7 0.0 0.9 0.3 0.6 1.1 0.0 0.0 0.8 0.1 0.1 1.7 0.1 COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2369.0;gallbladder: 2092.8;placenta: 1981.7;smooth muscle: 2140.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2812.0;Fibroblasts: 1764.2;Smooth muscle cells: 643.0;Theca cells: 466.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 15.0;thalamus: 10.9;white matter: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 1362.4;ASC diff: 2465.0;ASC TERT1: 4252.6;fHDF/TERT166: 1815.7;HHSteC: 1690.0;HSkMC: 3189.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 61.1" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 32000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB016766: , CAB059993: AB_2314211, HPA007583: AB_1078548" "unprognostic (1.12e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (6.77e-3)" "unprognostic (3.57e-3)" "unprognostic (2.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.59e-10)" "unprognostic (1.70e-3)" "unprognostic (3.76e-2)" "unprognostic (7.61e-2)" "unprognostic (6.17e-3)" 763.6 48.9 1.1 575.5 2.3 1.1 340.0 1.4 15.0 2369.0 11.5 275.9 84.5 768.9 60.9 298.5 177.6 2092.8 234.6 1.3 1.4 42.9 97.4 187.0 119.0 1.8 2.0 146.9 45.2 37.0 13.6 1981.7 2.2 147.5 334.7 0.0 65.6 276.9 67.1 329.8 152.5 2140.7 1.9 134.7 156.9 63.5 10.9 40.9 71.8 71.8 73.1 1097.6 273.8 4.6 0.0 0.2 1362.4 53.0 2465.0 4252.6 0.9 558.6 495.3 239.4 212.8 8.1 0.0 0.6 0.3 1815.7 0.1 0.8 1.1 1.0 26.4 0.0 0.9 0.7 228.9 0.2 1690.0 2.0 0.6 3189.5 0.0 291.5 46.9 1.0 12.5 0.0 0.4 0.0 146.4 0.0 0.2 1.4 2.6 0.1 1.7 0.3 38.5 0.5 0.0 7.2 1.3 21.1 14.5 0.4 0.0 954.8 0.1 0.0 0.7 2.3 28.0 117.3 0.5 2.8 1.3 0.4 0.5 1.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.3 1.4 15.0 1.3 1.4 1.8 2.0 2.2 1.9 10.9 4.6 111.8 3.2 13.7 0.0 0.6 171.6 0.4 1.9 3.4 0.0 7.7 9.9 11.1 0.0 1.3 0.0 0.0 57.9 1.6 0.0 0.0 2.4 29.0 75.4 2812.0 68.4 6.0 0.0 0.0 0.0 58.1 1764.2 4.1 60.7 6.3 9.7 235.2 0.9 91.1 0.0 0.2 0.0 0.0 0.6 275.3 20.8 323.1 17.5 172.5 20.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 235.9 1.5 0.6 0.0 0.2 1.6 0.0 453.6 224.3 643.0 0.9 1.5 2.2 155.7 126.3 29.1 466.8 0.0 0.4 COL4A1 ENSG00000187498 "Collagen type IV alpha 1 chain" P02462 13 110148963-110307157 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 900.3" "Cell type enhanced" "Detected in many" "Adipocytes: 401.4;Endometrial stromal cells: 312.2;Endothelial cells: 385.9;Extravillous trophoblasts: 672.4;Sertoli cells: 506.2;Smooth muscle cells: 415.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.4" "Cell line enhanced" "Detected in many" "ASC diff: 501.6;EFO-21: 915.3;TIME: 331.3" "Low region specificity" "Detected in all" CAB001695 Approved "Secreted to extracellular matrix" NA NA 75000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB001695: " "unprognostic (3.82e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (2.27e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (2.40e-1)" "unprognostic (1.10e-1)" "unprognostic (6.51e-3)" "unprognostic (1.06e-2)" "unprognostic (9.79e-2)" "unprognostic (1.73e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.47e-3)" "unprognostic (1.72e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-2)" 348.4 33.6 10.8 135.9 5.2 0.4 130.4 3.7 9.0 65.7 8.9 108.5 24.8 105.3 14.8 40.8 64.1 116.8 81.9 12.6 5.2 53.4 22.1 137.0 27.7 9.1 7.0 27.0 36.0 36.3 12.8 900.3 7.5 53.6 30.4 1.8 19.0 85.6 40.1 25.2 43.4 312.7 6.8 76.3 50.1 10.7 13.7 10.7 54.7 47.0 11.1 120.8 38.2 6.9 40.0 15.2 195.9 0.3 501.6 148.9 274.9 246.2 59.5 134.0 65.3 4.2 0.8 0.1 915.3 46.2 59.7 26.8 0.0 55.8 30.3 1.3 29.5 0.2 28.2 0.0 142.8 0.0 0.4 49.7 8.9 132.8 59.4 212.8 207.7 0.1 0.3 0.2 31.1 0.1 0.1 0.8 28.1 0.2 3.6 0.4 58.6 0.1 278.8 0.0 1.4 29.8 0.1 0.4 61.0 192.4 0.1 13.9 331.3 39.9 121.4 1.0 97.4 0.3 1.8 3.9 0.4 0.7 297.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 10.8 5.2 3.7 9.0 12.6 5.2 9.1 7.0 7.5 6.8 13.7 6.9 401.4 41.7 8.9 5.2 1.9 14.0 9.7 8.5 2.8 1.0 3.5 16.5 41.1 10.0 0.9 23.9 0.0 49.7 0.5 0.1 1.9 22.6 0.7 19.8 312.2 385.9 0.0 0.0 10.5 0.2 672.4 211.8 1.5 48.7 1.3 215.8 134.6 1.3 27.7 0.0 18.9 0.5 0.0 4.4 19.2 2.8 38.5 4.2 30.2 36.5 0.6 2.5 0.0 1.0 0.9 0.6 0.1 109.4 0.5 6.2 0.5 26.7 2.8 0.4 506.2 142.8 415.1 1.2 5.0 0.8 15.2 45.0 4.2 45.9 0.6 2.2 COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 474.0" "Cell type enhanced" "Detected in many" "Adipocytes: 313.6;Endometrial stromal cells: 308.3;Endothelial cells: 278.2;Extravillous trophoblasts: 512.9;Granulosa cells: 223.8;Sertoli cells: 374.7;Smooth muscle cells: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1041.3;WM-115: 428.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA 2700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" 240.5 51.2 15.1 103.5 2.3 0.6 153.5 1.7 5.9 111.6 3.4 282.0 29.5 219.4 10.4 51.8 122.9 84.2 113.0 19.3 1.8 71.7 19.1 181.7 22.8 4.3 7.8 51.9 32.6 25.6 17.5 474.0 6.0 121.3 18.9 2.8 35.0 95.8 44.7 45.2 84.1 226.8 2.6 121.5 96.4 15.7 11.5 7.9 74.9 21.5 7.1 186.2 74.4 2.9 88.9 45.7 218.7 0.6 213.7 99.0 312.8 307.9 97.4 167.3 76.1 2.5 0.7 0.6 1041.3 60.0 75.0 85.4 0.1 82.4 27.3 28.1 46.3 0.2 76.6 0.7 150.5 0.5 1.0 42.8 4.5 114.8 71.2 193.5 158.5 0.0 1.3 0.9 25.4 0.3 0.3 12.1 34.2 0.8 11.7 0.6 87.8 0.4 125.6 0.0 6.4 35.4 0.3 0.9 81.2 84.7 0.6 6.7 327.7 94.9 237.9 2.3 161.9 0.6 3.0 7.4 5.8 0.4 428.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 2.3 1.7 5.9 19.3 1.8 4.3 7.8 6.0 2.6 11.5 2.9 313.6 83.3 5.8 17.9 2.9 9.6 8.0 16.3 1.8 2.4 7.0 56.8 31.8 20.0 1.8 53.3 0.0 77.4 0.1 10.0 1.9 39.0 1.7 19.4 308.3 278.2 0.0 8.0 17.7 4.4 512.9 159.1 5.6 50.1 1.3 223.8 102.1 1.8 30.9 0.0 44.0 7.0 2.0 3.3 13.3 3.4 60.6 3.8 39.2 46.9 2.0 7.3 0.0 5.5 1.1 2.8 1.4 176.0 1.5 12.3 23.9 32.7 2.1 0.3 374.7 64.7 338.9 0.9 8.5 0.7 7.0 67.2 3.6 49.4 5.4 2.4 COL4A3 ENSG00000169031 "Collagen type IV alpha 3 chain" Q01955 2 227164624-227314792 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 52.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 169.9;Bipolar cells: 62.1;Cone photoreceptor cells: 398.2;Muller glia cells: 143.1;Oligodendrocyte precursor cells: 84.9" "Group enriched" "Detected in some" 6 "lung cancer: 1.7;renal cancer: 3.0;thyroid cancer: 5.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Lineage enriched" "Detected in single" 7 "B-cells: 1.0" "Cell line enhanced" "Detected in some" "HeLa: 18.8;hTERT-RPE1: 14.5;Karpas-707: 9.9;RPTEC TERT1: 11.0;U-266/70: 9.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042064 Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum" "HPA042064: AB_10794410" "unprognostic (4.81e-2)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (9.28e-6)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (1.84e-2)" "unprognostic (7.07e-3)" "unprognostic (2.30e-1)" "unprognostic (9.09e-3)" "unprognostic (9.30e-2)" "unprognostic (3.02e-2)" "prognostic favorable (2.51e-7)" "unprognostic (1.78e-1)" "unprognostic (3.10e-2)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" 0.6 11.5 1.9 2.1 1.8 0.3 1.0 1.5 1.7 0.4 21.5 0.8 0.7 1.2 16.3 1.0 2.1 3.2 8.9 1.4 2.0 30.5 0.6 15.0 2.9 3.3 3.1 3.9 5.0 0.2 16.2 0.2 2.7 6.0 1.0 52.9 1.2 9.9 22.2 0.5 6.7 0.8 1.6 7.2 1.8 1.7 6.3 0.4 20.5 15.2 5.6 1.4 1.2 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.8 0.0 0.0 0.3 1.1 0.1 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 1.2 0.0 9.9 0.0 0.4 0.0 0.1 1.4 0.0 0.0 0.1 0.0 3.2 11.0 2.3 0.5 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 9.0 3.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 1.5 1.7 1.4 2.0 3.3 3.1 2.7 1.6 6.3 2.2 0.5 169.9 31.7 3.9 14.0 0.1 0.1 0.1 0.6 62.1 0.1 0.9 2.6 1.5 9.3 42.3 398.2 0.1 0.1 0.0 0.0 0.1 0.7 0.1 0.2 2.4 0.0 0.0 5.5 1.0 0.0 4.6 0.5 0.3 1.3 22.8 0.4 0.2 0.0 1.7 14.1 0.0 0.0 0.0 0.3 0.3 8.4 0.3 1.8 13.1 0.0 143.1 0.0 84.9 3.6 1.0 0.0 12.0 8.0 0.1 0.0 1.9 0.1 11.9 13.1 11.7 3.6 0.4 0.0 0.3 0.3 0.0 1.2 0.1 0.0 0.0 COL4A4 CA44 ENSG00000081052 "Collagen type IV alpha 4 chain" P53420 2 227002714-227164453 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Collecting duct cells: 46.0;Cone photoreceptor cells: 56.3;Granulosa cells: 62.6;Muller glia cells: 78.6;Oligodendrocyte precursor cells: 55.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 4.1" "Lineage enriched" "Detected in single" 5 "B-cells: 4.1" "Cell line enhanced" "Detected in some" "HeLa: 34.3;hTERT-RPE1: 27.2;Karpas-707: 8.9;RPTEC TERT1: 14.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.31e-2)" "unprognostic (7.56e-2)" "unprognostic (6.65e-2)" "unprognostic (4.88e-5)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" "unprognostic (8.50e-3)" "unprognostic (5.14e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "prognostic favorable (2.30e-13)" "unprognostic (1.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" "unprognostic (4.15e-2)" 1.0 6.9 1.3 2.1 1.1 0.1 0.7 0.9 0.9 0.5 14.2 0.9 0.9 2.0 7.2 1.1 2.1 4.4 9.2 1.0 1.3 14.0 1.6 8.3 2.8 3.1 2.2 2.0 5.5 0.6 10.2 0.3 2.6 4.5 0.8 8.4 0.7 8.3 6.9 0.3 2.4 1.6 1.5 1.9 1.2 1.3 4.4 0.9 9.9 5.7 4.5 2.9 0.9 1.3 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.3 0.2 0.1 0.6 0.0 0.7 0.0 1.7 0.0 0.7 0.1 3.1 1.1 0.2 0.0 3.4 0.0 34.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 27.2 0.0 1.1 0.0 8.9 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 14.5 5.6 0.8 0.0 2.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 2.7 0.0 0.3 6.7 5.3 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.3 0.0 0.0 4.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.3 1.1 0.9 0.9 1.0 1.3 3.1 2.2 2.6 1.5 4.4 1.3 2.0 73.7 24.1 3.6 11.1 0.5 0.4 0.2 0.0 29.1 0.5 1.3 3.5 8.6 6.2 46.0 56.3 0.0 1.4 0.1 1.9 0.3 0.8 0.3 1.8 5.2 1.2 0.0 2.5 3.8 0.0 8.1 1.5 0.9 0.0 62.6 2.5 0.7 0.1 0.0 10.4 0.1 2.0 0.3 1.5 4.3 25.1 0.8 0.0 12.2 0.0 78.6 0.0 55.3 3.4 4.1 0.1 27.1 14.9 0.2 0.0 3.6 0.0 8.5 0.0 16.8 8.6 0.1 0.6 0.2 0.0 0.0 1.4 0.9 0.3 0.1 COL4A5 "ASLN, ATS" ENSG00000188153 "Collagen type IV alpha 5 chain" P29400 X 108439838-108697545 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.9" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 713.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 87.7;HHSteC: 95.0;HUVEC TERT2: 92.8;TIME: 88.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077177 Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "HPA077177: " "unprognostic (2.58e-2)" "unprognostic (2.57e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.97e-2)" "unprognostic (7.27e-2)" "unprognostic (2.70e-1)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.41e-5)" "unprognostic (2.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (1.06e-1)" 7.4 5.6 25.2 2.3 57.4 0.0 8.1 38.2 40.8 38.1 20.0 5.8 3.8 59.2 25.4 9.6 37.5 18.2 10.9 27.0 33.7 16.9 2.4 8.5 1.2 47.7 43.1 23.0 3.8 16.8 19.7 14.5 47.4 37.0 5.6 6.1 7.4 32.9 7.6 26.4 6.3 47.2 36.4 5.5 34.5 6.0 45.3 2.7 10.5 4.4 1.0 47.6 22.7 102.9 4.5 26.7 47.2 14.9 18.0 10.6 0.3 2.8 11.7 14.2 23.2 24.0 1.9 4.2 0.0 2.0 8.6 21.7 13.2 45.2 17.8 6.7 11.7 3.4 87.7 2.9 95.0 0.0 13.5 49.2 53.6 17.4 37.2 45.2 92.8 0.0 0.2 0.1 13.9 2.0 0.1 0.5 14.0 0.0 16.0 0.1 0.0 0.2 35.9 26.7 0.0 0.0 70.2 2.2 6.0 65.6 12.9 0.0 88.8 9.5 2.8 6.4 4.0 1.9 0.0 0.0 8.2 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 57.4 38.2 40.8 27.0 33.7 47.7 43.1 47.4 36.4 45.3 102.9 1.0 6.4 7.3 72.5 0.0 26.9 29.7 29.4 17.1 0.5 14.8 14.7 10.0 2.8 14.2 20.2 0.0 0.7 0.0 0.0 0.0 0.4 0.1 7.4 45.4 4.6 0.0 0.0 1.1 0.9 0.4 12.3 3.1 5.7 1.3 2.0 4.2 0.5 0.4 0.0 1.5 0.2 6.1 0.3 2.1 1.7 20.2 0.6 1.8 20.6 0.0 11.1 0.0 3.5 713.9 0.4 0.0 36.9 0.0 18.1 0.0 0.1 8.2 0.6 6.6 2.4 18.3 0.4 0.9 4.2 15.9 0.7 1.1 21.5 0.1 24.7 COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.1;Fibroblasts: 134.9;Leydig cells: 61.2;Sertoli cells: 52.6;Skeletal myocytes: 78.3;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 446.6;fHDF/TERT166: 414.6;HeLa: 297.0;HHSteC: 265.8;SiHa: 290.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" 39.3 12.0 1.3 39.1 1.5 1.0 20.0 1.9 2.7 146.6 3.4 72.0 13.5 118.2 11.1 23.2 59.6 77.6 32.8 1.2 1.9 11.5 7.6 35.7 5.5 4.0 2.5 51.9 7.0 6.8 6.6 95.8 1.3 43.8 16.3 3.1 9.3 28.9 10.2 24.6 22.0 89.6 1.8 17.6 31.4 6.2 4.6 2.3 10.1 7.3 2.9 51.6 63.4 1.4 0.6 16.7 13.0 20.7 192.2 202.4 7.9 446.6 89.0 73.6 78.6 0.2 0.3 0.0 95.3 414.6 39.8 5.6 0.0 0.1 21.3 0.1 1.0 0.3 297.0 0.1 265.8 0.2 2.7 200.0 0.2 71.1 5.6 0.0 89.2 0.1 0.1 1.2 39.5 4.1 0.3 0.9 7.6 0.0 8.5 15.7 50.3 1.8 0.1 0.1 5.3 2.5 290.0 1.8 0.2 173.7 0.6 0.2 152.6 154.4 61.9 190.4 93.7 0.3 0.2 0.4 121.6 0.1 26.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 2.7 1.2 1.9 4.0 2.5 1.3 1.8 4.6 1.4 7.9 0.0 1.8 0.7 0.3 14.5 3.5 0.8 3.4 8.5 0.8 2.7 9.0 0.0 0.0 1.8 2.1 6.4 0.3 0.0 1.9 2.2 5.5 4.2 141.1 8.8 0.0 0.0 6.6 0.0 12.3 134.9 1.5 4.8 0.0 1.2 21.8 0.0 8.9 0.0 1.2 0.0 0.0 0.3 15.3 15.6 61.2 1.5 7.2 12.2 0.0 6.4 0.0 5.5 0.3 1.3 0.0 38.7 0.3 1.0 0.0 0.3 0.0 1.2 52.6 78.3 57.5 0.5 0.8 0.6 7.7 10.4 2.6 11.7 0.0 0.4 COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 186.0;Excitatory neurons: 185.2;Fibroblasts: 145.7;Skeletal myocytes: 76.4;Smooth muscle cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 447.8;BJ hTERT+ SV40 Large T+ RasG12V: 382.4;fHDF/TERT166: 430.3;HSkMC: 340.2;SuSa: 373.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" 61.0 4.8 2.3 42.5 5.7 0.2 25.7 0.0 15.6 83.4 3.1 48.7 10.0 43.4 32.7 23.6 21.2 81.9 19.5 17.6 0.8 6.3 12.4 26.1 9.3 2.0 17.4 25.2 7.1 7.5 7.3 111.5 3.8 14.8 25.4 1.6 7.4 12.8 7.8 12.9 22.8 98.3 1.9 10.0 21.5 6.8 1.0 4.7 9.8 26.8 10.3 57.3 29.7 2.5 0.4 93.5 143.9 67.5 212.0 285.3 0.8 213.7 242.3 447.8 382.4 63.2 0.7 0.2 2.2 430.3 23.2 1.6 4.1 2.3 153.3 0.9 1.3 1.0 2.1 0.6 282.6 0.6 0.4 340.2 7.8 129.8 45.3 92.2 108.5 0.9 0.5 0.4 109.1 2.4 0.3 0.3 20.9 0.9 124.3 0.5 33.9 0.4 0.5 24.9 2.0 1.4 5.2 2.5 5.2 373.0 2.1 0.2 91.6 212.8 22.9 52.6 44.6 0.8 0.4 0.6 32.2 0.1 235.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 5.7 0.0 15.6 17.6 0.8 2.0 17.4 3.8 1.9 1.0 2.5 36.7 0.0 1.5 29.7 0.3 26.1 0.2 7.2 6.2 1.3 1.6 3.7 2.8 0.0 0.7 1.8 0.0 4.6 0.2 0.5 1.9 0.6 0.7 22.4 186.0 9.1 38.7 0.0 185.2 0.7 3.9 145.7 0.5 5.1 0.0 4.2 25.7 7.4 6.6 0.0 23.8 0.2 4.1 0.3 27.4 1.7 48.7 1.4 21.4 25.3 0.6 0.7 0.0 21.6 10.9 1.1 0.1 19.5 0.4 0.3 0.1 1.0 1.9 0.8 46.0 76.4 116.0 3.9 1.8 2.0 18.8 6.2 2.8 27.4 0.0 0.4 COL7A1 "EBD1, EBDCT, EBR1" ENSG00000114270 "Collagen type VII alpha 1 chain" Q02388 3 48564073-48595329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 98.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 72.5;Basal respiratory cells: 59.3;Basal squamous epithelial cells: 67.2;Endometrial stromal cells: 45.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 41.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 65.7;HaCaT: 63.5;HBEC3-KT: 100.6;HDLM-2: 97.8;HeLa: 146.2;SiHa: 82.8" "CAB016357, HPA018877, HPA042420" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 6000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" Vesicles "CAB016357: AB_2229746, HPA018877: , HPA042420: AB_2677990" "unprognostic (2.69e-2)" "unprognostic (4.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.47e-1)" "unprognostic (4.93e-2)" "prognostic favorable (6.31e-4)" "unprognostic (7.56e-2)" "unprognostic (1.25e-2)" "unprognostic (5.59e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.74e-2)" "unprognostic (0.00e+0)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.86e-2)" 0.8 1.1 1.4 3.8 1.0 0.1 4.9 2.8 2.1 24.3 0.4 2.9 1.7 12.1 6.7 21.8 6.4 4.0 3.2 0.3 6.5 7.4 1.3 1.7 1.2 7.0 3.2 3.4 0.4 0.0 2.5 1.6 3.0 34.2 0.9 1.4 11.5 12.2 3.5 98.2 4.1 2.5 2.6 6.5 2.1 3.6 6.5 1.2 0.5 0.6 1.3 6.6 29.2 0.6 0.2 25.4 1.2 0.5 9.2 12.3 31.0 65.7 40.8 16.9 10.0 0.4 0.5 0.1 2.0 15.0 15.4 63.5 0.0 100.6 3.1 97.8 0.5 0.2 146.2 4.3 25.6 0.0 0.4 19.9 58.8 34.4 26.8 23.1 0.0 0.7 0.5 0.7 2.0 0.3 0.0 0.9 3.1 1.3 1.3 0.5 2.2 0.2 9.2 0.2 0.2 0.2 82.8 0.1 0.8 3.7 1.3 0.3 0.0 5.6 3.2 3.2 50.1 1.8 1.8 0.1 49.0 0.4 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 2.8 2.1 0.3 6.5 7.0 3.2 3.0 2.6 6.5 0.6 0.4 0.0 0.0 10.7 0.2 72.5 24.1 59.3 67.2 17.7 1.0 10.2 6.6 0.0 10.6 11.0 10.4 1.4 0.1 0.6 0.0 0.9 11.8 3.1 45.3 1.4 1.8 0.0 6.8 0.7 1.0 8.3 1.1 4.0 0.0 0.8 0.4 0.7 1.6 8.4 11.6 0.7 0.0 0.3 4.2 6.3 5.0 0.8 8.8 8.4 0.1 2.6 0.0 4.0 4.4 15.6 0.1 5.7 0.0 5.7 0.2 0.3 2.5 12.9 0.0 2.0 13.4 2.6 1.5 11.3 24.2 1.2 0.8 5.0 0.2 5.8 COL9A1 ENSG00000112280 "Collagen type IX alpha 1 chain" P20849 6 70216040-70303084 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "choroid plexus: 68.8" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 310.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 25.7;NTERA-2: 8.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA074749 Enhanced "Secreted to extracellular matrix" NA NA 120000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA074749: AB_2732266" "unprognostic (2.18e-2)" "unprognostic (2.16e-1)" "unprognostic (2.25e-2)" "unprognostic (3.48e-3)" "unprognostic (5.72e-2)" "unprognostic (5.32e-4)" "unprognostic (3.24e-3)" "unprognostic (8.79e-2)" "unprognostic (1.25e-1)" "unprognostic (8.68e-2)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (5.69e-2)" "unprognostic (1.54e-1)" "unprognostic (2.09e-1)" "unprognostic (2.78e-1)" "unprognostic (3.62e-2)" 0.2 0.0 5.1 0.1 5.3 0.0 0.1 4.5 5.6 0.8 68.8 1.3 0.8 0.3 0.1 0.1 0.2 0.3 9.1 5.6 5.7 1.2 0.0 0.0 0.0 7.1 5.8 0.0 0.3 0.1 5.1 0.0 6.0 15.2 0.5 9.5 1.5 0.3 0.0 0.1 0.9 0.2 5.1 0.0 1.5 4.1 5.3 0.1 0.4 0.3 0.0 1.3 2.9 6.3 0.0 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 5.3 4.5 5.6 5.6 5.7 7.1 5.8 6.0 5.1 5.3 6.3 0.6 0.0 0.0 2.3 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.1 3.7 0.0 0.0 0.0 4.2 0.0 0.0 1.0 1.9 0.0 21.4 1.2 0.1 0.8 1.2 0.0 1.4 0.2 0.0 0.5 0.0 1.7 0.0 1.0 0.0 0.0 0.1 35.3 6.7 0.5 0.0 0.0 0.0 11.6 0.0 0.1 0.0 2.8 0.1 68.5 0.0 310.1 0.6 0.0 0.8 0.4 0.0 2.3 0.0 0.1 0.0 3.2 0.0 0.3 4.2 0.6 2.3 0.1 0.0 0.0 0.0 0.1 0.8 0.1 COL9A2 "EDM2, MED" ENSG00000049089 "Collagen type IX alpha 2 chain" Q14055 1 40300489-40317813 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 86.2;pituitary gland: 108.1" "Cell type enhanced" "Detected in many" "Muller glia cells: 295.4;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 128.1" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 3.2;myeloid DC: 1.2" "Group enriched" "Detected in many" 6 "dendritic cells: 1.2;granulocytes: 3.2" "Group enriched" "Detected in many" 4 "HDLM-2: 98.6;Hep G2: 27.6;HMC-1: 90.3;THP-1: 105.0" "Low region specificity" "Detected in all" "HPA056316, HPA075286" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 510000 "Cluster 52: Eosinophils - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles Nucleoplasm "HPA056316: AB_2683099, HPA075286: AB_2732288" "unprognostic (1.42e-2)" "unprognostic (3.54e-2)" "unprognostic (8.94e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (4.46e-2)" "unprognostic (1.83e-3)" "unprognostic (2.06e-2)" "unprognostic (9.00e-3)" "unprognostic (1.73e-1)" "unprognostic (1.26e-1)" "unprognostic (1.56e-3)" "unprognostic (2.26e-1)" "unprognostic (1.16e-3)" "unprognostic (4.28e-2)" "unprognostic (2.56e-1)" "unprognostic (5.89e-2)" "unprognostic (1.71e-2)" 2.2 3.4 42.6 3.7 71.5 10.9 5.9 58.9 51.1 12.1 21.6 6.5 5.8 5.0 1.7 1.6 11.4 8.5 2.2 38.2 49.7 24.6 0.9 4.3 5.9 65.9 74.1 1.3 2.3 21.0 108.1 1.1 66.2 13.7 3.1 23.1 16.3 24.2 0.2 4.6 10.4 1.4 52.0 9.8 16.5 2.6 58.6 1.8 12.2 0.3 3.1 12.1 2.0 86.2 12.0 0.3 1.8 0.8 2.6 1.3 7.8 0.0 0.0 0.6 1.3 0.4 6.8 3.4 10.0 0.3 0.0 2.0 0.1 0.0 0.3 98.6 1.4 2.0 0.8 27.6 1.5 0.9 90.3 4.8 0.0 0.1 0.0 0.7 0.0 1.5 0.1 19.8 0.0 2.7 1.2 2.1 2.2 0.0 1.2 2.3 0.0 6.9 0.0 14.3 1.4 2.3 0.1 11.8 1.3 6.6 15.0 105.0 0.1 0.0 11.6 0.2 0.4 1.4 0.2 3.4 1.0 12.3 0.6 0.0 0.1 3.2 0.0 0.2 0.0 0.2 0.1 0.0 1.2 0.2 0.0 0.0 0.5 0.2 0.3 0.1 0.1 0.0 42.6 71.5 58.9 51.1 38.2 49.7 65.9 74.1 66.2 52.0 58.6 86.2 0.5 0.0 3.3 26.1 10.8 1.0 3.0 8.5 0.0 2.0 7.1 9.7 1.0 7.2 10.0 25.8 0.0 3.2 2.5 7.2 0.0 11.7 0.2 13.6 0.9 0.6 12.7 0.4 0.3 0.8 0.6 2.1 26.0 20.0 26.1 1.6 1.1 0.0 3.4 0.0 0.3 6.6 2.0 0.3 22.4 0.9 2.1 6.4 1.8 3.7 22.1 295.4 1.0 62.4 128.1 4.9 9.6 0.0 4.0 6.1 5.0 0.3 12.9 10.9 0.0 1.3 1.8 3.4 6.2 0.2 0.6 1.4 2.7 1.8 13.4 13.4 COL9A3 "DJ885L7.4.1, EDM3, FLJ90759, IDD, MED" ENSG00000092758 "Collagen type IX alpha 3 chain" Q14050 20 62816244-62841159 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.7;choroid plexus: 34.4;thyroid gland: 25.4" "Cell type enhanced" "Detected in many" "Early spermatids: 116.6;Late spermatids: 401.9;Muller glia cells: 95.8;Oligodendrocyte precursor cells: 84.9;Oligodendrocytes: 68.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 30.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 143.4;Hep G2: 59.6;SK-MEL-30: 51.1;WM-115: 57.8" "Low region specificity" "Detected in all" "HPA040125, HPA058323" Supported Approved "Nucleoplasm,Intermediate filaments" "Secreted to extracellular matrix" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Intermediate filaments" "HPA040125: AB_10805604, HPA058323: AB_2683679" "unprognostic (1.14e-3)" "unprognostic (2.14e-2)" "unprognostic (3.93e-1)" "unprognostic (1.21e-3)" "unprognostic (4.25e-2)" "unprognostic (2.39e-2)" "unprognostic (2.33e-1)" "unprognostic (1.24e-2)" "unprognostic (1.27e-1)" "unprognostic (1.25e-1)" "unprognostic (2.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (2.67e-1)" 1.6 1.5 17.5 0.7 35.7 0.0 2.8 22.4 21.6 3.3 34.4 12.1 0.7 1.2 0.2 1.3 1.7 0.1 6.3 13.0 16.5 2.9 0.6 0.4 0.2 37.4 31.0 1.7 7.6 0.1 14.0 0.5 24.2 3.2 0.1 1.6 23.6 1.2 0.5 1.9 3.1 0.1 20.5 0.3 2.7 20.7 31.6 0.1 25.4 0.0 0.0 2.8 3.8 39.7 0.2 0.3 0.3 0.2 0.0 0.8 143.4 0.1 0.0 0.1 0.0 1.6 0.2 0.0 13.1 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.9 0.0 8.2 59.6 0.3 0.0 0.5 2.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.3 0.0 0.0 1.0 0.7 6.4 8.2 0.0 2.5 0.0 1.8 0.0 0.1 0.0 1.5 0.2 0.1 51.1 4.6 0.2 5.4 0.0 0.0 0.7 0.1 1.0 0.2 0.1 0.0 0.2 0.0 57.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 35.7 22.4 21.6 13.0 16.5 37.4 31.0 24.2 20.5 31.6 39.7 1.6 3.2 0.0 1.0 26.1 3.2 2.2 1.2 1.8 0.9 2.1 2.5 1.6 0.0 0.2 5.5 10.4 5.1 0.4 0.7 1.9 3.6 116.6 2.7 0.4 3.7 4.2 1.3 2.5 0.0 46.4 15.3 6.1 0.7 0.0 0.6 2.5 6.8 2.2 0.0 2.0 3.3 0.0 2.2 0.9 401.9 4.1 1.7 3.6 0.0 0.5 95.8 0.0 84.9 68.9 0.1 7.3 1.5 44.0 1.2 2.3 23.7 2.5 3.7 0.0 0.8 1.0 2.9 7.8 0.9 7.0 4.0 1.4 3.7 2.0 1.0 COLEC10 CL-L1 ENSG00000184374 "Collectin subfamily member 10" Q9Y6Z7 8 118995452-119108455 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 65.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.9;Hepatic stellate cells: 10.4;Inhibitory neurons: 5.4;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 4.8" "Cancer enhanced" "Detected in some" "liver cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 3.4;SK-BR-3: 9.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 30000000 "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" "unprognostic (3.79e-4)" "unprognostic (6.25e-3)" "unprognostic (1.80e-3)" "unprognostic (7.73e-2)" "prognostic favorable (5.79e-4)" "unprognostic (1.05e-1)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.25e-2)" "unprognostic (9.02e-5)" "unprognostic (2.47e-1)" "unprognostic (1.82e-1)" "unprognostic (5.85e-5)" "unprognostic (7.12e-2)" 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.7 0.6 0.1 0.4 0.4 65.7 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 10.9 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 6.9 0.0 0.2 1.0 0.0 0.0 0.0 0.0 10.4 0.4 0.3 0.0 5.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.8 0.1 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 COLEC11 "CL-K1, MGC3279" ENSG00000118004 "Collectin subfamily member 11" Q9BWP8 2 3594832-3644644 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.2;liver: 143.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 37.4;Hepatic stellate cells: 89.3;Peritubular cells: 52.3;Proximal tubular cells: 127.1;Sertoli cells: 72.3" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HHSteC: 135.7;SH-SY5Y: 111.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA035241 Uncertain "Secreted to blood" NA NA 130000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035241: AB_10600701" "unprognostic (3.35e-1)" "unprognostic (4.73e-2)" "unprognostic (2.44e-3)" "unprognostic (2.31e-3)" "unprognostic (1.53e-2)" "unprognostic (1.40e-2)" "unprognostic (7.95e-3)" "unprognostic (5.85e-3)" "unprognostic (6.96e-2)" "unprognostic (2.04e-1)" "unprognostic (1.41e-1)" "unprognostic (6.96e-2)" "unprognostic (2.26e-1)" "unprognostic (9.27e-3)" "unprognostic (7.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.60e-1)" 13.8 40.6 1.0 0.9 1.0 1.9 3.3 4.8 1.9 1.8 6.9 2.8 3.5 1.2 0.4 1.6 4.4 54.2 46.6 1.4 0.9 24.8 143.1 2.4 1.9 1.3 0.5 46.4 13.8 1.2 5.8 2.4 1.3 3.3 0.6 0.5 0.6 1.1 0.6 1.4 3.8 1.1 0.4 3.8 3.1 7.4 1.1 4.0 17.0 0.8 0.2 7.1 1.0 1.3 0.2 1.4 0.7 2.5 0.0 0.0 11.7 0.7 0.0 0.3 0.2 0.7 0.2 0.3 4.0 0.1 0.4 0.4 0.1 0.4 0.3 0.2 0.8 0.6 1.4 5.0 135.7 0.2 1.0 1.6 0.1 0.2 0.0 0.4 0.1 0.8 11.1 0.8 0.0 0.1 0.0 0.8 0.6 0.2 0.9 0.0 0.0 0.5 0.0 0.3 2.1 111.7 1.6 1.1 0.8 0.3 0.5 1.0 0.0 0.0 0.7 0.6 0.5 3.2 26.2 1.5 0.3 1.3 0.6 0.7 0.1 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.2 0.9 0.3 0.1 0.2 0.1 0.0 1.0 1.0 4.8 1.9 1.4 0.9 1.3 0.5 1.3 0.4 1.1 1.3 7.3 0.0 0.0 0.7 0.6 1.0 0.0 0.0 2.8 0.5 0.1 0.3 1.2 0.0 0.0 0.0 0.0 1.6 0.0 0.1 17.6 0.0 0.3 1.1 22.0 4.2 0.0 0.0 2.2 0.0 1.4 37.4 0.0 0.6 0.0 1.3 89.3 7.9 2.5 0.0 0.9 0.1 0.0 1.9 0.3 0.5 7.5 0.8 3.6 1.0 0.0 1.4 0.0 0.5 0.2 0.1 0.0 52.3 0.0 0.2 0.0 127.1 0.0 0.1 72.3 0.3 18.0 1.3 11.6 0.6 0.9 1.2 0.7 27.0 0.0 0.1 COMP "EDM1, EPD1, MED, PSACH, THBS5" ENSG00000105664 "Cartilage oligomeric matrix protein" P49747 19 18782773-18791305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cell adhesion" Heparin-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 77.6;heart muscle: 65.3;skin 1: 80.6" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 19.3;Early spermatids: 37.0;Fibroblasts: 32.0;Glandular and luminal cells: 32.0;Late spermatids: 75.3;Spermatocytes: 16.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 859.6" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA077555 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA077555: " "unprognostic (1.26e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (9.08e-5)" "prognostic unfavorable (2.04e-4)" "unprognostic (8.05e-2)" "unprognostic (8.45e-2)" "unprognostic (3.62e-2)" "unprognostic (5.12e-2)" "unprognostic (1.65e-1)" "unprognostic (1.55e-2)" "unprognostic (2.18e-2)" "unprognostic (3.85e-1)" "prognostic unfavorable (1.52e-6)" "unprognostic (5.96e-3)" "unprognostic (1.44e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (6.95e-4)" 77.6 0.2 0.0 1.1 0.2 0.0 11.0 1.3 0.2 7.5 0.0 2.3 0.0 4.6 7.6 9.5 1.2 16.1 65.3 0.0 0.0 5.2 0.3 8.0 3.6 0.3 0.1 0.4 2.8 2.2 0.4 8.2 0.1 10.2 0.0 0.0 14.1 6.7 18.0 80.6 0.9 12.1 0.3 0.3 2.5 14.9 0.0 0.1 10.3 0.6 0.3 6.5 22.7 0.1 0.0 0.0 0.0 0.0 178.4 0.4 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 859.6 0.0 0.2 1.2 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.3 0.0 0.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.2 0.0 0.0 0.3 0.1 0.1 0.3 0.0 0.1 0.1 3.2 0.5 0.0 0.0 11.5 0.6 19.3 0.0 1.4 0.3 0.3 0.8 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 37.0 2.8 3.7 1.0 0.0 0.0 0.1 0.2 0.2 32.0 0.0 32.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 1.3 0.0 0.0 10.7 75.3 0.9 0.7 10.6 0.0 0.1 1.6 0.0 0.0 0.1 0.2 0.0 0.7 0.0 0.3 0.0 0.0 0.7 0.4 6.6 2.4 4.2 16.8 1.6 0.0 7.1 0.5 1.0 0.0 0.2 0.3 COPB2 "beta'-COP, betaprime-COP" ENSG00000184432 "COPI coat complex subunit beta 2" P35606 3 139353946-139389736 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036867, HPA058180" Approved Approved "Endoplasmic reticulum,Golgi apparatus" NA NA 63000 "Cluster 18: Basophils - Vesicular transport" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "Golgi apparatus" "HPA036867: AB_10672271, HPA058180: AB_2683630" "unprognostic (3.37e-2)" "unprognostic (2.04e-1)" "unprognostic (9.38e-2)" "unprognostic (6.93e-2)" "unprognostic (1.31e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (2.41e-7)" "unprognostic (5.59e-2)" "unprognostic (2.14e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (8.11e-2)" "unprognostic (1.51e-2)" "unprognostic (6.44e-2)" "unprognostic (1.14e-1)" "unprognostic (6.05e-2)" "unprognostic (4.95e-2)" 46.7 58.2 17.9 50.5 19.7 22.3 60.4 20.4 21.0 76.5 35.9 62.5 57.4 48.5 62.5 55.0 47.5 48.4 47.9 17.4 21.8 52.9 71.1 44.3 44.8 20.5 18.9 38.9 89.7 68.2 60.0 68.9 20.4 72.2 71.7 37.0 71.1 57.0 33.5 37.4 53.4 63.5 20.8 42.8 60.7 35.0 20.2 54.4 64.3 31.2 61.5 56.2 42.2 25.0 192.1 84.0 111.2 99.0 247.2 214.9 96.8 223.9 235.9 158.2 204.7 143.4 83.5 90.2 203.0 287.1 145.1 110.9 136.2 141.0 210.6 139.0 85.2 138.2 114.9 152.3 152.7 121.9 139.7 160.1 114.7 132.2 138.5 178.6 161.6 76.5 86.7 105.7 199.4 138.6 59.4 59.7 102.2 215.0 99.5 75.8 93.6 149.5 141.2 133.4 85.2 61.7 254.6 212.0 147.2 168.6 193.2 123.2 185.1 90.3 66.4 122.8 83.7 148.0 80.8 129.7 115.2 61.0 138.0 74.4 49.8 52.0 36.0 56.3 35.8 35.3 31.0 37.6 57.7 23.8 24.2 31.1 45.0 44.1 57.2 30.2 38.1 44.2 17.9 19.7 20.4 21.0 17.4 21.8 20.5 18.9 20.4 20.8 20.2 25.0 36.6 57.7 46.6 18.3 45.8 19.6 39.5 61.2 29.6 38.0 41.3 29.3 58.5 32.9 74.5 20.2 31.3 83.3 34.9 52.4 41.1 83.4 40.8 64.9 62.9 45.2 63.9 51.1 25.1 82.1 76.1 66.6 75.4 54.8 45.0 50.4 36.4 48.5 52.7 42.1 25.5 86.7 46.8 34.6 21.3 8.6 54.7 42.8 21.4 13.1 60.1 62.0 29.9 20.1 30.8 79.7 34.8 50.0 118.6 46.6 46.9 42.4 108.6 51.1 19.7 47.3 69.6 83.1 45.6 36.5 14.9 133.1 37.5 74.4 44.7 52.9 COX7B ENSG00000131174 "Cytochrome c oxidase subunit 7B" P24311 X 77899440-77907376 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1122.9;tongue: 756.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2237.0;Distal tubular cells: 2283.3;Proximal tubular cells: 1865.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058041 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA058041: AB_2683587" "unprognostic (1.24e-2)" "unprognostic (1.76e-3)" "unprognostic (8.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.53e-1)" "unprognostic (1.13e-1)" "unprognostic (3.22e-1)" "unprognostic (1.65e-1)" "unprognostic (2.11e-2)" "unprognostic (1.06e-1)" "unprognostic (2.26e-1)" "unprognostic (8.10e-2)" "prognostic favorable (6.80e-6)" "unprognostic (8.58e-2)" "unprognostic (4.62e-1)" "unprognostic (6.38e-2)" "prognostic favorable (2.43e-4)" 99.1 94.8 198.6 74.5 200.9 205.6 81.5 218.2 376.7 46.2 228.4 176.5 182.4 50.2 94.4 72.1 55.3 42.0 326.8 202.2 214.7 222.6 181.5 45.7 64.3 203.2 202.9 38.7 49.1 301.3 21.3 53.6 205.4 61.6 158.5 184.1 93.5 65.9 1122.9 42.8 156.7 74.8 205.0 51.3 125.1 19.1 208.4 96.6 54.3 756.7 76.3 87.8 19.6 207.3 242.8 239.4 257.8 214.6 111.8 90.1 179.5 159.7 78.8 101.8 113.1 259.6 213.0 158.6 271.8 96.1 333.1 302.5 298.7 183.6 112.7 138.9 372.7 218.5 441.3 343.5 104.2 441.1 185.5 133.0 137.0 154.2 129.9 173.0 113.0 186.1 186.3 409.8 118.6 282.6 350.6 445.5 253.4 972.4 614.5 250.5 297.0 594.4 344.6 420.8 177.3 158.1 305.8 396.8 334.2 209.0 148.7 295.0 149.7 91.1 222.0 232.6 167.7 157.9 407.0 364.8 212.2 504.2 130.5 212.5 226.7 168.6 152.7 326.5 165.2 213.6 166.5 174.8 303.7 146.3 155.7 185.6 142.8 205.9 316.1 213.2 238.6 261.1 198.6 200.9 218.2 376.7 202.2 214.7 203.2 202.9 205.4 205.0 208.4 207.3 238.9 134.6 178.0 28.1 247.7 297.5 297.2 1151.7 225.9 111.4 204.5 244.9 2237.0 487.6 463.6 369.6 35.5 412.9 272.2 1219.8 2283.3 504.6 20.8 424.0 243.9 210.0 516.0 428.5 11.2 395.7 424.2 227.2 382.8 356.4 226.3 134.7 194.5 1179.5 718.3 47.1 14.8 922.1 734.5 438.9 432.1 43.1 199.4 368.3 538.9 10.3 488.1 214.0 258.5 12.5 19.5 425.5 1090.3 176.4 297.3 307.7 1516.9 1865.2 314.0 174.3 210.4 274.2 315.4 81.4 108.8 583.4 345.5 591.7 258.4 166.9 978.4 472.5 CPAMD8 "K-CAP, KIAA1283, VIP" ENSG00000160111 "C3 and PZP like alpha-2-macroglobulin domain containing 8" Q8IZJ3 19 16892951-17026815 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.7;prostate: 34.1;seminal vesicle: 36.1" "Cell type enhanced" "Detected in many" "Adipocytes: 19.5;Alveolar cells type 1: 22.4;Alveolar cells type 2: 29.8;Collecting duct cells: 27.6;Leydig cells: 31.4;Prostatic glandular cells: 19.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "BEWO: 19.5;EFO-21: 12.6;T-47d: 34.4" "Region enriched" "Detected in single" 8 "spinal cord: 5.6" "HPA031327, HPA031328, HPA031329, HPA031330" Uncertain Uncertain "Focal adhesion sites" "Secreted to blood" NA NA 2700000 "Cluster 21: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 43: Cardiomyocytes - Nuclear processes" "Focal adhesion sites" "HPA031327: AB_2673829, HPA031328: AB_2673830, HPA031329: , HPA031330: AB_10603788" "unprognostic (4.71e-3)" "unprognostic (1.07e-2)" "unprognostic (4.20e-2)" "unprognostic (2.76e-2)" "unprognostic (4.32e-2)" "unprognostic (4.06e-3)" "unprognostic (7.85e-2)" "unprognostic (9.30e-2)" "unprognostic (1.58e-1)" "unprognostic (2.71e-2)" "unprognostic (1.62e-1)" "unprognostic (4.24e-2)" "unprognostic (8.69e-2)" "unprognostic (1.01e-3)" "unprognostic (2.08e-1)" "unprognostic (8.45e-2)" "unprognostic (1.80e-2)" 6.8 2.5 7.9 0.5 15.6 0.5 6.2 35.7 3.7 7.7 4.3 1.0 0.3 2.2 10.5 0.5 1.8 0.3 23.8 2.4 7.2 19.0 0.8 15.0 0.2 23.5 26.2 1.6 0.4 3.2 4.1 4.2 21.3 34.1 0.1 0.5 2.8 36.1 2.8 1.6 1.2 0.4 25.5 1.7 0.8 2.3 17.8 1.2 21.0 2.9 0.3 1.6 3.1 32.0 0.0 0.0 0.8 0.0 0.0 0.0 19.5 0.0 0.1 0.0 0.0 0.0 0.0 0.5 12.6 0.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 1.1 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 3.2 0.7 0.0 0.0 1.9 0.0 0.1 0.5 2.8 0.1 0.0 0.0 0.6 0.0 0.1 34.4 0.2 0.0 0.1 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 15.6 35.7 3.7 2.4 7.2 23.5 26.2 21.3 25.5 17.8 32.0 19.5 22.4 29.8 3.6 0.5 0.9 10.1 5.8 1.2 2.3 7.5 9.0 6.1 1.5 10.7 27.6 0.0 9.1 0.4 1.0 0.0 0.9 1.8 3.1 3.2 15.1 0.0 0.0 0.8 0.0 6.1 2.8 2.0 6.1 2.5 1.8 11.7 0.3 3.1 0.0 0.8 0.7 0.0 6.3 1.4 4.3 31.4 5.8 0.0 1.9 3.3 0.1 2.1 1.5 1.0 1.2 1.4 6.4 3.4 19.3 0.0 0.1 4.7 0.1 0.0 1.6 2.1 6.2 1.2 0.4 0.6 6.0 0.4 1.7 0.2 6.0 CPLANE1 "C5orf42, FLJ13231, Hug, JBTS17" ENSG00000197603 "Ciliogenesis and planar polarity effector 1" Q9H799 5 37106228-37249376 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 19.4;Collecting duct cells: 22.0;Endometrial ciliated cells: 50.3;Endometrial stromal cells: 42.9;Glandular and luminal cells: 20.6;Granulosa cells: 40.8;Theca cells: 18.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 21.9;SiHa: 48.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036775, HPA036776" Approved Approved Cytosol NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA036775: AB_10669914, HPA036776: AB_2675308" "unprognostic (3.06e-1)" "unprognostic (2.00e-1)" "unprognostic (4.96e-2)" "unprognostic (4.13e-3)" "unprognostic (1.65e-1)" "unprognostic (1.44e-2)" "unprognostic (1.38e-3)" "unprognostic (5.88e-2)" "unprognostic (3.13e-2)" "unprognostic (6.20e-3)" "unprognostic (3.02e-1)" "unprognostic (5.31e-2)" "unprognostic (2.72e-2)" "unprognostic (2.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.44e-2)" "unprognostic (2.09e-1)" 2.4 3.1 1.4 1.4 1.9 1.0 3.8 2.6 2.7 3.4 2.5 1.9 1.0 4.2 3.7 2.3 4.2 3.2 1.8 1.4 1.8 3.6 1.5 3.3 1.7 1.3 1.3 5.3 2.4 5.4 2.2 3.3 0.6 4.3 2.0 5.7 2.9 3.6 1.4 2.3 1.1 3.2 0.3 2.3 2.2 4.8 2.5 6.3 6.9 3.3 1.7 2.7 1.4 2.8 5.7 3.5 8.4 6.4 11.4 10.3 3.7 5.8 4.2 6.6 5.2 4.0 7.6 1.4 3.7 5.2 10.4 2.7 2.4 3.5 6.5 3.8 2.6 3.3 21.9 2.4 5.8 0.0 1.8 7.8 4.7 6.7 3.5 7.8 6.5 3.6 0.0 1.2 11.8 0.0 4.2 4.8 2.2 0.0 2.7 4.0 14.9 0.0 6.0 1.7 4.7 3.3 48.7 0.3 3.1 6.8 2.6 3.5 8.0 10.0 6.2 2.7 4.5 1.7 0.0 1.6 2.4 0.1 3.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.3 0.0 0.0 1.4 1.9 2.6 2.7 1.4 1.8 1.3 1.3 0.6 0.3 2.5 2.8 19.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 11.3 8.9 0.0 0.0 0.0 22.0 0.0 7.4 8.8 0.0 0.0 8.8 0.0 50.3 42.9 4.8 0.0 0.0 0.0 5.3 5.8 7.6 0.0 20.6 0.0 40.8 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 2.6 0.0 0.0 3.9 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 3.6 3.2 18.9 0.0 0.0 CREB3L1 OASIS ENSG00000157613 "CAMP responsive element binding protein 3 like 1" Q96BA8 11 46277662-46321409 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 133.9;salivary gland: 83.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 89.2;Gastric mucus-secreting cells: 105.0;Glandular and luminal cells: 120.5;Intestinal goblet cells: 280.5" "Cancer enhanced" "Detected in all" "prostate cancer: 87.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 134.3;BJ hTERT+: 130.7;BJ hTERT+ SV40 Large T+: 120.6;fHDF/TERT166: 321.8;OE19: 129.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA024069, CAB026151" Enhanced NA NA "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB026151: , HPA024069: AB_1854750" "unprognostic (2.46e-2)" "unprognostic (2.80e-1)" "unprognostic (1.34e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.66e-3)" "unprognostic (2.93e-1)" "unprognostic (5.41e-2)" "unprognostic (2.75e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (1.54e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.97e-4)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (8.59e-4)" "unprognostic (1.12e-2)" 8.6 15.1 4.3 8.0 3.3 0.1 10.7 0.9 4.2 43.2 2.1 41.2 27.7 20.4 2.4 3.2 5.2 25.0 15.6 7.2 3.4 2.8 1.1 14.8 0.7 1.9 5.1 9.3 133.9 2.3 10.7 26.7 4.1 42.3 43.3 0.1 83.0 26.8 4.4 5.6 30.6 13.3 1.1 3.2 68.0 3.9 8.4 1.0 4.5 4.2 4.7 21.4 15.3 2.4 0.9 0.8 1.3 26.1 81.9 77.9 0.6 134.3 130.7 120.6 83.3 13.7 0.3 0.0 0.7 321.8 8.3 0.0 1.6 0.4 66.6 0.1 1.5 2.0 0.8 0.0 113.5 0.0 1.9 75.2 0.0 68.6 2.5 109.0 1.0 0.5 11.2 0.0 102.5 0.0 0.1 0.4 17.0 129.0 13.7 0.1 18.0 0.2 0.2 0.0 0.0 0.2 0.9 3.4 0.2 23.3 0.1 4.9 0.0 62.7 18.3 48.6 83.4 0.1 0.1 0.0 75.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 3.3 0.9 4.2 7.2 3.4 1.9 5.1 4.1 1.1 8.4 2.4 10.3 0.0 46.4 0.3 0.6 1.5 44.4 2.6 0.0 0.0 52.0 5.1 15.9 25.8 10.0 29.5 0.0 1.2 0.1 56.8 3.9 42.0 2.1 37.2 24.1 9.0 9.1 0.0 2.1 89.2 2.3 49.4 105.0 120.5 4.5 1.9 3.3 0.0 1.9 0.0 1.0 280.5 6.1 0.0 3.5 6.6 83.6 1.0 10.6 2.8 2.0 0.0 0.0 19.6 0.1 49.2 59.8 44.4 0.2 40.4 9.5 0.7 3.6 0.0 0.0 0.7 29.3 1.0 1.5 0.6 2.3 3.4 1.8 10.7 57.7 51.3 CREBBP "CBP, KAT3A, RSTS, RTS" ENSG00000005339 "CREB binding protein" Q92793 16 3725054-3880713 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004212, HPA055861" Supported Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Nuclear bodies" "CAB004212: AB_626817, HPA055861: AB_2682948" "unprognostic (1.17e-1)" "unprognostic (8.51e-2)" "unprognostic (1.60e-1)" "unprognostic (1.63e-1)" "unprognostic (1.49e-1)" "unprognostic (5.09e-2)" "unprognostic (9.59e-3)" "unprognostic (6.98e-2)" "unprognostic (8.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.76e-1)" "unprognostic (2.84e-1)" "prognostic favorable (6.24e-5)" "unprognostic (1.47e-1)" "unprognostic (1.74e-1)" "unprognostic (3.97e-2)" "unprognostic (8.23e-2)" 17.4 10.6 5.8 17.1 5.2 52.9 16.8 25.4 11.5 20.9 3.7 18.8 12.5 26.5 12.4 16.5 22.4 16.6 14.4 5.9 3.1 12.0 14.3 15.9 17.6 8.9 6.8 37.3 29.7 18.5 11.3 16.9 2.9 16.1 14.1 13.8 17.2 16.2 29.6 21.0 16.4 19.6 0.4 21.0 16.3 33.2 7.9 29.1 23.3 28.9 20.7 16.6 16.5 6.4 12.3 31.0 39.3 17.4 23.5 23.1 20.4 17.4 28.9 29.2 28.2 28.2 22.4 33.7 20.1 33.3 18.7 23.2 45.7 14.2 32.9 57.5 18.5 26.6 29.2 17.9 26.0 26.9 36.5 20.7 14.2 32.5 38.9 18.0 22.3 17.0 30.9 44.8 16.0 42.0 17.9 13.0 32.3 11.7 12.7 83.4 31.1 26.1 11.2 16.2 32.6 21.5 29.5 28.7 16.8 25.3 25.6 25.9 34.7 35.5 35.2 18.4 16.0 20.8 24.3 63.7 7.2 15.8 25.6 1.9 1.1 0.9 1.7 1.5 0.8 3.7 0.8 1.3 0.7 2.1 0.8 1.1 6.7 1.4 2.9 1.5 0.8 0.9 5.8 5.2 25.4 11.5 5.9 3.1 8.9 6.8 2.9 0.4 7.9 6.4 48.1 44.8 51.6 91.1 38.3 56.2 31.0 16.0 27.3 34.2 34.4 25.7 41.2 40.0 28.0 11.0 25.0 17.4 50.1 31.2 5.9 20.9 43.0 37.2 56.4 35.7 15.0 33.4 88.7 20.3 11.3 39.5 32.1 63.5 30.4 53.1 32.5 29.5 20.9 28.6 89.8 25.3 18.3 44.0 42.8 80.2 56.5 49.0 17.8 87.1 52.5 34.5 43.3 111.6 101.2 27.5 19.5 51.1 35.6 39.8 25.2 10.9 28.2 17.6 46.0 75.8 44.9 35.1 42.2 34.6 58.8 30.8 44.2 36.2 24.6 44.2 CRELD1 "AVSD2, CIRRIN" ENSG00000163703 "Cysteine rich with EGF like domains 1" Q96HD1 3 9933816-9945406 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 110.3;hTERT-RPE1: 77.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026964 Uncertain Approved Nucleoli,Cytosol "Intracellular and membrane" NA NA 19000000 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Nucleoli "HPA026964: AB_10602210" "unprognostic (3.06e-2)" "unprognostic (1.08e-1)" "unprognostic (2.69e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (8.07e-4)" "unprognostic (3.03e-1)" "unprognostic (3.59e-1)" "unprognostic (2.85e-2)" "unprognostic (1.24e-2)" "unprognostic (1.19e-1)" "unprognostic (1.92e-2)" "unprognostic (4.59e-2)" "unprognostic (1.14e-2)" "unprognostic (6.31e-2)" "unprognostic (9.51e-2)" "unprognostic (2.89e-1)" "unprognostic (3.78e-2)" 32.7 37.3 63.6 11.4 63.5 9.3 24.8 69.1 94.4 27.7 59.1 57.5 14.0 31.3 17.0 18.0 34.9 16.5 73.2 63.9 65.7 43.0 57.1 27.5 12.4 64.7 63.0 32.5 27.6 22.7 70.9 17.9 66.3 47.6 12.1 16.4 26.3 34.5 48.9 20.1 25.9 22.2 58.6 28.6 35.6 23.6 65.5 10.5 67.6 26.4 9.2 33.6 24.4 68.2 6.4 8.1 19.3 8.8 30.1 17.6 110.3 26.7 8.0 6.1 11.7 11.1 20.7 8.4 57.6 17.7 27.7 4.5 10.4 17.6 4.9 15.2 9.2 7.3 15.2 28.2 68.7 3.3 29.3 21.7 32.3 15.2 13.6 77.2 28.8 11.1 9.5 10.4 6.1 15.5 3.6 19.3 5.7 30.1 6.6 4.8 3.1 21.6 25.9 9.9 6.9 26.7 12.6 10.3 24.3 27.5 27.9 17.0 21.7 12.1 19.5 16.2 6.3 10.7 14.2 15.2 27.3 7.8 13.0 12.3 10.2 9.3 11.9 9.8 12.2 7.9 8.9 11.5 6.9 8.7 11.3 10.4 1.8 13.8 12.9 12.3 7.2 9.5 63.6 63.5 69.1 94.4 63.9 65.7 64.7 63.0 66.3 58.6 65.5 68.2 24.7 19.2 17.5 43.4 14.1 9.7 26.2 48.5 15.9 21.5 17.5 15.0 41.9 31.5 24.0 16.5 16.7 23.7 15.1 10.9 7.9 19.6 6.8 10.3 7.0 20.2 27.0 7.8 38.0 4.4 11.5 20.1 19.4 12.9 21.0 18.8 19.2 14.9 20.6 32.0 37.1 19.1 38.7 8.8 9.0 10.1 32.0 10.0 12.4 15.0 13.9 18.3 27.8 14.6 21.7 8.7 20.4 26.4 15.3 31.4 18.8 11.1 13.2 15.8 26.3 11.0 17.1 68.0 26.5 9.6 12.4 22.2 15.4 11.2 15.4 20.2 CRIPT HSPC139 ENSG00000119878 "CXXC repeat containing interactor of PDZ3 domain" Q9P021 2 46616416-46630176 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046080, HPA056765" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Nucleoli fibrillar center" "HPA046080: AB_2679529, HPA056765: AB_2683230" "unprognostic (3.38e-2)" "unprognostic (4.08e-1)" "unprognostic (1.67e-1)" "unprognostic (7.51e-3)" "unprognostic (1.91e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.10e-1)" "unprognostic (6.07e-2)" "unprognostic (1.54e-2)" "unprognostic (3.38e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (5.54e-4)" "unprognostic (4.18e-2)" "unprognostic (1.43e-1)" "unprognostic (1.12e-2)" "unprognostic (4.42e-2)" 7.0 7.7 4.7 2.2 4.6 6.0 6.6 7.6 6.0 5.9 5.3 7.2 3.0 5.9 5.5 6.3 5.5 1.8 11.9 4.8 4.1 7.2 6.1 4.3 3.3 5.5 4.3 7.2 5.4 2.7 6.0 2.1 5.0 5.6 2.8 10.7 7.0 1.9 12.3 6.1 5.6 2.2 3.6 4.7 6.3 5.8 4.6 2.4 4.7 2.8 3.1 6.3 6.3 7.8 3.8 2.5 2.3 2.4 2.7 2.9 3.4 2.7 1.8 1.7 1.7 2.9 2.7 2.9 5.7 2.9 2.4 2.6 2.3 2.4 3.3 4.4 2.6 3.6 3.4 3.8 3.1 2.8 2.2 3.3 2.9 2.4 1.7 3.2 2.7 1.6 3.7 3.4 2.1 2.4 1.9 3.5 3.0 3.6 2.5 1.7 4.6 4.4 3.2 2.7 4.2 6.7 3.1 2.4 3.2 2.3 2.0 2.1 3.5 2.7 2.6 2.7 3.0 3.7 3.1 2.8 4.1 3.1 2.3 6.3 2.6 3.8 2.9 2.3 2.6 3.6 3.0 2.6 2.1 3.5 3.0 2.9 5.8 3.0 2.4 3.2 3.6 1.9 4.7 4.6 7.6 6.0 4.8 4.1 5.5 4.3 5.0 3.6 4.6 7.8 28.6 19.2 13.7 19.2 34.5 43.1 65.5 71.3 28.5 28.9 56.5 54.4 60.4 45.8 51.8 31.3 25.0 56.7 48.4 38.5 68.4 64.5 41.8 46.4 33.7 29.5 65.1 91.8 22.5 39.8 81.4 35.1 20.4 37.7 28.5 28.3 38.6 57.5 48.1 16.8 25.7 39.9 42.7 38.9 30.2 15.9 36.4 29.3 30.2 20.6 48.7 40.4 51.5 44.2 31.2 67.6 58.4 25.6 46.2 58.6 81.0 102.6 48.7 51.2 19.7 26.0 48.0 56.0 49.6 39.1 53.0 95.6 35.8 26.2 32.6 74.9 CRLF1 "CISS, CISS1, CLF, CLF-1" ENSG00000006016 "Cytokine receptor like factor 1" O75462 19 18572220-18607741 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 88.5" "Cell type enhanced" "Detected in some" "Astrocytes: 15.3;Basal keratinocytes: 9.7;Fibroblasts: 16.0;Respiratory ciliated cells: 11.9;Skeletal myocytes: 19.9;Smooth muscle cells: 10.5" "Group enriched" "Detected in all" 4 "lung cancer: 27.4;thyroid cancer: 36.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "ASC diff: 1048.7;Hep G2: 458.8" "Region enriched" "Detected in many" 7 "hippocampal formation: 21.1" "Group enriched" "Detected in some" 6 "cerebellum: 2.3;spinal cord: 8.6" "HPA041493, HPA041793" Approved "Secreted in other tissues" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041493: AB_10795637, HPA041793: AB_10804117" "unprognostic (1.97e-1)" "unprognostic (2.29e-1)" "unprognostic (2.34e-3)" "unprognostic (9.31e-3)" "unprognostic (1.58e-2)" "unprognostic (1.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (4.69e-2)" "unprognostic (3.34e-3)" "unprognostic (4.95e-2)" "unprognostic (7.92e-2)" "prognostic unfavorable (3.96e-4)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.86e-2)" "unprognostic (5.27e-3)" 40.1 14.5 18.7 0.9 24.6 0.0 18.7 22.4 51.7 25.7 11.2 8.9 0.5 12.8 0.9 17.4 11.3 1.4 88.5 22.0 13.5 7.7 1.5 16.0 0.4 24.3 28.0 4.5 8.9 0.5 8.9 11.3 17.8 8.9 0.4 0.1 14.9 6.2 21.4 27.3 5.0 1.5 18.7 2.4 7.5 1.3 13.4 0.3 50.3 0.9 0.2 9.3 15.5 25.5 0.0 0.0 0.0 10.7 1048.7 15.3 5.2 5.4 0.0 0.0 0.0 0.1 0.0 0.0 66.5 33.2 1.9 0.4 10.8 0.2 0.0 0.0 1.4 0.0 18.1 458.8 7.5 0.1 0.5 12.0 1.0 0.2 0.3 1.6 0.3 0.0 0.1 0.2 0.3 16.6 0.0 0.0 1.2 0.1 0.3 0.0 9.1 0.1 0.0 0.5 0.0 0.1 14.2 0.0 0.0 2.0 13.0 0.6 1.3 0.1 11.1 0.8 0.4 0.1 0.0 0.5 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 24.6 22.4 51.7 22.0 13.5 24.3 28.0 17.8 18.7 13.4 25.5 0.4 0.0 0.0 15.3 0.3 9.7 0.6 6.8 0.0 0.2 0.7 4.2 2.5 0.0 2.6 0.0 0.0 0.1 0.3 0.1 5.9 0.3 6.9 2.6 1.9 0.5 0.0 0.0 7.8 0.2 1.3 16.0 0.5 0.5 0.0 0.2 0.4 0.1 0.3 0.0 1.0 0.0 2.0 0.0 1.0 0.4 0.0 0.4 0.0 0.0 0.1 0.9 1.0 0.5 0.8 0.2 0.0 0.0 0.0 0.3 0.0 0.3 11.9 1.3 0.0 19.9 10.5 0.2 2.2 0.6 4.5 0.3 0.6 0.2 0.1 0.3 CRTAP "CASP, LEPREL3, P3H5" ENSG00000170275 "Cartilage associated protein" O75718 3 33114014-33147773 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 377.6" "Group enriched" "Detected in all" 5 "dendritic cells: 306.9;monocytes: 377.6" "Cell line enhanced" "Detected in all" "ASC diff: 795.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043598, HPA044150" Approved Approved "Intermediate filaments,Actin filaments,Cytosol" "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Intermediate filaments, Actin filaments, Cytosol" "HPA043598: AB_10960991, HPA044150: AB_10959594" "unprognostic (5.29e-2)" "unprognostic (2.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.85e-3)" "unprognostic (7.36e-2)" "unprognostic (4.73e-3)" "unprognostic (4.28e-2)" "unprognostic (1.87e-1)" "unprognostic (9.97e-2)" "unprognostic (4.62e-2)" "unprognostic (3.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (9.93e-2)" "unprognostic (1.28e-3)" 157.2 106.5 65.2 38.7 69.2 43.2 123.9 51.9 54.8 211.2 52.9 145.1 35.0 170.1 57.1 58.7 138.3 80.5 83.9 49.6 64.9 67.9 44.6 92.3 37.3 65.2 62.4 131.4 36.0 45.7 22.8 69.9 63.9 90.7 51.6 19.3 54.0 106.5 54.4 84.1 65.6 115.0 67.5 48.2 78.9 25.0 65.3 23.7 77.2 68.9 38.1 142.7 135.8 69.5 64.1 123.3 37.8 119.2 795.0 516.6 219.0 136.1 294.0 160.6 151.9 42.1 35.1 44.4 147.6 259.3 129.9 80.2 68.0 103.9 115.5 110.1 106.0 69.2 87.6 43.7 237.4 45.4 54.8 415.3 208.5 145.0 183.2 311.7 172.0 27.0 60.3 82.1 164.6 54.7 16.5 46.3 45.5 67.5 165.7 59.4 111.0 86.1 127.8 42.0 7.9 61.0 92.0 79.8 201.1 87.3 85.9 109.3 113.0 209.1 89.1 115.4 145.9 59.0 214.3 6.7 164.3 89.7 117.1 13.4 377.6 28.5 35.8 147.7 52.5 39.9 51.4 40.2 306.9 39.2 29.2 27.8 30.5 42.1 46.0 82.5 74.0 200.5 65.2 69.2 51.9 54.8 49.6 64.9 65.2 62.4 63.9 67.5 65.3 69.5 74.0 9.6 42.8 15.3 29.0 60.4 41.1 39.5 150.8 17.9 32.7 43.7 34.7 25.8 22.0 38.6 8.4 49.0 37.1 14.8 11.7 25.0 1.2 17.4 135.7 72.7 6.0 46.0 10.0 32.0 81.6 142.3 29.0 31.2 48.1 58.4 122.4 53.2 107.0 35.3 14.5 26.0 10.2 181.1 91.1 6.3 142.9 108.6 80.0 10.3 134.1 15.9 22.6 17.1 11.6 18.4 16.3 144.8 58.1 24.5 24.4 52.7 6.8 10.1 111.7 78.4 120.9 1.6 15.9 95.1 46.7 28.0 26.5 89.9 36.1 30.0 CSPP1 "CSPP, CSPP-L, FLJ22490, JBTS21" ENSG00000104218 "Centrosome and spindle pole associated protein 1" Q1MSJ5 8 67062417-67196778 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 165.8;Endometrial ciliated cells: 177.6;Respiratory ciliated cells: 202.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056174 Supported "Centriolar satellite,Centrosome" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Centriolar satellite, Centrosome" "HPA056174: " "unprognostic (1.44e-1)" "unprognostic (8.23e-2)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" "unprognostic (4.70e-1)" "unprognostic (2.59e-2)" "unprognostic (5.24e-3)" "unprognostic (3.89e-2)" "unprognostic (7.85e-2)" "unprognostic (2.11e-1)" "unprognostic (1.30e-1)" "unprognostic (3.61e-2)" "unprognostic (9.29e-2)" "unprognostic (3.40e-1)" "unprognostic (9.46e-2)" "prognostic unfavorable (2.98e-4)" "unprognostic (2.93e-1)" 4.1 2.9 0.8 1.5 0.7 0.8 4.4 1.5 1.3 5.4 1.4 4.1 2.2 4.3 1.8 3.4 8.4 3.1 3.7 0.6 0.6 5.5 5.4 5.8 1.4 1.0 1.1 5.6 6.0 4.3 3.3 6.0 0.9 3.6 2.8 2.1 3.6 1.6 13.5 3.6 4.0 2.6 0.7 3.3 4.4 12.8 1.2 3.9 4.6 2.8 2.0 4.1 4.1 1.0 5.7 4.9 4.6 5.9 5.3 5.6 4.9 4.9 6.3 6.5 6.9 4.6 6.6 6.5 1.1 3.3 6.9 4.4 11.4 3.4 9.1 3.6 7.2 9.3 2.3 2.9 4.5 7.7 4.0 4.4 2.9 4.2 8.2 3.9 4.1 7.9 16.1 3.0 5.9 2.1 19.1 3.2 6.1 14.8 4.9 10.4 6.9 5.4 4.9 2.6 3.0 3.0 3.1 5.9 4.7 6.3 10.8 4.4 4.1 4.7 4.7 2.1 4.2 4.6 3.2 8.6 3.6 6.1 5.6 0.6 0.1 0.2 0.5 1.0 0.6 0.5 0.4 0.5 0.4 0.8 0.8 0.3 0.0 0.3 0.3 0.4 1.0 0.3 0.8 0.7 1.5 1.3 0.6 0.6 1.0 1.1 0.9 0.7 1.2 1.0 20.9 25.6 11.8 63.3 15.0 21.2 11.1 7.6 16.5 20.5 19.4 18.7 39.8 31.5 32.4 7.3 73.0 21.8 23.6 9.6 3.9 14.8 165.8 177.6 29.1 16.6 11.4 16.6 117.5 9.7 13.7 20.2 11.2 27.7 26.0 36.8 12.1 9.3 7.4 21.9 116.1 9.6 8.2 7.2 9.4 91.0 21.5 12.5 7.2 61.8 12.9 13.6 17.5 89.0 98.1 9.8 5.3 19.5 19.4 11.0 10.8 23.0 202.3 133.2 26.3 31.7 20.4 121.6 60.1 15.3 16.2 18.5 15.9 14.6 13.6 6.9 CST6 ENSG00000175315 "Cystatin E/M" Q15828 11 66012008-66013505 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "skin 1: 761.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 93.0;Club cells: 115.2;Pancreatic endocrine cells: 368.1;Respiratory ciliated cells: 404.0" "Group enriched" "Detected in many" 5 "thyroid cancer: 171.0;urothelial cancer: 43.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 130.2;CAPAN-2: 364.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB019316, HPA044963" Enhanced Approved "Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 82000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Cytosol "CAB019316: , HPA044963: AB_2679158" "unprognostic (3.01e-2)" "unprognostic (5.10e-2)" "unprognostic (1.14e-1)" "unprognostic (3.59e-2)" "unprognostic (5.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (5.02e-1)" "unprognostic (8.89e-3)" "unprognostic (1.29e-3)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (5.89e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-2)" "unprognostic (2.59e-2)" 3.2 0.3 0.1 0.3 0.1 0.2 28.5 0.8 0.4 7.4 0.8 0.4 0.0 0.3 0.6 34.6 14.9 0.5 2.8 0.1 0.3 2.6 0.3 18.3 0.0 0.2 0.2 0.7 0.7 2.1 1.6 8.1 0.1 0.9 0.0 0.0 7.4 4.9 2.0 761.4 0.3 0.1 0.1 0.2 0.6 1.8 0.4 2.7 21.4 0.0 2.2 1.2 22.5 0.2 130.2 0.0 0.0 0.6 0.0 0.0 37.6 1.4 0.0 0.3 0.2 1.0 364.6 0.0 1.8 5.1 0.1 4.5 0.0 32.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.8 0.6 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.5 0.5 0.8 0.2 0.7 0.0 0.0 35.8 0.4 0.1 0.8 0.1 0.0 0.2 2.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.8 0.4 0.1 0.3 0.2 0.2 0.1 0.1 0.4 0.2 0.1 93.0 6.1 0.0 0.6 1.1 1.7 41.4 0.6 0.0 5.3 7.1 1.2 0.0 115.2 58.8 0.0 33.3 0.0 0.1 0.0 57.4 0.2 7.7 0.1 0.9 0.0 0.0 0.0 21.6 24.4 2.0 0.0 0.6 21.6 0.1 0.4 0.1 41.1 0.0 0.0 0.0 24.4 1.4 10.0 0.8 0.0 5.3 5.4 0.0 1.1 1.3 0.0 0.0 0.0 368.1 1.1 0.4 9.8 1.9 0.0 0.5 404.0 0.1 0.0 0.3 16.0 5.2 17.6 1.0 27.6 64.2 0.7 0.0 0.4 6.1 CSTA "STF1, STFA" ENSG00000121552 "Cystatin A" P01040 3 122325248-122341969 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5912.9;vagina: 1853.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2493.8;Club cells: 768.0;Kupffer cells: 579.4;monocytes: 1298.6;Squamous epithelial cells: 3020.6" "Cancer enhanced" "Detected in all" "cervical cancer: 227.7;head and neck cancer: 405.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "classical monocyte: 514.7;intermediate monocyte: 269.1;myeloid DC: 382.9;neutrophil: 245.6;non-classical monocyte: 161.7" "Group enriched" "Detected in all" 193 "dendritic cells: 382.9;granulocytes: 245.6;monocytes: 514.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 282.0;hTCEpi: 1218.6;THP-1: 789.0;U-698: 504.5;U-937: 250.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000469, HPA001031, CAB047315" Enhanced Approved Nucleoplasm,Cytosol No No 28000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "CAB000469: , CAB047315: , HPA001031: AB_1078610" "unprognostic (5.22e-3)" "unprognostic (6.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.07e-2)" "unprognostic (7.79e-3)" "prognostic favorable (5.86e-4)" "unprognostic (4.46e-1)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (7.99e-2)" "unprognostic (2.56e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (8.89e-2)" "unprognostic (3.43e-2)" "unprognostic (9.24e-3)" "unprognostic (1.99e-1)" 30.7 4.7 0.8 27.1 0.9 297.8 56.3 1.0 3.7 961.0 1.4 3.8 1.1 2.2 10.3 5912.9 4.6 7.2 5.9 0.8 1.0 2.4 38.9 26.0 25.1 1.5 0.9 21.1 3.7 0.8 5.0 19.0 1.3 19.7 3.6 0.3 996.1 9.6 4.6 369.1 5.8 6.3 1.1 20.4 30.3 1.3 1.4 46.5 2.7 2.8 941.0 39.1 1853.3 1.6 14.6 1.3 0.2 3.2 31.5 58.0 2.9 0.6 0.8 0.0 0.0 0.0 0.0 3.2 7.6 5.9 0.5 86.9 0.0 282.0 0.0 0.3 0.2 0.7 0.0 6.8 6.8 117.6 1.9 30.5 1218.6 2.9 119.1 0.0 0.0 1.5 0.8 29.9 0.5 0.8 0.2 108.3 0.0 0.5 0.0 0.0 0.9 0.0 0.0 141.3 0.0 0.0 14.1 7.5 10.4 0.1 1.6 789.0 0.5 1.7 19.7 0.2 0.9 0.0 1.7 504.5 26.4 250.3 0.3 8.8 514.7 16.4 0.6 269.1 1.5 1.5 0.7 0.6 382.9 0.5 0.5 0.7 245.6 1.9 161.7 6.9 1.0 283.2 0.8 0.9 1.0 3.7 0.8 1.0 1.5 0.9 1.3 1.1 1.4 1.6 1.1 6.4 19.8 0.0 5.0 83.5 136.5 2493.8 117.8 0.0 7.1 119.8 0.2 2.8 768.0 0.0 0.0 230.6 7.4 3.9 0.0 2.1 0.4 0.3 0.4 3.0 0.0 3.8 0.1 22.1 17.8 13.6 12.8 0.3 13.9 0.1 6.1 96.0 134.5 0.0 0.1 0.5 179.0 579.4 90.6 2.4 10.2 243.7 8.8 0.0 1298.6 0.0 20.6 0.5 0.2 46.2 1.5 3.8 2.8 30.2 0.0 0.7 115.7 0.0 32.9 8.8 24.3 0.1 0.5 3020.6 205.0 334.2 4.9 26.1 2.0 134.1 CTDP1 FCP1 ENSG00000060069 "CTD phosphatase subunit 1" Q9Y5B0 18 79679803-79754510 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cataract, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 113.1;Late spermatids: 123.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032641, HPA040394, HPA070389" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Vesicles "CAB032641: AB_2261235, HPA040394: AB_10794029, HPA070389: AB_2732155" "unprognostic (1.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" "prognostic favorable (6.43e-4)" "unprognostic (2.64e-2)" "unprognostic (7.99e-2)" "unprognostic (3.47e-3)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (1.15e-1)" "unprognostic (5.21e-3)" "unprognostic (1.99e-2)" "prognostic favorable (5.51e-5)" "unprognostic (5.16e-2)" "unprognostic (8.58e-2)" "unprognostic (2.85e-2)" "unprognostic (4.74e-2)" 9.3 7.4 3.8 7.2 3.9 13.7 8.9 3.3 4.2 7.8 4.1 11.1 7.2 10.4 1.4 10.7 8.1 4.0 7.2 3.3 3.3 7.9 9.5 9.3 8.7 5.3 4.2 5.0 9.0 3.3 6.9 4.2 4.0 8.2 3.1 1.5 9.5 3.9 11.9 20.5 10.9 3.1 3.3 13.5 9.9 22.2 4.0 6.5 8.0 3.1 3.7 9.6 8.6 4.4 13.4 14.0 7.7 11.0 6.0 5.0 25.9 9.6 6.1 7.6 7.5 9.4 8.0 17.2 4.2 5.6 9.1 16.4 6.6 8.8 3.1 16.9 12.4 8.5 6.6 12.9 8.7 37.6 20.5 8.4 8.3 8.1 3.8 4.6 9.2 12.2 11.2 8.1 3.0 11.5 25.4 29.5 12.7 4.2 19.1 20.7 10.1 20.0 5.6 13.1 12.0 12.4 10.2 9.8 13.9 5.8 8.0 21.7 12.9 12.9 19.4 5.3 9.7 7.4 27.6 16.1 11.0 18.8 9.3 0.0 0.4 3.2 0.5 0.4 0.4 0.2 0.4 0.8 0.6 0.1 0.5 0.3 1.0 1.1 0.4 0.1 0.1 0.2 3.8 3.9 3.3 4.2 3.3 3.3 5.3 4.2 4.0 3.3 4.0 4.4 7.4 0.0 4.1 3.6 9.2 8.5 5.0 4.0 11.4 9.5 7.7 6.5 3.8 4.3 4.5 3.7 14.6 8.8 24.2 20.0 1.9 5.4 113.1 18.6 8.0 7.5 6.0 13.5 7.7 7.2 8.0 4.8 19.9 24.0 7.0 7.8 6.4 5.7 8.8 23.5 6.6 16.6 6.1 7.5 9.5 123.2 7.8 13.8 7.2 6.5 6.5 6.5 19.6 3.0 8.9 10.2 14.9 10.5 15.2 11.8 10.0 6.8 9.6 14.8 0.0 5.9 7.4 18.0 10.5 10.5 10.1 19.0 18.3 8.0 11.7 12.6 CTNNA2 "CAP-R, CT114" ENSG00000066032 "Catenin alpha 2" P26232 2 79185231-80648861 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Differentiation" "Developmental protein" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 99.0;epididymis: 67.0;retina: 80.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3673.8;Early spermatids: 560.8;Excitatory neurons: 1358.5;Inhibitory neurons: 1056.9;Oligodendrocyte precursor cells: 1304.4" "Group enriched" "Detected in some" 7 "endometrial cancer: 3.9;glioma: 11.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 96 "basophil: 55.3" "Lineage enriched" "Detected in single" 553 "granulocytes: 55.3" "Cell line enhanced" "Detected in some" "AF22: 7.1;Karpas-707: 8.2;NTERA-2: 6.7;SCLC-21H: 3.8;SH-SY5Y: 10.7" "Low region specificity" "Detected in all" CAB037175 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "CAB037175: AB_476883" "unprognostic (9.15e-2)" "unprognostic (2.26e-2)" "unprognostic (2.66e-1)" "unprognostic (1.24e-2)" "unprognostic (1.16e-1)" "unprognostic (1.23e-1)" "unprognostic (3.31e-2)" "unprognostic (4.04e-1)" "unprognostic (3.17e-2)" "unprognostic (5.62e-2)" "unprognostic (7.96e-3)" "unprognostic (8.76e-2)" "unprognostic (2.27e-4)" "unprognostic (7.80e-2)" "unprognostic (8.44e-4)" "unprognostic (1.73e-4)" "unprognostic (2.83e-1)" 0.1 4.7 74.1 0.5 82.5 0.1 0.0 51.8 99.0 0.4 28.5 1.9 0.3 3.3 67.0 0.2 1.9 0.2 0.2 78.8 59.3 0.1 0.1 0.0 0.0 47.0 71.2 0.1 0.8 0.0 7.1 0.0 50.8 1.0 0.9 80.4 0.2 0.7 0.2 0.1 0.7 0.5 36.6 0.0 1.1 17.4 78.9 0.0 0.0 0.0 0.0 0.1 0.4 62.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 6.7 0.3 0.0 0.0 0.0 0.0 0.7 0.0 3.8 10.7 0.0 0.0 0.5 1.0 0.0 0.6 0.0 0.4 0.7 0.2 0.0 2.3 0.0 0.0 2.7 0.0 2.0 55.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 74.1 82.5 51.8 99.0 78.8 59.3 47.0 71.2 50.8 36.6 78.9 62.0 0.0 0.0 0.0 3673.8 0.0 0.0 0.0 0.0 0.0 17.2 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 560.8 12.9 7.0 0.5 0.0 0.0 1358.5 0.0 0.0 0.1 0.0 34.3 0.0 4.7 0.0 0.0 0.0 5.0 1056.9 0.0 0.0 0.0 0.0 144.4 2.5 0.5 0.0 187.4 0.0 112.1 0.0 1304.4 230.7 0.3 0.0 3.0 0.0 0.0 0.0 0.2 0.0 5.0 0.0 0.0 0.2 10.3 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.1 CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.9;intermediate monocyte: 9.5;myeloid DC: 6.3;non-classical monocyte: 5.6" "Group enriched" "Detected in many" 19 "dendritic cells: 6.3;monocytes: 9.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" 72.6 48.8 29.6 34.8 28.1 5.9 83.3 28.2 33.0 86.0 50.0 107.9 97.8 70.8 49.3 209.7 58.4 56.3 49.0 26.6 26.8 77.9 82.6 83.9 19.0 34.8 30.6 49.3 120.0 76.1 57.7 106.0 32.5 78.9 102.0 23.5 121.8 57.1 26.8 129.4 104.9 54.8 32.3 51.5 105.4 44.3 38.0 24.4 98.6 19.9 48.4 83.5 111.9 33.5 156.6 106.4 70.2 63.3 46.1 71.6 141.7 65.1 78.8 58.5 55.6 88.5 163.9 1.0 113.2 72.5 50.9 201.7 58.8 97.4 71.1 1.0 21.9 32.0 35.8 109.9 52.6 5.0 52.7 70.0 133.5 67.1 73.5 103.8 197.2 1.7 55.1 0.4 55.1 48.0 1.7 13.9 54.7 101.2 56.5 0.7 67.4 1.3 90.2 171.0 4.9 40.1 91.5 133.6 113.1 176.3 138.9 6.1 166.0 59.6 50.3 53.2 34.6 1.2 0.9 2.3 53.2 3.4 111.5 0.0 4.9 0.1 0.0 9.5 0.2 0.2 0.0 0.1 6.3 0.3 0.0 0.0 0.2 0.4 5.6 1.4 0.1 1.1 29.6 28.1 28.2 33.0 26.6 26.8 34.8 30.6 32.5 32.3 38.0 33.5 116.2 147.4 84.0 0.0 8.8 117.1 96.9 82.9 126.9 21.0 101.5 70.5 17.5 125.8 96.6 141.6 39.6 94.0 2.3 305.5 13.7 106.7 14.1 91.1 58.5 98.6 86.2 21.3 0.0 97.2 85.6 34.5 165.1 139.4 32.4 61.1 91.8 127.6 44.4 15.2 0.0 160.7 52.9 64.3 55.5 10.5 28.3 46.4 48.0 0.0 28.5 30.2 2.1 0.0 0.0 141.8 169.3 38.4 5.0 116.9 179.6 57.6 88.2 26.4 26.3 32.3 38.1 37.0 21.1 285.1 200.5 90.8 6.2 39.9 127.0 194.6 CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88265069-88359684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 900.7;Club cells: 471.8;Hofbauer cells: 1100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" No No 19000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB025364: , HPA066610: AB_2685694, HPA068434: AB_2685989" "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (9.30e-5)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-2)" "unprognostic (3.35e-1)" "prognostic favorable (4.80e-4)" "unprognostic (2.93e-1)" "unprognostic (4.35e-2)" "unprognostic (8.10e-2)" "unprognostic (4.07e-2)" 173.2 60.7 9.9 185.1 9.6 71.7 63.4 11.1 24.9 77.9 14.2 143.1 121.0 43.9 28.5 63.3 54.0 182.0 38.5 9.5 10.1 234.7 82.0 272.6 243.7 14.0 11.9 22.1 52.2 42.4 39.3 253.3 13.3 26.0 191.5 3.7 131.6 28.9 18.8 29.6 128.8 88.9 11.5 197.2 73.6 22.8 19.5 63.7 43.6 31.9 140.6 176.3 43.3 21.3 80.3 75.9 27.6 69.9 103.7 286.1 218.4 626.5 1078.4 372.8 270.3 194.7 361.3 117.3 278.9 365.2 84.3 133.6 50.4 269.2 341.9 204.7 82.8 144.5 188.0 233.5 140.2 188.9 108.7 419.1 198.8 284.5 697.4 302.1 377.6 122.3 155.3 145.4 54.8 14.8 89.1 295.1 172.2 551.5 244.9 113.6 30.7 227.0 451.3 106.6 8.8 66.8 81.2 114.9 80.6 185.4 27.9 152.7 149.3 23.5 190.5 156.8 364.6 61.9 81.0 122.9 56.8 435.8 122.4 85.5 203.8 309.7 230.1 415.6 194.9 47.2 99.6 198.2 209.9 26.3 49.5 115.3 215.0 200.5 582.9 425.0 162.7 243.3 9.9 9.6 11.1 24.9 9.5 10.1 14.0 11.9 13.3 11.5 19.5 21.3 78.6 22.4 88.1 0.3 40.8 30.1 7.3 900.7 33.6 1.5 15.9 14.6 4.4 52.9 471.8 40.5 0.0 414.1 330.6 37.9 29.4 29.8 1.6 13.4 135.6 94.8 11.4 29.7 3.0 90.6 159.2 114.4 39.8 21.2 75.3 25.5 26.4 15.8 1100.6 0.0 8.2 19.4 158.7 344.7 200.7 7.9 198.5 391.7 48.0 61.8 185.4 0.5 299.7 13.6 0.4 44.8 72.3 25.6 78.5 8.5 20.2 166.4 93.7 0.8 59.2 4.4 150.8 3.0 11.1 43.3 27.1 227.3 170.6 286.7 44.9 16.1 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTU2 "C16orf84, NCS2" ENSG00000174177 "Cytosolic thiouridylase subunit 2" Q2VPK5 16 88706483-88715396 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041135, HPA041894" Uncertain Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041135: AB_10794543, HPA041894: AB_10796463" "unprognostic (4.19e-1)" "unprognostic (3.62e-2)" "unprognostic (5.19e-2)" "unprognostic (5.77e-2)" "unprognostic (3.00e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (4.83e-2)" "unprognostic (1.56e-1)" "unprognostic (4.43e-2)" "unprognostic (1.19e-3)" "unprognostic (2.90e-2)" "unprognostic (1.25e-2)" "unprognostic (3.03e-2)" "unprognostic (5.83e-2)" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" 9.7 9.6 8.8 5.0 8.7 6.2 8.8 7.9 13.8 10.2 6.5 9.9 4.2 11.6 2.0 8.7 9.5 3.5 11.8 9.1 7.5 9.7 12.5 7.9 6.1 9.6 8.1 10.5 11.3 3.6 11.3 3.2 8.5 8.8 1.6 1.4 8.0 3.7 19.1 8.7 7.6 3.4 7.5 9.4 9.6 10.9 8.2 4.0 10.3 5.4 3.4 9.9 8.1 10.5 14.9 22.9 8.8 19.4 7.3 7.5 21.8 15.2 11.4 16.6 8.1 27.2 14.0 21.7 19.8 9.8 7.8 14.7 14.8 14.9 4.5 6.8 44.6 14.9 9.8 27.8 12.4 15.1 10.8 8.5 10.8 13.1 13.9 6.0 14.1 13.1 56.5 6.3 6.3 40.0 42.0 34.9 13.7 12.9 36.9 33.0 6.6 23.4 5.8 5.8 29.0 14.0 24.2 4.6 9.7 5.3 13.8 15.6 15.9 17.5 22.1 19.2 16.8 19.4 10.5 61.7 15.1 32.1 19.6 1.1 5.5 0.0 7.3 6.9 6.0 5.5 6.6 7.3 6.8 5.8 6.4 5.5 0.4 7.5 6.0 6.4 4.1 4.2 8.8 8.7 7.9 13.8 9.1 7.5 9.6 8.1 8.5 7.5 8.2 10.5 6.5 0.0 4.4 2.3 10.0 13.8 12.2 7.8 5.2 12.5 7.3 7.2 2.5 10.0 7.8 1.8 6.2 11.0 15.7 8.4 11.7 8.8 12.1 4.0 7.1 6.6 5.4 3.8 2.9 13.6 16.2 8.6 11.2 4.9 0.0 9.9 3.6 6.7 9.9 13.5 2.3 7.1 4.1 1.9 4.0 7.0 8.1 6.7 5.4 1.0 5.0 4.4 7.2 0.5 2.7 8.9 8.2 9.8 15.5 17.2 9.6 7.8 4.7 8.7 0.0 8.9 11.1 25.6 25.7 6.5 10.7 8.1 9.5 10.8 10.5 8.9 CUL7 "dJ20C7.5, KIAA0076" ENSG00000044090 "Cullin 7" Q14999 6 43037617-43053943 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015449, HPA030095, HPA030096" Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 51: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 52: Non-specific - Transcription" "CAB015449: AB_629341, HPA030095: AB_10600659, HPA030096: AB_10600997" "unprognostic (2.32e-2)" "unprognostic (4.79e-2)" "unprognostic (1.01e-3)" "unprognostic (6.06e-2)" "unprognostic (5.41e-3)" "unprognostic (4.95e-2)" "unprognostic (3.72e-2)" "unprognostic (1.94e-2)" "unprognostic (1.01e-1)" "unprognostic (9.81e-2)" "unprognostic (2.13e-3)" "unprognostic (4.81e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (8.92e-2)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (3.35e-1)" 7.5 13.7 5.0 6.6 5.0 4.4 8.8 5.7 5.3 14.4 7.9 7.6 7.7 11.7 9.0 6.9 14.2 7.6 5.9 5.4 7.0 11.0 9.7 7.4 6.2 3.8 4.4 15.9 15.7 6.9 26.0 10.2 4.9 11.0 5.4 5.5 8.5 8.7 13.2 7.5 8.0 9.2 3.5 9.7 9.4 5.7 6.9 6.1 12.9 10.7 5.4 8.9 9.6 4.0 10.6 8.2 27.1 32.0 27.9 40.7 2.2 15.7 21.0 18.8 19.0 18.0 7.9 4.9 35.2 27.0 19.1 3.9 9.9 13.9 8.8 12.4 10.5 12.2 9.1 25.5 23.2 4.4 14.2 42.5 13.1 16.2 17.4 33.7 18.0 5.6 10.7 12.3 24.1 21.8 5.6 10.9 4.5 32.2 6.7 9.1 6.5 12.7 16.6 14.4 14.6 18.2 12.2 11.3 11.1 12.4 16.6 8.3 18.9 28.1 12.0 9.1 6.9 25.6 7.0 12.9 11.2 4.8 16.5 0.0 0.7 0.4 0.6 0.6 0.4 0.5 0.4 0.2 0.7 0.7 0.2 0.4 0.2 0.6 0.5 0.9 0.3 0.6 5.0 5.0 5.7 5.3 5.4 7.0 3.8 4.4 4.9 3.5 6.9 4.0 3.9 6.4 10.5 6.5 4.5 2.5 1.7 5.2 4.0 6.0 7.2 6.0 4.6 1.5 4.6 3.7 6.2 4.8 1.7 3.8 0.0 6.4 0.6 8.4 7.7 5.8 7.2 2.1 6.0 4.8 3.7 6.9 10.7 6.3 4.5 15.9 5.7 2.2 5.0 1.7 5.9 8.2 6.1 2.2 1.8 0.2 9.3 2.7 1.8 5.6 1.2 4.1 1.0 3.0 3.1 4.6 2.6 7.5 3.9 2.2 6.4 4.9 12.9 7.8 0.0 7.5 4.9 0.8 2.5 4.2 1.7 4.4 2.8 17.3 4.6 1.5 CWC27 "NY-CO-10, SDCCAG-10, SDCCAG10" ENSG00000153015 "CWC27 spliceosome associated cyclophilin" Q6UX04 5 64768930-65018750 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Dwarfism, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 255.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020344, HPA024149, HPA065809" Approved Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA020344: AB_1856644, HPA024149: AB_1856645, HPA065809: AB_2685561" "unprognostic (1.71e-1)" "unprognostic (6.47e-3)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (8.91e-2)" "unprognostic (4.00e-3)" "prognostic unfavorable (5.27e-6)" "unprognostic (1.58e-2)" "unprognostic (3.43e-2)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.46e-1)" "unprognostic (2.05e-1)" "unprognostic (2.74e-1)" "unprognostic (7.45e-3)" 13.4 13.0 13.6 13.0 14.6 20.5 13.4 16.7 18.4 12.6 10.7 14.3 9.8 15.5 12.3 11.8 11.8 11.2 18.9 13.1 15.5 14.1 10.2 10.7 15.4 14.5 13.7 18.2 9.0 16.9 8.8 14.6 14.4 13.9 15.0 14.0 10.5 12.3 22.2 11.5 10.1 14.3 13.5 12.8 11.1 17.2 14.1 21.7 13.9 26.4 16.0 13.2 11.5 15.4 32.7 21.4 37.5 69.9 31.4 38.2 41.8 33.5 27.7 36.7 38.2 36.0 40.3 48.0 57.0 35.0 41.2 20.2 39.8 60.5 66.2 40.4 32.4 36.2 35.6 30.3 48.0 38.3 23.5 25.6 45.7 46.3 58.3 32.3 39.4 53.9 35.8 30.8 36.8 32.6 53.5 34.7 30.4 16.9 25.6 49.0 50.4 50.3 35.0 28.0 44.4 19.6 40.8 16.4 39.7 35.5 35.9 55.5 32.9 21.4 37.8 34.6 54.2 23.9 33.1 46.5 40.1 65.9 38.8 13.2 13.1 9.6 13.6 13.2 16.8 17.5 15.3 17.4 16.9 13.2 16.2 16.9 2.7 20.4 10.2 13.8 18.0 10.4 13.6 14.6 16.7 18.4 13.1 15.5 14.5 13.7 14.4 13.5 14.1 15.4 24.2 9.6 26.2 64.3 26.0 16.4 27.7 37.5 13.6 31.4 17.4 20.3 63.6 18.6 23.2 14.7 14.6 44.0 16.8 11.6 21.5 44.1 255.6 21.0 27.2 27.2 29.9 37.8 114.1 33.1 54.5 25.1 13.7 20.2 19.6 40.7 16.4 11.4 33.0 20.2 110.3 17.0 40.7 17.1 15.2 57.9 38.5 22.3 14.2 61.8 33.6 34.2 36.0 103.0 103.2 40.4 16.0 36.1 21.0 22.1 13.3 24.4 28.6 51.3 32.9 31.3 33.6 74.2 28.3 20.6 20.0 30.8 26.2 30.7 28.6 23.8 CYP1B1 "CP1B, GLC3A" ENSG00000138061 "Cytochrome P450 family 1 subfamily B member 1" Q16678 2 38066973-38109902 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Disease variant, Glaucoma, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 170.8;Prostatic glandular cells: 747.6;Urothelial cells: 498.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "classical monocyte: 156.9" "Lineage enriched" "Detected in many" 24 "monocytes: 156.9" "Cell line enhanced" "Detected in many" "ASC diff: 128.7;ASC TERT1: 136.8;HSkMC: 551.3;hTERT-RPE1: 128.9;SiHa: 270.0;U-87 MG: 142.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 34.6" "CAB011705, HPA026863" Approved Uncertain Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB011705: AB_731810, HPA026863: AB_10600900" "unprognostic (7.25e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.68e-1)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (9.69e-2)" "unprognostic (4.20e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.87e-3)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "prognostic unfavorable (2.76e-4)" 28.4 12.0 2.7 31.9 6.2 2.0 29.4 1.6 8.9 34.9 10.4 3.7 2.2 41.0 19.5 7.6 44.9 23.8 29.2 2.5 2.3 24.1 7.0 16.8 11.6 3.6 2.9 5.6 7.2 0.9 14.8 4.5 3.0 34.7 2.1 1.2 4.3 39.2 3.4 6.3 5.8 35.1 3.6 27.3 15.9 8.0 7.3 28.3 8.7 5.5 1.9 35.0 6.7 1.5 7.0 71.9 2.3 0.0 128.7 136.8 0.4 0.6 4.4 1.3 12.3 0.2 30.1 0.0 19.1 17.8 3.1 58.7 0.3 4.0 2.3 5.5 3.8 0.0 21.2 0.0 36.0 0.2 0.1 551.3 55.3 30.7 1.4 128.9 0.0 0.3 0.7 0.2 0.7 29.2 0.3 22.5 7.5 10.4 14.2 0.1 0.0 0.2 13.4 0.9 0.5 2.1 270.0 38.8 0.0 7.5 49.4 10.8 0.0 1.1 0.2 107.9 0.1 0.3 0.2 0.0 142.2 0.1 11.8 1.6 156.9 0.0 0.1 23.2 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.1 6.5 0.1 18.6 0.7 0.1 70.2 2.7 6.2 1.6 8.9 2.5 2.3 3.6 2.9 3.0 3.6 7.3 1.5 56.8 19.2 66.3 0.0 1.7 17.7 118.4 86.9 8.0 0.7 18.3 42.0 3.4 0.0 79.7 46.0 0.0 0.3 1.1 0.9 15.6 6.0 15.1 11.7 100.4 103.8 1.8 0.0 4.5 0.5 0.8 114.1 3.6 28.2 3.8 0.1 7.5 12.2 12.6 0.0 0.3 1.3 4.1 103.0 50.6 12.1 159.7 112.2 17.8 64.6 140.1 1.6 3.1 0.0 0.2 0.6 0.1 170.8 0.3 747.6 0.1 1.6 11.2 0.5 19.7 4.5 32.7 12.6 2.6 2.4 14.2 0.3 2.4 1.3 1.0 498.7 CYP26C1 ENSG00000187553 "Cytochrome P450 family 26 subfamily C member 1" Q6V0L0 10 93060798-93069540 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Ectodermal dysplasia" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.2;Microglial cells: 2.8;Rod photoreceptor cells: 1.0;Theca cells: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (8.39e-2)" "unprognostic (3.41e-2)" "unprognostic (3.88e-1)" "unprognostic (5.05e-2)" "unprognostic (3.25e-2)" "unprognostic (3.43e-2)" "unprognostic (4.97e-2)" "unprognostic (1.70e-1)" "unprognostic (8.85e-2)" "unprognostic (5.29e-2)" "unprognostic (2.47e-1)" "unprognostic (1.10e-1)" "unprognostic (2.02e-2)" "unprognostic (1.74e-4)" "unprognostic (8.59e-3)" "unprognostic (3.10e-3)" "unprognostic (1.17e-1)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 6.9 0.0 0.0 CYP4F22 FLJ39501 ENSG00000171954 "Cytochrome P450 family 4 subfamily F member 22" Q6NT55 19 15508525-15552317 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" Ichthyosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.8;skin 1: 58.6;vagina: 22.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.8;Breast myoepithelial cells: 5.5;granulocytes: 7.0;Prostatic glandular cells: 4.0;Suprabasal keratinocytes: 3.0" "Group enriched" "Detected in many" 7 "breast cancer: 4.5;head and neck cancer: 5.7;liver cancer: 8.5;melanoma: 4.5;urothelial cancer: 13.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "intermediate monocyte: 6.1;MAIT T-cell: 4.3;non-classical monocyte: 14.1" "Group enriched" "Detected in many" 8 "monocytes: 14.1;T-cells: 4.3" "Cell line enhanced" "Detected in some" "MCF7: 1.7;T-47d: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA058960 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" "HPA058960: AB_2683862" "unprognostic (2.32e-3)" "unprognostic (1.17e-2)" "unprognostic (6.81e-2)" "unprognostic (2.47e-2)" "unprognostic (1.03e-1)" "unprognostic (7.02e-2)" "unprognostic (1.30e-1)" "unprognostic (2.43e-1)" "unprognostic (3.33e-1)" "unprognostic (1.89e-2)" "unprognostic (9.33e-2)" "unprognostic (3.00e-2)" "unprognostic (2.21e-5)" "unprognostic (8.10e-2)" "unprognostic (3.16e-1)" "unprognostic (7.25e-3)" "unprognostic (2.03e-2)" 1.3 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 10.5 0.0 0.0 0.2 0.3 0.0 18.8 0.1 0.1 0.0 0.0 0.0 0.0 7.0 0.3 0.3 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 3.2 6.4 0.2 58.6 0.1 0.0 0.0 0.3 1.4 1.0 0.0 0.1 0.0 0.0 1.7 6.3 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 6.1 4.3 0.0 0.5 1.5 0.2 0.0 0.0 0.4 0.0 1.1 14.1 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 8.8 5.5 0.4 1.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.0 0.1 0.0 0.0 7.0 0.0 0.0 1.5 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.4 0.0 0.3 0.0 0.0 0.5 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.1 4.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.8 0.0 3.0 0.0 1.8 0.0 0.0 0.3 DCAF17 "C2orf37, FLJ13096" ENSG00000115827 "DDB1 and CUL4 associated factor 17" Q5H9S7 2 171434217-171485052 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Deafness, Diabetes mellitus, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 56.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053339, HPA055040" Uncertain Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA053339: AB_2682119, HPA055040: AB_2682680" "unprognostic (1.60e-2)" "unprognostic (1.21e-1)" "unprognostic (4.05e-1)" "unprognostic (1.03e-2)" "unprognostic (1.60e-1)" "unprognostic (5.98e-2)" "unprognostic (5.60e-2)" "unprognostic (2.67e-2)" "unprognostic (2.30e-3)" "unprognostic (2.08e-2)" "unprognostic (1.45e-1)" "unprognostic (1.69e-1)" "unprognostic (1.12e-2)" "unprognostic (1.41e-1)" "unprognostic (4.27e-1)" "prognostic unfavorable (7.10e-4)" "unprognostic (2.79e-2)" 3.9 4.5 5.2 5.4 6.6 3.4 6.4 6.6 6.1 6.1 4.3 5.6 4.5 6.2 6.3 4.4 4.6 3.8 3.5 5.1 5.7 5.6 4.5 3.8 7.2 5.5 5.2 7.1 5.0 6.0 3.8 5.3 5.8 5.0 4.6 13.9 4.3 4.5 3.9 7.2 4.7 4.6 5.5 6.4 4.4 5.7 6.9 7.8 10.2 4.3 6.0 5.6 5.4 10.6 8.5 6.9 8.9 10.6 11.0 11.7 13.6 7.3 7.5 7.3 6.8 8.3 5.5 24.4 5.4 9.1 5.5 8.2 9.1 9.0 9.9 11.4 6.2 11.3 6.2 15.0 11.2 16.2 7.9 9.2 11.6 9.3 20.7 8.6 8.0 7.6 17.9 8.2 10.1 5.2 17.9 14.9 13.2 6.2 4.3 13.4 11.7 13.4 6.2 7.6 7.8 11.3 6.9 5.8 7.4 8.3 4.5 8.3 9.6 8.4 7.6 4.8 6.4 12.4 18.3 20.5 8.9 8.2 8.8 1.1 1.3 0.5 2.3 1.5 3.4 1.3 1.8 1.7 1.0 1.8 2.0 2.5 0.0 1.1 1.3 0.8 1.8 1.6 5.2 6.6 6.6 6.1 5.1 5.7 5.5 5.2 5.8 5.5 6.9 10.6 5.8 0.0 7.5 17.9 8.9 4.7 4.7 4.2 8.6 10.1 7.8 6.0 5.0 7.2 3.1 7.3 12.5 6.5 6.0 4.4 9.8 4.8 2.2 6.2 10.7 5.2 10.2 6.9 18.0 3.9 5.7 5.8 8.2 4.9 3.8 8.2 2.5 7.7 5.6 8.4 23.5 4.5 6.1 8.4 4.6 3.6 6.2 5.0 3.6 15.0 4.4 8.8 5.2 24.6 56.5 6.6 2.0 6.0 6.4 6.3 5.5 6.2 6.1 15.2 0.0 6.7 7.2 13.5 17.1 8.7 5.1 5.6 7.5 9.0 4.3 5.0 DCDC2 "DCDC2A, DFNB66, KIAA1154, NPHP19, RU2" ENSG00000146038 "Doublecortin domain containing 2" Q9UHG0 6 24171755-24358059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Neurogenesis" "Ciliopathy, Deafness, Disease variant, Nephronophthisis, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.1;kidney: 23.2;pancreas: 26.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 62.9;Collecting duct cells: 79.1;Distal tubular cells: 56.7;Ductal cells: 135.9;Endometrial ciliated cells: 160.3;Glandular and luminal cells: 102.4;Proximal tubular cells: 54.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 71.8;EFO-21: 48.3;Hep G2: 82.3;RPTEC TERT1: 254.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA031582, HPA031583, HPA031584" Enhanced Supported "Microtubules,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Cytosol "Microtubules, Mitotic spindle, Centriolar satellite" "HPA031582: AB_10600901, HPA031583: AB_2673944, HPA031584: AB_2673945" "unprognostic (8.65e-2)" "unprognostic (2.07e-2)" "unprognostic (1.66e-1)" "unprognostic (6.70e-2)" "unprognostic (1.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.09e-1)" "unprognostic (2.67e-2)" "unprognostic (5.22e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-2)" "unprognostic (2.99e-2)" 0.0 1.3 0.8 0.0 1.2 0.1 4.4 0.3 0.8 1.6 15.1 0.7 0.6 4.4 5.3 0.0 7.6 3.9 0.0 0.8 1.0 23.2 2.2 3.4 0.0 2.2 2.7 0.2 26.2 8.2 1.2 0.6 1.7 1.2 0.6 1.4 0.4 2.3 0.3 0.1 0.1 0.1 2.0 0.1 1.8 3.7 1.1 0.1 8.2 0.2 0.0 0.4 0.0 1.6 0.0 8.8 0.5 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 71.8 0.2 0.0 48.3 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.2 0.0 0.0 82.3 0.0 0.0 0.0 0.0 0.0 9.7 0.0 1.4 0.0 0.2 0.1 0.0 0.3 10.8 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 254.5 0.3 5.2 0.5 0.0 1.3 0.0 0.2 12.3 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.5 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.8 1.2 0.3 0.8 0.8 1.0 2.2 2.7 1.7 2.0 1.1 1.6 0.2 19.2 14.4 3.9 1.4 0.1 0.6 0.3 0.0 0.0 20.3 11.7 0.3 62.9 6.1 79.1 0.0 0.4 0.0 1.2 56.7 135.9 40.1 160.3 5.3 0.4 3.6 0.0 11.3 8.4 0.0 1.3 3.6 102.4 0.0 4.1 0.0 1.0 0.5 0.0 8.3 2.9 0.0 0.0 0.0 14.6 0.3 1.0 0.0 1.0 2.0 2.3 0.0 1.0 0.5 27.9 4.1 0.4 0.0 1.3 0.0 54.3 37.1 0.1 0.0 0.0 2.4 32.3 2.6 0.0 0.1 0.1 1.1 5.6 2.7 0.9 DCHS1 "CDH25, CDHR6, FIB1, FLJ11790, KIAA1773, PCDH16" ENSG00000166341 "Dachsous cadherin-related 1" Q96JQ0 11 6621330-6655809 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 34.8;Endometrial stromal cells: 17.3;Endothelial cells: 29.0;Fibroblasts: 17.0;Granulosa cells: 19.3;Hepatic stellate cells: 61.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 33.5;HUVEC TERT2: 47.1;REH: 23.5;SH-SY5Y: 32.4;TIME: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017970, HPA050246" Approved Approved "Plasma membrane" NA NA 4000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA017970: AB_2669718, HPA050246: AB_2681062" "unprognostic (2.42e-1)" "unprognostic (1.13e-1)" "unprognostic (8.93e-2)" "unprognostic (3.52e-2)" "unprognostic (1.83e-1)" "unprognostic (1.38e-3)" "unprognostic (2.52e-2)" "unprognostic (4.55e-3)" "unprognostic (2.63e-2)" "unprognostic (2.93e-2)" "unprognostic (5.96e-2)" "unprognostic (6.87e-2)" "prognostic unfavorable (9.32e-4)" "unprognostic (5.62e-2)" "unprognostic (2.28e-1)" "unprognostic (1.60e-2)" "unprognostic (1.24e-3)" 9.4 2.5 7.4 8.4 6.8 0.7 9.3 6.1 6.3 19.5 0.9 19.0 4.1 28.9 2.4 5.0 13.2 8.3 9.2 6.6 10.1 4.6 2.0 10.1 4.0 7.6 6.3 11.6 3.3 2.0 3.2 10.1 5.7 9.3 3.4 0.6 3.5 11.5 4.2 3.7 8.3 16.2 4.7 12.9 8.2 3.0 8.7 3.8 4.1 4.6 2.2 14.8 9.3 3.8 0.0 0.1 33.5 0.1 0.0 0.1 0.3 1.2 8.7 5.4 6.0 0.3 0.0 0.1 5.1 9.9 0.4 0.0 2.7 0.1 3.7 0.1 0.9 0.7 0.0 0.0 0.3 0.2 0.0 1.0 0.1 2.5 0.0 0.0 47.1 0.1 0.2 0.0 2.0 0.0 1.2 0.6 5.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 2.4 32.4 0.0 0.3 0.2 3.5 0.0 1.3 20.4 0.1 10.0 0.1 0.0 0.1 0.0 0.1 0.3 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 7.4 6.8 6.1 6.3 6.6 10.1 7.6 6.3 5.7 4.7 8.7 3.8 34.8 0.0 0.5 12.1 0.2 2.9 0.3 0.0 0.0 1.5 1.7 3.0 3.8 4.3 0.0 0.0 0.0 0.2 1.4 0.2 0.0 1.0 3.1 0.8 17.3 29.0 0.0 2.7 2.0 0.4 0.3 17.0 1.1 0.7 0.0 19.3 61.1 0.2 2.2 0.0 7.4 0.7 0.0 4.7 4.2 3.4 1.2 2.4 16.0 4.7 0.2 0.9 0.0 10.1 1.4 0.1 0.1 1.9 0.2 0.3 0.1 0.1 0.0 0.5 0.0 7.4 4.9 4.9 0.6 0.5 1.7 0.3 1.2 4.6 1.1 0.1 DCPS "HINT-5, HINT5, HSL1, HSPC015" ENSG00000110063 "Decapping enzyme, scavenger" Q96C86 11 126304060-126350005 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 50.7" "Cell type enhanced" "Detected in many" "Plasma cells: 101.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 46.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 79.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039632, HPA058597" Supported Supported Nucleoplasm,Cytosol NA NA 1200000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Cytosol "HPA039632: AB_10794200, HPA058597: AB_2683770" "unprognostic (1.45e-1)" "unprognostic (5.48e-3)" "unprognostic (1.76e-1)" "unprognostic (3.55e-2)" "unprognostic (5.22e-2)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (2.90e-1)" "unprognostic (5.57e-2)" "unprognostic (1.91e-2)" "unprognostic (4.83e-2)" "unprognostic (5.00e-2)" "unprognostic (5.25e-2)" "unprognostic (2.24e-2)" "unprognostic (8.04e-2)" "unprognostic (7.67e-2)" "unprognostic (3.40e-2)" 8.3 11.4 2.8 7.4 4.0 12.1 8.5 5.0 4.5 10.9 8.1 10.1 4.7 11.0 4.1 11.3 8.6 16.0 9.9 3.9 3.2 13.5 50.7 9.0 12.1 3.3 3.4 9.2 12.1 3.5 8.2 4.0 2.9 8.1 5.9 6.3 12.0 5.3 14.6 11.3 9.4 5.5 2.7 17.3 8.7 6.1 3.6 8.9 7.5 5.8 9.6 13.3 9.2 3.4 13.9 8.5 10.2 19.8 7.9 11.2 8.9 6.5 10.3 11.5 10.8 17.5 29.1 19.5 28.0 12.2 7.5 16.2 14.4 24.4 5.9 35.8 7.1 27.1 9.9 14.7 18.8 33.3 25.4 12.5 14.0 16.0 17.6 5.9 14.1 17.0 11.6 34.8 11.2 21.6 21.1 41.5 8.0 79.8 28.7 13.7 13.8 40.6 11.4 15.1 16.1 11.0 20.3 21.1 15.8 6.3 33.8 22.1 9.3 18.7 7.3 8.9 13.7 13.4 14.6 20.0 6.0 51.0 46.7 4.2 10.5 4.3 9.3 15.2 7.8 13.0 8.5 9.7 16.6 8.6 6.4 6.7 1.3 8.9 15.3 46.6 15.4 8.9 2.8 4.0 5.0 4.5 3.9 3.2 3.3 3.4 2.9 2.7 3.6 3.4 14.2 12.8 11.2 6.2 31.2 6.9 16.4 38.7 8.0 6.7 12.2 17.1 5.0 47.1 18.8 42.3 0.0 39.9 35.3 6.4 56.7 19.7 8.1 11.1 12.1 12.4 7.3 14.5 5.8 29.2 43.8 15.9 11.2 23.2 17.1 9.8 8.6 31.4 29.2 3.3 6.0 12.0 28.5 14.1 11.7 2.2 17.1 16.8 17.8 2.8 15.3 10.1 22.6 2.5 4.6 17.1 14.9 18.4 101.1 8.7 6.1 15.0 15.7 9.4 19.7 10.8 14.6 14.8 24.9 18.3 8.9 27.1 24.3 16.2 14.4 24.0 DCX "DBCN, DC, LISX, SCLH, XLIS" ENSG00000077279 Doublecortin O43602 X 111293779-111412429 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;endometrium 1: 1.4;retina: 2.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 39.1;Inhibitory neurons: 90.2;Oligodendrocyte precursor cells: 49.8;Rod photoreceptor cells: 21.8" "Cancer enriched" "Detected in some" 5 "glioma: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SCLC-21H: 52.5;SH-SY5Y: 22.1" "Region enriched" "Detected in many" 9 "olfactory bulb: 74.0" "Region enriched" "Detected in all" 4 "olfactory bulb: 68.6" HPA036121 Enhanced Supported Approved Cytosol NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA036121: AB_2674950" "unprognostic (1.36e-2)" "unprognostic (1.99e-1)" "unprognostic (7.36e-2)" "unprognostic (4.00e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.00e-2)" "unprognostic (7.18e-2)" "unprognostic (3.24e-2)" "unprognostic (2.33e-3)" "unprognostic (3.67e-1)" "unprognostic (4.90e-4)" "unprognostic (5.02e-3)" "unprognostic (1.27e-1)" "unprognostic (1.85e-1)" 0.1 0.2 2.1 0.0 2.4 0.0 1.3 0.0 2.5 0.1 0.0 0.0 0.0 1.4 1.2 0.0 0.0 0.1 0.0 1.4 2.7 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.1 0.0 0.3 0.0 0.8 0.0 0.0 2.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 52.5 22.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.4 0.0 2.5 1.4 2.7 0.2 1.3 0.8 0.0 2.4 0.5 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.5 1.6 2.2 0.7 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 39.1 0.0 0.2 6.8 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 90.2 0.2 0.0 0.0 0.4 0.5 0.0 0.0 1.8 1.9 0.0 1.6 0.0 49.8 2.3 0.1 0.0 1.5 0.0 0.0 0.0 0.1 0.0 21.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 10.2 0.0 0.0 DDB1 ENSG00000167986 "Damage specific DNA binding protein 1" Q16531 11 61299451-61342596 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 352.3;Rod photoreceptor cells: 451.4;Syncytiotrophoblasts: 389.4;Theca cells: 303.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032821, HPA045174, HPA068456" Approved Enhanced Nucleoplasm NA NA 440000 "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB032821: AB_639050, HPA045174: AB_2679242, HPA068456: AB_2685992" "unprognostic (3.45e-1)" "unprognostic (8.38e-2)" "prognostic favorable (7.09e-4)" "unprognostic (1.21e-1)" "unprognostic (6.56e-2)" "unprognostic (1.19e-2)" "unprognostic (1.11e-2)" "unprognostic (9.33e-2)" "unprognostic (9.74e-3)" "unprognostic (1.09e-1)" "unprognostic (7.42e-3)" "unprognostic (3.11e-1)" "prognostic favorable (1.51e-8)" "unprognostic (3.44e-1)" "unprognostic (1.58e-1)" "unprognostic (7.30e-2)" "unprognostic (1.25e-3)" 52.8 164.8 30.2 44.0 32.5 47.2 59.0 29.5 30.2 61.3 42.5 50.0 53.2 48.0 79.7 49.7 78.3 39.9 65.1 31.9 36.4 64.8 55.9 43.1 47.0 31.8 33.5 89.3 42.5 232.1 44.5 129.7 36.9 56.6 52.3 162.5 54.1 70.9 133.1 60.6 49.9 61.9 31.9 41.9 44.4 69.1 33.5 81.2 65.0 125.1 66.6 58.6 39.2 36.1 160.3 168.1 159.0 142.2 151.4 139.2 237.8 140.9 193.6 174.4 129.2 188.7 130.7 237.6 126.8 203.4 107.4 141.4 245.5 177.5 188.0 115.7 131.3 128.0 144.3 192.0 109.4 182.7 112.6 169.1 121.7 174.0 146.2 123.5 195.7 86.0 278.4 119.9 158.9 194.7 238.4 77.4 214.5 104.3 146.3 197.9 198.5 254.3 119.7 177.3 140.3 143.0 154.6 183.8 145.9 144.8 226.0 85.6 150.9 120.9 113.6 138.2 106.4 139.5 157.0 194.7 134.9 103.7 121.1 38.4 43.6 36.5 46.7 47.1 61.1 35.8 42.0 47.3 60.5 30.5 37.8 43.3 4.6 46.4 45.3 34.2 49.6 54.6 30.2 32.5 29.5 30.2 31.9 36.4 31.8 33.5 36.9 31.9 33.5 36.1 34.2 28.9 69.9 46.4 48.8 52.6 53.6 61.1 51.2 87.0 52.0 39.9 105.6 34.3 54.5 53.3 352.3 283.5 57.5 45.0 17.6 43.9 15.7 46.6 40.8 48.1 74.2 102.3 27.8 42.4 130.1 50.6 46.4 51.3 30.9 102.7 45.0 67.4 75.5 87.5 31.6 55.4 44.7 45.3 33.5 18.8 85.1 38.3 42.7 30.0 61.1 64.4 71.1 24.1 31.0 52.6 36.4 62.1 65.4 55.7 63.2 46.7 64.4 451.4 32.9 51.5 44.5 114.0 120.9 52.3 59.8 389.4 46.0 303.8 60.0 57.1 DDB2 "DDBB, FLJ34321, UV-DDB2, XPE" ENSG00000134574 "Damage specific DNA binding protein 2" Q92466 11 47214465-47239217 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;monocytes: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025912, HPA058406" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cell Junctions" "CAB025912: , HPA058406: AB_2683708" "prognostic favorable (7.29e-4)" "prognostic favorable (1.58e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.20e-4)" "unprognostic (4.29e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-2)" "unprognostic (6.18e-2)" "unprognostic (2.25e-1)" "unprognostic (3.58e-3)" "unprognostic (3.53e-1)" "unprognostic (1.94e-1)" "unprognostic (4.57e-3)" "unprognostic (1.21e-2)" "unprognostic (4.25e-2)" "unprognostic (9.82e-3)" "unprognostic (1.07e-1)" 13.2 22.5 2.6 8.2 3.2 11.6 13.5 3.4 3.6 12.5 3.4 12.8 7.6 12.7 11.7 24.8 17.6 12.5 6.8 2.5 2.4 4.4 27.0 12.2 14.7 3.4 2.7 11.6 14.4 4.8 4.7 6.8 3.5 9.7 14.9 2.3 14.4 11.7 6.2 46.7 10.2 13.9 2.7 11.3 9.5 4.5 3.2 23.5 5.5 6.9 17.0 11.2 14.1 3.6 23.7 62.3 25.9 19.3 16.6 32.7 29.9 26.0 58.8 32.0 37.1 10.1 14.1 56.6 5.3 23.2 23.6 40.8 14.6 51.8 15.7 14.5 27.5 13.3 55.7 46.7 15.8 15.9 34.4 43.4 58.0 15.9 35.2 10.2 94.2 14.7 3.5 27.0 52.7 44.4 60.4 7.7 8.4 31.1 22.3 30.3 5.6 30.6 13.5 22.7 13.2 16.7 31.2 8.7 8.1 30.8 56.1 5.5 41.2 96.8 44.1 21.3 12.6 27.6 22.4 12.5 37.0 20.2 35.9 9.8 12.8 20.2 19.3 18.4 18.8 18.3 20.1 18.8 10.4 14.5 14.8 15.7 3.7 14.1 15.8 0.3 47.7 15.9 2.6 3.2 3.4 3.6 2.5 2.4 3.4 2.7 3.5 2.7 3.2 3.6 13.8 16.0 22.2 7.8 25.1 38.9 39.7 28.1 75.1 5.0 18.0 25.8 7.8 11.5 16.3 5.5 10.4 3.6 21.3 11.1 9.8 12.5 1.5 5.2 8.1 19.5 7.7 19.1 6.6 13.8 9.0 16.0 18.3 9.5 22.8 31.2 15.0 16.6 17.5 1.7 1.4 12.6 16.2 17.5 12.8 2.1 19.0 16.8 19.6 24.4 135.5 9.6 35.0 1.0 10.6 19.9 9.8 10.5 34.1 8.9 15.7 7.7 13.9 12.8 0.0 12.1 14.0 3.1 8.6 34.5 30.3 1.5 34.3 25.4 16.5 26.5 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 59.8 64.3 13.2 15.8 11.3 0.3 25.2 10.4 9.2 33.7 51.5 54.7 5.8 26.2 13.2 18.1 22.4 23.8 24.1 12.6 24.5 6.4 5.4 14.5 9.1 37.0 22.1 37.4 3.7 2.5 5.4 10.6 31.7 17.3 14.1 5.1 9.8 29.2 4.9 9.7 17.6 42.8 17.8 5.8 20.4 3.9 21.0 3.3 12.9 19.3 6.9 23.2 23.6 25.2 0.3 0.0 0.2 63.2 233.3 214.4 1.0 92.2 163.4 41.5 56.8 0.0 0.2 0.0 0.1 137.6 8.9 0.1 0.3 0.4 54.0 42.9 0.3 0.0 0.4 0.1 103.9 0.2 0.2 157.0 0.4 73.1 2.2 65.8 46.0 0.4 0.6 16.8 36.9 0.1 0.0 0.3 0.4 0.1 0.3 0.1 24.1 0.7 0.2 0.2 0.3 35.4 0.2 0.1 2.9 3.6 0.2 0.3 2.1 58.5 13.8 29.1 12.6 2.6 4.0 0.1 56.3 0.1 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 11.3 10.4 9.2 12.6 24.5 37.0 22.1 31.7 17.8 21.0 25.2 23.4 3.2 2.3 53.2 2.5 12.6 3.9 0.8 1.2 3.0 6.0 15.6 31.3 1.5 1.1 0.0 0.0 0.5 1.7 3.2 0.0 0.4 8.9 5.0 89.8 22.3 1.2 0.0 13.1 1.8 0.5 116.5 2.6 8.2 1.3 16.7 30.0 3.5 1.2 0.0 26.2 1.0 0.0 1.9 19.3 7.1 63.0 3.1 23.2 29.0 0.0 16.5 2.1 6.0 5.6 1.8 4.4 88.4 5.6 5.9 1.2 2.1 2.4 3.0 39.5 98.2 78.3 1.0 0.9 2.0 8.7 1.0 2.5 34.2 0.8 4.2 DDRGK1 "C20orf116, dJ1187M17.3, UFBP1" ENSG00000198171 "DDRGK domain containing 1" Q96HY6 20 3190350-3204685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013373, HPA013705" Approved Supported "Nucleoli,Endoplasmic reticulum" NA NA 24000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" Nucleoli "HPA013373: AB_2091955, HPA013705: AB_2668872" "unprognostic (2.99e-1)" "unprognostic (1.55e-1)" "unprognostic (3.42e-2)" "unprognostic (1.60e-1)" "unprognostic (6.54e-3)" "unprognostic (2.14e-1)" "unprognostic (1.19e-2)" "unprognostic (1.63e-1)" "unprognostic (4.10e-3)" "unprognostic (8.16e-2)" "unprognostic (5.44e-3)" "unprognostic (7.29e-2)" "prognostic favorable (2.01e-5)" "unprognostic (6.80e-3)" "unprognostic (1.43e-2)" "unprognostic (2.48e-2)" "unprognostic (6.90e-2)" 44.6 89.1 43.2 23.8 44.6 24.8 45.5 38.9 65.7 50.8 36.7 43.3 43.4 43.5 20.0 46.0 49.0 22.4 38.4 42.3 36.8 51.2 77.9 51.6 23.6 39.7 38.8 48.9 84.1 54.7 36.6 25.9 39.5 45.7 19.2 43.2 61.7 32.2 58.2 53.0 44.9 19.9 33.5 36.3 63.0 34.8 37.5 18.6 51.3 14.1 17.0 43.5 44.6 48.4 108.5 133.3 32.3 60.6 71.7 27.2 46.6 67.2 31.9 40.6 44.1 105.7 76.7 64.3 53.6 37.5 77.9 118.2 33.5 100.6 14.8 44.0 62.8 54.4 45.6 186.1 97.9 62.1 56.6 42.8 96.2 77.8 55.2 44.8 37.5 45.3 77.0 74.8 26.4 59.2 42.9 115.5 40.1 73.6 60.8 55.9 28.7 98.6 66.7 99.8 71.4 44.1 69.2 192.7 65.6 19.2 82.0 37.6 57.2 64.9 28.8 46.3 104.2 55.8 67.7 27.3 18.0 51.6 38.9 23.1 36.9 45.6 33.3 25.3 32.7 26.9 35.0 35.6 36.8 26.3 30.8 30.5 9.5 24.6 23.2 57.3 36.2 25.9 43.2 44.6 38.9 65.7 42.3 36.8 39.7 38.8 39.5 33.5 37.5 48.4 57.3 44.8 53.9 19.9 35.1 26.3 68.8 119.0 44.3 47.9 77.1 72.3 31.3 91.5 114.3 69.9 64.6 127.5 50.9 105.8 19.6 147.0 42.2 54.8 42.6 54.1 53.4 26.5 28.6 178.8 65.1 49.3 54.0 79.0 27.3 34.8 50.0 125.6 119.3 52.2 13.9 72.2 154.6 60.9 36.0 21.1 55.9 54.2 39.2 7.5 67.8 73.7 64.9 6.0 28.4 145.0 125.3 68.8 60.5 75.7 216.3 80.5 81.6 108.3 65.7 39.1 115.6 38.7 23.6 64.0 38.8 146.0 44.7 70.0 92.7 75.0 DDX11 "CHL1, CHLR1, KRG2, WABS" ENSG00000013573 "DEAD/H-box helicase 11" Q96FC9 12 31073860-31104799 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA065197 Supported Supported Nucleoplasm,Nucleoli No Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA065197: AB_2685430" "unprognostic (6.10e-2)" "unprognostic (1.48e-2)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (1.45e-1)" "unprognostic (2.79e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (4.87e-2)" "unprognostic (3.89e-3)" "unprognostic (3.53e-1)" "unprognostic (5.66e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.23e-8)" "unprognostic (1.89e-2)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (8.03e-3)" 5.9 6.4 6.0 10.2 6.8 29.2 7.2 6.9 7.3 10.7 7.1 9.6 8.0 7.5 4.3 9.5 8.0 5.9 5.3 6.0 6.1 9.2 9.3 6.1 13.2 6.9 6.4 11.0 17.5 5.8 9.4 5.4 6.9 10.0 10.1 6.6 8.6 5.3 10.6 16.7 13.4 3.6 6.1 13.8 9.6 8.8 6.7 24.0 8.0 6.6 11.1 6.9 9.8 6.9 36.5 35.0 42.2 34.5 5.8 11.0 58.7 21.8 10.4 25.2 28.5 44.1 58.6 49.2 23.9 10.8 23.6 35.0 31.7 28.9 21.3 43.4 66.6 47.4 71.0 25.4 2.1 37.4 35.0 11.9 13.0 32.6 24.8 16.9 12.6 55.2 26.6 103.3 17.6 30.9 64.5 60.7 84.0 39.9 19.5 55.0 53.3 66.2 13.3 38.5 30.2 21.7 23.4 33.2 10.4 65.0 27.3 25.5 8.2 22.0 42.1 42.2 40.0 39.4 29.6 95.3 24.6 32.5 20.3 0.0 1.3 0.8 2.0 1.2 1.5 2.5 1.9 1.5 1.5 2.6 2.0 2.6 0.5 2.2 4.4 2.4 2.0 1.3 6.0 6.8 6.9 7.3 6.0 6.1 6.9 6.4 6.9 6.1 6.7 6.9 10.1 3.2 9.5 1.6 9.0 6.0 4.0 6.0 2.2 9.4 8.3 7.1 2.5 4.3 6.0 0.0 14.6 7.6 8.8 7.8 0.0 2.0 1.7 5.5 8.9 5.4 0.0 15.3 2.5 3.3 7.5 5.7 9.7 7.4 5.7 15.6 6.1 7.7 5.2 8.4 3.6 6.5 10.2 4.1 5.4 1.3 7.2 4.4 7.2 3.7 3.5 2.7 4.1 1.5 1.7 3.2 2.7 4.5 17.2 6.0 2.3 1.4 6.7 25.8 0.0 4.9 4.8 5.3 18.0 5.5 6.5 2.6 8.4 4.1 9.5 5.1 DDX58 "DKFZp434J1111, FLJ13599, RIG-1, RIG-I, RIG1" ENSG00000107201 "DExD/H-box helicase 58" O95786 9 32455302-32526208 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "BJ hTERT+ SV40 Large T+: 79.0;BJ hTERT+ SV40 Large T+ RasG12V: 76.0;GAMG: 22.8" "CAB012643, HPA047193, HPA073217" Approved Supported "Plasma membrane,Cytosol" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB012643: , HPA047193: AB_2679978, HPA073217: " "unprognostic (1.10e-1)" "unprognostic (4.65e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.45e-1)" "unprognostic (2.37e-1)" "unprognostic (8.15e-2)" "unprognostic (4.57e-2)" "unprognostic (2.82e-1)" "unprognostic (6.48e-3)" "unprognostic (1.00e-2)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.22e-2)" "unprognostic (3.68e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" 6.3 4.9 3.5 7.5 2.9 1.3 6.0 3.0 4.3 7.1 3.1 6.3 2.9 5.6 4.7 6.4 4.4 6.0 4.1 2.7 3.6 5.5 6.3 7.1 7.4 5.2 3.7 4.6 5.7 2.5 5.2 5.7 4.0 4.2 5.3 2.3 10.0 3.5 4.8 7.8 7.1 5.7 6.5 9.2 4.8 2.8 3.6 15.6 4.3 1.7 5.2 5.1 5.3 2.9 4.3 2.4 2.5 2.2 7.5 6.4 2.7 2.1 14.6 79.0 76.0 2.4 1.4 0.4 2.7 2.7 22.8 2.8 2.3 1.3 11.4 7.4 0.9 1.1 2.4 3.5 5.0 1.4 4.5 4.9 1.3 6.9 1.3 4.2 14.3 1.5 1.8 1.0 6.6 0.6 3.8 12.4 1.8 0.6 2.0 2.4 3.1 0.0 11.6 0.6 2.0 0.3 1.7 1.7 12.6 1.7 3.5 0.9 13.4 1.5 0.9 1.7 1.1 0.0 0.3 0.9 2.6 3.3 2.1 0.0 0.1 0.3 0.2 0.1 0.3 0.2 0.3 0.0 0.0 0.2 0.2 0.2 1.3 0.4 0.2 0.0 0.2 0.0 3.5 2.9 3.0 4.3 2.7 3.6 5.2 3.7 4.0 6.5 3.6 2.9 41.7 22.4 8.8 20.5 13.9 4.2 5.1 7.2 13.6 4.1 5.8 5.1 5.1 5.7 6.7 1.8 2.1 5.6 13.9 13.8 0.0 19.5 2.7 12.9 8.7 23.6 3.0 5.7 10.4 12.2 7.6 13.9 21.9 20.3 5.1 16.8 9.3 6.7 5.6 6.7 13.2 4.6 4.1 7.3 4.6 0.4 6.5 11.6 0.0 39.4 12.3 6.4 21.6 31.2 17.5 16.2 7.7 6.0 9.1 4.9 16.9 7.2 7.3 2.5 6.6 16.8 13.1 0.5 2.3 10.9 5.4 2.5 17.8 10.4 2.6 5.3 DDX59 "DKFZP564B1023, ZNHIT5" ENSG00000118197 "DEAD-box helicase 59" Q5T1V6 1 200623896-200669907 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047166 Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 50: Non-specific - Ribosome" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Actin filaments" "HPA047166: AB_2679966" "unprognostic (1.99e-1)" "unprognostic (1.60e-1)" "unprognostic (3.44e-2)" "unprognostic (4.87e-2)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" "unprognostic (4.83e-2)" "unprognostic (3.40e-3)" "unprognostic (2.43e-3)" "unprognostic (4.16e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (9.02e-4)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (6.66e-2)" "unprognostic (5.98e-2)" 15.4 16.1 13.5 14.2 15.4 33.1 26.5 17.1 18.8 16.2 15.6 14.2 10.2 17.6 20.0 13.5 15.5 12.2 13.3 14.0 14.7 16.4 17.8 14.5 17.0 16.0 15.0 17.6 18.8 15.0 11.3 18.7 17.3 15.2 15.0 17.4 14.4 13.2 32.8 26.2 14.3 14.1 16.3 22.4 12.1 11.0 15.1 22.0 16.2 20.1 16.9 15.0 14.7 17.8 17.5 20.1 22.6 19.0 10.1 17.4 49.9 19.1 17.4 20.5 16.5 6.3 20.2 17.9 9.5 15.7 16.4 16.2 13.0 19.4 14.5 56.8 13.3 13.6 26.4 18.6 20.2 19.5 24.0 18.8 29.1 15.4 41.7 16.7 15.9 24.8 17.4 25.9 20.1 20.0 12.0 29.0 23.8 10.5 16.3 10.1 15.5 34.7 21.9 19.8 13.8 35.7 30.8 31.7 35.6 28.8 27.3 27.3 14.4 17.1 9.5 16.8 20.0 19.5 27.2 23.5 16.3 12.2 30.0 33.3 12.4 24.7 15.1 11.1 12.4 14.9 12.5 13.8 10.6 14.8 12.7 11.8 22.9 16.4 22.0 11.8 19.8 10.2 13.5 15.4 17.1 18.8 14.0 14.7 16.0 15.0 17.3 16.3 15.1 17.8 22.5 19.2 20.1 8.8 19.9 16.2 13.1 16.1 24.5 4.3 10.0 13.2 18.4 7.2 10.6 7.3 2.1 22.2 14.6 9.8 15.6 8.8 2.4 14.6 13.3 16.7 1.2 10.5 4.5 8.2 28.0 14.9 6.6 12.8 20.8 7.1 14.3 7.3 13.0 6.7 6.1 11.0 14.2 12.0 13.0 1.1 8.1 16.1 5.4 8.4 18.5 8.3 25.7 19.1 10.3 8.8 7.9 13.5 13.1 12.0 8.0 11.6 10.8 6.7 0.0 22.8 15.7 14.2 20.0 12.9 15.6 43.8 18.9 9.3 8.5 11.1 DHCR24 "DCE, KIAA0018, seladin-1" ENSG00000116133 "24-dehydrocholesterol reductase" Q15392 1 54849627-54887195 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1129.5;liver: 623.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 298.1;Alveolar cells type 2: 682.3;Hepatocytes: 1091.4;Theca cells: 442.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1031.9" "Low region specificity" "Detected in all" "HPA017981, CAB037247, HPA063005" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB037247: AB_796187, HPA017981: AB_2732422, HPA063005: AB_2684919" "unprognostic (2.88e-1)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "prognostic unfavorable (1.05e-5)" "unprognostic (1.69e-1)" "unprognostic (2.61e-1)" "unprognostic (1.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.68e-1)" "unprognostic (1.86e-1)" "unprognostic (6.18e-3)" "unprognostic (3.35e-1)" "unprognostic (7.82e-3)" "unprognostic (5.48e-2)" "unprognostic (1.83e-1)" "unprognostic (1.70e-1)" "unprognostic (3.97e-2)" 58.3 1129.5 35.7 19.8 58.5 1.6 104.8 125.3 73.0 54.9 30.4 55.6 62.2 13.1 1.6 296.1 60.4 42.2 18.0 55.9 63.9 48.6 623.5 215.9 9.4 216.2 91.3 28.5 30.5 157.9 17.0 21.6 158.9 128.6 40.5 15.8 136.2 8.3 197.7 247.6 29.6 12.6 129.3 134.1 98.9 74.2 87.9 10.1 15.4 11.1 33.9 13.5 103.9 280.7 342.1 58.5 210.6 257.1 1031.9 219.0 50.5 94.8 160.3 130.7 268.6 341.6 210.2 55.3 191.5 82.4 427.4 319.2 250.5 501.3 118.3 8.3 159.6 303.3 131.8 421.7 168.9 126.7 68.2 161.0 429.0 397.6 74.7 66.7 67.2 124.5 224.7 0.2 50.2 143.5 25.8 111.4 592.0 90.7 164.2 0.3 54.2 166.3 735.3 257.1 144.5 53.2 185.0 337.5 123.1 221.6 441.5 143.3 62.2 45.3 130.0 66.1 183.9 22.7 55.0 91.2 32.8 215.3 60.4 5.1 1.5 0.7 6.0 1.8 0.3 3.7 2.5 2.6 5.2 1.3 2.2 2.9 0.0 2.7 0.7 3.0 0.4 4.4 35.7 58.5 125.3 73.0 55.9 63.9 216.2 91.3 158.9 129.3 87.9 280.7 6.2 298.1 682.3 12.4 13.3 31.5 17.3 150.6 79.1 9.7 87.9 33.1 15.3 145.8 205.2 68.0 0.0 35.2 6.4 133.3 3.9 55.3 22.9 14.5 5.8 13.5 24.0 71.6 14.5 76.5 34.4 17.5 38.7 44.7 32.2 26.4 111.0 1091.4 28.0 5.0 8.7 39.2 69.2 68.9 8.2 77.2 14.0 9.4 14.2 1.9 6.8 3.6 2.1 5.5 62.6 48.6 27.7 7.9 1.8 52.4 22.6 14.4 136.3 6.4 0.0 1.5 23.2 5.4 14.7 145.4 80.4 30.6 10.6 442.4 35.2 45.2 DHODH ENSG00000102967 "Dihydroorotate dehydrogenase (quinone)" Q02127 16 72008588-72027664 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Pyrimidine biosynthesis" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 105.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 124.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010123, HPA011942" Approved Enhanced Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "Nucleoplasm, Cytosol" "HPA010123: AB_1847648, HPA011942: AB_1847649" "unprognostic (4.88e-2)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-2)" "unprognostic (1.41e-3)" "unprognostic (2.10e-1)" "unprognostic (4.27e-2)" "unprognostic (1.31e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-1)" "unprognostic (2.14e-1)" "unprognostic (6.40e-2)" "unprognostic (9.26e-3)" "unprognostic (1.98e-1)" "unprognostic (1.97e-1)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" 7.4 4.8 3.1 4.2 3.6 3.9 5.8 3.7 3.7 4.0 3.7 5.4 3.9 5.4 2.8 4.2 6.1 2.3 13.8 2.9 2.5 8.0 105.9 3.9 4.2 3.4 3.3 4.9 4.2 6.2 2.5 2.7 3.3 4.0 5.8 3.2 5.4 4.5 10.0 4.5 3.1 5.7 2.1 4.1 4.1 3.6 3.4 3.9 4.1 8.1 5.5 3.9 3.4 5.2 12.5 25.7 6.9 12.1 3.8 5.0 13.9 10.5 4.2 15.6 11.6 20.4 11.1 27.8 13.6 5.7 8.6 12.5 13.7 11.4 18.2 6.0 13.3 15.4 12.6 20.3 10.6 21.4 10.8 4.9 11.3 18.6 19.7 4.7 11.3 18.3 23.9 4.4 9.7 32.7 20.2 17.0 15.9 21.1 10.0 24.9 9.6 29.4 9.4 7.8 8.5 10.2 14.1 14.8 6.8 8.7 13.0 10.3 5.1 14.1 8.3 13.1 15.2 8.8 18.7 46.3 7.1 22.4 12.8 6.1 8.4 1.0 9.4 8.8 12.9 12.0 8.5 9.3 14.5 11.7 11.7 12.6 2.1 10.1 6.3 13.5 8.0 7.2 3.1 3.6 3.7 3.7 2.9 2.5 3.4 3.3 3.3 2.1 3.4 5.2 6.3 3.2 13.1 1.6 7.1 5.6 7.8 11.2 6.8 5.6 6.6 7.1 14.8 15.7 5.5 7.3 4.2 12.3 6.9 1.6 5.9 10.3 2.9 3.8 6.3 9.1 1.2 7.8 2.0 5.1 12.4 7.4 2.6 3.2 8.2 10.2 5.3 124.1 7.9 3.3 2.3 6.6 10.2 6.0 3.1 3.6 2.8 3.3 12.4 1.0 3.8 5.2 8.2 4.0 4.4 5.9 2.4 2.2 4.6 11.2 1.0 20.8 8.1 5.2 0.0 9.7 9.1 6.8 8.1 5.0 3.8 2.9 4.3 13.5 6.7 4.2 DHX37 "DDX37, Dhr1, KIAA1517, MGC2695, MGC4322" ENSG00000150990 "DEAH-box helicase 37" Q8IY37 12 124946825-124989131 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047607 Approved Approved "Nuclear membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear membrane" "HPA047607: AB_2680101" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.32e-1)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (9.54e-10)" "unprognostic (2.38e-2)" "unprognostic (5.14e-2)" "unprognostic (2.90e-2)" "unprognostic (2.07e-1)" "unprognostic (3.16e-2)" "unprognostic (8.28e-3)" "unprognostic (1.40e-2)" "unprognostic (2.27e-1)" "unprognostic (2.85e-2)" "unprognostic (2.73e-1)" 4.3 3.2 2.9 6.8 3.4 8.8 3.6 3.0 3.6 3.5 1.4 3.4 4.4 3.8 1.3 4.7 3.4 2.8 3.6 2.9 2.5 3.3 3.0 2.8 7.4 4.1 3.6 4.5 6.6 2.6 1.6 2.9 3.4 3.3 1.6 0.5 4.3 2.6 10.8 4.0 3.8 2.5 3.0 5.2 3.9 2.6 3.2 4.6 3.2 4.9 3.9 5.0 3.6 4.3 17.3 45.5 5.2 21.9 6.7 6.6 27.4 13.8 7.3 19.5 11.6 44.7 9.4 37.5 24.6 11.4 19.7 21.9 19.8 15.6 4.5 32.7 38.2 23.0 13.8 23.7 13.4 27.7 30.5 8.8 10.8 24.3 4.0 7.2 10.0 17.4 44.4 7.5 7.5 23.9 29.5 28.5 39.2 15.1 36.4 31.4 11.0 21.5 8.6 22.6 17.6 11.1 14.0 16.3 16.0 5.1 19.3 19.5 13.1 16.1 20.2 20.0 27.6 31.6 33.2 44.0 15.1 22.2 27.2 0.0 1.5 0.0 1.6 1.7 1.4 1.8 1.3 1.6 1.4 1.4 0.9 1.4 0.0 0.9 0.8 1.1 0.7 1.4 2.9 3.4 3.0 3.6 2.9 2.5 4.1 3.6 3.4 3.0 3.2 4.3 5.5 3.2 5.2 3.3 10.3 4.2 3.4 2.8 4.0 3.5 6.2 5.3 3.8 2.8 4.1 0.0 0.0 4.1 6.7 8.8 3.9 4.8 1.7 5.3 9.6 5.7 9.0 5.0 3.0 6.2 6.0 4.8 8.2 7.8 6.3 9.3 2.2 6.2 5.4 13.5 2.0 7.1 6.1 7.2 2.5 2.0 5.3 4.9 0.0 1.9 6.6 2.2 6.2 3.0 4.0 9.0 2.2 2.6 9.2 4.9 2.8 4.7 4.1 2.1 6.6 7.1 3.8 1.5 5.6 8.0 4.0 2.9 7.7 5.9 9.3 4.0 DIS3L2 "FAM6A, FLJ36974, MGC42174" ENSG00000144535 "DIS3 like 3'-5' exoribonuclease 2" Q8IYB7 2 231961245-232344350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 93.4;Oligodendrocytes: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035796, HPA035797" Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA035796: AB_2674786, HPA035797: AB_10669978" "unprognostic (1.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.05e-2)" "unprognostic (2.40e-2)" "unprognostic (8.17e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (3.41e-4)" "unprognostic (2.21e-1)" "unprognostic (6.45e-2)" "unprognostic (3.26e-2)" "unprognostic (1.64e-1)" "unprognostic (1.63e-1)" "unprognostic (5.93e-2)" "unprognostic (2.16e-1)" "unprognostic (3.55e-3)" "unprognostic (3.02e-1)" "unprognostic (1.97e-1)" 8.9 10.2 10.7 7.8 11.1 10.5 10.7 14.2 12.8 13.9 13.2 10.4 7.0 11.3 9.2 16.3 12.7 7.7 10.1 10.6 11.1 12.3 10.7 9.6 10.5 11.8 10.7 14.6 11.3 12.3 12.1 9.2 11.1 13.1 8.5 15.3 10.4 9.0 9.1 15.7 9.4 8.9 9.1 11.3 10.6 14.1 11.9 14.6 15.1 7.3 9.6 11.3 12.3 15.2 12.6 13.1 19.8 11.8 11.1 11.4 18.8 11.5 11.6 12.8 11.8 10.9 17.1 10.5 9.5 12.3 17.0 15.3 11.7 15.2 13.3 16.9 12.9 16.2 15.7 22.4 10.3 14.7 15.7 9.0 16.7 11.1 11.7 13.3 16.6 17.0 17.6 7.2 11.1 16.9 20.4 27.8 13.6 12.0 6.9 17.1 24.4 9.6 16.0 21.4 15.9 23.2 10.1 20.6 14.3 13.3 11.3 18.3 16.3 16.5 17.0 14.5 12.9 19.3 10.0 11.8 12.5 10.6 15.8 0.1 3.7 3.0 4.8 4.3 5.1 4.8 4.3 4.4 3.8 9.2 4.5 5.1 0.4 4.0 3.4 5.7 5.1 2.3 10.7 11.1 14.2 12.8 10.6 11.1 11.8 10.7 11.1 9.1 11.9 15.2 12.9 3.2 9.1 64.6 19.5 9.9 17.8 11.4 19.9 33.7 7.9 7.4 9.3 11.5 17.4 12.9 66.7 14.2 9.0 13.0 3.9 15.1 82.3 23.7 15.7 12.1 8.4 12.0 82.6 10.6 14.2 10.1 12.2 13.7 1.3 22.8 10.0 7.4 8.6 40.4 93.4 10.9 12.2 12.8 8.7 30.7 10.5 9.7 5.4 42.2 10.6 15.4 20.6 57.8 150.8 15.0 10.2 10.5 11.1 10.0 11.0 10.9 19.0 56.0 19.7 22.2 11.6 20.6 13.0 15.0 9.7 9.9 17.0 15.5 13.8 15.6 DLL1 ENSG00000198719 "Delta like canonical Notch ligand 1" O00548 6 170282206-170306565 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 53.9" "Cell type enhanced" "Detected in many" "Adipocytes: 88.8;Basal keratinocytes: 66.9;Basal squamous epithelial cells: 82.0;Enteroendocrine cells: 51.9;Intestinal goblet cells: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 3.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 3.3" "Cell line enhanced" "Detected in some" "HaCaT: 6.8;HBEC3-KT: 4.5;NB-4: 14.2;THP-1: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001255 Approved "Plasma membrane" NA NA 690000 "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "HPA001255: " "unprognostic (1.03e-1)" "unprognostic (9.22e-2)" "unprognostic (2.17e-3)" "unprognostic (1.95e-1)" "unprognostic (2.89e-2)" "unprognostic (6.35e-2)" "unprognostic (1.63e-2)" "unprognostic (1.89e-1)" "unprognostic (9.22e-2)" "unprognostic (1.14e-2)" "unprognostic (1.39e-2)" "unprognostic (2.64e-2)" "unprognostic (5.23e-3)" "unprognostic (3.50e-1)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.66e-1)" 20.9 8.6 2.8 2.1 6.9 0.7 19.2 3.3 4.5 21.1 0.2 15.4 3.9 10.1 0.3 21.9 11.5 0.8 15.9 2.2 2.9 12.5 6.4 13.1 1.9 6.0 5.1 4.2 16.9 0.3 6.2 1.2 4.8 28.7 0.9 0.4 17.7 1.1 5.3 26.2 19.3 0.8 2.0 53.9 10.9 1.6 4.0 0.2 12.4 0.7 0.4 9.6 22.9 11.0 0.7 0.1 3.3 2.0 0.1 0.1 1.5 0.3 0.2 0.2 0.3 1.0 0.1 0.0 0.3 0.1 0.6 6.8 1.4 4.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.6 0.0 0.4 0.1 0.7 0.0 0.0 0.0 0.1 0.8 0.0 14.2 0.2 0.1 0.0 1.1 2.8 0.0 0.0 0.4 1.6 0.2 0.1 0.0 0.0 1.1 0.4 14.8 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.4 0.0 0.0 0.1 2.8 6.9 3.3 4.5 2.2 2.9 6.0 5.1 4.8 2.0 4.0 11.0 88.8 0.0 0.5 26.1 2.7 66.9 14.9 31.2 82.0 1.4 5.4 14.7 11.8 0.0 7.2 1.8 22.9 3.1 3.0 3.0 0.0 0.3 0.4 5.1 10.1 28.5 51.9 0.4 6.9 1.8 5.9 19.2 1.5 5.3 5.7 0.2 21.4 0.2 1.3 0.0 6.4 80.3 16.2 4.8 6.6 1.9 0.3 2.7 7.2 4.7 0.2 1.1 0.0 28.6 26.7 0.7 2.5 1.2 0.3 4.8 2.5 0.1 9.0 0.6 13.1 12.3 8.2 0.5 2.0 8.5 12.8 3.7 4.7 0.1 3.6 1.1 DLL3 SCDO1 ENSG00000090932 "Delta like canonical Notch ligand 3" Q9NYJ7 19 39498895-39508481 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 5.7;choroid plexus: 2.3;pituitary gland: 3.4;testis: 1.4" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 24.6;Spermatogonia: 39.5" "Group enriched" "Detected in many" 11 "glioma: 29.2;melanoma: 15.5;testis cancer: 8.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.6;naive CD8 T-cell: 1.4" "Group enriched" "Detected in many" 13 "B-cells: 2.6;T-cells: 1.4" "Cell line enriched" "Detected in some" 6 "SK-MEL-30: 83.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024559, HPA056533" Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Golgi apparatus, Plasma membrane" "HPA024559: , HPA056533: " "unprognostic (2.52e-1)" "unprognostic (3.81e-1)" "unprognostic (3.13e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.85e-2)" "unprognostic (1.41e-2)" "unprognostic (1.65e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (6.58e-2)" "unprognostic (1.06e-2)" "unprognostic (4.20e-2)" "unprognostic (3.82e-4)" "unprognostic (4.94e-2)" "unprognostic (5.13e-2)" "unprognostic (4.15e-2)" "unprognostic (2.97e-1)" 0.0 0.0 5.1 0.1 5.7 0.0 0.0 3.1 5.6 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 4.7 0.0 0.0 0.0 0.1 4.9 4.7 0.2 0.0 0.5 3.4 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.1 0.0 1.4 4.6 0.0 0.1 0.0 0.1 0.0 0.0 5.4 0.1 3.9 0.9 2.0 0.0 0.0 0.6 1.1 0.0 0.7 0.2 0.5 0.9 0.1 3.7 0.0 1.5 0.1 2.3 1.0 0.2 1.2 6.0 0.2 0.1 0.3 0.3 1.0 4.6 0.0 0.0 0.1 0.1 0.1 0.1 4.3 1.1 0.1 0.3 0.0 0.2 0.0 0.7 0.0 6.2 0.6 0.2 0.2 0.2 0.2 13.6 14.1 2.9 0.1 83.7 0.3 0.0 0.2 0.0 0.0 2.6 0.1 1.0 1.4 0.0 0.9 0.1 0.5 2.3 0.0 0.0 0.0 0.3 0.0 0.1 2.6 0.1 0.5 0.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 5.1 5.7 3.1 5.6 4.7 4.7 4.9 4.7 4.2 4.4 4.6 5.4 0.3 0.0 0.0 0.3 1.1 0.3 0.3 0.4 0.0 0.5 1.3 4.7 0.5 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.7 0.6 0.1 0.7 0.2 3.0 0.0 1.7 0.6 0.6 1.0 0.5 0.3 0.0 1.7 0.0 0.0 0.3 0.0 3.4 0.3 0.0 0.0 0.0 2.2 1.2 0.1 1.8 0.0 0.0 0.9 0.0 24.6 0.5 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.7 6.6 0.0 0.6 6.5 39.5 0.2 0.1 0.3 0.5 1.7 0.0 0.1 DLL4 ENSG00000128917 "Delta like canonical Notch ligand 4" Q9NR61 15 40929340-40939073 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Angiogenesis, Differentiation, Neurogenesis, Notch signaling pathway, Sensory transduction, Vision" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 70.7;Distal enterocytes: 24.2;Endothelial cells: 48.6;Hepatic stellate cells: 30.4;Intestinal goblet cells: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "BJ hTERT+: 59.4;HUVEC TERT2: 15.7;SCLC-21H: 32.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023392 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023392: AB_1847740" "unprognostic (1.92e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (7.52e-2)" "unprognostic (4.71e-2)" "unprognostic (2.72e-1)" "unprognostic (4.16e-2)" "unprognostic (3.56e-2)" "unprognostic (1.60e-2)" "unprognostic (2.49e-1)" "unprognostic (2.73e-1)" "unprognostic (3.51e-2)" "unprognostic (6.10e-2)" "unprognostic (2.56e-3)" "unprognostic (9.92e-2)" "unprognostic (2.93e-1)" "unprognostic (1.51e-2)" "unprognostic (5.51e-3)" 25.2 2.6 6.9 2.9 6.1 0.3 21.2 6.5 7.0 8.0 4.9 7.6 4.0 8.8 1.0 3.7 7.6 3.7 23.8 5.8 6.0 10.0 3.5 22.5 5.0 7.1 6.5 4.1 2.9 2.9 5.6 19.8 7.5 7.9 3.0 0.9 4.3 2.7 10.0 5.5 6.8 4.2 6.6 4.6 4.8 1.5 8.4 5.0 15.4 10.6 1.7 8.7 7.6 6.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.9 59.4 0.2 0.3 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.1 0.0 1.0 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 0.4 1.1 0.1 0.1 0.0 0.6 0.0 0.9 0.0 1.4 0.5 1.6 0.0 0.1 32.5 0.0 0.3 0.7 0.0 0.0 0.0 3.5 0.9 0.0 0.1 0.0 0.0 1.3 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 6.1 6.5 7.0 5.8 6.0 7.1 6.5 7.5 6.6 8.4 6.2 70.7 0.0 2.7 0.0 1.7 1.3 0.2 0.2 4.0 4.9 1.6 2.8 3.2 1.5 0.9 0.0 0.0 1.5 0.2 24.2 0.0 0.2 0.2 1.9 0.7 48.6 17.4 0.0 0.9 0.2 0.6 3.1 13.3 2.6 2.5 0.0 30.4 0.1 0.2 0.0 0.6 36.3 6.1 1.6 0.8 0.3 0.0 0.8 1.8 11.2 0.0 0.2 0.0 0.5 0.5 0.2 16.7 0.0 3.5 2.3 9.2 0.0 0.2 1.4 0.0 0.9 3.8 0.8 2.0 1.0 1.6 1.9 0.4 0.4 12.0 0.6 DLX3 ENSG00000064195 "Distal-less homeobox 3" O60479 17 49990005-49995224 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 53.8" "Group enriched" "Detected in some" 7 "Cytotrophoblasts: 35.9;Extravillous trophoblasts: 69.1;Syncytiotrophoblasts: 96.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 135.9;SK-BR-3: 44.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA031164 Approved Nucleoplasm,Cytosol NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA031164: AB_10603565" "unprognostic (1.20e-1)" "unprognostic (1.75e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (4.61e-4)" "unprognostic (1.95e-1)" "unprognostic (2.63e-2)" "unprognostic (1.02e-1)" "unprognostic (2.55e-1)" "unprognostic (1.77e-2)" "unprognostic (7.98e-2)" "unprognostic (1.44e-5)" "unprognostic (3.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.49e-1)" "unprognostic (2.20e-1)" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" 0.5 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.5 1.9 0.1 0.1 0.0 0.0 0.3 3.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.4 0.0 0.4 0.9 0.3 0.2 0.6 0.2 7.4 0.4 0.5 0.0 0.0 1.5 0.7 0.0 53.8 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.2 1.8 0.0 3.0 0.4 4.0 0.0 0.5 0.0 0.0 2.6 0.8 0.6 135.9 0.1 0.0 0.0 0.0 1.3 0.2 0.0 1.5 1.6 0.0 17.1 7.1 0.1 0.0 0.0 0.3 0.0 4.2 0.2 0.0 0.0 0.5 0.0 12.7 0.4 0.0 0.0 0.0 0.9 0.1 0.0 1.7 4.1 0.0 0.4 0.5 0.3 0.6 0.0 0.0 0.3 0.0 1.9 15.1 0.1 1.5 44.1 0.0 9.1 17.5 0.9 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.1 0.4 0.9 0.4 0.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 5.0 0.4 1.1 9.1 0.0 3.5 5.3 2.0 0.0 0.2 0.0 0.0 35.9 0.0 0.0 0.0 0.6 0.0 0.2 0.2 0.3 0.0 0.0 0.2 0.0 69.1 0.7 0.0 0.2 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.1 1.0 0.0 2.0 3.4 5.1 96.0 0.1 0.0 0.0 0.5 DLX4 "BP1, DLX7, DLX8, DLX9" ENSG00000108813 "Distal-less homeobox 4" Q92988 17 49968970-49974959 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 3.7;skin 1: 3.0" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 77.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 22.9;CACO-2: 16.8;GAMG: 15.3;HAP1: 11.2;K-562: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA059933 Uncertain Supported Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA059933: AB_2684169" "unprognostic (8.12e-2)" "unprognostic (2.48e-1)" "unprognostic (1.26e-2)" "unprognostic (2.29e-3)" "unprognostic (7.49e-2)" "unprognostic (2.71e-1)" "unprognostic (9.35e-3)" "unprognostic (2.85e-2)" "unprognostic (8.73e-2)" "unprognostic (5.93e-2)" "unprognostic (1.29e-2)" "unprognostic (4.34e-2)" "unprognostic (2.88e-13)" "unprognostic (8.79e-3)" "unprognostic (2.77e-1)" "unprognostic (5.00e-2)" "unprognostic (6.86e-2)" 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.1 0.6 0.3 0.1 0.2 0.1 0.0 0.2 0.7 0.2 0.0 0.1 0.2 0.1 0.2 0.0 0.6 0.2 0.2 0.8 0.0 0.3 0.2 0.1 3.7 0.5 0.2 0.1 0.0 1.1 0.2 0.0 3.0 0.2 0.0 0.2 0.4 0.1 0.3 0.2 0.1 0.3 0.0 0.5 0.2 0.5 0.2 0.5 1.4 0.0 0.1 0.1 0.0 22.9 0.1 0.1 0.1 0.3 16.8 1.0 0.7 3.3 0.3 15.3 2.3 11.2 0.4 0.1 4.5 5.9 0.4 5.7 1.7 0.0 0.9 3.7 0.0 2.8 0.1 0.0 0.2 0.0 3.5 13.5 0.0 0.0 2.9 0.4 6.0 0.2 3.1 0.0 0.0 5.1 0.6 0.1 0.8 1.9 0.1 0.4 1.9 1.1 3.4 4.1 4.0 0.0 0.0 1.0 0.2 0.0 0.9 0.2 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.2 0.1 0.6 0.2 0.1 0.2 0.8 0.5 0.2 0.2 0.2 0.0 6.4 0.0 0.0 0.2 2.5 0.4 1.0 2.2 0.0 0.5 0.3 1.9 0.0 0.1 0.0 0.0 12.7 0.1 0.1 0.0 0.3 0.1 1.5 0.1 0.2 0.0 0.0 0.3 0.2 77.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 1.0 1.1 0.4 0.6 16.8 0.1 0.2 0.2 0.3 DLX5 ENSG00000105880 "Distal-less homeobox 5" P56178 7 97020396-97024950 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Osteogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 14.1;placenta: 11.7;skin 1: 21.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 168.9;Endometrial ciliated cells: 217.8;Extravillous trophoblasts: 245.2;Glandular and luminal cells: 191.2;Syncytiotrophoblasts: 314.8" "Cancer enriched" "Detected in many" 11 "endometrial cancer: 81.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 53.7;HAP1: 27.2;SuSa: 13.4" "Group enriched" "Detected in many" 4 "basal ganglia: 13.5;olfactory bulb: 29.8" "Group enriched" "Detected in many" 4 "basal ganglia: 7.5;olfactory bulb: 18.0" HPA005670 Approved Approved Nucleoplasm NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA005670: AB_1078681" "unprognostic (3.99e-1)" "unprognostic (1.05e-1)" "unprognostic (2.96e-2)" "unprognostic (1.31e-3)" "unprognostic (1.76e-1)" "unprognostic (2.86e-2)" "unprognostic (6.14e-2)" "unprognostic (2.46e-2)" "unprognostic (5.89e-2)" "unprognostic (6.20e-2)" "unprognostic (1.52e-1)" "unprognostic (1.01e-2)" "unprognostic (7.43e-8)" "unprognostic (1.39e-2)" "unprognostic (3.73e-1)" "unprognostic (1.16e-1)" "unprognostic (2.55e-1)" 1.5 0.3 2.1 0.2 3.9 0.0 0.9 0.2 3.4 7.6 0.4 0.6 0.3 14.1 1.0 1.9 1.3 0.4 0.5 1.5 4.5 0.5 0.0 0.2 1.7 0.2 0.3 1.6 0.0 0.2 0.8 11.7 0.3 1.7 0.0 0.0 3.3 2.8 0.3 21.2 0.1 0.9 0.3 0.1 0.1 0.9 1.5 1.8 1.5 0.0 2.1 0.7 3.0 1.3 0.0 0.0 0.0 8.2 0.0 0.0 53.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 6.2 27.2 0.0 0.0 0.0 4.6 0.0 0.6 0.4 0.0 0.0 0.0 0.1 8.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.0 3.6 1.5 2.1 0.2 0.0 0.0 13.4 0.0 0.0 0.0 1.7 0.3 0.4 0.0 0.0 0.0 0.0 3.2 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 3.9 0.2 3.4 1.5 4.5 0.2 0.3 0.3 0.3 1.5 1.3 1.4 0.0 0.0 0.0 0.0 9.8 1.1 1.7 0.6 0.0 0.3 0.6 0.2 0.0 0.1 0.0 0.0 168.9 0.0 0.0 0.0 0.0 0.2 217.8 13.3 2.9 0.0 0.0 0.1 0.0 245.2 1.5 0.0 191.2 0.0 1.6 0.0 0.0 16.9 0.0 12.8 0.0 0.0 0.0 1.1 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.1 59.2 0.2 8.0 4.2 11.6 7.9 20.6 314.8 1.6 0.1 0.0 1.6 DNA2 "DNA2L, KIAA0083" ENSG00000138346 "DNA replication helicase/nuclease 2" P51530 10 68414064-68472121 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Disease variant, Dwarfism, Mental retardation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 33.2;Excitatory neurons: 14.1;Inhibitory neurons: 15.5;Oligodendrocytes: 18.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.8" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037487, HPA057526" Approved Supported Mitochondria No Yes "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA037487: AB_10672493, HPA057526: AB_2683456" "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-3)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (4.50e-5)" "unprognostic (3.36e-2)" "unprognostic (4.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.30e-2)" "unprognostic (3.29e-4)" "unprognostic (1.09e-10)" "unprognostic (3.43e-2)" "unprognostic (1.98e-1)" "unprognostic (9.36e-2)" "unprognostic (1.23e-2)" 1.3 0.9 1.9 2.8 2.1 4.6 1.8 2.5 3.6 1.4 1.0 2.3 2.1 1.1 0.9 1.9 0.9 0.9 1.8 1.8 1.9 2.6 4.2 1.8 5.2 2.3 1.9 1.2 1.6 0.4 1.5 1.6 2.4 1.9 2.8 5.3 1.6 0.4 1.6 1.8 3.2 1.1 1.6 2.1 1.9 2.9 2.1 8.1 1.0 0.9 4.2 1.4 1.4 3.2 25.6 13.0 29.0 20.7 3.2 2.2 20.4 12.4 10.3 17.4 21.2 31.1 16.1 26.1 4.6 3.8 6.7 15.2 16.8 6.5 20.7 16.2 12.6 15.8 8.5 12.3 0.9 27.7 16.4 1.8 2.6 12.3 3.6 4.5 7.9 17.0 23.6 22.8 10.1 9.0 42.8 19.8 20.5 10.9 24.0 33.1 20.0 8.4 7.5 11.7 13.1 15.7 16.9 21.4 4.2 20.1 16.5 11.6 3.4 6.6 20.5 8.5 23.8 11.5 13.9 38.3 5.7 26.1 8.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.1 0.0 1.8 0.0 0.0 0.1 0.0 1.9 2.1 2.5 3.6 1.8 1.9 2.3 1.9 2.4 1.6 2.1 3.2 1.0 6.4 1.1 4.9 1.3 2.3 0.9 1.7 2.8 2.5 2.3 1.4 10.5 2.8 1.1 1.8 6.2 3.9 2.2 1.7 0.0 0.8 2.2 2.0 1.4 2.0 1.2 33.2 14.1 0.9 4.8 2.0 2.6 2.8 0.0 6.0 0.7 4.6 2.2 0.0 15.5 1.8 0.0 1.3 0.7 3.7 0.6 1.5 0.0 4.7 0.5 0.5 2.1 5.5 18.4 0.7 0.1 0.7 7.4 2.5 2.4 0.6 0.8 4.3 0.0 2.4 1.1 9.1 12.2 4.7 1.7 1.2 1.6 0.7 3.7 1.0 DNAJB11 "EDJ, ERdj3, HEDJ" ENSG00000090520 "DnaJ heat shock protein family (Hsp40) member B11" Q9UBS4 3 186567403-186585800 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010814, HPA017051" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA010814: AB_1078691, HPA017051: AB_1847792" "unprognostic (4.29e-1)" "unprognostic (1.07e-1)" "unprognostic (2.98e-2)" "unprognostic (2.24e-2)" "unprognostic (8.53e-2)" "unprognostic (1.07e-3)" "unprognostic (3.86e-2)" "unprognostic (6.52e-2)" "unprognostic (7.95e-2)" "unprognostic (2.14e-3)" "unprognostic (2.58e-2)" "unprognostic (1.05e-3)" "prognostic unfavorable (3.44e-9)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.33e-1)" "unprognostic (1.82e-1)" 36.1 26.3 17.3 51.5 18.8 50.1 28.2 20.1 19.8 30.3 21.0 38.9 35.2 31.5 36.7 33.2 28.7 28.1 42.9 17.9 20.1 33.0 81.8 35.8 34.5 21.1 19.8 20.5 62.3 31.7 27.0 46.2 20.2 23.3 37.2 16.1 34.3 23.1 22.9 23.9 38.4 30.9 19.3 41.7 37.8 27.1 20.0 30.7 53.2 15.8 36.5 40.6 26.1 21.6 154.5 60.5 87.5 150.5 69.6 53.1 142.4 166.5 98.5 138.6 145.9 187.0 100.5 109.4 326.7 113.3 199.6 139.1 96.0 88.0 135.6 123.7 81.7 97.8 57.0 128.8 150.8 116.8 149.0 46.6 85.5 78.0 130.6 76.4 116.7 59.0 55.8 263.9 93.6 117.4 77.6 85.7 83.1 211.8 76.3 78.1 96.8 187.8 87.7 66.4 73.3 101.3 108.2 181.4 123.2 103.2 209.3 177.6 89.5 76.6 97.1 100.7 244.5 202.9 159.0 175.8 102.3 141.6 169.8 37.4 37.3 39.8 44.0 45.9 37.2 37.2 22.9 36.5 46.2 21.8 21.8 29.2 17.2 50.2 35.4 84.8 33.9 38.4 17.3 18.8 20.1 19.8 17.9 20.1 21.1 19.8 20.2 19.3 20.0 21.6 42.2 19.2 20.9 12.1 78.1 145.3 212.5 104.3 48.9 22.9 38.3 22.7 152.0 67.2 61.4 14.7 18.8 88.7 75.0 93.5 3.9 109.2 41.5 58.2 44.9 63.6 142.1 37.6 10.8 85.7 173.0 63.3 41.3 77.5 54.7 29.4 61.1 105.0 149.4 23.5 11.6 122.8 67.1 65.3 130.3 10.8 31.4 59.4 103.2 14.0 33.3 48.5 63.8 12.1 24.5 86.9 88.2 25.9 251.1 136.6 74.6 18.9 47.3 28.4 65.7 63.7 61.3 190.6 100.7 51.1 112.2 195.1 61.7 28.4 106.8 155.8 DNM2 "CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII" ENSG00000079805 "Dynamin 2" P50570 19 10718079-10833488 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Phagocytosis" "Hydrolase, Motor protein" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 242.8;Paneth cells: 177.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054246 Supported Approved "Golgi apparatus,Cytosol" NA NA 230000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Cytosol" "HPA054246: AB_2682427" "unprognostic (2.30e-1)" "unprognostic (5.23e-2)" "unprognostic (4.72e-2)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "prognostic favorable (8.91e-4)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.03e-1)" "unprognostic (3.79e-1)" "unprognostic (1.89e-1)" "unprognostic (4.75e-2)" "unprognostic (5.35e-2)" "unprognostic (5.47e-2)" "unprognostic (5.40e-3)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" 55.1 69.9 50.5 63.2 77.8 125.7 46.1 74.1 64.1 49.0 38.8 105.8 65.9 42.2 25.3 67.6 42.5 40.5 87.2 52.3 57.4 72.8 57.2 87.0 62.4 82.7 78.9 36.6 68.2 38.9 41.9 51.3 79.8 47.4 83.9 30.7 55.0 55.7 108.1 92.8 99.6 35.1 60.3 81.0 98.6 55.1 72.9 58.6 47.6 82.8 65.4 64.6 54.5 101.6 116.4 92.8 67.6 54.6 67.6 65.4 86.5 75.1 70.5 108.8 91.7 94.2 74.7 83.2 132.2 81.5 52.5 99.4 92.6 82.1 90.8 103.1 72.4 160.1 81.7 107.1 82.9 87.8 146.5 67.8 62.4 83.5 77.9 66.2 107.3 84.9 131.5 139.1 68.0 140.1 126.3 85.7 76.6 138.3 109.7 125.6 72.6 95.7 71.3 171.1 97.1 63.8 86.6 73.6 54.2 74.9 58.8 106.2 99.6 120.7 40.5 172.0 102.7 112.7 127.3 77.9 89.9 134.0 61.0 3.5 3.5 7.0 4.0 6.2 3.8 2.5 3.0 4.4 4.2 2.1 1.7 3.0 6.5 8.9 8.4 8.4 3.8 4.1 50.5 77.8 74.1 64.1 52.3 57.4 82.7 78.9 79.8 60.3 72.9 101.6 37.8 32.1 22.3 24.8 48.8 23.2 17.1 13.8 22.2 28.8 19.7 16.3 30.3 14.3 25.7 51.5 22.9 25.7 57.2 242.8 50.9 35.2 48.4 32.2 17.9 33.1 21.6 38.1 29.2 32.0 106.9 19.5 168.7 39.7 19.0 36.8 20.3 22.8 49.1 43.7 31.1 106.9 14.2 28.0 39.6 98.0 16.8 55.2 19.6 60.9 43.4 17.2 39.1 23.1 90.9 45.2 177.3 27.8 92.2 20.2 90.7 38.8 18.0 26.3 26.3 18.7 27.6 15.0 12.3 26.6 31.5 31.7 46.4 40.7 82.5 22.8 DNMT3A ENSG00000119772 "DNA methyltransferase 3 alpha" Q9Y6K1 2 25227855-25342590 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 127.2;Horizontal cells: 95.9;Rod photoreceptor cells: 143.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 59.6;REH: 59.5;SH-SY5Y: 71.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009469, HPA026588" Approved Supported Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB009469: AB_2093990, HPA026588: AB_1847812" "unprognostic (2.38e-1)" "unprognostic (2.94e-1)" "unprognostic (5.65e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (8.38e-2)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-1)" "prognostic favorable (1.18e-4)" "unprognostic (2.35e-2)" "prognostic unfavorable (2.49e-4)" "unprognostic (1.43e-1)" "unprognostic (1.87e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-2)" 5.6 9.0 8.9 9.8 12.6 8.7 6.2 9.3 10.7 9.1 2.4 11.3 6.7 9.3 8.7 6.0 7.5 6.3 5.9 8.8 7.9 11.3 5.3 7.3 11.1 9.0 7.6 13.0 8.3 4.2 11.5 15.7 8.6 7.2 6.6 15.4 6.2 5.9 21.0 4.9 8.9 7.1 5.2 13.4 8.5 5.2 9.4 20.6 6.9 10.2 9.0 7.3 6.2 11.3 1.6 8.1 34.6 8.3 3.8 2.7 45.2 1.9 2.2 4.7 3.8 21.1 13.2 0.0 4.7 4.7 3.5 2.2 3.8 5.2 2.8 5.7 4.3 14.7 12.8 25.4 8.8 2.9 7.6 8.2 2.6 6.0 2.2 9.1 19.5 34.0 18.0 2.9 3.5 20.6 33.7 36.5 59.6 14.3 4.2 59.5 32.5 3.8 2.9 3.4 18.6 71.5 2.7 19.6 6.2 29.5 2.1 16.2 6.8 5.4 4.7 1.0 2.5 5.6 5.1 19.6 2.2 8.4 5.5 2.8 1.0 2.1 2.7 1.7 4.0 1.3 1.7 2.4 1.3 1.6 4.6 3.9 2.5 5.5 2.7 2.3 1.9 1.2 8.9 12.6 9.3 10.7 8.8 7.9 9.0 7.6 8.6 5.2 9.4 11.3 18.5 6.4 13.1 28.1 11.0 5.2 10.2 6.6 5.7 73.3 12.1 9.8 15.8 5.7 9.9 20.2 127.2 40.6 15.3 6.3 5.9 16.9 1.6 13.3 19.1 20.5 13.1 15.8 49.4 9.8 10.7 16.4 9.7 10.7 37.4 37.3 11.0 6.4 23.2 95.9 43.2 11.4 2.0 14.2 3.9 1.9 19.3 13.7 7.2 38.4 7.4 20.6 13.4 36.7 63.4 9.3 9.4 15.4 9.8 12.4 6.2 6.6 7.3 143.5 19.7 15.1 14.3 2.8 14.6 8.1 2.6 32.2 19.6 26.1 12.1 10.2 DOCK6 "KIAA1395, ZIR1" ENSG00000130158 "Dedicator of cytokinesis 6" Q96HP0 19 11199295-11262524 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 70.3;Cardiomyocytes: 185.4;Endothelial cells: 64.8;Hepatic stellate cells: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 68.2;TIME: 68.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049423, HPA049424" Approved Supported Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA049423: AB_2680760, HPA049424: AB_2680761" "unprognostic (2.69e-2)" "unprognostic (2.27e-1)" "unprognostic (9.51e-2)" "unprognostic (3.35e-2)" "unprognostic (4.72e-3)" "prognostic favorable (9.09e-4)" "unprognostic (2.54e-2)" "unprognostic (4.91e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-2)" "unprognostic (2.57e-1)" "unprognostic (7.89e-2)" "unprognostic (1.25e-3)" "unprognostic (2.76e-1)" "unprognostic (1.51e-1)" "unprognostic (5.41e-2)" "unprognostic (2.95e-1)" 31.2 9.9 7.4 5.4 6.3 0.4 27.5 4.5 9.7 15.4 3.6 16.8 14.2 14.7 4.6 16.8 11.6 12.0 29.6 4.6 5.1 26.3 13.2 46.3 4.9 7.8 7.1 12.0 14.4 5.4 11.9 15.0 6.9 14.8 6.2 1.8 11.4 7.5 15.1 25.2 15.4 7.1 5.7 14.5 15.8 5.8 11.4 2.1 29.0 9.3 2.6 14.2 16.6 5.6 14.6 8.9 9.9 8.1 7.3 10.5 15.9 4.2 6.9 4.1 6.3 16.9 11.2 0.9 25.4 7.1 3.9 8.3 4.3 22.3 2.5 12.4 7.0 2.8 2.2 12.8 11.8 4.3 13.7 8.1 13.0 7.5 17.0 7.9 68.2 0.3 15.7 0.0 9.1 32.7 0.1 14.7 12.5 13.2 16.6 0.9 6.7 14.0 6.8 20.0 0.6 17.6 4.2 4.2 7.6 6.5 4.9 7.6 68.8 7.5 7.8 17.1 7.6 1.2 0.2 14.1 6.3 3.2 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 6.3 4.5 9.7 4.6 5.1 7.8 7.1 6.9 5.7 11.4 5.6 70.3 3.2 12.6 6.8 0.9 6.5 6.2 8.5 4.6 1.4 4.3 3.8 185.4 5.7 11.3 25.8 0.0 0.3 0.9 15.6 1.9 5.4 3.5 3.9 8.9 64.8 12.1 0.0 2.9 6.8 1.3 19.6 35.2 7.2 5.1 4.7 55.3 5.6 4.6 0.0 5.9 15.9 8.2 2.5 4.4 1.3 22.4 1.6 3.6 35.6 0.0 4.6 0.0 7.1 3.5 11.9 10.9 9.4 1.9 8.4 11.9 1.9 9.2 2.6 19.7 8.4 30.8 1.5 4.3 7.4 11.5 0.5 1.2 7.8 9.7 9.0 DOK7 "C4orf25, Dok-7, FLJ33718, FLJ39137" ENSG00000175920 "Docking protein 7" Q18PE1 4 3463306-3501473 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 41.9;skeletal muscle: 29.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.1;Enteroendocrine cells: 6.0;Late spermatids: 9.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "memory B-cell: 3.4;naive B-cell: 2.3;NK-cell: 1.9" "Group enriched" "Detected in many" 16 "B-cells: 3.4;NK-cells: 1.9" "Cell line enriched" "Detected in some" 4 "MCF7: 36.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA059449, HPA062780" Approved Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Mitochondria "HPA059449: AB_2684023, HPA062780: AB_2732688" "prognostic favorable (8.45e-5)" "unprognostic (2.34e-1)" "unprognostic (2.08e-2)" "prognostic favorable (2.19e-4)" "unprognostic (5.96e-2)" "unprognostic (6.80e-3)" "unprognostic (1.05e-2)" "unprognostic (9.54e-2)" "unprognostic (1.12e-2)" "unprognostic (5.75e-2)" "unprognostic (2.54e-1)" "unprognostic (8.70e-2)" "unprognostic (1.24e-4)" "unprognostic (4.61e-3)" "unprognostic (5.09e-1)" "unprognostic (3.16e-2)" "prognostic favorable (1.28e-4)" 0.1 0.9 1.0 0.2 4.7 0.2 0.4 7.8 2.9 2.1 11.1 0.3 0.1 1.0 1.7 0.3 5.9 0.3 41.9 1.1 0.9 2.7 1.1 1.6 0.7 4.2 1.5 0.3 5.8 0.1 15.7 0.0 4.7 1.8 0.1 0.0 1.9 1.0 29.5 1.6 1.4 0.0 0.2 1.9 2.7 4.8 3.0 0.0 0.7 8.8 0.4 1.2 0.6 0.0 2.7 0.9 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 2.6 0.0 1.2 0.0 0.1 1.3 0.0 4.4 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 36.2 0.0 1.4 0.3 1.6 0.1 0.0 6.7 0.3 2.3 3.0 0.6 0.1 3.0 0.0 0.0 0.0 8.3 0.1 0.0 0.1 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.0 2.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 1.0 4.7 7.8 2.9 1.1 0.9 4.2 1.5 4.7 0.2 3.0 0.0 0.1 0.0 1.5 1.3 5.3 0.0 3.9 3.7 0.0 0.3 0.7 0.9 17.1 0.0 3.0 5.5 0.0 0.0 0.4 0.5 0.0 2.3 5.8 2.6 0.7 0.1 6.0 2.7 0.4 4.4 0.0 1.4 4.1 2.8 0.0 3.0 0.0 0.1 0.1 0.0 0.9 3.0 2.0 0.0 0.0 9.9 0.9 0.1 0.0 0.0 0.1 0.0 3.1 1.0 0.0 1.8 0.0 0.0 0.0 2.0 0.1 0.3 1.8 0.5 0.0 1.0 0.3 0.2 0.4 0.0 0.0 0.0 0.4 0.1 0.4 1.2 DONSON "B17, C21orf60, C2TA, DKFZP434M035" ENSG00000159147 "DNA replication fork stabilization factor DONSON" Q9NYP3 21 33559542-33588706 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 57.3;Erythroid cells: 42.1;Spermatocytes: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039558, HPA049033" Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cell Junctions" Cytosol "HPA039558: AB_2676570, HPA049033: AB_2680608" "unprognostic (9.90e-3)" "unprognostic (1.01e-3)" "unprognostic (6.58e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (8.22e-4)" "unprognostic (4.00e-2)" "unprognostic (5.93e-3)" "prognostic favorable (2.17e-4)" "unprognostic (1.25e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.77e-2)" "unprognostic (1.66e-1)" "unprognostic (2.07e-1)" "unprognostic (8.83e-2)" 5.5 2.9 5.8 5.5 6.5 10.9 4.1 7.9 7.5 8.5 4.2 5.2 5.4 5.7 2.4 5.0 7.0 5.5 4.4 5.4 6.5 3.9 7.9 4.6 10.5 6.7 6.2 10.8 3.4 5.6 5.5 6.6 6.7 4.8 6.3 13.3 3.5 3.4 4.4 8.5 6.1 4.5 5.7 3.6 4.9 21.2 6.5 10.6 3.5 4.8 9.2 4.7 6.2 8.6 67.9 15.5 34.8 30.4 10.7 18.5 23.9 53.7 23.2 41.2 45.1 41.9 19.7 40.5 13.9 28.3 30.6 20.0 43.6 20.2 45.1 36.5 36.5 73.8 34.9 41.5 8.1 39.0 18.2 13.9 5.7 44.4 11.1 13.1 25.1 19.8 67.0 65.2 35.4 14.7 34.0 17.2 35.9 34.8 17.3 33.2 68.4 41.3 21.3 19.0 36.0 14.8 82.1 25.3 23.1 17.1 34.9 19.4 16.4 38.0 25.3 28.6 37.7 56.8 58.1 59.3 22.1 52.1 43.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 6.5 7.9 7.5 5.4 6.5 6.7 6.2 6.7 5.7 6.5 8.6 6.3 3.2 1.9 10.4 4.8 8.2 8.1 3.1 5.2 2.8 5.6 5.7 3.9 7.2 2.3 3.7 10.4 13.2 7.8 3.0 1.9 3.3 57.3 3.0 6.6 8.0 1.2 42.1 9.7 4.7 27.9 6.9 7.1 4.4 8.2 7.5 7.5 6.2 8.9 6.7 11.2 4.2 6.1 3.4 6.3 25.3 10.2 5.5 7.2 4.7 4.0 2.1 4.1 7.5 12.7 3.9 2.5 13.9 19.3 5.7 2.9 4.4 2.8 3.6 0.0 4.4 7.6 62.3 33.5 7.6 9.8 16.6 7.6 3.0 6.8 9.2 DPF2 "BAF45d, REQ, ubi-d4" ENSG00000133884 "Double PHD fingers 2" Q92785 11 65333852-65354262 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020880, HPA056786" Approved Supported Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA020880: AB_1847845, HPA056786: AB_2683235" "unprognostic (2.06e-1)" "unprognostic (2.13e-1)" "unprognostic (3.45e-2)" "unprognostic (2.90e-3)" "unprognostic (1.40e-2)" "unprognostic (9.66e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (2.04e-1)" "unprognostic (3.29e-2)" "unprognostic (3.07e-1)" "unprognostic (2.43e-1)" "unprognostic (1.33e-1)" "unprognostic (6.93e-2)" "unprognostic (3.04e-2)" "unprognostic (3.24e-1)" "unprognostic (1.26e-2)" "unprognostic (1.34e-1)" 21.2 21.0 41.3 14.2 45.1 24.7 21.6 43.6 43.3 35.0 35.2 36.1 13.1 37.6 22.8 23.1 31.3 14.7 34.2 39.5 42.2 20.8 16.8 19.5 22.3 43.1 43.7 40.9 20.5 19.7 20.1 17.6 42.8 28.6 13.8 17.6 21.1 25.8 38.6 19.3 24.3 27.8 43.7 29.7 24.2 37.7 43.0 37.6 22.5 29.2 24.5 34.2 24.1 48.7 29.9 36.4 45.9 40.5 39.7 39.8 25.5 25.0 35.1 53.5 38.6 36.0 34.8 39.5 40.8 34.0 46.6 31.2 52.2 31.9 37.7 47.6 23.1 50.4 24.6 37.7 61.1 47.0 36.5 35.0 30.4 48.4 86.6 40.1 43.3 47.0 48.7 51.0 35.2 47.3 60.0 49.3 51.6 31.9 37.4 65.1 29.9 46.8 34.0 24.1 29.9 27.3 32.1 45.7 47.0 29.7 59.0 26.2 25.8 35.2 31.3 38.9 25.9 62.7 78.8 51.1 21.6 30.6 40.4 186.4 75.4 141.1 79.7 70.8 87.0 102.0 76.9 78.4 76.2 109.1 78.6 71.9 161.5 125.8 83.0 70.6 107.3 108.4 41.3 45.1 43.6 43.3 39.5 42.2 43.1 43.7 42.8 43.7 43.0 48.7 19.2 6.4 10.1 14.0 35.7 22.7 21.8 41.7 23.9 42.2 20.1 24.9 12.7 27.1 24.2 33.1 47.9 27.2 42.0 11.5 19.6 21.2 5.2 18.3 29.5 24.2 17.4 32.8 18.5 17.4 22.9 27.2 15.3 18.5 16.5 31.8 24.3 13.3 19.5 30.3 19.9 16.8 32.6 17.5 33.8 12.3 58.7 16.9 19.6 15.0 30.0 22.8 35.0 24.1 32.3 19.3 8.6 53.4 21.6 22.6 23.7 22.0 19.3 50.5 32.9 28.8 32.2 60.2 63.5 15.4 23.2 26.5 30.6 28.7 17.9 19.7 DPH1 "DPH2L, DPH2L1, OVCA1" ENSG00000108963 "Diphthamide biosynthesis 1" Q9BZG8 17 2030137-2043898 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism, Ectodermal dysplasia, Hypotrichosis, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 19.4;Gastric mucus-secreting cells: 21.4;Plasma cells: 12.0;Squamous epithelial cells: 13.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069750, HPA073864" Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Cell Junctions" "HPA069750: AB_2686188, HPA073864: " "unprognostic (5.54e-2)" "unprognostic (1.99e-1)" "unprognostic (1.62e-1)" "unprognostic (1.86e-2)" "unprognostic (1.50e-2)" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "prognostic favorable (1.78e-5)" "unprognostic (2.74e-3)" "unprognostic (2.10e-2)" "unprognostic (1.03e-1)" "unprognostic (3.40e-1)" "unprognostic (7.30e-2)" "unprognostic (1.41e-1)" 24.5 32.3 13.1 6.0 12.8 5.3 22.2 16.8 17.7 29.1 10.7 26.8 8.0 28.8 5.6 19.8 31.0 9.1 19.2 13.7 11.9 28.0 36.3 16.6 7.5 10.3 10.9 26.6 32.0 14.2 59.3 8.5 10.3 36.2 6.2 12.4 23.7 11.0 42.3 29.3 20.8 8.9 10.1 24.3 27.0 20.3 11.7 6.7 28.6 13.7 6.0 24.2 22.3 11.5 15.4 24.9 6.3 16.0 22.2 14.2 18.7 19.3 26.8 29.7 18.7 24.1 11.6 29.0 23.6 52.5 11.2 11.6 20.7 21.1 15.9 9.0 52.4 6.3 10.5 13.1 19.4 8.3 10.2 20.3 20.3 22.7 19.0 20.5 13.9 16.8 23.4 11.2 11.9 18.2 14.7 4.8 6.5 17.3 25.9 16.6 5.7 22.0 13.3 8.0 13.1 15.2 17.4 17.9 17.2 6.9 25.9 6.8 10.1 19.4 10.1 26.2 16.7 10.3 8.3 6.8 20.3 10.8 8.5 0.8 4.5 0.8 8.0 6.1 8.9 8.8 6.5 7.4 7.7 7.2 9.6 6.9 0.3 6.7 4.5 5.5 10.2 5.2 13.1 12.8 16.8 17.7 13.7 11.9 10.3 10.9 10.3 10.1 11.7 11.5 0.9 3.2 9.2 1.3 9.3 0.4 0.9 0.5 19.4 2.1 0.8 0.8 1.5 0.0 2.7 0.0 2.1 1.4 0.9 0.6 0.0 0.5 1.2 1.5 1.2 1.7 0.0 9.0 4.0 0.6 0.9 4.5 21.4 0.8 2.5 1.0 0.7 0.0 0.6 1.7 3.7 0.8 0.0 0.0 0.8 1.5 0.6 3.9 0.0 1.0 0.4 0.9 2.1 1.5 1.4 0.0 0.2 0.4 12.0 0.5 0.5 0.5 3.0 2.8 0.0 1.3 3.2 1.2 0.5 13.0 0.3 1.4 5.4 1.3 0.4 0.6 DSE "DS-Epi1, DSEPI, SART2" ENSG00000111817 "Dermatan sulfate epimerase" Q9UL01 6 116254173-116444861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 112.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 5.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014764 Uncertain "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "HPA014764: AB_1856587" "unprognostic (1.28e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (3.23e-3)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.02e-2)" "unprognostic (7.81e-2)" "prognostic unfavorable (6.34e-4)" "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (6.19e-3)" "unprognostic (2.54e-2)" "unprognostic (2.06e-1)" "unprognostic (1.10e-2)" 27.8 10.7 3.6 26.8 4.5 18.4 18.3 3.9 4.4 13.8 10.4 7.7 6.4 10.5 8.3 13.7 14.6 14.9 12.4 3.2 4.3 8.6 11.3 15.3 16.4 7.0 5.8 13.8 3.8 11.1 6.0 23.1 5.6 8.5 8.0 3.5 6.9 10.2 6.9 13.8 9.0 15.0 4.6 18.6 6.4 6.1 8.5 10.3 6.6 10.7 9.7 19.7 14.3 5.9 32.7 7.0 23.6 22.2 62.0 40.7 26.5 37.6 88.2 46.4 67.4 0.2 8.9 0.9 3.3 66.3 46.4 60.8 3.3 88.7 60.1 33.9 14.6 2.2 9.8 0.3 69.0 1.5 1.7 86.8 37.4 51.5 50.0 24.0 27.7 8.3 0.8 14.4 22.4 1.0 4.4 1.8 12.7 0.2 1.8 5.6 21.6 15.6 30.4 2.2 7.8 5.9 36.4 0.1 0.8 16.2 0.3 3.9 10.5 46.4 13.4 11.8 30.6 3.1 1.1 1.6 24.6 4.0 5.5 0.4 2.0 0.1 0.6 2.5 0.3 2.0 0.5 0.3 5.9 2.1 0.6 0.3 1.6 0.1 1.6 2.7 0.1 0.8 3.6 4.5 3.9 4.4 3.2 4.3 7.0 5.8 5.6 4.6 8.5 5.9 9.4 16.0 4.1 64.9 15.4 52.0 26.4 42.2 78.6 6.3 7.4 10.7 8.3 2.8 20.7 3.7 0.0 2.9 16.5 0.3 7.9 4.8 52.2 11.0 21.9 15.4 1.2 11.4 46.8 8.5 7.0 73.7 3.6 3.1 22.8 100.9 56.4 5.7 39.8 1.7 48.9 0.6 8.2 83.6 77.1 24.9 55.0 112.2 10.6 51.5 79.4 3.4 5.2 73.4 86.4 13.6 0.4 30.1 8.9 32.0 0.4 7.7 30.3 3.0 32.9 16.4 33.4 6.1 5.5 76.6 39.9 4.9 14.0 17.2 1.0 51.0 DSG1 "CDHF4, DSG" ENSG00000134760 "Desmoglein 1" Q02413 18 31318160-31359246 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 564.4" "Group enriched" "Detected in some" 25 "Basal keratinocytes: 117.4;Suprabasal keratinocytes: 315.7" "Group enriched" "Detected in many" 10 "head and neck cancer: 57.0;melanoma: 16.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 23 "hTCEpi: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA022128, HPA074188" Enhanced NA NA 130000000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "HPA022128: AB_1847620, HPA074188: " "unprognostic (2.55e-2)" "unprognostic (8.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.13e-1)" "unprognostic (5.22e-1)" "unprognostic (1.81e-2)" "unprognostic (1.57e-2)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (2.19e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-3)" "unprognostic (2.87e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.99e-4)" 0.4 0.0 0.0 0.0 0.0 0.2 24.7 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.1 1.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.6 0.0 2.0 564.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 2.1 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.4 0.0 0.0 0.6 0.0 3.3 0.9 1.7 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.1 0.1 0.0 0.0 8.6 3.5 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.9 0.2 6.5 315.7 0.0 0.2 0.0 0.1 0.0 DSP "DPI, DPII, KPPS2, PPKS2" ENSG00000096696 Desmoplakin P15924 6 7541617-7586714 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 460.7;skin 1: 854.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 902.0;Cardiomyocytes: 729.7;Squamous epithelial cells: 1657.5;Suprabasal keratinocytes: 2018.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 314.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 2.0" "Lineage enriched" "Detected in single" 20 "B-cells: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 278.0;HaCaT: 302.6;HBEC3-KT: 217.5;hTCEpi: 666.3;SuSa: 204.1" "Region enriched" "Detected in single" 23 "hippocampal formation: 11.6" "Region enhanced" "Detected in many" "spinal cord: 9.5" "CAB037324, HPA045840, HPA054950" Enhanced Supported "Cell Junctions" NA NA 100000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "CAB037324: , HPA045840: AB_2679468, HPA054950: AB_2682645" "unprognostic (1.65e-1)" "unprognostic (3.09e-1)" "unprognostic (6.13e-2)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.82e-2)" "unprognostic (7.03e-3)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (5.02e-2)" "unprognostic (2.94e-2)" "prognostic favorable (1.53e-9)" "unprognostic (2.45e-1)" "unprognostic (2.88e-1)" "unprognostic (8.38e-2)" "prognostic unfavorable (1.82e-4)" 5.2 11.6 4.2 7.0 1.8 0.6 65.8 2.5 3.5 151.0 19.3 46.0 52.0 5.4 27.5 460.7 16.3 7.8 84.9 3.4 0.9 22.4 41.9 6.1 3.7 1.6 2.0 2.0 111.5 54.9 9.0 63.3 1.5 29.9 43.5 21.2 125.1 11.7 3.4 854.8 42.3 2.9 2.4 3.2 48.1 1.5 2.2 37.1 41.5 0.6 78.7 13.1 286.1 0.9 132.2 38.9 0.0 0.1 5.6 8.2 278.0 25.5 21.8 12.4 12.0 110.8 33.5 0.1 35.8 40.9 10.0 302.6 46.1 217.5 2.2 0.1 54.1 0.0 21.5 149.5 0.0 0.6 0.9 1.9 666.3 11.0 121.7 30.0 0.0 0.6 0.2 0.2 22.0 61.4 0.1 1.0 5.6 62.6 19.6 0.1 0.1 32.9 45.3 34.8 12.6 0.3 28.5 59.9 0.2 204.1 71.0 0.3 0.0 4.8 1.2 0.3 0.3 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 1.8 2.5 3.5 3.4 0.9 1.6 2.0 1.5 2.4 2.2 0.9 7.6 51.3 17.0 0.0 7.5 902.0 164.5 157.3 278.3 4.4 184.5 126.4 729.7 97.2 197.5 60.7 14.6 273.0 1.2 357.1 1.9 160.6 1.8 306.5 42.4 46.9 174.6 0.0 0.1 111.9 273.1 51.2 237.0 560.1 3.8 532.2 4.6 186.6 27.5 0.0 0.9 204.7 111.9 1.9 77.8 1.3 0.9 5.9 101.4 3.7 2.6 14.7 0.0 0.0 0.1 167.4 284.2 0.0 5.7 204.0 180.7 12.0 176.6 28.6 0.0 0.4 67.4 1.3 2.7 1657.5 2018.0 385.7 8.1 0.3 247.8 269.9 DSTYK "DustyPK, KIAA0472, RIP5, RIPK5, SPG23" ENSG00000133059 "Dual serine/threonine and tyrosine protein kinase" Q6XUX3 1 205142505-205211702 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 89.2;Melanocytes: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044140 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "HPA044140: AB_10965031" "unprognostic (1.42e-2)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (1.02e-3)" "unprognostic (1.39e-1)" "unprognostic (2.66e-1)" "unprognostic (1.43e-2)" "unprognostic (9.01e-2)" "unprognostic (1.81e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (3.26e-2)" "unprognostic (7.80e-2)" "unprognostic (1.93e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (8.73e-5)" 4.5 7.2 11.5 3.8 11.1 19.2 6.7 11.5 12.1 6.4 6.8 6.0 2.7 7.9 5.8 5.5 7.2 4.5 4.9 11.8 11.3 7.5 2.2 6.1 4.0 13.5 10.7 11.1 4.5 13.1 5.5 6.0 13.7 5.6 3.6 13.5 4.4 6.9 9.6 12.0 4.1 7.1 9.9 6.2 4.2 5.1 11.5 6.2 6.8 6.8 4.5 5.2 5.4 13.5 9.9 6.3 6.6 8.1 9.5 15.9 4.7 12.0 12.1 12.4 8.4 2.9 5.3 7.3 3.5 20.6 6.9 6.9 7.3 7.8 12.4 3.5 7.8 13.3 8.1 3.1 8.5 3.7 6.8 9.4 11.6 12.7 12.0 14.7 9.2 5.2 17.4 4.8 10.0 6.8 2.9 3.3 7.2 1.8 7.4 2.6 12.1 6.5 8.4 6.1 3.7 7.2 10.3 10.5 34.5 7.7 7.8 4.9 9.2 7.7 7.7 11.8 8.2 4.8 3.7 4.1 9.0 5.1 28.2 8.1 1.9 3.6 2.4 1.5 2.3 1.5 1.8 2.0 1.7 1.7 2.6 1.9 2.7 2.8 1.0 1.2 1.1 1.0 11.5 11.1 11.5 12.1 11.8 11.3 13.5 10.7 13.7 9.9 11.5 13.5 15.8 28.9 15.5 26.4 15.3 14.9 7.2 10.5 14.2 48.0 14.5 13.6 13.6 12.8 15.1 16.5 33.3 6.8 15.1 3.8 5.9 12.5 11.3 16.3 37.7 16.1 12.7 31.6 35.1 9.1 6.1 19.4 8.2 11.6 24.1 43.2 28.5 6.9 8.8 89.2 36.6 6.2 6.1 23.6 15.6 25.2 16.4 11.4 90.7 21.5 20.6 45.1 23.7 17.1 43.0 10.6 5.0 18.0 11.1 10.7 6.1 6.9 24.7 37.3 26.3 22.4 16.4 22.3 13.0 10.1 13.9 2.6 15.1 27.8 7.5 6.7 DVL1 ENSG00000107404 "Dishevelled segment polarity protein 1" O14640 1 1335276-1349418 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 230.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "PC-3: 154.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011538, HPA073607" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB011538: AB_2093326, HPA073607: " "unprognostic (2.67e-1)" "unprognostic (4.34e-3)" "unprognostic (2.13e-3)" "unprognostic (2.05e-2)" "unprognostic (9.58e-2)" "unprognostic (1.51e-1)" "unprognostic (2.81e-3)" "unprognostic (5.03e-3)" "unprognostic (1.78e-2)" "unprognostic (2.96e-2)" "unprognostic (1.62e-3)" "unprognostic (5.35e-2)" "unprognostic (4.03e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.33e-4)" "unprognostic (2.34e-2)" "unprognostic (2.55e-2)" 32.8 49.9 50.6 11.8 44.4 9.6 34.0 32.0 71.4 42.9 23.1 50.4 28.8 37.6 8.3 65.0 42.7 11.7 74.9 51.6 31.9 38.2 56.8 35.4 9.5 42.2 37.7 43.0 63.9 21.2 43.7 15.0 35.4 39.4 5.8 8.1 61.8 14.3 230.1 51.5 32.4 7.9 31.9 28.9 53.1 61.9 37.9 6.8 38.3 69.9 4.7 43.6 46.2 41.1 81.5 40.7 16.5 35.2 15.7 19.1 40.5 48.3 22.8 37.3 18.7 31.7 99.3 25.3 70.8 21.5 20.6 48.9 13.2 49.1 5.8 31.4 76.6 14.4 78.4 58.1 33.6 22.5 21.7 16.3 29.6 50.2 34.2 31.7 12.9 33.9 56.5 17.5 15.6 32.6 21.8 37.4 26.3 29.0 154.3 36.9 13.0 44.7 27.5 12.6 64.3 43.8 23.3 62.6 66.6 5.9 34.8 37.4 25.8 21.2 55.0 82.4 82.2 27.6 12.1 32.1 62.2 31.3 13.7 0.1 0.3 0.0 0.2 0.3 0.2 0.3 0.2 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.2 0.3 0.1 0.1 50.6 44.4 32.0 71.4 51.6 31.9 42.2 37.7 35.4 31.9 37.9 41.1 20.5 19.2 14.8 12.1 4.4 13.8 5.5 8.8 6.2 33.2 19.0 16.3 25.5 8.6 10.1 7.3 6.2 10.7 6.9 32.1 3.9 11.3 1.1 13.4 14.2 12.0 12.1 1.3 11.0 20.4 14.9 11.5 31.6 18.8 1.3 15.8 6.1 21.8 5.1 32.0 10.2 17.6 4.1 5.7 6.8 3.0 13.1 4.9 7.2 9.4 2.6 23.5 1.0 6.0 14.3 52.3 20.8 10.5 5.1 16.6 21.0 5.8 9.1 22.1 13.1 12.2 10.8 14.2 13.3 15.3 15.5 11.4 4.5 25.4 24.3 12.6 DVL3 KIAA0208 ENSG00000161202 "Dishevelled segment polarity protein 3" Q92997 3 184155377-184173614 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046486, HPA058265" Approved Approved "Intermediate filaments,Midbody ring,Centrosome" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" "Midbody ring, Centrosome" "Intermediate filaments" "CAB046486: AB_10610845, HPA058265: AB_2683658" "unprognostic (2.20e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.88e-2)" "unprognostic (1.64e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.41e-4)" "unprognostic (8.61e-2)" "unprognostic (5.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (4.77e-5)" "prognostic unfavorable (1.53e-8)" "unprognostic (1.87e-1)" "unprognostic (4.10e-1)" "unprognostic (8.41e-2)" "unprognostic (3.95e-1)" 35.2 28.1 16.4 18.7 17.4 18.6 29.8 17.4 18.9 39.0 15.9 46.0 17.2 44.7 16.1 30.3 34.5 22.6 35.0 16.4 17.1 25.7 20.0 31.7 13.9 18.1 17.3 42.0 25.6 17.9 24.4 38.3 17.6 29.1 16.1 22.8 25.6 25.8 34.9 33.8 27.1 31.7 16.6 25.6 27.9 15.1 17.0 12.4 30.0 22.3 15.9 36.6 31.6 18.3 47.9 13.6 36.4 41.4 37.5 37.8 95.0 28.4 28.9 32.7 27.6 43.6 18.3 33.6 73.3 37.0 32.4 40.8 29.6 22.2 23.4 54.0 32.2 38.1 21.3 28.2 56.6 21.2 27.8 38.4 39.9 23.4 27.3 55.9 24.6 21.6 38.9 44.2 35.5 46.5 28.3 25.2 32.8 34.6 22.1 49.9 42.7 30.0 31.7 36.2 36.3 51.0 34.9 39.8 67.4 35.8 98.7 26.8 25.0 29.5 28.5 31.0 43.8 48.3 38.8 37.0 30.0 22.4 23.6 0.1 0.6 1.3 0.6 1.0 0.8 0.7 0.4 0.7 0.6 0.5 0.5 0.3 0.9 0.4 0.3 0.8 0.2 0.4 16.4 17.4 17.4 18.9 16.4 17.1 18.1 17.3 17.6 16.6 17.0 18.3 15.9 25.6 14.1 16.6 10.8 18.7 15.7 12.9 15.9 20.1 23.5 16.5 26.9 12.8 17.2 22.0 27.1 34.4 14.6 40.8 23.5 13.3 12.8 23.2 30.9 15.9 34.3 6.9 11.4 16.6 21.6 22.6 32.6 27.7 17.1 29.7 19.2 20.5 20.3 62.2 11.8 22.3 12.2 16.2 14.4 47.5 33.5 17.4 12.4 14.0 10.8 19.7 14.4 9.0 11.5 20.7 18.9 37.2 13.9 20.8 25.2 18.3 13.4 18.5 19.7 23.6 27.1 10.6 12.4 20.4 21.7 52.1 10.3 21.9 21.5 25.7 DYM "DMC, FLJ20071, SMC" ENSG00000141627 Dymeclin Q7RTS9 18 49036387-49461347 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 113.6;Early spermatids: 353.4;Excitatory neurons: 173.2;Inhibitory neurons: 204.1;Late spermatids: 176.1;Microglial cells: 149.9;Oligodendrocyte precursor cells: 167.9;Oligodendrocytes: 299.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043551, HPA049187" Approved Supported "Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Golgi apparatus" "HPA043551: AB_2678547, HPA049187: AB_2680668" "unprognostic (1.88e-2)" "unprognostic (1.23e-1)" "unprognostic (3.12e-3)" "unprognostic (1.33e-2)" "unprognostic (1.95e-1)" "unprognostic (1.59e-1)" "unprognostic (1.85e-3)" "unprognostic (1.77e-1)" "unprognostic (1.72e-1)" "unprognostic (8.30e-3)" "unprognostic (2.53e-2)" "unprognostic (2.58e-2)" "prognostic favorable (2.76e-5)" "unprognostic (3.89e-1)" "unprognostic (1.69e-1)" "unprognostic (4.26e-3)" "prognostic unfavorable (5.26e-5)" 17.9 19.2 17.3 14.8 19.6 24.0 23.3 24.9 20.4 24.9 24.4 20.7 15.8 19.8 20.2 25.3 18.6 17.7 21.1 16.7 20.4 21.1 19.7 15.7 17.0 22.8 21.1 29.4 80.7 28.6 9.9 14.6 24.5 20.6 16.8 36.0 36.6 22.0 49.6 18.2 14.1 25.1 19.0 12.7 16.6 44.0 19.1 33.0 32.6 46.0 20.7 23.2 22.3 23.9 32.9 19.8 30.6 47.0 56.9 63.9 24.1 32.2 42.1 37.7 36.8 14.6 20.7 102.1 27.8 60.1 27.9 41.0 48.1 42.1 46.0 38.6 24.7 23.8 16.9 43.4 56.7 83.5 41.5 50.1 49.1 44.1 112.7 63.3 59.0 51.6 25.7 60.5 30.4 35.0 56.5 35.5 9.8 27.1 15.2 29.2 39.2 48.3 34.8 37.2 56.5 36.5 21.9 26.1 30.2 34.5 36.7 29.8 32.6 35.6 16.9 15.5 18.9 67.8 52.7 57.4 19.1 51.6 40.5 20.9 26.9 32.7 20.2 23.4 27.2 17.0 19.3 18.7 29.2 13.9 19.6 15.2 11.9 30.6 20.6 8.4 21.4 21.4 17.3 19.6 24.9 20.4 16.7 20.4 22.8 21.1 24.5 19.0 19.1 23.9 16.0 6.4 6.9 113.6 29.1 11.6 20.4 8.1 29.0 20.1 17.9 15.4 24.5 17.2 8.4 3.7 6.2 19.5 17.4 10.5 13.7 18.1 353.4 11.6 17.2 16.3 16.2 17.9 173.2 20.3 22.2 20.6 17.3 14.8 16.5 23.3 14.3 11.5 16.7 21.9 204.1 15.1 6.1 23.0 15.1 176.1 27.7 20.5 3.6 149.9 19.7 16.1 24.7 167.9 299.4 14.7 11.4 27.1 23.8 25.0 16.1 22.5 13.4 24.9 13.1 22.4 15.4 49.8 16.2 19.4 11.4 35.2 21.6 18.1 16.2 20.2 DYNC2H1 "DHC1b, DHC2, DNCH2, DYH1B, hdhc11" ENSG00000187240 "Dynein cytoplasmic 2 heavy chain 1" Q8NCM8 11 103109410-103479863 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Motor protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 173.7;Cone photoreceptor cells: 112.6;Endometrial ciliated cells: 124.0;Excitatory neurons: 164.7;Inhibitory neurons: 101.8;Respiratory ciliated cells: 171.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039015, HPA039016" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Nucleoplasm, Cytosol" "HPA039015: AB_2676309, HPA039016: AB_10673410" "unprognostic (3.11e-1)" "unprognostic (2.60e-1)" "unprognostic (1.28e-2)" "unprognostic (1.54e-1)" "unprognostic (7.11e-2)" "unprognostic (2.08e-1)" "unprognostic (4.14e-3)" "unprognostic (2.07e-2)" "unprognostic (2.05e-1)" "unprognostic (4.10e-2)" "unprognostic (2.87e-2)" "unprognostic (7.13e-2)" "prognostic favorable (8.49e-5)" "unprognostic (3.75e-3)" "unprognostic (1.62e-1)" "unprognostic (3.88e-2)" "unprognostic (4.11e-3)" 4.2 3.0 5.0 1.2 5.2 0.3 3.5 5.6 10.2 5.1 14.6 3.2 1.6 4.6 3.7 1.6 6.5 3.2 2.0 4.1 6.1 3.7 0.8 2.8 0.9 8.3 8.9 5.6 2.9 6.7 6.8 1.4 6.3 2.6 0.7 10.5 2.6 2.5 0.8 2.8 2.1 2.3 5.5 1.9 2.2 7.9 6.7 1.8 4.6 1.5 0.7 3.3 3.0 5.9 1.3 2.7 7.0 3.3 9.5 21.2 0.4 4.0 6.4 6.5 7.0 1.6 1.5 0.0 5.5 8.0 3.1 5.5 5.5 7.7 5.3 0.0 4.6 1.2 4.8 0.2 9.3 2.2 1.3 13.6 2.8 14.9 16.9 10.3 2.7 1.4 0.2 0.0 8.6 5.4 0.7 0.7 1.9 0.0 7.7 0.0 5.9 0.1 7.5 0.9 4.6 3.6 6.5 1.7 3.1 1.7 6.8 1.5 6.4 7.9 3.3 7.7 3.0 0.0 0.0 0.1 2.3 6.7 2.4 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 5.0 5.2 5.6 10.2 4.1 6.1 8.3 8.9 6.3 5.5 6.7 5.9 12.7 0.0 13.1 173.7 2.3 6.6 13.4 17.3 9.6 25.9 8.2 9.7 10.1 4.3 18.0 27.6 112.6 0.3 2.1 0.2 1.9 7.0 26.1 124.0 43.7 11.1 17.3 1.3 164.7 3.4 0.5 32.0 5.6 7.5 3.8 15.4 9.3 0.8 2.5 32.0 101.8 1.0 4.1 0.8 5.8 11.1 20.8 3.1 8.8 45.0 0.9 16.5 1.0 86.0 72.6 10.5 2.9 18.4 3.3 4.9 0.9 16.9 171.0 85.1 19.7 40.8 18.5 90.6 11.6 5.0 5.5 0.5 5.0 23.5 1.7 5.9 DYNC2I1 "CFAP163, DIC6, FAP163, FLJ10300, WDR60" ENSG00000126870 "Dynein 2 intermediate chain 1" Q8WVS4 7 158856558-158956747 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 45.7;Cardiomyocytes: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020607, HPA021316" Approved Supported Centrosome NA NA "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Centrosome "HPA020607: AB_1858817, HPA021316: AB_2215577" "unprognostic (1.22e-1)" "unprognostic (3.17e-2)" "unprognostic (2.05e-1)" "unprognostic (9.18e-3)" "unprognostic (3.07e-2)" "unprognostic (1.03e-1)" "unprognostic (5.88e-2)" "unprognostic (1.94e-1)" "unprognostic (3.58e-2)" "unprognostic (4.07e-2)" "unprognostic (4.13e-2)" "unprognostic (9.23e-2)" "unprognostic (3.11e-2)" "unprognostic (1.41e-1)" "unprognostic (1.89e-1)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" 13.0 7.4 5.7 5.5 4.0 5.6 9.9 6.5 12.3 9.4 16.3 13.4 9.2 9.1 9.3 6.5 13.6 7.0 15.1 3.9 3.7 8.2 3.7 8.8 5.3 5.5 2.5 9.8 5.9 12.8 9.0 6.8 4.7 6.8 6.1 14.1 8.2 6.3 24.1 7.0 10.2 7.3 0.2 7.5 8.0 40.1 4.7 5.8 10.9 10.0 3.5 9.7 7.7 9.1 15.2 15.0 10.4 25.0 7.9 7.6 4.6 9.4 8.3 7.6 8.2 7.3 13.5 6.0 14.3 5.8 9.3 7.1 4.8 10.1 8.5 6.5 9.6 8.0 10.2 3.3 8.0 9.2 17.8 6.3 7.4 5.9 2.5 17.9 6.3 4.3 24.4 3.3 8.9 8.9 15.4 8.2 9.1 5.7 9.7 13.7 10.7 7.3 12.7 7.7 20.8 14.7 19.1 11.5 11.4 9.0 8.4 5.6 7.8 9.5 3.4 31.2 6.9 8.7 10.2 12.9 26.0 8.8 14.4 49.8 8.6 4.7 13.5 5.7 11.9 21.5 10.5 11.3 5.4 22.7 10.1 10.3 5.3 10.3 5.8 42.6 5.4 2.6 5.7 4.0 6.5 12.3 3.9 3.7 5.5 2.5 4.7 0.2 4.7 9.1 45.7 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.5 0.0 0.0 0.0 0.0 15.6 14.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 13.7 11.7 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 11.5 1.8 0.0 0.0 0.0 DYNC2I2 "bA216B9.3, CFAP133, DIC5, FAP133, MGC20486, WDR34" ENSG00000119333 "Dynein 2 intermediate chain 2" Q96EX3 9 128633653-128656847 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 20.4;Cytotrophoblasts: 89.8;Extravillous trophoblasts: 95.3;Hofbauer cells: 21.9;Syncytiotrophoblasts: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 35.8;naive B-cell: 52.9" "Lineage enriched" "Detected in all" 5 "B-cells: 52.9" "Cell line enhanced" "Detected in all" "MCF7: 432.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040764, HPA041091" Approved Approved Cytosol NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA040764: AB_10795625, HPA041091: AB_10796237" "unprognostic (1.45e-1)" "prognostic favorable (1.63e-4)" "unprognostic (2.55e-1)" "prognostic favorable (7.01e-5)" "unprognostic (2.27e-1)" "unprognostic (7.00e-3)" "prognostic unfavorable (8.79e-4)" "unprognostic (6.04e-2)" "unprognostic (4.39e-1)" "unprognostic (3.65e-1)" "unprognostic (8.55e-2)" "unprognostic (1.04e-1)" "unprognostic (3.57e-3)" "unprognostic (2.06e-2)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (1.28e-1)" 14.4 49.9 15.7 11.4 15.4 33.2 20.1 14.3 20.1 28.2 30.5 26.7 22.2 22.4 8.9 37.9 30.5 11.1 41.4 15.4 18.9 61.8 39.1 25.1 12.0 17.0 19.4 19.1 36.7 21.2 36.1 11.0 16.4 31.0 10.3 4.5 31.9 14.0 11.1 24.0 27.7 6.3 16.5 23.6 26.3 69.8 16.6 23.8 55.6 4.3 9.5 19.2 23.7 14.7 112.7 202.8 49.8 78.8 11.4 16.1 141.4 46.2 32.9 66.5 42.8 96.6 197.3 40.4 32.4 30.8 62.0 169.4 47.5 50.8 16.6 93.5 40.1 24.0 134.8 52.0 13.9 41.5 39.4 8.0 25.0 66.3 18.9 24.0 46.5 112.6 83.5 34.0 36.4 432.4 151.3 106.1 63.7 97.3 121.0 157.2 66.6 136.8 42.1 36.0 125.1 100.1 143.9 135.9 36.8 13.7 230.5 40.7 28.3 75.9 114.8 95.6 90.7 34.6 100.7 39.6 71.4 41.9 74.0 1.7 1.1 0.4 1.4 1.6 2.3 35.8 2.9 3.9 2.8 52.9 1.1 1.7 0.8 4.5 5.7 11.0 5.7 3.8 15.7 15.4 14.3 20.1 15.4 18.9 17.0 19.4 16.4 16.5 16.6 14.7 2.7 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 89.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 95.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 37.4 0.2 0.0 0.0 0.0 DYNC2LI1 "CGI-60, D2LIC, DKFZP564A033, LIC3" ENSG00000138036 "Dynein cytoplasmic 2 light intermediate chain 1" Q8TCX1 2 43774039-43810010 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Motor protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 197.5;Respiratory ciliated cells: 133.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 110.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062905 Approved Supported Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA062905: AB_2684899" "unprognostic (3.46e-1)" "unprognostic (3.25e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-2)" "unprognostic (2.89e-2)" "unprognostic (4.05e-2)" "unprognostic (1.84e-3)" "unprognostic (9.85e-2)" "unprognostic (2.87e-2)" "unprognostic (1.22e-1)" "unprognostic (1.85e-2)" "unprognostic (1.91e-1)" "prognostic favorable (2.73e-5)" "unprognostic (1.06e-1)" "unprognostic (1.48e-2)" "unprognostic (4.32e-2)" "unprognostic (4.60e-2)" 16.2 23.2 20.2 7.5 21.3 6.8 32.6 16.1 23.6 28.3 34.9 15.4 19.0 35.6 46.6 11.0 53.4 20.7 15.5 20.0 21.9 50.2 13.4 23.4 10.2 20.4 19.3 39.7 16.2 42.2 31.2 13.6 18.7 20.8 17.9 44.0 16.3 20.0 10.2 15.8 16.3 19.8 17.9 11.0 17.1 44.9 21.3 10.8 34.3 8.5 9.7 15.0 13.9 20.6 21.2 12.0 20.5 13.1 32.5 64.5 17.6 11.5 24.8 13.3 12.4 4.0 14.4 12.0 24.8 15.2 17.0 13.8 9.9 16.5 15.4 15.4 21.1 9.4 5.5 15.3 31.3 18.7 14.8 38.3 23.4 26.5 12.1 40.6 18.5 14.1 29.0 5.6 18.7 10.8 9.2 20.6 9.4 27.3 12.0 12.2 19.0 3.8 110.1 18.0 14.0 25.1 13.0 7.1 15.5 19.4 19.7 16.9 13.1 11.6 10.5 14.4 9.8 21.0 12.3 3.0 25.8 4.7 12.6 14.8 2.3 2.1 1.7 3.9 1.8 3.7 2.2 2.4 3.1 2.1 2.7 2.3 0.8 2.6 3.1 1.8 1.4 1.4 20.2 21.3 16.1 23.6 20.0 21.9 20.4 19.3 18.7 17.9 21.3 20.6 11.9 19.2 16.8 58.1 6.4 9.7 18.2 42.9 7.4 21.7 19.3 22.4 13.9 21.5 31.3 53.3 29.2 19.7 2.3 10.2 90.1 21.7 197.5 71.7 42.2 8.1 12.7 5.5 96.8 22.0 9.1 27.8 15.3 24.2 17.7 26.2 14.6 7.3 12.4 16.8 64.9 20.3 50.8 4.5 5.3 39.4 33.2 5.9 23.2 22.5 3.3 29.3 4.1 33.7 43.4 14.5 32.1 33.8 4.7 9.6 52.4 84.1 133.8 36.9 19.7 14.8 14.8 102.1 15.9 9.1 9.1 9.3 4.9 30.1 17.5 12.8 DYNLT2B "MGC33212, TCTEX1D2" ENSG00000213123 "Dynein light chain Tctex-type 2B" Q8WW35 3 196291219-196318299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Cardiomyocytes: 6.2;Cytotrophoblasts: 29.4;Extravillous trophoblasts: 9.9;Hofbauer cells: 16.8;Syncytiotrophoblasts: 6.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 21.9;dendritic cells: 16.2;T-cells: 25.1" "Cell line enhanced" "Detected in many" "T-47d: 101.7" HPA049555 Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA049555: AB_2680816" "unprognostic (1.16e-1)" "prognostic favorable (7.83e-4)" "unprognostic (5.34e-2)" "unprognostic (1.59e-2)" "unprognostic (1.47e-1)" "unprognostic (5.63e-2)" "unprognostic (2.65e-2)" "unprognostic (4.61e-1)" "unprognostic (9.98e-3)" "unprognostic (3.99e-2)" "unprognostic (3.44e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (6.23e-4)" "unprognostic (3.73e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (2.32e-1)" 5.0 7.9 15.2 4.5 15.7 5.1 6.5 14.6 18.6 8.7 15.0 9.1 3.4 7.1 7.9 13.0 36.2 5.1 6.3 15.2 16.0 16.9 2.3 7.0 8.8 15.2 16.8 7.3 5.1 7.9 13.8 3.1 17.0 7.0 4.2 15.0 5.2 3.9 3.0 8.4 4.0 3.7 15.7 4.3 5.0 30.9 16.6 14.7 10.1 1.5 6.0 6.7 9.4 15.0 33.1 23.9 45.3 28.0 11.1 22.3 5.4 13.8 9.3 16.8 18.8 7.9 45.0 21.0 23.0 12.1 7.0 33.7 17.8 14.5 16.3 18.4 13.3 8.6 22.3 3.4 12.7 6.4 0.9 12.1 38.2 14.7 17.1 30.5 10.2 44.0 13.3 10.8 32.6 79.0 28.9 29.4 29.6 36.6 41.5 37.3 7.7 8.7 38.9 13.4 50.9 39.7 29.2 17.2 28.0 18.7 101.7 18.3 19.2 15.0 5.8 6.1 18.0 16.9 38.0 48.8 45.0 11.4 25.8 0.0 3.1 1.4 11.7 1.2 7.1 21.9 13.9 9.0 8.8 13.7 9.1 9.4 1.8 4.6 0.8 16.2 25.1 6.3 15.2 15.7 14.6 18.6 15.2 16.0 15.2 16.8 17.0 15.7 16.6 15.0 5.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 29.4 2.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 9.9 3.3 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 6.2 0.5 0.0 0.0 0.0 DZIP1L "DZIP2, FLJ32844" ENSG00000158163 "DAZ interacting zinc finger protein 1 like" Q8IYY4 3 138061990-138115818 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 58.8;Respiratory ciliated cells: 74.0;Rod photoreceptor cells: 19.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030404 Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA030404: AB_10601548" "unprognostic (3.65e-2)" "unprognostic (8.37e-2)" "unprognostic (2.87e-2)" "unprognostic (3.71e-2)" "unprognostic (8.22e-2)" "unprognostic (6.50e-2)" "unprognostic (6.47e-4)" "unprognostic (1.54e-1)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (1.51e-2)" "unprognostic (2.35e-3)" "unprognostic (2.72e-1)" "unprognostic (9.98e-2)" "unprognostic (2.77e-2)" 4.9 1.4 1.7 2.2 2.2 8.8 4.7 5.9 2.1 8.6 15.3 5.0 2.2 8.1 1.9 2.5 12.8 5.7 3.3 2.2 2.3 5.6 1.0 5.7 0.9 5.7 7.4 7.0 6.3 2.7 2.1 2.0 4.2 4.1 1.5 4.6 2.1 3.3 1.0 7.8 2.1 4.6 4.3 2.6 7.2 4.1 2.6 0.4 3.6 0.9 0.7 6.1 5.3 2.2 5.4 3.1 6.1 5.1 3.8 5.1 1.4 8.6 5.1 5.0 6.3 2.0 0.4 0.0 4.3 8.0 7.0 1.7 4.5 2.0 2.4 1.2 4.4 2.4 7.5 0.3 3.1 1.8 4.0 5.4 2.0 5.5 2.6 5.1 2.8 1.4 1.8 0.0 6.9 0.3 0.0 0.8 7.4 0.0 1.1 0.0 7.1 0.0 2.3 8.5 2.1 4.8 8.9 0.0 4.3 3.4 2.3 3.7 2.2 12.3 5.6 6.0 4.5 0.0 0.0 0.1 4.9 2.6 4.8 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 2.2 5.9 2.1 2.2 2.3 5.7 7.4 4.2 4.3 2.6 2.2 1.4 3.2 2.0 4.2 0.0 3.6 0.6 1.9 7.4 8.6 0.2 2.5 2.9 7.2 7.7 1.8 8.4 0.1 0.0 0.0 5.9 3.8 17.4 58.8 8.5 2.6 0.0 1.3 4.0 1.2 0.1 6.5 7.1 1.1 0.0 7.4 0.0 0.0 1.4 3.3 2.9 0.0 2.0 3.2 2.6 1.8 6.2 3.5 0.0 3.7 0.6 2.7 0.0 2.5 0.2 5.9 0.0 4.1 0.0 0.4 0.0 0.8 74.0 19.4 0.0 7.2 9.8 0.6 2.3 1.7 4.3 0.0 0.5 1.7 0.0 0.1 EBF3 "COE3, DKFZp667B0210" ENSG00000108001 "EBF transcription factor 3" Q9H4W6 10 129835233-129973053 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.9;brain: 16.9" "Group enriched" "Detected in some" 5 "Adipocytes: 29.6;Endothelial cells: 13.1;Fibroblasts: 14.9;Skeletal myocytes: 33.5;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 16.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 12.5;HAP1: 13.6;LHCN-M2: 25.4;NB-4: 35.7;RH-30: 13.2;SCLC-21H: 28.7;THP-1: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (2.96e-1)" "unprognostic (3.78e-2)" "unprognostic (8.63e-3)" "unprognostic (2.60e-2)" "unprognostic (7.68e-2)" "unprognostic (4.50e-3)" "unprognostic (8.53e-6)" "unprognostic (2.93e-2)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.63e-1)" "unprognostic (4.16e-3)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (9.49e-2)" "unprognostic (4.58e-2)" 23.9 0.6 0.3 1.0 0.1 0.1 13.7 1.4 0.2 4.1 0.4 2.7 0.2 2.3 0.8 1.4 4.8 2.4 9.4 0.1 2.7 0.5 0.5 0.2 6.9 6.5 8.5 1.0 1.3 2.1 0.9 2.5 3.8 2.4 0.5 1.9 3.0 1.1 7.9 3.3 1.0 1.5 16.9 0.2 1.6 1.6 3.2 1.3 7.3 7.7 1.0 3.3 5.5 1.1 0.0 0.0 0.6 0.1 12.5 10.3 0.1 0.8 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.5 0.0 0.0 13.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 2.4 0.0 0.0 0.0 0.7 0.0 0.0 25.4 0.0 0.0 35.7 0.0 0.0 0.0 0.3 13.2 0.0 0.0 0.1 28.7 0.4 0.0 0.0 0.0 0.1 0.0 14.3 0.0 0.0 1.3 8.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.4 0.2 0.1 2.7 6.5 8.5 3.8 16.9 3.2 1.1 29.6 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 1.8 0.3 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 13.1 0.0 0.0 0.9 0.0 0.0 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.5 0.4 0.3 0.4 0.0 1.9 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.7 0.0 33.5 11.7 0.0 3.4 0.1 0.9 0.0 0.2 0.1 0.0 0.1 EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "EBP cholestenol delta-isomerase" Q15125 X 48521799-48528716 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease variant, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 328.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 674.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" 10.2 73.3 16.7 17.1 17.2 48.3 17.4 18.5 17.8 19.4 22.0 50.6 85.5 11.0 17.3 41.3 14.3 10.5 32.5 16.8 18.7 44.0 328.5 24.4 18.8 24.4 16.6 12.7 26.0 44.0 7.2 8.2 24.2 40.6 57.5 10.7 25.0 11.7 9.5 27.8 54.2 14.9 15.8 16.9 31.6 14.2 15.9 28.2 14.4 10.6 32.7 14.1 23.3 16.0 224.5 96.4 107.4 77.0 74.5 39.2 50.5 48.2 43.6 64.3 93.9 169.9 382.7 115.9 35.2 41.3 83.5 230.3 217.5 293.8 49.8 85.8 149.7 50.1 115.2 139.3 57.8 179.2 138.2 51.3 108.6 112.9 86.4 22.5 46.5 98.1 77.6 119.5 50.7 163.7 119.1 199.9 118.2 88.3 199.1 93.8 10.3 363.7 175.6 68.8 110.0 59.6 175.4 122.6 31.2 91.5 122.9 71.1 46.6 33.1 56.2 132.9 63.1 47.5 72.1 107.7 78.7 239.7 40.6 96.1 37.7 97.1 129.4 53.4 104.5 71.5 90.5 116.7 53.5 57.2 76.5 99.7 7.3 63.9 57.2 105.4 103.1 93.6 16.7 17.2 18.5 17.8 16.8 18.7 24.4 16.6 24.2 15.8 15.9 16.0 15.2 32.1 49.8 2.9 38.9 37.1 58.2 245.6 23.3 23.8 57.8 26.2 49.9 77.2 116.6 53.3 8.4 55.9 74.5 140.3 39.2 91.7 10.5 30.5 14.7 26.1 30.0 48.8 7.4 239.1 113.0 21.4 36.2 56.5 40.6 41.2 27.1 674.6 65.0 8.4 10.3 96.8 93.6 30.2 36.0 11.8 13.4 31.9 37.4 4.7 34.8 19.3 101.0 5.0 5.1 156.7 137.3 14.7 54.4 46.4 171.9 99.7 34.8 23.3 13.1 12.5 23.6 8.7 22.7 47.6 45.5 37.5 57.1 128.7 149.1 71.1 ECE1 ECE ENSG00000117298 "Endothelin converting enzyme 1" P42892 1 21217247-21345572 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 29.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 673.8;TIME: 588.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001490, HPA013616" Enhanced NA NA 1300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA001490: AB_1078718, HPA013616: AB_1847963" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (1.49e-2)" "unprognostic (1.46e-1)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "unprognostic (6.20e-2)" "unprognostic (1.92e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (7.70e-2)" "unprognostic (3.55e-2)" "unprognostic (9.10e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-2)" 87.3 123.2 26.5 47.7 29.4 48.1 79.4 23.0 30.1 61.4 12.6 71.0 30.1 42.4 10.0 26.7 46.9 36.8 70.9 21.3 33.7 38.1 54.0 72.1 35.7 34.4 25.7 71.0 91.8 125.0 47.4 66.5 30.4 53.1 34.7 14.7 33.6 25.1 19.8 34.3 46.1 42.3 21.2 48.5 43.3 22.7 28.1 21.1 51.4 33.2 34.9 58.8 43.8 27.5 93.0 60.1 77.9 38.3 111.0 116.4 44.1 135.4 236.8 72.9 66.6 44.1 275.8 34.0 323.6 138.8 157.7 38.4 32.6 64.9 63.5 83.0 27.2 48.7 89.9 34.8 144.3 7.1 11.8 61.6 74.3 112.6 55.8 199.2 673.8 27.6 10.0 17.7 62.9 19.4 14.6 11.4 23.2 26.3 46.5 17.5 45.0 49.2 114.0 17.0 26.4 63.1 134.3 79.2 57.4 42.5 55.9 20.2 588.7 160.7 77.9 73.3 79.9 26.4 49.0 39.1 332.6 16.5 196.6 0.2 8.4 3.3 2.9 10.0 4.2 6.1 6.1 4.6 0.7 4.1 4.0 2.7 29.8 1.5 7.8 2.8 8.6 7.2 26.5 29.4 23.0 30.1 21.3 33.7 34.4 25.7 30.4 21.2 28.1 27.5 164.0 19.2 7.5 46.4 25.1 20.3 19.7 81.6 18.8 5.0 71.3 44.7 18.9 10.0 54.7 23.9 0.0 6.0 12.4 105.8 5.9 25.8 1.5 19.6 35.2 106.1 25.2 20.2 19.2 56.7 35.0 51.8 20.9 51.8 18.4 35.4 97.1 36.0 3.3 0.0 14.8 13.0 57.0 9.6 14.3 4.2 43.5 17.3 7.2 31.9 25.5 50.4 8.2 13.6 22.5 100.4 106.5 55.3 29.4 34.9 45.7 7.5 24.2 4.4 39.5 72.7 47.5 1.3 5.9 8.5 16.1 10.5 17.9 80.6 21.6 40.8 ECEL1 "DINE, XCE" ENSG00000171551 "Endothelin converting enzyme like 1" O95672 2 232479827-232487834 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 106.9;ovary: 99.7;pituitary gland: 27.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 33.5;Muller glia cells: 100.3;Peritubular cells: 21.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 12.9" "Region enhanced" "Detected in many" "hypothalamus: 106.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AN3-CA: 44.1;HeLa: 21.8" "Region enhanced" "Detected in many" "hypothalamus: 70.7" "Low region specificity" "Detected in many" "HPA067560, HPA069756, HPA077424" Approved Supported Approved "Nucleoplasm,Nuclear membrane,Nucleoli" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "Nuclear membrane, Nucleoli" "HPA067560: , HPA069756: , HPA077424: " "unprognostic (1.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.39e-1)" "unprognostic (4.62e-3)" "unprognostic (2.80e-1)" "unprognostic (9.96e-4)" "unprognostic (7.56e-3)" "unprognostic (1.22e-1)" "unprognostic (9.89e-3)" "unprognostic (8.49e-2)" "unprognostic (1.54e-1)" "unprognostic (2.89e-1)" "unprognostic (1.24e-5)" "unprognostic (3.09e-2)" "unprognostic (3.68e-1)" "unprognostic (7.84e-2)" "unprognostic (5.45e-2)" 1.8 10.0 5.2 1.0 5.5 0.0 1.7 1.2 31.6 1.0 3.4 0.8 0.1 2.2 0.0 0.4 3.5 0.5 0.2 0.5 106.9 4.1 2.5 0.4 0.3 20.9 11.3 99.7 0.7 1.2 27.6 0.3 17.1 0.4 0.0 13.4 0.6 1.5 3.0 0.6 0.4 1.4 2.4 4.5 0.9 1.9 44.2 0.2 1.4 0.0 0.4 0.4 1.1 4.5 0.0 0.1 0.1 44.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.4 0.0 0.2 0.0 0.6 0.0 0.0 0.0 4.0 0.0 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 3.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 5.5 1.2 31.6 0.5 106.9 20.9 11.3 17.1 2.4 44.2 4.5 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 33.5 0.5 0.3 1.1 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.2 1.1 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.2 1.5 0.1 0.0 0.0 0.0 100.3 0.0 0.0 0.0 0.1 0.0 21.1 0.0 0.0 0.0 0.1 0.0 3.7 0.0 1.0 2.3 0.5 1.6 0.0 0.0 0.0 0.1 0.6 0.0 0.1 EDA "ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, ODT1, XHED, XLHED" ENSG00000158813 "Ectodysplasin A" Q92838 X 69616067-70039472 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 84.3;Oligodendrocyte precursor cells: 30.2;Oligodendrocytes: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;MAIT T-cell: 1.3" "Group enriched" "Detected in many" 5 "monocytes: 1.2;T-cells: 1.3" "Cell line enhanced" "Detected in many" "EFO-21: 5.2;Hep G2: 17.9;OE19: 5.1;RPMI-8226: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA037972, HPA037973" Supported "Vesicles,Lipid droplets" "Secreted - unknown location" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Lipid droplets" "HPA037972: AB_2675761, HPA037973: AB_2675762" "unprognostic (3.76e-2)" "unprognostic (8.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.59e-3)" "unprognostic (7.85e-2)" "unprognostic (1.25e-4)" "unprognostic (4.33e-4)" "unprognostic (5.03e-2)" "unprognostic (1.53e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-2)" "unprognostic (2.01e-1)" "prognostic favorable (1.04e-9)" "unprognostic (8.63e-4)" "unprognostic (7.64e-2)" "unprognostic (9.85e-2)" "unprognostic (2.79e-1)" 4.2 8.5 2.4 0.7 3.0 0.1 2.8 2.2 2.6 4.9 5.2 2.6 0.5 3.0 3.2 1.5 3.8 2.0 10.4 2.1 2.4 3.7 2.1 3.2 0.8 3.2 2.8 4.9 4.2 9.7 1.3 1.8 3.0 3.4 1.1 0.3 2.2 2.2 1.7 4.2 1.1 2.1 2.3 1.4 3.8 1.2 3.1 1.2 6.0 2.0 0.6 2.3 3.9 4.6 0.0 0.6 0.3 2.8 0.5 0.0 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.3 5.2 0.2 0.2 0.5 3.8 1.4 0.0 0.0 4.5 0.0 0.0 17.9 1.0 0.0 1.1 1.8 1.3 0.0 0.9 0.0 0.5 3.5 0.0 4.9 0.0 1.2 0.0 0.0 2.8 5.1 0.3 0.0 1.2 6.0 0.1 0.0 1.5 0.0 0.1 0.3 0.1 2.0 0.3 0.1 0.5 1.7 2.2 2.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.0 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.8 0.0 0.0 0.1 2.4 3.0 2.2 2.6 2.1 2.4 3.2 2.8 3.0 2.3 3.1 4.6 3.3 3.2 0.5 21.2 0.3 3.8 2.6 2.0 6.8 0.2 0.9 1.5 12.1 0.0 1.1 5.5 0.0 0.2 0.1 1.0 0.0 1.3 21.3 4.6 1.2 2.2 1.8 0.0 17.9 1.3 0.2 6.0 5.6 12.2 0.0 0.5 11.0 1.2 4.1 0.0 9.6 0.6 0.0 4.8 1.2 9.2 4.7 2.8 1.8 84.3 0.1 1.3 0.0 30.2 45.9 1.1 0.1 2.2 0.2 2.3 0.4 3.1 1.3 0.1 6.6 10.7 5.4 1.7 3.5 3.2 4.1 0.0 2.1 0.4 0.9 1.5 EDAR "DL, ED1R, ED3, ED5, EDA1R, EDA3" ENSG00000135960 "Ectodysplasin A receptor" Q9UNE0 2 108894471-108989372 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 3.6" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 3.4;Macrophages: 1.1;Squamous epithelial cells: 5.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 4.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "naive CD4 T-cell: 7.5;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 75 "T-cells: 7.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.7;HaCaT: 10.2;OE19: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA042292 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "HPA042292: AB_10794648" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (2.22e-2)" "unprognostic (1.24e-2)" "unprognostic (4.68e-2)" "unprognostic (1.21e-2)" "unprognostic (2.30e-1)" "unprognostic (2.53e-2)" "unprognostic (3.70e-1)" "unprognostic (1.31e-1)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (8.83e-7)" "unprognostic (9.21e-2)" "unprognostic (5.61e-2)" "unprognostic (2.29e-1)" "unprognostic (5.03e-3)" 0.0 0.0 0.0 0.9 0.0 0.3 0.2 0.0 0.2 0.6 0.0 1.3 1.1 0.5 0.2 3.6 0.2 0.9 0.0 0.1 0.0 0.6 0.9 0.2 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.7 1.9 0.0 0.6 0.1 0.0 1.4 1.0 0.0 0.0 0.2 0.9 0.1 0.1 1.2 0.0 0.0 1.2 1.5 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.7 0.0 0.4 0.0 0.0 10.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 7.5 3.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.4 0.0 0.1 0.6 0.5 0.0 0.8 0.0 0.0 0.2 0.1 0.1 0.0 0.7 0.0 0.3 0.3 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 0.8 0.0 0.3 0.8 EDARADD ENSG00000186197 "EDAR associated death domain" Q8WWZ3 1 236348257-236502915 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 8.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 26.7;granulocytes: 22.7;Syncytiotrophoblasts: 22.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "basophil: 49.5" "Lineage enriched" "Detected in many" 8 "granulocytes: 49.5" "Cell line enhanced" "Detected in some" "BEWO: 15.9;HDLM-2: 13.2;HMC-1: 52.7;RT4: 45.3;T-47d: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA018836 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA018836: AB_1847984" "unprognostic (3.74e-1)" "unprognostic (3.10e-2)" "unprognostic (2.92e-1)" "unprognostic (2.12e-2)" "unprognostic (2.06e-3)" "unprognostic (3.12e-3)" "unprognostic (9.94e-2)" "unprognostic (2.96e-2)" "unprognostic (2.62e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (2.57e-2)" "unprognostic (5.72e-2)" "unprognostic (3.00e-1)" "unprognostic (2.47e-1)" "unprognostic (1.90e-2)" "unprognostic (9.62e-3)" 0.4 0.1 0.2 0.4 0.1 0.4 4.8 0.1 0.1 0.7 0.0 0.3 0.4 0.4 5.2 3.3 1.2 0.8 0.9 0.1 0.1 1.1 0.3 0.7 1.2 0.2 0.2 0.4 3.8 0.1 0.1 4.9 0.1 3.6 0.3 0.0 1.4 6.1 0.0 5.8 0.3 0.1 0.1 1.2 6.3 3.4 0.2 2.3 6.4 0.0 2.6 8.7 1.0 0.1 0.0 3.8 0.3 0.0 0.0 0.0 15.9 0.0 0.0 1.3 0.8 1.0 0.0 0.0 0.0 0.2 4.3 8.8 6.5 9.6 1.2 13.2 7.6 0.1 0.1 1.4 0.0 0.4 52.7 0.0 2.7 0.9 0.8 0.0 0.0 1.8 0.4 0.0 0.0 0.4 0.3 0.0 3.9 0.0 0.0 3.4 0.1 0.0 0.0 45.3 0.4 0.3 0.0 1.2 0.2 0.3 12.6 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 49.5 0.3 0.1 3.1 0.4 4.1 0.1 4.7 6.1 0.5 0.2 0.4 3.2 0.3 5.3 0.2 0.1 5.1 2.1 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.3 0.0 1.3 0.0 0.4 6.9 7.3 16.3 13.1 0.0 7.1 7.4 4.1 5.7 8.4 0.0 0.0 26.7 3.0 0.1 3.9 1.7 10.6 0.2 1.2 1.2 0.0 2.5 0.5 0.9 14.2 1.1 5.1 0.4 22.7 2.8 5.0 0.5 3.4 0.0 0.6 0.1 8.2 1.5 8.9 9.3 0.3 0.6 12.4 1.0 3.7 0.6 0.0 1.0 0.4 0.6 0.0 0.4 1.8 4.2 0.1 0.4 3.2 0.1 0.0 1.4 6.1 13.4 3.7 6.5 5.3 22.6 6.2 0.3 0.0 5.3 EDN1 ET1 ENSG00000078401 "Endothelin 1" P05305 6 12290361-12297194 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 44.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 749.7;Ductal cells: 316.3;Glandular and luminal cells: 289.7;Pancreatic endocrine cells: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 6 "monocytes: 4.9" "Cell line enhanced" "Detected in many" "EFO-21: 660.4;HUVEC TERT2: 446.8;T-47d: 137.5;TIME: 334.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031976, CAB032500, CAB037291" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted to blood" NA Yes 9740 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Golgi apparatus" Nucleoplasm "CAB032500: AB_2096241, CAB037291: AB_259277, HPA031976: AB_10602489" "unprognostic (1.51e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "unprognostic (9.72e-2)" "unprognostic (3.40e-1)" "unprognostic (1.91e-1)" "unprognostic (6.24e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (8.92e-2)" "unprognostic (4.19e-2)" "unprognostic (3.17e-1)" "unprognostic (8.02e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (3.47e-1)" 44.6 1.8 14.7 7.3 13.8 4.7 23.6 13.6 18.2 6.2 9.7 10.6 10.4 7.0 6.3 12.1 9.4 13.5 7.8 12.6 12.2 7.7 3.1 36.6 5.6 15.1 13.6 2.6 9.6 1.4 1.1 18.5 15.2 5.5 14.5 1.0 12.1 8.9 7.6 11.8 9.8 11.3 13.1 12.3 10.4 4.7 15.7 1.7 3.4 6.4 2.4 9.9 5.9 14.2 10.3 57.6 1.1 0.1 0.3 0.2 0.2 18.2 16.0 15.0 12.4 74.6 8.6 0.0 660.4 7.2 9.2 5.4 0.0 10.6 11.0 0.8 0.0 0.0 2.1 2.3 0.8 0.0 0.0 0.4 6.2 3.0 2.1 4.7 446.8 0.0 0.0 0.0 56.8 1.6 0.2 0.3 0.6 10.4 0.7 0.2 5.1 0.1 35.3 9.4 0.6 0.0 1.8 53.1 0.1 117.2 137.5 0.8 334.3 37.1 30.1 0.7 23.5 0.3 0.4 1.3 0.3 0.0 1.6 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 4.9 0.1 0.0 0.0 14.7 13.8 13.6 18.2 12.6 12.2 15.1 13.6 15.2 13.1 15.7 14.2 190.7 173.1 23.8 2.9 0.8 189.9 749.7 99.9 151.4 0.2 68.7 26.8 2.2 8.6 110.6 38.6 0.0 1.8 0.8 189.7 3.9 316.3 13.3 187.2 16.3 236.8 15.6 2.7 3.6 218.9 0.4 9.0 22.4 289.7 1.3 0.8 169.2 1.8 1.8 1.7 3.0 43.8 12.2 5.0 6.7 19.8 5.6 5.3 8.8 6.5 10.9 0.3 0.0 3.5 0.6 268.5 145.7 0.4 0.4 185.8 119.6 8.3 27.4 0.4 6.6 1.8 21.8 1.0 0.6 53.7 64.5 0.8 9.7 0.1 196.6 141.8 EDN3 ET3 ENSG00000124205 "Endothelin 3" P14138 20 59300443-59325992 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Deafness, Disease variant, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 53.1;salivary gland: 68.3;vagina: 106.5" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 99.6;Distal enterocytes: 86.6;Paneth cells: 72.4;Proximal enterocytes: 93.0;Skeletal myocytes: 110.0;Squamous epithelial cells: 69.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 30900 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 37: Intestine - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (4.64e-3)" "unprognostic (7.87e-2)" "unprognostic (7.49e-2)" "unprognostic (2.88e-3)" "prognostic favorable (1.73e-4)" "unprognostic (1.58e-1)" "unprognostic (1.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (4.01e-2)" "unprognostic (4.08e-2)" "unprognostic (4.48e-1)" "unprognostic (6.11e-2)" "unprognostic (1.55e-1)" "unprognostic (6.40e-2)" 0.1 2.3 4.9 2.0 5.1 0.0 7.8 4.8 5.9 53.1 3.3 20.2 42.0 5.2 6.1 20.6 0.2 0.4 0.1 4.9 4.5 0.2 0.0 0.4 0.2 5.5 7.3 1.3 8.8 0.3 44.7 0.2 8.6 5.6 18.8 2.0 68.3 0.5 1.5 1.9 40.6 3.0 5.0 7.9 1.7 1.2 11.2 3.2 24.2 2.4 0.1 0.1 106.5 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.9 5.1 4.8 5.9 4.9 4.5 5.5 7.3 8.6 5.0 11.2 3.9 0.1 9.6 0.5 0.0 0.0 0.4 5.1 0.0 99.6 0.1 1.7 21.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 86.6 0.0 0.3 0.0 1.6 11.2 0.4 1.2 0.0 0.8 0.0 0.3 2.6 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.6 0.0 0.0 0.4 0.0 0.0 0.5 0.0 20.6 0.0 0.4 0.0 0.0 0.0 0.2 72.4 1.9 1.2 0.2 93.0 0.0 0.0 0.4 0.0 110.0 0.4 0.1 0.8 69.2 0.3 0.0 0.3 0.1 15.9 0.3 EDNRA "ET-A, ETA-R, hET-AR" ENSG00000151617 "Endothelin receptor type A" P25101 4 147480917-147544954 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 113.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 117.1;Leydig cells: 43.8;Peritubular cells: 68.1;Sertoli cells: 52.6;Smooth muscle cells: 108.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 9.4;ASC TERT1: 18.2;HHSteC: 9.3;LHCN-M2: 22.7;SH-SY5Y: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013774, CAB018957" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB018957: AB_2039838, HPA013774: AB_1847994" "unprognostic (3.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.20e-2)" "unprognostic (7.20e-2)" "unprognostic (2.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.34e-3)" "unprognostic (2.88e-1)" "prognostic unfavorable (1.50e-7)" "prognostic unfavorable (3.93e-4)" "unprognostic (6.20e-3)" "unprognostic (3.11e-2)" "unprognostic (2.53e-3)" 14.0 5.5 2.1 3.3 2.8 0.0 8.3 2.7 4.2 57.0 2.1 3.2 3.4 44.7 23.3 4.4 18.4 12.7 26.0 2.2 2.2 4.2 3.1 22.7 3.8 2.9 3.1 37.5 1.1 3.4 2.8 12.1 2.9 30.7 3.4 0.3 6.4 113.9 4.0 4.6 2.9 45.1 2.5 8.4 5.4 6.2 2.9 4.9 6.8 5.5 2.6 11.8 24.0 3.0 0.0 1.2 5.2 0.0 9.4 18.2 0.0 2.9 3.8 0.4 0.1 0.2 0.0 0.0 0.0 0.9 0.6 0.0 0.4 0.7 0.2 0.0 1.9 0.0 2.8 0.0 9.3 0.0 0.0 6.9 0.6 0.5 0.0 3.4 0.0 0.0 0.0 1.4 22.7 0.3 0.0 0.1 1.5 0.0 1.1 0.0 0.9 0.1 1.3 1.0 0.0 16.3 0.0 0.0 0.0 3.4 0.0 0.0 0.0 3.6 0.7 0.0 0.0 1.3 0.4 0.0 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.8 2.7 4.2 2.2 2.2 2.9 3.1 2.9 2.5 2.9 3.0 7.7 3.2 5.3 1.0 0.0 3.1 0.8 1.7 27.3 0.1 0.8 5.2 24.9 0.0 4.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 2.9 3.4 117.1 8.0 0.0 0.0 5.3 0.0 0.1 15.9 0.0 2.7 0.0 14.3 0.0 0.0 0.6 0.0 22.5 0.0 0.0 0.0 3.9 3.5 43.8 0.8 3.6 9.4 0.0 0.1 0.0 2.0 1.0 0.2 0.0 68.1 0.0 1.4 0.0 0.5 0.0 0.5 52.6 0.6 108.6 0.7 0.7 7.1 2.7 0.1 0.9 0.3 0.0 0.4 EDNRB "ETB, HSCR, HSCR2" ENSG00000136160 "Endothelin receptor type B" P24530 13 77895481-77975529 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 127.8" "Cell type enhanced" "Detected in many" "Adipocytes: 120.5;Astrocytes: 126.3;Hepatic stellate cells: 112.5;Melanocytes: 110.3;Muller glia cells: 116.2;Sertoli cells: 216.9;Skeletal myocytes: 81.3;Smooth muscle cells: 102.1" "Cancer enhanced" "Detected in all" "melanoma: 127.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 68.0;ASC diff: 50.5;SK-MEL-30: 66.0;U-266/70: 40.7;WM-115: 131.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017842, HPA027546" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "CAB017842: , HPA027546: AB_2672327" "unprognostic (7.75e-2)" "unprognostic (6.73e-2)" "unprognostic (1.41e-3)" "unprognostic (2.59e-2)" "unprognostic (8.37e-2)" "unprognostic (2.45e-3)" "unprognostic (4.17e-3)" "unprognostic (5.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (3.40e-2)" "unprognostic (3.01e-2)" "prognostic favorable (7.20e-5)" "unprognostic (1.59e-2)" "unprognostic (3.86e-2)" "unprognostic (4.58e-2)" "unprognostic (6.77e-3)" 58.8 41.2 34.7 19.5 50.8 0.9 39.8 44.6 26.1 18.7 6.7 13.0 20.0 13.1 3.7 8.2 14.1 14.9 28.1 27.5 51.6 33.0 50.9 51.2 10.4 76.2 66.0 4.7 11.4 15.3 9.6 127.8 47.9 25.3 13.2 17.9 27.0 6.9 11.3 12.5 21.9 12.9 97.2 16.8 10.6 2.3 64.9 4.0 31.8 18.8 4.7 23.6 15.5 78.7 5.7 0.0 68.0 0.0 50.5 2.0 1.0 0.0 0.1 0.0 0.0 25.9 0.0 0.0 2.6 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 3.5 0.0 0.2 13.2 0.0 0.0 0.0 0.1 0.6 0.0 0.2 0.2 1.7 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.5 0.1 0.0 66.0 8.9 0.0 0.3 0.3 0.6 0.1 0.0 0.4 40.7 24.9 0.1 1.2 0.0 131.8 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 34.7 50.8 44.6 26.1 27.5 51.6 76.2 66.0 47.9 97.2 64.9 78.7 120.5 12.8 51.0 126.3 0.2 14.8 1.0 0.0 1.2 5.8 1.2 2.8 10.8 0.0 2.5 0.0 6.2 14.7 0.3 0.1 0.0 0.0 2.9 2.9 20.7 73.3 0.0 0.0 1.3 0.0 13.9 51.1 1.1 35.9 6.3 2.1 112.5 1.1 13.4 0.0 1.6 0.0 0.0 18.7 10.6 2.2 79.9 5.2 110.3 6.5 0.1 116.2 0.0 48.2 0.9 0.1 0.0 2.6 0.1 2.6 0.0 0.1 1.5 4.4 216.9 81.3 102.1 0.4 2.1 0.2 7.2 5.7 1.6 2.5 0.0 1.5 EED "HEED, WAIT-1" ENSG00000074266 "Embryonic ectoderm development" O75530 11 86244753-86278813 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012211, HPA060089, HPA061140" Supported Supported Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 59: Non-specific - Transcription" Nucleoplasm "CAB012211: AB_2262066, HPA060089: AB_2684201, HPA061140: AB_2684437" "unprognostic (7.46e-2)" "unprognostic (4.40e-2)" "unprognostic (1.65e-1)" "unprognostic (1.02e-2)" "unprognostic (1.33e-1)" "unprognostic (3.13e-2)" "prognostic unfavorable (1.80e-5)" "unprognostic (2.90e-1)" "unprognostic (1.32e-2)" "unprognostic (2.39e-1)" "unprognostic (2.31e-1)" "unprognostic (9.19e-3)" "prognostic unfavorable (1.36e-7)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" "unprognostic (1.33e-2)" "prognostic favorable (2.27e-5)" 9.3 9.0 13.2 16.3 13.1 9.2 11.4 15.0 15.8 13.8 13.1 12.1 12.1 11.5 15.2 12.7 10.6 9.3 8.9 12.8 13.5 11.5 11.9 8.5 28.8 12.9 12.8 12.1 10.5 9.1 9.4 14.5 13.1 11.7 11.9 16.4 10.3 10.6 10.5 12.1 11.6 10.2 12.9 14.4 10.9 10.3 13.6 17.8 10.7 11.1 32.1 13.0 12.1 13.9 34.2 37.8 40.9 16.8 22.6 20.2 47.0 49.2 22.6 46.3 46.8 121.0 64.4 79.8 50.6 15.8 44.2 41.4 48.7 26.8 43.2 79.7 22.7 51.4 38.7 36.3 19.8 54.2 33.4 12.4 18.0 46.8 20.1 17.5 20.9 34.7 58.8 16.2 39.0 55.2 51.5 55.4 30.4 107.8 18.4 56.2 49.1 38.8 29.1 55.4 27.5 22.4 63.5 29.6 14.5 29.1 49.2 22.6 19.0 48.1 44.1 70.0 43.2 9.2 32.1 63.9 13.7 46.6 36.8 31.0 9.1 15.0 25.4 15.3 22.1 45.0 33.2 32.0 13.9 47.3 26.4 29.6 3.9 19.3 16.8 9.2 58.6 19.1 13.2 13.1 15.0 15.8 12.8 13.5 12.9 12.8 13.1 12.9 13.6 13.9 15.4 6.4 9.3 28.1 32.7 25.6 11.6 27.5 25.0 26.4 13.3 11.8 9.5 11.5 15.4 7.3 18.8 45.2 31.0 16.1 19.6 14.5 7.7 17.6 17.1 16.6 7.2 15.8 35.0 10.2 36.8 14.8 16.3 15.5 15.9 15.0 13.2 11.4 16.9 32.0 45.6 12.8 12.2 14.5 32.5 3.6 22.7 15.2 19.6 37.5 30.4 11.5 25.7 31.2 38.9 11.9 11.1 17.3 17.6 11.9 11.7 8.6 21.3 18.3 6.6 14.3 24.5 18.7 20.0 16.9 16.8 24.9 31.6 17.5 15.0 20.9 EFEMP2 "FBLN4, UPH1" ENSG00000172638 "EGF containing fibulin extracellular matrix protein 2" O95967 11 65866441-65873592 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 122.8;Leydig cells: 93.5;Muller glia cells: 84.8;Peritubular cells: 107.2;Smooth muscle cells: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 125.8;BJ hTERT+: 159.7;fHDF/TERT166: 232.6;HSkMC: 155.3;hTERT-RPE1: 159.1;LHCN-M2: 134.5;U-138 MG: 114.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023270 Approved "Secreted to extracellular matrix" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA023270: AB_1848019" "unprognostic (3.13e-1)" "unprognostic (2.15e-3)" "unprognostic (3.23e-2)" "unprognostic (5.11e-2)" "unprognostic (8.57e-3)" "unprognostic (1.50e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.89e-2)" "unprognostic (9.12e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (8.33e-3)" "unprognostic (6.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.58e-2)" 38.4 18.0 19.8 13.8 21.1 2.8 29.5 18.8 26.7 46.6 22.1 39.6 9.3 55.2 8.3 12.8 35.8 33.5 61.6 19.1 20.4 26.8 7.0 32.1 9.1 24.9 20.0 47.0 19.9 26.8 15.2 22.4 21.4 31.1 6.5 5.9 17.4 35.2 21.2 14.9 16.2 32.3 20.3 16.1 20.6 8.2 21.4 5.6 39.1 22.0 5.0 33.1 30.7 19.1 0.5 0.2 2.1 47.3 54.3 108.0 0.8 125.8 159.7 48.1 44.8 0.0 4.3 0.7 9.3 232.6 0.7 0.9 0.0 1.3 12.1 5.4 0.1 1.1 3.2 8.0 89.1 0.0 0.4 155.3 0.4 18.9 1.0 159.1 28.5 1.0 0.3 8.0 134.5 0.4 0.2 20.7 1.6 0.2 0.6 0.4 0.3 3.2 1.6 0.6 0.7 14.1 0.2 1.3 1.5 6.6 1.5 10.0 64.6 114.2 24.7 52.6 0.6 10.9 0.7 0.3 42.6 0.8 19.7 0.0 0.1 0.5 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.7 0.0 0.0 0.0 0.2 19.8 21.1 18.8 26.7 19.1 20.4 24.9 20.0 21.4 20.3 21.4 19.1 30.8 35.3 7.4 29.0 1.5 13.5 38.9 33.9 8.6 7.7 10.2 27.6 46.0 15.7 11.4 18.4 0.0 2.4 2.3 0.3 7.9 28.7 15.6 3.4 57.1 27.9 0.0 0.4 1.1 0.2 3.9 122.8 2.6 4.1 0.0 74.3 42.8 1.8 9.8 6.7 2.9 0.3 4.1 3.5 19.1 33.3 93.5 3.0 24.9 9.4 0.7 84.8 2.1 9.5 1.6 2.6 0.1 107.2 1.4 30.1 0.2 21.2 9.0 4.8 39.5 41.1 113.2 35.9 3.3 1.1 10.1 5.9 2.4 78.5 0.3 14.2 EFNB1 "CFNS, Elk-L, EPLG2, LERK2" ENSG00000090776 "Ephrin B1" P98172 X 68829021-68842160 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 117.3;Granulosa cells: 134.5;Hepatic stellate cells: 143.5;Suprabasal keratinocytes: 120.5;Theca cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 97.0;hTCEpi: 74.1;PC-3: 70.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031489, HPA067188" Uncertain Supported "Plasma membrane" NA NA 1300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "CAB031489: AB_631414, HPA067188: AB_2685799" "unprognostic (2.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.04e-1)" "unprognostic (2.48e-2)" "unprognostic (8.05e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (1.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.76e-2)" "unprognostic (8.03e-2)" "unprognostic (1.72e-3)" "unprognostic (1.86e-2)" 47.0 23.7 9.3 8.2 9.5 2.3 41.2 8.7 11.8 27.1 8.7 27.6 19.1 19.4 10.7 32.0 19.6 18.3 32.5 9.1 8.9 44.0 11.6 41.6 4.3 9.4 9.1 14.3 7.6 16.5 10.3 25.4 8.9 19.8 13.2 1.2 11.2 16.2 9.1 52.5 20.6 8.8 9.6 26.1 18.1 6.3 9.7 5.6 19.6 9.5 4.8 25.9 27.9 9.3 10.4 5.3 41.9 15.6 21.7 13.4 21.9 8.7 9.5 3.8 2.8 4.8 19.0 2.5 56.7 3.3 5.0 54.3 40.0 97.0 2.1 4.3 10.2 2.6 2.3 8.5 20.0 1.9 21.3 25.0 74.1 9.4 42.4 3.4 29.3 5.3 2.8 0.2 3.3 8.5 4.2 2.0 29.0 63.5 70.9 18.6 4.4 16.6 15.9 36.1 15.6 7.5 6.7 2.0 2.6 31.7 1.6 3.6 49.7 7.2 8.9 19.6 3.3 0.1 2.3 2.5 3.6 11.3 4.7 0.0 0.6 0.3 0.4 1.7 0.3 0.3 0.4 0.4 3.5 0.2 0.3 0.2 0.1 0.7 1.1 0.5 0.2 0.5 9.3 9.5 8.7 11.8 9.1 8.9 9.4 9.1 8.9 9.6 9.7 9.3 81.1 3.2 1.1 2.6 3.2 117.3 66.2 60.7 93.4 3.3 3.6 11.2 8.2 20.0 12.8 22.0 0.0 11.4 5.9 59.4 0.0 16.4 0.4 2.6 7.6 42.4 8.4 2.7 1.0 15.6 75.9 20.5 21.4 4.5 4.5 134.5 143.5 4.8 12.4 1.7 1.0 27.6 8.2 9.1 23.8 1.3 27.4 8.6 21.4 2.8 5.9 12.5 2.1 0.5 0.6 46.3 52.6 8.2 2.3 40.2 28.6 5.7 2.8 1.3 13.1 8.7 12.5 2.0 3.8 76.2 120.5 11.2 4.7 116.2 29.8 93.6 EFTUD2 "SNRNP116, Snrp116, Snu114, U5-116KD" ENSG00000108883 "Elongation factor Tu GTP binding domain containing 2" Q15029 17 44849948-44899445 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022021 Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA 94000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Vesicles, Cytosol" "HPA022021: AB_1848032" "unprognostic (4.28e-2)" "unprognostic (4.12e-2)" "unprognostic (1.98e-3)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (4.98e-2)" "prognostic unfavorable (2.71e-6)" "unprognostic (6.94e-2)" "unprognostic (4.52e-1)" "unprognostic (2.37e-1)" "unprognostic (4.11e-3)" "unprognostic (5.19e-2)" "unprognostic (5.48e-3)" "unprognostic (1.62e-2)" "unprognostic (5.30e-2)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" 23.6 30.7 26.7 31.3 27.2 37.4 22.4 24.6 28.0 17.6 27.9 26.5 21.6 19.4 18.8 33.1 25.0 16.3 35.3 28.0 26.3 26.1 26.2 22.6 35.5 25.6 26.1 17.6 24.0 27.9 13.2 28.6 26.4 17.8 28.8 15.5 22.5 18.6 65.8 28.5 22.8 23.5 25.1 29.8 22.5 27.5 27.3 41.0 21.2 38.3 46.5 28.8 20.3 26.6 88.7 173.6 82.8 134.9 61.9 60.9 97.1 68.7 91.4 169.6 146.0 134.6 73.9 152.1 79.0 87.1 130.3 98.6 181.5 120.2 196.2 153.9 150.8 150.9 100.9 144.5 68.2 179.9 107.5 66.5 67.4 157.2 85.0 65.2 149.1 134.8 189.6 57.8 98.0 88.2 182.3 118.6 85.7 206.8 143.1 126.1 168.1 132.0 97.0 97.8 135.7 81.1 67.7 49.5 73.9 120.6 131.6 112.2 91.4 126.5 97.4 77.7 176.3 60.2 81.4 150.0 101.6 98.4 132.0 42.7 84.3 85.9 37.2 81.6 41.7 32.3 32.9 36.1 82.8 31.3 28.8 32.2 13.0 44.2 85.0 35.5 35.2 70.7 26.7 27.2 24.6 28.0 28.0 26.3 25.6 26.1 26.4 25.1 27.3 26.6 11.3 0.0 14.0 11.1 18.1 11.7 12.2 15.1 13.6 14.7 14.1 11.8 21.1 22.8 15.3 18.4 33.3 34.5 14.0 15.6 3.9 29.4 12.5 17.8 17.9 21.4 10.8 24.8 17.5 26.7 30.9 14.0 18.3 18.8 19.7 22.6 21.8 22.4 38.5 26.9 17.2 13.4 16.2 30.1 17.5 6.5 12.8 26.2 5.4 12.2 46.7 12.0 21.6 6.0 15.5 27.7 12.0 9.1 20.3 14.5 15.9 13.2 17.4 18.0 19.7 14.8 14.8 28.2 43.3 16.0 14.6 27.2 16.3 21.4 22.2 12.5 EHMT1 "bA188C12.1, EHMT1-IT1, Eu-HMTase1, FLJ12879, FLJ40292, KIAA1876, KMT1D" ENSG00000181090 "Euchromatic histone lysine methyltransferase 1" Q9H9B1 9 137618992-137870016 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 167.0;Plasma cells: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060022, HPA074729" Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Nuclear bodies" "HPA060022: AB_2684190, HPA074729: " "unprognostic (1.18e-1)" "unprognostic (1.64e-1)" "unprognostic (1.19e-2)" "prognostic favorable (6.56e-4)" "unprognostic (1.03e-1)" "prognostic favorable (8.91e-4)" "unprognostic (5.87e-2)" "unprognostic (1.74e-2)" "unprognostic (4.18e-3)" "unprognostic (2.34e-1)" "unprognostic (2.26e-2)" "unprognostic (7.55e-3)" "unprognostic (2.01e-2)" "unprognostic (6.58e-3)" "unprognostic (4.24e-1)" "unprognostic (7.12e-3)" "unprognostic (7.75e-2)" 17.7 18.3 11.0 22.3 12.0 30.5 18.2 16.0 12.3 17.0 13.8 19.3 18.8 21.5 9.7 19.1 18.1 14.0 13.5 8.6 8.3 11.0 14.4 15.8 29.6 10.7 10.2 19.9 14.9 13.8 12.9 15.0 11.1 16.2 13.1 13.7 18.4 13.9 31.4 19.3 19.6 15.1 4.4 25.9 18.2 40.5 12.7 22.9 19.6 15.0 21.2 18.3 16.2 19.9 26.7 52.3 57.4 53.2 23.9 24.6 48.1 34.5 21.4 24.7 20.2 34.7 32.5 81.6 32.7 26.0 29.9 56.2 34.8 37.8 19.2 45.3 24.7 34.4 54.2 22.4 20.9 52.9 39.5 22.6 25.9 29.9 28.9 18.1 41.3 30.1 52.6 27.5 17.9 61.9 62.5 26.3 56.0 42.1 34.8 79.3 49.5 47.2 20.7 47.7 50.6 41.1 65.4 45.4 15.3 40.6 51.1 42.0 39.0 28.9 29.5 44.8 33.2 17.2 52.0 67.0 21.3 27.6 32.0 19.5 16.2 21.2 18.0 14.3 11.3 16.4 15.6 15.6 12.9 23.0 14.9 13.5 28.8 17.3 15.6 23.3 14.2 9.7 11.0 12.0 16.0 12.3 8.6 8.3 10.7 10.2 11.1 4.4 12.7 19.9 34.3 19.2 19.2 130.6 64.9 17.5 23.4 26.9 32.5 39.7 30.5 26.7 31.5 25.8 24.7 22.0 52.1 23.8 36.9 24.4 3.9 24.1 86.8 29.3 44.8 29.9 28.1 31.7 74.4 21.0 21.8 27.6 45.3 40.6 18.9 55.8 18.9 41.7 19.7 50.5 76.4 22.2 10.2 25.8 18.1 167.0 35.8 26.9 12.4 71.2 31.2 19.7 51.5 64.3 104.0 25.4 30.3 37.6 170.6 34.9 20.7 14.3 22.6 46.8 13.1 34.7 28.5 80.4 51.9 35.3 20.2 26.5 38.9 81.3 23.8 28.8 EIF2S3 "EIF2, EIF2G, EIF2gamma" ENSG00000130741 "Eukaryotic translation initiation factor 2 subunit gamma" P41091 X 24054946-24078810 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Hydrolase, Initiation factor" "Disease variant, Epilepsy, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" CAB012471 Approved NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "CAB012471: AB_873547" "unprognostic (1.40e-1)" "unprognostic (1.38e-1)" "unprognostic (1.86e-1)" "unprognostic (5.27e-2)" "unprognostic (8.45e-2)" "unprognostic (1.46e-3)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.47e-1)" "unprognostic (1.68e-1)" "unprognostic (6.66e-3)" "unprognostic (6.94e-3)" "unprognostic (1.09e-1)" "prognostic unfavorable (5.44e-6)" "unprognostic (4.88e-3)" "unprognostic (2.11e-1)" "unprognostic (1.02e-1)" "unprognostic (2.51e-1)" 65.5 51.8 31.9 71.8 33.5 76.2 82.9 35.7 35.4 78.0 42.5 67.2 66.4 83.8 45.0 62.5 79.9 53.3 57.1 31.4 33.0 69.6 74.6 50.7 113.3 35.9 32.2 131.3 94.8 49.6 30.1 46.4 35.7 51.7 66.3 46.9 69.7 41.7 66.7 71.8 53.0 74.3 35.8 72.1 66.7 18.6 34.8 97.6 69.9 51.8 111.6 66.4 65.6 41.4 261.0 256.0 110.3 182.7 113.5 235.5 73.2 142.3 127.4 114.8 130.6 290.8 174.3 449.5 141.0 104.9 251.9 165.1 344.7 271.3 140.8 147.8 203.7 177.2 467.8 164.3 126.2 304.0 219.4 206.9 169.2 129.6 269.7 152.9 166.2 176.0 275.4 176.0 127.7 124.8 170.6 278.8 268.2 118.1 146.5 169.5 215.2 271.4 155.4 241.5 60.2 130.8 232.3 224.7 239.8 205.5 289.6 205.1 140.2 97.1 66.7 177.3 125.3 156.6 322.4 240.9 120.9 193.1 113.7 64.4 141.1 27.9 84.9 151.9 147.8 156.0 148.8 113.9 123.9 120.6 187.5 156.6 51.2 106.3 132.6 97.4 124.2 127.2 31.9 33.5 35.7 35.4 31.4 33.0 35.9 32.2 35.7 35.8 34.8 41.4 76.5 44.8 54.5 48.0 187.6 126.6 98.0 51.8 145.1 25.3 128.4 91.2 49.1 74.4 49.0 40.5 25.0 59.6 127.5 35.2 111.6 67.9 0.5 67.3 109.4 67.5 44.9 92.5 19.0 57.6 122.1 72.3 78.5 90.9 100.8 84.6 84.3 58.8 89.1 20.2 20.1 65.0 32.6 138.9 91.9 3.5 67.7 109.7 55.2 36.5 134.5 30.4 78.2 23.6 31.4 59.5 68.9 61.3 99.3 70.2 72.3 135.2 40.6 33.3 72.3 85.0 87.4 10.2 21.9 130.7 151.2 71.0 117.9 76.2 100.4 92.9 EIF4A3 "DDX48, EIF4AIII, Fal1, KIAA0111" ENSG00000141543 "Eukaryotic translation initiation factor 4A3" P38919 17 80134369-80147151 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, rRNA processing, Translation regulation, Transport" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021878 Supported Supported Nucleoplasm NA NA 280000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA021878: AB_1848090" "unprognostic (7.24e-2)" "unprognostic (7.33e-3)" "prognostic favorable (3.57e-5)" "unprognostic (1.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.68e-5)" "prognostic unfavorable (1.87e-4)" "unprognostic (3.71e-1)" "unprognostic (5.06e-2)" "unprognostic (4.64e-2)" "unprognostic (2.64e-2)" "unprognostic (9.78e-3)" "unprognostic (5.81e-2)" "unprognostic (9.20e-2)" "unprognostic (1.38e-2)" "unprognostic (2.91e-3)" 65.8 81.4 19.0 49.1 21.1 185.8 44.2 21.5 27.2 51.2 22.8 44.3 38.6 46.6 38.8 81.9 54.7 40.1 38.0 22.3 21.0 45.1 42.6 44.0 67.0 19.9 19.5 66.5 37.0 58.5 41.1 52.9 20.3 38.7 47.5 32.3 42.4 32.6 37.3 64.8 38.9 42.6 22.7 47.6 41.4 42.8 20.0 78.2 37.0 34.9 74.7 83.4 55.1 24.7 237.2 208.9 140.5 103.8 105.5 63.2 114.4 119.3 91.0 177.7 141.4 223.7 110.3 221.4 67.9 112.9 126.4 152.2 194.9 136.2 195.0 71.5 192.3 142.5 159.3 244.3 103.1 253.8 133.4 98.7 68.7 149.5 119.4 71.8 147.2 128.7 189.8 140.2 105.3 178.9 224.8 132.8 145.0 223.8 190.0 168.5 282.7 172.2 85.8 196.5 186.1 100.1 170.9 334.2 151.9 130.1 219.3 166.7 100.5 108.7 138.6 159.9 200.3 104.4 86.2 403.2 88.0 158.7 113.3 126.1 167.0 137.4 101.1 174.6 131.2 142.4 128.2 119.4 200.0 119.8 116.9 115.2 98.7 132.9 143.4 326.0 158.2 232.6 19.0 21.1 21.5 27.2 22.3 21.0 19.9 19.5 20.3 22.7 20.0 24.7 117.9 41.7 48.0 6.8 135.1 283.1 273.4 212.9 107.0 23.3 77.0 109.2 61.5 38.6 107.8 29.5 16.7 140.1 165.7 75.4 64.6 85.6 33.2 132.9 109.2 70.5 60.3 24.4 4.1 115.2 225.1 144.3 149.4 248.2 92.6 42.6 32.2 27.0 108.5 6.7 4.3 83.2 89.5 63.4 255.0 12.1 67.1 199.6 103.2 10.3 67.9 48.6 23.7 5.5 7.6 86.6 83.1 49.7 118.6 96.0 47.9 65.0 61.4 32.5 85.5 109.7 207.8 99.4 123.2 77.6 299.1 261.9 138.4 98.0 77.7 252.5 ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 70.4;Fibroblasts: 115.9;Leydig cells: 110.6;Peritubular cells: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 97.6;BJ: 143.7;fHDF/TERT166: 205.6;U-2197: 817.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 2900000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB010750: AB_476930, HPA018111: AB_1848109, HPA056941: AB_2683280" "unprognostic (1.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (2.72e-2)" "unprognostic (3.70e-3)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (2.00e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.62e-3)" 147.2 21.6 11.6 40.8 14.3 0.1 94.2 19.9 17.6 100.2 24.3 57.6 8.8 73.6 18.4 53.0 70.7 76.7 184.1 13.1 15.3 12.8 13.4 214.1 14.5 15.4 20.1 37.0 90.9 2.8 24.9 58.9 13.8 106.4 11.3 2.8 66.9 35.1 17.9 91.3 40.6 90.0 14.9 40.9 63.2 13.1 14.0 5.1 48.4 16.9 4.5 85.3 84.3 17.9 0.0 2.0 0.8 0.0 97.6 0.6 0.6 143.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 205.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.5 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.6 0.6 8.3 0.8 0.8 0.4 58.0 1.0 0.0 0.0 28.0 68.9 0.0 1.2 0.1 10.0 0.6 0.0 0.0 0.2 0.3 817.9 0.0 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 14.3 19.9 17.6 13.1 15.3 15.4 20.1 13.8 14.9 14.0 17.9 34.6 0.0 6.4 34.9 0.1 11.0 13.5 33.9 4.0 2.8 0.9 1.1 9.7 2.8 4.3 7.3 2.1 0.1 0.3 0.2 0.0 0.3 3.5 3.5 70.4 28.4 1.8 0.0 4.6 3.9 0.3 115.9 7.1 2.3 0.0 0.2 47.2 4.2 0.5 6.7 8.1 1.3 0.0 0.6 20.4 7.5 110.6 1.2 14.2 23.4 0.0 15.9 0.0 14.1 18.5 1.1 0.2 148.2 0.4 1.4 0.0 0.1 3.0 0.8 0.0 12.2 34.1 1.1 1.2 2.1 10.9 0.1 1.2 0.6 0.2 1.1 ELP4 "C11orf19, PAXNEB" ENSG00000109911 "Elongator acetyltransferase complex subunit 4" Q96EB1 11 31509755-31790324 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 37.9" "Cell type enhanced" "Detected in all" "Astrocytes: 153.5;Excitatory neurons: 93.6;Inhibitory neurons: 90.2;Microglial cells: 91.8;Oligodendrocyte precursor cells: 129.2;Oligodendrocytes: 123.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038572, HPA038573" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA038572: AB_2676090, HPA038573: AB_2676091" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (7.81e-2)" "unprognostic (1.61e-2)" "unprognostic (1.73e-1)" "unprognostic (3.10e-3)" "unprognostic (1.67e-2)" "unprognostic (1.87e-1)" "unprognostic (6.73e-2)" "unprognostic (8.13e-2)" "unprognostic (1.01e-1)" "unprognostic (5.33e-2)" "unprognostic (1.09e-2)" "unprognostic (2.15e-1)" "unprognostic (1.48e-1)" "unprognostic (8.38e-2)" "unprognostic (3.63e-2)" 7.1 7.2 14.6 7.4 16.4 8.6 6.8 37.9 19.0 7.4 13.3 9.0 4.6 6.8 8.3 9.7 7.3 7.2 10.2 14.0 13.3 10.2 9.6 7.3 9.7 13.6 14.3 7.5 9.4 8.1 5.4 7.8 14.7 6.7 7.7 12.7 6.9 7.4 8.3 9.6 6.5 7.6 13.6 6.4 6.5 8.3 15.2 15.1 6.6 8.3 8.4 7.8 7.3 18.2 13.2 11.2 12.0 14.4 10.9 14.9 4.6 11.5 12.3 16.7 18.4 10.4 11.5 18.0 9.7 10.3 20.9 23.3 16.5 14.4 18.3 15.1 18.3 5.9 13.2 16.0 11.2 12.6 11.2 14.9 8.7 7.2 19.5 13.2 20.4 22.9 27.4 15.7 10.7 20.3 21.4 14.9 6.9 38.9 13.7 12.8 25.7 12.0 25.6 13.0 13.8 6.4 22.3 13.4 10.0 11.7 25.4 18.2 8.2 15.3 13.5 25.3 15.2 6.1 12.9 22.0 10.8 17.6 13.4 5.9 8.0 8.1 6.7 9.2 8.3 9.1 7.6 7.9 9.3 5.9 8.5 7.4 2.1 7.5 9.5 8.3 10.1 6.6 14.6 16.4 37.9 19.0 14.0 13.3 13.6 14.3 14.7 13.6 15.2 18.2 13.9 12.8 10.5 153.5 11.4 8.3 11.0 20.2 6.8 4.9 7.7 8.5 7.7 5.7 14.5 7.3 4.2 20.2 11.4 4.3 29.4 9.1 18.0 11.0 14.0 7.5 6.7 4.6 93.6 11.3 15.6 10.5 4.1 8.3 10.8 12.8 3.9 5.5 11.5 15.2 90.2 6.0 12.2 5.7 2.4 3.6 5.0 8.5 3.6 91.8 7.7 16.5 8.2 129.2 123.4 6.1 3.9 6.4 14.3 2.9 4.0 33.1 8.6 6.1 6.6 8.3 12.9 23.5 10.2 9.4 8.2 18.9 11.4 11.6 6.4 6.9 EMC1 KIAA0090 ENSG00000127463 "ER membrane protein complex subunit 1" Q8N766 1 19215660-19251527 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 63.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048904 Approved NA NA 14000 "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA048904: AB_2680552" "unprognostic (9.46e-3)" "unprognostic (1.91e-3)" "unprognostic (1.75e-2)" "unprognostic (4.11e-3)" "unprognostic (2.05e-1)" "unprognostic (5.31e-3)" "prognostic unfavorable (8.56e-6)" "unprognostic (5.98e-2)" "unprognostic (1.69e-1)" "unprognostic (1.08e-1)" "unprognostic (4.96e-2)" "unprognostic (2.50e-1)" "unprognostic (3.02e-2)" "unprognostic (1.61e-1)" "unprognostic (1.54e-1)" "unprognostic (6.19e-2)" "prognostic unfavorable (1.43e-4)" 15.4 11.2 10.1 11.7 11.6 9.2 11.1 11.7 14.0 12.2 2.1 12.8 8.7 12.2 13.1 10.7 12.0 8.2 12.5 11.8 16.0 10.8 15.5 12.0 9.0 8.3 9.5 14.1 10.6 16.3 10.0 24.0 11.3 13.2 14.1 51.9 10.7 11.0 19.9 11.6 9.1 18.9 5.1 9.7 11.0 13.1 12.4 9.4 14.0 14.3 10.5 11.7 9.8 8.8 41.1 36.5 40.3 105.4 63.6 49.3 78.3 65.1 60.8 88.3 86.8 38.4 92.5 36.5 84.1 100.6 57.1 45.4 56.7 73.0 102.1 31.0 29.6 44.0 46.3 45.5 46.2 56.9 50.7 52.7 46.4 104.6 86.2 82.2 75.6 31.2 55.1 53.7 69.1 23.5 23.3 27.9 24.4 47.2 33.9 34.4 49.7 64.2 35.8 18.8 49.6 33.9 71.5 37.0 54.6 47.2 40.5 35.3 67.3 79.5 51.7 61.2 75.2 29.7 67.0 46.3 75.4 73.5 108.4 5.2 12.7 3.1 8.1 9.6 9.0 6.2 8.1 9.2 12.6 7.0 8.0 8.0 0.5 21.7 12.8 6.1 6.2 9.1 10.1 11.6 11.7 14.0 11.8 16.0 8.3 9.5 11.3 5.1 12.4 8.8 13.0 16.0 14.6 8.1 12.4 11.6 10.1 16.9 8.0 20.3 11.2 11.7 15.7 11.5 10.5 22.0 10.4 40.4 9.9 11.4 0.0 14.3 1.2 10.0 18.0 16.1 19.7 6.9 12.9 8.5 41.0 19.2 9.7 15.0 8.2 23.2 14.3 25.6 19.4 15.2 14.5 11.4 14.2 12.3 7.3 2.6 14.9 11.5 10.6 8.4 12.0 19.0 4.1 15.1 10.9 10.6 9.4 14.3 14.5 10.3 6.4 9.0 7.8 63.4 6.6 20.1 13.5 12.9 19.3 13.0 9.2 36.0 8.9 18.6 12.7 6.7 EMX2 ENSG00000170370 "Empty spiracles homeobox 2" Q04743 10 117542445-117549546 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 79.0;epididymis: 104.3" "Cell type enhanced" "Detected in many" "Collecting duct cells: 239.1;Distal tubular cells: 90.1;Endometrial ciliated cells: 75.6;Endometrial stromal cells: 126.5;Glandular and luminal cells: 68.6;Granulosa cells: 88.3;Proximal tubular cells: 185.0" "Group enriched" "Detected in many" 13 "endometrial cancer: 40.8;ovarian cancer: 52.8;renal cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 25.4;fHDF/TERT166: 31.6;RPTEC TERT1: 31.1;RT4: 9.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 13.3;basal ganglia: 14.2;cerebral cortex: 17.8;hippocampal formation: 22.8;white matter: 8.1" "HPA003497, HPA065294" Enhanced Supported Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA003497: , HPA065294: AB_2685455" "unprognostic (1.53e-1)" "prognostic favorable (2.80e-4)" "unprognostic (7.21e-3)" "unprognostic (5.41e-3)" "unprognostic (1.69e-1)" "unprognostic (3.53e-2)" "unprognostic (1.34e-1)" "unprognostic (2.41e-1)" "unprognostic (7.33e-2)" "unprognostic (1.76e-1)" "unprognostic (2.77e-1)" "prognostic favorable (2.28e-13)" "unprognostic (3.65e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (1.88e-2)" 10.4 0.1 23.2 0.2 25.6 0.2 2.8 16.9 31.3 58.2 16.7 0.4 0.1 79.0 104.3 0.4 53.0 1.5 0.8 26.9 16.5 39.1 0.1 0.1 0.6 15.8 18.0 11.9 0.0 0.1 1.8 0.4 16.4 1.1 0.1 0.3 2.4 52.6 10.8 10.5 0.1 45.0 14.7 0.2 0.1 1.2 19.6 0.1 0.3 5.2 0.4 4.7 4.4 22.9 0.0 0.0 0.0 2.6 0.0 0.3 0.1 1.9 0.0 0.0 0.0 0.0 0.1 0.0 25.4 31.6 0.0 0.1 0.6 0.0 0.0 0.1 2.8 0.8 0.1 0.2 0.0 0.1 0.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 6.1 0.2 31.1 9.4 0.2 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 2.6 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 23.2 25.6 16.9 31.3 26.9 16.5 15.8 18.0 16.4 14.7 19.6 22.9 4.6 0.0 0.0 43.4 1.0 10.7 2.0 0.0 0.0 0.0 0.1 0.5 1.0 0.0 0.0 239.1 0.0 0.2 0.0 0.1 90.1 0.0 1.4 75.6 126.5 3.1 0.0 0.0 0.1 0.0 0.3 18.0 0.0 68.6 0.0 88.3 0.0 0.0 0.6 0.0 0.1 0.2 0.0 0.0 8.0 2.6 60.3 2.5 21.4 1.9 0.0 0.0 0.0 1.5 0.1 0.0 0.0 41.0 0.0 2.5 0.1 185.0 0.0 0.1 52.6 8.6 32.1 0.3 0.3 0.0 7.5 0.1 2.2 2.2 0.3 1.7 ENG "CD105, END, HHT1, ORW, ORW1" ENSG00000106991 Endoglin P17813 9 127815013-127854658 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 528.7" "Cell type enhanced" "Detected in many" "Adipocytes: 407.5;Endothelial cells: 514.4;Extravillous trophoblasts: 294.4;Hepatic stellate cells: 579.0;Leydig cells: 487.1;Peritubular cells: 1421.8;Syncytiotrophoblasts: 376.4;Theca cells: 308.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 19.9;intermediate monocyte: 28.2;myeloid DC: 10.3;NK-cell: 7.6;non-classical monocyte: 22.1" "Group enriched" "Detected in many" 4 "dendritic cells: 10.3;monocytes: 28.2;NK-cells: 7.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 263.8;HUVEC TERT2: 487.4;TIME: 1027.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000096, HPA011862, HPA067440, CAB072873" Enhanced Supported "Nuclear bodies,Plasma membrane" NA NA 280000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nuclear bodies" "CAB000096: AB_563482, CAB072873: AB_2665725, HPA011862: AB_1846217, HPA067440: AB_2685840" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "prognostic favorable (6.61e-4)" "prognostic favorable (5.62e-6)" "unprognostic (2.15e-1)" "unprognostic (4.06e-1)" "unprognostic (3.87e-2)" "unprognostic (2.20e-2)" "unprognostic (8.98e-2)" "prognostic unfavorable (4.26e-4)" "unprognostic (3.33e-3)" "unprognostic (7.35e-2)" "unprognostic (2.84e-1)" "unprognostic (1.27e-1)" 234.5 92.6 44.4 80.2 41.5 18.8 164.8 45.2 44.5 129.7 50.4 62.4 33.2 111.1 35.1 43.1 122.4 58.7 528.7 36.7 43.1 211.6 60.7 260.7 43.4 50.0 47.1 220.9 47.1 29.7 56.1 93.6 52.8 93.9 17.5 2.1 46.2 73.5 72.3 51.3 76.8 65.7 43.1 226.5 57.6 98.9 59.4 17.3 169.2 54.8 17.7 93.0 95.8 43.6 1.3 1.0 7.1 0.4 117.8 81.0 217.8 147.1 102.0 74.4 43.4 0.5 1.3 1.0 70.2 263.8 56.8 2.4 0.0 23.2 24.5 0.7 0.3 42.3 76.7 4.6 91.7 20.2 0.5 137.6 5.4 97.7 34.9 1.0 487.4 1.4 0.7 1.4 88.1 0.9 0.6 1.8 1.7 0.3 4.2 66.9 12.5 1.4 0.0 0.4 0.8 1.8 78.0 65.3 20.1 4.7 13.8 29.8 1027.5 248.1 13.7 164.7 0.7 5.2 1.2 0.9 67.1 52.0 83.2 0.0 19.9 0.5 1.8 28.2 0.6 0.6 3.0 3.4 10.3 1.4 1.9 3.0 0.5 7.6 22.1 3.8 1.2 8.4 44.4 41.5 45.2 44.5 36.7 43.1 50.0 47.1 52.8 43.1 59.4 43.6 407.5 3.2 16.0 2.0 9.2 12.0 2.3 2.1 2.8 2.8 9.5 9.8 28.4 18.6 2.3 3.7 4.2 30.0 8.6 0.4 0.0 10.2 8.6 7.7 67.9 514.4 2.4 49.2 0.6 1.1 294.4 85.7 3.1 8.1 15.2 0.8 579.0 9.8 132.0 0.0 0.7 1.6 0.0 65.4 29.7 51.4 487.1 56.6 24.9 78.7 36.2 2.0 4.1 1.5 1.1 1.4 0.0 1421.8 2.1 2.0 0.0 0.3 5.1 4.6 72.3 44.0 57.5 4.4 5.2 1.3 8.4 376.4 9.6 308.1 0.5 1.4 EOGT "AER61, C3orf64, FLJ33770" ENSG00000163378 "EGF domain specific O-linked N-acetylglucosamine transferase" Q5NDL2 3 68975217-69013684 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Peritubular cells: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 86.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019460 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear membrane" Cytosol "HPA019460: AB_1844628" "unprognostic (2.62e-1)" "unprognostic (3.72e-1)" "unprognostic (1.07e-1)" "unprognostic (1.95e-2)" "unprognostic (8.96e-2)" "unprognostic (6.30e-2)" "unprognostic (2.18e-3)" "unprognostic (6.66e-2)" "unprognostic (1.13e-2)" "unprognostic (2.57e-1)" "unprognostic (1.68e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (8.97e-5)" "unprognostic (7.41e-2)" "unprognostic (4.67e-1)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" 19.4 9.1 7.2 12.8 7.2 5.9 19.5 6.7 10.9 14.0 22.4 25.8 7.4 29.9 9.8 17.5 18.5 17.8 28.5 7.1 7.0 10.2 5.7 28.7 8.2 7.7 7.6 11.6 12.6 5.0 9.3 22.3 8.0 27.9 8.6 8.8 16.4 33.7 20.0 9.7 11.4 25.4 7.8 10.0 15.5 8.9 7.8 11.1 7.9 15.2 8.8 24.7 13.7 7.5 19.0 7.1 12.5 14.4 16.6 32.2 8.6 25.4 31.5 16.0 21.0 9.1 10.2 1.1 3.8 28.1 13.6 6.0 8.3 32.3 19.9 62.3 5.6 20.2 15.5 13.5 18.7 11.5 8.2 26.8 29.4 20.6 25.1 19.4 86.2 0.8 5.9 11.1 53.7 5.5 2.0 3.8 13.5 6.2 3.5 0.8 12.4 8.2 13.9 43.4 1.2 6.3 29.1 1.7 23.5 12.8 6.0 15.9 44.6 40.6 13.4 5.1 24.3 6.0 20.5 9.3 16.3 17.1 23.8 5.4 1.5 0.0 2.0 1.4 2.3 1.1 3.0 4.3 2.4 0.7 2.5 2.7 0.2 2.4 0.5 0.4 6.6 1.3 7.2 7.2 6.7 10.9 7.1 7.0 7.7 7.6 8.0 7.8 7.8 7.5 29.6 12.8 10.3 14.0 3.5 7.1 11.4 13.2 16.5 2.2 7.5 11.7 20.7 4.3 14.5 1.8 16.7 0.9 3.1 5.1 0.0 4.6 16.5 15.3 7.5 23.7 6.0 3.8 11.2 8.2 5.3 9.3 9.2 15.4 0.0 9.4 20.3 3.6 6.7 0.0 21.4 4.5 2.0 6.8 9.8 15.1 3.1 8.6 8.8 30.9 6.5 1.4 1.0 9.5 12.2 12.4 3.4 40.6 5.4 8.3 2.1 1.9 13.2 5.6 0.0 26.8 15.2 5.5 2.5 14.8 4.5 0.8 7.0 6.9 3.4 8.6 EOMES TBR2 ENSG00000163508 Eomesodermin O95936 3 27715949-27722711 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Differentiation, Gastrulation, Immunity, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 8.4;lymphoid tissue: 15.0" "Cell type enhanced" "Detected in some" "dendritic cells: 43.6;Erythroid cells: 16.8;NK-cells: 93.7;T-cells: 31.5" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Region enriched" "Detected in single" 13 "cerebellum: 8.4" "Group enriched" "Detected in many" 7 "gdT-cell: 16.5;MAIT T-cell: 26.2;memory CD8 T-cell: 19.5;naive CD8 T-cell: 11.9;NK-cell: 33.0" "Group enriched" "Detected in many" 107 "NK-cells: 33.0;T-cells: 26.2" "Cell line enhanced" "Detected in some" "HDLM-2: 7.4;JURKAT: 8.3;SCLC-21H: 3.9" "Region enriched" "Detected in many" 8 "olfactory bulb: 77.5" "Group enriched" "Detected in some" 27 "cerebellum: 30.2;olfactory bulb: 12.7" HPA028896 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Golgi apparatus, Cytosol" "HPA028896: AB_10601370" "unprognostic (1.53e-4)" "unprognostic (5.95e-3)" "unprognostic (3.01e-2)" "unprognostic (1.60e-4)" "unprognostic (4.13e-2)" "unprognostic (9.63e-4)" "unprognostic (4.29e-4)" "unprognostic (3.14e-3)" "unprognostic (1.24e-1)" "unprognostic (2.82e-2)" "unprognostic (9.96e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.45e-6)" "unprognostic (1.61e-1)" "unprognostic (5.09e-1)" "unprognostic (6.32e-3)" "unprognostic (1.49e-2)" 1.0 0.6 0.2 3.2 0.1 1.8 0.6 8.4 0.4 0.4 0.4 0.7 0.4 0.8 0.8 0.3 0.4 1.6 0.3 0.2 0.3 0.4 2.4 2.2 15.0 0.2 0.3 0.5 0.3 0.1 0.2 0.4 0.6 0.5 0.8 1.6 0.9 0.1 0.1 0.2 1.4 0.4 0.3 12.8 1.3 0.4 0.2 1.5 0.5 0.1 5.4 1.3 0.4 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.6 1.3 0.0 7.4 1.1 0.0 0.0 0.5 0.0 0.9 0.0 0.0 0.8 0.0 0.9 0.3 0.0 8.3 0.2 0.0 0.0 2.0 2.0 0.0 0.2 0.2 0.9 1.3 0.0 0.0 0.6 0.0 3.9 0.0 0.0 0.0 0.9 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 16.5 0.0 26.2 0.0 3.0 19.5 0.0 0.0 0.2 11.9 0.2 33.0 0.1 0.1 0.0 2.9 0.2 0.1 8.4 0.4 0.2 0.3 0.2 0.3 0.6 0.3 0.2 0.4 0.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.4 0.2 0.3 0.8 1.5 0.0 0.0 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 16.8 0.0 0.0 0.0 0.3 0.5 0.1 0.0 0.0 2.2 1.6 0.2 0.0 0.0 0.0 0.0 3.1 0.7 0.0 0.3 1.3 1.8 1.0 1.1 0.1 93.7 0.0 0.0 0.0 0.0 0.4 9.8 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.7 0.0 2.0 0.0 0.1 0.0 31.5 0.0 0.0 0.0 EP300 "KAT3B, p300" ENSG00000100393 "E1A binding protein p300" Q09472 22 41092592-41180077 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000146, HPA003128, HPA004112" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746" "unprognostic (7.67e-2)" "unprognostic (5.56e-2)" "unprognostic (2.29e-1)" "unprognostic (2.52e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-1)" "unprognostic (2.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (8.97e-2)" "unprognostic (1.74e-2)" "unprognostic (8.54e-2)" "prognostic favorable (7.45e-5)" "unprognostic (7.97e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" 15.7 13.7 6.8 17.7 8.9 65.1 14.2 20.5 10.8 16.0 6.1 16.6 13.6 17.2 13.5 16.3 16.4 14.2 11.5 7.1 9.4 13.1 15.5 14.7 17.6 10.6 7.8 23.9 18.0 23.2 13.4 19.3 7.7 15.0 14.5 17.8 15.0 15.6 20.4 18.9 16.0 16.4 5.3 17.0 14.5 19.6 8.6 27.2 20.2 23.4 17.9 15.4 14.8 11.2 31.6 21.7 35.4 23.0 22.2 23.3 32.3 15.0 21.8 21.0 21.0 27.8 12.0 32.7 12.2 28.4 18.7 24.1 48.1 20.8 23.5 30.5 32.2 24.4 25.4 22.3 26.9 59.3 26.5 24.8 22.2 30.0 27.0 19.3 24.9 18.7 26.3 43.9 18.3 12.5 16.2 18.9 27.5 38.3 15.2 33.7 16.7 21.3 20.3 40.4 11.3 11.9 51.1 26.0 25.6 29.5 17.8 33.9 31.3 20.3 24.8 16.3 20.8 28.5 14.1 47.9 16.3 17.4 21.5 3.6 1.7 1.6 1.6 1.9 1.5 2.2 1.7 1.7 2.1 1.4 1.4 1.1 4.9 2.7 1.0 1.6 1.4 1.2 6.8 8.9 20.5 10.8 7.1 9.4 10.6 7.8 7.7 5.3 8.6 11.2 45.4 67.3 49.2 58.1 53.8 24.6 22.9 11.6 40.9 44.6 35.1 25.8 31.6 38.6 15.8 25.8 35.5 18.4 63.2 37.0 3.9 16.1 15.3 55.1 56.4 36.2 24.7 60.4 71.8 18.7 17.9 32.0 27.5 72.5 25.3 36.1 32.9 29.2 18.4 25.2 73.6 24.2 2.0 60.7 25.7 6.4 28.9 60.5 8.8 45.9 52.0 27.7 40.2 81.4 80.3 25.8 28.9 30.5 51.2 30.8 20.2 10.8 22.8 30.9 26.3 47.6 36.7 22.8 31.2 35.3 25.9 30.2 46.0 36.7 23.7 36.3 EPHB4 "HTK, Tyro11" ENSG00000196411 "EPH receptor B4" P54760 7 100802565-100827523 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Angiogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 68.5;Hepatic stellate cells: 113.2;Syncytiotrophoblasts: 206.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.0;neutrophil: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB013537 Uncertain NA NA 1400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB013537: " "prognostic unfavorable (8.56e-4)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (1.33e-1)" "unprognostic (5.23e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.84e-1)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (9.51e-3)" "unprognostic (6.63e-2)" "unprognostic (3.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (8.84e-4)" 26.4 49.8 5.0 8.0 4.3 5.6 32.6 4.6 4.8 45.6 6.8 20.7 8.3 61.5 3.8 24.7 27.1 18.0 26.1 4.1 4.1 28.3 33.3 28.2 5.8 5.5 5.1 36.0 26.8 10.1 6.3 35.5 5.3 28.9 10.2 0.3 24.2 22.4 7.7 35.8 17.5 22.2 5.1 47.9 21.4 12.3 6.3 3.1 17.6 13.3 4.9 17.3 28.1 4.8 37.7 33.1 32.5 94.2 20.4 13.0 94.7 14.1 31.2 22.3 29.0 27.4 28.3 4.8 63.6 15.3 31.3 38.2 14.3 38.3 11.9 6.2 25.6 1.3 19.0 43.2 11.8 0.7 0.9 15.3 56.7 14.2 33.1 24.8 84.0 1.5 71.9 1.8 18.4 66.4 0.7 15.0 54.7 56.3 47.5 51.4 15.6 8.9 28.6 19.9 0.2 27.4 22.0 10.4 22.1 45.1 26.1 6.7 71.3 27.6 42.6 51.3 21.4 0.2 0.8 1.7 4.0 12.0 51.2 0.0 2.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 4.3 0.0 0.1 0.1 0.0 0.7 5.0 4.3 4.6 4.8 4.1 4.1 5.5 5.1 5.3 5.1 6.3 4.8 47.1 9.6 12.6 1.6 1.9 20.5 10.3 13.9 15.9 0.1 22.0 19.7 5.7 7.2 8.5 5.5 0.0 68.5 1.1 9.1 0.0 12.3 28.5 4.8 21.8 51.2 3.0 10.8 0.3 6.6 11.2 6.5 12.8 8.0 1.3 10.7 113.2 22.4 9.0 0.0 0.2 17.4 8.2 4.1 3.4 9.9 8.1 1.3 3.6 1.9 1.5 1.7 0.0 0.0 1.0 20.6 7.6 4.1 1.4 13.3 1.3 4.0 4.2 0.2 6.6 5.7 6.3 1.4 10.2 12.1 17.8 206.5 1.2 2.9 19.9 8.0 EPS8L3 "FLJ21522, MGC16817" ENSG00000198758 "EPS8 like 3" Q8TE67 1 109750080-109764027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "gallbladder: 35.7;intestine: 142.1;stomach 1: 50.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 254.4;Gastric mucus-secreting cells: 80.5;Intestinal goblet cells: 103.4;Late spermatids: 144.6;Paneth cells: 257.8;Proximal enterocytes: 285.3;Undifferentiated cells: 112.6" "Group enriched" "Detected in many" 6 "colorectal cancer: 52.5;pancreatic cancer: 29.7;stomach cancer: 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 15.6;CAPAN-2: 14.4;Hep G2: 36.2;OE19: 67.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030998 Approved Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA030998: AB_2673691" "unprognostic (1.73e-3)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "unprognostic (2.76e-2)" "unprognostic (2.48e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (4.13e-5)" "unprognostic (5.55e-3)" "unprognostic (3.71e-2)" "unprognostic (2.09e-1)" "unprognostic (2.33e-1)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.87e-3)" "unprognostic (3.89e-1)" "prognostic favorable (1.82e-4)" 0.0 0.0 0.1 10.8 0.0 0.0 0.2 0.0 0.0 1.3 0.0 77.1 141.8 0.2 0.9 0.1 0.1 35.7 0.1 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 77.1 0.0 0.0 0.2 0.0 0.0 142.1 2.9 0.0 0.0 50.7 2.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.6 14.4 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 67.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 14.3 0.3 0.0 0.0 0.0 0.0 254.4 0.0 11.6 28.0 0.7 0.1 0.3 51.4 0.0 0.0 23.9 0.0 0.0 80.5 1.0 4.5 0.0 0.0 0.2 0.0 0.0 0.0 103.4 0.0 0.0 0.0 144.6 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.5 257.8 0.4 0.3 0.0 285.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.4 0.6 112.6 1.8 ERAL1 HERA-B ENSG00000132591 "Era like 12S mitochondrial rRNA chaperone 1" O75616 17 28855010-28861061 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "RNA-binding, rRNA-binding" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021425, HPA024423" Supported Enhanced Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" Mitochondria Cytosol "HPA021425: AB_1848228, HPA024423: AB_1848229" "unprognostic (1.03e-1)" "unprognostic (9.16e-2)" "unprognostic (5.36e-2)" "unprognostic (1.77e-2)" "unprognostic (3.55e-1)" "unprognostic (8.37e-3)" "prognostic unfavorable (3.59e-4)" "unprognostic (8.20e-2)" "unprognostic (7.04e-2)" "unprognostic (2.70e-1)" "unprognostic (8.57e-3)" "unprognostic (5.76e-1)" "unprognostic (1.08e-1)" "unprognostic (1.18e-1)" "unprognostic (2.49e-1)" "unprognostic (2.62e-1)" "unprognostic (5.79e-2)" 20.3 32.5 47.6 17.5 47.7 18.5 23.4 48.4 61.7 20.9 44.7 25.8 22.0 22.1 22.7 28.8 26.2 15.1 41.0 48.0 48.0 29.2 41.2 18.3 22.0 47.9 47.3 25.6 23.6 36.2 18.9 24.5 48.1 21.0 28.1 16.9 22.6 23.9 52.7 26.3 19.9 26.5 47.7 21.0 26.3 17.9 48.4 23.8 19.2 51.8 29.6 22.1 20.6 48.9 50.4 96.2 55.9 63.1 59.1 40.6 53.4 40.1 56.2 117.1 95.9 94.5 31.7 64.1 47.0 68.8 87.9 55.2 102.0 90.0 97.5 63.6 119.8 52.2 60.6 95.8 75.5 63.0 45.7 53.5 78.1 95.3 89.3 46.1 97.2 80.4 104.4 39.9 66.4 78.7 66.1 98.4 50.6 91.8 46.0 59.7 87.6 83.4 71.3 56.1 58.6 47.1 64.5 155.6 51.6 82.2 110.0 71.8 39.7 48.1 53.1 52.9 84.6 32.0 62.3 69.9 51.4 54.4 49.1 25.5 34.2 14.4 32.2 44.6 24.2 38.9 26.9 23.5 54.9 36.3 30.8 32.2 2.6 42.8 31.6 28.7 32.1 30.8 47.6 47.7 48.4 61.7 48.0 48.0 47.9 47.3 48.1 47.7 48.4 48.9 12.4 6.4 2.8 5.9 14.0 8.0 12.7 33.9 12.0 10.9 14.9 18.3 8.0 17.2 13.9 11.0 6.2 69.1 9.9 13.4 37.2 28.1 1.0 11.1 14.0 14.4 21.6 20.4 7.2 21.6 55.2 15.8 19.9 13.3 5.1 24.8 14.3 21.7 35.6 11.8 7.8 15.0 26.4 8.5 6.7 5.4 14.3 12.4 10.6 3.7 66.6 16.4 9.2 5.5 4.3 21.1 12.9 15.8 29.2 15.1 20.0 33.3 9.7 9.0 19.7 11.0 15.6 22.3 21.7 25.4 11.6 51.7 10.4 25.0 26.6 9.9 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 ERCC1 RAD10 ENSG00000012061 "ERCC excision repair 1, endonuclease non-catalytic subunit" P07992 19 45407334-45478828 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Cataract" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004390, HPA029773, HPA050182, CAB072859, CAB072860" Supported Enhanced Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "CAB004390: AB_2278023, CAB072859: AB_2665703, CAB072860: AB_2665704, HPA029773: AB_10602129, HPA050182: AB_2681044" "unprognostic (1.54e-3)" "unprognostic (5.99e-2)" "unprognostic (1.58e-1)" "unprognostic (1.34e-1)" "unprognostic (1.41e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (9.69e-4)" "unprognostic (2.57e-1)" "unprognostic (5.80e-2)" "unprognostic (7.37e-2)" "unprognostic (1.93e-2)" "unprognostic (2.75e-2)" "prognostic unfavorable (9.00e-5)" "unprognostic (6.19e-2)" "unprognostic (1.96e-1)" "unprognostic (1.60e-1)" "unprognostic (1.43e-1)" 47.0 49.8 34.7 28.0 33.9 31.4 50.7 37.6 42.6 50.5 44.8 45.1 26.2 47.9 40.2 43.1 43.7 30.3 109.1 35.9 37.2 57.8 38.3 40.4 30.0 38.7 35.5 54.2 57.1 48.9 56.9 22.9 37.3 55.2 20.8 23.2 70.6 29.2 84.0 63.3 40.1 33.4 35.4 43.1 42.9 27.8 36.2 24.1 46.9 83.1 30.5 41.5 44.3 36.6 61.1 104.0 84.2 125.8 57.8 108.1 27.3 90.1 119.1 106.4 141.4 12.0 58.8 34.5 24.9 94.2 57.2 45.0 26.0 277.7 65.1 79.1 28.6 57.9 39.3 36.2 120.2 55.9 96.8 81.0 60.3 111.7 99.5 89.0 117.3 40.8 33.8 69.8 167.9 40.3 50.9 44.4 20.9 54.4 42.4 77.7 40.5 46.3 78.5 36.7 36.6 76.2 58.4 47.3 79.6 27.7 55.0 103.7 70.3 97.7 91.4 59.2 93.8 49.5 43.2 39.5 105.3 45.8 296.6 30.7 131.9 26.3 61.3 142.8 41.7 75.8 37.3 48.6 134.7 84.1 29.4 47.4 17.8 60.6 107.9 315.8 49.8 90.2 34.7 33.9 37.6 42.6 35.9 37.2 38.7 35.5 37.3 35.4 36.2 36.6 43.2 22.4 36.3 13.1 53.4 70.9 109.7 82.7 41.5 0.0 73.9 76.8 39.1 37.1 43.9 20.2 0.0 36.1 67.8 26.9 90.1 54.5 27.1 50.4 43.5 37.5 39.6 20.2 32.9 65.9 33.3 62.4 22.4 24.5 50.0 103.4 38.9 29.6 96.2 0.0 21.9 41.2 34.6 61.5 71.7 107.1 79.2 69.6 67.6 17.8 49.0 0.0 38.1 16.6 13.8 85.3 33.5 57.2 49.1 94.9 69.2 73.1 67.5 0.0 46.0 60.5 60.0 37.0 37.1 51.4 52.8 35.6 36.0 98.6 43.2 89.0 ERCC2 "EM9, MAG, MGC102762, MGC126218, MGC126219, XPD" ENSG00000104884 "ERCC excision repair 2, TFIIH core complex helicase subunit" P18074 19 45349837-45370918 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 34.1;Spermatocytes: 30.5;Theca cells: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005375, HPA038057, HPA069266" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 43: Testis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Cytosol "CAB005375: AB_2100152, HPA038057: AB_2675810, HPA069266: AB_2686104" "unprognostic (1.10e-1)" "unprognostic (5.48e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-3)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (1.06e-1)" "prognostic favorable (3.26e-4)" "unprognostic (3.36e-2)" "unprognostic (2.44e-3)" "unprognostic (1.94e-1)" "unprognostic (5.47e-1)" "unprognostic (8.99e-2)" "unprognostic (3.45e-2)" 6.8 13.0 10.5 6.9 10.3 4.8 6.5 8.4 11.7 7.5 8.4 7.5 4.9 9.7 3.2 6.3 8.0 4.1 7.0 10.8 9.3 7.6 9.0 5.8 5.8 10.6 9.9 7.8 7.7 7.7 9.7 4.5 9.6 6.7 4.0 3.1 7.3 6.7 11.7 7.2 6.6 6.9 8.1 8.1 7.5 13.9 10.1 5.3 8.4 6.3 5.2 7.5 5.9 8.9 28.0 13.3 27.1 38.4 16.3 19.4 15.2 38.8 27.4 50.2 40.2 32.6 18.6 10.0 21.6 39.9 19.1 14.0 19.1 32.9 18.5 24.4 31.8 16.9 26.8 35.4 33.3 27.1 28.4 22.4 5.6 55.8 31.9 28.2 29.1 28.8 41.8 10.9 34.8 14.7 16.1 17.9 12.7 27.2 24.6 30.3 19.4 8.3 14.0 24.9 15.8 17.1 34.2 23.9 13.6 20.6 22.8 35.4 37.9 46.4 25.3 19.9 88.0 24.9 15.8 14.2 13.8 16.4 21.2 0.0 17.2 6.5 9.1 18.0 11.9 9.1 8.9 8.9 21.8 6.5 8.2 8.7 0.5 15.6 14.9 10.4 9.8 12.1 10.5 10.3 8.4 11.7 10.8 9.3 10.6 9.9 9.6 8.1 10.1 8.9 4.2 6.4 3.4 6.2 5.8 6.2 5.5 8.6 4.6 0.0 6.1 4.3 6.7 8.6 8.7 5.5 0.0 10.5 4.1 5.9 13.7 10.7 4.7 3.3 4.5 5.5 7.2 5.5 2.9 8.2 12.1 6.8 6.1 3.8 0.0 34.1 7.9 12.3 11.5 0.0 3.1 8.5 4.1 8.2 4.2 2.8 6.5 6.3 3.6 1.0 4.2 0.0 5.2 5.0 1.4 8.1 3.1 7.9 7.5 4.2 4.1 13.0 7.5 0.0 0.0 3.5 9.9 30.5 13.1 5.1 5.7 4.8 4.7 29.1 8.8 3.2 ERCC3 "BTF2, RAD25, XPB" ENSG00000163161 "ERCC excision repair 3, TFIIH core complex helicase subunit" P19447 2 127257290-127294166 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037153, HPA046077" Approved Enhanced Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "CAB037153: AB_796181, HPA046077: AB_2679527" "unprognostic (2.31e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-3)" "unprognostic (1.05e-1)" "unprognostic (8.85e-2)" "prognostic unfavorable (1.62e-7)" "unprognostic (2.74e-1)" "unprognostic (9.13e-3)" "unprognostic (9.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.46e-2)" "prognostic unfavorable (4.30e-6)" "unprognostic (3.71e-1)" "unprognostic (8.50e-2)" "unprognostic (5.73e-2)" "unprognostic (3.92e-2)" 24.4 25.9 15.0 14.5 16.0 19.8 24.4 15.1 16.5 32.2 19.6 28.9 9.6 27.0 11.6 22.7 28.9 14.2 23.4 16.6 14.9 22.8 22.2 22.1 21.6 15.7 14.8 29.5 23.8 26.3 33.8 13.6 16.0 27.4 13.8 4.4 23.2 16.8 35.3 27.7 24.3 21.5 15.1 32.6 23.7 29.8 15.6 26.6 25.0 25.6 22.4 27.2 26.4 15.2 45.9 30.8 37.8 40.6 40.6 27.8 46.4 41.3 52.9 65.1 62.5 48.1 32.9 34.5 33.2 37.8 41.7 40.2 57.7 43.3 56.1 54.4 51.4 43.6 35.8 51.0 30.5 38.1 45.4 28.9 39.8 75.7 32.4 41.5 42.4 44.3 43.0 22.1 41.7 45.1 54.8 42.2 55.0 29.2 47.3 44.5 42.7 28.8 36.4 42.2 45.2 49.2 35.3 52.6 55.0 42.4 28.7 43.0 34.1 39.2 45.2 35.8 49.7 39.2 81.5 54.0 34.3 18.0 42.8 8.0 11.5 8.8 18.2 12.0 18.4 13.7 13.1 15.7 16.9 12.7 17.7 12.2 3.5 25.0 9.9 13.6 20.5 15.5 15.0 16.0 15.1 16.5 16.6 14.9 15.7 14.8 16.0 15.1 15.6 15.2 12.2 22.4 14.6 24.8 17.7 7.6 9.5 20.6 21.1 0.0 13.0 11.6 13.0 5.7 25.4 7.3 0.0 18.6 18.9 6.1 1.9 13.7 9.0 22.9 13.9 12.2 6.1 3.8 22.3 14.9 12.2 16.6 18.8 13.1 10.1 17.1 15.4 8.6 14.6 0.0 23.5 10.0 14.2 12.5 7.6 5.1 16.4 10.7 8.8 10.3 12.3 0.0 14.4 18.1 22.4 15.5 7.3 12.8 16.4 7.4 6.3 8.5 45.2 0.0 13.1 17.6 13.3 41.1 31.0 11.3 9.5 14.6 15.7 12.3 10.6 8.5 ERCC4 "FANCQ, RAD1, XPF" ENSG00000175595 "ERCC excision repair 4, endonuclease catalytic subunit" Q92889 16 13920154-13952348 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Cockayne syndrome, Disease variant, Dwarfism, Fanconi anemia, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 18.5" "Cell type enhanced" "Detected in many" "Early spermatids: 140.7;Late spermatids: 117.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000156, HPA045828" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Plasma membrane" "CAB000156: , HPA045828: AB_2679463" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "unprognostic (2.12e-3)" "unprognostic (9.41e-2)" "unprognostic (3.35e-1)" "unprognostic (1.40e-2)" "unprognostic (1.64e-2)" "unprognostic (2.26e-1)" "unprognostic (3.59e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (8.49e-2)" "unprognostic (5.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (6.30e-2)" "unprognostic (5.88e-4)" 2.7 3.9 4.7 3.3 5.2 2.5 2.8 6.7 5.4 3.3 4.3 1.9 1.7 3.3 2.8 2.9 3.5 3.0 3.6 4.3 4.9 2.9 3.2 2.7 3.3 5.1 4.8 4.3 2.7 3.9 1.6 2.6 4.9 3.6 2.2 4.1 2.8 2.9 18.5 3.0 1.9 3.6 4.4 3.7 2.6 5.5 5.4 4.2 4.4 3.3 2.9 2.6 1.5 6.8 4.7 5.5 5.3 7.5 8.7 8.1 4.0 6.1 6.4 5.4 6.8 2.1 4.5 7.8 8.6 5.4 4.8 5.8 8.0 4.1 8.3 10.7 4.7 3.8 6.7 5.2 7.9 5.2 4.2 6.1 5.7 7.1 6.0 5.3 7.2 4.6 6.1 8.8 7.6 3.9 7.0 3.4 3.9 2.4 3.1 7.8 10.8 9.7 3.3 3.2 4.3 5.1 7.5 6.0 5.8 4.2 7.5 3.9 7.9 7.8 5.7 7.0 5.4 7.9 9.9 5.2 7.6 6.2 8.1 4.9 2.3 2.3 2.6 2.7 2.9 2.5 2.4 2.0 2.3 3.1 2.4 2.6 2.7 3.6 2.4 3.2 2.5 1.1 4.7 5.2 6.7 5.4 4.3 4.9 5.1 4.8 4.9 4.4 5.4 6.8 14.0 19.2 13.5 16.6 11.3 4.8 6.1 18.3 10.2 0.0 10.0 9.5 8.6 14.3 12.7 5.5 0.0 17.3 9.7 3.3 9.8 11.6 140.7 18.6 19.0 13.5 9.6 12.0 20.4 8.4 6.2 13.0 5.1 7.4 1.3 17.8 17.2 17.7 11.7 0.0 21.2 4.8 10.2 13.6 6.5 117.9 14.9 11.4 10.6 8.4 14.4 0.0 17.5 12.1 20.1 9.9 1.7 21.1 14.4 10.2 4.4 13.3 26.1 0.0 26.3 17.3 12.2 49.4 28.9 9.2 5.5 12.3 11.8 18.0 6.0 4.7 ERCC5 "ERCM2, XPGC" ENSG00000134899 "ERCC excision repair 5, endonuclease" P28715 13 102845831-102875995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.7;Gastric mucus-secreting cells: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA045845, HPA050374" Supported Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "HPA045845: AB_2679471, HPA050374: AB_2681106" "unprognostic (1.28e-3)" "unprognostic (1.32e-3)" "unprognostic (1.86e-2)" "unprognostic (9.28e-3)" "unprognostic (6.19e-2)" "unprognostic (8.73e-2)" "unprognostic (1.23e-1)" "unprognostic (8.72e-2)" "unprognostic (2.52e-1)" "unprognostic (2.55e-1)" "unprognostic (7.77e-3)" "unprognostic (5.76e-3)" "prognostic unfavorable (2.96e-6)" "unprognostic (3.56e-2)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "prognostic favorable (6.82e-4)" 14.1 11.1 7.8 10.9 8.6 16.3 14.5 8.9 11.8 12.2 10.5 14.5 20.1 9.2 13.4 10.7 9.7 10.8 9.8 8.1 8.2 12.6 21.8 12.8 15.2 8.5 8.2 12.5 11.3 12.3 3.7 11.3 8.5 11.7 14.3 12.6 10.5 10.8 9.5 13.2 17.1 9.6 8.0 15.2 16.3 7.0 8.4 21.3 13.5 10.8 16.5 11.2 3.9 8.4 21.5 10.5 15.4 7.4 34.4 30.5 8.9 24.5 31.1 13.6 16.7 10.8 37.9 19.3 10.4 23.4 9.4 23.8 14.3 19.6 10.1 19.4 9.7 16.6 23.7 13.3 15.9 50.9 26.3 26.1 19.2 15.7 25.6 19.6 23.1 23.4 9.5 16.5 23.9 8.0 18.7 23.5 7.7 30.2 9.9 14.9 10.9 17.9 19.3 15.7 9.0 14.1 12.6 25.0 8.8 13.6 13.9 43.4 21.4 7.5 5.5 3.7 13.1 16.1 5.0 9.4 41.3 20.7 10.9 19.2 11.9 20.4 16.2 15.0 14.6 8.9 17.1 19.8 14.3 8.8 18.4 18.2 3.5 20.5 21.1 7.4 20.7 17.7 7.8 8.6 8.9 11.8 8.1 8.2 8.5 8.2 8.5 8.0 8.4 8.4 2.2 3.2 9.5 0.0 22.2 7.1 4.7 11.5 16.5 0.0 2.0 2.0 28.6 14.3 14.0 0.0 0.0 9.6 7.3 17.6 0.0 1.6 60.7 2.4 4.8 8.6 4.9 24.8 0.0 1.2 7.5 11.0 44.9 2.1 19.0 1.7 13.2 21.2 10.5 0.0 0.0 22.3 10.2 17.2 6.5 28.3 22.1 14.0 7.2 0.0 12.6 0.0 19.6 0.0 0.0 1.7 16.7 15.8 21.5 4.0 26.6 1.5 11.4 0.0 19.7 10.6 6.7 11.6 6.3 19.1 7.0 5.7 31.3 1.7 18.2 5.0 ERCC6 "ARMD5, CKN2, CSB, RAD26" ENSG00000225830 "ERCC excision repair 6, chromatin remodeling factor" "P0DP91, Q03468" 10 49454168-49539538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Age-related macular degeneration, Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Mental retardation, Premature ovarian failure, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 53.8;hTERT-RPE1: 123.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071297 Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies" "HPA071297: AB_2732177" "unprognostic (1.92e-2)" "unprognostic (1.85e-1)" "unprognostic (9.79e-3)" "unprognostic (7.26e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-2)" "unprognostic (3.03e-2)" "unprognostic (2.99e-2)" "unprognostic (1.71e-2)" "unprognostic (1.13e-1)" "unprognostic (1.80e-1)" "unprognostic (4.57e-2)" "unprognostic (1.04e-1)" "unprognostic (8.61e-2)" "unprognostic (4.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" 2.7 2.1 1.6 1.9 1.5 4.6 3.8 3.0 2.3 3.1 7.7 2.4 2.0 3.0 1.5 3.8 2.9 2.7 3.4 1.2 1.1 3.2 3.3 2.7 2.9 2.4 1.9 4.5 3.1 5.9 2.8 3.4 2.1 3.3 2.7 3.1 3.2 2.2 3.5 4.6 2.5 2.3 2.2 2.9 2.4 3.1 2.1 3.3 5.1 3.6 3.4 2.6 3.3 1.9 11.2 5.5 4.1 2.1 6.6 10.5 3.4 21.2 27.1 14.1 9.9 6.2 5.6 4.9 3.7 18.7 6.7 9.5 6.3 16.6 13.5 8.4 4.1 3.9 21.7 3.4 3.9 5.0 3.7 4.3 17.2 12.9 53.8 123.4 19.8 2.9 6.8 0.8 16.8 8.3 3.4 2.0 4.0 3.5 10.2 2.3 5.8 2.6 4.1 7.1 5.9 4.7 15.4 3.6 8.2 9.4 7.1 2.7 38.9 7.0 5.5 8.6 5.2 3.3 4.5 4.1 7.3 5.0 5.1 13.1 3.0 7.5 4.1 2.6 3.0 6.8 2.3 2.2 3.9 5.2 2.8 1.4 7.2 1.2 5.3 2.2 3.1 1.8 1.6 1.5 3.0 2.3 1.2 1.1 2.4 1.9 2.1 2.2 2.1 1.9 6.9 16.0 13.2 14.7 6.0 3.6 1.4 1.5 5.2 0.0 7.1 7.1 7.1 5.7 8.2 9.2 0.0 2.5 10.9 4.8 5.9 5.2 11.3 8.1 8.7 5.1 1.2 1.3 24.3 6.0 2.1 4.9 2.0 10.1 7.6 8.9 5.3 4.3 2.6 0.0 21.7 5.3 0.0 4.4 2.6 15.3 2.8 8.0 1.8 23.4 11.2 0.0 4.1 17.6 16.6 5.2 2.6 2.2 3.6 2.5 5.0 3.6 9.0 0.0 6.6 4.4 4.2 5.3 5.0 3.5 4.1 1.8 7.4 11.4 2.8 1.9 ERCC8 "CKN1, CSA" ENSG00000049167 "ERCC excision repair 8, CSA ubiquitin ligase complex subunit" Q13216 5 60866454-60945073 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Cockayne syndrome, Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 47.3;Excitatory neurons: 51.8;Inhibitory neurons: 47.9;Oligodendrocyte precursor cells: 44.2;Oligodendrocytes: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029328 Approved "Nuclear speckles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "HPA029328: AB_2673000" "unprognostic (5.45e-2)" "unprognostic (1.90e-1)" "unprognostic (2.56e-2)" "unprognostic (6.59e-2)" "unprognostic (1.68e-2)" "unprognostic (4.96e-2)" "unprognostic (2.10e-3)" "unprognostic (9.68e-2)" "unprognostic (3.85e-2)" "unprognostic (3.23e-1)" "unprognostic (7.49e-2)" "unprognostic (1.09e-1)" "unprognostic (4.75e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (6.31e-3)" "unprognostic (7.19e-2)" 3.4 3.1 2.3 1.6 2.4 2.0 3.1 3.1 3.2 2.5 1.5 2.6 1.7 3.0 1.4 2.8 2.4 1.9 3.2 2.3 1.7 4.0 3.2 2.2 1.6 1.9 1.8 2.7 2.7 3.0 2.5 2.1 2.1 2.2 2.4 2.7 2.7 2.1 3.0 2.4 2.2 2.3 1.4 2.6 2.5 4.1 2.0 2.8 2.9 2.9 2.2 2.5 2.6 2.9 4.8 4.9 7.3 9.5 6.0 4.2 8.2 7.6 6.4 8.9 9.2 6.9 8.6 7.3 9.4 4.2 14.4 4.0 10.6 7.4 11.1 7.6 6.0 5.3 7.3 7.7 5.0 4.9 4.5 6.5 6.5 6.1 7.5 3.3 9.9 8.8 8.0 4.2 5.2 8.1 6.9 8.0 6.5 2.8 3.1 11.0 9.6 9.1 4.7 5.9 6.1 11.3 8.6 3.6 6.5 7.6 11.2 3.6 3.8 3.8 7.4 7.6 10.1 5.5 11.9 12.7 5.9 10.1 8.3 0.5 4.2 0.9 3.1 3.4 2.5 2.7 2.4 2.8 7.1 1.8 2.8 3.2 0.7 2.2 1.4 3.5 3.3 2.1 2.3 2.4 3.1 3.2 2.3 1.7 1.9 1.8 2.1 1.4 2.0 2.9 3.4 3.2 4.6 28.4 6.6 2.9 3.1 6.9 9.6 0.0 4.9 5.5 4.1 7.2 3.3 16.5 0.0 7.7 4.2 1.6 15.6 5.0 47.3 4.3 7.2 3.9 0.0 10.5 51.8 5.2 9.2 5.2 5.1 3.1 5.7 8.1 3.9 5.0 6.4 0.0 47.9 3.8 4.1 7.1 5.5 11.2 4.7 6.5 7.2 20.6 7.9 0.0 6.2 44.2 57.4 5.2 2.2 3.0 11.1 3.8 2.0 7.1 6.3 0.0 0.0 4.0 4.6 22.5 9.2 10.4 4.3 3.4 6.5 8.9 4.4 3.5 ERF "PE-2, PE2" ENSG00000105722 "ETS2 repressor factor" P50548 19 42247569-42255128 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 157.0;Suprabasal keratinocytes: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058532, HPA067952" Approved Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA058532: AB_2683744, HPA067952: AB_2685932" "prognostic favorable (8.07e-4)" "unprognostic (2.86e-1)" "unprognostic (1.47e-2)" "unprognostic (9.07e-2)" "unprognostic (5.21e-2)" "unprognostic (6.66e-2)" "unprognostic (2.21e-1)" "unprognostic (7.27e-3)" "unprognostic (3.61e-2)" "unprognostic (2.20e-1)" "unprognostic (8.63e-3)" "unprognostic (3.24e-1)" "unprognostic (6.41e-2)" "unprognostic (1.63e-1)" "unprognostic (2.85e-1)" "unprognostic (1.91e-2)" "unprognostic (1.54e-2)" 38.2 31.8 21.1 21.9 23.7 15.2 35.1 16.5 24.3 35.8 10.4 37.1 34.4 48.2 17.4 25.6 49.9 50.1 37.8 19.5 23.9 37.5 43.4 41.6 20.0 22.3 22.5 43.0 29.1 21.0 40.3 18.5 19.5 30.9 10.0 14.6 26.4 17.2 11.6 33.5 34.4 19.9 17.5 31.4 29.8 32.8 21.9 24.2 38.7 18.0 15.6 29.7 31.3 37.7 57.6 136.4 57.7 65.8 12.7 32.4 16.4 53.3 37.4 53.5 54.0 63.2 65.1 47.4 32.9 49.3 48.0 61.7 42.1 124.4 39.2 23.5 29.1 28.5 82.9 80.1 34.3 33.2 45.5 37.1 41.3 41.4 45.5 69.6 45.0 37.9 62.0 38.4 29.8 115.8 38.0 25.0 48.5 54.4 29.3 46.6 21.0 20.1 33.5 49.1 26.6 54.2 59.4 43.4 61.8 39.1 43.6 58.7 54.2 78.4 112.9 27.4 100.0 43.2 53.1 39.0 76.9 35.3 108.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 21.1 23.7 16.5 24.3 19.5 23.9 22.3 22.5 19.5 17.5 21.9 37.7 63.3 3.2 1.7 7.8 25.0 157.0 30.2 19.8 77.4 14.1 95.0 57.9 7.3 25.8 6.3 9.2 22.9 7.2 21.7 21.6 7.9 19.1 9.4 35.1 20.5 43.7 26.4 7.8 4.2 15.8 4.9 27.2 13.7 23.4 11.4 10.0 41.4 30.2 11.7 10.1 1.5 22.9 2.0 14.5 58.6 4.1 11.1 22.9 55.2 7.5 7.3 19.0 3.1 3.5 8.5 15.3 27.2 10.1 11.2 18.8 34.6 23.3 11.9 12.3 13.1 61.0 39.8 3.0 16.2 37.9 109.7 14.8 25.5 10.2 21.7 17.6 ERGIC1 "ERGIC-32, ERGIC32, KIAA1181, NET24" ENSG00000113719 "Endoplasmic reticulum-golgi intermediate compartment 1" Q969X5 5 172834251-172952683 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 247.8;Intestinal goblet cells: 202.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018666, HPA018900" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Vesicles" "HPA018666: AB_1848241, HPA018900: AB_1848242" "unprognostic (8.86e-2)" "unprognostic (3.50e-2)" "unprognostic (3.44e-2)" "unprognostic (5.71e-2)" "unprognostic (7.96e-2)" "unprognostic (2.46e-2)" "unprognostic (9.53e-3)" "unprognostic (7.02e-3)" "unprognostic (2.06e-1)" "unprognostic (6.25e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "unprognostic (1.74e-2)" "unprognostic (1.67e-1)" "unprognostic (3.86e-2)" "unprognostic (9.28e-2)" "unprognostic (3.22e-2)" 67.3 147.8 33.4 49.1 31.2 44.9 60.3 47.4 35.4 127.2 26.7 97.7 79.5 67.4 75.3 55.0 72.4 50.2 60.9 35.8 31.8 66.1 193.2 77.8 40.8 41.4 36.4 56.9 80.6 50.7 48.5 47.9 38.1 146.8 102.7 21.6 97.6 69.8 92.3 46.7 79.4 64.1 33.0 69.2 107.1 25.3 41.3 83.1 75.2 91.9 55.0 58.3 54.3 34.0 120.2 112.8 95.0 211.6 353.3 262.0 51.9 239.5 179.3 105.5 97.4 159.5 120.4 114.8 166.9 406.4 181.7 43.2 68.5 316.8 123.3 92.0 67.5 70.7 156.1 86.1 258.9 33.3 21.6 223.8 128.6 155.8 143.8 173.8 171.0 117.8 42.6 156.8 177.1 150.4 96.5 57.6 56.0 283.7 101.4 327.4 62.9 358.5 245.2 68.6 52.9 96.0 82.7 234.7 120.6 91.1 98.0 37.4 132.4 171.3 69.1 165.9 99.2 246.8 294.0 47.5 236.9 78.3 76.2 3.7 7.5 19.2 3.1 10.5 5.2 9.3 1.6 2.1 6.1 6.2 1.0 2.3 30.6 14.3 14.3 3.1 1.0 5.1 33.4 31.2 47.4 35.4 35.8 31.8 41.4 36.4 38.1 33.0 41.3 34.0 41.9 57.7 29.5 22.9 62.0 22.8 32.1 22.7 14.8 37.2 51.2 35.1 32.9 68.6 29.4 49.7 16.7 20.7 44.3 83.6 21.5 101.9 11.5 36.2 48.0 33.5 26.0 25.9 35.4 60.8 90.3 47.2 49.5 77.9 23.5 64.4 37.5 247.8 41.1 21.9 41.8 202.9 36.7 77.0 105.2 33.8 65.0 54.8 7.2 30.0 91.1 39.0 36.0 47.7 30.6 86.9 59.3 58.3 96.2 74.2 95.0 38.5 28.4 12.6 39.5 56.1 41.1 1.9 10.5 27.2 26.9 9.0 25.1 103.5 73.3 47.8 ERMARD "C6orf70, dJ266L20.3, FLJ11152" ENSG00000130023 "ER membrane associated RNA degradation" Q5T6L9 6 169751622-169781600 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 49.9;Late spermatids: 48.5;Spermatocytes: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041741 Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA041741: AB_10804116" "unprognostic (2.66e-3)" "unprognostic (2.75e-1)" "unprognostic (2.33e-1)" "unprognostic (2.28e-2)" "unprognostic (1.18e-1)" "unprognostic (3.18e-1)" "unprognostic (2.24e-2)" "unprognostic (7.41e-3)" "unprognostic (1.96e-1)" "unprognostic (8.14e-2)" "unprognostic (1.66e-3)" "unprognostic (4.74e-2)" "unprognostic (3.06e-2)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.31e-2)" 13.8 14.6 5.3 8.4 7.1 10.1 13.1 5.4 6.7 13.7 5.6 11.2 6.3 13.8 20.5 10.5 13.2 7.7 6.8 5.3 5.9 16.1 18.6 9.7 13.8 6.9 6.1 17.4 11.4 6.9 15.4 7.4 7.2 12.7 7.4 14.6 11.0 8.6 14.9 18.7 13.6 6.4 6.5 17.3 10.9 22.1 6.1 9.9 13.2 2.5 13.6 11.2 10.8 9.1 5.1 7.5 9.7 14.8 6.9 11.4 5.1 5.3 7.7 5.0 6.3 2.0 8.3 8.0 4.8 6.5 6.1 13.3 4.0 10.3 4.4 8.6 4.4 11.5 9.9 3.0 13.7 16.1 7.6 13.4 10.4 6.1 15.5 12.8 3.4 14.0 8.0 11.4 6.5 7.7 6.8 14.4 3.2 5.7 5.4 7.5 6.0 13.0 6.2 4.0 3.8 7.0 9.0 9.0 4.9 6.3 7.1 12.8 5.3 5.7 3.4 9.1 6.5 13.1 17.5 6.7 7.2 9.7 6.6 1.6 4.2 1.8 5.2 7.9 5.2 5.1 6.0 5.9 4.4 6.0 4.7 4.4 0.4 5.2 9.7 3.7 7.6 3.9 5.3 7.1 5.4 6.7 5.3 5.9 6.9 6.1 7.2 6.5 6.1 9.1 8.5 3.2 11.1 20.2 6.2 4.1 4.4 7.7 5.2 12.0 5.9 5.1 2.8 5.7 7.7 5.5 10.4 12.2 4.7 3.0 11.7 9.8 49.9 10.8 9.4 5.0 6.0 4.6 9.3 8.5 8.3 7.0 5.6 6.9 2.5 11.7 7.9 10.1 5.9 5.0 11.8 2.9 6.1 5.7 4.4 48.5 4.4 6.1 3.6 8.4 5.6 14.6 5.2 17.1 20.7 5.3 2.4 4.5 4.4 2.5 5.7 9.5 15.5 10.8 6.6 5.5 5.8 37.8 18.0 5.5 3.1 7.1 4.7 10.3 3.4 3.4 ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;intestine: 11.0;lymphoid tissue: 8.5;testis: 5.7" "Group enriched" "Detected in many" 4 "Erythroid cells: 44.6;Spermatocytes: 62.0;Spermatogonia: 80.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "Cell Junctions" "HPA027243: AB_2672175, HPA053679: AB_2682227" "unprognostic (7.86e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.04e-4)" "unprognostic (5.13e-3)" "unprognostic (9.50e-2)" "unprognostic (8.67e-3)" "unprognostic (7.30e-4)" "unprognostic (5.24e-3)" "unprognostic (2.24e-2)" "unprognostic (2.54e-2)" "unprognostic (7.51e-4)" "unprognostic (2.23e-1)" "unprognostic (1.65e-14)" "unprognostic (6.65e-3)" "unprognostic (5.32e-1)" "unprognostic (5.85e-2)" "unprognostic (4.06e-1)" 0.5 0.4 0.0 2.7 0.2 6.0 1.2 0.4 0.2 0.5 0.0 3.7 11.0 0.6 0.0 2.4 0.2 0.6 0.2 0.0 0.0 0.1 0.7 0.4 4.6 0.0 0.0 0.1 1.0 0.3 0.0 1.1 0.1 0.3 4.3 0.5 0.3 0.1 0.0 1.1 7.9 0.7 0.0 0.8 2.5 5.7 0.0 8.5 0.3 0.2 5.7 0.8 0.5 0.2 54.6 39.9 17.9 22.0 2.3 3.9 10.2 31.6 12.9 27.8 32.5 14.2 10.7 21.0 16.6 8.3 24.7 29.2 22.0 8.5 43.6 15.8 9.2 24.4 16.2 15.3 0.3 12.5 21.4 0.7 0.9 17.0 4.2 3.0 11.6 15.2 20.0 30.0 17.7 10.5 49.8 5.9 12.2 29.9 13.4 21.7 53.0 14.8 9.6 31.9 8.0 11.7 15.5 19.6 7.9 6.5 13.2 14.1 5.2 17.9 37.0 36.2 25.7 4.0 11.1 25.2 10.2 20.5 25.2 0.0 0.2 0.1 0.0 0.4 0.0 0.4 0.2 0.2 0.6 0.0 0.1 0.1 0.2 0.3 0.1 0.0 1.3 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 4.7 0.0 2.4 2.3 0.6 2.1 1.8 1.2 1.5 1.7 1.2 0.0 3.3 0.0 4.2 4.6 1.3 8.2 0.0 0.4 5.4 1.3 2.6 1.0 1.2 44.6 0.3 0.0 6.6 3.2 5.6 3.1 1.3 11.4 1.4 1.5 5.4 0.0 0.4 4.4 2.0 2.5 3.5 0.8 1.8 3.2 0.0 1.0 0.5 0.1 4.1 1.0 0.9 0.1 1.5 0.0 11.5 0.6 15.1 0.1 1.6 2.0 6.6 0.8 2.3 62.0 80.0 6.8 0.6 1.0 3.1 1.8 8.0 1.4 EVC DWF-1 ENSG00000072840 "EvC ciliary complex subunit 1" P57679 4 5711201-5814305 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 26.4;Microglial cells: 10.3;Skeletal myocytes: 10.5" "Cancer enhanced" "Detected in all" "renal cancer: 16.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 62.3;hTERT-HME1: 60.7;hTERT-RPE1: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008703, HPA016046" Uncertain NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "HPA008703: AB_1078765, HPA016046: AB_1848299" "unprognostic (1.69e-1)" "unprognostic (5.39e-2)" "unprognostic (1.15e-1)" "unprognostic (6.58e-2)" "unprognostic (6.61e-2)" "unprognostic (9.37e-2)" "unprognostic (5.40e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-1)" "unprognostic (2.56e-2)" "unprognostic (9.63e-2)" "unprognostic (2.82e-1)" "prognostic favorable (5.60e-9)" "unprognostic (3.29e-2)" "unprognostic (1.40e-1)" "unprognostic (1.86e-2)" "prognostic unfavorable (9.47e-5)" 6.6 3.3 2.2 3.0 2.4 0.1 5.4 1.5 1.4 10.3 4.4 8.4 1.9 13.7 8.3 8.1 13.9 14.1 7.2 1.6 2.1 26.0 2.8 8.3 2.8 3.7 2.4 33.5 9.3 18.8 1.9 3.6 1.7 11.4 3.4 1.7 9.6 9.8 1.4 7.8 3.0 11.7 2.5 3.0 4.6 3.5 2.7 4.2 9.4 3.3 2.8 7.0 6.0 1.3 7.5 9.4 5.1 13.4 32.6 46.7 1.8 16.3 62.3 18.6 23.9 0.0 0.0 0.0 5.1 26.2 31.0 8.7 5.4 13.5 15.2 12.4 3.7 0.0 5.6 2.5 24.1 0.0 1.4 23.2 19.4 24.8 60.7 53.0 13.1 0.0 0.1 0.1 43.6 0.0 0.0 0.0 5.6 0.0 8.6 11.4 14.1 0.2 6.4 1.3 2.9 8.7 0.0 0.0 6.4 4.9 3.4 0.6 22.9 15.8 3.0 11.3 14.5 9.9 8.6 0.8 45.2 0.0 15.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 1.5 1.4 1.6 2.1 3.7 2.4 1.7 2.5 2.7 1.3 0.5 3.2 2.3 26.4 0.1 3.4 1.9 3.6 2.2 0.5 0.5 1.1 2.0 1.5 2.2 3.7 0.0 0.1 0.0 0.0 1.9 0.6 0.5 0.8 6.6 0.7 0.0 0.4 1.2 0.0 0.0 6.5 1.5 4.5 0.0 1.5 0.7 0.8 0.0 0.0 1.1 0.0 2.0 0.0 1.0 0.2 0.9 0.2 5.4 10.3 0.0 2.0 0.0 2.0 0.1 0.3 0.0 0.7 0.4 0.9 0.0 1.5 1.5 0.1 0.0 10.5 2.6 0.0 0.0 2.0 2.8 0.1 0.9 2.4 0.0 1.2 EVC2 LBN ENSG00000173040 "EvC ciliary complex subunit 2" Q86UK5 4 5542772-5709548 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 17.6;Basal squamous epithelial cells: 12.0;Fibroblasts: 8.9;Leydig cells: 11.5;Skeletal myocytes: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 9.7;HHSteC: 13.0;hTERT-HME1: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040910, HPA048122" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Microtubules, Cytokinetic bridge" "Nucleoplasm, Cytosol" "HPA040910: AB_2677195, HPA048122: AB_2680272" "unprognostic (6.56e-2)" "unprognostic (6.74e-2)" "unprognostic (5.10e-2)" "unprognostic (2.25e-1)" "unprognostic (8.23e-3)" "unprognostic (2.80e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (1.71e-1)" "unprognostic (1.28e-1)" "unprognostic (8.57e-2)" "unprognostic (9.37e-2)" "prognostic favorable (1.58e-4)" "unprognostic (2.51e-2)" "unprognostic (3.14e-1)" "unprognostic (5.61e-2)" "unprognostic (6.29e-5)" 4.8 0.7 1.3 1.5 1.4 0.1 3.6 1.2 1.1 6.0 2.3 3.7 0.6 4.7 1.7 2.2 4.7 2.7 3.1 1.3 1.4 2.6 0.7 2.1 1.9 1.6 1.5 7.8 1.7 3.1 1.1 1.3 1.2 3.2 0.6 0.3 2.8 2.0 1.1 3.8 2.0 2.3 1.4 1.0 2.1 1.6 1.5 1.0 3.8 1.9 1.7 4.1 4.4 1.3 0.0 2.7 0.0 6.6 8.4 9.3 0.0 4.1 9.7 3.6 6.0 0.0 0.0 5.2 0.0 3.3 2.0 2.8 0.0 1.7 3.4 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 5.9 4.6 4.6 10.6 0.0 3.9 0.0 0.0 0.2 5.3 0.0 0.0 0.0 3.9 0.0 0.0 8.6 8.2 0.0 0.4 0.0 0.4 0.6 0.0 0.0 0.0 1.6 0.0 0.5 6.7 0.0 0.0 2.4 0.0 4.1 4.7 1.2 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 1.4 1.2 1.1 1.3 1.4 1.6 1.5 1.2 1.4 1.5 1.3 0.6 0.0 0.5 17.6 0.8 2.2 4.9 2.3 12.0 0.0 0.9 2.2 1.0 1.5 1.3 0.0 0.0 8.3 1.7 0.0 0.0 1.9 2.2 0.7 5.6 1.2 0.0 0.4 0.3 0.5 0.3 8.9 0.5 1.7 2.5 4.7 1.4 0.1 0.5 0.0 0.3 0.0 0.0 0.3 1.2 0.9 11.5 0.8 0.0 6.5 0.0 1.9 1.0 1.0 0.3 0.6 0.0 7.9 1.7 2.8 0.0 0.9 1.0 0.1 0.0 14.7 3.2 1.8 2.1 4.4 0.9 1.4 2.8 3.4 0.0 1.4 EXOC6B "KIAA0919, SEC15B, SEC15L2" ENSG00000144036 "Exocyst complex component 6B" Q9Y2D4 2 72175984-72826041 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 50.7" "Cell type enhanced" "Detected in many" "Astrocytes: 210.3;Excitatory neurons: 351.1;Inhibitory neurons: 393.6;Microglial cells: 286.7;Oligodendrocyte precursor cells: 288.5;Oligodendrocytes: 863.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034546, HPA063991" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear bodies" Cytosol "HPA034546: AB_2674218, HPA063991: AB_2685168" "unprognostic (5.29e-2)" "unprognostic (1.40e-1)" "unprognostic (1.92e-1)" "unprognostic (1.18e-3)" "unprognostic (1.81e-1)" "unprognostic (7.56e-2)" "unprognostic (1.06e-2)" "unprognostic (9.34e-2)" "unprognostic (1.32e-1)" "unprognostic (2.16e-3)" "unprognostic (3.38e-2)" "unprognostic (2.61e-1)" "unprognostic (4.35e-3)" "unprognostic (4.38e-3)" "unprognostic (1.55e-1)" "unprognostic (1.18e-1)" "unprognostic (5.29e-2)" 11.3 13.4 22.3 4.2 32.7 1.2 8.6 18.8 23.9 12.6 3.2 8.6 7.3 10.1 6.0 15.1 7.8 6.5 50.7 20.7 25.7 7.2 3.8 7.2 3.1 23.9 25.7 15.0 5.0 13.2 6.1 13.0 23.3 8.0 5.7 14.1 7.7 8.9 11.1 26.5 9.1 10.0 16.4 5.2 6.9 6.9 22.2 4.4 10.2 11.5 6.4 9.7 13.0 40.9 21.7 16.3 14.7 17.8 41.2 16.9 25.3 15.6 21.9 13.2 8.6 22.3 3.3 5.6 9.5 26.2 19.6 35.4 12.4 25.7 18.9 4.2 10.1 16.7 11.0 12.8 22.2 2.4 5.5 14.6 36.6 14.9 23.1 20.6 21.8 8.7 1.8 0.0 17.6 7.5 6.4 2.9 15.3 14.9 9.0 3.4 26.4 2.3 12.7 50.1 7.3 6.3 26.7 8.2 10.9 16.1 5.7 2.3 24.3 15.2 12.8 13.1 9.6 5.5 5.9 0.0 17.7 1.2 12.4 1.3 0.5 0.0 0.7 0.4 0.5 0.7 0.5 0.4 0.4 0.7 0.6 0.9 0.0 0.5 0.6 0.1 0.8 0.4 22.3 32.7 18.8 23.9 20.7 25.7 23.9 25.7 23.3 16.4 22.2 40.9 17.8 0.0 4.1 210.3 4.1 26.1 10.2 9.8 14.8 17.4 5.2 5.2 87.1 12.8 5.1 9.2 25.0 15.1 5.0 10.2 5.9 9.3 62.9 5.6 14.5 14.1 3.0 2.1 351.1 11.5 13.2 12.4 30.5 9.2 8.2 11.6 11.4 5.6 4.6 16.8 393.6 6.0 4.1 12.0 7.1 8.2 8.4 5.0 5.4 286.7 2.0 9.9 1.0 288.5 863.3 11.0 8.6 7.5 3.7 8.1 28.2 5.5 8.4 11.1 0.0 13.5 14.7 12.0 4.9 13.1 37.4 24.6 4.7 5.5 4.5 10.7 EXOSC3 "CGI-102, hRrp-40, hRrp40p, p10, RRP40, Rrp40p" ENSG00000107371 "Exosome component 3" Q9NQT5 9 37759234-37832117 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020485 Supported Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA020485: AB_10960685" "unprognostic (7.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (3.69e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (7.01e-5)" "unprognostic (3.06e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (1.71e-3)" "unprognostic (5.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.20e-2)" "unprognostic (9.25e-3)" "unprognostic (2.07e-1)" "unprognostic (1.64e-1)" "unprognostic (1.04e-1)" 9.9 12.3 5.4 9.7 5.7 6.5 9.1 8.7 6.3 10.4 5.6 9.1 7.2 9.7 4.3 14.4 8.8 4.1 7.8 5.4 5.4 10.5 10.1 7.5 11.1 4.9 5.4 10.3 7.9 6.9 8.5 6.6 5.0 9.4 6.2 5.2 9.3 6.5 11.4 8.2 8.9 5.1 5.7 10.8 8.9 21.6 5.5 12.9 8.4 5.3 11.8 10.2 11.5 7.1 69.2 46.8 25.1 32.5 16.5 13.4 33.7 38.5 15.0 31.7 29.6 63.0 11.1 52.3 29.0 14.3 36.2 26.2 28.3 27.3 35.7 75.1 46.9 43.4 57.5 59.3 19.4 66.7 38.5 9.1 13.5 24.0 15.2 10.2 17.0 38.1 108.7 24.7 22.8 40.9 59.3 53.1 69.6 61.7 53.9 53.9 31.2 29.2 17.9 22.0 36.8 36.4 21.9 18.0 26.3 19.8 23.7 48.0 19.7 25.4 47.1 32.0 62.2 16.5 45.4 70.7 25.7 51.2 28.9 34.1 44.4 36.8 35.6 53.9 45.7 53.1 42.9 47.8 42.4 49.1 43.0 41.3 27.8 40.2 49.3 50.4 51.2 55.6 5.4 5.7 8.7 6.3 5.4 5.4 4.9 5.4 5.0 5.7 5.5 7.1 14.7 22.4 19.9 3.3 25.8 54.2 32.7 47.2 8.6 7.4 17.1 19.3 7.8 22.8 24.0 7.3 0.0 58.0 22.6 13.5 33.2 40.6 74.3 19.2 20.1 14.6 10.7 29.5 4.3 34.9 76.7 20.9 8.6 13.2 29.2 23.7 12.8 13.1 45.4 6.7 4.1 14.9 22.4 19.9 17.9 16.4 16.8 17.6 19.6 1.9 26.3 11.2 20.6 2.5 5.9 34.9 17.7 13.2 19.9 27.6 15.7 32.7 21.9 7.5 26.3 17.6 30.6 132.4 53.1 20.0 54.1 31.5 19.6 28.9 20.2 27.2 EXOSC8 "bA421P11.3, CIP3, EAP2, OIP2, p9, RRP43, Rrp43p" ENSG00000120699 "Exosome component 8" Q96B26 13 36998816-37009614 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 163.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034240, HPA039702, HPA043942, HPA075230" Uncertain Supported "Nucleoli fibrillar center,Mitotic chromosome,Vesicles" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center, Mitotic chromosome, Vesicles" "CAB034240: AB_2101977, HPA039702: AB_2676634, HPA043942: AB_2678742, HPA075230: " "unprognostic (8.67e-2)" "unprognostic (9.39e-2)" "unprognostic (5.77e-2)" "unprognostic (1.03e-1)" "unprognostic (2.58e-2)" "unprognostic (1.24e-2)" "unprognostic (1.02e-1)" "unprognostic (4.01e-2)" "unprognostic (3.24e-3)" "unprognostic (2.45e-2)" "unprognostic (2.35e-2)" "unprognostic (7.32e-3)" "prognostic unfavorable (8.39e-7)" "unprognostic (9.58e-3)" "unprognostic (7.42e-2)" "unprognostic (1.10e-1)" "unprognostic (4.51e-1)" 15.0 14.2 16.6 19.1 17.6 27.5 18.8 17.9 24.3 16.8 16.6 17.0 12.6 14.2 14.4 18.2 16.8 8.4 19.4 16.9 17.8 17.9 19.8 13.5 21.2 17.5 17.1 16.4 13.9 11.6 10.8 15.6 18.1 14.2 19.0 15.3 11.3 13.2 24.2 16.6 14.0 16.6 17.3 17.5 15.3 27.8 17.0 31.5 12.3 24.8 25.1 16.2 14.7 19.7 47.5 33.5 97.7 66.4 28.4 30.1 73.8 68.9 48.8 93.2 74.2 72.7 93.6 65.1 29.8 38.2 91.4 64.7 92.7 67.1 111.5 96.3 73.9 174.8 34.2 87.4 37.0 148.3 58.9 17.4 51.3 62.6 100.2 24.1 72.8 93.6 86.6 41.3 66.4 59.1 78.6 116.6 101.4 113.2 44.0 48.5 98.6 53.5 51.1 30.8 23.8 46.1 38.1 44.5 65.3 51.1 35.4 117.6 37.2 35.5 49.1 42.9 95.5 23.3 29.4 135.7 56.0 104.1 66.8 28.9 29.8 23.5 42.8 39.6 44.8 66.0 54.1 50.5 33.9 57.2 67.1 62.7 6.0 46.2 41.7 54.8 54.6 52.4 16.6 17.6 17.9 24.3 16.9 17.8 17.5 17.1 18.1 17.3 17.0 19.7 43.5 32.1 38.9 15.7 40.1 36.1 51.6 109.6 25.0 20.8 25.0 50.0 50.2 18.6 69.5 11.0 8.4 86.8 46.8 13.1 56.7 58.1 115.7 21.5 31.4 39.4 13.2 57.9 7.0 52.1 92.3 41.8 19.4 20.6 103.6 46.2 18.5 17.4 46.8 28.6 8.6 19.1 79.3 13.6 34.2 54.6 40.7 26.0 26.6 10.3 32.6 27.1 35.0 17.1 22.0 36.1 16.4 36.5 38.8 29.0 18.0 26.6 53.4 32.0 26.3 38.8 52.1 163.3 85.9 29.0 36.2 67.0 38.7 42.7 30.2 37.7 EXPH5 SLAC2-B ENSG00000110723 "Exophilin 5" Q8NEV8 11 108505435-108593768 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.7;skin 1: 25.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.4;Basal keratinocytes: 107.7;Glandular and luminal cells: 89.5;Respiratory ciliated cells: 98.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 15 "cerebellum: 67.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 7.9;hTERT-HME1: 11.2;RT4: 20.5;SK-BR-3: 9.7" "Group enriched" "Detected in many" 4 "cerebellum: 20.9;cerebral cortex: 6.7" "Region enriched" "Detected in many" 8 "cerebellum: 30.9" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "unprognostic (1.34e-3)" "unprognostic (8.36e-2)" "unprognostic (1.18e-1)" "prognostic favorable (3.42e-6)" "unprognostic (2.91e-1)" "prognostic favorable (1.46e-4)" "unprognostic (4.57e-3)" "prognostic favorable (5.12e-4)" "unprognostic (1.26e-1)" "unprognostic (3.03e-1)" "unprognostic (5.56e-3)" "unprognostic (1.33e-1)" "prognostic favorable (2.43e-4)" "unprognostic (1.18e-2)" "unprognostic (2.57e-1)" "unprognostic (3.36e-1)" "unprognostic (4.51e-1)" 0.4 0.1 1.3 0.5 2.5 0.2 2.9 67.7 2.3 2.2 12.8 3.9 0.7 0.7 2.7 7.4 1.7 0.3 0.2 2.1 1.9 2.4 7.7 3.9 0.1 1.5 3.6 0.3 1.0 4.7 0.5 2.8 4.6 1.5 4.4 0.3 4.4 0.3 0.1 25.8 0.8 0.4 1.1 0.2 3.2 0.7 1.7 0.8 1.0 0.2 1.4 0.7 3.8 3.4 3.9 0.4 0.2 0.1 0.0 0.1 3.2 0.2 0.1 0.0 0.6 1.0 5.9 0.0 0.2 0.2 0.9 7.9 5.7 2.1 0.2 0.1 1.7 1.6 0.8 0.0 0.5 0.8 0.1 0.1 3.3 0.0 11.2 0.5 0.0 1.3 3.0 0.0 3.1 0.6 1.0 0.0 0.2 6.4 2.4 0.0 0.1 0.0 0.6 20.5 1.4 0.8 1.0 9.7 0.2 1.1 6.4 0.1 0.1 0.0 2.3 0.0 1.1 0.1 0.0 0.0 0.1 0.4 0.0 0.8 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.1 0.1 0.1 0.5 0.5 0.8 0.9 0.1 0.2 0.0 0.1 1.3 2.5 67.7 2.3 2.1 1.9 1.5 3.6 4.6 1.1 1.7 3.4 0.6 147.4 60.0 18.6 0.9 107.7 12.9 16.6 58.6 0.6 14.1 8.6 5.7 4.3 65.3 20.2 14.6 44.5 2.4 47.9 3.9 5.4 10.3 74.8 7.8 2.5 4.9 3.2 9.0 4.9 4.9 5.6 20.9 89.5 1.3 0.9 0.7 24.2 3.8 0.0 4.9 38.6 14.2 0.6 15.2 2.3 0.6 1.8 5.4 16.9 1.3 0.5 1.0 3.0 0.6 3.6 17.5 0.0 1.5 30.4 1.9 3.7 98.5 1.4 0.0 0.3 2.1 1.1 0.5 46.9 72.2 54.6 2.8 0.4 29.1 19.3 EXT1 "LGCR, LGS, ttv" ENSG00000182197 "Exostosin glycosyltransferase 1" Q16394 8 117794490-118111826 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Hereditary multiple exostoses, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 229.6;Inhibitory neurons: 421.4;Microglial cells: 144.3;Oligodendrocyte precursor cells: 162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 95.5;fHDF/TERT166: 82.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044394 Uncertain NA Yes 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA044394: AB_10963838" "unprognostic (1.29e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (2.73e-2)" "unprognostic (2.02e-3)" "unprognostic (2.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.70e-1)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (6.58e-2)" "unprognostic (1.27e-2)" "unprognostic (9.84e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.85e-1)" 5.1 4.2 2.0 5.2 2.5 1.1 4.3 2.3 2.3 7.6 3.9 7.7 14.1 4.9 2.9 5.5 3.8 5.8 7.0 3.4 1.3 3.8 13.3 7.9 3.0 1.1 2.1 5.0 5.5 3.3 1.8 11.1 1.0 5.0 8.2 2.7 3.2 7.7 1.5 7.8 11.7 6.1 1.4 5.1 5.3 2.4 1.2 3.0 5.2 2.4 3.8 11.8 4.2 1.9 29.3 8.5 13.5 5.5 22.8 23.0 5.9 51.5 95.5 40.9 39.4 10.0 3.1 0.5 24.8 82.1 24.0 19.8 5.0 31.4 55.7 12.5 9.9 1.5 5.9 6.5 10.0 0.0 1.6 10.8 10.8 38.8 38.5 47.7 28.1 2.9 0.9 7.4 18.7 3.2 1.8 0.2 4.6 13.7 10.1 0.0 4.1 1.3 23.1 7.6 4.5 4.0 8.0 3.9 9.2 32.6 5.3 0.5 32.0 35.2 28.7 32.0 15.8 5.5 5.1 2.4 36.5 0.0 9.2 0.1 0.4 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.3 0.1 2.0 2.5 2.3 2.3 3.4 1.3 1.1 2.1 1.0 1.4 1.2 1.9 21.1 19.2 6.0 127.3 3.0 54.8 23.0 27.7 10.2 23.6 7.8 10.8 6.5 24.3 13.7 7.3 14.6 6.5 5.1 49.2 0.0 37.3 1.8 17.7 37.1 25.9 4.8 1.7 229.6 20.1 3.9 32.6 11.7 18.2 7.0 108.3 16.8 32.9 2.5 10.1 421.4 25.5 4.1 37.9 13.9 2.7 17.4 9.6 19.6 144.3 8.1 5.9 4.1 162.8 101.8 27.4 16.1 36.1 5.3 19.3 44.9 4.9 14.2 22.4 0.0 17.1 36.4 0.6 5.1 12.6 47.3 12.2 4.2 35.0 26.3 26.8 EXT2 SOTV ENSG00000151348 "Exostosin glycosyltransferase 2" Q93063 11 44095673-44251962 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, Hereditary multiple exostoses, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078409 Supported "Golgi apparatus" NA NA 39000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA078409: AB_2686884" "unprognostic (5.87e-2)" "unprognostic (3.05e-3)" "unprognostic (3.48e-2)" "unprognostic (3.94e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.77e-3)" "unprognostic (2.22e-2)" "unprognostic (1.97e-1)" "unprognostic (2.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.70e-2)" "prognostic unfavorable (5.36e-6)" "unprognostic (7.07e-3)" "unprognostic (2.97e-1)" "unprognostic (3.85e-1)" "unprognostic (1.36e-2)" 33.5 22.8 14.4 22.1 15.4 11.2 29.3 15.4 16.3 36.1 17.5 29.1 26.5 43.1 33.3 20.1 33.7 28.1 27.3 15.6 18.1 26.5 26.9 27.9 16.0 15.5 16.0 33.5 26.5 28.9 20.1 61.9 15.5 29.8 28.7 20.9 26.7 30.2 16.2 25.8 31.0 49.3 14.7 21.6 23.8 21.6 19.4 15.2 27.6 18.4 17.3 29.7 28.5 16.1 57.9 71.6 38.3 121.5 170.4 124.2 60.8 181.1 198.0 93.1 125.1 51.2 36.5 40.4 82.1 188.8 98.5 90.0 41.0 114.0 110.0 83.2 71.5 38.4 33.7 39.7 67.5 37.5 76.6 97.7 73.4 56.3 86.6 108.8 132.7 34.8 50.0 63.9 68.4 40.3 25.9 22.3 43.8 67.1 70.9 32.3 116.1 21.1 53.9 49.1 30.9 35.5 118.1 41.4 28.1 67.0 69.8 37.2 137.8 127.4 90.6 133.1 111.4 33.4 46.0 30.4 84.7 27.9 140.0 15.2 17.5 19.4 20.9 17.7 23.5 9.0 16.5 19.3 21.3 8.8 15.4 15.2 3.4 26.3 12.8 7.4 14.2 15.5 14.4 15.4 15.4 16.3 15.6 18.1 15.5 16.0 15.5 14.7 19.4 16.1 24.5 16.0 10.6 41.4 8.7 15.2 17.3 22.0 10.8 11.5 11.0 11.4 10.2 8.6 13.5 12.9 14.6 34.3 10.6 21.1 5.9 33.5 43.2 7.9 17.1 19.2 1.8 6.7 64.3 23.7 37.0 32.3 7.7 11.5 6.3 22.7 22.9 18.3 18.3 13.5 63.3 12.9 12.2 10.8 7.2 23.0 27.4 10.4 5.4 28.1 10.2 17.4 7.2 50.3 51.8 24.0 14.9 28.6 7.0 23.6 31.6 8.2 8.1 15.0 19.7 15.8 20.7 51.2 24.4 10.2 12.6 35.3 9.2 12.2 15.0 15.3 EXTL3 "botv, REGR" ENSG00000012232 "Exostosin like glycosyltransferase 3" O43909 8 28600469-28755599 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025387 Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 38: Heart - Muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "CAB025387: " "unprognostic (1.35e-1)" "unprognostic (1.31e-1)" "unprognostic (5.53e-2)" "unprognostic (1.19e-3)" "unprognostic (9.83e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (4.25e-2)" "unprognostic (9.29e-3)" "unprognostic (1.05e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-3)" "prognostic favorable (2.47e-5)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (8.91e-2)" "unprognostic (1.39e-2)" 10.8 16.5 11.3 7.2 12.0 3.8 6.3 7.6 13.7 8.9 5.8 11.1 5.5 13.8 5.4 12.3 11.3 7.9 31.1 14.7 10.4 7.0 6.2 8.6 5.4 10.7 14.3 10.0 11.9 18.9 10.3 13.8 7.2 8.5 5.4 11.2 8.1 11.8 20.8 11.1 6.7 17.9 8.9 8.6 9.0 10.3 23.4 6.4 7.7 22.7 4.8 10.6 7.2 12.7 45.3 33.6 70.1 37.0 18.8 18.5 15.6 33.7 32.6 20.3 16.4 28.9 15.9 12.2 46.6 40.1 28.2 29.7 34.5 55.1 22.4 8.9 18.9 17.2 15.7 14.3 9.8 8.6 46.9 22.2 36.7 15.9 14.6 16.9 44.3 17.4 16.2 15.4 16.5 8.5 15.5 4.7 49.2 13.3 13.6 18.4 31.3 7.1 31.2 29.0 15.2 26.6 14.3 8.6 17.3 22.0 8.4 9.4 34.9 26.6 62.7 25.4 28.9 7.9 17.9 13.5 22.5 10.3 23.7 3.0 1.3 2.0 1.7 0.9 0.8 0.3 0.7 0.9 1.3 0.4 0.5 0.4 5.7 0.5 1.4 1.1 0.3 0.8 11.3 12.0 7.6 13.7 14.7 10.4 10.7 14.3 7.2 8.9 23.4 12.7 6.3 3.2 4.4 10.4 2.4 5.0 2.9 8.7 6.8 17.5 4.8 4.2 26.8 7.2 5.0 1.8 25.0 3.7 7.1 4.9 3.9 9.7 32.0 4.2 7.0 7.3 4.2 1.3 20.0 10.6 16.9 6.5 4.1 5.9 5.7 3.0 8.2 9.0 4.4 8.4 19.0 2.4 2.0 6.6 2.5 10.1 9.9 6.1 5.4 16.9 5.7 6.7 23.7 13.0 16.6 12.3 2.4 14.3 4.2 6.3 2.1 3.5 4.9 16.2 26.3 8.4 9.6 4.3 9.1 4.3 3.0 2.2 4.5 8.6 3.1 3.1 EYA1 BOR ENSG00000104313 "EYA transcriptional coactivator and phosphatase 1" Q99502 8 71197433-71592025 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 18.7;parathyroid gland: 23.7" "Cell type enriched" "Detected in some" 11 "Astrocytes: 214.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 27.6;RH-30: 21.3;RPMI-8226: 9.5;SH-SY5Y: 51.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 20.7" HPA028917 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear bodies" "HPA028917: AB_2672826" "unprognostic (3.74e-2)" "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.72e-3)" "unprognostic (5.95e-2)" "unprognostic (9.17e-2)" "unprognostic (2.91e-4)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (1.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.13e-1)" "unprognostic (4.22e-12)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (3.81e-4)" "unprognostic (1.25e-2)" 0.6 0.6 2.8 0.1 7.8 0.0 0.2 0.5 2.1 5.1 18.7 0.1 0.1 0.1 0.1 0.4 2.0 0.3 4.5 1.3 2.5 0.1 0.0 0.4 0.0 2.1 4.9 0.2 0.0 23.7 10.8 0.0 2.3 12.0 0.2 0.4 0.8 4.0 2.8 0.0 0.2 0.2 0.0 0.1 0.8 0.8 4.6 11.7 0.6 2.5 0.1 2.6 4.3 0.6 0.2 0.0 6.4 27.6 0.0 0.0 0.0 0.2 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.9 1.6 0.0 0.0 4.7 0.0 2.2 0.0 0.0 0.5 0.0 6.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 1.0 0.0 0.0 0.0 2.0 0.0 1.5 0.0 21.3 9.5 0.0 0.0 2.2 51.4 0.0 0.0 1.6 5.9 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 6.3 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 7.8 0.5 2.1 1.3 2.5 2.1 4.9 2.3 0.0 4.6 0.6 0.2 0.0 0.0 214.5 0.0 0.1 0.0 6.4 0.6 0.1 0.0 0.1 8.8 0.0 7.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 4.4 3.1 0.1 0.2 0.0 0.0 1.3 0.0 0.5 1.3 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 13.5 0.0 2.0 0.0 0.0 6.4 0.3 0.0 0.0 11.2 0.0 0.1 0.0 18.6 0.6 0.0 0.0 0.4 0.0 0.1 0.0 0.3 10.5 0.2 0.0 0.2 0.5 0.8 1.0 1.1 0.1 0.5 0.0 1.4 0.0 0.1 EZH2 "ENX-1, EZH1, KMT6, KMT6A" ENSG00000106462 "Enhancer of zeste 2 polycomb repressive complex 2 subunit" Q15910 7 148807383-148884321 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.9;lymphoid tissue: 43.0;testis: 27.8" "Cell type enhanced" "Detected in many" "Early spermatids: 109.3;Spermatocytes: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009589, HPA029131" Enhanced Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB009589: , HPA029131: AB_2672920" "unprognostic (2.42e-1)" "unprognostic (3.95e-3)" "unprognostic (1.57e-1)" "unprognostic (3.30e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "prognostic unfavorable (2.11e-6)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.32e-3)" "unprognostic (1.58e-3)" "unprognostic (1.69e-3)" "prognostic unfavorable (8.18e-12)" "prognostic favorable (6.97e-4)" "unprognostic (1.83e-1)" "unprognostic (2.12e-1)" "unprognostic (6.67e-2)" 1.5 1.5 1.1 10.1 1.1 47.9 2.7 2.0 1.3 2.7 1.5 7.0 6.4 2.0 1.2 10.8 1.1 1.9 1.2 1.1 1.1 2.1 3.3 2.3 22.1 1.2 1.2 1.6 3.7 1.3 0.5 4.8 1.2 1.3 8.2 3.3 2.8 0.2 2.9 10.7 6.9 2.8 1.0 5.6 4.0 27.8 1.5 43.0 1.3 1.9 21.1 3.5 3.8 1.2 65.6 30.1 99.7 66.9 3.1 5.1 54.6 49.7 19.9 39.9 40.2 45.6 73.2 114.3 23.5 18.7 36.3 39.0 52.1 17.1 50.6 164.9 51.8 48.9 38.4 35.5 8.0 110.1 38.5 4.3 9.6 29.9 15.9 12.1 24.0 108.9 105.9 73.6 36.2 74.0 215.7 91.7 79.6 57.0 39.9 131.3 56.0 70.9 18.6 31.0 95.1 60.3 62.3 46.8 16.5 25.3 34.3 46.7 14.8 42.4 19.8 85.2 90.4 65.7 76.6 115.3 38.6 74.2 84.9 0.4 1.7 1.1 1.2 1.2 0.9 1.1 2.6 2.2 3.8 0.6 1.4 0.9 0.1 7.2 3.6 0.8 8.3 1.2 1.1 1.1 2.0 1.3 1.1 1.1 1.2 1.2 1.2 1.0 1.5 1.2 14.4 0.0 6.7 1.3 14.5 26.5 6.7 6.3 10.2 6.0 15.1 12.2 6.1 2.8 7.1 7.3 35.5 28.8 35.9 14.7 3.9 9.5 109.3 16.3 17.0 9.4 9.0 57.0 6.2 8.5 32.2 9.9 15.8 24.2 21.6 45.9 3.3 2.2 11.9 15.2 9.2 20.5 6.1 9.0 33.6 27.7 3.1 19.1 14.2 14.0 14.9 2.6 12.3 16.6 7.0 12.4 10.5 0.7 37.4 4.8 6.8 1.2 9.7 21.3 6.6 13.8 24.1 142.2 58.2 35.8 29.0 30.5 25.7 4.7 22.1 5.9 FAM111A "FLJ22794, KIAA1895" ENSG00000166801 "Family with sequence similarity 111 member A" Q96PZ2 11 59142748-59155039 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction" "DNA-binding, Hydrolase, Protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039529, HPA040176" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli fibrillar center" "HPA039529: AB_10795149, HPA040176: AB_10793958" "unprognostic (4.12e-3)" "unprognostic (8.47e-2)" "unprognostic (7.80e-3)" "unprognostic (1.00e-1)" "unprognostic (1.81e-1)" "unprognostic (2.41e-1)" "unprognostic (5.83e-3)" "unprognostic (1.81e-1)" "unprognostic (9.88e-2)" "unprognostic (5.96e-2)" "unprognostic (2.74e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (1.15e-5)" "unprognostic (2.66e-2)" "unprognostic (1.79e-1)" "unprognostic (1.76e-2)" "prognostic favorable (4.39e-4)" 14.8 18.9 7.0 23.1 7.0 20.3 16.0 6.7 9.6 20.8 12.9 17.1 22.5 13.8 17.3 12.8 16.5 18.7 11.6 6.6 7.6 23.7 17.9 25.2 36.1 9.0 7.7 14.6 15.0 16.9 14.3 19.5 8.1 33.2 19.3 9.1 19.0 10.7 5.5 18.8 27.6 10.9 7.8 42.5 22.5 7.1 8.2 42.3 26.6 4.1 30.1 14.8 17.4 8.4 66.0 16.2 7.9 7.5 16.9 21.4 5.1 91.6 50.8 38.5 56.3 24.9 59.0 94.3 37.1 29.7 51.2 21.9 26.9 40.4 47.4 86.0 1.2 36.3 22.7 7.6 17.8 58.7 45.7 14.5 9.6 36.2 11.1 22.0 37.7 57.2 4.8 76.7 42.2 18.0 85.6 36.9 3.5 19.5 17.5 59.9 28.7 22.8 25.4 57.6 0.2 2.3 48.6 38.5 17.5 4.1 80.1 24.7 37.0 61.9 55.5 42.5 42.7 39.0 43.4 15.3 34.3 39.5 75.9 6.0 5.0 4.8 4.2 3.4 5.3 2.6 2.7 3.2 4.6 2.6 2.4 2.5 5.4 5.0 1.9 1.2 3.1 2.2 7.0 7.0 6.7 9.6 6.6 7.6 9.0 7.7 8.1 7.8 8.2 8.4 38.9 64.1 43.7 14.4 27.4 8.5 10.7 21.3 26.2 1.7 24.2 24.3 5.5 14.3 24.7 16.5 0.0 11.1 40.5 20.8 9.8 13.8 0.2 31.5 26.0 25.9 6.0 42.5 0.2 7.7 1.4 22.7 30.5 20.7 27.8 83.9 30.0 8.1 28.2 0.0 0.2 24.8 22.4 31.3 19.5 1.8 13.1 39.2 7.2 21.5 40.2 25.2 47.4 12.1 3.9 7.5 17.6 6.8 29.7 14.2 19.4 10.3 36.9 7.3 0.0 17.0 14.3 0.4 2.1 24.3 8.8 4.4 41.3 48.8 18.6 14.0 FAM111B CANP ENSG00000189057 "Family with sequence similarity 111 member B" Q6SJ93 11 59107185-59127412 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.0" "Cell type enhanced" "Detected in many" "B-cells: 12.8;Erythroid cells: 9.1;Plasma cells: 8.8;Squamous epithelial cells: 7.1;Undifferentiated cells: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.3;naive B-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038637 Uncertain Approved Nucleoplasm,Cytosol No Yes "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Cytosol "HPA038637: AB_10672522" "unprognostic (2.31e-1)" "unprognostic (2.68e-2)" "unprognostic (1.80e-3)" "unprognostic (6.94e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.49e-3)" "unprognostic (1.40e-2)" "unprognostic (4.85e-2)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.01e-2)" "unprognostic (1.24e-5)" "unprognostic (2.94e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-3)" "unprognostic (1.24e-1)" 0.9 0.5 0.5 5.9 0.6 4.8 2.7 2.8 1.8 1.0 0.1 5.6 3.4 1.0 0.5 3.4 0.5 0.8 0.3 0.6 1.1 0.4 2.5 1.1 12.3 0.5 1.0 0.2 0.6 0.9 0.0 1.7 0.7 1.0 5.8 1.3 0.8 0.4 0.4 4.4 4.0 2.0 0.1 1.8 3.2 0.8 0.6 18.0 0.9 0.1 13.3 1.7 1.0 2.1 72.6 18.5 26.6 0.4 2.7 4.9 0.3 53.5 26.7 31.2 46.1 38.7 28.0 89.8 35.4 15.7 26.3 54.7 39.5 36.2 55.2 46.8 9.5 9.8 32.3 16.9 0.1 0.3 11.1 1.2 1.2 30.3 2.4 6.0 16.9 24.1 2.8 81.9 37.2 27.3 57.7 0.6 0.3 43.2 21.0 60.1 39.7 34.7 16.8 61.2 5.2 16.9 44.4 50.8 8.7 9.7 56.2 5.0 9.4 24.1 52.4 73.5 49.6 62.6 48.4 0.6 35.0 0.4 35.4 0.2 0.1 0.1 0.1 0.0 0.1 3.3 0.2 0.3 0.1 2.6 0.1 0.1 1.6 0.0 0.1 0.1 0.7 0.1 0.5 0.6 2.8 1.8 0.6 1.1 0.5 1.0 0.7 0.1 0.6 2.1 0.7 0.0 0.0 0.0 12.8 4.2 2.2 4.2 1.8 0.0 2.5 4.2 0.3 0.0 1.4 0.0 0.0 1.1 1.4 4.0 0.0 0.8 0.0 0.9 1.6 1.2 0.0 9.1 0.0 0.0 0.4 1.5 3.6 1.9 0.0 6.3 0.0 0.2 3.9 0.0 0.0 4.4 2.0 0.3 1.6 0.0 0.0 2.4 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.6 1.3 0.0 8.8 0.7 0.5 0.1 1.6 0.0 0.0 1.3 1.8 0.1 1.0 7.1 2.7 0.1 3.2 1.1 10.4 1.6 FAM149B1 KIAA0974 ENSG00000138286 "Family with sequence similarity 149 member B1" Q96BN6 10 73168119-73244504 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039189, HPA039859" Uncertain Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA039189: AB_10805355, HPA039859: AB_2676712" "unprognostic (2.23e-1)" "unprognostic (7.04e-2)" "unprognostic (1.52e-1)" "unprognostic (4.88e-2)" "unprognostic (6.21e-2)" "unprognostic (1.45e-1)" "unprognostic (2.34e-1)" "unprognostic (4.66e-2)" "unprognostic (3.01e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (5.13e-2)" "unprognostic (1.96e-3)" "unprognostic (1.22e-1)" "unprognostic (9.21e-3)" "unprognostic (2.68e-1)" "unprognostic (5.24e-2)" 12.3 10.6 20.7 6.4 23.1 5.2 12.4 22.8 22.9 14.1 18.9 9.2 7.7 11.5 12.6 11.7 13.6 12.6 12.6 19.2 21.3 21.8 19.1 10.4 9.4 21.6 22.1 15.0 12.2 13.9 6.2 13.3 22.8 10.9 9.9 11.8 11.3 10.6 13.6 7.8 8.9 11.5 21.1 8.0 9.9 21.9 21.3 12.4 12.3 17.2 9.7 10.6 7.6 25.3 8.7 8.4 19.8 19.0 45.9 28.5 13.9 12.5 28.6 9.8 17.1 2.5 23.6 8.1 5.8 25.8 10.8 10.1 12.6 18.4 11.7 11.1 4.7 6.3 5.6 7.4 23.8 10.2 6.1 24.6 13.4 12.6 48.6 44.5 24.9 11.7 5.8 15.2 18.0 10.4 7.7 12.9 8.7 29.8 19.7 4.3 11.2 9.9 26.4 12.1 3.3 20.1 11.1 30.1 19.6 17.8 18.6 9.9 12.7 8.2 6.6 8.2 12.6 20.0 8.8 4.4 15.9 11.3 7.0 0.7 0.2 0.6 0.3 0.6 0.2 0.3 0.1 0.2 0.4 0.4 0.5 0.4 0.5 1.0 0.2 0.6 0.1 0.1 20.7 23.1 22.8 22.9 19.2 21.3 21.6 22.1 22.8 21.1 21.3 25.3 5.4 3.2 3.1 24.8 3.9 2.0 3.5 4.6 6.8 6.7 5.3 5.2 12.2 5.7 5.4 1.8 6.2 7.4 2.4 4.6 1.9 3.9 21.8 6.1 7.0 6.2 7.7 3.0 19.7 3.6 5.8 7.2 5.1 6.1 2.5 8.2 7.1 4.0 5.4 3.3 24.9 5.0 6.1 6.3 3.1 27.6 8.4 4.0 1.8 12.2 4.1 4.6 1.0 23.6 41.3 4.2 2.2 4.5 1.8 4.6 6.6 6.9 9.8 11.4 13.1 5.9 5.0 13.4 5.1 5.3 3.7 8.2 3.4 7.2 5.4 4.3 FAM20C "DKFZp547D065, DMP4, G-CK, IMAGE:4942737" ENSG00000177706 "FAM20C golgi associated secretory pathway kinase" Q8IXL6 7 192571-260772 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" Biomineralization "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 55.2;Hepatocytes: 94.0;Hofbauer cells: 54.9;Peritubular cells: 56.4;Proximal tubular cells: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 55.3;hTERT-RPE1: 39.9;U-87 MG: 36.0;WM-115: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019823 Approved "Nucleoplasm,Golgi apparatus" "Secreted in other tissues" NA NA 240000000 "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Nucleoplasm "HPA019823: AB_1848389" "unprognostic (1.94e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (3.15e-2)" "unprognostic (1.03e-2)" "unprognostic (3.33e-3)" "unprognostic (2.47e-2)" "unprognostic (7.86e-2)" "unprognostic (2.45e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (9.40e-6)" "unprognostic (1.97e-3)" "unprognostic (2.49e-1)" "unprognostic (3.08e-3)" "unprognostic (1.94e-2)" "unprognostic (3.92e-2)" "unprognostic (2.16e-2)" "unprognostic (3.83e-3)" 32.5 14.8 7.0 7.3 5.7 1.5 32.8 5.0 7.0 19.4 0.8 44.3 4.5 19.4 2.1 14.3 20.2 5.9 30.2 4.3 5.0 34.9 56.5 27.9 1.1 12.5 9.7 20.3 13.4 1.6 18.3 2.6 6.7 29.9 1.4 1.1 20.3 3.6 30.7 14.7 23.3 6.8 6.4 8.9 38.9 7.8 12.6 0.6 19.6 6.3 0.6 36.8 15.1 6.2 19.6 6.4 0.3 10.3 11.8 20.3 0.0 17.4 23.2 7.9 5.9 0.9 10.1 0.0 9.3 21.8 10.4 14.9 1.1 0.6 1.6 4.5 0.6 0.0 3.1 3.4 8.8 0.0 1.0 55.3 1.6 0.3 0.7 39.9 5.0 0.0 0.0 0.0 1.8 1.9 0.0 0.7 8.9 0.1 0.3 2.3 0.5 0.0 4.9 0.0 4.4 0.2 17.2 0.0 2.3 1.1 9.7 6.5 14.6 10.3 5.3 7.7 5.3 0.0 0.0 0.0 36.0 1.0 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 5.7 5.0 7.0 4.3 5.0 12.5 9.7 6.7 6.4 12.6 6.2 5.0 6.4 5.1 11.8 1.2 10.1 2.3 4.5 1.8 26.9 27.6 18.7 9.9 21.5 1.0 55.2 0.0 0.5 4.6 3.4 5.9 1.8 0.0 4.1 19.0 4.5 11.9 0.4 7.4 4.8 0.5 22.6 13.7 9.5 3.8 3.1 9.3 94.0 54.9 1.7 17.0 5.3 2.0 24.4 9.8 2.6 16.1 34.5 1.8 5.6 10.8 17.1 0.0 8.5 15.3 6.3 3.7 56.4 0.1 6.6 33.7 48.7 3.4 9.0 13.1 8.7 17.3 0.3 1.0 3.5 8.1 0.5 0.9 0.6 9.0 1.9 FAR1 "FLJ22728, MLSTD2, SDR10E1" ENSG00000197601 "Fatty acyl-CoA reductase 1" Q8WVX9 11 13668668-13732346 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Cataract, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 437.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017322 Approved Supported Peroxisomes NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 15: RT4 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Peroxisomes "HPA017322: AB_1848424" "unprognostic (3.96e-2)" "unprognostic (1.92e-1)" "prognostic favorable (2.27e-4)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (4.62e-2)" "unprognostic (3.66e-1)" "unprognostic (3.30e-1)" "unprognostic (2.79e-1)" "unprognostic (3.60e-2)" "unprognostic (2.59e-2)" "unprognostic (1.84e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-1)" "unprognostic (2.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-3)" 21.1 16.2 19.3 23.0 36.0 74.9 20.6 34.3 31.5 23.8 24.5 32.9 38.7 24.7 24.9 50.9 17.7 13.7 20.0 22.6 29.7 14.0 5.0 20.2 20.5 48.4 29.9 19.9 21.3 29.1 15.6 24.6 44.1 20.5 37.6 32.6 18.2 15.4 15.2 12.2 21.1 30.7 37.3 20.5 62.0 20.8 32.1 16.5 19.8 18.6 23.9 28.4 30.0 94.8 79.5 50.6 49.1 38.4 45.9 52.6 26.7 69.2 27.6 50.0 52.7 53.5 66.4 100.9 30.2 55.5 74.3 84.3 73.2 69.9 76.1 30.0 59.4 43.4 44.8 0.2 44.1 87.9 33.7 40.2 70.3 36.2 107.7 36.9 49.6 50.2 68.9 29.3 41.5 39.9 65.5 26.3 25.8 100.1 72.6 56.9 62.6 28.4 48.4 126.4 37.7 27.3 65.5 61.6 34.4 56.2 37.8 54.1 62.1 68.5 58.2 63.7 58.4 16.4 59.6 84.7 43.4 26.4 42.4 10.4 24.9 28.0 7.7 21.3 5.4 3.5 3.7 6.6 28.5 5.5 3.3 5.5 38.9 9.1 18.2 4.4 5.3 7.7 19.3 36.0 34.3 31.5 22.6 29.7 48.4 29.9 44.1 37.3 32.1 94.8 38.6 35.3 21.1 80.0 24.2 32.2 24.2 21.5 41.5 46.0 27.6 20.3 24.1 5.7 26.2 22.0 41.7 25.7 40.2 59.8 5.9 12.8 100.8 21.1 36.5 31.4 36.0 38.5 146.0 25.9 18.5 26.8 114.7 26.2 38.7 23.3 29.6 2.5 33.9 47.1 113.5 28.8 26.4 53.5 57.0 181.3 26.8 48.8 35.6 71.2 54.8 20.6 20.6 93.5 437.2 29.3 43.4 25.6 36.1 30.8 23.3 8.7 18.7 50.4 26.3 29.3 29.3 41.6 32.3 116.9 19.9 9.9 25.8 17.0 47.7 42.0 FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Endothelial cells: 18.0;Fibroblasts: 17.9;Hepatic stellate cells: 33.2;Inhibitory neurons: 35.0;Microglial cells: 23.4;Oligodendrocytes: 54.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 11.2;fHDF/TERT166: 11.4;HSkMC: 13.6;HUVEC TERT2: 14.3;TIME: 21.9" "Low region specificity" "Detected in many" HPA052819 Approved Approved Cytosol NA NA 2300000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA052819: AB_2681963" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (7.99e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (2.81e-4)" "unprognostic (6.17e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.89e-4)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-3)" 3.3 1.0 3.2 1.4 4.1 0.0 2.7 1.2 2.7 4.0 0.7 6.4 0.9 3.0 1.3 2.3 1.9 4.3 4.0 3.8 2.0 2.8 2.5 4.5 0.8 3.1 2.8 4.9 0.9 3.0 0.6 2.9 2.8 3.7 2.3 0.5 1.0 2.6 1.6 1.4 2.2 3.5 3.5 2.7 2.0 0.7 3.3 1.1 4.0 4.8 0.8 2.5 1.8 4.8 0.0 0.9 7.4 0.8 15.5 11.2 0.0 2.6 3.0 1.2 1.2 0.0 0.4 0.0 3.1 11.4 1.5 0.0 2.8 3.2 0.7 0.0 1.3 1.7 3.3 0.1 5.4 1.1 0.0 13.6 1.9 0.7 7.0 9.1 14.3 0.0 0.0 1.9 6.7 0.1 0.5 0.0 0.5 0.0 0.3 0.9 1.5 0.0 0.1 0.0 0.2 1.5 0.4 0.0 0.0 0.4 0.0 0.0 21.9 7.8 2.2 2.7 1.1 0.3 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 4.1 1.2 2.7 3.8 2.0 3.1 2.8 2.8 3.5 3.3 4.8 19.3 6.4 0.0 8.8 0.0 1.7 0.2 1.5 0.0 3.7 0.3 1.3 6.9 0.0 0.3 5.5 0.0 0.1 0.9 0.0 0.0 0.7 0.9 0.6 8.8 18.0 0.0 0.0 9.4 0.2 0.0 17.9 1.1 1.0 0.0 1.2 33.2 7.4 0.2 0.0 35.0 0.0 0.0 2.2 2.2 0.2 5.9 0.3 3.6 23.4 0.0 1.1 1.0 6.0 54.4 0.3 0.0 4.9 1.4 0.4 0.0 0.7 0.1 0.2 0.0 5.3 4.1 0.1 0.6 0.5 0.6 0.0 0.3 5.7 0.0 0.1 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Fibroblasts: 209.4;Leydig cells: 626.6;Peritubular cells: 794.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "ASC diff: 457.1;ASC TERT1: 234.6;BJ: 202.0;BJ hTERT+: 202.5;fHDF/TERT166: 394.6;HSkMC: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" 182.2 73.4 10.7 17.7 12.8 7.5 110.4 7.4 12.5 124.9 15.7 80.3 19.1 178.4 40.0 26.8 143.0 130.2 211.1 9.4 8.6 108.4 29.3 164.8 25.5 15.5 10.9 107.3 46.4 16.8 14.5 67.0 14.2 49.0 20.6 0.6 55.8 70.9 30.4 66.9 52.7 88.7 13.1 130.9 68.9 35.6 12.7 21.8 79.5 36.0 15.7 117.5 93.3 7.5 0.0 1.6 0.2 0.0 457.1 234.6 22.5 202.0 202.5 5.8 4.5 4.7 0.0 0.0 4.2 394.6 0.6 0.1 9.8 1.0 1.0 0.0 2.3 0.4 4.7 0.0 74.2 0.0 0.1 216.6 0.4 3.9 14.1 2.8 10.4 0.1 0.0 0.1 25.3 0.4 0.5 0.5 0.5 0.0 0.5 0.4 30.2 0.2 1.2 0.1 0.2 0.1 12.3 0.7 2.6 7.0 2.9 0.3 1.9 3.2 6.6 3.8 0.1 0.1 0.0 0.2 0.4 0.0 0.0 6.6 0.1 2.2 0.8 0.2 0.5 0.0 0.3 0.1 0.0 0.1 1.1 1.8 2.5 0.0 0.2 0.0 0.1 0.4 10.7 12.8 7.4 12.5 9.4 8.6 15.5 10.9 14.2 13.1 12.7 7.5 31.4 83.3 13.1 0.0 2.1 9.2 2.4 7.1 1.8 0.0 11.2 9.3 5.2 0.0 11.5 5.5 0.0 2.5 2.5 0.1 5.9 4.7 5.9 13.3 67.4 15.2 0.0 0.4 2.6 4.7 2.5 209.4 2.0 12.0 2.5 1.8 34.2 0.4 7.8 0.0 3.6 0.1 18.3 2.5 18.4 27.5 626.6 5.8 21.4 15.9 1.6 0.0 8.2 5.0 2.3 2.2 0.0 794.8 0.7 1.3 0.0 32.5 21.4 0.0 6.6 28.0 14.5 3.0 2.8 1.3 8.7 3.7 15.5 3.5 0.4 1.2 FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.9;placenta: 76.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 132.4;Fibroblasts: 388.5;Leydig cells: 236.1;Oligodendrocytes: 218.7;Peritubular cells: 227.2;Skeletal myocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 215.1;ASC TERT1: 460.7;fHDF/TERT166: 420.8;HSkMC: 251.3;hTERT-RPE1: 211.1;U-138 MG: 206.9;U-2197: 305.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188" Enhanced Approved Cytosol "Secreted to blood" NA NA 520000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB002670: , CAB058696: AB_2665596, CAB068188: AB_2665597, HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.44e-5)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavorable (5.11e-4)" 60.9 4.4 1.4 14.5 5.4 3.4 13.7 2.8 2.8 36.0 9.5 8.3 3.8 15.2 6.3 12.6 12.2 27.3 23.5 0.8 2.0 2.7 2.9 10.0 3.7 5.2 6.0 28.4 3.3 3.0 2.5 76.7 3.7 8.0 11.7 1.3 4.6 13.2 4.5 5.7 6.6 35.7 2.3 6.4 6.0 7.1 4.7 2.9 18.6 21.2 3.5 18.8 9.9 5.0 0.1 5.2 19.8 22.4 215.1 460.7 0.2 175.8 62.9 51.1 32.4 0.1 0.3 0.1 7.9 420.8 0.4 0.7 3.9 0.6 45.9 20.7 1.2 2.0 88.5 0.2 120.7 0.8 0.3 251.3 0.1 135.9 15.6 211.1 55.5 1.6 0.0 0.4 55.6 0.0 1.5 0.2 4.0 0.2 7.1 0.1 17.0 0.2 5.9 0.5 0.2 12.9 0.0 2.2 0.1 15.3 0.2 1.4 106.8 206.9 6.2 305.8 37.6 1.2 1.0 0.0 138.9 0.3 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 5.4 2.8 2.8 0.8 2.0 5.2 6.0 3.7 2.3 4.7 5.0 50.0 0.0 1.3 34.9 0.4 25.6 0.8 1.5 0.6 6.1 1.3 3.4 14.2 0.0 5.8 12.9 0.0 132.4 0.4 0.0 0.0 0.2 8.7 4.2 105.2 36.1 0.0 5.5 82.3 0.6 40.8 388.5 3.1 2.0 1.3 22.5 34.6 0.6 15.3 0.0 123.5 0.0 0.0 0.8 39.0 22.8 236.1 5.7 42.7 30.0 2.3 0.8 0.0 76.9 218.7 1.7 0.0 227.2 1.7 0.7 0.1 0.6 3.3 0.2 26.3 139.5 55.8 3.3 3.4 0.8 20.6 65.8 4.3 51.3 0.0 0.2 FBN2 "CCA, DA9" ENSG00000138829 "Fibrillin 2" P35556 5 128257909-128659185 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "placenta: 81.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 298.1;Syncytiotrophoblasts: 163.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Lineage enriched" "Detected in single" 5 "monocytes: 2.2" "Cell line enhanced" "Detected in many" "HHSteC: 134.1;HSkMC: 94.3;hTERT-HME1: 215.2;HUVEC TERT2: 122.3" "Region enhanced" "Detected in single" "olfactory bulb: 2.0" "Low region specificity" "Detected in many" "HPA012853, CAB026401" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 11000000 "Cluster 14: Monocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol Nucleoplasm "CAB026401: , HPA012853: AB_1848588" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (7.29e-3)" "unprognostic (1.79e-3)" "unprognostic (6.74e-2)" "unprognostic (2.33e-1)" "unprognostic (4.92e-3)" "unprognostic (9.41e-2)" "unprognostic (1.06e-2)" "unprognostic (4.66e-1)" "unprognostic (1.12e-1)" "unprognostic (8.69e-2)" "unprognostic (8.60e-5)" "unprognostic (1.04e-2)" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (7.41e-5)" 0.1 5.1 0.4 0.8 0.5 3.1 0.2 0.0 0.3 2.2 3.0 0.8 0.3 1.7 0.1 0.1 0.4 0.3 5.5 0.2 0.6 0.1 0.1 0.2 0.5 1.1 1.9 0.5 0.2 0.0 0.8 81.9 0.5 0.8 1.2 0.9 0.3 0.4 0.2 0.2 0.4 1.3 0.5 0.4 0.8 7.4 0.8 0.2 0.5 0.4 0.9 0.5 0.7 0.3 0.0 16.4 58.2 0.0 9.4 16.6 11.8 62.8 0.0 56.0 41.8 0.2 0.0 0.0 0.1 85.5 0.0 9.2 37.6 9.8 52.7 0.1 13.8 0.0 27.3 0.2 134.1 8.4 0.0 94.3 5.3 24.1 215.2 17.9 122.3 0.0 0.0 0.0 35.8 0.1 0.0 3.4 24.5 0.0 18.2 19.2 18.1 0.0 0.1 0.0 0.5 0.0 0.4 0.2 0.6 48.0 0.0 18.7 0.0 22.1 41.9 66.8 0.3 0.0 0.0 0.0 6.9 0.0 23.8 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.2 0.4 0.5 0.0 0.3 0.2 0.6 1.1 1.9 0.5 0.5 0.8 0.3 0.1 0.0 0.5 1.6 0.2 0.0 0.1 1.2 0.6 0.0 0.3 0.3 12.7 0.0 1.4 0.0 0.0 298.1 0.0 0.0 0.0 0.3 3.8 10.0 3.9 1.0 0.0 0.0 1.1 0.0 24.3 8.8 0.0 4.7 0.0 0.1 0.0 0.0 34.0 0.0 50.5 0.0 0.0 10.7 0.4 7.2 1.2 2.7 1.8 1.9 6.2 3.8 0.0 17.6 1.5 0.1 0.0 2.2 0.0 2.0 0.0 0.2 1.6 0.1 6.6 0.1 3.5 10.7 3.5 0.1 0.4 163.5 0.1 8.4 0.1 0.1 FBXL3 "FBL3, FBL3A, FBXL3A" ENSG00000005812 "F-box and leucine rich repeat protein 3" Q9UKT7 13 76992598-77027195 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053283, HPA065626" Enhanced "Nuclear bodies" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear bodies" "HPA053283: AB_2682100, HPA065626: AB_2685523" "unprognostic (3.98e-1)" "unprognostic (3.00e-2)" "unprognostic (1.55e-2)" "unprognostic (7.24e-2)" "unprognostic (9.92e-2)" "unprognostic (1.01e-1)" "unprognostic (2.75e-1)" "unprognostic (2.23e-1)" "unprognostic (5.12e-2)" "unprognostic (8.70e-2)" "unprognostic (2.81e-1)" "unprognostic (4.24e-2)" "unprognostic (1.10e-3)" "unprognostic (8.52e-2)" "unprognostic (1.43e-1)" "unprognostic (1.97e-1)" "unprognostic (2.78e-1)" 45.7 25.0 17.9 24.0 20.4 69.1 42.6 23.5 26.1 31.7 12.4 27.4 24.0 31.4 23.1 27.9 27.4 24.2 25.1 17.1 17.5 37.8 31.4 29.8 32.7 17.6 17.4 44.6 20.8 29.7 9.7 32.5 18.3 29.9 25.1 21.1 22.9 26.2 30.0 30.5 25.0 27.8 18.5 31.3 22.2 30.0 17.0 36.2 48.0 37.9 31.4 25.4 23.1 28.1 43.4 11.1 21.4 14.8 50.7 50.1 17.0 48.6 39.6 28.3 36.0 16.0 30.1 27.9 31.6 43.1 17.1 31.9 21.4 26.1 40.4 55.7 56.8 36.2 32.9 14.3 33.6 46.7 26.9 42.5 34.2 22.6 31.0 33.1 37.7 15.3 14.0 20.8 34.0 15.8 33.7 25.0 8.2 37.0 20.1 27.3 24.3 17.0 30.2 22.7 25.2 20.5 31.0 30.0 28.4 14.5 16.6 51.1 46.7 27.1 17.8 18.6 23.9 26.5 32.9 25.6 46.9 33.1 30.0 8.0 1.9 4.6 2.1 2.9 2.9 2.6 3.8 2.2 1.9 2.8 4.5 3.1 5.2 2.1 3.1 2.0 5.1 1.4 17.9 20.4 23.5 26.1 17.1 17.5 17.6 17.4 18.3 18.5 17.0 28.1 35.9 44.8 22.2 31.6 48.9 67.3 38.0 17.0 50.1 25.1 36.5 21.6 21.6 12.8 15.4 22.0 10.4 33.0 42.4 54.8 41.1 17.9 41.2 26.8 29.0 38.3 23.9 50.7 30.4 18.8 41.7 42.8 17.3 34.7 28.5 20.4 32.2 28.5 23.3 37.0 29.8 23.9 22.4 36.1 41.5 24.6 74.6 33.3 42.7 37.5 36.5 45.4 20.6 33.7 58.1 19.1 25.7 74.9 33.6 40.2 38.3 29.2 19.9 24.3 59.2 46.1 52.7 52.5 58.9 40.9 56.1 28.5 44.9 22.7 23.1 38.5 FDPS ENSG00000160752 "Farnesyl diphosphate synthase" P14324 1 155308748-155320666 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Host-virus interaction, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 355.7" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 927.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 1187.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028200 Approved Approved Nucleoplasm,Cytosol NA NA 1500000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol Nucleoplasm "HPA028200: AB_10612109" "unprognostic (1.23e-1)" "unprognostic (8.46e-3)" "unprognostic (2.47e-2)" "unprognostic (6.57e-2)" "unprognostic (4.58e-2)" "unprognostic (2.84e-2)" "prognostic unfavorable (7.35e-4)" "unprognostic (4.21e-2)" "unprognostic (6.78e-3)" "unprognostic (1.64e-3)" "unprognostic (7.19e-2)" "unprognostic (2.25e-2)" "unprognostic (1.11e-2)" "unprognostic (8.25e-2)" "unprognostic (2.07e-1)" "unprognostic (5.65e-2)" "unprognostic (8.44e-2)" 73.5 188.2 48.2 66.5 50.4 69.5 68.8 60.1 58.8 63.4 51.1 88.7 167.2 57.5 73.0 142.5 57.4 39.8 72.2 49.9 64.6 78.0 355.7 86.1 76.1 71.1 62.5 45.0 75.7 67.9 40.4 72.5 77.5 56.1 102.9 45.9 82.6 42.7 60.9 107.1 81.1 66.0 53.6 59.3 81.5 42.0 55.0 72.6 46.8 66.7 102.3 47.0 76.8 55.0 293.9 156.2 561.5 204.4 128.7 467.7 199.6 136.8 268.1 213.6 344.2 255.4 677.7 222.3 323.6 120.6 506.9 319.1 338.9 1187.5 198.9 122.4 242.5 129.4 260.1 311.5 210.8 212.1 142.0 335.5 184.6 339.6 168.8 96.4 377.6 322.3 235.1 579.9 225.3 315.1 273.6 205.0 338.9 216.4 225.5 231.6 243.2 620.0 567.7 193.0 217.4 185.6 140.7 253.0 243.0 317.3 182.6 567.6 277.1 118.4 144.3 74.3 254.9 244.3 202.3 401.1 115.3 221.7 191.1 90.6 85.5 124.1 89.2 92.9 79.7 102.8 77.8 91.1 95.6 95.1 69.9 87.1 38.9 115.2 70.0 76.2 113.7 134.7 48.2 50.4 60.1 58.8 49.9 64.6 71.1 62.5 77.5 53.6 55.0 55.0 154.2 73.7 181.6 38.5 68.4 36.8 83.3 927.7 42.1 69.4 84.6 56.9 1.8 97.2 431.5 53.3 62.6 207.8 74.9 343.0 137.0 180.9 216.6 56.7 38.2 161.9 71.4 133.4 30.8 329.9 198.7 59.8 52.0 77.8 62.8 116.6 168.1 361.9 112.0 55.5 28.1 135.7 299.1 54.8 44.4 67.9 60.9 52.8 96.0 15.0 144.7 81.1 87.6 22.6 39.7 256.7 324.3 70.3 91.3 206.1 194.1 145.0 129.6 90.8 72.3 47.0 177.5 42.0 14.2 49.7 59.8 143.5 68.3 230.6 165.4 148.2 FGD1 "FGDY, ZFYVE3" ENSG00000102302 "FYVE, RhoGEF and PH domain containing 1" P98174 X 54445454-54496234 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 16.1;Granulosa cells: 12.6;Inhibitory neurons: 15.2" "Cancer enhanced" "Detected in all" "testis cancer: 28.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000911, HPA076516" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "HPA000911: AB_1078853, HPA076516: " "unprognostic (2.49e-1)" "unprognostic (1.56e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (8.74e-2)" "unprognostic (1.57e-2)" "unprognostic (2.94e-2)" "unprognostic (2.77e-3)" "unprognostic (1.49e-1)" "unprognostic (3.40e-3)" "unprognostic (1.70e-2)" "unprognostic (4.92e-2)" "unprognostic (3.41e-2)" "unprognostic (9.40e-3)" 3.9 5.1 8.2 1.6 6.2 0.0 3.6 5.3 7.6 7.0 2.4 5.6 1.0 7.1 1.6 5.8 5.1 2.2 5.0 8.3 5.2 3.5 1.1 2.8 0.5 3.8 4.1 7.4 3.2 3.6 3.6 3.4 3.7 4.3 1.6 1.6 3.4 3.3 1.3 5.4 2.8 5.4 3.5 2.4 3.5 2.4 4.9 0.4 3.3 1.0 1.0 4.8 5.4 4.6 18.5 6.9 13.2 19.3 7.8 13.8 6.2 10.4 12.8 10.6 8.5 0.6 0.4 0.0 8.2 19.9 9.6 5.3 14.6 9.0 5.8 1.0 8.9 0.0 5.0 2.2 8.3 0.0 0.0 11.3 5.6 16.1 7.6 9.4 9.7 2.3 2.0 0.0 8.4 2.4 0.7 0.0 12.6 0.0 10.2 9.4 6.7 0.0 9.1 0.3 13.1 11.9 10.3 0.2 16.6 21.0 10.3 0.4 6.9 10.5 8.7 23.0 9.4 0.1 0.2 0.1 11.0 0.6 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 6.2 5.3 7.6 8.3 5.2 3.8 4.1 3.7 3.5 4.9 4.6 3.2 0.0 0.0 4.6 0.0 2.9 1.2 2.0 5.2 2.5 3.2 3.9 3.4 0.0 0.7 0.0 0.0 0.5 0.1 0.2 0.0 1.6 0.4 1.3 7.0 4.2 1.2 0.0 16.1 1.1 1.0 5.1 1.5 2.1 0.0 12.6 2.9 0.3 0.4 1.7 15.2 1.0 0.0 0.0 1.0 0.6 2.8 0.1 7.2 5.6 0.0 2.3 0.0 7.1 1.8 0.5 0.5 4.1 0.1 1.6 0.1 1.4 0.3 3.5 0.0 2.3 4.0 0.3 2.2 5.5 4.1 0.3 0.1 2.9 2.8 1.0 FGF10 ENSG00000070193 "Fibroblast growth factor 10" O15520 5 44300247-44389706 "Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Disease variant, Ectodermal dysplasia, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 21.6;Fibroblasts: 14.6;Leydig cells: 8.4;Muller glia cells: 4.3;Peritubular cells: 10.5" "Cancer enriched" "Detected in some" 6 "breast cancer: 5.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "AF22: 27.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB010315 Uncertain "Secreted in other tissues" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "CAB010315: AB_2262731" "unprognostic (1.40e-1)" "unprognostic (1.25e-1)" "unprognostic (8.54e-2)" "unprognostic (1.08e-1)" "unprognostic (3.39e-2)" "unprognostic (1.20e-1)" "unprognostic (3.54e-2)" "unprognostic (4.06e-3)" "unprognostic (2.72e-2)" "unprognostic (6.73e-2)" "unprognostic (5.59e-2)" "unprognostic (4.55e-2)" "unprognostic (1.24e-2)" "unprognostic (1.11e-2)" "unprognostic (2.14e-2)" "unprognostic (5.23e-4)" 13.9 1.6 0.3 2.6 0.9 0.0 15.2 0.5 0.7 14.6 1.1 7.0 0.4 2.4 4.4 1.4 8.5 2.8 0.7 0.6 0.7 0.7 0.1 2.6 0.6 1.3 1.9 17.3 4.8 0.0 2.1 5.5 1.1 4.6 1.5 0.3 5.4 3.0 0.7 0.9 2.9 1.3 1.6 0.0 4.3 0.8 1.7 1.1 5.3 3.8 0.2 5.0 12.0 0.4 0.0 0.0 27.9 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.5 0.7 0.6 0.7 1.3 1.9 1.1 1.6 1.7 0.4 1.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 21.6 0.9 0.0 0.0 3.0 0.5 0.0 14.6 0.0 0.3 0.0 1.6 0.4 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.5 8.4 0.1 0.0 0.0 0.0 4.3 0.0 0.0 0.3 0.3 0.0 10.5 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 FGF16 MF4 ENSG00000196468 "Fibroblast growth factor 16" O43320 X 77447389-77457278 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "choroid plexus: 1.8" "Cell type enhanced" "Detected in some" "Fibroblasts: 1.5;Melanocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-2197: 22.5" "Group enriched" "Detected in some" 6 "basal ganglia: 3.6;hippocampal formation: 2.0;olfactory bulb: 6.7" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.01e-2)" "unprognostic (5.30e-2)" "unprognostic (1.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.31e-1)" "unprognostic (6.57e-2)" "unprognostic (1.49e-2)" 0.6 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.3 0.1 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 FGF20 ENSG00000078579 "Fibroblast growth factor 20" Q9NP95 8 16992181-17002345 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.5" "Cell type enriched" "Detected in some" 7 "Microglial cells: 8.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.6;CAPAN-2: 5.3;OE19: 1.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 1.8" "Secreted in other tissues" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "unprognostic (1.93e-2)" "unprognostic (2.19e-1)" "unprognostic (5.57e-3)" "unprognostic (3.95e-2)" "unprognostic (1.59e-3)" "unprognostic (1.40e-2)" "unprognostic (1.94e-1)" "unprognostic (2.65e-2)" "unprognostic (9.32e-2)" "unprognostic (9.95e-2)" "unprognostic (3.92e-1)" "unprognostic (4.08e-2)" 0.1 0.6 0.8 0.0 0.8 0.0 0.2 2.5 1.4 0.9 0.5 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.1 0.8 1.2 0.0 0.0 0.1 0.1 1.1 1.2 0.6 0.1 0.0 0.4 0.1 1.4 0.2 0.0 0.1 1.1 0.1 0.0 0.0 0.1 0.0 1.1 1.0 0.6 0.2 1.4 0.2 0.2 0.0 0.4 0.1 0.1 1.6 0.0 0.0 0.1 0.0 0.4 0.6 0.0 0.6 1.6 0.2 0.8 0.0 5.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 2.5 1.4 0.8 1.2 1.1 1.2 1.4 1.1 1.4 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 1.0 0.0 0.0 0.0 1.2 0.0 8.4 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 FGF3 "HBGF-3, INT2" ENSG00000186895 "Fibroblast growth factor 3" P11487 11 69809968-69819416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "brain: 3.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.4" "Region enriched" "Detected in single" 5 "cerebellum: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 3.1" "Not detected" "Not detected" HPA012692 Enhanced "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA012692: AB_1848526" "unprognostic (6.42e-3)" "unprognostic (7.82e-2)" "unprognostic (1.89e-1)" "unprognostic (3.61e-1)" "unprognostic (7.75e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.1 0.6 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FGF9 ENSG00000102678 "Fibroblast growth factor 9" P31371 13 21671073-21704498 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 10.7;retina: 8.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 39.2;Excitatory neurons: 36.7;Horizontal cells: 40.4;Inhibitory neurons: 54.7;Muller glia cells: 138.8" "Group enriched" "Detected in some" 5 "endometrial cancer: 3.7;ovarian cancer: 1.2;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.4;HEK 293: 1.4;JURKAT: 2.1;RPMI-8226: 2.1;RPTEC TERT1: 3.0;SCLC-21H: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067007 Enhanced Approved "Secreted in other tissues" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 5: Muller glia cells - Visual perception" "HPA067007: AB_2732755" "unprognostic (6.59e-3)" "unprognostic (9.09e-3)" "unprognostic (2.15e-2)" "unprognostic (9.24e-2)" "unprognostic (2.19e-1)" "unprognostic (2.37e-2)" "unprognostic (7.42e-4)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (3.86e-1)" "unprognostic (2.38e-3)" "unprognostic (7.93e-2)" "prognostic favorable (1.70e-6)" "unprognostic (5.38e-2)" "unprognostic (1.27e-1)" "unprognostic (3.49e-1)" "unprognostic (6.92e-2)" 2.4 4.0 1.1 0.1 1.4 0.2 0.2 5.8 4.7 1.5 0.2 0.8 0.7 1.6 0.2 0.2 0.4 0.4 2.7 1.3 1.9 10.7 0.0 0.9 0.1 3.7 1.6 1.0 0.5 0.1 2.2 0.1 4.3 0.3 1.2 8.2 0.3 0.5 0.5 0.1 1.8 0.3 1.2 0.1 0.8 0.5 3.0 0.1 0.1 0.5 0.0 1.2 0.8 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.9 0.5 0.0 0.0 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.6 2.1 3.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.4 5.8 4.7 1.3 1.9 3.7 1.6 4.3 1.2 3.0 2.1 0.9 9.6 5.6 12.1 1.8 1.7 0.2 0.6 0.0 14.4 0.7 2.7 25.7 0.0 1.3 3.7 0.0 0.1 3.2 1.7 39.2 0.4 9.4 13.1 2.6 1.6 18.6 0.0 36.7 0.0 0.0 3.9 0.0 26.6 0.0 1.2 0.0 0.0 0.1 40.4 54.7 2.7 0.0 0.0 1.6 2.9 0.6 0.5 1.8 1.9 1.6 138.8 3.1 9.5 1.7 0.2 0.5 0.0 1.9 0.1 10.9 1.1 0.0 5.9 0.0 1.0 0.7 6.3 6.2 0.1 1.4 0.3 3.2 0.1 7.5 0.1 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Kallmann syndrome, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 176.7;Leydig cells: 192.0;Oligodendrocyte precursor cells: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 508.7;BJ hTERT+: 278.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" 95.1 12.8 27.5 15.9 24.6 14.1 87.1 48.8 22.4 79.8 37.2 97.2 8.8 74.2 15.8 35.8 85.9 57.1 89.9 30.9 28.8 40.1 9.1 55.7 16.6 35.9 37.3 108.2 98.6 20.4 57.1 51.3 63.7 60.5 17.9 15.8 31.4 53.6 24.8 35.6 41.7 57.1 30.3 9.9 40.4 20.4 33.4 17.1 33.7 23.3 16.1 79.3 63.9 29.6 12.9 42.0 198.0 508.7 120.1 91.2 142.9 136.7 278.8 90.0 95.8 27.3 6.5 1.8 38.3 127.7 103.9 0.2 90.0 6.8 104.3 39.2 24.1 0.0 7.7 27.8 69.7 31.1 0.6 80.5 0.7 70.9 13.3 45.6 86.9 6.0 11.9 0.4 40.5 12.5 91.5 9.2 145.9 1.6 21.6 86.3 21.1 0.4 35.6 0.3 7.9 19.4 23.4 1.0 5.1 93.4 9.3 5.4 51.4 49.2 28.9 149.6 29.7 2.4 4.1 0.5 60.3 1.7 27.1 0.2 0.3 0.1 1.7 0.1 1.1 0.3 0.7 1.2 0.0 0.6 0.5 1.5 0.6 0.4 0.2 0.2 1.0 0.1 27.5 24.6 48.8 22.4 30.9 28.8 35.9 37.3 63.7 30.3 33.4 29.6 101.0 3.2 15.8 55.8 1.8 31.5 95.9 1.1 37.0 4.4 28.7 77.7 52.5 24.3 5.1 9.2 4.2 8.3 6.3 0.4 0.0 27.3 15.3 48.2 40.6 75.5 25.0 3.6 25.4 65.2 80.5 176.7 3.1 75.3 8.2 40.4 47.5 0.8 25.3 21.9 21.1 0.6 4.1 5.6 75.2 15.0 192.0 11.7 33.8 19.7 1.7 88.1 6.2 166.4 14.2 21.6 0.3 99.6 6.4 94.7 0.1 7.9 1.0 3.3 13.1 118.9 59.9 1.6 14.1 4.8 19.7 10.4 14.1 2.1 0.7 11.7 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cell line enhanced" "Detected in many" "AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 5.7 21.3 103.9 8.2 186.8 0.3 22.9 178.9 198.9 19.7 198.1 44.8 10.4 54.6 15.3 25.2 29.6 31.3 5.6 109.9 124.7 26.3 41.0 30.9 2.9 250.9 185.9 18.0 31.0 61.0 6.8 15.7 220.5 27.4 21.2 1.2 59.1 54.6 0.5 109.3 12.2 43.6 165.5 0.8 22.5 7.6 148.0 10.1 54.6 0.2 9.1 16.6 27.4 273.8 7.2 0.4 30.2 189.0 0.1 0.0 60.9 0.4 0.0 0.0 0.0 49.6 1.1 0.1 12.5 2.8 0.1 55.6 63.7 13.0 0.0 0.1 12.7 0.0 0.2 1.2 1.5 0.2 11.7 0.1 26.2 0.0 0.6 0.0 0.0 0.3 0.2 0.2 0.0 11.7 0.2 0.1 57.8 8.7 0.0 0.1 0.0 7.5 18.0 15.8 0.5 0.5 0.4 33.4 0.0 36.6 49.3 0.0 0.1 0.3 8.5 0.2 0.7 0.1 0.1 0.0 0.3 0.0 0.5 13.2 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 103.9 186.8 178.9 198.9 109.9 124.7 250.9 185.9 220.5 165.5 148.0 273.8 1.4 19.2 36.0 228.2 0.6 40.1 34.3 18.4 58.6 0.2 8.7 25.4 9.1 213.1 38.4 36.8 0.0 16.5 0.3 7.3 0.0 7.4 4.1 28.1 4.4 1.0 2.4 2.7 14.8 0.2 3.0 9.0 13.3 53.1 0.0 0.1 1.8 5.0 2.3 0.0 31.2 40.8 10.2 0.6 4.4 9.6 1.2 1.1 5.4 10.3 0.6 2.0 1.0 6.0 562.5 0.7 3.0 6.0 0.1 15.0 1.8 13.6 15.3 0.2 0.0 1.6 2.6 0.7 9.9 18.7 27.7 4.0 1.5 0.4 3.8 31.4 FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 148.3;esophagus: 139.7;skin 1: 271.5" "Cell type enhanced" "Detected in many" "Astrocytes: 410.4;Basal keratinocytes: 103.8;Cholangiocytes: 91.5;Suprabasal keratinocytes: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 48.2;HaCaT: 34.9;Hep G2: 80.6;NTERA-2: 36.1;RT4: 64.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" NA NA 2500000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: AB_2685804" "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" 1.6 1.6 118.0 1.5 140.6 1.4 5.5 115.6 104.0 23.7 37.4 12.2 19.5 1.5 2.8 139.7 2.2 7.9 4.8 100.8 107.6 39.3 40.7 7.4 0.4 144.7 129.2 0.5 76.4 0.2 16.1 9.3 109.8 13.8 5.2 0.2 20.2 15.0 1.3 271.5 14.7 0.4 108.9 4.0 7.8 17.6 148.3 1.7 1.5 0.9 11.1 23.1 60.9 81.2 0.0 3.8 19.5 5.6 0.0 0.3 22.1 2.4 0.3 0.8 0.4 48.2 1.0 0.0 17.8 0.7 0.7 34.9 5.5 0.3 0.3 0.2 19.3 14.2 3.9 80.6 0.1 0.0 0.6 0.0 10.9 0.2 0.1 0.1 0.1 2.3 16.7 0.1 0.0 23.9 0.8 0.5 36.1 19.5 0.1 1.2 1.0 0.3 2.8 64.1 5.7 1.6 1.9 4.0 0.0 22.2 20.4 2.5 1.0 0.0 2.1 0.5 1.6 0.1 0.0 0.0 0.2 1.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 118.0 140.6 115.6 104.0 100.8 107.6 144.7 129.2 109.8 108.9 148.3 81.2 2.2 0.0 32.5 410.4 1.1 103.8 4.1 29.8 23.9 0.0 4.8 1.5 3.1 91.5 37.6 14.7 0.0 0.5 1.6 36.1 0.0 5.0 7.9 3.0 1.7 3.4 4.2 0.0 0.5 0.7 12.0 3.2 3.6 4.0 0.0 0.1 16.1 30.4 0.6 0.0 1.3 20.7 4.1 1.2 6.5 1.3 0.6 0.6 12.4 14.0 0.6 0.1 0.0 34.2 2.2 0.4 18.0 0.4 0.0 4.2 21.2 9.9 9.8 0.6 0.0 0.7 2.9 0.4 25.9 55.0 88.7 0.8 0.7 0.1 17.0 12.8 FIBP FGFIBP ENSG00000172500 "FGF1 intracellular binding protein" O43427 11 65883740-65888531 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 608.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011729 Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA011729: AB_1848579" "unprognostic (1.70e-1)" "unprognostic (6.06e-2)" "unprognostic (1.06e-1)" "unprognostic (3.35e-1)" "unprognostic (1.37e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (1.74e-4)" "unprognostic (2.23e-1)" "unprognostic (2.95e-1)" "unprognostic (3.10e-3)" "unprognostic (2.13e-1)" "unprognostic (1.29e-1)" "unprognostic (5.50e-2)" "unprognostic (2.39e-1)" "unprognostic (3.18e-1)" "unprognostic (1.83e-2)" "unprognostic (4.89e-2)" 34.1 48.4 48.0 26.8 49.0 32.2 33.0 48.0 55.1 31.1 41.8 30.8 30.4 35.9 29.4 35.6 37.2 22.3 56.8 51.0 50.5 48.3 37.1 31.6 35.6 53.3 47.6 28.6 39.0 32.8 31.2 25.1 54.3 30.6 27.3 19.8 27.9 24.6 53.6 45.7 35.3 30.9 46.6 43.3 37.7 64.9 49.9 40.3 35.9 56.1 42.9 29.7 28.3 47.8 61.0 86.9 48.3 118.6 72.8 91.2 35.9 54.8 110.9 74.3 62.0 36.1 83.1 79.7 98.2 124.1 35.9 65.2 48.5 121.0 48.1 93.7 62.2 77.3 84.1 54.7 99.8 100.7 64.4 73.8 68.3 54.1 114.4 60.0 93.7 61.5 27.4 139.4 98.9 198.2 78.9 88.0 47.8 61.5 130.7 104.9 45.6 196.3 88.5 79.6 87.8 80.4 60.3 110.6 110.5 32.5 113.0 58.1 86.3 79.7 66.4 130.9 40.3 73.8 87.6 48.4 101.1 73.6 30.7 123.5 121.2 98.9 71.1 136.9 74.4 100.7 67.2 64.9 164.7 83.1 52.7 57.0 20.4 101.1 150.0 84.1 100.6 109.4 48.0 49.0 48.0 55.1 51.0 50.5 53.3 47.6 54.3 46.6 49.9 47.8 55.8 12.8 28.0 4.9 57.0 47.3 51.7 105.7 38.7 47.7 66.9 85.6 44.7 42.9 55.7 44.1 31.3 79.4 41.1 61.6 93.9 114.2 176.7 45.3 59.8 52.6 93.5 39.1 7.1 149.3 125.7 50.3 37.2 39.6 67.2 68.6 45.3 36.5 115.0 42.1 7.3 49.2 57.0 75.3 75.9 608.0 36.1 67.9 51.6 3.7 129.3 47.1 101.0 3.5 5.6 98.9 68.8 39.5 60.1 56.1 185.8 150.1 54.9 52.8 19.7 39.2 77.2 100.5 84.0 51.5 52.1 71.8 54.6 79.6 58.8 61.5 FIG4 "ALS11, CMT4J, dJ249I4.1, hSac3, KIAA0274, SAC3" ENSG00000112367 "FIG4 phosphoinositide 5-phosphatase" Q92562 6 109690609-109878098 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.5;Oligodendrocyte precursor cells: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017823, HPA068859" Approved Supported "Vesicles,Lipid droplets" NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Lipid droplets" "CAB017823: , HPA068859: AB_2686049" "prognostic unfavorable (5.91e-4)" "unprognostic (4.12e-2)" "prognostic favorable (8.42e-4)" "unprognostic (3.17e-2)" "unprognostic (1.66e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.73e-4)" "unprognostic (7.06e-2)" "unprognostic (2.69e-1)" "unprognostic (8.67e-2)" "unprognostic (3.44e-3)" "unprognostic (4.22e-2)" "prognostic favorable (8.19e-4)" "unprognostic (1.48e-1)" "unprognostic (2.02e-1)" "unprognostic (5.45e-2)" "unprognostic (2.00e-2)" 9.3 10.2 5.5 7.1 7.2 5.6 8.1 5.9 7.7 8.2 12.9 10.1 5.0 8.5 7.8 9.4 7.2 7.6 7.7 6.0 8.8 9.5 6.1 13.4 10.1 6.4 7.3 8.2 7.5 17.4 11.9 8.8 8.9 7.7 9.5 10.8 10.7 7.8 10.6 7.6 9.1 10.3 5.6 13.8 8.7 8.2 6.1 12.3 9.3 8.3 10.1 9.2 8.4 7.0 8.3 8.4 11.7 14.9 11.8 17.2 7.8 9.9 14.1 8.3 23.2 4.6 7.2 23.2 5.8 18.9 14.9 5.2 12.6 8.5 20.7 13.3 16.5 10.9 5.9 5.5 11.4 9.5 10.0 8.8 9.9 12.8 10.6 22.8 18.3 13.9 6.8 8.8 12.7 6.8 12.0 8.4 5.9 12.0 4.7 7.9 6.1 7.3 13.3 18.4 12.8 11.7 7.1 10.7 21.1 15.6 6.0 23.1 11.2 4.2 3.8 5.4 9.5 3.4 2.6 7.9 27.3 8.5 4.6 15.4 24.9 14.2 8.8 24.5 7.7 18.9 6.3 8.5 19.2 21.2 7.5 7.5 7.4 10.0 15.2 8.1 9.4 11.7 5.5 7.2 5.9 7.7 6.0 8.8 6.4 7.3 8.9 5.6 6.1 7.0 4.9 16.0 9.0 24.5 15.7 4.6 7.1 7.3 5.2 8.8 5.4 3.3 6.7 2.8 6.9 9.2 2.1 13.4 9.5 7.0 5.9 9.8 18.0 7.5 5.3 5.2 10.2 3.0 49.5 11.4 7.0 6.0 8.2 7.9 8.8 8.6 7.1 4.1 23.3 1.7 32.4 8.6 8.2 19.2 6.8 17.7 3.4 17.3 8.8 29.0 16.4 8.5 11.3 46.8 37.4 7.6 6.3 6.8 6.5 4.0 6.3 8.2 9.1 7.6 0.0 5.1 6.6 5.5 12.1 8.3 4.4 12.3 9.3 5.6 6.4 8.9 FKBP10 "FKBP6, FKBP65, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FKBP prolyl isomerase 10" Q96AY3 17 41812680-41823213 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 79.1;Fibroblasts: 100.0;Sertoli cells: 59.2;Smooth muscle cells: 65.3;Theca cells: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 551.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051171, HPA057021" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 22: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA051171: AB_2681371, HPA057021: AB_2683312" "unprognostic (8.30e-2)" "prognostic unfavorable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavorable (3.43e-5)" "prognostic unfavorable (4.99e-4)" 39.4 39.5 20.9 27.1 22.2 0.5 33.5 21.7 26.1 64.0 22.0 29.1 7.6 61.5 16.9 13.9 50.9 46.0 45.6 20.3 22.1 17.7 7.8 37.8 10.9 24.6 21.6 58.4 15.1 48.5 56.7 60.7 22.2 32.6 10.8 6.0 14.7 30.8 7.6 20.4 19.1 55.6 21.9 14.3 18.5 9.0 24.2 4.9 34.9 9.3 4.4 42.2 39.1 21.6 0.7 119.6 110.7 363.3 379.3 441.7 92.0 490.4 497.4 185.6 159.0 62.1 4.8 0.3 6.6 551.9 45.9 0.8 66.7 133.4 77.9 33.0 99.9 48.6 132.1 181.0 411.4 0.0 0.6 476.1 0.5 150.3 115.5 352.6 158.8 0.0 1.9 16.7 157.0 163.2 0.3 0.1 85.4 258.0 38.3 9.9 125.2 15.7 31.7 0.1 26.7 92.1 0.7 349.3 166.0 137.4 54.1 3.1 181.0 219.0 111.5 145.8 76.0 0.8 0.2 0.3 299.7 0.0 213.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.9 22.2 21.7 26.1 20.3 22.1 24.6 21.6 22.2 21.9 24.2 21.6 14.9 0.0 4.8 38.2 0.2 8.5 11.5 2.7 1.2 0.6 10.8 13.2 2.3 1.5 1.4 0.0 0.0 6.1 0.2 0.1 0.0 8.7 0.7 3.0 79.1 34.9 0.0 0.0 0.3 4.7 30.8 100.0 1.5 4.6 0.0 32.9 30.4 0.0 4.7 15.2 0.3 1.3 0.0 0.0 9.7 2.9 46.9 1.5 16.0 15.0 0.0 32.0 0.0 17.1 0.1 2.2 0.1 44.8 0.5 8.2 0.0 0.0 0.1 1.1 59.2 35.2 65.3 0.9 7.6 0.5 5.1 11.9 2.1 54.0 0.6 1.6 FKBP14 "FKBP22, FLJ20731" ENSG00000106080 "FKBP prolyl isomerase 14" Q9NWM8 7 30010587-30026702 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Deafness, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013329, HPA026829" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" Cytosol "Nucleoplasm, Golgi apparatus" "HPA013329: AB_1848613, HPA026829: AB_10601651" "prognostic unfavorable (1.60e-4)" "unprognostic (1.12e-3)" "unprognostic (6.84e-2)" "unprognostic (1.23e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (6.06e-2)" "unprognostic (7.00e-2)" "unprognostic (6.99e-2)" "unprognostic (2.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.93e-3)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-3)" "prognostic unfavorable (4.25e-4)" 6.5 5.1 3.4 7.0 3.5 4.3 6.4 5.4 3.6 9.9 3.1 4.7 3.0 8.5 10.0 4.7 4.3 6.0 6.8 3.2 3.2 3.1 3.2 4.1 3.1 3.3 3.1 5.4 5.8 6.2 7.7 7.9 3.0 6.8 4.8 7.2 4.3 7.5 2.1 4.7 2.9 13.9 3.0 2.7 4.0 2.2 3.5 1.8 3.3 3.2 3.2 8.9 3.8 3.5 7.0 5.2 14.4 33.6 36.8 46.8 6.5 34.9 32.7 12.0 23.3 4.4 4.3 2.4 16.0 31.0 14.7 14.8 8.1 12.8 23.9 1.3 11.6 5.6 9.2 13.1 18.6 4.0 9.3 29.4 13.1 20.9 24.6 28.2 27.0 3.6 9.2 5.0 21.8 2.9 2.1 4.9 7.5 7.7 9.2 0.1 9.6 8.2 11.8 6.1 3.8 12.5 12.2 27.5 8.8 17.0 6.2 5.3 21.7 12.6 14.6 21.8 14.0 7.6 8.3 4.2 18.0 3.8 40.2 0.5 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.4 0.2 0.0 0.6 0.2 0.1 3.4 3.5 5.4 3.6 3.2 3.2 3.3 3.1 3.0 3.0 3.5 3.5 13.5 19.2 16.0 7.2 7.9 27.4 22.0 15.8 35.9 16.3 13.3 13.0 15.7 5.7 11.7 18.4 27.1 11.6 9.4 5.3 1.9 7.4 0.4 30.4 44.3 12.9 1.2 6.5 19.4 3.7 27.3 40.0 15.3 40.0 2.5 9.1 8.6 6.5 6.0 15.2 12.7 9.7 8.2 2.5 11.2 0.4 13.1 5.7 10.6 10.3 3.6 26.5 2.1 11.6 16.6 5.7 19.0 20.7 43.8 17.8 3.3 2.7 6.0 21.4 6.6 13.8 20.4 1.4 3.4 27.5 18.3 15.7 6.0 20.8 6.1 28.0 FLG ENSG00000143631 Filaggrin P20930 1 152302165-152325239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 458.2" "Cell type enriched" "Detected in some" 13 "Suprabasal keratinocytes: 44.0" "Cancer enriched" "Detected in some" 7 "melanoma: 11.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 10.1;NTERA-2: 3.1;TIME: 2.1;U-2 OS: 2.4;U-2197: 2.6;WM-115: 2.0" "Not detected" "Not detected" "CAB002210, HPA027505, HPA030188, HPA030189" Enhanced Enhanced "Cytoplasmic bodies" NA NA 3800000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Cytoplasmic bodies" "CAB002210: AB_563731, HPA027505: AB_10600107, HPA030188: AB_10601749, HPA030189: AB_10601999" "unprognostic (3.37e-2)" "unprognostic (3.76e-1)" "unprognostic (8.83e-2)" "unprognostic (2.96e-3)" "unprognostic (9.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" "unprognostic (4.03e-2)" "unprognostic (1.12e-1)" "unprognostic (9.98e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-1)" "unprognostic (2.35e-2)" "unprognostic (1.45e-1)" "unprognostic (4.28e-2)" "unprognostic (4.15e-2)" "unprognostic (7.41e-3)" 0.3 0.4 0.7 0.1 0.3 0.1 15.7 0.3 0.4 6.5 0.0 0.2 0.0 0.5 0.0 12.0 0.4 0.1 0.4 0.3 1.4 0.4 0.2 0.2 0.0 1.6 0.9 0.9 0.4 0.0 0.2 0.0 1.2 0.2 0.0 0.2 2.7 0.0 1.8 458.2 0.1 0.0 0.8 0.1 0.2 0.3 0.8 0.5 0.3 0.0 0.5 0.1 4.9 0.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.0 10.1 0.0 0.0 0.0 1.1 0.0 0.8 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 2.1 0.8 2.4 2.6 1.9 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.3 0.4 0.3 1.4 1.6 0.9 1.2 0.8 0.8 0.6 0.0 0.0 0.0 0.0 0.0 3.2 0.0 1.0 0.0 0.6 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.0 44.0 0.0 0.1 0.1 0.0 0.0 FLG2 IFPS ENSG00000143520 "Filaggrin family member 2" Q5D862 1 152348735-152360006 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 483.9" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 24.2" "Cancer enriched" "Detected in some" 8 "melanoma: 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028699 Approved NA NA 21000000 "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA028699: AB_10601905" "unprognostic (2.58e-1)" "unprognostic (2.33e-1)" "unprognostic (3.08e-1)" "unprognostic (6.85e-2)" "unprognostic (6.59e-3)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (1.09e-1)" "unprognostic (2.08e-2)" "unprognostic (1.12e-1)" "unprognostic (1.96e-1)" 0.3 0.0 0.1 0.0 0.0 0.1 32.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 483.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.9 0.4 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.2 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.1 1.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.5 0.2 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 1.1 0.0 1.0 0.2 0.1 0.2 0.0 24.2 0.0 0.0 0.1 0.0 0.3 FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 1203.7;intestine: 1462.2" "Cell type enhanced" "Detected in many" "Peritubular cells: 500.6;Sertoli cells: 420.7;Smooth muscle cells: 459.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Enhanced "Plasma membrane,Actin filaments,Cytosol" NA NA 730000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: AB_2797215, HPA001016: , HPA001115: AB_1078871, HPA002925: AB_1078869" "unprognostic (1.39e-1)" "unprognostic (9.40e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (6.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.23e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.49e-3)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.88e-4)" 267.4 55.9 14.4 223.2 18.5 157.9 164.2 15.2 43.0 392.1 54.7 1462.2 89.9 1203.7 35.5 454.7 609.4 137.9 108.4 14.8 23.0 70.5 21.2 238.9 65.0 39.9 19.9 236.7 50.5 13.4 30.5 79.2 24.4 369.2 86.9 9.0 80.3 617.2 49.7 124.7 354.6 706.6 21.1 102.7 508.0 33.7 34.0 48.1 85.6 31.2 38.1 1053.9 286.4 21.5 947.2 719.2 246.7 316.1 209.8 278.4 400.9 614.0 680.1 552.5 489.8 469.2 169.4 80.5 1551.4 966.4 970.1 528.3 224.0 538.1 152.7 333.6 77.8 262.2 914.9 159.7 375.9 309.3 324.9 266.1 126.1 825.5 327.0 533.8 417.1 94.9 74.7 538.7 401.3 210.7 148.5 93.1 258.3 97.9 470.9 147.8 221.2 71.6 197.2 193.4 52.9 119.7 515.8 80.2 381.1 187.3 79.1 96.3 1016.6 625.2 586.8 640.0 1147.1 333.7 212.8 162.3 580.3 202.4 638.7 7.6 24.9 11.8 32.6 23.1 21.2 10.2 15.6 29.2 22.4 4.6 6.0 14.3 3.6 10.5 34.2 2.7 20.7 56.2 14.4 18.5 15.2 43.0 14.8 23.0 39.9 19.9 24.4 21.1 34.0 21.5 105.1 57.7 38.7 30.0 76.9 124.3 85.9 127.8 85.4 3.5 40.9 153.5 34.5 38.6 26.1 35.0 0.0 24.6 257.7 2.6 1.9 272.0 2.1 33.8 186.3 107.0 1.8 39.7 11.8 133.1 90.9 137.9 13.3 55.8 26.0 334.5 81.8 4.3 120.3 11.8 8.6 2.5 22.4 141.0 263.0 13.7 122.4 227.7 88.9 30.9 207.9 39.4 270.8 8.0 2.6 347.4 1.5 500.6 98.7 96.1 1.9 3.0 9.1 4.3 420.7 118.3 459.3 4.1 8.9 48.8 73.6 20.0 172.3 134.7 3.3 35.3 FLNB "ABP-278, FH1, FLN1L, LRS1, TABP, TAP" ENSG00000136068 "Filamin B" O75369 3 58008400-58172251 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Differentiation, Myogenesis" "Actin-binding, Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 344.9;Pancreatic endocrine cells: 385.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 17.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 523.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004747, HPA004886, CAB019322" Enhanced Supported "Golgi apparatus,Plasma membrane,Actin filaments,Cytosol" NA NA 20000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments, Cytosol" "CAB019322: , HPA004747: AB_1848599, HPA004886: AB_1848600" "unprognostic (1.29e-2)" "unprognostic (1.08e-2)" "unprognostic (5.97e-2)" "unprognostic (6.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (6.52e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (9.23e-2)" "prognostic favorable (3.45e-6)" "unprognostic (4.38e-2)" "unprognostic (1.36e-1)" "unprognostic (6.65e-3)" "unprognostic (2.33e-1)" 74.6 63.1 42.8 22.3 51.3 7.4 90.4 50.9 52.4 45.5 57.1 122.2 52.8 75.5 120.3 57.7 75.9 19.6 47.2 40.1 41.6 96.7 71.5 49.9 24.4 54.4 52.3 68.9 83.2 59.9 38.1 48.0 52.6 124.4 74.4 10.2 64.0 51.4 16.3 91.3 92.7 36.2 48.1 55.3 70.2 30.4 50.0 74.8 91.1 17.8 23.8 114.7 58.6 58.3 134.4 225.0 22.3 32.9 14.8 25.0 385.7 49.0 39.3 106.6 108.4 227.1 223.1 21.9 18.1 172.9 172.8 215.9 42.1 311.5 103.0 121.6 20.8 18.4 192.7 110.5 107.8 16.2 63.1 40.2 132.1 148.5 448.3 125.2 365.4 94.7 30.9 6.6 67.0 29.2 49.3 38.5 34.5 146.6 192.1 21.6 5.8 18.7 143.8 224.6 24.7 23.1 247.3 132.6 27.4 160.9 110.3 44.6 523.3 27.8 84.5 334.1 175.6 4.8 1.7 17.0 102.2 29.2 29.9 10.1 0.3 5.0 0.5 0.8 2.7 4.1 1.7 0.8 1.4 1.6 5.1 3.8 0.2 7.3 1.5 17.9 2.0 1.5 42.8 51.3 50.9 52.4 40.1 41.6 54.4 52.3 52.6 48.1 50.0 58.3 133.7 51.3 30.2 3.9 11.0 50.6 42.9 73.2 29.0 3.3 86.6 43.4 10.0 57.2 62.0 47.8 39.6 28.7 36.8 344.9 0.0 93.8 15.6 103.6 24.4 92.9 49.2 10.3 34.1 67.1 207.1 28.8 88.7 133.8 24.7 34.4 151.3 52.0 14.6 1.7 34.3 82.8 38.7 11.3 12.2 22.4 16.1 11.1 5.4 22.5 11.6 9.1 2.1 25.1 40.9 385.7 161.0 27.8 3.4 115.2 157.3 6.5 76.1 10.6 0.0 4.4 25.9 4.4 6.9 46.4 51.7 49.8 9.9 84.6 93.0 88.4 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1725.9;placenta: 2928.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2583.6;Fibroblasts: 562.6;Hepatocytes: 1012.4;Smooth muscle cells: 450.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 34405.9;HSkMC: 16044.5;hTERT-HME1: 9585.3;hTERT-RPE1: 10587.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" NA NA 47000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" 151.1 31.4 37.8 131.9 44.8 0.6 76.5 36.3 51.2 135.9 85.9 444.0 33.8 156.1 61.3 251.6 174.5 187.1 410.9 38.9 41.1 42.9 1725.9 785.7 37.3 37.7 39.8 110.0 26.0 19.3 26.2 2928.1 43.5 105.6 237.2 6.0 67.0 428.9 37.7 52.7 103.4 722.6 36.2 14.3 127.2 25.8 112.1 133.8 40.4 148.4 23.9 361.7 87.1 35.3 12.5 84.2 104.6 22.8 4456.5 34405.9 4.8 1799.2 1200.2 1765.3 1259.9 1059.2 43.7 1.2 9.7 6331.7 47.2 192.7 17.4 4220.9 946.9 1.0 7.4 0.8 24.7 3607.2 3192.2 1.2 6.6 16044.5 29.3 4136.5 9585.3 10587.1 2177.2 1.0 8.2 5.0 3673.9 17.0 2.9 1.5 52.7 2.4 15.2 1.0 2.4 8.0 47.4 13.7 6.0 25.0 213.7 116.4 1219.8 4649.5 19.4 3.2 4161.0 2553.1 269.9 2837.4 355.6 4.4 1.6 1.6 3161.2 1.0 694.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.8 44.8 36.3 51.2 38.9 41.1 37.7 39.8 43.5 36.2 112.1 35.3 138.9 67.3 67.8 13.4 2.3 55.1 4.1 227.0 2.2 6.4 4.2 5.2 36.3 30.0 34.0 16.5 0.0 216.6 2.3 3.4 0.0 6.5 1.8 6.5 265.8 215.4 21.0 16.8 9.5 9.8 2583.6 562.6 4.1 5.5 18.9 53.5 227.7 1012.4 365.2 1.7 8.1 10.2 12.2 38.0 73.7 4.6 186.4 85.9 110.3 101.2 1.2 1.9 0.0 11.6 10.7 12.5 1.4 88.4 1.7 17.8 0.0 0.6 23.1 8.7 72.3 401.5 450.2 1.6 7.8 5.0 37.4 205.8 11.3 8.5 23.7 1.7 FOXC1 "ARA, FKHL7, FREAC3, IGDA, IHG1, IRID1" ENSG00000054598 "Forkhead box C1" Q12948 6 1609915-1613897 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Deafness, Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "salivary gland: 154.4" "Cell type enhanced" "Detected in many" "Adipocytes: 93.7;Breast myoepithelial cells: 59.4;Endothelial cells: 64.7;Hepatic stellate cells: 65.7;Urothelial cells: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 92.4;HEK 293: 91.8;RPTEC TERT1: 35.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 18.0" HPA040670 Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA040670: AB_10673412" "unprognostic (2.65e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.53e-4)" "unprognostic (3.22e-2)" "unprognostic (3.22e-2)" "unprognostic (1.24e-1)" "unprognostic (3.30e-2)" "unprognostic (1.54e-2)" "unprognostic (4.04e-3)" "unprognostic (1.58e-1)" "unprognostic (2.33e-3)" "unprognostic (9.55e-2)" "unprognostic (1.11e-2)" "unprognostic (6.48e-2)" "unprognostic (2.04e-1)" "unprognostic (3.83e-3)" "unprognostic (3.74e-1)" 12.3 6.0 7.7 1.2 8.3 0.6 9.0 7.1 9.3 6.3 11.0 1.7 0.9 3.7 1.7 4.8 5.0 7.5 14.0 6.0 6.5 19.9 1.2 3.3 1.7 9.0 7.4 4.7 3.6 1.6 9.5 4.1 8.7 8.6 0.9 0.3 154.4 6.4 2.4 11.1 1.6 2.3 7.1 0.4 1.7 2.0 9.2 8.3 5.6 2.9 2.2 9.4 5.6 7.1 18.0 2.0 0.6 92.4 4.2 4.6 2.9 8.9 10.3 5.4 4.3 6.7 3.7 0.0 10.0 5.2 3.9 19.9 8.8 6.5 4.5 5.7 91.8 3.7 5.3 3.3 2.8 1.4 6.0 15.6 8.7 7.3 8.3 2.8 7.9 0.6 2.7 0.1 2.3 3.8 0.0 2.0 0.3 8.9 7.6 0.0 3.7 0.5 35.9 13.3 3.4 8.0 10.9 0.1 6.4 4.5 2.6 1.5 2.0 11.5 7.1 5.9 9.6 0.4 0.8 0.0 3.2 4.5 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.7 8.3 7.1 9.3 6.0 6.5 9.0 7.4 8.7 7.1 9.2 7.1 93.7 0.0 0.6 0.0 0.4 17.7 31.9 26.3 13.6 0.0 42.2 59.4 7.1 0.0 23.6 11.0 0.0 5.3 1.9 0.9 1.9 3.9 0.6 8.6 1.1 64.7 0.0 0.0 0.0 17.1 0.6 21.2 1.5 3.8 0.0 0.7 65.7 0.4 1.3 0.0 0.0 1.5 8.2 1.3 5.5 1.4 16.1 2.7 1.8 23.4 0.0 0.3 0.0 0.5 0.1 16.2 0.1 28.2 0.1 9.5 0.0 7.4 34.9 0.0 0.0 19.2 40.4 0.7 3.1 11.2 6.5 0.8 1.1 4.4 0.6 64.9 FOXC2 "FKHL14, MFH-1" ENSG00000176692 "Forkhead box C2" Q99958 16 86566829-86569728 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 5.6" "Group enriched" "Detected in some" 4 "Peritubular cells: 30.9;Sertoli cells: 19.7;Smooth muscle cells: 33.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 25.2;HUVEC TERT2: 19.5;LHCN-M2: 31.2;TIME: 36.0;U-138 MG: 18.4;U-2197: 31.5;U-87 MG: 24.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 6 "spinal cord: 42.7" HPA056302 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Nuclear bodies" "HPA056302: AB_2683093" "unprognostic (3.17e-2)" "unprognostic (1.76e-3)" "unprognostic (4.87e-2)" "unprognostic (4.32e-1)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (4.49e-2)" "unprognostic (1.15e-2)" "unprognostic (4.71e-2)" "unprognostic (8.88e-2)" "unprognostic (1.47e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.57e-7)" "unprognostic (1.12e-2)" "unprognostic (3.47e-2)" "unprognostic (2.43e-1)" "unprognostic (1.84e-4)" 2.4 1.5 0.5 0.3 1.1 0.0 1.8 0.9 1.6 2.2 3.2 0.5 0.1 0.8 0.6 0.5 2.0 1.3 5.6 0.4 0.4 5.4 0.1 2.1 0.4 0.5 0.5 1.1 0.2 0.1 2.4 0.1 0.5 1.0 0.1 0.1 2.4 0.6 0.7 0.8 0.4 0.4 0.7 0.0 0.4 1.9 0.7 0.1 2.0 0.5 0.1 0.8 1.5 0.3 0.0 0.0 0.0 0.0 5.8 7.8 0.0 11.3 14.3 8.0 1.5 0.0 0.0 0.0 1.5 1.4 11.2 0.0 0.2 3.3 7.0 0.0 0.6 0.0 7.9 0.0 2.7 0.0 0.0 1.3 3.4 25.2 7.9 14.5 19.5 0.0 0.0 0.0 31.2 0.0 0.0 0.0 0.0 0.5 0.1 0.0 1.7 0.0 0.1 0.1 0.0 0.0 1.8 0.0 0.0 5.9 0.0 0.0 36.0 18.4 0.0 31.5 0.0 0.0 0.0 0.0 24.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 0.9 1.6 0.4 0.4 0.5 0.5 0.5 0.7 0.7 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.0 0.8 2.1 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 5.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.5 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.6 1.5 0.1 1.8 1.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 30.9 1.2 0.8 0.0 0.0 0.0 0.1 19.7 0.6 33.2 0.2 5.0 0.5 0.0 0.0 0.0 0.0 0.1 1.4 FOXE3 "FKHL12, FREAC8" ENSG00000186790 "Forkhead box E3" Q13461 1 47416285-47418052 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Aortic aneurysm, Cataract, Disease variant, Peters anomaly" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "Cardiomyocytes: 6.0;Spermatogonia: 2.3" "Group enriched" "Detected in some" 4 "cervical cancer: 0.5;testis cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 18 "SuSa: 10.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 12: NES - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (2.11e-1)" "unprognostic (1.31e-2)" "unprognostic (1.23e-3)" "unprognostic (1.32e-1)" "unprognostic (1.71e-1)" "unprognostic (6.24e-2)" "unprognostic (1.24e-2)" "unprognostic (8.21e-2)" "unprognostic (1.49e-1)" "unprognostic (2.34e-1)" "unprognostic (5.15e-2)" "unprognostic (1.04e-1)" "unprognostic (2.39e-7)" "unprognostic (2.41e-1)" "unprognostic (5.46e-2)" "unprognostic (3.60e-1)" 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 2.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 FOXL2 "BPES, BPES1" ENSG00000183770 "Forkhead box L2" P58012 3 138944224-138947137 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 12.8;ovary: 44.8;parathyroid gland: 12.5" "Cell type enriched" "Detected in some" 4 "Granulosa cells: 208.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 4.9;fHDF/TERT166: 5.6;HEL: 8.1;hTCEpi: 7.1;K-562: 8.4;SiHa: 5.6;THP-1: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA069613 Enhanced Supported Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA069613: AB_2686160" "unprognostic (1.46e-1)" "unprognostic (3.28e-2)" "unprognostic (4.76e-3)" "unprognostic (2.05e-1)" "unprognostic (5.16e-4)" "unprognostic (3.55e-2)" "unprognostic (2.35e-3)" "unprognostic (5.08e-2)" "unprognostic (3.79e-2)" "unprognostic (2.19e-1)" "unprognostic (9.63e-8)" "unprognostic (2.16e-2)" "unprognostic (4.65e-1)" "unprognostic (2.90e-2)" "unprognostic (1.61e-2)" 0.0 2.6 1.0 0.0 0.8 0.0 0.0 0.6 0.8 12.8 0.3 0.0 0.0 7.3 0.4 0.0 11.9 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.8 0.8 44.8 0.1 12.5 10.0 0.1 0.8 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.8 0.8 0.0 0.0 0.7 1.2 0.0 0.0 0.1 0.0 0.0 2.1 0.7 4.9 1.8 0.2 3.4 0.0 0.0 1.4 0.1 0.0 0.4 0.0 0.0 0.3 0.0 2.2 5.6 0.2 1.1 0.0 0.0 0.1 0.0 0.0 8.1 0.9 0.0 0.0 0.1 0.0 0.0 7.1 0.0 0.0 1.1 0.0 0.0 8.4 0.0 2.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 5.6 0.0 0.0 0.3 0.0 5.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.6 0.8 0.6 0.6 0.8 0.8 0.8 0.8 1.2 0.7 0.2 0.0 0.0 0.0 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 41.8 1.6 0.0 0.0 0.0 0.2 0.3 20.9 0.0 1.0 0.0 208.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 6.2 1.8 1.4 0.0 1.0 0.0 0.3 48.4 0.0 0.0 FRAS1 "FLJ14927, FLJ22031, KIAA1500" ENSG00000138759 "Fraser extracellular matrix complex subunit 1" Q86XX4 4 78057323-78544269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.8;thyroid gland: 12.0" "Group enriched" "Detected in many" 9 "Excitatory neurons: 204.9;Inhibitory neurons: 377.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 35.9;Hep G2: 21.9;RH-30: 20.1;SiHa: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051601 Approved "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA051601: AB_2681547" "unprognostic (1.33e-2)" "unprognostic (1.04e-2)" "unprognostic (9.37e-2)" "unprognostic (8.91e-2)" "unprognostic (2.97e-1)" "unprognostic (2.04e-1)" "unprognostic (1.45e-3)" "unprognostic (2.02e-2)" "unprognostic (1.07e-1)" "unprognostic (2.69e-2)" "unprognostic (2.09e-2)" "unprognostic (4.02e-2)" "prognostic favorable (4.69e-4)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.78e-3)" "unprognostic (6.09e-2)" 2.0 0.6 3.4 0.5 5.8 0.0 0.7 0.0 7.9 2.1 4.0 3.5 0.3 2.0 1.9 1.7 1.0 0.9 1.5 3.5 3.3 7.4 0.3 3.4 0.1 3.1 3.3 0.2 5.4 0.6 2.4 5.8 3.0 2.3 1.3 2.2 1.0 0.7 2.7 1.3 1.0 1.4 0.6 0.7 0.9 0.6 13.8 2.6 12.0 2.2 0.2 0.5 1.4 4.9 4.6 6.9 2.7 0.0 7.0 2.9 4.8 1.1 4.1 0.6 0.4 5.4 9.8 0.0 8.2 35.9 0.0 1.3 3.8 2.1 0.1 0.0 3.8 4.2 8.5 21.9 0.8 0.0 0.0 14.1 2.3 0.0 5.2 5.4 0.1 0.3 0.0 0.0 4.1 0.2 0.1 0.0 8.6 3.6 1.3 0.0 20.1 0.0 8.7 9.9 5.0 9.7 21.6 6.7 1.3 12.3 0.0 0.0 0.0 0.0 4.5 2.9 1.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 5.8 0.0 7.9 3.5 3.3 3.1 3.3 3.0 0.6 13.8 4.9 0.5 32.1 0.0 9.1 0.1 1.9 2.2 2.5 10.2 10.8 0.8 1.8 7.3 22.8 9.2 29.5 0.0 28.0 0.0 0.8 3.9 7.6 2.1 5.5 1.0 2.0 1.2 0.0 204.9 1.7 1.4 5.3 4.1 13.5 0.0 0.1 1.1 0.2 4.4 0.0 377.7 1.0 0.0 0.0 0.7 2.8 0.6 0.4 1.8 20.6 0.0 0.6 0.0 10.1 5.5 2.7 2.5 0.0 0.0 1.8 1.4 4.3 2.5 2.7 0.0 1.5 3.4 0.8 1.2 10.4 1.3 15.6 0.1 2.8 2.4 0.4 FREM1 "C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR" ENSG00000164946 "FRAS1 related extracellular matrix 1" Q5H8C1 9 14737152-14910995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.4" "Group enriched" "Detected in many" 7 "Early spermatids: 73.7;Inhibitory neurons: 126.1;Late spermatids: 144.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HEL: 163.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA 58000 "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.13e-5)" "unprognostic (2.59e-3)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.66e-3)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (3.62e-2)" "unprognostic (6.23e-2)" "unprognostic (8.95e-13)" "unprognostic (2.28e-3)" "unprognostic (8.53e-2)" "unprognostic (3.41e-2)" "unprognostic (2.86e-1)" 5.3 2.5 0.9 0.8 1.1 0.2 4.8 4.2 1.3 5.0 2.0 6.4 2.1 19.7 36.4 1.0 4.1 3.7 6.4 1.1 1.3 17.0 0.9 2.4 0.0 2.0 1.3 1.4 6.6 5.0 1.0 5.5 1.2 1.1 1.7 1.3 0.8 3.4 0.9 3.3 5.4 14.2 3.0 0.4 1.0 4.2 1.2 1.2 0.7 0.8 0.5 2.1 2.3 3.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.8 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.4 3.7 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 4.2 1.3 1.1 1.3 2.0 1.3 1.2 3.0 1.2 3.8 0.4 0.0 0.6 13.1 0.3 1.3 0.2 0.0 0.6 2.0 0.1 0.1 2.9 2.8 0.0 1.8 0.0 0.5 0.0 0.2 0.0 0.3 73.7 1.5 7.7 0.4 0.0 3.0 16.2 0.0 0.3 11.2 0.5 1.3 5.1 0.2 3.9 0.0 0.5 0.0 126.1 2.4 0.0 0.6 1.2 144.7 0.6 0.1 0.0 6.5 0.6 4.0 0.0 7.1 4.3 0.2 0.0 1.5 0.0 0.1 13.0 1.3 0.0 0.1 0.0 0.6 2.8 0.8 0.9 0.0 1.1 0.3 0.1 6.1 4.7 0.1 FREM2 DKFZp686J0811 ENSG00000150893 "FRAS1 related extracellular matrix 2" Q5SZK8 13 38687077-38887131 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 7.7;thyroid gland: 4.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 27.2;Astrocytes: 46.0;Cholangiocytes: 15.7;Endometrial ciliated cells: 18.6;Glandular and luminal cells: 48.6;Oligodendrocyte precursor cells: 15.6;Proximal tubular cells: 24.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 15.5;HAP1: 10.6;MCF7: 7.8;RT4: 7.2;SK-BR-3: 6.3;SuSa: 29.7;WM-115: 5.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA028831 Uncertain Approved Cytosol NA NA 1500000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" Cytosol "HPA028831: AB_10603668" "unprognostic (1.71e-2)" "unprognostic (3.72e-1)" "unprognostic (1.92e-1)" "unprognostic (1.10e-1)" "unprognostic (4.69e-1)" "unprognostic (6.24e-2)" "unprognostic (1.62e-1)" "unprognostic (8.42e-3)" "unprognostic (8.54e-2)" "unprognostic (1.64e-3)" "unprognostic (4.25e-1)" "unprognostic (2.54e-1)" "prognostic favorable (2.23e-7)" "unprognostic (7.21e-2)" "unprognostic (1.40e-1)" "unprognostic (9.92e-2)" "unprognostic (3.14e-1)" 0.2 0.1 0.3 0.0 1.1 0.0 0.2 0.2 0.9 0.3 0.1 0.5 0.1 0.5 0.2 0.0 0.4 0.8 0.0 0.6 0.0 7.7 2.0 2.2 0.0 0.0 0.4 0.7 2.7 0.0 0.3 1.4 0.0 1.8 0.1 0.3 0.0 0.7 2.8 0.1 0.2 0.3 0.0 0.1 0.9 0.3 0.0 0.2 4.9 3.6 0.0 0.2 0.0 0.0 0.0 0.0 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 10.6 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 2.3 0.0 0.2 0.0 1.4 0.1 2.3 7.2 0.2 0.1 0.0 6.3 0.3 29.7 1.1 0.0 0.0 0.0 0.8 0.0 1.6 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.2 0.9 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 27.2 46.0 0.0 0.6 0.1 0.7 0.0 0.2 0.4 0.5 2.7 15.7 1.4 1.8 0.0 5.9 0.0 0.3 5.9 3.2 0.5 18.6 4.5 0.6 0.0 0.0 0.5 0.2 0.4 0.4 0.0 48.6 0.0 0.5 0.0 1.3 0.8 0.0 9.1 0.1 2.0 0.3 0.0 0.1 0.0 0.2 0.0 3.7 0.0 3.3 0.0 15.6 9.7 1.0 0.1 0.0 0.0 0.0 0.0 24.8 2.9 0.3 0.0 3.1 0.7 0.2 0.9 0.0 0.1 1.9 0.5 2.9 0.1 0.1 FRMD4A "bA295P9.4, FLJ10210, FRMD4, KIAA1294" ENSG00000151474 "FERM domain containing 4A" Q9P2Q2 10 13643706-14462142 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 60.8" "Group enriched" "Detected in many" 7 "Excitatory neurons: 1527.6;Inhibitory neurons: 1622.8;Microglial cells: 1329.4;Oligodendrocyte precursor cells: 442.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.3" "Lineage enriched" "Detected in single" 5 "B-cells: 2.3" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 134.0;HUVEC TERT2: 105.8;TIME: 191.6;WM-115: 163.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038449 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoplasm "HPA038449: AB_10669539" "unprognostic (6.77e-2)" "unprognostic (1.57e-1)" "unprognostic (1.51e-3)" "unprognostic (5.68e-2)" "unprognostic (1.55e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.21e-3)" "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (9.20e-2)" "unprognostic (1.14e-1)" "unprognostic (1.19e-2)" "unprognostic (1.67e-1)" "unprognostic (1.25e-1)" "unprognostic (8.16e-2)" "unprognostic (1.84e-1)" 60.8 5.2 38.9 11.7 28.1 5.4 18.7 0.0 29.2 8.6 0.0 13.1 5.7 5.7 4.0 9.4 8.8 9.6 16.7 24.1 8.5 19.5 12.2 14.2 9.1 15.6 10.9 6.8 15.5 2.4 8.7 22.5 6.2 10.3 6.4 14.1 13.6 10.2 8.1 32.0 7.4 6.5 10.0 32.8 7.9 8.8 14.4 15.6 8.1 7.3 8.4 10.4 8.9 18.9 7.0 7.1 90.1 0.5 12.3 22.0 16.9 40.8 36.5 35.2 48.7 12.1 4.2 0.1 28.3 21.5 48.6 13.5 0.3 3.3 30.7 0.3 9.9 1.4 0.9 0.2 11.0 0.5 1.1 12.8 3.2 134.0 16.4 98.9 105.8 3.1 13.6 0.4 64.7 8.5 4.6 0.8 24.6 0.3 9.6 0.4 30.8 0.2 16.6 5.8 4.3 15.9 0.2 32.7 64.4 16.1 18.5 3.3 191.6 48.8 17.4 47.6 49.3 0.3 0.4 0.3 41.7 1.0 163.4 0.1 0.1 0.0 0.0 0.1 0.1 0.8 0.3 0.1 0.0 2.3 0.3 0.0 0.3 0.2 0.0 0.4 0.4 0.0 38.9 28.1 0.0 29.2 24.1 8.5 15.6 10.9 6.2 10.0 14.4 18.9 48.6 32.1 2.6 168.1 1.7 35.1 13.1 3.0 9.1 54.2 17.1 14.4 11.4 45.8 4.1 33.1 18.8 69.6 0.4 1.1 11.7 15.8 42.5 13.1 5.5 44.0 4.8 81.7 1527.6 4.0 42.1 14.9 4.6 26.9 15.2 58.1 44.3 6.2 35.9 80.8 1622.8 3.4 6.1 95.6 19.9 98.8 2.1 25.5 16.0 1329.4 2.7 46.0 0.0 442.3 61.0 1.8 1.4 1.9 0.9 8.0 0.3 2.7 2.5 12.9 13.1 41.2 45.5 1.3 2.1 20.6 32.7 28.7 3.0 5.3 5.4 4.3 FTO "ALKBH9, KIAA1752, MGC5149" ENSG00000140718 "FTO alpha-ketoglutarate dependent dioxygenase" Q9C0B1 16 53701692-54158512 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 173.3;Excitatory neurons: 226.1;Inhibitory neurons: 240.7;Oligodendrocyte precursor cells: 210.6;Oligodendrocytes: 282.5;Respiratory ciliated cells: 182.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017123, HPA041086, HPA068695" Enhanced Supported Vesicles,Cytosol No No 540000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Vesicles "CAB017123: , HPA041086: AB_2677293, HPA068695: AB_2732117" "unprognostic (9.74e-2)" "unprognostic (2.49e-1)" "unprognostic (9.30e-2)" "unprognostic (1.24e-2)" "unprognostic (1.81e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (1.41e-1)" "unprognostic (8.67e-2)" "unprognostic (1.02e-1)" "unprognostic (3.88e-2)" "unprognostic (6.80e-2)" "unprognostic (1.44e-1)" "unprognostic (5.81e-3)" "unprognostic (1.78e-1)" "unprognostic (4.30e-3)" "unprognostic (6.11e-3)" 24.4 33.6 31.8 12.5 36.6 8.2 36.3 30.1 37.7 25.8 31.0 22.2 7.7 26.9 21.4 17.2 25.3 21.6 27.1 35.2 39.5 25.0 17.4 36.8 15.0 29.2 31.3 27.2 20.7 40.6 26.2 20.1 31.9 20.0 14.1 38.4 18.9 23.9 33.1 21.4 12.5 29.9 30.5 16.4 15.0 8.3 33.8 17.0 27.5 23.0 14.8 21.9 18.5 43.9 15.1 26.8 35.0 35.9 67.3 50.4 11.5 35.6 32.2 29.3 8.5 16.8 19.3 34.4 38.2 46.3 16.6 21.7 32.4 34.9 42.5 16.0 25.5 15.5 33.6 31.7 46.2 12.5 17.1 55.9 36.5 26.6 32.5 36.6 44.1 25.1 15.2 8.4 48.1 11.8 28.0 19.2 18.1 15.5 17.5 42.2 52.9 32.3 44.6 12.3 43.0 29.7 40.4 23.6 10.8 33.7 31.1 29.3 42.4 36.4 23.9 19.8 22.1 15.9 13.9 35.0 33.9 22.9 28.7 14.9 17.9 9.7 25.6 22.7 32.4 17.6 24.4 25.9 23.8 17.4 22.5 24.4 2.9 26.4 16.5 9.5 26.6 23.1 31.8 36.6 30.1 37.7 35.2 39.5 29.2 31.3 31.9 30.5 33.8 43.9 15.1 80.1 62.0 173.3 10.3 12.4 10.0 8.6 13.6 22.8 69.1 39.5 22.3 15.7 54.4 7.3 12.5 9.3 10.2 4.8 7.9 9.0 39.1 11.0 18.3 17.4 6.6 9.7 226.1 5.7 7.4 23.1 9.7 9.9 25.9 16.8 11.0 13.8 9.2 16.8 240.7 6.6 10.2 9.0 13.2 69.9 14.3 11.8 10.6 134.0 5.5 19.6 10.3 210.6 282.5 5.5 5.0 15.1 18.7 6.0 4.5 15.8 182.7 14.1 13.1 21.6 16.8 3.5 3.4 11.0 9.1 5.1 12.9 17.8 6.3 7.9 FZD2 ENSG00000180340 "Frizzled class receptor 2" Q14332 17 44557484-44561262 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 10.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Kupffer cells: 9.8;Leydig cells: 23.3;Peritubular cells: 18.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;myeloid DC: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;monocytes: 1.1" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 53.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057667 Uncertain Approved "Nucleoplasm,Nuclear bodies,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "Cell Junctions" "HPA057667: AB_2683497" "unprognostic (6.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.04e-2)" "unprognostic (8.83e-3)" "unprognostic (2.04e-1)" "unprognostic (5.29e-3)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (9.45e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-2)" "unprognostic (1.86e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-2)" "unprognostic (6.35e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-3)" 1.5 1.6 1.0 1.4 1.5 0.2 1.3 0.9 1.2 5.9 10.5 1.8 0.9 5.3 1.3 0.9 3.8 1.8 2.8 1.1 1.3 2.8 0.2 2.9 0.8 1.3 1.9 3.3 1.5 2.1 1.1 3.6 2.0 1.7 0.4 0.7 1.0 1.9 0.4 0.6 1.6 1.5 1.3 2.1 1.2 1.5 1.4 0.3 2.4 0.7 0.7 2.0 2.5 1.6 12.9 37.7 38.3 13.8 8.7 6.4 0.4 39.5 30.4 53.4 38.2 28.4 6.2 0.0 8.9 13.9 13.1 5.5 3.6 2.8 30.2 2.9 7.2 1.7 6.6 0.1 7.7 0.2 7.5 10.7 2.8 9.6 8.8 40.8 1.8 4.9 2.5 0.3 20.9 5.9 6.7 3.6 26.8 0.1 6.7 18.1 8.6 1.9 7.7 0.6 3.8 10.9 5.2 1.1 2.3 32.4 14.6 8.4 0.7 24.1 17.5 4.4 22.6 0.8 0.7 3.0 4.0 2.4 11.3 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.2 1.0 1.5 0.9 1.2 1.1 1.3 1.3 1.9 2.0 1.3 1.4 1.6 0.5 19.2 0.0 1.6 0.6 0.6 0.3 0.9 0.0 0.0 0.9 2.9 1.9 0.0 0.2 1.8 0.0 1.6 1.8 0.0 0.0 0.3 0.6 1.1 8.4 0.7 1.2 1.3 0.0 1.8 0.5 5.9 0.0 1.5 0.0 1.4 0.7 0.0 4.8 0.0 0.0 0.3 0.0 9.8 6.0 0.4 23.3 5.6 0.0 6.5 6.2 6.0 0.0 0.0 0.2 0.7 0.0 18.0 0.3 0.1 0.0 0.3 0.2 0.4 0.0 0.4 5.3 0.3 1.2 0.3 0.4 2.3 0.2 2.4 0.0 0.0 G6PC3 UGRP ENSG00000141349 "Glucose-6-phosphatase catalytic subunit 3" Q9BUM1 17 44070735-44076344 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067052 Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA067052: AB_2685771" "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" "unprognostic (3.61e-1)" "prognostic favorable (1.11e-4)" "unprognostic (1.88e-3)" "unprognostic (3.16e-1)" "prognostic unfavorable (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (2.43e-1)" "unprognostic (1.15e-2)" "unprognostic (2.59e-2)" "unprognostic (1.85e-3)" "unprognostic (1.87e-3)" "unprognostic (4.53e-2)" "unprognostic (3.06e-2)" "unprognostic (2.35e-1)" "unprognostic (4.49e-2)" 56.7 97.2 64.8 22.5 67.8 16.0 55.6 70.5 79.3 47.6 88.8 42.1 28.7 55.4 63.9 37.1 45.6 23.9 61.9 65.3 77.5 75.2 26.4 42.9 19.3 74.9 86.9 44.3 56.5 66.7 95.1 25.8 96.1 59.5 18.2 17.1 48.7 40.6 54.3 26.8 39.6 23.0 67.9 45.2 51.4 55.1 72.7 15.2 71.1 26.4 12.0 48.7 37.7 72.4 40.0 231.7 73.7 128.5 77.9 58.3 55.3 45.0 86.9 96.2 64.4 97.1 62.3 88.9 62.8 95.1 65.4 67.4 53.5 92.1 44.5 46.4 86.0 49.3 142.5 182.4 84.1 46.1 59.8 77.3 44.3 93.1 62.3 59.6 79.3 35.9 51.5 109.6 72.5 112.1 22.4 71.4 99.3 48.7 133.5 45.6 48.4 207.5 137.6 93.6 92.7 83.0 49.1 57.4 59.3 82.9 158.6 45.1 87.6 98.8 53.1 26.8 63.5 74.0 56.2 26.1 110.3 38.2 128.9 3.0 33.1 7.9 9.9 43.4 12.1 12.1 8.0 9.1 54.2 13.9 9.7 12.9 1.4 17.5 26.3 74.5 8.5 16.9 64.8 67.8 70.5 79.3 65.3 77.5 74.9 86.9 96.1 67.9 72.7 72.4 22.3 3.2 12.9 5.2 10.4 2.5 17.3 31.8 8.0 10.5 20.7 21.5 6.4 21.5 25.2 40.5 12.5 64.3 17.1 12.4 13.7 59.3 5.0 18.9 22.1 26.0 22.9 9.7 2.8 49.4 41.1 25.0 16.8 20.1 18.3 20.2 18.5 7.1 58.7 5.0 4.5 14.1 24.4 21.6 12.2 6.2 20.2 20.9 14.2 0.0 21.8 30.7 10.3 8.0 5.5 33.6 13.6 23.0 27.2 19.5 20.5 36.0 24.6 8.3 13.1 15.3 21.4 31.5 26.7 14.3 2.6 42.5 7.0 43.9 19.7 17.2 GANAB "G2AN, GIIA, GluII, KIAA0088" ENSG00000089597 "Glucosidase II alpha subunit" Q14697 11 62624826-62646726 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026874, HPA061426" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 23000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA026874: AB_1849745, HPA061426: AB_2684516" "unprognostic (2.12e-1)" "unprognostic (5.95e-3)" "unprognostic (4.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-2)" "unprognostic (3.65e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (5.80e-3)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-3)" "unprognostic (5.91e-2)" "unprognostic (1.01e-3)" "unprognostic (3.81e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.54e-4)" 93.9 73.7 31.8 88.2 34.5 83.7 92.8 36.6 36.7 112.6 51.6 104.7 95.6 102.1 151.7 66.4 106.9 75.3 67.9 31.7 41.2 98.5 171.7 86.8 81.7 38.5 34.9 115.5 88.1 130.6 21.8 141.8 38.1 97.5 116.8 79.4 101.8 111.1 39.4 74.7 90.5 126.0 36.5 86.7 85.2 66.1 39.8 105.2 132.6 53.0 94.8 90.7 34.2 43.4 298.2 245.9 318.2 552.0 464.1 389.0 332.9 312.4 480.4 436.2 362.1 222.2 515.9 201.2 616.0 572.5 337.8 376.4 375.2 376.7 443.8 155.8 191.3 202.9 317.8 125.6 389.0 325.7 248.7 397.2 248.4 433.6 475.3 533.0 422.3 199.6 278.5 352.9 398.2 313.6 167.6 193.4 262.3 236.6 237.7 209.5 368.7 513.1 285.7 230.3 168.6 221.2 451.1 308.2 370.8 321.6 380.9 304.8 311.6 430.0 272.2 342.9 309.9 360.8 423.8 152.2 473.9 173.1 421.7 23.9 19.3 19.1 23.8 23.4 23.1 15.9 17.2 20.0 20.8 14.9 20.9 21.3 8.9 29.8 22.2 18.4 17.3 22.6 31.8 34.5 36.6 36.7 31.7 41.2 38.5 34.9 38.1 36.5 39.8 43.4 42.7 12.8 20.7 17.3 29.8 28.3 29.4 45.8 13.6 31.4 57.4 53.8 7.8 52.9 24.2 68.0 60.5 81.7 33.4 40.1 5.9 47.0 18.5 31.4 59.1 42.2 31.8 25.0 12.6 42.6 137.3 45.9 27.5 46.5 11.4 72.8 48.2 98.0 57.9 35.3 16.0 48.9 34.6 45.8 25.1 16.4 58.4 32.7 35.6 15.9 38.9 36.5 38.1 11.1 16.5 39.5 29.3 68.1 50.4 34.0 47.8 27.0 26.3 41.4 32.9 36.4 34.7 25.3 47.4 21.2 31.3 80.2 25.2 63.1 56.3 32.4 GATA3 HDR ENSG00000107485 "GATA binding protein 3" P23771 10 8045378-8075198 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 109.9;skin 1: 172.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 267.1;Cytotrophoblasts: 323.5;Extravillous trophoblasts: 746.6;Suprabasal keratinocytes: 198.9;Syncytiotrophoblasts: 1134.9" "Group enriched" "Detected in many" 24 "breast cancer: 190.0;urothelial cancer: 87.0" "Group enriched" "Detected in many" 5 "midbrain: 28.3;pons: 12.6" "Group enriched" "Detected in many" 41 "gdT-cell: 19.9;MAIT T-cell: 26.9;memory CD4 T-cell: 36.7;memory CD8 T-cell: 28.8;naive CD4 T-cell: 19.9;naive CD8 T-cell: 18.3;NK-cell: 36.1;T-reg: 43.6" "Group enriched" "Detected in many" 57 "NK-cells: 36.1;T-cells: 43.6" "Cell line enhanced" "Detected in many" "BEWO: 190.2;MCF7: 473.4;RT4: 194.3;SH-SY5Y: 161.2;T-47d: 605.2" "Region enriched" "Detected in single" 6 "midbrain: 6.1" "Group enriched" "Detected in some" 11 "medulla oblongata: 5.2;midbrain: 14.0;pons: 11.8;thalamus: 13.1" "CAB016217, HPA029730" Enhanced Supported Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "CAB016217: AB_2108591, HPA029730: AB_10601907" "unprognostic (1.70e-1)" "unprognostic (7.23e-2)" "unprognostic (3.58e-2)" "unprognostic (2.00e-1)" "unprognostic (7.03e-3)" "unprognostic (4.68e-3)" "unprognostic (4.23e-2)" "unprognostic (9.65e-2)" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (3.83e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (6.31e-2)" "unprognostic (1.82e-3)" 6.7 6.4 0.9 3.8 0.2 4.1 34.2 0.2 0.2 3.4 0.8 0.7 1.0 0.6 8.6 0.6 0.5 1.2 2.5 0.1 0.6 24.9 1.0 3.4 7.8 3.9 28.3 0.1 0.3 109.9 5.0 32.2 12.6 11.2 0.7 0.0 19.9 24.9 2.1 172.9 2.4 0.3 0.5 7.2 1.5 0.2 4.1 25.0 3.0 1.0 3.8 38.8 10.8 0.2 33.8 8.1 0.0 0.4 0.0 0.0 190.2 0.7 0.0 0.0 0.1 12.4 29.9 0.0 0.1 0.0 0.0 28.9 3.2 0.6 0.1 95.8 10.2 0.2 0.3 0.1 2.1 0.1 0.5 0.0 6.9 0.1 1.8 1.0 15.3 45.8 0.4 0.0 0.1 473.4 54.2 0.5 3.5 6.5 4.5 2.8 2.6 0.8 0.0 194.3 9.8 161.2 0.5 26.8 0.0 34.1 605.2 0.1 0.0 2.4 5.9 1.4 4.3 0.9 0.0 0.0 1.3 0.0 1.7 0.1 0.1 0.0 19.9 0.0 26.9 0.4 36.7 28.8 0.0 0.1 19.9 18.3 0.7 36.1 0.0 0.0 43.6 7.0 0.9 0.2 0.2 0.2 0.1 0.6 3.9 28.3 12.6 0.5 4.1 0.2 14.6 0.0 6.0 0.0 3.4 94.8 69.6 1.6 0.0 0.0 267.1 167.3 1.3 0.0 1.5 178.4 0.0 323.5 49.2 0.0 0.0 0.2 0.2 0.5 0.4 12.6 0.0 2.1 0.0 0.4 746.6 5.3 2.6 0.7 2.5 0.0 6.8 0.6 30.7 0.0 0.0 0.0 0.0 3.5 9.9 0.1 0.0 3.8 8.8 1.0 1.5 0.0 51.5 0.0 0.0 4.1 1.1 0.0 12.2 45.8 0.0 0.6 0.3 0.0 0.0 1.1 2.8 0.0 1.4 1.0 198.9 1134.9 93.4 0.5 0.0 106.1 GATA4 ENSG00000136574 "GATA binding protein 4" P43694 8 11676959-11760002 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 88.6;ovary: 95.4;pancreas: 53.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 41.4;Exocrine glandular cells: 33.7;Gastric mucus-secreting cells: 61.2;Granulosa cells: 158.4;Hepatic stellate cells: 57.8;Late spermatids: 37.0;Leydig cells: 41.3;Peritubular cells: 41.3;Theca cells: 80.1" "Cancer enhanced" "Detected in many" "stomach cancer: 21.8;testis cancer: 12.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 19.7;HHSteC: 20.9;OE19: 6.2;SH-SY5Y: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013125, HPA073899" Uncertain Supported "Nuclear bodies" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies" "CAB013125: AB_2533804, HPA073899: AB_2686641" "unprognostic (2.99e-2)" "unprognostic (1.59e-1)" "unprognostic (2.36e-1)" "unprognostic (8.68e-4)" "unprognostic (2.66e-3)" "unprognostic (1.71e-1)" "unprognostic (8.55e-3)" "unprognostic (1.02e-2)" "unprognostic (5.47e-2)" "unprognostic (2.55e-1)" "unprognostic (2.78e-2)" "unprognostic (2.49e-1)" "unprognostic (1.67e-8)" "unprognostic (1.09e-1)" "unprognostic (1.61e-1)" "unprognostic (1.29e-2)" 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 20.2 0.2 0.0 0.0 2.3 4.0 88.6 0.0 0.0 0.0 36.6 0.2 0.0 0.0 0.0 95.4 53.5 0.0 0.1 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.1 35.2 32.4 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 19.7 20.9 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.2 0.0 0.0 0.2 1.3 0.0 0.0 1.5 20.5 0.0 0.0 0.1 3.9 1.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.4 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.2 16.1 0.0 0.1 6.1 0.0 0.0 0.1 33.7 0.2 12.0 61.2 0.0 0.0 158.4 57.8 12.1 0.6 0.0 0.1 0.8 0.0 2.8 0.0 37.0 41.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 14.5 0.0 41.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 5.3 2.4 2.2 0.0 0.0 0.8 0.1 80.1 0.9 0.0 GATA5 "bB379O24.1, GATAS" ENSG00000130700 "GATA binding protein 5" Q9BWX5 20 62463497-62475995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.2;testis: 11.5;urinary bladder: 15.4" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 22.4;Hepatic stellate cells: 7.9;Intestinal goblet cells: 8.7;Proximal enterocytes: 38.8" "Cancer enhanced" "Detected in many" "stomach cancer: 5.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.4;HEL: 2.9;K-562: 4.6;SiHa: 2.0;T-47d: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA067583 Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Cytosol "HPA067583: AB_2685867" "unprognostic (2.21e-1)" "unprognostic (2.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.10e-2)" "unprognostic (2.66e-1)" "unprognostic (2.39e-1)" "unprognostic (2.62e-1)" "unprognostic (8.34e-2)" "unprognostic (1.69e-2)" "unprognostic (5.70e-2)" "unprognostic (1.27e-2)" "unprognostic (7.96e-3)" "unprognostic (2.00e-2)" "unprognostic (1.04e-1)" "unprognostic (2.36e-2)" "unprognostic (5.39e-3)" 2.4 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.2 0.2 11.2 3.5 0.3 0.1 9.5 1.4 2.8 0.0 0.0 4.0 0.7 1.9 0.0 0.0 0.0 0.7 0.1 3.4 0.4 0.4 0.0 5.4 0.0 0.0 0.3 0.3 0.0 0.2 10.0 0.7 0.0 0.0 10.9 11.5 0.0 0.0 0.6 0.2 0.0 15.4 1.6 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 2.0 0.0 0.0 0.8 4.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.2 1.7 22.4 0.2 0.0 0.0 7.9 0.0 0.3 0.0 0.0 8.7 0.0 0.0 0.3 2.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.0 38.8 0.0 0.0 0.0 0.0 0.0 0.4 0.5 1.1 0.0 0.1 0.0 0.0 0.0 3.4 0.0 GATA6 ENSG00000141448 "GATA binding protein 6" Q92908 18 22169589-22202528 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 57.8;ovary: 73.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 97.6;Gastric mucus-secreting cells: 100.9;Granulosa cells: 52.9" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 23 "basophil: 4.0" "Lineage enriched" "Detected in single" 23 "granulocytes: 4.0" "Cell line enhanced" "Detected in many" "BEWO: 54.8;CACO-2: 69.7;hTERT-RPE1: 25.5;OE19: 37.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB011581, HPA066629" Approved Supported Nucleoplasm Yes No "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB011581: AB_732529, HPA066629: AB_2685695" "unprognostic (1.90e-1)" "unprognostic (1.14e-1)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (2.16e-1)" "unprognostic (9.43e-2)" "unprognostic (4.36e-2)" "unprognostic (3.47e-1)" "unprognostic (2.61e-1)" "unprognostic (8.45e-3)" "prognostic unfavorable (1.92e-9)" "unprognostic (8.75e-3)" "unprognostic (2.07e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-2)" 22.2 57.8 0.0 2.5 0.2 0.0 3.8 0.0 0.3 4.9 2.8 11.4 22.8 19.8 1.2 0.8 28.9 11.1 43.9 0.1 0.0 3.0 12.6 14.8 1.9 0.1 0.0 73.0 22.7 0.3 0.6 6.5 0.0 5.5 11.0 0.1 0.8 0.7 0.8 1.5 20.7 9.5 0.2 15.0 49.6 6.3 0.1 0.4 5.3 0.6 0.2 23.0 3.2 0.0 10.1 1.4 0.0 0.0 2.1 1.0 54.8 0.3 0.4 0.8 1.0 69.7 3.8 0.0 3.2 1.2 3.4 10.8 0.4 4.5 1.4 0.0 13.6 0.0 4.3 6.1 14.3 0.6 0.6 0.4 8.9 12.1 9.1 25.5 9.5 0.0 0.5 0.0 0.0 1.5 0.0 0.2 0.1 37.6 9.8 0.0 1.1 0.2 0.4 2.8 0.9 0.1 10.7 6.1 3.0 2.7 1.7 0.0 0.7 1.4 1.6 11.4 1.7 0.0 0.0 0.0 6.2 0.3 9.9 4.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 7.3 44.8 30.2 0.0 0.0 0.9 4.0 4.6 1.8 0.0 3.4 2.7 97.6 30.0 6.1 0.0 0.0 0.9 0.9 50.0 0.0 28.4 44.7 6.3 6.3 11.5 26.0 2.7 0.1 19.6 11.2 24.4 100.9 16.6 5.1 52.9 28.5 11.1 1.6 0.0 0.1 45.8 2.0 0.6 0.9 8.8 3.4 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.2 36.8 27.7 10.1 0.2 4.1 43.3 0.0 3.9 0.0 32.9 0.4 8.6 1.4 1.4 0.9 0.9 1.9 1.3 11.4 47.2 2.9 GDF1 ENSG00000130283 "Growth differentiation factor 1" P27539 19 18868545-18896158 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.7;pituitary gland: 1.5;skeletal muscle: 3.9;testis: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.8;SH-SY5Y: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 38: EFO-21 - Unknown function" 0.0 0.1 1.5 0.0 2.1 0.0 0.1 1.4 3.6 0.3 0.5 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.6 1.7 1.1 0.0 0.0 0.0 0.0 3.0 2.0 0.4 0.1 0.0 1.5 0.0 2.3 0.2 0.0 0.0 0.1 0.0 3.9 0.0 0.1 0.0 1.9 0.0 0.2 4.9 3.7 0.0 0.1 0.0 0.0 0.3 0.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.1 1.4 3.6 1.7 1.1 3.0 2.0 2.3 1.9 3.7 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GDF2 "BMP-9, BMP9" ENSG00000263761 "Growth differentiation factor 2" Q9UK05 10 47322454-47327588 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Angiogenesis "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "liver: 18.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB023357 Uncertain "Secreted to blood" NA NA 2210000 740000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 43: Cardiomyocytes - Nuclear processes" "CAB023357: AB_2111086" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GDF3 ENSG00000184344 "Growth differentiation factor 3" Q9NR23 12 7689784-7695775 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "kidney: 2.9" "Cell type enriched" "Detected in some" 25 "Granulosa cells: 30.2" "Cancer enriched" "Detected in some" 422 "testis cancer: 383.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "NTERA-2: 452.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA018468 Uncertain "Secreted to blood" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" "HPA018468: AB_1849586" "unprognostic (9.48e-2)" "unprognostic (3.90e-2)" "unprognostic (3.30e-2)" "unprognostic (1.86e-2)" "unprognostic (3.51e-1)" "unprognostic (5.40e-2)" "unprognostic (3.09e-1)" "unprognostic (2.08e-1)" "unprognostic (2.89e-1)" "unprognostic (1.07e-1)" "unprognostic (9.20e-2)" "unprognostic (1.25e-3)" "unprognostic (8.00e-3)" "unprognostic (1.00e-1)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 2.9 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.9 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.6 2.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.0 0.1 0.0 452.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 77.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GDF5 "BMP14, CDMP1" ENSG00000125965 "Growth differentiation factor 5" P43026 20 35433347-35454746 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Chondrogenesis "Cytokine, Growth factor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "salivary gland: 9.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.2;Basal prostatic cells: 1.0;granulocytes: 1.3" "Cancer enriched" "Detected in single" 7 "endometrial cancer: 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 17.6;BJ hTERT+: 5.4;GAMG: 9.4;HHSteC: 5.8;HSkMC: 14.4;U-87 MG: 6.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA015648 Uncertain "Secreted to blood" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "HPA015648: AB_1849589" "unprognostic (4.59e-3)" "unprognostic (3.48e-2)" "unprognostic (5.53e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (4.64e-1)" "unprognostic (2.17e-3)" "unprognostic (4.38e-2)" "unprognostic (1.40e-1)" "unprognostic (8.02e-2)" "unprognostic (2.77e-1)" "unprognostic (5.57e-3)" "unprognostic (2.13e-2)" "unprognostic (1.24e-1)" "unprognostic (1.38e-1)" "unprognostic (8.96e-3)" 0.9 0.1 0.1 0.0 0.4 0.0 0.6 0.1 0.3 0.3 0.3 1.6 0.0 0.4 0.1 0.0 0.1 0.2 0.4 0.1 0.2 0.3 0.0 2.3 0.0 0.2 0.1 0.0 0.0 0.0 1.7 0.0 0.2 0.9 0.1 0.0 9.9 1.2 0.1 0.1 0.1 0.6 0.1 0.0 0.1 0.6 0.4 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 1.3 17.6 0.1 2.8 5.4 0.4 1.0 0.0 0.0 0.0 0.0 4.5 9.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 5.8 0.0 0.0 14.4 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 3.2 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.4 0.2 0.1 0.0 2.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 1.9;Excitatory neurons: 1.6;Fibroblasts: 3.1;Oligodendrocyte precursor cells: 7.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 20.4;LHCN-M2: 33.1;SuSa: 15.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" 1.3 0.1 0.3 0.9 0.3 0.0 0.4 0.4 0.8 0.2 0.0 0.7 0.3 1.4 0.4 0.4 0.5 2.4 2.8 0.3 0.4 0.2 0.4 0.2 0.1 0.8 0.4 0.1 0.7 0.1 0.1 10.9 1.0 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.9 1.1 0.4 0.0 0.6 0.6 0.8 0.1 0.6 0.0 0.0 0.8 0.9 0.4 0.0 0.0 0.2 0.0 1.1 0.6 3.9 2.6 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 3.2 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 3.0 0.0 20.4 0.2 0.0 0.0 0.0 33.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.4 0.8 0.3 0.4 0.8 0.4 1.0 0.4 0.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.8 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.0 2.4 0.0 0.0 0.3 0.1 0.0 0.0 0.1 GDNF "ATF1, ATF2, HFB1-GDNF" ENSG00000168621 "Glial cell derived neurotrophic factor" P39905 5 37812677-37840041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes, Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8.2;skeletal muscle: 10.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 3.3;Skeletal myocytes: 11.5;Spermatogonia: 3.4;Theca cells: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 41.4;SuSa: 12.6;U-87 MG: 12.6;WM-115: 46.5" "Region enhanced" "Detected in single" "basal ganglia: 2.8" "Low region specificity" "Detected in some" "CAB005210, HPA070283" Supported Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" Vesicles Nucleoplasm "CAB005210: AB_2247684, HPA070283: AB_2686246" "unprognostic (1.08e-1)" "unprognostic (6.30e-2)" "unprognostic (3.54e-2)" "unprognostic (8.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (5.33e-2)" "unprognostic (1.92e-1)" "unprognostic (3.71e-2)" "unprognostic (2.01e-2)" "unprognostic (2.41e-1)" "unprognostic (2.10e-1)" "unprognostic (1.16e-4)" "unprognostic (2.04e-1)" "unprognostic (8.86e-2)" "unprognostic (1.05e-1)" "unprognostic (4.42e-2)" 0.1 0.4 2.3 1.6 1.5 0.1 0.3 5.8 1.4 0.8 0.0 8.2 1.4 1.3 2.5 0.9 0.9 0.9 0.8 0.6 1.6 0.9 0.7 0.0 0.1 0.7 3.1 3.6 0.0 0.0 0.1 5.0 1.0 1.3 2.4 0.3 0.2 4.5 10.1 1.3 2.0 2.1 0.2 0.4 1.6 0.4 6.1 0.1 0.1 4.3 0.0 0.7 0.8 2.9 0.0 0.0 0.1 0.1 1.8 1.0 0.0 5.5 3.4 1.1 1.6 0.0 0.1 0.1 0.0 7.4 0.1 0.2 0.0 0.1 2.2 0.0 0.2 0.0 0.4 0.5 0.2 0.1 0.1 1.8 0.1 41.4 0.0 1.4 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.1 0.4 0.1 0.0 0.1 9.0 0.0 0.0 0.2 0.5 0.0 0.3 0.2 2.7 12.6 0.1 0.0 0.0 5.5 0.0 1.4 6.2 4.0 0.0 0.0 12.6 0.0 46.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 1.5 5.8 1.4 0.6 1.6 0.7 3.1 1.0 0.2 6.1 2.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.0 0.6 0.6 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.1 3.3 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 1.5 0.6 0.0 0.0 0.4 0.0 0.2 0.0 0.7 0.1 0.0 0.0 11.5 1.8 0.9 3.4 0.0 0.3 0.1 0.0 2.6 0.0 0.5 GGCX VKCFD1 ENSG00000115486 "Gamma-glutamyl carboxylase" P38435 2 85544720-85561547 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 118.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018284 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA018284: AB_1849641" "unprognostic (4.88e-3)" "unprognostic (1.13e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (1.82e-6)" "unprognostic (5.67e-2)" "unprognostic (1.85e-3)" "unprognostic (2.96e-2)" "unprognostic (3.77e-2)" "unprognostic (5.64e-2)" "unprognostic (2.18e-2)" "unprognostic (6.45e-3)" "unprognostic (5.23e-2)" "unprognostic (8.17e-3)" "unprognostic (7.85e-2)" "unprognostic (2.59e-1)" "unprognostic (7.63e-3)" "unprognostic (9.38e-2)" 13.8 11.0 6.0 8.3 7.4 3.2 10.8 8.3 7.7 10.7 11.7 7.8 7.4 10.5 13.8 9.2 10.5 11.3 9.5 6.9 6.2 16.3 118.8 13.8 6.3 7.4 6.9 12.4 15.8 18.0 7.8 23.4 7.5 10.0 9.9 7.7 14.7 12.1 7.9 9.2 7.3 13.4 7.3 6.2 9.1 4.7 7.0 4.8 12.6 8.6 7.2 12.2 8.8 11.2 17.1 27.2 19.0 21.3 93.8 26.6 42.2 29.9 35.1 21.6 30.4 47.3 20.6 6.1 29.7 49.3 27.1 27.2 13.7 37.7 23.7 10.9 18.7 11.1 17.4 45.2 34.8 7.0 10.1 33.1 22.0 43.8 29.7 35.6 31.0 10.8 13.5 8.7 63.5 22.4 3.5 5.3 8.9 47.7 23.4 6.6 44.6 15.3 30.0 32.5 7.2 12.1 26.8 52.2 28.2 32.1 25.6 6.8 28.6 27.5 23.9 27.1 20.9 6.8 20.1 5.1 26.5 7.1 39.4 3.7 4.2 2.2 1.7 4.4 1.6 0.4 0.7 0.7 2.9 0.4 1.7 1.6 1.7 1.4 2.6 2.4 1.2 2.0 6.0 7.4 8.3 7.7 6.9 6.2 7.4 6.9 7.5 7.3 7.0 11.2 27.1 28.9 40.3 10.1 25.1 18.7 20.6 27.8 13.6 21.6 22.9 19.8 27.9 32.9 24.1 29.5 16.7 60.8 28.4 16.1 7.9 29.9 4.2 16.9 19.4 20.8 14.4 5.7 10.9 39.5 50.2 29.4 11.7 26.8 15.8 17.8 23.9 163.0 31.3 8.4 8.9 17.6 22.4 26.9 29.0 2.2 20.2 24.5 21.4 5.6 29.6 19.5 17.5 9.5 12.6 25.0 12.6 20.3 38.4 16.4 16.2 27.1 16.9 33.6 6.6 42.3 22.8 23.5 11.2 20.0 15.2 53.8 20.8 15.1 16.4 23.6 GJA1 "CX43, GJAL, ODD, ODDD, ODOD, SDTY3" ENSG00000152661 "Gap junction protein alpha 1" P17302 6 121435595-121449727 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Cataract, Disease variant, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 250.0;Astrocytes: 276.2;Basal keratinocytes: 234.9;Cardiomyocytes: 199.7;Endometrial stromal cells: 215.5;Granulosa cells: 494.3;Suprabasal keratinocytes: 378.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 462.7;HUVEC TERT2: 362.3;NTERA-2: 365.8;SuSa: 453.4;U-87 MG: 350.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB010753, HPA035097, HPA047551, HPA069245" Enhanced Supported Supported "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cell Junctions" Nucleoplasm "CAB010753: AB_476857, HPA035097: AB_2674460, HPA047551: AB_2732540, HPA069245: " "unprognostic (3.37e-2)" "unprognostic (3.41e-3)" "unprognostic (2.95e-1)" "unprognostic (4.18e-2)" "unprognostic (1.48e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (6.78e-2)" "unprognostic (2.89e-2)" "unprognostic (1.56e-1)" "unprognostic (5.47e-2)" "unprognostic (1.00e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.39e-1)" "unprognostic (1.29e-1)" "unprognostic (3.00e-3)" 121.2 287.6 313.5 24.7 310.2 0.9 60.6 260.1 409.0 261.7 193.1 17.5 18.2 98.7 10.6 74.9 32.7 99.9 168.9 273.6 362.6 21.2 10.6 67.9 21.1 340.3 380.9 43.5 19.4 236.2 31.3 290.2 307.4 83.3 19.7 3.3 35.6 148.0 10.3 388.2 24.7 112.5 335.9 4.2 30.7 36.9 373.3 24.3 169.1 22.1 34.9 116.0 184.9 341.0 0.1 43.5 186.8 0.4 99.7 61.5 0.4 142.5 286.9 46.9 113.7 0.7 0.4 0.0 15.8 55.8 40.2 18.3 5.1 87.4 151.3 0.1 51.6 2.3 15.7 0.0 124.1 0.0 0.4 164.6 92.1 172.5 61.7 462.7 362.3 0.0 0.1 4.3 9.4 8.4 0.1 80.6 365.8 0.1 47.2 0.1 0.0 3.7 188.6 21.0 0.4 2.9 0.0 0.3 0.1 453.4 14.9 0.3 269.5 143.8 39.4 122.8 93.5 0.1 0.1 0.1 350.4 0.1 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 313.5 310.2 260.1 409.0 273.6 362.6 340.3 380.9 307.4 335.9 373.3 341.0 152.2 250.0 80.0 276.2 0.1 234.9 133.6 71.1 77.4 0.3 9.5 20.1 199.7 0.0 17.5 1.8 2.1 53.4 0.4 0.0 0.0 76.9 0.5 21.5 215.5 166.6 0.0 0.0 0.3 4.2 7.9 124.4 0.5 51.7 8.8 494.3 33.9 0.1 8.6 0.0 0.6 0.0 4.1 0.9 55.3 1.7 2.5 3.6 44.4 15.0 0.6 0.3 0.0 4.0 1.0 10.8 0.0 4.1 0.1 29.7 0.0 0.1 6.2 0.3 0.0 5.9 80.2 0.9 1.8 68.3 378.2 20.0 4.9 127.1 0.4 52.7 GJB2 "CX26, DFNA3, DFNB1, NSRD1" ENSG00000165474 "Gap junction protein beta 2" P29033 13 20187463-20192938 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Ichthyosis, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 328.1;esophagus: 812.1;vagina: 519.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 69.8;Basal respiratory cells: 237.4;Basal squamous epithelial cells: 55.8;Ionocytes: 50.8;Squamous epithelial cells: 160.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 447.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 144.6;hTCEpi: 105.4;OE19: 76.9;RT4: 169.9" "Low region specificity" "Detected in all" "CAB013093, HPA014362" Uncertain Approved Mitochondria NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "CAB013093: AB_2533903, HPA014362: " "unprognostic (2.21e-1)" "unprognostic (1.25e-3)" "unprognostic (2.43e-2)" "unprognostic (6.14e-2)" "prognostic unfavorable (4.45e-4)" "unprognostic (9.77e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.33e-1)" "unprognostic (3.69e-3)" "prognostic unfavorable (2.90e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (2.53e-6)" "unprognostic (5.78e-3)" "unprognostic (2.40e-1)" "unprognostic (1.17e-2)" "unprognostic (8.93e-3)" 2.0 0.7 1.3 6.7 1.2 3.8 3.7 2.4 3.1 328.1 5.3 20.8 12.9 2.9 3.4 812.1 0.9 14.0 0.4 1.1 1.7 9.8 47.5 0.7 0.4 1.8 1.7 0.3 1.3 0.1 4.1 0.2 1.7 1.2 17.4 0.0 145.2 0.3 0.4 73.0 10.6 2.6 1.7 0.2 8.1 1.2 7.6 12.5 1.7 1.2 90.4 27.9 519.8 1.6 8.7 0.6 0.0 0.2 0.0 2.9 1.7 0.0 0.0 0.0 0.0 1.3 144.6 0.0 0.7 0.1 1.1 28.9 5.3 14.4 0.1 12.6 1.8 0.1 0.1 0.3 0.0 0.0 5.1 2.4 105.4 1.9 19.5 0.0 0.0 2.1 0.1 10.7 0.2 1.4 1.3 0.0 0.3 76.9 14.4 0.2 0.0 8.3 0.2 169.9 0.1 0.0 0.3 0.1 0.3 1.9 2.2 0.4 0.0 0.2 0.0 2.5 22.2 8.7 9.6 0.0 17.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 2.4 3.1 1.1 1.7 1.8 1.7 1.7 1.7 7.6 1.6 0.1 3.2 0.0 2.0 0.6 69.8 16.1 237.4 55.8 0.0 1.3 1.3 0.5 4.3 37.3 1.8 0.0 0.1 0.0 28.0 0.0 4.4 1.5 5.0 1.5 1.3 4.2 0.0 0.0 9.8 0.2 1.7 4.1 19.1 0.0 0.0 0.0 25.2 0.6 0.0 0.0 6.1 50.8 0.6 13.3 1.3 0.0 3.9 1.8 0.0 4.6 0.0 0.0 0.0 0.0 9.2 13.3 0.0 2.7 8.6 10.7 17.5 7.5 0.0 0.0 0.1 4.7 0.8 2.1 160.9 28.7 0.1 0.9 0.0 25.0 21.7 GJB3 "CX31, DFNA2, EKV" ENSG00000188910 "Gap junction protein beta 3" O75712 1 34781214-34786369 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 77.8;skin 1: 145.0" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 138.4;Basal prostatic cells: 71.9;Basal respiratory cells: 43.6;Pancreatic endocrine cells: 119.8;Prostatic glandular cells: 63.4;Squamous epithelial cells: 91.9;Suprabasal keratinocytes: 170.6;Urothelial cells: 171.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 58.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 88.8;CAPAN-2: 121.7;HaCaT: 99.4;HBEC3-KT: 84.9;hTCEpi: 136.8;OE19: 54.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA074472 Supported "Vesicles,Cell Junctions" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cell Junctions" "HPA074472: AB_2686694" "unprognostic (1.34e-3)" "unprognostic (2.30e-1)" "unprognostic (2.84e-2)" "unprognostic (5.22e-3)" "unprognostic (3.82e-2)" "unprognostic (2.00e-2)" "unprognostic (1.21e-4)" "prognostic unfavorable (4.56e-4)" "unprognostic (2.30e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.50e-2)" "unprognostic (5.74e-3)" "unprognostic (1.35e-1)" "unprognostic (1.22e-1)" "unprognostic (1.27e-2)" "unprognostic (2.46e-2)" 0.3 0.2 1.3 1.7 0.6 0.0 5.5 1.1 1.0 8.9 0.0 4.2 0.2 0.3 2.8 77.8 1.1 7.0 0.1 0.6 0.0 0.5 1.5 0.6 0.5 0.2 0.0 0.1 0.3 0.0 0.1 1.4 0.1 4.0 5.0 0.0 8.9 1.7 0.6 145.0 1.3 0.1 0.0 0.0 5.9 0.8 0.1 0.8 0.2 0.0 12.9 11.9 26.4 0.2 88.8 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 121.7 0.0 11.6 0.1 0.1 99.4 0.0 84.9 0.0 0.1 0.0 0.3 5.0 0.0 0.0 0.0 0.0 0.0 136.8 0.0 35.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.4 54.2 22.3 0.0 0.0 0.0 40.8 33.0 0.0 0.0 13.1 0.9 0.0 0.1 1.0 0.1 0.0 0.1 5.7 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 1.1 1.0 0.6 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.0 3.2 0.0 0.0 0.0 138.4 71.9 43.6 16.5 0.0 2.0 1.3 0.4 1.5 15.5 5.5 0.0 0.3 0.0 18.3 0.0 14.6 0.0 4.1 0.4 1.7 1.8 0.0 0.2 7.3 0.2 1.7 3.1 8.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 6.1 0.0 12.5 0.0 0.0 0.4 14.2 0.0 0.0 0.0 0.0 0.0 0.0 119.8 8.1 0.0 0.0 63.4 0.5 0.0 10.1 0.0 0.0 0.0 2.1 0.1 0.3 91.9 170.6 0.1 0.5 0.0 19.1 171.0 GJB4 CX30.3 ENSG00000189433 "Gap junction protein beta 4" Q9NTQ9 1 34759740-34762327 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 43.1" "Group enriched" "Detected in some" 4 "Basal prostatic cells: 31.1;Pancreatic endocrine cells: 37.0;Urothelial cells: 102.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 9.0;HaCaT: 12.2;HBEC3-KT: 8.3;hTCEpi: 5.7;OE19: 4.5;RPTEC TERT1: 4.8;RT4: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055112, HPA073904" Enhanced Supported "Cell Junctions" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA055112: AB_2682699, HPA073904: " "unprognostic (3.30e-2)" "prognostic favorable (5.48e-4)" "unprognostic (1.57e-1)" "unprognostic (2.70e-2)" "unprognostic (4.21e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-2)" "unprognostic (2.18e-2)" "unprognostic (5.40e-2)" "unprognostic (3.65e-1)" "prognostic unfavorable (3.24e-5)" "unprognostic (3.73e-2)" "unprognostic (5.81e-3)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (3.52e-4)" "unprognostic (5.42e-2)" 0.0 0.0 0.0 0.3 0.1 0.0 2.6 0.0 0.2 0.7 0.0 0.2 0.0 0.0 5.5 2.3 0.2 4.8 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.3 0.0 0.5 1.0 0.2 43.1 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.1 0.0 2.3 7.9 1.4 0.0 9.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 1.3 0.0 0.1 12.2 0.0 8.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 4.8 5.9 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 31.1 13.9 1.2 0.0 0.3 0.1 0.1 0.0 5.7 0.0 0.0 0.1 0.1 0.3 0.0 3.7 0.0 0.3 0.0 0.2 1.8 0.0 0.0 0.6 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 37.0 1.3 0.0 0.0 12.9 0.1 0.0 6.8 0.0 0.0 0.0 0.7 0.0 0.0 3.5 6.0 0.3 0.1 0.0 0.4 102.6 GJB6 "CX30, DFNA3, ED2, EDH, HED" ENSG00000121742 "Gap junction protein beta 6" O95452 13 20221962-20232365 "Disease related genes, Human disease related genes, Predicted membrane proteins" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 95.6;esophagus: 195.4;vagina: 139.3" "Cell type enhanced" "Detected in some" "Astrocytes: 58.8;Basal keratinocytes: 12.2;Basal respiratory cells: 15.6;Ionocytes: 12.2;Squamous epithelial cells: 31.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 145.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.6" "Lineage enriched" "Detected in single" 5 "T-cells: 2.6" "Cell line enriched" "Detected in some" 10 "RT4: 186.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014846 Supported "Cell Junctions" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA014846: AB_1847135" "unprognostic (5.57e-2)" "unprognostic (1.20e-1)" "unprognostic (3.90e-4)" "unprognostic (7.90e-2)" "unprognostic (2.37e-1)" "unprognostic (1.69e-1)" "unprognostic (1.83e-1)" "unprognostic (8.96e-2)" "unprognostic (9.64e-2)" "unprognostic (2.82e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-2)" "unprognostic (1.14e-11)" "unprognostic (8.99e-2)" "unprognostic (1.16e-1)" "unprognostic (6.35e-3)" "unprognostic (5.04e-2)" 0.5 0.2 55.8 0.3 59.4 95.6 3.8 73.0 80.9 65.9 36.0 0.0 0.0 0.9 0.2 195.4 0.4 1.3 0.1 50.2 63.5 0.0 0.1 0.3 0.8 60.0 71.8 0.0 0.1 0.0 4.4 0.0 57.5 0.2 0.1 0.0 34.5 0.0 0.1 56.8 0.2 0.0 47.7 0.2 0.3 1.4 76.3 37.6 5.3 0.0 15.4 10.3 139.3 42.7 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 4.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 186.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 1.1 0.6 0.5 0.0 0.0 0.0 2.6 0.2 55.8 59.4 73.0 80.9 50.2 63.5 60.0 71.8 57.5 47.7 76.3 42.7 0.0 0.0 0.0 58.8 0.0 12.2 1.7 15.6 4.0 0.0 0.0 0.1 0.6 0.0 4.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 6.9 5.8 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 12.2 0.0 0.4 4.6 0.0 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.1 0.3 31.0 3.8 0.0 0.3 0.0 0.0 2.4 GJC2 "CX46.6, CX47, GJA12, SPG44" ENSG00000198835 "Gap junction protein gamma 2" Q5T442 1 228149930-228159826 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 51.3" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 12.5;Oligodendrocytes: 26.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 5.4;SCLC-21H: 2.9;TIME: 2.7" "Region enhanced" "Detected in all" "white matter: 105.5" "Low region specificity" "Detected in all" HPA069619 Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA069619: " "unprognostic (2.67e-1)" "unprognostic (1.81e-2)" "unprognostic (6.42e-2)" "unprognostic (8.19e-3)" "unprognostic (4.24e-1)" "unprognostic (1.57e-1)" "unprognostic (6.94e-2)" "unprognostic (2.56e-1)" "unprognostic (4.99e-2)" "unprognostic (7.09e-2)" "unprognostic (7.88e-3)" "unprognostic (9.67e-2)" "unprognostic (6.09e-3)" "unprognostic (2.53e-2)" "unprognostic (7.36e-2)" "unprognostic (1.54e-1)" "unprognostic (2.02e-1)" 2.9 0.9 13.6 0.6 31.2 0.2 1.7 39.0 20.2 4.2 5.2 5.8 0.2 4.7 0.9 1.4 5.4 0.7 1.7 13.9 19.5 1.3 0.5 2.9 0.6 43.9 31.6 3.8 0.5 0.7 1.4 0.5 38.1 3.0 0.3 0.5 0.8 1.7 0.8 1.7 1.7 1.8 28.1 1.4 2.4 1.2 27.6 0.4 2.0 0.8 0.3 4.2 3.5 51.3 0.2 0.2 0.1 0.3 0.8 0.4 1.0 0.8 0.2 0.3 0.4 0.5 0.7 0.1 5.4 1.5 0.4 0.5 0.2 0.2 0.1 0.2 0.9 0.2 1.4 1.2 1.4 0.0 0.0 0.2 0.1 0.5 0.3 0.7 0.1 1.0 0.6 0.1 0.2 0.3 1.1 0.3 0.3 0.0 1.1 0.2 0.1 0.0 0.4 0.0 2.9 1.7 0.2 0.0 0.2 0.1 0.1 0.2 2.7 0.7 2.1 2.5 0.9 0.1 0.4 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.6 31.2 39.0 20.2 13.9 19.5 43.9 31.6 38.1 28.1 27.6 51.3 2.8 0.0 0.6 0.7 0.2 3.4 1.3 0.6 1.8 2.6 1.3 0.6 1.8 0.0 0.0 0.0 12.5 0.0 0.4 0.2 0.0 0.1 0.2 1.0 1.1 4.3 0.0 0.0 0.8 0.5 0.0 2.2 0.0 1.6 0.0 0.3 3.6 0.0 0.1 3.3 1.1 0.3 0.0 0.6 3.8 0.0 2.5 1.3 1.8 0.0 0.0 0.3 0.0 0.0 26.9 1.1 0.0 4.1 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.6 1.8 0.0 0.0 0.5 1.7 0.0 0.8 0.6 0.3 1.0 GLDN "CLOM, COLM, colmedin, CRG-L2, UNC-122" ENSG00000186417 Gliomedin Q6ZMI3 15 51341655-51408005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 84.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 510.8" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 2.7;MCF7: 1.3;SuSa: 1.8;U-266/70: 3.3;U-266/84: 2.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050873, HPA059441" Uncertain Supported "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 410000 "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA050873: , HPA059441: AB_2684018" "unprognostic (5.04e-2)" "unprognostic (2.57e-2)" "unprognostic (5.15e-5)" "unprognostic (3.21e-3)" "unprognostic (2.82e-2)" "unprognostic (2.33e-1)" "unprognostic (2.07e-4)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (3.30e-2)" "unprognostic (3.15e-1)" "unprognostic (2.14e-2)" "unprognostic (9.89e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (3.80e-3)" "unprognostic (1.37e-1)" 18.5 2.3 18.1 1.6 51.1 0.7 9.7 35.0 28.6 1.8 0.0 3.5 0.2 0.5 0.5 0.5 1.2 3.4 5.0 15.5 31.2 0.4 0.1 8.7 0.2 47.6 48.9 0.5 0.5 0.4 0.6 3.9 56.4 2.4 6.4 1.3 1.4 0.7 1.0 5.0 0.6 0.6 26.0 2.9 2.1 0.2 41.7 0.1 0.8 0.9 0.2 1.5 1.5 84.8 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 2.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.8 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 1.0 0.0 1.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 3.3 2.9 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 18.1 51.1 35.0 28.6 15.5 31.2 47.6 48.9 56.4 26.0 41.7 84.8 40.1 0.0 2.6 2.0 0.0 6.2 0.0 0.3 0.0 9.2 0.2 0.3 8.4 0.0 0.1 0.0 0.0 5.2 0.0 47.0 0.0 0.0 0.0 0.0 0.1 3.7 1.2 0.0 7.4 0.0 0.6 7.9 4.6 0.2 0.0 4.5 0.0 0.2 4.9 0.0 17.2 1.7 0.0 14.9 9.5 0.0 0.3 16.1 3.6 42.2 0.0 0.3 0.0 2.0 510.8 0.1 28.6 0.0 0.0 0.1 0.0 0.1 0.9 0.8 0.0 4.7 9.8 0.1 0.1 0.0 4.0 100.4 0.6 0.4 5.1 1.6 GLE1 "GLE1L, hGLE1, LCCS1" ENSG00000119392 "GLE1 RNA export mediator" Q53GS7 9 128504719-128542288 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 77.0;Late spermatids: 58.1;Spermatocytes: 51.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041689, HPA043538, HPA061560" Supported Supported "Nuclear membrane,Nucleoli" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear membrane" Nucleoli "HPA041689: AB_2677617, HPA043538: AB_2678539, HPA061560: AB_2684560" "unprognostic (8.74e-3)" "unprognostic (2.18e-2)" "unprognostic (1.17e-1)" "prognostic favorable (7.49e-4)" "unprognostic (1.75e-1)" "unprognostic (5.58e-2)" "unprognostic (7.91e-2)" "unprognostic (1.90e-1)" "unprognostic (1.91e-1)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (7.95e-2)" "unprognostic (4.00e-2)" "prognostic favorable (7.04e-4)" "unprognostic (2.62e-1)" "unprognostic (1.99e-3)" "unprognostic (5.64e-2)" 11.6 14.0 9.2 15.7 9.2 15.1 15.7 12.4 11.3 13.0 13.4 17.4 16.2 11.6 10.8 16.4 14.1 7.8 14.9 8.9 8.8 14.1 16.3 12.3 20.4 8.7 9.2 16.2 9.5 17.6 14.1 9.2 8.6 11.8 18.3 16.5 11.1 12.4 22.5 19.1 15.8 12.9 8.4 15.2 12.9 32.0 9.3 25.9 13.3 12.4 22.2 12.8 12.3 8.9 29.6 54.5 26.2 44.9 25.3 25.5 34.6 29.2 24.9 40.2 28.4 36.8 20.1 59.6 23.0 33.0 38.6 101.4 45.9 41.7 34.5 56.9 29.8 30.6 57.8 34.6 28.5 49.9 38.8 18.1 39.7 45.6 48.5 22.3 22.9 54.7 44.7 51.0 46.7 68.6 49.5 35.2 22.2 79.1 46.7 49.8 64.2 79.0 27.3 26.1 30.9 23.1 71.3 42.7 25.9 21.1 78.9 34.9 17.0 42.5 28.1 50.2 41.2 50.9 131.9 45.9 39.9 37.5 46.8 40.0 21.1 24.4 22.1 26.0 18.1 13.4 17.2 20.0 22.1 20.5 15.2 17.7 18.0 27.4 27.5 13.0 22.3 19.8 9.2 9.2 12.4 11.3 8.9 8.8 8.7 9.2 8.6 8.4 9.3 8.9 4.0 9.6 9.0 11.1 11.4 6.5 5.3 10.4 8.6 7.6 8.8 7.6 13.0 5.7 7.2 7.3 8.4 16.1 6.9 13.2 5.9 11.7 77.0 12.2 7.4 3.6 5.4 12.0 14.0 6.2 11.7 7.6 10.2 9.4 9.5 10.9 4.6 14.2 15.7 10.1 15.5 12.7 8.2 15.1 5.7 58.1 10.2 13.5 3.6 10.3 20.0 8.9 15.5 18.1 15.5 8.3 8.0 6.4 13.4 6.1 16.3 13.7 12.6 8.6 13.1 7.7 7.3 51.3 25.5 14.4 6.8 13.3 12.1 7.1 14.1 5.4 GLI1 GLI ENSG00000111087 "GLI family zinc finger 1" P08151 12 57459785-57472268 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 11.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 6.5;Leydig cells: 29.5;Peritubular cells: 42.9;Sertoli cells: 13.1;Theca cells: 7.8" "Cancer enhanced" "Detected in many" "testis cancer: 7.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "AN3-CA: 24.2;BJ hTERT+: 16.9;NTERA-2: 14.0;RH-30: 60.6;U-266/70: 16.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009460, HPA065172, HPA068903" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "CAB009460: AB_2111764, HPA065172: AB_2685427, HPA068903: AB_2732122" "unprognostic (4.97e-4)" "unprognostic (5.53e-2)" "unprognostic (1.26e-1)" "unprognostic (5.58e-3)" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (1.80e-2)" "unprognostic (9.00e-2)" "unprognostic (1.88e-1)" "unprognostic (1.43e-1)" "unprognostic (8.52e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-8)" "unprognostic (4.59e-3)" "unprognostic (2.98e-2)" "unprognostic (2.78e-2)" "unprognostic (1.04e-2)" 2.4 1.2 1.3 1.7 1.6 0.5 1.5 3.5 1.9 11.1 0.4 3.0 2.5 9.5 6.6 0.6 3.7 5.5 2.1 1.0 2.1 1.4 0.8 1.6 0.7 1.9 2.4 1.5 0.8 0.0 1.0 0.5 1.7 4.2 4.1 0.0 1.5 2.8 0.6 1.7 3.3 2.4 1.7 0.9 1.9 4.7 4.2 0.3 2.3 1.8 1.0 4.4 3.1 1.1 0.1 9.8 3.2 24.2 0.7 0.1 0.3 0.9 16.9 2.1 2.3 0.3 0.7 3.1 0.0 0.5 2.3 1.7 1.8 1.1 0.4 2.7 0.3 0.1 1.2 0.2 2.7 0.7 1.4 0.8 0.4 3.1 1.0 4.2 0.3 2.2 0.4 7.8 1.0 0.0 0.7 0.5 14.0 0.8 0.9 1.2 60.6 1.7 2.7 0.0 0.1 0.1 0.2 0.1 0.4 2.4 0.0 0.3 0.1 2.2 7.7 0.6 0.3 16.7 1.0 5.7 2.0 1.3 3.8 0.8 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.1 1.9 0.0 0.0 0.1 0.2 0.0 1.3 1.6 3.5 1.9 1.0 2.1 1.9 2.4 1.7 1.7 4.2 1.1 0.4 0.0 0.0 2.0 0.7 0.1 0.4 0.3 0.0 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.1 3.5 0.5 0.0 0.0 0.1 0.0 0.1 6.5 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.4 2.5 29.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.9 0.1 0.2 0.0 1.3 0.0 0.0 13.1 1.9 1.6 0.3 1.1 0.2 0.6 0.1 0.5 7.8 0.1 0.1 GLI2 "HPE9, THP1, THP2" ENSG00000074047 "GLI family zinc finger 2" P10070 2 120735623-120992653 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 10.9" "Cell type enhanced" "Detected in some" "Astrocytes: 39.5;Fibroblasts: 10.4;Leydig cells: 25.1;Peritubular cells: 30.9;Skeletal myocytes: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 20.1;hTEC/SVTERT24-B: 13.1;U-2 OS: 17.9;WM-115: 18.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB008558, HPA074275" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "CAB008558: AB_2111910, HPA074275: AB_2686677" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (9.83e-3)" "unprognostic (4.63e-2)" "unprognostic (2.04e-1)" "unprognostic (9.43e-2)" "unprognostic (1.65e-2)" "unprognostic (2.19e-3)" "unprognostic (2.58e-1)" "unprognostic (9.23e-3)" "unprognostic (1.81e-2)" "unprognostic (4.49e-10)" "unprognostic (1.13e-1)" "unprognostic (8.88e-2)" "unprognostic (2.32e-2)" "unprognostic (1.42e-3)" 1.6 1.0 1.9 0.9 2.2 0.0 1.4 1.4 1.3 4.3 0.6 3.4 0.4 4.7 1.2 0.8 2.8 2.1 2.3 1.1 1.9 1.4 0.4 2.0 0.3 2.1 2.1 10.9 0.3 0.1 1.8 0.8 1.8 2.9 0.6 0.0 1.4 1.1 0.9 2.7 1.6 1.9 1.6 0.8 1.6 2.4 1.8 1.3 1.0 0.4 0.3 3.1 2.4 0.9 0.0 10.3 20.1 5.5 3.2 4.0 0.0 5.8 1.8 2.4 2.4 0.0 0.5 0.0 0.9 5.2 0.9 0.3 4.3 0.2 1.9 0.0 2.1 0.4 6.1 0.2 3.8 0.0 1.2 2.3 0.0 13.1 0.0 2.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 10.6 1.6 4.3 0.1 2.2 3.5 0.0 0.0 2.0 2.1 3.8 0.0 0.2 4.3 0.1 0.0 5.1 0.0 17.9 2.5 0.0 0.0 0.1 0.0 7.4 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.2 1.4 1.3 1.1 1.9 2.1 2.1 1.8 1.6 1.8 0.9 0.3 0.0 0.0 39.5 0.0 2.0 0.1 0.5 0.6 0.0 0.1 0.9 1.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.1 0.3 6.1 0.5 0.0 0.0 0.7 0.2 0.1 10.4 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 1.5 2.1 25.1 0.1 0.0 2.8 0.0 0.0 1.0 3.0 0.3 1.0 0.0 30.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 16.0 3.4 0.1 3.6 0.1 1.7 0.0 0.0 7.9 0.0 0.1 GLI3 "ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV" ENSG00000106571 "GLI family zinc finger 3" P10071 7 41960949-42264100 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 8 "Astrocytes: 301.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 47.1;WM-115: 34.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005534 Approved Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Nucleoli, Vesicles" "HPA005534: AB_1078973" "unprognostic (2.53e-1)" "unprognostic (2.41e-2)" "unprognostic (7.58e-2)" "unprognostic (8.22e-3)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.35e-3)" "unprognostic (2.24e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-1)" "unprognostic (3.54e-2)" "unprognostic (1.48e-5)" "unprognostic (9.13e-3)" "unprognostic (5.41e-2)" "unprognostic (3.21e-3)" "unprognostic (7.00e-2)" 6.1 1.9 9.2 3.6 8.8 0.1 8.9 1.0 5.4 7.2 0.0 11.6 1.2 11.8 2.7 3.7 8.2 3.8 1.6 6.3 5.5 1.7 0.3 3.4 0.9 1.7 10.4 13.2 0.7 0.5 1.1 11.9 3.0 5.5 2.9 1.8 2.8 8.2 1.1 8.3 3.4 10.7 0.5 1.1 2.6 1.7 14.4 3.0 4.6 2.3 1.7 4.8 7.3 2.3 0.0 0.0 47.1 0.4 16.9 23.6 3.5 3.1 9.0 9.3 12.8 0.0 0.0 0.0 1.7 22.1 22.7 10.1 8.7 8.9 10.8 0.0 7.0 0.0 6.0 0.0 9.0 0.0 0.1 21.0 12.9 10.6 6.8 5.7 10.6 5.4 0.0 0.2 5.6 5.6 0.4 0.0 20.9 0.0 21.2 12.4 0.1 1.4 0.2 6.4 1.5 0.0 6.3 7.0 4.1 23.8 8.0 0.1 11.3 13.6 18.8 16.0 6.0 0.1 0.0 0.0 7.3 0.2 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 8.8 1.0 5.4 6.3 5.5 1.7 10.4 3.0 0.5 14.4 2.3 2.9 0.0 7.7 301.3 0.2 23.5 7.2 8.5 31.9 1.6 20.5 27.1 1.8 0.0 2.3 1.8 0.0 21.1 0.5 0.0 0.0 0.0 16.6 2.4 12.6 3.4 0.0 0.0 0.8 0.0 13.6 25.9 0.0 4.6 1.3 10.5 3.9 0.0 3.3 0.0 3.6 0.1 6.1 0.3 6.3 5.4 19.3 0.4 8.8 22.5 0.0 13.6 0.0 8.5 0.7 0.1 0.0 3.4 1.2 6.6 0.0 3.8 1.5 1.1 13.1 17.0 12.1 0.3 2.2 7.9 15.5 34.2 0.7 5.2 0.1 5.0 GLIS2 NPHP7 ENSG00000126603 "GLIS family zinc finger 2" Q9BZE0 16 4314761-4339597 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 22.1;Peritubular cells: 33.8;Proximal tubular cells: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 36.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062755, HPA065406" Enhanced Nucleoplasm NA NA "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA062755: , HPA065406: " "unprognostic (2.86e-1)" "unprognostic (3.27e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.59e-5)" "unprognostic (3.76e-1)" "unprognostic (5.15e-2)" "unprognostic (8.13e-2)" "unprognostic (6.65e-2)" "unprognostic (3.94e-1)" "unprognostic (2.37e-3)" "unprognostic (3.59e-1)" "unprognostic (2.48e-1)" "prognostic favorable (8.06e-6)" "unprognostic (1.59e-3)" "unprognostic (3.18e-2)" "unprognostic (1.24e-2)" "unprognostic (4.40e-3)" 16.3 23.4 4.4 2.5 4.1 0.1 11.4 5.2 3.9 22.3 3.3 19.2 1.5 20.9 0.7 4.9 17.3 5.6 30.9 3.1 3.8 41.5 3.2 30.6 1.6 5.6 5.6 27.5 13.2 2.3 18.9 4.4 4.3 21.7 0.4 0.7 9.8 4.0 3.0 7.1 7.4 3.3 4.4 4.5 11.9 5.3 5.5 0.2 19.4 0.4 0.5 20.2 11.4 2.5 6.1 12.3 2.0 4.8 1.5 7.2 4.3 6.1 5.3 2.3 1.6 3.2 5.1 0.0 10.8 6.0 2.2 3.7 1.2 5.6 0.1 8.9 0.3 0.0 10.9 1.9 6.9 0.0 0.9 4.1 1.2 1.9 0.9 2.6 1.9 0.1 0.5 2.0 1.3 4.0 0.0 1.2 4.6 0.7 2.2 11.7 2.6 6.7 0.4 0.0 0.9 4.6 6.1 2.9 1.7 0.6 8.2 1.0 3.2 3.2 6.0 36.8 1.9 1.4 0.9 1.5 1.4 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 4.1 5.2 3.9 3.1 3.8 5.6 5.6 4.3 4.4 5.5 2.5 4.8 16.0 9.8 8.5 0.0 5.6 5.4 8.7 1.8 10.6 3.5 2.4 5.9 15.7 5.6 12.9 4.2 0.9 0.1 0.0 19.6 11.8 0.2 1.8 9.0 6.9 0.0 0.0 2.1 8.3 0.9 18.3 0.5 2.1 0.0 2.6 6.8 0.7 0.4 6.7 3.2 0.2 2.0 0.3 6.1 0.9 22.1 0.8 3.6 5.6 1.0 10.4 0.0 4.0 1.3 10.3 0.0 33.8 0.0 5.1 0.0 21.7 3.1 7.3 0.0 8.2 14.6 0.2 3.4 0.7 2.8 1.1 0.7 0.1 0.0 2.8 GLMN "FAP48, FKBPAP, GLML, GVM, VMGLOM" ENSG00000174842 "Glomulin, FKBP associated protein" Q92990 1 92246402-92298987 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 39.1" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 102.2;Excitatory neurons: 97.8;Inhibitory neurons: 91.5;Oligodendrocyte precursor cells: 72.9;Rod photoreceptor cells: 148.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031446, HPA031448" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "HPA031446: AB_2797222, HPA031448: AB_2673888" "unprognostic (4.20e-2)" "unprognostic (3.47e-2)" "prognostic favorable (1.71e-4)" "unprognostic (7.37e-2)" "unprognostic (1.38e-1)" "unprognostic (7.24e-2)" "prognostic unfavorable (2.42e-5)" "unprognostic (7.32e-2)" "unprognostic (2.07e-3)" "unprognostic (4.59e-2)" "unprognostic (9.88e-2)" "unprognostic (1.81e-2)" "prognostic unfavorable (5.89e-8)" "unprognostic (7.33e-2)" "unprognostic (5.21e-2)" "unprognostic (1.89e-1)" "unprognostic (3.58e-1)" 3.4 4.6 3.6 6.1 4.7 7.5 7.0 6.8 5.8 4.8 4.1 4.7 3.6 6.0 5.7 6.5 3.8 4.0 5.3 4.6 3.3 4.5 3.9 3.8 8.3 2.5 2.9 5.0 3.0 5.3 3.7 5.6 2.7 5.1 4.9 39.1 2.7 3.8 5.2 9.4 4.5 4.7 2.9 4.4 3.8 8.2 2.8 8.6 6.2 4.4 8.8 5.4 4.2 4.1 21.5 8.8 26.7 14.6 9.1 14.2 25.0 15.0 12.5 18.6 16.2 16.2 8.3 22.1 23.4 8.9 27.1 16.2 14.3 13.5 25.4 16.8 20.7 29.1 16.5 16.5 9.0 38.7 14.7 11.2 7.5 21.1 9.3 7.3 19.7 19.6 24.9 12.9 23.7 4.8 23.7 27.8 40.2 10.9 17.4 19.1 36.7 14.9 20.6 20.9 24.3 12.7 25.3 24.1 15.6 15.4 11.5 34.9 13.9 12.8 12.5 22.3 22.4 11.7 18.1 28.6 4.8 36.8 7.7 0.0 0.6 1.2 3.0 1.4 5.5 2.6 3.0 3.6 2.1 1.8 2.8 3.2 0.1 7.4 0.7 1.6 2.6 1.5 3.6 4.7 6.8 5.8 4.6 3.3 2.5 2.9 2.7 2.9 2.8 4.1 6.8 9.6 8.3 29.7 16.7 8.9 13.7 16.2 12.0 28.3 7.6 6.7 10.0 7.2 8.5 12.9 102.2 15.1 31.6 2.9 1.9 5.9 1.7 4.9 13.6 7.9 10.7 12.8 97.8 5.2 12.1 10.5 9.2 5.4 8.2 10.7 5.7 2.1 8.3 26.9 91.5 4.4 10.2 3.9 7.7 1.1 12.5 7.1 8.8 28.1 6.8 14.2 37.0 72.9 46.0 5.3 3.3 7.9 12.2 9.6 2.3 9.7 4.0 148.1 6.6 10.5 18.9 19.8 30.1 9.4 8.9 15.7 28.3 15.0 5.5 7.7 GMNN Gem ENSG00000112312 "Geminin DNA replication inhibitor" O75496 6 24774931-24786099 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "DNA replication inhibitor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 231.4" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 184.8;Paneth cells: 300.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011458, CAB047327, CAB047328, HPA049977, HPA054597" Enhanced Supported Nucleoplasm,Cytosol Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 25: Pancreas - Digestion" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "CAB011458: AB_2110946, CAB047327: , CAB047328: , HPA049977: AB_2680978, HPA054597: AB_2682538" "unprognostic (1.37e-1)" "unprognostic (3.43e-3)" "unprognostic (3.91e-3)" "unprognostic (1.52e-2)" "unprognostic (1.28e-1)" "unprognostic (4.37e-2)" "unprognostic (2.90e-3)" "unprognostic (8.29e-2)" "unprognostic (1.23e-3)" "prognostic favorable (4.13e-4)" "prognostic unfavorable (9.77e-4)" "unprognostic (1.33e-2)" "prognostic unfavorable (7.82e-5)" "unprognostic (2.25e-1)" "unprognostic (7.92e-2)" "unprognostic (3.63e-2)" "unprognostic (5.90e-3)" 10.1 7.7 16.9 17.2 18.2 68.9 24.2 19.5 23.7 11.1 13.5 41.6 17.8 10.6 5.8 16.6 16.5 7.9 8.0 14.7 20.2 24.6 18.2 8.9 30.4 17.0 20.2 14.6 231.4 8.4 11.1 16.5 17.8 41.5 44.4 16.3 8.7 24.9 7.4 40.3 16.1 12.5 16.4 19.1 22.6 37.4 19.8 37.4 10.8 14.3 23.7 28.4 13.9 15.5 110.9 64.2 159.2 66.2 22.2 23.5 106.0 106.0 55.9 124.4 135.5 125.1 38.8 110.1 131.3 34.4 91.3 63.3 139.4 78.1 133.0 41.2 145.4 151.5 109.3 207.4 20.7 119.1 53.1 19.1 25.1 75.9 29.5 25.8 62.2 84.6 193.9 56.9 88.9 86.3 224.9 128.2 87.3 89.6 50.2 128.9 124.4 141.2 53.5 94.6 127.3 78.3 47.5 77.4 95.2 89.1 81.3 72.0 30.9 75.7 76.8 88.3 182.6 62.8 207.6 210.3 23.1 220.9 111.2 5.5 5.2 17.1 4.4 6.9 5.6 9.2 8.5 6.9 7.6 4.6 6.1 6.9 3.0 5.9 5.0 9.4 15.9 5.6 16.9 18.2 19.5 23.7 14.7 20.2 17.0 20.2 17.8 16.4 19.8 15.5 24.0 6.4 15.6 8.8 17.0 33.0 28.4 57.4 18.8 9.5 51.0 52.5 12.1 18.6 68.1 44.1 2.1 83.2 19.9 72.6 9.8 113.6 94.8 84.8 30.6 18.4 25.9 66.2 3.5 112.3 136.3 17.7 12.2 184.8 13.3 36.4 13.9 17.4 54.0 11.8 5.3 66.3 10.2 10.7 13.2 28.0 9.6 15.2 23.2 5.6 12.6 30.9 6.2 5.5 3.2 31.8 300.5 10.9 41.6 25.6 20.8 20.6 25.2 13.7 19.7 8.0 21.9 158.8 58.8 26.8 63.5 48.7 19.1 30.4 156.5 30.1 GNAI3 87U6 ENSG00000065135 "G protein subunit alpha i3" P08754 1 109548615-109600195 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 350.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022099, HPA042141" Approved Approved Nucleoplasm,Nucleoli,Centrosome NA NA 1400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 41: Macrophages - Immune response" Centrosome "Nucleoplasm, Nucleoli" "CAB022099: , HPA042141: AB_2677870" "unprognostic (2.19e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.44e-2)" "unprognostic (2.59e-1)" "unprognostic (9.45e-3)" "prognostic unfavorable (5.30e-6)" "unprognostic (2.56e-3)" "unprognostic (2.18e-2)" "prognostic favorable (4.59e-4)" "unprognostic (1.83e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.34e-4)" "unprognostic (7.27e-2)" "unprognostic (1.39e-1)" "unprognostic (1.25e-2)" "unprognostic (1.66e-2)" 12.7 8.2 5.8 14.2 6.1 27.7 11.9 7.3 7.5 10.9 8.6 11.8 10.4 12.1 8.0 21.8 8.0 11.3 4.2 6.0 6.5 11.2 15.3 9.7 14.1 6.7 5.9 8.8 9.3 8.9 1.8 14.8 6.8 10.3 11.8 17.8 7.7 9.0 3.8 18.4 10.6 13.6 6.3 11.4 9.0 8.7 6.2 14.2 8.0 5.5 15.9 15.5 4.0 7.3 48.3 16.4 31.0 17.3 28.4 35.0 25.7 35.3 28.6 36.0 35.5 24.4 16.1 25.3 22.4 37.6 21.6 24.5 30.0 35.3 49.4 29.2 18.0 22.1 26.3 21.9 25.1 34.9 18.8 25.2 30.4 41.3 27.8 24.2 42.8 19.1 29.8 24.2 35.5 32.9 27.3 28.4 31.3 23.0 19.1 19.2 73.6 16.6 37.4 35.4 19.5 34.9 24.7 27.6 39.4 22.8 21.1 30.5 36.7 29.4 40.7 44.9 39.2 25.6 30.2 29.2 47.6 34.4 47.1 32.4 29.7 57.8 21.1 44.3 22.4 20.1 20.4 20.6 31.9 17.1 16.8 19.4 53.8 19.9 44.6 14.2 23.8 36.3 5.8 6.1 7.3 7.5 6.0 6.5 6.7 5.9 6.8 6.3 6.2 7.3 104.0 44.8 31.5 17.0 76.6 151.2 104.3 92.2 63.2 29.9 67.7 45.3 14.3 37.1 61.0 58.8 350.3 80.3 98.8 63.9 64.6 97.9 14.7 65.5 71.5 82.6 84.3 43.8 37.5 101.7 153.7 69.2 55.5 110.9 46.3 50.1 56.7 57.2 107.9 25.2 36.4 72.3 59.0 115.0 106.9 9.4 48.7 127.4 74.7 31.9 102.4 47.9 45.3 35.7 31.3 101.6 58.9 47.4 66.3 72.5 48.9 53.5 51.7 26.2 52.6 59.0 77.6 68.6 54.7 82.1 188.4 106.9 94.3 51.7 63.5 143.0 GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, P84996, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transducer "Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 1886.1;Late spermatids: 1756.9;Skeletal myocytes: 1998.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (3.90e-2)" "unprognostic (4.77e-2)" "unprognostic (8.37e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-3)" "unprognostic (8.01e-2)" "unprognostic (4.29e-2)" "prognostic favorable (8.76e-4)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (5.24e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-2)" "unprognostic (1.36e-1)" 784.8 1215.3 1564.4 512.6 1524.7 887.4 578.9 1413.1 1768.3 828.5 1373.3 657.1 492.4 611.4 1253.8 883.1 742.9 672.7 1990.6 1557.3 2716.9 625.0 651.1 640.3 769.2 1710.5 1949.4 766.5 1917.7 1799.4 1153.6 884.6 1963.4 577.3 607.3 731.2 2943.9 594.4 2400.4 526.8 527.3 782.4 1598.4 606.6 587.1 357.9 1882.0 854.4 3432.2 2813.1 800.0 687.1 239.3 1483.9 215.6 897.3 1501.9 663.3 2691.8 1822.3 1200.1 1219.1 1635.0 1937.3 1201.8 2480.5 1446.7 911.9 1670.3 2314.3 1305.6 976.1 1499.0 2195.3 1540.9 401.4 784.6 984.9 1651.7 2232.7 1420.7 641.6 483.0 1566.4 1113.6 875.1 1399.1 1561.0 1669.7 1100.6 692.0 1294.6 1319.1 4131.0 1759.5 1452.8 487.9 214.0 894.4 1436.7 1287.3 1589.4 2165.5 1315.8 1818.3 3853.2 2157.6 2117.1 1354.2 1921.8 1570.0 1581.7 1343.3 2210.2 1477.0 688.5 1452.3 1314.0 993.3 1583.2 900.0 473.7 1107.1 217.9 96.7 114.2 68.9 127.3 80.0 103.2 73.4 74.8 129.2 93.6 65.8 82.6 103.4 95.6 150.3 174.9 92.7 100.9 1564.4 1524.7 1413.1 1768.3 1557.3 2716.9 1710.5 1949.4 1963.4 1598.4 1882.0 1483.9 982.6 221.2 258.8 192.0 310.8 130.4 182.0 130.0 205.5 397.8 465.6 684.4 1025.3 237.4 212.2 261.1 56.3 832.6 390.8 357.3 444.1 233.9 734.9 487.7 515.7 518.3 463.1 252.1 232.5 228.9 342.0 380.9 196.3 685.0 138.6 542.3 380.1 256.4 379.1 1886.1 439.7 327.2 181.0 380.4 405.7 1756.9 265.3 437.1 222.3 236.1 204.0 1367.2 137.0 194.5 166.6 339.9 300.0 197.1 309.7 268.1 273.7 153.6 218.0 222.0 210.4 1998.0 560.4 226.0 73.6 240.5 117.8 1211.7 301.8 860.9 304.4 316.5 GNPAT "DAP-AT, DAPAT, DHAPAT" ENSG00000116906 "Glyceronephosphate O-acyltransferase" O15228 1 231241207-231277973 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cataract, Disease variant, Dwarfism, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (8.87e-2)" "unprognostic (3.28e-2)" "unprognostic (3.36e-2)" "unprognostic (2.56e-2)" "unprognostic (5.25e-3)" "unprognostic (1.91e-1)" "unprognostic (5.07e-2)" "unprognostic (6.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (8.29e-6)" "unprognostic (5.69e-2)" "unprognostic (1.66e-1)" "unprognostic (4.48e-2)" "unprognostic (2.68e-1)" 22.4 26.9 21.6 20.5 24.0 17.3 21.7 23.9 28.2 18.3 25.2 30.0 30.0 20.3 23.7 22.1 27.9 18.2 44.9 22.0 23.5 25.7 30.9 18.7 23.6 24.1 22.5 22.5 29.5 22.6 17.9 19.4 23.3 22.8 24.8 17.0 26.4 20.9 101.9 23.6 28.1 26.4 23.6 18.5 26.9 32.0 23.2 27.5 20.8 84.1 25.8 21.5 17.0 26.1 39.8 43.6 60.4 46.1 48.7 71.4 40.7 32.9 37.1 34.1 39.1 56.1 48.3 57.0 40.4 49.5 35.9 41.9 40.6 44.7 50.0 64.8 37.2 41.2 41.4 81.7 49.4 70.9 31.4 50.1 53.8 35.5 39.6 44.5 81.2 56.0 61.1 53.3 71.7 13.1 63.6 41.0 97.1 112.0 49.5 68.7 81.0 66.9 42.7 29.2 40.0 57.1 55.2 30.7 49.1 23.8 53.7 110.7 42.8 34.5 32.1 50.5 83.3 68.2 93.6 65.1 49.8 58.8 65.3 34.1 36.4 37.3 23.7 37.1 27.2 35.1 30.6 31.3 36.4 37.7 26.4 24.4 14.3 26.9 50.3 17.2 37.9 29.8 21.6 24.0 23.9 28.2 22.0 23.5 24.1 22.5 23.3 23.6 23.2 26.1 17.7 25.6 20.8 19.9 32.3 13.5 19.5 23.1 16.5 23.3 14.9 12.6 55.8 30.0 21.2 27.6 39.6 25.3 20.1 16.4 17.6 41.5 70.3 21.5 19.4 21.4 28.2 13.2 18.9 43.4 19.2 19.5 21.4 14.1 11.4 30.1 19.2 26.9 27.4 11.8 18.6 21.0 22.4 24.8 18.3 119.2 25.4 21.8 12.4 15.9 38.7 22.7 26.8 17.1 29.2 40.2 30.3 26.7 30.1 24.9 41.7 28.0 30.8 24.2 19.7 16.5 22.4 50.9 31.5 18.8 13.9 12.4 24.5 19.7 30.1 19.0 GORAB "FLJ11752, GO, NTKL-BP1, SCYL1BP1" ENSG00000120370 "Golgin, RAB6 interacting" Q5T7V8 1 170532131-170553834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027250, HPA027746" Approved Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "Nucleoplasm, Nucleoli, Cytosol" "HPA027250: AB_10611253, HPA027746: " "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (4.75e-3)" "prognostic favorable (1.39e-4)" "prognostic unfavorable (5.26e-4)" "unprognostic (8.48e-3)" "unprognostic (2.94e-2)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.77e-2)" "prognostic unfavorable (7.83e-12)" "unprognostic (2.52e-2)" "unprognostic (2.83e-1)" "unprognostic (7.71e-2)" "unprognostic (1.70e-1)" 3.1 5.2 1.6 1.9 1.6 0.6 2.8 1.6 3.1 3.8 1.9 3.6 1.4 3.2 3.5 2.3 2.1 2.1 3.1 1.5 2.3 2.5 4.3 2.5 3.6 1.6 1.8 4.3 3.7 1.9 3.0 3.1 1.7 2.8 3.3 1.3 3.3 2.6 1.1 1.9 2.7 2.0 1.7 3.1 2.1 2.0 2.0 2.8 3.0 2.1 3.0 3.1 3.3 1.8 3.4 3.8 4.5 2.0 9.0 5.8 2.9 4.8 7.5 3.6 4.6 1.9 4.9 5.1 6.1 4.3 2.4 4.0 6.4 2.8 6.0 4.8 1.6 2.5 4.0 2.8 4.9 4.4 3.1 4.4 2.5 4.2 3.9 5.5 3.5 2.3 4.4 2.3 5.3 0.6 5.8 4.0 4.7 6.2 4.0 3.9 3.8 6.0 4.2 1.9 1.4 3.0 3.6 4.8 11.5 3.1 2.7 8.4 4.4 6.8 3.1 2.9 7.2 3.5 4.4 3.8 5.2 4.0 5.4 0.7 3.9 0.0 2.3 4.2 3.9 2.8 4.1 3.5 4.3 2.8 3.6 3.0 0.5 3.8 3.1 2.7 5.3 2.6 1.6 1.6 1.6 3.1 1.5 2.3 1.6 1.8 1.7 1.7 2.0 1.8 8.1 0.0 11.4 8.8 8.9 2.8 4.0 6.5 8.6 4.7 5.2 7.1 9.4 10.0 7.1 5.5 2.1 6.0 6.2 12.8 3.9 12.3 2.3 5.5 10.4 8.3 0.0 3.4 9.3 6.0 7.3 10.5 9.2 6.7 13.9 5.2 5.3 6.6 7.1 5.0 7.7 9.4 8.2 6.9 4.6 3.2 14.0 5.6 3.6 3.7 10.1 4.3 3.1 9.0 7.3 5.7 9.8 6.4 10.3 4.9 4.3 6.0 2.4 7.1 6.6 8.2 9.3 13.1 8.1 5.4 1.6 5.6 6.3 5.1 6.4 3.0 GPC3 "DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1" ENSG00000147257 "Glypican 3" P51654 X 133535745-133985594 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 574.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.1;Extravillous trophoblasts: 61.0;Fibroblasts: 404.2;Muller glia cells: 88.9;Syncytiotrophoblasts: 148.6" "Cancer enriched" "Detected in all" 4 "liver cancer: 269.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.8" "Group enriched" "Detected in some" 5 "HAP1: 514.3;Hep G2: 1825.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006316 Supported "Plasma membrane" NA NA 27000 "Cluster 32: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA006316: AB_1078994" "unprognostic (2.06e-1)" "unprognostic (2.36e-1)" "unprognostic (9.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (1.46e-1)" "unprognostic (6.10e-2)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (3.92e-3)" "unprognostic (6.06e-2)" "unprognostic (1.71e-1)" "unprognostic (3.81e-3)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" 99.9 22.8 0.5 3.5 1.0 0.0 61.8 0.5 0.3 11.8 0.2 6.5 1.6 9.2 41.1 6.7 13.9 13.7 24.5 0.3 4.0 87.0 5.1 122.9 2.5 1.9 3.1 15.5 21.2 4.1 47.0 574.9 3.0 8.3 4.1 6.2 13.7 9.2 4.5 18.0 5.6 7.3 1.7 3.7 13.6 2.8 2.0 8.0 22.4 28.6 10.9 14.6 9.3 1.0 0.0 0.0 21.8 1.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 154.0 0.0 0.0 0.1 0.1 0.0 0.0 514.3 0.4 0.0 0.0 22.6 0.0 0.9 1825.2 0.3 0.0 0.5 12.9 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.5 0.1 132.1 0.1 0.0 0.0 0.0 0.1 122.4 6.1 15.3 40.3 0.0 0.0 0.4 233.8 0.5 23.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.8 1.2 0.0 0.7 0.0 0.0 0.0 0.1 0.5 1.0 0.5 0.3 0.3 4.0 1.9 3.1 3.0 1.7 2.0 1.0 28.5 0.0 1.7 0.3 1.0 10.5 4.8 17.0 0.0 0.4 5.0 10.4 0.5 1.5 20.0 5.5 0.0 65.1 0.8 0.5 19.6 0.3 0.9 0.2 0.4 1.8 1.8 0.0 2.5 1.6 61.0 404.2 0.5 1.5 0.0 1.0 2.2 0.0 26.7 0.0 2.5 3.1 2.0 0.0 6.1 2.4 10.5 1.0 3.6 23.4 0.0 88.9 0.0 3.5 1.4 1.7 2.6 3.0 0.4 2.7 1.2 40.7 24.3 3.1 0.0 21.7 21.3 6.9 7.1 0.2 4.0 148.6 1.1 7.6 4.1 0.6 GPC4 K-glypican ENSG00000076716 "Glypican 4" O75487 X 133300103-133415489 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Alveolar cells type 2: 29.2;Astrocytes: 54.5;Extravillous trophoblasts: 36.2;Granulosa cells: 30.6;Proximal tubular cells: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 209.7;HAP1: 121.8;NTERA-2: 110.3;RPTEC TERT1: 276.6;SuSa: 242.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030834, HPA030836" Approved Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 190000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" Nucleoplasm "HPA030834: , HPA030836: AB_10601327" "unprognostic (9.60e-2)" "unprognostic (8.67e-2)" "unprognostic (2.29e-1)" "unprognostic (8.21e-2)" "unprognostic (8.51e-3)" "unprognostic (5.90e-3)" "unprognostic (5.68e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.54e-2)" "unprognostic (1.26e-1)" "unprognostic (5.87e-3)" "unprognostic (1.30e-1)" "prognostic favorable (1.25e-5)" "unprognostic (1.97e-1)" "unprognostic (2.89e-1)" "unprognostic (2.75e-1)" "unprognostic (2.72e-1)" 9.6 9.8 5.9 4.9 6.4 0.1 5.6 5.0 5.8 12.0 4.6 22.5 10.6 10.8 16.4 7.4 11.2 9.0 7.9 6.3 7.5 20.6 1.8 17.4 2.5 7.2 6.9 12.3 10.8 5.6 16.6 29.0 6.0 8.0 10.9 1.2 13.0 11.4 24.3 3.8 10.8 17.7 6.6 5.7 16.9 7.8 4.9 8.4 5.9 20.0 2.0 10.3 5.2 8.5 0.0 0.0 209.7 8.3 8.9 1.3 26.0 1.6 0.0 0.0 0.0 0.1 0.5 0.3 71.7 1.2 0.0 0.1 121.8 0.1 0.0 0.0 11.5 0.0 0.0 0.0 0.2 0.0 0.0 37.3 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.2 6.0 0.1 0.1 110.3 0.0 3.2 0.6 19.2 0.0 276.6 8.4 0.1 1.5 0.8 0.1 0.1 242.0 3.2 3.2 0.0 21.3 24.8 0.0 13.6 0.0 0.0 0.1 0.0 0.0 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.4 5.0 5.8 6.3 7.5 7.2 6.9 6.0 6.6 4.9 8.5 1.7 51.3 29.2 54.5 0.2 1.5 3.7 14.7 14.2 0.0 2.9 2.0 4.4 5.7 8.7 23.9 0.0 0.5 0.2 2.5 3.9 7.0 0.6 5.9 1.7 1.2 2.4 0.0 4.7 12.7 36.2 14.4 6.6 10.0 0.0 30.6 0.0 0.0 2.5 0.0 1.4 11.1 4.1 0.6 3.9 2.1 2.1 2.0 1.8 14.0 1.1 1.0 0.0 4.5 4.3 16.5 4.3 0.4 0.1 1.4 4.6 30.3 12.8 0.1 0.0 6.3 13.6 2.4 23.6 2.3 0.4 3.1 1.0 1.4 11.3 0.6 GPC6 ENSG00000183098 "Glypican 6" Q9Y625 13 93226807-94408020 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 163.2;Excitatory neurons: 333.6;Inhibitory neurons: 496.1;Oligodendrocyte precursor cells: 691.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 62.5;HSkMC: 70.8;hTERT-RPE1: 64.3;SuSa: 39.5;U-87 MG: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA017671 Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 420000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA017671: AB_1849833" "unprognostic (5.24e-2)" "unprognostic (4.65e-2)" "unprognostic (2.28e-1)" "unprognostic (9.76e-2)" "unprognostic (1.72e-1)" "unprognostic (5.50e-2)" "unprognostic (1.28e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "unprognostic (2.66e-2)" "unprognostic (2.33e-2)" "unprognostic (3.71e-2)" "unprognostic (2.53e-3)" "unprognostic (6.21e-3)" "unprognostic (7.42e-2)" "unprognostic (3.36e-1)" "unprognostic (3.35e-3)" 9.1 2.2 0.8 8.9 1.9 0.1 2.2 1.7 1.5 3.6 1.1 6.3 2.3 2.4 2.4 5.2 4.1 17.0 6.2 1.3 3.1 7.7 17.7 3.5 0.4 1.7 2.4 7.3 1.6 1.8 2.9 1.3 2.3 6.2 6.5 5.6 3.1 15.1 0.6 1.1 4.3 7.8 2.0 2.2 5.4 2.0 1.9 1.7 1.7 1.9 0.9 11.6 2.4 2.1 0.0 4.7 10.2 4.5 62.5 19.5 0.0 7.2 0.0 4.9 6.4 0.0 0.0 0.2 0.0 16.0 0.0 0.0 5.7 1.2 9.1 0.0 4.1 0.0 0.1 20.2 37.8 0.1 0.1 70.8 0.5 11.7 8.1 64.3 0.0 0.0 0.0 0.1 6.9 0.0 0.0 0.1 6.4 0.0 3.4 0.0 1.6 0.1 5.5 0.0 4.1 16.8 0.0 1.9 0.0 39.5 14.0 0.0 0.0 26.9 22.6 25.4 12.3 15.9 0.1 0.0 52.8 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 1.9 1.7 1.5 1.3 3.1 1.7 2.4 2.3 2.0 1.9 2.1 0.6 0.0 0.5 163.2 0.0 0.6 0.5 0.5 0.6 50.3 0.6 1.9 1.7 4.3 0.7 7.3 10.4 0.2 0.0 0.1 0.0 0.3 6.7 1.6 25.9 1.1 0.0 0.0 333.6 0.0 0.1 31.2 0.0 3.1 0.0 36.0 5.7 41.2 0.5 0.0 496.1 0.1 2.0 1.3 1.0 5.0 4.7 0.5 1.8 31.9 0.0 2.7 0.0 691.6 13.2 0.1 0.0 1.9 0.1 1.6 0.0 14.5 0.0 115.0 0.0 34.4 20.9 4.2 2.7 0.5 0.4 0.1 0.7 11.9 0.1 0.2 GPX4 "MCSP, PHGPx" ENSG00000167468 "Glutathione peroxidase 4" P36969 19 1103926-1106791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Oxidoreductase, Peroxidase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 18580.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008630, HPA047224, HPA058546" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "CAB008630: AB_1616685, HPA047224: AB_2679990, HPA058546: AB_2683749" "unprognostic (8.42e-3)" "prognostic favorable (7.18e-4)" "unprognostic (8.14e-3)" "prognostic favorable (1.84e-5)" "unprognostic (1.00e-1)" "unprognostic (8.72e-2)" "unprognostic (2.53e-3)" "unprognostic (8.49e-2)" "unprognostic (2.69e-2)" "unprognostic (1.47e-1)" "prognostic favorable (7.72e-4)" "unprognostic (1.29e-1)" "prognostic favorable (8.61e-4)" "unprognostic (1.61e-2)" "unprognostic (2.20e-1)" "unprognostic (6.67e-3)" "unprognostic (2.96e-2)" 927.8 535.3 415.1 127.4 428.7 178.0 733.3 440.7 519.1 280.8 478.7 249.0 259.0 188.4 318.9 220.4 199.2 196.6 426.0 419.2 450.3 536.5 687.8 307.9 216.4 430.9 448.3 260.3 157.9 285.5 398.4 147.2 454.1 322.1 110.9 167.5 304.9 193.8 672.3 290.4 236.2 87.9 418.2 213.2 219.0 1403.5 444.0 158.7 291.5 399.7 182.5 319.0 245.2 429.1 258.1 286.8 405.8 863.0 1202.1 706.0 449.3 199.3 713.5 371.1 375.9 590.5 339.8 92.8 211.8 405.8 313.5 283.1 239.7 289.3 180.5 522.3 436.5 175.0 246.9 849.2 697.4 207.6 269.4 707.3 432.1 188.3 314.7 665.9 527.1 317.5 249.4 225.7 311.1 660.4 353.8 354.9 386.2 569.7 458.9 482.8 55.3 271.3 408.9 629.9 348.3 220.6 390.5 366.1 422.1 246.7 358.1 498.0 450.9 392.3 257.4 680.6 254.6 786.5 582.0 224.3 369.4 412.2 230.9 578.9 539.6 564.4 219.8 405.4 256.9 352.7 319.7 230.7 404.0 309.9 339.4 245.0 265.1 196.6 462.2 278.8 310.3 841.7 415.1 428.7 440.7 519.1 419.2 450.3 430.9 448.3 454.1 418.2 444.0 429.1 415.9 179.5 189.7 21.2 281.7 510.0 525.8 1188.1 512.2 332.2 845.1 868.2 264.6 316.0 600.6 472.6 98.0 562.5 231.3 479.1 1592.6 515.8 4209.7 546.8 326.3 268.7 397.1 215.0 24.5 368.7 1327.3 536.1 99.9 442.3 346.1 242.6 322.0 826.2 1184.1 208.6 33.1 328.7 671.4 583.1 1304.8 18580.2 384.9 735.2 677.7 21.5 1786.8 502.6 192.6 13.6 35.4 484.0 507.9 312.9 189.2 694.7 1861.9 3024.7 800.9 246.0 243.3 244.6 587.1 1310.8 202.4 357.7 467.0 978.1 281.0 186.7 336.4 662.6 GREB1L "C18orf6, FLJ13687, KIAA1772" ENSG00000141449 "GREB1 like retinoic acid receptor coactivator" Q9C091 18 21242242-21525417 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 9.2" "Cell type enhanced" "Detected in many" "Granulosa cells: 95.2;Inhibitory neurons: 39.2;Leydig cells: 46.0;Oligodendrocytes: 252.5" "Cancer enhanced" "Detected in some" "breast cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 50.7;BEWO: 100.9;CACO-2: 45.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA041647, HPA044218" Uncertain Approved Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA041647: AB_2677597, HPA044218: AB_2678859" "unprognostic (1.88e-3)" "unprognostic (9.01e-4)" "unprognostic (2.92e-1)" "unprognostic (2.45e-1)" "unprognostic (5.03e-2)" "unprognostic (3.67e-3)" "unprognostic (3.65e-1)" "unprognostic (1.11e-2)" "unprognostic (1.07e-1)" "unprognostic (1.97e-1)" "unprognostic (4.32e-3)" "unprognostic (2.87e-2)" "unprognostic (3.30e-8)" "unprognostic (4.72e-3)" "unprognostic (1.89e-1)" "unprognostic (8.80e-2)" "unprognostic (1.35e-1)" 2.6 1.4 5.5 0.1 4.3 0.2 3.3 3.5 3.6 1.2 0.0 0.6 0.1 2.6 2.8 0.2 4.4 0.1 5.3 2.6 8.1 0.4 1.8 0.2 0.1 4.0 4.7 3.7 0.1 0.3 1.2 2.1 4.1 1.6 0.1 3.1 0.5 2.9 9.2 1.3 0.5 0.8 1.7 0.0 0.6 6.2 6.4 0.0 3.8 6.8 0.0 0.1 0.7 4.4 0.0 0.9 50.7 0.0 11.4 0.0 100.9 2.4 2.4 4.3 3.8 45.7 3.7 0.1 5.1 7.6 0.1 9.7 19.4 2.4 7.5 0.7 9.3 0.0 13.4 0.4 0.3 0.0 0.0 0.0 0.7 0.1 9.3 0.5 0.0 1.4 0.0 0.3 10.5 3.5 0.2 0.2 4.9 0.4 6.0 0.2 0.0 2.0 4.8 8.7 3.2 0.0 0.1 1.6 0.2 13.2 2.7 0.2 20.9 0.5 2.9 4.9 0.0 0.1 0.7 0.0 2.2 0.0 0.4 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 4.3 3.5 3.6 2.6 8.1 4.0 4.7 4.1 1.7 6.4 4.4 0.4 0.0 0.5 0.7 0.4 0.1 0.1 1.0 0.0 32.3 3.1 1.1 13.4 0.0 1.1 3.7 2.1 3.2 1.8 0.1 0.0 0.2 8.3 2.2 3.4 0.5 0.0 0.0 23.1 0.4 13.2 6.2 0.0 7.0 0.0 95.2 0.0 3.1 0.5 0.0 39.2 0.2 0.0 0.0 1.1 17.9 46.0 0.3 1.8 2.8 0.1 0.8 2.1 8.0 252.5 2.8 0.0 35.7 0.0 0.6 0.3 0.0 2.3 1.6 6.6 2.8 2.3 4.3 5.6 0.0 0.9 1.5 0.3 10.5 1.5 0.2 GRHL3 "SOM, TFCP2L4" ENSG00000158055 "Grainyhead like transcription factor 3" Q8TE85 1 24319357-24364482 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 120.8;skin 1: 53.5;vagina: 47.7" "Group enriched" "Detected in some" 5 "Squamous epithelial cells: 113.5;Suprabasal keratinocytes: 99.3;Urothelial cells: 78.4" "Group enriched" "Detected in many" 4 "cervical cancer: 13.3;head and neck cancer: 16.1;urothelial cancer: 28.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 46.1;HaCaT: 36.6;MCF7: 58.5;OE19: 21.2;RT4: 64.8;SuSa: 33.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA059960 Enhanced Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA059960: AB_2684180" "unprognostic (8.99e-2)" "unprognostic (1.23e-1)" "unprognostic (3.95e-2)" "unprognostic (7.83e-3)" "unprognostic (7.58e-3)" "unprognostic (6.28e-3)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (9.01e-3)" "unprognostic (4.03e-2)" "unprognostic (1.24e-1)" "unprognostic (7.36e-2)" "unprognostic (8.59e-4)" "unprognostic (9.79e-2)" "unprognostic (1.83e-1)" "unprognostic (6.97e-3)" "unprognostic (7.42e-2)" 0.2 0.1 0.4 0.3 0.4 0.1 1.9 1.4 0.6 23.3 0.1 0.1 0.6 0.1 1.6 120.8 0.6 0.7 0.0 0.3 1.3 0.2 0.3 0.1 0.0 3.8 4.6 0.0 0.2 0.9 0.2 1.4 3.4 1.5 0.2 0.1 16.7 1.6 0.1 53.5 0.3 0.0 2.3 0.0 0.5 2.3 0.8 1.0 0.0 0.0 25.1 34.7 47.7 1.9 1.2 2.7 1.0 0.0 0.0 0.0 46.1 0.0 0.0 0.3 0.0 0.0 0.5 0.2 0.0 0.0 0.0 36.6 0.1 3.3 0.0 1.2 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 14.2 0.2 2.7 0.0 0.0 0.0 0.2 0.1 0.0 58.5 0.0 0.2 2.4 21.2 0.0 0.0 0.0 0.2 4.6 64.8 0.3 0.0 0.2 6.3 0.0 33.3 4.2 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.4 1.4 0.6 0.3 1.3 3.8 4.6 3.4 2.3 0.8 1.9 0.0 0.0 0.6 0.0 0.0 14.4 13.2 5.2 8.6 0.0 1.1 0.3 0.5 0.0 6.4 1.8 0.0 4.1 0.0 0.9 0.0 0.4 0.5 3.8 0.1 0.3 0.0 0.0 0.1 0.0 0.8 0.3 0.0 1.3 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.1 2.0 0.3 2.1 0.3 0.0 0.3 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 11.1 0.2 0.0 3.3 0.0 0.0 0.0 0.3 2.6 0.0 113.5 99.3 18.5 0.0 0.0 0.1 78.4 GRIP1 ENSG00000155974 "Glutamate receptor interacting protein 1" Q9Y3R0 12 66347431-67069162 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 16.4" "Cell type enriched" "Detected in many" 7 "Inhibitory neurons: 2829.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "myeloid DC: 4.9" "Lineage enriched" "Detected in many" 5 "dendritic cells: 4.9" "Cell line enhanced" "Detected in many" "BEWO: 44.4;HaCaT: 48.7;REH: 30.7;RT4: 31.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038856 Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA038856: AB_10673297" "unprognostic (6.25e-3)" "unprognostic (6.41e-2)" "unprognostic (1.52e-2)" "unprognostic (8.25e-2)" "unprognostic (1.50e-1)" "unprognostic (5.12e-2)" "unprognostic (2.42e-1)" "unprognostic (4.21e-3)" "unprognostic (4.25e-1)" "unprognostic (1.60e-2)" "unprognostic (1.00e-2)" "unprognostic (4.14e-1)" "unprognostic (2.82e-3)" "unprognostic (7.44e-2)" "unprognostic (1.32e-1)" "unprognostic (7.27e-4)" "unprognostic (8.57e-3)" 0.5 4.3 8.5 2.7 6.6 0.5 3.0 0.0 14.2 1.2 0.0 3.1 1.1 3.5 4.7 7.3 4.2 1.6 2.7 3.9 12.4 3.3 0.3 0.8 0.7 0.7 7.6 1.2 2.0 16.4 3.3 8.2 2.2 4.6 1.7 4.8 6.0 9.3 1.0 9.8 1.9 2.8 0.0 2.6 0.8 6.2 3.0 0.7 5.0 0.6 1.3 2.6 2.0 3.7 11.1 10.1 17.7 2.1 0.0 0.0 44.4 3.2 0.0 5.4 2.5 0.3 3.3 1.4 4.2 0.0 9.5 48.7 4.9 3.3 2.4 0.0 12.0 0.0 0.1 0.3 0.0 1.2 0.1 0.0 8.0 0.0 0.8 8.3 0.0 8.0 0.0 0.1 0.0 4.0 0.4 0.4 16.1 1.4 3.6 30.7 0.1 0.6 5.6 31.0 10.8 1.4 14.8 7.1 1.4 11.3 8.7 1.8 0.0 0.0 12.7 0.1 9.0 1.5 0.3 1.0 12.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.9 0.1 0.1 0.2 0.0 1.0 0.0 0.3 0.0 0.1 8.5 6.6 0.0 14.2 3.9 12.4 0.7 7.6 2.2 0.0 3.0 3.7 0.1 0.0 1.1 74.7 0.1 13.3 2.3 2.9 2.2 5.5 4.1 2.4 3.4 1.5 1.7 7.3 0.0 7.8 0.7 0.3 0.0 2.2 38.5 8.1 2.2 0.4 1.8 0.0 390.2 1.5 4.3 1.1 0.0 13.7 0.0 2.3 0.0 0.0 1.0 47.1 2829.7 0.7 0.0 2.4 1.6 34.0 0.6 2.1 7.2 20.6 1.0 0.5 0.0 158.3 44.4 1.9 0.5 0.7 0.1 3.8 0.2 0.4 1.1 1.8 0.0 1.0 0.6 0.3 1.2 2.3 17.8 16.6 0.8 1.2 0.7 3.1 GRM7 "GLUR7, GPRC1G, mGlu7, MGLUR7, PPP1R87" ENSG00000196277 "Glutamate metabotropic receptor 7" Q14831 3 6770001-7741533 "G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cardiomyopathy, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;parathyroid gland: 4.4" "Group enriched" "Detected in some" 14 "Excitatory neurons: 773.1;Inhibitory neurons: 597.7;Oligodendrocyte precursor cells: 1189.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "SH-SY5Y: 4.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015964 Uncertain Cytosol NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA015964: " "unprognostic (2.04e-2)" "unprognostic (7.03e-3)" "unprognostic (1.43e-1)" "unprognostic (9.37e-2)" "unprognostic (8.48e-3)" "unprognostic (2.58e-1)" "unprognostic (7.30e-2)" "unprognostic (3.50e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.46e-2)" "unprognostic (2.54e-1)" "unprognostic (6.84e-6)" "unprognostic (1.45e-1)" "unprognostic (2.82e-2)" "unprognostic (5.43e-2)" "unprognostic (2.59e-2)" 0.2 2.0 2.8 0.0 2.9 0.0 0.1 0.1 3.8 0.9 0.0 0.1 0.2 0.9 0.0 0.0 0.2 0.0 0.0 3.9 5.1 0.0 0.1 0.1 0.0 2.0 3.0 0.1 0.0 4.4 0.0 0.1 1.7 0.3 0.1 1.1 0.7 0.3 0.0 0.0 0.0 2.3 3.7 0.1 0.0 1.1 5.0 0.3 0.1 0.0 0.0 0.2 0.1 1.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.9 0.1 3.8 3.9 5.1 2.0 3.0 1.7 3.7 5.0 1.7 0.1 0.0 0.0 29.4 0.0 0.1 1.2 0.1 0.0 24.1 0.1 0.5 1.1 4.3 0.7 0.0 8.4 0.0 0.1 0.0 1.9 0.0 32.7 0.1 2.7 0.2 0.0 0.0 773.1 0.0 0.1 1.6 0.0 0.1 1.3 0.1 0.0 0.0 0.1 1.7 597.7 0.0 0.0 0.0 1.2 41.7 0.3 0.4 0.0 13.1 0.1 1.3 0.0 1189.3 56.9 0.0 0.0 0.0 0.0 0.7 0.0 0.1 8.0 3.5 6.6 0.7 0.4 2.7 0.8 0.0 0.0 0.0 0.1 0.5 0.0 0.7 GSC ENSG00000133937 "Goosecoid homeobox" P56915 14 94768223-94770113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.8;breast: 6.8" "Cell type enhanced" "Detected in some" "Adipocytes: 3.5;Breast myoepithelial cells: 2.2;Ductal cells: 3.0;Exocrine glandular cells: 2.4;Fibroblasts: 9.2;Langerhans cells: 2.3;Skeletal myocytes: 2.6;Smooth muscle cells: 4.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "hypothalamus: 1.4" "Immune cell enriched" "Detected in single" 8 "gdT-cell: 3.6" "Lineage enriched" "Detected in single" 18 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HEK 293: 2.0;MCF7: 3.2;REH: 3.3;SH-SY5Y: 3.5;T-47d: 2.5;U-251 MG: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB079923, CAB079924" Supported "Nucleoplasm,Nuclear speckles,Actin filaments" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "Actin filaments" "CAB079923: , CAB079924: " "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-2)" "unprognostic (5.11e-2)" "unprognostic (2.49e-1)" "unprognostic (3.70e-3)" "unprognostic (1.82e-3)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (5.18e-10)" "unprognostic (4.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" 3.8 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.5 0.0 1.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.0 0.0 0.7 0.0 0.0 0.9 0.5 1.2 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 1.6 2.2 0.1 0.3 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 2.4 0.0 9.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 2.6 4.6 0.0 1.2 0.0 0.9 0.0 0.4 0.0 0.0 0.1 GSX2 Gsh2 ENSG00000180613 "GS homeobox 2" Q9BZM3 4 54099523-54102498 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 15 "glioma: 2.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" NA NA "Cluster 65: Brain - Ion transport" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (4.48e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (1.89e-1)" 0.0 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.6 0.2 0.2 0.2 0.2 0.4 0.3 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GTF2H5 "bA120J8.2, C6orf175, FLJ30544, TFB5, TFIIH, TTD, TTD-A, TTDA" ENSG00000272047 "General transcription factor IIH subunit 5" Q6ZYL4 6 158168350-158199344 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 425.8;Proximal tubular cells: 504.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.04e-2)" "unprognostic (2.02e-2)" "unprognostic (2.50e-1)" "unprognostic (8.59e-3)" "unprognostic (3.56e-1)" "unprognostic (1.03e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (1.36e-1)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "unprognostic (5.22e-3)" "prognostic unfavorable (6.11e-4)" "unprognostic (3.13e-1)" "unprognostic (8.46e-2)" "unprognostic (3.58e-3)" "unprognostic (1.33e-2)" 18.0 21.5 18.9 8.3 20.7 5.1 14.1 19.0 32.5 9.1 17.9 9.6 7.4 8.0 20.8 10.1 10.7 7.8 14.0 19.7 20.1 17.7 21.8 7.7 9.9 19.3 18.7 10.2 11.3 13.5 3.2 8.3 19.6 12.7 7.8 18.2 9.0 10.8 27.7 7.2 8.2 9.6 19.7 9.2 8.9 15.1 19.3 15.4 8.4 18.1 9.8 11.3 3.1 21.3 18.5 14.6 24.3 27.5 32.2 40.7 20.8 30.2 26.4 24.7 30.4 10.2 17.4 20.6 48.5 29.6 42.7 13.7 12.0 29.4 29.3 26.6 33.3 28.1 16.1 44.2 29.4 16.1 14.4 36.2 30.2 23.8 29.0 48.5 19.9 29.3 34.3 14.7 46.7 11.1 24.7 39.1 25.2 23.2 17.3 15.6 15.1 32.4 50.3 16.2 18.4 14.7 26.9 26.1 27.0 31.0 21.6 38.1 31.8 18.4 22.5 25.5 39.4 14.1 16.9 30.0 37.1 15.3 38.0 11.6 23.8 16.9 25.4 31.1 22.4 32.7 27.9 25.9 30.6 27.8 33.0 31.7 5.6 31.9 33.4 41.9 35.9 24.3 18.9 20.7 19.0 32.5 19.7 20.1 19.3 18.7 19.6 19.7 19.3 21.3 79.5 44.8 58.4 16.6 49.6 45.5 113.4 232.9 46.1 45.7 91.3 122.2 86.8 88.6 130.4 141.6 16.7 187.8 62.9 44.6 418.7 130.1 425.8 207.5 76.0 61.8 46.6 33.7 15.6 122.4 167.4 93.0 54.0 120.6 65.2 126.7 92.4 180.4 162.0 47.1 18.7 75.1 166.8 80.0 49.2 103.3 112.5 80.3 80.0 11.2 120.6 120.5 117.4 14.1 25.9 92.1 52.7 110.2 24.6 94.3 71.2 504.1 205.0 50.2 72.3 71.8 87.7 227.3 130.6 98.4 63.1 132.8 57.8 177.5 76.1 127.2 GZF1 "dJ322G13.2, ZBTB23, ZNF336" ENSG00000125812 "GDNF inducible zinc finger protein 1" Q9H116 20 23362182-23373062 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024520 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 32: T-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "HPA024520: AB_10963938" "unprognostic (3.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (5.65e-2)" "prognostic unfavorable (9.81e-7)" "unprognostic (8.98e-2)" "unprognostic (2.66e-1)" "unprognostic (8.70e-2)" "unprognostic (3.88e-2)" "unprognostic (1.92e-1)" "unprognostic (3.97e-2)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" "unprognostic (1.13e-3)" "unprognostic (1.45e-1)" 5.9 18.7 9.6 5.5 10.4 31.5 5.0 11.1 10.9 6.0 9.2 6.5 3.9 6.5 5.3 4.4 6.5 5.5 12.4 9.4 9.8 7.7 6.4 6.0 5.2 10.0 12.8 9.2 5.2 6.7 7.9 6.4 9.9 5.9 4.1 10.5 5.0 6.8 9.4 4.7 4.8 5.7 10.6 5.3 5.4 13.3 11.7 5.5 7.0 8.1 4.4 5.8 4.6 10.4 8.2 14.2 8.9 9.0 10.3 10.0 7.1 9.8 9.0 9.9 9.2 10.9 6.4 16.6 8.5 8.5 19.3 14.3 10.3 13.2 11.2 2.8 6.7 15.4 6.0 14.7 13.4 9.3 9.0 10.1 9.6 10.7 16.3 13.8 6.7 11.4 10.6 25.2 14.3 10.9 14.5 11.6 6.6 11.5 19.3 9.5 21.3 11.6 7.4 8.2 13.7 7.8 8.7 15.4 20.9 7.3 10.2 13.4 8.7 16.0 9.2 12.1 10.6 20.5 9.0 14.4 4.7 41.8 8.8 0.0 1.6 0.8 0.7 0.9 0.5 1.0 1.0 1.0 1.6 0.6 0.9 1.0 1.2 0.5 1.2 1.3 0.3 0.9 9.6 10.4 11.1 10.9 9.4 9.8 10.0 12.8 9.9 10.6 11.7 10.4 9.8 6.4 9.6 5.5 12.6 10.8 3.1 3.8 8.6 12.6 6.0 6.9 19.7 1.5 4.7 3.7 18.8 4.9 8.7 3.9 7.9 3.6 18.9 10.4 9.7 8.4 5.4 4.0 6.6 3.3 3.2 8.3 7.1 17.8 13.9 8.2 2.2 5.2 8.7 6.7 7.6 4.2 4.1 13.2 28.8 27.5 9.3 23.9 1.8 1.0 2.5 10.3 5.2 4.5 5.6 4.0 4.6 8.2 11.6 3.2 2.8 3.8 7.7 13.4 0.0 8.8 11.5 20.7 8.9 7.6 8.4 5.6 7.9 14.0 3.7 1.8 HAND1 "bHLHa27, eHand, Hxt, Thing1" ENSG00000113196 "Heart and neural crest derivatives expressed 1" O96004 5 154474972-154478227 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 24.3;intestine: 66.1" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 15.2" "Cancer enriched" "Detected in some" 5 "testis cancer: 2.8" "Region enriched" "Detected in single" 4 "thalamus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "SH-SY5Y: 119.5;SuSa: 212.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040925, HPA075313" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "Nuclear membrane, Nuclear bodies" "HPA040925: AB_10796563, HPA075313: " "unprognostic (2.37e-2)" "unprognostic (8.29e-2)" "unprognostic (2.46e-3)" "unprognostic (7.23e-2)" "unprognostic (5.21e-2)" "unprognostic (6.38e-3)" 0.2 4.7 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.1 3.7 0.0 0.0 0.0 0.0 0.5 24.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 14.3 12.3 0.0 0.0 0.0 0.3 1.5 0.1 0.0 0.0 0.0 7.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 119.5 0.0 0.0 0.0 212.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 15.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.1 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.6 1.7 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.1 1.1 0.0 0.0 0.2 0.0 HARS2 "HARSL, HARSR, HO3" ENSG00000112855 "Histidyl-tRNA synthetase 2, mitochondrial" P49590 5 140691430-140699305 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035941, HPA075303" Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA035941: AB_10671237, HPA075303: " "prognostic unfavorable (6.49e-4)" "unprognostic (3.15e-2)" "prognostic favorable (6.19e-4)" "unprognostic (1.79e-2)" "unprognostic (1.78e-1)" "unprognostic (8.30e-3)" "prognostic unfavorable (2.92e-4)" "unprognostic (7.77e-2)" "unprognostic (1.88e-1)" "unprognostic (5.26e-2)" "unprognostic (1.58e-1)" "unprognostic (2.68e-2)" "unprognostic (1.85e-1)" "unprognostic (5.40e-2)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (1.31e-2)" 19.6 24.6 14.0 13.8 14.2 14.4 18.9 13.7 14.2 22.0 16.8 23.5 16.6 19.5 15.0 20.0 18.4 9.8 27.9 14.0 14.2 23.3 19.3 16.0 15.1 14.1 14.0 21.1 15.6 20.8 20.8 14.2 14.4 20.2 22.3 11.5 17.5 13.4 35.0 21.1 20.9 14.0 13.8 26.9 20.4 14.8 14.3 15.2 19.0 28.4 16.1 21.1 20.6 15.7 20.9 46.2 19.6 50.6 21.9 28.6 32.3 26.3 29.8 36.1 31.4 42.7 25.5 26.3 41.3 29.3 35.5 25.9 27.3 49.4 33.2 26.6 22.4 19.1 45.3 28.6 20.9 26.1 27.1 27.0 32.9 35.3 39.7 29.4 26.5 27.4 18.0 24.1 35.6 26.6 25.7 32.1 22.6 15.7 28.9 25.8 19.9 26.8 33.9 48.1 27.0 38.9 38.1 61.0 54.2 28.5 54.0 25.5 32.5 32.4 17.8 18.2 35.2 23.6 37.0 25.2 25.4 29.5 32.9 37.7 13.1 28.6 19.1 18.9 21.1 16.9 18.4 19.2 14.9 14.8 19.0 20.6 15.1 29.3 15.0 12.1 20.1 13.3 14.0 14.2 13.7 14.2 14.0 14.2 14.1 14.0 14.4 13.8 14.3 15.7 8.6 3.2 5.8 2.6 12.3 3.4 3.7 7.8 9.6 5.5 5.9 5.5 20.4 7.2 7.8 5.5 0.0 20.3 6.6 8.5 13.7 14.9 1.1 5.3 8.0 9.7 7.7 9.9 5.5 16.1 18.7 6.3 13.3 6.4 2.5 11.8 9.7 7.2 10.0 0.0 4.8 8.7 18.3 8.2 6.2 2.3 9.3 7.4 3.6 2.8 12.8 8.3 3.1 6.0 6.2 18.3 12.1 10.5 9.6 4.1 7.2 9.0 8.6 5.6 0.0 4.4 7.0 8.9 14.4 9.5 4.0 14.4 8.0 11.2 11.7 4.4 HCCS "CCHL, MLS" ENSG00000004961 "Holocytochrome c synthase" P53701 X 11111301-11123086 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002946 Approved Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "HPA002946: AB_1079041" "prognostic unfavorable (8.69e-5)" "unprognostic (6.89e-3)" "unprognostic (8.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.34e-1)" "unprognostic (5.44e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (9.18e-2)" "unprognostic (2.73e-1)" "unprognostic (2.52e-2)" "unprognostic (2.10e-2)" "unprognostic (1.60e-1)" "prognostic favorable (6.17e-8)" "unprognostic (2.66e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.93e-2)" 13.9 16.1 6.2 13.7 6.7 20.5 12.6 7.0 8.4 8.4 8.4 21.6 23.1 9.6 7.6 19.3 8.5 10.8 39.0 7.4 6.8 17.6 22.9 11.5 15.6 6.7 6.2 8.3 9.9 25.1 8.3 13.1 6.4 9.5 21.6 13.5 15.2 10.0 64.4 17.6 20.2 12.5 6.2 14.5 15.3 10.2 6.7 13.0 10.8 57.0 17.1 22.3 11.6 6.1 54.3 60.5 31.8 28.5 25.6 25.2 29.2 52.0 43.0 67.8 57.5 70.7 38.5 34.3 26.3 46.1 80.8 49.8 63.2 51.8 70.5 30.8 48.0 34.1 80.8 38.6 47.3 40.9 39.4 24.2 37.4 67.9 46.5 37.9 49.1 26.1 63.1 41.1 46.3 72.5 28.0 31.4 51.5 36.6 70.1 27.3 59.9 65.4 44.0 44.8 20.9 24.2 54.8 58.7 38.2 66.7 45.6 27.1 48.7 42.4 23.6 110.4 47.0 26.9 29.0 47.8 35.5 28.8 42.7 25.6 47.8 30.1 20.2 66.4 19.0 39.0 19.6 18.2 62.2 34.7 17.1 22.1 13.1 19.1 57.4 56.2 23.5 19.0 6.2 6.7 7.0 8.4 7.4 6.8 6.7 6.2 6.4 6.2 6.7 6.1 15.5 6.4 4.8 2.3 20.8 54.8 53.2 57.0 22.8 5.3 16.1 13.7 49.3 17.2 33.3 16.5 0.0 32.9 12.4 44.6 50.9 34.9 13.7 19.0 10.4 21.0 10.8 32.8 3.8 29.3 37.9 17.1 12.8 16.7 13.3 10.4 15.7 18.5 41.8 8.4 4.5 19.2 67.1 21.0 44.1 2.3 13.4 23.5 24.9 1.9 27.9 13.0 7.2 2.0 2.7 68.4 31.9 10.5 18.4 63.5 46.4 36.0 28.9 7.1 6.6 12.5 20.1 24.4 28.4 21.8 46.0 40.9 12.0 15.6 30.2 88.6 HDAC6 "FLJ16239, HD6, JM21, KIAA0901, PPP1R90" ENSG00000094631 "Histone deacetylase 6" Q9UBN7 X 48801377-48824982 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" "Actin-binding, Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003714, CAB004236, HPA026321" Supported Supported Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB004236: AB_627708, HPA003714: AB_1850544, HPA026321: AB_1850546" "unprognostic (9.53e-2)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (2.42e-2)" "unprognostic (2.82e-2)" "unprognostic (4.11e-3)" "unprognostic (2.17e-2)" "unprognostic (1.16e-1)" "unprognostic (7.68e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-3)" "unprognostic (2.33e-2)" "unprognostic (6.10e-2)" "unprognostic (1.47e-1)" "unprognostic (6.60e-2)" "unprognostic (2.34e-1)" "prognostic favorable (3.34e-4)" 21.9 26.0 26.6 14.2 30.7 22.9 23.6 31.1 54.2 29.6 29.8 27.8 17.8 26.8 10.6 24.4 28.2 11.1 26.0 26.7 33.0 57.9 97.3 25.2 15.6 32.6 32.7 32.5 26.3 22.3 45.6 13.8 33.9 24.4 16.1 27.9 21.6 12.2 26.1 21.4 28.0 15.3 28.9 29.4 26.6 53.8 30.6 18.8 27.1 16.1 15.1 23.7 22.8 31.0 31.0 25.7 49.6 19.1 20.2 16.6 33.4 14.4 12.4 27.2 26.2 24.9 25.7 29.9 13.8 17.1 34.6 21.3 30.6 15.5 23.2 27.7 19.1 40.7 32.2 26.0 18.3 19.2 60.4 25.7 25.1 21.5 25.3 24.8 23.5 37.4 45.9 31.9 17.7 10.9 27.0 29.3 18.5 14.2 24.5 23.1 53.5 31.3 15.8 13.3 25.9 25.3 29.5 8.7 17.4 63.4 36.1 17.5 19.1 21.5 26.7 29.3 14.2 29.6 31.3 21.3 21.3 24.0 21.5 0.0 5.1 5.8 4.7 8.3 3.4 3.7 3.3 3.4 7.6 5.3 3.1 2.9 2.5 3.6 11.7 8.3 4.0 4.9 26.6 30.7 31.1 54.2 26.7 33.0 32.6 32.7 33.9 28.9 30.6 31.0 11.4 19.2 25.1 20.9 12.5 7.5 10.2 8.8 6.2 37.6 10.7 10.4 10.6 8.6 17.5 18.4 50.1 11.5 12.6 21.4 19.6 7.9 48.1 10.0 13.0 10.3 14.4 11.4 15.2 7.4 12.3 10.7 21.9 13.2 6.3 22.5 13.6 51.9 11.1 40.4 18.4 15.5 10.2 12.3 9.8 18.4 14.0 13.2 5.4 10.3 12.7 21.9 18.6 17.1 19.0 7.2 13.2 11.3 12.8 7.1 17.8 47.6 12.4 34.0 13.1 15.5 11.1 88.4 41.7 8.6 5.8 9.7 9.7 21.8 16.2 7.2 HDAC8 "HDACL1, KDAC8, MRXS6, RPD3, WTS" ENSG00000147099 "Histone deacetylase 8" Q9BY41 X 72329516-72573101 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Disease variant, FDA approved drug targets, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 120.8;Excitatory neurons: 186.8;Inhibitory neurons: 191.3;Microglial cells: 134.9;Oligodendrocyte precursor cells: 146.8;Oligodendrocytes: 141.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA048560 Supported NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA048560: AB_2680442" "unprognostic (1.42e-1)" "unprognostic (6.62e-3)" "unprognostic (3.20e-2)" "unprognostic (9.24e-3)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (4.64e-2)" "unprognostic (6.03e-2)" "unprognostic (1.58e-1)" "unprognostic (2.81e-2)" "unprognostic (3.17e-2)" "unprognostic (9.68e-2)" "unprognostic (8.42e-2)" "unprognostic (2.33e-3)" "unprognostic (9.10e-2)" "unprognostic (7.15e-3)" "unprognostic (2.12e-3)" 9.2 21.2 16.1 9.8 16.2 17.5 10.3 23.2 19.1 10.3 14.4 9.8 8.5 9.5 22.8 10.2 8.8 9.7 11.9 15.8 19.4 15.1 16.3 9.0 10.9 14.4 13.2 11.2 11.0 11.5 13.4 9.5 15.1 11.2 11.8 16.5 11.4 8.1 10.7 11.5 8.1 10.6 9.7 8.4 10.2 4.2 16.2 8.6 13.0 10.4 10.9 9.7 9.6 20.8 21.0 27.2 20.5 29.9 26.9 24.4 13.5 14.0 21.3 15.9 19.1 20.8 23.3 15.2 38.6 17.2 27.5 14.5 37.0 23.1 21.7 25.9 25.5 21.5 32.7 22.4 14.2 29.9 30.4 22.3 15.4 20.2 15.1 27.6 27.1 20.3 22.4 38.4 24.4 24.8 15.9 53.8 25.9 31.2 38.1 19.7 24.0 26.7 32.8 21.0 16.5 33.0 26.7 19.7 26.9 25.9 12.0 26.9 21.8 15.0 21.3 19.4 13.5 13.5 28.1 18.1 18.5 34.7 20.3 13.8 16.5 28.1 10.5 13.8 8.7 11.9 11.2 9.6 17.2 12.2 8.4 7.5 1.7 10.9 14.5 6.0 15.6 9.8 16.1 16.2 23.2 19.1 15.8 19.4 14.4 13.2 15.1 9.7 16.2 20.8 13.0 3.2 25.7 120.8 14.5 6.1 12.7 15.3 17.1 15.4 9.5 9.7 11.3 12.8 15.7 7.3 43.8 16.4 8.0 7.2 9.8 13.9 0.9 8.8 11.3 12.5 9.1 17.1 186.8 12.4 13.2 14.0 10.7 8.4 12.0 19.2 12.5 10.3 15.8 23.5 191.3 9.3 16.2 8.2 9.0 1.2 11.8 13.3 7.2 134.9 10.9 10.3 8.2 146.8 141.1 11.2 4.7 10.5 19.9 10.6 9.3 22.6 17.4 17.3 26.3 10.1 16.0 4.7 0.8 12.6 6.3 13.5 11.8 15.1 9.7 12.6 HERC1 "p532, p619" ENSG00000103657 "HECT and RLD domain containing E3 ubiquitin protein ligase family member 1" Q15751 15 63608618-63833948 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 458.8;Inhibitory neurons: 338.0;Oligodendrocytes: 201.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049749 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA049749: AB_2680866" "unprognostic (9.72e-2)" "unprognostic (7.51e-2)" "unprognostic (3.43e-1)" "unprognostic (3.80e-1)" "unprognostic (2.35e-1)" "prognostic favorable (4.87e-5)" "unprognostic (1.53e-1)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (2.89e-3)" "prognostic favorable (3.66e-4)" "unprognostic (1.24e-1)" "prognostic favorable (1.36e-6)" "unprognostic (2.87e-1)" "unprognostic (3.36e-2)" "unprognostic (9.04e-3)" "unprognostic (3.94e-1)" 10.5 7.4 8.6 10.3 10.1 27.4 12.7 14.1 20.3 13.0 5.2 11.8 5.3 10.8 6.5 8.1 7.6 9.6 15.2 9.3 0.0 9.1 9.1 10.6 13.7 1.7 0.3 18.5 8.4 22.7 8.8 10.3 1.8 8.6 9.2 18.3 8.8 10.3 30.4 12.1 9.9 12.4 0.0 15.2 10.2 11.5 0.0 25.6 14.0 29.3 12.8 9.2 7.9 22.7 13.5 17.1 19.1 6.6 33.3 21.1 6.4 10.3 13.4 10.7 12.3 10.9 5.3 19.8 9.3 19.8 9.7 14.5 31.2 9.0 14.6 15.4 9.6 42.5 26.4 7.8 5.3 31.6 25.1 15.3 8.5 15.1 14.5 9.3 22.7 13.3 44.0 8.6 9.4 21.7 11.3 6.5 9.3 10.4 8.7 12.2 20.6 11.6 4.4 32.9 17.0 8.4 18.2 12.5 10.5 23.0 6.1 12.7 23.6 13.6 12.6 11.9 13.6 9.4 17.4 13.3 7.8 23.3 4.9 24.4 3.8 8.7 4.9 3.4 3.7 5.9 5.5 4.6 3.4 9.5 5.5 5.4 13.5 2.9 6.7 7.5 7.8 1.8 8.6 10.1 14.1 20.3 9.3 0.0 1.7 0.3 1.8 0.0 0.0 22.7 66.0 6.4 39.5 113.0 44.2 14.9 10.6 16.1 17.1 65.3 19.7 17.1 64.8 17.2 19.9 22.0 66.7 8.8 66.1 11.4 1.9 11.0 28.7 13.5 24.0 44.5 10.2 47.5 458.8 14.1 15.1 28.5 34.7 17.8 50.6 36.5 47.2 21.0 16.2 85.8 338.0 13.1 10.2 43.2 27.4 14.3 27.7 39.2 19.6 137.7 36.0 29.9 35.0 160.4 201.5 11.7 14.7 39.9 44.9 12.7 12.5 15.7 16.6 55.0 6.6 34.4 36.0 43.5 31.3 17.1 15.3 8.9 61.1 31.9 14.4 12.1 HES7 bHLHb37 ENSG00000179111 "Hes family bHLH transcription factor 7" Q9BYE0 17 8120592-8124106 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.1" "Cell type enhanced" "Detected in some" "Melanocytes: 3.6;Smooth muscle cells: 5.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 6.0;Daudi: 6.0;HAP1: 8.3;HDLM-2: 6.5;HeLa: 13.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA072105 Uncertain Approved Nucleoplasm,Nucleoli No NA "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Nucleoli "HPA072105: AB_2686488" "unprognostic (1.98e-1)" "unprognostic (7.91e-3)" "unprognostic (1.16e-3)" "unprognostic (1.08e-2)" "unprognostic (2.11e-1)" "unprognostic (4.99e-2)" "unprognostic (2.84e-1)" "unprognostic (5.13e-2)" "unprognostic (1.32e-2)" "unprognostic (2.04e-1)" "unprognostic (2.74e-1)" "unprognostic (1.22e-5)" "unprognostic (2.99e-2)" "unprognostic (4.79e-2)" "unprognostic (2.69e-2)" "unprognostic (1.55e-1)" 0.3 0.1 0.2 0.0 0.2 0.0 0.3 1.7 1.6 0.7 0.0 0.3 0.0 0.7 0.0 0.3 0.5 0.1 0.9 0.5 0.2 2.1 0.0 0.9 0.1 0.2 0.0 0.9 0.1 0.4 0.4 0.6 0.2 0.4 0.0 0.5 0.6 0.0 0.2 0.5 0.2 0.0 0.3 0.4 0.2 1.1 0.2 0.0 0.5 0.0 0.1 0.2 0.7 0.4 6.0 0.4 0.5 1.8 0.1 0.2 0.2 0.3 0.5 0.5 2.2 0.1 0.3 6.0 0.1 0.0 1.0 0.7 8.3 0.7 0.0 6.5 3.9 0.2 13.9 0.1 0.7 0.7 0.8 0.1 1.1 1.8 4.4 1.0 0.1 1.0 0.2 2.9 0.2 0.1 0.1 0.3 0.2 0.5 1.5 0.6 0.3 1.2 0.2 0.0 0.3 2.9 0.3 0.0 0.3 0.0 0.0 0.0 0.6 0.0 1.3 1.4 2.1 3.9 0.9 0.4 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.7 1.6 0.5 0.2 0.2 0.0 0.2 0.3 0.2 0.4 0.9 0.0 0.0 1.0 0.2 2.2 1.0 0.3 1.2 2.3 2.3 1.7 1.3 0.0 0.1 1.8 0.0 0.0 0.8 0.2 0.0 0.1 1.7 0.2 0.1 1.7 0.0 0.0 1.1 0.0 0.0 1.9 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 2.0 0.3 1.8 0.0 0.0 0.5 3.6 0.0 0.6 0.9 0.0 1.0 0.0 0.0 0.0 0.4 0.1 1.6 0.0 0.1 0.2 0.7 0.0 1.5 5.9 0.1 0.6 1.0 1.6 0.3 0.3 0.0 0.2 0.2 HESX1 "ANF, RPX" ENSG00000163666 "HESX homeobox 1" Q9UBX0 3 57197838-57227606 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Spermatocytes: 36.3" "Cancer enriched" "Detected in many" 4 "testis cancer: 6.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 73.5;U-266/84: 23.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024187 Approved Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "HPA024187: AB_1850620" "unprognostic (6.47e-2)" "unprognostic (1.66e-3)" "unprognostic (5.50e-2)" "unprognostic (1.19e-3)" "unprognostic (5.04e-2)" "unprognostic (2.83e-2)" "unprognostic (3.96e-1)" "unprognostic (3.21e-2)" "unprognostic (1.93e-1)" "unprognostic (3.46e-3)" "unprognostic (9.48e-2)" "unprognostic (2.79e-3)" "unprognostic (1.39e-3)" "unprognostic (4.17e-2)" "unprognostic (3.15e-2)" "unprognostic (4.50e-3)" "unprognostic (1.14e-1)" 1.3 1.8 1.7 1.0 1.7 5.9 2.6 2.2 2.2 1.2 1.4 1.0 1.1 0.9 3.4 1.0 1.1 1.6 1.1 1.7 1.7 2.1 3.8 1.4 1.8 1.9 1.7 1.4 1.8 1.6 1.8 1.1 1.9 1.5 0.8 2.0 1.1 2.0 0.8 4.2 1.0 0.6 1.8 2.2 1.9 6.3 1.8 1.3 2.5 0.6 1.3 0.9 1.0 1.9 1.3 1.2 2.6 4.3 0.4 1.6 0.8 0.1 0.5 0.8 1.4 0.6 3.9 3.4 0.6 0.1 1.0 0.2 1.2 1.4 1.0 2.0 2.9 5.0 1.8 0.4 2.9 1.6 0.5 4.1 1.2 0.4 2.8 2.1 0.7 7.2 0.8 4.3 0.3 0.3 2.2 9.1 73.5 1.1 0.8 0.8 1.6 1.7 3.6 0.7 1.1 3.5 1.0 1.4 2.7 1.2 1.0 7.0 0.5 3.3 1.3 1.0 1.4 12.2 23.7 10.1 1.2 3.1 1.6 0.5 0.8 0.4 0.2 1.6 0.0 0.6 0.2 0.1 0.5 0.5 0.2 0.1 1.4 0.7 0.2 1.8 0.0 0.2 1.7 1.7 2.2 2.2 1.7 1.7 1.9 1.7 1.9 1.8 1.8 1.9 1.0 0.0 0.5 6.5 0.9 0.4 0.6 1.4 0.0 0.3 1.3 1.8 0.8 1.5 0.4 1.8 0.0 1.5 1.7 0.9 0.0 0.4 0.5 1.7 0.7 1.2 0.0 0.0 1.7 0.2 1.1 0.6 0.5 0.4 0.0 1.0 1.4 1.0 2.1 1.7 1.5 0.1 2.0 1.6 0.6 0.4 0.9 2.0 0.0 6.5 1.1 1.6 0.0 3.0 5.1 0.5 0.2 0.4 0.2 0.7 0.7 1.2 0.9 2.6 0.0 0.8 0.5 36.3 7.6 0.3 1.1 0.5 0.7 2.7 0.7 0.4 HHAT "FLJ10724, GUP2, MART-2, MART2, rasp, sit, ski, Skn" ENSG00000054392 "Hedgehog acyltransferase" Q5VTY9 1 210328252-210676296 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 25.8;Excitatory neurons: 47.7;Microglial cells: 20.6;Oligodendrocytes: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Group enriched" "Detected in many" 5 "B-cells: 1.8;dendritic cells: 3.7;T-cells: 1.3" "Cell line enhanced" "Detected in many" "HMC-1: 13.6;LHCN-M2: 11.6;RH-30: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA016462 Approved Approved "Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA016462: AB_2669360" "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" "unprognostic (1.86e-1)" "unprognostic (5.02e-3)" "unprognostic (8.89e-3)" "unprognostic (4.81e-2)" "unprognostic (3.32e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (1.67e-3)" "unprognostic (1.43e-1)" "unprognostic (4.13e-3)" "prognostic favorable (8.47e-7)" "unprognostic (2.55e-1)" "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (5.67e-2)" 2.1 6.5 1.1 0.6 1.1 0.4 3.3 0.3 1.6 3.4 3.6 2.3 1.1 2.5 3.1 2.8 2.8 2.2 2.4 1.0 0.4 4.0 2.7 2.1 0.8 0.7 0.8 2.1 2.3 1.7 3.2 1.3 0.6 4.0 1.3 1.7 4.4 2.0 0.3 3.4 2.5 1.1 0.9 2.2 1.8 2.5 0.6 2.0 4.6 0.2 0.8 3.1 2.9 0.9 0.8 0.9 2.3 1.3 1.0 1.3 4.8 1.2 1.1 1.9 3.1 0.2 0.9 0.0 1.2 0.9 3.1 0.6 0.5 0.5 2.2 1.7 1.2 0.0 0.1 1.1 0.2 0.3 13.6 1.2 2.7 1.6 1.2 3.2 0.3 1.2 0.0 0.0 11.6 1.2 0.6 0.0 0.6 0.7 0.1 1.3 12.4 0.0 7.5 2.6 1.9 7.8 2.1 0.0 6.0 5.9 4.0 0.7 1.7 2.8 8.5 1.6 4.7 3.8 0.2 0.0 1.1 0.8 2.3 0.0 0.3 0.0 0.7 0.4 1.3 1.5 0.9 0.8 0.4 1.8 0.0 0.2 0.0 0.1 0.1 3.7 0.2 0.4 1.1 1.1 0.3 1.6 1.0 0.4 0.7 0.8 0.6 0.9 0.6 0.9 2.0 0.0 2.4 25.8 5.3 2.2 5.7 2.8 6.8 0.5 5.8 2.4 2.4 4.3 1.2 9.2 0.0 4.6 13.9 1.9 3.9 2.6 1.2 8.8 2.6 2.0 0.0 0.4 47.7 0.7 3.6 3.0 2.6 5.8 0.0 4.6 3.6 2.5 1.9 0.0 11.8 2.7 4.1 2.9 0.5 0.5 1.2 1.5 0.0 20.6 1.0 15.6 0.0 17.1 26.0 1.2 2.1 0.4 2.2 3.7 2.3 0.6 12.9 0.5 0.0 1.7 1.7 0.3 1.3 3.1 2.6 2.2 2.8 0.4 2.0 5.2 HK1 ENSG00000156515 "Hexokinase 1" P19367 10 69269984-69401884 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycolysis, Immunity, Inflammatory response, Innate immunity" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Mental retardation, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 374.0;Horizontal cells: 304.5;Late spermatids: 1034.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007043, HPA007044, CAB010052" Supported Supported Mitochondria NA NA 560000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "CAB010052: AB_627721, HPA007043: AB_1850652, HPA007044: AB_1079049" "unprognostic (8.80e-2)" "unprognostic (1.78e-1)" "unprognostic (2.03e-1)" "unprognostic (2.00e-3)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.37e-3)" "unprognostic (7.25e-2)" "unprognostic (1.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.86e-2)" 47.0 24.4 61.0 45.0 65.7 60.3 40.6 58.0 76.6 54.7 64.2 60.1 13.1 41.3 11.2 129.9 37.0 25.7 150.8 69.1 62.7 49.2 8.5 48.1 34.1 56.7 59.8 19.9 12.3 25.0 44.9 49.3 71.1 52.9 31.9 147.6 67.1 53.1 193.5 102.6 29.2 49.8 40.0 40.3 61.6 77.2 53.5 44.9 71.0 146.7 47.6 74.3 80.9 54.1 101.6 56.6 74.2 71.1 81.0 60.4 47.1 98.3 256.5 128.5 138.0 16.3 11.0 7.3 75.8 165.9 92.9 86.2 69.9 220.0 122.0 67.5 54.5 250.0 58.3 1.1 91.7 5.1 181.2 91.5 125.8 184.5 407.6 160.8 135.4 36.8 424.5 51.3 178.7 167.7 29.7 13.1 113.8 51.7 247.0 44.8 45.0 0.6 88.7 117.4 75.7 88.7 112.6 215.4 65.2 104.3 117.7 16.5 140.4 190.5 86.4 106.5 139.6 61.1 42.8 17.4 247.3 130.4 56.1 68.7 88.8 44.6 41.5 125.2 69.0 33.5 47.9 47.6 81.0 19.9 41.7 33.9 20.9 31.2 135.4 9.1 58.1 110.4 61.0 65.7 58.0 76.6 69.1 62.7 56.7 59.8 71.1 40.0 53.5 54.1 26.1 25.6 32.4 38.2 26.5 48.3 50.5 37.8 43.9 83.9 33.1 21.7 130.6 4.3 34.2 27.6 54.2 70.6 14.6 30.3 13.7 28.6 374.0 32.6 28.0 37.9 18.7 104.8 53.8 30.6 93.3 30.3 41.3 34.5 23.4 72.6 26.7 1.1 49.4 304.5 49.8 28.7 44.7 41.7 21.9 1034.1 15.2 51.3 37.4 29.0 35.3 32.9 20.6 14.1 3.5 54.6 11.1 18.4 19.1 29.1 0.7 1.1 30.7 95.5 19.7 22.2 43.1 5.3 6.2 86.0 51.7 118.9 30.5 28.3 19.3 43.5 HMGB3 "HMG2A, HMG4, MGC90319" ENSG00000029993 "High mobility group box 3" O15347 X 150980509-150990771 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" DNA-binding Microphthalmia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 136.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 419.1;Extravillous trophoblasts: 820.7;Syncytiotrophoblasts: 1400.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 11.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HBEC3-KT: 738.7;U-698: 675.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062583, HPA073663" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Nucleoli "HPA062583: AB_2684800, HPA073663: " "unprognostic (2.85e-3)" "unprognostic (2.82e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-2)" "unprognostic (1.16e-1)" "unprognostic (4.60e-2)" "unprognostic (2.66e-3)" "unprognostic (4.54e-3)" "unprognostic (2.70e-2)" "prognostic favorable (9.85e-5)" "unprognostic (6.03e-2)" "unprognostic (1.96e-2)" "prognostic favorable (6.15e-4)" "unprognostic (2.58e-2)" "unprognostic (9.29e-2)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" 8.9 13.7 10.5 19.7 10.5 85.6 15.6 10.4 20.3 34.0 6.5 43.9 27.1 16.4 44.8 26.1 16.9 9.7 11.3 14.5 13.9 19.6 101.4 15.9 25.2 13.0 11.2 5.9 17.2 85.4 4.2 136.6 11.3 13.9 32.4 3.1 23.8 15.9 53.5 19.2 28.1 13.8 10.2 21.2 16.1 40.1 13.4 65.2 14.3 8.9 35.8 18.7 10.5 9.5 263.5 115.5 351.9 184.2 14.5 42.9 437.4 112.9 73.6 127.9 66.1 91.6 106.0 183.0 354.8 87.5 72.3 123.3 324.4 738.7 143.3 125.6 94.7 159.4 110.2 145.6 21.5 243.9 78.0 33.9 171.6 52.5 131.5 32.7 168.3 110.5 84.5 105.4 154.2 201.9 269.3 186.2 209.2 171.0 138.1 325.4 286.3 103.6 95.2 125.3 252.7 164.4 167.4 177.7 56.0 199.3 157.8 158.5 128.0 53.0 123.9 169.9 253.1 94.9 128.7 675.7 63.1 121.3 109.9 0.0 4.3 11.3 0.4 3.0 0.1 2.7 2.0 2.9 6.1 0.5 0.0 0.2 0.7 0.8 5.0 3.1 5.8 2.5 10.5 10.5 10.4 20.3 14.5 13.9 13.0 11.2 11.3 10.2 13.4 9.5 10.4 38.5 31.2 0.7 15.1 23.7 18.9 158.6 12.5 0.5 24.2 16.0 16.0 8.6 123.5 31.3 2.1 419.1 4.5 32.1 37.2 82.4 232.3 61.9 18.9 19.6 65.7 136.1 1.3 86.5 820.7 17.6 22.4 55.9 8.2 44.2 13.6 84.4 101.0 0.0 3.7 37.0 219.7 20.8 43.7 75.9 3.7 22.1 21.4 2.8 23.6 4.1 1.0 1.5 0.5 91.5 35.7 3.4 47.1 27.5 31.8 66.5 113.3 1.8 0.0 39.8 29.0 22.7 50.2 41.1 20.3 1400.2 10.1 10.4 60.7 18.5 HMX1 "H6, NKX5-3" ENSG00000215612 "H6 family homeobox 1" Q9NP08 4 8846076-8871839 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cataract, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 1.6;retina: 2.3;testis: 1.3" "Group enriched" "Detected in some" 13 "Horizontal cells: 267.5;Muller glia cells: 247.9" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 5.1;EFO-21: 2.9;HEK 293: 5.5;SH-SY5Y: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 77: Retina - Visual perception" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (6.11e-2)" "unprognostic (1.63e-2)" "unprognostic (2.97e-1)" "unprognostic (6.35e-2)" "unprognostic (7.94e-2)" "unprognostic (9.36e-2)" "unprognostic (1.97e-1)" 0.0 0.0 1.2 0.0 1.0 0.0 0.0 1.6 1.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.0 1.5 1.6 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.0 1.6 1.2 1.0 1.0 1.5 1.6 1.4 1.1 1.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 0.0 0.1 0.6 0.0 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 267.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 247.9 0.0 6.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.2 0.1 0.1 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 HNRNPK "CSBP, HNRPK, TUNP" ENSG00000165119 "Heterogeneous nuclear ribonucleoprotein K" P61978 9 83968083-83980616 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, Ribonucleoprotein, RNA-binding" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004435, HPA007644, CAB016225, HPA044105" Supported Enhanced Nucleoplasm NA NA 7100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004435: AB_627734, CAB016225: , HPA007644: AB_1079077, HPA044105: AB_2678812" "unprognostic (4.84e-2)" "unprognostic (4.69e-1)" "unprognostic (1.15e-2)" "unprognostic (8.42e-3)" "unprognostic (2.78e-2)" "unprognostic (9.83e-3)" "prognostic unfavorable (6.68e-5)" "unprognostic (3.46e-3)" "unprognostic (8.11e-2)" "unprognostic (1.47e-1)" "unprognostic (8.85e-3)" "unprognostic (2.81e-2)" "unprognostic (2.76e-3)" "unprognostic (2.23e-3)" "unprognostic (6.50e-2)" "unprognostic (4.59e-1)" "unprognostic (2.82e-1)" 283.6 308.1 186.1 326.2 197.1 637.3 265.3 202.4 236.6 264.5 227.4 270.2 287.0 297.0 227.3 276.8 269.7 243.8 275.8 188.8 220.3 279.2 346.8 240.4 401.9 203.1 187.8 317.5 247.4 350.8 198.2 325.8 203.0 251.3 277.5 342.2 242.2 251.4 315.3 256.1 282.9 287.6 205.7 298.3 250.1 183.4 194.4 548.5 297.2 312.9 423.7 351.2 230.7 241.0 926.1 624.2 1048.4 625.7 492.2 540.7 840.0 634.1 785.0 778.2 726.4 527.0 641.2 1087.2 425.8 671.1 673.8 689.5 1061.5 772.9 941.8 753.7 624.2 765.1 511.9 754.6 648.7 958.6 726.5 554.6 577.4 665.6 876.1 583.7 806.1 605.5 792.8 541.4 776.4 809.0 1198.4 652.1 934.7 929.3 599.3 1030.2 835.0 727.6 760.3 747.6 677.1 802.6 669.6 703.8 645.5 721.8 698.6 801.6 665.8 537.9 631.7 552.7 844.2 564.7 795.5 784.6 514.3 762.6 779.5 582.0 438.9 559.2 302.2 419.8 378.9 347.8 346.6 348.7 457.5 324.4 354.8 327.2 546.1 477.9 429.1 270.8 457.4 1012.5 186.1 197.1 202.4 236.6 188.8 220.3 203.1 187.8 203.0 205.7 194.4 241.0 354.7 205.1 270.0 58.4 398.4 506.0 540.7 421.5 313.0 180.9 281.6 203.3 195.0 230.2 322.4 263.0 89.6 585.3 379.9 288.1 395.2 448.2 43.4 326.2 329.0 331.7 387.0 447.9 45.9 368.3 738.5 323.4 233.9 384.2 336.8 300.0 260.9 356.6 388.4 156.5 51.2 379.2 307.2 352.9 412.9 45.4 334.6 333.4 327.3 58.1 448.9 362.5 338.8 71.9 116.2 397.0 282.7 321.2 281.0 353.3 260.0 416.7 308.1 182.6 276.1 340.9 479.7 345.9 241.7 309.5 448.7 728.5 368.6 334.9 406.9 453.2 HOXA1 "HOX1, HOX1F" ENSG00000105991 "Homeobox A1" 7 27092993-27096000 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "urinary bladder: 5.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 7.4;Enteroendocrine cells: 3.0;Kupffer cells: 3.2;Squamous epithelial cells: 5.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 6 "intermediate monocyte: 4.5;NK-cell: 4.8;non-classical monocyte: 7.0" "Group enriched" "Detected in many" 6 "monocytes: 7.0;NK-cells: 4.8" "Cell line enhanced" "Detected in many" "HMC-1: 14.1" "Region enriched" "Detected in single" 7 "pons and medulla: 1.0" "Region enhanced" "Detected in some" "spinal cord: 2.6" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 39: CACO-2 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (7.39e-2)" "unprognostic (1.26e-3)" "unprognostic (1.05e-1)" "unprognostic (2.17e-4)" "unprognostic (2.79e-2)" "prognostic unfavorable (6.73e-5)" "unprognostic (4.70e-2)" "unprognostic (2.72e-2)" "unprognostic (6.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.11e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-4)" "unprognostic (2.03e-1)" "unprognostic (2.82e-1)" "unprognostic (5.77e-3)" "unprognostic (1.17e-1)" 0.6 0.5 0.0 0.7 0.0 0.3 0.6 0.0 0.0 0.4 0.0 1.1 0.3 0.4 1.9 2.9 0.8 0.3 0.0 0.0 0.0 0.9 0.2 0.3 1.3 1.1 0.0 1.6 0.0 1.1 0.0 0.1 0.5 0.5 1.0 0.0 0.0 0.4 0.2 2.2 1.1 0.3 0.7 1.2 0.7 0.1 0.0 0.7 0.1 0.0 1.1 5.3 0.5 0.7 6.3 2.6 0.2 3.4 0.0 0.0 5.6 0.8 3.5 2.2 2.6 13.8 3.8 4.2 7.9 2.1 8.5 13.2 4.6 3.7 1.6 0.3 13.9 5.5 0.2 0.1 0.7 4.8 14.1 2.4 3.8 2.6 5.5 0.0 3.5 4.2 6.1 0.0 4.7 0.1 0.0 7.7 0.0 2.4 0.6 5.2 1.6 0.0 7.6 6.0 0.4 0.0 3.0 0.0 3.8 4.4 0.0 2.2 2.7 0.5 5.4 4.1 1.1 0.0 0.0 2.0 2.1 8.1 5.8 0.7 0.2 0.5 0.8 4.5 0.8 0.3 0.9 0.8 0.8 0.0 0.3 0.8 0.2 4.8 7.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.5 0.7 0.0 0.7 0.9 0.0 0.0 0.0 0.2 2.3 1.4 0.3 7.4 0.0 0.6 1.8 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.2 0.4 0.8 3.0 0.0 0.0 0.0 1.0 1.1 0.0 0.0 2.5 0.1 2.2 0.0 0.1 0.0 0.0 2.1 0.0 3.2 0.4 0.0 0.0 1.1 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.1 0.3 0.0 1.3 0.2 1.2 0.9 1.2 0.0 0.0 0.3 1.5 0.1 0.8 5.8 1.1 0.0 1.4 0.3 0.9 2.1 HOXA11 "HOX1, HOX1I" ENSG00000005073 "Homeobox A11" P31270 7 27181157-27185232 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 44.8;endometrium 1: 96.7;smooth muscle: 41.2" "Cell type enriched" "Detected in some" 19 "Endometrial stromal cells: 116.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.5;HEK 293: 44.0;THP-1: 34.7;U-937: 43.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 36 "spinal cord: 3.5" "HPA006770, HPA035623" Enhanced Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 32: U-937 - Innate immune response" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "HPA006770: AB_2667672, HPA035623: AB_10601576" "unprognostic (5.95e-2)" "unprognostic (9.23e-2)" "unprognostic (3.07e-2)" "unprognostic (2.70e-2)" "unprognostic (6.29e-2)" "unprognostic (9.78e-2)" "unprognostic (2.82e-3)" "unprognostic (4.36e-2)" "unprognostic (1.61e-2)" "unprognostic (3.05e-2)" "unprognostic (2.08e-3)" "unprognostic (1.73e-2)" "prognostic unfavorable (2.57e-5)" "unprognostic (2.17e-2)" "unprognostic (6.90e-2)" "unprognostic (2.03e-2)" "unprognostic (2.56e-1)" 3.5 0.7 0.0 1.4 0.0 0.0 0.4 0.0 0.0 44.8 0.0 23.1 0.0 96.7 0.0 0.0 1.3 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 10.0 0.0 14.7 3.9 0.0 0.1 9.6 7.9 1.5 0.2 41.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 17.0 10.4 0.0 4.8 0.3 0.0 13.1 15.2 11.1 0.0 26.8 32.5 18.9 13.8 0.3 1.7 0.0 6.1 23.5 0.1 3.2 16.3 0.0 14.7 1.6 44.0 5.7 11.2 0.7 0.9 12.5 1.7 6.5 0.6 0.1 0.0 0.0 14.1 1.1 0.4 0.0 2.2 0.4 0.0 9.4 0.0 4.4 13.1 0.7 0.0 0.3 9.6 8.1 5.6 0.0 6.7 0.0 2.0 3.6 1.2 34.7 0.0 0.2 12.9 3.2 1.5 0.0 0.0 0.0 0.2 43.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.8 0.0 0.1 0.3 1.1 5.9 0.0 0.8 4.0 116.8 1.3 5.3 0.0 0.0 0.0 0.1 3.6 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 2.8 0.2 0.2 0.0 0.0 0.0 0.9 5.8 1.2 0.1 0.0 0.0 0.0 0.6 0.1 1.1 1.3 HOXA13 "HOX1, HOX1J" ENSG00000106031 "Homeobox A13" P31271 7 27193503-27200091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 23.1;placenta: 17.1;prostate: 22.3;seminal vesicle: 23.3" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 41.3" "Cancer enhanced" "Detected in many" "prostate cancer: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 26.9;HEK 293: 37.3;PC-3: 18.4;RT4: 42.1;THP-1: 18.2;U-937: 20.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046098, HPA069061" Supported "Nucleoplasm,Mitotic chromosome,Intermediate filaments" Yes NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Mitotic chromosome, Intermediate filaments" "HPA046098: AB_2679536, HPA069061: " "unprognostic (7.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (8.04e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-2)" "unprognostic (9.22e-3)" "unprognostic (7.30e-3)" "unprognostic (8.39e-3)" "unprognostic (1.54e-1)" "unprognostic (1.42e-11)" "unprognostic (2.58e-3)" "unprognostic (1.38e-1)" "unprognostic (1.72e-1)" "unprognostic (1.36e-2)" 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.1 0.0 9.9 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 0.0 22.3 11.9 0.0 0.0 23.3 2.1 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.1 14.1 0.0 2.2 1.6 0.0 2.5 0.2 0.0 0.1 13.2 14.4 5.1 3.3 2.8 0.2 0.0 1.6 6.2 0.7 0.0 26.9 0.0 4.3 0.0 37.3 1.9 6.9 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 8.7 0.0 11.8 18.4 2.7 0.6 0.0 0.1 42.1 0.7 0.0 3.3 0.0 0.3 2.0 0.0 18.2 0.0 0.5 4.5 0.3 0.1 0.0 0.0 0.0 0.0 20.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 41.3 0.0 0.0 0.6 0.1 4.0 1.1 8.4 0.0 0.0 0.0 0.1 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.1 2.8 0.5 0.0 0.0 0.1 0.1 0.1 0.0 10.3 3.1 HOXA2 HOX1K ENSG00000105996 "Homeobox A2" O43364 7 27100354-27102686 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 23.3;Breast myoepithelial cells: 3.8;Enteroendocrine cells: 4.8;Hepatic stellate cells: 6.4;Squamous epithelial cells: 6.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 16 "medulla oblongata: 4.5;pons: 3.3;spinal cord: 4.7;white matter: 4.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 14.5;HaCaT: 6.2;RPTEC TERT1: 4.9" "Region enriched" "Detected in single" 36 "pons and medulla: 5.8" "Group enriched" "Detected in some" 17 "medulla oblongata: 4.2;pons: 1.1;spinal cord: 3.0" HPA078220 Approved Nucleoplasm,Vesicles Yes NA "Cluster 1: Neutrophils - Mixed function" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Vesicles" "HPA078220: AB_2686880" "unprognostic (7.30e-2)" "unprognostic (4.90e-4)" "unprognostic (2.81e-1)" "unprognostic (7.43e-4)" "unprognostic (1.44e-1)" "unprognostic (2.01e-2)" "unprognostic (1.17e-1)" "unprognostic (2.96e-1)" "unprognostic (1.85e-3)" "unprognostic (1.48e-2)" "unprognostic (1.84e-1)" "unprognostic (1.58e-2)" "unprognostic (4.98e-9)" "unprognostic (1.34e-1)" "unprognostic (1.33e-1)" "unprognostic (9.36e-2)" "unprognostic (1.28e-2)" 1.9 1.0 0.0 0.6 0.0 0.0 1.6 0.0 0.0 1.6 0.0 3.3 0.9 2.0 5.1 2.3 4.1 1.0 0.2 0.0 0.0 4.4 0.2 1.7 0.2 4.5 0.2 0.6 0.3 5.7 0.0 0.0 3.3 1.7 1.8 0.0 0.0 2.1 0.7 1.6 2.6 0.9 4.7 1.2 2.2 0.1 0.1 1.8 0.8 3.0 0.6 2.0 0.9 4.3 1.1 0.6 4.0 14.5 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.6 3.4 0.1 1.5 0.1 1.8 6.2 0.2 0.0 0.0 0.0 2.0 0.0 0.1 0.2 1.8 0.1 0.3 0.8 0.0 3.1 3.1 0.0 2.5 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.9 1.0 0.7 0.0 4.9 0.5 0.9 0.0 0.2 0.0 0.9 0.2 0.0 0.0 2.5 0.0 0.2 1.1 0.5 0.0 0.0 0.1 0.0 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.2 3.3 4.7 0.1 4.3 1.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 23.3 0.0 1.2 3.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.1 1.3 2.5 4.8 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 6.4 0.1 0.1 0.0 0.0 1.3 0.0 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.1 1.1 0.5 0.0 0.0 0.0 1.0 1.9 0.0 0.0 6.3 0.3 0.0 0.1 0.0 1.7 0.7 HOXB1 "HOX2, HOX2I" ENSG00000120094 "Homeobox B1" P14653 17 48528526-48531011 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 2.2" "Cancer enriched" "Detected in single" 15 "testis cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044576 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA044576: AB_10794501" "unprognostic (1.80e-2)" "unprognostic (9.50e-3)" "unprognostic (8.22e-2)" "unprognostic (1.22e-1)" "unprognostic (6.26e-2)" "unprognostic (2.40e-2)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (6.74e-2)" "unprognostic (1.45e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.2 HOXC13 "HOX3, HOX3G" ENSG00000123364 "Homeobox C13" P31276 12 53938831-53946544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "skin 1: 9.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.7;Breast myoepithelial cells: 3.0;Spermatogonia: 1.2;Suprabasal keratinocytes: 2.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 31.2;HaCaT: 66.1;SK-BR-3: 36.0;T-47d: 28.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA051634 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "HPA051634: AB_2616459" "unprognostic (5.16e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (2.27e-3)" "unprognostic (2.78e-2)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (4.04e-2)" "unprognostic (1.53e-1)" "unprognostic (9.77e-2)" "unprognostic (9.74e-9)" "unprognostic (2.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.68e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 15.7 10.5 0.0 31.2 0.5 0.0 18.4 1.9 4.4 2.8 1.5 2.7 0.5 0.0 0.4 0.0 2.0 66.1 8.0 2.1 1.6 0.0 6.4 0.0 8.4 0.0 0.0 0.0 6.6 0.0 15.4 0.0 6.0 0.0 0.0 0.1 11.8 0.0 11.5 20.1 0.0 0.0 0.3 6.6 2.7 0.0 0.4 0.0 0.0 6.0 0.0 0.0 10.4 36.0 4.9 7.4 28.1 0.1 0.0 0.1 13.1 0.2 4.2 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.7 3.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.2 0.0 2.4 0.1 0.0 0.0 0.0 0.0 HOXD10 "HOX4, HOX4D" ENSG00000128710 "Homeobox D10" P28358 2 176108790-176119937 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 20.6;endometrium 1: 35.9;vagina: 25.0" "Cell type enhanced" "Detected in some" "Adipocytes: 13.0;Collecting duct cells: 14.7;Distal enterocytes: 10.6;Distal tubular cells: 15.6;Endometrial stromal cells: 25.3;Endothelial cells: 13.5;Enteroendocrine cells: 24.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 12.0;HEK 293: 40.3;RPTEC TERT1: 32.3;SCLC-21H: 11.8;SiHa: 18.4;U-251 MG: 14.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 66 "spinal cord: 6.6" HPA065871 Approved "Nucleoplasm,Cytosol,Cytoplasmic bodies" No NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "Cytosol, Cytoplasmic bodies" "HPA065871: AB_2685573" "unprognostic (4.29e-3)" "unprognostic (2.51e-1)" "unprognostic (2.98e-3)" "unprognostic (1.69e-1)" "unprognostic (1.80e-3)" "unprognostic (6.82e-2)" "unprognostic (1.04e-5)" "unprognostic (1.19e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-1)" "unprognostic (5.24e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (2.15e-3)" "unprognostic (4.57e-2)" "unprognostic (4.86e-1)" "unprognostic (1.27e-1)" 2.0 0.1 0.0 0.5 0.0 0.0 2.6 0.0 0.0 20.6 0.0 18.7 0.0 35.9 0.5 0.5 4.1 0.1 0.0 0.0 0.0 19.9 0.0 0.1 0.5 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 16.8 5.8 0.0 0.1 6.7 0.1 1.5 0.1 18.1 0.0 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.2 2.2 25.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 4.2 6.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.1 12.0 0.0 0.0 0.5 0.0 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.9 0.0 32.3 0.0 11.8 3.1 18.4 0.0 0.1 2.2 0.0 0.0 2.7 0.0 2.1 1.0 14.4 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 13.0 0.0 0.0 0.0 0.0 0.9 6.2 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 14.7 0.0 0.0 0.1 10.6 15.6 0.0 0.0 1.2 25.3 13.5 24.1 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 0.0 0.0 0.8 0.2 1.8 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.5 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.1 1.1 0.0 0.2 0.0 4.4 2.9 HOXD13 "HOX4I, SPD" ENSG00000128714 "Homeobox D13" P35453 2 176092721-176095944 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "cervix: 14.2;intestine: 18.2;prostate: 9.7;seminal vesicle: 16.3;vagina: 17.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 12.4;Distal enterocytes: 5.5;Enteroendocrine cells: 29.0;Intestinal goblet cells: 9.1;Paneth cells: 5.5;Prostatic glandular cells: 6.3;Undifferentiated cells: 9.9;Urothelial cells: 6.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.4;HEK 293: 53.3;HL-60: 61.7;JURKAT: 16.7;NB-4: 36.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA064064 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA064064: AB_2685186" "unprognostic (2.04e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.95e-5)" "unprognostic (2.52e-3)" "unprognostic (7.25e-2)" "unprognostic (2.08e-2)" "unprognostic (4.62e-2)" "unprognostic (1.77e-1)" "unprognostic (4.66e-1)" "unprognostic (1.01e-2)" "unprognostic (2.82e-4)" "unprognostic (4.95e-2)" "unprognostic (3.70e-2)" "unprognostic (9.98e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.2 0.0 18.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 9.7 7.6 0.0 0.0 16.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.1 2.2 4.7 0.0 0.0 0.0 0.0 0.0 5.1 0.0 18.4 0.0 2.8 0.0 53.3 8.3 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 3.9 0.0 0.0 0.0 0.0 36.3 1.9 0.0 3.0 0.0 0.2 0.0 0.0 0.4 15.2 3.7 3.8 0.0 8.9 0.2 0.0 0.0 0.0 1.8 0.0 0.8 5.1 0.0 0.0 0.0 2.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.9 0.0 0.1 0.1 29.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.4 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 9.9 6.7 HPDL "4-HPPD-L, GLOXD1, MGC15668" ENSG00000186603 "4-hydroxyphenylpyruvate dioxygenase like" Q96IR7 1 45326895-45328679 "Human disease related genes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 29.1;Gastric mucus-secreting cells: 8.2;Undifferentiated cells: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 111.7;HL-60: 34.2;NB-4: 42.8;SK-BR-3: 72.5" "Low region specificity" "Detected in many" "HPA031997, HPA057346" Supported Nucleoplasm,Mitochondria No NA "Cluster 39: Non-specific - mRNA processing" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Nucleoplasm "HPA031997: AB_10602909, HPA057346: AB_2683415" "prognostic favorable (1.81e-4)" "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (1.02e-2)" "unprognostic (6.71e-2)" "unprognostic (3.93e-3)" "unprognostic (1.25e-1)" "unprognostic (1.63e-1)" "prognostic favorable (1.03e-4)" "unprognostic (1.08e-3)" "unprognostic (2.52e-2)" "unprognostic (6.66e-2)" "unprognostic (1.26e-2)" "unprognostic (1.00e-1)" "unprognostic (3.03e-2)" "unprognostic (1.43e-1)" 0.4 0.2 1.0 1.3 1.3 1.8 0.4 3.1 1.0 1.2 0.0 3.7 2.4 0.6 0.0 2.2 0.6 0.0 0.3 0.9 0.9 0.6 0.1 0.3 1.0 1.3 1.2 0.6 0.3 0.0 0.3 2.1 1.3 0.6 2.8 0.4 1.0 0.2 1.6 0.8 2.5 0.3 0.8 1.8 3.4 0.3 1.3 1.2 0.6 0.6 0.9 0.5 1.1 1.3 0.1 1.1 0.5 0.1 0.1 0.4 111.7 1.5 0.0 2.0 0.4 28.7 7.7 5.8 0.3 1.5 0.0 7.0 0.0 0.4 0.7 0.2 0.3 0.6 13.4 0.0 0.7 34.2 0.9 1.1 0.2 1.2 0.0 0.1 2.2 0.2 0.0 5.2 0.2 14.6 22.1 42.8 0.5 23.0 0.0 6.6 0.1 19.4 0.4 0.4 22.2 1.5 14.6 72.5 11.4 1.6 0.2 6.3 1.0 0.0 0.3 1.3 0.0 0.9 0.6 21.3 0.1 0.1 1.4 0.0 0.0 0.0 0.1 0.0 0.3 0.6 0.1 0.2 0.2 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.1 0.1 1.0 1.3 3.1 1.0 0.9 0.9 1.3 1.2 1.3 0.8 1.3 1.3 0.1 0.0 0.0 2.9 1.0 0.1 2.3 0.5 1.2 0.2 0.7 1.0 0.4 0.0 0.1 0.0 0.0 29.1 0.3 3.0 3.9 0.4 0.2 0.1 1.5 0.7 1.2 4.2 0.0 0.0 5.8 0.8 8.2 0.2 0.0 0.9 0.4 0.1 2.5 0.0 0.2 3.3 0.0 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.5 0.0 1.8 1.9 0.0 5.2 2.2 0.4 0.3 0.0 0.4 0.0 0.6 0.8 0.0 1.9 2.1 1.1 5.1 0.4 1.2 7.6 1.5 HPGD SDR36C1 ENSG00000164120 "15-hydroxyprostaglandin dehydrogenase" P15428 4 174490175-174523154 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 235.0;urinary bladder: 376.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 457.8;Extravillous trophoblasts: 701.7;granulocytes: 864.5;Proximal enterocytes: 500.6;Urothelial cells: 922.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 52.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 123.7;T-reg: 45.0" "Group enriched" "Detected in many" 73 "granulocytes: 123.7;T-cells: 45.0" "Cell line enhanced" "Detected in many" "A549: 157.8;ASC diff: 110.6;HEL: 355.0;OE19: 102.1;RT4: 565.7;SuSa: 121.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004919, HPA005679" Enhanced Supported Nucleoplasm,Cytosol No NA 20000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoplasm "HPA004919: AB_1079081, HPA005679: AB_1079080" "unprognostic (1.23e-3)" "unprognostic (1.61e-1)" "unprognostic (5.96e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (2.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.28e-2)" "unprognostic (3.54e-3)" "unprognostic (2.34e-2)" "prognostic favorable (3.20e-4)" "unprognostic (2.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.37e-4)" "unprognostic (2.33e-2)" 9.2 16.5 1.0 11.4 0.7 2.7 159.9 0.5 1.2 32.2 8.7 60.9 152.2 45.5 36.5 81.6 13.4 24.9 1.6 1.2 2.8 60.2 210.8 91.0 5.5 1.4 2.0 1.1 2.6 85.3 2.1 99.1 1.0 10.2 57.4 1.0 7.7 4.0 2.5 39.8 117.3 63.7 0.8 10.3 235.0 1.6 2.2 12.2 1.7 3.0 26.6 376.0 83.0 0.7 0.0 157.8 0.0 0.0 110.6 5.4 0.4 0.0 0.0 0.0 0.4 45.1 0.2 0.1 0.0 0.0 0.2 14.2 16.0 0.0 0.0 0.3 2.9 355.0 10.8 0.3 0.0 2.1 0.9 5.6 2.6 0.0 0.1 0.1 0.0 22.6 0.2 0.0 0.0 0.3 1.2 0.3 1.4 102.1 7.4 16.3 0.3 1.3 36.2 565.7 0.9 0.4 0.0 1.3 3.5 121.3 0.1 0.0 0.3 0.0 0.2 0.1 0.0 28.4 0.0 0.1 0.3 0.2 0.0 123.7 0.3 16.6 9.9 0.0 15.6 0.4 5.2 4.5 0.7 0.2 1.6 4.0 1.3 1.1 0.0 0.0 45.0 3.0 1.0 0.7 0.5 1.2 1.2 2.8 1.4 2.0 1.0 0.8 2.2 0.7 3.4 16.0 33.0 0.0 4.3 17.3 80.8 6.9 45.5 3.3 14.5 6.7 0.8 35.8 23.6 22.0 0.0 48.5 38.5 457.8 21.5 7.4 1.4 5.7 5.4 18.2 8.4 17.2 0.8 94.5 701.7 25.3 196.7 36.4 864.5 1.5 13.9 245.7 21.4 0.0 9.7 60.7 0.0 14.8 19.5 0.5 19.9 29.2 76.5 5.6 2.9 0.0 10.3 0.0 4.1 42.4 254.7 0.0 50.2 76.8 500.6 131.1 4.4 0.8 0.0 2.4 3.7 0.5 1.0 53.4 22.4 56.6 42.7 65.0 58.9 922.8 HR "ALUNC, AU" ENSG00000168453 "HR lysine demethylase and nuclear receptor corepressor" O43593 8 22114419-22133384 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Oxidoreductase" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.9;skin 1: 52.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 91.4;Cone photoreceptor cells: 33.3;Distal enterocytes: 27.5;Gastric mucus-secreting cells: 26.5;Paneth cells: 31.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 21.2;HaCaT: 81.7;OE19: 39.9;SiHa: 28.8;T-47d: 30.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054888 Supported Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA054888: AB_2682630" "unprognostic (9.11e-2)" "unprognostic (2.12e-2)" "unprognostic (7.32e-2)" "unprognostic (4.68e-3)" "unprognostic (6.49e-2)" "unprognostic (2.80e-1)" "unprognostic (1.53e-2)" "unprognostic (2.45e-1)" "unprognostic (1.23e-1)" "unprognostic (1.21e-1)" "unprognostic (1.90e-1)" "unprognostic (1.75e-1)" "unprognostic (2.27e-2)" "unprognostic (8.00e-3)" "unprognostic (1.81e-1)" "unprognostic (2.32e-1)" "unprognostic (2.28e-2)" 2.4 1.0 4.3 1.8 6.7 0.0 2.7 7.8 14.5 3.8 0.0 9.0 4.8 1.6 0.1 20.9 1.1 1.3 2.3 3.1 4.8 0.6 0.4 0.8 0.3 11.3 9.0 0.6 0.5 0.0 2.7 0.1 12.0 3.8 3.2 1.8 5.1 4.2 0.7 52.7 4.7 1.5 2.4 0.5 7.7 5.3 8.8 0.6 4.3 0.9 1.2 3.0 11.7 11.5 1.9 21.2 0.0 0.0 0.2 0.6 0.1 0.1 0.1 0.0 0.0 0.0 2.6 0.0 20.7 1.5 1.0 81.7 0.0 2.0 0.0 0.0 0.0 0.0 17.8 0.1 4.7 0.0 0.1 4.1 12.9 0.0 1.4 1.3 0.0 2.1 0.0 0.2 0.0 12.7 1.5 0.3 0.0 39.9 16.3 1.9 0.0 0.5 0.3 5.7 1.0 4.7 28.8 6.4 6.5 0.3 30.0 0.0 0.0 0.4 17.2 0.0 0.9 0.0 0.0 0.0 0.2 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 6.7 7.8 14.5 3.1 4.8 11.3 9.0 12.0 2.4 8.8 11.5 1.9 0.0 0.0 1.3 0.0 12.0 4.5 4.3 10.8 91.4 4.0 3.9 2.7 0.0 1.4 1.8 33.3 0.1 0.1 27.5 0.0 0.1 0.3 1.6 1.2 0.6 7.8 0.0 8.7 0.7 0.2 2.1 26.5 2.1 0.0 0.3 1.8 0.3 0.0 10.1 3.9 8.1 0.0 0.0 2.1 1.9 3.4 0.1 21.4 0.0 0.0 3.2 0.0 2.0 9.2 0.3 31.2 7.2 0.0 3.0 11.0 0.1 1.3 8.8 0.0 5.8 3.3 0.1 0.3 15.5 17.8 0.8 0.3 0.2 19.5 6.8 HRAS HRAS1 ENSG00000174775 "HRas proto-oncogene, GTPase" P01112 11 532242-537287 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 145.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002015, HPA049830, HPA070222" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "CAB002015: , HPA049830: AB_2680903, HPA070222: " "unprognostic (3.06e-2)" "unprognostic (2.98e-2)" "unprognostic (7.01e-2)" "unprognostic (3.08e-3)" "unprognostic (3.49e-3)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (1.07e-1)" "unprognostic (2.25e-1)" "unprognostic (1.50e-1)" "unprognostic (2.88e-3)" "unprognostic (9.85e-2)" "unprognostic (2.81e-1)" "unprognostic (1.85e-1)" "unprognostic (1.80e-1)" "unprognostic (1.58e-2)" "unprognostic (1.38e-1)" 28.1 24.6 64.6 3.5 67.2 2.9 27.0 62.1 86.8 30.4 58.3 34.3 2.8 23.6 12.5 80.1 18.9 3.6 56.8 64.4 64.6 33.8 21.8 27.1 4.3 65.6 65.3 20.0 20.5 13.1 38.2 9.0 66.9 38.3 6.9 10.2 27.3 12.3 59.0 69.9 19.5 8.9 64.2 20.6 24.2 16.5 64.8 9.2 20.5 25.2 10.2 34.5 44.2 65.4 59.0 105.6 44.2 25.6 22.2 17.5 39.6 49.9 25.1 64.5 29.5 62.4 29.7 20.4 10.9 63.2 60.7 43.7 46.0 114.1 19.3 19.5 108.4 6.6 43.7 56.1 38.5 13.9 12.0 28.3 118.0 42.0 51.5 19.6 31.5 34.3 29.7 32.3 40.9 110.6 34.0 50.5 26.5 39.9 94.5 31.6 40.7 18.2 47.0 33.2 87.6 43.7 25.5 55.4 17.9 31.5 43.3 14.8 35.4 47.3 44.7 16.4 39.7 20.3 17.7 15.4 39.1 17.0 38.3 0.0 0.5 0.6 0.8 0.7 0.4 0.3 0.9 0.8 0.7 2.0 0.9 0.3 0.0 0.1 4.0 0.9 1.5 0.2 64.6 67.2 62.1 86.8 64.4 64.6 65.6 65.3 66.9 64.2 64.8 65.4 51.3 12.8 10.7 9.1 18.0 131.2 101.7 25.4 82.0 46.0 38.8 75.7 25.2 22.8 11.2 35.0 18.8 78.8 21.5 72.2 74.3 35.2 1.6 36.1 28.6 32.0 29.3 11.2 9.8 37.4 63.4 25.9 33.6 34.1 2.5 26.8 22.9 17.4 39.9 48.8 10.6 26.5 4.1 11.7 38.4 7.9 17.1 21.3 64.0 10.3 12.8 50.8 11.3 4.0 12.3 48.2 30.9 23.0 26.5 61.2 30.8 54.6 20.0 37.6 32.9 20.3 40.3 5.4 21.4 118.1 145.9 78.1 22.0 18.8 26.2 106.4 HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452473-119637199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 320.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 225.1;Oligodendrocytes: 221.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 75.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes NA NA 450000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Peroxisomes "HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.21e-2)" "unprognostic (1.24e-2)" "unprognostic (3.12e-2)" "unprognostic (2.83e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "prognostic favorable (6.31e-6)" "unprognostic (1.60e-1)" "unprognostic (8.26e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-3)" 74.4 85.0 37.2 41.9 50.2 19.7 44.4 51.1 50.0 68.8 47.2 64.5 79.3 34.1 53.0 50.9 39.1 52.5 68.6 34.9 50.7 84.4 320.0 75.6 33.2 50.6 49.5 34.8 55.2 75.5 26.5 53.4 49.2 56.8 65.9 27.2 44.9 79.0 59.8 51.8 87.6 39.5 44.7 36.6 53.8 20.9 49.9 31.9 133.9 52.8 39.7 57.7 31.5 56.3 68.8 59.8 104.1 143.7 261.8 120.3 57.9 63.4 80.3 57.3 103.0 49.4 112.8 84.4 128.0 70.6 81.0 68.7 77.0 144.4 84.3 94.6 79.8 118.1 62.0 96.9 65.8 38.0 169.9 110.0 56.3 64.9 54.7 69.3 103.9 59.4 41.0 48.9 64.2 64.0 59.2 23.6 82.1 161.1 43.1 68.7 103.0 104.8 92.2 192.7 81.1 70.6 149.0 23.4 78.7 93.3 88.7 68.2 67.6 52.7 38.1 66.5 53.1 26.3 55.3 32.6 63.7 104.4 56.7 75.5 27.3 49.9 6.5 15.5 7.3 11.1 5.8 5.3 21.3 10.3 5.5 5.2 4.9 6.9 17.1 13.8 4.1 12.2 37.2 50.2 51.1 50.0 34.9 50.7 50.6 49.5 49.2 44.7 49.9 56.3 38.9 73.7 125.2 47.3 28.2 14.9 42.5 43.2 24.5 19.7 31.1 22.1 76.4 64.3 52.3 36.8 14.6 64.3 19.1 40.0 84.1 39.9 8.8 29.0 48.9 32.3 33.0 42.1 92.9 35.8 29.3 35.6 48.4 35.8 68.4 25.3 32.2 225.1 77.9 15.2 102.8 45.8 22.4 51.8 13.8 13.4 34.5 46.7 8.8 49.6 85.7 47.3 9.2 78.4 221.5 20.5 29.6 51.1 23.1 24.8 85.7 65.4 33.8 18.6 6.6 29.2 32.2 30.6 22.7 34.7 17.2 65.0 15.7 57.2 55.3 39.7 HSPA9 "GRP75, HSPA9B, mot-2, mthsp75, PBP74" ENSG00000113013 "Heat shock protein family A (Hsp70) member 9" P38646 5 138553756-138575675 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000898, CAB005219" Supported Supported Mitochondria NA NA 3600000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB005219: AB_647720, HPA000898: AB_1079032" "prognostic unfavorable (2.93e-4)" "unprognostic (1.86e-1)" "prognostic favorable (4.53e-4)" "unprognostic (3.73e-2)" "unprognostic (2.33e-1)" "unprognostic (9.06e-2)" "unprognostic (2.05e-2)" "unprognostic (1.10e-1)" "unprognostic (9.85e-2)" "unprognostic (2.53e-1)" "unprognostic (2.74e-1)" "unprognostic (1.31e-1)" "unprognostic (8.78e-3)" "unprognostic (1.02e-1)" "unprognostic (2.15e-1)" "unprognostic (3.27e-2)" "unprognostic (2.29e-1)" 88.6 226.3 10.3 51.5 15.1 98.8 72.4 25.4 26.0 60.3 28.8 80.3 61.2 67.0 33.9 87.8 56.5 38.3 179.5 10.9 19.6 112.1 194.2 62.5 43.6 19.6 20.7 80.0 79.8 169.4 71.4 46.5 23.8 56.4 56.5 48.8 78.9 46.7 288.9 77.5 64.3 44.2 21.6 54.7 91.8 50.1 17.8 44.6 91.3 193.6 55.7 73.8 65.6 29.1 196.0 276.6 111.4 231.0 138.1 94.3 274.7 198.3 196.7 255.4 268.6 579.4 194.4 419.3 263.7 150.8 382.0 158.6 334.0 314.1 298.2 219.7 177.9 230.5 209.0 270.4 360.4 229.0 201.3 142.6 317.7 299.5 494.8 78.7 128.0 167.8 280.4 297.5 134.7 220.6 206.7 82.9 182.5 191.6 173.3 252.1 188.8 302.4 192.8 267.4 150.1 112.4 242.5 338.5 630.7 269.0 230.5 200.5 117.7 204.1 126.5 174.9 313.5 324.6 300.5 378.6 249.6 301.4 202.6 11.8 31.3 10.7 39.8 34.9 46.2 31.7 30.6 36.8 42.0 22.4 34.1 33.9 4.3 28.3 38.8 17.9 31.3 53.6 10.3 15.1 25.4 26.0 10.9 19.6 19.6 20.7 23.8 21.6 17.8 29.1 63.0 99.3 123.8 43.1 101.7 87.8 228.6 157.2 84.8 88.2 83.4 63.8 337.3 70.1 153.8 99.3 83.4 194.7 114.7 80.8 223.0 151.4 12.1 90.1 98.4 83.1 73.0 75.1 41.1 106.1 132.9 109.6 73.9 126.6 167.8 86.1 43.5 175.9 133.9 99.3 48.4 95.4 148.5 54.1 76.4 12.6 67.4 100.1 83.6 25.3 92.3 92.5 43.3 27.6 43.3 93.8 66.0 72.6 102.3 131.1 85.8 231.3 119.7 89.3 46.0 134.3 136.2 52.5 91.4 93.2 73.9 175.5 130.7 157.9 150.7 141.2 HSPG2 "perlecan, PRCAN, SJS1" ENSG00000142798 "Heparan sulfate proteoglycan 2" P98160 1 21822244-21937310 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 366.8;Endothelial cells: 322.9;Granulosa cells: 776.0;Hepatic stellate cells: 600.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 293.0;HUVEC TERT2: 620.8;TIME: 504.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009820, HPA018892, CAB020718, HPA072690" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 1400000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB009820: AB_2119229, CAB020718: , HPA018892: AB_1850597, HPA072690: " "unprognostic (1.61e-1)" "unprognostic (1.57e-2)" "unprognostic (4.93e-2)" "unprognostic (9.60e-2)" "unprognostic (2.38e-2)" "unprognostic (8.56e-2)" "unprognostic (4.55e-1)" "unprognostic (1.90e-2)" "unprognostic (9.35e-2)" "unprognostic (2.19e-3)" "unprognostic (5.82e-2)" "unprognostic (2.83e-1)" "unprognostic (1.21e-3)" "unprognostic (1.17e-2)" "unprognostic (4.86e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (2.82e-4)" 140.7 54.7 3.8 36.1 5.2 1.7 96.2 3.7 4.8 65.9 18.8 153.1 18.3 151.9 6.6 44.1 85.0 53.4 156.6 3.6 2.9 37.6 10.6 49.0 14.2 5.6 4.6 31.3 31.7 13.1 11.8 30.3 5.7 60.3 8.6 0.3 45.0 56.5 65.1 41.0 54.9 96.2 4.0 37.4 76.1 9.0 7.6 6.7 69.1 40.8 3.5 110.2 59.7 4.7 44.0 40.7 13.8 45.9 131.0 99.4 51.5 70.2 17.8 21.1 18.7 50.5 86.7 3.3 293.0 112.9 0.8 26.9 3.1 31.9 5.4 0.6 4.3 15.7 46.0 35.7 27.0 0.0 4.1 61.6 9.4 19.9 6.0 28.1 620.8 0.3 21.4 5.7 32.4 11.8 0.0 20.0 11.7 19.6 17.9 6.3 87.8 6.1 35.1 6.5 1.3 4.1 51.4 20.0 28.7 14.0 8.1 7.2 504.3 41.1 51.8 29.7 2.3 0.5 7.3 2.6 9.7 0.1 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.8 5.2 3.7 4.8 3.6 2.9 5.6 4.6 5.7 4.0 7.6 4.7 366.8 70.5 28.6 3.6 3.9 26.4 13.5 81.1 21.1 0.6 6.2 21.5 5.8 38.6 30.3 92.0 0.0 11.0 3.4 52.9 0.0 76.1 1.4 24.2 47.7 322.9 2.4 22.9 0.8 25.0 89.0 141.3 62.2 39.8 23.4 776.0 600.4 6.6 6.8 3.3 0.8 12.6 16.2 22.1 19.2 5.8 75.2 4.6 60.5 15.9 1.8 1.6 0.0 2.5 4.3 87.5 29.9 69.2 4.6 19.3 19.2 0.9 28.7 0.6 32.9 82.5 69.8 0.3 4.8 10.0 17.8 9.3 5.0 83.3 20.1 11.8 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 HYLS1 FLJ32915 ENSG00000198331 "HYLS1 centriolar and ciliogenesis associated" Q96M11 11 125883614-125900646 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 26.5" "Cell type enhanced" "Detected in many" "Early spermatids: 80.8;Late spermatids: 54.9;Spermatocytes: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041210 Enhanced Supported "Plasma membrane,Cytosol" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA041210: AB_10794987" "unprognostic (2.46e-1)" "unprognostic (1.60e-1)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" "unprognostic (3.53e-3)" "unprognostic (1.17e-2)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.28e-1)" "unprognostic (1.04e-3)" "unprognostic (6.56e-3)" "unprognostic (7.63e-2)" "unprognostic (4.81e-3)" "unprognostic (3.00e-2)" "unprognostic (2.19e-1)" "unprognostic (2.49e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" 2.9 2.4 5.7 3.0 5.3 2.4 4.3 8.0 8.5 4.2 4.9 4.7 6.0 3.8 6.7 3.7 4.2 2.6 5.0 5.4 5.3 5.5 5.8 2.5 6.2 5.0 4.7 3.9 2.2 2.7 2.3 4.4 5.0 5.0 5.0 4.3 3.1 6.1 2.7 4.8 3.3 6.4 4.5 3.6 5.4 26.5 6.0 5.2 2.5 4.3 9.0 3.8 2.3 5.2 11.2 23.9 8.4 5.9 16.5 11.6 14.8 27.3 10.9 24.8 16.9 0.3 17.2 5.0 11.3 25.4 8.4 15.8 12.2 10.0 28.7 27.1 9.2 3.5 2.3 4.9 12.9 12.4 16.9 7.2 11.0 25.2 28.3 5.1 18.4 11.0 6.1 27.3 33.6 18.6 9.1 36.2 18.4 46.2 40.8 19.0 0.1 16.5 27.3 17.9 11.6 7.2 29.6 22.2 11.0 10.5 53.6 26.9 16.7 1.8 20.9 19.4 4.6 10.1 11.4 11.4 5.1 26.7 22.2 5.7 7.6 1.5 10.6 8.7 10.2 16.1 13.8 12.6 10.0 16.1 13.2 9.7 1.1 6.8 6.3 20.4 15.5 7.1 5.7 5.3 8.0 8.5 5.4 5.3 5.0 4.7 5.0 4.5 6.0 5.2 3.9 0.0 0.5 2.6 9.3 4.2 2.8 8.0 4.6 7.1 4.1 5.3 5.5 1.5 2.2 1.8 4.2 18.6 11.5 4.0 11.7 5.5 80.8 5.8 3.4 3.7 4.9 9.1 14.3 4.2 13.0 5.9 8.6 2.1 0.0 7.1 6.8 5.4 7.6 0.0 13.8 3.2 8.2 3.2 4.0 54.9 8.4 2.5 7.2 6.5 11.9 5.8 12.3 6.0 5.8 3.6 5.8 6.0 4.2 3.3 5.2 12.1 4.8 6.5 6.6 2.3 5.7 92.1 32.3 6.2 4.3 4.4 4.9 7.5 5.5 1.5 IARS1 "IARS, ILRS" ENSG00000196305 "Isoleucyl-tRNA synthetase 1" P41252 9 92210207-92293756 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 47.6;Cytotrophoblasts: 29.8;Extravillous trophoblasts: 31.7;Hofbauer cells: 17.2;Syncytiotrophoblasts: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029806 Approved Approved Nucleoplasm,Cytosol NA NA 100000 "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "HPA029806: AB_10601818" "unprognostic (1.32e-3)" "unprognostic (2.94e-2)" "unprognostic (2.27e-2)" "unprognostic (8.23e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (4.98e-7)" "unprognostic (2.00e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-1)" "unprognostic (4.96e-2)" "unprognostic (3.67e-2)" "unprognostic (1.40e-2)" "unprognostic (2.88e-2)" "unprognostic (4.71e-2)" "unprognostic (2.21e-1)" "unprognostic (7.76e-3)" 22.2 24.3 6.3 28.8 5.8 13.2 27.4 8.8 11.5 26.4 10.7 29.1 17.9 32.5 15.1 31.8 27.7 16.1 32.2 6.8 10.7 28.4 19.6 18.9 28.3 5.9 7.3 20.4 40.1 52.3 11.7 27.7 8.6 27.7 33.3 25.2 25.5 31.6 43.1 21.7 16.2 42.6 3.6 19.7 31.4 20.0 5.2 27.5 64.6 47.2 37.6 28.2 11.7 6.9 150.7 154.9 83.3 132.2 110.5 142.2 126.8 156.4 146.2 118.8 138.5 52.2 99.0 216.0 54.9 231.4 130.5 194.9 254.4 197.9 149.3 126.1 97.9 135.3 128.3 62.8 235.6 181.3 90.6 134.1 194.9 208.9 348.9 78.3 123.6 230.1 229.2 189.8 145.0 79.3 173.2 31.6 139.7 294.5 143.3 116.2 129.3 103.0 72.9 72.6 110.2 91.5 118.2 117.0 128.8 87.8 95.2 94.4 101.3 89.5 104.6 149.3 119.1 134.8 156.4 99.5 218.7 133.3 173.3 2.8 5.9 0.7 11.9 7.0 16.4 13.9 11.8 11.9 12.7 9.7 12.8 12.7 0.5 19.5 6.3 4.8 10.9 9.0 6.3 5.8 8.8 11.5 6.8 10.7 5.9 7.3 8.6 3.6 5.2 6.9 7.4 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.6 0.0 0.0 0.0 0.0 29.8 7.8 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 31.7 8.6 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 17.4 1.1 0.0 0.0 0.0 IARS2 FLJ10326 ENSG00000067704 "Isoleucyl-tRNA synthetase 2, mitochondrial" Q9NSE4 1 220094132-220148041 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cataract, Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024212, HPA024594, HPA024596" Enhanced Enhanced Mitochondria NA NA 35000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA024212: AB_1851363, HPA024594: AB_1851368, HPA024596: AB_1851370" "unprognostic (2.15e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.42e-3)" "unprognostic (3.22e-2)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (1.78e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.24e-5)" "unprognostic (9.48e-2)" "unprognostic (2.10e-2)" "unprognostic (3.01e-1)" "unprognostic (2.16e-1)" "unprognostic (8.87e-2)" "unprognostic (6.27e-3)" 55.8 49.8 19.9 33.3 21.1 18.3 41.8 23.5 25.4 35.3 37.8 54.2 43.4 31.8 31.4 47.9 41.4 30.5 60.0 20.0 21.8 65.5 83.8 31.0 38.8 22.7 22.2 39.0 33.6 80.5 16.0 40.7 25.0 36.1 54.8 34.8 40.0 37.5 92.9 40.5 40.4 39.4 21.6 28.4 39.1 30.1 22.3 31.8 39.7 85.7 43.1 35.6 30.0 22.9 137.2 125.6 70.7 69.9 104.2 104.4 169.6 81.4 86.9 87.9 70.7 121.7 138.8 125.6 107.1 101.4 68.0 129.3 99.0 101.5 100.9 87.5 119.3 62.6 94.6 137.8 64.6 100.4 64.9 76.0 101.3 95.4 97.6 84.7 86.9 79.9 156.9 70.7 116.7 75.9 79.8 72.0 92.1 106.2 82.1 69.5 140.7 202.2 126.2 90.4 38.0 106.6 123.2 188.2 130.3 80.6 218.5 111.9 89.8 86.1 71.6 117.0 138.4 60.0 98.9 90.8 91.3 77.3 97.6 33.8 24.6 22.8 23.0 27.7 30.8 23.6 24.9 30.3 29.2 18.3 27.8 25.6 4.7 28.3 22.3 10.6 29.9 26.7 19.9 21.1 23.5 25.4 20.0 21.8 22.7 22.2 25.0 21.6 22.3 22.9 66.4 35.3 38.0 15.7 30.7 20.1 28.6 44.1 34.7 28.6 40.1 39.4 144.3 22.8 42.9 29.5 25.0 79.0 31.5 54.2 11.7 47.7 20.0 63.8 48.3 43.7 36.2 29.6 17.3 65.4 55.5 37.0 32.1 44.3 19.6 41.3 37.5 99.6 45.9 20.2 22.7 55.4 28.5 51.0 11.2 6.8 37.3 35.9 19.6 15.0 46.1 34.6 27.8 16.6 31.5 67.4 44.9 42.5 33.1 34.1 38.4 36.1 62.0 35.5 46.0 46.3 39.0 44.6 44.1 63.5 26.6 71.7 31.0 54.4 69.9 27.6 IER3IP1 ENSG00000134049 "Immediate early response 3 interacting protein 1" Q9Y5U9 18 47152834-47176364 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Diabetes mellitus, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 357.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA010027 Supported Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "HPA010027: AB_1079098" "unprognostic (6.13e-2)" "unprognostic (2.96e-2)" "unprognostic (3.82e-2)" "unprognostic (1.45e-2)" "unprognostic (1.11e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (6.47e-6)" "unprognostic (9.86e-2)" "unprognostic (5.13e-2)" "prognostic favorable (8.59e-4)" "unprognostic (6.44e-2)" "unprognostic (6.24e-3)" "unprognostic (1.53e-3)" "unprognostic (8.55e-2)" "unprognostic (2.71e-2)" "unprognostic (8.75e-2)" "unprognostic (1.27e-3)" 13.7 17.2 8.1 11.8 8.2 14.5 14.2 11.1 10.0 10.5 11.2 14.1 16.9 11.2 10.9 12.0 9.0 10.2 17.0 8.2 9.1 31.4 19.5 12.3 11.4 8.8 8.9 11.6 13.7 19.2 15.5 10.9 9.0 13.9 13.0 14.1 15.0 7.9 31.1 13.8 15.7 9.5 8.0 11.1 15.9 9.3 8.9 11.1 15.9 21.7 10.6 13.9 11.0 8.9 27.1 15.3 22.9 20.5 30.5 33.8 15.9 62.7 30.5 30.6 32.2 12.5 22.7 26.5 19.3 28.1 25.0 32.3 21.8 22.1 33.2 43.5 19.5 23.3 23.0 38.2 32.5 70.5 33.2 26.8 27.7 27.6 20.6 28.9 26.7 23.7 19.4 39.7 33.0 15.0 25.1 33.7 11.6 11.5 18.4 24.7 35.9 37.9 31.2 26.0 26.4 29.4 21.5 18.1 38.8 16.4 18.0 40.1 38.7 45.2 23.3 22.0 34.7 56.9 66.4 27.9 35.3 44.4 37.2 15.9 17.2 16.1 25.0 16.6 22.2 18.9 21.1 21.5 16.6 20.9 19.6 20.8 1.9 17.3 17.5 34.5 23.6 19.3 8.1 8.2 11.1 10.0 8.2 9.1 8.8 8.9 9.0 8.0 8.9 8.9 80.8 86.6 51.8 7.8 58.9 0.0 64.6 0.0 73.4 48.0 96.0 51.4 63.1 97.2 19.2 51.5 8.4 104.9 61.3 35.6 140.8 124.3 18.4 49.5 47.7 70.8 37.6 51.3 15.7 138.9 126.3 76.2 57.6 55.6 13.9 40.0 83.6 138.8 108.9 40.4 17.4 69.1 0.0 63.6 0.0 13.3 84.8 54.8 0.0 12.2 79.4 69.6 86.5 16.1 19.1 139.3 50.1 48.5 158.8 117.3 125.0 357.0 26.2 48.0 52.6 40.4 61.6 163.3 158.9 88.1 0.0 177.2 54.4 36.7 62.2 109.4 IFIH1 "Hlcd, IDDM19, MDA-5, MDA5" ENSG00000115267 "Interferon induced with helicase C domain 1" Q9BYX4 2 162267074-162318684 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Aicardi-Goutieres syndrome, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.1" "Cell type enhanced" "Detected in many" "Early spermatids: 55.6;Late spermatids: 53.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 62.3;BJ hTERT+ SV40 Large T+ RasG12V: 71.5;Karpas-707: 38.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002656 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA002656: AB_1079344" "unprognostic (2.85e-1)" "unprognostic (4.71e-2)" "unprognostic (5.51e-2)" "unprognostic (3.85e-3)" "unprognostic (3.34e-1)" "unprognostic (1.39e-1)" "unprognostic (5.65e-2)" "unprognostic (5.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.86e-2)" "unprognostic (1.53e-2)" "unprognostic (2.62e-1)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.41e-2)" "unprognostic (7.29e-2)" 6.2 6.4 3.1 12.7 4.3 38.1 5.9 3.2 3.0 6.5 4.4 7.4 13.1 6.4 4.3 7.5 7.2 9.5 5.1 2.3 3.3 5.6 8.5 10.9 11.7 7.2 3.4 7.0 7.1 8.1 5.9 8.3 5.0 5.5 6.8 1.1 17.5 4.7 1.7 5.0 10.0 5.7 8.1 16.4 9.6 2.4 4.2 10.9 6.0 3.2 9.7 6.4 5.2 4.4 6.7 0.3 0.2 0.0 7.4 6.0 2.8 1.2 17.7 62.3 71.5 1.2 16.7 13.3 10.5 1.0 31.9 8.5 1.1 9.8 6.3 35.4 4.5 7.1 0.8 2.8 5.0 8.2 6.4 5.3 4.8 8.9 1.7 6.5 4.9 6.9 0.3 38.9 1.0 12.5 9.3 6.4 0.0 5.4 3.8 7.5 0.0 18.8 5.9 7.3 0.4 0.1 3.7 20.7 34.0 0.3 5.7 7.1 4.1 1.9 1.7 1.1 2.7 15.2 26.8 1.9 3.5 6.5 5.6 4.4 11.5 4.4 6.6 12.5 9.2 12.4 8.2 7.2 11.1 12.8 6.7 6.9 15.2 4.0 12.7 1.6 10.3 7.8 3.1 4.3 3.2 3.0 2.3 3.3 7.2 3.4 5.0 8.1 4.2 4.4 24.7 32.1 12.0 4.6 20.1 6.8 11.2 7.7 6.2 0.0 4.8 5.2 5.0 12.8 11.1 7.3 0.0 6.4 10.2 10.9 5.9 18.7 55.6 17.3 7.9 22.3 15.7 8.2 2.8 18.7 17.5 8.8 10.7 20.2 13.3 10.4 13.6 6.5 14.4 0.0 0.7 11.5 8.2 12.8 8.7 53.3 13.7 20.0 5.4 28.1 23.9 7.3 10.3 0.5 4.0 13.4 10.1 13.2 16.0 9.1 11.8 4.8 17.5 0.1 0.0 10.9 4.9 1.6 1.3 10.2 5.8 3.4 13.1 6.9 6.7 11.1 IFITM5 "BRIL, DSPA1, fragilis4, Hrmp1" ENSG00000206013 "Interferon induced transmembrane protein 5" A6NNB3 11 298200-299526 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Mineral balance" "Developmental protein" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 4.9;pancreas: 7.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 8 "cerebral cortex: 4.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039258 Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Cytosol" "HPA039258: AB_10673608" "unprognostic (9.84e-2)" "unprognostic (2.15e-1)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (7.46e-2)" "unprognostic (4.20e-2)" "unprognostic (4.42e-2)" "unprognostic (8.31e-2)" "unprognostic (7.99e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (4.90e-2)" 0.1 0.0 0.0 0.1 0.0 0.7 0.2 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.1 0.1 0.1 0.0 7.3 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFT122 "FAP80, SPG, WDR10, WDR10p, WDR140" ENSG00000163913 "Intraflagellar transport 122" Q9HBG6 3 129440036-129520507 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 72.8" "Cell type enhanced" "Detected in many" "Early spermatids: 81.7;Late spermatids: 70.3;Spermatocytes: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041815 Uncertain Uncertain Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA041815: AB_10804118" "unprognostic (7.16e-2)" "unprognostic (3.71e-3)" "unprognostic (3.67e-1)" "unprognostic (7.61e-3)" "unprognostic (5.29e-2)" "unprognostic (5.33e-3)" "unprognostic (4.68e-2)" "unprognostic (1.82e-1)" "unprognostic (7.90e-2)" "unprognostic (3.30e-1)" "unprognostic (1.67e-2)" "unprognostic (3.50e-2)" "unprognostic (1.09e-2)" "unprognostic (7.67e-2)" "unprognostic (5.33e-1)" "unprognostic (9.91e-2)" "unprognostic (4.20e-3)" 9.6 7.4 5.7 5.2 7.6 10.1 12.4 6.5 9.2 13.1 15.3 7.6 4.7 12.6 12.7 7.2 24.7 6.7 12.0 6.8 6.8 11.7 9.2 8.8 6.7 4.5 6.2 25.4 13.3 13.9 14.4 10.8 3.0 7.4 6.9 11.2 7.9 8.5 3.9 13.8 5.3 8.9 3.7 4.5 9.0 72.8 7.0 8.9 13.1 2.9 5.7 6.6 8.4 6.3 16.5 24.6 21.0 13.5 29.7 21.0 10.5 8.5 12.9 14.8 14.1 11.9 10.7 10.6 10.0 11.3 14.5 10.4 8.2 7.7 13.3 5.8 8.8 8.2 21.8 10.3 8.1 22.2 7.2 24.7 5.7 11.4 8.8 12.9 20.3 21.8 8.4 22.1 12.1 18.2 18.2 11.6 14.1 12.3 7.0 16.3 8.0 7.7 15.7 3.0 25.9 10.6 24.8 8.2 7.5 7.9 22.6 17.9 9.0 10.1 8.7 13.6 10.2 15.0 11.4 9.3 9.2 11.3 8.1 4.5 3.1 3.7 0.9 2.2 1.6 1.9 1.6 2.3 3.2 2.1 1.8 2.2 1.4 1.5 0.9 0.8 3.0 2.1 5.7 7.6 6.5 9.2 6.8 6.8 4.5 6.2 3.0 3.7 7.0 6.3 7.5 9.6 8.2 28.1 4.3 2.7 5.8 4.5 2.8 9.7 18.0 13.3 6.4 15.7 5.6 25.8 37.5 6.7 4.5 6.2 7.9 5.2 81.7 43.4 11.0 9.7 3.0 7.4 35.1 8.9 5.2 9.8 19.9 10.2 5.1 8.7 20.7 6.0 9.3 5.0 23.1 10.2 4.1 7.2 2.2 70.3 18.6 4.1 3.6 15.0 3.8 11.8 3.1 12.1 15.9 3.4 4.2 13.9 3.4 3.6 6.2 8.2 37.3 21.4 0.0 12.8 7.7 120.4 38.0 5.4 2.8 2.6 4.1 10.6 8.7 3.4 IFT140 "gs114, KIAA0590, WDTC2" ENSG00000187535 "Intraflagellar transport 140" Q96RY7 16 1510427-1612072 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 27.8;Late spermatids: 25.6;Respiratory ciliated cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042197 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "HPA042197: AB_2677895" "unprognostic (1.53e-1)" "unprognostic (1.53e-1)" "unprognostic (1.30e-1)" "unprognostic (5.21e-3)" "unprognostic (2.27e-1)" "unprognostic (2.87e-2)" "unprognostic (5.27e-3)" "unprognostic (3.28e-2)" "unprognostic (2.63e-1)" "unprognostic (4.35e-3)" "unprognostic (1.08e-1)" "unprognostic (1.52e-1)" "unprognostic (2.77e-2)" "unprognostic (7.55e-2)" "unprognostic (8.95e-2)" "unprognostic (2.91e-3)" "unprognostic (6.22e-3)" 5.5 8.9 10.1 2.2 10.3 1.8 7.0 10.5 13.2 11.3 20.8 7.4 3.4 9.6 4.9 4.1 15.3 5.3 4.9 9.8 11.8 10.4 3.8 8.7 2.4 10.2 14.8 12.6 7.7 8.4 15.7 3.1 9.8 9.5 1.3 6.4 6.0 5.3 2.7 5.6 4.8 2.5 10.2 4.1 6.8 15.3 11.6 3.2 22.9 1.0 1.1 12.0 7.2 8.3 2.0 12.4 9.5 9.6 8.0 5.9 5.4 2.6 9.5 2.7 3.3 3.4 9.9 3.8 7.3 3.9 3.6 7.5 1.7 1.5 1.9 3.3 7.6 2.3 9.3 8.3 6.9 1.3 4.7 8.4 5.9 3.2 4.2 10.5 2.0 7.6 2.6 2.2 2.1 12.0 6.9 3.9 10.4 2.5 2.9 6.3 3.4 5.7 8.3 6.2 18.0 10.0 2.9 5.0 3.9 5.1 17.4 5.1 3.9 2.2 7.0 4.0 1.1 6.8 2.6 2.4 3.7 0.8 2.9 0.0 0.4 0.2 0.4 0.2 3.7 0.6 0.6 1.4 0.6 0.2 1.9 3.0 0.0 1.1 0.3 0.5 0.1 0.8 10.1 10.3 10.5 13.2 9.8 11.8 10.2 14.8 9.8 10.2 11.6 8.3 2.9 12.8 11.5 19.9 1.2 1.7 2.9 4.0 4.6 3.7 6.8 6.0 4.0 5.7 6.1 11.0 25.0 7.8 2.2 2.1 1.9 3.2 21.7 27.8 5.9 2.1 5.4 2.5 12.7 1.0 1.3 4.5 7.1 6.2 1.3 11.5 2.2 0.9 2.3 8.4 12.4 6.1 8.2 0.6 0.7 25.6 4.7 1.4 0.0 13.1 0.4 5.6 0.0 6.6 4.9 2.1 1.5 4.1 0.7 1.4 1.0 3.5 31.2 17.2 0.0 3.1 3.0 20.9 7.5 2.0 1.1 2.2 1.6 6.2 3.5 1.5 IFT172 "BBS20, NPHP17, osm-1, SLB, wim" ENSG00000138002 "Intraflagellar transport 172" Q9UG01 2 27444377-27489805 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 439.9;Late spermatids: 703.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044893 Uncertain NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 34: Spermatids - Unknown function" "HPA044893: AB_10795009" "unprognostic (1.05e-3)" "unprognostic (6.52e-2)" "unprognostic (7.04e-2)" "unprognostic (3.57e-3)" "unprognostic (1.95e-1)" "unprognostic (1.29e-2)" "prognostic unfavorable (6.05e-6)" "unprognostic (6.86e-3)" "unprognostic (1.45e-1)" "unprognostic (8.49e-2)" "unprognostic (1.08e-1)" "unprognostic (1.51e-2)" "unprognostic (4.32e-2)" "unprognostic (9.52e-2)" "unprognostic (5.49e-2)" "unprognostic (1.19e-1)" "unprognostic (5.47e-2)" 3.1 3.3 2.2 2.5 2.6 1.8 4.0 2.5 2.4 5.2 11.8 4.6 1.8 4.5 1.6 2.4 17.0 3.2 4.3 2.3 2.8 4.5 1.5 4.9 2.0 3.6 3.6 8.9 4.8 13.0 9.9 2.4 3.5 3.6 2.1 5.7 4.2 4.2 3.6 2.9 2.7 3.8 2.4 3.9 3.5 12.5 2.4 2.7 5.9 3.9 2.1 3.6 3.4 3.7 5.8 5.3 7.1 10.0 12.6 10.6 4.5 5.5 4.0 6.5 5.5 4.8 4.6 6.3 8.3 7.3 3.9 6.4 13.4 6.7 6.2 3.1 9.4 16.1 9.4 5.6 7.3 7.8 3.4 8.6 3.0 10.3 3.8 9.0 10.8 7.3 5.3 2.2 2.4 4.5 4.4 3.8 5.0 4.6 5.5 0.0 3.7 3.5 5.0 3.7 5.5 8.8 2.8 4.8 9.7 6.0 4.8 4.6 11.6 2.9 1.7 3.7 8.3 2.8 1.7 6.7 11.9 2.3 5.7 0.0 0.4 0.3 0.4 0.6 0.3 0.7 0.2 0.4 0.9 0.5 0.3 0.3 0.0 0.9 0.1 0.4 0.2 0.4 2.2 2.6 2.5 2.4 2.3 2.8 3.6 3.6 3.5 2.4 2.4 3.7 5.2 3.2 9.4 53.5 3.1 2.0 16.6 35.3 8.6 15.4 17.2 12.1 6.3 38.6 32.7 23.9 52.1 1.0 1.7 82.4 0.0 34.4 439.9 59.0 7.1 4.5 34.7 7.6 63.2 98.7 0.6 5.9 23.9 14.2 0.0 11.0 5.7 1.2 1.7 5.0 64.3 96.4 57.0 3.2 1.6 703.6 12.8 2.8 5.4 11.2 1.9 7.1 5.2 24.6 44.9 104.9 106.3 10.9 2.4 7.5 142.0 2.3 154.6 41.7 0.0 11.7 8.5 22.6 6.6 10.1 1.4 0.4 2.8 10.1 75.1 39.8 IFT43 "C14orf179, FLJ32173, MGC16028" ENSG00000119650 "Intraflagellar transport 43" Q96FT9 14 75902136-76084585 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 305.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003438 Approved Supported "Microtubules,Centriolar satellite" NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Microtubules "Centriolar satellite" "HPA003438: AB_1078327" "unprognostic (1.64e-2)" "unprognostic (5.75e-3)" "unprognostic (2.10e-1)" "unprognostic (1.81e-3)" "unprognostic (1.48e-1)" "unprognostic (8.73e-2)" "unprognostic (1.53e-2)" "unprognostic (5.27e-2)" "unprognostic (8.87e-2)" "unprognostic (1.26e-2)" "unprognostic (2.32e-2)" "unprognostic (9.78e-2)" "unprognostic (4.43e-2)" "unprognostic (2.51e-1)" "unprognostic (2.70e-2)" "unprognostic (1.75e-1)" "unprognostic (1.07e-2)" 21.5 24.0 29.2 12.2 29.5 5.4 25.1 28.9 31.4 24.6 38.7 27.5 23.0 24.6 49.6 18.0 64.5 18.2 43.2 28.7 29.7 38.9 41.5 20.6 11.6 29.5 31.2 16.2 22.6 27.1 32.8 21.5 30.9 26.9 19.4 25.1 16.1 30.5 13.9 15.4 19.3 27.7 29.8 15.5 21.6 40.5 29.4 15.9 33.0 8.8 17.0 25.5 18.4 29.8 34.8 38.2 27.5 42.7 33.9 54.3 19.5 22.3 42.7 33.6 33.5 14.6 34.9 3.9 23.8 39.5 30.4 36.2 26.7 41.3 37.6 18.3 25.6 1.8 22.3 0.1 94.9 3.8 8.0 48.6 44.4 37.1 48.3 48.6 52.1 38.5 9.6 15.2 40.8 69.7 14.3 6.0 14.2 42.7 48.9 9.1 22.2 10.9 77.0 30.0 26.7 31.9 43.9 29.8 31.5 36.9 77.4 10.2 24.3 19.7 24.7 28.9 19.6 20.1 18.8 4.4 76.9 1.6 20.6 34.5 11.6 19.7 13.8 16.4 17.6 33.8 14.9 14.4 15.7 23.1 24.3 23.4 5.8 15.4 16.4 20.2 19.6 13.4 29.2 29.5 28.9 31.4 28.7 29.7 29.5 31.2 30.9 29.8 29.4 29.8 40.9 12.8 27.4 50.3 14.8 18.6 44.1 103.7 38.1 27.8 36.0 45.6 43.8 42.9 66.1 64.4 66.7 41.9 8.7 24.7 64.6 53.8 147.5 171.0 54.5 35.3 15.7 5.9 46.4 38.7 14.7 39.4 38.2 33.2 26.6 28.7 38.6 32.9 22.4 10.1 55.0 30.2 61.1 7.6 20.0 33.2 33.8 11.5 26.6 14.0 32.0 49.8 14.4 38.2 38.5 33.5 18.7 35.0 13.7 25.8 45.1 160.2 305.8 87.7 32.9 31.2 63.5 124.4 37.2 24.6 21.6 41.9 16.2 32.8 26.1 34.5 IFT52 "C20orf9, CGI-53, dJ1028D15.1, NGD2, NGD5" ENSG00000101052 "Intraflagellar transport 52" Q9Y366 20 43590937-43647299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 78.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063367, HPA067423" Enhanced Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "HPA063367: , HPA067423: AB_2685837" "unprognostic (2.88e-1)" "unprognostic (2.44e-2)" "unprognostic (6.82e-2)" "unprognostic (5.18e-3)" "unprognostic (7.39e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.30e-6)" "unprognostic (8.36e-2)" "unprognostic (1.25e-1)" "unprognostic (2.00e-1)" "unprognostic (2.98e-2)" "unprognostic (2.28e-2)" "unprognostic (3.43e-2)" "unprognostic (7.51e-2)" "prognostic favorable (3.33e-4)" "unprognostic (2.37e-1)" "unprognostic (7.40e-2)" 23.5 15.1 12.2 11.7 12.6 29.1 26.1 12.4 15.2 29.3 14.3 16.3 9.2 27.4 29.0 14.8 38.0 19.0 11.8 12.5 13.5 20.5 7.8 16.9 18.3 12.3 12.8 39.2 15.7 22.5 16.5 17.5 12.8 17.5 17.8 15.1 13.6 23.8 4.7 15.5 11.2 24.3 13.3 15.7 12.2 31.8 14.1 22.8 31.3 9.0 18.9 19.5 18.0 14.2 33.9 25.4 50.3 35.8 41.9 46.4 23.9 20.8 46.1 53.6 51.6 70.5 33.7 18.8 32.8 42.6 43.4 27.7 21.3 37.3 58.6 15.6 20.0 24.8 16.2 65.9 51.4 33.4 16.4 37.8 40.2 34.9 27.0 39.0 42.7 41.4 21.3 26.1 39.9 34.0 46.4 51.5 28.4 22.2 24.9 48.6 57.5 27.8 41.8 32.9 38.8 45.3 63.6 46.7 52.2 25.3 21.8 45.1 26.9 47.3 35.1 26.3 31.1 25.3 26.9 32.8 56.8 24.0 34.8 8.0 22.0 16.8 18.4 20.9 15.0 17.5 14.7 17.5 28.4 15.3 15.4 16.0 6.3 17.4 26.2 21.5 18.6 17.3 12.2 12.6 12.4 15.2 12.5 13.5 12.3 12.8 12.8 13.3 14.1 14.2 21.1 6.4 13.1 11.4 13.7 13.0 12.8 22.4 12.0 11.5 14.1 19.2 2.9 11.5 13.2 7.3 0.0 19.9 16.0 14.8 19.6 26.1 78.4 32.1 19.4 18.1 9.5 23.4 20.5 22.2 19.7 25.3 8.2 10.5 14.5 26.7 23.2 2.6 19.4 8.4 22.5 11.0 14.2 18.2 13.9 20.9 28.6 13.3 17.8 12.2 21.3 22.6 18.6 14.6 25.7 14.8 10.1 38.4 13.5 5.9 5.5 18.3 49.0 12.8 13.1 23.9 24.8 57.3 18.5 12.2 14.9 9.6 12.1 30.4 10.3 10.5 IFT57 "ESRRBL1, FLJ10147, HIPPI, MHS4R2" ENSG00000114446 "Intraflagellar transport 57" Q9NWB7 3 108160812-108222435 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" DNA-binding Ciliopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 1675.3;Late spermatids: 2795.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 41.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035514, HPA035515" Supported Approved "Nuclear speckles,Mitochondria,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 34: Spermatids - Unknown function" "Nuclear speckles" "Mitochondria, Cytosol" "HPA035514: AB_10601757, HPA035515: AB_10696505" "unprognostic (1.35e-2)" "unprognostic (1.37e-2)" "prognostic favorable (6.96e-5)" "unprognostic (2.98e-2)" "unprognostic (5.46e-3)" "unprognostic (1.02e-2)" "unprognostic (3.79e-2)" "unprognostic (3.61e-3)" "unprognostic (3.59e-2)" "prognostic favorable (7.63e-4)" "unprognostic (5.04e-2)" "unprognostic (2.78e-1)" "unprognostic (1.68e-3)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (8.67e-3)" "unprognostic (6.12e-2)" 8.9 15.3 11.6 8.6 11.7 13.2 13.1 10.2 15.5 11.7 14.8 13.3 6.0 13.3 45.1 8.5 32.0 13.4 10.4 11.4 11.5 21.3 4.5 40.7 17.3 12.0 12.2 14.0 13.8 23.0 16.3 7.8 11.6 27.5 14.6 24.0 9.1 17.5 4.2 8.6 9.0 10.6 11.9 12.1 9.8 42.8 12.0 8.2 26.1 4.4 16.4 13.9 8.3 11.8 35.5 17.2 12.8 23.1 26.1 26.9 7.1 10.6 25.8 15.3 13.6 12.4 6.1 39.5 13.3 17.8 22.0 13.9 11.5 17.8 25.8 6.2 12.2 13.6 8.0 3.3 19.4 28.5 30.2 16.3 16.1 19.9 34.2 24.4 17.5 6.6 6.4 6.9 17.8 18.9 9.5 25.8 13.6 2.7 21.0 6.1 11.5 6.3 31.6 12.3 21.1 14.7 15.9 5.2 9.9 7.1 11.0 8.3 7.5 19.6 10.2 10.5 12.6 8.1 6.2 20.7 28.4 2.7 7.3 0.2 3.5 3.1 3.6 6.5 5.8 41.9 7.4 4.5 10.2 34.9 6.2 3.7 1.8 6.8 12.8 2.0 5.1 4.9 11.6 11.7 10.2 15.5 11.4 11.5 12.0 12.2 11.6 11.9 12.0 11.8 36.6 471.1 291.2 18.6 98.4 41.0 114.1 72.9 34.7 25.6 42.2 50.9 33.8 58.6 201.9 51.5 68.8 22.3 16.9 51.1 117.4 158.8 1675.3 266.3 57.8 38.2 57.2 13.7 52.6 134.1 19.3 78.9 25.5 37.0 44.3 57.1 25.7 5.9 14.5 28.6 20.3 35.7 42.7 8.1 27.7 2795.4 65.3 19.3 46.2 4.7 13.1 56.8 8.2 13.0 13.5 79.4 36.6 64.3 40.2 151.4 24.3 124.5 528.7 72.7 52.6 61.7 61.3 242.2 43.6 25.4 37.2 14.9 30.2 104.9 52.3 93.0 IFT80 "FAP167, KIAA1374, WDR56" ENSG00000068885 "Intraflagellar transport 80" Q9P2H3 3 160256986-160399880 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 254.5;Respiratory ciliated cells: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035868 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA035868: AB_10959463" "unprognostic (2.71e-2)" "unprognostic (4.47e-3)" "unprognostic (2.13e-1)" "unprognostic (5.29e-2)" "unprognostic (3.03e-1)" "unprognostic (7.25e-2)" "unprognostic (4.08e-3)" "unprognostic (1.29e-2)" "unprognostic (5.95e-2)" "unprognostic (6.70e-2)" "unprognostic (8.31e-2)" "unprognostic (4.24e-3)" "unprognostic (4.52e-2)" "unprognostic (4.32e-2)" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (5.60e-3)" 7.5 10.0 17.2 8.3 25.6 6.2 11.5 17.0 26.2 13.3 20.6 7.7 6.1 14.6 16.9 8.9 17.3 11.6 10.0 17.6 20.0 17.9 7.6 14.5 12.1 18.7 21.0 16.5 10.2 27.5 25.7 7.6 18.7 9.8 9.9 25.1 7.3 10.8 4.7 12.3 8.3 10.8 15.4 9.4 11.2 24.1 19.7 18.2 18.2 6.8 11.6 8.9 8.9 40.1 23.9 16.3 36.9 16.9 34.0 59.8 9.1 20.0 29.3 15.1 19.8 13.3 33.9 15.5 25.7 18.9 22.9 20.3 13.1 19.3 33.7 23.1 14.5 20.7 23.4 9.5 33.8 9.9 17.4 33.2 13.0 17.2 18.4 68.1 17.1 19.7 8.9 28.8 23.8 11.5 18.4 11.7 11.6 15.0 9.5 16.3 19.3 26.3 31.5 6.9 22.0 23.2 21.9 20.6 26.1 23.9 34.5 11.3 15.3 15.5 10.5 21.2 19.9 41.7 28.9 28.5 26.7 17.8 15.6 0.9 0.5 0.5 0.6 0.2 0.6 0.8 0.7 0.7 0.7 0.7 1.0 0.7 0.4 0.9 0.5 1.4 1.0 0.6 17.2 25.6 17.0 26.2 17.6 20.0 18.7 21.0 18.7 15.4 19.7 40.1 6.5 41.7 33.0 42.7 7.0 3.3 5.9 7.5 15.4 16.7 6.4 3.8 7.2 18.6 14.4 23.9 16.7 3.1 7.3 3.8 7.9 5.6 30.5 39.0 19.0 7.0 11.4 11.6 61.7 1.8 2.9 13.8 5.6 9.6 2.5 13.3 6.8 4.0 2.9 1.7 44.9 5.2 2.0 4.1 2.7 9.5 16.4 4.4 1.8 27.2 2.5 8.0 7.2 46.3 254.5 2.6 2.6 21.8 10.9 2.4 1.9 6.7 71.7 18.1 6.6 8.3 8.3 43.2 10.4 8.5 3.8 0.7 8.8 11.6 5.1 3.6 IFT81 "CDV-1R, CDV1, MGC4027" ENSG00000122970 "Intraflagellar transport 81" Q8WYA0 12 110124335-110218793 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 79.1;Respiratory ciliated cells: 148.2;Spermatocytes: 179.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019087, HPA020051" Enhanced Approved Centrosome,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Cytosol Centrosome "HPA019087: AB_1851462, HPA020051: AB_1851465" "unprognostic (2.54e-1)" "unprognostic (1.47e-1)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (1.39e-1)" "unprognostic (9.79e-2)" "unprognostic (1.10e-1)" "unprognostic (7.95e-2)" "unprognostic (3.91e-1)" "unprognostic (3.21e-1)" "unprognostic (1.40e-2)" "unprognostic (1.04e-2)" "unprognostic (2.24e-3)" "unprognostic (1.85e-2)" "unprognostic (4.23e-2)" "unprognostic (1.88e-1)" "unprognostic (2.45e-1)" 5.9 9.0 5.0 4.6 5.0 1.5 8.8 7.5 6.0 15.6 10.8 13.6 2.7 14.5 18.5 5.9 18.3 8.5 7.6 5.2 6.0 9.4 4.1 8.3 3.0 7.2 7.0 14.5 5.2 16.5 15.2 5.0 4.4 12.3 5.7 23.0 9.3 14.3 6.8 5.7 5.2 8.5 5.1 4.0 7.4 31.8 5.3 5.8 13.8 6.7 2.9 11.5 9.7 4.1 14.1 26.2 53.0 22.7 9.6 19.6 4.0 8.8 13.5 18.7 16.0 5.1 7.8 4.6 4.8 17.0 13.2 12.2 19.7 10.4 24.1 5.9 10.8 9.7 15.4 8.4 8.3 6.0 4.5 14.1 11.6 17.7 4.5 45.2 11.8 9.0 12.0 2.5 17.3 3.0 12.3 10.1 26.2 8.1 8.6 14.4 13.9 6.2 23.2 9.4 32.8 36.2 24.1 5.0 36.8 14.7 26.9 9.1 8.0 10.5 5.4 8.8 8.4 7.9 8.0 6.3 25.3 7.6 12.2 0.0 0.3 0.1 0.2 0.2 0.5 0.4 0.5 0.2 1.0 0.4 0.4 0.1 0.8 0.7 0.3 1.0 0.2 0.3 5.0 5.0 7.5 6.0 5.2 6.0 7.2 7.0 4.4 5.1 5.3 4.1 5.2 12.8 20.1 26.4 2.4 6.1 12.9 20.3 11.4 16.4 8.6 11.6 22.1 8.6 26.0 14.7 41.7 2.5 0.6 2.3 15.6 10.9 51.8 79.1 36.1 6.0 21.6 2.5 30.1 4.0 1.6 14.9 8.2 11.9 3.8 16.8 4.6 4.8 2.6 25.2 31.8 4.3 18.3 1.3 1.4 18.1 14.0 2.5 35.6 11.2 2.1 19.1 1.0 41.2 14.5 5.7 1.9 27.8 1.9 3.6 0.9 10.5 148.2 37.7 6.6 14.4 25.6 179.0 46.0 7.4 6.5 1.0 1.5 36.3 3.5 4.8 IGBP1 "α4, IBP1" ENSG00000089289 "Immunoglobulin binding protein 1" P78318 X 70133447-70166324 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" Chaperone "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 342.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000634, HPA001004, CAB034139" Approved Approved Cytosol NA NA 48000 "Cluster 44: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 32: Non-specific - Translation" Cytosol "CAB034139: AB_2295670, HPA000634: AB_1079102, HPA001004: AB_1079104" "unprognostic (3.59e-2)" "unprognostic (5.35e-2)" "unprognostic (2.05e-1)" "unprognostic (5.35e-3)" "unprognostic (1.22e-2)" "unprognostic (1.11e-2)" "unprognostic (4.84e-3)" "unprognostic (2.21e-2)" "unprognostic (1.50e-1)" "unprognostic (2.22e-1)" "unprognostic (1.74e-1)" "unprognostic (3.00e-1)" "unprognostic (2.67e-2)" "unprognostic (1.46e-1)" "unprognostic (5.86e-2)" "unprognostic (1.42e-2)" "unprognostic (4.10e-3)" 56.3 43.2 38.5 29.7 40.3 57.5 55.1 40.3 45.8 68.6 36.9 60.2 57.8 53.3 62.0 46.6 73.5 48.3 53.4 38.6 40.4 57.9 29.4 36.6 59.4 40.4 39.9 119.1 118.6 38.7 35.6 37.6 40.6 42.2 56.2 30.1 64.4 32.1 118.0 63.4 58.3 42.4 41.7 40.7 70.1 18.7 39.7 68.2 57.3 99.9 69.5 52.4 54.5 42.7 42.7 48.9 30.9 35.9 122.2 163.3 44.5 35.6 99.6 47.9 57.1 45.5 55.7 79.1 58.7 62.0 62.6 57.1 73.8 59.1 60.8 31.4 53.2 25.1 52.7 82.9 83.6 59.4 43.9 158.1 143.1 44.3 63.2 166.6 81.8 57.9 51.4 69.5 52.6 42.7 48.7 100.4 37.5 98.0 73.6 42.3 65.0 79.5 77.8 67.2 35.4 43.4 46.3 40.0 87.0 56.4 21.3 61.1 65.8 25.8 40.2 46.0 27.2 65.0 53.7 40.1 36.4 50.5 31.1 51.4 46.1 41.8 34.1 46.0 40.9 50.9 47.4 45.2 51.1 41.8 53.7 48.9 31.4 39.8 39.0 25.6 75.2 48.0 38.5 40.3 40.3 45.8 38.6 40.4 40.4 39.9 40.6 41.7 39.7 42.7 50.1 32.1 54.7 12.1 79.3 100.1 114.2 163.9 82.0 21.5 81.4 82.2 75.8 70.1 85.6 27.6 8.4 123.8 45.3 91.3 103.7 80.3 126.3 58.0 61.1 64.1 69.9 38.9 19.3 143.2 129.0 62.2 46.9 57.9 34.8 90.8 85.3 20.9 82.7 6.7 19.5 128.0 69.2 123.1 89.6 121.5 81.4 75.6 49.8 15.0 119.8 48.9 90.6 13.6 27.6 86.4 153.1 61.7 52.9 70.8 342.0 182.0 57.8 23.6 26.3 62.3 63.0 12.2 25.0 76.2 120.3 124.9 81.9 96.1 128.4 130.4 IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2141238 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 2749.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1104.3;Extravillous trophoblasts: 3196.3;Leydig cells: 3007.5;Peritubular cells: 643.9;Syncytiotrophoblasts: 1612.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 86.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 862.0;Hep G2: 600.5;LHCN-M2: 333.7;RH-30: 408.5;SH-SY5Y: 495.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007556, HPA007993" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 609000000 1200000000 "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "HPA007556: AB_2667860, HPA007993: AB_1851474" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (2.30e-3)" "unprognostic (2.59e-1)" "prognostic favorable (7.12e-4)" "unprognostic (7.92e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.98e-2)" "unprognostic (8.93e-3)" "unprognostic (5.78e-2)" 99.7 58.4 5.5 9.2 32.6 0.9 41.8 12.6 86.0 75.5 236.8 22.3 4.7 75.2 52.7 18.8 128.4 34.8 91.7 6.5 7.1 31.8 305.9 9.8 3.4 20.2 6.6 117.8 37.5 5.2 25.4 2749.2 10.1 14.5 4.8 0.5 11.6 15.2 82.1 8.4 10.9 14.7 13.0 14.4 11.9 23.7 10.9 3.4 12.4 114.0 4.7 24.2 23.6 9.0 0.0 2.8 0.3 0.6 0.2 0.3 1.8 112.8 1.3 3.6 0.4 862.0 0.4 0.1 8.4 0.0 2.1 0.1 0.9 7.0 7.9 0.1 0.5 0.2 0.2 600.5 143.4 0.7 0.0 174.7 0.5 0.7 0.2 0.1 1.4 0.0 0.3 0.0 333.7 2.2 0.1 0.8 1.2 0.2 1.5 0.1 408.5 0.9 0.0 0.9 32.7 495.6 0.7 0.1 0.0 83.0 4.2 0.0 0.4 0.2 20.1 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 32.6 12.6 86.0 6.5 7.1 20.2 6.6 10.1 13.0 10.9 9.0 40.6 3.2 3.1 0.0 2.6 5.4 0.5 0.5 0.6 0.4 0.0 0.0 6.5 8.6 0.9 3.7 0.0 1104.3 0.0 0.0 0.0 0.0 13.1 0.0 0.0 498.4 0.0 16.0 0.0 0.0 3196.3 334.2 0.0 0.0 0.0 0.0 171.4 494.9 218.2 0.0 0.0 0.0 0.0 11.6 5.5 91.1 3007.5 3.4 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 643.9 0.0 1.1 0.0 0.0 0.9 0.5 65.7 33.5 37.5 3.8 6.3 1.5 4.1 1612.9 1.8 0.0 0.0 0.4 IGSF3 "EWI-3, MGC117164, V8" ENSG00000143061 "Immunoglobulin superfamily member 3" O75054 1 116574399-116667755 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 256.5;WM-115: 239.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036305, HPA036306" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA036305: AB_2675050, HPA036306: AB_10671245" "unprognostic (9.87e-2)" "unprognostic (3.64e-1)" "unprognostic (9.51e-2)" "prognostic unfavorable (1.98e-4)" "unprognostic (2.97e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (4.03e-6)" "unprognostic (9.40e-2)" "unprognostic (4.41e-1)" "unprognostic (2.42e-1)" "prognostic unfavorable (2.03e-4)" "unprognostic (4.18e-1)" "prognostic favorable (2.87e-6)" "unprognostic (5.29e-2)" "unprognostic (4.23e-2)" "unprognostic (2.57e-1)" "unprognostic (1.08e-1)" 1.5 1.8 0.9 1.3 1.8 0.3 8.5 1.8 3.9 6.1 1.4 6.5 7.7 2.9 5.7 23.2 2.0 3.2 9.1 1.1 3.0 11.4 0.5 8.4 0.5 2.0 3.5 0.4 2.6 2.1 2.4 11.1 2.3 5.6 5.8 7.5 9.1 5.7 1.6 18.2 8.8 2.9 4.7 0.4 8.7 4.1 4.9 10.9 8.3 1.5 5.3 5.0 10.9 2.9 22.3 36.9 28.2 7.2 6.4 13.4 75.5 0.1 1.0 2.9 1.0 21.5 12.4 0.0 11.4 0.3 15.8 60.7 12.6 30.4 1.3 256.5 9.3 12.1 13.7 0.6 0.0 1.2 22.2 1.7 23.1 0.2 5.2 5.3 0.2 4.1 3.7 0.2 0.6 78.0 0.9 0.8 17.8 13.4 0.9 9.1 34.6 0.1 21.6 27.5 16.4 50.0 8.9 84.7 55.1 53.9 28.7 1.5 0.1 4.9 16.4 0.2 23.0 0.3 1.3 0.1 2.2 0.7 239.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.8 1.8 3.9 1.1 3.0 2.0 3.5 2.3 4.7 4.9 2.9 3.5 16.0 36.0 1.0 0.0 19.6 8.6 23.2 23.9 29.3 17.1 10.8 16.1 7.2 9.1 14.7 0.0 13.7 0.1 29.3 3.9 14.0 2.1 8.3 2.1 3.3 3.0 0.0 11.8 1.9 27.3 7.8 16.8 14.4 1.3 7.3 1.8 0.6 2.1 6.7 18.8 5.0 2.0 1.3 11.1 2.2 1.2 0.5 8.8 0.0 3.1 11.3 0.0 1.5 0.4 16.4 7.3 0.0 0.0 10.2 15.4 11.4 11.3 0.8 0.0 26.4 2.8 0.5 3.8 30.6 27.7 13.3 0.4 3.5 9.3 11.4 IHH "BDA1, HHG2" ENSG00000163501 "Indian hedgehog signaling molecule" Q14623 2 219054424-219060921 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Developmental protein, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 14.0;intestine: 22.3;stomach 1: 15.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 31.5;Enteroendocrine cells: 49.2;Granulosa cells: 122.4;Intestinal goblet cells: 34.7;Proximal enterocytes: 18.8;Undifferentiated cells: 23.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.8;endometrial cancer: 30.9" "Region enriched" "Detected in single" 6 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 16.4;OE19: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 23000000 "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (1.63e-2)" "prognostic favorable (3.67e-6)" "unprognostic (4.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.28e-1)" "unprognostic (1.06e-1)" "unprognostic (5.86e-2)" "unprognostic (2.74e-1)" "unprognostic (6.31e-2)" "unprognostic (3.33e-3)" "unprognostic (1.81e-3)" "unprognostic (2.05e-1)" "unprognostic (5.31e-1)" "unprognostic (1.51e-2)" "unprognostic (2.91e-2)" 0.1 0.0 0.0 2.0 0.0 0.0 0.1 0.1 2.4 4.9 0.0 22.3 12.2 14.0 0.0 0.3 0.9 0.7 0.0 0.0 0.0 2.4 3.5 1.3 0.0 0.3 0.1 0.4 0.0 0.0 0.5 0.1 0.4 2.4 12.4 0.0 0.0 0.7 0.0 0.0 12.9 0.7 0.2 0.0 15.0 0.1 0.1 0.0 1.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.0 0.0 0.3 0.1 0.4 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 2.8 0.0 1.8 0.0 0.0 0.4 31.5 0.0 0.1 0.0 6.0 0.5 0.1 49.2 0.0 0.0 3.3 0.0 0.1 12.2 8.9 0.0 122.4 0.0 0.6 0.0 0.0 0.0 34.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 14.0 0.0 0.0 1.8 18.8 3.2 0.9 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 23.6 0.3 IKBKG "FIP-3, FIP3, Fip3p, IKK-gamma, IP1, IP2, NEMO, ZC2HC9" ENSG00000269335 "Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma" Q9Y6K9 X 154541199-154565046 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "DNA damage, Host-virus interaction, Transcription, Transcription regulation" "Disease variant, Ectodermal dysplasia, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000426, CAB010373" Uncertain Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "CAB010373: AB_2124846, HPA000426: AB_1851572" "unprognostic (7.53e-2)" "unprognostic (2.76e-3)" "unprognostic (1.09e-1)" "unprognostic (3.37e-3)" "unprognostic (9.77e-2)" "unprognostic (3.68e-1)" "unprognostic (9.22e-2)" "unprognostic (1.47e-1)" "unprognostic (9.16e-2)" "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (9.87e-2)" "unprognostic (3.57e-2)" "unprognostic (4.41e-2)" "unprognostic (2.78e-1)" "unprognostic (7.07e-2)" "unprognostic (1.36e-2)" 24.4 32.1 18.0 27.6 19.2 42.5 21.7 18.1 23.8 18.9 16.6 22.1 21.2 24.3 6.2 25.5 19.4 16.0 21.5 17.9 17.3 20.7 62.5 29.7 29.0 22.7 19.3 18.3 18.7 10.8 20.2 11.9 21.6 19.9 10.7 6.3 19.8 13.3 20.0 28.4 26.6 14.1 17.9 41.8 22.6 18.8 20.6 19.7 22.9 9.8 18.7 24.8 21.1 23.6 45.8 46.6 11.2 37.1 22.2 18.2 29.7 28.2 35.1 29.4 43.9 32.2 26.5 35.6 73.5 32.6 79.6 39.8 15.0 27.3 12.0 39.6 25.2 27.5 65.4 54.9 37.4 29.3 92.7 23.4 25.6 39.9 15.8 19.4 33.2 34.6 16.6 34.3 23.5 43.1 29.7 52.9 10.4 32.5 69.2 35.4 16.7 38.4 27.6 27.4 19.5 19.9 32.7 32.9 23.0 8.7 19.4 33.4 36.4 29.8 33.9 70.6 69.9 67.5 49.0 69.2 41.4 50.6 41.3 24.9 34.2 61.3 35.3 42.2 24.1 21.3 21.4 26.5 29.8 20.9 17.1 21.3 50.4 30.7 51.1 25.4 26.8 31.0 18.0 19.2 18.1 23.8 17.9 17.3 22.7 19.3 21.6 17.9 20.6 23.6 16.0 3.2 14.3 8.5 22.3 12.4 12.1 20.6 6.2 6.1 8.0 9.8 6.9 10.0 13.6 12.9 10.4 23.3 27.3 14.0 1.9 18.7 0.9 8.0 10.8 15.3 4.9 9.9 5.5 16.9 16.8 12.6 12.8 9.5 29.2 12.0 10.8 36.4 28.3 25.2 4.8 7.7 14.2 17.2 15.9 2.0 14.3 29.4 12.4 4.7 44.5 11.1 48.4 3.0 11.4 23.4 12.8 13.9 13.7 12.5 10.9 7.6 8.3 10.2 6.6 9.6 13.7 4.6 12.8 10.6 10.5 38.0 24.6 10.2 8.5 14.2 IL11RA ENSG00000137070 "Interleukin 11 receptor subunit alpha" Q14626 9 34650702-34661902 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Craniosynostosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 57.8;Late spermatids: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 36.8;HSkMC: 38.2" "Low region specificity" "Detected in all" "HPA013162, CAB032830, HPA036652" Supported "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB032830: AB_2123745, HPA013162: AB_2668790, HPA036652: AB_2675229" "unprognostic (7.76e-2)" "unprognostic (7.63e-2)" "unprognostic (1.05e-1)" "unprognostic (6.76e-3)" "unprognostic (1.67e-1)" "unprognostic (1.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.52e-2)" "unprognostic (1.89e-2)" "unprognostic (4.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (2.14e-1)" "unprognostic (1.51e-1)" "unprognostic (2.93e-2)" "unprognostic (8.71e-2)" 26.6 14.8 20.0 15.5 22.9 13.7 30.2 23.9 23.8 44.6 17.2 58.0 21.7 32.9 12.2 16.3 36.8 19.5 66.4 20.6 20.4 21.9 50.7 22.6 32.0 21.4 21.5 38.0 12.9 29.2 21.8 10.3 20.4 30.3 11.4 18.7 26.1 15.7 30.0 61.3 37.9 19.6 20.8 33.3 26.0 18.3 21.6 16.9 48.0 28.5 21.1 32.2 34.1 22.9 2.5 5.5 11.7 11.7 16.5 28.9 5.5 13.8 19.1 8.8 11.9 2.0 4.6 2.6 3.7 36.8 3.3 5.0 3.4 5.0 3.5 23.8 9.2 7.9 23.4 1.0 8.4 2.7 4.3 38.2 6.1 4.9 1.7 11.9 5.6 16.4 3.3 5.4 11.3 1.6 3.6 18.6 2.5 2.0 3.7 5.6 2.3 2.7 2.9 2.5 3.4 12.3 1.7 3.7 5.3 6.1 10.1 10.2 5.2 4.1 10.0 3.2 0.0 3.7 2.6 1.0 10.9 3.1 20.1 2.1 1.0 0.0 1.4 1.4 2.1 0.8 2.7 2.2 1.3 1.0 2.5 1.8 0.3 1.0 0.3 0.5 1.7 1.7 20.0 22.9 23.9 23.8 20.6 20.4 21.4 21.5 20.4 20.8 21.6 22.9 15.8 3.2 14.3 26.8 2.6 17.5 5.8 3.6 6.2 19.6 6.4 25.1 37.9 1.5 3.6 3.7 14.6 11.3 5.1 3.7 0.0 1.9 18.3 0.7 4.4 15.2 9.1 0.8 4.3 0.7 4.1 42.7 3.1 1.3 0.0 57.8 17.5 32.1 4.6 23.5 9.0 5.0 0.0 3.5 19.6 97.2 11.1 3.6 32.0 4.7 2.6 15.2 6.2 5.0 7.3 0.3 4.3 5.7 2.4 2.9 7.0 2.4 1.4 9.0 0.0 32.9 8.9 4.6 21.6 1.4 14.1 12.4 6.0 12.2 5.2 1.7 INPP5E "CORS1, JBTS1, pharbin, PPI5PIV" ENSG00000148384 "Inositol polyphosphate-5-phosphatase E" Q9NRR6 9 136428619-136439845 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Ciliopathy, Disease variant, Joubert syndrome, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065758 Approved Approved "Golgi apparatus,Focal adhesion sites" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus, Focal adhesion sites" "HPA065758: AB_2685554" "unprognostic (1.99e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-2)" "unprognostic (1.23e-2)" "unprognostic (4.00e-1)" "unprognostic (6.92e-2)" "unprognostic (9.60e-3)" "unprognostic (3.21e-1)" "unprognostic (5.81e-2)" "unprognostic (2.65e-2)" "prognostic favorable (1.82e-4)" "unprognostic (2.03e-1)" "unprognostic (3.04e-2)" "unprognostic (3.76e-1)" "unprognostic (5.48e-2)" "unprognostic (4.64e-1)" "unprognostic (2.66e-2)" 12.1 10.8 15.0 6.9 15.0 6.4 11.7 15.3 19.9 15.1 11.3 13.1 5.7 15.2 2.3 10.6 17.6 5.3 13.7 14.0 14.3 13.3 12.2 11.9 8.2 15.1 13.3 16.2 10.8 6.6 14.3 5.7 15.5 12.3 3.3 7.4 9.5 5.3 8.5 11.2 11.7 5.6 11.4 20.8 8.9 20.1 14.8 6.4 15.1 3.8 4.7 12.2 12.0 13.9 8.9 10.3 12.6 13.2 6.5 7.1 14.9 10.7 5.7 7.4 5.1 12.5 6.0 10.8 10.5 11.1 11.9 25.2 6.2 8.6 2.8 36.8 25.4 8.5 27.1 8.4 10.3 9.5 11.9 10.9 8.8 9.8 7.2 10.3 8.9 14.8 14.5 14.0 7.0 22.3 11.4 19.9 8.1 5.3 16.0 21.1 8.7 8.3 7.4 9.8 14.1 12.2 10.4 8.5 7.6 7.6 15.1 15.6 11.8 24.1 9.4 10.1 18.2 11.6 10.6 4.5 12.0 7.8 9.7 0.0 0.1 0.5 0.5 0.0 0.3 0.7 0.6 0.4 0.1 0.4 0.2 0.4 0.1 0.0 0.0 0.2 0.7 0.1 15.0 15.0 15.3 19.9 14.0 14.3 15.1 13.3 15.5 11.4 14.8 13.9 14.7 3.2 6.9 17.0 5.0 5.5 1.8 2.6 5.7 7.4 6.5 6.9 5.0 7.2 3.4 3.7 2.1 2.3 7.6 4.0 1.9 4.8 0.9 11.8 8.1 7.4 6.1 0.8 12.2 5.6 2.8 5.7 3.6 6.8 8.9 8.3 6.1 3.8 3.2 15.2 12.9 2.6 6.1 3.5 3.5 1.3 7.5 3.7 5.4 6.5 3.5 8.9 1.0 8.5 8.5 6.7 1.6 5.7 2.5 3.3 3.4 2.4 10.0 10.8 0.0 5.5 7.5 15.3 9.1 5.4 4.8 0.8 5.3 5.6 3.9 1.6 INPPL1 SHIP2 ENSG00000165458 "Inositol polyphosphate phosphatase like 1" O15357 11 72223701-72239147 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Immunity" "Actin-binding, Hydrolase" "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 344.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037601 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Golgi apparatus" "HPA037601: AB_10672281" "unprognostic (2.68e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.68e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (2.49e-2)" "unprognostic (3.54e-2)" "unprognostic (1.51e-2)" "unprognostic (1.64e-1)" "unprognostic (4.34e-2)" "unprognostic (3.66e-2)" "unprognostic (2.33e-1)" "unprognostic (2.88e-1)" "unprognostic (1.99e-3)" "unprognostic (2.07e-1)" 45.2 56.4 39.0 34.4 43.4 51.3 44.7 41.3 40.5 63.8 47.3 87.5 35.9 56.1 18.2 34.6 61.3 33.7 73.6 33.2 42.5 60.0 36.6 61.8 36.8 53.9 43.2 68.6 55.7 36.4 60.5 39.7 45.8 68.7 23.3 14.9 53.8 39.5 116.6 31.4 57.1 33.4 45.0 66.1 60.8 24.2 48.8 19.3 67.7 43.0 23.2 59.9 43.4 41.2 28.7 62.1 71.5 49.8 35.4 41.1 122.5 118.9 61.2 80.6 49.6 84.3 72.2 79.5 125.6 101.7 57.8 106.7 60.4 37.6 28.0 101.9 59.1 84.8 344.5 31.9 68.1 56.1 176.7 58.2 39.1 78.0 31.4 100.5 44.2 29.3 59.7 34.7 45.1 78.8 42.1 224.9 67.7 20.7 93.7 185.0 161.0 18.2 94.8 48.6 33.8 48.6 133.9 85.1 182.8 36.6 88.8 106.0 74.5 86.4 96.7 129.9 43.1 94.5 17.5 80.1 24.7 51.7 47.2 2.5 3.5 3.3 1.9 2.0 1.7 0.9 1.6 1.3 2.4 1.0 1.1 1.6 2.3 2.2 3.6 1.8 1.5 1.8 39.0 43.4 41.3 40.5 33.2 42.5 53.9 43.2 45.8 45.0 48.8 41.2 13.9 3.2 12.8 47.0 8.1 7.1 4.9 10.8 14.2 1.7 20.3 17.3 13.6 11.5 11.7 12.9 27.1 27.9 9.1 28.3 1.9 11.6 1.5 14.6 16.3 11.2 22.7 5.7 2.6 12.5 15.4 10.8 24.5 25.5 7.6 21.0 8.9 12.5 21.7 10.1 2.2 16.4 18.3 27.6 16.2 2.1 9.9 29.8 10.6 18.7 17.6 16.8 14.4 15.1 6.1 14.9 17.5 13.9 7.8 7.8 15.2 16.2 10.2 17.2 6.6 12.9 14.5 1.4 4.9 6.7 4.8 32.4 11.6 10.1 21.8 5.4 INSL3 "MGC119818, MGC119819, RLF, RLNL" ENSG00000248099 "Insulin like 3" P51460 19 17816512-17821574 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" Hormone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 409.3" "Cell type enriched" "Detected in some" 19 "Theca cells: 24080.8" "Cancer enriched" "Detected in many" 21 "testis cancer: 39.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Karpas-707: 5.7;PC-3: 2.6;SCLC-21H: 5.2;SH-SY5Y: 4.7" HPA028615 Enhanced "Secreted to blood" NA NA 566000 "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 52: Non-specific - Transcription" "HPA028615: AB_10600717" "unprognostic (3.25e-1)" "unprognostic (2.25e-4)" "unprognostic (3.50e-5)" "unprognostic (7.04e-2)" "unprognostic (1.74e-4)" "unprognostic (4.60e-2)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.44e-1)" "unprognostic (1.73e-1)" "unprognostic (4.46e-1)" "unprognostic (4.93e-2)" "unprognostic (9.51e-10)" "unprognostic (6.80e-3)" "unprognostic (1.41e-1)" "unprognostic (8.85e-2)" "unprognostic (1.09e-5)" 0.5 1.6 1.2 4.8 1.3 1.8 0.5 2.3 1.5 0.1 1.3 0.5 1.5 0.3 0.8 0.6 0.8 0.4 0.2 1.4 1.5 0.5 0.4 0.9 2.9 1.2 1.3 29.6 0.2 0.0 0.2 0.3 1.4 0.6 0.0 0.1 0.6 0.0 0.2 0.3 1.7 0.0 1.2 5.2 0.8 409.3 1.5 0.5 0.3 0.4 1.2 0.4 0.3 1.3 0.2 0.6 0.1 0.5 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.1 1.1 0.1 1.4 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.1 0.5 0.0 0.2 0.0 0.0 1.2 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 1.0 0.2 1.1 0.0 1.1 2.6 0.9 0.0 0.1 0.1 0.3 5.2 4.7 0.0 1.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.0 0.4 2.1 0.1 0.1 1.3 0.0 0.4 0.2 0.0 0.7 0.4 0.7 0.0 0.9 0.9 0.1 1.1 0.7 1.0 2.2 0.5 0.1 0.1 0.8 0.5 1.2 1.3 2.3 1.5 1.4 1.5 1.2 1.3 1.4 1.2 1.5 1.3 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 2.3 0.0 0.0 0.1 6.8 0.0 0.1 3.4 0.0 0.0 0.3 0.0 0.4 42.3 0.0 0.0 0.0 0.9 0.4 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 257.1 1240.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 998.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 2.9 5.7 0.0 0.0 0.5 0.8 24080.8 0.0 0.0 INTS8 "C8orf52, FLJ20530, INT8, MGC131633" ENSG00000164941 "Integrator complex subunit 8" Q75QN2 8 94813311-94881746 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057299 Approved Approved Nucleoplasm Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA057299: AB_2683403" "unprognostic (1.08e-2)" "unprognostic (3.12e-2)" "unprognostic (1.28e-1)" "unprognostic (5.86e-2)" "unprognostic (1.96e-1)" "unprognostic (4.81e-2)" "prognostic unfavorable (2.54e-6)" "unprognostic (3.07e-2)" "unprognostic (6.87e-2)" "unprognostic (9.77e-3)" "unprognostic (4.84e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.24e-1)" "unprognostic (5.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.96e-2)" 8.8 7.5 4.4 13.9 4.8 15.5 8.1 8.3 6.4 14.5 6.9 12.8 7.8 13.2 4.2 10.5 9.5 7.3 10.2 4.8 6.4 6.4 8.9 7.5 17.4 5.7 4.4 11.4 13.5 10.1 8.3 9.4 4.6 10.4 14.8 10.3 11.0 8.7 12.6 10.3 10.6 13.6 4.0 9.9 10.6 30.6 6.3 20.6 8.8 12.0 13.6 10.4 10.4 6.1 52.4 31.9 49.2 43.4 17.7 41.7 25.5 27.5 26.0 35.7 33.0 22.5 38.0 52.3 25.2 20.7 44.3 31.5 61.3 29.2 47.6 58.1 28.8 45.7 19.3 22.1 21.1 24.6 31.7 17.1 13.5 34.7 29.6 40.8 40.1 35.1 44.4 38.9 22.0 34.5 53.7 20.4 28.1 114.9 55.8 42.7 19.7 29.0 30.0 26.6 34.6 18.4 26.8 7.7 24.1 40.3 37.3 31.6 28.1 16.1 18.9 31.1 25.1 22.0 43.0 45.2 21.6 49.4 32.2 2.1 9.6 15.1 4.6 6.8 7.5 13.4 10.8 11.8 9.3 10.4 11.0 6.5 9.3 9.6 6.6 5.5 10.0 4.5 4.4 4.8 8.3 6.4 4.8 6.4 5.7 4.4 4.6 4.0 6.3 6.1 11.0 16.0 8.6 16.6 19.4 5.9 11.6 9.1 9.6 13.7 6.1 4.6 8.3 5.7 11.6 7.3 33.3 10.0 9.7 10.3 3.9 8.3 36.0 15.0 12.1 11.8 18.0 17.7 44.8 13.4 12.9 10.8 8.6 6.1 12.7 15.2 8.9 5.5 9.5 28.6 40.9 11.8 8.2 11.6 6.6 6.4 16.1 14.0 7.2 25.3 21.6 8.0 16.5 33.2 31.2 10.9 14.6 16.1 18.0 8.8 9.5 5.1 19.7 18.9 6.6 10.6 13.1 54.7 32.5 9.0 7.0 8.5 14.2 11.0 11.1 8.1 INTU "CPLANE4, KIAA1284, PDZD6, PDZK6" ENSG00000164066 "Inturned planar cell polarity protein" Q9ULD6 4 127623271-127726737 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 13.2" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Cone photoreceptor cells: 137.6;Endometrial ciliated cells: 81.4;Oligodendrocytes: 78.0;Respiratory ciliated cells: 84.0;Rod photoreceptor cells: 181.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036714, HPA036715, HPA061467" Approved Uncertain Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA036714: AB_10670238, HPA036715: AB_2675267, HPA061467: " "unprognostic (1.09e-1)" "unprognostic (2.89e-1)" "unprognostic (4.11e-2)" "unprognostic (1.38e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-1)" "unprognostic (2.88e-3)" "unprognostic (4.30e-2)" "unprognostic (2.91e-1)" "unprognostic (1.43e-1)" "unprognostic (3.90e-2)" "unprognostic (1.53e-1)" "unprognostic (1.22e-1)" "unprognostic (9.49e-2)" "unprognostic (3.28e-1)" "unprognostic (2.36e-1)" "unprognostic (5.33e-2)" 1.5 1.6 6.0 1.2 5.9 2.6 2.9 4.0 7.0 1.4 4.9 1.2 2.1 2.6 5.1 1.3 2.4 1.5 0.9 4.6 3.2 1.9 0.7 1.6 1.1 1.0 3.1 3.3 1.2 1.1 2.8 1.0 1.3 1.8 1.6 13.2 1.8 1.2 1.1 3.8 1.0 1.3 0.3 1.3 2.1 2.3 6.3 0.6 2.7 2.5 0.7 1.2 1.6 5.9 2.5 1.7 8.7 3.1 1.1 2.7 0.7 1.4 0.7 1.0 1.9 1.2 2.2 1.8 2.1 1.2 2.8 1.5 7.0 1.3 2.9 0.8 2.1 2.6 3.3 3.0 1.1 2.3 1.2 1.2 1.5 2.9 0.7 2.6 2.7 0.9 3.4 2.0 1.4 1.2 0.8 1.2 4.0 0.9 1.6 0.8 2.0 0.5 1.8 1.8 4.1 2.9 2.9 1.6 1.0 4.3 1.8 1.3 2.1 2.5 1.9 2.2 2.0 1.2 1.9 0.6 2.1 1.0 1.5 1.1 0.2 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 1.4 0.3 0.2 0.4 0.1 0.0 6.0 5.9 4.0 7.0 4.6 3.2 1.0 3.1 1.3 0.3 6.3 5.9 8.9 22.4 15.4 133.5 0.6 6.0 10.4 7.2 12.0 56.3 13.7 24.8 15.6 10.0 18.8 3.7 137.6 8.3 0.4 2.7 7.9 7.6 10.2 81.4 30.5 8.2 11.5 3.8 36.0 5.1 6.2 18.7 10.2 15.8 5.1 22.9 6.4 2.5 3.0 37.0 36.6 5.9 10.2 1.6 9.6 11.9 14.0 3.0 7.2 23.4 0.5 16.5 0.0 19.6 78.0 3.4 1.5 11.7 0.0 6.9 1.1 11.2 84.0 181.8 0.0 17.8 10.9 8.7 20.4 7.9 6.1 1.9 1.7 12.9 7.0 6.4 INVS NPHP2 ENSG00000119509 Inversin Q9Y283 9 100099243-100302175 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Calmodulin-binding, Developmental protein" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 132.9;Excitatory neurons: 144.8;Inhibitory neurons: 142.8;Microglial cells: 112.4;Oligodendrocyte precursor cells: 144.3;Oligodendrocytes: 233.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049994 Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA049994: " "unprognostic (3.84e-3)" "unprognostic (3.11e-2)" "unprognostic (1.74e-1)" "unprognostic (2.86e-2)" "unprognostic (6.73e-2)" "prognostic unfavorable (6.35e-4)" "unprognostic (3.53e-3)" "unprognostic (2.93e-3)" "unprognostic (1.99e-1)" "unprognostic (6.46e-2)" "unprognostic (1.15e-1)" "unprognostic (3.56e-2)" "unprognostic (1.34e-3)" "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (6.37e-2)" "unprognostic (1.83e-1)" 6.2 6.1 4.2 4.3 7.5 4.6 5.0 7.1 5.4 7.3 7.0 5.6 4.0 7.0 6.3 4.3 5.7 5.4 4.8 4.1 5.6 8.7 9.4 5.2 5.8 6.5 5.5 9.7 4.7 9.7 6.7 5.9 7.1 6.1 4.6 11.8 4.3 5.1 3.6 3.5 4.7 6.1 4.4 5.2 4.4 6.6 6.2 7.8 6.6 4.2 5.7 5.3 5.9 11.6 7.4 13.2 11.0 11.7 13.3 10.7 9.2 8.6 9.0 7.5 6.1 6.7 4.5 17.3 4.9 10.0 13.7 11.1 8.8 11.3 6.1 13.3 6.0 13.0 12.4 7.3 10.0 13.1 10.4 11.2 13.1 7.8 15.8 10.1 13.7 11.7 11.4 10.4 7.8 6.4 10.4 5.1 6.4 13.5 7.6 9.3 19.3 3.9 7.0 6.9 10.0 7.9 9.7 5.8 9.9 8.9 4.1 7.2 10.2 8.7 6.3 9.0 6.5 10.5 13.2 3.5 9.2 5.4 4.8 0.0 1.2 1.9 2.2 0.8 1.9 2.6 1.9 1.2 1.7 2.5 2.4 2.4 0.1 2.5 2.1 1.7 1.2 1.3 4.2 7.5 7.1 5.4 4.1 5.6 6.5 5.5 7.1 4.4 6.2 11.6 5.8 3.2 4.1 132.9 7.1 1.8 7.0 1.5 12.0 4.8 1.7 2.4 2.9 7.2 2.7 0.0 8.4 4.4 5.4 1.4 3.9 2.7 21.5 3.2 7.8 4.8 1.2 6.5 144.8 1.1 3.9 6.0 8.6 3.3 1.3 7.8 1.1 4.0 3.6 6.7 142.8 1.5 2.0 2.2 1.0 35.6 4.7 4.0 0.0 112.4 2.6 2.5 9.2 144.3 233.9 1.5 2.0 3.4 7.4 2.9 2.7 5.8 0.7 5.8 0.0 6.4 4.4 11.0 4.7 5.0 1.6 3.4 6.3 5.3 1.3 4.1 IQCB1 "KIAA0036, NPHP5, SLSN5" ENSG00000173226 "IQ motif containing B1" Q15051 3 121769761-121835079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 155.3;Spermatogonia: 96.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 131.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042028 Approved Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA042028: AB_2677806" "unprognostic (3.82e-2)" "prognostic favorable (1.77e-4)" "unprognostic (2.16e-1)" "unprognostic (4.10e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (3.08e-5)" "prognostic favorable (3.67e-4)" "unprognostic (1.42e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "unprognostic (6.78e-3)" "unprognostic (1.50e-3)" "unprognostic (2.59e-3)" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (4.75e-3)" 11.6 11.2 9.6 14.7 10.0 20.4 23.1 11.0 10.5 15.7 10.8 13.0 12.0 15.5 19.7 12.5 16.6 12.1 9.7 10.1 10.1 12.2 8.9 12.3 24.3 9.7 9.5 17.9 18.3 13.9 15.3 11.5 9.5 15.9 16.2 18.9 15.6 15.5 11.4 15.5 14.1 11.8 9.7 18.3 12.3 28.9 10.4 22.1 10.5 5.7 25.7 14.2 13.7 11.0 38.3 10.1 48.9 55.5 7.5 11.6 57.2 17.4 10.8 19.7 23.8 33.6 18.1 76.8 23.9 10.1 30.2 28.7 30.5 14.5 29.3 15.1 23.8 51.2 22.2 28.7 20.0 64.1 14.8 7.4 27.2 13.7 30.3 10.2 15.2 32.4 31.0 27.9 22.3 19.3 41.7 44.5 40.1 22.6 18.1 40.4 23.4 24.9 11.4 16.9 26.0 20.9 17.3 12.2 31.3 16.0 10.8 49.4 12.9 18.5 22.4 9.1 23.4 66.4 44.9 131.2 17.9 29.0 17.1 3.2 6.6 11.7 7.2 12.3 10.5 22.8 9.8 9.0 9.6 21.6 11.5 7.2 2.8 12.2 14.1 8.7 11.7 6.4 9.6 10.0 11.0 10.5 10.1 10.1 9.7 9.5 9.5 9.7 10.4 11.0 15.8 6.4 15.0 48.3 28.4 18.9 19.2 20.0 19.9 15.2 19.6 17.3 8.4 11.5 26.5 11.0 27.1 26.6 21.9 7.7 3.9 11.1 3.7 31.1 12.7 11.2 7.2 21.5 60.1 12.9 8.2 15.4 11.7 12.6 8.8 21.9 6.8 6.2 10.5 13.5 66.8 8.6 20.3 9.8 14.1 7.4 15.5 11.3 14.2 51.5 15.8 12.8 17.5 49.3 59.5 13.9 8.2 13.5 45.2 15.7 7.9 7.5 69.2 27.7 13.1 17.8 15.9 155.3 96.5 16.2 20.6 14.1 19.9 8.4 11.9 16.3 IQCE KIAA1023 ENSG00000106012 "IQ motif containing E" Q6IPM2 7 2558972-2614733 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 410.0;Late spermatids: 419.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.6" "Group enriched" "Detected in many" 4 "dendritic cells: 2.6;granulocytes: 4.6;monocytes: 1.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019515 Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 6: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA019515: AB_1851855" "unprognostic (2.29e-1)" "unprognostic (2.54e-1)" "unprognostic (3.78e-2)" "prognostic favorable (5.91e-4)" "unprognostic (7.96e-3)" "unprognostic (3.75e-1)" "unprognostic (2.54e-3)" "unprognostic (1.31e-1)" "unprognostic (4.04e-3)" "unprognostic (1.30e-2)" "unprognostic (1.66e-2)" "unprognostic (2.84e-1)" "unprognostic (2.04e-2)" "unprognostic (2.82e-2)" "unprognostic (6.97e-2)" "unprognostic (7.56e-3)" "unprognostic (3.13e-2)" 4.5 6.6 19.3 6.5 16.7 5.6 6.2 9.6 19.3 7.5 22.5 9.4 12.0 8.3 10.3 5.3 14.6 7.2 6.6 17.3 16.3 6.6 3.3 7.5 4.3 16.5 18.6 7.7 7.6 11.0 14.4 3.5 11.3 7.8 8.7 9.8 9.1 9.3 4.9 7.3 10.1 6.6 13.3 4.6 9.6 31.7 18.6 4.3 10.5 5.5 3.5 5.7 4.3 15.1 35.5 18.2 7.0 23.0 9.2 13.4 13.2 7.2 11.7 8.8 9.4 9.5 19.6 2.5 8.0 16.7 19.7 17.9 5.1 7.4 8.9 6.3 10.9 4.9 21.9 2.6 6.8 12.8 6.4 5.8 13.5 8.3 9.9 10.4 10.3 8.9 15.4 4.5 11.8 35.8 5.2 8.6 6.6 15.7 12.4 4.9 8.4 8.8 10.1 15.9 15.7 18.7 8.2 33.9 7.1 4.9 41.5 17.1 10.3 7.6 15.7 30.2 12.2 4.9 8.0 0.5 15.3 8.5 22.1 0.8 0.8 2.3 0.6 1.2 0.2 0.2 0.3 0.3 0.3 0.3 0.2 0.6 4.6 0.2 0.4 2.6 0.2 0.2 19.3 16.7 9.6 19.3 17.3 16.3 16.5 18.6 11.3 13.3 18.6 15.1 4.8 12.8 14.3 14.4 2.1 5.5 5.7 5.3 6.2 8.9 12.3 7.9 9.1 14.3 11.4 12.9 60.5 4.1 13.8 27.4 17.6 20.6 410.0 44.8 15.3 5.7 8.4 1.7 16.6 19.7 10.0 7.0 24.5 9.4 1.3 7.6 6.4 2.8 10.1 20.2 17.4 12.3 12.2 8.1 5.3 419.3 14.0 9.3 0.0 3.7 12.0 14.9 12.3 4.5 4.2 24.1 18.9 15.4 8.0 5.4 12.1 9.5 58.7 36.7 19.7 7.8 6.6 40.9 43.8 3.5 4.3 1.9 4.9 11.2 12.4 4.0 IRF6 "LPS, OFC6, VWS, VWS1" ENSG00000117595 "Interferon regulatory factor 6" O14896 1 209785617-209806175 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 95.4;skin 1: 114.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 387.2;Basal prostatic cells: 253.9;Basal squamous epithelial cells: 217.9;Squamous epithelial cells: 251.9;Suprabasal keratinocytes: 552.4;Urothelial cells: 290.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 10.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 61.9;HaCaT: 210.7;HBEC3-KT: 80.5;hTCEpi: 170.1;hTERT-HME1: 82.2;RT4: 78.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA063121, HPA076162" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "HPA063121: AB_2684942, HPA076162: AB_2686780" "unprognostic (2.59e-1)" "unprognostic (1.79e-3)" "unprognostic (1.74e-1)" "unprognostic (7.80e-2)" "unprognostic (1.33e-2)" "unprognostic (4.94e-3)" "unprognostic (1.46e-1)" "unprognostic (1.36e-1)" "unprognostic (7.82e-2)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (2.70e-1)" "unprognostic (2.66e-2)" "unprognostic (2.14e-1)" "unprognostic (4.42e-2)" 1.6 11.4 1.6 3.2 1.5 2.8 35.9 10.9 1.8 21.6 5.2 27.1 26.9 5.9 49.3 95.4 21.7 10.8 29.7 1.7 1.4 17.0 33.3 8.8 0.9 1.9 2.9 1.9 19.7 26.4 6.5 20.4 1.9 32.4 31.5 2.4 39.0 26.4 0.5 114.0 25.0 2.0 2.1 2.1 24.8 2.9 2.3 20.3 17.1 2.7 23.0 40.5 46.8 1.2 61.9 0.0 0.0 0.0 0.4 0.0 20.9 0.1 0.5 0.1 0.3 13.6 20.7 0.0 0.1 0.1 0.0 210.7 0.0 80.5 0.0 0.0 1.3 0.1 0.2 0.0 0.2 0.0 0.2 0.1 170.1 0.1 82.2 0.0 3.7 0.0 0.1 0.2 0.0 8.3 0.0 0.3 1.2 17.0 0.2 0.0 0.0 0.3 7.7 78.8 18.7 6.1 1.4 34.1 1.9 3.8 24.1 0.3 0.0 0.0 0.1 0.0 0.3 0.8 15.8 0.1 0.2 0.0 0.2 0.0 0.0 0.4 0.6 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.2 1.6 1.5 10.9 1.8 1.7 1.4 1.9 2.9 1.9 2.1 2.3 1.2 1.9 16.0 10.4 0.3 1.0 387.2 253.9 154.0 217.9 0.1 47.2 33.3 26.0 32.9 70.4 35.0 0.0 94.2 1.3 95.5 27.4 36.7 1.1 120.2 9.5 6.0 59.9 0.4 0.0 19.2 25.4 4.5 53.0 121.7 2.5 0.0 1.1 35.9 8.3 0.0 0.1 74.9 38.7 1.0 30.1 0.7 0.6 2.3 35.6 1.9 1.0 6.5 0.0 0.0 0.0 49.2 43.8 0.0 2.5 153.9 49.5 11.9 82.1 0.6 0.0 0.4 7.4 8.2 3.7 251.9 552.4 161.6 2.5 0.7 44.5 290.3 IRX5 IRX-2a ENSG00000176842 "Iroquois homeobox 5" P78411 16 54930865-54934485 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Vision" DNA-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 14.0;skin 1: 16.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 40.3;Breast myoepithelial cells: 55.5;Granulosa cells: 43.8;Muller glia cells: 43.1;Squamous epithelial cells: 33.9" "Cancer enhanced" "Detected in many" "breast cancer: 20.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 27.1;T-47d: 36.6;THP-1: 20.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA047130 Approved "Nuclear speckles,Microtubules,Cytosol" No NA "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "Microtubules, Cytosol" "HPA047130: AB_10962983" "unprognostic (2.63e-1)" "unprognostic (4.49e-2)" "unprognostic (8.03e-2)" "unprognostic (8.56e-2)" "unprognostic (1.42e-2)" "unprognostic (3.89e-2)" "unprognostic (5.38e-3)" "prognostic favorable (4.59e-4)" "unprognostic (8.52e-2)" "unprognostic (1.02e-1)" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (1.17e-3)" "unprognostic (3.34e-2)" "unprognostic (8.90e-2)" "unprognostic (1.77e-3)" "unprognostic (4.28e-2)" 1.7 0.6 1.3 0.0 1.5 0.0 14.0 4.1 0.4 1.8 0.3 0.2 0.0 0.1 0.0 7.2 0.2 0.1 9.8 0.3 1.9 6.9 0.0 6.4 0.0 3.6 4.1 0.3 0.1 0.3 0.4 0.0 3.1 3.4 0.0 1.3 10.2 0.2 1.4 16.9 0.0 0.0 3.6 0.0 2.6 0.7 4.6 0.3 0.1 1.1 0.0 0.6 5.9 3.5 0.8 0.5 8.6 3.2 3.1 0.6 0.4 3.3 8.2 1.1 0.8 1.9 0.8 0.0 0.7 4.5 0.3 8.4 3.0 3.6 0.6 6.0 4.1 0.9 3.4 0.0 0.1 2.0 3.3 0.8 15.1 5.4 2.3 1.5 0.0 4.8 0.5 0.0 6.2 3.3 9.6 12.3 0.1 1.3 2.4 5.0 4.4 0.5 27.1 0.2 2.9 3.0 1.4 7.3 3.9 0.0 36.6 20.2 0.5 5.9 0.2 4.2 1.3 3.6 2.3 2.9 9.6 3.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 4.1 0.4 0.3 1.9 3.6 4.1 3.1 3.6 4.6 3.5 2.4 9.6 21.9 0.0 0.1 8.3 9.7 6.7 15.9 8.6 40.3 55.5 11.1 0.0 15.4 0.0 0.0 0.2 1.0 0.2 0.0 0.3 1.0 9.6 1.2 1.6 0.0 0.0 0.0 0.6 0.0 5.3 7.7 12.2 0.0 43.8 0.0 0.0 0.2 1.7 0.0 0.8 4.1 0.0 2.7 2.4 0.0 0.6 5.4 0.0 0.0 43.1 0.0 0.0 0.0 2.9 0.3 0.0 0.3 4.8 0.0 1.5 13.0 1.9 0.0 8.3 5.2 0.7 2.8 33.9 8.0 0.0 0.4 0.0 0.5 8.5 ITGA3 "CD49c, GAP-B3, MSK18, VCA-2, VLA3a" ENSG00000005884 "Integrin subunit alpha 3" P26006 17 50055968-50090481 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 111.9;Exocrine glandular cells: 105.1;Pancreatic endocrine cells: 245.6;Urothelial cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 647.2;hTERT-RPE1: 572.8;RPTEC TERT1: 562.0;U-87 MG: 920.8;WM-115: 570.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008572, CAB018594" Enhanced Supported "Plasma membrane" NA NA 170000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "CAB018594: AB_668044, HPA008572: AB_2668094" "unprognostic (3.24e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (9.51e-2)" "unprognostic (3.46e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (8.28e-3)" "unprognostic (2.76e-3)" "unprognostic (1.26e-3)" "unprognostic (1.82e-2)" "prognostic unfavorable (5.95e-5)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (2.35e-2)" 17.5 29.8 5.3 9.9 5.4 0.4 17.3 6.0 6.1 14.8 5.2 25.4 30.4 21.3 11.7 24.1 24.5 17.9 13.2 5.0 10.9 68.9 2.2 65.8 3.0 7.5 6.6 12.8 15.9 17.7 21.1 26.7 11.9 19.5 15.5 4.4 19.4 15.7 9.0 30.8 26.7 15.6 4.2 11.1 24.5 2.1 7.8 5.9 43.5 4.1 6.2 46.7 17.1 4.0 181.8 234.9 1.4 7.5 4.3 17.5 37.3 83.4 177.9 123.1 93.2 5.3 276.2 0.4 507.9 59.5 400.4 126.8 2.2 647.2 73.9 22.9 3.5 0.1 56.8 1.6 105.1 0.3 5.0 21.6 313.5 123.2 540.7 572.8 91.6 9.1 0.1 2.6 236.0 52.9 0.7 0.5 5.5 81.2 141.0 0.4 12.1 13.7 562.0 311.1 9.7 3.9 89.8 12.2 205.0 56.2 21.1 2.4 200.8 541.8 169.4 5.6 329.5 8.1 14.2 5.9 920.8 1.9 570.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 5.4 6.0 6.1 5.0 10.9 7.5 6.6 11.9 4.2 7.8 4.0 8.5 54.5 30.1 3.6 3.4 57.4 63.5 63.5 48.3 18.0 17.1 32.0 5.3 27.1 26.2 77.3 25.0 2.8 1.3 91.2 0.0 111.9 0.5 26.4 3.1 14.7 14.5 0.0 24.3 105.1 3.2 5.3 47.4 20.7 3.8 3.4 8.9 0.3 1.1 3.3 20.0 25.1 16.2 1.2 8.2 0.6 1.8 2.0 17.8 8.4 4.3 3.1 2.1 3.0 0.8 245.6 26.7 4.1 4.5 72.6 69.6 4.4 21.7 16.2 13.1 5.6 23.4 0.5 1.6 17.0 23.2 1.8 3.8 0.9 44.7 104.2 ITGA6 CD49f ENSG00000091409 "Integrin subunit alpha 6" P23229 2 172427354-172506459 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 327.2;Basal keratinocytes: 244.7;Urothelial cells: 247.6" "Cancer enhanced" "Detected in all" "head and neck cancer: 144.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 22.9" "Group enriched" "Detected in many" 28 "granulocytes: 22.9;NK-cells: 7.1;T-cells: 12.8" "Cell line enhanced" "Detected in many" "BJ: 326.2;HaCaT: 356.8;HBEC3-KT: 705.8;hTCEpi: 298.9;hTERT-HME1: 301.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009009, HPA012696, HPA027582" Enhanced NA NA 3300000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB009009: AB_2128038, HPA012696: AB_1851822, HPA027582: AB_10602606" "unprognostic (1.02e-1)" "unprognostic (3.33e-1)" "unprognostic (2.59e-2)" "unprognostic (5.96e-2)" "unprognostic (4.93e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.19e-1)" "unprognostic (1.61e-3)" "unprognostic (9.34e-2)" "unprognostic (6.01e-2)" "unprognostic (1.85e-3)" "unprognostic (1.84e-1)" "prognostic favorable (2.35e-11)" "unprognostic (3.35e-2)" "unprognostic (3.32e-1)" "unprognostic (2.98e-2)" "unprognostic (1.21e-3)" 45.9 8.3 20.1 27.8 16.7 5.8 55.6 16.6 20.3 64.3 42.8 65.4 74.2 43.1 9.5 25.1 25.3 37.2 29.2 17.2 20.9 42.7 8.8 29.3 18.7 20.8 18.8 5.6 42.0 14.0 6.2 76.8 19.3 24.4 62.4 7.3 81.0 30.8 27.7 46.6 67.4 39.0 20.5 41.2 66.1 26.1 25.0 33.9 21.1 42.6 21.4 55.0 26.8 16.5 77.5 64.8 26.7 49.1 1.4 0.9 146.3 326.2 34.6 32.1 20.0 36.2 141.3 0.7 90.9 86.8 73.8 356.8 17.7 705.8 58.1 0.7 16.6 1.9 64.8 58.7 4.8 21.4 2.4 6.2 298.9 2.0 301.4 32.9 209.6 40.8 0.3 5.5 41.6 3.7 5.9 17.8 48.2 214.2 54.5 1.1 82.3 1.6 48.0 106.6 0.8 3.4 61.2 0.1 69.7 28.0 13.1 1.4 97.9 44.9 41.1 84.2 56.8 4.8 3.6 1.9 1.7 7.2 185.0 4.4 0.2 22.9 5.3 0.0 10.7 0.2 6.7 6.4 0.1 0.5 12.8 5.9 0.7 7.1 0.0 0.0 8.1 4.3 20.1 16.7 16.6 20.3 17.2 20.9 20.8 18.8 19.3 20.5 25.0 16.5 327.2 9.6 19.5 88.5 8.8 244.7 236.4 43.4 88.8 1.4 55.0 72.8 32.5 22.8 10.5 27.6 56.3 103.8 14.4 139.6 5.9 34.4 31.2 82.5 34.8 196.0 57.4 1.7 4.0 62.1 26.5 20.8 219.7 149.3 8.2 103.4 11.7 21.5 25.5 1.7 6.1 128.8 20.3 3.2 20.8 46.8 4.1 10.0 51.6 119.9 1.7 1.3 29.9 1.5 8.8 127.9 104.2 2.6 109.0 184.8 54.5 52.2 9.2 13.9 0.0 11.8 18.4 7.7 20.2 141.5 84.0 22.3 30.1 44.0 146.3 247.6 ITGA8 ENSG00000077943 "Integrin subunit alpha 8" P53708 10 15513954-15719922 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 37.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.8;Inhibitory neurons: 56.1;Microglial cells: 34.7;Oligodendrocyte precursor cells: 64.8;Plasma cells: 25.5;Sertoli cells: 52.6;Smooth muscle cells: 57.6" "Cancer enhanced" "Detected in many" "prostate cancer: 6.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 8.4;HMC-1: 19.8;HSkMC: 8.7;U-266/84: 9.7" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 14.1" HPA003432 Approved Approved "Plasma membrane" NA NA 200000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA003432: AB_1851825" "unprognostic (2.15e-1)" "unprognostic (1.22e-3)" "unprognostic (1.05e-2)" "unprognostic (2.03e-1)" "unprognostic (1.25e-2)" "unprognostic (8.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "unprognostic (6.82e-2)" "unprognostic (3.80e-1)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (4.10e-3)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (2.26e-1)" "unprognostic (6.03e-2)" 8.6 10.5 1.6 2.1 2.1 0.1 2.7 1.9 5.0 23.8 8.0 6.1 6.7 9.7 5.5 9.8 8.8 6.7 7.7 7.0 0.9 10.0 0.7 20.8 3.2 1.5 2.8 5.7 0.8 4.7 3.2 0.2 1.1 37.4 6.1 1.6 1.8 30.8 2.9 3.3 6.8 9.1 1.5 19.9 19.3 0.6 1.5 1.0 5.6 6.9 4.4 15.7 9.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 8.4 2.5 0.0 0.0 0.0 0.0 19.8 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 9.7 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.1 1.9 5.0 7.0 0.9 1.5 2.8 1.1 1.5 1.5 2.2 1.2 0.0 1.3 0.7 2.4 1.0 1.9 0.0 0.6 6.3 0.1 0.3 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 4.0 11.4 0.0 0.0 82.8 0.0 0.0 10.1 0.0 0.2 0.0 0.0 4.2 0.0 0.1 0.0 56.1 0.0 0.0 0.0 1.8 0.1 0.9 0.5 1.8 34.7 0.0 13.6 0.0 64.8 4.0 0.0 0.0 0.0 25.5 1.5 0.0 0.0 0.0 0.3 52.6 11.3 57.6 0.0 0.2 0.4 1.1 0.0 1.2 0.1 0.1 1.4 ITGB4 CD104 ENSG00000132470 "Integrin subunit beta 4" P16144 17 75721328-75757818 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 200.6;skin 1: 205.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 173.6;Distal enterocytes: 133.3;Gastric mucus-secreting cells: 165.1;Pancreatic endocrine cells: 284.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 897.3;HaCaT: 345.1;HBEC3-KT: 768.6;hTCEpi: 256.9;RT4: 254.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 37.4" "CAB002422, CAB005258, HPA036348, HPA036349" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 980000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cell Junctions" "CAB002422: AB_563480, CAB005258: AB_2129021, HPA036348: AB_2675077, HPA036349: AB_2675078" "unprognostic (3.17e-3)" "unprognostic (3.52e-1)" "unprognostic (4.19e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (6.11e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.39e-4)" "unprognostic (1.02e-1)" "unprognostic (2.23e-2)" "unprognostic (1.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" 39.2 5.3 82.8 12.4 87.8 1.6 66.6 74.9 91.8 58.4 76.4 87.5 56.9 24.0 3.6 101.2 43.8 20.0 22.7 80.5 86.9 18.2 5.6 18.4 4.5 104.6 104.8 8.5 24.5 2.8 21.1 35.4 82.6 85.3 15.7 8.7 200.6 18.5 6.8 205.9 75.5 6.4 102.4 76.9 79.9 4.9 82.0 4.1 17.6 6.0 7.2 58.4 98.8 99.6 172.7 148.5 0.3 2.1 0.4 1.3 199.2 0.7 0.6 0.5 0.9 16.1 897.3 0.1 31.5 0.3 1.3 345.1 1.0 768.6 0.5 0.7 0.6 0.9 39.6 17.0 1.2 0.2 1.8 1.1 256.9 0.6 159.2 18.0 5.5 0.6 0.5 15.7 0.1 95.8 2.0 2.0 1.0 92.8 127.8 2.7 4.4 2.2 204.8 254.9 0.2 1.9 4.9 15.2 2.2 5.3 63.9 1.5 16.9 4.6 7.8 0.7 1.9 5.6 2.1 0.7 2.0 0.8 2.7 0.0 0.2 0.0 0.4 0.4 1.1 0.7 0.1 0.5 0.0 2.0 0.4 0.3 0.7 0.0 0.0 4.6 0.8 0.4 82.8 87.8 74.9 91.8 80.5 86.9 104.6 104.8 82.6 102.4 82.0 99.6 26.9 12.8 2.2 50.3 1.4 49.5 45.1 173.6 67.2 0.3 21.2 36.6 7.5 25.8 38.9 23.9 2.1 89.8 1.8 133.3 1.9 33.3 0.4 61.3 5.7 26.8 9.6 0.8 0.7 28.8 20.2 5.2 165.1 60.2 2.5 1.1 17.9 0.4 9.4 0.0 0.7 59.2 18.3 0.3 5.4 0.4 3.7 1.9 12.4 1.9 0.1 34.4 0.0 1.5 0.7 284.4 68.4 1.5 2.6 17.1 94.0 2.6 53.3 1.0 0.0 1.2 5.0 1.1 8.2 28.1 13.1 111.1 1.8 0.5 60.1 42.0 ITM2B "BRI, BRI2, BRICD2B, E25B, E3-16" ENSG00000136156 "Integral membrane protein 2B" Q9Y287 13 48232612-48270357 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Amyloidosis, Deafness, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 4375.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 4375.2" "Cell line enhanced" "Detected in all" "HMC-1: 731.2;RPTEC TERT1: 1718.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029292, HPA071992" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 5800000 "Cluster 5: Granulocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus, Vesicles" "HPA029292: AB_10601917, HPA071992: AB_2686480" "unprognostic (4.66e-2)" "unprognostic (2.02e-1)" "unprognostic (1.03e-2)" "unprognostic (1.00e-1)" "unprognostic (4.41e-2)" "unprognostic (6.84e-2)" "unprognostic (2.52e-1)" "unprognostic (1.29e-1)" "unprognostic (9.88e-2)" "unprognostic (2.42e-1)" "unprognostic (5.89e-2)" "unprognostic (2.87e-2)" "prognostic favorable (3.73e-5)" "unprognostic (4.38e-2)" "unprognostic (4.09e-2)" "unprognostic (6.00e-2)" "unprognostic (1.22e-1)" 510.2 367.4 286.9 172.5 301.0 125.6 323.8 328.6 489.0 416.1 406.6 260.1 289.2 388.8 1171.8 399.9 305.4 257.5 381.0 320.1 339.2 1306.3 391.2 376.1 236.7 334.9 308.0 507.2 179.6 233.7 290.5 573.8 304.4 312.5 191.4 174.4 408.7 386.2 164.7 399.6 287.4 232.5 373.6 435.2 312.8 121.4 308.8 188.3 386.1 206.2 187.4 305.1 402.2 394.8 67.6 51.8 73.1 116.3 348.5 254.5 119.2 215.0 202.2 87.5 100.6 29.1 248.3 16.6 168.8 121.6 48.5 214.1 61.3 107.0 107.4 69.9 147.3 137.9 29.0 99.0 138.5 140.6 731.2 113.4 149.1 45.1 62.0 375.7 131.2 78.3 24.5 90.9 174.8 29.6 200.4 310.1 266.0 116.5 103.6 100.1 100.5 73.6 1718.9 268.6 26.2 119.5 154.5 110.2 111.0 306.0 74.0 119.4 180.5 62.9 73.8 95.7 85.4 72.9 59.6 2.5 78.0 75.3 155.3 3091.4 864.5 2737.9 387.4 661.3 512.5 235.3 523.1 476.4 428.9 245.3 551.3 466.8 4375.2 356.5 692.7 196.2 563.4 1723.5 286.9 301.0 328.6 489.0 320.1 339.2 334.9 308.0 304.4 373.6 308.8 394.8 1380.0 695.5 300.4 174.6 408.6 862.4 1661.1 2606.2 1006.2 653.1 460.1 573.5 384.8 722.0 1121.9 1991.8 187.7 1164.3 448.2 754.2 545.9 910.2 23.6 751.8 802.2 1166.2 283.3 307.0 114.2 682.9 2362.8 1334.0 302.8 1177.2 578.0 421.2 1319.7 557.3 2117.8 353.3 142.6 503.2 1129.1 1569.8 900.6 76.7 1867.0 1381.5 681.3 252.0 1415.7 1634.9 425.3 174.4 237.9 515.7 788.3 2011.6 445.4 922.5 1259.3 2748.9 795.6 219.4 1222.7 602.4 1022.9 143.6 256.4 1384.6 1149.6 1471.5 723.2 665.5 440.9 1613.4 JAG1 "AGS, AHD, AWS, CD339, HJ1, JAGL1" ENSG00000101384 "Jagged canonical Notch ligand 1" P78504 20 10637684-10673999 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 211.1;Endometrial ciliated cells: 197.4;Smooth muscle cells: 190.1;Squamous epithelial cells: 343.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 219.2;hTERT-HME1: 131.1;U-251 MG: 187.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010343, HPA021555" Supported Approved "Golgi apparatus,Plasma membrane" NA NA 25000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus, Plasma membrane" "CAB010343: AB_649685, HPA021555: AB_1851969" "unprognostic (2.23e-1)" "unprognostic (2.04e-2)" "unprognostic (1.78e-1)" "unprognostic (4.15e-2)" "unprognostic (1.21e-1)" "unprognostic (6.42e-2)" "unprognostic (4.21e-2)" "unprognostic (8.94e-3)" "unprognostic (6.07e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (4.10e-6)" "unprognostic (5.48e-2)" "unprognostic (1.71e-3)" "unprognostic (2.22e-1)" "unprognostic (1.66e-1)" "unprognostic (3.10e-1)" "unprognostic (1.41e-3)" 44.2 10.1 10.3 13.0 9.5 21.8 30.3 8.4 12.0 44.0 8.9 23.7 13.8 27.3 19.5 52.4 27.0 21.6 20.7 12.8 9.8 21.7 6.2 23.9 8.4 12.4 14.2 20.3 22.0 20.9 8.2 67.9 10.0 25.9 23.0 22.1 15.8 26.7 9.8 57.2 13.6 23.6 9.7 23.3 25.1 4.5 12.1 9.3 19.9 22.8 15.6 28.5 50.0 8.5 4.1 20.6 63.1 78.1 11.8 11.3 2.3 2.4 11.9 3.3 1.8 18.5 11.2 0.7 59.0 2.4 17.7 85.8 9.4 219.2 2.7 0.2 4.5 7.0 2.2 87.9 5.8 28.4 0.5 4.6 63.7 10.6 131.1 12.5 21.1 0.3 0.1 8.8 6.0 0.2 0.0 20.2 18.2 68.7 20.3 5.3 3.9 13.1 29.9 25.6 2.8 2.1 6.3 4.4 26.2 49.8 0.3 3.3 80.5 14.2 9.9 11.8 187.9 3.6 0.6 0.9 9.1 10.3 11.3 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.0 10.3 9.5 8.4 12.0 12.8 9.8 12.4 14.2 10.0 9.7 12.1 8.5 73.0 41.7 15.4 5.9 1.1 104.6 54.9 76.3 211.1 9.7 13.2 29.1 20.6 30.0 34.4 16.5 43.8 16.9 6.8 64.3 1.9 31.6 5.0 197.4 22.2 102.5 5.3 0.0 6.9 30.4 1.0 41.9 76.0 96.4 7.0 2.7 60.0 1.8 4.2 21.9 9.2 12.8 20.3 5.9 33.9 9.6 21.5 9.1 14.2 22.5 2.8 11.9 2.1 24.6 1.3 97.3 18.3 33.8 4.3 24.5 7.8 2.3 30.2 69.1 85.5 46.7 190.1 0.9 3.2 343.9 106.8 2.2 4.3 107.2 39.1 33.7 JUP "CTNNG, DP3, DPIII, PDGB, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 952.2;skin 1: 932.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 315.9;Pancreatic endocrine cells: 356.2;Squamous epithelial cells: 318.3;Suprabasal keratinocytes: 383.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.1;eosinophil: 28.7;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.5;naive B-cell: 11.7;non-classical monocyte: 43.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 1090.1;OE19: 3919.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" 46.5 16.0 13.6 23.6 21.6 20.7 68.6 20.8 18.9 243.7 25.8 94.9 88.1 57.0 15.3 952.2 69.9 39.8 145.1 14.6 14.3 120.7 70.9 57.1 15.7 20.7 16.2 46.2 59.6 19.9 37.3 51.5 19.6 68.0 49.0 4.7 226.4 41.8 110.8 932.4 95.7 23.1 14.8 22.7 86.3 12.5 16.2 29.6 86.4 62.2 92.0 68.7 432.6 33.6 268.8 217.8 21.7 18.5 0.2 0.1 330.6 15.3 89.2 5.9 5.2 332.6 289.0 5.4 157.8 9.7 7.5 1090.1 31.6 242.4 1.0 0.6 74.2 11.6 165.1 74.4 34.7 7.3 113.6 0.5 538.6 0.9 43.9 64.2 96.1 7.0 99.6 94.0 0.0 342.6 1.9 96.5 42.3 3919.9 36.2 313.5 0.2 202.5 165.8 674.0 52.2 38.6 33.8 652.1 1.9 98.6 545.9 8.0 152.4 0.3 14.8 6.8 5.1 8.2 31.2 5.5 1.5 12.7 2.6 3.9 13.1 28.7 0.0 22.6 0.0 13.5 0.0 0.2 14.5 11.7 0.2 0.1 0.6 0.8 43.8 4.5 0.1 5.7 13.6 21.6 20.8 18.9 14.6 14.3 20.7 16.2 19.6 14.8 16.2 33.6 56.9 60.9 36.8 4.6 10.6 196.9 218.5 104.5 100.2 1.9 87.3 77.0 87.8 48.6 80.9 132.4 4.2 98.9 1.1 315.9 27.4 212.2 28.5 112.6 21.1 55.2 66.8 3.4 0.5 135.4 167.3 25.6 136.1 247.0 11.4 16.5 41.4 34.1 14.4 0.0 1.6 125.0 81.4 7.7 32.7 8.3 5.0 10.9 12.4 2.8 6.3 18.2 0.0 7.1 13.6 356.2 223.7 0.0 3.9 220.1 141.1 35.6 45.7 4.3 6.6 37.4 18.8 2.5 4.5 318.3 383.3 185.7 6.1 3.2 129.2 301.6 KAT6B "Morf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B" ENSG00000156650 "Lysine acetyltransferase 6B" Q8WYB5 10 74824927-75032624 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006104 Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" "HPA006104: AB_1079445" "unprognostic (4.17e-1)" "unprognostic (1.98e-1)" "unprognostic (1.82e-1)" "unprognostic (2.32e-2)" "unprognostic (7.83e-2)" "unprognostic (2.85e-2)" "unprognostic (3.56e-1)" "unprognostic (2.62e-1)" "unprognostic (2.54e-1)" "unprognostic (1.09e-1)" "unprognostic (9.47e-2)" "unprognostic (8.78e-2)" "prognostic favorable (4.82e-4)" "unprognostic (2.52e-1)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (3.15e-1)" 7.6 6.3 5.0 3.1 5.6 8.8 7.3 5.6 5.3 10.5 2.0 9.6 3.2 9.2 5.2 6.9 8.3 3.8 7.5 5.7 4.0 4.3 4.6 6.5 4.4 3.1 3.5 12.2 8.6 10.5 7.4 4.4 3.0 6.5 4.1 6.4 7.3 4.3 11.8 8.0 8.1 6.0 3.0 5.4 9.3 7.8 5.6 9.8 7.3 6.0 4.1 9.1 8.9 4.9 4.7 4.4 8.0 6.9 6.2 9.2 4.1 4.1 7.5 3.4 3.6 3.4 5.3 9.8 2.1 7.1 3.5 3.8 4.2 3.3 5.6 4.2 6.8 3.6 3.9 4.5 4.5 8.6 2.4 5.9 5.3 4.5 6.9 10.5 3.8 7.7 3.9 9.0 4.2 4.7 8.2 4.3 5.0 4.9 25.7 12.7 4.3 2.4 2.3 2.3 4.2 6.9 4.1 7.4 3.7 2.8 4.5 3.2 4.7 4.6 5.5 3.1 3.8 6.4 8.1 6.4 5.0 8.9 1.3 1.7 1.3 1.6 2.3 1.0 2.6 2.2 1.9 2.1 1.1 2.8 2.9 2.6 1.8 4.4 1.1 1.7 1.7 1.0 5.0 5.6 5.6 5.3 5.7 4.0 3.1 3.5 3.0 3.0 5.6 4.9 34.5 44.8 53.7 90.1 48.1 19.9 20.8 16.3 74.6 52.8 36.7 27.3 53.9 12.8 29.3 9.2 68.8 10.4 51.8 22.5 9.8 12.7 6.2 41.1 72.7 24.9 23.8 32.0 130.2 18.0 10.6 44.4 57.6 50.8 41.7 68.0 18.9 16.0 11.0 43.7 131.2 21.7 12.2 12.3 15.0 8.3 42.3 24.1 14.2 41.2 13.6 45.5 42.2 101.0 92.1 10.5 19.4 40.3 62.5 21.0 17.8 10.2 28.6 52.5 26.3 55.3 44.1 33.1 32.2 46.6 17.5 22.7 59.7 27.1 17.5 23.5 KATNB1 ENSG00000140854 "Katanin regulatory subunit B1" Q9BVA0 16 57735739-57757244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041165, HPA041839" Enhanced Supported "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" Microtubules "HPA041165: AB_10795584, HPA041839: AB_10795598" "unprognostic (1.37e-1)" "unprognostic (2.76e-2)" "unprognostic (1.56e-1)" "prognostic favorable (9.24e-4)" "unprognostic (2.54e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.42e-1)" "unprognostic (2.92e-1)" "unprognostic (1.75e-1)" "prognostic favorable (8.44e-4)" "unprognostic (2.89e-2)" "unprognostic (1.03e-3)" "unprognostic (2.20e-1)" "unprognostic (1.29e-1)" "unprognostic (6.88e-2)" "unprognostic (1.54e-1)" 9.9 13.3 16.0 10.8 18.4 23.0 10.6 5.5 24.7 10.1 11.8 9.9 10.6 11.2 4.1 15.9 19.2 6.2 11.7 18.2 11.7 10.3 9.5 11.9 10.5 10.4 9.1 9.6 14.0 10.7 13.7 7.2 10.1 10.2 5.5 5.9 13.1 7.7 10.4 29.0 10.1 6.5 6.6 12.9 10.3 37.1 13.2 12.8 11.0 7.9 8.2 8.7 11.9 16.3 20.8 35.7 19.2 25.0 10.4 9.2 35.2 13.9 18.5 35.2 19.6 30.2 18.3 16.1 28.0 8.8 13.2 27.0 25.8 27.9 16.2 11.1 74.8 21.0 20.4 42.5 11.5 47.6 77.6 9.5 17.3 28.7 16.1 14.8 21.2 58.8 42.8 8.2 15.0 21.6 67.6 60.1 34.0 14.7 61.4 53.7 23.8 59.6 10.6 9.9 97.0 29.2 23.8 27.1 16.8 7.6 10.2 23.9 16.0 24.5 21.9 22.9 31.0 18.5 16.1 19.9 35.2 36.6 15.7 50.8 18.9 46.1 21.0 20.8 20.4 9.3 17.5 16.3 17.8 9.3 16.0 15.5 27.9 16.1 22.7 11.9 20.1 21.7 16.0 18.4 5.5 24.7 18.2 11.7 10.4 9.1 10.1 6.6 13.2 16.3 5.5 3.2 5.5 3.3 5.2 9.1 8.0 11.5 9.6 10.2 8.4 7.1 2.6 4.3 7.7 5.5 6.2 17.3 8.5 13.2 11.7 13.7 115.4 18.8 4.4 6.0 4.8 8.8 14.8 13.6 11.7 6.6 12.8 4.7 5.1 7.6 6.8 4.7 9.9 18.5 11.2 9.2 6.1 5.1 2.5 36.6 7.8 7.6 7.2 3.7 6.1 10.0 11.3 2.5 4.9 10.1 5.1 4.9 13.3 7.3 10.5 8.0 26.2 10.9 6.6 4.9 6.3 41.8 8.3 11.9 13.8 7.7 10.9 8.2 11.8 7.8 KATNIP "JBTS26, KIAA0556" ENSG00000047578 "Katanin interacting protein" O60303 16 27550133-27780369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 2.7;Cardiomyocytes: 4.5;Cytotrophoblasts: 3.0;dendritic cells: 1.4;Extravillous trophoblasts: 2.6;Hofbauer cells: 2.6;Syncytiotrophoblasts: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 14.3;eosinophil: 3.6;neutrophil: 9.9;NK-cell: 5.0" "Group enriched" "Detected in all" 5 "granulocytes: 14.3;NK-cells: 5.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035089, HPA035090" Enhanced Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Plasma membrane" "HPA035089: AB_10671509, HPA035090: AB_10601129" "unprognostic (1.81e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-1)" "unprognostic (3.65e-3)" "unprognostic (7.76e-2)" "prognostic favorable (3.00e-4)" "unprognostic (2.72e-2)" "unprognostic (3.58e-2)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (2.94e-1)" "unprognostic (2.12e-1)" "unprognostic (1.47e-3)" "unprognostic (2.98e-1)" "unprognostic (2.11e-1)" "unprognostic (1.50e-3)" "unprognostic (1.45e-1)" 4.4 4.8 5.2 4.7 5.9 6.7 5.4 3.9 6.9 6.3 22.7 6.5 4.8 6.3 6.2 9.7 29.7 5.1 5.4 5.4 4.1 7.8 4.0 6.3 4.4 6.7 7.8 5.1 9.0 7.7 11.5 4.4 4.9 8.8 7.2 31.3 7.9 5.7 3.3 8.9 6.0 5.5 4.9 6.2 9.3 9.9 6.3 5.6 15.9 1.7 4.0 5.3 5.8 6.6 6.7 13.5 7.5 7.0 11.1 10.1 12.4 8.9 9.6 7.7 10.4 12.0 10.9 5.7 12.4 12.8 15.0 11.0 9.7 11.5 15.4 26.5 6.7 4.5 14.9 7.0 6.6 6.1 11.0 10.8 9.9 17.1 18.2 10.0 15.5 6.3 7.3 4.7 11.1 15.3 6.7 7.5 4.6 8.6 5.5 9.6 9.1 6.2 14.5 9.2 9.5 6.1 8.9 7.9 5.0 10.3 17.8 5.3 13.5 9.8 6.2 7.7 7.9 6.3 5.7 6.4 11.3 5.9 8.9 14.3 1.8 3.6 0.7 1.2 0.7 0.8 0.4 1.2 1.2 1.1 1.6 0.3 9.9 5.0 0.4 1.4 1.6 0.3 5.2 5.9 3.9 6.9 5.4 4.1 6.7 7.8 4.9 4.9 6.3 6.6 2.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 3.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.4 0.0 0.0 0.0 KCNA4 "HK1, HPCN2, KCNA4L, Kv1.4" ENSG00000182255 "Potassium voltage-gated channel subfamily A member 4" P22459 11 30009730-30017030 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cataract, Disease variant, Dystonia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 6.1;brain: 20.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.7;Excitatory neurons: 8.2;Horizontal cells: 13.5;Muller glia cells: 6.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 20.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB001977, HPA016422" Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 62: Horizontal cells - Visual perception" "CAB001977: , HPA016422: AB_1855574" "unprognostic (1.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.73e-2)" "unprognostic (1.00e-1)" "unprognostic (4.09e-3)" "unprognostic (2.24e-1)" "unprognostic (1.15e-2)" "unprognostic (6.71e-2)" "unprognostic (1.17e-1)" 1.5 6.1 4.7 0.0 20.0 0.0 0.1 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 2.2 4.7 4.4 0.2 0.0 0.7 0.0 1.6 1.7 0.0 0.0 0.0 1.3 0.2 1.3 0.0 0.0 1.9 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 20.0 0.0 6.5 4.7 4.4 1.6 1.7 1.3 0.1 6.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 8.2 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 13.5 2.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.4 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNH1 "eag, eag1, h-eag, hEAG, Kv10.1" ENSG00000143473 "Potassium voltage-gated channel subfamily H member 1" O95259 1 210676823-211134165 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 533.5;Inhibitory neurons: 261.0;Oligodendrocytes: 116.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 6.2;RH-30: 10.1;RPTEC TERT1: 6.0;SH-SY5Y: 12.9;SK-MEL-30: 12.9;T-47d: 9.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 34.0;cerebellum: 19.1;cerebral cortex: 23.9;hippocampal formation: 17.9;olfactory bulb: 8.9" "HPA014551, HPA019445, HPA076421" Enhanced Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA014551: AB_2669038, HPA019445: AB_1852118, HPA076421: " "unprognostic (9.12e-2)" "unprognostic (4.82e-3)" "unprognostic (2.63e-1)" "unprognostic (6.70e-2)" "unprognostic (3.56e-1)" "unprognostic (3.63e-2)" "unprognostic (1.73e-1)" "unprognostic (9.36e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.77e-2)" "unprognostic (1.42e-3)" "unprognostic (1.17e-1)" "unprognostic (8.89e-2)" "unprognostic (1.36e-1)" "unprognostic (9.70e-2)" 0.2 0.9 6.8 0.4 9.2 0.0 0.2 9.5 17.9 0.7 2.7 0.5 0.3 0.4 0.2 0.1 0.6 0.2 0.0 11.2 5.3 0.1 0.1 0.0 0.0 4.8 4.4 0.1 0.2 0.0 0.7 0.3 4.0 0.5 0.3 0.3 0.1 0.1 0.2 0.1 0.8 0.2 4.0 0.0 0.5 1.5 4.9 0.2 0.1 0.6 0.0 0.2 0.4 8.3 0.0 2.1 0.4 0.1 0.0 0.1 0.1 1.0 0.2 2.1 2.4 0.0 0.0 0.0 0.0 1.4 2.4 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 10.1 0.0 6.0 0.0 0.4 12.9 2.4 0.2 12.9 1.7 9.2 0.0 0.0 1.6 0.2 2.0 1.2 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.8 9.2 9.5 17.9 11.2 5.3 4.8 4.4 4.0 4.0 4.9 8.3 0.2 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 11.2 0.2 2.8 0.1 0.0 0.0 533.5 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 261.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 7.5 0.0 0.0 0.0 19.1 116.6 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNJ2 "IRK1, Kir2.1, LQT7" ENSG00000123700 "Potassium inwardly rectifying channel subfamily J member 2" P63252 17 70168673-70180044 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Atrial fibrillation, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 42.9;parathyroid gland: 36.0" "Group enriched" "Detected in many" 4 "Horizontal cells: 240.6;Oligodendrocytes: 164.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 30.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 30.4" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 8.9;HUVEC TERT2: 6.3;REH: 7.5;RH-30: 29.2;U-138 MG: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029109 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 62: Horizontal cells - Visual perception" "HPA029109: AB_10602913" "unprognostic (1.32e-1)" "unprognostic (1.24e-1)" "unprognostic (1.18e-1)" "unprognostic (6.22e-2)" "unprognostic (3.50e-1)" "unprognostic (6.36e-3)" "unprognostic (1.22e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-1)" "unprognostic (1.62e-1)" "unprognostic (3.64e-2)" "unprognostic (1.03e-1)" "unprognostic (1.74e-3)" "unprognostic (6.15e-3)" "unprognostic (9.60e-3)" "unprognostic (4.89e-2)" "unprognostic (5.49e-3)" 1.9 0.8 7.2 5.1 19.5 1.9 4.9 13.4 13.1 0.9 0.0 3.9 0.9 0.9 0.6 2.9 6.6 1.4 9.8 5.9 11.8 1.0 1.3 2.1 1.3 18.6 16.2 0.7 0.4 36.0 0.6 6.3 18.2 1.8 3.2 7.6 1.3 1.8 9.7 4.7 1.4 1.0 10.5 7.3 0.8 0.3 14.5 1.8 1.2 8.4 1.5 1.9 1.8 42.9 0.0 0.9 1.8 0.0 1.9 0.5 0.0 0.6 4.5 0.1 0.1 0.0 0.0 0.0 0.4 0.5 1.2 0.5 0.1 0.3 0.1 0.0 0.2 0.0 0.6 0.0 5.4 0.0 0.0 2.0 0.1 2.8 0.3 8.9 6.3 0.0 0.0 0.0 1.9 0.0 0.7 0.0 0.2 0.8 0.2 7.5 29.2 0.0 0.7 0.0 0.4 0.8 0.5 0.1 0.0 3.5 0.3 0.5 0.1 10.6 0.1 0.1 2.4 0.0 0.0 0.1 2.3 0.0 1.5 4.2 3.5 5.6 0.0 6.9 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 30.4 0.0 7.3 0.2 0.0 0.8 7.2 19.5 13.4 13.1 5.9 11.8 18.6 16.2 18.2 10.5 14.5 42.9 12.0 0.0 3.2 0.0 0.6 8.2 4.1 4.9 16.5 43.5 5.8 9.3 19.3 0.0 1.9 1.8 0.0 0.5 0.1 13.5 0.0 0.1 0.3 2.3 0.2 16.0 10.7 0.4 3.8 0.0 0.4 1.7 4.1 1.6 0.0 0.1 3.3 0.1 6.8 240.6 16.2 2.7 0.0 36.9 7.4 0.0 1.5 7.8 3.6 2.8 8.2 5.8 0.0 1.5 164.7 0.0 12.3 1.2 0.0 2.2 0.9 0.1 4.9 5.2 0.0 3.9 2.6 0.1 0.9 6.9 3.3 1.4 0.8 0.2 8.5 0.3 KCNK9 "K2p9.1, TASK-3, TASK3" ENSG00000169427 "Potassium two pore domain channel subfamily K member 9" Q9NPC2 8 139600838-139704109 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 7.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 16.0;Inhibitory neurons: 8.0;Late spermatids: 9.7" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 4 "cerebellum: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA075842 Approved "Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA075842: " "unprognostic (1.84e-2)" "unprognostic (2.57e-1)" "unprognostic (1.58e-1)" "unprognostic (8.96e-8)" "unprognostic (1.91e-1)" "unprognostic (8.17e-3)" "unprognostic (2.19e-3)" "unprognostic (1.65e-1)" "unprognostic (3.87e-1)" "unprognostic (1.69e-1)" "unprognostic (1.00e-2)" "unprognostic (3.21e-1)" "unprognostic (5.12e-6)" "unprognostic (2.94e-2)" "unprognostic (1.64e-1)" "unprognostic (9.99e-3)" "unprognostic (1.76e-1)" 0.0 1.6 0.0 0.1 0.0 0.0 0.0 7.8 1.9 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.7 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 1.9 0.2 0.1 0.8 0.3 0.9 0.0 0.4 0.3 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 0.1 1.9 0.3 2.1 0.0 0.0 0.0 0.0 0.0 16.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNN3 "hSK3, KCa2.3, SKCA3" ENSG00000143603 "Potassium calcium-activated channel subfamily N member 3" Q9UGI6 1 154697455-154870281 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 33.1" "Group enriched" "Detected in many" 4 "Astrocytes: 168.8;Skeletal myocytes: 121.5" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.7;memory B-cell: 2.6" "Group enriched" "Detected in many" 11 "B-cells: 2.6;granulocytes: 4.7;monocytes: 1.4" "Cell line enhanced" "Detected in some" "Daudi: 39.3;HMC-1: 26.1;Karpas-707: 65.5;RPMI-8226: 18.7;U-266/70: 62.3;U-698: 21.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057127 Enhanced Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA057127: AB_2683345" "unprognostic (2.09e-1)" "unprognostic (2.91e-2)" "unprognostic (3.41e-2)" "unprognostic (1.04e-1)" "unprognostic (7.22e-2)" "unprognostic (4.06e-2)" "unprognostic (2.19e-2)" "unprognostic (2.03e-1)" "unprognostic (3.43e-2)" "unprognostic (9.51e-2)" "unprognostic (4.07e-3)" "unprognostic (4.89e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (1.71e-2)" "unprognostic (1.54e-1)" "unprognostic (6.93e-2)" "unprognostic (1.80e-2)" 0.9 1.1 24.9 3.9 24.2 0.3 0.7 15.1 12.8 2.7 0.0 7.4 3.0 4.9 0.6 1.7 5.7 1.5 2.1 16.9 18.5 2.1 0.2 1.5 3.5 14.4 33.1 0.8 0.3 1.1 1.2 0.0 16.5 1.6 2.4 0.3 1.3 1.2 6.1 0.3 2.2 6.0 12.9 3.5 2.4 0.5 25.7 1.0 1.9 5.3 5.5 3.1 1.6 11.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 39.3 3.1 0.0 0.1 0.1 0.9 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 26.1 0.5 0.0 0.3 0.0 0.1 0.8 0.1 0.0 65.5 0.6 0.1 0.2 0.0 0.8 0.0 2.5 0.0 16.2 18.7 0.0 0.0 0.8 0.4 0.0 0.1 0.0 0.2 0.0 0.0 1.2 1.1 0.0 0.0 0.0 62.3 8.8 21.4 0.6 0.0 6.2 4.7 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 24.9 24.2 15.1 12.8 16.9 18.5 14.4 33.1 16.5 12.9 25.7 11.0 8.7 12.8 2.7 168.8 3.9 1.3 0.6 0.7 0.6 0.5 0.1 0.0 3.4 0.0 2.1 0.0 2.1 0.1 0.0 0.0 3.9 0.2 3.4 26.6 0.6 25.9 4.2 0.0 18.2 0.2 0.0 16.3 0.0 5.8 0.0 2.0 13.9 0.3 0.4 0.0 13.6 0.0 4.1 0.0 3.0 7.7 0.3 0.9 0.0 11.2 0.0 2.2 0.0 12.1 5.0 0.0 2.2 0.0 30.9 0.5 0.0 0.3 18.3 0.4 0.0 121.5 1.3 0.7 0.2 0.8 1.7 0.0 0.5 22.5 0.0 0.7 KCNQ1 "JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1" ENSG00000053918 "Potassium voltage-gated channel subfamily Q member 1" P51787 11 2444684-2849105 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Deafness, Diabetes mellitus, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 197.1;stomach 1: 98.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 47.6;Microglial cells: 71.2;Undifferentiated cells: 57.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 33.4;OE19: 41.4;RPMI-8226: 23.2;U-266/70: 11.5;U-937: 13.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB018656, HPA048553, HPA071107" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "Plasma membrane" "CAB018656: AB_2131551, HPA048553: AB_2680438, HPA071107: " "unprognostic (6.02e-2)" "unprognostic (2.48e-1)" "unprognostic (6.39e-3)" "unprognostic (4.38e-1)" "unprognostic (1.86e-1)" "unprognostic (1.83e-1)" "unprognostic (3.46e-2)" "unprognostic (7.36e-2)" "unprognostic (8.07e-2)" "unprognostic (8.81e-2)" "unprognostic (1.58e-1)" "unprognostic (5.39e-2)" "unprognostic (2.46e-3)" "prognostic favorable (9.85e-4)" "unprognostic (3.99e-2)" "unprognostic (4.19e-2)" "unprognostic (5.27e-2)" 5.4 197.1 2.1 9.0 2.4 14.2 3.0 2.4 2.6 16.5 5.7 22.6 47.8 2.9 14.1 2.9 8.9 19.5 28.4 2.6 2.6 25.3 1.8 15.9 5.0 4.1 3.1 1.4 61.2 21.4 5.5 7.6 3.9 6.1 15.2 0.7 20.0 50.2 1.0 1.2 39.7 3.1 4.0 8.2 98.9 1.6 4.2 3.6 71.6 1.6 2.9 14.7 1.6 4.4 0.0 0.1 0.0 5.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 2.6 1.9 5.2 0.0 0.4 0.1 0.7 0.0 0.0 0.4 1.3 0.0 3.7 0.4 0.3 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.7 0.0 0.7 1.3 41.4 0.2 0.1 0.0 23.2 8.0 2.7 0.7 5.6 0.7 0.0 0.0 0.5 0.2 10.3 0.0 0.0 0.3 0.2 0.0 11.5 0.0 0.0 0.0 13.4 0.0 0.7 3.1 3.1 0.0 1.8 0.0 0.8 0.4 0.1 3.8 0.3 1.0 1.2 3.3 0.0 2.8 1.3 0.3 1.0 2.1 2.4 2.4 2.6 2.6 2.6 4.1 3.1 3.9 4.0 4.2 4.4 7.1 3.2 12.9 0.3 8.4 0.6 8.0 4.2 0.0 1.7 6.1 1.8 18.6 14.3 7.1 29.5 0.0 1.1 0.3 34.0 15.6 23.2 2.0 3.3 0.4 6.3 6.6 0.4 13.7 21.7 1.4 1.0 23.4 4.9 19.7 47.6 9.3 1.1 17.3 0.0 20.0 26.1 8.2 25.4 15.9 0.9 0.3 19.6 1.8 71.2 11.0 0.5 1.0 43.7 34.9 15.3 20.2 0.0 6.4 5.2 30.9 2.0 4.4 0.5 6.6 0.4 1.7 0.2 0.2 0.1 1.0 2.1 4.0 16.6 57.8 20.4 KDF1 "C1orf172, FLJ34633, RP11-344H11.3" ENSG00000175707 "Keratinocyte differentiation factor 1" Q8NAX2 1 26949562-26960468 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.6;Ductal cells: 29.4;Syncytiotrophoblasts: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 36 "B-cells: 3.4;T-cells: 6.2" "Cell line enhanced" "Detected in some" "A-431: 24.9;BEWO: 20.8;CAPAN-2: 22.7;HaCaT: 21.4;HBEC3-KT: 30.3;hTCEpi: 38.5;OE19: 39.3;SK-BR-3: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA028634, HPA028639" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Cytosol "HPA028634: , HPA028639: AB_10599191" "unprognostic (2.58e-1)" "unprognostic (1.23e-1)" "unprognostic (6.46e-2)" "unprognostic (1.50e-2)" "unprognostic (1.15e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (8.45e-2)" "unprognostic (9.09e-2)" "unprognostic (9.01e-2)" "unprognostic (2.73e-1)" "unprognostic (3.91e-1)" "prognostic favorable (3.04e-13)" "unprognostic (1.38e-3)" "unprognostic (7.83e-2)" "unprognostic (8.03e-2)" "prognostic favorable (4.40e-4)" 0.1 1.1 0.4 1.3 0.3 0.1 10.3 1.6 1.3 4.0 0.3 8.9 12.4 0.9 19.7 20.2 7.4 2.9 0.4 0.4 0.2 11.0 4.7 4.4 0.8 0.3 0.3 0.1 16.2 12.5 10.4 3.9 0.4 7.2 7.1 1.3 12.8 4.6 0.0 17.7 10.5 0.3 0.2 0.6 10.6 2.6 0.3 2.3 10.0 0.0 3.4 4.8 8.3 0.7 24.9 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 12.1 22.7 0.0 0.9 0.0 0.0 21.4 0.0 30.3 0.0 0.1 0.4 0.0 0.0 4.4 0.3 0.0 0.0 0.1 38.5 0.0 3.1 0.0 0.0 0.0 1.4 0.0 0.0 14.7 0.0 0.1 1.7 39.3 0.1 0.0 0.0 3.7 5.5 11.7 14.9 0.0 0.2 25.2 0.1 2.7 16.1 0.4 0.2 0.0 0.0 0.0 0.0 2.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 3.2 2.5 4.3 3.0 0.1 3.4 6.2 3.8 0.0 0.0 0.0 0.0 0.2 1.7 0.4 0.3 1.6 1.3 0.4 0.2 0.3 0.3 0.4 0.2 0.3 0.7 0.2 12.8 8.8 0.0 0.8 0.0 14.3 0.0 10.8 0.6 15.1 16.3 0.3 12.8 2.5 14.7 0.0 32.6 1.5 17.2 25.4 29.4 0.4 7.3 0.8 0.7 7.8 0.0 0.2 23.2 26.5 0.6 13.7 8.0 0.0 0.1 0.0 4.4 2.7 0.0 0.1 13.1 0.0 0.3 0.0 0.1 0.3 0.1 0.0 0.0 0.2 1.1 0.0 0.0 0.1 21.8 25.2 0.0 0.4 16.8 26.2 10.1 5.1 2.5 0.0 0.0 0.3 6.3 7.5 14.4 0.0 29.7 1.2 0.0 16.9 19.0 KDM1A "AOF2, BHC110, KDM1, KIAA0601, LSD1" ENSG00000004487 "Lysine demethylase 1A" O60341 1 23019443-23083689 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Oxidoreductase, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005884, HPA053660" Supported Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 7700 "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Cytosol "CAB005884: AB_443964, HPA053660: AB_2682220" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "prognostic favorable (6.31e-4)" "unprognostic (1.50e-1)" "unprognostic (6.83e-2)" "unprognostic (3.95e-2)" "prognostic unfavorable (4.47e-12)" "unprognostic (1.80e-2)" "unprognostic (1.99e-2)" "unprognostic (9.41e-2)" "unprognostic (3.34e-3)" "unprognostic (2.13e-1)" "unprognostic (2.61e-1)" "unprognostic (1.41e-1)" "unprognostic (3.73e-2)" "unprognostic (7.74e-2)" "unprognostic (1.39e-1)" 25.7 30.8 24.7 23.5 25.8 48.1 30.6 26.5 27.0 33.1 20.4 31.6 26.4 36.0 46.9 35.0 34.2 25.3 26.1 25.3 28.2 24.7 22.3 24.5 34.7 19.8 22.0 41.4 36.2 51.2 41.5 31.5 21.0 32.2 33.8 30.9 36.6 29.4 47.3 38.2 29.2 30.1 21.2 25.2 29.3 86.9 27.4 55.8 28.5 34.0 37.2 34.6 31.5 21.8 128.1 64.7 180.8 160.7 47.0 59.5 128.4 53.1 66.4 106.0 93.7 61.2 120.5 94.5 74.1 87.6 53.7 139.5 169.5 101.0 133.3 86.3 102.7 133.0 105.7 150.6 59.6 103.7 56.0 55.6 71.4 112.8 78.9 93.0 134.1 171.7 148.0 43.4 76.3 75.9 227.3 79.2 118.3 70.8 93.0 214.7 119.1 64.1 89.0 81.0 225.0 169.9 239.4 62.4 80.2 126.1 62.7 76.2 109.5 47.0 78.4 88.1 73.6 55.6 47.1 109.3 49.2 120.4 68.3 2.0 2.5 4.3 4.1 4.3 3.4 7.4 3.5 3.8 3.1 2.1 4.5 4.9 0.2 3.0 5.5 6.8 4.4 1.4 24.7 25.8 26.5 27.0 25.3 28.2 19.8 22.0 21.0 21.2 27.4 21.8 18.7 19.2 29.1 33.6 15.9 18.6 27.1 19.9 33.0 27.5 20.4 22.1 24.4 11.5 19.0 23.9 27.1 31.6 18.1 15.7 17.6 35.4 43.5 45.9 49.3 20.4 22.8 29.7 51.1 24.7 57.2 24.8 23.4 44.4 12.0 49.5 16.8 17.2 15.0 15.2 51.2 24.9 22.4 15.1 19.7 20.3 21.5 20.2 12.4 30.0 28.1 19.3 12.3 50.3 30.4 28.1 13.5 23.0 28.9 26.3 17.2 15.7 29.5 19.8 0.0 22.2 25.0 131.8 67.1 36.1 12.8 16.6 15.4 34.3 27.6 20.5 KDM6A UTX ENSG00000147050 "Lysine demethylase 6A" O15550 X 44873188-45112779 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 116.2;Oligodendrocyte precursor cells: 118.1;Oligodendrocytes: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000568, HPA001165, HPA002111" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.45e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.65e-2)" "unprognostic (2.58e-3)" "unprognostic (8.22e-3)" "unprognostic (3.23e-1)" "unprognostic (2.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" "unprognostic (2.24e-2)" "unprognostic (5.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.16e-2)" 9.6 8.0 6.7 4.5 7.6 19.4 10.6 7.2 10.6 15.7 6.5 9.1 6.2 14.0 5.1 11.1 14.0 3.4 6.6 6.8 6.9 6.8 10.4 10.8 8.0 7.3 6.8 17.2 10.8 6.4 8.6 3.9 7.3 7.7 4.1 3.8 10.5 3.1 10.4 18.4 13.0 4.1 7.1 14.1 12.5 12.2 7.0 12.9 9.4 6.1 5.3 9.8 15.2 9.9 7.3 5.8 7.0 9.3 5.0 6.8 15.7 4.9 4.2 4.0 4.1 10.4 5.2 4.6 3.2 3.5 10.1 13.9 6.5 5.4 3.9 7.6 10.8 2.4 4.5 5.2 3.7 2.6 13.2 2.6 6.4 8.2 6.6 5.1 4.2 5.3 6.4 10.1 2.4 6.0 6.9 13.6 6.8 4.2 7.4 6.4 7.1 1.4 3.8 9.2 6.2 4.4 18.2 6.8 10.7 14.1 8.5 0.0 3.0 5.4 5.2 5.2 3.6 5.5 8.8 5.6 4.0 3.3 3.3 7.3 1.7 1.5 1.9 3.5 2.1 1.9 2.5 2.8 3.1 1.2 2.5 2.4 2.8 2.8 3.0 1.7 2.2 2.0 6.7 7.6 7.2 10.6 6.8 6.9 7.3 6.8 7.3 7.1 7.0 9.9 23.2 6.4 10.6 92.1 26.0 26.1 14.3 9.4 38.1 7.7 16.8 12.1 12.8 12.8 10.9 7.3 14.6 4.5 26.1 24.6 0.0 8.4 1.5 26.4 25.5 13.1 13.1 16.8 88.3 7.5 7.9 14.2 23.0 39.7 2.5 27.3 6.4 17.6 7.0 25.2 74.0 14.0 6.1 9.1 13.8 2.0 6.5 19.9 10.6 116.2 12.6 6.8 6.2 118.1 264.6 9.1 17.4 7.2 31.4 14.2 22.6 3.7 8.9 9.7 6.6 20.9 17.0 14.1 12.5 29.3 26.3 10.9 27.4 10.6 13.1 17.1 KDSR "DHSR, FVT1, SDR35C1" ENSG00000119537 "3-ketodihydrosphingosine reductase" Q06136 18 63327726-63367228 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Palmoplantar keratoderma, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 90.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003673, HPA044884" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "CAB003673: AB_425440, HPA044884: AB_2679131" "unprognostic (4.44e-2)" "unprognostic (8.57e-2)" "unprognostic (2.52e-2)" "unprognostic (4.56e-2)" "unprognostic (5.88e-3)" "unprognostic (7.50e-3)" "unprognostic (1.80e-2)" "unprognostic (2.66e-1)" "unprognostic (2.97e-1)" "unprognostic (1.97e-1)" "unprognostic (2.70e-2)" "unprognostic (6.81e-2)" "prognostic favorable (9.53e-6)" "unprognostic (3.32e-2)" "unprognostic (5.77e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-3)" 32.3 22.4 12.8 8.1 19.9 4.8 25.4 19.5 16.7 26.9 12.3 24.6 7.0 22.7 20.8 22.4 18.9 12.6 20.7 12.7 16.4 20.1 36.7 21.5 7.0 20.6 17.7 21.3 15.7 13.1 12.1 8.5 20.0 16.3 7.4 7.0 22.8 11.6 16.7 44.5 15.1 13.3 17.6 8.4 16.4 6.1 16.6 7.1 17.2 8.9 6.8 23.9 23.4 22.4 14.9 6.5 6.7 7.5 52.6 39.0 13.0 48.8 29.7 10.5 13.9 2.7 10.0 15.1 20.3 19.1 17.4 64.6 8.7 27.3 12.8 28.6 14.5 11.6 8.7 3.4 40.1 22.0 7.8 37.4 50.7 16.8 47.9 19.3 10.5 9.9 9.5 21.0 28.1 6.2 23.6 9.7 8.0 3.7 23.5 15.5 19.7 21.9 29.0 9.6 8.5 16.4 23.4 11.3 21.9 8.8 6.1 12.1 24.9 44.0 10.6 14.8 21.3 90.4 44.9 8.7 33.2 13.0 13.4 0.1 5.2 0.5 6.5 8.1 26.6 5.7 13.6 10.2 8.0 4.7 9.3 6.1 1.3 14.2 3.9 3.8 19.1 5.3 12.8 19.9 19.5 16.7 12.7 16.4 20.6 17.7 20.0 17.6 16.6 22.4 53.1 35.3 49.1 21.9 30.1 158.6 131.7 47.0 122.3 37.4 63.4 63.6 27.7 62.9 43.5 38.6 27.1 58.8 15.6 34.6 15.6 50.7 1.0 43.9 53.0 48.1 20.4 17.4 19.1 36.7 70.4 82.0 26.5 64.9 26.0 52.3 51.8 88.3 36.4 40.4 24.2 31.8 42.7 32.2 47.7 6.5 71.1 39.9 56.9 14.0 31.5 56.5 13.4 21.6 57.0 47.4 44.6 70.7 24.5 104.3 43.4 39.6 41.2 41.1 32.9 73.7 48.4 1.3 5.2 89.7 143.1 91.4 37.7 51.1 40.3 94.7 KERA "CNA2, SLRR2B" ENSG00000139330 Keratocan O60938 12 91050491-91058024 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Fibroblasts: 2.0" "Cancer enhanced" "Detected in some" "testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "amygdala: 4.1;basal ganglia: 5.6;cerebral cortex: 6.2;hippocampal formation: 5.6" HPA039321 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 50: Fibroblasts - ECM organization" "HPA039321: AB_10795248" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.47e-1)" "unprognostic (3.70e-1)" "unprognostic (4.76e-3)" "unprognostic (3.65e-1)" "unprognostic (6.08e-2)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (5.96e-2)" "unprognostic (4.93e-3)" "unprognostic (2.06e-2)" "unprognostic (2.53e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.1 0.1 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 KIAA0586 "JBTS23, Talpid3" ENSG00000100578 KIAA0586 Q9BVV6 14 58427385-58551297 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 81.3;Early spermatids: 142.0;Late spermatids: 108.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000846, HPA050249" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA000846: AB_2234167, HPA050249: " "unprognostic (1.90e-1)" "unprognostic (7.85e-2)" "unprognostic (2.98e-2)" "unprognostic (6.88e-2)" "unprognostic (4.99e-2)" "unprognostic (1.76e-3)" "unprognostic (4.82e-3)" "unprognostic (1.13e-1)" "unprognostic (2.80e-1)" "unprognostic (2.39e-1)" "unprognostic (2.67e-2)" "unprognostic (5.65e-2)" "prognostic favorable (7.20e-4)" "unprognostic (8.10e-3)" "unprognostic (1.77e-1)" "unprognostic (3.41e-1)" "unprognostic (1.13e-1)" 5.0 5.1 4.6 4.8 4.9 5.4 5.7 6.0 7.1 5.1 4.5 4.9 3.3 4.3 6.2 5.0 4.3 4.9 4.7 4.3 4.9 4.0 6.5 4.2 7.4 4.9 5.1 6.0 4.0 6.1 7.1 3.7 5.0 5.1 6.0 7.9 4.2 4.6 5.8 5.2 4.4 6.3 4.7 5.4 3.9 16.4 4.7 12.4 4.9 6.1 7.1 5.6 4.8 6.5 21.1 14.0 20.2 9.7 16.4 15.6 8.7 17.3 16.3 15.1 15.7 6.0 11.3 23.4 11.4 14.8 6.2 12.3 19.1 10.9 24.8 16.8 6.9 17.9 11.1 18.2 11.2 27.6 15.3 10.5 4.6 11.2 17.7 7.2 19.9 22.3 18.0 12.4 28.4 13.5 16.9 11.4 8.7 10.7 22.8 20.5 23.5 14.6 10.9 8.8 11.1 8.4 18.4 12.3 8.9 10.8 14.7 14.4 18.8 23.4 18.4 12.9 14.5 7.4 9.5 19.0 16.2 21.8 13.7 13.2 2.0 5.0 7.0 2.1 5.6 6.3 6.6 5.3 2.6 6.8 8.5 6.1 2.0 9.7 3.2 3.3 7.1 2.6 4.6 4.9 6.0 7.1 4.3 4.9 4.9 5.1 5.0 4.7 4.7 6.5 17.9 12.8 14.5 29.4 20.9 3.2 6.1 6.2 12.5 30.5 10.1 9.8 14.1 7.2 9.3 9.2 81.3 7.5 20.1 5.9 5.9 6.5 142.0 18.5 19.6 13.9 10.7 22.1 52.0 5.2 8.4 14.5 16.8 11.0 21.5 15.2 9.3 4.7 9.5 32.0 56.7 8.5 10.2 7.9 2.8 108.1 10.2 10.8 8.8 27.2 10.6 17.0 14.4 47.3 73.9 5.9 3.0 12.0 20.6 4.3 4.3 7.7 20.0 51.0 0.0 19.7 12.3 61.6 23.9 12.4 4.5 4.8 24.4 15.7 7.3 3.3 KIAA0753 "MNR, OFIP" ENSG00000198920 KIAA0753 Q2KHM9 17 6578147-6640711 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Ciliopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 90.9;Excitatory neurons: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA023057, HPA023494" Enhanced Approved Centrosome,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Centrosome, Cytosol" "HPA023057: AB_1852338, HPA023494: AB_1852339" "unprognostic (3.72e-2)" "unprognostic (5.91e-2)" "unprognostic (1.60e-2)" "unprognostic (2.93e-2)" "unprognostic (5.17e-2)" "unprognostic (1.47e-1)" "unprognostic (4.19e-3)" "unprognostic (1.47e-1)" "unprognostic (3.01e-3)" "unprognostic (1.82e-1)" "unprognostic (6.10e-3)" "unprognostic (1.47e-2)" "unprognostic (9.57e-2)" "unprognostic (1.37e-1)" "unprognostic (2.70e-1)" "unprognostic (1.55e-1)" "unprognostic (1.77e-3)" 4.9 5.7 6.8 4.6 6.8 3.5 7.3 3.8 7.3 8.4 10.5 7.1 3.5 8.5 11.0 7.1 10.1 5.2 4.1 7.2 6.6 8.7 3.7 5.3 5.0 4.3 4.9 10.1 5.6 14.0 8.8 5.3 3.6 7.7 6.9 10.8 5.7 8.3 2.1 5.7 5.4 8.4 3.4 7.6 6.5 16.6 6.0 8.5 9.0 2.7 5.1 6.4 6.4 5.5 19.9 16.1 19.4 13.2 7.2 11.9 7.7 10.5 10.0 15.1 14.0 11.1 4.8 7.9 7.1 10.4 9.9 18.4 17.8 10.1 23.9 8.1 15.1 4.3 14.8 8.7 12.0 6.9 9.3 7.1 12.9 13.7 13.0 15.5 11.8 9.1 9.9 1.0 12.3 5.9 7.7 6.2 11.8 9.7 8.1 11.1 6.8 2.5 13.9 12.9 7.3 12.7 13.2 3.9 8.9 12.5 6.5 4.5 11.1 13.1 6.7 7.6 16.8 1.8 2.6 2.8 9.8 4.5 10.6 0.0 0.7 0.6 0.5 0.7 0.6 0.8 0.5 0.5 0.4 0.4 0.3 0.3 1.9 0.4 0.4 0.6 0.4 0.2 6.8 6.8 3.8 7.3 7.2 6.6 4.3 4.9 3.6 3.4 6.0 5.5 5.4 6.4 12.3 25.8 3.4 3.2 2.9 2.6 4.6 3.8 5.9 5.2 3.6 7.2 8.3 0.0 16.7 2.4 2.9 5.2 0.0 4.1 90.9 13.2 9.5 5.7 7.2 3.0 46.6 3.8 1.1 6.3 9.7 5.8 1.3 12.9 3.9 2.1 2.5 10.1 29.2 3.9 4.1 3.1 0.6 15.4 4.4 3.2 0.0 25.3 2.8 2.1 2.1 27.2 14.7 3.9 4.9 3.4 5.6 3.6 2.2 2.9 29.3 12.1 0.0 5.9 5.4 15.1 7.8 5.0 2.4 1.2 3.1 9.3 4.4 2.7 KIAA0825 "C5orf36, DKFZp686F0372, MGC34713" ENSG00000185261 KIAA0825 Q8IV33 5 94152966-94618597 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 53.2;Cone photoreceptor cells: 50.1;Excitatory neurons: 171.0;Inhibitory neurons: 168.5;Microglial cells: 56.2;Oligodendrocyte precursor cells: 63.3;Oligodendrocytes: 62.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "neutrophil: 12.4" "Lineage enriched" "Detected in single" 14 "granulocytes: 12.4" "Cell line enhanced" "Detected in many" "HeLa: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038030, HPA038031" Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA038030: AB_10672735, HPA038031: AB_2675794" "unprognostic (1.26e-1)" "unprognostic (7.73e-2)" "unprognostic (1.93e-4)" "unprognostic (2.72e-3)" "unprognostic (1.41e-1)" "unprognostic (7.63e-3)" "unprognostic (4.44e-2)" "unprognostic (6.90e-2)" "unprognostic (3.37e-1)" "unprognostic (4.95e-3)" "unprognostic (2.14e-1)" "unprognostic (1.07e-1)" "unprognostic (9.02e-5)" "unprognostic (3.00e-2)" "unprognostic (8.65e-2)" "unprognostic (1.11e-3)" "unprognostic (2.09e-2)" 0.9 1.0 1.8 0.6 1.9 1.0 1.1 1.9 1.8 1.0 1.0 0.6 0.4 1.4 1.3 1.1 2.6 1.2 0.9 1.6 1.6 1.5 0.9 1.0 0.7 2.3 2.4 1.6 0.9 1.4 1.0 0.9 1.7 1.0 0.7 3.4 0.6 0.8 0.4 0.6 0.6 0.9 1.2 0.8 0.6 3.0 1.8 0.7 1.9 0.6 0.5 1.0 0.5 1.3 0.5 0.2 0.6 1.6 2.1 2.7 0.2 1.6 1.4 1.0 1.5 0.0 1.1 0.2 1.7 0.6 1.1 0.8 0.3 1.1 1.3 0.0 0.3 0.2 9.9 0.2 1.5 0.3 0.1 1.6 1.1 1.3 0.3 1.3 1.0 0.9 0.2 0.0 1.9 1.1 0.7 0.7 0.9 0.3 0.2 0.8 0.1 0.1 2.0 0.5 1.0 1.3 1.6 0.1 0.3 1.0 0.8 1.2 1.0 0.9 0.2 1.3 0.6 0.4 0.4 0.0 2.0 0.5 0.8 0.0 0.6 0.0 0.4 0.2 0.2 0.8 0.4 0.6 0.6 0.4 0.2 0.3 12.4 0.6 0.4 0.6 0.2 0.2 1.8 1.9 1.9 1.8 1.6 1.6 2.3 2.4 1.7 1.2 1.8 1.3 3.0 6.4 4.1 53.2 1.5 1.3 1.4 1.4 1.2 9.8 2.8 1.7 2.3 2.8 2.1 1.8 50.1 1.0 2.7 0.8 0.0 1.1 10.4 20.3 6.5 1.6 0.0 1.3 171.0 0.6 0.6 4.6 1.5 2.3 1.3 3.7 1.4 1.8 1.0 15.2 168.5 0.6 2.0 1.0 1.6 6.0 1.2 1.7 0.0 56.2 0.7 4.6 0.0 63.3 62.7 0.8 0.2 1.5 1.7 0.6 1.0 3.3 13.1 20.5 0.0 4.4 3.0 8.7 3.9 1.2 1.1 0.3 4.3 5.8 0.6 0.7 KIAA1109 "FLJ21404, FSA, KIAA1371, Tweek" ENSG00000138688 KIAA1109 Q2LD37 4 122152331-122362758 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 245.2;Inhibitory neurons: 246.5;Oligodendrocytes: 239.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038076 Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Centrosome" "HPA038076: AB_10670652" "unprognostic (2.53e-1)" "unprognostic (2.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (2.63e-3)" "unprognostic (1.04e-1)" "unprognostic (6.62e-2)" "unprognostic (7.61e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.97e-2)" "prognostic favorable (4.33e-8)" "unprognostic (2.04e-1)" "unprognostic (3.55e-1)" "unprognostic (2.28e-2)" "unprognostic (2.29e-2)" 29.3 24.9 39.5 13.7 48.4 60.3 31.7 41.7 42.8 29.8 62.3 29.6 18.8 27.6 29.8 17.5 27.2 19.8 22.9 36.0 38.5 27.8 21.3 28.2 19.8 48.4 39.1 41.6 24.8 56.3 47.1 17.5 44.6 21.9 22.1 82.4 22.4 21.7 55.5 28.7 28.3 22.1 35.4 26.4 23.3 26.6 44.0 23.1 31.5 42.2 16.8 24.5 25.6 60.5 30.5 9.5 22.3 14.8 36.3 46.7 11.6 13.5 25.3 13.6 14.9 7.2 15.7 15.9 7.6 32.2 18.4 11.2 13.7 16.7 22.0 12.1 8.8 17.7 18.4 13.7 18.9 16.7 9.4 27.2 19.6 16.4 22.3 37.2 29.3 17.0 11.6 18.8 28.5 10.3 14.5 13.0 7.4 14.6 10.7 8.2 30.8 4.1 24.1 22.6 13.0 11.6 8.4 9.7 18.8 35.8 10.6 13.5 39.8 16.8 16.7 14.0 14.0 18.1 12.5 11.5 17.8 14.4 12.6 1.8 0.7 4.3 1.6 1.8 1.7 1.2 1.1 1.1 0.7 1.8 0.9 1.1 3.3 1.0 0.9 1.1 1.6 0.4 39.5 48.4 41.7 42.8 36.0 38.5 48.4 39.1 44.6 35.4 44.0 60.5 94.6 86.6 42.8 245.2 36.0 20.9 22.0 19.8 26.2 126.0 36.2 27.6 69.2 22.8 35.9 42.3 125.1 12.0 59.6 42.4 1.9 13.8 35.1 34.3 52.8 47.2 21.6 27.1 194.0 17.5 7.0 41.2 59.7 47.2 21.5 64.4 35.0 24.1 12.7 92.5 246.5 27.3 20.3 30.1 17.5 27.7 51.3 41.0 16.0 153.6 32.5 60.9 26.8 161.9 239.9 20.7 34.9 50.8 47.9 19.3 50.0 10.3 33.1 145.0 32.9 63.1 54.9 63.2 33.9 28.9 24.4 13.0 52.0 34.0 32.0 23.0 KIF11 "Eg5, HKSP, KNSL1, TRIP5" ENSG00000138160 "Kinesin family member 11" P52732 10 92574105-92655395 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.4;lymphoid tissue: 37.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 39.1;Granulosa cells: 20.7;Spermatocytes: 38.0;Spermatogonia: 23.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006916, HPA010093, HPA010568, CAB017617" Enhanced Supported "Mitotic spindle,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Mitotic spindle" "CAB017617: AB_2131098, HPA006916: AB_1848033, HPA010093: AB_2668281, HPA010568: AB_1848034" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (1.59e-2)" "unprognostic (3.35e-2)" "unprognostic (2.12e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (8.19e-7)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.30e-4)" "unprognostic (6.59e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.35e-3)" "unprognostic (7.23e-2)" "unprognostic (9.08e-2)" "unprognostic (2.01e-1)" 1.1 0.7 0.5 8.5 0.7 19.4 2.5 0.4 0.6 1.4 0.5 6.3 5.5 1.8 1.0 6.7 1.0 1.2 0.6 0.5 0.5 1.0 1.1 1.3 17.5 0.6 0.6 0.6 0.5 0.7 0.3 3.9 0.6 1.0 7.4 0.8 1.3 0.7 0.2 6.0 5.3 2.5 0.5 2.9 3.9 11.6 0.4 37.9 1.6 0.3 18.5 2.3 2.3 0.6 103.1 45.2 100.6 94.5 7.3 10.5 24.2 72.6 62.8 78.8 78.1 39.6 67.2 111.1 36.5 34.4 32.9 72.0 72.1 36.5 92.4 68.3 41.3 70.5 41.4 42.4 1.4 116.0 63.0 3.6 3.3 61.4 55.9 18.3 50.0 46.1 51.2 126.4 61.1 41.4 99.3 65.8 40.3 42.5 30.7 106.6 98.8 40.2 21.0 30.1 30.0 42.9 56.4 25.9 29.2 34.1 67.9 37.6 28.6 35.7 51.3 37.1 96.9 35.4 58.3 113.4 29.5 82.3 50.3 0.8 0.0 0.1 0.0 0.3 0.3 0.6 0.4 0.4 0.2 0.1 0.1 0.2 0.2 1.0 0.1 0.1 1.1 0.2 0.5 0.7 0.4 0.6 0.5 0.5 0.6 0.6 0.6 0.5 0.4 0.6 0.4 0.0 2.0 1.3 3.5 2.9 1.1 1.6 3.4 1.0 1.8 1.8 1.7 1.5 2.5 1.8 0.0 6.7 2.3 2.9 1.9 0.5 16.3 3.4 4.3 2.0 0.0 39.1 2.1 0.6 11.4 4.7 9.2 4.9 0.0 20.7 2.2 0.4 8.2 0.0 1.8 4.3 4.1 4.6 3.4 4.4 0.9 4.0 0.0 0.0 1.0 0.7 2.1 2.5 1.1 0.2 0.4 0.7 15.2 0.8 0.5 0.6 3.7 0.4 0.0 1.7 3.7 38.0 23.4 12.6 3.3 1.5 4.5 2.5 8.0 1.7 KIF14 KIAA0042 ENSG00000118193 "Kinesin family member 14" Q15058 1 200551497-200620751 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Meckel syndrome, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 27.1;Granulosa cells: 13.2;Spermatocytes: 22.8;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038061, HPA058220" Uncertain Supported "Midbody ring,Cytosol" Yes Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Midbody ring" "HPA038061: AB_10669515, HPA058220: AB_2683642" "unprognostic (1.84e-1)" "unprognostic (7.15e-2)" "unprognostic (2.00e-2)" "unprognostic (1.87e-2)" "unprognostic (2.74e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-3)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.47e-3)" "unprognostic (1.02e-1)" "unprognostic (2.54e-5)" "unprognostic (2.31e-2)" "unprognostic (0.00e+0)" "unprognostic (6.28e-3)" "unprognostic (3.31e-1)" "unprognostic (8.14e-2)" "unprognostic (7.44e-2)" 0.2 0.2 0.1 2.0 0.0 6.5 0.3 0.2 0.3 0.2 0.1 0.9 1.2 0.3 0.0 1.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.2 3.2 0.1 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.0 1.2 0.1 0.1 0.0 0.0 1.0 1.1 0.6 0.0 0.6 0.6 2.5 0.1 10.9 0.1 0.0 3.2 0.4 0.3 0.1 29.7 17.3 26.8 15.0 0.8 3.0 14.8 20.0 11.7 18.7 16.8 10.5 15.1 18.0 7.0 9.6 11.6 23.0 21.6 13.3 26.7 22.1 11.3 28.8 24.8 10.3 0.1 45.5 15.7 0.6 0.6 20.9 17.8 4.0 13.5 26.3 44.0 22.6 23.5 12.1 26.9 14.2 22.6 8.7 15.0 24.3 35.4 22.8 6.3 8.3 12.7 14.0 28.3 9.5 11.0 19.8 12.9 11.6 11.1 14.7 17.3 16.2 35.3 8.2 8.9 25.8 8.6 24.0 30.5 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.3 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 1.0 0.0 0.0 0.0 1.9 2.4 1.0 1.1 0.6 2.3 1.5 1.9 0.8 0.0 0.9 0.0 2.1 4.2 0.6 2.5 0.0 0.2 4.1 3.7 2.2 1.6 0.0 27.1 1.1 0.0 7.7 3.3 10.2 5.0 2.5 13.2 2.5 0.9 5.4 0.0 0.9 5.2 0.0 2.9 1.9 2.5 0.6 2.3 0.0 0.0 0.4 0.5 0.0 0.5 0.8 0.3 0.0 0.7 11.3 1.2 0.2 0.1 1.4 0.8 6.6 1.4 2.1 22.8 16.3 8.3 0.9 1.4 2.3 0.7 4.3 1.9 KIF22 "Kid, KNSL4, OBP-1, OBP-2" ENSG00000079616 "Kinesin family member 22" Q14807 16 29790719-29805384 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Motor protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.5;lymphoid tissue: 73.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 288.7;Hepatocytes: 565.5;Proximal tubular cells: 194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048213, HPA075670" Enhanced Supported "Nuclear speckles" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "Nuclear speckles" "HPA048213: AB_2680316, HPA075670: " "unprognostic (3.71e-2)" "prognostic favorable (3.87e-8)" "unprognostic (1.86e-1)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (6.06e-3)" "unprognostic (5.06e-3)" "unprognostic (2.70e-1)" "unprognostic (2.70e-1)" "unprognostic (4.73e-2)" "unprognostic (7.84e-2)" "unprognostic (2.10e-2)" "unprognostic (2.21e-2)" "unprognostic (3.67e-2)" "unprognostic (2.62e-1)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" 9.2 7.0 9.5 19.7 9.9 88.5 13.4 8.1 10.4 10.5 6.9 22.6 16.6 8.2 8.6 22.3 12.3 6.4 10.8 9.5 8.9 11.2 8.3 8.5 34.1 8.4 8.3 8.2 7.3 33.8 9.2 15.7 8.3 24.9 20.6 8.9 10.5 12.0 8.4 32.8 16.9 8.0 8.9 18.6 11.8 28.3 9.4 73.0 26.0 11.0 34.7 10.1 13.3 9.3 89.3 103.9 120.6 87.6 8.0 11.9 104.8 65.8 52.1 123.1 113.9 97.9 103.3 130.6 60.4 34.4 61.2 90.0 118.9 67.5 57.4 84.8 100.4 72.4 115.1 119.0 2.7 79.1 76.0 6.7 17.7 68.5 51.3 17.1 67.2 144.7 109.4 104.1 65.5 186.5 173.1 196.1 101.8 65.7 59.6 237.9 110.6 122.4 44.9 45.0 99.8 65.4 48.5 94.7 33.1 39.4 84.8 105.2 29.8 63.8 66.6 57.7 72.6 96.6 105.3 141.4 41.9 129.0 83.3 58.7 14.1 39.5 49.7 21.1 37.3 30.4 50.0 53.1 14.7 27.3 40.0 38.4 6.2 31.5 18.3 9.6 56.5 40.5 9.5 9.9 8.1 10.4 9.5 8.9 8.4 8.3 8.3 8.9 9.4 9.3 13.9 32.1 115.4 5.5 23.0 30.8 25.8 56.7 52.9 27.5 56.5 56.4 288.7 57.2 38.5 69.9 25.0 81.7 20.1 44.2 62.6 16.6 9.9 29.5 18.9 29.2 41.4 85.2 4.8 50.1 85.4 50.1 25.0 31.1 43.6 29.5 49.2 565.5 46.3 6.7 6.1 39.5 34.6 47.7 40.4 8.5 15.5 36.7 35.6 4.7 38.6 69.8 29.9 4.0 5.3 17.3 44.0 12.8 49.9 26.1 18.0 194.0 29.7 20.5 13.1 23.7 34.2 50.9 61.6 41.4 27.6 76.9 34.2 12.2 42.3 22.5 KIF2A "HK2, KIF2" ENSG00000068796 "Kinesin family member 2A" O00139 5 62306162-62391025 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Motor protein" "Cancer-related genes, Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004715, HPA004716" Approved Enhanced Nucleoplasm,Nucleoli,Centrosome Yes No 300000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Nucleoli, Centrosome" "HPA004715: AB_2667215, HPA004716: AB_1079211" "unprognostic (2.40e-2)" "unprognostic (3.43e-1)" "prognostic favorable (1.70e-4)" "unprognostic (2.74e-2)" "unprognostic (1.43e-1)" "prognostic favorable (5.45e-4)" "prognostic unfavorable (3.17e-6)" "unprognostic (8.77e-3)" "unprognostic (4.69e-2)" "unprognostic (9.10e-2)" "unprognostic (1.85e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (3.81e-5)" "unprognostic (3.53e-2)" "unprognostic (2.95e-2)" "unprognostic (1.65e-1)" "unprognostic (1.58e-1)" 11.9 7.7 15.6 23.2 20.7 12.8 10.8 15.5 17.7 19.5 0.0 13.8 11.5 12.0 6.3 12.5 17.6 12.9 6.2 17.4 23.0 8.0 5.3 9.8 32.8 17.9 17.5 12.9 10.2 12.3 8.5 16.9 18.4 9.9 14.7 42.7 6.9 11.4 4.8 5.9 15.9 13.1 14.6 18.4 9.6 49.1 16.1 43.6 12.6 6.8 28.9 20.2 7.2 28.0 47.3 46.9 81.4 67.3 28.8 39.6 65.2 51.2 38.5 54.6 67.5 53.1 49.6 111.9 53.3 41.9 67.2 29.1 61.3 37.7 72.5 116.8 44.2 113.8 41.2 27.8 34.7 65.3 42.9 30.5 26.6 50.1 47.5 33.1 49.1 66.5 86.6 66.7 46.9 36.1 104.4 33.1 42.6 12.0 31.9 78.3 59.6 65.3 25.4 55.4 68.0 55.9 67.0 27.9 34.7 55.3 37.6 38.5 39.8 31.9 52.2 40.5 51.3 64.8 94.9 114.1 36.4 74.5 39.8 10.4 4.6 4.7 29.2 5.0 35.3 13.5 29.8 32.7 6.2 10.5 26.3 29.0 7.8 23.2 3.3 9.6 42.3 17.7 15.6 20.7 15.5 17.7 17.4 23.0 17.9 17.5 18.4 14.6 16.1 28.0 30.8 16.0 14.1 54.5 44.1 16.8 41.4 20.1 39.3 45.5 17.9 23.9 9.4 4.3 20.5 20.2 104.3 20.3 73.4 23.1 13.7 37.5 113.8 103.3 47.2 21.4 21.0 42.3 56.7 30.9 22.6 28.2 20.4 43.4 17.7 25.6 19.6 4.4 15.4 52.2 64.5 7.9 14.2 12.9 22.1 130.7 13.1 83.6 12.4 26.2 104.9 28.0 76.2 119.6 156.0 26.6 26.1 13.2 47.8 42.7 13.5 18.7 49.2 92.9 26.3 33.1 25.4 118.9 42.8 34.3 9.5 43.9 77.9 48.9 11.0 56.1 KIF5C ENSG00000168280 "Kinesin family member 5C" O60282 2 148875227-149026759 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transport "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 65.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 252.2;Early spermatids: 568.4;Excitatory neurons: 267.2;Inhibitory neurons: 249.1;Late spermatids: 702.5;Oligodendrocytes: 270.7" "Cancer enhanced" "Detected in many" "glioma: 11.7;prostate cancer: 19.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 117.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035210, HPA062272" Enhanced Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA035210: AB_10671931, HPA062272: AB_2732678" "unprognostic (1.95e-1)" "unprognostic (2.39e-1)" "unprognostic (2.54e-1)" "unprognostic (4.70e-4)" "unprognostic (1.89e-1)" "unprognostic (3.79e-2)" "unprognostic (1.24e-1)" "unprognostic (3.90e-2)" "unprognostic (2.86e-1)" "unprognostic (1.41e-2)" "unprognostic (6.61e-3)" "unprognostic (1.56e-1)" "unprognostic (6.55e-6)" "unprognostic (8.34e-3)" "unprognostic (3.69e-1)" "unprognostic (3.63e-2)" "unprognostic (4.46e-2)" 0.5 5.1 41.3 0.6 17.6 0.0 0.5 13.9 65.2 1.4 0.0 1.1 0.3 0.5 3.7 0.1 0.9 0.1 0.6 28.9 13.7 0.2 0.0 0.2 0.3 15.4 9.0 1.6 2.3 0.3 5.5 0.0 24.6 10.4 0.6 7.8 0.2 2.8 0.3 0.3 0.8 0.4 16.3 0.2 0.6 12.1 49.8 0.1 1.3 0.9 0.2 0.6 1.4 32.0 0.0 0.0 17.8 3.6 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.2 0.0 0.7 0.0 0.2 5.4 0.0 14.1 0.0 1.3 13.7 3.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.7 0.0 0.7 0.0 0.1 0.0 0.8 0.0 0.0 22.4 0.0 9.2 0.0 0.1 0.1 0.0 3.6 117.1 27.1 0.2 0.5 0.2 2.8 0.0 0.0 0.0 0.0 3.3 0.0 3.7 3.0 0.4 0.0 8.8 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.3 17.6 13.9 65.2 28.9 13.7 15.4 9.0 24.6 16.3 49.8 32.0 1.8 0.0 0.0 33.6 2.4 1.3 6.1 0.1 2.2 252.2 8.0 3.7 14.9 4.3 0.0 18.4 108.4 0.0 0.8 1.1 0.0 0.3 568.4 0.9 1.6 6.1 129.7 0.0 267.2 0.0 0.1 4.9 2.0 0.2 0.0 1.1 0.7 0.0 0.2 99.3 249.1 2.7 4.1 0.3 1.9 702.5 8.1 0.8 5.4 10.3 0.8 8.5 2.1 125.2 270.7 0.9 3.4 12.8 1.7 35.8 0.1 0.1 0.0 15.1 6.6 1.6 9.1 15.8 10.7 0.2 0.4 0.0 11.9 0.3 4.9 2.3 KIF7 JBTS12 ENSG00000166813 "Kinesin family member 7" Q2M1P5 15 89608789-89655467 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein, Repressor" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Joubert syndrome, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 14.4;Oligodendrocyte precursor cells: 10.1;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 33.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA043145 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA043145: AB_10969200" "unprognostic (9.52e-2)" "unprognostic (1.07e-1)" "unprognostic (2.74e-3)" "prognostic unfavorable (3.80e-5)" "unprognostic (1.81e-1)" "unprognostic (3.67e-3)" "unprognostic (5.17e-2)" "unprognostic (1.61e-1)" "unprognostic (2.81e-2)" "unprognostic (3.54e-1)" "unprognostic (4.01e-2)" "unprognostic (3.13e-1)" "unprognostic (1.39e-8)" "unprognostic (2.67e-1)" "unprognostic (2.92e-2)" "unprognostic (4.84e-2)" "unprognostic (1.66e-1)" 6.8 3.2 2.0 1.3 1.7 0.2 5.4 1.4 1.7 8.3 3.3 5.6 0.6 7.0 0.5 1.9 7.6 1.2 5.4 1.6 1.7 2.4 0.9 2.2 1.2 1.9 2.0 9.1 1.1 2.2 4.2 1.0 1.8 6.6 0.4 0.2 2.5 2.4 1.3 2.3 3.0 1.4 1.5 2.2 3.4 1.8 2.0 1.0 4.9 0.4 0.3 7.0 4.9 1.1 0.4 2.7 3.9 9.8 9.8 3.6 6.9 15.5 4.9 8.4 6.8 5.4 3.4 0.0 4.0 11.2 2.2 3.7 3.8 0.0 2.0 0.0 15.5 3.5 10.4 6.0 9.3 0.0 0.1 6.7 1.9 5.1 0.0 1.5 3.6 7.9 2.7 0.1 2.9 0.8 5.3 0.5 9.4 0.1 2.4 0.1 0.3 0.0 0.1 1.5 2.2 5.7 16.5 0.2 6.1 2.1 1.8 1.1 7.6 13.5 11.0 33.9 7.3 6.7 2.5 0.0 13.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.7 1.4 1.7 1.6 1.7 1.9 2.0 1.8 1.5 2.0 1.1 0.5 0.0 0.0 14.4 0.0 0.3 1.0 0.5 2.2 0.9 1.8 1.8 5.4 0.0 0.2 0.0 0.0 0.3 0.3 0.7 0.0 0.1 0.5 0.5 4.0 2.1 0.0 0.8 2.9 0.4 0.2 4.3 1.5 0.6 0.0 4.8 1.4 0.1 0.1 0.0 4.5 0.4 0.0 0.0 0.4 0.4 5.6 0.1 0.0 5.6 0.0 1.2 0.0 10.1 0.3 0.1 0.1 4.1 0.0 1.3 0.0 0.3 0.1 0.2 6.6 3.2 3.7 0.7 1.4 0.3 0.4 0.3 0.4 4.2 0.4 0.8 KIFBP "DKFZP586B0923, KBP, KIAA1279, KIF1BP, TTC20" ENSG00000198954 "Kinesin family binding protein" Q96EK5 10 68988803-69043544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 9.5;Cardiomyocytes: 40.7;Cytotrophoblasts: 21.7;Extravillous trophoblasts: 19.5;Fibroblasts: 8.7;Hofbauer cells: 16.7;Syncytiotrophoblasts: 8.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035538, HPA035539" Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "HPA035538: AB_10601130, HPA035539: AB_2674676" "unprognostic (4.28e-2)" "unprognostic (1.80e-1)" "unprognostic (9.64e-2)" "unprognostic (4.19e-1)" "unprognostic (1.96e-1)" "unprognostic (2.13e-3)" "unprognostic (4.23e-3)" "unprognostic (3.72e-2)" "unprognostic (3.52e-2)" "unprognostic (7.74e-2)" "unprognostic (6.23e-3)" "unprognostic (8.74e-2)" "prognostic favorable (2.60e-4)" "unprognostic (5.19e-2)" "unprognostic (9.45e-2)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" 19.9 22.1 21.3 6.7 24.4 1.3 11.2 24.4 32.5 14.0 19.7 11.9 6.4 12.5 15.9 12.2 11.8 12.6 37.3 24.6 23.8 19.5 13.8 9.9 6.7 23.9 22.2 12.3 8.5 33.8 13.6 14.8 24.5 16.6 10.3 25.7 9.8 17.3 30.4 8.7 8.1 15.3 25.7 7.5 11.4 16.2 22.7 7.6 19.2 43.3 9.2 15.2 9.3 28.1 49.1 36.9 33.3 36.1 48.3 42.5 0.2 63.2 58.0 63.4 71.9 40.4 24.7 0.1 20.7 57.3 39.5 40.2 57.0 37.9 63.6 27.5 48.8 9.5 22.0 24.0 32.4 13.3 11.5 26.4 30.4 42.3 37.7 60.5 46.6 15.1 13.1 14.0 78.4 23.3 13.0 15.8 20.7 25.4 84.1 15.5 27.7 7.2 67.4 12.4 25.0 18.1 36.0 48.9 34.8 32.2 60.3 10.2 46.3 28.0 25.7 24.6 64.0 2.8 0.3 9.0 35.9 19.8 15.7 1.8 4.3 2.4 7.3 7.5 8.8 5.1 8.4 7.2 5.5 4.1 9.6 7.8 1.6 6.9 12.9 2.8 8.0 5.0 21.3 24.4 24.4 32.5 24.6 23.8 23.9 22.2 24.5 25.7 22.7 28.1 9.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.7 0.0 0.0 0.0 0.0 21.7 3.5 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 19.5 8.7 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 8.3 0.9 0.0 0.0 0.0 KLHL24 "DRE1, FLJ20059" ENSG00000114796 "Kelch like family member 24" Q6TFL4 3 183635610-183684519 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 54.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056337 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 21: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA056337: AB_2683103" "unprognostic (3.68e-1)" "unprognostic (1.37e-3)" "unprognostic (1.62e-1)" "unprognostic (1.53e-3)" "unprognostic (8.56e-3)" "unprognostic (3.85e-1)" "unprognostic (2.09e-1)" "unprognostic (1.02e-2)" "unprognostic (1.32e-1)" "unprognostic (1.20e-1)" "unprognostic (4.80e-3)" "unprognostic (3.31e-1)" "unprognostic (1.39e-3)" "unprognostic (1.08e-1)" "unprognostic (7.85e-2)" "unprognostic (8.40e-2)" "unprognostic (1.02e-2)" 16.5 13.1 8.4 10.5 22.4 41.0 16.1 71.6 33.2 13.7 0.0 14.9 16.0 15.3 10.3 11.5 10.3 13.4 41.3 8.4 9.0 18.5 20.3 18.8 15.8 18.4 17.6 20.0 15.3 41.7 10.4 13.9 21.0 13.9 14.0 16.1 17.8 11.5 48.5 11.2 14.6 11.3 5.1 16.2 15.1 9.0 21.2 17.8 23.3 46.4 14.7 14.0 11.9 28.3 4.4 4.3 9.9 10.5 22.1 12.0 20.6 2.2 16.9 2.7 4.8 2.8 8.0 8.9 30.1 6.1 25.2 6.2 5.7 2.6 4.8 10.1 7.9 5.4 6.9 2.9 18.9 4.7 7.1 24.7 14.0 2.9 9.2 16.7 14.4 13.8 3.5 28.5 3.7 2.1 7.9 6.0 6.4 6.7 6.5 10.0 7.5 28.7 7.8 13.6 17.5 24.5 10.3 32.1 23.5 14.4 11.8 10.4 12.5 3.4 4.4 5.4 2.9 54.1 38.4 37.7 6.0 7.5 2.2 43.1 20.3 25.0 17.3 22.7 14.7 25.7 14.3 15.8 13.8 27.7 20.7 14.8 40.9 16.3 22.5 10.7 20.5 15.3 8.4 22.4 71.6 33.2 8.4 9.0 18.4 17.6 21.0 5.1 21.2 28.3 44.5 112.2 72.3 88.8 73.4 43.6 30.7 21.8 77.4 39.8 33.2 24.8 137.8 27.1 33.4 31.3 70.9 12.1 63.2 32.0 13.7 28.1 16.1 35.5 42.0 39.5 42.3 26.1 99.5 18.9 18.0 44.5 29.6 49.3 26.0 110.1 33.2 47.7 27.1 60.6 104.3 28.5 46.8 51.9 31.4 7.0 30.7 46.5 35.6 68.4 31.3 24.4 41.2 92.0 185.2 18.1 29.3 24.5 48.5 51.9 52.3 27.7 35.8 45.8 32.9 59.7 48.8 27.9 12.4 46.1 43.9 43.8 49.5 45.1 26.0 44.8 KLHL7 "KLHL6, RP42, SBBI26" ENSG00000122550 "Kelch like family member 7" Q8IXQ5 7 23105758-23177914 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 50.8" "Cell type enhanced" "Detected in all" "Early spermatids: 560.6;Late spermatids: 242.7;Oligodendrocyte precursor cells: 168.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029491, HPA029492" Uncertain Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029491: AB_10599605, HPA029492: AB_10600881" "unprognostic (1.24e-2)" "unprognostic (4.45e-1)" "unprognostic (1.77e-1)" "unprognostic (4.55e-2)" "unprognostic (1.29e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (3.78e-1)" "unprognostic (6.10e-2)" "unprognostic (6.41e-3)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "prognostic favorable (8.98e-5)" "unprognostic (2.46e-2)" "unprognostic (3.55e-3)" "unprognostic (3.23e-2)" "unprognostic (2.27e-2)" 9.5 18.8 12.8 7.0 13.3 12.4 13.0 16.3 15.9 10.5 12.1 9.2 7.8 11.5 12.2 9.0 9.7 9.7 50.8 12.5 13.1 11.9 10.4 7.7 8.3 12.6 12.7 11.8 7.7 10.8 7.3 8.6 12.3 10.1 7.9 14.9 8.5 8.1 9.1 10.9 6.9 10.5 12.2 8.0 6.3 42.2 13.4 12.4 9.2 9.7 9.1 8.7 9.4 14.7 24.7 20.7 55.7 66.3 26.8 23.2 20.3 21.3 31.5 30.7 35.6 25.3 17.5 24.1 16.8 26.2 50.5 26.2 21.5 15.0 25.8 6.4 15.5 15.9 16.7 32.9 20.0 32.5 12.0 20.7 19.1 35.2 28.8 24.2 39.6 29.4 28.3 25.5 50.7 28.4 27.3 51.3 77.0 16.7 24.5 23.7 31.2 22.2 29.2 21.0 33.5 32.5 46.2 22.7 23.3 33.9 18.9 16.9 17.0 25.7 26.6 56.9 25.7 39.9 35.3 58.6 17.0 33.8 31.5 44.1 15.3 67.2 13.0 17.9 13.7 9.2 13.8 12.3 11.1 11.9 10.1 10.0 14.4 9.5 15.8 8.0 16.7 12.6 12.8 13.3 16.3 15.9 12.5 13.1 12.6 12.7 12.3 12.2 13.4 14.7 12.1 22.4 5.5 45.7 13.0 23.6 18.2 13.0 18.2 23.7 12.3 13.5 101.2 8.6 11.3 9.2 29.2 20.7 14.4 5.7 11.7 17.7 560.6 18.3 16.7 15.8 10.8 25.6 74.5 17.6 27.1 19.8 10.2 13.2 21.5 16.3 13.2 7.0 19.7 37.0 75.2 7.6 14.2 16.0 17.2 242.7 16.8 12.6 12.4 35.6 13.4 30.3 8.2 168.9 45.6 19.4 1.9 20.7 12.3 11.5 7.4 13.5 18.8 16.3 6.6 14.3 17.9 83.7 19.7 24.6 33.8 23.7 17.2 12.1 7.0 24.0 KLLN killin ENSG00000227268 "Killin, p53 regulated DNA replication inhibitor" B2CW77 10 87859158-87863533 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 4.5" "Cell type enhanced" "Detected in many" "granulocytes: 5.7;Sertoli cells: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "JURKAT: 5.0;Karpas-707: 5.1" HPA074502 Supported Nucleoplasm,Nucleoli No No "Cluster 42: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Nucleoli "HPA074502: AB_2686695" "unprognostic (4.53e-2)" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (3.71e-1)" "unprognostic (6.53e-2)" "unprognostic (1.37e-1)" "unprognostic (3.59e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (3.12e-3)" "unprognostic (1.57e-2)" "unprognostic (4.79e-4)" "unprognostic (1.38e-2)" "unprognostic (1.00e-1)" "unprognostic (9.02e-4)" "unprognostic (1.60e-1)" 1.0 0.7 1.0 0.6 0.7 0.5 0.6 1.5 1.6 0.7 0.6 0.9 0.4 0.5 1.0 0.4 1.4 0.4 0.5 0.7 0.9 0.9 0.9 0.4 0.8 0.5 0.6 0.4 0.2 0.5 0.5 0.6 0.6 0.4 0.8 1.0 0.3 0.5 4.5 0.4 0.4 0.5 0.3 0.8 0.6 1.0 0.6 1.0 0.7 0.5 0.8 0.3 0.3 1.5 0.8 1.0 1.1 0.7 0.5 0.3 0.8 0.7 0.9 0.5 0.7 0.6 2.6 2.0 0.3 0.2 0.5 0.9 0.7 0.8 0.4 0.5 0.3 0.7 1.5 0.6 0.6 1.4 0.5 0.6 0.8 0.7 0.8 0.9 0.3 5.0 0.4 5.1 0.5 1.8 4.1 1.6 0.4 0.6 0.5 2.6 0.1 2.6 0.4 0.8 0.4 1.0 0.9 0.6 0.1 0.7 1.6 1.2 0.3 0.5 0.3 0.9 0.3 2.9 3.3 2.9 0.9 2.9 0.6 1.6 0.3 0.6 0.2 0.5 0.4 0.4 0.3 0.3 0.3 0.5 0.4 0.3 2.5 0.6 0.8 0.5 0.2 0.2 1.0 0.7 1.5 1.6 0.7 0.9 0.5 0.6 0.6 0.3 0.6 1.5 0.6 0.0 0.0 0.3 0.5 0.1 0.3 0.2 0.6 1.7 1.0 1.3 2.7 1.5 1.3 0.0 0.0 0.7 2.0 3.0 0.0 0.2 3.9 0.8 0.9 0.6 0.0 0.8 0.4 0.2 0.4 1.1 3.6 0.4 5.7 0.3 0.7 0.4 0.3 3.3 0.5 1.8 0.0 1.3 0.0 2.0 0.0 0.6 0.0 0.0 0.3 1.6 0.0 0.0 0.1 0.3 2.5 0.0 0.2 0.3 1.8 1.9 2.3 1.0 6.6 1.1 2.9 0.3 1.2 0.6 0.4 0.5 0.7 0.3 1.3 0.2 KMT2A "ALL-1, CXXC7, HRX, HTRX1, MLL, MLL1A, TRX1" ENSG00000118058 "Lysine methyltransferase 2A" Q03164 11 118436490-118526832 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017794, CAB024270, HPA044910" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "CAB017794: , CAB024270: , HPA044910: AB_2679141" "unprognostic (6.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.83e-1)" "unprognostic (4.56e-1)" "unprognostic (4.96e-2)" "unprognostic (1.72e-3)" "unprognostic (4.52e-3)" "unprognostic (6.07e-2)" "unprognostic (1.61e-1)" "unprognostic (8.46e-2)" "unprognostic (3.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.91e-3)" "unprognostic (7.90e-2)" "unprognostic (3.73e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" 9.9 6.7 8.0 8.5 8.6 19.5 9.9 21.2 9.3 10.3 1.6 10.8 5.4 10.7 8.2 6.8 10.3 6.4 6.5 7.4 9.6 6.7 6.0 10.5 12.4 6.3 6.3 21.2 11.1 9.8 10.2 5.6 6.6 9.2 6.4 23.9 9.4 8.4 7.4 10.4 9.8 7.6 3.2 9.7 8.2 5.3 7.0 14.1 9.9 8.4 11.3 10.7 9.3 11.9 17.9 8.6 20.1 14.5 11.1 16.1 6.2 8.7 11.8 9.0 9.6 17.3 11.4 23.1 15.9 10.8 14.6 16.0 22.9 7.2 17.9 26.0 10.0 45.7 8.9 9.3 6.1 28.5 7.8 7.2 7.4 20.3 24.0 8.9 12.8 13.3 32.8 18.8 9.2 12.7 18.2 12.7 13.6 6.6 13.7 13.8 21.9 6.9 9.8 13.8 18.0 11.8 22.0 6.7 3.9 9.8 11.9 9.1 20.4 14.1 12.7 9.4 14.7 5.1 4.4 15.6 4.7 17.6 8.3 2.1 0.6 1.9 1.6 0.6 1.6 2.5 1.8 1.5 0.3 1.8 1.8 1.2 0.5 2.0 0.7 1.4 1.7 0.4 8.0 8.6 21.2 9.3 7.4 9.6 6.3 6.3 6.6 3.2 7.0 11.9 87.1 70.5 65.8 93.4 83.4 86.9 67.6 29.4 64.9 158.1 76.8 73.9 44.5 40.0 32.2 38.6 152.2 13.9 81.0 26.2 3.9 33.0 10.1 62.1 101.4 74.4 66.4 67.3 146.0 25.6 10.2 65.6 44.4 85.2 29.0 57.5 60.0 27.3 16.8 195.2 170.1 29.6 20.3 37.0 63.7 5.8 66.8 44.8 42.7 62.8 49.9 98.9 78.2 106.6 131.9 28.2 20.1 78.6 83.3 88.3 22.7 10.5 52.7 152.4 65.7 113.4 84.6 25.5 30.7 46.3 80.6 6.0 102.8 55.8 30.6 64.8 KMT2C "HALR, KIAA1506, MLL3" ENSG00000055609 "Lysine methyltransferase 2C" Q8NEZ4 7 152134922-152436641 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 363.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 15.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074736 Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA074736: AB_2686709" "unprognostic (7.75e-2)" "unprognostic (3.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.33e-2)" "unprognostic (1.31e-1)" "unprognostic (5.23e-3)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.45e-1)" "unprognostic (1.06e-1)" "prognostic favorable (8.01e-6)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (3.04e-2)" "unprognostic (2.64e-1)" 12.7 11.2 16.7 7.3 25.7 16.4 12.9 16.7 15.7 15.3 5.5 13.1 5.7 14.3 13.7 14.1 11.9 7.7 10.2 13.0 18.9 8.9 10.4 12.7 8.1 25.3 19.4 16.8 18.5 12.4 12.1 10.3 20.6 9.3 7.6 21.7 14.2 9.0 25.9 17.6 12.8 7.5 12.2 12.2 15.2 13.4 19.1 16.1 14.6 16.9 9.5 11.3 12.7 28.6 13.4 6.1 11.6 11.7 19.0 13.9 10.2 4.7 6.4 5.0 5.5 10.9 4.7 22.4 8.9 11.3 9.2 5.2 14.3 7.5 9.2 12.7 6.5 14.0 7.3 4.5 8.9 22.9 12.8 6.6 9.1 7.1 8.2 7.2 8.4 9.7 22.5 15.0 11.7 12.7 14.8 11.1 6.8 8.5 7.9 9.5 12.3 8.4 5.8 10.9 19.6 12.8 13.4 15.8 6.3 10.6 4.6 15.7 12.8 8.0 4.4 9.0 8.9 15.3 7.7 22.4 10.7 14.7 8.4 6.1 3.0 4.4 1.9 2.7 1.6 6.9 2.0 1.5 1.4 3.9 1.9 1.4 15.2 2.2 2.6 3.7 1.3 0.8 16.7 25.7 16.7 15.7 13.0 18.9 25.3 19.4 20.6 12.2 19.1 28.6 62.4 76.9 71.9 292.8 75.0 89.1 38.3 31.5 62.0 89.0 59.6 35.2 65.8 44.3 72.4 46.0 173.0 38.0 61.9 61.7 5.9 37.6 32.1 94.4 92.1 58.9 67.9 55.5 180.7 33.1 51.7 58.3 89.2 200.5 65.2 52.8 56.7 46.0 33.7 80.8 172.2 53.5 42.7 54.7 79.6 17.3 67.4 90.5 42.7 202.4 77.1 57.7 59.8 299.6 363.2 37.6 49.0 60.2 90.3 53.6 36.3 14.7 46.9 73.0 26.3 83.0 55.5 42.3 33.9 80.9 96.3 127.2 76.8 54.8 39.1 61.4 KMT2D "ALR, CAGL114, MLL2, MLL4, TNRC21" ENSG00000167548 "Lysine methyltransferase 2D" O14686 12 49018978-49060794 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035977 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Nucleoplasm, Plasma membrane" "HPA035977: AB_10670673" "unprognostic (8.33e-2)" "unprognostic (1.49e-1)" "unprognostic (9.14e-2)" "unprognostic (2.52e-1)" "unprognostic (8.07e-2)" "unprognostic (6.91e-3)" "unprognostic (7.35e-2)" "unprognostic (2.29e-1)" "unprognostic (3.57e-1)" "unprognostic (5.14e-2)" "unprognostic (7.23e-2)" "unprognostic (3.07e-1)" "unprognostic (1.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.20e-2)" "unprognostic (7.60e-2)" 19.9 21.9 14.0 17.0 14.4 62.1 20.3 14.7 18.1 20.2 3.8 21.3 13.2 26.9 14.4 25.5 24.1 11.7 23.7 12.1 9.1 18.2 20.5 25.1 17.5 9.3 8.2 25.3 33.2 22.9 25.4 16.2 8.6 19.2 14.7 48.0 22.1 16.2 44.9 30.4 27.9 15.5 3.1 36.6 25.5 23.6 12.7 29.0 26.5 21.9 17.2 19.4 19.4 13.4 32.3 31.9 31.0 24.7 29.3 20.4 32.6 17.3 17.1 20.3 10.9 54.8 14.1 33.4 21.2 23.9 14.0 21.5 38.1 19.9 17.7 22.4 26.7 47.2 37.7 29.9 20.5 59.1 43.2 18.4 25.8 30.7 32.0 27.3 31.8 33.2 55.1 19.2 23.7 37.4 26.8 48.0 29.9 45.4 25.0 37.4 22.4 12.0 18.1 37.2 24.6 21.2 28.1 25.5 19.5 26.1 24.0 44.1 49.8 15.5 30.7 14.5 30.5 24.8 20.9 31.7 17.1 28.0 12.5 0.5 0.2 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 1.5 0.5 0.0 0.2 0.0 0.1 14.0 14.4 14.7 18.1 12.1 9.1 9.3 8.2 8.6 3.1 12.7 13.4 12.9 9.6 19.1 17.6 13.3 14.0 7.8 8.1 14.2 26.8 12.1 7.1 7.8 12.8 10.9 18.4 52.1 8.2 15.3 12.3 1.9 6.3 2.8 10.7 12.7 13.2 13.1 16.0 17.4 6.0 6.0 8.8 24.5 13.1 8.2 23.3 17.9 13.0 9.8 21.9 16.5 10.0 6.1 15.7 18.4 2.4 9.6 15.4 10.6 15.0 14.9 6.4 17.5 12.5 19.8 8.8 9.5 10.9 10.1 11.0 13.3 4.5 9.0 38.4 6.6 14.4 12.5 6.5 3.8 18.9 17.6 11.4 15.3 10.8 10.3 9.6 KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.3;lymphoid tissue: 7.4;testis: 16.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.5;Extravillous trophoblasts: 11.3;Granulosa cells: 22.8;Hofbauer cells: 7.1;Proximal tubular cells: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" 0.2 0.1 0.1 1.9 0.0 5.3 0.3 0.2 0.2 0.2 0.2 1.3 1.6 0.3 0.2 1.0 0.1 0.3 0.1 0.1 0.1 0.5 0.7 0.4 3.6 0.1 0.3 0.0 0.0 0.3 0.0 1.3 0.1 0.1 1.4 0.2 0.2 0.0 0.0 0.8 1.7 0.7 0.0 0.6 0.9 16.9 0.3 7.4 0.3 0.1 3.4 0.5 0.2 0.1 19.1 9.3 18.0 13.8 0.5 2.6 8.6 20.5 8.1 16.0 13.1 11.6 7.2 11.9 6.1 9.3 12.0 21.9 17.6 9.7 16.3 21.4 5.0 35.5 15.5 3.9 0.0 26.2 17.8 0.5 0.4 10.8 6.4 2.1 13.8 20.9 22.9 19.2 18.3 6.1 23.5 6.1 9.4 11.3 9.5 21.2 25.8 5.9 2.6 15.6 15.9 7.7 17.7 10.6 2.1 5.9 11.1 9.0 13.1 18.7 16.3 21.9 11.7 7.5 27.9 22.3 7.6 18.5 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.3 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.1 0.3 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.8 1.8 0.0 8.5 2.6 0.0 1.9 0.2 0.0 3.5 3.5 1.9 0.0 0.0 0.0 0.6 11.3 4.2 0.0 2.9 0.0 22.8 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.1 0.0 0.0 11.5 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.7 1.9 1.7 0.0 0.0 KRAS "KRAS1, KRAS2" ENSG00000133703 "KRAS proto-oncogene, GTPase" P01116 12 25205246-25250936 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049830 Approved NA NA 3300000 "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 22: Epithelial cell types - Mixed function" "HPA049830: AB_2680903" "unprognostic (2.24e-2)" "unprognostic (2.16e-2)" "unprognostic (4.86e-3)" "unprognostic (1.08e-2)" "unprognostic (7.39e-2)" "unprognostic (1.51e-1)" "unprognostic (1.47e-2)" "unprognostic (3.74e-2)" "unprognostic (1.79e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (3.59e-4)" "unprognostic (6.42e-2)" "prognostic favorable (2.75e-5)" "unprognostic (1.95e-2)" "unprognostic (2.37e-1)" "unprognostic (2.81e-2)" "unprognostic (9.97e-2)" 11.8 9.1 11.0 16.2 12.2 27.8 10.0 11.7 12.3 9.5 4.6 22.0 14.0 11.0 6.8 19.3 7.4 13.1 8.6 12.5 12.0 11.7 15.3 13.2 17.9 8.5 9.7 8.0 12.6 11.1 5.7 17.0 8.7 11.8 23.0 22.7 11.9 8.3 7.6 13.6 19.5 13.6 8.1 12.0 20.3 8.9 12.9 17.2 10.8 10.3 17.4 16.2 11.4 8.6 15.9 14.3 39.4 20.7 14.1 19.9 68.9 17.3 22.8 18.0 21.9 51.5 30.7 38.7 10.4 32.0 23.4 18.6 44.9 17.3 34.3 26.7 15.0 37.6 17.6 15.6 15.8 32.8 25.6 18.1 25.5 21.9 20.2 33.6 27.1 28.7 28.0 17.3 27.6 14.1 46.8 56.6 87.6 25.3 7.4 43.4 39.9 59.9 27.2 22.4 11.2 32.4 20.5 24.9 21.8 97.4 28.9 26.9 28.1 18.7 24.8 38.2 22.0 16.4 28.5 41.9 15.4 20.0 15.0 31.2 8.1 13.7 11.6 16.4 7.9 10.7 10.1 13.1 7.9 10.5 13.8 12.4 19.2 11.2 22.4 7.8 7.6 5.8 11.0 12.2 11.7 12.3 12.5 12.0 8.5 9.7 8.7 8.1 12.9 8.6 73.7 48.1 32.1 16.6 90.8 100.9 96.4 57.2 72.3 63.4 59.9 38.0 16.3 64.3 53.6 38.6 73.0 94.2 66.0 161.9 58.7 77.5 3.9 45.4 40.8 77.3 78.8 60.2 42.0 91.8 21.4 50.1 98.4 53.4 24.1 26.6 77.8 56.9 51.5 92.5 45.3 92.9 36.7 53.9 83.7 5.9 40.7 75.3 62.2 28.1 82.9 41.7 49.4 19.6 16.6 114.2 104.7 51.6 85.0 130.1 63.0 52.3 42.5 65.8 26.3 53.7 52.2 53.0 40.3 93.0 155.7 139.1 83.0 36.5 96.7 176.9 KREMEN1 "KREMEN, KRM1" ENSG00000183762 "Kringle containing transmembrane protein 1" Q96MU8 22 29073035-29168333 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 59.1;Skeletal myocytes: 82.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.3;neutrophil: 4.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.6" "Cell line enhanced" "Detected in many" "RH-30: 34.7;U-2197: 59.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058513 Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No 1100000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies, Cytosol" "HPA058513: AB_2683739" 7.3 13.5 10.3 9.5 22.3 4.1 7.6 7.4 10.8 9.1 5.6 13.1 6.6 6.7 8.7 37.2 10.9 4.0 22.7 12.7 7.6 9.0 2.4 11.9 2.9 8.2 9.8 22.2 4.6 48.2 6.5 6.1 8.0 9.1 11.3 4.0 28.3 9.8 28.7 36.3 11.1 6.2 5.6 9.1 9.4 12.5 12.9 22.4 9.5 42.6 16.4 9.2 13.7 8.3 5.2 3.6 11.8 6.2 3.9 11.9 9.9 1.4 12.0 3.8 5.7 16.5 2.4 0.1 4.5 5.6 9.6 24.7 24.6 9.9 4.1 6.2 15.5 1.4 1.7 15.6 4.1 0.1 1.3 11.4 19.7 4.3 2.4 1.6 0.6 10.1 5.4 0.3 4.8 4.4 0.1 1.7 0.5 34.0 2.5 0.8 34.7 0.3 4.1 9.7 23.6 13.1 14.2 5.0 18.3 3.9 18.5 0.9 0.4 15.7 4.8 59.3 1.7 1.2 0.4 0.2 10.0 2.2 18.5 1.3 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 4.6 0.3 0.2 0.6 0.1 0.1 10.3 22.3 7.4 10.8 12.7 7.6 8.2 9.8 8.0 5.6 12.9 8.3 2.0 16.0 18.4 59.1 0.3 15.3 14.0 14.1 7.4 4.4 5.7 6.1 23.9 14.3 18.3 7.3 0.0 15.5 0.3 3.9 1.9 5.4 3.2 6.2 19.7 3.9 0.0 17.2 10.3 4.2 1.8 24.4 8.6 8.0 19.0 5.9 5.3 2.6 2.6 0.0 2.7 19.4 4.1 24.1 6.8 10.8 17.7 2.5 0.0 15.9 2.7 22.2 2.1 10.6 6.3 3.0 9.5 10.5 0.1 10.9 2.2 4.7 18.4 3.4 13.1 82.2 7.9 8.1 6.0 26.3 19.5 5.3 2.3 33.5 10.2 10.5 KRIT1 "CAM, CCM1" ENSG00000001631 "KRIT1 ankyrin repeat containing" O00522 7 92198969-92246166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 177.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049606 Supported Uncertain Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA049606: AB_2680832" "unprognostic (8.12e-2)" "unprognostic (1.11e-2)" "unprognostic (1.83e-2)" "unprognostic (3.75e-2)" "unprognostic (1.94e-1)" "unprognostic (8.93e-2)" "unprognostic (4.10e-3)" "unprognostic (1.06e-2)" "unprognostic (2.30e-3)" "unprognostic (2.18e-1)" "unprognostic (7.24e-2)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "unprognostic (2.82e-1)" "unprognostic (2.61e-1)" "unprognostic (6.18e-2)" "unprognostic (1.04e-1)" 11.4 13.6 6.5 16.2 8.9 8.5 11.8 15.8 11.3 13.1 11.7 12.1 14.5 17.1 14.1 13.3 14.0 15.7 18.9 7.4 9.5 14.1 12.1 10.7 14.7 6.7 6.9 20.3 15.9 23.8 11.4 13.6 7.9 12.1 12.6 16.3 14.1 11.2 16.3 14.0 12.2 14.1 5.7 14.7 13.7 18.8 7.8 19.4 22.4 17.5 15.8 13.6 10.8 14.2 27.6 22.0 26.8 27.4 21.2 15.9 19.6 25.5 18.3 12.0 12.3 18.8 31.1 25.9 24.6 14.8 25.9 24.1 21.9 12.7 18.5 23.0 31.4 25.2 26.6 13.2 15.2 34.9 34.5 22.3 21.8 15.0 16.9 20.7 16.2 21.8 51.4 40.5 18.9 30.7 40.6 26.0 26.6 22.4 16.3 28.4 35.5 34.1 10.8 30.9 27.4 33.5 27.7 38.3 22.9 28.2 22.0 20.6 25.1 37.3 28.2 46.9 18.3 25.6 31.1 50.4 19.5 29.6 34.4 13.4 5.5 5.4 6.5 4.0 6.6 10.8 7.5 9.5 5.6 8.5 9.5 8.3 2.2 12.0 2.9 7.6 7.7 3.3 6.5 8.9 15.8 11.3 7.4 9.5 6.7 6.9 7.9 5.7 7.8 14.2 40.6 16.0 34.3 47.0 38.9 19.9 25.7 27.3 40.5 43.7 35.5 34.3 27.6 20.0 26.8 42.3 33.3 37.3 39.2 22.0 46.9 24.0 29.7 30.0 44.1 36.2 20.4 29.2 76.9 24.2 30.0 39.7 35.7 27.9 36.7 49.4 44.6 29.7 19.3 28.6 92.6 23.1 20.3 22.1 16.2 19.5 51.3 23.4 7.2 35.6 29.9 39.9 41.2 46.8 115.4 22.1 33.1 54.2 38.0 22.4 32.2 36.3 36.9 53.1 39.5 43.8 36.8 177.1 90.1 43.1 25.1 28.0 33.0 41.8 23.7 20.5 KRT1 "EHK1, KRT1A" ENSG00000167768 "Keratin 1" P04264 12 52674736-52680407 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skin 1: 13006.6" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 10030.4" "Group enriched" "Detected in many" 5 "head and neck cancer: 313.8;melanoma: 478.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 2.3" "Lineage enriched" "Detected in single" 23 "T-cells: 2.3" "Group enriched" "Detected in some" 14 "HaCaT: 94.9;hTCEpi: 39.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002153, HPA017917, HPA062908" Enhanced NA NA 35000000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB002153: AB_563790, HPA017917: AB_1852192, HPA062908: AB_2684901" "unprognostic (8.05e-2)" "unprognostic (8.49e-3)" "unprognostic (5.06e-3)" "unprognostic (6.44e-2)" "unprognostic (1.25e-2)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (3.24e-1)" "unprognostic (1.30e-1)" "unprognostic (2.16e-1)" "unprognostic (9.24e-2)" "unprognostic (6.63e-2)" "unprognostic (3.23e-4)" "unprognostic (1.58e-1)" "unprognostic (3.40e-2)" "unprognostic (1.36e-1)" "unprognostic (1.09e-2)" 10.3 1.4 0.0 0.1 0.0 7.7 464.1 0.0 0.1 473.6 0.0 2.6 0.2 1.3 0.4 30.8 0.4 0.3 4.5 0.0 0.0 1.2 3.5 2.6 0.0 0.0 0.0 1.4 3.7 0.0 1.4 1.6 0.0 1.5 0.1 0.0 270.2 0.1 47.8 13006.6 2.0 0.2 0.0 1.6 2.1 1.9 0.0 76.8 2.0 0.8 0.5 0.9 1257.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.7 0.0 39.3 0.0 0.0 0.0 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1681.6 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 19.1 0.0 22.3 0.0 0.0 0.0 17.4 0.0 0.0 234.7 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 267.0 0.0 0.0 0.3 265.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 10.5 0.0 0.0 1.1 10030.4 0.0 7.8 0.0 0.3 0.4 KRT10 "CK10, K10, KPP" ENSG00000186395 "Keratin 10" P13645 17 40818117-40822614 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "skin 1: 15851.5" "Cell type enriched" "Detected in all" 5 "Suprabasal keratinocytes: 12515.3" "Group enriched" "Detected in all" 4 "head and neck cancer: 310.0;melanoma: 562.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "hTCEpi: 718.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000132, HPA012014" Enhanced "Secreted in other tissues" NA NA 18000000000 "Cluster 37: B-cells - Transcription" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "CAB000132: , HPA012014: AB_1852195" "unprognostic (3.07e-1)" "unprognostic (5.19e-2)" "unprognostic (1.71e-1)" "unprognostic (1.37e-2)" "unprognostic (2.00e-2)" "unprognostic (2.60e-1)" "unprognostic (3.02e-2)" "unprognostic (1.29e-2)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (1.00e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (9.32e-5)" "unprognostic (1.64e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-2)" "unprognostic (8.10e-2)" 66.1 47.9 9.4 7.6 9.8 13.4 432.0 9.9 14.9 548.0 10.4 45.2 7.9 55.0 5.5 78.6 45.5 2.2 95.7 9.9 9.8 67.2 64.5 39.7 6.2 9.8 9.7 52.3 69.1 8.2 77.2 3.8 9.8 60.0 3.4 6.9 163.9 5.5 123.1 15851.5 48.2 4.0 9.8 56.8 58.0 64.9 9.8 44.0 53.5 5.8 13.7 48.5 1106.2 10.4 30.3 31.2 11.0 12.2 14.4 11.5 10.4 29.9 16.5 11.4 10.6 11.2 11.7 8.7 42.0 13.1 16.2 158.5 5.4 11.3 13.4 20.1 27.0 9.2 44.7 19.4 16.4 17.1 24.9 10.1 718.0 9.0 17.3 15.0 7.4 12.3 102.1 16.0 12.2 17.3 25.5 16.2 14.6 23.1 19.1 17.8 16.7 17.7 12.3 26.3 8.9 11.1 19.9 46.0 39.0 17.3 35.5 24.3 9.3 17.6 29.5 22.5 34.4 0.4 19.8 22.4 24.5 10.4 23.4 12.8 2.6 11.1 4.8 2.3 5.4 11.2 5.4 6.8 4.1 5.6 5.8 5.9 0.8 6.9 3.2 8.1 5.5 1.9 9.4 9.8 9.9 14.9 9.9 9.8 9.8 9.7 9.8 9.8 9.8 10.4 197.8 35.3 40.0 19.2 187.5 2239.7 320.6 370.2 255.6 47.0 304.4 328.2 194.2 174.5 197.2 112.2 20.9 117.4 163.2 138.9 305.2 232.5 150.4 174.3 172.2 170.0 181.1 87.7 19.1 376.9 295.7 204.5 126.9 164.5 74.3 87.0 159.5 237.6 105.0 21.9 16.3 237.6 195.3 90.3 350.7 65.6 216.6 116.8 393.1 20.6 100.1 221.4 162.7 17.6 35.0 236.0 149.8 174.9 311.6 342.0 155.3 233.2 116.8 68.6 105.2 141.0 167.7 345.1 121.2 295.0 12515.3 160.1 164.3 131.4 173.1 515.6 KRT13 "CK13, K13, MGC161462, MGC3781" ENSG00000171401 "Keratin 13" P13646 17 41500981-41505705 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40925.1;vagina: 13409.3" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 16844.0" "Group enriched" "Detected in many" 5 "cervical cancer: 899.2;head and neck cancer: 758.7;urothelial cancer: 504.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 93 "A-431: 2462.5;HaCaT: 1626.2" "CAB000133, HPA030877, HPA069771" Enhanced Enhanced "Intermediate filaments" NA NA 680000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000133: , HPA030877: AB_2673641, HPA069771: AB_2732141" "unprognostic (1.45e-1)" "unprognostic (6.23e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (9.30e-5)" "unprognostic (7.30e-3)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (5.81e-3)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.45e-6)" "unprognostic (1.80e-1)" "unprognostic (2.76e-1)" "unprognostic (3.04e-2)" "unprognostic (4.33e-1)" 7.7 7.5 0.0 0.0 0.1 6.8 5.1 0.0 0.0 6884.6 0.0 5.6 0.1 10.2 0.0 40925.1 7.0 8.8 9.2 0.0 0.1 5.6 12.8 6.0 0.3 0.0 0.0 9.9 17.2 0.0 26.9 0.0 0.0 115.2 0.0 0.0 6881.1 3.8 9.8 20.5 8.5 14.2 0.0 7.7 31.3 6.9 0.0 13.6 6.1 0.0 1855.2 924.7 13409.3 0.0 2462.5 0.6 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.6 0.8 7.1 0.6 0.0 0.0 1626.2 0.0 0.4 0.0 1.4 0.0 4.5 21.8 0.0 0.0 1.7 1.3 0.0 0.8 0.0 0.0 0.3 0.0 0.0 5.4 1.2 0.0 1.3 0.1 0.1 0.1 14.8 0.3 0.2 1.2 0.3 0.0 10.7 0.0 0.0 1.9 2.0 7.7 0.0 2.3 6.4 5.1 0.0 0.4 0.0 6.6 0.3 6.3 5.8 1.9 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.0 1.1 0.0 0.9 2.8 545.6 17.1 146.8 0.0 2.3 4.6 0.6 1.5 94.5 0.0 0.0 0.1 0.2 0.6 0.0 0.0 1.2 2.7 0.2 11.4 1.2 5.5 0.0 0.0 0.5 12.6 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 8.2 0.0 0.0 3.2 55.9 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.7 286.6 27.1 227.9 0.1 0.1 3.3 0.0 0.0 0.0 16.9 0.2 0.6 16844.0 1.6 0.4 8.8 0.0 0.4 3645.4 KRT14 "EBS3, EBS4" ENSG00000186847 "Keratin 14" P02533 17 41582279-41586895 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6940.5" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 35588.3;Suprabasal keratinocytes: 11677.1" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 5910.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4065.2;HBEC3-KT: 2003.9;hTCEpi: 2448.6;hTERT-HME1: 794.2;U-2197: 696.0" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 36.3" "CAB000134, HPA000452, HPA000539, HPA023040" Enhanced Enhanced "Intermediate filaments" NA NA 1600000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000134: , HPA000452: AB_1079177, HPA000539: , HPA023040: AB_1852201" "prognostic favorable (2.66e-4)" "unprognostic (1.64e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (1.02e-2)" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.00e-2)" "unprognostic (5.74e-3)" "unprognostic (1.49e-8)" "unprognostic (8.91e-2)" "unprognostic (2.00e-1)" "unprognostic (8.80e-3)" "unprognostic (1.22e-2)" 15.8 1.2 0.0 0.0 0.0 2.7 332.7 0.0 0.0 412.0 0.0 1.7 0.0 0.9 0.0 1304.2 1.7 0.0 3.5 0.0 0.0 0.8 2.5 1.7 0.0 0.0 0.0 1.3 2.9 0.0 4.3 2.2 0.1 29.1 0.0 0.0 702.1 3.8 15.9 6940.5 2.1 0.1 0.0 0.9 1.7 1.5 0.0 186.7 2.3 0.0 262.3 0.7 846.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.7 0.0 4065.2 0.0 2003.9 0.2 0.0 0.0 0.1 1.6 0.0 0.1 0.2 2.5 0.1 2448.6 3.0 794.2 0.0 0.1 0.0 0.5 3.6 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.6 0.0 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.4 0.0 0.3 9.1 1.7 696.0 0.0 0.9 0.0 0.0 3.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.5 35588.3 1072.7 181.5 2407.4 0.0 103.5 740.9 0.3 0.0 6.0 0.0 0.0 17.9 3.2 7.3 0.0 0.1 0.0 0.1 0.0 129.0 0.0 0.0 0.0 0.0 127.0 116.5 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 3.4 0.0 0.0 1833.4 0.0 0.0 9.3 1990.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.5 0.0 9.9 702.0 96.8 0.0 2.3 0.0 0.0 0.0 96.3 0.0 0.1 83.2 11677.1 2.5 62.1 0.1 2.3 100.0 KRT16 NEPPK ENSG00000186832 "Keratin 16" P08779 17 41609778-41615899 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 307.2;esophagus: 1025.8;skin 1: 360.7;vagina: 489.4" "Group enriched" "Detected in many" 6 "Basal keratinocytes: 906.1;Basal prostatic cells: 596.6;Suprabasal keratinocytes: 1348.4;Urothelial cells: 506.9" "Group enriched" "Detected in many" 7 "cervical cancer: 713.1;head and neck cancer: 2720.5;melanoma: 712.9" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;hippocampal formation: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTCEpi: 816.8" "Not detected" "Not detected" "CAB000136, HPA000539" Approved Approved "Intermediate filaments" NA NA 1700000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000136: , HPA000539: " "unprognostic (3.95e-3)" "unprognostic (6.90e-2)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (1.41e-2)" "unprognostic (1.00e-2)" "unprognostic (7.14e-3)" "unprognostic (1.03e-3)" "unprognostic (2.05e-1)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (8.23e-2)" "unprognostic (6.53e-8)" "unprognostic (3.81e-1)" "unprognostic (1.83e-1)" "unprognostic (7.40e-2)" "unprognostic (3.61e-2)" 7.1 1.4 0.2 0.1 0.3 0.3 17.4 3.9 0.6 307.2 0.0 0.2 0.0 1.0 0.0 1025.8 0.7 2.4 0.5 1.0 0.0 0.8 0.4 0.2 0.1 0.0 0.0 0.3 0.7 0.0 1.4 0.1 0.1 6.3 0.0 0.0 180.6 37.7 0.5 360.7 0.2 0.1 0.0 0.2 0.6 2.6 0.0 16.9 0.3 0.0 112.1 5.5 489.4 0.4 20.0 1.7 0.0 0.0 0.2 0.0 0.2 1.5 0.4 0.5 0.2 0.3 4.9 0.1 2.9 0.1 0.2 24.8 0.0 5.6 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 816.8 0.3 17.6 0.0 0.0 0.0 0.3 0.0 0.2 0.5 0.0 0.3 0.0 127.1 0.7 0.0 0.2 98.1 0.8 6.2 0.0 0.0 57.1 1.5 0.0 0.9 0.0 0.0 0.2 0.0 1.6 4.5 0.4 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 3.9 0.6 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.3 906.1 596.6 70.1 16.5 0.0 37.8 27.1 0.1 0.0 94.6 1.8 0.0 0.1 0.6 0.0 0.0 1.0 0.0 2.6 0.6 9.2 0.0 0.0 0.0 5.8 3.2 11.5 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 94.1 0.0 0.3 1.1 64.0 0.0 0.0 0.0 0.0 0.0 0.0 82.7 0.0 0.0 0.0 127.3 0.0 0.0 17.1 0.0 0.0 0.0 9.3 0.0 0.3 88.1 1348.4 0.1 3.4 0.0 0.0 506.9 KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 382.1;skin 1: 949.4;urinary bladder: 632.2" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13196.1;Prostatic glandular cells: 5931.6;Urothelial cells: 8499.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 3317.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "hTCEpi: 20287.9;SiHa: 8539.7" "Not detected" "Not detected" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 610000000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" "CAB000029: AB_2133155, HPA000452: AB_1079177, HPA000453: AB_1079176, HPA000539: , HPA045062: AB_2679204" "prognostic favorable (4.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (3.65e-3)" "unprognostic (4.46e-2)" "unprognostic (4.34e-1)" "unprognostic (4.36e-3)" "unprognostic (1.32e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (2.20e-1)" "unprognostic (3.89e-1)" 5.1 0.4 4.9 0.8 5.3 2.8 382.1 3.5 5.8 102.2 3.5 2.0 0.8 4.3 14.1 320.4 6.9 1.9 2.7 6.3 3.3 3.1 0.6 9.8 0.3 3.5 3.4 0.9 2.6 0.5 6.6 7.0 3.5 132.4 0.3 0.3 263.2 116.1 0.9 949.4 0.6 1.0 3.4 0.4 2.3 4.5 3.3 142.7 1.6 0.0 97.8 632.2 212.3 4.7 212.5 0.2 0.0 0.0 0.8 0.9 48.8 1.9 0.4 2.8 2.7 16.8 1.9 1.0 14.7 0.2 0.4 2101.7 0.1 2129.1 1.9 0.3 1.6 2.0 910.8 2.0 0.5 1.9 2.2 0.4 20287.9 1.3 1539.9 0.0 1.0 0.0 1.0 1.5 0.4 0.7 0.7 0.3 0.4 237.2 0.0 0.7 3.1 1.7 0.8 770.5 0.3 0.2 8539.7 3.8 0.9 4.8 0.3 1.4 0.8 0.0 401.5 0.2 1.0 0.9 0.4 3.1 1.4 77.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 3.5 5.8 6.3 3.3 3.5 3.4 3.5 3.4 3.3 4.7 5.6 22.4 7.2 0.3 0.5 139.6 13196.1 338.0 327.8 0.2 158.4 792.8 0.1 0.0 415.8 36.8 0.0 21.5 3.8 0.9 0.0 567.7 0.4 116.9 13.5 54.5 1.8 0.0 3.2 202.1 148.5 87.9 0.0 134.1 3.8 0.0 0.0 0.0 3.8 20.2 0.5 0.6 36.7 0.0 14.1 1.6 2.1 37.5 10.6 3.7 6.7 0.0 0.0 0.5 1.4 1754.5 2.5 212.5 0.0 5931.6 0.1 0.4 100.1 0.0 0.0 0.9 101.0 0.3 0.4 48.2 124.3 5.7 60.8 3.1 0.8 8499.3 KRT2 "KRT2A, KRTE" ENSG00000172867 "Keratin 2" P35908 12 52644558-52652211 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 57 "skin 1: 4660.3" "Cell type enriched" "Detected in some" 14 "Suprabasal keratinocytes: 265.4" "Cancer enriched" "Detected in some" 5 "melanoma: 23.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Cell line enhanced" "Detected in single" "HEL: 2.0" "Group enriched" "Detected in some" 6 "amygdala: 1.7;hippocampal formation: 2.7" "Not detected" "Not detected" "HPA006299, CAB037321" Enhanced Approved "Golgi apparatus,Intermediate filaments,Cytosol" NA NA 9700000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 3: HMC-1 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments, Cytosol" "Golgi apparatus" "CAB037321: , HPA006299: AB_1079180" "unprognostic (1.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.56e-1)" "unprognostic (8.47e-3)" "unprognostic (1.69e-2)" "unprognostic (1.84e-1)" "unprognostic (3.59e-1)" "unprognostic (2.12e-1)" "unprognostic (4.76e-2)" "unprognostic (3.56e-7)" "unprognostic (6.43e-2)" "unprognostic (5.98e-3)" "unprognostic (6.69e-2)" "unprognostic (3.46e-1)" 3.0 0.5 0.0 0.1 0.0 1.0 81.9 0.0 0.0 0.8 0.0 0.9 1.6 0.4 0.3 1.1 0.1 0.0 1.7 0.0 0.0 0.5 1.2 1.0 0.5 0.0 0.0 0.5 1.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 1.6 0.0 47.8 4660.3 0.8 0.0 0.0 0.5 0.7 1.0 0.0 6.8 0.8 0.0 6.1 0.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.1 0.0 0.0 0.0 0.1 0.4 1.5 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.3 9.5 0.0 0.0 0.1 8.8 0.0 0.1 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 265.4 0.1 1.0 0.0 0.6 0.1 KRT25 KRT25A ENSG00000204897 "Keratin 25" Q7Z3Z0 17 40748021-40755331 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 42 "skin 1: 112.3" "Cell type enhanced" "Detected in some" "Early spermatids: 7.8;Late spermatids: 9.2;Spermatogonia: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "RPTEC TERT1: 1.3" "Region enriched" "Detected in some" 7 "cerebellum: 8.6" "Group enriched" "Detected in some" 5 "cerebral cortex: 7.3;hippocampal formation: 4.8" "HPA053977, HPA058943" Enhanced Approved Vesicles NA NA "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA053977: AB_2682329, HPA058943: AB_2683859" "unprognostic (8.19e-2)" "unprognostic (5.89e-8)" "unprognostic (1.79e-1)" 2.6 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.3 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRT4 "CK4, CYK4, K4" ENSG00000170477 "Keratin 4" P19013 12 52806549-52814116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "esophagus: 19735.6" "Cell type enriched" "Detected in some" 18 "Squamous epithelial cells: 5828.7" "Group enriched" "Detected in many" 5 "cervical cancer: 94.3;head and neck cancer: 151.8;stomach cancer: 73.1;urothelial cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HaCaT: 734.9;SK-BR-3: 361.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002154, HPA034881" Enhanced Supported "Intermediate filaments" NA NA 600000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB002154: AB_563803, HPA034881: AB_2674370" "unprognostic (4.04e-1)" "unprognostic (3.22e-3)" "unprognostic (5.16e-3)" "unprognostic (8.52e-3)" "unprognostic (1.20e-1)" "unprognostic (2.64e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.85e-3)" "unprognostic (2.84e-2)" "unprognostic (2.58e-11)" "unprognostic (1.64e-1)" "unprognostic (6.97e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.26e-4)" 1.5 1.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 513.5 0.0 1.1 0.0 1.2 0.0 19735.6 9.5 3.1 7.2 0.0 0.0 0.9 2.6 17.3 0.0 0.0 0.0 1.8 2.8 0.0 8.9 0.0 0.0 4.3 0.0 0.0 2124.1 0.0 2.6 3.9 1.7 0.9 0.0 1.5 8.6 0.8 0.0 2.0 1.0 0.1 1418.0 4.4 1040.2 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.8 0.0 0.1 0.0 734.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.5 1.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.0 1.4 0.0 0.2 0.0 15.5 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 1.0 361.6 0.0 0.0 2.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 1.0 0.9 0.5 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 3.3 0.0 0.0 0.0 6.5 36.9 23.3 0.0 0.5 2.9 0.5 0.0 308.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.5 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.9 6.9 0.0 0.1 53.7 0.0 0.0 0.0 5.3 0.0 0.1 5828.7 0.0 0.0 2.0 0.0 0.0 54.4 KRT5 "EBS2, KRT5A" ENSG00000186081 "Keratin 5" P13647 12 52514575-52520530 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 5865.0;skin 1: 5885.4;vagina: 2150.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 5870.1;Basal prostatic cells: 1037.6;Basal squamous epithelial cells: 1571.3;Squamous epithelial cells: 4370.9;Suprabasal keratinocytes: 2020.2" "Group enriched" "Detected in many" 4 "cervical cancer: 1863.2;head and neck cancer: 3340.4" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 326 "plasmacytoid DC: 32.6" "Lineage enriched" "Detected in single" 326 "dendritic cells: 32.6" "Group enriched" "Detected in some" 7 "HaCaT: 3368.0;HBEC3-KT: 5990.5;hTCEpi: 13326.8" "Region enriched" "Detected in many" 8 "spinal cord: 36.4" "CAB000027, CAB000129, HPA059479" Enhanced Approved "Intermediate filaments" NA NA 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000027: AB_2281083, CAB000129: , HPA059479: AB_2684034" "prognostic favorable (1.27e-4)" "unprognostic (9.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.29e-2)" "unprognostic (1.84e-1)" "unprognostic (1.14e-1)" "unprognostic (1.33e-1)" "unprognostic (7.20e-2)" "unprognostic (2.82e-1)" "unprognostic (1.90e-1)" "unprognostic (1.41e-2)" "unprognostic (1.73e-1)" "unprognostic (6.01e-7)" "unprognostic (3.46e-2)" "unprognostic (5.56e-2)" "unprognostic (7.96e-2)" "unprognostic (2.81e-3)" 10.0 1.7 0.2 1.8 0.8 4.6 252.5 0.7 0.5 826.2 58.9 1.9 0.0 2.0 97.2 5865.0 12.5 2.0 3.8 1.7 0.0 1.3 3.5 6.4 3.0 0.1 0.0 2.2 4.7 0.1 8.2 2.0 0.1 125.8 0.0 0.0 880.3 100.0 9.9 5885.4 1.8 0.6 0.1 1.7 5.0 2.1 0.6 527.1 3.0 0.3 648.6 93.2 2150.9 0.4 50.6 0.0 0.0 0.0 2.3 0.2 0.8 0.0 0.0 0.0 0.0 1.0 0.3 2.4 0.5 0.2 0.0 3368.0 0.2 5990.5 0.2 0.0 0.0 0.2 0.1 0.0 0.6 1.4 2.8 0.3 13326.8 0.6 1049.7 0.0 0.8 0.0 1.8 4.0 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.2 1.0 1.2 0.8 0.9 0.0 0.1 1.2 0.8 0.0 0.0 0.0 0.0 1.5 0.0 0.9 0.5 0.2 10.1 1.0 0.9 4.0 1.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.1 0.2 0.8 0.7 0.5 1.7 0.0 0.1 0.0 0.1 0.1 0.6 0.4 1.7 0.0 1.1 0.0 0.4 5870.1 1037.6 627.1 1571.3 0.0 43.6 226.2 0.5 0.0 180.7 0.0 0.0 0.0 39.8 0.0 0.0 0.5 0.8 31.3 1.2 26.4 0.0 0.0 0.5 0.0 0.0 29.0 0.0 21.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 273.6 0.1 0.6 7.3 286.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 22.2 789.7 0.0 0.1 34.8 0.0 0.0 0.2 33.4 0.0 0.0 4370.9 2020.2 0.0 17.8 0.0 0.1 459.8 KRT6A "CK6C, CK6D, K6C, K6D, KRT6C, KRT6D" ENSG00000205420 "Keratin 6A" P02538 12 52487176-52493257 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Allergen, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 2523.3;esophagus: 7338.5;vagina: 4945.4" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 674.0;Club cells: 200.5;Squamous epithelial cells: 876.0;Suprabasal keratinocytes: 151.4;Urothelial cells: 306.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3892.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "hTCEpi: 9761.7" "HPA045697, HPA061168" Supported Enhanced "Intermediate filaments" NA NA 4500000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (8.10e-3)" "unprognostic (2.11e-1)" "unprognostic (2.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (2.43e-1)" "unprognostic (3.73e-2)" "unprognostic (1.31e-3)" "unprognostic (1.29e-1)" "unprognostic (2.89e-9)" "unprognostic (8.80e-2)" "unprognostic (7.20e-2)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" 3.1 1.5 0.0 1.9 0.0 0.1 6.9 0.0 0.0 2523.3 0.0 1.2 0.0 1.3 0.0 7338.5 9.1 0.9 1.8 0.0 0.0 1.1 2.6 3.4 0.0 0.0 0.0 2.3 3.3 0.0 3.1 8.8 0.0 5.0 0.0 0.0 1025.5 0.0 1.9 480.0 1.3 0.4 0.0 1.4 4.9 1.0 0.0 33.6 1.5 0.0 628.6 19.7 4945.4 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 3.9 0.0 0.0 1143.8 0.0 2414.3 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.5 0.6 0.3 9761.7 0.2 306.7 0.0 0.3 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 14.0 0.3 0.1 0.5 0.0 0.3 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.2 0.2 0.4 0.9 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.5 79.0 674.0 12.0 0.0 0.6 1.7 0.0 0.0 200.5 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 2.6 0.2 0.8 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 5.5 0.0 0.0 0.7 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 100.4 0.0 0.0 24.5 0.0 0.0 0.0 11.8 0.0 0.0 876.0 151.4 0.0 1.7 0.0 0.1 306.8 KRT6B KRTL1 ENSG00000185479 "Keratin 6B" P04259 12 52446651-52452146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 228.2;esophagus: 934.5;skin 1: 285.1;vagina: 229.6" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 217.5" "Group enriched" "Detected in many" 5 "head and neck cancer: 1424.3;melanoma: 472.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 148.7" "CAB000130, HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000130: , HPA045697: AB_2679422, HPA061168: AB_2684440" "prognostic favorable (9.44e-4)" "unprognostic (3.27e-2)" "unprognostic (1.93e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-2)" "unprognostic (2.07e-3)" "unprognostic (2.27e-1)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (5.77e-2)" "unprognostic (9.63e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (9.52e-4)" 0.9 0.2 0.0 2.0 0.0 0.1 16.2 0.0 0.0 228.2 0.0 0.5 0.0 0.1 0.0 934.5 0.2 0.2 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.7 0.0 0.3 0.0 0.0 0.2 0.0 0.0 168.6 0.0 0.3 285.1 0.2 0.0 0.0 0.1 0.7 0.2 0.0 2.1 0.1 0.0 74.3 0.2 229.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 27.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.7 1.1 0.0 0.1 13.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 20.6 1.8 40.4 0.0 0.0 28.7 16.8 0.1 0.0 16.3 0.0 0.0 0.0 0.9 0.3 0.0 46.2 1.8 0.0 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.0 0.0 1.7 1.3 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.6 0.0 0.0 2.8 0.0 0.0 0.0 1.4 0.0 0.2 217.5 32.7 0.0 0.3 0.0 0.6 5.9 KRT6C KRT6E ENSG00000170465 "Keratin 6C" P48668 12 52468516-52473805 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 211.7;esophagus: 799.4;vagina: 333.5" "Cell type enriched" "Detected in some" 60 "Squamous epithelial cells: 234.3" "Group enriched" "Detected in many" 5 "head and neck cancer: 564.7;melanoma: 242.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 94.1" "HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (3.18e-2)" "unprognostic (6.26e-3)" "unprognostic (6.63e-2)" "unprognostic (1.54e-3)" "unprognostic (6.97e-2)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.83e-1)" "unprognostic (1.87e-2)" "unprognostic (3.25e-2)" "unprognostic (2.24e-1)" "unprognostic (2.84e-1)" "unprognostic (4.50e-2)" 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 211.7 0.0 0.1 0.0 0.1 0.0 799.4 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 144.3 0.0 0.1 24.7 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.0 0.1 0.0 9.5 0.1 333.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 94.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.2 1.3 2.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 234.3 2.4 0.0 0.0 0.0 0.2 3.9 KRT74 "K6IRS4, KRT5C, KRT6IRS4" ENSG00000170484 "Keratin 74" Q7RTS7 12 52565782-52573843 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "epididymis: 5.6;skin 1: 16.3" "Cell type enriched" "Detected in some" 5 "Late spermatids: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040655, HPA048596" Enhanced Approved "Nucleoli,Intermediate filaments,Cytosol" NA NA 130000000 "Cluster 61: Skin - Cornification" "Cluster 31: Spermatids - Spermatogenesis" "Intermediate filaments" "Nucleoli, Cytosol" "HPA040655: , HPA048596: AB_2680457" "unprognostic (6.75e-3)" "unprognostic (3.93e-1)" "unprognostic (1.60e-1)" "unprognostic (2.49e-2)" "unprognostic (9.46e-2)" "unprognostic (2.29e-1)" "unprognostic (8.54e-2)" "unprognostic (1.02e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRT81 "Hb-1, KRTHB1" ENSG00000205426 "Keratin 81" Q14533 12 52285913-52291534 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "skin 1: 144.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 41.0;Club cells: 20.4;Ductal cells: 67.3;Pancreatic endocrine cells: 27.2" "Cancer enhanced" "Detected in many" "breast cancer: 46.1;cervical cancer: 49.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 49 "basophil: 170.8" "Lineage enriched" "Detected in many" 49 "granulocytes: 170.8" "Cell line enhanced" "Detected in many" "A-431: 3086.0;A549: 2296.0;MCF7: 700.1;PC-3: 1088.7;U-251 MG: 2151.1" HPA049778 Supported NA NA 130000000 "Cluster 38: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" "HPA049778: AB_2680877" "unprognostic (1.69e-2)" "unprognostic (5.61e-2)" "unprognostic (6.57e-2)" "unprognostic (2.90e-1)" "unprognostic (5.64e-2)" "unprognostic (1.77e-1)" "unprognostic (2.00e-1)" "unprognostic (3.64e-3)" "unprognostic (1.87e-1)" "unprognostic (5.10e-2)" "unprognostic (4.89e-2)" "unprognostic (2.21e-1)" "unprognostic (2.64e-4)" "unprognostic (5.98e-2)" "unprognostic (1.86e-1)" "unprognostic (2.25e-1)" "unprognostic (7.31e-2)" 1.4 0.0 0.3 0.2 0.4 0.3 3.1 0.3 0.6 0.1 0.1 0.3 0.3 0.3 0.2 0.1 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.2 0.0 0.4 0.3 0.0 0.2 0.0 0.1 1.0 0.3 0.3 0.0 0.0 2.1 0.2 0.2 144.7 0.2 0.0 0.3 0.2 0.1 0.4 0.4 0.2 0.9 0.0 0.0 0.1 0.1 0.4 3086.0 2296.0 0.0 0.0 0.0 0.0 0.3 18.6 3.2 23.9 2.2 6.7 0.7 0.0 3.0 0.3 1.6 43.2 0.0 0.0 4.2 4.6 0.0 0.0 1.3 0.2 1.4 0.0 0.2 0.0 0.0 0.4 1.1 32.9 0.0 0.0 0.0 1.6 0.2 700.1 0.3 6.4 0.2 0.1 1088.7 0.5 0.0 10.4 0.6 0.2 0.7 0.0 1.0 179.1 11.1 0.1 0.5 12.9 0.2 0.4 564.4 0.2 2151.1 0.3 4.4 3.1 0.4 7.2 0.2 170.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.3 0.3 0.4 0.3 0.6 0.4 0.4 0.4 0.3 0.3 0.3 0.4 0.4 0.1 0.0 0.0 0.3 0.0 0.0 3.3 4.4 0.0 0.0 41.0 4.6 0.3 0.0 20.4 0.0 0.0 0.1 12.8 0.1 0.0 67.3 0.9 1.9 0.3 0.4 0.0 0.0 3.9 1.3 2.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.2 4.1 0.0 0.4 2.5 0.0 0.1 0.0 1.0 0.0 0.0 6.2 0.0 3.3 27.2 0.0 0.0 0.1 2.6 0.0 0.0 2.0 0.0 0.0 1.2 6.8 0.0 0.1 0.0 0.3 2.9 10.5 0.0 0.0 6.0 KRT83 "Hb-3, KRTHB3" ENSG00000170523 "Keratin 83" P78385 12 52314301-52321398 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "skin 1: 66.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RPMI-8226: 13.3" HPA049778 Supported NA NA 130000000 "Cluster 61: Skin - Cornification" "Cluster 25: RPMI-8226 - Immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA049778: AB_2680877" "unprognostic (7.03e-2)" "unprognostic (2.17e-1)" "unprognostic (2.99e-1)" "unprognostic (3.30e-5)" "unprognostic (3.08e-1)" "unprognostic (1.41e-1)" "unprognostic (1.76e-2)" "unprognostic (2.43e-1)" "unprognostic (1.12e-3)" "unprognostic (7.49e-3)" "unprognostic (2.16e-2)" "unprognostic (1.78e-1)" "unprognostic (2.63e-1)" 1.0 0.0 0.4 0.0 0.7 0.0 0.3 0.6 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 66.8 0.0 0.0 0.8 0.0 0.0 0.2 0.6 0.2 1.0 0.0 0.0 0.0 0.0 1.8 0.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 13.3 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.6 0.5 0.6 0.5 0.6 0.6 0.7 0.8 0.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 KRT85 "Hb-5, KRTHB5" ENSG00000135443 "Keratin 85" P78386 12 52360006-52367481 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "skin 1: 172.7" "Group enriched" "Detected in some" 12 "Early spermatids: 6.2;Late spermatids: 16.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "A549: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA049778 Supported NA NA 110000000 "Cluster 61: Skin - Cornification" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA049778: AB_2680877" "unprognostic (1.36e-2)" "unprognostic (3.93e-1)" "unprognostic (7.27e-3)" "unprognostic (5.71e-2)" "unprognostic (2.36e-1)" "unprognostic (4.72e-2)" "unprognostic (9.22e-4)" "unprognostic (1.64e-2)" "unprognostic (1.74e-2)" "unprognostic (1.38e-1)" 3.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 172.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRT86 "Hb6, KRTHB6, MNX" ENSG00000170442 "Keratin 86" O43790 12 52249300-52309163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "skin 1: 150.5" "Group enriched" "Detected in many" 4 "dendritic cells: 33.1;Early spermatids: 35.5;Late spermatids: 24.3;NK-cells: 11.3;T-cells: 14.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 9 "basophil: 87.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 87.5" "Cell line enhanced" "Detected in many" "A-431: 24.9;A549: 25.7;MCF7: 51.6;RPMI-8226: 32.5;U-251 MG: 14.5" "HPA039798, HPA049778" Supported Approved Cytosol NA NA 160000000 "Cluster 38: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA039798: AB_10674986, HPA049778: AB_2680877" "unprognostic (4.52e-2)" "unprognostic (6.83e-2)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-2)" "unprognostic (2.61e-2)" "unprognostic (6.49e-2)" "unprognostic (1.06e-2)" "unprognostic (1.98e-1)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" "unprognostic (7.22e-2)" 1.2 0.5 0.5 0.2 0.7 2.6 0.5 0.0 0.5 0.2 0.0 0.5 0.4 0.4 0.5 0.1 0.7 0.4 0.1 0.8 0.2 0.2 0.1 0.7 0.0 0.3 0.4 0.1 2.1 0.1 0.1 0.4 0.4 0.3 0.0 0.1 3.8 0.3 0.3 150.5 0.3 0.1 0.2 0.1 0.2 4.0 0.5 0.2 4.1 0.0 0.1 0.8 0.2 1.2 24.9 25.7 0.0 0.0 0.0 0.0 0.3 0.9 0.7 0.3 0.1 0.3 1.3 0.0 1.1 0.0 0.5 1.5 0.0 4.5 0.1 10.9 0.0 0.0 5.4 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.5 12.7 0.0 0.0 0.0 1.8 0.0 51.6 0.0 3.0 0.1 0.2 6.1 0.0 0.0 32.5 0.4 3.2 2.9 0.0 4.5 2.0 2.0 0.0 1.4 0.0 0.8 0.0 1.3 0.1 14.5 0.0 0.0 0.0 0.0 5.3 0.0 87.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.5 0.5 0.7 0.0 0.5 0.8 0.2 0.3 0.4 0.4 0.2 0.5 1.2 0.1 0.0 0.6 0.0 0.3 0.6 2.9 2.0 0.0 0.4 2.8 3.4 0.4 2.8 3.1 0.0 0.0 0.1 33.1 0.2 0.0 2.1 35.5 3.6 0.8 0.2 0.0 0.0 0.5 5.1 1.6 0.3 1.1 4.9 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 2.0 0.0 1.1 24.3 0.3 0.3 1.8 0.0 0.0 0.2 11.3 0.0 0.5 2.9 0.0 0.0 2.1 2.7 0.0 0.6 1.9 0.3 0.0 1.0 0.4 0.8 0.4 0.0 0.1 1.2 14.2 0.0 0.0 3.5 KRT9 "CK-9, EPPK, K9" ENSG00000171403 "Keratin 9" P35527 17 41565836-41572059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 12.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.4;Breast myoepithelial cells: 2.9;Extravillous trophoblasts: 2.2" "Cancer enriched" "Detected in some" 6 "melanoma: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.0;HaCaT: 16.8;U-2197: 3.0;U-937: 5.3" "Region enhanced" "Detected in many" "basal ganglia: 25.1" "HPA007261, CAB037322" Supported NA NA 24000000000 "Cluster 63: T-cells - Adaptive immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB037322: , HPA007261: AB_1079182" "unprognostic (2.13e-2)" "unprognostic (5.08e-2)" "unprognostic (4.97e-2)" "unprognostic (3.65e-2)" "unprognostic (2.89e-3)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (5.92e-7)" "unprognostic (1.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.40e-1)" "unprognostic (4.15e-2)" 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 2.5 0.1 0.1 0.1 0.0 0.0 0.2 0.0 12.1 0.0 0.0 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.9 0.0 0.0 0.0 0.1 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.9 0.0 0.0 0.0 0.1 0.2 L1CAM "CD171, HSAS, HSAS1, MASA, MIC5, S10, SPG1" ENSG00000198910 "L1 cell adhesion molecule" P32004 X 153861514-153886173 "CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hereditary spastic paraplegia, Hirschsprung disease, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;intestine: 48.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 84.6;Excitatory neurons: 23.7;Horizontal cells: 33.7;Inhibitory neurons: 23.3;Melanocytes: 44.4" "Cancer enhanced" "Detected in many" "melanoma: 34.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 372.4;BJ hTERT+ SV40 Large T+ RasG12V: 200.8;HeLa: 258.1;RH-30: 162.6;RPTEC TERT1: 218.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010896 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 67000000 "Cluster 24: B-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Plasma membrane" "CAB010896: AB_609903" "unprognostic (1.33e-3)" "unprognostic (3.43e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (8.51e-10)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (9.44e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.13e-1)" "unprognostic (9.12e-2)" "unprognostic (8.52e-3)" "unprognostic (8.02e-2)" "prognostic unfavorable (1.17e-4)" "unprognostic (3.07e-1)" "unprognostic (6.31e-2)" "unprognostic (1.69e-1)" "unprognostic (7.47e-3)" 3.5 27.2 20.4 7.6 23.0 0.5 2.1 23.0 42.8 8.4 0.0 48.5 4.2 2.4 2.1 4.4 3.4 2.4 12.1 12.6 42.4 18.5 0.9 0.6 3.2 9.0 2.5 1.3 2.2 0.1 14.4 0.6 6.1 8.3 4.7 15.7 4.8 9.0 0.9 9.2 13.0 5.4 0.0 0.9 11.3 0.8 3.2 0.7 2.5 2.1 1.8 6.1 9.6 13.2 95.2 7.2 27.6 0.2 0.0 0.0 11.8 131.6 372.4 123.6 200.8 37.8 1.0 0.0 121.8 0.9 103.2 3.9 3.5 2.3 64.1 0.3 1.0 0.0 258.1 6.1 0.4 0.3 20.4 0.9 1.6 18.7 12.9 0.2 0.1 0.1 0.3 0.3 0.6 127.9 0.4 2.6 6.5 0.4 4.7 0.2 162.6 0.9 218.4 1.9 81.4 53.0 73.4 64.2 54.1 61.0 6.7 1.7 0.3 0.1 52.6 5.8 63.7 1.1 1.6 1.0 0.9 1.1 105.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 23.0 23.0 42.8 12.6 42.4 9.0 2.5 6.1 0.0 3.2 13.2 0.4 0.0 0.0 2.6 1.3 1.1 0.1 0.6 3.4 11.6 0.0 0.4 1.2 0.0 0.0 84.6 4.2 0.3 0.1 0.0 0.0 0.5 0.0 0.3 0.1 1.9 0.0 0.0 23.7 0.0 0.2 1.3 0.0 0.6 0.0 0.0 1.4 0.0 0.1 33.7 23.3 0.0 0.0 0.0 1.1 0.0 0.9 0.3 44.4 5.6 0.0 1.5 0.0 1.5 1.7 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.1 10.4 0.0 2.2 0.6 0.4 0.1 0.0 1.3 0.1 1.5 0.0 0.0 0.1 LAGE3 "CVG5, DXS9879E, DXS9951E, ESO3, ITBA2, Pcc1" ENSG00000196976 "L antigen family member 3" Q14657 X 154477769-154479257 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036122, HPA036123" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Nuclear bodies" "HPA036122: AB_2674951, HPA036123: AB_10601926" "unprognostic (1.70e-1)" "prognostic favorable (5.29e-6)" "unprognostic (1.09e-2)" "prognostic unfavorable (7.60e-4)" "unprognostic (2.28e-1)" "unprognostic (9.65e-2)" "prognostic unfavorable (8.63e-5)" "unprognostic (1.99e-2)" "unprognostic (2.08e-1)" "unprognostic (3.04e-2)" "unprognostic (4.88e-3)" "unprognostic (6.73e-2)" "prognostic unfavorable (5.42e-5)" "unprognostic (7.37e-2)" "unprognostic (3.57e-2)" "unprognostic (2.31e-1)" "unprognostic (1.80e-1)" 11.9 29.1 41.2 7.7 43.0 19.4 12.1 41.2 52.4 16.9 36.9 14.2 6.8 12.3 8.4 15.0 11.1 5.9 21.9 44.3 40.6 14.2 20.9 10.8 10.2 38.9 38.3 18.5 25.1 8.9 34.0 5.4 40.4 16.7 4.7 4.6 16.5 6.5 24.4 19.8 12.2 4.0 39.9 16.2 15.2 9.6 41.1 13.4 9.7 10.2 8.9 17.2 13.6 43.4 44.7 41.6 15.1 32.1 16.0 13.3 44.7 13.3 9.4 19.7 22.0 27.0 23.4 94.2 118.6 17.5 34.9 19.1 37.5 13.2 6.8 53.9 59.9 34.4 38.3 15.6 27.2 46.1 49.1 20.5 8.6 29.6 7.7 15.0 14.1 44.9 34.2 44.4 27.3 104.6 61.9 134.3 28.5 59.5 99.7 54.0 26.0 106.4 11.6 12.0 41.8 38.8 31.0 73.8 57.1 10.4 32.0 33.5 15.8 14.1 41.9 59.6 51.3 104.2 117.5 145.0 24.8 81.8 33.3 27.1 25.8 10.9 26.4 25.5 33.9 40.4 36.5 38.6 35.6 33.7 82.0 41.7 2.8 47.0 20.8 66.5 31.7 40.0 41.2 43.0 41.2 52.4 44.3 40.6 38.9 38.3 40.4 39.9 41.1 43.4 41.7 9.6 14.7 8.5 57.1 58.0 50.1 68.4 70.6 54.9 84.5 107.8 30.8 58.6 34.2 35.0 8.4 62.4 58.5 40.0 127.2 50.7 2.0 15.3 22.4 46.5 56.4 79.7 10.9 93.4 119.9 40.0 27.5 14.8 46.9 75.7 33.5 49.6 126.3 23.5 8.3 50.8 67.1 37.4 93.1 6.3 41.7 55.6 92.5 3.7 63.4 87.2 74.2 4.5 9.3 40.9 28.4 36.9 65.0 46.1 38.5 72.6 33.0 18.4 6.6 35.3 31.0 43.5 100.9 61.4 56.0 56.8 51.8 56.8 54.3 45.2 LAMA1 LAMA ENSG00000101680 "Laminin subunit alpha 1" P25391 18 6941742-7117797 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.9" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Distal enterocytes: 173.6;Granulosa cells: 77.3;Intestinal goblet cells: 44.2;Paneth cells: 35.8;Proximal enterocytes: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 56.0;ASC diff: 41.0;BEWO: 199.6;hTEC/SVTERT24-B: 41.7;SK-MEL-30: 38.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" CAB010179 Enhanced "Secreted to extracellular matrix" NA NA "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB010179: AB_2133741" "unprognostic (2.75e-1)" "unprognostic (3.66e-4)" "unprognostic (2.08e-1)" "unprognostic (3.56e-1)" "unprognostic (4.97e-3)" "unprognostic (3.66e-2)" "unprognostic (1.72e-2)" "unprognostic (7.94e-2)" "unprognostic (2.23e-2)" "unprognostic (3.43e-2)" "unprognostic (3.02e-1)" "unprognostic (6.80e-2)" "unprognostic (1.92e-1)" "unprognostic (1.78e-2)" "unprognostic (4.85e-1)" "unprognostic (3.47e-2)" "unprognostic (7.34e-3)" 0.7 0.0 2.0 0.2 1.5 0.0 1.6 1.9 1.1 0.8 0.5 0.1 0.0 0.9 1.4 0.1 0.2 0.0 0.2 2.0 2.0 2.9 0.1 0.3 0.0 2.0 2.8 1.4 1.1 0.0 1.0 0.1 2.1 0.2 0.0 0.4 1.3 0.6 0.0 0.2 0.0 0.3 2.2 0.1 0.0 5.9 3.0 0.1 2.5 0.0 0.0 0.3 0.2 2.9 0.0 0.0 56.0 0.0 41.0 36.5 199.6 2.0 9.8 9.9 21.5 24.4 0.0 0.0 0.5 3.4 8.0 0.1 0.0 7.3 4.1 0.0 3.2 0.0 11.8 0.0 4.8 0.0 0.0 31.1 1.1 41.7 23.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 2.8 0.0 0.0 38.4 11.6 0.0 0.0 0.0 7.5 20.5 4.2 0.1 0.0 0.0 0.0 3.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 1.9 1.1 2.0 2.0 2.0 2.8 2.1 2.2 3.0 2.9 2.6 6.4 0.0 90.8 0.0 0.0 0.8 0.8 0.6 0.5 2.3 7.2 1.9 4.3 0.0 0.0 0.0 4.1 0.0 173.6 0.0 0.0 1.6 4.1 0.6 0.2 1.2 0.0 1.4 0.5 3.1 4.2 0.0 4.3 0.0 77.3 0.0 0.1 0.9 0.0 1.7 44.2 0.0 0.0 0.0 3.7 0.0 0.2 0.0 15.0 0.0 3.4 0.0 4.0 1.8 0.0 35.8 0.0 0.0 1.0 47.5 1.4 0.1 0.3 0.0 0.6 3.4 0.4 2.5 0.3 0.0 4.8 0.2 4.6 16.5 0.3 LAMA3 "BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa" ENSG00000053747 "Laminin subunit alpha 3" Q16787 18 23689453-23956222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 171.0;Gastric mucus-secreting cells: 138.1;Pancreatic endocrine cells: 585.5;Paneth cells: 170.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "HBEC3-KT: 1237.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009309, CAB010757" Uncertain Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 1800000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "CAB010757: AB_477162, HPA009309: AB_1079224" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (6.36e-2)" "unprognostic (3.82e-3)" "unprognostic (2.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (3.58e-6)" "unprognostic (1.98e-1)" "unprognostic (2.36e-1)" "unprognostic (3.15e-1)" "unprognostic (9.91e-3)" "unprognostic (3.98e-2)" "unprognostic (1.13e-1)" 10.0 1.2 8.3 8.5 3.6 0.1 20.3 2.8 5.9 15.4 5.4 13.6 17.8 15.6 4.7 14.5 12.0 7.4 4.2 4.1 3.5 3.2 1.7 20.9 4.1 3.8 5.9 5.7 4.7 10.9 3.0 24.8 3.6 12.2 8.4 3.7 21.3 13.5 2.0 32.1 19.7 6.9 3.5 0.8 31.8 3.3 4.3 9.5 2.3 1.7 4.1 12.2 23.1 2.9 140.5 15.7 0.1 0.1 6.9 1.3 0.3 2.6 1.8 1.3 1.7 5.4 159.5 0.1 17.3 1.8 0.4 248.5 0.2 1237.9 0.9 0.2 8.8 0.0 5.6 2.8 1.2 0.0 0.6 1.6 139.1 0.8 140.0 0.9 5.2 0.2 0.0 0.2 1.6 0.4 0.1 0.1 1.4 42.6 14.4 2.6 0.1 0.2 51.8 15.4 0.6 2.5 4.9 2.0 0.4 0.3 4.5 1.8 12.3 0.9 1.0 6.7 0.6 0.2 0.1 0.6 2.9 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.3 3.6 2.8 5.9 4.1 3.5 3.8 5.9 3.6 3.5 4.3 2.9 28.8 115.4 26.4 13.1 0.7 31.4 104.2 117.1 100.7 6.0 21.8 41.8 2.3 4.3 20.4 1.8 0.0 0.6 0.5 171.0 0.0 30.2 3.9 21.5 4.3 7.5 8.3 0.0 8.3 34.4 0.4 3.6 138.1 24.0 5.7 9.5 2.5 0.9 0.2 0.0 18.5 23.7 4.1 0.0 1.5 4.5 5.9 2.0 1.8 68.4 0.6 0.2 0.0 1.0 2.0 585.5 170.1 3.4 0.2 45.6 39.5 0.0 15.6 2.2 6.6 1.5 22.1 4.5 4.0 28.2 9.9 0.1 1.5 5.9 28.4 18.2 LAMB1 CLM ENSG00000091136 "Laminin subunit beta 1" P07942 7 107923799-108003213 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 185.6;Fibroblasts: 99.6;Peritubular cells: 141.8;Theca cells: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 593.0;ASC TERT1: 815.3;HSkMC: 779.6;TIME: 547.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004056, HPA004132, CAB004256" Enhanced "Secreted to extracellular matrix" NA NA 250000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "CAB004256: AB_627867, HPA004056: AB_1079226, HPA004132: AB_1079225" "unprognostic (2.39e-1)" "unprognostic (6.45e-3)" "unprognostic (2.01e-1)" "unprognostic (6.75e-2)" "unprognostic (3.45e-3)" "unprognostic (8.26e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (3.77e-2)" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "unprognostic (3.44e-1)" "unprognostic (5.01e-2)" "unprognostic (2.87e-2)" "unprognostic (4.50e-3)" "unprognostic (1.75e-1)" "unprognostic (4.45e-2)" "unprognostic (1.46e-1)" 141.4 21.8 1.2 26.5 1.6 0.1 74.1 0.9 1.7 46.4 23.0 87.0 29.3 78.9 3.3 25.2 44.1 53.4 53.9 2.4 0.7 81.4 14.7 104.3 9.4 0.0 0.8 29.4 48.2 12.1 11.8 154.3 0.2 18.1 40.4 0.7 24.6 29.7 20.4 39.3 67.5 73.2 0.1 42.4 49.5 11.4 1.4 19.7 43.5 40.6 5.2 53.5 31.0 0.4 94.5 148.6 77.3 3.6 593.0 815.3 291.9 103.5 182.5 68.6 72.1 306.7 166.6 0.0 127.7 200.3 90.8 41.9 24.8 143.6 49.9 0.1 24.8 4.8 52.6 87.9 364.3 0.0 2.8 779.6 49.0 175.9 193.4 409.2 450.0 2.8 17.0 0.0 126.5 29.9 0.1 0.5 42.9 54.9 103.6 0.4 51.9 0.3 238.5 96.0 24.3 142.1 75.1 100.9 68.5 180.2 37.6 1.1 547.1 179.9 44.3 60.2 133.1 0.0 0.2 0.4 89.9 0.0 301.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.9 1.7 2.4 0.7 0.0 0.8 0.2 0.1 1.4 0.4 81.8 0.0 5.6 2.9 2.2 8.9 5.2 16.7 10.8 12.1 2.0 9.5 16.3 15.7 7.6 27.6 4.2 85.5 3.5 10.5 3.9 18.0 2.0 22.6 185.6 57.8 19.2 0.0 51.6 11.2 27.1 99.6 2.6 34.6 2.5 2.9 20.7 3.5 10.1 8.4 23.7 8.0 8.2 2.8 3.8 4.7 71.1 2.4 8.8 11.2 2.0 2.1 5.2 6.0 3.2 21.6 17.0 141.8 0.4 3.6 9.5 11.6 2.9 8.6 52.6 10.2 54.4 5.5 5.1 4.7 6.7 32.6 3.2 174.7 19.2 2.1 LAMB3 "BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa" ENSG00000196878 "Laminin subunit beta 3" Q13751 1 209614870-209652425 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Amelogenesis imperfecta, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.2;urinary bladder: 73.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 370.0;Basal respiratory cells: 447.6;Pancreatic endocrine cells: 853.8;Urothelial cells: 392.7" "Cancer enhanced" "Detected in all" "head and neck cancer: 223.9" "Region enriched" "Detected in many" 7 "cerebral cortex: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 353.8;HaCaT: 538.2;HBEC3-KT: 1315.0;hTCEpi: 412.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA007584, HPA008069, CAB078183" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 20000 "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB078183: AB_2665825, HPA007584: , HPA008069: AB_1079228" "prognostic favorable (8.43e-4)" "unprognostic (3.08e-2)" "unprognostic (1.46e-2)" "unprognostic (2.88e-2)" "unprognostic (8.00e-2)" "unprognostic (1.60e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.62e-5)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.55e-4)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.02e-1)" "unprognostic (2.38e-1)" "unprognostic (6.01e-2)" "unprognostic (4.92e-3)" 10.9 16.0 2.6 13.1 2.9 10.7 20.7 0.9 21.3 13.2 0.5 26.2 31.5 18.0 2.6 47.2 16.4 11.9 6.8 2.9 2.1 16.3 9.3 28.4 1.2 1.5 1.5 1.1 4.2 0.1 1.7 5.8 1.6 25.9 16.6 0.2 41.5 24.1 6.8 42.1 43.7 2.3 1.7 1.0 73.2 1.0 1.9 5.8 1.2 0.3 13.2 73.1 32.6 2.8 178.4 25.8 0.0 0.4 18.1 11.7 1.0 5.1 15.4 6.0 9.1 68.9 353.8 0.1 15.1 3.7 8.9 538.2 0.1 1315.0 9.1 13.1 1.4 1.1 86.9 1.1 2.4 1.0 1.3 2.6 412.8 19.1 253.4 11.7 6.4 0.1 2.5 6.7 1.9 0.3 0.2 1.2 0.6 81.0 74.0 0.2 17.1 165.4 70.9 109.0 0.5 0.5 73.9 8.5 15.4 1.0 2.0 9.7 138.3 29.1 61.3 1.0 104.6 1.7 3.4 0.4 42.2 0.8 2.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 2.6 2.9 0.9 21.3 2.9 2.1 1.5 1.5 1.6 1.7 1.9 2.8 0.4 221.2 67.7 1.6 1.2 109.7 370.0 447.6 159.9 0.3 11.5 64.4 8.4 4.3 168.5 47.8 0.0 1.1 0.4 247.5 0.0 180.5 6.0 50.8 10.0 3.5 7.8 0.4 2.5 153.0 1.4 7.5 195.7 135.0 18.4 0.2 0.4 3.9 2.0 3.3 2.3 71.7 18.3 0.3 30.0 10.9 1.8 9.9 8.8 0.0 2.1 0.4 0.0 1.0 1.7 853.8 229.1 0.7 2.1 185.0 111.9 2.3 52.2 0.3 0.0 5.3 10.4 0.3 0.6 51.7 26.0 0.5 4.0 0.0 63.1 392.7 LAMC2 "BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa" ENSG00000058085 "Laminin subunit gamma 2" Q13753 1 183186238-183245127 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 39.3" "Cell type enriched" "Detected in many" 5 "Pancreatic endocrine cells: 1531.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 231.3" "Region enhanced" "Detected in some" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 574.7;CAPAN-2: 501.6;HBEC3-KT: 2492.2;hTERT-HME1: 1487.5;RPTEC TERT1: 579.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004257, HPA024638, HPA046539, CAB078165" Enhanced Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" No No 130000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum, Golgi apparatus" "CAB004257: AB_627873, CAB078165: AB_2665800, HPA024638: AB_1852689, HPA046539: " "unprognostic (7.27e-3)" "unprognostic (7.21e-3)" "unprognostic (3.24e-1)" "unprognostic (6.20e-3)" "unprognostic (9.43e-2)" "unprognostic (4.94e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.20e-6)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (7.11e-5)" "unprognostic (2.77e-1)" "unprognostic (7.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" 3.5 0.1 0.2 16.2 1.9 0.1 20.9 2.6 0.6 15.1 0.2 12.1 2.6 12.3 2.1 7.7 34.9 13.0 3.0 0.2 0.2 13.8 0.7 24.9 8.0 0.0 0.1 1.0 3.3 0.0 4.2 10.9 0.1 5.4 12.9 0.1 12.9 6.1 1.7 17.5 15.0 3.3 0.0 0.9 14.9 2.8 0.1 11.3 18.5 2.3 12.3 39.3 6.3 0.2 574.7 25.4 0.0 0.7 4.9 11.9 40.2 4.3 4.7 2.1 0.7 41.4 501.6 0.0 207.9 1.4 16.4 252.4 0.1 2492.2 2.7 0.7 0.2 0.0 0.5 0.1 1.2 0.0 0.2 6.1 189.7 6.0 1487.5 2.3 32.6 0.0 0.0 0.2 2.5 1.1 0.0 0.1 4.5 206.7 35.2 0.1 1.2 0.0 579.4 147.1 30.5 0.1 14.7 0.4 0.9 14.9 2.0 2.7 3.8 2.2 30.2 15.0 7.8 0.9 0.7 0.7 4.1 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.9 2.6 0.6 0.2 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.5 218.0 17.8 0.0 0.2 86.3 227.1 232.7 105.3 0.0 8.2 26.2 2.3 10.0 56.8 23.9 0.0 30.7 0.4 74.4 0.0 183.4 19.6 68.9 3.6 7.8 9.0 0.0 0.4 94.0 11.7 17.2 59.7 97.4 0.0 0.0 0.0 0.0 2.5 0.0 0.3 34.1 14.2 0.0 4.9 11.8 3.4 3.1 8.8 1.0 2.6 0.0 0.0 0.0 0.3 1531.1 91.2 0.4 0.3 302.0 16.7 0.2 69.3 0.0 0.0 3.4 9.6 3.6 1.0 60.3 29.7 83.3 5.3 0.1 15.3 169.9 LAMC3 DKFZp434E202 ENSG00000050555 "Laminin subunit gamma 3" Q9Y6N6 9 131009174-131094473 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 48.7" "Group enriched" "Detected in many" 4 "Leydig cells: 118.4;Peritubular cells: 364.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.0;EFO-21: 17.3;Hep G2: 6.1;SiHa: 6.7;U-2 OS: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022814 Enhanced "Secreted to extracellular matrix" NA NA 1100000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" "HPA022814: AB_2670960" "unprognostic (9.77e-2)" "unprognostic (1.90e-1)" "unprognostic (9.55e-3)" "unprognostic (2.09e-1)" "unprognostic (2.15e-1)" "unprognostic (1.22e-2)" "unprognostic (1.38e-2)" "unprognostic (2.28e-3)" "unprognostic (6.27e-2)" "unprognostic (1.83e-1)" "unprognostic (1.58e-1)" "unprognostic (3.38e-1)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (1.63e-1)" "unprognostic (3.34e-1)" "unprognostic (7.83e-2)" 1.5 13.5 1.3 0.3 1.8 0.0 1.5 1.3 2.4 22.3 1.9 1.6 0.4 3.3 3.5 1.7 1.1 2.7 1.2 1.4 1.2 9.2 4.9 23.3 0.0 1.4 1.3 1.7 3.5 0.9 11.6 48.7 1.2 4.2 0.1 0.0 1.4 3.8 0.3 8.6 0.3 0.3 1.2 11.3 0.5 19.0 1.7 0.2 1.2 1.1 0.0 15.0 8.2 2.0 0.0 0.5 4.0 0.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 17.3 0.0 0.3 0.0 0.3 0.0 0.0 0.0 2.2 0.0 1.5 6.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.2 2.2 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.4 0.1 6.7 0.0 2.6 0.4 0.0 0.7 0.0 0.0 5.3 0.4 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 1.3 1.8 1.3 2.4 1.4 1.2 1.4 1.3 1.2 1.2 1.7 2.0 1.5 0.0 0.0 1.0 0.0 6.8 0.0 0.0 0.0 0.0 0.4 0.4 1.3 0.0 0.0 1.8 0.0 0.7 0.0 0.0 0.0 0.1 1.9 1.6 48.5 1.7 0.0 0.0 1.7 0.0 0.8 20.7 0.0 1.1 0.0 27.8 3.6 0.1 1.5 0.0 4.1 0.2 0.0 0.0 10.2 12.6 118.4 0.5 10.6 36.5 0.1 0.0 0.0 0.0 1.0 0.1 0.0 364.1 0.0 0.2 0.0 0.2 0.0 0.0 46.0 0.1 10.0 1.0 3.5 0.0 4.4 1.0 0.8 38.1 0.0 0.1 LARP7 "DKFZP564K112, HDCMA18P, PIP7S" ENSG00000174720 "La ribonucleoprotein 7, transcriptional regulator" Q4G0J3 4 112637107-112657592 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, Spermatogenesis, Transcription, Transcription regulation" RNA-binding "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026842, HPA027930" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "HPA026842: AB_10611116, HPA027930: AB_10601233" "unprognostic (3.01e-1)" "unprognostic (6.63e-2)" "unprognostic (5.72e-2)" "unprognostic (2.65e-1)" "unprognostic (1.07e-1)" "unprognostic (1.13e-1)" "unprognostic (2.28e-2)" "unprognostic (1.68e-1)" "unprognostic (1.82e-2)" "unprognostic (1.12e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (1.40e-2)" "unprognostic (1.26e-1)" "unprognostic (1.51e-1)" "unprognostic (2.28e-2)" "prognostic favorable (4.33e-4)" 37.2 31.6 26.3 32.8 28.3 44.6 35.7 28.6 34.6 28.0 28.0 36.2 33.8 33.3 29.8 31.7 25.8 30.5 59.6 24.9 33.5 40.2 44.1 28.1 44.9 30.2 30.2 34.2 18.3 29.9 20.1 34.1 31.0 32.1 36.7 31.5 23.2 27.2 46.6 30.6 33.2 29.5 28.3 36.9 31.5 24.6 29.1 42.2 38.7 45.3 40.3 33.0 21.8 30.8 42.9 34.9 77.7 44.3 50.7 61.6 44.0 55.3 40.6 45.3 42.0 27.9 62.0 95.4 43.7 46.9 42.2 29.6 75.1 45.2 60.2 86.8 52.1 56.4 35.2 41.9 41.0 131.6 84.6 49.3 50.7 40.4 25.1 62.6 40.4 47.6 71.4 51.1 55.3 35.2 107.4 56.7 182.2 67.5 28.2 62.9 66.2 44.3 68.8 44.8 46.5 64.4 32.0 83.4 55.4 131.4 35.1 61.0 43.7 42.4 49.5 47.7 57.6 34.7 62.5 97.6 57.7 52.4 49.2 70.1 28.1 49.9 32.8 43.1 30.3 48.1 33.9 34.2 25.3 47.4 32.3 31.3 33.2 38.7 60.7 64.0 37.9 20.8 26.3 28.3 28.6 34.6 24.9 33.5 30.2 30.2 31.0 28.3 29.1 30.8 66.1 96.1 79.2 45.1 68.8 24.9 66.5 102.6 34.1 61.3 48.3 50.4 113.2 95.8 91.6 47.8 29.2 79.0 88.7 83.2 111.6 69.3 17.6 78.7 70.5 63.2 38.9 43.6 18.0 64.4 70.2 60.6 32.1 58.8 104.4 51.5 81.4 160.9 70.4 58.9 19.9 79.7 61.1 93.7 27.1 14.9 94.4 67.2 24.9 32.8 96.0 107.1 107.1 20.6 43.1 62.0 85.6 100.1 39.1 38.8 73.1 117.0 109.8 54.1 118.3 74.5 68.3 83.5 87.8 33.3 20.9 100.4 65.9 74.2 75.6 47.9 LARS2 "KIAA0028, LEURS, MGC26121, mtLeuRS" ENSG00000011376 "Leucyl-tRNA synthetase 2, mitochondrial" Q15031 3 45388561-45554726 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 28.7;Excitatory neurons: 35.4;Inhibitory neurons: 37.8;Oligodendrocyte precursor cells: 22.6;Oligodendrocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035951, HPA045450, HPA066085" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria Nucleoplasm "HPA035951: AB_10672997, HPA045450: AB_2679328, HPA066085: AB_2685612" "unprognostic (3.89e-1)" "unprognostic (3.89e-1)" "prognostic favorable (1.71e-4)" "unprognostic (3.02e-2)" "unprognostic (3.77e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-3)" "unprognostic (9.19e-2)" "unprognostic (6.13e-2)" "unprognostic (2.86e-1)" "unprognostic (4.98e-1)" "unprognostic (4.37e-2)" "prognostic favorable (1.32e-11)" "unprognostic (2.81e-1)" "unprognostic (5.74e-2)" "unprognostic (9.90e-2)" "unprognostic (9.07e-2)" 3.3 4.7 9.5 3.4 10.3 2.4 3.9 10.1 11.7 3.7 9.2 6.9 3.9 4.6 4.3 4.2 4.5 3.0 5.5 9.3 10.5 7.5 8.1 2.9 4.3 9.5 10.2 3.8 2.4 12.3 3.7 4.2 9.5 4.3 6.9 4.2 3.6 4.2 6.2 3.6 2.9 4.4 9.2 3.2 3.6 2.2 11.5 6.9 4.5 6.4 4.8 5.0 3.7 8.5 6.3 11.2 10.7 9.3 11.8 13.0 11.1 11.6 15.7 24.7 16.2 20.3 8.8 13.8 8.9 18.0 18.2 5.8 49.0 30.4 16.0 9.5 12.7 12.9 13.6 18.4 12.1 20.9 4.4 19.0 16.8 26.0 12.5 13.1 14.9 19.5 25.1 5.5 19.0 9.7 21.1 11.6 28.4 15.0 21.9 8.9 9.8 16.9 23.6 18.8 7.6 9.7 17.3 7.9 11.8 13.5 14.6 14.7 9.1 12.1 8.3 8.5 12.3 5.3 12.3 15.4 14.0 16.9 9.5 0.0 0.6 0.6 1.2 0.9 1.5 1.0 0.7 1.1 1.2 0.5 0.8 1.0 0.3 1.9 0.8 1.0 0.6 0.7 9.5 10.3 10.1 11.7 9.3 10.5 9.5 10.2 9.5 9.2 11.5 8.5 3.9 0.0 2.0 28.7 4.8 1.1 1.5 1.8 3.4 5.5 3.2 2.8 9.0 1.5 1.8 5.5 4.2 5.0 3.5 4.4 5.9 2.9 0.6 7.6 5.7 4.2 4.8 5.2 35.4 2.7 5.2 3.2 6.6 4.9 1.3 9.8 2.2 7.7 5.4 1.7 37.8 4.5 0.0 2.9 1.3 1.2 1.2 2.6 1.8 19.7 2.3 4.0 2.1 22.6 25.2 3.2 7.0 2.2 5.0 1.9 2.6 2.4 2.9 4.7 0.0 3.1 2.9 0.7 2.4 4.8 1.3 2.9 3.2 8.3 6.8 1.7 LAS1L "FLJ12525, Las1" ENSG00000001497 "LAS1 like ribosome biogenesis factor" Q9Y4W2 X 65438549-65534810 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044431, HPA061463" Supported Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Centriolar satellite, Cytosol" "HPA044431: AB_10965695, HPA061463: AB_2684530" "unprognostic (9.71e-2)" "unprognostic (1.62e-3)" "unprognostic (1.57e-1)" "unprognostic (1.47e-1)" "unprognostic (3.39e-2)" "unprognostic (2.38e-1)" "unprognostic (7.15e-3)" "unprognostic (2.83e-2)" "unprognostic (3.16e-1)" "unprognostic (2.76e-2)" "unprognostic (2.14e-1)" "unprognostic (5.06e-2)" "unprognostic (6.00e-3)" "unprognostic (1.26e-1)" "unprognostic (1.17e-3)" "unprognostic (2.00e-3)" "unprognostic (1.53e-1)" 21.5 19.1 36.9 11.4 37.8 16.0 21.2 35.6 53.7 27.1 34.0 26.4 5.8 23.1 6.8 20.0 25.5 6.3 18.6 34.8 34.8 19.1 19.6 17.4 13.1 36.3 37.1 29.9 21.2 12.2 17.5 8.9 36.8 22.7 8.1 9.4 18.8 11.9 19.3 25.4 18.5 10.3 38.1 22.5 20.0 33.6 37.1 12.8 20.5 6.3 14.0 24.2 21.4 37.8 44.1 63.6 36.3 28.5 12.4 16.1 29.1 28.5 14.9 42.8 36.4 30.4 31.3 95.0 31.3 17.8 28.7 31.3 63.9 39.6 50.6 25.6 52.3 32.2 53.2 32.4 16.6 95.9 26.8 17.8 28.7 40.5 25.6 15.1 26.0 46.1 80.3 71.3 25.5 51.8 62.4 53.6 52.6 49.8 63.1 56.2 67.4 79.9 24.7 17.9 24.6 32.9 51.3 26.0 20.1 25.8 19.5 44.6 22.2 26.4 50.9 73.2 44.4 23.7 37.7 94.6 28.1 92.5 13.6 17.7 17.7 11.2 20.1 24.0 21.3 23.9 18.6 23.5 24.2 26.4 23.2 19.8 2.0 22.9 19.3 19.1 21.7 21.0 36.9 37.8 35.6 53.7 34.8 34.8 36.3 37.1 36.8 38.1 37.1 37.8 15.5 12.8 22.3 23.2 21.6 18.2 21.4 24.8 9.1 34.9 12.7 13.6 9.2 21.5 27.0 3.7 29.2 32.8 13.3 6.9 15.6 27.9 58.0 17.5 20.0 17.2 16.7 18.1 19.6 26.6 31.4 16.8 11.7 12.9 18.3 26.0 8.9 14.8 16.3 45.4 17.7 9.4 18.3 8.5 13.4 148.2 17.4 11.7 10.6 8.4 18.1 16.1 12.3 13.0 12.5 21.4 7.7 15.4 26.3 23.5 10.2 14.3 26.7 34.2 13.1 21.8 22.8 24.1 19.1 17.8 18.6 17.8 17.5 22.3 14.1 14.8 LBR "DHCR14B, TDRD18" ENSG00000143815 "Lamin B receptor" Q14739 1 225401502-225428925 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "DNA-binding, Oxidoreductase, Receptor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 248.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062236 Enhanced Supported "Nuclear membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear membrane" "HPA062236: AB_2684721" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (2.14e-3)" "unprognostic (1.32e-2)" "unprognostic (7.96e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (7.30e-4)" "unprognostic (3.60e-2)" "unprognostic (1.11e-2)" "unprognostic (3.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (6.42e-2)" "unprognostic (2.08e-1)" "unprognostic (5.45e-1)" "unprognostic (8.32e-2)" "unprognostic (2.78e-1)" 28.6 9.1 8.8 53.2 9.7 95.7 17.1 9.3 11.9 27.3 9.2 61.4 40.7 47.0 44.4 29.7 31.8 21.7 10.0 8.5 10.1 19.4 47.3 19.2 81.6 12.0 9.8 19.4 16.9 5.6 6.5 27.6 11.2 23.8 46.2 5.3 11.1 36.7 9.8 13.8 39.9 41.4 10.2 41.5 28.2 20.5 9.5 105.5 11.8 12.8 70.7 32.3 23.0 13.1 122.2 42.0 154.9 69.3 64.8 39.7 77.3 31.2 39.2 65.0 69.0 87.2 207.2 248.4 66.6 32.8 38.6 88.8 114.2 32.9 98.5 142.2 107.1 61.4 40.4 81.5 39.9 274.7 105.5 34.3 21.3 58.9 52.0 33.1 82.9 117.4 189.6 164.6 44.4 16.3 254.9 156.6 140.6 121.8 14.2 164.9 141.4 234.0 75.6 52.7 40.6 53.4 52.7 39.6 26.6 68.2 53.3 181.0 50.5 17.6 91.7 49.3 115.9 56.6 83.0 274.5 24.3 120.5 61.2 83.6 44.3 67.3 43.6 31.6 50.9 39.0 43.5 48.8 38.4 39.5 42.4 52.9 211.4 41.3 25.2 21.5 61.9 69.8 8.8 9.7 9.3 11.9 8.5 10.1 12.0 9.8 11.2 10.2 9.5 13.1 98.1 28.9 36.4 13.4 86.4 27.0 33.4 17.3 21.6 4.5 11.9 11.0 8.5 48.6 34.4 31.3 6.2 40.5 98.3 33.4 5.9 23.6 1.2 31.5 31.0 53.1 27.0 248.9 10.5 19.8 23.9 29.0 29.0 53.9 10.1 24.0 48.5 73.6 44.4 11.8 14.3 43.0 12.2 88.5 18.1 3.4 33.8 71.7 26.6 19.7 56.0 11.6 82.4 37.2 34.1 20.6 24.6 32.4 74.0 32.9 19.3 26.0 26.0 10.4 39.5 13.9 46.6 21.0 26.7 68.4 35.5 11.1 81.3 13.2 73.8 36.7 LEMD3 MAN1 ENSG00000174106 "LEM domain containing 3" Q9Y2U8 12 65169583-65248355 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025078, HPA076986" Uncertain Supported "Nuclear membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear membrane" "HPA025078: AB_10601908, HPA076986: AB_2686821" "unprognostic (2.10e-2)" "unprognostic (6.83e-3)" "unprognostic (1.63e-3)" "unprognostic (1.76e-3)" "unprognostic (2.79e-1)" "unprognostic (1.04e-1)" "unprognostic (1.68e-3)" "unprognostic (7.22e-2)" "unprognostic (3.06e-2)" "unprognostic (4.16e-2)" "unprognostic (8.89e-2)" "unprognostic (2.43e-1)" "prognostic favorable (2.30e-4)" "unprognostic (4.37e-2)" "unprognostic (3.93e-1)" "unprognostic (1.35e-1)" "unprognostic (1.72e-1)" 9.3 7.3 6.6 10.5 8.0 20.8 10.6 12.2 9.4 8.6 6.9 10.4 9.6 12.2 8.8 8.1 9.3 6.9 7.2 8.5 6.3 9.6 9.5 9.3 13.5 6.0 6.9 11.9 9.8 14.7 5.3 7.2 6.4 9.4 10.0 16.6 9.3 7.7 8.7 8.0 9.4 8.3 6.9 11.4 9.7 15.6 6.9 13.6 10.6 9.6 12.3 8.9 8.1 7.7 19.7 10.9 17.1 17.2 11.8 13.6 11.7 22.4 12.0 11.0 9.5 13.7 12.4 53.2 14.1 13.9 8.5 25.8 18.5 16.0 15.9 12.8 21.4 21.7 10.2 10.5 9.0 33.4 15.1 9.9 16.9 13.1 17.6 15.5 13.1 14.6 28.9 24.6 15.6 11.5 17.5 17.3 23.5 8.9 11.1 40.6 16.8 26.8 13.8 21.4 17.8 10.9 22.5 22.7 14.0 16.4 22.6 26.0 18.1 13.4 14.3 12.7 15.7 17.5 17.7 32.3 11.2 16.1 16.8 1.0 0.7 1.4 1.5 0.6 2.0 1.8 2.0 2.0 1.0 1.9 1.9 2.1 0.8 1.6 0.9 2.1 1.9 0.7 6.6 8.0 12.2 9.4 8.5 6.3 6.0 6.9 6.4 6.9 6.9 7.7 21.7 38.5 21.0 29.7 29.0 32.1 19.4 10.4 14.8 20.1 15.3 11.3 14.7 8.6 13.5 11.0 18.8 8.0 32.7 20.2 0.0 10.3 2.1 16.3 18.0 17.4 14.9 16.8 50.0 13.1 4.6 18.5 13.3 19.8 22.2 12.5 14.6 13.3 6.5 16.8 58.2 13.7 12.2 13.7 16.4 3.2 15.8 16.4 17.8 49.6 16.1 20.3 17.5 53.3 52.7 14.6 14.5 12.4 23.6 18.9 7.8 4.3 19.3 21.5 6.6 23.5 19.2 43.3 35.3 17.6 39.1 14.4 21.9 13.7 11.8 22.9 LFNG SCDO3 ENSG00000106003 "LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q8NES3 7 2512529-2529177 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 74.4" "Cell type enhanced" "Detected in many" "dendritic cells: 40.3;Enteroendocrine cells: 87.4;monocytes: 38.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 37.7;OE19: 46.4;RH-30: 46.0;U-2 OS: 49.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069130 Approved Approved "Nuclear membrane,Golgi apparatus" "Intracellular and membrane" NA NA 880000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "Nuclear membrane" "HPA069130: AB_2686091" "unprognostic (4.58e-2)" "unprognostic (1.17e-2)" "unprognostic (2.52e-2)" "prognostic favorable (6.36e-4)" "unprognostic (1.85e-2)" "unprognostic (8.34e-2)" "unprognostic (4.15e-1)" "unprognostic (7.86e-2)" "unprognostic (1.91e-1)" "unprognostic (2.25e-1)" "unprognostic (8.55e-3)" "unprognostic (1.89e-1)" "unprognostic (5.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.09e-1)" "unprognostic (1.97e-2)" "unprognostic (2.28e-2)" 16.7 6.5 23.3 17.3 25.9 9.8 13.7 29.3 22.4 9.9 11.1 23.1 15.5 9.4 2.2 11.4 6.1 11.8 13.1 17.4 30.1 9.0 2.5 14.4 18.6 34.1 35.6 1.8 74.4 3.0 3.7 6.5 24.8 17.1 12.0 3.0 33.4 4.6 4.6 58.2 17.2 5.8 25.0 20.9 37.8 4.2 38.1 5.8 6.7 3.6 10.8 12.2 13.8 23.6 1.5 14.3 18.4 2.5 2.0 1.7 1.2 5.4 2.8 4.7 5.9 6.0 37.7 1.1 16.7 14.8 8.1 27.1 2.9 5.1 2.3 8.6 0.6 4.3 7.7 3.2 0.1 6.2 7.7 3.3 12.6 7.8 0.8 3.2 1.9 0.3 0.7 0.2 3.6 34.5 0.1 8.7 22.4 46.4 10.3 1.8 46.0 2.9 1.8 4.5 16.9 4.2 6.2 1.4 0.3 4.7 10.2 7.3 4.5 10.5 49.7 0.4 15.4 0.2 0.0 1.4 11.8 16.4 2.0 6.3 5.3 12.7 1.8 6.9 2.0 1.1 1.7 0.9 2.3 2.0 1.8 1.8 2.8 1.3 6.6 0.6 4.2 1.7 23.3 25.9 29.3 22.4 17.4 30.1 34.1 35.6 24.8 25.0 38.1 23.6 23.3 6.4 6.0 18.9 15.6 6.8 2.5 10.6 3.4 8.5 5.3 12.4 3.6 5.7 2.8 0.0 0.0 0.1 40.3 23.1 0.0 1.2 0.1 2.4 8.5 16.0 87.4 2.7 0.0 6.4 0.3 5.7 30.5 1.2 17.7 0.1 13.9 0.6 7.0 0.0 0.1 34.5 6.1 30.4 13.8 0.5 1.8 30.6 3.6 11.2 38.2 31.3 19.6 1.5 0.1 21.7 3.1 0.0 12.6 2.2 8.8 0.4 1.2 0.8 0.0 0.6 5.0 0.3 3.1 0.6 4.0 0.0 15.9 0.5 15.3 0.7 LGI4 ENSG00000153902 "Leucine rich repeat LGI family member 4" Q8N135 19 35124513-35142451 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 74.7;Distal enterocytes: 33.1;Muller glia cells: 95.5;Sertoli cells: 78.9;Smooth muscle cells: 104.4" "Group enriched" "Detected in many" 6 "glioma: 4.5;melanoma: 11.5;renal cancer: 13.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 27 "WM-115: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042116, HPA043556" Approved Approved "Golgi apparatus" "Secreted in brain" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA042116: AB_2677855, HPA043556: AB_2678550" "unprognostic (3.79e-1)" "unprognostic (6.13e-2)" "unprognostic (4.15e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-2)" "unprognostic (3.71e-2)" "unprognostic (2.12e-2)" "unprognostic (4.26e-2)" "unprognostic (4.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-1)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.84e-7)" "unprognostic (1.71e-2)" "unprognostic (4.47e-1)" "unprognostic (7.73e-2)" "unprognostic (7.13e-2)" 77.6 5.4 71.2 4.1 72.3 0.2 36.1 70.3 98.4 99.9 52.1 100.5 3.6 35.5 2.3 15.0 43.7 5.0 39.4 67.8 61.3 4.7 8.0 14.3 2.1 86.5 68.4 13.3 6.4 1.4 4.4 3.6 70.1 37.2 3.7 7.2 12.2 13.3 39.1 21.2 35.1 4.8 72.8 1.9 27.0 2.7 72.0 0.5 19.1 5.4 0.5 33.5 79.3 81.4 0.1 0.0 0.0 0.0 0.1 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.1 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 71.2 72.3 70.3 98.4 67.8 61.3 86.5 68.4 70.1 72.8 72.0 81.4 13.3 0.0 0.0 74.7 0.2 2.5 0.6 0.3 3.4 0.8 1.5 1.5 17.1 0.0 0.8 1.8 2.1 0.0 0.2 33.1 0.0 0.0 0.1 0.2 2.8 5.4 1.8 0.0 21.9 0.0 0.3 12.7 0.0 0.2 0.0 0.0 7.9 2.0 0.1 0.0 2.2 0.9 0.0 0.0 4.6 0.3 14.6 0.7 10.6 5.6 0.1 95.5 0.0 2.0 9.2 0.1 21.8 7.2 0.3 1.2 1.1 0.1 0.9 3.1 78.9 7.9 104.4 2.8 2.8 0.8 2.4 0.0 0.7 0.0 0.7 1.1 LHB "CGB4, hLHB, LSH-B" ENSG00000104826 "Luteinizing hormone subunit beta" P01229 19 49015980-49017091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 248 "pituitary gland: 4493.5" "Cell type enhanced" "Detected in some" "Early spermatids: 3.7;Late spermatids: 4.1;Pancreatic endocrine cells: 8.2;Syncytiotrophoblasts: 10.3" "Cancer enhanced" "Detected in many" "melanoma: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.7;HEK 293: 1.5;Hep G2: 1.4;K-562: 1.3;U-266/84: 2.0" "CAB022241, CAB022707, HPA038925" Enhanced Approved Cytosol "Secreted to blood" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "CAB022241: , CAB022707: , HPA038925: AB_2676272" "unprognostic (8.12e-2)" "unprognostic (3.59e-1)" "unprognostic (2.34e-3)" "unprognostic (1.41e-2)" "unprognostic (8.89e-2)" "unprognostic (6.25e-2)" "unprognostic (3.90e-3)" "unprognostic (5.69e-2)" "unprognostic (7.04e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (6.78e-4)" "unprognostic (2.47e-2)" "unprognostic (1.68e-3)" "unprognostic (1.38e-1)" "unprognostic (4.46e-1)" "unprognostic (9.52e-2)" "unprognostic (4.86e-2)" 1.0 5.1 0.2 0.0 0.1 0.0 0.6 0.4 0.3 0.5 0.0 0.5 1.3 0.5 0.0 1.3 0.6 0.0 0.9 0.1 0.2 1.4 1.9 0.9 0.2 0.2 0.1 0.6 18.0 0.6 4493.5 0.0 0.2 0.9 0.0 0.0 1.1 0.0 0.5 3.1 1.5 0.0 0.0 1.2 4.5 5.0 0.1 0.0 0.8 0.0 0.0 0.3 0.6 0.3 0.1 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.1 0.0 0.9 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 1.5 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 1.3 0.3 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.7 0.4 0.4 0.0 0.6 1.2 0.6 0.5 0.0 0.6 0.0 0.5 0.0 0.0 0.9 0.6 0.0 0.1 0.1 2.0 0.3 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.4 0.3 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.3 0.5 0.0 0.0 0.1 0.3 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.9 0.0 3.7 0.3 0.0 0.2 0.0 0.0 0.0 0.9 1.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 4.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.1 1.4 0.1 0.2 0.0 0.0 0.0 0.2 1.1 1.6 0.0 0.0 10.3 0.1 0.1 0.1 0.1 LIFR CD118 ENSG00000113594 "LIF receptor subunit alpha" P42702 5 38474668-38608354 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 318.9;Astrocytes: 376.8;Endothelial cells: 279.5;Hepatic stellate cells: 809.2;Oligodendrocytes: 275.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 88.0;HHSteC: 38.7;SCLC-21H: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 260000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.00e-3)" "unprognostic (2.53e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-3)" "unprognostic (8.80e-2)" "unprognostic (7.13e-2)" "unprognostic (1.11e-1)" "prognostic favorable (1.92e-4)" "unprognostic (1.78e-1)" "unprognostic (9.80e-2)" "unprognostic (2.73e-3)" "unprognostic (1.06e-1)" "prognostic favorable (1.40e-7)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" "unprognostic (1.65e-1)" 50.0 18.1 38.8 6.2 55.1 0.1 41.7 43.6 24.8 33.5 3.0 10.2 5.8 33.0 16.5 12.1 30.9 12.4 19.9 23.4 43.9 23.9 30.9 23.8 21.0 42.7 55.2 18.6 22.3 13.4 5.0 35.9 50.2 28.9 8.8 17.4 34.1 16.8 23.4 9.7 11.0 33.4 39.6 29.9 21.9 10.0 54.1 21.3 38.5 42.8 10.2 11.7 14.5 47.5 1.3 4.3 88.0 6.8 25.4 27.0 0.6 6.7 3.8 4.7 2.9 0.9 4.6 0.0 1.2 10.1 12.4 0.7 5.5 2.1 9.0 0.0 7.0 0.0 8.7 3.7 38.7 0.0 0.5 23.5 1.6 12.0 1.5 6.1 8.6 0.9 2.3 12.3 7.3 1.3 0.0 0.2 2.1 0.0 14.8 0.1 18.4 0.0 6.0 2.0 56.6 7.2 28.3 1.6 0.0 11.7 1.9 0.0 1.5 9.0 15.7 21.0 4.3 0.0 0.0 0.0 15.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.8 55.1 43.6 24.8 23.4 43.9 42.7 55.2 50.2 39.6 54.1 47.5 318.9 12.8 39.7 376.8 2.6 23.2 6.3 1.2 10.8 6.4 16.8 22.1 33.1 8.6 7.3 14.7 8.4 12.1 0.6 0.0 5.9 2.0 15.0 11.0 12.4 279.5 0.0 13.5 33.7 9.3 28.0 62.9 14.3 16.9 1.3 29.6 809.2 11.8 3.5 1.7 54.2 0.0 6.1 50.3 17.7 29.7 113.7 2.3 17.8 45.0 0.0 6.2 0.0 111.6 275.5 7.0 0.0 19.9 0.0 18.5 0.0 12.3 8.3 37.3 39.5 65.9 30.8 9.6 7.3 2.0 18.2 28.6 3.7 15.8 0.0 5.5 LIPH "LPDLR, mPA-PLA1, mPA-PLA1alpha, PLA1B" ENSG00000163898 "Lipase H" Q8WWY8 3 185506262-185552588 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.7;stomach 1: 48.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 144.2;Club cells: 135.5;Distal enterocytes: 312.3;Gastric mucus-secreting cells: 236.5;Intestinal goblet cells: 139.8;Proximal enterocytes: 226.1;Urothelial cells: 158.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 74.1;OE19: 17.2;RPTEC TERT1: 36.7;T-47d: 17.6;U-266/84: 18.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA049079 Approved "Secreted to blood" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA049079: AB_2680623" "unprognostic (4.50e-3)" "unprognostic (2.07e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (3.38e-1)" "unprognostic (1.01e-1)" "unprognostic (8.59e-2)" "unprognostic (1.44e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (7.88e-2)" "prognostic favorable (9.20e-5)" "unprognostic (1.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (4.21e-4)" "unprognostic (1.15e-1)" 0.3 0.3 0.3 2.8 0.6 0.1 3.8 0.1 0.6 2.8 6.9 36.3 11.1 0.2 7.1 14.7 1.1 12.3 0.4 0.4 1.6 7.8 0.4 18.3 0.1 0.1 0.1 0.5 5.5 0.0 0.3 0.1 0.1 6.8 37.7 0.2 13.2 2.0 0.5 7.4 11.8 0.6 0.0 0.4 48.2 2.7 0.2 0.3 0.2 0.1 3.0 12.2 4.3 0.1 10.3 13.5 0.1 0.1 0.0 0.2 2.9 0.3 0.0 0.3 0.3 1.3 74.1 0.0 7.5 0.2 2.9 3.6 5.6 0.1 0.4 0.1 1.6 1.8 1.8 1.4 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 5.4 0.1 0.0 1.3 0.5 0.1 0.7 17.2 1.1 0.0 0.0 1.0 36.7 9.2 0.0 0.0 1.1 12.2 0.3 0.6 17.6 0.3 0.0 0.1 1.1 0.1 0.2 1.2 18.9 0.1 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.3 0.3 0.6 0.1 0.6 0.4 1.6 0.1 0.1 0.1 0.0 0.2 0.1 0.1 144.2 38.5 2.0 0.8 0.8 16.3 76.5 0.6 0.7 55.6 12.7 0.4 94.4 135.5 68.0 0.0 0.2 1.0 312.3 1.9 57.8 0.2 7.0 0.5 1.8 22.2 0.0 1.7 24.9 0.1 1.1 236.5 5.7 7.0 36.0 1.1 0.3 0.0 0.0 0.9 139.8 38.7 0.3 0.3 0.1 0.0 2.4 16.0 0.0 0.8 0.3 2.1 2.5 0.4 60.4 102.7 0.0 0.3 72.8 226.1 1.6 105.6 0.9 0.0 0.1 5.5 1.1 0.3 6.9 2.0 0.3 0.8 12.0 102.1 158.0 LIPN "bA186O14.3, LIPL4" ENSG00000204020 "Lipase family member N" Q5VXI9 10 88759982-88779626 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase Ichthyosis "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "skin 1: 26.7" "Group enriched" "Detected in some" 4 "Macrophages: 7.5;monocytes: 2.5" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "classical monocyte: 2.9;eosinophil: 10.3;intermediate monocyte: 7.5;neutrophil: 5.4;non-classical monocyte: 8.5" "Group enriched" "Detected in many" 8 "granulocytes: 10.3;monocytes: 8.5" "Cell line enhanced" "Detected in single" "HL-60: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (2.01e-1)" "unprognostic (3.48e-1)" "unprognostic (1.13e-1)" "unprognostic (2.99e-1)" "unprognostic (1.08e-1)" "unprognostic (3.27e-1)" "unprognostic (1.07e-1)" "unprognostic (2.03e-2)" "unprognostic (9.75e-2)" "unprognostic (2.54e-2)" "unprognostic (4.40e-2)" "unprognostic (5.77e-3)" "unprognostic (1.65e-1)" 1.3 0.3 0.0 2.8 0.0 2.8 1.7 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.1 26.7 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 2.9 10.3 0.0 7.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 5.4 0.0 8.5 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.0 7.5 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 LMBR1 "ACHP, C7orf2, FLJ11665, ZRS" ENSG00000105983 "Limb development membrane protein 1" Q8WVP7 7 156668946-156893216 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 110.7;Inhibitory neurons: 128.7;Microglial cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016592 Approved Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol "HPA016592: AB_1852943" "unprognostic (8.81e-3)" "unprognostic (1.73e-2)" "unprognostic (9.49e-2)" "unprognostic (2.02e-1)" "unprognostic (3.77e-3)" "unprognostic (6.90e-2)" "unprognostic (1.30e-2)" "unprognostic (3.28e-1)" "unprognostic (1.21e-2)" "unprognostic (1.12e-2)" "unprognostic (1.69e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.44e-6)" "unprognostic (3.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.48e-1)" "unprognostic (7.10e-2)" 10.0 26.0 8.8 8.4 10.4 7.8 10.7 11.3 13.2 13.6 7.8 8.9 8.0 13.2 18.1 9.9 14.1 10.2 11.2 9.7 13.2 15.7 13.8 9.1 9.4 11.0 10.0 16.5 8.8 38.0 7.5 10.1 11.2 12.2 10.3 14.3 8.4 10.7 6.7 8.4 9.3 13.2 8.9 7.6 11.9 17.7 10.6 11.8 17.6 11.4 8.7 11.9 6.0 8.5 26.9 20.6 27.5 33.4 21.1 24.0 16.6 14.5 20.5 14.2 16.8 15.4 42.4 25.3 27.6 19.7 27.3 20.4 28.4 28.9 29.1 19.5 25.5 19.1 11.6 19.7 13.6 23.8 13.6 19.3 27.0 20.4 27.3 22.8 29.6 23.4 35.7 23.8 26.9 24.3 25.1 20.5 29.4 30.4 18.7 13.1 18.1 31.6 22.8 25.1 26.1 51.9 20.4 27.8 15.6 17.8 19.1 14.3 38.4 25.1 9.3 82.7 19.6 25.6 22.6 24.0 40.0 30.2 16.4 1.8 0.7 1.0 0.7 0.4 1.4 0.6 1.2 1.2 1.3 0.8 1.5 1.0 0.6 0.2 0.7 0.9 0.9 0.6 8.8 10.4 11.3 13.2 9.7 13.2 11.0 10.0 11.2 8.9 10.6 8.5 25.6 3.2 8.1 54.5 23.7 10.5 13.7 9.9 43.3 11.5 12.8 8.5 17.1 11.5 7.2 12.9 2.1 14.3 8.4 8.6 5.9 11.0 7.4 17.0 8.6 24.8 8.3 17.4 110.7 10.1 5.6 15.2 23.0 15.7 5.7 43.2 9.3 19.2 10.2 8.4 128.7 9.9 10.2 10.1 8.0 9.7 10.5 9.3 7.2 99.3 8.2 6.7 3.1 72.4 70.4 12.6 6.1 8.6 23.4 20.0 9.7 12.2 9.7 10.9 0.0 11.9 11.0 18.0 28.7 30.9 12.8 23.1 18.0 26.2 11.1 16.6 LMNA "CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1" ENSG00000160789 "Lamin A/C" P02545 1 156082573-156140081 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cardiomyopathy, Charcot-Marie-Tooth disease, Congenital muscular dystrophy, Disease variant, Emery-Dreifuss muscular dystrophy, Limb-girdle muscular dystrophy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 1533.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 85.1;T-reg: 83.2" "Group enriched" "Detected in all" 8 "dendritic cells: 85.1;granulocytes: 23.9;T-cells: 83.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004022, HPA006523, HPA006660" Supported Supported "Nuclear speckles" NA NA 5700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "CAB004022: AB_2136278, HPA006523: , HPA006660: AB_1079231" "unprognostic (2.22e-2)" "unprognostic (1.89e-1)" "unprognostic (1.04e-2)" "unprognostic (5.75e-2)" "unprognostic (7.43e-3)" "unprognostic (1.47e-1)" "unprognostic (5.23e-3)" "unprognostic (3.27e-2)" "unprognostic (8.33e-2)" "unprognostic (5.90e-2)" "unprognostic (5.10e-2)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "unprognostic (2.89e-1)" "unprognostic (3.08e-2)" "unprognostic (1.44e-2)" 280.2 174.8 17.6 64.9 27.1 58.1 231.5 24.1 20.6 221.7 33.0 183.3 72.8 271.4 14.5 256.2 173.8 92.1 221.7 15.8 23.1 120.9 93.2 188.5 18.2 30.3 25.2 178.2 81.8 21.3 76.9 53.0 26.1 125.3 38.2 4.7 176.1 42.8 190.0 364.3 136.8 78.8 21.0 84.1 160.6 61.9 30.9 15.3 147.4 23.8 22.9 168.7 217.6 41.8 518.8 269.7 26.2 72.4 119.5 238.7 169.4 607.3 379.6 221.3 146.8 68.3 311.9 2.8 338.7 417.9 94.6 515.4 31.4 227.8 70.3 188.6 50.8 175.4 168.4 130.8 124.0 25.7 412.9 133.0 92.0 154.8 134.7 120.2 207.5 0.7 82.8 21.9 205.8 193.1 1.0 67.8 32.1 202.9 706.0 1.6 195.9 137.7 128.9 105.6 33.8 114.9 414.3 154.2 427.4 56.2 230.1 74.2 727.9 241.6 233.0 389.1 393.3 39.5 10.5 4.9 449.2 24.8 760.4 23.9 8.3 0.4 2.8 2.1 2.5 2.4 17.8 7.3 85.1 0.2 0.2 0.7 2.1 3.7 0.2 0.3 83.2 14.6 17.6 27.1 24.1 20.6 15.8 23.1 30.3 25.2 26.1 21.0 30.9 41.8 353.5 262.8 350.0 16.0 179.1 610.5 1235.3 446.2 531.6 7.2 542.5 374.9 94.1 191.6 320.3 161.8 47.9 478.8 239.8 614.1 109.5 429.3 38.6 215.4 209.4 386.0 431.5 70.4 9.9 360.2 387.8 622.1 505.1 270.5 1181.8 145.5 277.7 103.1 343.0 13.5 15.1 601.2 177.0 60.6 1533.4 45.4 288.6 409.0 859.2 10.3 20.4 37.2 3.1 17.1 20.1 513.0 384.1 287.3 331.3 340.6 262.6 125.0 170.5 17.8 203.8 1028.4 766.8 107.4 42.2 404.1 602.4 680.9 472.3 111.6 513.8 942.6 LMX1B NPS1 ENSG00000136944 "LIM homeobox transcription factor 1 beta" O60663 9 126613928-126701032 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.2;salivary gland: 18.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.3;Breast myoepithelial cells: 7.2;Cardiomyocytes: 1.9;Early spermatids: 1.6;Spermatogonia: 2.1" "Cancer enriched" "Detected in some" 14 "breast cancer: 12.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.5;HEK 293: 3.6;MCF7: 11.9;OE19: 10.4;T-47d: 8.1" "Region enhanced" "Detected in some" "pons and medulla: 2.3" "Region enhanced" "Detected in many" "midbrain: 5.0" "HPA073716, HPA075656" Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA073716: AB_2686630, HPA075656: " "unprognostic (4.17e-1)" "unprognostic (4.72e-2)" "unprognostic (2.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.73e-1)" "unprognostic (1.50e-4)" "unprognostic (1.86e-1)" "unprognostic (2.20e-2)" "unprognostic (3.41e-1)" "unprognostic (2.26e-1)" "unprognostic (1.34e-2)" "unprognostic (3.51e-3)" "unprognostic (1.63e-5)" "unprognostic (1.69e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-6)" "unprognostic (1.13e-2)" 0.6 0.0 0.1 0.0 0.1 0.1 4.1 0.1 5.6 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.0 1.0 3.6 0.0 0.1 0.0 3.8 9.2 0.0 0.2 1.1 0.2 0.0 3.3 0.0 0.0 0.0 18.5 0.0 0.1 2.1 0.1 0.0 6.8 0.0 0.1 1.4 2.6 0.0 0.4 0.0 0.0 0.0 0.0 0.5 1.2 0.6 0.3 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.3 0.0 2.5 0.6 3.5 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.5 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 11.9 0.0 0.0 0.0 10.4 0.0 0.0 2.4 0.0 0.0 0.1 0.0 1.1 0.3 0.0 0.2 0.1 8.1 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 5.6 1.0 1.0 3.8 9.2 3.3 6.8 2.6 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 8.3 7.2 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 1.6 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 LNPK "KIAA1715, LNP, LNP1, Ul" ENSG00000144320 "Lunapark, ER junction formation factor" Q9C0E8 2 175923882-176002839 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 19.3;Endometrial stromal cells: 24.6;Hofbauer cells: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-138 MG: 159.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014205 Approved Supported "Nucleoplasm,Endoplasmic reticulum" NA NA 15000 "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" Nucleoplasm "HPA014205: AB_2234186" "unprognostic (4.93e-2)" "unprognostic (3.35e-2)" "unprognostic (1.20e-1)" "unprognostic (7.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-2)" "unprognostic (8.73e-2)" "unprognostic (1.27e-1)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (3.13e-1)" "unprognostic (4.17e-3)" "unprognostic (1.63e-1)" "unprognostic (9.27e-2)" "unprognostic (2.35e-3)" "unprognostic (3.43e-2)" 13.5 8.9 6.3 7.7 10.1 30.1 9.8 10.2 8.7 12.0 4.2 12.0 7.6 8.6 6.2 13.1 6.3 7.7 12.2 7.6 13.2 8.2 14.4 6.7 7.2 11.3 9.2 10.7 5.5 15.6 6.0 6.1 14.1 10.1 10.2 24.1 6.4 8.2 34.1 12.1 7.5 9.6 11.3 5.9 7.8 24.5 9.3 14.0 8.8 26.8 7.9 7.6 9.2 19.0 24.5 12.3 28.3 40.1 58.5 36.1 14.3 70.8 33.7 32.2 45.1 17.0 28.2 24.4 39.4 31.5 42.3 26.5 26.9 18.9 44.6 37.5 27.4 27.6 14.8 15.2 13.8 47.2 32.9 29.9 17.5 31.4 15.4 26.4 6.0 19.3 28.9 31.5 44.9 16.0 31.4 18.8 9.2 24.9 23.4 31.3 28.6 18.0 13.6 22.2 32.6 32.9 31.3 17.5 24.1 26.6 26.2 15.4 9.2 159.0 23.6 53.9 33.7 18.5 36.6 20.3 49.4 15.2 30.4 3.7 4.2 7.9 4.9 4.8 5.8 4.3 4.2 5.4 3.9 3.3 4.2 6.7 3.4 6.5 4.5 4.4 7.8 3.4 6.3 10.1 10.2 8.7 7.6 13.2 11.3 9.2 14.1 11.3 9.3 19.0 10.8 19.2 13.6 0.0 4.4 0.0 0.0 0.0 0.0 0.0 19.3 15.0 0.0 0.0 6.2 16.5 0.0 5.7 14.5 0.0 5.9 14.0 0.0 10.1 24.6 3.5 0.0 0.0 0.0 9.6 17.3 12.8 0.0 12.7 11.4 10.6 0.0 0.0 24.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 3.3 0.0 0.0 9.1 8.7 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 8.3 7.2 12.0 0.0 0.0 LONP1 "hLON, LonHS, PIM1, PRSS15" ENSG00000196365 "Lon peptidase 1, mitochondrial" P36776 19 5691834-5720572 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Hydrolase, Protease, Serine protease" "Cataract, Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 196.2" "Cell type enhanced" "Detected in all" "Theca cells: 85.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002034, HPA002192" Supported Enhanced Nucleoplasm,Mitochondria No No 7900 "Cluster 6: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA002034: AB_2756304, HPA002192: AB_1079695" "unprognostic (6.52e-2)" "unprognostic (1.12e-1)" "unprognostic (2.43e-1)" "unprognostic (2.43e-2)" "unprognostic (2.84e-1)" "unprognostic (2.38e-1)" "unprognostic (1.66e-3)" "unprognostic (5.56e-2)" "unprognostic (2.71e-1)" "unprognostic (7.57e-2)" "unprognostic (4.04e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-2)" "unprognostic (1.09e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (2.11e-1)" 30.4 196.2 31.5 22.2 32.7 23.7 27.2 34.6 42.8 24.4 39.9 27.9 22.6 25.2 14.1 27.7 22.6 15.4 76.0 30.8 35.7 43.2 79.1 25.6 24.1 37.6 35.8 26.6 38.2 35.2 41.5 18.5 37.9 26.4 13.2 13.0 30.8 16.6 69.3 28.9 25.5 14.7 30.8 29.5 33.7 24.2 37.2 17.5 34.6 40.7 14.5 28.2 22.4 33.0 108.4 111.0 35.6 114.0 41.4 29.2 110.4 67.2 52.7 71.0 86.0 96.3 37.7 134.3 91.4 70.6 68.0 45.0 92.1 81.1 34.2 80.0 78.0 74.5 97.5 127.6 190.4 169.7 74.9 55.0 114.6 67.5 132.6 34.1 57.5 183.9 200.9 259.4 33.0 71.8 85.5 101.6 127.6 43.6 143.1 89.4 50.9 146.6 39.3 63.9 94.2 94.1 59.4 85.2 242.2 24.9 50.3 211.9 41.2 36.0 39.2 100.7 99.2 272.3 182.6 121.4 161.7 185.0 66.2 4.5 2.4 0.5 3.4 3.7 2.3 4.0 3.1 3.4 2.6 3.7 3.8 2.6 0.3 2.7 1.5 3.9 2.7 1.7 31.5 32.7 34.6 42.8 30.8 35.7 37.6 35.8 37.9 30.8 37.2 33.0 12.6 6.4 13.1 18.3 14.1 8.3 11.1 14.9 11.4 26.9 14.2 12.7 19.8 15.7 14.3 27.6 6.2 28.8 8.4 40.1 46.9 33.9 6.5 24.0 16.3 15.3 11.4 17.1 13.5 28.0 31.9 13.3 29.6 25.6 5.7 51.1 11.4 47.0 30.8 21.9 17.4 26.4 22.4 14.6 8.6 6.3 12.8 16.4 14.2 9.4 17.8 24.9 8.2 10.6 15.7 26.0 16.8 17.3 17.6 16.8 27.5 50.2 17.0 26.5 19.7 17.9 24.7 12.0 14.4 11.0 10.7 35.0 10.7 85.0 35.1 11.4 LORICRIN LOR ENSG00000203782 "Loricrin cornified envelope precursor protein" P23490 1 153259687-153262124 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Keratinization "Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "skin 1: 1842.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "melanoma: 45.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 92 "HDLM-2: 35.2" "HPA076123, HPA077266" Enhanced NA NA 1800000 "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA076123: AB_2732302, HPA077266: AB_2732338" "unprognostic (1.97e-2)" "unprognostic (1.93e-2)" "unprognostic (4.16e-2)" "prognostic favorable (8.53e-4)" "unprognostic (1.65e-1)" "unprognostic (2.69e-1)" "unprognostic (1.61e-1)" "unprognostic (3.41e-1)" "unprognostic (1.47e-1)" "unprognostic (3.03e-1)" "unprognostic (1.02e-2)" 1.1 0.2 0.5 0.2 0.4 0.0 24.2 0.2 0.4 0.8 0.0 0.5 0.0 0.2 0.0 0.7 0.0 0.0 0.7 0.4 0.9 0.2 0.8 0.4 0.1 0.7 0.5 0.5 0.6 0.0 0.2 0.0 0.5 0.2 0.0 0.0 1.7 0.0 10.9 1842.9 0.4 0.0 0.5 0.4 0.3 0.5 1.0 0.6 0.3 0.0 1.8 0.1 21.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.2 0.4 0.4 0.9 0.7 0.5 0.5 0.5 1.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LPAR6 "P2RY5, P2Y5" ENSG00000139679 "Lysophosphatidic acid receptor 6" P43657 13 48389567-48444704 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 266.1;Basal squamous epithelial cells: 327.2;Early spermatids: 334.0;Langerhans cells: 703.7;Late spermatids: 321.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 21.6;HUVEC TERT2: 35.3;MOLT-4: 20.0" "Low region specificity" "Detected in all" HPA028934 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" "HPA028934: AB_2672833" "unprognostic (1.19e-1)" "unprognostic (4.10e-1)" "unprognostic (8.82e-2)" "unprognostic (9.30e-3)" "unprognostic (2.31e-1)" "unprognostic (5.57e-2)" "unprognostic (7.40e-2)" "prognostic favorable (6.22e-4)" "unprognostic (1.07e-2)" "unprognostic (8.00e-2)" "unprognostic (2.63e-1)" "unprognostic (2.46e-1)" "prognostic unfavorable (3.60e-4)" "unprognostic (6.54e-2)" "unprognostic (3.81e-2)" "unprognostic (2.09e-2)" "unprognostic (1.94e-2)" 41.0 26.5 14.5 26.8 14.7 6.1 43.0 15.2 27.1 41.9 18.3 22.1 15.0 28.7 39.5 81.8 22.2 35.5 24.9 14.0 15.8 26.2 23.2 34.6 45.6 19.0 16.4 14.9 8.7 9.7 15.9 77.7 18.0 60.7 27.6 5.8 59.7 32.2 9.0 33.9 21.7 27.1 18.2 40.2 21.6 8.1 16.7 36.4 24.3 20.8 41.1 40.8 75.1 21.0 0.1 2.1 21.6 0.1 7.0 8.6 0.2 4.5 12.7 0.9 2.5 0.0 6.4 0.0 0.1 4.9 0.0 12.7 0.6 7.2 0.4 0.0 4.3 0.2 0.2 15.9 4.6 0.1 0.1 11.5 12.4 0.5 7.0 0.0 35.3 7.0 0.0 0.3 4.2 0.0 20.0 6.3 8.6 0.4 5.9 16.9 0.0 0.2 5.9 13.1 0.0 0.1 0.0 0.1 4.5 13.2 2.2 0.1 9.1 2.4 0.0 0.2 1.1 0.0 0.0 0.0 0.7 1.1 7.8 1.3 71.9 0.3 24.6 112.0 13.6 1.2 70.0 29.4 26.0 0.5 49.3 15.6 5.9 6.9 103.6 1.1 83.9 58.2 14.5 14.7 15.2 27.1 14.0 15.8 19.0 16.4 18.0 18.2 16.7 21.0 266.1 3.2 9.7 4.9 5.8 120.6 196.3 155.7 327.2 1.7 30.5 30.5 5.8 17.2 76.2 5.5 0.0 0.8 22.2 4.9 0.0 10.4 334.0 10.1 20.7 140.1 21.4 8.8 1.8 4.1 0.8 23.6 16.8 12.8 7.6 5.8 136.0 2.9 82.9 0.0 1.8 4.9 42.7 74.0 703.7 321.7 22.7 111.9 49.8 177.1 76.4 11.3 18.6 5.0 2.0 6.7 4.1 15.8 6.3 107.1 3.0 25.5 49.4 1.5 13.1 5.4 13.3 2.5 1.7 182.7 142.9 0.8 52.3 14.0 9.6 143.5 LRP2 "DBS, gp330" ENSG00000081479 "LDL receptor related protein 2" P98164 2 169127109-169362534 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Hearing, Neurogenesis, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 70.5;kidney: 34.8;parathyroid gland: 44.7;retina: 29.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Cytotrophoblasts: 63.2;Oligodendrocytes: 300.1;Proximal tubular cells: 283.9" "Cancer enhanced" "Detected in many" "renal cancer: 29.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "AF22: 39.4;CACO-2: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA005980, HPA064792" Enhanced Approved Vesicles,Mitochondria No NA 74000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Mitochondria" "HPA005980: AB_1079278, HPA064792: AB_2685353" "unprognostic (1.87e-1)" "unprognostic (1.04e-3)" "unprognostic (1.32e-3)" "unprognostic (3.65e-3)" "unprognostic (3.18e-2)" "unprognostic (1.60e-2)" "unprognostic (1.64e-3)" "unprognostic (2.99e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (4.09e-2)" "unprognostic (4.38e-1)" "prognostic favorable (3.43e-5)" "unprognostic (1.37e-1)" "unprognostic (4.21e-1)" "unprognostic (2.44e-2)" "unprognostic (1.62e-2)" 1.5 0.0 5.5 0.0 23.4 0.1 9.6 18.9 13.5 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.2 7.5 14.6 34.8 0.3 1.2 0.0 30.5 17.5 0.0 0.0 44.7 0.1 7.5 31.9 0.0 0.0 29.3 0.9 0.0 0.1 0.1 0.0 0.0 14.5 0.0 0.0 0.2 18.7 0.0 17.3 0.0 0.0 0.0 0.0 70.5 0.0 0.0 39.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 64.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 23.4 18.9 13.5 7.5 14.6 30.5 17.5 31.9 14.5 18.7 70.5 0.2 6.4 43.7 1.0 3.0 0.3 0.2 0.0 0.0 2.8 22.9 15.1 2.1 2.8 2.5 3.7 87.6 63.2 0.2 0.0 17.6 0.0 3.1 0.1 0.1 0.5 0.0 0.0 1.8 0.0 2.2 1.8 0.0 0.1 2.5 0.0 0.0 0.8 5.1 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 2.5 0.0 1.9 0.0 33.1 0.0 1.5 300.1 0.0 0.0 0.0 0.0 0.0 0.0 283.9 2.2 19.5 0.0 0.0 0.3 0.1 0.8 0.0 0.0 23.1 1.7 0.0 0.0 0.2 LRP4 "CLSS, LRP-4, MEGF7, SOST2" ENSG00000134569 "LDL receptor related protein 4" O75096 11 46856717-46918642 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 46.7;skin 1: 31.6" "Cell type enhanced" "Detected in many" "Astrocytes: 123.1;Cone photoreceptor cells: 41.7;Distal enterocytes: 31.1;Oligodendrocyte precursor cells: 137.2;Oligodendrocytes: 31.3" "Group enriched" "Detected in all" 4 "colorectal cancer: 12.2;endometrial cancer: 8.6;glioma: 13.2;testis cancer: 15.6;thyroid cancer: 28.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 21.3;SuSa: 16.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011934, HPA012300" Approved Uncertain Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli, Mitochondria" "HPA011934: AB_1853286, HPA012300: AB_1853288" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.86e-1)" "unprognostic (1.33e-2)" "unprognostic (4.39e-2)" "unprognostic (9.73e-3)" "unprognostic (5.29e-4)" "unprognostic (8.61e-2)" "unprognostic (2.29e-2)" "unprognostic (2.77e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (7.59e-2)" "unprognostic (7.95e-2)" "unprognostic (2.76e-2)" "unprognostic (9.90e-3)" "unprognostic (6.79e-2)" 0.7 1.4 23.3 0.9 30.5 0.0 1.5 19.1 21.3 2.3 0.0 4.8 3.4 1.6 0.9 1.8 1.4 2.0 6.9 24.2 16.0 0.7 0.2 2.9 0.1 46.7 23.0 4.6 2.2 5.6 2.6 2.6 19.8 2.1 3.4 7.9 1.7 2.3 4.4 31.6 4.9 1.5 21.3 3.9 7.8 1.1 30.9 1.5 2.4 7.7 0.3 0.9 1.4 25.6 0.1 9.6 21.3 6.5 13.4 3.7 4.9 1.0 1.9 2.8 3.2 2.8 0.0 0.0 1.4 11.4 3.1 3.9 12.0 7.5 2.2 0.0 10.3 1.0 3.8 6.8 2.8 0.1 1.9 4.5 4.2 4.4 1.1 2.5 2.5 2.6 0.9 0.0 1.6 0.8 0.2 0.3 11.9 0.0 0.9 1.6 7.3 0.0 0.3 2.8 0.1 14.2 1.2 0.0 3.4 16.2 0.3 0.5 0.2 5.7 3.5 6.5 2.1 0.0 0.0 0.4 4.3 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 30.5 19.1 21.3 24.2 16.0 46.7 23.0 19.8 21.3 30.9 25.6 0.2 0.0 1.9 123.1 0.0 8.2 2.7 2.4 10.8 0.5 0.3 1.9 6.2 0.0 1.9 1.8 41.7 2.6 0.0 31.1 1.9 0.0 0.5 1.0 4.7 1.0 0.0 0.0 19.7 0.4 0.4 5.0 3.1 4.4 5.1 1.6 1.8 0.4 0.2 0.0 18.6 2.8 0.0 0.0 0.4 0.0 1.8 0.2 1.8 15.0 0.6 9.3 0.0 137.2 31.3 0.3 3.0 1.2 0.0 1.0 8.0 0.3 1.1 2.7 0.0 12.4 0.9 0.2 0.8 2.3 10.9 1.4 0.2 8.4 3.3 0.8 LRP5 "BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2" ENSG00000162337 "LDL receptor related protein 5" O75197 11 68312591-68449275 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Disease variant, Osteogenesis imperfecta, Osteopetrosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 129.7" "Cell type enhanced" "Detected in many" "Granulosa cells: 84.7;Proximal enterocytes: 54.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 161.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013001, HPA030505" Approved NA NA 1500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "CAB013001: AB_2533267, HPA030505: AB_2673505" "unprognostic (3.67e-1)" "unprognostic (2.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.13e-2)" "unprognostic (3.33e-1)" "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (2.94e-2)" "unprognostic (9.63e-2)" "unprognostic (2.54e-1)" "unprognostic (2.78e-1)" "unprognostic (6.82e-2)" "prognostic favorable (3.55e-10)" "unprognostic (2.28e-2)" "unprognostic (1.62e-2)" "unprognostic (1.58e-1)" "unprognostic (7.42e-2)" 35.6 37.6 9.6 6.9 11.4 3.2 36.9 10.9 11.2 26.0 44.4 32.4 43.1 30.6 4.1 18.5 26.4 21.0 35.7 8.6 9.2 30.3 129.7 23.3 4.3 12.6 11.9 27.9 34.9 11.6 15.9 23.2 11.7 25.1 11.2 1.7 73.3 20.0 10.4 19.3 44.8 11.1 10.1 8.9 31.8 5.6 10.2 9.6 33.4 7.3 2.6 24.5 19.4 10.6 30.9 103.6 11.0 25.4 20.6 11.4 47.0 14.0 12.1 8.3 7.5 58.7 104.2 0.0 87.5 18.2 35.1 38.9 9.9 37.3 1.2 5.0 22.6 21.6 52.8 77.2 20.8 15.8 2.0 16.4 12.5 0.4 13.6 22.3 23.7 18.8 38.5 1.6 6.0 69.5 23.7 62.7 19.6 161.2 41.7 29.6 30.1 49.7 14.2 82.1 10.6 21.6 37.0 49.4 41.0 5.3 34.6 36.2 31.5 0.2 9.0 11.6 15.8 6.3 0.8 6.3 0.0 9.7 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 9.6 11.4 10.9 11.2 8.6 9.2 12.6 11.9 11.7 10.1 10.2 10.6 37.4 6.4 5.4 17.0 1.1 9.2 8.5 11.3 10.8 0.2 24.4 23.2 5.6 21.5 9.6 7.3 0.0 49.0 0.0 42.7 0.0 11.7 1.1 19.2 6.5 20.4 17.5 10.7 1.1 9.8 6.7 10.6 30.5 12.5 1.3 84.7 31.8 52.5 8.4 0.0 5.7 43.0 18.3 3.2 4.6 1.0 3.1 1.7 1.8 11.2 1.3 8.8 0.0 13.0 5.2 12.5 32.4 9.8 5.7 13.0 54.9 8.5 4.8 0.1 6.6 18.5 10.9 0.8 7.3 7.6 5.3 24.8 1.0 1.3 25.1 13.8 LTBP2 "C14orf141, LTBP3" ENSG00000119681 "Latent transforming growth factor beta binding protein 2" Q14767 14 74498183-74612378 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Heparin-binding" "Disease variant, Dwarfism, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 60.6;Fibroblasts: 59.5;Peritubular cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 240.8;HUVEC TERT2: 129.1;LHCN-M2: 129.4;TIME: 564.5" "Group enriched" "Detected in some" 10 "cerebellum: 5.3;olfactory bulb: 2.4" "Region enhanced" "Detected in many" "olfactory bulb: 15.4" HPA003415 Approved Approved Nucleoplasm "Secreted to extracellular matrix" NA NA 14000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA003415: AB_1079284" "unprognostic (1.24e-1)" "unprognostic (3.09e-2)" "unprognostic (5.10e-2)" "unprognostic (3.92e-3)" "unprognostic (2.08e-3)" "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (4.43e-2)" "unprognostic (1.08e-1)" "unprognostic (1.61e-1)" "unprognostic (2.80e-2)" "unprognostic (3.77e-1)" "unprognostic (1.98e-3)" "unprognostic (2.22e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.94e-4)" 34.2 4.0 1.1 15.2 2.9 0.6 24.4 4.1 5.6 66.2 9.5 6.6 3.1 22.5 23.9 10.7 11.7 33.1 45.4 1.2 1.1 4.1 2.1 64.9 8.3 2.2 1.1 39.4 8.7 9.6 7.3 28.0 1.4 15.7 2.6 2.3 26.7 19.6 13.6 12.6 6.9 16.0 2.2 3.9 8.5 5.4 1.9 3.1 53.0 21.4 6.1 14.2 21.6 1.0 2.5 4.9 1.2 0.2 36.9 67.7 0.2 47.4 16.2 9.2 5.7 0.0 17.4 0.4 13.8 240.8 4.1 4.8 0.2 17.7 3.8 0.2 0.8 0.8 2.2 2.1 8.8 0.1 0.6 70.2 7.7 50.7 29.1 68.9 129.1 0.1 0.2 0.1 129.4 1.1 0.1 0.3 0.3 0.2 4.5 0.5 1.1 0.1 11.3 6.7 1.0 3.3 33.1 0.1 1.1 3.4 1.1 0.2 564.5 3.3 54.0 17.0 18.0 0.7 0.7 0.1 13.1 0.3 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 2.9 4.1 5.6 1.2 1.1 2.2 1.1 1.4 2.2 1.9 1.0 3.8 0.0 2.2 2.3 0.1 5.6 15.1 13.0 13.1 2.1 1.9 60.6 6.4 0.0 6.1 0.0 0.0 0.5 1.2 0.1 5.9 1.4 1.2 0.5 7.9 6.5 0.0 5.7 1.1 0.4 0.3 59.5 1.5 0.9 1.3 1.9 9.3 0.4 4.2 3.3 0.7 0.0 20.3 0.3 5.8 5.8 16.4 3.7 0.0 22.5 0.1 0.4 0.0 1.0 0.3 4.4 0.0 82.4 0.3 10.7 0.0 0.0 0.3 1.0 6.6 3.2 10.8 2.8 3.8 5.2 1.0 1.2 0.9 2.2 0.1 2.1 LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 327.1;Leydig cells: 972.3;Peritubular cells: 624.4;Skeletal myocytes: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 120.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" NA NA 9700000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" 138.5 48.5 11.3 22.3 10.9 8.3 98.8 1.7 13.3 334.6 9.6 144.5 59.2 309.6 44.7 100.6 246.8 39.3 401.9 10.7 14.2 64.7 37.4 242.5 24.8 16.2 10.3 315.2 37.2 22.6 75.9 38.3 16.4 253.6 38.2 3.7 82.8 126.3 63.0 73.0 135.4 74.4 11.3 80.5 125.3 78.5 14.2 12.9 173.2 156.7 14.0 188.6 374.5 15.3 19.8 21.3 41.7 56.5 15.1 16.0 6.6 7.7 24.9 7.8 6.4 6.4 43.8 22.4 34.9 13.1 12.4 26.3 10.6 26.8 2.6 61.0 3.3 7.3 53.7 2.4 49.4 3.0 23.1 19.9 21.7 15.6 27.8 41.0 4.9 21.6 46.7 120.3 1.9 19.7 3.1 1.3 4.9 56.1 24.9 51.9 1.1 35.6 3.9 1.7 1.8 17.4 28.3 21.5 7.4 6.4 11.9 11.3 20.4 1.3 81.4 2.6 16.7 26.8 24.9 7.1 35.1 28.5 20.4 0.0 1.5 0.4 8.1 2.4 5.5 3.5 7.7 6.5 2.7 2.0 3.2 3.4 0.3 3.0 1.3 5.0 5.5 2.3 11.3 10.9 1.7 13.3 10.7 14.2 16.2 10.3 16.4 11.3 14.2 15.3 84.7 6.4 14.1 2.0 11.6 57.6 30.9 62.8 56.3 60.4 13.0 18.2 15.5 17.2 18.5 22.0 0.0 1.5 12.7 38.2 1.9 6.3 11.1 14.8 154.7 29.9 4.2 12.4 8.1 4.7 2.6 327.1 37.2 24.2 10.2 13.5 102.4 3.3 7.5 40.4 11.3 42.2 6.1 6.4 39.6 39.0 972.3 13.9 58.7 15.0 9.5 3.5 16.5 2.0 14.0 6.9 16.6 624.4 16.5 23.6 97.7 0.3 7.1 3.2 59.2 229.2 52.8 50.7 36.3 38.2 29.1 2.6 24.9 10.2 36.4 27.2 LZTR1 "BTBD29, LZTR-1" ENSG00000099949 "Leucine zipper like transcription regulator 1" Q8N653 22 20982269-20999032 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067852, HPA068772, HPA071248" Approved Approved Nucleoplasm,Centrosome,Cytosol No No "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Centrosome, Cytosol" "HPA067852: , HPA068772: AB_2686031, HPA071248: AB_2686372" "unprognostic (1.88e-2)" "unprognostic (1.01e-1)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (2.44e-2)" "prognostic unfavorable (5.15e-4)" "unprognostic (9.81e-2)" "unprognostic (3.55e-1)" "unprognostic (3.78e-2)" "unprognostic (1.01e-2)" "unprognostic (2.64e-1)" "unprognostic (1.16e-3)" "unprognostic (4.29e-2)" "unprognostic (1.65e-1)" "unprognostic (6.25e-2)" "unprognostic (1.25e-2)" 18.4 15.2 9.0 8.9 9.7 6.0 17.3 8.9 10.1 20.1 7.2 20.1 9.9 23.3 4.4 12.6 18.5 9.4 13.4 9.1 9.1 15.8 12.0 16.0 7.3 10.3 9.5 19.5 12.4 11.5 24.7 9.8 10.8 16.2 6.4 3.4 13.0 8.6 14.7 13.6 15.9 11.3 8.1 18.3 13.9 8.2 8.9 6.5 18.8 8.0 5.7 18.1 15.8 9.3 10.3 8.4 12.2 15.0 27.6 18.9 9.6 20.8 14.6 11.6 15.8 4.9 4.2 11.0 7.6 23.4 10.7 13.7 9.3 17.1 4.7 20.5 21.0 11.8 11.8 7.4 14.6 6.4 14.9 17.5 8.5 14.7 10.6 18.4 22.9 10.0 49.8 18.5 13.4 6.3 11.5 6.0 3.8 12.6 9.1 13.4 17.8 4.4 9.2 13.9 11.9 17.9 11.3 19.5 12.4 7.4 9.1 11.7 20.6 27.0 13.3 12.3 11.5 8.0 7.4 3.2 12.2 6.2 13.5 0.0 0.5 0.0 0.7 0.7 0.4 0.4 0.3 0.8 0.4 0.1 0.4 0.3 0.0 0.3 1.0 0.3 0.1 0.5 9.0 9.7 8.9 10.1 9.1 9.1 10.3 9.5 10.8 8.1 8.9 9.3 12.4 12.8 8.6 20.5 7.9 2.2 1.8 3.7 4.0 9.5 7.5 7.6 11.7 5.7 5.2 9.2 6.2 4.1 11.9 10.7 1.9 7.0 0.9 5.5 12.7 10.1 9.1 2.5 14.2 4.9 4.0 10.9 11.2 8.4 5.7 14.7 12.1 8.5 7.7 3.3 13.2 10.0 6.1 8.8 3.5 1.6 8.7 7.1 7.2 14.0 5.0 5.6 5.2 8.0 17.6 6.1 8.9 9.8 9.2 2.3 7.0 7.6 7.3 9.8 0.0 7.0 11.6 4.5 1.5 5.9 3.7 3.6 7.7 10.1 6.7 1.4 MAB21L1 CAGR1 ENSG00000180660 "Mab-21 like 1" Q13394 13 35473789-35476689 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, Nucleotidyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 21.9;retina: 68.7" "Group enriched" "Detected in some" 14 "Bipolar cells: 57.7;Cone photoreceptor cells: 50.1;Horizontal cells: 87.5;Muller glia cells: 151.1;Rod photoreceptor cells: 125.8" "Cancer enhanced" "Detected in some" "glioma: 1.0" "Region enhanced" "Detected in many" "cerebellum: 21.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 36.6;BJ hTERT+: 29.9;BJ hTERT+ SV40 Large T+: 41.7;HBF TERT88: 44.9;hTERT-RPE1: 86.2;SH-SY5Y: 133.5" "Group enriched" "Detected in many" 10 "cerebellum: 40.9;midbrain: 18.6;pons and medulla: 12.4" "Region enhanced" "Detected in all" "cerebellum: 33.0" "HPA049324, HPA059864" Approved Nucleoplasm NA NA "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA049324: AB_2680712, HPA059864: AB_2684147" "unprognostic (4.44e-2)" "unprognostic (2.82e-2)" "unprognostic (2.79e-3)" "unprognostic (3.87e-4)" "unprognostic (5.67e-2)" "unprognostic (5.26e-2)" "unprognostic (1.71e-1)" "unprognostic (4.12e-3)" "unprognostic (1.64e-1)" "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (3.19e-2)" "unprognostic (6.93e-3)" "unprognostic (1.14e-1)" "unprognostic (3.72e-1)" "unprognostic (2.86e-1)" 2.3 4.3 1.3 0.5 1.2 0.0 7.5 21.9 2.0 0.4 0.3 2.2 0.5 0.1 0.1 0.2 0.1 0.2 0.7 1.6 0.3 0.1 0.0 0.1 0.8 2.8 6.1 0.9 0.1 0.0 0.3 0.0 3.7 1.4 0.5 68.7 2.9 0.3 5.7 2.0 1.1 0.2 3.2 0.4 0.7 0.1 2.1 0.4 1.2 0.6 0.3 0.8 0.9 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.1 36.6 29.9 41.7 23.4 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.6 0.1 44.9 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.2 0.0 0.1 86.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 3.6 133.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.3 0.0 1.5 0.0 0.0 0.0 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 21.9 2.0 1.6 0.3 2.8 6.1 3.7 3.2 2.1 0.6 2.6 0.0 0.0 0.0 0.0 0.8 0.5 0.6 0.0 57.7 0.2 0.9 0.5 0.0 0.0 0.0 50.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.9 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.0 2.5 1.2 0.7 0.0 0.1 87.5 0.2 0.0 0.0 0.0 0.4 0.0 0.3 0.4 1.8 0.0 0.0 151.1 0.0 1.5 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 125.8 0.0 5.6 3.1 0.0 0.0 0.0 0.6 0.0 0.1 0.5 0.0 0.3 MAB21L2 ENSG00000181541 "Mab-21 like 2" Q9Y586 4 150582151-150584693 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 174.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.0;Cholangiocytes: 28.6;Horizontal cells: 25.2;Muller glia cells: 7.8" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.3;pancreatic cancer: 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTERT-RPE1: 101.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA049324, HPA059864" Enhanced Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA049324: AB_2680712, HPA059864: AB_2684147" "unprognostic (1.12e-1)" "unprognostic (3.67e-2)" "unprognostic (4.03e-2)" "unprognostic (2.63e-1)" "unprognostic (2.32e-1)" "unprognostic (3.85e-2)" "unprognostic (8.99e-2)" "unprognostic (2.76e-2)" "unprognostic (2.75e-1)" "unprognostic (6.60e-2)" "unprognostic (4.78e-3)" "unprognostic (1.18e-1)" "unprognostic (6.81e-2)" "unprognostic (1.68e-1)" 0.9 4.1 0.7 8.7 0.7 0.0 0.1 1.0 1.0 0.0 7.5 174.2 9.0 0.1 1.3 1.4 0.1 1.0 1.1 0.5 1.8 0.0 0.9 0.0 0.0 16.8 10.4 0.0 0.1 0.0 0.2 0.0 17.0 0.1 10.2 7.4 5.8 0.3 0.2 0.2 38.7 20.3 5.7 0.0 0.5 0.0 2.0 0.7 3.3 0.0 0.0 0.1 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.5 0.0 0.0 0.0 101.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 1.0 1.0 0.5 1.8 16.8 10.4 17.0 5.7 2.0 3.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.0 0.0 0.0 1.4 28.6 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 25.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 MACF1 "ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF" ENSG00000127603 "Microtubule actin crosslinking factor 1" Q9UPN3 1 39081316-39487177 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" Actin-binding "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1079.0;Cone photoreceptor cells: 779.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013713, HPA068064, HPA068103" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 25000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions, Actin filaments" "HPA013713: AB_10600821, HPA068064: AB_2685946, HPA068103: AB_2685953" "unprognostic (2.71e-1)" "unprognostic (3.14e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (9.00e-2)" "unprognostic (6.19e-3)" "unprognostic (1.32e-1)" "unprognostic (7.40e-3)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" "unprognostic (3.98e-1)" "prognostic favorable (2.77e-5)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (8.57e-2)" "unprognostic (4.22e-2)" 69.1 62.5 172.0 27.7 197.5 36.2 54.6 174.6 181.6 65.9 119.1 148.6 18.6 130.3 48.7 46.4 92.0 46.4 127.0 159.7 166.1 85.7 63.8 183.6 35.9 190.2 179.0 92.6 51.2 96.9 69.3 34.6 182.9 68.2 25.1 121.2 57.7 41.6 73.0 121.0 62.6 54.2 155.6 84.9 71.3 50.2 193.2 39.3 73.3 55.2 22.8 80.3 62.7 185.3 48.1 54.9 66.7 29.3 53.8 47.3 29.8 62.2 79.4 38.0 33.7 34.3 56.5 24.4 64.6 84.0 62.1 30.6 12.5 45.7 51.2 43.5 33.1 34.0 43.4 56.5 66.0 30.8 15.9 37.0 46.5 105.1 54.3 83.5 104.7 52.0 63.2 25.7 137.0 16.0 23.3 52.7 95.8 20.0 31.7 38.5 89.6 4.5 206.0 50.8 38.2 38.6 24.9 17.2 62.5 76.3 7.5 37.9 115.1 61.6 48.5 28.8 101.9 19.4 19.7 28.8 101.0 32.6 55.2 7.5 1.3 3.8 12.2 2.7 5.9 2.2 5.8 7.8 1.8 3.8 4.7 6.1 1.3 6.5 2.9 2.5 3.0 2.0 172.0 197.5 174.6 181.6 159.7 166.1 190.2 179.0 182.9 155.6 193.2 185.3 135.3 150.6 128.2 1079.0 68.7 154.4 74.9 43.0 60.3 387.7 52.5 50.9 246.1 61.5 70.7 80.9 779.8 52.6 120.5 35.4 0.0 113.3 9.6 140.6 124.4 164.3 36.1 57.6 320.6 114.6 62.1 108.2 65.2 180.1 77.7 194.3 132.1 47.9 52.1 117.8 367.5 27.2 22.4 59.7 46.3 11.8 43.8 74.8 71.2 342.9 59.0 107.8 158.6 494.6 410.7 193.5 17.7 112.5 81.0 89.7 22.5 20.6 71.3 398.5 105.2 95.5 136.7 62.6 33.7 43.5 191.5 69.9 131.2 76.5 19.7 78.8 MAGEL2 "NDNL1, nM15" ENSG00000254585 "MAGE family member L2" Q9UJ55 15 23643549-23647867 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" Repressor "Autism spectrum disorder, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 23.2;pituitary gland: 8.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.7;Granulosa cells: 5.0;Horizontal cells: 3.3;Inhibitory neurons: 5.8;Leydig cells: 2.8;Muller glia cells: 2.2;Spermatocytes: 2.7" "Cancer enriched" "Detected in some" 4 "testis cancer: 4.3" "Region enhanced" "Detected in many" "hypothalamus: 23.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.2;JURKAT: 1.2;NTERA-2: 1.9;SuSa: 2.2" "Region enhanced" "Detected in many" "hypothalamus: 17.7" "Low region specificity" "Detected in all" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (3.18e-1)" "unprognostic (2.63e-1)" "unprognostic (2.21e-1)" "unprognostic (7.47e-3)" "unprognostic (1.65e-2)" "unprognostic (3.80e-1)" "unprognostic (1.17e-1)" "unprognostic (5.38e-3)" "unprognostic (3.51e-3)" "unprognostic (8.61e-2)" "unprognostic (1.31e-2)" "unprognostic (9.55e-2)" "unprognostic (2.96e-9)" "unprognostic (1.66e-4)" "unprognostic (3.30e-2)" "unprognostic (2.06e-4)" "unprognostic (1.79e-2)" 0.4 0.2 4.6 0.1 3.2 0.0 0.3 0.1 3.9 2.4 0.0 0.2 0.0 1.5 0.2 0.0 0.5 0.2 0.1 0.9 23.2 0.1 0.0 0.0 0.0 3.8 2.6 2.1 0.8 0.0 8.7 1.3 5.4 0.2 0.0 0.7 0.1 0.4 0.0 0.1 0.1 0.6 2.3 0.3 0.1 1.5 10.6 0.0 0.7 0.1 0.0 0.1 0.9 0.9 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.4 0.0 0.2 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 3.2 0.1 3.9 0.9 23.2 3.8 2.6 5.4 2.3 10.6 0.9 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.8 0.2 0.0 0.0 2.7 0.0 0.0 0.9 0.0 0.0 0.0 5.0 1.1 0.0 0.0 3.3 5.8 0.0 0.0 0.0 0.0 0.5 2.8 0.0 0.0 1.9 0.0 2.2 0.0 2.0 0.4 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.7 2.7 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 MAMLD1 "CG1, CXorf6, F18" ENSG00000013619 "Mastermind like domain containing 1" Q13495 X 150361422-150514178 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 33.0;Excitatory neurons: 27.5;Leydig cells: 33.8;Oligodendrocyte precursor cells: 81.4;Peritubular cells: 24.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 23.3;U-2197: 36.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003923 Uncertain Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA003923: AB_10602034" "unprognostic (4.18e-3)" "unprognostic (1.74e-1)" "unprognostic (1.63e-1)" "unprognostic (4.29e-2)" "unprognostic (4.16e-2)" "unprognostic (5.09e-2)" "unprognostic (2.31e-1)" "unprognostic (7.68e-2)" "unprognostic (2.08e-2)" "unprognostic (9.74e-2)" "unprognostic (9.86e-3)" "unprognostic (4.82e-2)" "unprognostic (1.86e-1)" "unprognostic (3.33e-2)" "unprognostic (3.58e-2)" "unprognostic (1.41e-3)" "unprognostic (9.76e-3)" 4.7 2.6 4.9 1.4 5.6 1.6 3.4 0.1 4.6 4.2 0.0 3.1 0.9 5.3 2.2 1.7 5.0 2.4 2.0 4.3 9.3 1.9 1.7 4.8 1.6 1.8 1.3 12.9 3.1 2.0 4.3 1.7 4.4 3.1 1.1 2.9 1.8 6.6 4.5 1.8 1.3 3.1 1.0 1.4 1.9 10.3 11.1 0.8 1.1 1.9 1.0 3.7 2.3 0.1 7.3 2.9 3.8 7.6 10.9 4.1 0.0 6.8 14.3 10.3 23.3 0.0 0.4 0.0 3.4 16.3 8.1 0.2 4.2 3.2 14.0 10.4 0.3 0.1 8.8 0.2 8.1 0.4 0.0 5.6 0.6 11.7 1.4 5.2 2.2 0.6 0.2 0.0 9.9 1.4 0.0 0.1 0.7 0.0 5.4 0.5 14.7 0.4 1.7 0.1 0.9 0.8 2.4 0.2 3.8 0.9 0.2 0.1 2.8 5.5 6.9 36.8 12.2 0.4 0.5 0.2 15.2 2.9 7.6 0.0 0.0 0.0 0.2 0.0 0.3 0.6 0.4 0.3 0.0 0.2 0.3 0.7 0.1 0.1 0.0 0.0 0.5 0.2 4.9 5.6 0.1 4.6 4.3 9.3 1.8 1.3 4.4 1.0 11.1 0.1 3.3 0.0 0.5 33.0 0.4 3.4 0.9 1.2 0.0 1.5 1.9 0.9 1.9 5.7 0.2 0.0 10.4 0.0 0.1 0.0 1.9 3.2 1.1 1.4 5.2 5.5 3.6 3.2 27.5 2.5 0.0 4.8 0.0 3.3 0.0 5.4 4.6 4.8 0.5 13.5 18.3 0.6 0.0 0.8 20.5 4.6 33.8 2.3 3.6 11.2 0.6 2.2 0.0 81.4 5.0 2.2 0.1 24.0 0.3 3.1 0.0 0.4 0.1 0.6 6.6 2.8 3.4 0.3 0.4 0.2 4.1 0.0 1.9 8.3 0.0 0.4 MAP11 "C7orf43, FLJ10925, TRAPPC14" ENSG00000146826 "Microtubule associated protein 11" Q8WVR3 7 100154420-100158723 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 7.0;Extravillous trophoblasts: 7.2;Hofbauer cells: 7.7;Syncytiotrophoblasts: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019359, HPA029463, HPA029464" Approved Enhanced "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "Plasma membrane, Centriolar satellite" "HPA019359: AB_1848677, HPA029463: AB_10600001, HPA029464: AB_10600205" "unprognostic (1.57e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-3)" "unprognostic (2.59e-1)" "unprognostic (5.23e-2)" "unprognostic (1.06e-1)" "unprognostic (9.36e-3)" "unprognostic (5.68e-3)" "unprognostic (6.97e-3)" "unprognostic (1.25e-1)" "prognostic favorable (6.19e-5)" "unprognostic (2.42e-2)" "unprognostic (1.85e-2)" "unprognostic (4.26e-2)" "unprognostic (2.81e-1)" "unprognostic (3.26e-1)" "unprognostic (6.54e-3)" 7.5 13.3 9.4 16.7 9.6 11.9 8.4 9.6 10.7 9.7 7.4 20.0 14.2 11.8 6.4 15.9 9.5 7.1 7.3 10.4 12.1 16.6 17.2 10.7 20.7 11.5 11.4 6.7 13.8 17.6 17.9 7.3 12.3 12.8 11.5 4.9 15.3 8.4 5.6 25.0 22.5 5.7 7.0 32.2 17.8 30.3 12.0 13.9 15.5 3.8 12.4 9.4 10.9 9.4 7.6 9.7 11.1 18.8 6.8 3.7 12.5 13.9 10.8 9.4 6.8 7.6 8.8 9.6 12.4 10.5 14.6 14.4 5.3 11.0 3.6 18.1 10.6 7.3 13.5 6.7 8.1 9.0 32.1 7.5 7.4 9.1 7.0 6.8 8.3 9.7 15.9 16.9 12.4 23.6 20.7 19.3 12.4 14.0 13.9 12.3 5.1 10.7 8.2 8.6 14.0 14.8 12.5 35.7 7.6 7.3 7.2 10.7 11.5 18.6 15.7 24.7 10.9 24.8 25.4 9.7 10.5 12.3 20.2 0.6 0.3 1.4 0.6 0.6 0.5 0.2 0.8 0.6 0.2 0.6 0.4 0.7 1.9 0.2 0.6 0.2 0.0 0.2 9.4 9.6 9.6 10.7 10.4 12.1 11.5 11.4 12.3 7.0 12.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 7.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386837-66491544 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.5;Langerhans cells: 265.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 57.9 31.0 47.6 38.3 79.7 63.7 32.5 30.2 61.3 31.1 22.5 26.5 19.4 26.3 29.6 51.8 23.7 27.0 40.7 69.4 44.3 31.2 105.3 34.7 49.5 31.6 32.6 25.7 22.4 38.5 26.8 29.6 40.1 26.2 23.6 34.1 29.3 21.8 85.5 23.7 27.0 31.9 35.7 32.6 24.1 15.2 42.8 33.8 22.8 51.3 55.4 31.2 33.7 49.9 105.8 55.3 94.4 39.0 55.3 41.3 53.8 83.6 61.6 76.6 68.1 79.0 82.1 96.8 93.2 59.9 58.2 93.3 88.8 106.4 89.8 79.1 56.8 30.9 50.4 40.7 45.1 41.0 45.3 32.3 64.0 55.9 81.6 81.5 60.7 48.0 54.3 116.7 113.4 40.3 33.5 51.9 47.9 93.9 42.9 39.2 58.1 84.7 74.8 48.5 58.3 31.7 60.8 45.5 63.0 74.9 41.0 33.7 90.8 99.5 63.8 71.1 112.4 74.0 143.1 60.6 105.1 69.9 48.4 3.0 7.5 5.4 6.4 7.7 5.8 2.8 5.6 6.1 7.7 4.6 6.9 4.2 3.5 8.3 7.7 15.1 4.6 2.8 47.6 79.7 30.2 61.3 69.4 44.3 31.6 32.6 40.1 35.7 42.8 49.9 24.5 28.9 24.8 24.2 40.0 82.8 45.9 32.3 21.1 10.0 22.2 10.2 21.5 40.0 24.9 25.8 14.6 48.1 45.0 25.1 46.9 69.4 12.1 16.3 13.9 34.6 21.7 19.0 69.7 23.1 48.8 30.3 17.9 35.4 8.9 19.8 18.9 172.5 51.4 10.1 46.4 15.4 20.3 90.7 265.3 23.6 22.4 115.1 53.4 48.7 87.9 34.9 35.0 28.1 31.7 103.9 23.5 21.8 49.1 87.7 22.2 35.9 17.7 7.8 6.6 16.3 52.4 35.6 42.7 30.3 67.3 51.7 54.0 5.9 19.1 65.4 MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124122 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 724.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003835, HPA051993" Supported Supported Cytosol NA NA 140000 "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB003835: AB_562312, HPA051993: AB_2681685" "unprognostic (4.39e-1)" "prognostic favorable (3.72e-4)" "unprognostic (4.24e-1)" "unprognostic (1.26e-3)" "unprognostic (2.58e-1)" "prognostic favorable (7.98e-4)" "unprognostic (2.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (7.45e-3)" "unprognostic (4.95e-2)" "unprognostic (1.32e-1)" "prognostic favorable (5.43e-5)" "unprognostic (2.91e-2)" "unprognostic (2.25e-1)" "unprognostic (4.90e-2)" 73.9 118.4 145.5 54.1 143.1 102.4 69.1 151.5 190.7 76.6 150.4 103.4 134.0 72.3 23.2 121.6 64.7 30.4 156.6 145.9 147.3 82.6 123.3 66.8 57.1 149.6 152.9 84.1 134.3 54.9 99.3 36.4 154.3 93.9 42.7 68.0 79.6 37.6 289.0 95.8 101.0 31.7 143.5 89.1 92.7 131.6 150.7 69.3 74.6 132.1 41.0 77.2 75.2 142.8 163.1 175.4 93.7 132.8 127.1 151.9 93.8 104.5 138.8 139.6 125.8 153.0 85.5 137.7 95.9 120.0 111.9 114.3 74.2 111.6 107.4 118.1 90.4 50.5 91.4 171.7 194.0 93.6 101.8 168.8 106.8 98.2 129.5 185.5 125.2 123.0 98.1 263.1 119.3 203.5 186.3 130.6 107.8 118.6 125.9 140.7 61.9 159.1 123.5 102.7 126.8 126.3 95.7 130.6 344.1 107.3 101.0 158.5 111.8 113.6 98.2 293.4 163.9 263.1 172.4 100.2 176.5 166.8 199.3 27.5 13.0 45.4 16.9 16.6 13.6 13.0 13.3 17.2 15.9 18.2 12.3 15.9 21.2 18.8 14.1 9.0 14.3 7.3 145.5 143.1 151.5 190.7 145.9 147.3 149.6 152.9 154.3 143.5 150.7 142.8 77.7 9.6 31.9 22.5 62.3 35.4 93.3 21.3 15.4 85.1 92.9 95.4 62.9 44.3 22.8 40.5 41.7 28.7 102.3 300.5 146.8 20.7 248.1 59.5 68.3 52.1 63.2 123.1 17.6 45.5 38.6 60.3 64.7 48.8 19.7 124.4 49.2 48.1 55.0 121.1 23.2 107.7 16.2 56.0 38.2 724.3 35.8 65.6 42.7 10.3 28.5 121.1 62.8 13.0 24.2 47.0 151.8 23.0 79.9 103.2 166.1 92.8 18.9 106.8 26.3 93.1 71.8 23.5 17.4 42.9 63.9 35.6 77.0 120.2 119.9 113.1 MAP3K20 "MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK" ENSG00000091436 "Mitogen-activated protein kinase kinase kinase 20" Q9NYL2 2 173075435-173268015 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 261.9;tongue: 279.7" "Cell type enhanced" "Detected in many" "Adipocytes: 57.5;Alveolar cells type 2: 57.7;Cytotrophoblasts: 52.6;Endometrial stromal cells: 96.7;Granulosa cells: 100.7;Smooth muscle cells: 83.2;Theca cells: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 15.5" "Group enriched" "Detected in many" 5 "dendritic cells: 15.5;monocytes: 9.4" "Cell line enhanced" "Detected in many" "U-138 MG: 176.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017205 Approved Supported Cytosol NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA017205: AB_1858933" "unprognostic (2.90e-2)" "unprognostic (9.99e-3)" "unprognostic (4.63e-3)" "unprognostic (1.98e-1)" "unprognostic (7.63e-2)" "unprognostic (5.02e-2)" "unprognostic (2.34e-2)" "unprognostic (3.89e-3)" "unprognostic (2.83e-2)" "unprognostic (9.27e-2)" "unprognostic (4.54e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (3.41e-6)" "unprognostic (2.34e-1)" "unprognostic (1.86e-1)" "unprognostic (2.23e-1)" "unprognostic (1.19e-2)" 71.0 11.4 9.5 20.5 9.7 4.7 21.4 10.3 8.5 44.9 15.7 65.8 13.0 76.4 18.6 50.0 48.0 31.4 195.7 9.3 12.1 7.5 25.2 22.5 9.8 13.8 14.7 69.5 11.7 49.3 3.8 27.6 11.2 44.0 20.9 2.5 12.4 57.1 261.9 14.1 19.2 75.0 11.1 12.5 31.5 10.6 12.5 11.5 16.4 279.7 10.2 56.1 21.2 9.4 34.6 28.6 22.0 29.1 62.7 92.5 13.8 121.9 94.7 55.9 59.6 19.5 22.2 26.5 31.2 122.5 48.8 22.9 33.1 64.6 124.2 52.0 22.0 43.3 30.5 4.1 24.8 39.3 43.8 74.7 27.2 105.2 164.2 46.3 37.5 28.5 19.8 4.9 36.8 14.8 24.8 19.0 12.2 28.9 16.0 36.2 45.0 0.1 13.6 19.6 12.9 12.4 47.0 11.3 19.7 35.6 12.9 20.9 37.9 176.3 71.4 53.1 27.9 0.1 0.1 5.5 126.2 10.6 18.9 0.2 9.4 0.0 1.0 8.3 1.0 1.6 0.8 1.7 15.5 2.5 0.0 0.8 2.6 0.5 8.2 0.3 0.8 3.4 9.5 9.7 10.3 8.5 9.3 12.1 13.8 14.7 11.2 11.1 12.5 9.4 57.5 38.5 57.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 20.0 44.4 0.0 0.0 7.4 11.0 0.0 52.6 2.3 0.0 1.9 43.9 0.0 36.7 96.7 14.1 0.0 0.0 0.0 27.6 21.9 36.5 0.0 35.6 5.1 100.7 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 15.5 0.0 0.0 0.0 0.0 38.6 0.0 0.0 1.4 0.0 0.0 1.9 13.1 0.0 0.0 0.0 83.2 0.0 0.0 0.0 0.0 21.6 3.6 70.5 0.0 0.0 MAP3K7 "MEKK7, TAK1" ENSG00000135341 "Mitogen-activated protein kinase kinase kinase 7" O43318 6 90513573-90587072 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007633, HPA075335" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Nuclear speckles, Plasma membrane" "HPA007633: AB_1079359, HPA075335: " "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (1.35e-1)" "unprognostic (6.48e-2)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (9.77e-2)" "unprognostic (6.51e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (2.56e-3)" "unprognostic (4.76e-2)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "unprognostic (1.17e-1)" 11.8 12.5 13.1 12.5 15.1 8.7 14.3 15.6 17.3 14.3 11.7 11.6 9.2 16.6 16.5 10.6 11.0 12.7 16.9 14.7 14.9 11.4 11.6 10.4 16.4 15.3 13.7 15.8 9.7 16.3 13.0 17.4 15.8 14.9 10.9 23.5 12.1 13.3 16.9 13.9 9.8 14.0 15.3 17.6 10.8 9.9 13.8 20.8 14.7 18.4 16.8 14.3 12.2 22.4 16.7 14.4 41.3 35.6 29.5 39.1 29.0 32.7 37.7 28.8 36.1 18.6 15.5 36.9 20.4 35.6 25.6 17.3 26.3 25.5 48.7 19.0 27.7 32.9 19.9 24.9 30.8 36.9 24.4 32.5 30.5 28.2 34.2 33.1 27.4 31.8 67.0 29.3 41.8 20.3 17.2 31.2 34.0 25.7 18.0 29.3 73.9 18.0 24.2 18.4 20.8 29.5 22.9 15.6 24.8 32.2 15.5 64.7 26.5 23.3 14.7 21.6 30.9 25.9 24.7 15.8 35.7 39.7 35.0 18.2 11.5 18.4 12.8 15.9 14.5 13.0 12.3 12.5 14.6 9.9 13.7 13.4 11.5 17.9 17.6 8.9 20.8 13.4 13.1 15.1 15.6 17.3 14.7 14.9 15.3 13.7 15.8 15.3 13.8 22.4 16.1 16.0 26.9 47.0 24.3 36.3 20.8 19.5 21.6 23.3 17.9 12.3 31.0 14.3 16.9 16.5 27.1 31.8 17.8 12.4 7.9 17.6 3.6 10.9 19.8 21.2 12.1 14.1 85.7 20.9 34.6 23.2 16.3 14.8 13.9 25.9 25.7 20.7 24.3 28.6 63.8 13.7 20.3 27.3 24.6 3.2 26.8 21.7 21.4 36.5 35.2 19.6 16.5 50.8 137.2 20.1 9.1 41.0 18.8 30.1 11.1 16.6 21.4 21.5 19.7 28.0 18.5 25.9 24.9 21.3 37.2 48.4 22.7 18.1 15.1 24.8 MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21759657-21867680 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 341.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069, CAB079930, CAB079932, CAB079933" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nuclear speckles" "CAB004229: AB_627547, CAB079930: , CAB079932: , CAB079933: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (9.41e-3)" "unprognostic (2.68e-1)" "unprognostic (2.50e-3)" "unprognostic (4.17e-1)" "unprognostic (4.44e-3)" "unprognostic (1.72e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (6.49e-2)" 31.1 33.1 64.8 35.9 84.4 41.2 29.8 37.3 80.9 31.4 32.9 36.1 25.8 29.6 30.1 43.0 29.0 28.9 42.2 91.3 46.4 42.1 34.2 38.5 36.8 29.1 45.1 29.2 38.1 51.7 12.0 33.1 35.9 32.8 36.2 30.3 28.9 32.7 38.1 45.0 29.5 39.1 43.8 40.5 33.9 43.7 60.1 44.4 46.1 41.9 41.9 35.5 18.9 43.2 78.7 48.0 60.5 37.2 75.9 76.7 25.9 84.7 77.5 73.2 72.0 43.8 40.8 45.8 41.3 112.7 67.5 74.6 73.9 67.9 97.8 180.4 72.1 78.9 43.0 67.7 73.5 113.2 80.5 56.9 60.1 89.4 81.6 58.0 101.7 45.4 341.9 50.5 97.5 36.6 72.0 38.5 24.4 104.5 46.8 79.4 149.6 13.2 55.5 62.9 50.0 28.6 91.5 64.2 57.2 60.4 42.4 47.1 90.1 61.5 79.6 71.9 54.2 47.1 59.4 65.8 60.0 60.0 68.4 1.4 4.9 7.2 15.9 6.0 4.9 2.3 3.6 6.0 4.1 2.6 3.5 6.1 16.5 9.3 6.9 4.0 3.4 4.0 64.8 84.4 37.3 80.9 91.3 46.4 29.1 45.1 35.9 43.8 60.1 43.2 36.8 48.1 35.8 97.6 44.0 60.2 28.4 25.1 28.5 25.5 32.5 24.5 41.5 42.9 31.2 51.5 54.2 21.8 151.7 74.4 19.6 28.5 49.0 33.5 40.3 39.9 59.6 63.8 109.2 39.2 23.2 38.4 52.0 45.0 92.8 28.8 52.1 63.5 53.2 28.6 91.2 42.2 26.4 89.0 77.1 14.7 32.6 74.9 40.9 68.4 75.0 35.8 143.2 82.4 75.1 45.3 35.2 44.4 37.0 43.8 32.8 46.0 32.2 22.4 32.9 44.6 37.3 74.1 53.4 44.9 61.8 19.2 91.4 43.3 38.6 38.8 MAPK8IP3 "JIP3, JSAP1, KIAA1066, syd" ENSG00000138834 "Mitogen-activated protein kinase 8 interacting protein 3" Q9UPT6 16 1706183-1770351 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 62.1;Horizontal cells: 87.5;Inhibitory neurons: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005580, HPA041785, HPA069311" Approved Approved Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 57: B-cells - Immune response" Vesicles "CAB005580: AB_627840, HPA041785: AB_2677671, HPA069311: AB_2686116" "unprognostic (1.49e-1)" "unprognostic (2.22e-1)" "unprognostic (8.28e-3)" "unprognostic (8.32e-2)" "unprognostic (3.90e-1)" "unprognostic (6.83e-3)" "unprognostic (3.66e-2)" "unprognostic (2.41e-2)" "unprognostic (1.55e-1)" "unprognostic (8.67e-2)" "unprognostic (1.57e-2)" "unprognostic (6.91e-3)" "prognostic unfavorable (5.25e-5)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (2.45e-1)" "prognostic favorable (3.95e-4)" 25.1 32.2 29.3 13.5 36.5 26.4 26.1 16.2 64.9 38.6 0.0 26.9 13.5 25.9 4.0 20.2 31.7 7.9 39.3 39.7 18.5 34.1 30.8 31.7 16.3 39.5 17.4 46.8 39.3 7.0 78.6 8.5 34.9 43.6 3.8 11.3 28.8 7.4 22.1 37.0 39.4 4.4 7.9 49.8 25.9 32.0 18.4 11.8 38.3 4.3 6.5 35.2 30.5 44.9 6.5 12.2 12.7 11.4 6.1 10.3 9.9 10.7 4.0 5.2 4.6 17.3 21.0 7.5 6.6 6.7 3.7 12.1 3.1 7.0 1.7 11.9 14.1 10.0 33.6 13.4 8.4 6.5 16.9 20.7 9.2 7.6 3.7 22.9 6.9 14.1 8.6 14.1 5.5 16.6 10.2 28.5 8.5 3.2 6.9 44.1 6.3 12.9 6.4 8.4 26.4 21.0 12.8 11.8 5.3 5.8 6.4 9.1 21.9 21.8 12.2 9.4 8.6 31.4 5.8 9.7 5.7 6.7 11.1 0.0 0.2 0.5 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.1 29.3 36.5 16.2 64.9 39.7 18.5 39.5 17.4 34.9 7.9 18.4 44.9 9.1 3.2 7.8 46.7 30.5 9.8 4.3 10.0 13.1 40.8 7.9 7.5 6.6 10.0 10.5 3.7 37.5 5.6 10.4 16.8 1.9 4.9 24.9 13.2 13.0 7.8 10.2 8.6 62.1 3.8 5.7 7.5 34.7 21.9 1.3 23.4 6.4 9.7 7.2 87.5 65.2 11.1 10.2 10.3 12.5 23.4 7.8 13.5 7.2 31.9 8.7 11.9 9.2 32.6 52.8 7.7 9.5 9.1 17.6 4.7 10.3 1.2 15.9 19.2 6.6 7.3 8.2 19.8 5.1 10.8 9.7 5.6 11.8 5.9 11.7 6.0 MAPKBP1 "KIAA0596, NPHP20" ENSG00000137802 "Mitogen-activated protein kinase binding protein 1" O60336 15 41774434-41827855 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 204.3;Excitatory neurons: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030832, HPA030833" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 46: Basophils - DNA binding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA030832: AB_10601869, HPA030833: AB_2673628" "unprognostic (2.53e-1)" "unprognostic (9.18e-2)" "unprognostic (6.56e-2)" "prognostic favorable (1.47e-4)" "unprognostic (1.16e-1)" "unprognostic (2.22e-1)" "unprognostic (9.84e-3)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (6.80e-4)" "unprognostic (1.08e-3)" "unprognostic (6.03e-3)" "unprognostic (7.94e-2)" "unprognostic (1.68e-1)" "unprognostic (8.98e-2)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" 6.2 10.5 10.9 4.6 12.4 4.4 7.7 31.1 13.7 11.1 10.1 10.2 9.6 9.9 4.5 18.6 10.4 4.6 6.4 9.9 8.5 7.1 4.1 6.0 3.9 9.0 8.0 15.1 5.5 4.2 12.7 5.4 9.0 8.9 3.6 9.0 7.5 5.9 5.1 24.2 9.9 9.0 5.3 8.0 9.3 34.4 9.1 6.3 13.4 3.7 6.8 12.2 12.0 10.2 7.4 3.8 10.0 9.5 10.9 10.8 6.9 10.1 25.5 9.1 6.6 7.6 2.7 1.8 8.1 8.3 12.5 17.2 9.8 28.5 6.5 6.7 2.7 7.3 12.8 2.6 4.7 4.7 14.5 5.6 22.3 14.3 25.9 14.8 13.4 11.9 4.6 3.4 12.9 1.5 4.0 4.2 1.1 4.3 7.6 4.3 7.2 0.7 5.3 8.1 11.3 6.3 5.7 5.9 4.5 10.2 7.1 3.7 10.6 13.0 6.2 12.4 10.0 7.3 12.7 4.3 8.7 6.3 11.0 1.1 0.4 0.3 0.8 0.1 0.6 0.4 0.4 0.3 0.5 0.4 0.6 0.5 0.1 0.6 0.5 0.1 0.2 0.5 10.9 12.4 31.1 13.7 9.9 8.5 9.0 8.0 9.0 5.3 9.1 10.2 7.1 6.4 10.3 33.0 3.5 54.7 10.0 8.6 36.5 14.5 5.4 8.9 3.4 2.8 7.3 3.7 204.3 6.8 5.6 4.0 0.0 3.0 15.7 10.9 7.1 9.5 4.8 0.8 62.2 3.7 4.4 5.8 9.2 8.9 1.3 12.2 5.3 2.6 3.9 15.2 55.1 1.7 4.1 2.5 6.1 27.1 7.2 5.0 8.8 33.7 4.2 4.4 3.1 34.7 51.9 4.6 1.8 7.9 5.1 12.5 8.1 0.5 13.0 8.9 13.1 7.8 5.7 12.7 4.2 27.7 53.6 5.3 5.8 8.0 2.5 15.2 MAPRE2 "EB1, EB2, RP1" ENSG00000166974 "Microtubule associated protein RP/EB family member 2" Q15555 18 34976928-35143470 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 163.3;Oligodendrocytes: 435.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 124.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016738, HPA016739" Enhanced Uncertain Nucleoplasm NA NA 13000000 "Cluster 44: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA016738: AB_1853571, HPA016739: AB_1853570" "unprognostic (2.01e-1)" "unprognostic (3.48e-1)" "unprognostic (2.55e-2)" "unprognostic (5.30e-3)" "unprognostic (1.75e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-2)" "unprognostic (8.53e-2)" "unprognostic (1.09e-2)" "unprognostic (2.29e-1)" "unprognostic (2.93e-2)" "unprognostic (5.40e-2)" "unprognostic (2.22e-3)" "unprognostic (5.83e-2)" "unprognostic (1.34e-1)" "unprognostic (3.16e-2)" "unprognostic (3.99e-3)" 22.4 58.7 54.2 29.1 65.2 22.1 16.6 58.5 89.4 19.3 1.9 24.5 15.0 14.0 18.9 17.4 12.7 41.1 89.1 68.8 56.9 18.4 33.4 27.2 35.8 74.0 61.0 24.9 12.8 19.2 16.3 28.3 70.6 16.1 24.6 49.1 20.2 17.2 50.4 26.1 19.6 23.8 70.0 27.8 30.6 6.4 68.2 74.4 21.7 91.9 32.6 27.2 14.4 109.0 0.8 26.3 28.9 15.4 17.1 15.9 2.0 18.7 44.7 22.3 37.2 2.0 9.9 87.8 21.3 41.1 23.5 35.0 22.8 15.2 39.8 51.5 21.3 88.9 26.9 52.8 12.6 49.5 72.3 19.6 4.0 30.4 10.5 21.2 124.0 61.4 28.3 37.7 28.8 1.7 104.6 16.4 22.5 28.8 5.2 41.6 35.2 20.0 11.9 0.4 35.9 23.9 14.0 0.7 15.5 27.2 3.2 29.0 21.0 24.1 13.4 14.2 12.7 19.9 50.8 50.8 41.4 65.1 38.2 69.0 30.0 46.7 63.8 37.7 49.5 60.8 44.4 58.3 33.4 55.5 50.6 61.5 21.5 74.4 51.6 47.3 52.9 76.9 54.2 65.2 58.5 89.4 68.8 56.9 74.0 61.0 70.6 70.0 68.2 109.0 27.0 22.4 18.3 104.8 73.0 23.7 5.1 2.0 38.1 109.6 18.9 19.7 105.6 12.8 4.8 5.5 25.0 0.6 107.9 13.3 5.9 9.8 12.4 11.9 12.6 29.4 29.3 25.0 163.3 12.8 9.7 28.5 42.3 14.6 27.3 4.6 33.5 26.1 26.1 52.2 141.7 25.8 4.1 44.7 38.3 6.8 19.3 44.6 30.2 70.3 17.1 40.3 52.5 97.5 435.9 10.1 15.6 21.1 31.6 2.9 12.0 5.1 6.5 12.5 78.9 25.4 74.9 1.9 10.6 9.1 27.6 0.8 76.1 15.0 11.1 3.5 MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 120.0;heart muscle: 116.1;liver: 183.4" "Cell type enhanced" "Detected in some" "Astrocytes: 28.1;Cardiomyocytes: 38.1;Cholangiocytes: 20.0;Endometrial stromal cells: 30.6;Fibroblasts: 16.4;Hepatic stellate cells: 23.2;Hepatocytes: 65.8" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BJ: 133.3;BJ hTERT+: 498.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" No NA 8670000000 1900000000 "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favorable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" 6.3 3.6 9.4 1.3 9.4 0.0 2.8 12.9 7.0 120.0 4.9 57.5 1.9 88.4 3.3 11.1 17.7 5.1 116.1 10.4 27.0 4.8 183.4 6.0 1.0 19.2 16.5 2.7 0.2 0.3 1.0 9.0 15.3 46.0 5.6 0.0 2.3 52.2 37.5 6.3 7.5 44.4 22.2 0.8 1.6 0.5 14.6 0.2 3.2 18.9 4.3 9.9 61.5 32.0 0.0 0.0 0.3 0.4 15.7 17.3 0.1 133.3 498.3 1.8 0.9 0.0 0.0 0.1 0.0 40.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 2.6 0.0 0.0 2.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.2 0.0 0.0 5.4 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 9.4 12.9 7.0 10.4 27.0 19.2 16.5 15.3 22.2 14.6 32.0 1.1 0.0 1.8 28.1 0.2 2.9 0.1 0.2 0.0 0.0 0.0 0.0 38.1 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.9 0.7 30.6 2.0 0.0 0.0 0.2 0.0 0.3 16.4 0.0 0.7 0.0 0.2 23.2 65.8 0.4 0.0 0.9 0.0 0.0 1.9 3.7 7.5 2.5 0.3 1.8 1.0 0.0 0.0 0.0 10.1 0.2 0.0 0.0 0.7 0.1 0.1 0.0 2.4 0.0 0.0 0.0 5.4 4.5 0.0 0.0 0.2 1.7 0.1 0.5 5.1 0.0 0.1 MATN3 "EDM5, HOA" ENSG00000132031 "Matrilin 3" O15232 2 19992052-20012668 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.2;placenta: 11.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 38.5;Sertoli cells: 26.3" "Cancer enhanced" "Detected in all" "pancreatic cancer: 13.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "Hep G2: 143.4" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 1.7" HPA051250 Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" NA NA 440000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum, Golgi apparatus" "HPA051250: AB_2681406" "unprognostic (3.47e-1)" "prognostic unfavorable (1.41e-4)" "unprognostic (7.57e-2)" "unprognostic (2.75e-2)" "unprognostic (1.71e-1)" "unprognostic (1.33e-2)" "prognostic unfavorable (8.62e-5)" "unprognostic (1.27e-1)" "unprognostic (4.84e-2)" "unprognostic (7.40e-2)" "unprognostic (3.20e-2)" "unprognostic (2.54e-2)" "unprognostic (2.11e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.51e-1)" "unprognostic (7.04e-2)" "unprognostic (3.15e-2)" 2.2 0.6 5.1 0.5 3.2 0.0 2.7 3.4 5.7 2.5 2.5 0.6 0.4 2.1 0.9 0.5 1.9 2.1 0.4 3.4 3.9 1.9 0.0 13.2 0.3 5.2 6.0 0.7 0.4 0.4 0.3 11.3 5.2 1.6 0.5 0.3 0.6 4.6 0.3 0.8 0.4 1.7 4.7 0.3 1.8 0.9 7.6 0.1 1.3 0.6 0.3 0.8 1.2 3.6 6.4 4.9 16.1 0.1 4.5 9.7 1.0 2.0 1.1 6.5 8.2 4.7 2.7 0.0 0.8 1.7 6.2 1.1 0.4 12.7 9.2 0.0 0.4 0.0 1.1 143.4 1.1 0.0 0.0 21.3 0.7 7.1 1.7 4.5 8.7 0.0 0.0 0.0 13.8 2.5 0.0 0.0 5.0 0.2 2.4 0.0 0.0 0.0 19.5 4.5 0.1 2.1 10.6 1.8 6.5 27.1 19.2 0.1 4.9 9.5 11.4 0.4 1.2 0.1 0.0 0.0 1.6 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 3.2 3.4 5.7 3.4 3.9 5.2 6.0 5.2 4.7 7.6 3.6 1.6 38.5 2.2 0.0 0.0 0.3 0.3 2.6 0.0 0.0 5.4 1.3 0.3 0.0 2.3 1.8 0.0 0.1 0.1 0.0 0.0 0.4 0.4 0.3 0.8 2.8 0.0 0.0 0.1 0.2 1.9 1.9 0.0 0.5 0.0 4.4 0.0 0.0 0.1 0.0 0.2 0.0 4.1 0.0 0.3 0.4 1.5 0.1 3.6 4.7 0.0 0.0 0.0 0.5 0.2 1.1 0.0 4.5 0.0 0.3 0.0 0.8 1.6 0.0 26.3 0.8 6.8 0.0 1.3 0.0 0.1 0.1 0.1 6.3 0.0 0.2 MBTPS1 "KIAA0091, PCSK8, S1P, SKI-1" ENSG00000140943 "Membrane bound transcription factor peptidase, site 1" Q14703 16 84053761-84116942 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 318.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056109 Supported NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA056109: AB_2683040" "unprognostic (1.50e-1)" "unprognostic (9.73e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (2.50e-1)" "unprognostic (2.02e-1)" "unprognostic (1.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "prognostic favorable (2.21e-5)" "unprognostic (2.62e-1)" "unprognostic (2.92e-1)" "unprognostic (6.63e-2)" "unprognostic (6.88e-2)" 45.8 33.7 12.7 26.2 16.4 24.6 42.8 17.6 13.3 41.2 18.1 38.7 26.0 40.8 25.6 28.2 45.6 32.2 44.6 13.1 17.8 36.7 27.5 35.5 27.5 6.3 8.0 49.4 36.4 58.5 38.8 37.1 8.9 37.3 33.7 108.7 42.4 40.3 18.9 27.8 26.4 41.2 5.9 30.1 30.7 19.6 16.5 33.4 53.9 35.6 29.9 35.2 21.3 8.6 49.4 61.3 53.8 75.2 124.2 100.1 42.2 81.2 124.4 70.2 52.6 43.7 71.0 47.0 82.0 117.3 55.8 52.9 50.2 56.3 77.9 42.6 55.9 34.4 55.8 61.3 59.9 84.2 72.7 103.6 79.9 64.8 55.5 100.3 92.4 62.2 45.6 40.3 43.1 85.0 46.6 46.4 50.3 27.7 43.2 59.6 28.7 34.1 56.1 40.2 41.0 51.2 156.9 42.9 62.1 58.3 134.3 76.4 99.0 72.3 52.5 43.7 38.7 50.5 102.6 90.5 52.6 50.6 45.2 8.0 16.3 15.0 16.3 13.8 16.8 11.3 14.0 15.4 12.8 9.6 16.9 15.3 4.5 17.0 11.6 7.1 9.6 18.3 12.7 16.4 17.6 13.3 13.1 17.8 6.3 8.0 8.9 5.9 16.5 8.6 54.3 48.1 50.7 27.1 33.5 13.8 24.2 25.9 19.9 68.4 62.2 56.1 50.5 44.3 41.9 25.8 166.8 24.4 41.0 28.9 11.7 24.1 0.9 70.4 67.8 39.8 34.9 19.4 50.4 27.5 21.4 48.4 23.0 92.7 29.1 103.1 36.0 33.8 16.7 84.1 53.5 26.6 28.5 21.0 10.8 5.5 53.4 23.3 19.6 36.5 22.5 44.4 29.9 57.8 39.0 30.2 24.8 50.4 59.3 30.1 20.3 17.5 56.4 318.6 26.3 60.9 42.2 12.6 24.2 23.4 15.8 21.6 34.3 75.5 33.8 28.6 MBTPS2 "KFSD, S2P" ENSG00000012174 "Membrane bound transcription factor peptidase, site 2" O43462 X 21839617-21885423 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Metalloprotease, Protease" "Disease variant, Ichthyosis, Osteogenesis imperfecta, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005494, CAB009486" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Mitochondria, Cytosol" "CAB009486: AB_2140370, HPA005494: AB_1079329" "unprognostic (7.97e-3)" "unprognostic (9.12e-2)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (7.22e-2)" "unprognostic (3.32e-1)" "unprognostic (9.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.77e-1)" "unprognostic (8.38e-2)" "unprognostic (7.76e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (3.05e-2)" 8.6 10.6 3.5 5.2 4.0 1.7 8.8 7.8 4.9 7.5 4.5 5.1 5.2 9.7 6.0 5.8 7.3 6.7 7.7 3.7 4.1 9.4 18.7 5.5 5.0 4.4 4.1 12.5 7.3 11.0 3.8 11.6 4.9 10.5 6.0 8.8 6.6 8.5 7.1 3.7 4.2 10.1 4.1 4.8 5.8 4.1 4.2 4.9 9.0 9.1 4.7 6.8 4.0 6.1 16.9 34.5 16.1 16.5 19.8 24.4 7.7 24.4 24.7 22.7 19.7 13.8 22.5 14.6 12.4 26.2 44.4 15.4 22.4 14.0 27.9 10.9 17.8 7.2 19.7 11.4 27.1 15.6 6.8 23.2 14.8 34.3 25.1 23.0 17.8 8.4 20.3 15.8 26.1 10.5 6.4 8.1 15.0 8.8 25.1 7.9 29.8 16.4 15.7 8.4 3.9 32.8 34.3 21.5 30.5 21.3 28.9 13.2 21.2 28.4 6.6 41.9 18.5 19.1 26.0 6.9 31.6 6.4 28.0 0.0 2.2 0.8 2.2 2.5 2.0 1.9 1.6 2.0 3.6 1.7 2.2 2.6 0.2 2.6 2.6 2.4 3.2 1.7 3.5 4.0 7.8 4.9 3.7 4.1 4.4 4.1 4.9 4.1 4.2 6.1 5.5 9.6 11.5 16.6 5.8 5.5 4.8 7.0 8.0 11.8 7.5 5.1 13.3 8.6 7.1 7.3 18.8 7.0 2.2 3.8 0.0 5.9 0.3 4.0 11.5 5.6 2.4 2.1 16.8 8.9 7.1 10.8 6.1 3.7 10.8 14.5 7.5 18.7 9.4 30.3 25.0 3.4 12.2 9.2 4.0 1.9 10.5 4.8 10.6 11.2 5.0 7.3 3.1 21.6 22.2 6.1 2.4 13.2 9.1 7.4 4.9 7.2 10.7 14.5 0.0 8.6 8.3 2.7 1.5 6.5 2.7 4.8 5.1 12.3 4.3 4.9 MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400134-35425431 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 138.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.8;Erythroid cells: 96.6;monocytes: 137.7;Syncytiotrophoblasts: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Yes Yes 44000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000101: AB_2235163, HPA000845: AB_1079338, HPA052880: AB_2681979" "unprognostic (6.71e-2)" "prognostic favorable (2.81e-6)" "unprognostic (5.29e-3)" "unprognostic (7.94e-2)" "unprognostic (1.83e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.78e-4)" "prognostic unfavorable (3.95e-4)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (8.07e-2)" "prognostic unfavorable (3.58e-5)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-3)" "unprognostic (1.53e-1)" 15.2 7.1 5.8 49.1 10.4 138.7 14.4 8.3 7.4 14.5 5.8 20.2 19.6 16.3 3.3 25.1 13.7 9.6 8.9 5.8 7.0 9.1 14.9 14.8 70.1 10.3 7.7 25.6 12.6 10.3 5.3 25.2 9.6 10.2 16.7 2.3 13.9 9.6 13.3 17.6 28.3 12.2 8.1 47.3 17.9 20.6 9.0 58.9 12.1 8.0 53.6 12.7 15.6 12.3 213.0 147.5 115.7 118.8 11.0 22.2 100.6 138.1 71.2 199.4 188.3 98.9 102.4 137.9 78.8 70.5 83.6 103.8 116.0 108.3 64.4 112.7 212.6 198.3 141.5 203.7 3.9 414.0 172.4 12.3 9.7 120.0 32.4 18.4 88.7 124.5 124.0 201.2 76.9 172.7 341.8 137.9 154.9 143.4 86.7 379.6 164.8 173.0 39.4 120.1 88.2 94.8 188.3 75.4 41.8 60.9 78.8 155.6 54.1 201.3 153.1 127.2 145.4 111.9 150.2 265.2 130.9 153.5 157.6 66.5 59.8 43.4 49.5 69.6 35.8 127.5 43.1 53.1 77.8 106.1 34.0 39.0 28.4 65.5 81.2 88.8 96.6 77.1 5.8 10.4 8.3 7.4 5.8 7.0 10.3 7.7 9.6 8.1 9.0 12.3 8.1 6.4 7.3 1.3 49.5 10.6 13.6 12.1 8.6 1.5 9.2 10.8 3.5 8.6 6.0 7.3 0.0 147.8 30.4 12.0 5.9 19.8 2.8 6.2 4.1 11.8 3.5 96.6 0.3 12.7 77.1 11.2 18.8 9.0 15.2 65.7 13.2 5.3 53.1 1.7 0.4 16.6 4.1 24.0 29.4 5.1 10.8 28.4 7.2 7.5 137.7 5.7 13.4 3.0 6.0 11.0 8.6 6.0 49.3 4.0 6.5 5.7 4.8 3.7 19.7 8.8 14.5 16.1 58.8 14.9 6.3 82.2 19.4 8.5 34.6 9.8 MCPH1 "BRIT1, FLJ12847" ENSG00000147316 "Microcephalin 1" Q8NEM0 8 6406596-6648508 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 107.5;Inhibitory neurons: 94.3;Oligodendrocyte precursor cells: 78.4;Oligodendrocytes: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008238, HPA012064, CAB012177" Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear bodies" "CAB012177: AB_303207, HPA008238: AB_1853655, HPA012064: " "unprognostic (1.00e-1)" "unprognostic (2.17e-2)" "prognostic favorable (8.52e-4)" "unprognostic (6.45e-2)" "unprognostic (1.16e-2)" "unprognostic (1.19e-2)" "unprognostic (1.14e-2)" "unprognostic (1.34e-1)" "unprognostic (1.95e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "unprognostic (4.79e-2)" "unprognostic (5.55e-3)" "unprognostic (4.24e-2)" "unprognostic (2.48e-1)" "unprognostic (4.79e-2)" "unprognostic (2.94e-1)" 5.7 3.7 1.9 2.9 2.1 12.3 5.7 2.9 2.4 5.7 2.2 5.0 2.4 5.7 2.5 4.7 5.2 2.5 4.3 1.9 1.9 4.3 3.8 4.4 4.7 1.9 1.9 5.4 5.1 3.3 3.8 4.0 1.9 4.6 2.8 3.3 5.9 2.7 9.8 5.2 4.6 3.4 1.7 4.7 4.7 6.1 2.1 5.5 4.6 3.9 4.2 5.4 5.1 2.7 4.5 3.9 7.0 4.9 3.4 6.1 5.9 6.7 5.8 8.3 6.2 5.0 3.3 8.7 1.8 5.5 7.6 5.1 8.9 6.3 9.8 3.6 4.9 11.1 3.9 6.7 5.6 5.6 8.4 5.8 6.4 5.7 8.1 5.8 6.2 9.2 13.7 8.5 6.4 2.9 15.1 6.1 12.0 8.2 3.9 8.9 6.6 5.3 4.8 8.2 4.8 6.4 4.9 5.2 7.4 7.7 4.5 7.8 5.2 6.4 3.5 2.1 6.4 3.9 5.7 12.7 5.9 6.4 9.0 1.6 2.1 8.7 3.1 2.5 4.1 4.0 2.7 3.7 2.1 4.4 3.4 3.7 0.3 4.3 3.2 2.8 3.0 2.1 1.9 2.1 2.9 2.4 1.9 1.9 1.9 1.9 1.9 1.7 2.1 2.7 21.3 3.2 16.1 50.6 28.3 4.6 14.5 7.1 10.8 13.4 9.7 9.0 13.7 10.0 17.7 14.7 16.7 10.9 28.2 4.6 3.9 10.9 46.6 20.0 21.2 15.6 0.0 17.9 107.5 10.5 10.6 14.2 14.8 25.9 19.7 15.5 11.4 6.9 7.0 30.3 94.3 6.1 2.0 12.2 2.7 30.6 12.2 12.1 0.0 69.3 14.2 13.1 19.6 78.4 79.5 10.4 7.8 13.2 27.0 9.7 6.3 8.7 25.6 10.6 6.6 20.2 13.8 29.5 12.6 10.9 6.0 12.3 23.5 12.8 7.2 10.1 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MECP2 "MRX16, MRX79, RTT" ENSG00000169057 "Methyl-CpG binding protein 2" P51608 X 154021573-154137103 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 206.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 47.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 47.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000593, HPA001341, CAB037264" Enhanced Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB037264: AB_477252, HPA000593: AB_1079348, HPA001341: AB_1079347" "unprognostic (1.27e-3)" "unprognostic (2.60e-3)" "unprognostic (2.16e-3)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.35e-1)" "unprognostic (3.66e-1)" "unprognostic (6.12e-2)" "unprognostic (1.18e-2)" "unprognostic (8.81e-2)" "unprognostic (1.53e-1)" "unprognostic (1.84e-3)" "unprognostic (4.22e-1)" "prognostic favorable (7.32e-9)" "unprognostic (7.63e-2)" "unprognostic (1.00e-1)" "unprognostic (9.08e-2)" "unprognostic (6.05e-2)" 21.0 17.7 11.2 13.4 12.8 24.9 18.0 19.4 17.1 24.0 6.6 21.8 9.9 19.0 10.8 14.4 21.7 10.8 23.3 12.0 13.4 17.8 16.5 24.6 13.4 13.7 13.7 24.8 14.8 14.7 22.8 8.6 12.7 23.9 5.3 23.0 14.4 15.6 33.5 14.8 16.1 11.5 9.1 23.6 15.4 8.6 13.6 15.6 18.9 14.4 9.1 20.0 19.3 16.9 34.4 19.2 15.9 18.6 13.1 8.8 12.7 17.0 14.6 14.9 25.2 14.1 13.3 37.4 39.5 13.3 28.9 16.0 19.3 15.9 8.8 32.5 27.8 13.6 17.6 9.4 14.9 18.2 28.2 8.7 10.0 15.6 13.2 15.4 12.9 17.5 17.3 28.9 11.1 17.9 23.1 21.8 11.2 21.9 19.9 20.0 16.2 13.2 9.2 13.3 21.9 13.6 13.0 14.1 31.6 7.7 8.8 24.8 18.0 14.5 28.8 29.2 35.6 41.0 32.6 41.7 19.6 33.2 25.1 47.8 4.7 19.5 9.1 4.7 6.2 7.8 6.1 7.2 3.5 6.8 5.8 5.4 22.7 4.4 8.2 6.0 7.2 2.7 11.2 12.8 19.4 17.1 12.0 13.4 13.7 13.7 12.7 9.1 13.6 16.9 53.9 6.4 34.4 26.4 74.7 30.8 43.4 28.3 21.6 88.0 40.7 24.6 41.2 34.3 34.9 46.0 206.4 17.0 130.8 23.9 66.5 39.4 1.4 28.2 34.4 41.0 36.5 48.4 31.7 30.7 17.7 38.5 16.3 22.7 52.6 32.2 66.4 38.1 25.6 99.3 35.3 21.0 52.9 45.5 68.7 3.5 53.4 54.1 30.2 45.0 58.9 39.8 85.5 30.2 45.0 36.2 30.3 73.7 56.1 34.8 36.7 44.5 28.1 92.7 32.9 53.6 57.1 16.0 39.0 18.1 29.0 18.5 93.6 25.6 17.3 36.4 MED12 "ARC240, CAGH45, FGS1, HOPA, KIAA0192, Kto, OKS, OPA1, TNRC11, TRAP230" ENSG00000184634 "Mediator complex subunit 12" Q93074 X 71118556-71142454 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003184, HPA003185" Enhanced Approved Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA003184: AB_1079349, HPA003185: AB_1079350" "unprognostic (1.39e-1)" "unprognostic (2.23e-1)" "unprognostic (5.42e-2)" "unprognostic (2.07e-1)" "unprognostic (6.89e-3)" "unprognostic (7.14e-2)" "unprognostic (1.68e-2)" "unprognostic (1.15e-2)" "unprognostic (2.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.45e-1)" "unprognostic (2.50e-1)" "unprognostic (1.22e-3)" "unprognostic (1.28e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-1)" "unprognostic (5.16e-2)" 18.9 32.3 10.1 13.4 11.6 15.1 19.3 10.8 12.2 20.3 9.3 15.2 8.1 18.1 10.7 13.4 17.8 8.5 13.4 9.7 10.5 13.1 10.3 15.2 13.6 12.3 10.9 28.9 14.9 14.1 16.3 16.8 11.3 17.4 9.2 8.2 14.3 12.6 15.4 14.7 15.9 12.6 10.2 28.4 15.5 13.4 11.2 19.1 18.1 10.6 12.2 15.2 17.1 12.0 14.2 16.4 25.5 15.3 18.3 16.1 37.1 9.9 14.0 15.2 10.8 19.8 13.1 18.5 12.7 17.2 10.5 13.8 29.7 12.3 12.1 19.6 23.0 30.7 37.9 27.5 14.3 28.8 26.2 18.9 13.2 20.0 23.3 19.6 23.8 23.1 29.0 31.6 15.2 24.3 30.5 16.3 14.7 18.2 21.3 28.0 28.5 14.0 11.8 27.5 14.0 16.9 22.7 11.8 12.2 26.2 13.9 14.2 21.1 16.5 19.7 15.4 7.0 15.4 9.5 13.7 9.8 15.8 11.2 6.9 2.1 4.3 3.0 1.9 2.5 2.0 2.1 2.8 2.1 1.9 2.3 2.0 4.1 2.7 1.3 2.8 4.4 2.4 10.1 11.6 10.8 12.2 9.7 10.5 12.3 10.9 11.3 10.2 11.2 12.0 15.4 9.6 4.2 7.2 8.4 6.0 6.3 6.5 4.6 7.2 8.6 11.0 9.3 11.5 7.6 9.2 6.2 20.7 10.9 10.8 1.9 6.9 0.4 7.9 8.9 12.8 7.8 13.7 3.8 6.3 8.0 8.2 8.6 7.1 9.5 21.1 14.6 4.4 9.1 13.5 4.2 5.8 2.0 6.5 9.8 2.3 14.0 8.9 5.4 6.5 7.4 6.3 13.4 4.0 4.2 9.4 10.0 13.5 7.3 7.5 7.5 2.7 7.5 4.9 0.0 10.0 7.6 6.6 7.3 6.1 5.7 27.2 8.8 27.9 6.8 8.6 MED13L "KIAA1025, THRAP2, TRAP240L" ENSG00000123066 "Mediator complex subunit 13L" Q71F56 12 115957905-116277693 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 303.9;Excitatory neurons: 311.5;Inhibitory neurons: 321.0;Microglial cells: 427.2;Oligodendrocyte precursor cells: 352.8;Oligodendrocytes: 305.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "T-47d: 124.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039445 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Golgi apparatus" "HPA039445: AB_10673532" "unprognostic (1.81e-2)" "unprognostic (1.87e-2)" "unprognostic (3.32e-1)" "unprognostic (4.60e-2)" "unprognostic (5.69e-2)" "unprognostic (1.74e-2)" "unprognostic (2.55e-2)" "unprognostic (1.96e-1)" "unprognostic (1.78e-1)" "unprognostic (8.62e-3)" "unprognostic (1.54e-1)" "unprognostic (5.08e-2)" "unprognostic (1.83e-2)" "unprognostic (6.82e-2)" "unprognostic (1.54e-1)" "unprognostic (4.56e-2)" "unprognostic (4.64e-1)" 18.4 7.9 5.5 15.8 7.3 52.7 20.8 27.0 6.3 15.8 5.3 12.9 10.3 20.5 6.5 13.8 12.5 13.2 11.5 6.4 5.9 12.4 7.9 14.4 14.6 9.2 7.3 24.3 17.5 15.3 5.5 16.3 6.9 12.7 13.5 12.6 14.8 12.8 18.6 19.0 13.4 15.9 6.3 16.6 12.2 13.8 7.7 39.1 18.0 25.8 16.2 13.1 12.7 10.7 16.9 33.2 19.6 16.9 23.6 42.0 16.5 15.8 21.3 23.7 16.3 25.2 5.9 13.3 13.6 29.0 14.5 9.9 20.4 14.2 29.6 24.3 14.0 26.9 10.0 7.2 26.2 24.8 28.6 30.6 21.8 26.8 40.7 17.4 15.9 28.2 28.9 11.4 18.7 21.8 42.1 22.2 10.5 7.1 8.2 28.7 25.0 24.8 11.1 18.4 17.7 12.4 14.2 7.8 15.0 34.9 124.8 39.9 20.7 26.0 16.8 17.2 19.5 17.9 9.7 21.6 12.0 22.3 12.8 1.5 0.6 1.5 0.2 0.3 0.2 0.3 0.5 0.2 0.7 0.7 0.3 0.4 3.5 0.3 0.4 1.1 0.0 0.1 5.5 7.3 27.0 6.3 6.4 5.9 9.2 7.3 6.9 6.3 7.7 10.7 84.4 64.1 54.9 303.9 47.5 99.2 38.4 21.7 70.6 52.4 51.4 42.4 35.6 21.5 35.5 25.8 54.2 9.4 38.5 30.5 3.9 13.5 84.0 42.5 115.2 56.9 31.3 49.6 311.5 26.0 19.6 56.0 29.0 96.7 14.0 93.4 53.6 30.6 21.1 57.2 321.0 31.8 14.2 48.7 60.6 47.2 92.2 60.5 32.0 427.2 56.4 22.8 17.5 352.8 305.4 26.8 21.0 67.0 65.6 49.4 22.7 12.3 27.2 44.6 46.0 61.9 57.0 20.3 23.3 48.0 101.6 14.2 30.5 23.7 25.9 51.0 MED17 "CRSP6, CRSP77, DRIP80, SRB4, TRAP80" ENSG00000042429 "Mediator complex subunit 17" Q9NVC6 11 93784227-93814963 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebellum: 2.3;cerebral cortex: 1.3;white matter: 1.7" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046619 Approved "Nuclear speckles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA046619: " "prognostic unfavorable (4.94e-4)" "unprognostic (2.92e-1)" "unprognostic (2.72e-3)" "unprognostic (1.38e-1)" "unprognostic (6.71e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.04e-6)" "unprognostic (1.50e-1)" "unprognostic (4.48e-3)" "unprognostic (7.73e-2)" "unprognostic (1.41e-1)" "unprognostic (4.59e-2)" "unprognostic (1.02e-2)" "unprognostic (1.77e-1)" "unprognostic (2.22e-1)" "unprognostic (5.56e-3)" "unprognostic (1.48e-1)" 1.3 0.9 0.2 1.5 0.4 1.5 1.0 2.3 1.3 1.4 1.2 1.5 0.4 1.8 1.0 1.0 1.5 0.6 1.7 0.3 0.2 0.9 0.5 1.1 1.1 0.4 0.2 1.6 1.4 0.5 0.8 1.3 0.3 1.0 0.5 1.1 1.0 0.7 1.6 1.1 2.1 1.0 0.1 2.3 1.7 0.9 0.4 1.3 0.9 1.1 1.0 1.0 1.0 1.7 3.3 1.1 2.7 5.9 3.3 0.4 5.3 7.3 2.5 4.7 2.8 5.9 6.6 5.3 11.6 0.6 1.3 9.8 2.5 1.4 1.3 6.5 2.9 6.0 3.7 1.7 1.7 10.5 10.1 1.3 3.4 3.5 2.1 1.1 1.9 1.4 5.5 3.4 2.7 1.0 12.3 3.1 5.1 0.7 0.8 9.5 7.8 4.4 2.8 2.3 9.7 12.3 5.8 4.7 2.8 0.6 7.2 2.5 6.5 7.2 5.7 9.9 6.3 4.9 10.1 3.9 1.9 7.2 8.5 3.3 3.0 7.6 4.0 3.7 4.5 8.2 5.1 5.0 3.8 5.8 5.2 2.9 3.3 6.7 2.2 4.5 5.3 3.5 0.2 0.4 2.3 1.3 0.3 0.2 0.4 0.2 0.3 0.1 0.4 1.7 7.7 6.4 9.3 16.3 32.1 30.1 39.6 19.4 25.6 24.6 10.1 4.6 15.5 14.3 19.5 7.3 16.7 39.3 25.5 12.4 1.9 15.8 1.0 9.3 14.9 14.2 26.8 9.7 25.8 9.7 27.4 17.2 17.3 13.6 10.8 22.9 16.8 8.6 14.5 15.2 27.7 13.4 16.2 15.5 27.0 3.0 15.8 12.8 14.2 19.7 18.4 13.4 23.7 22.1 25.1 10.4 14.8 21.4 25.6 26.9 13.8 2.7 19.4 43.9 65.7 19.3 16.4 23.1 16.3 18.1 25.7 34.1 28.1 10.4 17.6 36.3 MED25 "ACID1, ARC92, DKFZp434K0512, TCBAP0758" ENSG00000104973 "Mediator complex subunit 25" Q71SY5 19 49818282-49840383 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Charcot-Marie-Tooth disease, Disease variant, Mental retardation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 111.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068802 Approved Supported Nucleoplasm NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA068802: AB_2686039" "unprognostic (1.72e-1)" "unprognostic (5.22e-3)" "unprognostic (6.67e-2)" "unprognostic (8.16e-2)" "unprognostic (2.20e-1)" "prognostic favorable (9.85e-4)" "unprognostic (1.02e-3)" "unprognostic (2.10e-1)" "unprognostic (3.59e-2)" "unprognostic (2.57e-1)" "unprognostic (1.72e-2)" "unprognostic (1.38e-2)" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (1.65e-1)" "unprognostic (1.39e-1)" "unprognostic (3.04e-3)" 21.6 76.1 16.2 18.5 14.4 34.5 23.7 14.7 23.4 28.6 28.4 30.5 18.6 36.2 8.7 32.3 33.3 14.8 42.5 16.3 15.5 27.7 15.8 26.4 18.3 16.3 17.5 44.9 30.6 15.8 43.7 18.9 15.8 23.8 13.2 16.0 26.9 11.9 97.8 28.7 27.9 16.0 13.2 30.5 39.3 82.1 16.6 16.9 39.8 18.4 17.8 27.3 26.4 12.9 44.6 65.3 30.5 33.3 20.8 18.4 30.7 23.6 27.4 37.3 36.6 58.7 50.1 51.2 16.3 30.9 25.6 38.4 32.8 34.0 23.1 30.9 58.3 33.7 45.6 41.2 24.6 36.0 46.1 22.7 28.3 32.8 22.9 31.4 32.3 29.0 61.6 36.3 20.8 25.5 36.0 69.8 22.5 36.9 40.6 43.5 30.3 53.3 33.6 64.1 54.4 50.1 32.4 48.9 15.2 23.3 29.1 27.1 39.3 40.1 29.2 19.4 26.6 41.3 63.1 55.3 35.6 30.8 24.4 0.8 2.2 3.8 1.3 1.7 1.5 2.3 1.1 1.4 1.8 3.3 1.2 0.8 13.8 0.9 1.6 2.2 1.4 2.0 16.2 14.4 14.7 23.4 16.3 15.5 16.3 17.5 15.8 13.2 16.6 12.9 10.6 35.3 22.9 17.0 18.5 5.6 15.8 16.0 10.2 10.8 17.7 13.3 5.7 8.6 16.8 20.2 43.8 27.5 16.1 28.8 1.9 23.6 54.3 58.3 18.3 10.8 44.3 54.7 10.5 24.3 22.8 15.8 23.0 24.1 7.6 62.5 7.1 5.8 21.5 8.4 12.6 18.8 18.3 13.8 11.6 111.7 15.8 16.5 3.6 7.5 22.8 9.1 11.3 10.6 10.9 28.7 28.6 11.3 20.4 8.8 27.8 17.6 77.4 28.3 13.1 11.9 19.8 49.1 39.0 11.3 5.3 33.8 14.5 62.0 18.0 16.5 MEGF8 "C19orf49, EGFL4, FLJ22365, SBP1" ENSG00000105429 "Multiple EGF like domains 8" Q7Z7M0 19 42325609-42378769 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 38.7;Cone photoreceptor cells: 77.2;Horizontal cells: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049248 Approved NA NA 510000000 "Cluster 11: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "HPA049248: AB_2680691" "unprognostic (5.52e-3)" "unprognostic (1.52e-1)" "unprognostic (5.35e-2)" "unprognostic (1.66e-2)" "unprognostic (1.20e-1)" "unprognostic (4.63e-2)" "unprognostic (3.25e-2)" "unprognostic (8.58e-2)" "unprognostic (9.25e-2)" "unprognostic (3.64e-2)" "prognostic favorable (6.03e-4)" "unprognostic (4.33e-2)" "prognostic favorable (2.17e-7)" "unprognostic (1.18e-1)" "unprognostic (7.34e-2)" "unprognostic (1.06e-2)" "unprognostic (1.08e-1)" 13.0 12.3 23.4 4.3 20.9 2.3 10.0 11.1 30.6 10.4 6.7 11.8 4.8 11.9 7.0 7.3 9.7 4.6 16.6 21.7 18.0 11.3 6.9 6.8 3.9 16.1 19.7 13.5 8.7 20.5 12.3 6.1 17.4 10.0 4.3 10.9 8.5 8.1 10.2 6.8 8.6 6.7 12.1 9.1 9.3 7.9 23.0 3.8 10.7 6.8 3.3 10.2 7.9 17.3 12.7 21.1 22.2 5.5 48.6 23.1 8.2 10.6 14.8 6.0 9.3 4.2 11.6 10.7 22.4 14.7 7.9 6.6 16.2 13.8 6.0 13.1 14.1 8.0 10.3 6.9 18.7 10.9 9.5 28.0 13.6 7.3 10.9 39.9 20.7 3.1 11.8 4.7 11.3 8.3 2.5 6.6 11.3 11.5 3.5 10.4 20.0 2.4 16.1 16.6 11.5 29.3 13.0 6.8 14.4 23.8 7.2 24.3 31.1 12.7 12.3 4.0 14.6 10.9 6.4 5.9 13.8 6.5 31.2 0.4 0.2 0.2 0.1 0.3 0.1 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.1 23.4 20.9 11.1 30.6 21.7 18.0 16.1 19.7 17.4 12.1 23.0 17.3 6.2 6.4 10.8 13.7 3.2 2.2 2.4 7.3 4.6 38.7 5.7 6.3 15.9 2.8 10.3 7.3 77.2 3.7 3.2 8.4 0.0 7.2 3.4 7.9 9.8 7.0 13.2 1.7 24.4 3.7 1.5 9.2 4.6 6.7 3.8 26.2 7.1 8.9 5.9 40.4 27.2 6.7 6.1 4.7 3.9 1.2 12.8 3.2 8.8 8.4 4.0 13.1 2.1 10.1 10.0 4.6 3.1 14.3 3.2 2.6 5.4 4.4 7.2 16.3 0.0 11.9 8.9 5.9 4.2 5.7 1.0 2.3 2.5 18.9 10.9 1.4 MEIS2 "HsT18361, MRG1" ENSG00000134138 "Meis homeobox 2" O14770 15 36889204-37101299 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 522.3;Cone photoreceptor cells: 254.4;Excitatory neurons: 164.7;Hepatic stellate cells: 207.4;Oligodendrocyte precursor cells: 262.4;Oligodendrocytes: 219.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "basophil: 2.9;eosinophil: 2.4" "Lineage enriched" "Detected in single" 29 "granulocytes: 2.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 114.0;SH-SY5Y: 104.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 68.4;olfactory bulb: 177.4" "HPA003256, CAB004999" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB004999: AB_425545, HPA003256: AB_1079356" "unprognostic (4.33e-2)" "unprognostic (1.94e-2)" "unprognostic (6.71e-4)" "unprognostic (2.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.24e-1)" "unprognostic (5.23e-2)" "unprognostic (1.23e-1)" "unprognostic (3.66e-1)" "unprognostic (4.73e-2)" "unprognostic (7.97e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.64e-7)" "unprognostic (6.47e-2)" "unprognostic (8.15e-2)" "unprognostic (8.79e-5)" "unprognostic (1.15e-1)" 11.1 21.9 14.4 5.3 50.4 0.0 7.4 11.7 24.9 20.9 0.6 33.2 20.6 37.0 4.1 14.2 23.3 17.8 15.7 16.0 14.7 11.1 6.9 8.4 3.4 19.2 25.7 21.1 13.4 3.5 16.4 8.6 20.0 37.7 6.4 18.8 56.8 21.6 0.7 4.4 8.3 36.3 18.0 7.6 14.1 1.6 11.8 11.1 5.4 9.5 3.4 25.6 13.5 20.3 13.3 12.0 15.3 43.6 16.7 20.6 3.6 28.3 15.6 32.9 18.4 17.2 10.8 7.6 0.7 114.0 20.8 22.4 26.9 7.2 18.1 10.9 17.3 58.8 15.8 13.9 28.6 17.5 57.2 27.3 6.3 22.3 6.6 43.2 19.1 2.8 20.1 0.1 6.4 14.3 0.1 6.7 0.2 15.8 3.9 0.0 11.1 4.1 0.0 25.7 11.9 104.0 10.8 7.1 8.0 16.5 3.4 13.3 27.3 37.6 4.6 10.1 12.1 7.5 8.1 14.6 44.3 9.7 9.6 2.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 50.4 11.7 24.9 16.0 14.7 19.2 25.7 20.0 18.0 11.8 20.3 6.5 0.0 7.3 522.3 3.4 17.5 97.3 14.1 79.1 43.8 21.0 16.3 23.9 77.2 11.4 1.8 254.4 23.3 1.0 1.0 0.0 58.4 15.2 10.5 17.1 67.2 1.8 5.3 164.7 27.1 10.0 61.7 25.5 0.8 63.3 14.9 207.4 9.6 3.4 3.3 5.0 0.4 30.5 6.5 6.1 7.4 47.8 1.1 8.8 21.5 0.6 10.7 0.0 262.4 219.7 25.7 0.3 41.3 1.8 38.3 1.4 0.1 26.5 135.9 32.9 14.7 46.4 3.6 3.1 23.8 6.1 4.5 2.3 31.2 1.0 54.1 MEOX1 MOX1 ENSG00000005102 "Mesenchyme homeobox 1" P50221 17 43640389-43661922 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.0;breast: 26.1;heart muscle: 24.9" "Group enriched" "Detected in some" 9 "Adipocytes: 63.5;Endothelial cells: 41.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 4 "T-reg: 17.5" "Lineage enriched" "Detected in single" 48 "T-cells: 17.5" "Cell line enriched" "Detected in some" 14 "HeLa: 25.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA045214, HPA063788" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA045214: AB_10959299, HPA063788: " "unprognostic (1.36e-3)" "unprognostic (2.15e-4)" "unprognostic (1.25e-1)" "unprognostic (2.58e-3)" "unprognostic (2.01e-2)" "unprognostic (5.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.55e-3)" "unprognostic (6.71e-2)" "unprognostic (2.64e-1)" "unprognostic (1.46e-1)" "unprognostic (9.36e-2)" "unprognostic (3.44e-6)" "unprognostic (2.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.82e-1)" "unprognostic (7.47e-3)" 36.0 0.5 0.0 4.7 0.0 0.0 26.1 0.0 0.1 8.0 0.0 4.7 1.6 5.5 1.1 3.7 9.0 5.7 24.9 0.0 0.0 0.2 0.1 1.4 6.6 0.0 0.0 1.0 1.5 1.2 0.5 0.1 0.0 2.6 2.4 0.0 4.9 1.9 8.3 6.6 5.1 10.6 0.0 10.8 3.0 1.1 0.0 3.0 1.9 17.1 5.3 7.7 7.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.1 0.0 0.0 1.8 0.1 0.5 0.0 0.1 0.0 0.0 0.1 0.1 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 4.3 2.7 0.0 0.0 1.7 0.5 0.0 0.3 0.0 0.0 17.5 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.5 0.0 0.0 1.0 0.3 4.1 0.0 0.0 1.2 0.0 0.4 0.6 2.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 41.3 0.0 0.0 0.7 0.0 0.3 4.8 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.0 0.0 0.0 4.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 1.0 0.0 0.1 0.3 1.8 0.1 1.5 0.3 0.0 0.0 MESD "BOCA, KIAA0081, MESDC2" ENSG00000117899 "Mesoderm development LRP chaperone" Q14696 15 80946289-80989828 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" Chaperone "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 341.4;Extravillous trophoblasts: 279.3;Syncytiotrophoblasts: 436.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039414, HPA041721" Approved Supported "Nuclear bodies,Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 1600000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "Nuclear bodies, Cytosol" "HPA039414: AB_10674981, HPA041721: AB_2756310" "unprognostic (9.21e-2)" "unprognostic (4.50e-2)" "unprognostic (8.02e-2)" "prognostic favorable (2.31e-4)" "unprognostic (4.93e-3)" "unprognostic (2.32e-3)" "unprognostic (3.47e-2)" "unprognostic (3.09e-3)" "unprognostic (4.04e-1)" "prognostic favorable (1.12e-4)" "unprognostic (7.93e-2)" "unprognostic (3.05e-2)" "unprognostic (3.42e-2)" "unprognostic (1.68e-1)" "unprognostic (4.32e-2)" "unprognostic (3.83e-1)" "unprognostic (1.88e-1)" 14.4 17.4 11.9 13.7 13.6 5.4 13.9 13.7 13.0 17.8 14.6 14.6 12.8 11.3 42.7 14.6 12.4 11.5 12.8 11.7 14.2 14.4 20.6 14.1 14.0 13.4 13.1 17.4 19.2 14.0 17.8 26.9 13.8 18.2 14.5 10.4 18.4 14.3 7.7 10.9 12.7 11.1 13.4 13.8 15.3 9.8 13.8 14.2 33.7 10.6 13.2 15.4 14.4 15.0 26.8 40.2 34.6 22.3 57.1 32.4 54.0 40.0 47.4 42.7 51.6 36.0 72.9 22.4 45.4 32.3 45.1 43.8 54.1 41.1 40.3 50.2 35.5 28.3 33.0 61.9 43.7 33.8 30.0 33.9 46.6 36.1 42.4 35.7 41.1 27.0 34.7 55.5 36.7 34.0 20.9 28.3 41.9 39.3 16.4 31.7 21.3 59.7 35.6 36.3 29.9 17.6 43.9 29.3 70.0 62.4 34.0 26.8 32.4 40.9 39.1 22.1 52.2 35.0 48.0 30.2 38.5 59.7 43.8 39.4 26.1 19.1 35.6 24.9 41.8 34.5 37.2 35.4 27.2 35.4 34.6 34.7 8.1 44.8 22.5 45.2 42.5 31.1 11.9 13.6 13.7 13.0 11.7 14.2 13.4 13.1 13.8 13.4 13.8 15.0 59.7 80.1 59.6 0.0 20.6 0.0 0.0 0.0 0.0 0.0 51.0 44.2 0.0 0.0 27.9 58.8 0.0 341.4 41.6 0.0 13.7 100.9 0.0 41.4 79.4 36.9 0.0 0.0 0.0 111.9 279.3 48.4 0.0 69.8 36.6 56.4 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.0 0.0 0.0 86.3 0.0 0.0 0.0 0.0 82.5 0.0 0.0 18.8 0.0 0.0 48.8 43.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.0 436.0 25.8 63.6 0.0 0.0 MESP2 "bHLHc6, SCDO2" ENSG00000188095 "Mesoderm posterior bHLH transcription factor 2" Q0VG99 15 89760591-89778754 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Breast glandular cells: 3.7;Exocrine glandular cells: 3.8;Rod photoreceptor cells: 7.0;Spermatogonia: 2.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.1;U-2197: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.13e-1)" "unprognostic (1.76e-2)" "unprognostic (3.75e-2)" "unprognostic (8.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.50e-3)" "unprognostic (6.59e-4)" "unprognostic (5.58e-2)" "unprognostic (4.00e-1)" "unprognostic (5.90e-2)" "unprognostic (3.14e-5)" "unprognostic (2.69e-1)" "unprognostic (1.01e-2)" "unprognostic (2.50e-1)" "unprognostic (3.81e-2)" "unprognostic (2.76e-1)" "unprognostic (1.11e-1)" 0.5 0.2 0.9 0.0 0.9 0.0 0.5 0.7 1.2 0.8 0.4 0.5 0.0 0.0 0.7 0.4 0.1 0.3 0.1 0.9 0.9 0.1 0.0 0.0 0.1 0.9 0.9 0.0 0.1 0.1 0.0 0.0 1.0 0.3 0.4 0.9 0.4 0.2 0.0 0.4 0.2 0.0 0.8 0.0 0.1 0.7 0.8 0.0 0.1 0.0 0.0 0.0 0.5 0.8 0.0 1.1 0.0 0.4 0.6 0.1 0.2 0.2 0.1 0.5 0.1 0.3 0.5 0.0 0.1 0.1 0.0 1.1 0.3 0.5 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.6 0.2 0.4 0.2 0.0 0.3 0.5 0.3 0.0 0.1 0.2 0.0 0.1 0.2 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.1 0.5 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.9 0.7 1.2 0.9 0.9 0.9 0.9 1.0 0.8 0.8 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.7 1.5 0.4 0.0 1.3 0.0 0.0 0.6 0.1 1.2 1.9 1.2 0.0 0.0 0.2 0.1 0.0 0.0 0.3 3.8 0.0 0.8 0.0 0.0 0.0 0.4 0.4 0.2 0.5 0.0 0.3 0.8 0.0 0.3 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.5 0.2 0.4 0.0 0.6 0.0 0.7 0.7 7.0 0.0 0.3 0.3 1.2 2.1 0.2 0.0 0.1 0.0 0.9 0.7 0.9 MFRP "C1QTNF5, FLJ30570, NNO2, rd6" ENSG00000235718 "Membrane frizzled-related protein" Q9BY79 11 119338942-119346705 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Microphthalmia, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "choroid plexus: 355.6" "Cell type enhanced" "Detected in single" "Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "hippocampal formation: 24.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basal ganglia: 3.5;hippocampal formation: 11.8;pons and medulla: 10.3;thalamus: 8.4" "Region enhanced" "Detected in all" "medulla oblongata: 17.6" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 49: Ciliated cells - Cilium organization" 0.0 0.0 0.7 0.0 0.3 0.0 0.0 3.5 0.9 0.0 355.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 0.2 0.0 0.0 0.0 0.0 0.6 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 3.5 0.9 24.9 0.2 0.6 1.4 0.2 0.2 3.7 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MFSD2A "FLJ14490, MFSD2" ENSG00000168389 "Major facilitator superfamily domain containing 2A" Q8NA29 1 39955112-39969968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Symport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 96.9;liver: 162.0;skin 1: 87.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 136.2;Hepatocytes: 299.6;Proximal enterocytes: 235.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 13.2;intermediate monocyte: 6.6;myeloid DC: 14.7;plasmacytoid DC: 24.3" "Group enriched" "Detected in many" 12 "dendritic cells: 24.3;monocytes: 13.2" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 52.0;THP-1: 169.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043107 Uncertain Approved "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Plasma membrane, Cytoplasmic bodies" "HPA043107: AB_10794387" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (6.92e-2)" "unprognostic (2.61e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (9.26e-2)" "unprognostic (4.11e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.33e-4)" 6.3 1.4 34.0 3.4 31.7 8.4 13.4 34.8 36.0 4.8 22.2 7.2 14.6 8.5 96.9 12.5 3.5 2.3 1.4 30.9 33.4 5.8 162.0 36.1 2.3 38.5 33.8 2.2 0.6 0.7 8.0 17.1 38.6 2.4 5.0 2.6 4.0 79.2 0.5 87.8 32.0 3.5 32.8 1.5 1.9 33.9 37.2 1.6 7.5 0.1 3.6 20.2 14.1 33.1 6.2 2.7 12.5 18.9 8.7 1.6 0.0 5.9 11.2 12.8 15.1 0.8 3.4 38.0 3.4 3.0 8.8 15.0 12.4 21.8 9.8 4.9 6.0 4.6 0.1 0.1 28.8 6.8 21.8 9.7 13.3 52.0 21.5 2.3 3.1 11.5 0.0 9.5 5.7 0.8 10.6 10.4 10.1 21.4 4.7 7.4 18.5 8.7 2.1 17.9 4.4 6.7 4.5 31.7 3.0 1.1 1.5 169.8 2.0 2.7 5.3 9.5 24.9 1.8 3.5 8.5 28.9 26.0 9.2 0.0 13.2 1.4 0.1 6.6 0.2 1.5 0.1 0.2 14.7 0.2 0.0 0.1 0.7 0.2 1.2 24.3 0.0 3.6 34.0 31.7 34.8 36.0 30.9 33.4 38.5 33.8 38.6 32.8 37.2 33.1 0.5 19.2 136.2 3.3 6.3 52.8 21.2 40.0 51.2 2.0 6.3 2.3 0.6 12.8 30.8 16.5 0.0 0.5 5.7 62.2 0.0 3.4 1.0 25.8 5.5 22.9 1.2 5.7 1.5 24.8 7.6 9.7 24.5 61.8 17.2 0.1 7.1 299.6 6.7 0.0 1.3 34.5 12.2 9.8 43.3 2.7 0.6 16.1 0.0 38.4 5.5 38.8 0.0 0.0 1.6 27.2 39.3 0.4 5.0 13.9 235.1 6.1 33.9 2.7 0.0 5.0 3.3 1.0 1.3 49.3 54.8 52.5 3.3 0.1 20.7 26.6 MGP ENSG00000111341 "Matrix Gla protein" P08493 12 14880864-14885857 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 9375.3;Breast myoepithelial cells: 4639.0;Fibroblasts: 4233.6;Hepatic stellate cells: 1826.5;Leydig cells: 2016.2" "Cancer enriched" "Detected in all" 5 "breast cancer: 845.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 9 "dendritic cells: 1.6" "Cell line enriched" "Detected in many" 5 "AN3-CA: 9874.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013949 Approved "Secreted to blood" NA NA 29000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 35: Glandular cells - Unknown function" "HPA013949: AB_1853599" "unprognostic (5.71e-3)" "unprognostic (5.85e-3)" "unprognostic (1.20e-3)" "unprognostic (2.83e-2)" "unprognostic (1.27e-1)" "unprognostic (1.21e-1)" "unprognostic (1.55e-2)" "unprognostic (4.17e-3)" "unprognostic (1.01e-2)" "unprognostic (6.93e-2)" "unprognostic (1.90e-1)" "unprognostic (4.26e-2)" "prognostic unfavorable (4.15e-6)" "unprognostic (1.55e-2)" "unprognostic (4.69e-2)" "unprognostic (7.50e-2)" "unprognostic (8.97e-3)" 1737.5 1510.2 50.6 187.4 63.8 1.6 3734.8 48.9 253.3 1738.8 198.1 1827.5 69.8 2043.8 752.9 218.2 2280.1 1083.5 2854.4 49.0 48.2 1316.9 58.1 1269.6 107.0 57.0 49.1 838.7 218.9 109.7 923.0 204.2 51.2 1955.5 277.3 7.5 2112.7 1140.7 177.0 357.6 819.0 1310.0 53.9 142.2 905.9 142.3 58.4 99.5 1500.7 275.0 65.9 987.7 1266.3 48.8 0.9 0.0 0.1 9874.6 1624.2 2.4 3.7 31.8 1.0 0.0 0.0 0.0 12.7 0.2 0.5 3.1 0.4 0.1 0.2 0.2 0.0 0.3 0.3 0.0 1.3 0.0 55.0 0.2 0.2 33.6 0.0 0.0 1.5 3.2 105.4 0.0 0.0 0.3 0.0 0.9 1.2 4.8 7.0 2.2 0.0 0.4 0.2 2.6 0.0 10.5 4.8 31.1 2.0 8.9 0.6 2.8 1810.9 0.1 21.7 11.1 1.2 3.6 28.7 0.5 0.1 1.1 9.0 0.6 8.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 50.6 63.8 48.9 253.3 49.0 48.2 57.0 49.1 51.2 53.9 58.4 48.8 451.0 19.2 72.8 1.3 29.9 149.3 220.4 0.3 19.9 0.5 9375.3 4639.0 70.2 8.6 187.5 115.8 4.2 19.0 85.7 0.1 1.9 2.3 16.9 14.7 355.8 856.1 0.0 18.7 0.2 83.4 13.5 4233.6 86.2 10.9 13.9 0.3 1826.5 6.0 30.8 0.0 0.1 0.0 0.0 9.4 219.9 67.9 2016.2 36.1 225.9 23.4 2.6 28.8 0.0 0.0 0.2 1.8 1.1 1301.8 17.0 164.3 0.0 0.7 25.8 6.8 841.5 558.8 847.0 8.2 6.1 25.8 118.5 39.5 54.5 140.6 0.0 74.6 MID1 "FXY, OS, RNF59, TRIM18" ENSG00000101871 "Midline 1" O15344 X 10445310-10833654 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 129.3;Basal squamous epithelial cells: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 156.1;AF22: 132.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002878, HPA003715" Approved Uncertain "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA002878: , HPA003715: AB_1079384" "unprognostic (1.99e-1)" "unprognostic (2.81e-1)" "unprognostic (4.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.78e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.09e-1)" "unprognostic (2.87e-1)" "unprognostic (9.43e-2)" "unprognostic (1.25e-3)" "unprognostic (9.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.12e-3)" "unprognostic (5.88e-2)" 5.9 2.5 6.9 5.0 7.7 1.7 5.3 17.2 5.0 7.0 6.5 17.3 5.7 8.9 4.9 7.0 6.4 6.8 9.3 7.0 4.9 7.3 4.2 6.5 2.2 3.6 10.4 4.4 3.5 2.8 4.2 6.2 4.9 10.4 10.6 12.3 4.9 12.9 0.7 2.9 5.8 12.3 2.1 1.0 3.8 3.6 8.2 2.3 4.2 2.2 3.1 11.7 6.2 4.4 33.2 156.1 132.5 16.7 8.1 9.2 14.6 16.2 17.8 19.7 20.7 31.0 9.7 10.6 6.5 21.9 58.4 22.5 11.0 15.1 23.0 1.3 11.0 2.7 24.3 1.1 2.8 0.3 1.2 12.1 7.0 16.1 15.8 20.4 23.1 5.1 2.1 3.2 9.6 8.0 5.3 0.5 32.7 5.1 10.0 3.9 28.9 0.4 18.7 36.2 7.1 3.5 7.4 23.5 10.1 42.7 19.2 0.2 13.7 7.2 1.0 34.1 17.0 2.8 1.2 0.4 13.5 0.3 31.3 0.5 0.1 0.6 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.1 0.7 0.0 0.1 0.4 0.0 0.1 6.9 7.7 17.2 5.0 7.0 4.9 3.6 10.4 4.9 2.1 8.2 4.4 16.5 35.3 20.7 129.3 0.7 21.4 31.5 24.7 82.6 10.7 8.5 13.2 4.8 8.6 19.6 23.9 18.8 9.1 1.3 22.6 1.9 13.4 2.2 39.8 8.9 25.4 12.1 2.7 15.5 8.7 26.9 16.2 10.7 38.5 1.3 13.4 69.9 4.0 1.5 69.0 44.3 9.0 2.0 2.5 5.8 7.9 30.1 1.2 3.6 23.4 0.0 37.0 0.0 66.4 59.2 7.3 17.2 41.3 0.2 8.2 11.3 1.5 19.3 2.9 6.6 3.7 3.3 0.3 2.4 36.1 10.1 20.0 0.8 9.7 20.0 49.2 MKKS BBS6 ENSG00000125863 "McKusick-Kaufman syndrome" Q9NPJ1 20 10401009-10434222 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" Chaperone "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041071, HPA044233" Enhanced Supported Centrosome NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Centrosome "HPA041071: AB_10960408, HPA044233: AB_10962986" "unprognostic (9.53e-2)" "unprognostic (6.70e-2)" "unprognostic (3.00e-1)" "unprognostic (3.17e-2)" "unprognostic (1.84e-1)" "unprognostic (5.65e-2)" "prognostic unfavorable (9.84e-5)" "unprognostic (5.54e-2)" "unprognostic (1.19e-1)" "unprognostic (2.58e-1)" "unprognostic (1.01e-2)" "unprognostic (1.85e-1)" "prognostic favorable (3.79e-9)" "unprognostic (3.69e-1)" "unprognostic (6.18e-2)" "unprognostic (1.63e-2)" "unprognostic (3.01e-1)" 12.0 13.3 15.3 6.7 16.6 1.9 12.3 17.9 19.2 14.3 19.6 18.9 17.3 12.6 13.7 12.7 13.1 12.7 20.6 17.0 17.2 28.8 26.0 9.9 8.4 16.4 15.2 13.8 12.4 25.5 14.8 9.6 17.0 15.0 19.4 22.8 13.0 15.4 25.4 9.3 14.5 14.3 15.4 11.8 13.9 16.2 16.3 12.2 17.6 40.6 10.7 14.4 13.3 16.0 18.9 23.3 21.7 32.9 23.3 20.9 6.7 12.7 14.4 16.6 13.3 7.7 9.6 16.2 5.3 12.4 30.0 25.0 27.6 25.1 20.6 2.9 10.4 37.1 5.8 20.9 15.8 23.4 7.5 18.5 47.5 16.0 31.7 28.0 13.5 14.8 18.8 11.7 19.7 7.1 22.3 14.2 15.6 60.8 16.4 13.2 21.5 14.5 25.7 8.6 33.0 20.9 11.9 61.3 29.7 14.5 16.8 15.5 6.3 14.6 12.4 17.8 23.3 8.6 36.3 6.9 12.1 24.3 15.3 19.5 16.0 13.4 11.7 14.2 13.8 11.3 13.0 9.9 16.8 7.8 15.1 14.1 7.9 11.9 16.9 10.8 11.0 16.4 15.3 16.6 17.9 19.2 17.0 17.2 16.4 15.2 17.0 15.4 16.3 16.0 15.0 3.2 17.9 20.5 29.8 33.9 56.5 143.1 39.9 39.1 11.5 13.7 225.7 118.7 67.0 9.2 12.5 101.6 50.3 116.4 68.4 27.0 95.4 14.7 11.5 41.2 71.2 43.5 30.2 19.8 83.4 40.1 37.8 11.5 22.8 9.1 57.5 182.4 127.1 69.0 36.1 90.0 89.5 62.5 67.5 41.7 62.4 34.5 49.8 11.2 51.1 70.7 55.6 25.6 24.7 17.6 92.9 63.9 31.5 87.4 99.6 47.4 54.7 40.1 52.6 43.9 51.5 229.1 73.6 86.4 42.8 96.9 23.5 13.0 100.7 75.5 MKS1 "BBS13, FLJ20345, MKS, POC12" ENSG00000011143 "MKS transition zone complex subunit 1" Q9NXB0 17 58205441-58219605 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021372, HPA021812" Enhanced NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA021372: AB_1848746, HPA021812: AB_2142654" "unprognostic (3.57e-1)" "unprognostic (4.12e-2)" "unprognostic (8.58e-2)" "unprognostic (3.06e-2)" "unprognostic (5.79e-2)" "unprognostic (5.05e-2)" "unprognostic (7.06e-3)" "unprognostic (6.27e-2)" "unprognostic (9.40e-2)" "unprognostic (4.64e-3)" "prognostic favorable (1.25e-4)" "unprognostic (4.33e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (9.86e-3)" "unprognostic (4.25e-1)" "unprognostic (1.05e-1)" "unprognostic (3.21e-1)" 6.6 9.9 4.2 3.6 4.7 5.8 8.3 6.9 6.1 10.6 3.6 7.8 4.5 9.6 4.3 9.0 13.9 3.9 6.9 4.2 4.3 10.4 8.7 6.2 4.6 5.2 4.9 13.4 11.4 5.7 12.2 3.6 4.8 9.1 3.2 6.1 9.2 3.4 6.7 10.8 7.7 5.0 3.5 8.2 8.5 13.3 4.4 5.8 8.9 3.1 3.9 7.8 8.4 5.7 14.2 12.0 14.5 15.9 5.2 6.4 14.7 7.0 5.9 15.6 9.5 8.4 10.2 7.3 29.5 9.0 9.2 7.7 14.8 10.1 10.8 24.5 16.5 10.2 10.6 14.1 12.5 16.0 6.4 7.0 9.4 8.7 9.3 6.6 8.7 25.5 20.1 5.4 9.2 22.5 27.8 9.7 6.4 12.3 12.0 20.8 18.5 14.6 10.8 7.9 21.4 13.7 10.7 5.9 11.9 6.7 27.8 10.5 6.5 10.6 15.7 8.1 8.8 6.9 7.6 8.6 9.7 9.2 8.3 10.4 6.3 4.2 6.0 6.2 8.7 7.3 9.6 9.3 13.1 4.1 8.9 8.4 1.9 15.7 5.1 8.3 7.8 5.9 4.2 4.7 6.9 6.1 4.2 4.3 5.2 4.9 4.8 3.5 4.4 5.7 4.0 3.2 3.1 10.1 3.3 2.5 5.1 7.9 8.6 6.4 6.6 6.9 3.6 5.7 4.6 9.2 12.5 11.5 1.8 2.9 15.6 7.4 9.5 17.7 6.1 5.1 2.4 14.9 5.8 4.0 9.6 5.6 6.1 4.4 5.7 10.9 5.0 6.3 6.0 0.0 5.3 4.9 8.2 2.5 1.8 8.3 5.3 3.1 1.8 5.6 1.7 5.5 5.2 8.0 9.2 4.8 3.1 6.8 4.3 1.5 5.0 8.2 27.4 10.5 0.0 4.9 4.6 14.0 10.7 5.5 3.3 3.1 3.8 10.2 7.8 2.1 MMP13 CLG3 ENSG00000137745 "Matrix metallopeptidase 13" P45452 11 102942995-102955732 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "urinary bladder: 12.9" "Cell type enriched" "Detected in some" 12 "Basal respiratory cells: 426.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 70.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 17.9;PC-3: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" CAB002742 Supported "Secreted to extracellular matrix" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB002742: " "unprognostic (8.98e-3)" "unprognostic (1.54e-1)" "unprognostic (4.75e-2)" "unprognostic (4.57e-2)" "unprognostic (3.05e-2)" "unprognostic (1.59e-3)" "unprognostic (1.32e-1)" "unprognostic (6.35e-3)" "unprognostic (1.69e-1)" "unprognostic (7.55e-3)" "unprognostic (2.24e-1)" "unprognostic (1.73e-8)" "unprognostic (2.12e-2)" "unprognostic (3.14e-1)" "unprognostic (4.14e-2)" "unprognostic (4.33e-2)" 0.1 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 12.9 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 17.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.0 0.0 6.7 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 2.4 1.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.7 426.0 0.0 0.0 0.0 0.0 0.2 0.0 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 6.8 0.0 0.0 0.0 2.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.8 MMP19 "MMP18, RASI-1" ENSG00000123342 "Matrix metallopeptidase 19" Q99542 12 55835433-55842966 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Angiogenesis, Collagen degradation, Differentiation" "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 58.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 54.4;Fibroblasts: 52.8;Hofbauer cells: 30.8;Kupffer cells: 35.7;Langerhans cells: 100.7;Macrophages: 61.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "thalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 75.6" "Region enriched" "Detected in many" 5 "olfactory bulb: 7.2" "Low region specificity" "Detected in all" HPA070804 Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 2100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum, Vesicles" "HPA070804: AB_2686315" "unprognostic (2.61e-1)" "unprognostic (6.56e-2)" "unprognostic (2.28e-2)" "unprognostic (2.42e-1)" "unprognostic (4.77e-3)" "unprognostic (4.77e-3)" "unprognostic (2.01e-2)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (8.56e-9)" "unprognostic (5.06e-3)" "unprognostic (1.28e-3)" "unprognostic (2.73e-2)" "unprognostic (4.00e-2)" 58.5 3.6 0.0 11.4 0.1 0.7 18.3 0.0 0.3 10.4 0.5 7.3 1.2 20.7 0.5 2.3 17.2 25.6 8.8 0.1 0.1 5.7 2.7 25.4 2.8 0.1 0.1 11.9 7.2 0.5 0.8 10.8 0.2 3.3 3.3 0.1 3.1 2.3 0.9 5.5 8.7 8.7 0.1 27.4 9.6 0.4 1.3 2.9 4.4 0.6 6.9 9.6 6.2 0.1 1.5 0.0 0.2 0.0 7.8 12.4 75.6 10.1 10.6 3.9 4.4 0.6 0.6 0.0 0.0 12.8 0.3 0.0 0.0 3.0 4.0 0.8 0.0 0.0 0.3 0.1 6.5 0.0 0.6 12.1 0.4 1.9 2.4 6.2 0.7 0.0 0.2 0.1 11.2 0.0 0.0 0.2 0.3 0.0 0.2 0.0 2.8 0.0 1.7 4.7 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.2 15.7 2.2 5.0 0.2 0.3 0.1 0.0 0.0 8.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.2 0.1 1.3 0.1 2.8 0.0 4.6 0.7 1.3 7.1 0.3 1.9 0.6 0.4 0.3 0.3 0.7 11.5 3.3 0.0 4.2 18.6 0.7 0.0 0.0 0.3 0.5 2.4 20.8 1.5 0.0 0.0 0.2 0.5 54.4 52.8 1.1 1.7 2.5 0.4 3.6 0.7 30.8 0.0 0.2 0.1 0.0 35.7 100.7 0.9 5.9 61.2 12.4 1.9 22.5 0.4 0.0 0.0 0.3 0.1 0.0 5.3 1.0 0.3 0.0 0.1 1.5 1.7 0.0 3.8 7.6 0.2 0.2 1.0 4.3 18.7 0.9 0.2 0.0 0.4 MMP21 ENSG00000154485 "Matrix metallopeptidase 21" Q8N119 10 125753580-125775821 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" Heterotaxy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "epididymis: 53.9" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Granulosa cells: 1.4;Microglial cells: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.32e-2)" "unprognostic (1.28e-1)" "unprognostic (8.51e-2)" "unprognostic (2.19e-2)" "unprognostic (4.02e-2)" "unprognostic (2.21e-2)" "unprognostic (4.22e-3)" "unprognostic (1.01e-1)" "unprognostic (2.12e-1)" "unprognostic (1.48e-1)" "unprognostic (2.89e-2)" "unprognostic (3.62e-2)" "unprognostic (9.70e-8)" "unprognostic (1.30e-2)" "unprognostic (7.69e-2)" "unprognostic (7.00e-2)" "unprognostic (2.18e-1)" 0.2 0.3 0.4 0.6 0.7 0.7 0.2 1.7 0.7 0.2 0.2 0.2 0.5 0.5 53.9 0.5 0.4 0.7 0.8 0.5 0.4 0.1 0.3 0.2 1.0 0.3 0.3 3.7 0.7 0.0 0.1 0.1 0.2 0.5 0.1 1.8 1.2 0.2 0.3 1.2 0.4 0.2 0.1 0.6 0.4 1.0 0.5 0.0 0.5 0.0 0.2 0.2 0.0 0.9 0.4 0.2 0.6 0.4 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.4 0.1 0.9 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.2 0.2 0.3 0.3 0.0 0.3 0.2 0.1 0.1 0.0 0.3 0.1 0.2 0.2 0.0 0.0 0.2 0.1 0.1 0.2 0.5 0.2 0.2 0.3 0.5 0.4 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 1.7 0.7 0.5 0.4 0.3 0.3 0.2 0.1 0.5 0.9 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 1.4 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.5 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 376.0;lymphoid tissue: 105.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 260.1;Langerhans cells: 606.0;Macrophages: 230.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.1;thalamus: 4.8" "Immune cell enriched" "Detected in some" 127 "neutrophil: 272.2" "Lineage enriched" "Detected in single" 341 "granulocytes: 272.2" "Cell line enriched" "Detected in some" 13 "NB-4: 360.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" NA NA 43300000 61000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB000348: , CAB068199: AB_2665675, CAB068200: AB_2665676, CAB068201: AB_2665677, HPA001238: AB_1079398, HPA063909: AB_2685150" "unprognostic (4.62e-2)" "unprognostic (1.64e-1)" "unprognostic (2.85e-2)" "prognostic favorable (2.55e-4)" "unprognostic (6.65e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.54e-1)" "unprognostic (8.57e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.05e-5)" "unprognostic (4.65e-1)" "unprognostic (9.85e-3)" "unprognostic (2.48e-2)" "unprognostic (2.17e-3)" 19.5 0.6 0.5 61.9 0.8 376.0 8.2 0.4 3.1 2.9 0.8 5.7 11.6 1.0 0.0 2.2 2.2 3.0 3.2 0.3 0.9 2.6 3.8 21.1 103.2 0.8 0.5 0.8 1.6 0.1 1.1 2.0 0.7 1.9 3.4 0.6 3.6 0.4 0.7 3.2 12.4 1.9 0.4 105.3 11.3 1.3 4.8 17.0 2.1 0.9 36.5 12.0 1.1 0.2 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.3 0.3 28.8 0.0 0.3 0.4 0.0 1.4 0.0 0.3 0.5 0.1 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 4.0 0.0 360.6 0.8 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.6 0.6 0.0 0.6 0.0 3.7 0.3 1.2 0.3 10.3 10.9 0.1 0.3 0.3 0.2 0.2 0.1 0.8 0.2 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 272.2 0.0 0.3 0.0 0.0 0.5 0.5 0.8 0.4 3.1 0.3 0.9 0.8 0.5 0.7 0.4 4.8 0.2 0.7 0.0 5.5 0.0 3.9 34.3 0.1 61.5 0.0 3.8 0.5 2.0 0.4 1.5 0.9 0.0 8.4 1.5 2.0 0.0 0.0 0.8 0.9 0.0 0.1 7.2 0.0 0.0 0.1 1.8 2.4 2.5 0.0 0.1 1.3 0.2 0.0 0.0 260.1 3.3 0.2 0.5 0.0 1.3 606.0 0.3 0.0 230.6 56.9 0.0 2.3 1.2 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.1 0.0 0.3 6.9 5.3 0.0 0.2 45.5 6.7 11.2 0.2 28.1 1.9 3.4 0.3 0.0 0.1 MNS1 "FLJ11222, SPATA40" ENSG00000138587 "Meiosis specific nuclear structural 1" Q8NEH6 15 56421544-56465137 "Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 21.2;testis: 48.2" "Group enriched" "Detected in many" 5 "Early spermatids: 504.6;Endometrial ciliated cells: 256.5;Respiratory ciliated cells: 232.5;Spermatocytes: 249.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039975, HPA040382" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nuclear speckles" "HPA039975: AB_10793858, HPA040382: AB_10794740" "unprognostic (7.78e-2)" "unprognostic (2.54e-2)" "unprognostic (1.19e-1)" "unprognostic (5.07e-2)" "unprognostic (2.25e-1)" "unprognostic (6.62e-2)" "unprognostic (1.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.13e-2)" "unprognostic (2.05e-2)" "unprognostic (6.63e-2)" "unprognostic (1.06e-1)" "unprognostic (1.12e-3)" "unprognostic (8.20e-3)" "unprognostic (1.15e-1)" "unprognostic (2.72e-2)" "unprognostic (7.71e-2)" 1.9 1.4 2.6 1.6 2.4 4.6 3.1 10.1 2.9 3.5 12.3 1.9 2.3 3.6 1.3 2.7 21.2 3.3 2.5 2.2 2.4 10.5 1.9 3.4 1.3 7.2 6.8 4.0 2.4 0.6 3.5 1.6 5.1 2.3 2.0 4.7 2.0 1.7 1.0 1.4 2.1 1.3 6.1 1.4 2.2 48.2 2.7 5.6 2.9 1.1 1.2 1.3 2.5 3.9 32.1 7.4 3.8 11.3 3.1 6.7 0.7 7.6 4.4 8.8 18.6 10.5 15.0 17.8 9.4 3.2 12.8 12.3 4.7 4.4 17.9 0.0 1.9 22.9 8.8 1.8 1.1 7.9 2.4 2.7 0.2 17.9 2.6 3.7 1.6 6.8 5.2 0.0 7.6 4.2 0.3 9.8 1.2 16.4 4.3 15.0 22.6 0.2 8.7 6.1 29.5 8.9 12.7 3.8 13.6 0.9 9.1 12.1 0.7 12.0 13.6 11.6 18.8 3.6 11.9 0.3 13.4 18.3 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.4 10.1 2.9 2.2 2.4 7.2 6.8 5.1 6.1 2.7 3.9 0.7 0.0 4.7 1.0 0.8 3.3 8.8 9.3 1.8 10.5 4.7 8.3 6.0 4.3 28.3 35.0 25.0 1.8 0.2 3.7 11.7 10.9 504.6 256.5 7.8 2.0 1.2 3.0 4.9 1.9 3.9 14.0 5.1 7.2 0.0 11.0 6.8 0.4 7.0 15.2 3.7 4.5 10.2 1.0 5.5 60.8 12.8 2.0 0.0 0.0 0.8 12.4 0.0 1.5 2.8 1.2 0.1 8.6 0.5 3.0 0.3 12.3 232.5 32.6 0.0 21.6 6.5 249.6 25.0 7.1 1.4 0.5 1.0 6.4 6.0 3.5 MNX1 "HB9, HLXB9, HOXHB9, SCRA1" ENSG00000130675 "Motor neuron and pancreas homeobox 1" P50219 7 156994051-157010663 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 7.2;pancreas: 16.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 6.6;Enteroendocrine cells: 25.1;Intestinal goblet cells: 19.7;Paneth cells: 7.0;Proximal enterocytes: 7.3;Undifferentiated cells: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 17.2;BEWO: 12.7;EFO-21: 16.2;HEK 293: 13.2;RPMI-8226: 37.6;SCLC-21H: 19.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 39 "spinal cord: 3.9" HPA071717 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Cytosol" "HPA071717: AB_2686437" "unprognostic (2.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.87e-2)" "unprognostic (3.72e-3)" "unprognostic (8.85e-2)" "unprognostic (1.08e-2)" "unprognostic (2.07e-1)" "unprognostic (4.07e-2)" "unprognostic (5.06e-2)" "unprognostic (8.62e-4)" "unprognostic (1.00e-2)" "unprognostic (3.35e-2)" "unprognostic (2.23e-5)" "unprognostic (1.67e-3)" "unprognostic (5.80e-2)" "unprognostic (5.58e-2)" "unprognostic (1.08e-1)" 0.1 0.0 0.5 0.3 0.5 0.1 0.0 0.3 0.6 0.0 0.0 3.7 7.2 0.0 0.0 0.2 0.0 0.8 0.0 0.5 0.2 0.1 0.0 0.0 0.0 1.3 0.3 0.0 16.3 0.0 2.6 0.0 0.9 0.3 3.0 0.0 1.1 0.0 0.0 0.1 6.1 0.0 0.8 0.0 2.2 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.4 5.8 0.0 17.2 0.0 0.0 12.7 0.0 0.0 0.1 0.0 7.6 2.5 1.4 16.2 0.0 0.5 0.3 3.0 2.3 1.3 2.2 13.2 0.0 1.5 3.6 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 0.0 6.1 5.7 2.9 0.0 10.1 0.9 0.2 0.0 1.7 1.1 0.0 2.5 37.6 6.5 0.6 19.3 0.0 2.5 2.2 0.4 0.1 5.4 4.4 0.0 0.0 0.0 0.0 0.0 5.3 2.9 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 0.6 0.5 0.2 1.3 0.3 0.9 0.8 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 1.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.0 4.4 1.3 0.1 0.0 0.1 25.1 0.0 0.0 3.0 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 19.7 0.0 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 3.1 7.0 0.0 0.4 0.0 7.3 0.1 0.0 0.0 0.0 0.0 0.2 1.8 0.8 0.0 0.0 0.0 0.2 0.0 13.6 0.0 MPDZ MUPP1 ENSG00000107186 "Multiple PDZ domain crumbs cell polarity complex component" O75970 9 13105706-13279692 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 85.7" "Cell type enhanced" "Detected in many" "Astrocytes: 121.5;Excitatory neurons: 213.6;Inhibitory neurons: 271.3;Oligodendrocyte precursor cells: 158.8;Oligodendrocytes: 279.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 58.1;HUVEC TERT2: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013512, HPA020255, HPA026686" Enhanced NA NA "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB013512: AB_2533517, HPA020255: AB_1854073, HPA026686: AB_1854074" "unprognostic (1.55e-1)" "unprognostic (4.21e-3)" "unprognostic (4.09e-3)" "unprognostic (1.68e-1)" "unprognostic (4.28e-2)" "unprognostic (1.03e-1)" "prognostic favorable (8.68e-4)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (2.50e-1)" "prognostic favorable (7.40e-4)" "unprognostic (1.54e-1)" "unprognostic (2.59e-3)" "unprognostic (1.32e-3)" "unprognostic (2.50e-1)" "unprognostic (1.58e-1)" "unprognostic (9.74e-2)" 22.7 9.9 18.0 5.3 23.2 0.2 13.2 20.3 20.6 14.3 21.7 16.1 2.8 17.8 15.3 7.6 17.5 11.7 29.8 18.0 20.4 18.8 85.7 11.1 3.9 19.8 22.4 25.6 4.6 11.3 10.7 24.7 20.3 19.2 5.3 33.0 6.3 23.2 19.9 3.8 6.4 18.6 21.4 11.1 7.6 11.5 17.7 4.3 11.7 31.3 1.8 12.6 9.9 35.3 16.1 21.2 58.1 26.0 39.2 35.4 11.8 15.9 16.4 13.8 13.1 0.0 0.0 0.0 4.5 39.6 14.2 0.3 17.3 8.8 22.3 0.0 10.2 10.5 21.9 3.9 20.8 0.1 5.4 26.5 3.6 9.7 6.6 35.3 53.5 0.0 0.3 0.1 12.5 4.2 0.0 0.2 24.9 0.0 9.0 0.0 14.2 0.0 13.7 8.5 7.2 26.9 12.6 2.8 15.5 39.7 8.1 0.1 42.8 14.1 2.7 4.7 12.4 0.0 0.0 0.0 6.8 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 23.2 20.3 20.6 18.0 20.4 19.8 22.4 20.3 21.4 17.7 35.3 70.9 32.1 7.9 121.5 0.2 5.1 10.1 4.8 3.4 30.9 8.6 15.6 109.7 1.5 14.7 7.3 39.6 16.1 0.4 0.1 1.9 4.2 4.2 27.0 12.4 44.6 1.8 2.1 213.6 2.0 22.9 27.4 1.5 6.3 1.3 39.5 42.5 74.4 5.8 26.9 271.3 0.2 6.1 0.6 6.8 3.7 24.2 0.9 17.8 60.9 0.6 40.2 0.0 158.8 279.6 1.8 0.0 33.8 0.1 12.9 0.0 16.4 36.6 25.4 39.5 35.1 40.8 6.7 13.9 0.1 4.0 10.8 0.8 7.6 0.0 4.7 MRAS "M-RAs, R-RAS3, RRAS3" ENSG00000158186 "Muscle RAS oncogene homolog" O14807 3 138347648-138405534 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 202.3;heart muscle: 132.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 121.7;Distal tubular cells: 58.7;Theca cells: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "non-classical monocyte: 25.0" "Lineage enriched" "Detected in many" 9 "monocytes: 25.0" "Cell line enhanced" "Detected in many" "BJ: 92.9;EFO-21: 113.7;fHDF/TERT166: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042728 Approved Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol Vesicles "HPA042728: AB_10796582" "unprognostic (1.96e-1)" "unprognostic (2.95e-1)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.69e-1)" "unprognostic (5.32e-2)" "unprognostic (8.96e-2)" "unprognostic (3.85e-3)" "unprognostic (1.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (3.18e-3)" "unprognostic (1.78e-2)" "unprognostic (6.25e-2)" "unprognostic (2.21e-1)" "unprognostic (4.23e-2)" 91.9 67.7 112.7 10.8 130.6 1.7 46.7 118.2 105.5 17.3 48.9 24.2 3.3 28.7 7.1 7.9 26.4 12.0 132.9 105.6 132.8 22.9 5.5 18.4 5.2 126.1 135.9 48.6 5.7 8.2 17.7 10.6 112.9 15.3 4.1 15.9 13.4 15.0 80.4 12.2 8.7 23.2 110.3 12.2 12.0 9.6 202.3 4.9 26.4 48.0 3.3 29.1 12.1 97.8 0.8 7.9 15.8 24.5 59.6 29.2 40.0 92.9 16.0 7.3 8.2 3.3 3.1 0.3 113.7 70.4 18.6 0.1 9.0 1.8 6.1 7.7 3.1 0.5 4.8 20.1 15.9 0.0 1.9 41.5 5.9 0.7 1.4 13.6 1.3 0.0 10.7 0.8 31.4 3.7 0.0 20.4 19.1 0.0 2.7 1.1 33.8 0.2 30.4 2.0 18.6 42.0 62.8 0.7 45.9 10.9 16.1 37.7 0.6 23.7 25.3 24.3 2.4 0.1 1.0 1.2 21.4 0.1 11.4 0.2 2.1 0.0 0.0 4.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.3 0.8 25.0 0.1 0.0 0.8 112.7 130.6 118.2 105.5 105.6 132.8 126.1 135.9 112.9 110.3 202.3 97.8 8.9 9.6 1.5 54.2 0.8 2.2 3.0 3.4 1.2 5.6 28.8 34.8 121.7 2.8 3.5 9.2 10.4 20.1 0.2 0.0 58.7 8.6 11.6 1.0 21.4 14.5 1.8 0.0 25.5 3.2 3.2 23.0 2.0 1.5 6.3 35.2 12.8 1.6 26.3 28.6 20.6 0.0 2.0 15.1 18.4 40.0 23.3 18.2 28.4 20.6 12.2 24.3 0.0 28.6 11.0 3.8 0.0 34.3 0.1 3.3 0.0 27.5 1.3 9.6 6.6 20.8 18.9 7.3 18.6 0.4 1.0 14.4 0.8 59.1 0.0 0.6 MSMO1 "DESP4, ERG25, SC4MOL" ENSG00000052802 "Methylsterol monooxygenase 1" Q15800 4 165327667-165343164 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 575.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 532.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 416.2;Karpas-707: 412.3;RPTEC TERT1: 399.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055073, HPA056127" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA055073: , HPA056127: AB_2683045" "unprognostic (5.76e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.35e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-2)" "unprognostic (7.14e-2)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (3.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (9.21e-4)" "unprognostic (2.39e-1)" "unprognostic (1.56e-2)" "unprognostic (3.54e-1)" "unprognostic (1.40e-1)" 18.3 95.2 36.7 20.9 48.2 10.4 66.2 45.1 47.5 57.1 37.4 39.2 75.7 19.1 97.0 145.7 20.9 21.7 18.5 43.9 59.2 52.6 575.6 70.3 20.7 90.5 58.4 25.7 22.6 42.9 18.4 22.9 78.6 58.9 32.9 26.1 34.7 12.1 5.5 82.5 38.1 16.5 45.0 11.0 31.5 52.8 48.4 13.4 22.4 6.5 27.0 20.2 67.0 61.1 89.1 21.7 198.8 36.4 97.7 312.0 37.5 35.3 159.0 44.7 123.4 41.5 372.9 43.4 20.6 43.1 416.2 71.7 101.6 366.3 49.4 37.7 63.0 20.0 20.0 127.6 194.9 35.8 26.8 192.6 237.6 163.6 100.6 61.1 58.8 55.7 35.3 412.3 74.6 45.7 32.6 58.2 115.6 46.9 21.0 16.8 21.8 132.3 399.5 102.5 39.7 30.0 54.5 77.9 33.9 121.7 36.1 44.7 67.6 20.6 36.1 18.5 24.7 75.9 86.5 58.6 43.9 36.0 28.5 13.7 8.6 8.8 34.0 11.6 25.4 40.6 31.8 31.4 15.0 37.6 34.3 35.6 6.1 24.9 20.5 19.3 31.0 29.2 36.7 48.2 45.1 47.5 43.9 59.2 90.5 58.4 78.6 45.0 48.4 61.1 16.9 51.3 168.0 70.5 28.9 36.1 70.1 189.2 21.6 33.8 81.9 23.0 10.7 40.0 160.0 69.9 27.1 55.6 20.7 130.8 35.2 67.9 6.4 27.6 12.2 30.4 60.7 53.9 33.6 71.7 87.0 24.1 35.2 44.4 47.7 83.0 27.8 532.0 28.3 35.3 22.8 72.8 170.9 28.0 11.5 7.0 24.8 18.3 32.0 10.3 23.6 27.2 17.5 42.7 49.6 86.8 85.7 18.8 10.9 138.3 46.0 38.4 103.2 50.4 19.7 5.6 35.1 8.7 15.4 84.6 115.1 123.0 22.3 136.1 36.9 129.0 MSX1 "HOX7, HYD1, OFC5" ENSG00000163132 "Msh homeobox 1" P28360 4 4859665-4863936 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 57.0;choroid plexus: 98.0" "Group enriched" "Detected in many" 6 "Adipocytes: 118.4;Endometrial ciliated cells: 364.0;Glandular and luminal cells: 462.0" "Cancer enriched" "Detected in all" 17 "endometrial cancer: 246.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 47.9;EFO-21: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB026198, HPA063895, HPA073604" Enhanced Supported Nucleoplasm NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB026198: , HPA063895: AB_2685145, HPA073604: AB_2686617" "unprognostic (1.12e-1)" "unprognostic (1.93e-2)" "unprognostic (3.39e-2)" "prognostic favorable (1.64e-7)" "unprognostic (9.13e-2)" "unprognostic (1.16e-3)" "unprognostic (4.07e-3)" "unprognostic (3.81e-2)" "unprognostic (1.48e-2)" "unprognostic (2.21e-3)" "unprognostic (4.78e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.18e-5)" "unprognostic (4.35e-2)" "unprognostic (2.06e-1)" "unprognostic (2.34e-3)" "unprognostic (1.33e-2)" 18.4 6.0 12.2 0.7 11.8 0.2 12.8 12.2 16.9 57.0 98.0 1.8 0.5 17.5 0.3 0.9 9.6 1.3 10.3 18.8 12.2 2.9 0.5 4.3 0.6 17.2 11.8 3.5 2.3 0.4 21.1 4.1 11.8 5.5 0.1 0.6 8.8 3.6 20.1 5.2 1.1 3.2 15.1 4.5 2.0 0.7 13.0 0.2 9.2 2.0 0.4 11.2 14.5 12.3 2.5 1.5 0.5 2.8 8.0 5.1 8.9 6.1 2.8 3.5 1.7 47.9 15.3 0.3 21.4 4.4 17.0 0.1 10.6 0.0 1.2 2.0 12.2 0.1 8.0 17.4 0.6 0.1 1.4 1.0 0.8 2.6 0.9 1.1 0.8 4.1 7.9 0.3 1.9 1.2 1.3 2.4 0.2 0.7 11.1 6.4 6.4 0.6 0.2 1.5 0.4 0.3 5.4 0.3 4.0 0.8 0.9 2.1 2.0 4.1 9.1 13.0 9.9 1.0 0.9 5.7 2.6 3.1 4.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 12.2 11.8 12.2 16.9 18.8 12.2 17.2 11.8 11.8 15.1 13.0 12.3 118.4 0.0 0.0 17.3 0.5 7.1 2.4 0.3 4.6 0.8 8.6 24.3 5.5 0.0 0.0 0.0 4.2 0.3 1.6 3.9 0.0 0.2 0.4 364.0 35.7 48.1 0.0 0.0 1.1 0.9 0.1 34.8 1.1 462.0 0.0 1.1 5.7 0.2 0.5 0.0 1.2 2.5 0.0 0.6 8.8 0.0 1.2 4.4 16.0 3.7 0.0 0.7 0.0 1.0 0.3 0.3 0.1 0.4 1.6 3.3 0.6 0.5 0.0 0.7 0.0 13.6 18.2 0.8 1.5 2.6 4.7 0.3 4.8 14.6 2.6 2.0 MSX2 "CRS2, FPP, HOX8, MSH, PFM, PFM1" ENSG00000120149 "Msh homeobox 2" P35548 5 174724582-174730896 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Osteogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 25.8;placenta: 33.6;urinary bladder: 17.5" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 162.6;Endometrial ciliated cells: 65.7;Glandular and luminal cells: 62.2;Syncytiotrophoblasts: 233.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 18.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 322.0" "Region enriched" "Detected in some" 5 "cerebellum: 6.2" "Low region specificity" "Detected in many" HPA005652 Uncertain Supported "Nuclear speckles" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" "HPA005652: AB_1079418" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.50e-2)" "unprognostic (1.22e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (6.93e-4)" "unprognostic (2.08e-2)" "unprognostic (1.60e-1)" "unprognostic (2.51e-2)" "unprognostic (7.26e-2)" "unprognostic (1.36e-4)" "unprognostic (7.64e-3)" "unprognostic (5.06e-2)" "unprognostic (2.12e-6)" "unprognostic (1.43e-2)" 2.1 0.3 0.7 0.5 1.0 0.0 8.1 4.3 1.1 2.7 1.1 0.9 0.3 6.8 0.0 0.6 0.9 0.9 1.6 1.2 1.4 0.3 0.0 0.8 0.1 7.8 1.3 0.2 0.4 25.8 0.3 33.6 4.1 2.5 0.1 0.0 0.8 0.8 1.9 6.9 0.8 1.4 5.4 0.8 2.8 5.6 1.3 0.1 0.7 1.8 0.1 17.5 1.8 5.4 0.4 4.0 1.1 3.2 0.0 0.0 322.0 2.2 3.6 0.7 0.1 56.6 23.0 0.0 8.6 0.2 19.6 6.2 17.6 6.4 0.2 0.0 10.7 0.0 1.4 0.0 2.4 0.0 3.0 3.7 4.5 3.1 3.5 0.0 0.0 0.0 0.0 0.0 5.0 27.7 0.0 0.4 2.5 38.3 8.5 0.0 8.8 0.1 4.0 35.3 0.0 2.5 0.0 43.0 2.9 69.6 25.7 0.2 0.0 1.1 5.5 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 4.3 1.1 1.2 1.4 7.8 1.3 4.1 5.4 1.3 5.4 1.5 0.0 0.0 2.3 0.0 9.6 2.4 0.1 3.4 0.2 15.8 18.9 1.7 0.0 0.1 0.0 0.0 162.6 0.2 0.3 0.0 0.6 0.2 65.7 4.9 0.7 0.0 0.0 0.0 0.0 13.9 5.3 5.1 62.2 4.5 0.1 0.4 0.0 11.3 0.0 0.0 1.9 0.0 0.6 2.9 0.6 0.0 1.0 1.8 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.1 2.3 1.9 0.1 0.1 0.0 0.0 8.9 4.8 1.4 4.5 2.0 11.4 233.8 1.0 0.6 1.2 9.8 MTHFD1 "MTHFC, MTHFD" ENSG00000100714 "Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1" 14 64388031-64463457 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 356.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 142.9;Proximal tubular cells: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000704, HPA001290, HPA015006, HPA050052" Approved Enhanced Cytosol NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA000704: AB_1079424, HPA001290: AB_1854177, HPA015006: AB_1854178, HPA050052: AB_2680998" "unprognostic (3.58e-2)" "unprognostic (5.50e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (7.01e-2)" "unprognostic (8.85e-3)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.84e-1)" "prognostic favorable (5.93e-5)" "unprognostic (2.45e-2)" "unprognostic (1.75e-1)" "unprognostic (7.30e-2)" "unprognostic (2.29e-2)" 56.4 18.0 8.6 20.0 17.4 27.0 29.8 8.3 12.3 16.9 15.0 23.3 19.7 16.1 9.9 25.1 16.0 13.1 28.1 12.9 8.1 55.3 356.9 15.4 23.6 7.5 7.8 24.9 23.8 27.5 9.2 13.3 7.0 12.9 27.5 3.6 15.6 13.8 64.1 17.1 18.9 20.0 7.2 14.5 17.9 4.7 8.9 30.2 20.5 61.9 27.7 18.6 16.6 8.3 294.1 164.9 58.5 143.6 70.5 53.4 95.7 106.4 83.3 148.1 147.4 161.2 144.2 103.3 49.6 67.1 68.3 146.0 177.6 111.2 160.4 107.3 117.9 122.2 143.5 131.8 50.6 104.5 81.2 43.0 37.3 124.3 66.4 57.5 93.1 98.1 108.5 98.7 114.7 270.1 179.9 62.3 118.0 186.5 160.4 138.3 201.2 114.4 110.5 160.9 128.7 49.0 183.7 111.4 58.3 54.0 164.4 58.6 51.5 115.1 184.1 102.2 134.2 58.8 65.6 177.9 107.4 125.2 134.8 0.4 11.7 0.1 9.7 19.5 13.0 27.0 10.1 12.3 17.7 15.3 7.8 10.7 0.9 17.8 16.7 4.0 19.5 12.2 8.6 17.4 8.3 12.3 12.9 8.1 7.5 7.8 7.0 7.2 8.9 8.3 8.1 19.2 23.5 15.0 16.2 13.8 14.2 14.7 13.6 0.0 9.8 8.1 43.9 15.7 19.5 16.5 0.0 30.6 10.8 7.9 41.1 16.9 1.4 6.8 11.7 12.3 3.0 42.3 19.5 10.3 30.9 14.9 15.3 8.7 50.7 27.2 12.8 142.9 25.3 0.0 15.6 14.3 2.0 13.0 11.0 1.5 13.1 12.3 14.2 8.4 13.3 0.0 8.2 14.1 10.9 11.7 6.3 13.2 24.1 10.2 8.2 75.3 11.5 0.0 19.7 13.1 19.3 0.9 8.9 19.5 10.7 9.9 16.6 21.4 24.6 12.7 MTHFR ENSG00000177000 "Methylenetetrahydrofolate reductase" P42898 1 11785723-11806455 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 44.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063389, HPA076180, HPA077255" Enhanced Approved "Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "HPA063389: AB_2685001, HPA076180: , HPA077255: " "unprognostic (3.25e-2)" "unprognostic (8.19e-2)" "unprognostic (4.48e-2)" "unprognostic (2.11e-2)" "unprognostic (1.34e-1)" "prognostic favorable (3.97e-5)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.75e-2)" "unprognostic (2.85e-1)" "unprognostic (8.69e-2)" "prognostic favorable (4.81e-5)" "unprognostic (3.10e-1)" "prognostic favorable (2.12e-4)" "unprognostic (2.35e-3)" "unprognostic (2.94e-1)" "unprognostic (4.14e-2)" "unprognostic (1.80e-2)" 12.3 11.3 7.1 10.8 10.3 28.9 10.2 12.8 8.8 9.0 5.0 11.1 10.8 8.9 53.5 10.3 12.3 10.1 23.9 10.4 6.2 12.8 13.1 16.8 12.3 9.9 7.0 19.7 11.4 6.6 17.7 7.1 9.4 10.2 8.7 12.6 6.8 6.7 17.9 13.4 14.7 10.8 5.1 18.3 14.6 10.9 8.0 7.9 16.3 16.8 12.2 10.3 7.9 8.9 2.2 9.4 10.9 12.3 10.2 15.1 2.0 5.2 14.6 6.0 5.1 8.1 13.2 18.0 3.6 7.5 16.3 4.1 8.1 7.7 2.4 9.3 6.8 13.4 13.3 3.2 13.7 7.4 16.4 13.6 6.1 8.0 6.4 10.0 10.7 17.2 44.1 11.0 6.7 3.3 8.2 3.5 3.6 9.5 3.0 8.9 6.0 20.3 8.8 11.7 10.5 17.6 8.1 7.8 10.9 6.2 12.9 11.7 8.5 6.0 4.9 7.2 1.6 6.4 9.4 32.8 7.6 16.8 5.6 0.7 2.3 1.1 2.7 4.3 0.9 1.6 0.8 1.4 1.7 2.3 1.2 1.4 2.5 2.0 6.1 0.9 0.6 1.6 7.1 10.3 12.8 8.8 10.4 6.2 9.9 7.0 9.4 5.1 8.0 8.9 15.9 25.6 48.0 8.1 18.3 8.4 6.8 11.9 15.9 0.0 17.9 10.8 37.0 11.5 13.0 27.6 0.0 5.1 6.0 44.2 1.9 8.9 18.2 32.0 25.8 16.9 12.1 29.5 15.8 25.3 3.3 21.0 52.5 55.5 8.2 10.7 37.5 23.4 22.2 0.0 15.2 18.0 6.1 39.3 39.9 42.4 18.3 32.1 12.4 16.9 26.5 0.0 20.6 9.0 13.3 21.9 20.6 9.1 10.3 10.2 36.0 17.2 12.3 0.0 19.7 22.8 23.3 6.8 5.2 15.0 9.2 2.9 10.6 21.3 18.6 9.6 MTOR "FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1" ENSG00000198793 "Mechanistic target of rapamycin kinase" P42345 1 11106535-11262551 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB069425, HPA071227" Approved Approved Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "CAB069425: , HPA071227: AB_2686367" "unprognostic (3.18e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (2.45e-3)" "unprognostic (5.50e-2)" "unprognostic (2.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "unprognostic (8.24e-3)" "unprognostic (3.48e-2)" "unprognostic (1.88e-1)" "prognostic favorable (1.49e-5)" "unprognostic (1.27e-1)" "unprognostic (2.45e-1)" "unprognostic (6.60e-2)" "unprognostic (7.55e-2)" 16.3 19.4 18.2 13.5 19.0 14.0 16.8 18.4 20.1 15.2 18.6 22.8 11.0 17.5 21.8 18.3 14.6 9.0 23.6 19.7 17.7 24.1 27.6 15.2 15.3 16.5 21.2 14.2 18.3 20.6 21.8 11.8 18.4 19.8 16.0 26.9 16.5 13.8 36.4 17.1 19.6 13.8 14.6 21.2 18.7 33.8 22.7 19.2 17.8 17.8 15.9 17.1 14.9 18.7 28.5 25.2 33.3 25.4 39.4 18.6 16.6 23.4 22.3 30.6 29.9 26.0 25.5 31.4 19.6 27.8 18.8 33.1 45.3 35.8 39.3 25.2 33.2 41.7 53.8 33.4 24.7 41.1 29.7 24.0 26.8 43.7 44.0 14.5 39.3 29.6 47.4 26.1 21.6 32.4 28.5 31.2 25.3 29.6 23.5 28.2 39.2 21.0 27.2 25.3 33.4 24.5 50.1 26.8 31.2 36.5 21.8 24.0 42.3 26.5 23.9 20.5 31.8 25.5 25.5 60.5 19.1 43.6 28.6 0.3 1.1 1.3 1.9 2.4 1.6 1.4 1.1 1.0 1.6 1.1 1.3 1.1 0.8 1.1 1.3 1.2 2.4 1.0 18.2 19.0 18.4 20.1 19.7 17.7 16.5 21.2 18.4 14.6 22.7 18.7 9.2 16.0 11.8 40.8 10.0 3.4 5.2 7.6 8.6 0.0 7.7 7.5 25.1 2.8 10.3 9.2 0.0 7.9 9.8 9.4 1.9 8.5 42.0 13.8 16.1 11.0 10.3 14.3 43.8 6.2 7.2 9.2 16.8 18.6 13.3 12.9 5.3 13.4 6.9 0.0 49.2 7.8 6.1 8.2 4.1 36.1 7.8 9.1 8.8 36.5 9.2 0.0 10.3 38.2 37.4 10.4 5.4 8.2 17.2 8.9 7.0 4.5 6.3 0.0 39.5 11.4 12.1 49.3 37.4 15.6 5.7 9.9 9.8 15.3 10.0 5.7 MTR cblG ENSG00000116984 "5-methyltetrahydrofolate-homocysteine methyltransferase" Q99707 1 236795260-236921278 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Methyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 100.0;Glandular and luminal cells: 130.9;Inhibitory neurons: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044474, HPA054915" Approved Supported Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA044474: AB_10966696, HPA054915: AB_2732589" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (6.96e-2)" "unprognostic (1.99e-1)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "unprognostic (4.87e-1)" "unprognostic (1.02e-1)" "unprognostic (2.48e-2)" "unprognostic (3.34e-1)" "unprognostic (5.73e-2)" "unprognostic (1.63e-1)" "unprognostic (1.67e-2)" "unprognostic (8.84e-3)" "unprognostic (1.88e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (8.10e-2)" 9.1 6.6 4.3 6.9 5.4 4.6 8.0 5.2 5.4 10.1 6.5 11.1 4.8 10.2 10.5 5.0 11.9 8.9 15.0 4.9 4.6 12.7 6.0 7.1 8.1 6.7 5.3 14.6 13.0 20.2 6.4 11.6 6.9 7.6 5.0 5.6 6.4 9.1 16.6 9.3 7.1 8.7 4.8 9.4 9.0 9.0 4.8 10.0 13.4 18.1 7.0 10.3 7.6 6.5 17.6 11.0 13.0 8.8 22.6 20.3 15.3 14.9 14.8 18.8 19.0 12.6 12.5 40.0 13.2 16.6 8.7 10.6 18.4 13.1 20.4 19.8 13.7 23.7 14.2 18.3 15.1 37.2 13.3 28.9 7.0 22.9 17.9 11.5 22.3 19.8 33.1 16.4 13.1 10.1 19.6 10.3 16.2 12.9 5.4 20.9 24.8 24.2 11.2 21.3 11.1 27.8 17.7 11.9 14.8 9.3 16.7 13.0 28.8 24.1 9.1 19.6 18.8 34.4 12.3 22.7 17.2 21.1 26.2 0.6 0.5 1.5 1.1 0.8 2.3 0.7 1.4 1.4 0.7 0.8 1.4 1.5 0.0 0.9 0.5 0.5 0.9 0.9 4.3 5.4 5.2 5.4 4.9 4.6 6.7 5.3 6.9 4.8 4.8 6.5 23.0 57.7 35.0 53.8 25.8 8.2 8.3 8.3 17.1 0.0 10.7 11.9 100.0 20.0 10.9 40.5 0.0 24.2 25.9 3.4 1.9 13.8 9.8 57.5 80.1 21.4 8.4 23.5 87.7 14.8 9.2 22.8 15.8 130.9 30.4 35.0 15.4 10.8 14.4 0.0 106.8 7.7 4.1 16.6 6.8 6.2 23.9 17.1 10.6 47.8 15.3 0.0 19.6 62.8 73.6 12.3 8.0 33.1 20.3 14.9 9.7 9.1 13.3 0.0 6.6 39.4 23.2 17.2 22.0 11.5 5.1 22.6 26.1 40.2 12.0 6.4 MTRR cblE ENSG00000124275 "5-methyltetrahydrofolate-homocysteine methyltransferase reductase" Q9UBK8 5 7851186-7906025 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.1;Late spermatids: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038113 Supported Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cytosol" "Intermediate filaments" "HPA038113: AB_10671520" "unprognostic (1.06e-1)" "unprognostic (1.08e-1)" "unprognostic (5.32e-2)" "unprognostic (1.17e-2)" "unprognostic (1.63e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.60e-4)" "unprognostic (2.56e-2)" "unprognostic (5.82e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (9.11e-3)" "unprognostic (3.44e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" 11.2 10.6 5.1 9.5 11.2 5.7 6.3 10.1 10.9 7.2 3.4 8.3 8.9 11.7 12.3 9.3 9.6 11.8 14.4 6.5 9.0 18.7 19.4 13.1 11.1 10.9 10.4 11.4 11.9 12.8 6.7 10.8 10.6 9.0 10.1 19.2 10.5 7.1 28.9 9.1 10.2 12.0 8.2 6.7 6.7 7.1 9.3 7.5 9.0 32.9 10.6 14.4 5.5 20.0 19.3 18.1 10.2 20.0 34.0 13.6 25.1 31.1 18.5 16.5 15.4 27.8 15.1 32.6 27.9 24.6 27.4 11.8 17.0 14.2 27.9 22.9 15.8 14.6 62.0 15.3 21.9 23.4 6.8 18.3 11.4 24.6 18.4 20.4 10.4 8.0 21.9 24.2 9.8 4.2 14.2 11.7 7.3 29.4 19.0 12.4 9.5 14.1 16.2 16.0 14.0 2.5 51.6 33.7 28.6 18.1 10.7 17.5 14.6 31.9 19.7 24.1 22.7 34.7 13.5 27.3 23.1 50.5 19.1 5.3 4.0 3.0 4.1 5.5 7.0 3.3 6.5 5.7 3.6 3.3 4.1 3.6 0.1 3.1 4.4 2.3 9.1 3.3 5.1 11.2 10.1 10.9 6.5 9.0 10.9 10.4 10.6 8.2 9.3 20.0 7.7 16.0 70.1 10.1 11.1 16.3 9.4 4.6 12.0 0.0 9.7 5.1 12.9 5.7 9.0 9.2 0.0 9.9 11.4 11.0 21.5 10.2 50.1 10.0 10.7 8.0 9.6 12.4 25.4 5.5 8.9 11.8 9.2 6.7 10.2 6.5 8.6 19.3 7.7 0.0 20.8 9.1 0.0 11.1 9.4 99.2 10.5 9.7 1.8 15.0 8.1 0.0 7.2 20.1 50.9 7.2 6.0 11.7 26.5 14.3 8.7 28.9 10.1 0.0 6.6 10.7 10.1 17.4 13.1 10.5 20.6 11.2 13.8 11.8 9.4 8.7 MUC1 "ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 485.8;stomach 1: 1064.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1370.0;Collecting duct cells: 491.1;Exocrine glandular cells: 1164.9;Gastric mucus-secreting cells: 640.6;Pancreatic endocrine cells: 1074.8;Respiratory ciliated cells: 555.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Group enriched" "Detected in many" 6 "CAPAN-2: 1146.1;OE19: 548.3;RPTEC TERT1: 870.2;T-47d: 383.6" "Not detected" "Not detected" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA 4000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" 15.2 6.3 5.3 21.9 5.7 9.4 78.2 4.7 8.6 194.2 4.7 176.0 21.4 40.2 61.6 209.9 120.0 125.8 6.8 5.1 5.7 485.8 3.9 321.5 1.8 7.8 6.3 9.8 358.5 1.0 14.1 3.3 6.0 43.9 103.6 1.3 135.0 34.4 1.9 20.6 35.2 20.0 6.1 5.4 1064.7 47.9 6.8 1.2 54.8 0.7 18.8 102.0 50.0 5.2 15.3 8.2 5.1 4.8 3.9 4.2 1.7 5.6 12.2 6.2 15.2 0.2 1146.1 0.0 81.9 9.5 2.7 23.2 1.0 0.3 1.8 10.4 0.8 1.8 101.5 0.0 2.4 0.4 36.1 9.5 2.1 2.8 2.2 12.7 2.1 1.9 9.2 15.4 4.3 120.0 1.6 1.2 3.5 548.3 2.1 2.3 0.6 29.3 870.2 0.9 5.1 2.1 28.0 48.3 1.5 4.1 383.6 5.6 2.2 3.9 6.7 10.5 1.2 17.7 9.8 0.2 5.9 1.1 1.4 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.1 5.3 5.7 4.7 8.6 5.1 5.7 7.8 6.3 6.0 6.1 6.8 5.2 2.3 432.7 1370.0 5.9 6.4 0.6 18.5 126.4 0.0 1.3 219.2 48.5 0.4 327.5 374.9 491.1 4.2 0.5 1.5 271.8 35.2 177.3 32.7 245.2 28.8 8.0 30.6 1.3 0.3 1164.9 1.1 7.0 640.6 282.8 48.0 0.3 1.8 0.9 0.2 1.7 0.3 351.5 164.8 2.2 1.0 81.0 2.5 7.2 5.4 1.0 24.3 1.7 0.0 0.5 0.1 1074.8 60.5 1.5 1.3 16.3 6.8 1.3 555.3 0.2 0.0 2.0 22.0 5.8 0.8 3.5 1.1 0.3 10.3 0.1 220.8 154.5 MUSK ENSG00000030304 "Muscle associated receptor tyrosine kinase" O15146 9 110668779-110806558 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Developmental protein, Kinase, Muscle protein, Receptor, Transferase, Tyrosine-protein kinase" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.2;skeletal muscle: 4.1" "Cell type enhanced" "Detected in some" "Late spermatids: 4.8;Leydig cells: 5.3;Oligodendrocytes: 17.0;Peritubular cells: 19.5;Skeletal myocytes: 23.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "LHCN-M2: 24.7;RH-30: 23.7" "Region enhanced" "Detected in some" "basal ganglia: 5.0" "Not detected" "Not detected" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (6.12e-2)" "unprognostic (9.01e-2)" "unprognostic (5.39e-2)" "unprognostic (3.66e-1)" "unprognostic (3.14e-1)" "unprognostic (1.20e-2)" "unprognostic (1.50e-2)" "unprognostic (2.46e-1)" "unprognostic (3.13e-1)" "unprognostic (7.58e-2)" "unprognostic (6.03e-5)" "unprognostic (4.58e-2)" "unprognostic (1.62e-1)" "unprognostic (9.67e-2)" "unprognostic (5.11e-2)" 0.1 0.2 1.5 1.7 3.0 0.0 0.0 0.8 1.5 0.0 1.6 1.9 1.1 0.0 0.0 1.4 0.0 1.1 1.5 1.2 1.1 0.0 0.3 1.0 0.6 2.7 6.2 0.1 0.1 0.0 0.0 0.3 1.7 0.2 2.5 0.0 0.1 0.0 4.1 0.1 2.4 0.5 2.9 0.0 1.3 1.6 2.0 0.1 0.0 2.0 2.0 1.2 0.0 4.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.5 0.0 0.2 0.0 23.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 3.0 0.8 1.5 1.2 1.1 2.7 6.2 1.7 2.9 2.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.0 0.3 0.1 0.0 0.0 1.3 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 4.8 5.3 0.0 0.0 1.9 0.0 0.0 0.0 2.5 17.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.1 0.5 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 MVD MPD ENSG00000167508 "Mevalonate diphosphate decarboxylase" P53602 16 88651935-88663161 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 147.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041404, HPA048250" Uncertain Approved "Cell Junctions,Cytosol" NA NA 170000 "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "Cell Junctions" "HPA041404: AB_2677457, HPA048250: AB_2680329" "unprognostic (1.67e-1)" "unprognostic (3.05e-1)" "unprognostic (2.42e-1)" "prognostic favorable (2.17e-4)" "unprognostic (1.89e-1)" "unprognostic (9.56e-2)" "unprognostic (9.26e-3)" "unprognostic (8.33e-2)" "unprognostic (6.68e-2)" "unprognostic (5.47e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-2)" "unprognostic (1.19e-3)" "unprognostic (4.12e-2)" "unprognostic (1.69e-1)" "unprognostic (2.11e-1)" "unprognostic (5.00e-2)" 20.3 51.1 24.2 15.7 27.5 7.0 16.4 26.2 37.5 30.5 19.3 32.3 35.1 20.3 2.2 77.8 13.5 4.9 22.8 24.7 27.8 28.8 78.8 31.0 12.3 32.4 27.8 19.6 25.3 8.3 18.9 6.3 39.3 23.5 4.2 3.4 25.1 6.5 27.2 52.3 26.6 5.7 24.0 24.6 31.5 42.3 24.7 7.0 21.1 8.3 6.8 17.6 36.9 25.6 50.6 34.2 52.4 33.1 18.1 38.7 29.5 25.1 26.0 17.7 14.6 86.1 119.7 24.4 39.8 15.7 63.7 72.8 25.0 133.1 4.9 15.7 38.3 17.8 18.2 127.0 35.9 11.6 11.8 30.9 24.6 46.6 13.5 8.7 18.0 58.0 51.7 13.1 10.2 115.9 39.3 56.6 61.5 17.7 31.3 40.2 15.0 62.3 49.8 33.0 52.2 17.9 62.0 13.3 18.5 11.4 67.8 51.3 39.0 14.7 29.8 27.2 14.2 34.9 17.6 83.2 17.9 55.7 25.7 5.6 12.6 2.4 26.8 13.7 20.4 16.1 18.0 17.9 15.0 22.6 13.2 16.6 1.8 28.3 15.4 28.0 20.4 15.4 24.2 27.5 26.2 37.5 24.7 27.8 32.4 27.8 39.3 24.0 24.7 25.6 17.2 25.6 48.2 22.2 21.5 15.2 12.9 106.3 4.0 27.2 26.5 14.1 16.7 21.5 56.9 20.2 6.2 20.2 79.6 117.5 25.4 30.8 61.6 17.7 10.0 15.8 32.9 26.5 23.4 62.3 29.2 15.5 41.8 26.5 16.5 27.4 20.7 147.2 38.6 23.5 17.0 75.3 32.6 25.5 21.6 96.2 8.1 20.3 21.4 6.5 32.2 16.5 55.6 11.1 14.5 30.0 79.4 9.1 46.3 20.1 47.1 22.6 21.5 18.1 6.6 7.0 20.7 50.8 13.0 13.8 21.6 48.8 36.3 35.5 65.2 20.6 MVK "LRBP, MK" ENSG00000110921 "Mevalonate kinase" Q03426 12 109573255-109598125 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.1" "Cell type enhanced" "Detected in all" "Early spermatids: 60.5;Horizontal cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016961, HPA044110" Approved Supported Vesicles,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Vesicles, Cytosol" "HPA016961: AB_1854220, HPA044110: " "unprognostic (3.10e-1)" "unprognostic (2.27e-2)" "unprognostic (1.85e-1)" "unprognostic (4.43e-2)" "unprognostic (3.66e-2)" "unprognostic (2.08e-2)" "unprognostic (4.30e-2)" "unprognostic (8.98e-2)" "unprognostic (1.05e-1)" "unprognostic (2.73e-2)" "unprognostic (8.23e-2)" "unprognostic (1.30e-1)" "unprognostic (6.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (3.88e-1)" "unprognostic (3.28e-1)" 7.9 29.8 12.7 6.1 13.7 8.3 14.7 16.7 15.0 14.5 9.6 11.2 13.9 7.3 10.2 45.5 6.3 5.3 9.4 11.1 13.2 32.1 69.1 11.4 6.9 36.1 15.5 10.7 10.0 11.5 11.6 5.4 38.6 12.3 8.6 7.3 13.7 7.0 12.1 33.3 9.8 5.0 15.3 6.7 11.8 28.5 15.3 4.2 15.1 8.8 9.1 9.5 20.1 24.4 30.1 25.0 29.9 13.7 11.2 27.3 14.4 9.5 21.7 30.0 32.8 31.4 33.8 17.7 7.8 11.7 48.1 36.0 31.6 50.0 13.2 19.0 18.1 9.9 15.7 53.7 31.5 11.1 13.0 27.2 42.1 48.8 13.6 12.6 20.9 19.0 18.7 17.4 13.6 34.5 12.0 34.6 22.6 14.9 32.3 10.5 22.1 37.0 67.4 40.9 25.1 18.7 19.8 58.7 14.0 11.0 59.7 21.1 14.1 13.2 14.5 12.0 12.8 13.3 20.6 28.2 16.1 29.2 16.6 1.0 6.9 4.0 12.6 6.5 11.3 9.4 7.4 12.4 8.6 14.1 10.9 8.3 1.6 11.0 4.6 7.0 7.6 6.4 12.7 13.7 16.7 15.0 11.1 13.2 36.1 15.5 38.6 15.3 15.3 24.4 6.1 12.8 12.4 6.8 8.3 4.7 5.2 39.7 4.6 12.4 13.1 11.0 5.7 11.5 25.8 14.7 18.8 33.0 7.3 10.4 21.5 15.6 60.5 5.8 2.3 7.1 9.0 4.8 5.1 18.1 15.3 6.8 9.7 5.1 1.3 14.7 6.4 32.7 15.6 62.2 5.2 7.8 10.2 3.4 2.2 42.5 8.1 4.8 7.2 3.7 10.3 10.6 10.3 4.0 15.3 13.2 3.2 7.2 4.1 5.5 16.4 52.4 13.5 12.2 6.6 4.0 8.2 33.9 16.8 12.0 8.5 47.9 6.1 44.8 11.1 4.6 MYBPC1 ssMyBP-C ENSG00000196091 "Myosin binding protein C1" Q00872 12 101568353-101686028 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 87 "skeletal muscle: 11290.5;tongue: 5207.7" "Cell type enhanced" "Detected in some" "Astrocytes: 34.6;Breast glandular cells: 102.4;Breast myoepithelial cells: 81.4;Cardiomyocytes: 64.7;Skeletal myocytes: 184.6" "Cancer enhanced" "Detected in many" "prostate cancer: 33.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "HAP1: 6.8" "Group enriched" "Detected in many" 9 "cerebellum: 39.6;olfactory bulb: 10.6" "Region enhanced" "Detected in many" "thalamus: 6.9" "HPA021004, HPA027614" Enhanced NA NA 240000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 37: Myocytes - Muscle contraction" "HPA021004: AB_1854232, HPA027614: AB_10602711" "prognostic favorable (4.76e-5)" "unprognostic (7.72e-2)" "unprognostic (1.09e-1)" "unprognostic (1.81e-2)" "unprognostic (3.33e-2)" "unprognostic (4.63e-2)" "unprognostic (8.67e-2)" "unprognostic (2.93e-1)" "unprognostic (9.98e-3)" "unprognostic (2.56e-1)" "unprognostic (2.55e-1)" "unprognostic (1.19e-2)" "unprognostic (4.10e-2)" "unprognostic (7.96e-2)" "unprognostic (6.13e-2)" "unprognostic (5.55e-3)" 1.5 0.3 55.5 0.1 66.5 0.0 63.7 60.4 71.6 1.9 36.3 4.5 0.1 0.2 1.1 94.7 0.8 0.3 1.8 50.1 59.5 0.3 0.7 0.7 0.0 52.3 64.5 0.5 1.1 0.0 0.3 0.0 55.0 83.5 0.8 0.0 48.4 0.3 11290.5 6.1 7.4 0.0 49.4 0.4 1.3 3.4 68.4 2.6 1.2 5207.7 4.0 0.3 0.7 49.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 66.5 60.4 71.6 50.1 59.5 52.3 64.5 55.0 49.4 68.4 49.9 1.3 0.0 0.0 34.6 0.3 0.0 2.2 0.0 0.0 0.0 102.4 81.4 64.7 0.0 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.0 16.5 0.1 0.1 1.2 0.0 0.0 5.3 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.2 0.0 0.8 0.3 23.7 0.6 1.2 1.8 1.0 0.0 0.0 0.0 0.5 0.5 0.1 1.6 0.4 0.0 16.3 0.3 0.1 0.0 0.0 0.0 184.6 2.7 1.4 1.4 0.0 0.0 0.0 0.7 0.0 0.3 2.9 MYCN "bHLHe37, MYCNOT, N-myc, NMYC" ENSG00000134323 "MYCN proto-oncogene, bHLH transcription factor" P04198 2 15940550-15947007 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 9.5" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 84.2;Granulosa cells: 26.4" "Cancer enriched" "Detected in many" 5 "testis cancer: 45.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 44.1;BEWO: 239.1;HMC-1: 57.3;NTERA-2: 91.3;RH-30: 63.3;SuSa: 40.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057420 Approved Nucleoplasm,Nucleoli NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli Nucleoplasm "HPA057420: AB_2683434" "unprognostic (8.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (2.07e-2)" "unprognostic (4.11e-1)" "unprognostic (2.46e-2)" "unprognostic (1.23e-2)" "unprognostic (3.03e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.09e-2)" "unprognostic (2.09e-1)" "unprognostic (1.12e-3)" "unprognostic (8.89e-2)" "unprognostic (2.47e-1)" "unprognostic (4.90e-2)" "unprognostic (1.23e-1)" 0.4 0.8 3.5 0.6 3.5 0.9 0.4 3.1 3.9 1.5 0.8 0.6 1.6 0.9 0.1 0.7 0.5 0.3 1.2 3.4 3.0 3.3 0.8 0.7 1.6 4.4 3.9 5.1 0.2 0.1 0.3 9.5 3.7 0.1 0.5 1.0 4.7 0.2 0.4 1.4 0.9 0.3 3.3 0.3 4.6 3.6 3.5 2.9 2.9 0.7 1.2 0.5 0.4 5.9 0.0 0.0 44.1 0.0 0.0 0.0 239.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 4.2 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 16.8 0.0 0.0 0.0 0.0 57.3 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.8 0.4 0.2 91.3 2.1 0.0 0.0 63.3 12.8 0.0 3.1 1.0 16.0 0.0 0.1 0.0 40.9 0.1 0.0 0.0 0.0 1.2 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.5 3.1 3.9 3.4 3.0 4.4 3.9 3.7 3.3 3.5 5.9 0.8 0.0 0.0 0.7 0.0 0.5 0.1 0.0 0.0 2.6 0.1 0.9 0.7 0.0 0.0 0.0 0.0 5.6 0.0 0.2 0.0 0.0 1.2 0.5 0.1 2.7 0.0 4.2 2.0 0.0 84.2 1.0 2.6 0.8 0.0 26.4 0.0 0.6 2.4 0.0 4.2 0.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.0 0.1 1.0 0.0 10.1 7.5 0.3 1.1 0.4 0.0 0.0 0.4 3.2 0.0 0.2 0.0 4.2 0.7 1.3 3.7 0.3 0.0 11.5 0.0 9.4 0.3 0.0 MYH11 "SMHC, SMMHC" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3322.6;seminal vesicle: 1665.5;urinary bladder: 2048.3" "Group enriched" "Detected in many" 8 "Peritubular cells: 1669.7;Sertoli cells: 624.5;Smooth muscle cells: 964.6" "Group enriched" "Detected in many" 5 "prostate cancer: 173.2;stomach cancer: 125.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;RPMI-8226: 1.4;U-698: 7.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 39.8" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 23000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB002302: AB_563902, HPA014539: AB_1234906, HPA015310: AB_1854261" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (4.18e-2)" "unprognostic (9.21e-3)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "prognostic favorable (1.10e-5)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (4.06e-2)" "unprognostic (9.53e-2)" "unprognostic (5.00e-2)" "unprognostic (5.45e-3)" 172.9 38.6 5.0 109.1 17.2 0.2 78.4 5.5 14.5 372.3 11.1 3322.6 95.4 1074.6 219.7 759.7 606.1 250.6 74.8 5.3 5.2 27.9 9.2 108.9 9.5 9.0 7.0 144.0 10.7 2.8 11.6 68.2 7.1 762.7 293.2 0.4 83.3 1665.5 41.2 68.5 487.4 1053.2 5.8 46.0 832.5 60.9 7.2 2.9 46.0 34.6 5.3 2048.3 314.2 6.3 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.2 0.2 7.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 5.0 17.2 5.5 14.5 5.3 5.2 9.0 7.0 7.1 5.8 7.2 6.3 7.6 0.0 1.8 0.0 4.4 13.3 2.1 1.7 5.7 2.7 5.3 122.3 40.5 0.0 1.9 0.0 8.4 0.3 3.4 0.4 0.0 0.2 50.2 4.7 19.5 12.8 1.2 0.8 0.8 0.4 0.3 22.2 0.0 3.4 0.0 27.3 6.4 0.1 1.1 0.0 5.2 0.5 0.0 2.2 17.3 46.2 42.9 2.8 12.4 15.9 3.7 0.3 3.1 1.5 10.7 0.4 0.2 1669.7 2.4 5.6 0.1 0.2 2.5 1.9 624.5 4.3 964.6 3.1 8.8 3.5 18.6 0.0 5.7 34.7 0.4 2.6 MYH3 "HEMHC, MYHC-EMB, MYHSE1, SMHCE" ENSG00000109063 "Myosin heavy chain 3" P11055 17 10628526-10657309 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 29.0;seminal vesicle: 18.3;skeletal muscle: 20.6" "Cell type enriched" "Detected in many" 7 "Early spermatids: 411.9" "Group enriched" "Detected in many" 4 "head and neck cancer: 3.3;prostate cancer: 4.6;testis cancer: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 26 "HSkMC: 59.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA021808 Enhanced NA NA 29000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA021808: AB_1854242" "unprognostic (1.70e-2)" "unprognostic (1.10e-3)" "unprognostic (4.19e-4)" "unprognostic (3.35e-1)" "unprognostic (7.66e-2)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.28e-1)" "unprognostic (1.67e-2)" "unprognostic (3.54e-1)" "unprognostic (7.84e-4)" "unprognostic (1.29e-1)" "unprognostic (3.24e-4)" "unprognostic (1.91e-2)" "unprognostic (6.17e-3)" "unprognostic (3.40e-2)" "unprognostic (3.49e-1)" 1.6 0.9 1.8 1.1 1.7 0.8 1.5 1.5 1.9 2.9 1.5 7.9 1.1 3.4 1.2 9.1 2.6 0.5 1.0 1.6 1.6 2.1 3.3 1.2 1.3 1.8 1.8 2.3 2.4 0.3 1.5 0.4 1.7 29.0 1.0 1.8 1.5 18.3 20.6 2.8 2.5 1.7 1.4 2.6 1.7 4.6 1.8 3.0 3.4 6.0 0.6 4.4 3.8 1.8 0.2 1.1 0.8 1.1 1.0 0.3 1.0 0.8 0.4 0.5 0.5 1.0 0.1 0.7 0.3 0.4 0.2 1.1 0.5 0.2 1.0 0.7 0.9 1.0 0.3 1.6 0.3 0.6 1.4 59.6 0.4 0.6 0.8 0.1 0.1 1.3 0.4 0.1 0.2 0.7 1.0 2.3 0.9 0.3 0.6 0.8 0.8 0.3 0.3 0.3 0.0 0.4 0.4 0.0 0.3 0.7 0.3 0.3 0.3 0.1 1.0 0.3 0.1 1.3 1.1 0.3 0.3 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.7 1.5 1.9 1.6 1.6 1.8 1.8 1.7 1.4 1.8 1.8 0.5 0.0 9.8 4.6 0.7 2.9 0.9 0.1 0.6 4.9 0.7 1.8 3.6 1.5 0.7 0.0 6.2 0.4 0.8 0.9 0.0 0.6 411.9 0.5 0.8 1.4 0.0 2.7 3.9 0.6 0.8 1.1 1.1 0.5 7.6 0.8 0.4 0.6 0.1 0.0 3.4 0.5 0.0 0.8 0.3 56.0 2.8 1.2 1.8 1.9 0.2 1.8 0.0 7.5 5.4 0.7 0.2 2.6 0.0 1.5 1.8 0.3 0.3 4.6 0.0 5.5 0.8 10.7 4.2 0.3 1.6 0.5 1.4 0.2 0.8 0.3 MYH6 ENSG00000197616 "Myosin heavy chain 6" P13533 14 23381982-23408273 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "heart muscle: 2882.7" "Cell type enriched" "Detected in some" 17 "Cardiomyocytes: 8051.1" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 23 "NTERA-2: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001239, HPA001349, CAB075723, CAB075724, CAB075725" Enhanced Uncertain "Focal adhesion sites" NA NA 25000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" "CAB075723: AB_2665728, CAB075724: AB_2665729, CAB075725: AB_2665730, HPA001239: AB_1079438, HPA001349: AB_1079437" "unprognostic (2.09e-2)" "unprognostic (8.53e-4)" "unprognostic (1.80e-2)" "unprognostic (2.99e-1)" "unprognostic (1.66e-1)" "unprognostic (2.09e-1)" "unprognostic (1.66e-1)" "unprognostic (5.73e-2)" "unprognostic (1.44e-2)" "unprognostic (5.34e-3)" "unprognostic (6.90e-2)" "unprognostic (1.42e-1)" "unprognostic (1.85e-1)" "unprognostic (1.22e-2)" 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 2882.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.9 5.8 0.0 0.0 0.5 0.1 0.9 0.0 0.0 1.9 0.0 53.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 50.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8051.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 31.7 0.0 2.7 0.1 0.0 0.0 449.6 0.0 0.0 0.0 0.3 1.1 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 60.3 0.1 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 MYH8 "MyHC-peri, MyHC-pn" ENSG00000133020 "Myosin heavy chain 8" P13535 17 10390322-10421950 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "esophagus: 15.9;lymphoid tissue: 10.7;skeletal muscle: 16.7;tongue: 10.0" "Group enriched" "Detected in some" 8 "Proximal tubular cells: 84.8;Skeletal myocytes: 52.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.7;renal cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "HSkMC: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001349, CAB016527" Enhanced Uncertain "Focal adhesion sites" NA NA 53000000 "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "Focal adhesion sites" "CAB016527: AB_2147291, HPA001349: AB_1079437" "unprognostic (5.87e-2)" "unprognostic (5.13e-3)" "unprognostic (4.12e-2)" "unprognostic (1.25e-2)" "unprognostic (2.29e-3)" "unprognostic (1.08e-1)" "unprognostic (5.02e-3)" "unprognostic (7.87e-2)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.0 16.7 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 10.7 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 3.7 0.0 0.0 0.0 0.0 7.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 84.8 0.0 0.0 0.0 52.0 0.1 0.5 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 MYMK "TMEM226, TMEM8C" ENSG00000187616 "Myomaker, myoblast fusion factor" A6NI61 9 133514586-133528612 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Myogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 32 "HSkMC: 15.2;RH-30: 7.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA051846, HPA055785" Uncertain NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA051846: AB_2681636, HPA055785: AB_2682920" "unprognostic (9.17e-3)" "unprognostic (8.63e-2)" "unprognostic (3.76e-1)" "unprognostic (1.13e-1)" "unprognostic (1.03e-1)" "unprognostic (5.37e-1)" "unprognostic (9.32e-2)" "unprognostic (1.91e-1)" 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.4 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.5 0.2 0.1 0.5 0.2 0.4 0.2 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MYO18B BK125H2.1 ENSG00000133454 "Myosin XVIIIB" Q8IUG5 22 25742144-26031045 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 120.8;skeletal muscle: 262.7;tongue: 55.6" "Group enriched" "Detected in some" 21 "Cardiomyocytes: 95.5;Early spermatids: 61.4;Late spermatids: 37.3;Skeletal myocytes: 32.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.8" "Region enhanced" "Detected in single" "thalamus: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 10.6;REH: 15.0;RH-30: 30.5;U-2 OS: 13.2;U-266/70: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA000953 Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Centrosome" "HPA000953: AB_1079440" "unprognostic (3.28e-2)" "unprognostic (1.79e-1)" "unprognostic (1.86e-2)" "unprognostic (1.23e-1)" "unprognostic (1.66e-2)" "unprognostic (1.01e-2)" "unprognostic (5.93e-4)" "unprognostic (2.46e-1)" "unprognostic (1.22e-1)" "unprognostic (7.14e-2)" "unprognostic (4.36e-3)" "unprognostic (2.96e-3)" "unprognostic (3.93e-7)" "unprognostic (1.14e-1)" "unprognostic (3.12e-1)" "unprognostic (5.06e-2)" "unprognostic (1.65e-1)" 0.2 0.1 0.3 0.1 0.1 1.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 120.8 0.1 0.3 0.1 0.0 0.1 0.1 0.3 0.8 0.0 0.1 0.0 0.2 0.0 0.3 1.0 0.0 0.0 2.7 0.0 262.7 0.5 0.0 0.0 0.2 0.0 1.5 10.2 2.3 1.9 0.1 55.6 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 5.3 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.0 4.0 0.0 0.4 1.6 0.0 0.0 0.0 15.0 30.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 13.2 0.0 0.0 9.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.1 0.3 0.3 0.8 0.3 0.2 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.4 0.0 0.2 1.2 0.0 0.0 1.8 0.0 0.0 1.7 2.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 37.3 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.7 0.9 2.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 MYOCD MYCD ENSG00000141052 Myocardin Q8IZQ8 17 12665890-12768949 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.2" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 47.3;Endometrial stromal cells: 48.5;Peritubular cells: 100.8;Sertoli cells: 26.3;Smooth muscle cells: 32.9" "Cancer enhanced" "Detected in some" "stomach cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 6.5;BJ hTERT+: 6.4;HBF TERT88: 10.4;hTEC/SVTERT24-B: 11.7;REH: 8.4;SuSa: 12.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "CAB046485, HPA071528, HPA072582" Approved Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB046485: AB_10600720, HPA071528: , HPA072582: " "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (1.90e-1)" "unprognostic (3.79e-2)" "unprognostic (5.33e-2)" "unprognostic (2.15e-4)" "unprognostic (2.71e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (4.83e-2)" "unprognostic (1.01e-4)" "unprognostic (2.88e-2)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.91e-2)" 3.2 1.0 0.4 4.3 0.7 0.0 1.2 0.3 0.8 9.4 1.6 24.2 2.6 13.0 2.4 13.1 8.5 4.6 14.2 0.4 0.4 0.7 0.2 2.7 0.1 0.5 0.5 4.4 0.3 0.1 0.2 3.4 0.8 8.8 4.9 0.0 0.2 20.7 0.5 1.3 5.1 15.8 0.5 0.6 6.1 2.1 0.8 0.1 0.7 0.8 0.1 17.2 4.4 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.5 6.4 2.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.8 0.4 0.4 0.5 0.5 0.8 0.5 0.8 0.4 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 47.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.0 48.5 1.2 7.8 0.0 1.2 0.2 0.1 3.6 0.0 1.0 0.0 8.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 1.0 0.5 0.6 0.2 0.0 9.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 100.8 0.0 0.1 0.0 0.1 0.0 0.0 26.3 0.2 32.9 0.3 0.8 0.1 0.9 0.5 0.4 6.0 0.0 0.1 MYRF "C11orf9, MRF, Ndt80, pqn-47" ENSG00000124920 "Myelin regulatory factor" Q9Y2G1 11 61752636-61788518 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 168.0;stomach 1: 88.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1;Cholangiocytes: 60.1;Gastric mucus-secreting cells: 130.0;Oligodendrocytes: 255.8;Pancreatic endocrine cells: 70.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 38.8;CACO-2: 63.6;CAPAN-2: 34.0;EFO-21: 48.6;Hep G2: 21.8;OE19: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018310 Approved Nucleoplasm,Cytosol NA NA 1400000 "Cluster 70: Brain - Nervous system development" "Cluster 39: CACO-2 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "HPA018310: AB_1845534" "unprognostic (3.51e-2)" "unprognostic (3.34e-1)" "unprognostic (1.56e-1)" "unprognostic (5.39e-2)" "unprognostic (1.54e-1)" "unprognostic (3.65e-2)" "unprognostic (1.34e-1)" "unprognostic (9.34e-3)" "unprognostic (2.44e-1)" "unprognostic (1.27e-1)" "unprognostic (1.01e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (2.01e-4)" "unprognostic (8.91e-3)" "unprognostic (1.11e-1)" "unprognostic (2.67e-1)" "unprognostic (6.73e-2)" 15.4 0.6 31.3 1.1 99.0 0.3 0.4 67.9 67.5 2.2 0.0 3.8 11.4 13.1 0.1 2.4 15.4 17.3 2.4 36.9 48.8 12.0 16.9 22.3 0.1 101.7 89.4 17.6 31.6 0.0 0.4 1.1 84.9 0.7 1.1 0.4 0.6 0.3 0.1 0.5 10.8 1.9 43.5 0.5 88.3 3.1 85.7 0.0 0.3 0.0 0.1 0.5 0.6 168.0 3.1 38.8 4.7 1.5 0.0 0.0 0.2 0.2 0.1 0.9 0.8 63.6 34.0 0.9 48.6 0.0 1.2 0.3 1.3 0.0 0.9 0.1 0.6 0.2 0.7 21.8 18.9 0.0 0.4 0.3 0.0 0.6 0.0 10.9 0.1 1.6 11.7 0.3 0.2 0.5 0.0 0.9 1.6 37.2 4.8 0.0 0.1 1.9 6.5 0.0 0.1 0.9 0.0 0.4 0.3 10.6 0.6 0.4 1.4 0.4 19.5 0.0 0.6 0.2 0.1 0.3 0.1 2.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.3 99.0 67.9 67.5 36.9 48.8 101.7 89.4 84.9 43.5 85.7 168.0 0.1 48.1 5.1 2.3 0.6 0.1 0.1 0.2 0.0 0.5 0.8 0.8 1.3 60.1 3.4 3.7 0.0 0.4 1.6 6.4 0.0 31.7 0.2 1.4 3.2 0.6 1.2 0.0 0.9 36.7 0.3 5.6 130.0 4.1 0.0 4.4 0.7 6.0 0.9 0.0 1.1 4.5 6.1 0.0 0.6 1.2 5.9 0.8 3.6 0.0 1.0 3.5 0.0 5.5 255.8 70.5 13.0 3.8 0.4 0.2 12.8 2.2 1.3 0.3 0.0 0.2 1.2 1.4 3.7 0.8 0.0 0.8 0.7 0.3 7.7 3.1 NAA10 "ARD1, ARD1A, DXS707, TE2" ENSG00000102030 "N-alpha-acetyltransferase 10, NatA catalytic subunit" P41227 X 153929225-153935080 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006269, HPA030711" Supported Supported Nucleoli,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoli "CAB006269: AB_425759, HPA030711: AB_2673579" "unprognostic (7.57e-2)" "unprognostic (1.40e-2)" "unprognostic (1.81e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (1.94e-2)" "unprognostic (4.52e-3)" "unprognostic (1.22e-1)" "unprognostic (1.68e-1)" "unprognostic (1.04e-1)" "unprognostic (9.01e-2)" "unprognostic (9.63e-2)" "prognostic unfavorable (3.29e-8)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-2)" "unprognostic (7.48e-3)" 38.4 39.5 19.6 17.2 20.1 13.2 34.6 20.4 27.2 26.5 19.2 34.1 15.3 32.3 15.1 40.5 24.4 10.3 56.3 20.0 21.8 34.1 35.9 26.0 19.7 20.8 20.3 23.8 45.8 13.7 22.5 12.5 20.8 27.6 10.2 7.3 25.3 12.2 98.4 30.9 24.9 18.1 20.4 28.8 35.9 9.1 21.2 10.2 21.7 24.9 15.3 35.9 26.8 20.4 133.4 136.0 25.8 83.0 36.7 36.9 71.2 46.3 28.6 63.8 57.0 88.5 41.0 102.0 147.6 38.7 79.2 63.0 57.9 56.8 23.9 42.1 255.2 36.8 85.8 91.3 49.1 71.4 76.8 28.8 62.2 57.9 59.1 30.7 72.0 39.2 75.1 41.5 41.6 172.8 115.0 106.4 42.9 124.4 189.0 90.1 65.7 111.5 47.7 59.7 54.0 65.7 18.7 71.0 113.7 23.9 38.4 58.8 41.1 25.6 88.5 89.5 142.0 86.3 107.2 196.0 34.7 91.0 75.5 35.3 53.1 81.3 60.0 65.3 78.1 75.2 63.4 65.6 69.4 77.7 37.4 56.7 49.8 64.7 76.0 75.9 102.9 70.6 19.6 20.1 20.4 27.2 20.0 21.8 20.8 20.3 20.8 20.4 21.2 20.4 126.9 9.6 30.2 27.1 76.0 70.1 66.1 90.6 68.3 29.5 82.6 113.8 45.1 47.1 52.8 38.6 12.5 125.9 77.0 94.5 95.9 121.1 2.9 46.0 60.7 98.7 58.1 78.9 18.6 149.9 179.0 57.3 76.5 43.4 67.9 64.2 77.8 78.7 123.1 37.0 14.6 92.2 54.9 66.5 96.0 12.5 46.6 66.4 119.2 9.4 84.8 37.9 85.5 14.1 19.1 144.6 75.2 46.6 104.3 136.9 91.5 197.0 40.2 30.4 65.7 56.6 98.3 7.6 33.1 120.7 90.5 108.8 74.8 97.7 110.3 85.9 NACC1 "BEND8, BTBD14B, BTBD30, NAC-1, NAC1" ENSG00000160877 "Nucleus accumbens associated 1" Q96RE7 19 13116862-13141147 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021238, HPA062245, CAB069927" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "CAB069927: AB_1082966, HPA021238: AB_1845475, HPA062245: AB_2684724" "unprognostic (2.19e-1)" "unprognostic (9.20e-3)" "unprognostic (2.67e-2)" "unprognostic (2.84e-2)" "unprognostic (2.62e-1)" "unprognostic (7.75e-2)" "unprognostic (8.46e-3)" "unprognostic (1.10e-1)" "unprognostic (1.93e-1)" "unprognostic (8.46e-2)" "unprognostic (2.40e-2)" "unprognostic (3.04e-2)" "unprognostic (7.35e-2)" "unprognostic (2.80e-2)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (9.74e-2)" 12.6 19.5 31.0 14.6 19.2 8.8 10.3 7.1 26.6 9.7 0.0 17.3 13.3 18.4 7.9 27.6 11.9 6.4 20.9 25.7 7.4 14.8 20.5 16.7 12.1 13.4 15.9 7.7 12.2 10.7 14.8 12.4 15.1 14.6 6.6 3.7 15.8 11.2 24.2 17.4 16.0 7.7 8.9 15.9 16.0 17.0 20.6 11.3 14.0 7.9 8.8 15.0 12.6 16.4 98.8 110.0 28.0 59.6 15.0 17.7 74.9 47.4 34.2 42.4 32.4 114.8 40.4 50.9 104.1 39.8 37.3 49.0 34.8 80.7 16.2 89.1 52.5 32.4 87.9 84.7 35.5 52.0 82.3 28.8 28.0 46.1 24.7 36.5 50.2 46.4 72.5 19.8 22.9 206.1 82.9 39.6 123.6 28.9 101.7 47.8 32.9 49.5 28.2 101.1 58.2 37.7 49.6 64.9 39.1 29.8 59.3 46.4 76.7 94.6 58.8 67.2 87.0 53.4 88.1 42.4 99.7 52.8 58.9 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.1 31.0 19.2 7.1 26.6 25.7 7.4 13.4 15.9 15.1 8.9 20.6 16.4 4.9 0.0 1.7 6.2 5.6 12.1 7.5 11.8 2.8 16.6 11.5 7.5 2.1 12.8 8.5 16.5 2.1 19.0 12.9 22.7 7.9 12.3 2.3 10.9 8.9 8.1 4.9 12.2 7.2 8.8 20.0 5.2 10.7 17.6 10.2 13.3 8.6 18.0 21.1 26.9 5.9 16.2 14.2 9.6 9.6 2.0 4.4 8.8 5.4 3.7 10.5 12.0 10.3 5.5 5.4 21.7 11.1 9.4 5.6 16.5 14.0 15.0 5.9 7.7 6.6 7.5 7.0 11.1 15.6 8.4 13.9 27.1 7.9 15.2 15.4 17.2 NALCN "bA430M15.1, CanIon, VGCNL1" ENSG00000102452 "Sodium leak channel, non-selective" Q8IZF0 13 101053776-101416508 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.1" "Group enriched" "Detected in some" 10 "Astrocytes: 125.4;Excitatory neurons: 265.8;Inhibitory neurons: 277.4;Oligodendrocyte precursor cells: 324.7;Oligodendrocytes: 477.4" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.6" "Cell line enhanced" "Detected in many" "HaCaT: 14.2;HHSteC: 14.4;hTERT-RPE1: 11.0;TIME: 19.8;U-87 MG: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031889, HPA031890, HPA031958" Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA031889: AB_10669638, HPA031890: AB_10696056, HPA031958: AB_10601039" "unprognostic (4.66e-1)" "unprognostic (6.55e-3)" "unprognostic (1.86e-3)" "unprognostic (6.78e-3)" "unprognostic (1.16e-1)" "unprognostic (1.37e-3)" "unprognostic (8.11e-2)" "unprognostic (2.60e-1)" "unprognostic (7.72e-2)" "unprognostic (5.92e-2)" "unprognostic (1.25e-1)" "unprognostic (2.18e-1)" "unprognostic (1.58e-5)" "unprognostic (1.77e-3)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" 0.5 4.3 7.5 0.4 9.8 0.6 2.7 6.4 10.3 1.5 0.0 0.4 0.6 0.5 1.5 0.2 1.0 2.3 3.3 8.6 10.2 0.3 1.2 1.1 0.3 8.2 5.8 2.8 1.3 2.9 6.8 3.0 7.0 0.3 0.6 6.1 0.8 1.0 0.3 0.5 0.5 0.5 6.8 0.4 0.7 0.6 8.3 0.0 2.4 0.2 0.1 0.5 0.2 13.1 0.1 7.8 1.4 0.2 0.7 0.3 0.1 0.8 0.8 1.8 0.4 0.2 8.9 0.0 0.3 3.6 0.8 14.2 0.0 2.2 5.5 0.0 1.2 0.4 3.8 0.1 14.4 0.2 0.3 0.4 0.5 1.7 4.6 11.0 8.2 0.1 0.1 0.4 5.9 0.0 0.1 0.0 0.4 1.3 1.8 0.0 0.0 0.0 4.6 1.9 1.2 0.6 0.1 0.0 0.8 0.9 0.2 0.1 19.8 0.4 0.1 0.3 1.8 0.1 0.1 0.1 11.4 0.1 0.3 2.6 0.1 0.2 0.3 0.0 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 0.5 0.2 0.1 0.2 0.1 0.1 7.5 9.8 6.4 10.3 8.6 10.2 8.2 5.8 7.0 6.8 8.3 13.1 0.1 0.0 0.0 125.4 0.0 0.3 0.0 0.3 0.6 15.4 3.5 4.6 6.2 0.0 0.1 0.0 6.2 1.0 0.0 0.0 0.0 0.8 4.5 0.1 0.2 0.6 0.0 0.0 265.8 0.2 0.2 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 26.9 277.4 0.0 0.0 0.0 0.0 0.9 0.3 0.1 0.0 23.4 0.0 2.0 0.0 324.7 477.4 0.3 0.0 1.9 0.0 0.0 0.0 0.1 0.0 2.6 0.0 3.6 0.5 0.2 0.8 0.0 0.1 0.5 0.0 0.1 0.0 0.0 NANS SAS ENSG00000095380 "N-acetylneuraminate synthase" Q9NR45 9 98056732-98083077 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 362.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019223 Approved Enhanced Nucleoplasm No No 410000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA019223: AB_1854298" "unprognostic (2.95e-1)" "unprognostic (5.10e-3)" "unprognostic (2.24e-2)" "prognostic favorable (1.71e-4)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.42e-4)" "unprognostic (2.08e-1)" "unprognostic (7.98e-2)" "unprognostic (2.28e-1)" "unprognostic (1.54e-2)" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (1.64e-1)" "unprognostic (7.36e-2)" "unprognostic (3.62e-3)" "unprognostic (1.79e-1)" 39.4 28.9 16.2 49.3 15.0 67.8 36.5 13.8 18.2 49.9 29.8 133.5 52.2 28.5 33.5 51.4 29.4 34.2 46.3 15.1 17.0 32.8 67.0 45.9 59.5 16.2 17.2 26.2 67.6 20.4 42.5 31.7 18.4 106.4 129.2 8.3 120.0 19.7 34.2 29.2 47.8 29.0 15.1 53.3 76.1 27.2 17.2 18.8 27.3 17.4 60.5 47.5 41.5 17.2 387.9 111.8 32.5 94.5 64.0 68.8 70.5 120.9 93.7 96.3 78.3 134.8 53.6 118.1 57.2 133.3 101.9 134.1 61.0 103.6 80.0 95.7 91.0 70.3 128.4 271.9 176.3 80.3 55.3 58.4 69.1 102.9 116.4 111.8 104.3 57.9 129.9 119.8 71.2 265.0 54.1 114.9 56.2 277.5 143.3 103.4 89.0 121.5 78.2 116.6 65.7 34.4 77.8 414.4 107.2 35.8 137.6 85.3 274.2 74.8 72.5 193.4 125.8 110.7 99.3 45.7 88.4 95.9 59.6 30.9 190.9 29.5 34.9 237.6 53.4 55.6 45.5 36.8 194.7 54.9 48.8 33.7 77.4 38.9 217.0 178.8 58.3 91.4 16.2 15.0 13.8 18.2 15.1 17.0 16.2 17.2 18.4 15.1 17.2 17.2 46.7 28.9 54.9 3.6 57.0 70.1 134.0 183.0 30.7 11.4 61.6 45.5 25.3 42.9 206.3 22.0 18.8 86.7 50.2 234.3 70.5 49.4 42.8 63.4 37.9 63.4 64.9 18.7 6.7 100.7 159.2 50.6 99.4 55.8 43.8 29.5 34.2 33.6 160.0 10.1 7.2 362.7 95.6 67.7 107.6 71.5 32.3 89.8 129.9 6.5 53.1 14.1 14.4 2.0 3.1 70.9 181.0 26.4 141.1 213.6 66.5 68.3 204.5 8.0 13.1 32.9 91.3 10.5 21.9 42.0 61.7 150.8 50.6 44.6 260.1 223.3 NBAS NAG ENSG00000151779 "NBAS subunit of NRZ tethering complex" A2RRP1 2 15166914-15561334 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 217.8;Inhibitory neurons: 187.9;Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 159.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036817 Approved Approved "Nuclear membrane,Nucleoli,Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nuclear membrane, Nucleoli" "HPA036817: AB_10670925" "unprognostic (1.72e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (2.36e-1)" "unprognostic (1.32e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (3.80e-2)" "unprognostic (4.16e-2)" "unprognostic (1.33e-1)" "unprognostic (1.55e-1)" "unprognostic (1.53e-2)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-1)" "prognostic unfavorable (5.84e-5)" 16.8 21.0 37.4 7.2 38.8 16.1 15.9 37.7 42.7 18.8 35.7 22.7 8.2 18.4 13.7 17.2 18.8 8.1 38.3 37.2 36.3 19.9 21.6 15.8 9.4 37.0 35.2 22.5 34.4 16.3 29.6 10.1 38.7 19.0 10.5 13.4 15.4 10.4 30.5 21.8 20.1 11.8 34.4 21.1 24.5 41.2 37.2 14.5 17.4 17.7 9.1 19.7 16.5 38.1 10.5 13.7 14.8 10.7 37.8 41.5 15.2 19.1 20.8 14.5 14.6 13.8 15.0 13.4 4.3 29.3 15.1 12.5 16.5 23.9 17.2 13.5 10.4 51.3 11.5 38.8 38.8 13.4 25.1 27.3 18.9 19.2 32.8 30.2 30.4 18.7 40.6 15.0 22.4 13.0 11.2 30.1 12.8 17.1 12.8 11.7 26.0 16.2 30.5 14.0 8.7 14.2 16.2 13.4 25.2 18.3 9.4 12.0 26.6 18.5 11.2 13.5 13.9 22.1 20.3 18.7 33.1 15.5 16.8 1.5 4.4 2.5 5.7 3.1 6.7 4.1 4.2 7.3 4.0 3.4 4.2 4.3 0.8 7.2 7.5 4.5 5.3 2.9 37.4 38.8 37.7 42.7 37.2 36.3 37.0 35.2 38.7 34.4 37.2 38.1 16.1 19.2 13.8 96.6 15.1 7.4 9.3 11.9 12.0 17.3 11.7 9.4 32.3 17.2 13.8 18.4 29.2 11.5 15.1 9.4 0.0 11.1 39.3 22.2 21.3 14.6 7.3 38.7 217.8 14.0 13.1 13.4 20.9 14.8 38.6 30.2 8.9 9.1 9.0 13.5 187.9 14.8 10.2 6.9 8.0 61.9 11.5 11.6 5.4 106.8 18.4 12.5 9.2 159.3 159.2 8.6 9.5 16.6 27.2 9.2 39.3 8.5 26.0 25.5 0.0 24.7 16.3 33.7 22.4 12.9 11.2 10.4 19.9 70.0 12.5 7.6 NCAPD2 "CAP-D2, CNAP1, hCAP-D2, KIAA0159" ENSG00000010292 "Non-SMC condensin I complex subunit D2" Q15021 12 6493356-6531955 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 76.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.0;Late spermatids: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012423, HPA036947, HPA037363" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes 34000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Nucleoli" "CAB012423: , HPA036947: AB_10671367, HPA037363: AB_10672483" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-2)" "unprognostic (1.03e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (1.79e-8)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (5.00e-2)" "unprognostic (5.41e-3)" "unprognostic (4.53e-1)" "prognostic unfavorable (1.13e-7)" "unprognostic (4.80e-3)" "unprognostic (1.18e-1)" "unprognostic (4.53e-1)" "unprognostic (8.75e-2)" 8.3 7.4 7.3 21.5 11.4 35.5 10.9 9.9 8.3 10.2 7.4 17.9 17.0 10.7 10.6 15.9 11.2 9.8 7.6 7.2 8.0 7.4 4.8 10.6 38.1 11.0 10.0 8.0 7.7 11.3 5.5 17.5 11.7 9.4 20.4 11.1 11.8 10.2 7.9 21.9 16.0 13.4 8.4 16.1 12.1 18.2 10.2 76.8 11.3 10.2 44.8 10.1 9.3 13.9 125.3 99.3 134.6 97.9 29.9 28.4 159.2 76.1 69.8 138.3 109.1 123.5 150.8 135.8 24.2 63.2 126.7 128.6 188.0 105.4 194.1 214.1 92.8 112.2 113.8 79.4 12.5 145.0 96.5 20.5 31.6 112.4 107.8 61.9 89.9 94.0 71.0 63.4 104.7 79.6 162.2 73.8 207.5 129.9 78.2 153.7 260.6 77.7 39.5 64.1 54.0 61.9 121.5 64.9 44.3 189.1 27.0 101.7 51.0 94.1 149.6 60.8 168.4 45.3 51.7 181.0 55.7 92.2 126.1 11.0 1.7 3.7 7.1 2.8 5.3 5.1 6.4 7.3 3.4 3.5 7.3 7.3 1.4 8.1 2.2 4.1 8.3 3.9 7.3 11.4 9.9 8.3 7.2 8.0 11.0 10.0 11.7 8.4 10.2 13.9 4.3 6.4 7.4 4.9 11.0 3.6 3.8 4.4 17.1 3.7 4.7 6.9 4.1 5.7 3.4 1.8 8.4 13.5 8.9 7.3 0.0 4.5 18.3 5.3 6.3 5.4 1.2 48.0 5.6 3.7 17.8 6.4 7.1 5.8 3.8 20.0 8.9 3.3 10.1 5.0 5.0 9.9 6.1 16.4 4.4 34.3 5.9 10.8 0.0 2.8 9.5 11.8 15.5 2.5 17.8 5.3 4.6 6.0 22.6 4.1 6.0 2.4 4.2 8.4 0.0 4.2 5.2 21.3 13.7 19.3 3.4 6.3 12.0 6.1 14.7 4.1 NCAPD3 "CAP-D3, FLJ42888, hCAP-D3, hcp-6, hHCP-6, KIAA0056" ENSG00000151503 "Non-SMC condensin II complex subunit D3" P42695 11 134150113-134225454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "prostate: 58.5" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 8 "prostate cancer: 50.8" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040286 Supported Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA040286: AB_2676918" "unprognostic (4.27e-2)" "unprognostic (6.05e-2)" "unprognostic (7.78e-3)" "unprognostic (8.22e-3)" "unprognostic (2.79e-1)" "unprognostic (4.29e-2)" "unprognostic (2.15e-3)" "unprognostic (2.56e-1)" "unprognostic (4.32e-2)" "unprognostic (4.75e-1)" "unprognostic (2.79e-3)" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.93e-2)" "unprognostic (3.35e-2)" "unprognostic (3.94e-1)" "unprognostic (3.48e-1)" 4.7 5.5 1.9 3.1 2.0 10.0 4.9 4.0 3.8 4.2 2.3 4.4 3.5 4.0 3.3 7.1 3.8 2.6 5.0 3.1 1.6 3.6 8.8 4.9 4.2 2.0 1.1 3.4 4.5 1.9 7.0 3.1 1.1 58.5 1.5 4.5 5.7 0.9 3.7 9.0 5.4 1.3 0.9 6.2 5.1 9.5 1.6 3.1 6.0 0.9 1.7 3.7 5.2 3.0 5.5 1.9 12.3 25.3 1.8 1.3 10.6 11.5 1.9 3.5 4.0 5.6 3.4 6.1 11.1 3.5 9.8 6.1 3.5 5.2 4.4 9.2 21.7 26.6 5.1 8.5 2.3 13.1 15.4 1.7 1.1 5.1 2.0 3.6 2.6 11.6 7.1 4.7 4.2 6.0 10.9 15.1 8.6 5.5 13.8 2.9 13.7 8.5 4.1 3.2 22.1 13.4 9.1 5.9 1.7 10.0 9.7 6.9 1.7 11.8 5.7 11.8 9.9 4.5 4.5 5.5 8.3 16.4 15.2 1.6 3.3 1.6 5.7 2.7 2.2 2.3 3.7 3.8 2.5 5.2 5.5 5.8 1.6 1.7 2.2 8.0 6.5 1.9 1.9 2.0 4.0 3.8 3.1 1.6 2.0 1.1 1.1 0.9 1.6 3.0 7.7 3.2 8.1 8.5 12.1 9.2 4.4 6.0 8.0 20.2 9.9 8.6 6.7 2.8 7.0 12.9 10.4 13.0 13.2 5.4 0.0 2.7 7.2 7.8 12.8 5.6 7.8 32.8 19.7 2.6 9.9 7.5 7.7 9.0 2.5 19.6 5.7 9.7 8.8 11.8 16.7 7.2 10.2 6.4 8.7 10.4 4.7 10.9 1.8 15.0 17.1 9.0 17.5 11.1 16.0 2.8 1.6 4.1 22.9 8.8 3.2 3.6 4.9 20.9 0.0 9.5 9.2 21.5 14.4 10.7 9.1 4.5 14.2 11.3 11.6 3.4 NCAPH "BRRN1, CAP-H, hCAP-H" ENSG00000121152 "Non-SMC condensin I complex subunit H" Q15003 2 96335766-96377091 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.2;lymphoid tissue: 37.4;testis: 35.4" "Cell type enhanced" "Detected in many" "Plasma cells: 26.3;Spermatocytes: 89.3;Spermatogonia: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 3.8;T-cells: 6.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA002647, HPA003008" Enhanced Supported Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoplasm "HPA002647: AB_1078300, HPA003008: AB_1078301" "unprognostic (5.52e-2)" "unprognostic (7.37e-2)" "unprognostic (2.93e-2)" "unprognostic (2.85e-3)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "prognostic unfavorable (9.53e-6)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.50e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-2)" "unprognostic (0.00e+0)" "unprognostic (3.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.14e-1)" "unprognostic (2.30e-2)" 1.2 0.7 0.3 9.9 0.4 35.2 1.8 0.9 0.9 1.3 0.1 7.7 5.6 0.9 0.2 6.3 0.5 1.6 0.4 0.3 0.2 0.4 1.0 1.1 20.3 0.1 0.0 0.3 0.3 0.5 0.2 5.2 0.3 0.4 9.3 1.8 1.5 0.2 0.3 4.7 6.2 2.8 0.0 3.7 3.6 35.4 0.1 37.4 0.4 0.1 22.0 2.6 2.0 0.3 134.1 52.0 115.1 60.6 3.9 6.1 80.8 58.7 40.3 115.1 118.4 93.5 71.5 121.0 41.8 26.6 106.2 57.2 100.2 39.6 117.2 110.0 63.4 123.7 49.3 74.5 0.7 112.2 101.3 1.8 4.2 89.1 35.9 10.2 46.6 89.7 89.5 88.8 53.0 59.5 183.8 104.2 85.9 57.6 56.6 133.4 106.7 95.5 23.6 49.6 71.2 52.3 34.8 46.5 19.9 42.4 36.6 80.0 24.1 83.5 126.3 76.9 101.9 44.4 70.1 134.0 33.7 111.5 95.3 3.8 0.0 0.2 0.8 0.9 0.1 0.9 1.2 1.0 0.4 0.9 0.0 0.4 0.3 0.1 0.0 0.0 6.2 0.5 0.3 0.4 0.9 0.9 0.3 0.2 0.1 0.0 0.3 0.0 0.1 0.3 4.9 0.0 0.0 0.0 3.5 0.6 0.7 1.9 1.2 0.4 1.0 0.8 0.5 0.0 1.6 0.0 8.4 9.4 2.0 2.1 0.0 0.5 5.9 1.7 0.9 1.8 0.0 16.4 0.4 0.0 16.3 1.8 4.1 1.2 1.3 5.5 1.4 0.4 8.5 0.0 0.3 2.8 0.0 3.8 3.7 4.9 0.9 2.2 1.8 0.0 0.2 8.5 0.0 0.5 1.0 0.2 0.1 0.4 26.3 0.7 0.4 0.0 1.6 2.3 0.0 0.2 3.5 89.3 29.4 8.8 0.9 1.9 5.1 0.6 5.7 1.1 NDE1 "FLJ20101, NDE, nudE" ENSG00000072864 "NudE neurodevelopment protein 1" Q9NXR1 16 15643267-15734691 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein" Lissencephaly "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 21.8;monocytes: 11.7;NK-cells: 8.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024075 Approved NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA024075: AB_1854336" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (3.26e-1)" "unprognostic (1.47e-1)" "unprognostic (3.84e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.43e-2)" "unprognostic (1.59e-1)" "unprognostic (4.55e-2)" "unprognostic (3.70e-3)" "unprognostic (1.16e-1)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.29e-1)" "unprognostic (3.28e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" 9.2 5.8 12.1 13.0 23.6 25.6 9.4 22.5 15.6 14.6 6.9 25.0 7.5 11.6 2.6 17.7 11.1 9.8 10.6 11.2 16.1 6.3 4.2 11.1 20.4 30.0 24.5 7.5 4.0 4.0 3.1 10.0 26.5 14.2 7.3 2.0 12.2 5.1 7.3 27.6 12.9 10.7 17.0 12.5 10.1 11.1 21.3 23.4 6.3 7.9 20.9 15.3 19.8 43.2 37.0 33.0 34.2 39.9 11.4 18.6 10.4 15.4 21.0 30.4 34.5 18.3 58.3 21.9 24.0 23.2 16.7 34.5 25.3 47.3 20.8 33.7 16.0 24.6 35.3 51.7 16.3 33.3 37.2 6.6 28.9 28.8 52.0 16.9 40.6 27.9 20.5 80.5 26.6 43.9 43.0 30.5 30.5 26.5 14.3 64.8 32.3 34.8 11.6 24.1 17.0 21.0 27.5 40.7 27.6 25.9 42.8 34.3 12.5 26.9 17.6 43.2 36.1 17.4 13.1 38.1 27.5 43.0 55.0 5.1 4.7 15.0 3.0 3.8 1.7 3.3 3.0 1.3 3.4 1.9 1.8 2.0 21.8 8.5 11.7 3.1 3.3 3.9 12.1 23.6 22.5 15.6 11.2 16.1 30.0 24.5 26.5 17.0 21.3 43.2 11.7 3.2 4.4 11.1 36.1 26.0 32.7 19.0 24.5 7.0 9.5 10.4 2.0 4.3 8.9 5.5 6.2 3.9 25.0 9.6 0.0 4.5 46.9 17.1 23.1 11.6 4.2 49.0 2.1 5.3 5.3 11.8 19.4 15.0 10.8 15.5 8.6 1.7 10.1 3.3 2.4 7.4 2.0 15.8 11.0 58.5 15.8 19.3 12.4 22.5 53.0 7.4 50.4 9.5 105.5 7.1 4.2 6.0 16.6 26.3 4.6 1.9 13.3 6.5 6.6 6.9 9.5 13.8 10.0 18.8 30.7 2.5 28.3 9.8 10.2 21.6 NDP "EVR2, norrin" ENSG00000124479 "Norrin cystine knot growth factor NDP" Q00604 X 43948776-43973395 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision, Wnt signaling pathway" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;ovary: 46.2" "Group enriched" "Detected in some" 4 "Granulosa cells: 181.3;Muller glia cells: 105.5" "Cancer enriched" "Detected in many" 5 "glioma: 25.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "U-87 MG: 72.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003095 Supported Nucleoplasm,Nucleoli,Vesicles "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA003095: AB_1079457" "unprognostic (1.12e-1)" "unprognostic (7.12e-2)" "unprognostic (2.27e-2)" "unprognostic (2.55e-3)" "unprognostic (6.84e-3)" "unprognostic (1.51e-1)" "unprognostic (9.09e-2)" "unprognostic (2.29e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.47e-1)" "unprognostic (1.13e-1)" "unprognostic (2.87e-3)" 0.5 0.0 31.5 0.0 33.4 0.0 3.3 30.9 35.8 20.9 22.4 0.2 0.1 15.4 22.0 0.0 20.8 0.4 0.3 31.5 29.6 0.1 0.0 0.0 0.2 30.1 33.2 46.2 0.0 0.2 0.1 4.0 31.6 7.1 0.2 19.2 0.1 13.1 0.0 0.6 0.2 11.4 32.4 0.1 0.3 1.0 34.2 0.0 0.2 0.0 0.2 0.5 2.3 32.4 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 1.5 0.0 0.0 0.1 1.9 0.0 0.0 0.0 1.8 0.0 4.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 2.2 0.0 0.0 0.0 72.9 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 33.4 30.9 35.8 31.5 29.6 30.1 33.2 31.6 32.4 34.2 32.4 0.0 0.0 0.0 29.0 0.0 0.1 0.0 1.2 0.0 0.6 1.3 0.1 0.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 2.0 0.0 9.1 17.7 0.2 0.0 0.0 4.2 0.0 0.3 0.9 0.0 17.0 0.0 181.3 0.0 0.0 0.1 0.0 0.8 0.0 2.0 0.0 0.0 0.7 13.4 0.6 0.0 0.0 0.0 105.5 0.0 1.5 9.5 1.2 0.0 9.8 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 5.4 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 NDUFB11 "ESSS, Np15, NP17.3" ENSG00000147123 "NADH:ubiquinone oxidoreductase subunit B11" Q9NX14 X 47142216-47145038 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 717.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030367 Supported Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA030367: AB_10603882" "unprognostic (2.20e-1)" "unprognostic (6.77e-3)" "unprognostic (1.39e-1)" "unprognostic (1.33e-1)" "unprognostic (9.80e-2)" "unprognostic (8.84e-2)" "unprognostic (3.31e-2)" "unprognostic (2.05e-1)" "unprognostic (5.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (2.19e-1)" "unprognostic (6.58e-2)" "unprognostic (3.27e-1)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (8.46e-3)" 71.1 133.8 136.0 73.2 141.2 133.2 89.8 147.7 170.6 74.6 158.5 112.5 96.7 54.4 104.6 95.2 84.1 46.2 251.4 140.3 142.3 108.9 164.4 62.2 90.3 144.7 139.0 58.5 158.2 122.9 92.7 62.4 142.0 73.9 98.2 59.2 128.2 79.2 717.0 76.1 96.1 72.2 138.3 74.5 97.8 26.8 146.3 97.8 95.6 378.4 106.3 68.0 66.5 139.3 173.5 297.9 198.7 242.4 173.6 166.1 221.1 125.2 180.5 231.5 224.4 292.6 224.2 218.5 101.8 163.4 222.3 216.2 267.0 157.3 162.0 212.4 663.1 129.5 371.2 271.3 184.7 203.2 188.2 176.9 140.0 191.2 126.8 137.8 193.9 286.8 158.6 282.6 139.3 437.2 269.1 622.5 308.5 219.2 517.2 259.7 210.9 513.6 254.0 210.1 391.2 283.1 231.9 289.2 198.8 259.8 418.2 279.7 130.3 152.7 190.5 239.1 149.0 244.0 270.0 258.5 155.0 138.4 204.2 255.4 410.3 188.6 294.2 306.5 362.1 541.7 408.9 342.6 491.6 470.0 454.3 359.3 84.9 279.7 233.8 636.5 476.3 626.1 136.0 141.2 147.7 170.6 140.3 142.3 144.7 139.0 142.0 138.3 146.3 139.3 154.0 105.8 132.5 16.6 270.9 259.5 252.1 514.5 267.5 89.2 343.7 520.1 236.6 265.9 284.7 290.6 37.5 456.9 227.6 400.0 583.0 314.9 5.2 193.4 229.7 165.6 330.7 246.3 10.2 369.1 429.2 192.1 200.8 267.1 194.1 219.2 203.8 657.2 391.0 55.5 16.7 495.1 333.7 321.7 290.9 16.3 181.7 229.1 265.1 12.2 336.9 238.9 183.4 14.1 25.3 291.8 391.2 176.4 445.1 258.6 360.1 756.8 180.9 109.8 164.3 157.6 248.9 16.8 36.9 358.0 290.5 450.9 228.9 342.6 447.4 334.9 NECTIN1 "CD111, CLPED1, ED4, HIgR, HVEC, OFC7, PRR, PRR1, PVRL1, PVRR1, SK-12" ENSG00000110400 "Nectin cell adhesion molecule 1" Q15223 11 119623408-119729200 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 128.8;skin 1: 134.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 12.1;Breast myoepithelial cells: 27.3;Exocrine glandular cells: 12.3;Granulosa cells: 68.7;Pancreatic endocrine cells: 15.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 229.2;hTCEpi: 139.2;RT4: 157.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016135, HPA026846" Approved "Secreted in other tissues" NA NA 180000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "CAB016135: AB_626865, HPA026846: AB_1846226" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (3.87e-2)" "unprognostic (1.26e-1)" "unprognostic (3.20e-2)" "unprognostic (2.25e-3)" "unprognostic (2.03e-1)" "unprognostic (3.76e-2)" "unprognostic (3.42e-1)" "unprognostic (3.58e-2)" "unprognostic (3.28e-1)" "unprognostic (3.59e-3)" "unprognostic (2.13e-2)" "unprognostic (1.91e-1)" "unprognostic (2.46e-1)" "unprognostic (9.62e-2)" 4.4 4.0 14.8 4.7 25.6 24.3 8.2 17.4 32.3 14.0 0.0 12.4 16.6 3.4 2.3 128.8 4.0 3.4 8.1 30.5 15.3 5.1 4.3 3.4 2.1 23.8 26.5 2.3 18.8 2.7 7.8 7.3 18.4 12.8 12.9 18.5 18.0 6.2 1.9 134.4 12.0 4.5 16.3 3.3 4.6 1.3 26.9 6.7 2.2 1.6 27.9 28.9 36.8 38.8 16.6 13.6 12.6 18.2 6.5 2.1 88.2 6.6 6.1 5.4 3.8 28.8 55.2 21.8 26.1 7.6 10.9 229.2 32.5 117.6 2.4 51.8 4.9 3.0 4.4 13.2 2.6 14.9 35.4 2.0 139.2 17.1 62.5 2.1 16.3 6.2 0.6 113.2 7.2 42.7 0.3 9.0 41.6 55.3 18.7 1.2 75.7 26.3 5.1 157.4 30.6 68.6 22.1 57.4 1.8 18.8 52.3 2.2 9.0 4.8 17.6 39.2 5.9 20.6 28.0 0.2 1.7 11.9 11.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 1.6 0.0 0.0 14.8 25.6 17.4 32.3 30.5 15.3 23.8 26.5 18.4 16.3 26.9 38.8 4.2 0.0 3.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 12.1 27.3 0.0 0.0 4.3 1.8 0.0 4.1 4.1 0.0 0.0 8.7 0.0 4.6 3.2 1.3 0.0 0.0 0.0 12.3 1.3 2.1 0.0 10.9 0.0 68.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.5 0.0 0.0 1.9 0.0 0.0 3.3 1.5 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 8.9 1.3 1.7 0.0 0.0 NECTIN4 "LNIR, nectin-4, PRR4, PVRL4" ENSG00000143217 "Nectin cell adhesion molecule 4" Q96NY8 1 161070998-161089558 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.9;skin 1: 113.6;vagina: 57.3" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 384.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 56.5;HaCaT: 37.0;MCF7: 24.0;OE19: 24.6;SK-BR-3: 47.8;T-47d: 31.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA010775 Enhanced Supported "Plasma membrane" "Secreted in other tissues" No No 170000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA010775: AB_1079720" "unprognostic (1.09e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.11e-2)" "unprognostic (5.69e-3)" "unprognostic (2.09e-2)" "unprognostic (6.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-3)" "unprognostic (1.13e-1)" "unprognostic (2.24e-8)" "unprognostic (2.98e-2)" "unprognostic (2.43e-1)" "unprognostic (3.68e-2)" "unprognostic (4.97e-2)" 0.4 0.1 0.1 0.5 0.1 0.7 13.7 0.3 0.2 26.5 0.0 1.5 0.7 1.2 6.9 98.9 2.9 3.8 0.1 0.1 0.0 3.1 0.1 3.5 0.1 0.1 0.1 0.0 4.5 0.4 0.6 12.2 0.1 9.4 1.7 0.1 33.6 4.3 0.6 113.6 0.6 0.1 0.0 0.0 8.8 0.6 0.3 0.8 0.2 0.0 14.5 16.8 57.3 0.4 10.9 0.4 0.0 0.1 0.0 0.1 56.5 0.1 0.1 0.1 0.2 0.0 14.6 0.0 0.2 0.0 0.1 37.0 0.0 1.2 0.2 0.0 0.5 0.0 0.8 11.1 0.0 0.1 0.7 0.0 14.6 3.0 3.6 0.1 0.0 0.0 0.0 0.1 0.1 24.0 0.1 0.1 0.1 24.6 0.0 0.0 0.0 0.1 0.0 17.5 0.0 0.2 0.2 47.8 0.0 6.4 31.1 0.0 0.0 0.1 2.4 0.5 0.2 0.2 0.1 0.1 0.1 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.4 0.2 6.4 9.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 41.6 17.8 0.0 0.0 8.1 16.5 0.0 39.4 0.4 0.0 0.0 41.7 0.0 28.1 2.9 0.6 0.0 0.0 0.0 30.0 67.1 1.2 0.0 43.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 67.1 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 384.2 0.4 0.1 0.0 0.0 NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "NEDD4 like E3 ubiquitin protein ligase" Q96PU5 18 58044226-58401540 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 253.2;Excitatory neurons: 280.9" "Cancer enhanced" "Detected in all" "prostate cancer: 29.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "T-reg: 5.1" "Lineage enriched" "Detected in many" 4 "T-cells: 5.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 146.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA024618: AB_1854362" "unprognostic (2.56e-1)" "unprognostic (2.41e-2)" "unprognostic (1.58e-2)" "unprognostic (3.14e-1)" "unprognostic (3.90e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-3)" "unprognostic (2.26e-2)" "unprognostic (9.24e-3)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.55e-15)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.49e-3)" "unprognostic (4.75e-2)" 11.2 16.8 20.9 6.7 34.4 27.0 25.8 25.1 31.3 7.6 0.7 38.8 18.7 5.3 10.0 12.0 9.1 9.5 26.9 32.3 16.2 53.4 36.5 47.9 4.1 10.9 18.4 6.4 60.5 13.6 28.4 12.0 10.4 64.2 42.8 20.5 27.5 20.4 34.0 11.2 33.8 6.2 8.6 7.9 51.5 7.8 16.7 4.5 17.4 13.1 7.9 19.4 5.9 16.3 70.7 24.5 14.6 20.9 5.1 2.1 49.8 19.2 88.2 48.6 74.6 28.6 37.1 15.1 57.7 7.4 51.3 50.3 19.5 86.1 100.8 34.9 15.5 10.6 14.3 111.3 2.4 0.5 6.0 13.0 54.6 66.4 78.8 39.1 4.0 13.2 18.7 6.3 20.0 16.2 1.0 1.0 12.2 26.7 33.3 14.3 20.1 17.6 47.0 88.7 17.5 5.0 16.1 5.1 146.1 28.3 29.4 5.6 28.8 131.5 38.5 7.5 83.4 8.3 15.3 9.5 27.6 10.8 10.8 0.7 0.3 1.2 0.2 0.3 0.5 0.8 0.6 0.1 0.1 0.3 0.3 0.2 0.2 0.3 0.1 0.1 5.1 0.3 20.9 34.4 25.1 31.3 32.3 16.2 10.9 18.4 10.4 8.6 16.7 16.3 6.0 253.2 144.8 110.4 5.1 112.8 161.2 34.0 86.6 18.1 99.5 65.9 47.8 64.3 112.8 62.5 173.0 13.0 3.6 144.5 49.0 35.7 22.6 64.0 7.3 14.7 45.2 57.9 280.9 49.2 4.7 9.5 114.7 75.0 3.8 4.7 17.5 41.3 7.3 62.2 173.3 201.5 101.7 8.4 8.2 6.6 3.4 13.3 14.2 88.1 7.3 45.2 2.1 11.1 105.0 49.9 145.3 17.7 12.7 126.9 127.3 91.6 72.7 10.0 0.0 34.3 6.0 1.1 12.5 62.3 53.0 80.0 6.6 8.2 72.9 155.5 NEK1 "KIAA1901, NY-REN-55" ENSG00000137601 "NIMA related kinase 1" Q96PY6 4 169392809-169612627 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Ciliopathy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 162.6;Excitatory neurons: 126.3;Inhibitory neurons: 170.5;Oligodendrocytes: 196.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020873, HPA040413" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Centriolar satellite" "HPA020873: AB_10671583, HPA040413: AB_10671169" "unprognostic (4.10e-2)" "unprognostic (2.97e-1)" "unprognostic (1.59e-2)" "unprognostic (1.97e-1)" "unprognostic (6.98e-2)" "unprognostic (3.10e-1)" "unprognostic (3.95e-1)" "unprognostic (3.29e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (4.06e-3)" "unprognostic (2.21e-1)" "prognostic favorable (1.42e-4)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.10e-2)" "unprognostic (3.46e-1)" 6.0 6.1 5.1 4.9 6.8 4.2 5.2 7.1 5.3 7.6 2.7 4.0 3.2 7.3 2.8 4.6 9.3 6.1 6.9 3.5 8.8 5.9 4.2 4.6 5.3 7.5 7.7 9.4 4.0 6.5 2.9 4.3 7.6 6.7 4.4 8.7 4.2 6.0 3.3 2.3 3.5 6.6 7.6 5.1 4.9 11.8 5.3 6.8 7.9 4.6 4.6 5.6 2.8 7.7 5.8 2.5 10.0 11.0 15.5 17.1 3.3 11.9 10.6 9.3 8.8 3.3 6.7 15.4 2.2 10.4 9.0 1.9 9.7 10.1 10.5 16.9 6.5 10.3 10.4 3.9 9.0 10.6 7.9 13.7 5.9 9.5 16.7 19.1 9.3 14.5 18.6 28.2 12.1 3.7 13.6 4.6 3.3 3.6 6.0 8.4 6.5 4.9 9.7 6.8 11.0 12.5 8.6 4.2 8.1 7.7 5.3 4.6 11.2 6.0 5.4 6.2 8.1 11.3 18.6 11.6 9.7 5.1 10.7 5.1 0.9 0.9 1.9 1.5 2.2 2.0 1.5 1.2 0.7 2.0 2.2 2.3 0.6 1.1 0.7 1.6 1.6 0.7 5.1 6.8 7.1 5.3 3.5 8.8 7.5 7.7 7.6 7.6 5.3 7.7 12.2 12.8 16.4 162.6 34.2 9.6 15.8 12.1 21.1 21.8 11.3 12.7 37.2 4.3 17.8 18.4 29.2 20.8 17.0 6.4 17.6 10.4 109.7 67.2 21.6 13.2 7.2 26.7 126.3 6.2 8.6 25.0 17.3 23.7 18.3 20.1 9.7 7.8 10.7 18.5 170.5 5.6 20.3 7.0 7.4 48.2 23.6 14.5 5.4 53.4 6.6 26.1 15.5 115.1 196.1 8.9 4.0 31.6 23.2 6.9 5.3 9.6 68.4 24.9 13.1 32.8 25.5 67.9 37.3 21.3 6.3 29.6 22.0 26.0 6.3 9.2 NEK8 NPHP9 ENSG00000160602 "NIMA related kinase 8" Q86SG6 17 28725897-28743455 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040661, HPA040679" Approved Approved "Nuclear speckles,Microtubules,Mitotic spindle" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Microtubules "Nuclear speckles, Mitotic spindle" "HPA040661: AB_10794065, HPA040679: AB_10796226" "unprognostic (2.63e-1)" "unprognostic (4.57e-2)" "prognostic unfavorable (6.98e-4)" "unprognostic (6.25e-2)" "unprognostic (2.23e-2)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "prognostic favorable (4.52e-4)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (1.51e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-3)" "unprognostic (4.61e-2)" "unprognostic (3.58e-1)" "unprognostic (1.75e-1)" "unprognostic (4.67e-3)" 1.5 3.1 1.7 3.3 1.9 1.7 2.4 1.4 1.9 2.5 3.8 2.4 3.0 1.5 3.2 2.5 3.9 2.0 1.0 1.4 1.6 9.1 5.2 3.3 5.8 2.0 1.7 1.9 4.5 2.9 4.4 2.6 1.7 4.0 2.2 0.6 3.7 2.6 0.5 3.1 4.2 1.2 1.6 5.8 3.4 3.8 1.9 2.7 7.2 0.4 5.0 2.6 2.2 2.3 2.1 3.4 3.5 2.8 1.9 2.1 10.9 0.9 2.1 1.3 1.7 5.4 5.0 13.1 3.5 2.8 2.5 3.8 5.2 4.8 1.3 3.5 6.4 2.9 5.8 10.1 3.3 1.8 3.7 4.8 1.8 2.5 5.8 1.8 0.9 1.9 4.3 1.3 1.5 4.7 1.9 3.4 3.3 3.7 1.0 4.9 2.3 5.9 7.0 5.7 6.4 1.5 3.0 6.3 1.6 4.7 9.3 2.4 0.8 1.3 2.2 1.6 1.0 1.5 1.8 8.9 2.0 1.6 3.1 3.3 0.9 1.2 0.7 0.5 0.8 2.8 0.6 0.7 0.1 4.2 0.7 1.0 0.4 1.3 1.1 14.8 0.5 0.8 1.7 1.9 1.4 1.9 1.4 1.6 2.0 1.7 1.7 1.6 1.9 2.3 2.7 9.6 19.3 3.9 22.9 2.8 9.2 8.3 7.4 2.8 10.1 14.1 1.7 12.8 11.6 25.8 8.4 17.6 19.1 14.9 7.9 5.8 9.5 12.8 6.0 2.9 10.3 7.0 0.7 6.0 9.2 3.9 6.1 15.2 26.6 3.2 3.3 9.4 3.9 1.7 0.5 14.4 10.2 5.0 2.7 2.0 3.4 4.4 3.6 2.8 4.0 2.6 3.1 1.5 1.6 3.9 17.2 2.6 7.2 8.6 13.4 4.3 14.3 1.8 0.0 11.7 3.0 19.9 11.4 8.8 1.6 11.1 4.9 7.8 15.9 4.2 NEK9 "DKFZp434D0935, MGC16714, Nek8, NERCC, NERCC1" ENSG00000119638 "NIMA related kinase 9" Q8TD19 14 75079353-75127344 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001405 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" "HPA001405: AB_1079467" "unprognostic (1.00e-1)" "unprognostic (5.37e-2)" "unprognostic (9.97e-3)" "unprognostic (2.64e-2)" "unprognostic (3.86e-1)" "unprognostic (2.77e-1)" "unprognostic (1.12e-1)" "unprognostic (5.60e-3)" "unprognostic (2.81e-1)" "unprognostic (1.15e-1)" "prognostic favorable (5.63e-4)" "unprognostic (8.58e-2)" "unprognostic (1.36e-2)" "unprognostic (4.54e-2)" "unprognostic (9.22e-2)" "unprognostic (2.61e-1)" "unprognostic (1.57e-2)" 24.2 18.5 6.7 18.6 8.4 11.8 17.3 7.5 7.9 24.3 9.0 14.3 15.5 26.0 10.5 17.8 25.2 17.9 37.2 6.1 7.8 18.4 21.0 18.8 21.0 8.2 7.7 35.8 16.0 34.2 3.1 21.2 7.9 23.5 16.3 16.5 12.4 28.1 43.6 8.1 16.9 32.2 7.5 19.7 13.1 20.4 7.7 28.3 19.7 36.9 23.5 16.3 2.9 9.1 21.3 30.8 44.8 45.4 86.3 88.8 37.9 32.4 54.6 29.7 29.4 25.5 24.7 52.7 0.1 54.2 23.1 31.8 45.0 27.0 38.5 38.2 16.8 23.0 27.3 17.3 48.6 10.8 26.8 76.6 32.8 31.8 26.7 71.6 46.1 36.2 23.8 31.4 40.2 4.8 35.5 11.5 21.9 43.3 18.8 53.5 49.4 23.9 21.3 28.2 19.5 41.3 39.5 19.3 30.0 50.4 41.7 37.6 46.3 30.2 12.7 31.5 15.8 34.3 36.5 49.6 24.9 24.8 26.4 3.4 3.5 3.1 2.5 3.4 4.0 1.3 2.4 2.3 5.0 1.9 3.1 2.8 1.2 3.3 2.5 1.1 1.5 2.9 6.7 8.4 7.5 7.9 6.1 7.8 8.2 7.7 7.9 7.5 7.7 9.1 15.3 12.8 30.2 49.3 21.2 8.8 7.7 6.6 21.1 16.8 14.5 12.4 55.7 12.8 14.8 11.0 35.5 17.4 11.1 10.2 7.9 6.9 11.9 13.3 23.1 17.6 5.4 16.2 31.3 4.9 16.2 18.1 10.7 10.4 16.4 36.8 17.9 30.3 13.9 13.5 35.9 10.7 6.1 18.6 11.8 8.3 24.8 17.0 3.6 30.9 16.0 12.0 15.5 41.2 59.5 5.3 11.7 26.4 14.7 7.4 13.1 8.4 17.4 23.1 0.0 18.9 16.7 28.8 13.9 17.4 10.2 14.0 16.5 20.8 10.5 5.6 NF1 ENSG00000196712 "Neurofibromin 1" P21359 17 31094927-31382116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 254.0;Excitatory neurons: 325.3;Inhibitory neurons: 412.5;Oligodendrocyte precursor cells: 428.2;Oligodendrocytes: 317.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045502 Uncertain Approved Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA045502: AB_2679352" "unprognostic (6.69e-2)" "unprognostic (8.73e-2)" "unprognostic (8.26e-2)" "unprognostic (1.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (1.30e-2)" "unprognostic (3.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (3.70e-1)" 7.4 8.4 8.9 7.1 10.7 3.4 11.5 13.2 12.2 10.0 1.6 8.5 6.8 10.2 10.0 6.1 9.0 8.0 11.3 9.7 11.7 12.0 9.4 7.3 7.7 11.7 9.2 13.5 10.4 15.9 7.8 12.4 9.1 9.5 8.8 20.9 9.1 9.5 8.1 7.4 7.5 8.7 8.2 7.1 8.2 10.0 11.8 13.5 19.5 10.6 7.8 10.4 6.8 14.4 15.8 20.3 24.2 13.1 20.1 25.8 12.2 13.4 24.1 19.5 21.8 18.4 10.5 15.2 3.8 25.1 22.9 26.8 22.2 18.7 32.6 7.5 14.1 13.4 18.8 9.5 14.2 24.4 10.6 20.7 11.8 20.8 25.1 21.8 9.5 15.7 19.8 14.8 18.8 12.4 20.4 8.8 7.1 9.7 6.8 15.8 36.8 12.3 14.7 22.5 10.0 14.9 25.4 8.3 13.8 16.8 25.0 15.3 14.1 15.3 21.5 18.8 5.1 13.2 6.9 16.3 12.6 10.0 16.2 4.4 0.3 0.6 1.5 0.1 1.0 1.4 2.8 2.5 0.4 1.2 2.0 2.0 0.7 0.7 0.3 0.4 5.9 0.6 8.9 10.7 13.2 12.2 9.7 11.7 11.7 9.2 9.1 8.2 11.8 14.4 30.9 32.1 31.1 254.0 18.3 38.6 48.1 38.9 31.9 62.7 33.7 24.9 43.9 41.5 29.8 40.5 137.6 57.5 23.8 37.8 23.5 27.1 210.4 27.4 39.4 35.8 19.8 9.7 325.3 22.5 26.6 39.1 39.3 45.8 10.8 44.0 33.2 35.7 22.5 70.7 412.5 24.3 38.7 27.6 34.1 94.6 37.3 28.2 21.4 215.5 20.9 47.5 21.6 428.2 317.4 33.3 43.0 50.4 30.8 54.2 32.1 28.6 36.9 62.8 46.0 51.9 43.3 30.5 28.7 19.8 34.0 49.3 19.8 36.1 27.4 64.5 NF2 "ACN, BANF, merlin, SCH" ENSG00000186575 "Neurofibromin 2" P35240 22 29603556-29698598 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 77.1;Late spermatids: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003097, CAB005385" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB005385: AB_2298548, HPA003097: AB_1079473" "unprognostic (3.27e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.14e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.61e-1)" "unprognostic (3.67e-2)" "unprognostic (2.16e-2)" "unprognostic (2.01e-3)" "unprognostic (4.66e-1)" "prognostic favorable (2.89e-5)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (9.62e-2)" 8.8 13.6 19.7 8.4 17.2 8.0 7.6 13.6 28.7 8.9 10.7 10.8 6.2 11.1 6.2 13.4 8.6 5.3 21.4 27.3 13.9 17.2 10.5 9.3 6.4 14.4 18.1 8.5 12.7 27.4 9.5 4.6 14.3 9.9 5.4 7.3 8.5 6.7 22.8 10.2 8.8 8.0 14.3 9.9 10.0 20.9 17.6 9.3 11.1 19.1 7.1 9.3 7.7 16.6 75.8 36.7 12.2 74.3 21.5 22.0 7.7 57.3 37.9 74.1 53.7 32.7 18.4 21.1 50.4 69.9 48.9 27.1 25.1 37.8 52.0 31.9 12.5 26.8 24.4 26.4 22.4 35.1 28.6 20.1 16.4 53.3 51.0 21.8 47.7 13.7 12.0 18.7 64.5 35.1 21.4 16.6 8.3 16.9 20.4 24.2 56.8 18.8 68.5 37.3 17.0 11.6 36.0 24.5 14.0 9.4 14.9 15.4 92.7 101.1 109.6 44.8 112.5 30.0 26.7 25.5 27.0 14.5 68.5 10.0 10.0 4.2 15.5 14.7 13.1 8.3 11.5 10.4 15.1 8.6 9.7 9.2 2.3 13.2 21.0 10.2 10.7 12.2 19.7 17.2 13.6 28.7 27.3 13.9 14.4 18.1 14.3 14.3 17.6 16.6 8.1 6.4 20.1 14.7 9.4 14.1 11.6 9.8 8.6 16.3 14.5 9.0 23.1 18.6 10.0 14.7 10.4 11.7 12.7 9.0 21.5 40.0 77.1 14.5 17.7 13.2 13.1 13.9 27.5 24.9 6.7 12.5 7.7 15.2 22.9 12.2 11.7 14.4 13.5 30.3 27.1 7.9 6.1 14.7 7.5 121.4 7.2 10.2 8.8 18.7 8.6 19.1 14.4 17.6 16.7 40.1 14.5 12.4 14.7 13.6 10.5 30.1 8.6 9.6 6.6 13.7 15.6 29.5 8.1 15.5 14.3 3.8 12.9 17.4 11.2 9.5 NFIX NF1A ENSG00000008441 "Nuclear factor I X" Q14938 19 12995475-13098796 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 410.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 145.2;Oligodendrocytes: 140.9;Skeletal myocytes: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 149.5;fHDF/TERT166: 211.3;U-138 MG: 191.5;U-2197: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007533 Supported Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA007533: AB_2667855" "unprognostic (3.32e-1)" "unprognostic (1.37e-2)" "unprognostic (2.84e-1)" "unprognostic (2.20e-1)" "unprognostic (2.29e-1)" "unprognostic (8.12e-2)" "prognostic favorable (4.66e-4)" "prognostic favorable (2.35e-4)" "unprognostic (1.26e-1)" "unprognostic (2.01e-2)" "unprognostic (3.25e-1)" "unprognostic (2.63e-2)" "unprognostic (1.08e-2)" "unprognostic (3.46e-2)" "unprognostic (2.92e-2)" "unprognostic (3.06e-2)" "unprognostic (4.38e-2)" 76.4 14.9 30.4 19.7 80.2 14.9 48.0 99.8 97.7 67.2 4.0 60.4 20.9 88.5 10.9 72.4 69.5 53.9 60.9 54.0 15.0 8.9 20.3 50.0 6.2 50.9 45.1 73.8 23.8 13.2 18.9 11.8 39.4 85.0 19.7 11.7 150.4 60.0 410.3 99.2 24.3 67.8 45.6 11.3 37.3 16.0 46.9 11.6 31.0 138.2 6.2 45.0 52.7 105.2 39.2 16.2 1.0 119.9 111.7 149.5 1.3 48.1 68.6 45.7 31.8 1.3 3.3 0.6 13.4 211.3 31.4 17.5 12.8 37.4 20.1 25.8 19.7 20.2 7.6 17.2 53.8 8.5 10.3 99.0 10.9 44.1 24.6 80.3 12.4 8.6 6.7 6.2 29.3 12.1 14.9 5.7 0.5 8.6 132.3 43.5 22.2 23.1 0.4 8.5 17.9 47.6 34.5 0.3 43.0 0.0 22.7 17.3 12.2 191.5 23.5 185.1 68.5 4.5 1.7 0.3 49.9 12.1 62.0 0.1 0.1 0.0 0.5 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 30.4 80.2 99.8 97.7 54.0 15.0 50.9 45.1 39.4 45.6 46.9 105.2 19.5 12.8 59.3 62.7 6.8 58.8 45.5 22.4 134.9 13.3 57.9 74.2 33.2 27.1 15.9 14.7 4.2 0.2 3.7 16.5 1.9 24.3 64.0 12.1 40.1 20.0 12.1 145.2 69.0 12.7 0.3 89.7 32.6 3.0 3.8 4.3 17.9 33.9 1.0 0.0 38.1 25.8 2.0 4.1 15.2 43.1 112.2 5.8 26.6 17.8 1.9 93.7 0.0 52.3 140.9 15.2 12.0 126.0 2.5 60.3 8.4 10.0 19.0 3.0 6.6 174.7 38.3 15.6 13.2 99.4 51.4 0.3 3.8 56.0 29.5 31.8 NHS ENSG00000188158 "NHS actin remodeling regulator" Q6T4R5 X 17375200-17735994 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Inhibitory neurons: 264.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "EFO-21: 12.7;RPTEC TERT1: 19.2;RT4: 12.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031497, HPA076257" Uncertain Supported "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "HPA031497: AB_10610144, HPA076257: AB_2686789" "unprognostic (1.39e-2)" "unprognostic (3.34e-1)" "unprognostic (1.17e-1)" "prognostic favorable (1.68e-4)" "unprognostic (2.58e-1)" "unprognostic (1.69e-1)" "unprognostic (9.92e-3)" "unprognostic (3.27e-3)" "unprognostic (1.08e-1)" "unprognostic (1.78e-1)" "unprognostic (1.61e-3)" "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-2)" "unprognostic (1.21e-1)" "unprognostic (8.83e-3)" "unprognostic (1.83e-3)" 3.2 4.1 2.9 1.3 2.4 0.4 2.8 0.0 4.2 6.1 6.8 4.1 0.8 4.8 2.8 1.8 2.7 1.6 0.9 1.8 2.5 5.1 0.2 1.1 0.5 3.3 2.8 3.5 0.5 0.3 2.8 2.6 3.0 3.4 1.6 7.8 2.0 2.7 0.4 2.3 1.5 2.5 1.7 1.0 2.2 2.5 3.8 2.2 2.6 0.7 0.5 4.0 3.7 0.9 7.9 3.1 5.5 0.0 0.1 0.2 8.7 3.5 2.4 1.5 0.8 0.3 1.5 0.5 12.7 2.4 7.5 6.8 3.5 4.4 2.2 0.1 1.1 0.0 5.4 0.0 0.0 0.0 0.0 0.7 3.1 0.1 6.8 6.7 0.0 0.0 0.0 0.0 0.8 3.8 0.0 0.0 6.7 3.6 2.0 0.0 0.0 0.3 19.2 12.0 1.4 2.8 9.6 0.0 0.0 3.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 8.0 0.1 8.4 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.1 2.9 2.4 0.0 4.2 1.8 2.5 3.3 2.8 3.0 1.7 3.8 0.9 0.6 3.2 0.0 22.5 0.0 8.3 10.6 4.6 8.6 11.4 2.0 2.4 1.7 0.0 14.7 1.8 22.9 6.0 0.1 1.3 5.9 0.8 0.9 12.4 20.1 3.5 4.2 0.0 40.1 2.2 5.4 6.1 3.6 25.0 0.0 0.2 0.7 0.0 1.4 3.3 264.4 1.9 2.0 4.6 2.6 2.3 16.8 2.4 3.6 40.3 5.0 11.9 0.0 14.1 8.1 6.8 2.4 31.2 0.0 7.0 0.9 7.8 8.2 18.9 6.6 2.0 11.9 0.3 0.6 5.1 3.8 2.6 0.9 4.5 4.3 12.8 NIN ENSG00000100503 Ninein Q8N4C6 14 50719763-50831162 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 240.5;Muller glia cells: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 31.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005939, HPA070691" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Centrosome" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim, Centrosome" Nucleoplasm "HPA005939: AB_2667474, HPA070691: AB_2686296" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (3.54e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (1.43e-2)" "unprognostic (3.41e-2)" "unprognostic (3.31e-1)" "unprognostic (5.81e-3)" "unprognostic (1.78e-2)" "unprognostic (2.07e-1)" "unprognostic (4.06e-1)" "unprognostic (2.46e-2)" "unprognostic (2.67e-1)" "unprognostic (1.28e-1)" "unprognostic (2.58e-2)" "unprognostic (7.66e-3)" 11.2 4.4 10.1 19.9 10.8 43.2 8.9 9.5 15.0 7.2 0.0 8.3 4.8 7.7 2.8 12.9 10.5 8.9 18.2 10.4 0.9 6.7 5.7 9.5 25.9 0.0 1.3 9.7 7.2 9.0 8.9 16.8 0.0 6.9 8.6 19.1 5.4 5.4 6.0 12.9 7.1 10.3 0.0 16.2 9.3 5.2 3.0 19.9 7.7 7.4 23.7 13.6 5.7 7.5 29.1 21.6 42.4 36.8 16.7 26.8 20.4 26.5 22.1 21.4 18.0 14.7 14.6 48.5 17.7 35.5 19.9 32.5 34.2 16.3 45.3 34.7 10.4 25.1 13.2 12.3 9.8 41.6 57.5 18.4 11.4 37.2 14.9 13.3 34.6 25.9 6.6 26.3 31.8 36.8 22.6 14.0 6.4 10.1 23.6 37.1 81.6 5.7 20.1 42.9 18.6 22.2 34.0 9.6 25.1 10.2 21.2 39.3 50.9 55.2 74.3 20.5 29.0 18.6 12.1 34.3 14.4 32.8 30.4 31.9 2.9 24.0 3.9 2.5 3.3 8.9 2.4 6.2 2.0 6.2 5.1 4.7 9.6 2.9 2.1 7.7 2.5 1.4 10.1 10.8 9.5 15.0 10.4 0.9 0.0 1.3 0.0 0.0 3.0 7.5 34.0 6.4 7.7 100.2 85.6 18.4 9.1 10.2 18.8 13.3 13.3 10.9 68.0 14.3 27.1 11.0 62.6 12.4 102.7 8.7 3.9 7.3 22.2 17.3 28.5 26.7 12.6 29.0 240.5 4.2 11.3 32.9 7.7 14.9 31.6 3.9 21.8 4.4 22.7 6.7 110.4 5.7 20.3 46.8 42.2 10.4 8.4 61.3 23.2 63.7 63.2 150.2 57.7 105.6 75.1 5.2 6.2 9.4 48.1 16.5 3.2 7.3 29.4 21.0 32.9 44.9 24.1 0.2 4.3 20.1 21.0 9.7 56.2 21.8 6.9 15.5 NIPAL4 ICHYN ENSG00000172548 "NIPA like domain containing 4" Q0D2K0 5 157460213-157474722 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" Receptor "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.7;skin 1: 61.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 29.7;Basal prostatic cells: 9.8;Oligodendrocytes: 21.0;Squamous epithelial cells: 9.8;Suprabasal keratinocytes: 42.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.0;urothelial cancer: 11.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 25 "memory B-cell: 1.6;naive B-cell: 4.8" "Lineage enriched" "Detected in single" 37 "B-cells: 4.8" "Group enriched" "Detected in some" 8 "hTCEpi: 31.7;RT4: 108.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038259 Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 28: Keratinocytes - Keratinization" "HPA038259: AB_10672510" "unprognostic (6.74e-4)" "unprognostic (9.54e-2)" "unprognostic (2.63e-2)" "unprognostic (1.49e-1)" "unprognostic (2.61e-1)" "unprognostic (6.56e-2)" "unprognostic (3.55e-2)" "unprognostic (5.20e-2)" "unprognostic (2.53e-1)" "unprognostic (2.99e-2)" "unprognostic (1.92e-1)" "unprognostic (1.76e-2)" "unprognostic (5.28e-9)" "unprognostic (3.12e-2)" "unprognostic (8.66e-3)" "unprognostic (1.18e-2)" "prognostic favorable (6.82e-4)" 0.4 0.0 3.5 2.0 9.7 3.4 2.2 8.5 7.1 5.9 1.1 3.7 0.3 1.2 0.1 15.1 0.1 0.5 1.5 3.9 6.2 0.0 0.0 0.7 0.4 12.4 8.7 0.0 0.0 0.0 0.5 0.6 10.5 1.5 0.6 0.1 1.9 1.4 0.2 61.2 0.9 1.1 7.6 0.2 2.5 0.1 8.0 0.4 0.3 0.0 5.8 11.5 15.1 18.7 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.4 0.1 1.1 0.0 0.0 0.7 0.4 0.0 6.3 0.3 2.7 0.6 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.3 31.7 0.0 1.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 108.1 0.0 0.4 0.0 0.0 0.0 8.5 1.6 0.0 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.5 9.7 8.5 7.1 3.9 6.2 12.4 8.7 10.5 7.6 8.0 18.7 0.0 0.0 0.5 0.0 2.4 29.7 9.8 0.6 2.2 0.6 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.7 0.3 0.0 1.1 1.8 0.0 0.0 0.0 0.0 0.0 21.0 0.1 0.0 0.0 0.3 3.8 0.0 0.0 0.1 1.1 0.0 5.2 0.3 0.0 0.1 9.8 42.1 0.0 0.2 0.0 0.0 4.4 NIPBL "DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, IDN3, Scc2" ENSG00000164190 "NIPBL cohesin loading factor" Q6KC79 5 36876769-37066413 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Activator, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 303.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040834, HPA058239" Approved Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA040834: AB_10796562, HPA058239: AB_2683650" "unprognostic (4.92e-2)" "unprognostic (9.77e-2)" "unprognostic (5.28e-2)" "unprognostic (8.10e-2)" "unprognostic (9.38e-2)" "unprognostic (6.02e-2)" "unprognostic (7.34e-2)" "unprognostic (3.04e-2)" "unprognostic (3.85e-2)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" "unprognostic (3.41e-1)" "unprognostic (1.04e-1)" "unprognostic (3.40e-2)" 11.5 9.4 5.6 14.7 8.6 25.1 13.5 12.0 7.3 12.9 7.8 12.2 10.0 13.4 6.6 11.4 10.5 11.1 7.7 5.3 5.9 11.6 12.7 11.9 16.5 7.3 6.6 17.6 13.1 19.6 5.0 13.9 8.2 11.1 12.2 22.4 11.2 10.7 9.5 14.2 13.2 12.4 6.3 15.3 13.4 14.2 6.9 29.8 17.2 14.3 16.7 12.6 7.5 11.1 22.5 13.1 33.3 15.6 20.7 22.3 24.4 17.6 19.3 18.9 15.7 18.2 22.6 33.5 11.3 21.6 22.2 19.2 28.9 15.9 27.0 27.9 14.7 40.9 57.4 13.3 14.0 48.4 26.4 16.5 19.3 21.3 28.1 18.1 24.0 20.8 39.3 24.5 17.9 10.8 33.8 18.1 16.0 12.9 11.3 28.2 51.9 13.0 13.1 31.4 24.5 17.2 84.6 22.5 18.0 26.2 23.0 27.3 26.3 24.9 27.1 21.0 13.3 17.7 25.5 39.1 13.6 32.4 19.1 10.9 2.9 4.3 3.2 2.2 3.0 2.8 2.7 2.9 2.3 3.1 2.9 3.3 7.7 2.8 3.3 3.4 2.1 1.6 5.6 8.6 12.0 7.3 5.3 5.9 7.3 6.6 8.2 6.3 6.9 11.1 80.6 131.4 108.6 169.8 84.8 48.4 66.2 34.2 58.1 62.6 43.6 49.4 87.0 38.6 63.3 33.1 77.2 44.1 107.1 45.9 5.9 55.5 13.4 72.9 75.7 74.1 41.5 85.4 179.2 46.7 34.1 64.3 61.2 91.7 84.0 77.7 44.6 28.2 37.1 40.4 165.5 46.3 38.7 51.8 46.6 15.1 66.5 86.7 24.9 236.1 103.3 49.2 97.9 229.2 303.7 55.0 48.6 56.4 84.5 66.4 45.2 12.2 65.2 72.8 52.6 102.9 80.1 185.8 133.6 58.2 47.0 75.9 92.0 73.8 42.9 88.0 NKX2-5 "CSX, CSX1, NKX2.5, NKX2E, NKX4-1" ENSG00000183072 "NK2 homeobox 5" P52952 5 173232109-173235311 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Atrial septal defect, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "heart muscle: 229.0" "Cell type enriched" "Detected in some" 26 "Cardiomyocytes: 68.4" "Cancer enhanced" "Detected in many" "glioma: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 32.9;NTERA-2: 11.4;SK-MEL-30: 15.2;U-2 OS: 25.4;U-251 MG: 20.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA065034 Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA065034: AB_2685409" "unprognostic (3.81e-1)" "unprognostic (8.53e-2)" "unprognostic (2.62e-2)" "unprognostic (9.57e-3)" "unprognostic (3.22e-3)" "unprognostic (6.63e-2)" "unprognostic (1.57e-1)" "unprognostic (2.72e-1)" "unprognostic (2.31e-1)" "unprognostic (5.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.77e-2)" 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 229.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 34.9 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 5.0 1.7 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 7.6 32.9 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.2 0.2 0.0 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.1 0.5 6.3 0.0 15.2 4.2 0.0 0.1 0.0 5.9 25.4 7.8 20.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 68.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.1 0.0 0.1 0.1 0.0 0.7 0.0 0.0 NKX3-2 "BAPX1, NKX3.2, NKX3B" ENSG00000109705 "NK3 homeobox 2" P78367 4 13540830-13544508 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 18.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 1.2;Cardiomyocytes: 4.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 4.3;NB-4: 11.3;NTERA-2: 6.2;THP-1: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA027564 Approved Approved Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "HPA027564: AB_10601973" "unprognostic (3.26e-2)" "unprognostic (1.26e-1)" "unprognostic (7.42e-3)" "unprognostic (5.97e-2)" "unprognostic (9.15e-3)" "unprognostic (5.72e-2)" "unprognostic (2.24e-5)" "unprognostic (3.49e-2)" "unprognostic (1.12e-1)" "unprognostic (4.06e-2)" "unprognostic (9.95e-2)" "unprognostic (1.80e-1)" "unprognostic (1.93e-8)" "unprognostic (5.81e-2)" "unprognostic (2.14e-1)" "unprognostic (3.08e-2)" "unprognostic (2.15e-1)" 1.9 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.9 0.0 18.7 0.6 0.4 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.2 0.1 0.6 0.0 0.0 0.4 1.0 0.0 0.1 0.2 0.0 0.1 1.8 1.4 0.0 2.3 1.8 0.7 0.0 0.0 0.2 0.4 0.0 0.0 1.4 0.0 0.0 0.4 2.0 1.8 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.9 0.0 4.3 0.0 0.0 0.0 2.2 0.6 1.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.6 0.0 0.5 1.4 0.0 0.6 0.0 0.3 11.3 6.2 0.0 0.5 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.9 6.6 0.0 0.5 2.5 0.1 0.4 1.7 0.0 0.0 0.4 0.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.3 4.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 NODAL ENSG00000156574 "Nodal growth differentiation factor" Q96S42 10 70431936-70447951 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3;skeletal muscle: 2.3" "Group enriched" "Detected in some" 26 "Early spermatids: 15.4;Late spermatids: 38.5" "Cancer enriched" "Detected in some" 10 "testis cancer: 20.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.9;SH-SY5Y: 1.4;SuSa: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA045201 Uncertain "Secreted to blood" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "HPA045201: AB_2679252" "unprognostic (3.07e-2)" "unprognostic (2.10e-1)" "unprognostic (1.51e-2)" "unprognostic (2.41e-1)" "unprognostic (1.70e-1)" "unprognostic (4.57e-2)" "unprognostic (1.50e-1)" "unprognostic (1.65e-1)" "unprognostic (5.66e-3)" "unprognostic (3.12e-2)" "unprognostic (8.77e-2)" "unprognostic (1.61e-1)" "unprognostic (1.63e-5)" "unprognostic (4.37e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (2.02e-1)" 0.7 0.0 0.7 0.0 0.6 0.6 0.5 2.3 0.6 0.6 0.0 0.4 0.2 0.3 0.0 0.3 0.3 0.2 0.3 0.5 0.6 0.1 0.1 0.4 0.2 0.7 0.6 0.3 0.1 0.0 0.1 0.2 0.7 0.2 0.0 1.3 0.2 0.0 2.3 1.0 0.2 0.0 0.5 0.2 0.2 1.9 0.6 0.2 0.1 0.0 0.0 0.4 0.4 0.6 0.3 0.2 0.8 0.9 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.9 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.2 0.1 0.2 0.5 0.2 0.0 0.2 0.2 0.5 0.0 0.1 0.1 1.4 0.4 0.1 0.0 3.5 0.4 0.1 0.0 0.0 0.2 0.1 0.1 0.5 1.1 1.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.6 2.3 0.6 0.5 0.6 0.7 0.6 0.7 0.5 0.6 0.6 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 38.5 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 NOG "SYM1, SYNS1" ENSG00000183691 Noggin Q13253 17 56593699-56595611 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation" "Developmental protein" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2;placenta: 10.6" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 12.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 72.8;naive CD8 T-cell: 34.9" "Lineage enriched" "Detected in single" 78 "T-cells: 72.8" "Cell line enhanced" "Detected in many" "EFO-21: 123.3;LHCN-M2: 38.1;NB-4: 28.8;PC-3: 37.9;U-2 OS: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061318 Approved "Secreted to blood" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 32: Non-specific - Translation" "HPA061318: AB_2684478" "unprognostic (1.49e-1)" "unprognostic (1.17e-2)" "unprognostic (1.49e-5)" "prognostic favorable (6.66e-4)" "unprognostic (4.69e-2)" "unprognostic (5.23e-3)" "unprognostic (1.26e-2)" "unprognostic (3.06e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (6.86e-5)" "unprognostic (2.88e-1)" "unprognostic (1.14e-6)" "unprognostic (8.39e-2)" "unprognostic (1.40e-1)" "unprognostic (5.00e-1)" "unprognostic (1.65e-1)" 0.7 0.1 6.1 0.6 4.8 0.2 0.3 1.7 4.2 4.7 0.3 0.3 0.1 0.3 0.1 0.2 0.5 0.0 0.5 4.0 3.6 0.4 0.1 0.7 1.8 2.1 5.0 0.0 0.1 0.0 0.7 10.6 1.8 0.8 0.0 0.0 0.3 1.4 3.5 0.3 0.5 0.1 2.4 0.7 0.9 0.7 8.2 0.6 0.4 0.8 0.4 0.8 2.7 2.0 6.3 0.2 0.2 0.0 0.2 0.0 0.0 3.2 3.5 1.2 1.3 0.4 1.2 0.0 123.3 1.5 4.8 0.5 2.2 0.3 3.4 0.1 2.2 0.0 5.2 0.0 0.0 0.9 0.0 0.5 0.7 0.0 0.5 0.4 0.1 0.1 0.0 0.0 38.1 0.2 1.1 28.8 2.6 0.0 37.9 17.0 11.6 0.0 2.9 0.0 0.2 0.0 6.5 0.1 0.0 9.9 0.1 0.5 0.7 2.3 38.5 0.2 2.7 0.0 0.1 0.4 0.0 3.2 0.0 0.9 0.1 0.2 0.6 0.2 0.2 0.1 4.3 0.5 0.1 0.1 72.8 34.9 0.8 0.4 0.3 0.3 3.4 3.1 6.1 4.8 1.7 4.2 4.0 3.6 2.1 5.0 1.8 2.4 8.2 2.0 0.4 0.0 0.0 2.0 0.3 0.0 0.4 0.0 0.6 0.0 0.1 0.9 1.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.5 0.1 0.6 1.5 0.3 0.0 2.5 0.2 0.0 12.2 1.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 1.0 1.5 0.1 0.6 0.0 0.0 0.3 0.3 0.0 0.4 0.0 0.0 0.0 2.3 0.4 0.0 1.7 0.4 0.1 0.8 2.0 0.0 0.0 0.1 NOTCH1 TAN1 ENSG00000148400 "Notch receptor 1" P46531 9 136494433-136546048 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.2;Astrocytes: 67.3;Hepatic stellate cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 47.0;HDLM-2: 32.3;HMC-1: 39.7;MOLT-4: 72.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008112, CAB022466, HPA067168" Supported Approved Nucleoplasm NA NA 29000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB008112: AB_2153490, CAB022466: , HPA067168: AB_2685795" "unprognostic (1.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.16e-1)" "unprognostic (8.38e-3)" "unprognostic (3.04e-1)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-3)" "unprognostic (5.50e-3)" "unprognostic (8.78e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.14e-2)" "unprognostic (1.92e-1)" "unprognostic (5.65e-2)" "unprognostic (8.84e-2)" 18.2 4.2 10.4 4.9 16.1 4.3 15.0 12.1 9.3 14.3 0.0 19.8 4.3 12.7 0.2 16.3 11.9 0.9 14.9 8.6 5.5 11.8 9.2 22.2 3.0 13.5 12.3 5.1 14.0 0.7 6.3 2.6 9.8 15.4 0.6 0.6 10.7 3.1 5.0 24.2 14.2 1.3 9.7 24.8 10.0 2.5 13.9 4.0 11.2 1.2 0.9 14.2 16.5 14.0 8.8 10.6 4.0 2.6 0.0 0.4 17.7 3.3 0.4 1.4 0.4 1.8 0.9 13.3 10.3 1.3 1.6 47.0 1.0 8.6 0.1 32.3 2.0 5.5 6.1 0.6 2.1 6.9 39.7 0.3 16.7 1.4 1.9 0.7 9.0 3.7 3.6 1.1 0.0 9.0 72.3 13.1 8.4 2.9 7.7 15.7 9.2 19.3 0.6 4.2 0.0 0.7 6.1 4.3 3.4 1.0 3.2 10.4 22.7 5.0 9.3 5.9 4.3 2.4 2.6 4.1 3.7 5.0 26.1 0.2 0.4 0.6 0.3 0.1 0.1 0.1 0.1 0.5 0.3 0.0 0.1 0.3 2.3 0.7 0.1 0.1 0.1 0.5 10.4 16.1 12.1 9.3 8.6 5.5 13.5 12.3 9.8 9.7 13.9 14.0 56.2 9.6 21.9 67.3 8.4 24.9 12.3 35.1 23.9 0.8 10.7 12.4 11.0 5.7 16.3 1.8 2.1 1.1 14.2 11.8 0.0 5.1 0.3 12.3 9.9 53.2 2.4 5.2 0.3 4.0 2.2 6.4 1.1 17.3 34.9 1.0 68.2 7.7 9.3 1.7 0.4 14.8 18.3 10.1 17.5 0.3 1.2 15.2 7.2 18.7 14.3 46.6 24.7 33.7 19.6 2.1 11.5 0.7 5.7 8.4 4.1 3.4 3.8 2.0 6.6 14.7 18.4 0.2 3.3 20.6 29.8 1.1 15.0 1.4 28.8 15.6 NOTCH2 ENSG00000134250 "Notch receptor 2" Q04721 1 119911553-120100779 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048743 Approved Supported "Nucleoplasm,Plasma membrane" NA NA 160000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "HPA048743: AB_2680508" "unprognostic (1.33e-1)" "unprognostic (1.43e-2)" "unprognostic (2.66e-1)" "unprognostic (1.40e-3)" "unprognostic (7.98e-2)" "unprognostic (4.01e-2)" "unprognostic (1.22e-1)" "unprognostic (7.32e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.24e-4)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.86e-2)" "unprognostic (6.12e-3)" "unprognostic (1.55e-2)" "unprognostic (2.65e-2)" "unprognostic (1.12e-2)" "unprognostic (7.35e-3)" 27.1 12.9 16.4 20.4 13.6 13.7 24.8 11.9 16.4 31.0 20.3 16.0 5.4 21.2 20.8 24.9 25.7 18.5 14.2 15.9 13.7 10.9 19.6 20.2 16.7 20.6 18.6 33.9 20.1 12.1 5.5 24.9 13.9 20.4 13.6 19.3 17.1 22.2 6.4 32.3 11.9 26.6 15.7 25.3 10.5 25.4 19.3 15.3 21.2 8.9 17.9 19.0 24.1 14.8 54.2 17.7 27.0 20.7 108.5 92.7 26.6 39.7 54.8 51.8 55.8 16.3 14.2 1.4 32.6 75.3 46.2 20.1 42.8 35.3 82.5 64.0 27.2 32.1 45.7 1.6 40.5 32.7 8.0 75.5 22.5 155.2 103.7 78.4 26.9 14.5 0.8 65.3 63.7 59.2 13.9 9.2 34.6 5.0 19.6 9.1 94.2 36.1 27.3 33.4 1.1 13.4 54.5 50.0 27.9 53.4 28.0 11.7 97.0 67.0 45.8 102.7 63.1 27.9 16.8 16.5 98.7 29.5 65.2 15.0 14.9 22.9 1.4 7.3 1.4 39.0 1.6 0.9 23.7 33.3 3.1 2.0 8.9 2.4 10.5 12.3 3.8 4.4 16.4 13.6 11.9 16.4 15.9 13.7 20.6 18.6 13.9 15.7 19.3 14.8 4.6 35.3 19.5 125.4 36.6 46.3 56.6 14.8 31.3 3.3 38.1 25.3 16.0 24.3 28.5 18.4 6.2 1.6 26.0 6.2 0.0 46.8 17.7 33.8 21.9 5.4 6.1 18.3 4.2 12.9 8.9 67.8 5.1 61.1 15.8 78.3 3.9 41.5 32.7 3.3 22.6 7.9 20.3 74.7 78.2 12.6 55.0 76.6 39.2 43.1 79.3 46.2 15.5 75.4 0.6 26.8 105.5 85.4 14.2 37.2 3.2 4.9 16.4 10.5 19.7 83.6 34.0 10.0 4.3 75.1 88.9 1.6 18.5 22.0 15.8 66.9 NOTCH3 "CADASIL, CASIL" ENSG00000074181 "Notch receptor 3" Q9UM47 19 15159038-15200995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 414.2;Skeletal myocytes: 131.6;Smooth muscle cells: 317.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;MCF7: 66.9;RT4: 41.2;U-87 MG: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005393, HPA044392" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA 46000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Actin filaments" "CAB005393: AB_2151246, HPA044392: AB_2678926" "unprognostic (4.97e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (9.20e-2)" "unprognostic (1.73e-2)" "unprognostic (2.72e-1)" "unprognostic (9.04e-2)" "unprognostic (3.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (3.13e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (3.35e-2)" "unprognostic (8.34e-3)" "unprognostic (4.40e-2)" "unprognostic (2.00e-3)" 85.7 5.3 14.8 10.4 12.4 0.2 50.5 11.0 21.3 49.4 7.1 14.8 5.5 39.9 16.9 74.3 35.8 23.5 43.6 9.5 11.3 26.0 3.2 38.3 9.2 12.0 15.2 18.9 10.7 12.6 10.3 59.8 14.3 22.0 4.2 0.5 24.4 16.5 29.7 82.1 14.3 16.9 8.2 15.0 11.6 3.8 15.8 34.1 32.3 25.1 10.4 26.3 55.1 10.0 13.0 8.1 66.3 30.3 9.2 7.3 29.8 10.2 0.4 0.4 0.3 15.6 13.4 0.4 7.7 18.9 0.1 15.1 12.1 0.2 0.6 0.1 3.1 0.4 12.4 3.5 4.5 0.0 1.2 8.4 7.3 15.5 1.6 0.6 0.8 4.6 0.5 0.6 1.2 66.9 15.9 0.1 38.8 11.2 0.0 0.1 3.7 0.3 0.0 41.2 1.9 21.4 0.1 37.8 0.0 19.6 40.3 0.1 0.0 1.9 21.0 0.3 0.1 0.1 0.7 0.0 45.7 0.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 14.8 12.4 11.0 21.3 9.5 11.3 12.0 15.2 14.3 8.2 15.8 10.0 39.6 9.6 1.5 5.9 0.4 24.1 7.8 17.8 4.6 0.4 41.5 30.7 60.7 0.0 28.5 16.5 0.0 20.2 1.0 0.0 5.9 14.8 0.5 4.8 13.5 32.0 0.0 0.0 0.6 0.0 3.9 24.2 2.0 11.8 0.0 5.9 4.2 0.0 2.8 0.0 0.3 0.3 6.1 10.4 12.3 0.1 9.0 4.1 17.8 13.1 0.7 0.8 0.0 0.0 0.2 0.9 0.1 11.7 0.0 13.0 0.1 0.0 4.2 0.8 414.2 131.6 317.0 0.9 1.2 72.1 72.2 31.5 2.0 1.2 0.2 36.0 NOVA2 "ANOVA, NOVA-2, NOVA3" ENSG00000104967 "NOVA alternative splicing regulator 2" Q9UNW9 19 45933734-45974044 "Human disease related genes, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7" "Cell type enhanced" "Detected in some" "Adipocytes: 39.4;Bipolar cells: 56.7;Endothelial cells: 32.0;Excitatory neurons: 21.8;Hepatic stellate cells: 42.5;Horizontal cells: 21.9;Inhibitory neurons: 20.9" "Cancer enriched" "Detected in many" 4 "glioma: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.7;HDLM-2: 11.0;HUVEC TERT2: 16.9;SH-SY5Y: 5.6;TIME: 25.8;U-2 OS: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045607 Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "HPA045607: AB_10962628" "unprognostic (9.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (3.04e-3)" "unprognostic (1.46e-1)" "unprognostic (6.21e-2)" "unprognostic (2.36e-1)" "unprognostic (3.02e-3)" "unprognostic (6.42e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (5.05e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-1)" "unprognostic (8.31e-2)" 6.7 1.9 12.4 0.7 15.1 0.0 5.7 0.5 16.7 3.2 0.0 1.8 0.6 3.4 0.6 1.4 2.9 1.4 6.7 16.0 5.8 4.7 1.0 9.3 0.5 4.6 3.0 1.2 1.1 1.0 6.2 3.9 3.6 2.3 0.5 5.6 1.1 0.8 2.3 1.1 1.7 2.0 0.6 1.5 1.5 2.0 4.6 0.4 4.5 2.5 0.2 2.5 2.0 9.8 0.0 0.1 9.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 1.3 0.0 0.0 11.0 0.4 0.0 0.1 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 25.8 0.0 5.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 15.1 0.5 16.7 16.0 5.8 4.6 3.0 3.6 0.6 4.6 9.8 39.4 0.0 0.0 5.9 0.1 0.6 0.2 0.0 0.6 56.7 0.1 0.5 3.4 1.5 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.1 32.0 0.0 0.0 21.8 0.2 0.0 1.2 0.0 0.1 0.0 0.1 42.5 0.5 0.1 21.9 20.9 0.0 0.0 1.6 1.5 3.5 0.0 0.1 0.0 9.4 0.0 1.3 0.0 11.6 9.5 0.2 0.0 0.4 1.2 0.3 0.0 0.0 0.0 3.3 0.0 0.6 0.6 2.4 2.3 0.3 0.1 0.0 0.5 0.4 0.0 0.3 NPHP1 "JBTS4, NPH1, SLSN1" ENSG00000144061 "Nephrocystin 1" O15259 2 110122311-110205066 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Ciliopathy, Disease variant, Joubert syndrome, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 36.2" "Cell type enhanced" "Detected in many" "Early spermatids: 148.5;Endometrial ciliated cells: 136.3;Respiratory ciliated cells: 167.4;Spermatocytes: 146.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046093, HPA074071" Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "HPA046093: AB_2679535, HPA074071: " "unprognostic (2.10e-2)" "unprognostic (1.96e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (5.58e-2)" "unprognostic (4.63e-2)" "unprognostic (1.56e-3)" "unprognostic (4.66e-2)" "unprognostic (1.64e-2)" "unprognostic (1.16e-1)" "unprognostic (1.66e-2)" "unprognostic (1.29e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-3)" "unprognostic (3.35e-2)" "unprognostic (1.82e-1)" "unprognostic (8.64e-2)" 3.1 3.7 4.5 1.0 4.7 0.1 4.0 4.0 8.6 4.7 11.1 5.3 1.0 5.4 9.0 1.3 17.1 3.3 4.8 4.6 5.2 8.0 0.8 4.3 0.9 5.4 5.8 4.5 3.2 17.0 11.7 1.3 5.0 4.4 1.7 10.8 2.5 4.7 36.2 1.7 1.9 4.6 4.6 1.9 3.6 24.9 5.5 1.1 7.4 10.8 0.6 4.1 2.7 4.6 9.8 3.1 5.9 4.3 3.3 7.9 1.3 2.4 7.9 8.5 8.4 3.1 7.1 0.5 6.0 5.8 7.8 4.7 2.8 7.5 10.0 1.7 3.9 0.2 1.9 2.1 4.5 1.4 0.0 5.2 4.4 12.7 3.6 12.0 4.7 1.9 0.1 0.8 4.9 2.0 1.0 2.1 2.8 0.2 4.9 0.2 6.5 0.3 14.5 0.8 3.0 3.1 3.2 4.2 9.2 2.8 5.1 1.0 3.2 4.9 4.2 5.0 7.7 2.4 2.9 0.7 13.9 0.2 3.3 0.3 0.0 0.0 0.3 0.1 0.5 0.8 0.2 0.1 0.3 1.5 0.5 0.3 0.2 1.1 0.0 0.0 0.0 0.1 4.5 4.7 4.0 8.6 4.6 5.2 5.4 5.8 5.0 4.6 5.5 4.6 8.3 6.4 8.9 31.6 1.6 5.2 8.7 18.1 2.8 11.8 5.3 6.6 14.3 8.6 23.3 9.2 47.9 1.9 0.3 0.8 19.6 15.6 148.5 136.3 15.8 7.0 0.0 0.0 29.1 4.9 0.5 8.1 0.0 17.0 0.0 13.4 9.3 2.7 1.4 21.9 15.0 0.9 18.3 0.8 3.1 65.2 7.5 1.4 7.2 4.7 0.0 12.3 0.0 12.1 11.5 6.4 1.3 9.8 0.1 3.1 0.2 35.9 167.4 69.1 13.1 14.3 10.3 146.3 24.9 1.0 4.0 0.3 1.3 9.6 1.7 5.8 NPHP3 "CFAP31, FLJ30691, FLJ36696, KIAA2000, MKS7, NPH3, SLSN3" ENSG00000113971 "Nephrocystin 3" Q7Z494 3 132680609-132722414 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Ciliopathy, Disease variant, Meckel syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009150 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "HPA009150: AB_1078086" "unprognostic (1.02e-2)" "unprognostic (1.22e-1)" "unprognostic (1.56e-2)" "unprognostic (2.79e-1)" "unprognostic (2.22e-1)" "unprognostic (8.24e-3)" "unprognostic (2.36e-5)" "unprognostic (8.02e-3)" "unprognostic (6.51e-2)" "unprognostic (1.96e-2)" "unprognostic (9.42e-3)" "unprognostic (2.92e-2)" "prognostic unfavorable (8.28e-9)" "unprognostic (2.61e-2)" "unprognostic (2.51e-1)" "unprognostic (1.89e-1)" "unprognostic (1.40e-3)" 7.0 6.0 3.7 4.1 5.6 2.8 7.6 4.0 4.5 9.2 4.4 5.5 3.3 12.9 10.8 4.0 8.1 7.3 5.6 3.5 5.6 4.4 2.9 7.2 5.0 5.6 5.0 15.9 4.5 3.6 3.6 7.4 5.4 6.8 4.1 3.1 5.3 6.0 3.7 8.0 4.1 7.8 4.2 6.2 4.0 3.4 5.2 3.7 6.4 5.2 2.8 5.3 5.4 7.9 4.7 2.5 12.2 8.3 9.0 15.1 5.6 13.9 11.3 6.3 7.6 3.6 2.1 0.6 6.0 13.9 5.4 4.2 5.1 6.3 7.2 2.6 3.5 3.8 2.9 4.0 9.1 0.7 4.1 12.2 3.8 7.2 10.2 13.5 9.5 2.9 1.8 3.8 18.0 4.4 0.6 4.6 5.9 3.0 3.8 1.5 11.3 5.2 7.9 3.2 0.3 9.3 9.1 2.5 10.5 10.5 3.9 2.2 11.5 9.6 6.2 11.7 5.8 3.1 1.2 1.2 10.7 1.1 9.1 0.0 0.1 0.1 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.5 0.3 0.1 0.5 0.0 0.7 0.2 0.3 0.0 3.7 5.6 4.0 4.5 3.5 5.6 5.6 5.0 5.4 4.2 5.2 7.9 25.5 28.9 18.6 0.0 12.4 19.1 15.9 10.5 7.4 20.8 21.5 27.6 20.9 12.8 8.9 16.5 56.3 18.7 13.5 9.4 0.0 6.8 2.4 14.0 20.1 24.7 12.7 7.4 0.0 4.9 11.7 25.2 4.1 11.0 7.6 25.6 52.1 14.6 9.7 26.9 0.0 11.6 4.1 18.5 17.2 4.3 60.0 9.8 14.2 0.0 13.2 13.2 10.3 0.0 0.0 8.1 5.4 40.3 5.6 15.8 14.8 5.2 14.3 34.1 32.9 26.6 20.6 14.1 5.5 6.9 18.8 9.2 14.0 15.1 13.4 9.1 NPHP4 "KIAA0673, POC10, SLSN4" ENSG00000131697 "Nephrocystin 4" O75161 1 5862811-5992473 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 24.2;Cone photoreceptor cells: 33.3;Excitatory neurons: 47.1;Inhibitory neurons: 30.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 2.7;hippocampal formation: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063852, HPA065526" Approved Approved "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "Nuclear bodies, Vesicles" "HPA063852: , HPA065526: AB_2685505" "unprognostic (1.82e-1)" "unprognostic (1.57e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (5.83e-2)" "unprognostic (2.53e-2)" "unprognostic (1.08e-2)" "unprognostic (1.95e-1)" "unprognostic (2.52e-1)" "unprognostic (1.23e-2)" "unprognostic (7.49e-3)" "unprognostic (9.00e-2)" "unprognostic (1.75e-2)" "unprognostic (2.96e-2)" "unprognostic (1.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" 2.7 2.2 1.0 2.3 0.8 3.7 2.7 0.0 2.7 2.9 2.5 2.2 2.1 2.8 2.3 2.0 7.9 2.1 1.9 3.1 0.0 2.2 1.3 3.0 2.3 0.0 0.0 2.9 2.4 2.7 7.8 1.6 0.0 2.2 1.2 2.4 2.2 2.3 2.2 4.9 2.1 2.2 0.0 2.2 2.0 5.3 0.0 2.5 6.7 1.9 1.1 2.1 2.5 0.0 7.8 4.8 5.4 4.3 4.7 6.8 4.1 3.9 3.9 5.3 4.2 4.1 6.5 4.0 9.6 4.6 3.6 7.4 2.7 6.6 2.7 5.1 7.3 3.4 8.1 4.1 3.7 6.5 5.1 5.6 3.2 6.3 3.9 3.4 3.8 9.4 6.2 4.1 2.4 5.9 8.3 7.1 1.0 4.0 5.5 7.1 3.4 6.5 2.6 1.0 17.0 5.5 6.1 4.5 6.5 2.3 6.0 7.2 3.7 7.6 3.2 13.0 4.8 5.0 7.0 4.2 3.4 8.3 2.0 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 1.0 0.8 0.0 2.7 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 1.1 24.2 1.3 4.0 1.2 1.8 3.4 7.3 3.0 3.6 3.1 4.3 3.9 3.7 33.3 0.6 2.2 2.1 1.9 1.6 2.0 10.2 3.3 2.9 3.6 3.2 47.1 1.8 0.5 3.5 4.1 3.0 0.0 4.0 1.8 1.5 2.0 5.0 30.8 2.2 2.0 3.5 3.7 1.4 4.1 2.4 10.6 14.0 1.8 6.3 2.1 10.6 17.3 2.1 2.2 2.2 2.6 1.8 1.1 1.9 10.9 18.2 6.6 1.6 2.7 11.6 6.5 1.9 5.3 1.1 1.7 4.0 1.7 1.1 NPR2 "AMDM, ANPb, ANPRB, GUCY2B, NPRB" ENSG00000159899 "Natriuretic peptide receptor 2" P20594 9 35791591-35809732 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Osteogenesis" "Lyase, Receptor" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 35.6;Excitatory neurons: 69.1;Inhibitory neurons: 68.9;Microglial cells: 34.7;Oligodendrocyte precursor cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 30.9;ASC TERT1: 21.1;BJ hTERT+: 20.2;HHSteC: 20.1;HSkMC: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.93e-2)" "unprognostic (8.22e-3)" "unprognostic (9.25e-3)" "unprognostic (3.59e-2)" "unprognostic (6.13e-2)" "unprognostic (2.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.40e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-1)" "unprognostic (3.99e-2)" "unprognostic (6.99e-3)" "unprognostic (7.10e-2)" "unprognostic (3.24e-1)" "unprognostic (7.86e-2)" 12.4 8.2 9.3 1.7 9.4 0.3 10.3 14.4 9.9 25.7 7.7 15.6 1.8 20.5 8.7 3.2 15.1 3.2 12.8 9.1 11.4 6.7 8.6 9.1 2.3 11.8 9.4 9.4 3.2 1.3 13.8 4.7 11.5 10.9 2.8 4.1 5.3 6.5 10.8 8.3 7.5 9.9 8.2 4.9 7.8 4.8 10.7 2.2 6.0 8.6 1.7 12.1 14.7 7.9 0.0 2.9 2.2 0.0 30.9 21.1 1.9 9.3 20.2 7.0 6.4 4.5 4.3 1.8 3.0 17.9 12.8 1.2 3.6 0.2 6.1 2.2 1.0 1.8 4.3 3.4 20.1 0.4 0.0 23.8 1.8 8.9 0.6 7.6 12.7 2.5 0.7 0.2 13.4 1.0 0.5 0.8 3.5 1.0 3.7 2.4 0.2 0.5 1.8 1.4 1.1 0.7 0.4 0.1 0.6 3.8 0.2 0.0 8.2 8.5 7.8 3.2 1.2 0.5 0.6 4.8 10.4 0.6 5.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 9.3 9.4 14.4 9.9 9.1 11.4 11.8 9.4 11.5 8.2 10.7 7.9 2.7 3.2 3.4 35.6 0.0 1.1 0.6 0.6 1.2 5.1 0.7 1.4 0.7 1.5 0.3 0.0 2.1 0.4 0.5 0.7 0.0 0.6 0.3 1.4 9.2 4.4 0.0 0.0 69.1 0.8 0.2 7.2 0.5 2.0 1.3 9.6 6.1 4.5 0.4 3.3 68.9 0.7 0.0 0.3 2.1 0.3 9.3 0.3 0.0 34.7 0.0 6.8 0.0 51.8 16.3 0.6 3.6 7.9 0.2 2.7 0.2 0.6 1.1 2.2 0.0 5.1 3.4 4.5 3.1 0.1 1.6 0.3 0.7 0.8 1.1 0.4 NR2F2 "ARP1, COUP-TFII, COUPTF2, COUPTFB, NF-E3, SVP40, TFCOUP2" ENSG00000185551 "Nuclear receptor subfamily 2 group F member 2" P24468 15 96325938-96340263 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 292.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 542.2;Hepatic stellate cells: 395.5;Leydig cells: 510.4;Peritubular cells: 610.5;Sertoli cells: 486.4;Smooth muscle cells: 385.7;Theca cells: 572.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058974 Approved Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA058974: AB_2732629" "unprognostic (9.28e-2)" "unprognostic (2.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.42e-2)" "unprognostic (8.96e-2)" "unprognostic (5.44e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (2.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.89e-1)" "unprognostic (9.19e-2)" "unprognostic (5.14e-2)" "unprognostic (5.96e-2)" "unprognostic (1.72e-2)" "unprognostic (7.47e-2)" "unprognostic (1.28e-2)" 95.5 43.1 32.7 18.8 19.2 0.1 59.7 15.0 19.6 128.6 23.5 52.6 21.5 120.9 61.8 22.1 101.5 65.7 44.4 20.0 24.8 79.8 32.1 56.8 42.4 16.2 21.9 292.4 20.0 30.7 20.3 74.7 18.2 60.6 26.7 2.5 22.9 126.4 33.1 24.1 32.1 81.8 12.5 106.2 82.3 26.7 49.3 7.8 46.2 31.5 15.1 46.3 74.5 10.7 154.7 39.1 125.6 78.5 249.1 85.5 41.9 109.1 83.2 111.1 94.3 134.8 153.4 0.1 86.8 55.2 44.1 90.4 22.3 78.3 138.8 0.5 86.5 49.9 48.7 24.6 69.5 38.7 18.0 61.3 26.5 92.5 19.8 130.5 207.3 0.1 135.3 0.4 71.2 105.5 0.1 27.6 1.2 59.6 52.7 0.1 30.9 0.2 244.7 165.7 15.8 0.2 12.3 3.7 17.5 55.0 61.1 2.8 215.3 119.9 39.7 28.3 38.8 0.1 0.4 0.4 67.0 18.9 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 19.2 15.0 19.6 20.0 24.8 16.2 21.9 18.2 12.5 49.3 10.7 133.4 28.9 18.1 0.7 1.1 14.4 24.9 71.7 39.3 7.5 51.9 50.8 46.4 203.0 34.6 62.5 25.0 126.2 2.0 35.7 46.9 22.0 3.2 70.9 542.2 166.1 26.4 5.3 0.1 10.9 50.3 125.8 80.0 68.9 0.0 41.5 395.5 51.6 10.3 3.3 24.8 35.5 32.6 12.2 20.1 22.9 510.4 5.0 26.6 36.5 0.6 30.2 0.0 0.0 0.5 15.6 23.9 610.5 2.8 22.3 14.3 65.5 37.3 13.8 486.4 27.8 385.7 6.4 7.9 20.5 10.4 35.3 5.8 572.5 27.1 21.3 NRAS N-ras ENSG00000213281 "NRAS proto-oncogene, GTPase" P01111 1 114704469-114716771 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010157, HPA049830, CAB079912" Uncertain Supported "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010157: AB_632073, CAB079912: AB_2784586, HPA049830: AB_2680903" "unprognostic (4.75e-2)" "unprognostic (2.81e-1)" "unprognostic (1.09e-3)" "unprognostic (2.11e-2)" "unprognostic (8.59e-3)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-7)" "unprognostic (7.76e-3)" "unprognostic (1.57e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (6.60e-3)" "prognostic unfavorable (7.87e-4)" "unprognostic (2.68e-1)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (3.33e-2)" 19.0 9.1 10.3 25.7 11.2 58.5 18.0 11.5 12.3 12.5 8.6 27.8 21.5 12.4 7.8 20.7 10.3 17.2 8.3 10.2 12.2 20.9 24.9 18.5 30.4 12.3 12.1 9.6 11.4 9.0 4.3 28.3 12.3 11.4 26.6 6.6 10.9 7.1 7.7 19.8 22.5 14.1 11.7 18.6 21.8 9.6 11.4 39.0 16.1 7.8 29.7 22.2 8.6 13.4 93.7 24.9 65.2 24.9 26.4 56.3 46.5 43.5 48.4 79.5 89.0 50.4 33.9 70.4 56.3 58.9 55.4 26.0 88.2 70.6 113.4 96.5 34.2 47.8 34.5 60.2 52.3 120.0 71.0 51.1 56.1 91.5 66.2 25.0 102.8 54.6 77.3 78.5 71.0 248.9 83.5 46.4 111.0 30.2 17.9 62.9 116.0 44.1 70.6 49.5 39.4 59.0 44.7 36.4 107.1 75.4 31.9 96.2 79.2 43.3 82.2 81.5 90.3 137.7 101.6 81.6 86.4 64.6 159.0 38.7 12.8 12.6 11.7 19.2 10.5 12.8 9.3 11.6 12.6 10.5 9.9 12.9 3.4 15.5 17.6 9.6 13.4 13.1 10.3 11.2 11.5 12.3 10.2 12.2 12.3 12.1 12.3 11.7 11.4 13.4 22.7 16.0 16.5 8.1 25.9 30.7 31.2 23.1 15.4 5.2 18.5 13.6 5.6 18.6 19.3 22.0 8.4 22.4 27.7 49.2 13.7 34.1 3.9 22.9 24.7 29.2 24.6 31.6 5.8 31.5 50.4 16.1 29.0 38.0 31.1 22.2 33.2 29.7 49.2 5.0 5.2 28.1 30.5 44.9 30.7 5.9 8.1 30.4 23.2 9.4 41.6 7.8 22.6 5.0 8.1 51.4 32.9 6.4 39.6 30.6 28.1 39.4 23.1 3.3 6.6 12.8 15.3 7.3 15.4 24.6 36.2 31.2 21.9 13.8 28.8 40.2 NRIP1 RIP140 ENSG00000180530 "Nuclear receptor interacting protein 1" P48552 21 14961235-15065936 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 219.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 92.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029785, HPA046571, HPA060036" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 14: REH - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" Cytosol "HPA029785: , HPA046571: AB_2679704, HPA060036: AB_2684193" "unprognostic (5.60e-2)" "unprognostic (1.87e-1)" "unprognostic (5.20e-3)" "unprognostic (4.64e-3)" "unprognostic (7.98e-2)" "unprognostic (2.59e-2)" "unprognostic (2.74e-1)" "unprognostic (2.75e-3)" "unprognostic (8.94e-3)" "unprognostic (1.55e-1)" "unprognostic (2.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.80e-2)" "unprognostic (6.53e-2)" "unprognostic (1.07e-1)" "unprognostic (2.72e-1)" "unprognostic (2.80e-1)" 30.4 10.2 5.8 10.2 5.2 26.4 14.2 14.9 6.9 24.7 6.5 18.2 16.8 18.2 13.4 9.4 21.4 10.3 5.4 6.4 8.1 15.9 26.9 8.9 8.7 4.8 4.5 13.3 14.4 7.4 3.2 14.6 5.3 10.3 18.1 31.8 6.1 8.4 22.3 4.1 18.3 20.1 6.4 13.1 8.9 8.1 6.7 17.0 5.6 23.8 7.2 14.1 8.4 8.3 22.1 43.5 34.6 0.0 17.4 11.3 12.6 26.1 11.7 16.0 12.5 8.7 17.3 0.1 14.5 23.3 7.9 11.0 2.2 15.6 33.9 0.0 10.0 33.4 15.3 27.2 10.5 16.7 6.7 14.1 21.3 17.6 20.5 17.8 12.6 4.8 24.1 17.4 11.4 11.8 7.8 0.1 14.5 8.8 13.9 92.4 28.0 0.8 9.8 35.8 3.2 0.1 21.7 11.3 8.8 27.7 27.2 12.9 22.0 13.7 9.1 21.4 10.8 8.5 0.2 0.1 29.0 0.0 6.8 0.0 0.4 0.2 0.3 0.2 1.8 0.3 0.3 0.4 0.6 1.0 0.5 0.2 0.1 0.5 0.5 0.6 0.2 0.2 5.8 5.2 14.9 6.9 6.4 8.1 4.8 4.5 5.3 6.4 6.7 8.3 33.2 48.1 37.6 60.7 27.4 18.6 122.6 16.2 22.8 33.9 52.9 26.8 18.3 21.5 40.9 29.5 50.1 16.4 20.7 50.1 9.8 23.0 15.8 60.9 99.1 43.0 37.7 24.2 123.7 27.6 120.8 42.3 26.5 130.9 31.5 94.0 27.1 44.7 45.7 21.9 95.0 41.6 18.3 50.4 21.9 19.3 37.6 57.9 8.8 219.2 40.4 56.2 27.8 102.1 78.2 31.4 42.6 27.1 10.1 49.5 43.0 36.5 15.9 63.1 32.9 112.1 38.6 12.1 6.3 23.1 18.8 14.1 19.9 71.0 47.7 99.8 NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918503-51225575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Mental retardation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 145.0" "Group enriched" "Detected in many" 5 "Astrocytes: 4025.1;Excitatory neurons: 3206.3;Inhibitory neurons: 2116.2;Oligodendrocyte precursor cells: 4897.8" "Cancer enriched" "Detected in single" 8 "glioma: 3.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071400 Supported "Plasma membrane" "Intracellular and membrane" NA NA 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA071400: AB_2732180" "unprognostic (7.01e-2)" "unprognostic (9.96e-2)" "unprognostic (7.68e-2)" "unprognostic (1.74e-4)" "unprognostic (2.46e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (6.37e-4)" "unprognostic (2.85e-2)" "unprognostic (6.68e-7)" "unprognostic (3.40e-2)" "unprognostic (1.75e-1)" "unprognostic (5.57e-2)" "unprognostic (1.99e-3)" 1.1 2.0 40.9 1.1 60.9 0.3 0.8 145.0 74.4 2.2 0.0 11.3 0.9 1.1 3.0 2.0 0.8 1.2 5.2 62.7 16.8 0.4 0.5 0.4 0.3 0.0 2.2 0.9 1.4 0.0 6.0 0.0 7.2 2.8 2.6 7.2 2.4 8.4 0.2 0.9 2.6 1.0 4.7 0.2 2.3 5.6 15.7 1.2 0.6 0.8 0.2 2.3 3.1 22.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 31.3 1.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 3.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 40.9 60.9 145.0 74.4 62.7 16.8 0.0 2.2 7.2 4.7 15.7 22.0 0.1 0.0 0.0 4025.1 0.0 0.0 0.3 0.0 3.4 116.0 3.1 3.7 19.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.1 201.6 0.1 2.8 1.0 1.8 0.0 3206.3 0.0 0.0 2.3 0.0 0.1 0.0 0.2 3.3 0.2 0.1 77.4 2116.2 0.0 0.0 0.0 0.6 103.4 2.5 0.6 1.8 174.3 0.0 22.7 0.0 4897.8 678.0 0.2 0.0 0.7 1.4 0.5 0.0 0.2 0.0 9.7 0.0 2.5 1.3 13.3 5.8 0.6 0.1 0.3 0.1 0.1 0.0 0.1 NSD1 "ARA267, FLJ22263, KMT3B, STO" ENSG00000165671 "Nuclear receptor binding SET domain protein 1" Q96L73 5 177133025-177300213 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048431, HPA070333, HPA073705" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "HPA048431: AB_2680388, HPA070333: AB_2686255, HPA073705: AB_2732239" "unprognostic (3.48e-2)" "unprognostic (7.46e-2)" "unprognostic (7.14e-3)" "unprognostic (2.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.68e-3)" "unprognostic (8.04e-2)" "unprognostic (1.48e-1)" "unprognostic (2.09e-1)" "unprognostic (7.77e-3)" "unprognostic (3.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.51e-2)" "unprognostic (7.32e-2)" 8.7 7.2 8.9 12.0 13.4 21.2 10.9 26.2 10.4 11.1 9.8 10.1 8.4 11.5 10.3 11.4 10.1 8.0 9.1 7.7 10.0 10.6 6.6 9.2 13.7 9.7 10.8 12.3 11.3 12.8 9.0 10.7 12.2 9.3 10.8 11.9 10.4 9.6 13.6 12.0 9.4 12.0 6.6 11.3 8.9 23.2 12.0 20.2 15.5 11.5 14.7 9.3 7.9 17.5 20.5 25.9 26.0 22.8 12.5 16.1 0.9 18.2 17.9 24.6 22.8 5.7 16.6 41.7 19.9 24.8 22.7 17.0 41.9 40.0 29.7 72.9 25.9 18.6 29.5 0.2 20.7 40.4 21.2 15.2 23.6 29.4 27.3 17.5 36.4 26.0 25.9 14.3 25.2 42.3 28.3 13.1 28.5 13.7 22.5 31.0 3.4 12.9 15.9 24.4 31.6 21.9 46.7 20.1 13.8 24.1 20.2 33.0 27.4 17.1 25.0 11.0 22.6 16.7 15.7 29.5 9.9 19.3 18.7 14.7 9.0 10.5 7.2 6.1 6.0 8.5 6.1 5.0 7.2 10.3 7.5 6.0 18.6 11.3 12.2 9.4 6.4 3.4 8.9 13.4 26.2 10.4 7.7 10.0 9.7 10.8 12.2 6.6 12.0 17.5 37.4 22.4 31.4 84.9 71.7 17.0 32.8 27.2 34.1 94.4 29.8 25.7 44.5 34.3 35.0 55.2 150.1 43.6 66.1 19.7 17.6 27.8 31.9 27.1 65.7 36.4 41.9 48.3 107.0 21.2 23.7 32.7 41.8 41.9 41.7 64.0 33.5 19.9 27.7 89.2 110.3 25.6 12.2 36.8 25.7 50.3 51.0 47.1 16.0 115.2 75.0 29.2 95.8 140.8 157.5 23.7 31.0 33.1 55.8 29.4 33.6 19.2 17.3 112.3 52.6 42.9 36.1 83.7 62.1 41.8 20.6 35.4 62.0 55.9 28.2 30.0 NSDHL "H105e3, SDR31E1, XAP104" ENSG00000147383 "NAD(P) dependent steroid dehydrogenase-like" Q15738 X 152830967-152869729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 53.0;Hepatocytes: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000248, HPA000571" Enhanced Enhanced "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "Lipid droplets" "HPA000248: AB_1079507, HPA000571: AB_1079506" "unprognostic (1.84e-1)" "prognostic favorable (5.65e-4)" "unprognostic (2.66e-1)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.03e-1)" "unprognostic (5.70e-2)" "unprognostic (4.32e-2)" "unprognostic (5.62e-2)" "unprognostic (2.63e-1)" "prognostic favorable (6.09e-5)" "unprognostic (3.53e-2)" "unprognostic (1.36e-1)" "unprognostic (3.91e-2)" "unprognostic (4.79e-2)" 24.0 38.8 13.2 10.2 12.6 8.9 20.2 14.2 13.3 20.3 13.7 13.9 17.6 13.6 44.5 51.7 14.9 7.9 22.4 13.7 14.3 14.9 50.4 12.9 9.1 16.8 15.4 10.3 10.6 12.9 8.8 10.3 18.5 14.8 13.5 10.4 16.7 21.3 10.1 22.6 24.2 12.5 13.4 9.5 13.8 8.9 15.2 9.9 13.3 10.9 18.1 12.1 24.1 15.1 135.6 48.9 65.5 33.8 54.9 41.5 36.2 26.3 35.2 46.9 59.3 68.5 71.7 67.0 86.0 35.9 174.2 67.6 85.5 122.1 41.3 22.0 49.5 27.9 44.7 70.3 39.8 27.6 21.1 51.1 46.3 92.2 23.0 20.2 44.2 28.7 46.4 29.1 36.1 60.1 27.3 35.8 26.0 67.4 58.1 19.9 47.4 54.6 98.9 55.7 23.4 26.5 23.4 34.6 28.4 44.9 23.1 35.0 38.7 21.6 35.4 52.3 51.0 40.9 29.4 114.9 40.0 42.4 20.8 21.0 19.6 18.7 16.3 18.7 16.4 19.1 16.1 14.1 19.4 15.1 11.6 12.7 2.2 19.7 14.2 17.4 20.4 15.2 13.2 12.6 14.2 13.3 13.7 14.3 16.8 15.4 18.5 13.4 15.2 15.1 7.1 12.8 16.7 5.9 6.3 10.8 12.8 53.0 10.8 4.3 11.7 6.1 25.0 15.7 29.0 12.9 0.0 21.5 6.1 9.6 9.8 20.1 13.3 15.5 6.6 9.2 6.0 13.0 2.2 20.3 22.0 9.0 8.2 15.5 8.2 14.0 7.5 55.0 18.6 1.7 2.2 10.2 26.4 8.7 9.6 8.0 8.4 7.9 5.4 1.0 11.0 10.6 7.2 2.5 5.7 21.4 11.9 9.1 11.3 10.4 25.2 16.5 25.4 6.2 0.0 5.9 12.5 3.7 7.8 19.4 12.1 18.6 5.3 25.1 11.2 16.4 NSMCE2 "C8orf36, FLJ32440, MMS21, NSE2, ZMIZ7" ENSG00000156831 "NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase" Q96MF7 8 125091679-125367120 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis, Ubl conjugation pathway" Transferase "Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 136.1;Excitatory neurons: 150.1;Inhibitory neurons: 156.8;Microglial cells: 157.4;Oligodendrocyte precursor cells: 139.2;Oligodendrocytes: 386.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051614, HPA065734" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies" "HPA051614: AB_2681551, HPA065734: AB_2685549" "unprognostic (1.14e-3)" "unprognostic (1.29e-1)" "unprognostic (6.56e-2)" "unprognostic (1.22e-3)" "unprognostic (8.65e-2)" "unprognostic (8.89e-3)" "prognostic unfavorable (7.54e-4)" "unprognostic (3.99e-2)" "unprognostic (2.48e-1)" "unprognostic (1.00e-1)" "unprognostic (1.53e-2)" "unprognostic (1.33e-1)" "unprognostic (3.09e-2)" "unprognostic (1.17e-1)" "unprognostic (7.53e-2)" "unprognostic (2.61e-2)" "unprognostic (6.85e-2)" 19.9 18.1 11.0 14.1 12.8 30.3 23.7 12.4 12.9 17.0 13.4 18.6 12.5 15.8 18.6 17.0 13.4 15.9 23.8 11.2 12.4 18.9 17.8 14.2 21.7 12.2 11.9 19.0 12.8 17.8 11.2 19.6 12.6 13.2 17.5 16.7 16.0 13.9 33.6 15.8 12.3 16.1 11.8 14.5 16.6 15.5 12.7 26.0 18.1 27.2 26.1 20.7 14.7 16.1 43.0 36.3 42.3 26.9 32.7 48.9 20.5 33.5 62.5 58.2 67.0 23.4 39.9 53.2 38.5 32.0 42.9 31.1 33.4 28.2 58.8 60.0 32.4 75.4 20.0 34.1 47.7 22.8 22.1 36.5 38.4 33.6 43.6 38.8 53.2 27.5 44.1 34.2 51.4 74.3 58.9 20.9 9.3 48.4 48.0 33.3 29.4 48.6 35.5 32.1 28.0 29.7 40.1 119.2 56.3 24.9 50.9 25.9 33.3 22.3 62.9 27.8 48.3 45.1 86.6 67.6 35.4 43.4 35.3 12.9 23.9 69.4 22.0 21.7 24.3 25.0 23.1 24.8 24.4 25.5 23.7 25.9 11.3 22.0 23.3 14.2 37.6 24.5 11.0 12.8 12.4 12.9 11.2 12.4 12.2 11.9 12.6 11.8 12.7 16.1 21.8 9.6 13.1 136.1 22.0 23.8 36.3 39.1 21.1 23.8 23.3 24.8 20.1 21.5 26.0 11.0 16.7 34.2 20.3 16.2 27.4 33.1 28.0 26.4 19.7 23.0 13.8 36.2 150.1 42.5 27.8 21.4 13.7 20.7 25.4 24.1 23.2 13.7 44.3 15.2 156.8 17.7 18.3 26.5 24.3 9.9 23.3 24.4 17.8 157.4 29.4 18.4 20.6 139.2 386.0 34.2 19.5 24.5 20.2 28.1 20.6 35.2 23.4 26.4 6.6 20.7 23.4 44.4 31.7 16.0 18.9 46.7 24.6 20.9 19.8 37.6 NUP107 NUP84 ENSG00000111581 "Nucleoporin 107" P57740 12 68686951-68745809 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031679 Uncertain "Nucleoplasm,Nuclear membrane,Centrosome" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear membrane, Centrosome" "HPA031679: AB_2673992" "unprognostic (2.89e-1)" "unprognostic (3.32e-1)" "unprognostic (4.10e-1)" "unprognostic (5.43e-2)" "unprognostic (1.60e-1)" "unprognostic (6.32e-2)" "prognostic unfavorable (3.12e-9)" "unprognostic (4.03e-2)" "unprognostic (1.23e-2)" "unprognostic (2.28e-1)" "unprognostic (1.17e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (1.28e-6)" "unprognostic (3.43e-2)" "unprognostic (2.05e-1)" "unprognostic (1.00e-1)" "unprognostic (1.96e-1)" 15.4 11.1 5.0 17.9 6.3 24.0 17.8 8.2 6.0 12.9 6.3 13.0 10.3 16.7 14.3 10.7 13.5 9.3 11.4 4.6 5.0 10.6 11.8 12.8 25.8 5.6 5.7 16.3 9.3 11.8 6.8 13.8 5.5 12.0 16.2 14.7 10.3 12.2 11.7 15.8 12.9 14.0 5.4 15.8 11.0 20.9 5.5 25.6 10.3 12.1 25.5 12.4 10.7 7.6 53.1 66.8 77.8 56.7 22.6 28.6 84.1 56.6 32.4 83.0 68.9 67.6 43.7 96.3 53.7 27.2 36.9 59.4 88.4 41.7 109.8 90.8 65.6 110.1 46.2 57.4 14.2 97.9 35.6 15.2 19.4 66.5 43.2 29.0 50.3 54.9 133.7 67.3 52.8 64.3 81.3 85.2 85.8 20.3 64.6 81.9 93.6 57.8 36.1 55.3 45.7 46.9 62.7 46.5 34.4 60.4 69.8 46.7 31.1 45.0 45.8 53.0 69.9 29.2 62.2 115.2 34.7 70.2 54.2 10.5 9.2 14.4 17.7 12.5 23.4 18.7 17.5 19.3 10.2 18.7 21.5 19.5 2.4 30.5 23.2 8.1 20.0 11.8 5.0 6.3 8.2 6.0 4.6 5.0 5.6 5.7 5.5 5.4 5.5 7.6 18.3 12.8 17.7 13.7 38.1 17.3 18.4 28.1 25.0 23.8 12.5 11.4 13.5 12.8 18.9 9.2 18.8 30.7 30.3 12.2 11.7 22.8 45.3 12.6 18.2 20.6 8.5 64.4 23.8 17.6 30.8 19.6 16.3 10.2 15.8 35.6 15.4 7.0 17.5 13.5 20.1 12.6 42.7 13.9 16.2 9.6 38.8 18.3 19.6 15.9 27.0 16.7 36.0 21.6 34.3 22.1 9.9 21.8 22.9 19.4 10.5 6.4 21.9 29.6 13.1 18.4 18.2 89.4 51.9 18.7 17.6 14.1 27.0 24.5 16.8 12.5 NUP133 FLJ10814 ENSG00000069248 "Nucleoporin 133" Q8WUM0 1 229440259-229508341 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059767 Approved Supported "Nuclear membrane" NA NA 6300 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 59: Non-specific - Transcription" "Nuclear membrane" "HPA059767: AB_2684123" "unprognostic (2.05e-2)" "unprognostic (3.54e-1)" "unprognostic (5.75e-3)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (1.17e-1)" "unprognostic (3.02e-2)" "unprognostic (2.20e-2)" "unprognostic (5.72e-2)" "unprognostic (2.21e-1)" "unprognostic (4.93e-2)" "unprognostic (3.48e-1)" "unprognostic (8.31e-2)" "unprognostic (2.22e-1)" "unprognostic (7.01e-2)" "unprognostic (4.26e-2)" "unprognostic (3.30e-2)" 12.3 10.7 9.2 11.2 10.8 12.6 15.8 13.1 11.9 11.7 7.5 11.2 8.6 14.4 11.2 10.6 13.9 8.6 15.2 9.2 9.2 12.2 10.1 10.8 14.3 9.5 9.0 16.5 10.0 17.9 9.9 15.1 9.8 11.7 11.4 19.1 10.0 11.8 17.9 13.4 9.6 13.2 10.1 11.6 9.8 13.0 8.9 16.8 13.8 14.3 15.4 11.1 10.4 14.5 30.6 24.3 37.0 19.2 26.0 27.8 71.9 24.8 25.1 36.0 32.4 28.8 29.4 44.1 20.9 24.8 16.1 39.4 51.8 26.3 38.4 26.8 64.2 26.7 23.6 21.8 20.9 54.8 20.8 21.8 19.4 25.9 30.8 25.0 30.5 37.1 61.2 20.6 28.6 13.7 40.8 23.4 55.6 42.7 21.8 39.1 38.5 43.6 20.3 26.6 31.7 39.3 36.9 22.9 27.6 18.0 35.7 42.8 26.8 16.3 19.9 28.5 37.3 19.7 26.1 46.8 18.6 31.2 34.6 5.5 5.7 4.4 5.6 5.7 7.0 5.8 5.9 6.2 7.1 4.4 5.9 6.3 1.9 5.5 10.2 4.0 5.9 5.2 9.2 10.8 13.1 11.9 9.2 9.2 9.5 9.0 9.8 10.1 8.9 14.5 10.4 9.6 18.9 26.4 19.9 9.1 6.8 10.1 13.6 16.5 9.9 8.5 21.2 14.3 10.7 14.7 8.4 21.4 11.5 4.4 5.9 8.3 1.5 10.9 8.7 10.3 10.2 21.7 48.9 8.5 13.8 13.8 15.8 8.4 7.6 17.1 11.7 12.0 9.8 16.8 44.1 7.5 8.2 13.6 8.6 3.7 12.5 10.8 7.2 25.3 13.4 12.4 5.2 28.1 60.2 7.0 4.9 12.0 19.0 6.7 4.7 7.9 13.1 12.3 0.0 16.3 10.7 12.6 18.2 14.6 10.7 18.3 13.6 11.8 9.0 6.6 NUP37 "FLJ22618, MGC5585" ENSG00000075188 "Nucleoporin 37" Q8NFH4 12 102073103-102120120 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056300, HPA073708" Supported Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA056300: AB_2683092, HPA073708: AB_2686629" "unprognostic (1.42e-3)" "unprognostic (5.39e-2)" "unprognostic (3.31e-2)" "unprognostic (1.03e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (6.72e-4)" "prognostic unfavorable (7.70e-6)" "unprognostic (2.48e-3)" "unprognostic (2.37e-3)" "unprognostic (7.77e-2)" "unprognostic (2.90e-3)" "unprognostic (1.67e-2)" "unprognostic (7.47e-2)" "unprognostic (5.55e-2)" "unprognostic (1.88e-1)" "unprognostic (3.06e-1)" "unprognostic (3.64e-1)" 11.3 14.2 4.1 17.1 4.4 22.7 19.5 5.1 7.8 12.8 2.4 20.1 13.0 11.9 21.5 18.9 19.0 10.9 17.6 4.8 4.5 15.2 13.0 11.6 28.1 3.5 2.8 12.1 8.7 17.4 5.9 16.9 3.4 13.7 23.8 10.9 11.7 13.8 17.5 13.4 14.9 17.7 2.4 12.0 12.9 15.1 4.3 25.7 16.4 15.5 33.5 17.7 9.6 6.3 105.5 74.5 64.2 29.6 51.7 68.4 144.6 64.8 61.0 99.8 68.0 97.4 55.5 70.1 45.4 50.9 68.9 76.2 113.5 101.2 124.4 98.5 65.2 75.6 37.2 86.4 66.0 107.5 22.8 53.4 43.5 78.3 57.3 66.7 83.3 91.2 135.5 25.8 93.9 71.6 79.9 87.9 63.4 96.8 117.2 51.9 92.0 52.8 79.0 76.1 33.6 24.0 49.8 52.7 50.3 72.1 90.7 61.7 27.2 35.7 39.4 51.0 91.1 38.5 78.9 119.4 41.9 86.1 61.8 67.8 24.0 28.3 21.4 29.3 23.2 31.2 25.7 21.9 30.2 28.2 23.0 26.1 7.0 23.9 24.9 25.3 45.4 22.5 4.1 4.4 5.1 7.8 4.8 4.5 3.5 2.8 3.4 2.4 4.3 6.3 12.3 6.4 14.3 8.8 22.6 11.3 20.9 63.8 17.1 8.0 10.5 11.7 9.5 14.3 28.2 16.5 8.4 68.1 17.7 9.1 25.4 24.0 2.9 21.6 17.6 17.2 6.0 38.7 5.8 20.0 92.3 19.9 12.2 11.8 7.6 21.2 13.6 10.0 35.6 3.3 7.3 16.0 22.4 15.2 8.4 6.3 19.6 13.5 7.2 5.6 20.5 18.9 13.4 11.1 12.6 17.2 10.6 18.8 34.1 10.7 11.5 24.6 39.3 20.1 19.7 8.6 18.3 49.0 42.4 25.5 9.5 40.2 18.8 31.9 26.5 16.8 NUP88 MGC8530 ENSG00000108559 "Nucleoporin 88" Q99567 17 5360963-5419676 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 146.0;Spermatocytes: 147.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002209, HPA021816" Approved Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB002209: AB_564128, HPA021816: AB_1854725" "unprognostic (3.46e-2)" "unprognostic (1.66e-2)" "unprognostic (1.04e-2)" "unprognostic (8.83e-2)" "unprognostic (1.05e-1)" "unprognostic (2.03e-1)" "unprognostic (3.38e-2)" "unprognostic (3.94e-1)" "unprognostic (4.72e-2)" "unprognostic (4.94e-2)" "unprognostic (2.04e-2)" "unprognostic (5.75e-3)" "unprognostic (1.49e-1)" "unprognostic (1.10e-1)" "unprognostic (9.03e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" 11.8 12.0 4.2 16.3 3.8 20.8 15.2 7.5 6.0 10.8 3.3 13.2 9.9 10.4 16.4 12.1 12.4 8.0 12.2 3.9 3.9 15.2 27.3 9.4 26.4 4.1 4.0 8.5 10.2 15.3 9.0 10.9 4.3 11.5 19.3 9.6 13.2 10.3 31.2 12.9 11.7 13.7 3.6 14.8 12.3 49.3 3.8 24.1 14.6 21.6 32.9 15.1 9.0 4.2 46.2 50.0 44.0 33.3 18.3 20.0 40.2 35.8 29.0 58.7 52.0 41.5 17.8 88.6 13.3 33.1 38.1 43.5 73.6 39.6 74.7 22.7 48.6 40.0 42.7 32.5 24.8 31.8 34.6 14.3 28.2 43.7 71.3 24.5 41.0 34.3 42.3 22.2 46.5 24.3 46.7 23.4 41.2 46.4 23.9 44.1 48.5 38.7 30.7 22.3 17.5 33.9 44.0 20.4 28.1 33.7 22.9 37.3 26.8 26.4 28.3 27.1 66.9 15.0 19.4 39.5 31.3 36.3 37.4 5.4 7.6 4.3 12.4 12.2 12.3 39.1 13.3 15.0 10.9 35.7 14.3 15.9 0.9 21.1 14.3 12.2 17.6 11.5 4.2 3.8 7.5 6.0 3.9 3.9 4.1 4.0 4.3 3.6 3.8 4.2 6.9 12.8 17.8 10.1 38.0 22.2 31.5 13.5 14.2 13.3 8.9 6.2 10.7 11.5 18.1 16.5 16.7 30.1 19.3 15.2 11.7 27.9 146.0 26.1 15.0 11.5 13.8 28.6 22.9 25.4 24.8 12.2 15.3 47.2 7.6 14.9 9.3 16.5 11.4 10.1 20.4 10.1 14.2 7.9 12.3 38.0 15.2 10.6 3.6 11.2 19.4 7.8 26.8 13.0 17.8 23.3 15.4 10.9 9.4 21.7 9.9 7.5 11.5 11.0 13.1 19.5 20.5 147.5 61.8 15.8 17.0 36.0 17.9 13.6 17.6 42.8 OBSL1 KIAA0657 ENSG00000124006 "Obscurin like cytoskeletal adaptor 1" O75147 2 219550728-219571859 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 337.3" "Group enriched" "Detected in many" 8 "Early spermatids: 1140.1;Late spermatids: 1994.5;Spermatocytes: 572.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.4;plasmacytoid DC: 1.3" "Group enriched" "Detected in many" 11 "dendritic cells: 1.3;granulocytes: 4.4" "Cell line enhanced" "Detected in many" "BEWO: 155.2;SK-BR-3: 150.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036404, HPA036405" Approved Approved Centrosome NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Centrosome "HPA036404: AB_10670437, HPA036405: AB_2675104" "unprognostic (2.36e-1)" "unprognostic (6.79e-2)" "unprognostic (3.86e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.27e-3)" "unprognostic (2.89e-2)" "unprognostic (9.89e-2)" "unprognostic (4.22e-3)" "unprognostic (1.25e-1)" "unprognostic (4.21e-3)" "unprognostic (7.00e-2)" "unprognostic (3.95e-2)" "unprognostic (3.62e-2)" "unprognostic (1.43e-1)" "unprognostic (3.15e-1)" "unprognostic (2.16e-1)" 52.3 117.5 25.0 9.7 24.3 3.1 53.5 24.4 32.2 74.6 34.4 44.6 9.4 78.0 22.5 17.7 84.6 28.8 90.8 26.1 27.9 110.1 43.9 38.6 9.6 30.3 29.1 337.3 120.6 49.5 74.9 45.8 24.8 63.1 5.4 14.9 62.9 44.2 64.1 38.3 22.5 20.9 25.2 31.7 48.0 40.5 29.7 6.9 148.9 30.2 4.6 41.2 36.7 22.3 34.2 22.7 40.9 85.8 27.7 20.4 155.2 25.3 36.8 31.5 29.0 20.0 52.2 0.2 51.6 34.7 30.5 34.4 31.9 19.0 6.5 0.3 56.2 74.3 23.0 102.1 20.9 1.9 0.3 55.3 15.4 7.3 12.1 56.1 3.4 0.1 31.3 0.7 22.7 84.6 0.1 21.3 97.8 9.7 23.1 37.5 36.3 0.2 57.4 31.9 18.1 61.3 28.6 150.9 59.2 102.8 14.0 63.9 8.6 33.3 35.6 10.6 10.0 0.2 0.2 0.3 19.5 0.2 33.7 4.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 1.3 0.0 0.0 25.0 24.3 24.4 32.2 26.1 27.9 30.3 29.1 24.8 25.2 29.7 22.3 10.4 9.6 20.4 45.7 1.1 8.4 22.8 11.7 19.9 35.8 27.0 38.7 52.4 27.1 10.0 53.3 2.1 64.7 2.5 1.5 52.8 15.9 1140.1 19.5 33.0 11.4 20.4 0.0 21.1 12.5 69.7 30.1 6.6 21.7 4.5 152.8 11.4 15.4 7.7 42.1 43.3 3.7 6.1 1.0 3.9 1994.5 77.0 3.4 14.2 9.4 0.7 87.0 0.0 23.1 3.1 7.6 2.0 74.1 0.1 8.8 7.1 20.3 7.8 11.6 13.1 29.9 27.0 572.7 57.0 4.3 6.7 86.5 1.4 114.0 3.3 10.2 ODC1 ODC ENSG00000115758 "Ornithine decarboxylase 1" P11926 2 10439968-10448327 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Polyamine biosynthesis" "Decarboxylase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 560.8;Late spermatids: 834.9;Prostatic glandular cells: 412.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001536, CAB035996" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "CAB035996: , HPA001536: AB_1079521" "unprognostic (2.33e-1)" "unprognostic (3.41e-1)" "unprognostic (7.25e-3)" "unprognostic (5.21e-3)" "unprognostic (4.22e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (3.06e-2)" "unprognostic (4.18e-2)" "unprognostic (6.27e-2)" "unprognostic (3.04e-1)" "unprognostic (6.65e-2)" "unprognostic (1.67e-3)" "unprognostic (1.18e-1)" "unprognostic (1.05e-1)" "unprognostic (2.26e-2)" "unprognostic (5.86e-2)" 47.2 23.2 31.0 69.3 31.5 172.9 33.0 30.5 32.2 33.5 48.5 64.8 32.4 66.0 49.2 29.4 56.3 43.7 55.9 29.9 33.0 132.2 92.1 52.4 111.0 32.4 33.0 54.8 61.8 99.6 92.5 20.0 30.6 91.1 72.0 46.2 27.0 55.1 163.3 29.2 41.6 71.2 34.1 42.9 51.5 133.3 34.0 77.1 58.5 73.5 149.1 113.6 26.9 35.7 166.8 130.6 177.1 211.4 31.1 92.4 410.1 234.6 114.9 216.3 99.9 697.3 75.4 870.2 114.6 143.6 208.6 30.2 549.1 265.5 261.2 334.0 231.5 398.1 212.2 429.9 250.8 680.1 91.8 62.5 70.5 490.1 608.3 111.4 176.3 237.6 674.2 274.3 121.7 109.0 680.1 267.3 324.9 228.3 418.8 478.5 556.0 586.3 130.9 119.5 246.6 209.9 293.6 88.8 121.8 135.7 60.0 300.5 124.7 174.4 362.6 227.9 511.7 128.0 416.1 780.8 156.7 443.6 109.9 0.0 1.5 3.0 2.9 2.9 3.3 14.8 4.1 4.8 3.4 15.0 2.8 4.5 0.5 1.4 1.8 12.2 4.4 3.2 31.0 31.5 30.5 32.2 29.9 33.0 32.4 33.0 30.6 34.1 34.0 35.7 78.2 44.8 161.4 7.5 228.9 58.0 123.7 48.8 19.4 36.8 53.2 68.3 55.1 81.5 33.9 40.5 31.3 1.5 188.1 77.7 72.4 50.6 560.8 90.9 66.2 52.2 271.0 111.3 7.5 27.6 70.0 63.2 204.4 127.6 58.9 103.8 14.6 50.3 46.8 6.7 4.1 234.1 22.4 32.1 22.4 834.9 15.5 191.8 23.2 8.4 22.1 126.3 37.0 4.5 2.4 28.6 64.5 11.3 287.4 412.4 31.6 154.1 21.9 77.4 0.0 223.0 79.9 186.5 75.8 52.2 87.5 3.4 133.0 30.2 180.5 142.2 OFD1 "71-7A, CXorf5, JBTS10, RP23" ENSG00000046651 "OFD1 centriole and centriolar satellite protein" O75665 X 13734745-13769357 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "plasmacytoid DC: 64.2" "Lineage enriched" "Detected in all" 4 "dendritic cells: 64.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031102, HPA031103, HPA031104" Approved Supported Microtubules NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" Microtubules "HPA031102: AB_10670836, HPA031103: AB_10602188, HPA031104: AB_10669655" "unprognostic (3.10e-3)" "prognostic favorable (9.62e-4)" "unprognostic (2.83e-1)" "unprognostic (2.68e-2)" "unprognostic (1.10e-1)" "unprognostic (7.42e-3)" "unprognostic (2.20e-3)" "unprognostic (3.03e-3)" "unprognostic (1.82e-2)" "unprognostic (1.43e-3)" "unprognostic (2.82e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (3.32e-2)" "unprognostic (3.90e-2)" "unprognostic (1.04e-2)" "prognostic favorable (2.76e-7)" 5.8 5.9 8.3 11.7 8.7 15.6 14.6 10.8 9.8 11.2 10.1 9.4 10.2 10.5 11.5 9.9 9.6 7.3 5.9 8.2 9.4 9.6 7.2 9.2 19.1 9.7 8.3 11.2 11.2 15.3 10.9 5.3 8.9 11.7 8.2 11.2 15.6 6.5 5.2 11.8 12.8 7.6 8.2 13.9 12.2 9.9 8.4 10.1 12.9 4.1 16.8 8.5 10.4 10.0 16.0 7.1 10.3 18.4 8.4 13.0 7.7 4.9 11.3 5.7 7.3 12.8 17.7 23.2 12.5 5.9 10.6 15.3 7.5 13.7 9.2 11.6 18.9 10.8 22.3 10.8 6.4 14.4 19.1 10.4 9.1 12.9 12.7 10.6 6.4 4.2 16.5 20.4 6.4 12.6 9.9 17.3 10.8 5.8 10.2 24.9 11.9 46.6 8.9 13.5 10.5 16.6 23.2 18.5 11.6 22.7 17.5 13.0 5.8 10.0 5.2 12.1 6.3 15.1 15.1 26.9 8.3 6.4 8.3 4.3 1.7 6.2 11.6 2.2 13.4 13.7 10.1 14.2 3.8 15.4 8.3 12.5 4.7 14.1 3.1 64.2 8.6 4.4 8.3 8.7 10.8 9.8 8.2 9.4 9.7 8.3 8.9 8.2 8.4 10.0 40.2 70.5 64.1 60.4 90.8 22.4 89.3 51.8 38.1 47.9 65.9 64.1 17.8 35.8 66.7 31.3 89.6 34.5 219.8 82.3 7.9 60.2 178.6 232.2 33.0 39.5 48.6 30.1 43.3 59.3 23.4 31.2 58.1 180.8 27.3 41.1 24.7 13.3 25.2 37.0 50.2 60.3 42.7 19.8 43.0 187.4 52.2 35.1 17.8 32.8 38.2 41.3 145.2 76.9 64.5 60.7 72.9 33.8 50.5 84.4 83.8 15.3 81.3 107.2 39.5 42.4 25.2 72.7 59.9 32.6 27.3 87.0 102.2 30.7 52.2 82.8 ORC1 "HSORC1, ORC1L, PARC1" ENSG00000085840 "Origin recognition complex subunit 1" Q13415 1 52372829-52404423 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 29.0;lymphoid tissue: 11.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.5;Early spermatids: 5.6;Erythroid cells: 14.1;Extravillous trophoblasts: 9.9;Plasma cells: 6.3;Spermatogonia: 6.5" "Cancer enhanced" "Detected in many" "testis cancer: 15.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "NK-cell: 3.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027439, HPA027450" Approved Supported Nucleoplasm NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027439: , HPA027450: AB_10602041" "unprognostic (3.28e-1)" "unprognostic (4.42e-3)" "prognostic favorable (1.74e-5)" "unprognostic (1.29e-2)" "unprognostic (7.29e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (3.22e-5)" "unprognostic (3.77e-3)" "prognostic unfavorable (3.69e-4)" "unprognostic (3.86e-2)" "unprognostic (2.70e-3)" "unprognostic (8.39e-2)" "unprognostic (1.25e-10)" "unprognostic (4.56e-3)" "unprognostic (1.05e-1)" "unprognostic (2.45e-1)" "unprognostic (1.57e-2)" 0.4 0.6 0.2 3.5 0.1 29.0 1.1 0.6 0.2 0.6 0.0 3.4 1.7 0.6 0.1 2.7 0.3 0.4 0.2 0.1 0.2 0.5 0.6 0.6 6.7 0.3 0.0 0.5 0.3 0.3 0.3 1.9 0.2 0.4 4.0 1.0 0.6 0.1 0.5 2.0 2.3 0.9 0.0 2.0 1.0 5.2 0.2 11.6 0.3 0.1 7.7 0.9 1.0 0.3 19.3 20.8 33.0 21.7 0.8 2.7 31.8 13.5 12.2 38.9 40.0 25.8 10.7 44.2 11.6 8.5 17.8 25.9 48.9 16.9 33.8 19.0 28.1 53.2 30.2 25.8 0.2 71.9 29.2 1.4 0.8 38.1 4.3 2.7 11.7 27.6 63.0 20.9 12.8 14.4 56.9 34.0 73.1 11.7 29.5 60.2 51.3 43.1 6.8 25.0 18.5 15.6 31.0 18.8 10.3 30.5 10.2 28.7 5.4 15.8 22.5 24.9 34.0 10.9 31.1 54.4 15.6 52.6 19.5 0.0 0.1 0.0 0.2 0.1 0.2 0.2 0.4 0.4 0.6 0.8 0.1 0.3 0.4 3.4 0.2 0.0 1.2 0.3 0.2 0.1 0.6 0.2 0.1 0.2 0.3 0.0 0.2 0.0 0.2 0.3 0.6 0.0 0.0 0.3 1.7 0.9 0.3 0.4 1.2 0.7 0.7 1.1 0.5 0.0 0.1 0.0 0.0 5.5 0.7 1.2 0.0 0.3 5.6 0.5 0.6 0.5 0.0 14.1 0.7 0.2 9.9 0.7 0.5 0.6 0.0 2.8 0.0 0.2 2.9 0.0 0.7 1.3 0.0 0.3 0.4 3.8 0.6 0.6 0.0 1.0 0.3 0.2 0.0 0.5 0.5 0.2 0.8 0.4 6.3 0.2 0.2 3.9 0.1 0.9 0.0 0.6 0.7 4.1 6.5 2.5 1.1 1.8 1.1 0.9 3.7 0.4 ORC4 "HsORC4, ORC4L, Orc4p" ENSG00000115947 "Origin recognition complex subunit 4" O43929 2 147930396-148021604 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015124, HPA064562" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli" "CAB015124: AB_2157883, HPA064562: AB_2685287" "unprognostic (5.04e-2)" "unprognostic (6.56e-2)" "unprognostic (4.51e-2)" "prognostic unfavorable (7.27e-4)" "unprognostic (8.28e-2)" "unprognostic (6.45e-2)" "prognostic unfavorable (4.98e-8)" "unprognostic (5.55e-2)" "unprognostic (8.00e-2)" "unprognostic (1.81e-2)" "unprognostic (4.92e-2)" "unprognostic (1.19e-1)" "prognostic favorable (4.10e-6)" "unprognostic (2.49e-1)" "unprognostic (1.34e-1)" "unprognostic (1.62e-1)" "unprognostic (1.95e-3)" 9.7 11.2 11.5 10.1 13.1 19.3 14.6 21.6 16.3 9.0 8.7 12.6 12.0 12.0 11.0 10.6 14.2 9.7 11.6 12.8 10.8 20.5 12.8 9.3 10.9 9.6 7.9 16.7 8.2 16.2 7.6 10.1 10.0 12.1 13.8 19.7 13.4 10.3 15.0 9.3 11.4 11.5 7.6 8.9 9.4 15.5 10.9 15.7 15.6 10.9 11.9 10.2 6.6 14.4 22.8 19.3 37.2 20.4 14.2 13.9 39.9 25.2 21.3 31.3 31.0 47.9 22.6 29.3 26.8 15.1 27.7 22.4 43.4 25.2 32.4 20.6 36.1 40.2 19.0 32.8 18.8 25.9 14.5 11.9 29.4 34.0 13.9 23.3 21.4 27.5 38.8 14.9 21.2 23.8 20.1 20.9 42.3 18.9 28.0 21.6 24.9 26.5 34.5 46.3 35.0 27.4 22.6 24.7 30.1 33.6 18.9 12.2 15.5 23.5 23.2 17.3 23.4 14.7 37.9 27.5 19.1 20.0 14.6 24.1 13.1 18.3 13.6 17.5 13.9 14.1 12.9 13.9 16.4 14.5 13.4 13.5 18.8 19.3 14.0 8.3 15.1 11.7 11.5 13.1 21.6 16.3 12.8 10.8 9.6 7.9 10.0 7.6 10.9 14.4 21.5 83.3 62.5 53.5 26.0 26.0 21.8 47.1 27.3 48.7 20.3 24.0 25.9 11.5 66.1 12.9 39.6 40.3 27.3 21.7 45.0 31.6 34.0 47.9 17.6 23.8 22.9 46.5 88.4 17.2 48.2 27.7 14.3 26.1 45.5 28.3 19.2 17.1 23.8 53.8 91.4 18.9 28.5 18.8 20.7 15.7 22.4 19.7 21.4 34.7 22.0 33.8 24.7 69.9 71.3 18.3 15.4 21.4 12.8 24.4 23.2 55.4 85.8 37.5 32.9 23.2 31.5 61.2 26.8 22.6 24.9 32.7 25.6 16.9 21.8 20.6 ORC6 ORC6L ENSG00000091651 "Origin recognition complex subunit 6" Q9Y5N6 16 46689643-46698394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;lymphoid tissue: 7.4;testis: 9.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 56.7;Spermatocytes: 102.6;Spermatogonia: 108.9;Theca cells: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016330, HPA072587" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" Yes No "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center" "CAB016330: AB_670295, HPA072587: AB_2686537" "unprognostic (3.47e-2)" "unprognostic (8.99e-3)" "unprognostic (2.92e-1)" "unprognostic (4.47e-2)" "unprognostic (2.27e-1)" "unprognostic (2.19e-2)" "unprognostic (3.15e-6)" "unprognostic (1.36e-2)" "prognostic unfavorable (3.53e-4)" "prognostic favorable (1.48e-4)" "unprognostic (1.50e-4)" "unprognostic (3.97e-2)" "unprognostic (3.90e-14)" "unprognostic (2.08e-1)" "unprognostic (4.24e-1)" "unprognostic (2.79e-1)" "unprognostic (5.98e-2)" 0.3 0.7 2.0 2.2 1.6 10.3 0.6 1.5 1.9 0.7 1.0 1.7 1.5 0.8 1.1 4.1 0.4 0.6 1.5 1.9 1.8 0.4 0.9 0.6 7.4 1.5 1.9 0.4 0.3 0.7 0.6 3.3 1.7 0.3 1.9 0.3 0.7 0.2 0.1 1.1 1.5 1.0 1.6 2.4 0.8 9.6 1.8 6.2 0.5 0.3 7.3 1.2 1.3 1.8 28.6 27.4 43.7 33.9 5.4 6.8 31.6 54.2 20.2 59.3 30.9 39.3 18.0 35.6 27.1 10.5 29.1 29.9 57.9 15.1 50.4 17.2 46.4 27.9 13.2 40.1 6.6 46.5 23.7 1.8 2.6 32.4 17.1 9.3 20.0 30.1 36.0 17.4 35.9 26.9 65.6 60.7 48.1 20.7 76.0 78.6 80.6 35.8 14.9 9.8 52.2 30.4 24.5 29.8 18.1 34.9 15.6 37.9 11.6 53.7 34.6 33.6 51.8 12.5 18.9 123.2 22.2 29.5 40.1 0.0 0.3 0.3 0.9 0.7 0.4 0.7 0.5 0.5 0.6 1.4 0.8 0.3 0.0 0.8 0.8 1.0 1.2 0.7 2.0 1.6 1.5 1.9 1.9 1.8 1.5 1.9 1.7 1.6 1.8 1.8 1.6 3.2 14.5 1.0 8.8 6.6 2.2 3.6 8.6 6.6 4.1 5.8 3.7 1.5 6.3 5.5 4.2 39.3 6.0 9.5 1.9 2.5 13.2 6.5 7.5 4.3 1.8 45.4 6.3 0.7 40.9 8.0 7.1 9.4 1.3 56.7 0.7 9.9 15.7 11.8 2.7 12.4 6.1 3.8 11.9 8.9 2.8 7.7 33.8 2.8 1.2 2.5 2.1 0.0 2.0 2.1 1.4 3.4 18.5 2.6 2.3 1.0 10.7 10.2 0.0 5.1 7.3 102.6 108.9 16.9 6.0 10.9 7.5 47.5 14.4 2.7 OSGEP "GCPL1, KAE1, OSGEP1, PRSMG1, TCS3" ENSG00000092094 "O-sialoglycoprotein endopeptidase" Q9NPF4 14 20446401-20455089 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039751 Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 52: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 57: B-cells - Immune response" Nucleoplasm "Plasma membrane" "HPA039751: AB_10794754" "prognostic favorable (1.48e-4)" "unprognostic (4.15e-3)" "unprognostic (1.29e-1)" "unprognostic (4.33e-3)" "unprognostic (1.54e-2)" "unprognostic (3.95e-2)" "unprognostic (5.54e-3)" "unprognostic (2.80e-3)" "unprognostic (2.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.35e-3)" "unprognostic (1.22e-1)" "prognostic unfavorable (4.64e-6)" "unprognostic (4.83e-2)" "unprognostic (1.86e-2)" "unprognostic (2.53e-2)" "unprognostic (9.91e-2)" 5.7 6.3 6.1 3.8 6.2 6.1 7.0 6.4 7.3 6.8 6.8 7.6 3.8 6.4 8.5 6.0 6.1 6.6 8.1 6.0 6.3 5.8 11.1 6.2 9.3 6.4 6.1 5.3 5.6 7.4 5.2 6.7 6.4 4.9 7.0 4.1 5.3 8.3 10.5 4.7 6.2 5.6 6.5 8.4 6.4 2.4 6.3 9.9 7.6 9.9 10.1 8.2 4.9 6.9 10.3 17.2 5.6 16.2 9.9 6.6 17.6 8.0 11.3 21.1 20.1 21.5 12.3 21.1 10.3 11.0 9.0 8.6 17.9 17.6 14.1 16.8 19.1 14.8 12.2 32.1 7.4 24.3 19.7 5.3 5.2 26.1 14.0 4.6 14.3 18.8 14.0 12.1 17.6 21.0 25.0 11.8 9.1 31.5 31.8 35.3 10.3 12.4 12.8 11.7 21.3 4.2 15.4 16.0 11.9 3.3 9.7 23.7 6.1 8.7 21.2 11.3 10.7 3.4 18.0 31.7 5.0 36.1 11.0 9.3 29.2 38.5 18.8 27.9 17.4 28.7 19.7 17.2 44.5 38.1 15.9 17.4 13.8 20.9 23.3 16.9 19.2 24.6 6.1 6.2 6.4 7.3 6.0 6.3 6.4 6.1 6.4 6.5 6.3 6.9 27.1 35.3 34.9 16.3 46.0 11.5 20.9 26.2 14.2 37.8 24.0 25.1 17.2 15.7 29.1 23.9 37.5 66.3 31.8 22.5 35.2 24.7 3.1 19.2 18.3 24.1 26.9 19.6 23.0 29.8 47.0 23.4 28.1 16.3 25.9 24.6 25.7 19.3 65.8 10.1 24.1 24.2 22.4 30.7 32.8 3.0 19.3 34.2 21.4 7.5 28.4 31.0 32.0 16.6 17.0 20.0 30.6 21.4 26.2 10.9 42.2 39.7 25.5 51.5 13.1 24.6 23.9 7.8 16.9 22.0 11.5 46.1 26.8 37.3 31.6 17.4 OSTM1 "GL, HSPC019" ENSG00000081087 "Osteoclastogenesis associated transmembrane protein 1" Q86WC4 6 108041409-108165854 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Osteopetrosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Melanocytes: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010851 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No 210000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Vesicles" "HPA010851: AB_1079533" "prognostic unfavorable (4.36e-4)" "unprognostic (4.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" "unprognostic (1.72e-3)" "prognostic unfavorable (4.26e-4)" "unprognostic (9.40e-2)" "unprognostic (2.56e-1)" "unprognostic (2.25e-1)" "unprognostic (4.06e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (1.34e-6)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.32e-2)" "unprognostic (1.40e-1)" "unprognostic (1.77e-1)" 26.1 19.1 4.7 17.9 5.2 5.7 9.8 5.1 5.8 10.4 33.1 12.2 7.9 13.7 9.0 12.7 9.5 12.5 19.2 5.3 9.2 15.6 13.1 16.2 14.7 6.0 7.6 7.5 5.8 15.3 8.3 14.1 7.9 13.8 11.1 17.6 8.9 16.7 11.8 9.8 9.0 23.3 5.3 18.3 8.5 10.1 7.4 13.7 10.7 11.5 13.5 16.9 7.0 8.3 6.0 17.2 20.1 29.4 59.0 19.0 28.6 42.8 42.7 30.7 50.4 10.0 9.8 13.7 34.4 30.0 82.5 11.1 20.2 14.6 47.0 31.6 15.7 28.9 10.9 12.8 45.6 32.1 64.6 28.1 35.7 37.7 30.0 28.2 15.8 15.2 23.3 48.7 50.3 8.4 7.1 7.3 8.0 7.1 13.0 11.4 29.1 7.5 22.0 15.7 2.2 11.8 34.7 8.7 79.9 26.6 10.0 45.8 19.3 26.7 9.8 59.7 61.4 18.6 34.4 11.9 78.9 21.3 60.3 31.4 20.2 22.8 20.3 29.4 21.5 14.7 16.9 22.3 17.8 8.6 15.6 19.8 29.8 22.0 43.5 12.9 22.6 27.0 4.7 5.2 5.1 5.8 5.3 9.2 6.0 7.6 7.9 5.3 7.4 8.3 28.5 9.6 19.0 26.4 26.0 46.7 19.8 11.7 21.6 28.3 10.0 7.0 24.8 12.8 9.4 12.9 10.4 21.7 32.3 21.9 1.9 12.4 12.0 7.5 15.7 20.7 4.2 4.6 36.6 22.9 33.9 24.4 15.8 9.6 24.1 6.9 26.7 13.2 52.8 28.6 40.1 5.8 6.1 46.5 29.5 5.4 14.3 43.1 151.2 20.6 25.6 23.7 40.2 21.1 36.6 16.8 17.0 28.6 25.0 17.9 7.6 25.5 9.8 17.5 26.3 18.5 29.6 28.0 18.7 12.4 31.1 61.2 29.5 23.7 3.3 16.0 OTX2 ENSG00000165588 "Orthodenticle homeobox 2" P32243 14 56799905-56816693 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "choroid plexus: 108.8;retina: 279.9" "Group enriched" "Detected in some" 11 "Bipolar cells: 170.6;Cone photoreceptor cells: 168.9;Rod photoreceptor cells: 202.5" "Cancer enriched" "Detected in single" 27 "testis cancer: 11.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 249.6;hTERT-RPE1: 57.0;NTERA-2: 199.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA000633, HPA001123" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Vesicles "HPA000633: AB_1079538, HPA001123: " "unprognostic (3.82e-1)" "unprognostic (2.56e-2)" "unprognostic (9.28e-2)" 0.0 0.0 4.1 0.0 1.3 0.0 0.0 8.5 0.5 0.0 108.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.9 2.6 0.0 0.0 0.0 0.0 0.2 8.7 0.0 0.0 0.0 2.5 0.0 2.0 0.0 0.0 279.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 12.8 0.0 0.0 0.8 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 249.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 57.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 199.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 1.3 8.5 0.5 5.9 2.6 0.2 8.7 2.0 0.1 12.8 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 170.6 0.0 0.0 0.3 0.0 0.0 0.0 168.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 202.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OXR1 TLDC3 ENSG00000164830 "Oxidation resistance 1" Q8N573 8 106270144-106752694 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 1458.0;Inhibitory neurons: 1366.9;Late spermatids: 405.5;Microglial cells: 496.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027375, HPA027380, HPA027395" Enhanced Approved Vesicles NA NA 12000 "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA027375: AB_10600087, HPA027380: AB_10601569, HPA027395: AB_10601554" "unprognostic (8.16e-3)" "unprognostic (1.39e-1)" "unprognostic (5.52e-2)" "unprognostic (3.12e-1)" "unprognostic (4.84e-2)" "unprognostic (2.84e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-1)" "unprognostic (2.82e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (6.59e-2)" "prognostic favorable (5.82e-5)" "unprognostic (1.89e-1)" "unprognostic (1.32e-1)" "unprognostic (2.58e-1)" "unprognostic (2.86e-1)" 28.7 57.7 19.2 11.1 27.8 18.6 29.0 14.0 50.3 30.6 0.0 20.1 14.2 27.7 54.5 28.7 22.4 22.1 30.5 25.7 4.3 29.7 38.3 20.0 14.4 19.2 6.4 27.0 17.1 23.9 12.2 17.0 21.3 21.1 21.7 79.5 48.6 47.6 52.1 27.4 12.2 21.7 1.8 19.5 27.3 56.1 10.7 22.2 21.3 59.6 16.4 23.7 17.9 22.2 29.5 11.0 32.3 6.5 41.2 51.4 15.0 23.7 28.3 21.6 27.5 9.7 35.6 29.6 26.8 25.6 13.2 20.4 18.5 21.2 37.3 24.9 20.0 39.8 15.3 18.0 25.5 12.8 22.8 30.3 32.1 23.7 34.9 30.0 24.7 24.2 20.3 106.5 24.6 26.2 38.3 17.3 4.2 43.5 19.4 9.9 25.7 55.7 24.0 36.8 19.4 6.0 10.5 7.3 25.8 14.1 34.1 21.2 18.4 24.6 17.1 22.6 15.6 19.7 13.3 12.1 29.2 3.7 30.9 38.1 9.3 17.8 3.9 17.6 6.5 11.4 6.7 6.2 11.2 7.9 16.0 7.1 4.7 11.0 19.4 7.9 5.2 7.8 19.2 27.8 14.0 50.3 25.7 4.3 19.2 6.4 21.3 1.8 10.7 22.2 54.9 67.3 25.5 125.0 47.1 67.6 57.2 42.6 60.9 89.8 36.7 33.5 58.2 15.7 37.3 35.0 58.4 32.6 44.1 44.3 33.2 16.6 231.2 75.3 32.1 41.8 27.5 19.5 1458.0 17.0 20.0 41.3 39.8 65.3 30.4 29.1 44.6 34.5 19.5 26.9 1366.9 28.2 34.6 33.0 41.4 405.5 34.2 36.3 24.9 496.5 41.1 55.6 22.6 294.0 142.6 23.6 24.9 48.9 73.7 60.4 16.5 16.4 53.5 125.8 19.7 46.4 41.6 140.4 51.6 56.7 75.6 71.1 26.5 33.5 26.4 86.1 P3H1 "GROS1, LEPRE1, LEPRECAN, MGC117314" ENSG00000117385 "Prolyl 3-hydroxylase 1" Q32P28 1 42746335-42767084 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Extravillous trophoblasts: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 193.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012113, HPA016980" Approved Approved Nucleoli,Vesicles "Intracellular and membrane" NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles Nucleoli "HPA012113: AB_2668626, HPA016980: AB_2669498" "unprognostic (3.24e-1)" "unprognostic (1.04e-1)" "unprognostic (9.37e-2)" "unprognostic (4.57e-1)" "unprognostic (2.03e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.95e-7)" "unprognostic (5.41e-2)" "unprognostic (2.70e-3)" "unprognostic (9.16e-2)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" "unprognostic (2.67e-2)" "unprognostic (1.60e-3)" 12.4 11.1 3.6 8.7 3.5 6.1 10.2 3.6 4.4 13.4 7.3 8.3 2.4 13.8 6.1 4.4 9.8 12.0 9.1 3.8 3.8 7.2 13.3 11.6 5.1 5.2 3.5 12.8 6.8 5.9 15.5 37.4 3.8 7.5 5.4 1.3 6.7 5.9 3.0 7.6 7.4 20.3 3.4 11.5 6.7 15.2 3.8 7.6 7.6 3.9 5.1 12.3 8.5 3.6 8.7 22.3 48.7 115.0 112.8 85.4 20.1 101.8 131.9 71.9 121.7 11.3 18.8 13.0 79.7 193.0 29.2 7.8 20.9 25.9 49.2 19.5 26.3 30.5 32.2 32.6 65.2 30.9 34.0 73.8 17.4 72.6 30.9 102.4 102.9 18.3 17.5 16.1 49.0 4.7 20.6 17.8 53.1 4.7 16.0 19.9 71.9 17.7 38.2 4.9 10.2 17.3 62.5 1.7 45.8 85.2 3.7 127.0 85.1 53.8 47.2 43.4 41.2 14.5 17.5 11.9 61.5 41.5 77.0 5.0 18.9 16.8 8.3 20.4 8.8 4.1 6.3 7.0 23.6 3.3 5.1 5.3 1.8 17.8 26.3 10.9 12.4 9.3 3.6 3.5 3.6 4.4 3.8 3.8 5.2 3.5 3.8 3.4 3.8 3.6 13.7 3.2 2.3 5.9 10.5 0.0 6.4 0.0 6.2 10.2 4.5 6.5 5.0 7.2 0.6 11.0 25.0 47.9 11.1 0.4 0.0 11.5 17.1 3.2 30.1 16.4 6.1 11.3 12.9 7.6 56.6 34.4 3.6 4.4 1.3 28.8 16.8 11.3 17.6 15.2 10.8 2.5 0.0 8.7 0.0 10.8 19.3 11.7 0.0 9.4 10.5 3.5 6.2 9.5 6.9 7.4 2.0 16.1 11.2 3.4 1.7 1.9 0.7 22.1 0.0 17.2 22.3 30.6 18.8 3.5 0.0 17.5 9.6 27.0 1.9 4.5 P4HB "DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB" ENSG00000185624 "Prolyl 4-hydroxylase subunit beta" P07237 17 81843159-81860856 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chaperone, Isomerase" "Craniosynostosis, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1856.8;pancreas: 2446.9" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 1077.9;Extravillous trophoblasts: 1349.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012463, HPA018884" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No No 110000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB012463: , HPA018884: AB_1854896" "unprognostic (9.47e-3)" "unprognostic (1.09e-2)" "unprognostic (2.99e-2)" "unprognostic (7.14e-3)" "unprognostic (7.75e-3)" "unprognostic (1.05e-2)" "unprognostic (1.30e-1)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (4.73e-3)" "unprognostic (1.43e-1)" "unprognostic (3.93e-2)" "prognostic unfavorable (2.30e-11)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (4.99e-3)" "unprognostic (3.19e-3)" 266.5 507.8 34.6 209.8 35.7 517.1 225.5 39.1 35.7 272.0 59.6 258.4 640.2 206.5 133.0 618.7 183.4 202.0 318.4 31.7 50.2 270.7 1856.8 301.3 104.0 48.9 37.1 187.8 2446.9 144.3 330.0 334.3 40.8 335.8 173.6 23.3 948.1 184.2 328.5 370.4 554.7 179.8 39.8 428.6 539.2 68.8 58.7 89.3 244.8 150.8 137.9 233.7 322.9 43.7 690.3 580.7 236.8 687.5 813.4 726.7 593.6 1038.5 1081.1 741.9 934.5 550.4 576.9 264.4 501.8 1120.2 407.5 464.1 248.8 647.4 254.1 145.8 320.5 355.2 362.9 953.6 1010.8 1146.4 613.4 618.8 494.8 478.2 596.7 843.0 1250.1 182.1 273.6 978.2 559.5 566.4 260.5 723.2 157.7 791.0 463.8 261.8 342.5 614.0 453.2 492.8 248.7 301.1 586.1 1693.1 808.1 289.6 855.3 1601.2 644.1 980.5 503.1 574.3 586.6 743.5 407.9 204.8 1372.0 591.3 825.4 198.3 268.1 163.0 202.6 154.4 209.8 83.9 138.9 165.7 174.7 68.1 74.9 114.6 72.9 157.0 115.3 311.5 105.6 372.4 34.6 35.7 39.1 35.7 31.7 50.2 48.9 37.1 40.8 39.8 58.7 43.7 122.3 102.5 162.1 23.2 151.4 120.1 163.6 371.0 140.6 59.2 283.0 170.8 24.1 247.4 211.7 112.2 33.3 790.2 208.9 420.7 41.1 671.9 43.5 78.4 196.8 153.9 199.9 140.9 15.3 1077.9 1349.1 272.5 388.9 209.1 99.1 210.4 190.2 840.7 435.9 62.2 16.2 610.9 189.2 186.9 125.5 64.9 141.4 180.3 136.9 20.6 263.3 122.7 230.7 13.6 19.6 575.2 465.6 112.1 664.3 310.6 914.2 105.0 91.3 54.3 157.8 103.4 226.7 83.4 94.1 302.3 144.6 1001.2 138.8 378.4 475.4 220.8 PAFAH1B1 "LIS1, MDCR, MDS, NudF, PAFAH" ENSG00000007168 "Platelet activating factor acetylhydrolase 1b regulatory subunit 1" P43034 17 2593210-2685615 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Lipid degradation, Lipid metabolism, Mitosis, Neurogenesis, Transport" "Developmental protein" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 640.0;Late spermatids: 1864.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004489, HPA020036" Approved Supported Centrosome NA NA 860000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Centrosome "CAB004489: AB_627889, HPA020036: AB_1854925" "unprognostic (1.54e-3)" "unprognostic (6.84e-2)" "unprognostic (2.10e-1)" "unprognostic (2.51e-1)" "unprognostic (2.13e-1)" "unprognostic (3.19e-3)" "unprognostic (3.17e-2)" "unprognostic (6.36e-2)" "unprognostic (2.27e-1)" "unprognostic (6.62e-2)" "unprognostic (3.89e-3)" "unprognostic (5.80e-2)" "prognostic favorable (3.16e-4)" "unprognostic (3.31e-1)" "unprognostic (3.51e-1)" "unprognostic (7.45e-2)" "unprognostic (5.58e-2)" 34.8 32.2 35.5 27.2 43.1 4.0 32.6 31.5 46.5 38.3 6.7 46.4 30.5 43.9 26.9 38.0 36.7 31.8 51.1 46.2 47.4 41.4 30.0 37.3 30.9 41.3 38.4 35.4 26.3 56.4 38.4 32.4 48.1 32.6 32.8 47.2 32.4 38.6 87.7 42.1 36.5 44.4 30.2 31.0 34.6 55.7 36.7 41.5 43.9 73.2 38.8 35.7 37.8 38.0 51.3 53.3 81.8 28.4 66.9 74.1 27.3 76.5 67.1 56.3 53.0 69.7 18.7 64.5 63.5 100.3 27.4 53.5 74.4 59.8 80.6 50.9 48.4 56.4 48.8 27.3 69.3 37.5 66.4 68.8 73.5 58.8 58.1 71.7 58.1 51.8 38.8 32.7 84.8 21.1 58.3 28.6 36.7 30.5 27.0 39.5 67.6 30.0 62.5 30.5 37.4 62.0 63.0 34.5 65.5 51.8 36.5 30.1 84.9 71.5 17.1 57.1 61.0 24.7 32.1 28.8 60.4 33.7 66.2 2.6 1.7 3.4 4.7 2.5 5.2 2.9 4.1 3.3 2.5 2.4 4.9 3.8 2.6 3.6 3.8 1.5 5.1 2.4 35.5 43.1 31.5 46.5 46.2 47.4 41.3 38.4 48.1 30.2 36.7 38.0 73.7 121.8 92.2 90.8 82.7 118.7 114.8 74.3 63.2 102.4 52.1 42.9 136.3 30.0 101.6 35.0 50.1 56.4 117.2 77.4 35.2 77.2 640.0 82.2 95.5 77.2 34.1 45.9 178.1 56.3 76.7 74.7 87.7 100.9 93.7 45.1 43.2 32.3 60.2 102.6 161.8 43.7 57.0 46.3 77.0 1864.4 64.0 77.6 56.9 104.9 90.3 60.7 97.9 115.1 193.5 100.8 61.5 56.8 91.7 91.6 76.9 55.0 80.7 65.8 46.0 84.5 133.0 256.8 78.1 69.7 132.6 129.6 92.7 54.7 39.2 122.4 PAM16 "Magmas, Tim16, TIMM16" ENSG00000217930 "Presequence translocase associated motor 16" Q9Y3D7 16 4331549-4355607 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 109.3" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.2;Gastric mucus-secreting cells: 36.2;Plasma cells: 39.5;Squamous epithelial cells: 81.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 184.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062721 Approved Nucleoplasm,Microtubules,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Mitochondria" Microtubules "HPA062721: AB_2684849" "unprognostic (2.69e-2)" "unprognostic (1.64e-1)" "unprognostic (4.06e-1)" "unprognostic (6.81e-2)" "unprognostic (6.98e-2)" "unprognostic (9.68e-2)" "unprognostic (1.83e-1)" "unprognostic (6.32e-2)" "unprognostic (1.99e-1)" "unprognostic (1.39e-1)" "unprognostic (4.79e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (5.73e-5)" "unprognostic (7.25e-2)" "unprognostic (2.22e-1)" "unprognostic (3.56e-1)" "prognostic favorable (1.33e-4)" 26.2 44.3 16.2 6.4 16.9 14.4 24.5 14.8 29.0 21.8 15.6 23.8 14.9 20.5 7.0 25.9 22.3 3.9 70.7 16.4 16.2 28.7 66.4 22.4 7.6 15.5 15.9 20.0 39.2 7.4 27.7 6.2 15.6 20.6 4.8 4.7 19.1 8.2 109.3 21.5 19.6 5.1 14.9 22.4 26.8 34.5 15.9 5.8 17.9 17.6 6.1 26.2 20.7 16.2 20.7 41.2 13.8 41.1 5.2 15.2 44.1 34.3 9.8 23.3 15.5 39.0 28.5 49.4 43.7 10.6 22.6 28.5 12.0 16.3 5.5 56.1 87.8 44.8 26.0 20.4 23.4 33.0 34.6 17.7 27.6 17.2 13.0 12.5 13.2 44.1 68.9 24.8 13.2 57.1 40.1 92.8 41.6 16.2 71.5 54.5 18.6 61.5 10.0 12.8 61.8 49.6 32.7 31.7 52.4 8.3 25.7 54.0 13.2 26.0 41.9 184.8 49.7 34.0 46.7 71.1 15.3 30.3 34.8 0.3 25.0 3.2 17.9 16.2 17.0 26.0 16.3 16.4 17.5 23.2 20.0 20.7 14.3 18.3 18.1 33.2 21.7 18.9 16.2 16.9 14.8 29.0 16.4 16.2 15.5 15.9 15.6 14.9 15.9 16.2 2.6 3.2 4.8 0.0 12.8 4.0 1.4 6.9 67.2 0.8 9.8 7.7 0.5 10.0 5.0 0.0 0.0 2.3 3.7 1.8 7.9 4.0 3.3 14.3 11.9 4.4 0.0 18.5 0.0 3.1 2.8 7.0 36.2 10.0 1.3 12.0 3.3 14.6 1.6 1.7 0.0 2.6 2.0 4.3 1.5 2.2 5.0 6.9 1.8 0.0 4.5 0.4 0.0 0.0 0.0 4.8 2.5 3.8 39.5 1.2 5.5 7.3 5.1 0.6 6.6 2.0 5.1 9.7 13.7 81.3 5.8 1.2 8.8 1.7 3.5 1.3 PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 240.4;Distal enterocytes: 202.4;Hepatocytes: 111.5;Proximal enterocytes: 181.3;Theca cells: 96.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Cell line enhanced" "Detected in many" "BJ: 189.8;fHDF/TERT166: 473.2;HHSteC: 196.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA071224: AB_2686366, HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favorable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.21e-5)" "unprognostic (3.46e-3)" 33.3 135.2 6.3 26.6 7.0 2.0 20.9 6.2 9.5 17.8 6.2 79.9 29.5 8.5 3.1 10.2 12.4 20.7 11.6 5.8 6.2 23.8 77.0 70.4 11.0 6.9 6.6 27.5 26.1 2.1 3.0 58.5 7.5 6.7 64.3 2.3 16.4 3.4 4.7 3.5 61.8 16.7 6.8 8.5 9.2 11.7 8.0 3.0 21.3 8.7 14.8 16.6 11.5 7.2 19.9 20.0 6.4 0.3 129.4 164.8 0.3 189.8 157.7 110.4 79.9 1.0 4.1 0.1 9.8 473.2 3.5 8.5 13.9 13.3 125.2 0.2 10.0 8.8 13.4 0.1 196.5 0.2 3.8 58.7 0.3 63.7 5.2 135.6 94.2 1.4 0.0 89.4 79.2 74.1 0.1 0.7 7.4 4.8 24.1 0.4 0.1 0.4 117.5 8.7 0.9 1.6 92.5 3.3 1.1 12.6 13.5 5.3 120.0 38.2 22.5 131.5 13.9 0.3 1.0 0.3 18.3 0.2 0.2 0.0 1.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 7.7 0.0 0.0 0.8 6.3 7.0 6.2 9.5 5.8 6.2 6.9 6.6 7.5 6.8 8.0 7.2 49.5 240.4 38.2 3.6 2.6 2.3 0.9 18.0 1.8 0.2 11.5 4.7 4.4 8.6 13.8 9.2 0.0 0.5 0.8 202.4 13.7 6.4 1.2 2.6 18.7 23.2 12.6 5.2 22.2 30.2 0.8 36.1 15.3 11.6 0.0 20.3 36.0 111.5 11.5 0.0 27.6 26.5 4.1 29.8 50.7 0.8 17.4 51.0 1.8 30.0 5.2 1.3 0.0 21.6 1.0 19.4 46.1 5.3 3.1 2.1 181.3 9.8 3.4 0.0 13.1 1.0 20.4 1.2 0.7 1.1 1.3 1.4 1.7 96.4 74.3 1.1 PAX1 ENSG00000125813 "Paired box 1" P15863 20 21705659-21718486 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "parathyroid gland: 162.1" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 7.7" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "SCLC-21H: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (9.74e-2)" "unprognostic (3.45e-2)" "unprognostic (3.01e-1)" "unprognostic (2.64e-2)" "unprognostic (1.04e-2)" "unprognostic (2.33e-2)" "unprognostic (4.04e-2)" "unprognostic (2.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.36e-1)" "unprognostic (8.08e-2)" 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 162.1 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.1 0.9 0.0 19.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.5 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 PAX2 ENSG00000075891 "Paired box 2" Q02962 10 100735396-100829944 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 29.6;kidney: 85.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 145.3;Distal tubular cells: 49.0;Endometrial ciliated cells: 129.5;Glandular and luminal cells: 246.0" "Group enriched" "Detected in some" 19 "endometrial cancer: 6.7;ovarian cancer: 7.0;renal cancer: 14.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "AN3-CA: 14.4;EFO-21: 22.6;RPTEC TERT1: 16.0" "Group enriched" "Detected in some" 9 "cerebellum: 1.3;pons and medulla: 3.4" "Group enriched" "Detected in some" 7 "cerebellum: 3.6;medulla oblongata: 5.6;spinal cord: 4.9" "CAB013024, HPA047704, HPA070751" Enhanced Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB013024: AB_2533990, HPA047704: AB_2636861, HPA070751: AB_2686305" "unprognostic (3.98e-2)" "unprognostic (9.55e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (4.85e-2)" "unprognostic (5.54e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-1)" "unprognostic (1.24e-2)" "unprognostic (6.59e-2)" "unprognostic (9.18e-2)" "unprognostic (3.30e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-1)" "unprognostic (6.34e-2)" "unprognostic (8.26e-2)" 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.2 0.4 5.4 0.2 0.0 0.0 1.8 29.6 0.0 8.4 0.0 0.0 0.5 0.4 85.3 0.1 0.0 0.0 6.8 1.6 0.2 0.4 5.9 0.8 0.0 3.3 0.2 0.0 1.2 0.0 11.5 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 14.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 22.6 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 16.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 2.2 0.4 0.5 0.4 6.8 1.6 3.3 6.3 0.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.4 5.9 0.0 0.0 145.3 0.0 0.0 0.0 0.0 49.0 0.0 9.4 129.5 14.8 0.6 0.0 0.0 0.5 0.2 0.0 0.2 0.0 246.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.5 0.0 1.1 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 27.6 0.0 0.5 0.0 0.0 0.6 1.1 1.2 0.0 0.0 0.0 1.2 0.0 0.1 0.0 PAX3 "HUP2, WS1" ENSG00000135903 "Paired box 3" P23760 2 222199887-222298998 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Myogenesis, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Deafness, Disease variant, Proto-oncogene, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;salivary gland: 4.8;skeletal muscle: 3.6;skin 1: 2.9" "Group enriched" "Detected in some" 4 "Early spermatids: 14.4;Late spermatids: 34.8;Melanocytes: 33.8;Skeletal myocytes: 12.8" "Cancer enriched" "Detected in some" 24 "melanoma: 20.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 9.0;BJ hTERT+ SV40 Large T+ RasG12V: 10.6;HBF TERT88: 8.0;RH-30: 17.5;SK-MEL-30: 29.1" "Group enriched" "Detected in some" 7 "cerebellum: 3.4;midbrain: 1.4;pons and medulla: 1.3" "Region enhanced" "Detected in many" "midbrain: 7.7" "HPA063659, HPA069000" Enhanced Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA063659: AB_2685080, HPA069000: AB_2686067" "unprognostic (2.57e-2)" "unprognostic (1.48e-2)" "unprognostic (1.27e-2)" "unprognostic (1.65e-1)" "unprognostic (2.61e-2)" "unprognostic (3.70e-1)" "unprognostic (6.18e-2)" "unprognostic (1.41e-1)" "unprognostic (2.26e-1)" "unprognostic (9.70e-2)" 0.5 0.0 0.4 0.0 0.1 0.0 1.0 4.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.3 1.9 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 4.8 0.0 3.6 2.9 0.0 0.0 2.0 0.0 0.0 1.1 1.2 0.0 0.0 0.8 0.1 0.0 0.1 5.5 0.0 0.0 4.9 0.0 0.0 0.0 0.0 6.0 6.5 9.0 10.6 0.0 0.7 0.0 0.0 4.4 0.2 0.0 0.0 0.0 8.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 6.9 0.1 0.0 0.0 0.0 17.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0 29.1 7.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 3.5 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 4.6 0.1 0.0 0.1 3.3 1.9 2.8 2.0 1.2 5.5 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.2 0.0 0.0 2.9 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.8 34.8 0.9 0.1 33.8 1.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.4 5.6 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 PAX6 "AN, AN1, AN2, D11S812E, WAGR" ENSG00000007372 "Paired box 6" P26367 11 31784779-31817961 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 61.6;retina: 68.9" "Group enriched" "Detected in some" 4 "Horizontal cells: 264.2;Muller glia cells: 462.6" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.1;AN3-CA: 20.1;HEK 293: 18.0;HeLa: 14.9;hTERT-RPE1: 50.6;U-251 MG: 16.5" "Region enhanced" "Detected in all" "cerebellum: 54.3" "Low region specificity" "Detected in all" "HPA030775, CAB034143" Enhanced Supported Enhanced Nucleoplasm NA NA "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "CAB034143: AB_1127044, HPA030775: AB_10601243" "unprognostic (2.89e-1)" "unprognostic (2.98e-2)" "unprognostic (8.34e-2)" "unprognostic (3.85e-2)" "unprognostic (4.42e-2)" "unprognostic (7.82e-2)" "unprognostic (2.76e-1)" "unprognostic (1.91e-1)" "unprognostic (4.24e-3)" "unprognostic (1.68e-1)" "unprognostic (1.20e-2)" "unprognostic (3.91e-1)" "unprognostic (8.96e-2)" "unprognostic (1.32e-1)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (3.42e-3)" 0.0 0.6 21.7 0.0 22.9 0.2 0.1 61.6 34.1 0.0 16.5 0.2 1.7 0.0 0.6 0.0 0.0 0.0 0.0 23.6 20.7 0.8 0.1 0.0 0.0 22.0 18.1 0.0 9.2 0.0 4.3 0.0 21.7 0.0 0.3 68.9 0.1 0.0 0.8 0.5 0.9 0.0 21.4 0.0 9.4 1.6 19.6 0.4 0.0 0.0 0.1 0.1 0.1 25.8 0.0 0.2 15.1 20.1 4.6 6.6 5.9 0.0 0.0 0.2 0.0 1.3 3.7 0.1 6.3 2.3 9.0 0.4 1.8 0.0 0.3 0.0 18.0 8.9 14.9 8.4 0.0 0.5 0.0 0.1 0.7 0.1 0.5 50.6 0.0 5.2 7.6 0.0 0.2 0.0 3.7 0.6 0.3 0.0 10.1 0.0 7.3 0.1 0.8 0.6 0.7 0.0 0.4 0.1 0.0 0.0 4.7 0.0 0.0 5.3 0.4 0.0 16.5 0.1 0.2 0.1 8.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 21.7 22.9 61.6 34.1 23.6 20.7 22.0 18.1 21.7 21.4 19.6 25.8 0.2 0.0 0.0 76.7 0.1 0.5 0.0 0.0 0.0 78.8 0.5 0.0 3.8 0.0 0.0 0.0 12.5 0.1 0.1 0.2 0.0 0.0 0.7 0.2 0.5 1.0 74.6 0.0 3.6 0.0 0.3 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.1 264.2 1.6 3.1 0.0 0.0 0.4 0.6 0.0 0.2 0.0 3.7 0.6 462.6 0.0 3.5 0.6 2.5 1.3 0.0 0.0 0.0 0.1 0.2 0.0 30.6 0.0 0.9 0.5 21.4 7.5 0.0 0.0 0.0 0.1 0.1 0.2 0.0 PBX1 ENSG00000185630 "PBX homeobox 1" P40424 1 164555584-164899296 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Steroidogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 382.3;Excitatory neurons: 475.9;Inhibitory neurons: 405.0;Oligodendrocyte precursor cells: 327.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 93.0;NTERA-2: 111.5;SK-BR-3: 186.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003505, HPA003881, CAB018768" Supported Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "CAB018768: AB_675783, HPA003505: AB_1855019, HPA003881: AB_1855020" "unprognostic (2.26e-2)" "unprognostic (1.95e-1)" "unprognostic (9.09e-2)" "unprognostic (2.14e-2)" "unprognostic (5.21e-3)" "unprognostic (6.94e-3)" "unprognostic (5.95e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "unprognostic (2.24e-3)" "unprognostic (2.30e-1)" "unprognostic (8.81e-2)" "unprognostic (1.34e-2)" "unprognostic (2.13e-1)" "unprognostic (5.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.25e-1)" 24.3 32.1 16.5 11.8 22.3 3.1 36.1 10.7 18.0 88.3 1.9 52.3 22.4 136.8 21.6 30.1 74.6 37.6 24.0 15.3 14.1 29.4 7.7 20.7 4.5 8.8 32.7 52.1 48.1 29.5 14.3 19.5 6.7 38.0 19.8 17.1 43.8 53.8 36.3 10.2 19.9 125.2 13.7 10.2 21.9 6.8 12.6 10.9 35.1 26.5 8.1 40.2 41.5 12.1 2.9 74.4 82.4 19.1 50.8 23.3 3.4 25.2 20.9 8.4 6.1 14.2 11.8 0.0 5.5 47.8 4.3 22.8 31.7 8.1 3.6 3.1 31.3 93.0 56.5 0.3 34.7 0.0 22.2 24.4 0.0 5.4 2.1 19.2 0.3 0.0 0.2 0.0 2.2 47.1 0.2 0.6 111.5 3.8 4.5 0.0 21.6 27.0 6.3 44.1 2.5 39.6 27.8 186.1 0.1 71.4 73.2 0.0 0.5 3.7 8.6 24.2 8.1 8.5 61.2 0.1 0.4 0.2 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 16.5 22.3 10.7 18.0 15.3 14.1 8.8 32.7 6.7 13.7 12.6 12.1 28.6 22.4 18.6 382.3 2.8 22.8 115.0 39.8 70.6 39.9 129.9 87.8 50.0 98.7 25.3 33.1 110.5 101.3 1.5 29.2 33.2 47.9 91.3 47.7 144.3 47.0 90.9 30.3 475.9 68.7 7.3 126.7 32.1 38.5 71.7 57.6 68.9 18.7 9.7 5.0 405.0 38.2 50.8 1.9 17.5 124.4 63.6 12.1 16.0 125.5 1.6 33.5 1.0 327.2 227.4 31.7 72.5 103.8 2.8 41.5 40.4 57.9 37.3 30.6 39.5 142.0 70.9 2.3 17.5 83.6 28.1 104.7 7.6 168.0 43.7 75.9 PCDH12 VE-cadherin-2 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.2" "Group enriched" "Detected in some" 4 "Adipocytes: 38.5;Endothelial cells: 40.0;Hepatic stellate cells: 41.0;Hofbauer cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.6" "Lineage enriched" "Detected in single" 41 "monocytes: 4.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 25.9;Karpas-707: 66.5;U-937: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" NA NA 14000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" 13.4 5.0 0.8 2.5 0.9 0.5 4.9 2.5 1.7 2.7 1.2 2.0 2.0 2.8 0.4 2.1 2.1 4.0 10.8 0.6 0.8 6.0 4.0 15.5 2.6 0.5 0.3 1.7 1.4 2.9 3.6 30.2 0.6 1.9 1.3 1.6 1.4 2.3 4.0 1.7 2.1 5.2 0.3 18.6 2.0 1.1 1.4 0.8 6.5 5.1 1.0 3.2 1.9 0.3 0.1 0.1 1.9 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 5.0 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.6 1.4 0.2 0.1 0.2 0.5 0.2 0.0 0.0 0.4 0.0 0.4 25.9 0.3 0.0 66.5 0.0 0.4 0.1 0.3 0.5 0.0 0.3 0.5 0.2 3.0 0.0 0.1 0.3 0.7 0.1 0.1 0.3 0.2 0.0 1.8 1.8 0.6 0.1 0.9 0.1 0.4 0.4 0.1 0.4 11.7 2.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.8 0.9 2.5 1.7 0.6 0.8 0.5 0.3 0.6 0.3 1.4 0.3 38.5 0.0 1.1 0.0 0.5 0.6 0.0 0.0 1.2 1.3 0.1 0.1 4.0 0.0 0.0 0.0 2.1 0.3 0.3 0.0 3.9 0.1 1.7 0.1 0.1 40.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.1 1.3 0.0 41.0 0.5 34.6 0.0 0.2 0.0 0.0 8.5 0.3 2.5 0.0 1.5 1.8 6.5 0.3 0.5 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.4 0.0 0.4 0.0 0.7 1.0 0.0 0.2 0.2 0.3 0.5 0.2 1.4 0.0 0.2 PCLO "ACZ, DKFZp779G1236, KIAA0559" ENSG00000186472 "Piccolo presynaptic cytomatrix protein" Q9Y6V0 7 82754012-83162930 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 25.6;pituitary gland: 11.1;retina: 21.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 655.4;Inhibitory neurons: 746.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 25.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 28 "REH: 263.3;U-2 OS: 284.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015858, HPA029579, CAB079012" Approved Supported Approved "Nuclear speckles,Plasma membrane" NA NA 6000000 "Cluster 58: Brain - Synaptic function" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles, Plasma membrane" "CAB079012: , HPA015858: AB_1855071, HPA029579: AB_10602044" "unprognostic (1.32e-2)" "unprognostic (1.99e-1)" "unprognostic (9.33e-2)" "unprognostic (1.31e-1)" "unprognostic (2.08e-2)" "unprognostic (1.52e-1)" "unprognostic (4.49e-3)" "unprognostic (6.14e-2)" "unprognostic (4.61e-2)" "unprognostic (1.82e-1)" "unprognostic (3.00e-1)" "unprognostic (1.56e-1)" "unprognostic (4.79e-6)" "unprognostic (5.15e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-5)" "unprognostic (6.62e-5)" 1.8 4.2 4.0 0.2 5.5 0.0 2.4 25.6 22.4 1.5 0.0 2.1 1.5 0.3 3.8 2.3 1.0 0.9 1.4 7.8 1.7 4.4 0.1 0.8 0.1 0.0 0.0 0.8 3.9 4.4 11.1 0.3 0.0 2.5 1.7 21.7 2.5 2.5 0.1 2.0 1.7 0.1 0.0 0.5 1.5 3.7 1.3 1.2 4.6 0.1 0.2 0.6 2.6 4.2 1.2 1.6 1.9 0.0 0.8 0.1 0.0 0.7 0.7 0.5 1.0 0.3 0.7 0.0 0.0 0.8 7.7 0.6 5.7 2.4 2.4 0.3 0.8 0.0 1.2 0.1 0.0 0.8 0.2 0.4 1.8 0.0 9.6 0.5 0.0 0.1 0.0 0.0 0.8 0.8 0.2 0.0 2.0 1.0 4.7 263.3 4.2 0.0 1.9 0.9 4.9 3.4 0.2 2.7 0.6 1.2 3.4 0.6 0.0 0.0 284.5 1.2 0.6 0.2 0.0 0.5 1.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.5 25.6 22.4 7.8 1.7 0.0 0.0 0.0 0.0 1.3 4.2 0.6 9.6 17.9 40.5 0.0 2.5 9.0 3.2 13.6 121.9 11.0 9.7 31.2 22.8 12.6 1.8 131.3 1.9 0.0 22.9 7.9 6.4 13.0 7.4 6.7 2.5 60.1 0.0 655.4 4.9 0.4 2.4 20.4 13.5 0.0 24.2 0.0 0.2 1.7 85.8 746.4 15.0 2.0 0.0 0.0 7.9 2.8 0.4 0.0 50.6 0.0 16.2 0.0 73.9 73.7 2.5 21.9 6.4 0.0 3.9 13.5 23.0 7.7 86.9 0.0 0.3 3.2 5.0 19.5 19.3 3.4 0.7 0.3 37.5 9.3 6.0 PCNT "KEN, KIAA0402, PCN, PCNT2, PCNTB, SCKL4" ENSG00000160299 Pericentrin O95613 21 46324141-46445769 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 239.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "dendritic cells: 4.6;granulocytes: 6.0;T-cells: 8.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016820, HPA019887, HPA032101" Uncertain Supported "Centriolar satellite,Centrosome,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 37: Myocytes - Muscle contraction" Centrosome "Centriolar satellite, Cytosol" "HPA016820: AB_1855079, HPA019887: AB_1855080, HPA032101: AB_2674151" "unprognostic (9.07e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-2)" "unprognostic (1.30e-2)" "unprognostic (5.35e-2)" "unprognostic (3.40e-3)" "unprognostic (1.27e-2)" "unprognostic (2.59e-1)" "unprognostic (9.29e-2)" "unprognostic (1.35e-2)" "unprognostic (1.59e-3)" "unprognostic (3.86e-2)" "unprognostic (1.95e-2)" "unprognostic (5.83e-2)" "unprognostic (2.90e-1)" "unprognostic (3.36e-1)" "unprognostic (5.86e-2)" 9.7 11.1 7.6 5.9 10.5 17.7 8.9 4.2 11.9 8.6 5.3 10.7 4.1 8.2 4.3 11.7 8.5 3.6 28.3 6.0 5.4 7.7 10.9 8.2 8.2 9.0 3.9 9.6 7.8 4.3 20.3 3.5 9.5 8.2 4.3 4.6 9.7 4.2 239.2 12.3 10.1 4.4 2.6 11.5 9.5 25.6 4.7 12.5 8.4 52.0 5.5 9.6 9.2 7.4 15.4 11.6 18.0 11.1 8.9 8.8 11.3 11.6 8.0 11.3 10.0 14.2 9.7 15.2 7.3 13.4 15.3 10.8 14.6 9.9 7.8 44.9 20.4 40.2 24.1 11.3 3.1 20.6 16.1 4.8 7.5 15.2 7.6 5.5 8.8 15.8 20.9 22.4 15.8 25.4 20.6 21.3 18.0 13.9 8.0 25.3 7.2 13.5 8.7 16.3 22.1 9.8 25.4 15.7 8.0 4.4 14.8 16.0 12.1 20.4 10.2 11.7 18.9 19.3 17.2 16.4 12.6 19.9 11.1 6.0 0.6 1.2 1.5 0.5 4.6 0.3 0.7 4.8 2.0 0.1 0.5 8.8 0.4 0.4 1.0 4.6 0.8 2.0 7.6 10.5 4.2 11.9 6.0 5.4 9.0 3.9 9.5 2.6 4.7 7.4 10.5 28.9 32.0 19.9 8.6 8.3 5.7 7.0 13.6 15.0 8.9 8.6 35.7 10.0 15.3 0.0 6.2 6.4 36.7 14.0 0.0 7.1 20.4 17.0 19.9 10.1 15.6 36.2 38.1 7.6 7.4 13.1 25.0 17.8 16.4 25.4 7.1 9.0 23.3 23.5 39.0 11.2 4.1 6.9 5.5 25.6 12.8 12.7 0.0 17.8 14.7 6.8 25.7 10.6 21.9 5.7 5.7 12.0 31.4 4.2 5.7 4.1 13.0 11.1 26.3 61.3 14.2 40.5 39.8 25.0 7.1 6.4 18.8 15.1 10.4 5.1 PCYT1A "CT, CTPCT, PCYT1" ENSG00000161217 "Phosphate cytidylyltransferase 1, choline, alpha" P49585 3 196214222-196287957 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Cone-rod dystrophy, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035428 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA035428: AB_10602045" "unprognostic (8.58e-3)" "unprognostic (2.63e-1)" "unprognostic (8.45e-2)" "unprognostic (8.61e-3)" "unprognostic (2.87e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.65e-5)" "unprognostic (8.52e-2)" "unprognostic (5.99e-2)" "unprognostic (1.65e-2)" "unprognostic (6.72e-3)" "unprognostic (1.74e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.47e-2)" "unprognostic (7.16e-3)" "unprognostic (2.41e-2)" 31.4 24.4 15.2 30.0 16.0 45.3 21.0 16.6 15.8 16.7 17.8 25.7 60.3 19.1 13.9 31.0 15.6 20.7 46.4 15.5 21.1 18.3 20.7 22.5 22.9 18.8 18.0 15.8 16.8 22.7 12.9 20.1 18.5 16.6 22.9 14.4 19.3 18.6 73.8 43.0 49.1 23.0 17.5 25.9 24.2 22.4 18.1 18.1 17.2 42.1 26.8 21.0 19.8 17.1 92.6 36.6 25.8 37.2 52.2 53.9 37.0 68.2 47.1 59.2 51.8 92.3 32.8 23.9 215.2 78.1 60.2 71.4 40.5 52.1 50.4 42.1 28.6 68.6 40.6 39.5 45.2 34.3 56.7 47.4 40.0 55.9 39.6 35.4 63.0 21.0 38.3 53.3 58.1 79.6 19.9 17.3 21.4 55.7 53.0 34.5 31.0 37.5 35.7 53.6 25.4 18.3 44.5 79.5 44.2 32.8 114.1 37.2 88.5 45.5 25.2 61.8 92.7 45.8 101.1 44.1 69.6 43.8 56.9 9.6 9.2 10.4 8.8 9.3 7.5 7.2 6.5 9.7 9.1 6.3 4.2 6.3 21.0 9.4 11.0 5.9 14.9 5.2 15.2 16.0 16.6 15.8 15.5 21.1 18.8 18.0 18.5 17.5 18.1 17.1 24.7 16.0 25.7 15.3 19.9 14.5 9.4 19.7 14.2 15.9 14.1 9.4 70.1 20.0 17.5 14.7 25.0 11.9 27.3 36.4 13.7 24.8 76.3 17.8 22.9 23.2 22.1 12.2 20.4 22.9 17.7 17.0 23.4 15.6 20.8 16.1 26.7 35.6 37.4 8.4 22.7 24.2 6.1 34.6 27.1 67.6 19.9 33.9 19.6 20.6 39.4 13.1 39.1 16.1 17.6 24.6 21.1 28.2 27.2 12.0 67.2 23.2 33.9 12.8 26.3 15.0 19.0 46.0 13.2 30.0 21.5 18.6 25.6 25.5 23.8 12.2 PDCD10 "CCM3, TFAR15" ENSG00000114209 "Programmed cell death 10" Q9BUL8 3 167683298-167734939 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Angiogenesis, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027095 Approved NA NA 190000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA027095: AB_1855101" "unprognostic (3.39e-2)" "unprognostic (2.75e-1)" "unprognostic (4.98e-2)" "prognostic unfavorable (9.34e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.89e-4)" "prognostic unfavorable (2.30e-4)" "unprognostic (4.98e-3)" "unprognostic (2.41e-2)" "unprognostic (9.95e-3)" "prognostic unfavorable (5.22e-5)" "unprognostic (3.08e-2)" "prognostic favorable (5.88e-4)" "unprognostic (1.98e-1)" "unprognostic (2.45e-1)" "unprognostic (3.14e-1)" "unprognostic (5.58e-2)" 34.4 30.4 24.0 39.2 27.1 61.7 41.3 28.4 34.3 24.9 22.6 50.9 48.7 27.3 29.1 50.4 24.4 29.5 35.9 25.6 28.0 43.5 36.4 31.4 53.0 26.9 25.6 25.6 25.7 41.5 21.9 44.4 27.3 31.0 48.7 20.3 31.4 24.7 21.8 27.6 43.4 30.3 27.9 33.1 41.3 44.1 25.9 50.9 37.9 29.6 52.6 50.2 32.3 32.2 133.1 49.3 61.6 39.6 56.7 62.1 67.7 78.5 82.7 89.8 89.9 92.3 153.3 107.5 150.0 73.2 156.5 86.0 73.1 91.1 108.0 172.2 52.9 164.8 59.3 61.1 80.3 109.8 93.0 47.9 92.7 56.9 92.6 64.3 73.3 89.1 129.6 105.2 82.1 117.2 88.4 67.7 79.3 119.3 67.9 51.3 46.9 157.9 112.7 53.5 58.9 52.1 75.2 80.8 148.5 76.8 149.0 92.4 70.5 63.5 41.2 68.9 113.5 113.4 170.9 187.6 75.3 114.6 53.2 224.8 81.7 196.5 82.4 107.0 100.1 136.2 111.2 100.2 79.4 136.4 92.0 95.3 175.0 107.1 138.9 73.2 181.9 133.8 24.0 27.1 28.4 34.3 25.6 28.0 26.9 25.6 27.3 27.9 25.9 32.2 103.3 44.8 42.6 18.6 74.8 108.1 91.0 227.1 69.4 20.2 49.1 57.4 71.1 32.9 120.9 33.1 6.2 106.2 76.9 100.1 105.7 101.4 76.0 58.8 48.3 69.8 34.6 123.3 48.0 122.0 112.3 52.9 62.7 61.4 62.7 34.8 45.3 41.5 91.2 20.2 33.8 75.4 120.1 53.8 73.6 33.5 49.7 89.0 49.8 27.2 100.5 52.9 88.6 19.1 49.7 121.7 103.0 39.5 51.2 97.2 72.0 123.5 92.8 24.1 32.9 37.9 128.4 119.5 103.7 66.6 129.0 103.0 77.9 38.9 55.9 122.7 PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 43.4" "Cell type enhanced" "Detected in many" "Astrocytes: 98.2;Bipolar cells: 38.4;Cardiomyocytes: 131.3;Horizontal cells: 52.2;Inhibitory neurons: 78.8;Smooth muscle cells: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.6;HEL: 15.3;HeLa: 42.5;HUVEC TERT2: 7.4;SH-SY5Y: 17.9;U-138 MG: 11.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.8" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 37000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" 6.5 1.0 1.6 3.1 1.3 0.2 3.8 3.1 1.3 6.7 1.8 15.0 1.9 4.2 1.4 2.2 4.1 4.7 43.4 1.3 1.5 3.3 1.3 3.9 1.0 1.9 2.3 3.4 6.2 0.6 2.1 11.3 1.2 5.4 7.6 5.7 2.7 3.5 2.2 1.3 9.6 5.2 1.6 2.2 5.1 0.4 2.5 0.6 2.8 1.8 0.5 2.5 3.1 1.4 0.0 0.2 8.6 0.0 1.9 1.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.3 42.5 0.2 0.6 0.0 0.0 1.8 0.0 0.4 0.1 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 1.1 0.0 0.0 0.0 2.7 0.0 0.1 17.9 0.0 0.0 0.1 3.3 0.0 0.0 0.3 11.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 3.1 1.3 1.3 1.5 1.9 2.3 1.2 1.6 2.5 1.4 2.7 0.0 0.0 98.2 0.0 0.3 0.2 0.0 0.6 38.4 0.2 0.3 131.3 4.3 0.6 0.0 0.0 0.0 0.0 28.4 0.0 5.8 0.7 0.5 1.6 3.9 4.2 0.0 4.1 0.5 0.0 11.3 0.0 1.4 17.1 0.0 2.2 0.0 0.7 52.2 78.8 7.0 0.0 0.0 0.7 0.6 1.5 3.1 1.8 27.2 0.5 4.4 0.0 27.6 3.9 0.4 26.9 0.7 0.0 0.5 33.4 3.1 0.0 2.8 6.6 3.6 49.9 0.3 0.9 0.9 0.3 0.0 0.6 0.5 16.4 0.2 PDE4D DPDE3 ENSG00000113448 "Phosphodiesterase 4D" Q08499 5 58969038-60522120 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 74.9;skeletal muscle: 70.4" "Cell type enhanced" "Detected in many" "Astrocytes: 619.3;Excitatory neurons: 2969.7;Inhibitory neurons: 1116.9;Oligodendrocyte precursor cells: 848.0;Oligodendrocytes: 443.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "eosinophil: 57.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 57.9" "Cell line enhanced" "Detected in many" "A549: 62.2;AN3-CA: 70.4;HeLa: 104.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045895 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Cytosol "HPA045895: AB_10960275" "unprognostic (1.14e-1)" "unprognostic (8.73e-3)" "unprognostic (4.35e-2)" "unprognostic (7.87e-2)" "unprognostic (5.97e-2)" "unprognostic (2.03e-1)" "unprognostic (8.10e-4)" "unprognostic (1.17e-1)" "unprognostic (6.59e-2)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (2.65e-1)" "prognostic favorable (4.00e-5)" "unprognostic (1.51e-1)" "unprognostic (8.20e-2)" "unprognostic (1.77e-2)" "unprognostic (2.56e-2)" 8.9 1.3 3.3 9.8 9.9 74.9 4.6 0.0 11.3 5.3 0.0 21.0 5.5 7.4 18.4 13.7 7.3 9.1 15.7 4.4 4.2 17.2 2.8 13.3 5.3 7.0 2.0 3.0 3.7 5.5 6.7 16.6 1.2 19.9 15.0 21.4 7.4 21.2 70.4 4.5 7.0 15.3 0.8 4.0 10.3 3.4 3.8 8.6 7.4 34.4 5.6 22.0 8.2 5.7 0.1 62.2 12.8 70.4 2.3 4.4 10.1 1.6 1.8 3.4 4.9 24.5 2.0 4.8 0.2 0.5 10.3 10.6 0.0 2.8 5.9 2.9 7.0 9.2 104.6 5.3 9.1 4.4 0.7 9.3 2.3 9.6 1.7 1.1 7.3 0.3 0.0 1.6 5.9 4.5 3.6 10.3 2.4 1.8 3.2 1.2 16.0 10.5 15.9 23.5 2.3 8.0 16.4 27.1 14.2 11.4 1.9 9.3 8.5 0.9 0.2 12.0 3.3 3.5 0.1 0.5 10.3 17.3 2.7 4.2 2.0 57.9 1.5 0.1 1.5 11.0 1.4 0.7 1.4 11.3 0.9 0.7 3.1 0.4 0.2 0.0 0.8 1.1 3.3 9.9 0.0 11.3 4.4 4.2 7.0 2.0 1.2 0.8 3.8 5.7 22.5 32.1 110.0 619.3 32.3 10.6 30.1 6.6 35.3 20.2 5.1 2.7 35.7 8.6 30.2 42.3 73.0 11.3 118.6 28.1 11.7 0.6 21.4 19.0 8.6 16.9 33.4 2.1 2969.7 1.8 25.7 27.5 40.2 21.9 22.2 0.3 17.2 0.8 5.2 1.7 1116.9 18.2 6.1 4.8 11.1 36.6 1.5 29.5 10.6 407.5 6.0 12.0 29.9 848.0 443.3 8.2 11.9 4.9 44.4 43.3 8.9 27.5 19.4 52.8 0.0 64.0 6.3 1.1 7.7 40.6 8.8 3.1 94.3 1.1 11.7 26.5 PDE6D JBTS22 ENSG00000156973 "Phosphodiesterase 6D" O43924 2 231732433-231786272 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 211.9;Late spermatids: 147.9;Spermatocytes: 236.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037433, HPA037434" Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA037433: AB_2675475, HPA037434: AB_10672490" "unprognostic (1.95e-1)" "unprognostic (2.33e-2)" "unprognostic (1.22e-1)" "unprognostic (7.72e-3)" "unprognostic (7.07e-2)" "unprognostic (5.41e-2)" "unprognostic (1.15e-1)" "unprognostic (9.48e-2)" "unprognostic (3.91e-1)" "unprognostic (1.41e-1)" "unprognostic (1.69e-1)" "unprognostic (4.75e-2)" "prognostic unfavorable (4.02e-5)" "unprognostic (1.11e-2)" "unprognostic (1.80e-2)" "unprognostic (1.46e-1)" "prognostic favorable (4.97e-4)" 16.8 28.1 43.4 16.2 47.3 14.6 16.3 47.4 50.7 19.2 38.0 19.6 13.4 17.6 14.9 16.3 15.5 14.2 19.3 44.4 45.7 19.5 15.4 15.2 23.3 45.6 46.0 13.4 13.2 23.5 25.0 23.0 45.7 13.7 17.6 69.6 14.2 17.6 13.7 16.4 15.7 22.0 46.5 18.8 16.2 27.8 45.8 32.4 14.0 16.7 24.0 17.9 16.4 49.6 26.3 20.3 37.0 28.2 43.7 36.1 15.7 27.0 44.6 40.8 56.9 8.1 24.5 21.4 22.7 23.2 74.9 20.4 22.3 30.2 52.6 63.5 26.4 31.2 12.4 13.0 20.2 20.6 17.2 25.5 26.4 39.8 30.4 27.5 44.1 68.3 9.1 23.5 27.5 52.0 67.7 64.4 28.6 39.6 28.1 45.7 17.0 32.9 42.8 19.5 36.4 32.6 23.0 19.4 46.3 36.1 17.5 43.0 19.5 26.5 7.3 57.9 21.4 57.9 26.3 52.6 27.4 38.6 42.5 84.4 48.2 68.4 46.3 48.7 36.3 50.4 46.0 47.3 49.3 55.5 31.7 44.3 42.0 34.4 64.9 55.8 84.4 43.1 43.4 47.3 47.4 50.7 44.4 45.7 45.6 46.0 45.7 46.5 45.8 49.6 20.8 0.0 8.7 18.3 19.5 13.8 12.4 23.6 21.1 14.7 13.3 17.7 13.1 12.8 15.8 12.9 16.7 16.4 18.2 10.2 25.4 23.1 211.9 6.8 9.2 19.6 17.4 15.8 13.4 23.9 21.9 14.7 13.3 6.5 14.5 7.3 19.2 5.0 18.9 11.8 18.1 10.0 14.2 14.4 15.1 147.9 13.1 17.5 23.2 16.9 24.6 22.0 17.5 48.7 34.0 26.0 14.9 12.4 17.0 10.5 11.2 18.4 11.8 29.0 19.7 10.7 24.9 236.8 65.1 20.3 14.2 13.5 18.5 11.5 10.5 11.0 PEX5 "PTS1R, PXR1" ENSG00000139197 "Peroxisomal biogenesis factor 5" P50542 12 7188685-7218574 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Peroxisome biogenesis disorder, Rhizomelic chondrodysplasia punctata, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Early spermatids: 277.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 156.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039259, HPA039260" Enhanced Supported "Golgi apparatus,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Cytosol" "HPA039259: AB_10673419, HPA039260: AB_2676417" "unprognostic (7.44e-2)" "unprognostic (2.54e-2)" "unprognostic (1.41e-1)" "unprognostic (1.86e-1)" "unprognostic (1.27e-1)" "unprognostic (4.46e-1)" "unprognostic (1.48e-1)" "unprognostic (2.20e-2)" "unprognostic (5.14e-2)" "unprognostic (3.72e-2)" "unprognostic (1.63e-2)" "unprognostic (2.92e-1)" "unprognostic (5.70e-2)" "unprognostic (7.31e-3)" "unprognostic (1.96e-1)" "unprognostic (2.13e-2)" "unprognostic (1.13e-1)" 33.1 27.8 43.7 13.2 42.8 8.8 34.2 38.0 43.3 25.0 33.5 25.3 12.1 26.0 10.9 18.8 23.2 13.6 22.0 39.1 38.5 24.5 37.8 22.1 18.6 40.9 41.2 29.2 30.4 18.9 44.1 10.0 41.2 19.7 11.8 13.6 22.2 13.6 74.1 26.2 20.3 15.2 43.1 16.0 22.2 50.9 45.4 39.3 20.0 28.4 20.8 21.7 21.2 40.9 14.7 24.7 13.0 34.2 29.1 19.9 24.3 14.0 16.6 16.2 17.2 36.9 21.8 156.1 8.3 16.2 23.6 18.2 22.1 19.5 16.8 20.8 18.2 13.8 19.0 25.7 15.4 21.3 13.6 22.2 35.2 11.1 34.5 22.0 14.2 75.0 28.2 5.3 14.7 20.0 49.7 18.5 38.6 28.0 13.1 23.7 28.1 21.4 13.0 21.4 10.9 22.6 20.9 45.4 20.1 26.2 10.2 12.5 12.7 18.2 29.9 15.8 17.2 9.5 11.6 53.4 18.0 22.8 12.2 0.0 1.6 2.1 2.9 1.4 3.6 1.9 2.0 2.9 2.6 1.4 2.6 2.6 1.2 2.8 4.1 4.6 0.9 2.2 43.7 42.8 38.0 43.3 39.1 38.5 40.9 41.2 41.2 43.1 45.4 40.9 8.6 12.8 20.1 11.4 5.6 14.5 7.2 5.2 8.0 7.8 9.2 8.5 13.7 14.3 5.6 7.3 8.4 11.3 5.1 9.9 9.8 10.1 277.8 7.0 13.6 10.3 7.2 4.6 31.5 14.9 6.4 7.8 4.1 5.2 3.8 7.2 5.7 17.6 4.7 13.5 22.1 7.2 4.1 5.4 5.0 43.7 14.3 5.2 5.4 1.0 4.6 12.7 5.2 16.1 13.3 10.2 14.2 13.9 2.9 14.1 9.9 19.3 9.8 7.0 19.7 12.0 10.2 32.2 16.6 7.4 15.3 7.7 5.8 9.6 10.4 5.7 PEX6 "PAF-2, PXAAA1" ENSG00000124587 "Peroxisomal biogenesis factor 6" Q13608 6 42963865-42979181 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis" "Amelogenesis imperfecta, Deafness, Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 76.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 78.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025924, HPA074179" Supported Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA025924: AB_1855230, HPA074179: " "unprognostic (7.32e-3)" "unprognostic (2.43e-1)" "unprognostic (1.38e-1)" "unprognostic (9.16e-2)" "unprognostic (9.18e-2)" "unprognostic (3.27e-1)" "unprognostic (8.88e-2)" "unprognostic (5.92e-2)" "unprognostic (3.36e-1)" "unprognostic (7.12e-2)" "unprognostic (7.24e-3)" "unprognostic (5.31e-2)" "unprognostic (3.79e-3)" "unprognostic (1.86e-1)" "unprognostic (1.13e-1)" "unprognostic (1.81e-1)" "unprognostic (1.55e-1)" 11.6 20.5 24.9 9.2 25.2 9.5 12.1 23.9 27.7 19.1 25.5 16.3 9.3 15.5 7.7 16.4 22.7 9.6 18.7 25.1 25.5 16.5 27.7 10.0 14.5 27.2 25.5 26.1 76.2 15.2 24.3 9.6 24.2 21.6 7.8 9.9 14.8 11.4 23.4 14.0 16.3 9.6 23.9 17.5 16.3 16.2 25.1 14.7 19.8 15.0 10.4 17.3 15.7 25.2 35.0 16.4 8.1 30.6 29.6 28.3 8.4 6.0 9.4 4.8 10.0 10.5 10.1 14.1 8.2 14.3 20.5 32.2 28.7 31.1 5.0 27.6 15.2 4.7 24.4 6.2 20.0 4.8 9.4 35.5 35.5 19.9 5.5 39.1 24.7 18.9 25.2 14.1 10.7 3.9 12.7 15.8 10.0 78.8 14.3 26.8 14.3 5.8 12.3 10.0 25.4 11.1 5.6 21.9 32.7 13.1 43.2 21.2 14.0 15.2 2.9 7.5 14.0 21.0 19.8 19.7 5.2 24.6 12.4 1.3 1.3 2.1 1.2 1.1 2.1 1.0 1.8 2.5 1.9 1.9 2.2 2.1 0.8 2.0 0.7 1.0 0.9 1.1 24.9 25.2 23.9 27.7 25.1 25.5 27.2 25.5 24.2 23.9 25.1 25.2 5.6 6.4 2.6 19.9 5.6 5.0 10.2 6.2 10.8 15.2 11.8 12.7 4.1 10.0 5.6 7.3 2.1 11.4 5.4 10.2 13.7 2.8 2.5 17.6 10.6 5.8 5.4 1.7 24.6 1.5 6.7 9.2 11.2 9.1 0.0 19.8 8.6 14.1 5.8 21.9 22.4 8.5 6.1 9.7 3.2 3.6 14.6 5.4 8.8 9.4 4.5 11.8 9.2 13.0 16.6 1.9 10.4 9.4 3.1 6.3 15.1 13.9 14.3 7.0 0.0 13.0 6.6 7.3 2.6 6.3 5.5 7.4 7.8 26.1 10.5 6.6 PEX7 "PTS2R, RD" ENSG00000112357 "Peroxisomal biogenesis factor 7" O00628 6 136822564-136913934 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cataract, Deafness, Disease variant, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049202 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Vesicles" "HPA049202: AB_2680674" "unprognostic (1.36e-2)" "unprognostic (2.07e-2)" "prognostic favorable (1.61e-4)" "unprognostic (4.01e-3)" "unprognostic (2.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.46e-1)" "unprognostic (1.71e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (6.88e-2)" "prognostic favorable (1.85e-10)" "unprognostic (3.57e-1)" "unprognostic (1.44e-1)" "unprognostic (2.52e-2)" "unprognostic (2.65e-1)" 5.2 14.8 4.6 2.0 4.8 3.8 11.9 6.0 5.2 6.8 5.1 7.9 5.3 4.2 17.2 7.3 8.7 4.5 11.7 4.2 4.2 15.6 9.1 4.9 3.2 4.3 4.4 5.0 26.9 17.1 6.0 4.1 4.5 10.4 8.4 6.9 10.6 6.4 10.7 11.2 4.7 3.3 4.4 3.3 15.6 10.0 4.7 3.7 11.0 9.8 3.3 5.4 6.7 5.5 4.4 4.3 4.4 6.2 6.6 9.8 2.4 6.1 8.9 7.5 7.4 4.9 6.0 1.5 11.3 8.3 8.5 5.3 3.3 13.8 9.8 5.7 7.5 6.4 4.3 0.9 13.9 8.1 5.3 9.6 13.1 5.4 7.9 8.7 5.4 12.0 13.0 5.2 10.6 13.4 3.5 7.9 5.0 13.9 8.3 4.8 3.4 5.7 17.4 6.4 8.3 10.6 6.5 9.0 8.4 4.9 5.8 7.7 2.5 4.8 1.7 7.3 5.3 6.9 5.1 0.0 4.2 6.4 4.9 2.9 1.3 2.2 0.7 1.0 0.7 1.5 1.3 1.6 2.3 1.0 2.4 1.5 0.9 1.6 1.9 1.8 2.3 0.9 4.6 4.8 6.0 5.2 4.2 4.2 4.3 4.4 4.5 4.4 4.7 5.5 4.9 3.2 9.4 10.7 6.3 12.1 14.9 16.5 9.1 9.1 19.5 13.8 18.7 11.5 14.7 11.0 8.4 19.6 2.3 11.6 60.7 16.5 12.5 18.7 6.4 5.6 10.3 15.8 12.4 22.7 21.0 6.8 10.2 11.1 14.0 7.9 6.1 7.0 12.4 0.0 14.7 21.8 30.5 5.7 6.2 10.2 9.0 6.4 14.2 5.6 11.9 20.8 4.1 17.6 19.9 16.7 13.2 9.8 3.7 16.0 15.0 38.3 16.1 9.9 6.6 5.7 8.2 30.6 16.7 15.4 18.2 17.1 6.6 24.3 17.2 17.4 PHC1 "EDR1, HPH1, RAE28" ENSG00000111752 "Polyhomeotic homolog 1" P78364 12 8913896-8941467 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, DNA-binding" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3" "Cancer enriched" "Detected in many" 7 "testis cancer: 32.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "BEWO: 141.8;NTERA-2: 492.6;SuSa: 178.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006973 Approved Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA006973: AB_1855278" "unprognostic (4.00e-2)" "unprognostic (1.79e-1)" "unprognostic (2.57e-1)" "unprognostic (1.73e-1)" "unprognostic (4.21e-3)" "unprognostic (7.46e-2)" "unprognostic (1.33e-1)" "unprognostic (1.59e-1)" "unprognostic (2.52e-1)" "unprognostic (1.47e-1)" "unprognostic (4.79e-3)" "unprognostic (1.69e-1)" "unprognostic (1.34e-2)" "unprognostic (7.55e-2)" "unprognostic (2.47e-1)" "unprognostic (9.27e-2)" "unprognostic (3.63e-2)" 20.1 18.1 22.9 17.7 21.1 7.5 23.1 26.1 21.8 46.8 31.3 32.1 6.9 42.0 13.3 20.7 44.6 15.7 20.4 21.7 21.4 24.9 6.9 21.4 16.1 20.5 22.9 47.2 25.5 26.4 75.7 14.1 19.3 31.7 9.4 40.0 23.6 20.2 16.1 10.7 21.0 22.4 19.2 22.2 22.3 43.3 20.8 28.1 44.3 10.3 14.6 28.0 26.9 19.8 6.6 11.1 46.5 43.0 13.8 14.5 141.8 6.6 13.7 11.3 14.7 7.4 10.5 17.4 5.7 11.3 17.4 5.8 12.9 15.4 15.2 60.8 7.5 22.8 14.5 7.5 15.0 12.4 38.5 18.0 8.0 18.1 18.1 36.2 13.7 19.8 4.6 6.4 11.5 8.2 15.8 22.1 492.6 2.5 3.7 25.1 31.3 0.9 12.3 29.0 9.0 32.1 10.4 23.4 17.4 178.3 3.4 12.4 7.8 20.8 34.5 13.2 9.6 12.8 8.9 24.9 9.3 6.7 14.4 0.6 0.2 0.0 0.8 1.1 0.5 1.1 1.2 1.5 0.1 0.9 1.2 0.9 0.0 0.8 2.8 1.2 0.8 0.8 22.9 21.1 26.1 21.8 21.7 21.4 20.5 22.9 19.3 19.2 20.8 19.8 11.9 16.0 19.8 48.3 7.7 2.4 5.5 4.6 9.1 24.2 10.8 11.2 0.5 11.5 13.1 9.2 27.1 5.9 10.1 0.8 1.9 5.4 26.4 20.0 17.4 11.0 11.4 9.5 36.4 5.2 11.5 11.8 5.1 10.6 19.0 15.5 8.6 2.0 4.4 16.8 44.0 2.7 4.1 5.4 3.9 17.6 14.3 6.0 7.2 12.2 3.2 17.7 7.2 23.1 13.0 4.6 1.9 12.0 3.0 4.5 0.7 5.3 19.2 36.8 0.0 15.8 12.2 17.7 25.1 10.2 2.4 5.1 11.2 8.7 2.0 4.9 PHF6 "BFLS, BORJ, CENP-31, KIAA1823, MGC14797" ENSG00000156531 "PHD finger protein 6" Q8IWS0 X 134373312-134428791 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Epilepsy, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 149.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001023 Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA001023: AB_1079606" "unprognostic (2.38e-3)" "unprognostic (8.21e-2)" "unprognostic (1.99e-1)" "unprognostic (3.04e-3)" "unprognostic (6.03e-3)" "unprognostic (5.20e-3)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.81e-1)" "unprognostic (4.85e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (1.09e-1)" "unprognostic (5.96e-2)" "unprognostic (4.84e-2)" "unprognostic (7.45e-2)" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" 6.7 18.0 6.6 14.2 7.9 8.4 10.8 10.3 9.3 8.3 6.2 9.1 8.9 9.7 32.7 8.2 7.9 6.6 6.7 7.1 8.4 10.2 7.7 6.8 25.3 8.3 7.8 33.3 9.5 16.3 6.2 9.3 8.4 9.2 10.3 12.0 13.2 11.0 5.0 8.3 8.8 8.1 8.6 13.3 9.3 9.2 7.7 20.8 13.2 6.8 29.8 8.6 7.1 11.5 28.2 22.9 98.7 40.8 17.9 22.9 18.7 27.6 22.1 29.1 35.6 13.9 28.5 45.1 61.8 16.9 28.3 24.6 69.4 31.3 48.6 37.2 32.1 44.3 37.7 16.1 19.2 44.2 23.3 15.3 23.2 31.7 39.2 29.1 41.1 43.1 32.6 21.8 35.8 18.7 71.3 21.8 30.1 38.3 31.0 69.6 36.0 34.5 30.7 33.8 34.1 39.9 21.2 19.3 29.5 29.0 18.0 24.0 31.5 26.8 19.2 34.0 42.9 11.1 27.3 60.5 17.7 51.4 34.3 5.9 6.3 4.1 8.0 6.6 8.7 18.7 8.2 7.3 9.5 12.4 9.6 8.2 2.6 11.0 8.4 11.7 9.1 5.5 6.6 7.9 10.3 9.3 7.1 8.4 8.3 7.8 8.4 8.6 7.7 11.5 25.5 22.4 18.4 13.1 42.7 13.0 14.3 28.7 22.2 22.4 17.5 20.3 16.3 11.5 17.8 16.5 18.8 11.8 27.1 9.9 23.5 14.2 3.7 13.0 29.1 18.7 11.4 31.3 27.8 13.8 7.6 17.2 14.8 18.7 24.6 149.5 20.0 15.2 15.1 18.5 23.4 12.5 10.2 15.5 10.2 3.1 20.8 20.2 7.2 29.0 25.3 27.9 21.6 33.2 46.7 14.4 18.7 15.4 23.1 12.3 9.5 19.8 16.5 19.7 26.3 21.0 21.9 10.3 22.0 25.7 11.5 4.7 22.6 69.3 17.7 11.5 PI4KA "PI4K-ALPHA, pi4K230, PIK4CA" ENSG00000241973 "Phosphatidylinositol 4-kinase alpha" P42356 22 20707691-20859417 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 209.1;Inhibitory neurons: 127.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009092, HPA075515" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Plasma membrane" "CAB009092: AB_2164033, HPA075515: AB_2686753" "unprognostic (8.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.21e-1)" "unprognostic (5.01e-3)" "unprognostic (3.19e-2)" "prognostic favorable (5.24e-4)" "unprognostic (2.08e-1)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.29e-1)" "prognostic favorable (7.22e-5)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" "unprognostic (2.35e-1)" "unprognostic (1.50e-1)" 18.8 21.6 45.2 19.2 61.0 24.1 16.8 2.1 74.4 20.4 9.6 23.7 15.8 24.2 9.9 14.3 19.5 13.5 21.5 65.3 9.0 21.3 25.2 19.1 20.5 14.6 4.8 21.4 18.7 34.5 25.2 17.9 14.5 19.5 14.9 27.7 16.5 16.9 23.6 15.1 22.9 21.9 0.0 21.0 26.0 25.7 8.6 34.3 18.0 15.9 18.0 22.2 16.9 43.3 24.5 20.2 17.4 26.3 48.7 29.1 24.9 21.6 32.6 31.3 30.4 15.9 10.2 45.6 12.6 43.9 30.7 21.1 33.4 20.9 19.0 38.9 50.9 47.1 27.1 18.3 24.3 47.0 36.1 26.2 12.9 26.7 14.7 20.4 25.8 13.8 130.2 37.6 24.6 33.8 41.6 16.0 13.8 43.4 20.6 41.1 38.1 8.5 17.3 38.3 42.6 31.0 28.4 32.6 22.6 24.3 27.6 21.3 26.2 56.4 29.1 21.1 18.5 28.6 31.3 35.8 37.4 33.2 24.1 2.1 3.7 5.3 3.2 3.8 3.1 3.4 3.6 3.9 2.5 3.4 3.6 5.0 5.1 7.0 3.3 8.5 4.3 2.2 45.2 61.0 2.1 74.4 65.3 9.0 14.6 4.8 14.5 0.0 8.6 43.3 13.0 12.8 30.4 65.6 14.7 10.1 6.5 7.6 9.6 35.8 17.2 14.4 30.2 20.0 10.5 7.3 47.9 17.8 21.5 19.7 1.9 9.7 36.5 10.3 17.9 15.5 19.2 12.4 209.1 6.3 19.6 15.6 38.7 15.8 12.0 13.8 11.4 19.7 20.1 37.0 127.4 16.7 10.2 21.0 12.6 25.3 19.9 20.2 10.6 39.4 10.9 23.1 16.5 50.3 88.4 8.9 9.7 24.0 15.5 10.1 23.8 10.3 9.6 25.4 26.3 14.5 19.3 35.3 29.6 14.1 9.8 20.0 15.3 26.1 14.3 8.9 PIBF1 "C13orf24, CEP90" ENSG00000083535 "Progesterone immunomodulatory binding factor 1" Q8WXW3 13 72782133-73016461 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Immunity "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 334.5;Oligodendrocyte precursor cells: 143.7;Oligodendrocytes: 138.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052269, HPA066120" Approved Supported "Centriolar satellite" "Secreted to blood" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Centriolar satellite" "HPA052269: AB_2681779, HPA066120: AB_2685621" "unprognostic (1.54e-1)" "unprognostic (4.17e-1)" "unprognostic (6.73e-2)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (3.80e-2)" "unprognostic (3.79e-2)" "unprognostic (3.87e-2)" "unprognostic (4.08e-2)" "unprognostic (2.62e-2)" "unprognostic (2.26e-3)" "unprognostic (1.39e-1)" "unprognostic (6.85e-3)" "unprognostic (8.31e-2)" "unprognostic (2.78e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-1)" 7.6 9.1 5.2 6.7 5.5 10.2 12.2 7.4 7.3 11.5 9.8 7.4 7.0 11.5 10.7 7.1 11.0 8.4 7.5 4.6 4.8 8.3 9.8 8.7 9.9 5.1 5.0 12.6 5.5 8.5 7.5 9.7 4.7 9.8 8.8 10.2 7.4 8.2 6.6 8.5 6.9 8.5 4.7 8.4 8.7 14.3 5.0 13.0 15.5 7.4 8.4 10.1 8.0 6.0 13.1 4.2 16.8 9.8 14.4 25.3 6.5 11.9 15.9 11.8 14.4 5.8 22.1 12.0 13.7 13.2 6.2 11.1 9.1 12.0 18.9 12.2 8.7 8.2 10.9 6.7 18.4 31.0 7.5 16.4 9.4 12.7 30.7 15.1 15.5 8.2 11.7 6.1 15.9 3.7 15.2 18.6 8.9 23.3 3.9 12.0 12.4 12.4 24.5 7.0 9.6 15.4 9.2 6.3 16.3 13.5 10.6 21.8 11.8 6.0 6.3 9.5 7.2 9.7 7.5 6.0 18.0 17.3 13.3 8.4 3.4 6.1 6.0 3.7 6.4 5.9 6.4 6.5 3.0 5.6 8.7 7.3 3.3 8.6 3.6 5.1 5.3 2.5 5.2 5.5 7.4 7.3 4.6 4.8 5.1 5.0 4.7 4.7 5.0 6.0 33.8 32.1 30.8 101.2 21.6 10.3 16.3 10.5 16.5 17.1 15.5 17.8 28.1 14.3 27.7 5.5 16.7 9.4 19.3 6.6 13.7 11.6 334.5 41.5 33.6 20.0 7.2 15.2 115.1 11.1 10.2 20.4 21.4 18.5 24.1 21.8 9.7 5.6 7.1 18.5 119.3 9.7 12.2 8.6 3.5 50.4 19.3 10.3 8.8 92.8 9.8 11.9 17.5 143.7 138.6 12.0 8.5 15.4 11.6 11.8 7.1 6.5 46.3 31.3 13.1 28.9 17.9 59.4 39.2 11.8 8.9 6.0 23.1 25.6 10.0 13.7 PIEZO1 "FAM38A, KIAA0233" ENSG00000103335 "Piezo type mechanosensitive ion channel component 1" Q92508 16 88715338-88785220 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Pancreatic endocrine cells: 85.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 270.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA047185 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA047185: AB_2679973" "unprognostic (1.76e-1)" "prognostic unfavorable (2.37e-4)" "unprognostic (1.77e-1)" "unprognostic (1.12e-2)" "unprognostic (4.08e-2)" "unprognostic (2.34e-2)" "unprognostic (2.64e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (4.39e-2)" "prognostic unfavorable (3.78e-4)" "unprognostic (3.51e-2)" "unprognostic (3.05e-2)" "prognostic unfavorable (8.89e-7)" "unprognostic (2.04e-1)" "unprognostic (3.59e-2)" "unprognostic (2.86e-2)" "unprognostic (3.74e-1)" 79.0 26.4 15.2 20.5 16.0 29.8 65.1 16.5 19.0 30.7 10.4 86.7 7.7 40.4 0.5 48.4 38.1 9.0 29.4 12.9 13.8 57.2 48.2 67.2 14.8 25.0 17.6 15.8 21.9 5.2 6.8 18.6 22.5 49.4 4.8 1.7 33.3 11.2 6.8 48.8 41.1 14.3 17.6 55.2 38.0 5.2 17.4 7.2 32.4 4.3 5.9 65.3 40.4 21.2 42.0 42.1 6.5 31.3 27.6 30.0 155.2 99.9 43.9 36.1 14.0 61.3 68.5 34.2 68.2 48.4 18.0 88.4 13.9 36.0 7.3 33.8 56.0 58.3 77.9 49.4 41.6 26.4 9.3 24.6 19.4 28.3 23.3 21.3 43.9 56.1 80.4 42.8 21.2 270.1 32.7 91.2 14.7 19.7 25.7 77.7 9.3 86.9 16.4 61.1 12.8 3.4 130.5 68.0 17.8 6.5 93.0 76.5 120.1 86.0 49.6 58.4 51.6 8.7 21.1 21.2 67.9 46.5 52.2 1.8 5.0 3.3 8.1 9.7 7.8 2.3 6.0 5.5 9.7 3.1 1.0 2.5 0.1 1.0 13.1 1.7 5.0 3.9 15.2 16.0 16.5 19.0 12.9 13.8 25.0 17.6 22.5 17.6 17.4 21.2 69.1 73.7 19.8 27.1 14.3 19.1 12.9 27.6 5.2 2.2 23.5 16.3 5.0 10.0 17.1 58.8 16.7 6.7 16.8 19.3 0.0 37.3 1.6 6.2 15.4 45.0 21.0 12.6 0.4 21.7 30.5 13.7 25.0 9.9 8.8 0.7 55.3 22.0 23.6 3.3 0.5 29.5 10.2 16.8 19.0 1.0 5.6 21.8 16.0 21.5 15.6 1.5 3.1 16.6 5.0 85.9 18.0 2.6 30.8 48.3 8.1 5.5 9.7 4.1 0.0 30.3 9.0 0.3 2.0 18.9 15.9 5.1 21.6 5.6 12.0 21.8 PIEZO2 "C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771" ENSG00000154864 "Piezo type mechanosensitive ion channel component 2" Q9H5I5 18 10666483-11149569 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 58.3" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 399.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.1;BJ hTERT+ SV40 Large T+: 16.9;BJ hTERT+ SV40 Large T+ RasG12V: 23.1;HeLa: 38.1;U-266/70: 23.0;U-698: 16.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA015986, HPA031974, HPA040616" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA015986: AB_1848395, HPA031974: AB_10603675, HPA040616: AB_2677043" "unprognostic (1.36e-1)" "unprognostic (1.92e-1)" "unprognostic (9.21e-2)" "unprognostic (2.53e-2)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.87e-2)" "unprognostic (4.34e-3)" "unprognostic (6.55e-2)" "unprognostic (3.89e-2)" "unprognostic (6.06e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.57e-7)" "unprognostic (1.12e-3)" "unprognostic (1.09e-1)" "unprognostic (9.04e-2)" "unprognostic (1.83e-2)" 1.2 0.5 7.3 1.3 20.2 0.4 1.7 14.7 14.4 1.0 0.1 3.9 0.3 0.6 1.6 5.1 1.1 5.3 0.3 7.9 8.7 1.1 4.1 6.6 0.9 18.2 14.4 0.7 1.8 0.5 0.9 0.0 18.2 3.0 1.4 0.1 0.3 2.9 0.1 1.1 1.1 2.1 8.5 2.7 1.6 1.2 16.8 0.8 1.5 0.2 0.6 5.3 0.7 58.3 0.0 1.8 15.1 0.0 0.0 0.0 0.0 0.8 4.4 16.9 23.1 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 10.6 0.0 0.5 0.0 38.1 8.8 5.2 0.0 0.1 0.1 0.3 4.3 1.2 0.1 5.2 0.6 0.0 0.3 2.7 0.0 0.3 0.0 4.5 6.7 0.0 0.0 0.0 7.0 0.0 5.3 12.7 0.0 0.1 0.0 0.8 6.7 0.0 4.5 0.0 0.0 5.8 0.3 0.9 23.0 0.2 16.2 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 20.2 14.7 14.4 7.9 8.7 18.2 14.4 18.2 8.5 16.8 58.3 3.3 0.0 5.3 2.0 0.0 0.8 0.3 0.0 0.0 0.0 2.3 0.8 1.6 10.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 31.7 0.2 0.2 9.9 0.0 0.0 2.5 0.2 0.0 11.2 2.6 0.0 5.1 0.1 17.2 5.9 1.0 0.0 37.0 0.0 0.0 3.2 0.8 11.9 0.0 0.6 0.0 9.4 0.0 0.0 0.0 2.0 399.6 0.1 0.0 0.0 0.4 0.1 0.0 0.1 7.3 0.0 6.6 0.9 4.5 0.3 1.4 0.2 0.9 0.4 0.6 32.9 0.0 0.1 PIK3CA PI3K ENSG00000121879 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha" P42336 3 179148114-179240093 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Lipid metabolism, Phagocytosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 126.7;Inhibitory neurons: 122.0;Oligodendrocyte precursor cells: 130.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009985, CAB017804" Approved Supported Mitochondria,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Mitochondria "CAB017804: , HPA009985: AB_1079610" "unprognostic (1.81e-1)" "unprognostic (2.77e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-3)" "unprognostic (6.49e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-3)" "unprognostic (5.21e-2)" "unprognostic (4.50e-2)" "unprognostic (1.16e-2)" "unprognostic (2.48e-1)" "unprognostic (9.74e-2)" "unprognostic (3.82e-2)" 14.7 7.9 3.1 8.1 3.7 12.4 8.5 9.7 8.3 8.7 0.3 6.7 4.2 8.3 4.8 7.9 5.7 8.4 9.5 3.7 3.6 8.2 7.1 7.9 9.2 5.1 4.2 10.3 4.3 11.5 3.4 11.1 5.1 7.3 5.8 12.4 4.5 7.1 7.1 5.5 5.3 8.9 2.3 8.8 5.8 6.1 3.7 13.7 7.9 13.0 9.2 8.6 5.8 6.4 19.9 6.5 9.6 9.2 22.7 27.7 6.5 10.8 16.5 10.9 16.0 5.1 13.0 16.1 21.7 10.8 14.1 5.9 8.4 9.8 16.5 32.0 6.2 22.4 5.2 4.4 10.7 13.1 12.6 16.8 10.6 12.4 15.0 13.4 15.8 12.9 10.6 17.3 18.9 6.9 10.9 8.5 8.0 8.8 7.8 13.9 10.0 16.7 8.5 10.0 5.2 9.9 13.1 10.8 16.1 9.1 19.0 11.1 21.1 10.4 6.5 18.1 13.3 9.3 13.8 29.0 11.3 9.6 5.4 1.3 1.2 0.4 1.2 1.0 0.8 1.5 0.8 0.6 0.8 1.6 1.0 0.8 2.2 0.7 0.9 0.9 0.8 0.3 3.1 3.7 9.7 8.3 3.7 3.6 5.1 4.2 5.1 2.3 3.7 6.4 31.3 32.1 26.8 60.7 28.3 14.7 17.9 11.2 2.2 27.9 14.4 15.2 18.5 5.7 15.9 7.3 31.3 10.2 17.9 8.7 1.9 10.7 2.0 14.1 21.7 25.6 2.4 9.2 126.7 13.9 6.1 23.5 8.6 21.6 31.6 19.9 33.5 21.9 11.1 38.7 122.0 10.3 14.2 23.5 24.3 3.4 32.6 20.9 14.2 75.9 24.5 17.4 18.6 130.2 84.2 16.9 10.8 39.5 15.1 34.6 9.5 14.8 20.1 27.1 26.3 25.7 28.6 11.8 10.2 9.8 14.9 8.8 19.9 19.6 9.2 32.0 PIK3R1 "GRB1, p85, p85-ALPHA" ENSG00000145675 "Phosphoinositide-3-kinase regulatory subunit 1" P27986 5 68215756-68301821 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Protein transport, Stress response, Transport" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "dendritic cells: 410.2;Endometrial stromal cells: 479.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 265.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001216, CAB004268" Approved Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB004268: AB_628126, HPA001216: AB_1079612" "unprognostic (5.74e-2)" "unprognostic (6.58e-2)" "unprognostic (2.01e-1)" "unprognostic (1.31e-2)" "unprognostic (1.18e-1)" "unprognostic (1.33e-2)" "prognostic favorable (8.09e-4)" "unprognostic (3.78e-3)" "unprognostic (1.78e-1)" "unprognostic (2.71e-1)" "unprognostic (6.10e-2)" "unprognostic (1.32e-1)" "unprognostic (4.59e-3)" "unprognostic (5.66e-3)" "unprognostic (1.27e-1)" "unprognostic (5.92e-2)" "unprognostic (1.54e-1)" 60.6 27.3 13.6 27.8 33.3 126.4 92.1 12.5 40.8 51.2 0.6 38.2 17.2 65.8 45.0 43.2 69.0 35.0 72.3 29.9 13.0 35.9 100.8 26.7 28.5 11.2 22.1 53.3 13.4 40.2 7.3 32.4 12.0 26.7 22.2 59.9 64.5 31.9 63.5 28.7 24.5 74.8 9.9 38.1 18.3 8.6 20.3 46.5 20.6 33.9 23.7 27.0 31.7 36.0 4.3 8.2 23.8 71.4 265.5 76.9 10.4 23.2 10.6 8.8 9.4 20.4 7.4 21.8 38.5 32.0 4.3 10.2 6.7 46.9 11.0 90.6 8.9 26.1 6.5 17.0 89.2 27.0 20.1 81.9 104.2 16.1 83.6 4.1 11.7 25.0 4.1 16.1 8.1 11.3 65.7 10.5 6.9 14.7 4.3 61.1 11.3 17.0 11.5 47.9 4.7 21.3 4.0 6.3 15.0 13.7 34.3 19.0 14.0 10.3 10.4 17.3 14.8 18.0 29.2 25.2 11.1 32.9 7.8 22.0 1.7 8.8 11.5 2.4 16.6 1.7 14.9 11.1 3.0 3.9 18.6 14.1 2.2 11.7 6.5 1.2 12.3 5.5 13.6 33.3 12.5 40.8 29.9 13.0 11.2 22.1 12.0 9.9 20.3 36.0 47.7 51.3 24.8 112.3 47.7 14.4 23.5 30.8 175.2 46.0 61.4 168.4 263.0 38.6 19.3 5.5 25.0 13.4 410.2 28.4 72.4 15.8 12.6 38.7 479.9 39.0 9.6 43.5 232.8 9.5 18.5 151.0 43.8 93.2 68.9 110.4 31.1 198.3 30.7 48.8 82.7 32.6 28.5 69.2 24.7 11.9 172.1 68.8 33.8 117.1 37.6 194.1 137.0 281.5 199.9 12.3 19.8 122.2 173.2 8.4 24.3 39.1 8.7 89.4 19.7 127.2 76.5 1.7 4.5 37.2 10.2 10.0 309.9 45.4 36.5 8.1 PIK3R2 "p85, P85B" ENSG00000105647 "Phosphoinositide-3-kinase regulatory subunit 2" O00459 19 18153163-18170532 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Stress response, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 14.4;Undifferentiated cells: 16.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" HPA069291 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA069291: AB_2686109" "unprognostic (2.50e-1)" "unprognostic (1.90e-3)" "unprognostic (1.68e-2)" "unprognostic (1.87e-1)" "unprognostic (2.00e-2)" "unprognostic (9.65e-3)" "unprognostic (1.69e-3)" "unprognostic (2.36e-3)" "unprognostic (9.24e-2)" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (3.36e-1)" "unprognostic (1.69e-2)" "unprognostic (2.02e-1)" "unprognostic (6.35e-3)" "unprognostic (8.63e-2)" "unprognostic (2.00e-2)" 7.2 25.6 26.2 6.9 22.9 9.7 7.6 1.1 41.5 17.6 2.0 13.4 20.5 17.5 12.0 26.0 16.7 12.3 12.8 41.0 6.7 9.5 10.5 9.1 5.2 4.4 7.1 21.5 11.0 20.8 21.5 8.7 4.9 15.5 9.6 7.9 15.0 10.4 12.4 26.3 16.7 9.8 4.7 8.7 15.1 11.5 9.4 11.6 10.5 9.9 6.2 15.3 15.3 16.4 39.1 18.0 25.4 36.8 35.3 36.6 40.5 29.4 38.3 21.6 16.6 18.3 20.4 28.0 48.8 41.9 17.5 28.7 15.6 33.2 11.3 25.0 65.5 10.8 21.3 44.0 29.7 24.6 13.4 45.7 36.4 15.0 21.5 36.8 6.6 11.9 33.6 10.8 30.3 57.0 21.5 17.0 32.9 35.8 48.5 19.6 33.4 23.5 37.7 22.8 63.0 68.0 27.1 28.5 28.9 16.0 19.1 15.8 11.4 40.9 20.8 49.2 27.5 22.9 26.4 10.9 33.9 39.4 26.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 26.2 22.9 1.1 41.5 41.0 6.7 4.4 7.1 4.9 4.7 9.4 16.4 1.0 6.4 1.1 7.2 0.8 1.9 1.3 1.0 1.8 6.3 3.6 3.2 1.5 2.8 1.0 3.7 4.2 1.7 0.8 6.9 0.0 6.0 0.3 1.3 1.7 0.8 6.1 7.4 11.7 6.2 2.9 1.7 1.1 0.8 2.5 1.4 1.4 1.3 2.2 10.1 11.2 10.5 0.0 4.7 1.0 0.0 1.8 1.7 0.0 3.7 1.6 5.7 0.0 10.6 9.2 6.4 7.0 1.9 0.9 1.1 14.4 1.1 0.5 4.3 0.0 1.4 1.4 0.5 2.1 1.3 2.3 1.2 0.9 3.2 16.4 0.6 PIP5K1C "KIAA0589, LCCS3, PIP5Kgamma" ENSG00000186111 "Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma" O60331 19 3630183-3700468 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Chemotaxis, Endocytosis, Exocytosis, Phagocytosis" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Bipolar cells: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "U-2197: 75.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017168 Approved Approved Nucleoplasm,Cytosol No No "Cluster 10: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "HPA017168: AB_1855395" "unprognostic (1.20e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.36e-3)" "prognostic favorable (7.28e-5)" "unprognostic (7.03e-2)" "unprognostic (4.02e-3)" "unprognostic (5.80e-3)" "unprognostic (8.50e-2)" "unprognostic (1.31e-1)" "unprognostic (2.57e-3)" "prognostic favorable (2.32e-4)" "unprognostic (1.51e-1)" "prognostic favorable (3.00e-4)" "unprognostic (2.25e-1)" "unprognostic (1.84e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" 22.1 15.6 30.7 11.5 36.6 3.4 19.2 19.4 66.4 24.0 0.0 62.2 8.6 44.9 7.6 20.3 29.8 8.2 32.2 40.2 5.0 15.8 8.7 22.6 6.5 13.3 7.7 22.2 18.0 10.7 20.6 11.2 12.9 33.9 4.5 13.2 18.1 25.1 17.7 16.0 24.1 16.0 0.0 22.4 29.7 61.4 19.5 5.3 21.1 4.8 4.2 39.4 24.7 33.2 18.9 18.0 13.4 18.0 25.5 21.0 20.3 36.1 22.4 15.2 12.3 16.1 5.2 7.8 13.6 39.0 16.5 16.4 6.5 11.7 6.2 28.7 11.9 9.0 15.0 13.1 22.0 9.4 26.7 23.7 9.9 12.4 4.1 9.9 25.6 11.5 14.1 13.5 14.4 15.7 11.2 6.6 14.4 6.8 24.6 21.4 7.2 11.2 11.5 15.9 13.7 12.0 18.7 10.1 11.1 16.6 7.9 14.1 57.3 21.3 11.8 75.1 17.0 16.0 14.3 3.5 27.6 19.2 15.0 1.0 0.7 0.0 0.7 0.5 0.2 0.6 0.5 0.4 0.8 0.3 0.2 0.4 0.5 0.5 0.8 0.5 0.4 0.6 30.7 36.6 19.4 66.4 40.2 5.0 13.3 7.7 12.9 0.0 19.5 33.2 20.3 6.4 5.0 8.8 6.2 5.4 3.0 6.1 7.4 56.8 9.6 6.6 7.5 7.2 3.0 16.5 37.5 7.8 10.6 12.2 1.9 7.9 11.6 6.4 29.0 22.1 8.4 2.1 30.6 7.1 7.4 10.7 7.1 11.6 1.3 10.7 16.1 4.0 15.7 30.3 17.9 9.7 6.1 19.6 13.2 24.0 14.9 15.5 5.4 22.5 15.0 14.3 11.3 9.0 6.8 12.1 13.2 24.0 5.7 4.4 7.2 6.4 4.1 26.8 13.1 8.4 10.4 18.6 11.8 7.8 6.8 16.4 8.0 11.9 7.2 5.3 PITX1 "BFT, POTX, PTX1" ENSG00000069011 "Paired like homeodomain 1" P78337 5 135027734-135034813 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 711.6;vagina: 199.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 121.0;Basal squamous epithelial cells: 409.2;Squamous epithelial cells: 1069.0;Urothelial cells: 257.3" "Cancer enhanced" "Detected in many" "cervical cancer: 73.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 141.4;HeLa: 108.9;K-562: 112.1;T-47d: 157.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA008743 Approved Approved Nucleoli Yes No "Cluster 84: Esophagus - Epithelial cell function" "Cluster 39: CACO-2 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoli "HPA008743: AB_1855413" "unprognostic (1.84e-1)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (4.62e-2)" "unprognostic (5.08e-2)" "unprognostic (5.26e-3)" "unprognostic (1.03e-2)" "unprognostic (1.66e-2)" "unprognostic (5.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.60e-2)" "unprognostic (2.27e-1)" "unprognostic (5.80e-14)" "unprognostic (6.22e-2)" "unprognostic (1.33e-1)" "unprognostic (5.98e-3)" "unprognostic (4.97e-3)" 1.5 1.9 0.7 7.7 0.6 0.3 0.6 0.9 0.7 83.5 4.7 11.4 12.1 0.8 0.0 711.6 0.5 1.1 0.2 0.9 1.1 0.1 0.3 0.4 0.1 0.8 0.9 0.6 0.4 0.0 164.7 2.7 0.7 20.1 2.0 0.1 137.5 0.0 14.1 2.0 7.9 0.4 0.5 0.2 41.9 2.2 0.7 0.0 0.2 20.1 12.6 85.0 199.0 0.8 57.5 36.9 0.0 44.7 1.4 0.9 13.4 9.6 14.6 5.1 2.3 141.4 32.5 59.9 17.6 0.9 12.6 17.6 6.4 25.5 0.3 0.7 48.2 13.4 108.9 38.4 15.6 5.8 0.1 1.4 18.4 0.0 4.9 0.3 0.1 10.1 112.1 0.2 1.9 18.4 0.6 12.3 0.1 4.8 31.8 18.5 1.1 1.2 0.6 17.9 20.2 0.1 48.4 24.1 0.0 0.5 157.5 4.2 1.5 6.1 13.4 3.5 17.0 0.1 0.2 40.7 8.1 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.9 0.7 0.9 1.1 0.8 0.9 0.7 0.5 0.7 0.8 0.1 0.0 0.0 0.0 0.2 1.3 121.0 12.8 409.2 1.0 2.5 2.7 2.3 1.5 8.6 0.0 0.0 0.8 0.0 4.2 0.0 0.2 4.2 0.3 0.6 1.2 0.0 50.8 0.0 0.4 2.1 28.8 0.5 0.2 0.0 2.7 0.0 0.0 0.9 0.0 0.0 2.4 6.1 0.0 0.3 5.7 0.3 1.0 0.0 0.0 0.0 0.4 1.0 0.0 0.1 16.9 3.4 0.0 3.1 101.6 0.3 0.2 6.1 1.8 0.0 2.1 4.5 2.2 5.6 1069.0 6.8 7.7 0.9 0.7 2.5 257.3 PITX2 "ARP1, Brx1, IGDS, IHG2, IRID2, Otlx2, RGS, RIEG, RIEG1, RS" ENSG00000164093 "Paired like homeodomain 2" Q99697 4 110617423-110642123 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.0;skeletal muscle: 43.2;urinary bladder: 29.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 19.2;Fibroblasts: 69.6;Paneth cells: 20.6;Proximal enterocytes: 39.7;Skeletal myocytes: 49.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "hypothalamus: 17.8;thalamus: 6.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 24.8;HEK 293: 10.5;LHCN-M2: 25.1;RH-30: 20.5" "Group enriched" "Detected in some" 25 "hypothalamus: 5.4;midbrain: 1.5" "HPA050074, HPA062728" Enhanced Nucleoplasm NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA050074: AB_2681005, HPA062728: AB_2684851" "unprognostic (1.08e-1)" "unprognostic (1.23e-2)" "unprognostic (9.29e-2)" "unprognostic (9.24e-2)" "unprognostic (1.68e-1)" "unprognostic (1.14e-2)" "unprognostic (9.61e-4)" "unprognostic (3.22e-2)" "unprognostic (1.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.16e-1)" "unprognostic (2.77e-1)" "unprognostic (1.11e-15)" "unprognostic (6.97e-3)" "unprognostic (1.43e-1)" "unprognostic (5.98e-2)" "unprognostic (9.91e-2)" 0.2 0.0 0.0 7.8 0.2 0.0 0.4 0.0 0.0 1.6 0.0 3.8 0.0 0.1 0.0 2.6 0.2 1.1 2.0 0.0 17.8 0.2 0.0 0.0 0.0 0.1 2.8 0.0 0.5 0.0 16.1 42.0 0.2 0.9 0.2 0.0 13.5 0.1 43.2 1.5 3.1 0.5 0.2 0.0 0.5 0.5 6.8 0.0 0.0 12.3 0.0 29.8 3.8 0.0 1.4 2.6 0.0 1.0 2.4 2.1 4.0 0.8 0.4 2.6 2.0 24.8 0.0 0.0 5.2 5.1 3.2 0.4 0.1 0.0 1.4 0.0 10.5 0.0 2.0 0.0 8.8 0.0 5.0 2.5 0.2 0.5 0.0 0.8 0.0 2.7 0.6 0.0 25.1 0.7 2.7 0.0 0.4 0.0 0.5 0.0 20.5 0.0 0.4 3.4 0.0 0.0 2.0 3.3 0.3 0.4 0.2 0.0 0.0 3.1 7.5 0.0 4.1 0.1 0.1 1.0 1.8 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 17.8 0.1 2.8 0.2 0.2 6.8 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.6 0.0 1.2 0.0 0.1 0.3 19.2 0.0 0.1 0.0 0.0 5.8 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.5 1.8 0.0 0.0 0.4 5.7 69.6 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 9.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 0.2 39.7 2.3 0.0 0.0 0.0 49.8 5.4 2.3 7.0 1.7 0.1 10.5 0.0 0.0 14.1 0.1 PITX3 ASMD ENSG00000107859 "Paired like homeodomain 3" O75364 10 102230186-102241512 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 5.5;skeletal muscle: 16.5;tongue: 6.0" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 22.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "midbrain: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "RH-30: 30.3" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 9.1" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.13e-2)" "unprognostic (4.07e-1)" "unprognostic (5.15e-3)" "unprognostic (6.30e-2)" "unprognostic (1.06e-1)" "unprognostic (6.04e-5)" "unprognostic (6.30e-3)" "unprognostic (2.02e-1)" "unprognostic (6.36e-2)" "unprognostic (2.67e-2)" "unprognostic (3.73e-2)" "unprognostic (1.76e-2)" "unprognostic (6.76e-3)" "unprognostic (4.13e-2)" 1.2 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.1 0.2 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 16.5 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.2 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.0 5.5 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 22.1 0.3 1.4 1.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 PKD1 "PBP, Pc-1, TRPP1" ENSG00000008710 "Polycystin 1, transient receptor potential channel interacting" P98161 16 2088708-2135898 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 72.4" "Cell type enhanced" "Detected in all" "Excitatory neurons: 138.1;Horizontal cells: 119.5;Inhibitory neurons: 101.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 65.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046448 Approved NA NA 840000 "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" "CAB046448: AB_2163360" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (7.43e-4)" "unprognostic (1.35e-1)" "unprognostic (1.79e-1)" "prognostic favorable (3.35e-4)" "unprognostic (1.98e-2)" "unprognostic (1.02e-2)" "unprognostic (1.81e-1)" "unprognostic (1.22e-2)" "prognostic favorable (3.38e-5)" "unprognostic (7.86e-2)" "unprognostic (4.07e-1)" "unprognostic (3.44e-2)" "unprognostic (1.19e-1)" "unprognostic (1.78e-2)" "unprognostic (2.81e-1)" 14.8 9.5 7.9 4.9 10.4 3.9 13.7 65.4 32.1 22.1 0.0 40.3 3.8 30.6 2.0 11.3 25.9 3.7 23.9 9.6 1.6 7.5 8.9 13.4 3.4 16.2 1.7 23.8 10.4 2.3 72.4 3.7 12.6 19.9 1.5 7.4 10.4 8.7 47.7 16.8 15.3 6.1 0.1 9.9 19.1 10.3 4.7 2.8 10.3 8.3 1.5 24.5 15.5 4.9 4.2 8.9 4.8 10.9 8.2 8.8 9.3 14.2 5.9 4.0 4.0 8.0 3.1 6.3 8.9 7.3 4.3 10.4 1.4 2.1 1.5 7.4 7.1 3.9 25.8 3.2 16.1 5.4 7.8 8.2 7.0 7.5 4.6 5.6 3.1 6.6 5.7 6.2 2.6 6.9 7.7 16.5 4.3 1.7 6.6 21.6 7.7 9.6 2.1 2.8 19.9 22.2 12.9 8.5 8.9 1.7 7.0 18.3 7.4 12.7 10.3 9.6 10.5 9.0 4.3 7.0 7.1 5.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 10.4 65.4 32.1 9.6 1.6 16.2 1.7 12.6 0.1 4.7 4.9 21.3 12.8 12.2 61.7 6.9 24.3 10.3 14.7 30.7 79.8 15.4 18.9 26.4 4.3 10.9 9.2 41.7 6.0 11.2 13.6 9.8 5.2 51.9 16.0 32.1 17.1 30.5 4.8 138.1 3.1 4.0 30.4 8.2 16.9 8.2 21.3 15.7 24.2 5.2 119.5 101.0 17.6 4.1 7.2 12.6 10.6 27.7 7.8 23.2 18.7 6.2 36.4 11.3 38.2 29.5 4.5 5.9 45.9 9.0 10.3 8.9 7.7 32.9 35.2 32.9 41.4 25.2 10.1 15.8 26.0 20.0 3.1 10.9 10.1 14.2 6.9 PKD1L1 PRO19563 ENSG00000158683 "Polycystin 1 like 1, transient receptor potential channel interacting" Q8TDX9 7 47740202-47948466 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" Heterotaxy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Adipocytes: 9.1;Astrocytes: 13.4;Early spermatids: 11.8;Excitatory neurons: 25.7;Inhibitory neurons: 37.9;Microglial cells: 15.0;Oligodendrocyte precursor cells: 11.6;Oligodendrocytes: 17.1" "Cancer enhanced" "Detected in single" "testis cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "T-47d: 5.9;U-266/70: 14.7;U-266/84: 5.7" "Not detected" "Not detected" "HPA020422, HPA022424" Uncertain NA NA "Cluster 11: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA020422: AB_1855434, HPA022424: AB_1855435" "unprognostic (5.47e-2)" "unprognostic (5.33e-3)" "unprognostic (1.49e-2)" "unprognostic (9.74e-2)" "unprognostic (4.03e-2)" "unprognostic (6.31e-2)" "unprognostic (2.52e-2)" "unprognostic (1.11e-1)" "unprognostic (9.63e-3)" "unprognostic (7.96e-2)" "unprognostic (1.78e-2)" "unprognostic (2.21e-1)" "unprognostic (1.88e-4)" "unprognostic (1.88e-3)" "unprognostic (2.56e-1)" "unprognostic (2.50e-1)" "unprognostic (1.90e-1)" 1.7 0.1 1.1 0.4 0.9 1.1 0.5 2.1 1.9 0.2 0.0 0.4 0.9 0.3 0.6 0.4 0.3 0.4 2.6 0.4 1.3 0.3 0.8 0.4 0.9 0.5 0.7 0.3 0.3 0.1 0.4 0.6 0.7 0.3 0.5 1.7 0.4 0.1 2.8 0.5 0.4 0.4 0.1 0.3 0.4 1.5 0.8 1.5 0.4 3.3 0.6 0.6 0.1 1.1 0.4 0.7 0.6 0.8 0.1 0.0 1.2 0.3 0.2 0.2 0.4 0.8 0.4 0.3 0.3 0.4 0.4 0.8 0.5 0.6 0.6 0.2 0.4 0.3 0.3 0.8 0.0 0.5 0.3 0.2 0.1 0.3 0.2 0.2 1.1 0.4 0.4 1.1 0.5 0.2 0.3 0.3 0.4 0.0 0.2 0.2 0.3 0.3 0.1 0.7 0.5 0.4 0.5 0.3 0.4 0.5 5.9 0.1 0.1 0.5 1.1 0.2 0.3 14.7 5.7 0.5 0.2 0.2 0.3 0.9 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.2 0.1 0.1 1.1 0.9 2.1 1.9 0.4 1.3 0.5 0.7 0.7 0.1 0.8 1.1 9.1 0.0 0.0 13.4 0.3 0.1 0.0 0.0 0.0 3.1 0.1 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.8 0.5 0.1 3.7 0.0 0.0 25.7 0.2 0.2 1.7 0.0 0.3 0.0 0.2 2.2 0.1 1.4 1.7 37.9 0.7 0.0 0.3 0.0 5.3 0.3 0.2 0.0 15.0 0.0 0.5 0.0 11.6 17.1 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 1.5 0.0 0.4 0.2 1.4 0.6 0.0 0.0 0.0 0.1 0.3 0.8 0.0 PKD2 "Pc-2, PC2, PKD4, TRPP2" ENSG00000118762 "Polycystin 2, transient receptor potential cation channel" Q13563 4 88007635-88077777 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Potassium transport, Transport, Wnt signaling pathway" "Calcium channel, Ion channel, Potassium channel, Voltage-gated channel" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 129.1;Inhibitory neurons: 148.6;Microglial cells: 95.5;Oligodendrocyte precursor cells: 178.9;Oligodendrocytes: 219.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 137.2;BJ hTERT+: 207.1;fHDF/TERT166: 166.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004544, HPA015794, HPA055297" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" Cytosol "CAB004544: AB_672377, HPA015794: AB_1855437, HPA055297: " "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (1.22e-1)" "unprognostic (6.83e-2)" "unprognostic (9.71e-2)" "unprognostic (1.97e-1)" "unprognostic (3.17e-2)" "unprognostic (1.88e-1)" "unprognostic (8.64e-2)" "unprognostic (1.08e-1)" "unprognostic (6.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.17e-3)" "unprognostic (3.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.12e-2)" "unprognostic (2.51e-1)" 30.7 24.2 9.6 13.9 12.2 10.7 18.6 10.0 12.0 40.0 7.3 32.5 10.7 61.1 14.7 12.7 39.3 26.9 19.7 9.0 8.9 48.6 15.0 22.2 11.5 10.4 11.2 47.7 14.8 27.9 9.0 24.5 10.0 23.3 13.2 14.0 9.7 39.2 5.8 10.3 14.8 53.7 9.1 10.9 20.0 10.3 11.9 7.6 16.4 11.7 8.7 20.6 18.4 14.6 7.4 40.8 44.9 23.2 101.8 67.6 13.3 137.2 207.1 62.9 62.2 2.0 12.8 4.0 29.3 166.4 24.0 9.1 8.1 20.4 54.5 21.2 7.1 6.6 21.8 4.3 56.5 16.2 12.9 56.4 9.1 49.4 26.4 85.6 28.8 7.6 0.9 10.9 55.5 14.4 11.4 7.7 23.4 5.3 6.7 21.5 26.8 6.0 55.6 17.2 9.0 20.1 25.5 1.2 32.5 45.0 9.7 12.1 44.7 59.1 12.9 16.8 18.8 8.7 2.9 4.4 35.2 2.5 55.3 1.4 0.1 0.2 0.2 0.2 0.4 0.1 0.2 0.1 0.0 0.1 0.2 0.1 0.2 0.3 0.1 0.4 0.1 0.1 9.6 12.2 10.0 12.0 9.0 8.9 10.4 11.2 10.0 9.1 11.9 14.6 14.8 3.2 6.3 59.4 3.5 7.4 5.3 7.4 23.3 16.7 7.4 11.3 7.1 18.6 7.2 69.9 10.4 10.4 2.7 0.6 0.0 14.0 0.3 10.3 41.7 19.2 6.7 13.5 129.1 3.8 3.4 42.0 2.0 11.1 1.3 12.7 21.4 10.6 12.2 26.9 148.6 3.4 4.1 5.0 6.8 1.1 23.0 9.8 23.2 95.5 9.5 17.3 4.1 178.9 219.4 2.2 4.6 50.8 3.1 6.5 3.9 17.0 12.3 1.9 26.3 53.0 31.5 0.8 3.8 13.3 6.7 2.7 6.1 11.5 2.8 3.4 PKHD1 "ARPKD, FCYT, FPC, TIGM1" ENSG00000170927 "PKHD1 ciliary IPT domain containing fibrocystin/polyductin" P08F94 6 51615299-52087613 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 4.7;kidney: 13.6;pancreas: 9.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 60.1;Collecting duct cells: 46.0;Early spermatids: 293.6;Late spermatids: 83.1" "Group enriched" "Detected in some" 5 "pancreatic cancer: 1.4;renal cancer: 5.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "RPTEC TERT1: 10.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA031227 Enhanced "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 29: Early spermatids - Spermatogenesis" "HPA031227: AB_10602068" "unprognostic (6.34e-3)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" "unprognostic (1.35e-1)" "unprognostic (3.80e-2)" "unprognostic (1.29e-2)" "unprognostic (4.03e-2)" "unprognostic (6.42e-2)" "unprognostic (7.08e-2)" "unprognostic (2.44e-2)" "unprognostic (1.02e-2)" "unprognostic (2.62e-2)" "prognostic favorable (9.74e-8)" "unprognostic (2.33e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.48e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.1 1.1 0.0 0.0 0.0 13.6 1.5 0.0 0.0 0.1 0.1 0.0 9.4 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.3 10.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.3 1.4 60.1 0.0 46.0 0.0 0.1 0.0 0.1 1.9 18.2 293.6 0.2 0.0 0.3 0.0 0.0 3.2 0.9 0.1 0.1 2.6 0.4 0.0 0.0 0.0 3.7 0.1 0.0 2.8 0.0 0.0 0.0 0.0 83.1 2.1 0.5 5.4 0.0 0.0 3.1 0.0 0.5 0.7 2.6 0.0 0.4 0.0 0.4 0.0 23.3 0.0 0.1 0.0 0.0 0.1 15.0 1.7 0.0 0.0 0.0 0.3 0.0 0.1 0.8 PKP1 B6P ENSG00000081277 "Plakophilin 1" Q13835 1 201283452-201332993 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Developmental protein" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 416.7;skin 1: 699.9;vagina: 200.4" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 139.7;Squamous epithelial cells: 234.5;Suprabasal keratinocytes: 409.0" "Group enriched" "Detected in many" 4 "cervical cancer: 125.5;head and neck cancer: 295.4;lung cancer: 79.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 234.6;HBEC3-KT: 144.2;hTCEpi: 501.4;hTERT-HME1: 132.5;PC-3: 192.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA027221, CAB033130" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 2500000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Plasma membrane" "CAB033130: AB_2164139, HPA027221: AB_10599737" "unprognostic (3.55e-3)" "unprognostic (7.63e-2)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-2)" "unprognostic (2.40e-2)" "unprognostic (3.48e-2)" "unprognostic (1.49e-1)" "unprognostic (5.02e-2)" "unprognostic (2.20e-3)" "unprognostic (2.67e-1)" "unprognostic (9.17e-3)" "unprognostic (2.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-1)" "unprognostic (6.59e-3)" 9.7 0.2 0.3 0.2 0.2 0.2 31.7 0.0 1.1 102.9 0.0 0.4 0.2 0.2 3.3 416.7 1.0 0.1 0.6 0.2 0.0 0.4 0.3 5.0 0.2 0.0 1.1 0.2 0.5 0.0 0.6 5.5 0.5 32.3 0.2 32.4 60.5 9.1 6.6 699.9 0.6 0.0 0.0 0.1 0.4 0.2 0.0 23.7 0.5 2.9 48.0 3.2 200.4 0.0 49.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 1.1 0.0 0.2 0.1 0.0 234.6 0.0 144.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 501.4 5.6 132.5 0.0 0.0 0.1 0.0 0.2 0.0 38.4 0.0 0.1 0.0 0.0 192.6 0.0 0.4 0.0 0.0 1.1 0.0 0.0 18.3 4.4 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 1.1 0.2 0.0 0.0 1.1 0.5 0.0 0.0 0.0 39.9 0.0 0.0 0.3 0.0 139.7 58.2 57.1 63.7 34.7 7.7 17.9 1.9 0.0 20.0 0.0 2.1 0.1 0.1 0.1 0.0 2.5 0.1 0.2 0.1 4.1 0.0 0.0 0.6 1.1 0.1 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 5.0 0.1 1.6 4.1 0.0 16.5 0.8 0.0 0.4 16.0 0.0 0.0 5.2 0.0 0.0 0.1 16.1 0.1 0.0 0.0 25.7 0.2 0.1 2.8 37.4 0.0 6.1 2.0 0.0 0.1 234.5 409.0 0.1 1.1 0.0 0.1 47.5 PLCB4 ENSG00000101333 "Phospholipase C beta 4" Q15147 20 9068763-9481242 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.6;salivary gland: 57.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 105.9;Horizontal cells: 164.9;Inhibitory neurons: 113.8;Microglial cells: 183.6;Oligodendrocyte precursor cells: 168.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.5" "Region enhanced" "Detected in all" "cerebellum: 55.6" "Immune cell enriched" "Detected in single" 18 "plasmacytoid DC: 3.0" "Lineage enriched" "Detected in single" 18 "dendritic cells: 3.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 91.4;hTERT-HME1: 45.9;LHCN-M2: 77.6;OE19: 48.2;RPTEC TERT1: 96.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007951 Approved Approved Nucleoplasm,Microtubules NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 21: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Microtubules Nucleoplasm "HPA007951: AB_2667944" "unprognostic (3.88e-2)" "unprognostic (3.62e-1)" "unprognostic (1.19e-2)" "prognostic favorable (2.11e-4)" "unprognostic (1.44e-2)" "unprognostic (9.72e-3)" "unprognostic (3.32e-3)" "unprognostic (2.57e-2)" "unprognostic (7.75e-2)" "unprognostic (4.23e-2)" "unprognostic (5.21e-3)" "unprognostic (1.35e-1)" "unprognostic (4.64e-3)" "unprognostic (7.12e-2)" "unprognostic (1.37e-1)" "unprognostic (2.22e-1)" "unprognostic (4.45e-2)" 6.3 7.2 8.6 3.4 3.7 0.5 7.0 55.6 6.3 4.6 31.0 20.5 2.6 8.2 24.4 9.0 15.0 5.9 17.9 2.5 10.8 3.0 0.3 5.4 1.7 13.4 17.8 2.1 2.1 0.7 8.2 6.5 12.0 9.7 17.9 15.1 57.4 6.1 2.7 4.6 4.2 9.1 5.3 1.3 14.4 2.4 23.3 4.5 32.7 6.8 2.3 8.2 5.3 6.5 0.0 15.1 7.9 0.0 0.0 0.4 0.1 35.8 9.5 10.9 6.1 3.4 2.6 0.0 0.6 91.4 39.0 0.1 2.3 7.6 14.7 0.0 5.3 3.8 5.7 0.0 1.6 0.0 0.0 2.3 3.0 12.7 45.9 18.7 0.1 0.0 4.3 0.4 77.6 5.0 0.0 0.0 8.8 48.2 10.4 0.0 0.0 0.7 96.9 5.8 25.5 18.4 0.0 23.8 15.1 10.5 19.2 0.2 0.5 11.2 0.9 1.2 14.2 0.0 0.0 0.0 1.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.0 8.6 3.7 55.6 6.3 2.5 10.8 13.4 17.8 12.0 5.3 23.3 6.5 37.8 6.4 0.5 60.1 0.3 2.4 3.8 1.5 2.2 82.9 5.7 5.3 72.6 0.0 8.9 5.5 0.0 0.0 4.5 17.9 0.0 0.7 1.4 46.2 4.6 40.4 42.0 0.0 105.9 0.2 0.0 9.0 18.8 53.5 0.0 36.6 1.8 0.0 0.1 164.9 113.8 36.4 14.2 0.0 2.1 1.2 1.5 0.8 7.2 183.6 0.6 2.9 0.0 168.9 2.9 7.1 9.7 20.7 0.2 8.5 2.1 1.2 39.5 6.6 13.1 10.5 36.0 1.5 2.0 0.5 1.0 0.1 1.4 4.8 40.4 2.5 PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600404-171810950 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 519.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 57.5;SK-MEL-30: 31.1;TIME: 50.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004527, HPA042396, HPA066938" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "CAB004527: AB_677324, HPA042396: AB_2677977, HPA066938: " "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.76e-6)" 7.8 26.4 9.2 6.6 24.7 7.8 7.5 18.4 13.6 10.4 4.5 14.6 46.9 6.2 2.8 33.0 6.4 86.8 24.4 10.5 14.3 12.0 33.7 4.7 9.1 24.8 22.0 24.2 21.2 1.6 2.3 10.7 23.5 3.4 14.7 0.5 13.8 6.0 2.5 29.2 43.9 4.8 14.7 15.7 8.2 5.0 19.0 4.1 3.7 6.8 10.8 5.1 12.4 41.4 4.5 7.2 3.7 1.4 11.2 12.6 7.7 2.3 9.9 3.5 4.3 1.1 6.4 0.0 17.0 0.9 24.0 15.2 0.6 2.0 5.7 3.6 3.2 4.2 11.5 26.1 4.9 7.3 18.9 4.9 10.9 4.2 2.0 10.0 57.5 1.2 2.8 0.0 0.9 1.3 0.0 6.4 0.8 11.9 5.1 0.2 1.5 0.1 8.9 1.8 0.1 0.1 7.9 4.7 31.1 5.1 9.0 9.7 50.7 1.5 5.7 4.0 2.5 9.6 8.2 0.1 6.7 8.6 1.9 8.3 1.8 2.3 0.3 1.1 2.6 0.0 0.2 0.6 0.6 0.0 0.0 0.1 1.0 2.2 0.4 0.0 0.8 0.6 9.2 24.7 18.4 13.6 10.5 14.3 24.8 22.0 23.5 14.7 19.0 41.4 7.7 0.0 4.7 2.0 0.9 7.1 3.4 11.0 10.8 0.4 4.9 5.6 33.6 57.2 11.1 1.8 0.0 3.0 1.9 37.5 3.9 8.4 13.1 1.0 4.8 7.4 4.2 6.3 8.9 3.4 3.7 15.7 27.0 1.3 27.9 10.4 6.4 15.9 20.0 0.0 12.1 23.6 6.1 13.2 2.4 9.5 10.5 10.2 12.4 98.4 5.4 0.0 1.0 12.5 519.6 2.4 18.3 4.5 3.4 0.7 38.3 48.0 9.9 0.1 19.7 3.8 8.4 6.1 5.3 93.5 34.9 2.3 2.3 12.1 17.8 4.7 PLEC "EBS1, PCN, PLEC1, PLTN" ENSG00000178209 Plectin Q15149 8 143915153-143976734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant, Epidermolysis bullosa, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 256.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "PC-3: 384.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003847, HPA025967, HPA029906" Enhanced Supported "Intermediate filaments,Focal adhesion sites,Cytosol" NA NA 7400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Intermediate filaments, Cytosol" "Focal adhesion sites" "CAB003847: AB_562198, HPA025967: AB_10601671, HPA029906: AB_10602279" "unprognostic (1.02e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.72e-3)" "unprognostic (1.13e-2)" "unprognostic (2.85e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (7.98e-6)" "unprognostic (2.30e-1)" "unprognostic (4.04e-2)" "unprognostic (6.58e-2)" "unprognostic (5.58e-3)" 41.8 30.9 44.2 22.6 25.4 43.2 37.9 20.4 39.7 57.4 6.7 58.0 21.1 55.2 8.5 59.7 47.9 22.8 78.9 42.2 31.0 30.0 31.3 49.2 22.1 48.5 28.6 47.1 27.6 8.1 33.0 18.3 30.8 49.5 13.0 3.9 42.9 19.8 256.5 83.1 53.8 27.7 28.8 46.1 49.1 15.3 43.2 14.4 25.7 74.7 15.8 56.5 55.7 25.9 92.6 247.3 15.1 20.3 31.6 66.9 62.8 125.9 49.3 32.3 18.7 39.2 88.5 8.9 82.9 179.7 54.6 98.9 10.3 162.6 13.3 58.7 10.0 24.9 268.0 34.0 54.0 9.6 26.1 71.8 40.7 84.6 164.2 28.3 43.0 7.6 16.2 25.9 39.7 175.3 5.1 19.8 12.2 29.4 384.8 1.8 46.2 24.6 67.7 147.7 16.6 16.8 217.4 50.0 21.1 21.7 55.7 12.4 125.7 117.8 217.3 110.6 155.1 4.7 3.7 6.3 106.9 15.2 176.2 0.0 2.0 0.1 0.6 1.7 1.3 0.6 1.2 0.9 1.6 0.6 0.8 0.5 0.4 0.3 1.2 1.3 1.4 2.0 44.2 25.4 20.4 39.7 42.2 31.0 48.5 28.6 30.8 28.8 43.2 25.9 83.8 28.9 15.6 78.0 27.0 108.0 53.1 62.9 50.7 15.8 29.4 27.9 39.3 31.5 42.9 40.5 25.0 34.4 27.1 257.8 0.0 39.3 1.4 39.4 52.6 68.2 32.2 11.8 47.3 20.2 32.1 45.7 170.2 57.3 8.2 14.4 63.1 69.0 35.2 30.3 36.5 79.9 10.2 67.5 100.4 5.0 44.4 61.2 33.8 27.2 54.9 11.2 15.5 14.6 3.4 157.8 194.1 74.9 39.3 144.9 124.9 4.6 50.3 10.8 6.6 42.1 61.5 1.2 7.1 72.2 76.7 69.0 35.0 18.8 61.6 121.0 PLEKHM1 KIAA0356 ENSG00000225190 "Pleckstrin homology and RUN domain containing M1" Q9Y4G2 17 45435900-45490749 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 31.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.5" "Cell line enhanced" "Detected in many" "OE19: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025018, HPA039473" Approved Supported Nucleoli,Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles Nucleoli "HPA025018: AB_1855465, HPA039473: AB_2676526" "unprognostic (1.52e-1)" "unprognostic (3.13e-2)" "unprognostic (4.29e-2)" "prognostic favorable (1.28e-6)" "unprognostic (8.71e-2)" "unprognostic (3.06e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.20e-2)" "unprognostic (1.88e-1)" "unprognostic (2.93e-2)" "unprognostic (4.02e-1)" "unprognostic (3.93e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (1.60e-1)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" 7.0 6.4 2.9 5.5 2.9 9.7 6.2 3.5 3.8 12.9 3.2 6.5 3.5 5.7 1.0 31.7 5.9 5.3 6.2 2.8 3.1 3.6 3.6 8.8 4.8 3.7 3.1 4.9 6.1 4.4 5.7 2.9 3.2 5.1 3.6 1.6 14.4 0.9 12.3 11.8 6.2 2.0 2.8 6.8 5.6 3.4 3.4 5.4 6.5 7.2 4.8 6.8 13.6 3.7 7.3 11.0 1.7 5.4 8.4 4.8 0.1 3.3 4.9 1.9 2.6 4.2 6.0 5.2 3.4 3.9 14.1 1.7 4.1 1.9 1.6 13.7 3.5 0.0 5.6 6.9 2.0 0.0 4.3 2.2 4.9 0.9 8.0 3.8 10.0 0.0 5.2 6.2 9.1 6.0 5.2 1.1 1.7 26.6 9.0 2.8 5.6 5.3 6.0 16.8 3.2 2.1 3.2 4.5 5.2 4.8 10.1 5.3 19.1 12.7 3.6 5.2 5.9 0.6 6.2 1.8 7.7 2.8 5.8 2.8 1.2 1.0 0.2 0.3 0.0 1.2 0.6 0.2 0.3 0.3 0.2 0.0 6.5 0.7 0.4 0.2 0.5 0.2 2.9 2.9 3.5 3.8 2.8 3.1 3.7 3.1 3.2 2.8 3.4 3.7 12.6 12.8 18.1 7.8 17.5 18.0 18.1 10.3 6.8 10.4 11.7 8.4 8.7 15.7 12.7 12.9 16.7 4.8 24.3 25.6 5.9 8.1 4.3 24.9 11.1 12.1 13.8 10.8 13.5 8.2 4.7 12.1 19.9 27.9 1.3 5.4 12.8 8.1 9.1 16.8 13.3 13.0 4.1 27.9 15.2 2.0 7.2 21.1 7.2 9.4 13.7 7.3 14.4 7.5 20.8 18.3 17.7 7.9 22.9 27.2 8.6 10.5 11.9 8.2 0.0 17.7 7.6 7.6 3.7 10.0 16.3 8.6 18.5 9.3 12.2 43.1 PLK4 "Sak, STK18" ENSG00000142731 "Polo like kinase 4" O00444 4 127880893-127899224 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 22.6;lymphoid tissue: 14.4;testis: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 65.9;Late spermatids: 87.5;Spermatocytes: 53.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017327, HPA035026, HPA043198" Approved Supported Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Centrosome, Cytosol" "HPA017327: AB_2669584, HPA035026: AB_10602080, HPA043198: AB_2732504" "unprognostic (2.44e-1)" "unprognostic (4.24e-2)" "prognostic favorable (7.46e-5)" "unprognostic (2.18e-1)" "unprognostic (3.79e-1)" "unprognostic (9.20e-2)" "unprognostic (1.06e-5)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.44e-3)" "unprognostic (5.66e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (1.27e-1)" "unprognostic (2.22e-11)" "unprognostic (2.29e-2)" "unprognostic (3.58e-1)" "unprognostic (4.75e-2)" "unprognostic (7.93e-2)" 1.0 1.1 0.4 4.9 0.5 22.6 2.0 0.2 0.7 0.9 0.1 3.5 2.8 1.5 0.6 3.2 1.3 1.1 0.5 0.5 0.6 0.6 0.8 0.9 7.4 0.5 0.5 1.0 0.4 0.6 0.2 3.6 0.4 0.9 4.3 2.1 0.9 0.9 0.1 2.3 2.9 1.8 0.4 1.6 2.0 22.6 0.6 14.4 0.9 0.7 7.3 1.3 1.4 0.4 26.1 12.1 44.3 22.9 1.5 4.2 20.1 24.9 17.6 32.4 33.3 17.0 26.1 34.9 9.0 13.9 26.3 16.7 31.6 19.9 49.6 27.4 13.1 31.6 20.0 16.0 0.5 45.2 35.9 1.4 2.0 29.7 13.6 5.9 25.3 26.3 37.5 45.2 27.6 18.2 69.9 20.1 20.7 26.3 13.6 36.0 30.9 12.1 10.8 16.4 24.4 20.0 15.8 14.2 7.6 18.7 11.5 19.3 11.0 25.3 24.4 17.4 31.4 23.1 27.4 49.0 13.0 33.7 28.7 0.0 0.1 0.4 0.4 0.2 0.3 0.1 0.5 0.5 0.2 0.2 0.1 0.6 0.0 0.4 0.1 0.1 1.2 0.2 0.4 0.5 0.2 0.7 0.5 0.6 0.5 0.5 0.4 0.4 0.6 0.4 1.6 0.0 0.6 0.0 1.6 1.7 0.9 1.7 1.2 1.8 1.0 0.9 0.9 0.0 0.6 1.8 0.0 6.0 1.9 2.0 0.0 0.6 65.9 4.7 1.0 1.0 2.4 19.6 0.8 0.4 12.9 1.6 4.1 2.0 1.3 7.5 0.4 0.5 3.7 0.0 0.8 3.3 6.1 1.3 0.6 87.5 2.8 1.5 0.0 1.0 1.2 1.1 1.0 1.0 1.2 0.1 0.5 0.4 8.7 0.7 0.5 0.6 3.7 0.8 0.0 0.4 3.6 53.5 13.4 6.8 0.9 3.8 2.1 0.8 4.5 1.7 PLOD1 "LH1, LLH, PLOD" ENSG00000083444 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1" Q02809 1 11934205-11975538 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 236.8;Sertoli cells: 105.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049137, HPA055799" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles Nucleoplasm "HPA049137: AB_2680649, HPA055799: AB_2682924" "unprognostic (1.00e-1)" "unprognostic (2.69e-3)" "unprognostic (9.21e-3)" "unprognostic (5.43e-2)" "unprognostic (7.53e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.13e-3)" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (4.15e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.91e-12)" "unprognostic (2.79e-1)" "unprognostic (7.12e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.43e-4)" 58.1 34.6 46.3 35.2 51.2 16.1 41.2 48.6 56.6 65.4 46.4 47.3 37.7 65.0 30.5 21.3 51.1 42.0 71.2 44.5 47.4 45.5 78.1 44.4 15.4 49.6 50.8 54.4 39.0 36.9 29.6 83.8 52.4 34.7 23.2 10.6 75.9 40.6 40.5 27.2 35.6 78.4 44.8 31.5 35.5 11.6 52.2 7.9 34.9 41.6 12.9 42.4 36.0 53.1 112.5 91.4 51.3 239.7 343.4 190.6 39.0 330.4 436.1 170.4 287.1 105.2 71.5 63.1 339.5 367.3 125.9 93.4 75.6 115.6 115.6 66.2 78.3 34.0 136.6 137.3 212.5 21.9 162.7 234.0 59.7 206.2 81.9 573.3 305.0 14.8 97.6 30.9 180.2 71.1 5.7 58.6 22.9 115.4 131.6 25.8 100.0 141.0 98.7 24.3 19.2 77.7 137.3 97.4 164.8 80.4 48.3 55.9 298.7 190.1 141.6 236.3 161.9 71.4 123.7 38.7 425.1 75.5 316.8 0.0 40.3 2.0 17.3 34.4 3.1 1.7 3.0 8.4 32.7 3.4 1.2 6.4 35.5 5.4 32.3 4.9 2.0 22.6 46.3 51.2 48.6 56.6 44.5 47.4 49.6 50.8 52.4 44.8 52.2 53.1 19.4 0.0 7.9 9.4 3.7 7.0 8.0 22.8 8.0 5.7 17.9 17.5 18.3 8.6 8.6 11.0 2.1 39.7 8.7 14.8 3.9 30.3 1.0 11.0 62.2 33.9 8.4 3.0 4.2 9.8 236.8 47.5 17.3 24.8 0.0 20.4 36.8 37.1 46.3 6.7 5.8 12.5 4.1 26.5 8.3 2.4 44.4 16.3 10.6 15.9 17.9 7.9 15.5 3.0 9.8 22.4 15.4 24.5 19.4 8.0 41.5 16.7 4.5 3.1 105.2 77.2 47.3 0.5 3.3 7.4 5.1 33.7 5.5 37.1 16.6 3.9 PLOD2 LH2 ENSG00000152952 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2" O00469 3 146069440-146163653 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 130.9;Basal respiratory cells: 115.1;Distal enterocytes: 143.7;Extravillous trophoblasts: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBF TERT88: 636.0;hTERT-RPE1: 723.8;U-87 MG: 566.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025898, HPA069126" Approved Uncertain Nucleoli,Cytosol "Intracellular and membrane" NA NA 21000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "CAB025898: , HPA069126: " "unprognostic (8.68e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (2.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (1.29e-3)" "prognostic unfavorable (7.64e-10)" "prognostic unfavorable (1.42e-4)" "unprognostic (2.97e-2)" "unprognostic (3.36e-2)" "unprognostic (6.27e-3)" "unprognostic (2.24e-1)" "prognostic unfavorable (4.99e-11)" "prognostic unfavorable (2.83e-4)" "unprognostic (6.07e-2)" "unprognostic (4.06e-2)" "unprognostic (4.41e-3)" 63.1 20.1 13.4 35.6 14.5 1.1 18.6 15.1 17.2 10.2 19.4 36.2 42.2 23.5 13.4 18.2 11.4 41.5 22.1 13.3 15.1 26.1 57.3 12.9 3.8 23.1 18.1 20.5 18.7 16.5 7.9 80.6 16.3 13.2 29.9 56.6 9.5 16.2 3.0 3.9 35.0 46.8 17.8 5.4 20.1 8.5 20.6 10.5 90.0 3.9 5.5 25.7 10.0 17.6 134.5 94.3 29.0 9.5 102.5 109.6 73.2 465.5 141.6 247.7 463.0 7.2 13.4 0.0 88.8 79.5 113.1 27.8 34.0 400.5 636.0 0.6 53.5 33.3 84.3 66.9 262.5 0.1 0.6 192.9 56.5 215.2 104.1 723.8 347.7 0.1 45.1 1.8 441.6 48.8 0.3 0.6 18.5 0.3 40.0 0.2 19.2 0.6 105.0 6.5 14.5 0.5 370.3 39.4 39.9 135.1 107.5 4.2 440.4 304.2 92.2 97.8 280.7 138.9 20.9 0.5 566.5 0.4 55.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 13.4 14.5 15.1 17.2 13.3 15.1 23.1 18.1 16.3 17.8 20.6 17.6 29.1 16.0 11.4 130.9 0.4 7.0 6.4 115.1 30.1 17.1 23.7 10.2 14.3 44.3 47.0 27.6 35.5 9.2 0.3 143.7 9.8 64.5 0.5 35.4 13.8 24.3 19.8 4.6 22.8 53.1 130.6 68.1 19.9 38.7 0.0 42.7 21.0 65.2 5.1 0.0 46.4 19.5 22.4 1.0 2.5 1.2 13.1 3.0 14.2 21.5 0.7 53.8 0.0 64.3 6.0 82.4 48.8 4.9 1.3 8.9 50.5 8.2 33.0 24.7 19.7 36.9 47.2 11.0 18.0 27.5 5.5 18.7 1.0 24.5 25.1 5.6 PLOD3 LH3 ENSG00000106397 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3" O60568 7 101205977-101218420 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Dioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "melanoma: 115.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 20.3;monocytes: 22.5;T-cells: 12.6" "Cell line enhanced" "Detected in all" "Karpas-707: 695.6;WM-115: 680.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001236 Uncertain "Secreted to extracellular matrix" NA NA 1600000 "Cluster 39: Non-specific - mRNA processing" "Cluster 15: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA001236: AB_1855474" "unprognostic (1.15e-1)" "prognostic unfavorable (1.91e-5)" "prognostic unfavorable (3.26e-4)" "unprognostic (1.39e-1)" "unprognostic (2.76e-3)" "unprognostic (1.04e-2)" "unprognostic (6.26e-3)" "unprognostic (1.11e-3)" "unprognostic (8.00e-3)" "unprognostic (1.18e-2)" "unprognostic (4.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.21e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (8.52e-3)" "unprognostic (9.87e-2)" 41.9 27.3 43.6 22.9 53.2 19.6 32.8 54.9 58.5 33.3 46.8 37.8 25.7 38.9 11.7 12.2 32.5 18.8 42.6 43.6 46.3 36.3 54.1 37.5 14.6 61.1 52.3 26.3 41.8 21.5 27.1 35.0 58.9 24.2 15.3 3.9 19.4 18.6 15.3 19.1 35.9 26.0 49.4 35.3 30.0 12.9 51.7 8.0 25.3 11.8 7.5 35.2 25.2 71.9 71.7 62.4 27.1 168.2 116.2 83.9 51.4 125.5 135.9 122.7 88.6 98.0 89.0 5.6 140.2 211.4 100.7 83.0 50.0 72.0 31.2 37.8 23.8 7.2 70.7 97.3 157.6 31.5 57.4 90.8 67.6 71.6 55.4 120.2 110.9 4.6 68.4 695.6 84.2 194.5 3.4 72.1 53.5 120.5 94.9 21.8 35.1 108.3 42.0 19.1 21.2 116.0 81.1 116.2 288.1 66.8 21.9 105.2 100.5 188.1 94.9 228.1 155.0 38.5 75.9 5.2 112.4 74.2 680.2 0.0 18.1 4.4 12.6 21.8 10.9 3.7 9.3 8.3 16.5 2.2 4.1 4.5 1.8 3.6 22.5 20.3 6.7 9.5 43.6 53.2 54.9 58.5 43.6 46.3 61.1 52.3 58.9 49.4 51.7 71.9 34.1 22.4 8.7 11.1 9.7 8.9 10.8 18.9 8.0 5.7 8.1 9.1 16.1 21.5 8.7 25.8 14.6 20.4 22.0 37.6 1.9 40.2 0.6 10.8 29.9 28.5 16.2 19.1 11.9 31.6 71.6 34.2 17.9 20.5 19.7 25.9 26.7 18.3 50.1 8.4 10.8 18.0 4.1 23.3 18.3 2.1 26.1 23.2 62.2 4.7 18.9 7.7 12.3 10.1 33.4 36.1 37.8 14.7 19.7 8.0 45.8 8.8 9.3 7.3 19.7 14.3 29.8 8.9 12.4 1.9 4.8 18.9 12.5 18.4 27.3 5.2 PMVK "HUMPMKI, PMK, PMKA" ENSG00000163344 "Phosphomevalonate kinase" Q15126 1 154924740-154936719 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 266.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029900 Approved NA NA 15000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA029900: AB_10601390" "unprognostic (2.52e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.31e-1)" "unprognostic (1.81e-2)" "unprognostic (8.13e-2)" "unprognostic (5.47e-2)" "unprognostic (8.22e-2)" "prognostic favorable (9.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "prognostic favorable (4.96e-4)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.10e-1)" 39.9 56.4 99.0 29.8 100.1 15.3 35.0 97.9 108.9 33.4 95.0 39.9 45.9 25.9 17.7 77.7 37.2 17.2 63.1 93.9 96.4 53.8 91.9 30.1 34.6 98.6 97.4 35.8 41.6 58.2 60.3 23.7 96.0 32.4 22.2 19.8 34.0 27.1 79.1 69.2 44.2 27.7 96.4 45.7 40.5 26.6 102.3 27.9 31.5 47.4 36.8 31.9 37.9 99.8 51.8 72.9 46.7 72.5 43.6 30.9 48.5 40.5 29.3 38.9 37.0 30.6 101.0 75.1 75.9 49.3 40.5 49.4 65.3 63.9 17.8 103.3 28.9 34.1 104.1 29.0 40.0 51.4 29.3 36.3 58.7 70.2 49.6 19.5 40.0 65.9 36.8 221.7 41.3 108.3 40.8 51.0 41.0 121.7 95.0 60.3 29.8 171.1 66.1 38.4 37.7 91.1 44.1 75.7 51.9 35.0 146.7 91.1 32.7 35.8 29.2 84.4 62.1 174.0 153.2 131.8 58.9 83.9 46.7 28.0 80.9 91.8 68.2 205.6 110.1 114.8 93.1 70.6 93.6 111.1 59.1 59.1 6.9 59.7 219.4 96.5 134.3 80.0 99.0 100.1 97.9 108.9 93.9 96.4 98.6 97.4 96.0 96.4 102.3 99.8 22.7 57.7 37.5 9.4 42.2 69.8 105.9 95.8 51.8 38.5 67.1 68.3 57.3 78.6 42.2 53.3 8.4 235.7 31.5 65.0 266.1 69.6 9.0 45.0 28.5 29.8 66.4 35.6 5.1 71.3 108.1 45.1 46.9 44.2 22.2 49.8 39.3 146.9 141.0 37.0 7.0 78.9 67.1 67.9 49.5 13.5 42.6 47.8 65.8 3.7 49.5 119.1 41.2 8.0 11.8 61.7 61.7 47.8 58.8 53.7 219.3 246.1 22.1 27.4 32.9 46.0 48.4 51.3 51.3 81.0 90.5 227.7 45.1 162.6 79.9 76.2 PNPLA1 "dJ50J22.1, FLJ38755" ENSG00000180316 "Patatin like phospholipase domain containing 1" Q8N8W4 6 36243203-36313955 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 23.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.9;granulocytes: 4.5;Oligodendrocyte precursor cells: 1.5;Proximal enterocytes: 1.5;Proximal tubular cells: 3.8;Suprabasal keratinocytes: 3.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basophil: 69.8;eosinophil: 18.9" "Lineage enriched" "Detected in many" 17 "granulocytes: 69.8" "Cell line enriched" "Detected in some" 4 "U-937: 17.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.57e-2)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-4)" "unprognostic (1.69e-1)" "unprognostic (1.47e-1)" "unprognostic (7.37e-2)" "unprognostic (2.49e-1)" "unprognostic (8.89e-2)" "unprognostic (1.13e-2)" "unprognostic (2.95e-1)" "unprognostic (2.76e-2)" "unprognostic (2.70e-2)" "unprognostic (9.85e-2)" "unprognostic (2.06e-1)" "unprognostic (2.04e-2)" "unprognostic (1.65e-2)" 0.1 0.2 0.1 0.6 0.2 4.3 0.6 0.3 0.4 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 4.7 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.2 23.9 0.9 0.2 0.1 0.7 1.7 1.0 0.2 0.1 0.1 0.0 0.1 0.2 0.6 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 17.6 0.0 69.8 4.0 18.9 0.0 2.2 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.2 6.2 0.1 1.1 0.0 0.0 1.1 0.1 0.2 0.3 0.4 0.1 0.1 0.2 0.0 0.2 0.1 0.2 0.3 0.0 0.0 0.0 1.0 0.0 0.9 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.2 4.5 0.7 0.0 0.0 0.2 0.0 1.2 0.4 0.0 0.0 0.3 1.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 1.5 0.7 0.1 0.0 0.0 0.0 0.1 1.5 3.8 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 3.7 0.1 0.0 0.4 0.2 0.2 POC1A "DKFZP434C245, WDR51A" ENSG00000164087 "POC1 centriolar protein A" Q8NBT0 3 52075226-52154690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Dwarfism, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 12.8;testis: 17.6" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Extravillous trophoblasts: 33.8;Late spermatids: 73.4;Spermatocytes: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040600 Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA040600: AB_10672837" "unprognostic (2.68e-1)" "unprognostic (7.17e-2)" "prognostic favorable (1.78e-4)" "unprognostic (5.08e-2)" "unprognostic (3.61e-1)" "unprognostic (1.31e-1)" "unprognostic (1.02e-3)" "unprognostic (2.41e-2)" "unprognostic (7.23e-3)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (9.43e-7)" "unprognostic (9.90e-3)" "unprognostic (1.96e-1)" "unprognostic (3.62e-2)" "unprognostic (2.32e-2)" 1.4 4.1 1.5 4.0 1.5 11.1 2.2 1.4 1.8 1.5 1.1 5.9 4.8 1.0 1.0 4.7 1.7 1.1 1.4 1.7 1.6 2.1 5.2 1.9 5.4 1.9 1.6 0.7 0.9 1.1 0.7 4.1 1.8 1.3 6.0 0.4 1.3 1.0 1.5 2.6 4.0 2.9 1.5 2.8 2.8 17.6 1.6 12.8 1.0 1.0 7.0 2.0 1.8 1.8 30.1 25.2 25.0 33.5 5.1 6.5 33.9 30.0 28.7 62.8 48.7 22.1 31.0 31.3 8.8 23.9 48.6 18.3 38.0 33.9 45.3 26.0 16.0 21.4 26.3 23.9 1.4 24.5 13.0 3.6 7.3 49.6 25.9 8.7 29.0 46.2 18.8 32.9 37.5 23.8 45.6 44.2 19.1 33.7 41.0 19.6 19.7 30.0 14.2 21.0 11.6 16.7 24.0 23.7 18.3 26.0 29.2 45.7 9.7 28.6 27.6 46.3 49.3 27.8 49.1 26.6 19.2 42.6 29.1 0.0 1.6 0.0 1.2 2.2 0.1 0.9 0.8 0.4 1.9 0.5 0.7 0.4 0.5 1.4 1.6 1.9 2.6 1.1 1.5 1.5 1.4 1.8 1.7 1.6 1.9 1.6 1.8 1.5 1.6 1.8 0.9 0.0 1.3 0.3 2.5 1.7 1.6 4.7 0.0 0.7 2.1 2.2 0.7 0.0 1.4 1.8 0.0 21.8 0.9 4.4 0.0 1.8 47.9 4.5 1.0 2.9 1.8 15.6 2.3 3.0 33.8 3.4 2.0 1.5 0.0 11.3 1.8 4.2 12.9 1.7 1.4 5.4 0.0 2.6 3.4 73.4 1.2 2.6 1.8 1.9 2.7 0.8 1.0 0.0 2.7 2.1 2.2 0.4 12.9 1.3 3.0 3.2 4.2 0.0 0.0 1.1 3.4 40.1 21.2 4.9 1.8 7.5 1.6 4.4 8.4 2.1 POLE POLE1 ENSG00000177084 "DNA polymerase epsilon, catalytic subunit" Q07864 12 132623753-132687376 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 46.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebellum: 4.1;cerebral cortex: 1.1;hippocampal formation: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA058210, HPA067385" Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Plasma membrane" "HPA058210: AB_2683639, HPA067385: AB_2685830" "unprognostic (1.60e-1)" "unprognostic (1.77e-3)" "unprognostic (2.00e-1)" "unprognostic (9.17e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-2)" "unprognostic (3.96e-3)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (7.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.19e-8)" "unprognostic (8.60e-2)" "unprognostic (3.18e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" 6.0 2.9 0.2 6.1 0.2 24.7 6.0 4.1 1.1 6.4 0.3 7.3 6.5 5.4 2.1 7.0 6.2 3.1 4.3 1.6 0.0 3.0 8.6 5.0 7.2 0.3 0.1 7.8 6.5 2.6 2.7 5.3 0.3 6.4 6.3 2.4 6.1 3.3 7.5 13.2 8.5 3.7 0.1 16.2 8.0 16.2 0.5 15.7 4.7 3.0 7.1 6.1 6.2 0.3 25.3 33.3 48.7 22.0 10.2 7.6 39.9 26.0 11.7 30.3 21.8 38.3 14.5 28.7 10.2 14.1 11.6 33.6 35.4 16.7 18.8 13.3 41.2 45.4 45.7 15.2 1.9 37.2 24.9 5.5 6.0 31.8 10.5 8.1 10.8 35.1 53.4 15.7 14.9 33.3 61.8 46.8 36.9 9.3 18.5 48.0 27.6 13.0 6.9 40.8 40.6 22.0 30.0 22.7 4.7 23.4 35.0 19.1 9.9 26.5 24.7 20.6 25.9 20.3 14.5 44.8 14.7 26.3 19.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.2 4.1 1.1 1.6 0.0 0.3 0.1 0.3 0.1 0.5 0.3 3.2 0.0 6.7 7.5 4.0 5.7 3.8 3.0 4.0 8.7 7.8 6.7 6.9 1.5 1.6 1.8 0.0 8.8 5.6 18.8 0.0 2.3 8.2 3.2 3.8 4.9 7.2 14.9 13.6 3.3 10.8 5.1 11.2 6.8 2.5 16.2 8.9 10.5 13.2 0.0 7.6 9.1 2.0 6.9 5.4 9.7 6.8 2.9 5.4 4.7 1.6 2.6 2.1 3.5 2.9 2.6 6.0 3.4 6.3 4.0 4.1 1.0 1.9 6.1 26.3 7.0 6.1 46.6 18.2 5.8 7.7 4.0 5.8 2.9 10.9 2.8 POLH "RAD30A, XP-V" ENSG00000170734 "DNA polymerase eta" Q9Y253 6 43576185-43620523 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 25.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 91.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006721, HPA026762" Approved Enhanced Nucleoplasm NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA006721: AB_1847785, HPA026762: AB_10601248" "unprognostic (1.79e-1)" "unprognostic (7.29e-2)" "unprognostic (2.25e-1)" "unprognostic (7.28e-2)" "unprognostic (3.61e-1)" "unprognostic (5.11e-3)" "unprognostic (9.68e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (7.75e-2)" "unprognostic (4.11e-3)" "unprognostic (2.24e-1)" "unprognostic (9.50e-2)" "unprognostic (6.73e-2)" "unprognostic (8.77e-2)" "unprognostic (7.91e-2)" "unprognostic (6.02e-2)" 5.0 3.8 2.3 6.9 2.7 4.2 4.8 5.1 2.9 5.9 5.3 7.0 4.6 4.2 3.6 5.5 5.5 4.3 3.7 2.2 2.2 4.7 5.6 5.7 12.9 2.7 2.2 4.7 5.4 3.7 3.2 4.0 2.7 4.7 7.2 7.4 4.0 3.8 8.5 8.5 4.4 6.3 1.8 5.6 4.6 10.6 2.5 12.9 6.8 4.7 14.2 4.8 4.3 3.6 46.7 9.7 13.5 19.9 17.6 29.1 33.0 48.6 13.9 26.2 29.2 12.0 7.9 48.9 12.0 17.6 7.6 11.4 13.1 28.6 31.5 25.9 10.0 15.3 31.6 35.5 13.4 26.8 19.2 19.5 33.4 21.5 11.3 10.6 24.3 14.5 24.0 29.6 33.0 15.0 23.9 6.4 4.2 33.2 7.2 25.1 14.3 11.8 9.9 34.6 15.1 5.4 14.5 12.9 7.3 15.4 17.9 10.8 36.2 23.6 24.4 12.2 25.2 28.0 21.3 91.1 11.8 14.5 27.3 4.1 1.7 2.7 4.2 1.6 3.8 5.0 3.5 3.1 1.3 4.9 2.8 3.0 1.7 4.2 1.6 2.6 4.6 2.0 2.3 2.7 5.1 2.9 2.2 2.2 2.7 2.2 2.7 1.8 2.5 3.6 3.1 12.8 8.2 12.1 15.1 4.7 3.2 4.8 19.4 6.3 3.4 3.3 2.3 5.7 6.5 3.7 10.4 2.4 5.2 6.3 5.9 2.1 11.4 10.2 4.8 2.8 5.4 5.7 14.8 0.9 2.8 5.3 8.2 9.0 0.0 6.1 1.4 2.4 1.7 0.0 15.3 2.2 4.1 2.2 2.2 7.3 3.4 3.0 1.8 6.5 3.2 2.6 2.1 10.1 13.4 1.9 4.5 3.0 12.7 2.2 3.1 2.3 5.4 9.4 0.0 7.0 5.0 25.9 6.7 13.0 3.0 1.9 8.8 5.6 3.0 2.3 POLR1A "DKFZP586M0122, FLJ21915, RPA1, RPA190, RPO1-4" ENSG00000068654 "RNA polymerase I subunit A" O95602 2 86020216-86106155 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010145, HPA031513, HPA049700" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center,Intermediate filaments" No No "Cluster 7: Monocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoli fibrillar center" "Nucleoplasm, Intermediate filaments" "CAB010145: AB_675814, HPA031513: AB_2673916, HPA049700: AB_2680856" "unprognostic (1.22e-1)" "unprognostic (1.82e-2)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "unprognostic (1.32e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (3.70e-9)" "unprognostic (1.06e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.31e-2)" "unprognostic (4.56e-2)" "unprognostic (3.27e-1)" "unprognostic (2.20e-3)" "unprognostic (1.94e-1)" "prognostic unfavorable (8.41e-4)" "unprognostic (7.20e-2)" 5.4 5.7 3.7 5.8 4.0 4.9 4.5 3.1 4.7 4.9 4.0 4.9 4.1 8.2 3.0 6.0 5.2 2.9 5.8 3.9 3.6 4.6 5.0 4.0 4.6 3.4 3.6 5.2 5.2 7.1 4.9 5.0 3.3 4.5 5.0 3.5 3.9 5.1 10.8 5.5 3.8 6.9 2.7 3.8 4.5 6.2 4.4 6.2 4.5 7.4 4.9 5.2 4.2 4.3 18.5 41.1 18.0 34.7 17.2 13.7 25.9 16.6 10.9 23.2 14.4 51.9 14.2 41.9 17.2 17.0 22.7 20.9 46.6 24.4 20.6 17.6 24.0 36.2 18.0 35.1 12.1 34.8 18.7 10.5 15.0 34.6 26.7 8.8 18.2 19.0 48.8 10.3 16.2 16.4 25.8 15.1 32.7 24.4 26.8 30.7 39.5 19.6 10.5 29.7 27.7 14.6 18.3 23.8 12.7 12.3 14.0 12.0 29.3 28.0 22.2 24.3 33.8 14.5 15.3 35.7 14.6 29.3 25.3 0.5 0.4 0.0 0.7 0.6 0.9 0.5 0.3 0.6 0.4 0.6 0.3 0.4 0.1 0.5 0.5 0.7 0.1 0.4 3.7 4.0 3.1 4.7 3.9 3.6 3.4 3.6 3.3 2.7 4.4 4.3 4.9 3.2 9.1 13.4 8.8 4.2 4.9 5.3 12.0 12.4 6.2 5.5 11.1 8.6 4.7 9.2 16.7 6.3 7.2 5.1 3.9 6.0 3.0 5.4 13.8 6.5 9.6 10.9 19.7 4.9 5.4 7.7 8.2 6.9 6.3 11.0 4.2 8.3 12.5 11.8 18.1 6.7 2.0 3.1 3.5 1.7 6.2 5.5 5.4 6.5 3.3 4.2 6.2 20.1 18.2 6.6 3.0 5.3 10.1 9.1 3.5 3.4 5.2 9.7 0.0 14.3 6.2 5.0 7.2 13.4 2.7 3.8 7.5 12.4 10.4 4.0 POMP "C13orf12, HSPC014, UMP1" ENSG00000132963 "Proteasome maturation protein" Q9Y244 13 28659104-28678959 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026995 Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "HPA026995: AB_1845546" "unprognostic (2.00e-1)" "unprognostic (3.56e-2)" "unprognostic (2.26e-1)" "unprognostic (3.15e-1)" "unprognostic (8.58e-2)" "prognostic unfavorable (2.05e-5)" "unprognostic (2.71e-3)" "unprognostic (2.50e-2)" "unprognostic (9.90e-2)" "unprognostic (4.35e-2)" "unprognostic (4.83e-2)" "unprognostic (4.93e-1)" "unprognostic (1.39e-3)" "unprognostic (1.70e-2)" "unprognostic (9.41e-2)" "unprognostic (1.03e-2)" "unprognostic (9.81e-2)" 78.9 71.6 77.5 62.9 78.5 66.4 66.7 82.1 101.1 45.1 77.8 66.6 57.0 44.4 78.9 68.7 43.4 46.2 126.3 78.1 83.6 94.1 110.9 65.6 65.4 82.2 83.4 32.9 46.6 51.7 41.7 100.3 83.2 46.6 66.3 56.2 45.1 50.7 175.6 48.5 58.4 57.2 83.6 61.2 54.9 70.0 81.0 64.6 51.4 114.6 70.1 74.0 46.9 86.3 103.4 124.9 129.9 153.1 145.3 161.3 120.3 232.1 203.8 225.5 179.5 245.7 228.7 181.7 136.3 178.6 241.7 150.3 170.7 179.3 307.5 137.7 131.9 171.7 130.1 191.1 203.0 209.6 136.0 131.2 181.9 162.5 149.5 122.3 181.6 139.7 222.2 72.5 291.5 182.5 178.4 295.6 226.1 319.0 146.1 169.6 199.3 122.2 259.6 160.7 152.1 117.1 104.0 147.4 162.2 161.5 103.1 238.5 166.2 108.7 111.2 172.3 195.5 61.5 118.5 255.3 129.2 139.8 243.6 146.4 155.3 101.7 99.9 210.8 88.7 136.4 101.6 113.2 190.8 137.6 71.8 101.9 135.1 95.3 213.9 223.4 132.3 165.2 77.5 78.5 82.1 101.1 78.1 83.6 82.2 83.4 83.2 83.6 81.0 86.3 527.4 131.4 114.2 17.3 218.5 409.8 345.1 1106.2 124.1 110.1 194.3 229.9 806.2 204.5 523.9 239.1 54.2 660.4 255.5 410.0 600.7 566.3 1156.6 266.7 235.8 486.2 228.7 271.5 23.4 699.5 974.0 281.8 128.9 293.0 207.3 181.6 434.1 538.7 780.7 97.6 22.4 315.0 585.9 431.0 673.7 533.7 201.0 407.1 300.6 29.0 612.6 294.7 228.6 13.6 26.1 755.1 414.0 233.6 228.1 443.5 491.8 922.5 472.8 121.8 322.1 193.8 494.6 625.5 240.3 230.1 416.3 972.4 202.7 234.7 335.5 494.3 POR "CYPOR, FLJ26468" ENSG00000127948 "Cytochrome p450 oxidoreductase" P16435 7 75899200-75986855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Congenital adrenal hyperplasia, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 313.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 489.2;Proximal enterocytes: 274.2;Theca cells: 647.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 328.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004372, HPA010136" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 12000 "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" Cytosol "CAB004372: AB_627391, HPA010136: AB_1079657" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "unprognostic (2.81e-3)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (4.32e-2)" "unprognostic (1.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (9.89e-2)" 53.4 197.4 19.9 32.1 20.7 17.9 44.7 14.1 18.6 42.0 15.5 35.9 105.2 32.1 29.4 53.6 50.2 37.0 43.3 20.7 30.2 38.1 313.3 55.0 19.9 22.2 24.5 52.2 44.5 77.6 71.4 46.3 20.9 31.8 21.9 12.7 29.9 113.1 56.2 43.8 92.4 28.2 16.9 43.8 41.5 25.5 34.7 38.0 131.3 68.1 23.2 36.6 42.3 15.3 59.6 133.0 57.0 106.3 212.9 79.8 98.0 24.4 79.3 44.7 62.3 100.7 257.0 56.1 21.9 53.1 151.8 28.3 76.0 38.4 19.6 48.1 57.9 26.0 36.9 189.4 146.5 26.2 45.5 163.9 47.4 59.2 43.2 36.3 42.3 27.1 79.1 24.0 40.8 90.9 29.0 49.4 71.7 92.9 74.8 41.0 37.6 61.1 50.0 72.8 59.3 57.4 65.4 328.4 91.0 32.6 94.0 44.2 38.6 41.7 45.8 63.6 48.7 23.8 38.3 39.0 59.3 39.8 54.9 65.9 42.6 60.4 20.6 39.6 17.1 11.0 17.5 19.4 45.6 11.2 17.1 14.7 53.8 25.9 30.2 12.5 19.3 36.6 19.9 20.7 14.1 18.6 20.7 30.2 22.2 24.5 20.9 16.9 34.7 15.3 34.3 38.5 39.7 23.2 17.1 17.1 29.4 172.3 13.1 31.4 20.5 14.0 10.9 54.3 201.4 73.5 12.5 99.9 26.0 97.7 1.9 65.0 27.6 62.1 28.0 27.1 19.8 11.8 10.1 29.4 95.0 40.1 67.8 46.6 24.7 121.4 32.2 489.2 67.8 15.2 17.1 41.7 124.1 35.2 16.1 9.5 75.8 47.3 12.4 11.2 20.5 25.9 12.3 11.6 8.8 27.9 102.0 112.5 17.0 20.7 274.2 31.7 178.6 23.0 65.7 32.7 46.9 21.3 30.8 18.2 14.6 193.2 25.4 647.6 44.5 45.9 PORCN "DHOF, MG61, por, PORC, PPN" ENSG00000102312 "Porcupine O-acyltransferase" Q9H237 X 48508962-48520814 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 37.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 68.5;Club cells: 44.2;Pancreatic endocrine cells: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 176.9;LHCN-M2: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049215, HPA058413" Enhanced Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA049215: , HPA058413: AB_2683711" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (4.01e-2)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (1.26e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (2.09e-2)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (2.35e-1)" 5.2 37.3 8.7 3.3 8.3 2.9 4.7 7.0 10.6 9.1 4.5 6.3 2.3 7.1 2.1 10.8 5.8 4.6 11.5 11.2 7.0 3.7 1.5 4.6 3.6 7.1 6.6 4.3 3.5 9.8 4.7 2.4 7.2 4.5 1.6 7.4 4.9 11.6 7.6 5.9 3.7 4.6 6.2 4.5 5.2 5.1 7.7 2.3 6.3 3.5 3.3 6.2 7.1 7.8 13.1 15.6 3.8 26.6 15.9 9.4 1.6 3.7 7.7 5.8 3.9 1.8 19.7 1.1 15.9 8.3 6.5 17.3 5.5 176.9 1.8 8.3 1.8 2.2 9.0 3.8 23.4 2.0 22.5 12.2 20.6 16.8 36.0 13.5 5.3 6.4 1.0 12.1 60.8 3.7 2.0 2.8 4.9 4.0 10.4 4.0 4.6 20.5 9.8 5.1 4.2 6.5 30.8 5.9 5.9 2.5 6.7 1.0 3.3 15.0 7.8 36.4 6.8 10.4 6.3 1.5 43.0 4.9 8.7 16.9 5.5 6.8 10.8 4.9 8.5 3.2 7.1 9.0 6.8 3.5 4.7 7.1 1.1 8.4 4.3 3.6 4.9 4.7 8.7 8.3 7.0 10.6 11.2 7.0 7.1 6.6 7.2 6.2 7.7 7.8 5.4 6.4 2.8 5.2 3.8 4.0 5.3 68.5 8.0 15.4 2.9 4.6 3.4 4.3 44.2 16.5 18.8 0.3 7.3 0.8 1.9 6.9 0.2 13.4 3.5 5.7 6.0 1.3 7.8 9.9 1.3 5.0 3.6 17.8 5.7 3.9 5.0 0.7 3.5 8.4 7.6 2.9 12.2 2.7 4.5 0.1 5.6 2.5 3.6 2.8 3.1 10.1 10.3 6.0 2.8 36.4 1.8 4.1 6.3 2.5 0.2 0.7 8.7 15.5 6.6 4.0 4.8 2.9 4.9 4.2 3.8 8.2 6.9 7.5 1.5 6.6 PPIB "B, CYP-S1, CYPB, OI9, PPIase, SCYLP" ENSG00000166794 "Peptidylprolyl isomerase B" P23284 15 64155740-64163134 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Isomerase, Rotamase" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1473.7;Plasma cells: 2242.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011487, HPA012720" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" "Secreted to blood" No No 33000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" Nucleoplasm "CAB011487: AB_443295, HPA012720: AB_1847399" "unprognostic (3.00e-3)" "unprognostic (5.65e-3)" "unprognostic (2.81e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.65e-1)" "unprognostic (1.07e-3)" "unprognostic (3.69e-2)" "unprognostic (1.27e-2)" "unprognostic (7.19e-2)" "unprognostic (8.80e-3)" "unprognostic (2.87e-1)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.02e-11)" "unprognostic (7.05e-2)" "unprognostic (3.77e-2)" "unprognostic (1.82e-1)" "unprognostic (3.90e-2)" 375.5 377.5 230.7 449.5 240.3 571.9 361.9 247.9 259.2 611.5 257.2 401.0 365.0 383.9 899.0 298.8 401.5 379.2 262.0 229.7 256.9 312.3 737.4 351.1 344.5 258.1 241.4 386.2 644.2 345.4 416.8 515.2 255.1 375.7 411.3 72.3 513.1 488.6 62.2 205.5 334.3 482.4 247.0 360.5 375.0 110.0 254.9 315.6 672.8 91.1 346.4 510.9 295.6 262.6 675.6 847.9 736.7 1666.7 2577.0 1492.3 641.9 1570.3 2108.3 1248.7 1472.3 1242.6 1223.1 653.6 1227.4 2513.0 1235.3 1067.7 1384.6 1080.4 641.1 406.2 491.0 914.5 915.3 1643.7 2682.9 915.0 778.1 1374.2 1149.4 725.9 1751.3 1516.7 1539.2 301.1 645.9 2174.7 966.0 1102.6 280.6 1404.9 625.1 1879.0 529.5 520.6 784.1 3347.9 1312.7 1062.6 410.5 647.7 726.0 1224.5 1194.2 1086.0 727.6 2767.0 927.6 1213.7 975.8 679.2 1079.4 1152.5 1269.5 693.4 1129.0 1478.0 1238.2 716.7 712.5 491.7 929.6 547.3 931.8 827.8 645.0 762.4 930.9 541.4 411.3 558.0 347.5 668.1 369.3 2643.5 569.3 1512.3 230.7 240.3 247.9 259.2 229.7 256.9 258.1 241.4 255.1 247.0 254.9 262.6 389.3 125.0 209.0 16.6 375.3 160.2 426.2 614.6 234.5 34.5 264.3 303.8 0.8 270.2 328.7 272.2 31.3 625.9 560.0 271.0 90.1 665.1 19.0 295.8 910.1 285.0 297.0 172.6 10.2 566.4 1473.7 627.8 441.4 494.2 181.2 540.4 322.7 473.2 630.1 45.4 15.8 603.9 205.4 216.9 333.4 29.5 456.3 316.6 281.1 19.7 299.1 149.1 368.7 35.2 37.0 435.1 338.9 393.1 2242.6 569.3 338.6 287.4 168.2 43.7 230.1 204.3 445.6 38.4 76.6 337.0 144.8 1118.9 352.3 674.0 477.2 422.3 PPP1CB "MP, PP-1B, PP1B, PP1beta, PP1c, PPP1beta" ENSG00000213639 "Protein phosphatase 1 catalytic subunit beta" P62140 2 28751640-28802940 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 985.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022558, HPA065425, CAB069426" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3800000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022558: , CAB069426: , HPA065425: AB_2685489" "unprognostic (2.90e-1)" "unprognostic (5.03e-2)" "unprognostic (5.49e-2)" "unprognostic (2.00e-1)" "unprognostic (7.08e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.52e-6)" "unprognostic (3.47e-2)" "unprognostic (2.44e-1)" "unprognostic (3.15e-2)" "unprognostic (1.54e-3)" "unprognostic (3.95e-1)" "unprognostic (1.68e-1)" "unprognostic (3.66e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-1)" "unprognostic (2.26e-2)" 90.9 75.2 55.8 74.7 73.5 119.1 110.5 55.6 74.9 148.6 67.8 109.2 84.8 138.4 104.0 245.7 113.5 103.1 185.2 54.3 73.8 84.4 70.5 73.3 60.4 73.9 61.2 92.7 76.2 126.9 45.9 74.8 74.5 149.1 92.9 70.8 114.6 123.4 386.0 73.7 76.0 159.7 71.8 65.8 81.7 47.6 63.5 71.3 78.8 262.8 91.1 118.0 104.1 88.2 186.0 114.6 391.1 121.7 130.8 121.0 227.0 97.7 110.6 92.2 91.0 102.6 106.9 147.5 119.2 101.5 102.7 111.4 112.6 129.9 109.8 235.9 58.2 111.3 130.1 111.5 284.3 127.8 50.5 93.5 181.3 100.1 207.8 97.4 113.8 77.0 103.6 140.4 123.3 93.2 136.9 110.3 128.3 141.8 89.8 132.2 344.9 112.7 304.3 220.6 106.7 131.3 151.4 166.2 136.2 111.4 80.4 70.6 137.6 122.6 134.6 89.3 119.0 100.4 171.0 299.8 130.1 135.0 93.5 72.4 59.4 84.9 39.8 96.7 50.8 38.6 59.3 46.8 65.4 31.6 51.8 58.8 103.6 61.4 115.2 49.8 74.3 52.8 55.8 73.5 55.6 74.9 54.3 73.8 73.9 61.2 74.5 71.8 63.5 88.2 172.2 93.0 80.6 59.4 147.8 492.1 176.7 101.5 64.9 62.4 208.0 117.0 352.1 112.9 124.1 310.8 27.1 129.6 210.4 324.5 244.6 297.0 514.0 330.2 245.7 129.3 283.0 200.2 68.5 210.5 202.1 147.8 78.5 258.9 146.6 91.2 137.8 108.7 114.7 163.2 71.8 144.2 111.9 182.6 985.1 406.2 196.7 238.1 336.2 59.0 137.9 116.6 55.6 64.3 68.4 236.8 181.3 302.0 100.9 364.9 106.6 227.4 213.3 65.2 631.1 225.8 264.8 55.2 66.6 135.6 458.0 392.9 237.7 65.8 154.4 498.9 PPP1R15B FLJ14744 ENSG00000158615 "Protein phosphatase 1 regulatory subunit 15B" Q5SWA1 1 204403381-204411817 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" "Diabetes mellitus, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 125.7" "Cell type enhanced" "Detected in all" "Langerhans cells: 171.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061088 Approved "Golgi apparatus" No No "Cluster 18: Basophils - Vesicular transport" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA061088: AB_2684426" "unprognostic (2.91e-3)" "unprognostic (8.61e-3)" "unprognostic (1.90e-1)" "unprognostic (2.75e-3)" "unprognostic (1.25e-1)" "unprognostic (1.33e-1)" "unprognostic (5.31e-2)" "unprognostic (2.66e-2)" "unprognostic (7.37e-2)" "unprognostic (7.44e-2)" "unprognostic (1.60e-1)" "unprognostic (5.36e-2)" "prognostic unfavorable (8.74e-5)" "unprognostic (9.52e-3)" "unprognostic (2.47e-1)" "unprognostic (2.99e-2)" "unprognostic (7.50e-2)" 40.7 23.1 12.9 31.0 15.3 125.7 23.0 17.8 13.9 19.6 16.4 23.4 22.4 21.4 13.1 25.9 21.5 30.8 13.0 11.7 13.2 21.0 48.1 24.2 29.1 14.4 15.2 24.5 36.8 18.7 10.5 32.6 14.6 22.5 24.1 16.0 22.1 15.9 13.2 18.1 24.3 29.9 14.6 23.8 27.0 11.7 15.2 33.3 28.2 18.2 24.7 53.2 14.7 19.7 29.3 23.0 26.9 22.8 34.1 23.2 108.7 23.6 28.3 31.9 28.7 27.6 40.3 48.2 16.0 28.9 22.2 36.3 40.2 23.9 29.5 37.3 28.7 28.5 55.7 17.8 41.5 49.1 49.0 29.3 30.4 31.4 34.5 22.9 35.1 40.4 44.4 92.8 21.8 29.1 47.1 30.6 46.2 26.8 32.9 33.2 48.9 49.8 32.0 35.4 25.7 39.3 42.6 59.8 49.3 36.0 39.4 50.2 19.8 22.2 31.3 28.6 40.3 62.5 30.0 47.3 20.0 33.1 23.4 13.1 5.5 5.7 3.2 5.1 3.4 2.0 3.2 3.0 5.0 2.1 4.9 3.5 11.8 3.2 6.2 2.0 4.4 2.9 12.9 15.3 17.8 13.9 11.7 13.2 14.4 15.2 14.6 14.6 15.2 19.7 72.2 48.1 37.9 15.3 40.8 73.7 43.0 23.1 48.3 18.5 43.7 24.6 15.6 32.9 25.9 18.4 20.9 22.9 40.3 70.4 3.9 15.9 9.0 72.0 90.8 50.9 44.7 27.3 12.3 24.0 42.7 54.7 76.5 146.7 49.4 31.0 28.9 48.6 31.8 8.4 13.0 43.3 22.4 42.0 171.9 4.6 13.1 97.9 49.8 10.3 36.8 14.4 11.3 18.1 23.2 30.3 40.5 12.8 50.9 55.0 39.5 11.0 43.0 18.5 6.6 72.7 48.6 17.2 13.2 39.8 64.2 49.3 46.8 31.2 35.6 104.5 PPP2CA "PP2AC, PP2Calpha" ENSG00000113575 "Protein phosphatase 2 catalytic subunit alpha" P67775 5 134194332-134226073 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Meiosis "Hydrolase, Protein phosphatase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003848, HPA043236" Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "CAB003848: AB_562203, HPA043236: AB_2678379" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.60e-2)" "unprognostic (3.35e-3)" "unprognostic (1.26e-1)" "unprognostic (3.21e-2)" "prognostic unfavorable (7.33e-5)" "unprognostic (1.59e-3)" "unprognostic (1.57e-1)" "unprognostic (2.02e-1)" "unprognostic (1.34e-2)" "unprognostic (1.31e-1)" "unprognostic (5.24e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" 47.9 53.1 52.1 42.9 55.1 124.8 46.6 60.6 66.3 38.9 44.9 51.4 46.1 46.6 36.1 71.5 39.0 44.6 90.1 57.8 53.5 57.3 62.1 39.4 58.6 48.6 51.4 30.0 44.3 87.1 26.1 52.2 53.7 37.8 47.1 58.6 36.5 40.4 75.3 54.1 44.5 57.8 54.7 40.0 41.3 34.7 53.6 92.4 48.1 73.1 76.7 75.4 41.0 59.5 157.0 128.8 180.8 97.9 92.1 98.2 126.2 144.1 123.3 214.8 215.4 249.1 119.6 136.5 131.7 134.4 242.9 79.7 175.6 208.6 250.2 123.9 100.1 96.9 142.4 156.5 136.3 97.1 84.2 91.7 141.5 169.0 166.6 107.0 153.5 135.1 97.2 99.1 165.1 112.5 154.9 95.0 98.9 123.6 77.3 136.5 179.6 132.6 130.0 173.4 142.9 99.6 148.9 55.1 166.9 179.7 112.2 112.3 109.2 123.3 69.1 99.6 206.5 88.5 171.6 217.0 83.2 125.9 130.3 43.0 64.7 75.6 46.8 63.1 59.2 53.1 53.2 62.5 77.3 54.7 60.6 57.2 71.3 75.5 67.0 41.5 72.4 95.8 52.1 55.1 60.6 66.3 57.8 53.5 48.6 51.4 53.7 54.7 53.6 59.5 58.7 51.3 47.6 27.1 103.3 239.0 187.4 90.1 121.8 43.9 93.6 53.0 111.2 55.8 63.1 57.0 22.9 152.1 89.0 68.7 107.6 109.7 34.6 85.8 83.2 81.1 87.1 89.0 36.6 87.6 171.3 78.0 77.5 106.1 62.2 44.6 51.8 65.9 111.4 50.5 35.7 62.0 69.2 88.2 194.6 29.8 38.5 95.8 104.9 24.4 115.6 62.9 51.5 36.7 48.9 101.7 56.6 45.5 120.9 143.3 64.9 114.8 53.0 31.4 19.7 76.8 97.6 91.4 85.8 112.4 234.4 309.8 110.6 53.3 69.7 176.7 PQBP1 "MRX2, MRX55, MRXS3, MRXS8, RENS1, SHS" ENSG00000102103 "Polyglutamine binding protein 1" O60828 X 48890197-48903143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001880 Supported Enhanced "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" "HPA001880: AB_1079671" "unprognostic (7.25e-2)" "prognostic favorable (1.48e-4)" "unprognostic (5.98e-2)" "unprognostic (2.09e-2)" "unprognostic (2.73e-2)" "unprognostic (1.52e-1)" "unprognostic (1.78e-2)" "unprognostic (1.09e-2)" "unprognostic (1.10e-1)" "unprognostic (7.48e-2)" "unprognostic (4.33e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.68e-7)" "unprognostic (2.68e-1)" "unprognostic (2.52e-3)" "unprognostic (3.97e-2)" "unprognostic (5.70e-3)" 38.8 50.6 35.5 25.6 36.9 46.0 39.3 38.1 44.2 47.9 31.1 50.0 39.2 42.5 22.7 48.6 41.0 24.2 43.0 36.7 40.2 41.7 61.0 35.6 31.1 38.8 37.3 58.4 62.8 28.1 50.5 18.2 38.6 42.2 20.4 21.5 43.2 28.3 65.0 52.0 42.2 25.3 38.4 45.2 52.1 13.8 39.0 38.6 38.6 32.3 29.0 39.2 43.2 40.0 100.6 124.3 64.5 63.2 58.2 40.8 48.8 57.3 67.1 116.8 70.7 146.3 45.0 91.8 46.2 40.0 88.1 79.9 110.6 42.6 43.5 80.8 95.2 78.1 94.6 109.5 55.9 95.5 69.8 50.7 81.4 96.8 95.5 46.5 67.0 35.9 75.7 169.0 50.1 167.5 41.5 94.3 60.3 69.3 139.6 66.7 63.0 209.4 75.5 66.2 95.7 49.4 75.3 82.6 66.5 48.0 103.5 68.9 58.6 51.1 92.2 65.6 77.4 99.9 106.5 69.5 29.0 88.0 53.8 41.8 81.9 53.1 56.4 79.1 74.7 83.9 78.2 56.2 96.9 70.4 81.5 74.9 23.4 76.1 73.0 86.9 114.3 84.5 35.5 36.9 38.1 44.2 36.7 40.2 38.8 37.3 38.6 38.4 39.0 40.0 37.0 41.7 65.9 6.2 65.4 111.8 86.1 99.5 85.4 36.7 76.9 97.2 39.0 54.3 68.6 31.3 12.5 58.5 53.4 85.1 49.0 59.9 6.2 37.5 38.6 54.5 70.1 38.7 4.4 95.8 56.1 53.9 39.8 54.3 70.5 36.6 43.5 45.0 70.2 18.5 3.9 68.2 77.3 72.2 113.5 4.9 69.9 56.2 88.9 3.7 96.6 47.4 55.6 3.5 4.8 73.7 123.6 43.6 105.9 54.2 151.1 108.5 51.6 27.7 39.5 64.4 69.8 2.7 17.7 69.5 117.3 54.6 62.9 67.0 67.9 69.3 PRDM5 PFM2 ENSG00000138738 "PR/SET domain 5" Q9NQX1 4 120684919-120922870 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 51.2;Early spermatids: 75.6;Inhibitory neurons: 31.9;Late spermatids: 31.0;Oligodendrocyte precursor cells: 52.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "eosinophil: 7.5;neutrophil: 5.4" "Lineage enriched" "Detected in single" 32 "granulocytes: 7.5" "Cell line enhanced" "Detected in many" "U-266/84: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051406 Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear bodies" Nucleoli "HPA051406: AB_2681472" "unprognostic (7.74e-2)" "unprognostic (8.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.09e-1)" "unprognostic (7.20e-2)" "unprognostic (9.30e-2)" "unprognostic (3.28e-2)" "unprognostic (4.52e-2)" "unprognostic (5.09e-2)" "unprognostic (8.71e-2)" "unprognostic (6.29e-2)" "unprognostic (4.13e-1)" "unprognostic (3.00e-2)" "unprognostic (4.91e-4)" "unprognostic (2.34e-1)" "unprognostic (1.29e-1)" "unprognostic (5.56e-3)" 3.0 4.0 1.8 1.6 2.0 3.5 3.0 3.2 2.0 5.2 4.2 3.2 1.3 6.0 2.8 2.2 4.6 2.4 3.0 1.6 3.2 1.9 0.4 4.2 0.9 4.1 4.0 10.3 4.8 8.6 3.9 3.5 4.0 4.1 2.9 4.7 1.8 4.3 1.6 1.5 1.8 4.4 4.7 2.4 2.1 3.6 2.9 1.4 5.8 3.0 0.8 2.9 3.3 4.4 2.2 3.4 7.8 0.1 4.5 9.3 9.2 4.7 9.9 4.7 4.2 4.4 1.2 0.4 1.2 6.2 4.5 0.1 0.0 1.0 6.0 0.0 1.4 2.9 3.1 0.3 4.9 10.0 0.1 6.6 2.9 3.3 4.1 4.3 3.4 1.2 0.0 14.2 5.7 0.4 1.5 0.1 5.7 0.8 2.7 0.0 9.3 6.1 1.6 0.0 1.4 6.2 0.0 0.1 0.9 4.0 6.4 4.1 1.4 0.2 2.7 4.8 4.6 13.0 19.7 0.1 3.6 0.1 3.6 0.1 0.0 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.4 0.0 0.0 0.0 0.0 0.0 1.8 2.0 3.2 2.0 1.6 3.2 4.1 4.0 4.0 4.7 2.9 4.4 7.1 12.8 5.6 51.2 0.5 1.7 2.7 2.4 9.1 9.1 1.1 2.4 8.2 2.8 3.8 1.8 8.4 1.0 0.2 1.5 1.9 2.3 75.6 1.4 9.4 6.3 3.6 0.0 25.0 2.5 2.6 9.6 2.6 1.4 2.5 15.5 3.6 0.0 0.8 0.0 31.9 3.6 4.1 0.3 0.7 31.0 8.7 0.6 1.8 23.4 0.2 7.6 0.0 52.8 8.0 1.5 0.8 9.4 0.7 2.6 0.1 0.2 1.8 7.5 6.6 10.1 6.6 8.2 3.5 4.6 1.7 0.5 1.2 14.9 3.0 0.7 PRDM6 "KMT8C, PRISM" ENSG00000061455 "PR/SET domain 6" Q9NQX0 5 123089241-123194266 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.9;urinary bladder: 9.0" "Cell type enhanced" "Detected in some" "Astrocytes: 15.0;Endometrial stromal cells: 6.5;Excitatory neurons: 7.9;Fibroblasts: 10.7;Late spermatids: 7.1;Oligodendrocytes: 11.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.6;HEK 293: 5.2;HEL: 1.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.3" HPA030324 Uncertain Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 28: BEWO - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA030324: AB_10670032" "unprognostic (2.33e-1)" "unprognostic (1.39e-1)" "unprognostic (2.18e-1)" "unprognostic (2.32e-3)" "unprognostic (3.12e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.54e-2)" "unprognostic (4.66e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-7)" "unprognostic (9.30e-4)" "unprognostic (1.10e-1)" "unprognostic (3.43e-4)" "unprognostic (1.27e-1)" 0.7 0.1 0.2 0.3 0.2 0.0 0.6 0.2 0.3 0.9 0.6 4.9 0.2 0.7 0.1 0.6 0.4 3.3 0.5 0.1 0.2 0.3 0.1 2.9 0.0 0.3 0.4 1.9 0.3 0.1 0.3 4.2 0.4 1.3 1.0 0.2 0.1 0.1 0.1 0.2 0.6 0.7 0.3 0.0 0.6 0.3 0.2 0.0 0.8 0.2 0.2 9.0 0.6 0.3 0.0 0.0 0.0 0.3 0.3 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.1 5.2 1.1 0.5 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.2 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.1 0.2 0.3 0.4 0.4 0.3 0.2 0.3 0.5 0.0 0.0 15.0 0.0 1.9 0.1 0.0 0.0 1.0 0.6 0.3 1.4 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.1 3.3 0.6 6.5 0.5 0.0 0.0 7.9 0.2 0.3 10.7 0.0 0.5 0.0 2.4 0.0 0.5 0.8 0.0 6.4 0.1 0.0 0.8 3.5 7.1 2.1 0.4 3.6 4.7 0.8 0.2 0.0 3.0 11.0 0.1 0.0 1.2 0.1 0.2 0.0 0.8 0.2 1.0 0.0 0.7 2.2 2.3 4.4 0.2 1.3 0.4 0.4 6.1 0.0 0.1 PRG4 "bG174L6.2, CACP, FLJ32635, HAPO, JCAP, MSF, SZP" ENSG00000116690 "Proteoglycan 4" Q92954 1 186296279-186314567 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 93.2;liver: 185.7" "Group enriched" "Detected in some" 15 "Fibroblasts: 320.6;Hepatocytes: 364.7" "Cancer enriched" "Detected in many" 10 "liver cancer: 28.4" "Region enriched" "Detected in single" 33 "hypothalamus: 30.8" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.2" "Lineage enriched" "Detected in single" 12 "T-cells: 1.2" "Cell line enriched" "Detected in some" 6 "ASC diff: 284.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" CAB054258 Supported "Secreted to extracellular matrix" NA NA 4300000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB054258: " "unprognostic (8.67e-2)" "unprognostic (2.28e-1)" "unprognostic (1.82e-3)" "unprognostic (1.98e-1)" "unprognostic (1.77e-1)" "unprognostic (7.87e-2)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (1.28e-1)" "unprognostic (1.53e-1)" "unprognostic (5.03e-2)" "unprognostic (4.11e-1)" "unprognostic (1.91e-13)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (1.60e-3)" "unprognostic (7.05e-3)" 93.2 2.3 0.0 2.3 0.0 0.3 15.1 0.4 0.9 0.6 3.9 1.2 0.0 0.6 0.9 0.3 20.0 0.4 31.7 0.0 30.8 0.2 185.7 26.4 0.4 0.0 0.0 2.1 1.5 0.0 2.1 0.0 0.1 0.6 0.1 0.1 3.9 0.1 9.5 7.7 0.4 0.3 0.2 0.7 1.4 0.2 0.2 0.3 1.7 8.1 0.3 2.6 0.5 0.0 0.0 0.1 0.0 0.0 284.6 11.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 1.1 0.1 0.2 0.2 0.0 26.2 0.0 44.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.7 1.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.9 0.0 30.8 0.0 0.0 0.1 0.2 0.2 0.0 5.1 22.4 16.2 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 2.7 10.0 21.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.2 3.7 4.1 0.0 2.7 0.0 0.0 0.0 320.6 0.0 0.8 16.4 0.0 6.4 364.7 0.1 0.0 0.1 0.0 0.0 9.4 1.9 0.8 0.0 2.8 1.8 0.0 0.1 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.1 0.1 0.0 0.0 10.9 0.0 0.0 3.5 1.5 0.0 0.3 0.0 1.1 0.0 2.3 0.1 0.0 0.1 PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 310.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 116.8;Theca cells: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010361, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA 170000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "Cytokinetic bridge" "CAB010361: AB_2268772, HPA071185: AB_2686356" "unprognostic (1.08e-1)" "prognostic favorable (6.28e-6)" "unprognostic (2.09e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (1.38e-2)" "unprognostic (2.95e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (7.01e-2)" "unprognostic (3.41e-1)" "prognostic favorable (6.47e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.66e-2)" "unprognostic (6.14e-3)" 62.7 126.5 46.6 27.6 47.6 18.9 53.9 39.9 64.2 53.2 29.5 59.0 20.9 56.9 28.5 41.8 53.7 14.2 204.8 49.2 53.3 35.4 78.4 46.1 15.9 56.8 54.5 94.1 34.0 21.6 71.2 17.3 55.3 41.2 13.0 25.2 42.3 20.8 310.9 42.3 36.3 21.8 40.7 71.6 40.2 57.2 50.3 18.2 39.6 122.1 13.4 50.6 44.2 46.6 37.5 16.3 40.3 74.4 36.2 30.8 9.9 30.5 23.6 32.7 27.5 21.6 15.0 13.8 26.2 49.2 22.9 25.4 26.7 26.6 32.3 23.1 17.7 27.7 20.6 24.4 36.8 21.9 33.5 33.8 18.1 30.0 11.1 26.6 29.7 19.0 29.1 47.3 36.7 48.1 46.3 31.9 21.5 38.7 45.0 38.0 47.8 36.7 41.7 13.5 36.5 24.2 34.2 31.3 23.8 18.1 37.2 26.5 37.7 71.7 20.3 100.7 39.6 31.9 24.9 23.6 49.6 28.0 32.7 0.1 1.5 0.2 0.8 2.7 0.3 0.8 0.3 0.5 1.1 0.5 0.5 0.7 3.2 0.4 2.5 0.6 0.3 0.6 46.6 47.6 39.9 64.2 49.2 53.3 56.8 54.5 55.3 40.7 50.3 46.6 39.5 6.4 3.4 9.4 7.0 8.8 6.8 6.4 2.2 42.2 19.2 19.0 116.8 22.8 4.7 14.7 27.1 6.9 9.0 24.6 7.9 12.4 32.4 11.7 22.9 26.7 17.5 2.5 16.9 19.1 5.7 22.6 8.6 12.9 0.0 15.9 26.4 39.7 34.5 3.3 21.6 11.8 2.0 49.4 50.8 15.7 49.0 37.1 14.2 9.4 37.8 26.1 9.2 10.1 10.7 15.6 11.6 51.9 3.3 6.4 20.7 11.8 7.0 23.9 19.7 23.3 23.5 26.4 6.9 10.1 11.2 8.1 10.0 100.6 14.4 6.6 PRKACB PKACb ENSG00000142875 "Protein kinase cAMP-activated catalytic subunit beta" P22694 1 84078062-84238498 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 334.4;Inhibitory neurons: 348.8;Oligodendrocyte precursor cells: 302.6;Oligodendrocytes: 499.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010363, HPA029754, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA 130000 "Cluster 48: NK-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Cytokinetic bridge" "CAB010363: AB_2170182, HPA029754: AB_10601491, HPA071185: AB_2686356" "unprognostic (9.38e-2)" "unprognostic (1.18e-1)" "unprognostic (6.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.49e-4)" "unprognostic (1.28e-1)" "unprognostic (3.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "prognostic favorable (1.89e-6)" "unprognostic (1.22e-1)" "unprognostic (3.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.48e-1)" 16.5 47.7 79.4 26.1 101.6 16.0 17.7 70.0 113.3 19.8 0.0 55.9 10.8 19.2 38.8 17.8 10.0 26.2 23.8 100.7 107.5 23.8 20.8 15.8 41.8 53.5 44.4 17.8 27.8 23.5 24.7 11.5 65.4 30.6 51.7 71.6 83.7 27.3 4.9 4.1 12.7 28.8 59.9 36.0 34.1 8.1 91.0 63.5 25.2 13.5 36.8 27.6 7.7 110.0 8.6 16.9 26.4 31.8 29.9 26.1 12.3 41.7 31.4 20.8 19.4 0.4 7.5 45.1 28.0 32.8 38.0 5.8 12.6 13.6 22.0 44.1 6.8 99.3 21.3 3.2 29.4 39.8 2.2 15.6 6.0 20.2 11.2 30.2 97.2 16.7 3.2 25.2 34.3 1.6 51.8 21.0 26.1 0.1 11.8 39.6 41.2 27.3 50.5 30.2 8.6 33.4 23.0 8.8 25.6 19.7 8.1 8.2 86.8 28.7 22.4 29.4 31.9 18.6 24.2 45.3 13.7 41.5 36.5 56.3 7.5 16.4 59.3 10.2 47.7 35.2 43.4 52.9 19.4 28.4 65.0 69.5 3.8 73.1 16.2 11.1 44.2 66.8 79.4 101.6 70.0 113.3 100.7 107.5 53.5 44.4 65.4 59.9 91.0 110.0 9.5 0.0 1.5 118.8 56.6 5.1 7.2 3.5 11.4 44.9 11.5 9.1 44.4 21.5 5.2 14.7 35.5 1.9 103.0 115.5 33.2 6.2 2.9 11.4 27.0 13.4 21.7 52.3 334.4 11.9 1.2 17.0 16.3 14.0 58.9 15.2 28.5 17.0 27.1 47.1 348.8 58.1 4.1 62.3 24.4 3.6 14.9 51.6 16.0 95.5 14.6 35.6 96.8 302.6 499.0 20.6 42.2 21.8 53.9 10.0 4.5 25.6 6.3 34.4 13.1 14.1 20.3 13.9 8.0 8.1 2.8 0.7 87.6 11.4 51.1 9.1 PRKAR1A "CNC1, PRKAR1, TSE1" ENSG00000108946 "Protein kinase cAMP-dependent type I regulatory subunit alpha" P10644 17 68511780-68551319 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 606.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019378, HPA049979" Approved Approved Cytosol NA NA 1800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "CAB019378: , HPA049979: AB_2680980" "unprognostic (8.69e-2)" "unprognostic (6.97e-2)" "unprognostic (5.34e-2)" "unprognostic (2.04e-1)" "unprognostic (1.68e-1)" "unprognostic (4.39e-2)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (2.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (5.55e-2)" "unprognostic (8.56e-3)" "unprognostic (6.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" 125.9 158.2 72.0 124.1 83.2 57.1 118.4 76.7 119.1 151.2 97.3 70.0 51.7 145.5 122.3 98.5 141.3 125.2 430.0 89.0 102.1 164.3 150.8 163.7 111.4 85.6 91.8 202.8 63.1 300.2 88.0 164.3 105.0 114.5 79.1 132.2 169.7 137.6 250.6 63.8 58.7 132.1 71.7 121.7 86.9 130.8 91.8 109.4 173.6 147.4 103.6 136.4 67.6 93.5 95.5 180.0 225.9 136.1 294.6 331.7 33.9 125.7 257.9 192.2 168.6 70.5 125.5 96.3 84.3 276.7 196.8 77.2 168.8 204.2 273.8 65.8 60.4 149.1 154.0 233.0 213.0 115.8 160.2 239.1 207.4 222.3 185.9 215.0 324.6 80.8 68.5 147.2 236.4 181.0 128.2 60.9 83.9 97.7 121.4 88.1 373.6 106.7 292.4 204.3 81.8 110.3 115.4 207.6 496.8 208.5 162.8 161.1 232.2 269.4 127.6 123.3 119.0 121.6 93.5 142.4 163.0 107.8 171.8 149.6 108.3 189.4 48.6 101.0 48.8 42.8 35.9 43.6 105.9 32.3 32.1 35.9 208.2 76.1 120.9 34.7 50.9 113.5 72.0 83.2 76.7 119.1 89.0 102.1 85.6 91.8 105.0 71.7 91.8 93.5 134.1 147.4 263.4 38.5 126.0 142.8 100.1 136.8 116.7 99.6 106.8 65.4 606.2 81.5 156.4 252.0 66.7 77.4 127.4 58.1 178.1 80.7 407.9 142.9 116.4 131.8 136.9 52.5 76.1 52.0 86.8 163.2 78.5 110.3 185.0 78.2 158.1 120.7 146.1 139.7 78.4 53.3 136.3 176.2 171.1 93.7 133.6 151.1 192.1 46.9 142.3 125.1 78.2 57.3 76.3 74.6 51.5 190.7 95.6 85.3 27.1 210.1 307.7 59.9 85.5 123.2 210.9 219.8 54.2 122.4 131.7 82.5 117.3 184.0 43.9 112.8 PRKCSH "G19P1, GIIB, PCLD, PLD1, VASAP-60" ENSG00000130175 "Protein kinase C substrate 80K-H" P14314 19 11435284-11450968 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004465, HPA041940, HPA043560" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 55000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 50: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum" "CAB004465: AB_626622, HPA041940: AB_2677758, HPA043560: AB_2678553" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (2.45e-2)" "unprognostic (2.14e-1)" "unprognostic (5.65e-2)" "unprognostic (2.63e-2)" "unprognostic (2.52e-2)" "unprognostic (5.52e-2)" "unprognostic (1.16e-1)" "unprognostic (2.07e-3)" "unprognostic (1.28e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (7.69e-4)" "unprognostic (1.63e-3)" "unprognostic (2.10e-1)" "unprognostic (3.44e-1)" "unprognostic (1.18e-1)" 115.3 107.6 76.4 81.2 86.7 169.6 117.6 85.1 97.6 144.0 91.4 119.7 120.0 123.0 113.0 106.5 126.2 92.0 90.4 76.4 82.0 108.8 159.9 105.5 93.3 89.9 83.9 196.9 186.2 116.3 118.3 108.8 85.9 108.5 98.9 46.6 145.9 97.8 74.8 129.3 121.7 78.5 79.6 111.2 124.9 88.5 83.3 83.9 135.5 44.9 86.2 109.9 122.6 88.8 274.8 216.7 211.6 391.5 351.2 426.4 241.5 305.5 387.6 331.5 302.7 328.3 327.5 204.4 478.1 409.2 165.4 283.4 226.3 309.6 292.1 193.3 173.5 178.0 269.4 268.8 258.0 263.0 236.4 404.5 228.6 312.5 261.4 425.6 232.8 210.1 204.8 422.4 289.0 470.1 187.9 322.1 485.0 129.7 283.3 201.8 215.3 505.6 223.2 260.1 146.9 291.5 282.3 280.4 280.5 200.8 292.5 296.7 263.6 437.1 198.2 416.0 361.0 471.9 575.3 132.3 330.1 276.8 306.5 38.8 47.2 45.1 37.9 36.2 42.6 35.9 31.8 36.4 36.1 38.7 30.2 33.1 56.3 32.8 41.2 75.7 37.5 39.5 76.4 86.7 85.1 97.6 76.4 82.0 89.9 83.9 85.9 79.6 83.3 88.8 45.2 12.8 16.9 15.3 65.1 41.8 72.2 90.0 39.9 18.2 56.9 47.5 10.5 71.4 44.9 64.4 33.3 174.9 54.6 152.0 33.2 88.7 18.1 47.4 65.0 52.0 58.8 40.6 12.3 127.5 189.1 62.6 70.3 67.2 41.9 104.5 60.3 86.4 93.4 10.1 12.5 123.2 65.1 80.0 43.4 55.9 78.6 59.3 53.4 14.0 81.4 59.8 61.8 6.0 39.0 89.0 132.8 72.6 91.4 45.9 187.8 62.7 32.7 30.2 39.5 39.8 52.0 36.8 55.2 49.5 37.8 143.5 55.5 84.2 128.2 66.6 PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 362.1;Excitatory neurons: 147.4;Inhibitory neurons: 171.1;Microglial cells: 89.0;Oligodendrocyte precursor cells: 390.6" "Cancer enhanced" "Detected in all" "prostate cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 21.6;fHDF/TERT166: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favorable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.89e-1)" 8.0 9.6 5.6 2.2 8.0 0.0 7.7 6.5 6.7 6.4 3.7 9.5 1.0 7.9 3.5 2.1 6.5 4.4 6.1 7.5 7.5 17.5 1.6 7.5 0.3 8.6 8.6 11.2 5.4 10.6 5.6 1.9 8.7 14.7 1.3 4.7 2.9 9.3 1.6 2.8 3.6 6.3 8.9 2.3 4.6 11.7 8.1 2.4 5.9 2.6 0.5 13.1 4.6 10.3 0.0 4.4 4.8 3.1 21.6 16.5 0.1 14.1 10.4 16.7 7.3 0.0 0.3 0.0 1.9 19.4 4.0 0.1 7.9 2.1 6.8 0.0 6.2 0.0 0.0 0.5 8.8 0.0 0.1 18.4 0.3 1.4 1.5 6.1 2.6 0.0 1.4 0.4 17.4 1.8 0.0 0.0 2.6 0.0 9.6 0.0 6.3 5.2 9.7 6.6 4.3 13.0 2.6 0.0 4.5 4.6 0.0 0.1 5.6 13.6 6.7 1.0 3.7 0.0 0.0 0.0 3.5 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.0 6.5 6.7 7.5 7.5 8.6 8.6 8.7 8.9 8.1 10.3 4.6 0.0 7.4 362.1 0.2 0.5 4.8 0.4 0.6 1.4 1.4 1.5 1.2 10.0 0.0 12.9 6.2 0.0 0.0 0.1 29.4 2.4 39.5 2.8 9.2 6.1 3.0 2.7 147.4 4.2 0.1 6.4 0.5 8.4 0.0 18.7 10.8 2.5 0.2 1.7 171.1 0.2 0.0 1.6 0.9 16.9 7.5 0.7 7.2 89.0 0.0 16.7 0.0 390.6 76.6 2.0 0.1 12.8 0.4 12.4 0.2 4.5 0.1 2.9 0.0 13.3 4.5 3.2 7.8 0.0 0.9 0.3 0.6 29.6 0.1 1.3 PRMT7 "FLJ10640, KIAA1933" ENSG00000132600 "Protein arginine methyltransferase 7" Q9NVM4 16 68310974-68358584 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044241 Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "HPA044241: AB_2678869" "unprognostic (9.33e-2)" "unprognostic (5.33e-2)" "unprognostic (1.52e-1)" "prognostic favorable (2.31e-5)" "unprognostic (2.92e-2)" "unprognostic (1.95e-1)" "unprognostic (4.12e-2)" "unprognostic (1.22e-1)" "unprognostic (3.74e-1)" "unprognostic (1.19e-1)" "unprognostic (4.74e-3)" "unprognostic (3.09e-2)" "unprognostic (7.72e-2)" "unprognostic (1.75e-1)" "unprognostic (9.23e-2)" "unprognostic (3.57e-1)" "unprognostic (1.31e-1)" 9.7 11.9 8.1 6.2 8.3 4.7 10.5 8.4 10.2 9.8 12.0 10.8 3.2 9.4 3.3 7.5 10.7 4.3 13.2 8.3 8.3 8.6 10.2 5.9 9.4 8.9 8.4 12.1 9.7 4.8 11.1 6.3 8.8 10.5 3.0 4.6 10.0 7.0 21.8 9.8 8.8 4.5 8.3 9.7 8.8 9.8 8.4 14.4 8.6 13.5 5.8 9.7 8.3 8.4 18.1 24.7 13.2 36.1 7.1 7.0 50.8 13.8 6.8 19.5 15.6 79.4 16.1 42.4 29.8 14.0 8.4 22.6 20.4 13.8 12.6 12.7 24.5 8.6 30.8 36.8 7.8 24.3 15.8 11.3 4.9 15.2 14.0 9.3 11.8 18.7 28.1 0.8 10.3 28.2 25.8 36.3 25.3 16.5 18.8 43.7 19.3 25.7 10.7 17.7 19.8 13.2 53.5 16.2 15.7 11.9 25.2 22.2 16.0 14.7 12.9 19.9 17.6 9.6 22.5 41.6 17.1 23.4 16.8 12.3 8.2 7.1 17.4 10.6 20.2 10.9 11.6 14.9 11.8 12.8 16.7 15.4 0.8 21.4 9.5 32.9 14.7 14.3 8.1 8.3 8.4 10.2 8.3 8.3 8.9 8.4 8.8 8.3 8.4 8.4 7.1 19.2 10.6 16.6 12.1 6.9 8.9 12.8 9.1 21.2 10.8 8.8 13.3 8.6 10.0 9.2 54.2 25.4 12.6 28.3 5.9 12.3 4.4 12.9 8.7 7.6 13.2 7.8 25.0 16.1 8.4 10.5 23.4 5.9 7.0 24.9 6.8 8.4 12.2 30.3 25.9 32.4 10.2 7.7 20.6 4.3 11.8 6.2 8.8 12.2 9.1 9.7 13.4 18.6 20.4 23.6 29.8 13.2 6.9 6.7 24.7 7.7 14.5 18.2 13.1 9.9 8.6 6.9 19.3 6.1 6.0 11.6 16.5 10.0 24.1 12.7 PRPS1 "CMTX5, DFN2, DFNX1" ENSG00000147224 "Phosphoribosyl pyrophosphate synthetase 1" P60891 X 107628428-107651993 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Gout, Mental retardation, Neurodegeneration, Neuropathy, Non-syndromic deafness, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043760, HPA051269" Uncertain Approved Vesicles NA NA 320000 "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA043760: AB_2678656, HPA051269: " "unprognostic (4.47e-2)" "unprognostic (6.18e-2)" "unprognostic (2.57e-2)" "unprognostic (4.19e-3)" "unprognostic (2.30e-3)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.46e-1)" "unprognostic (9.73e-2)" "unprognostic (1.91e-2)" "unprognostic (4.11e-2)" "unprognostic (2.85e-2)" "unprognostic (4.57e-2)" "unprognostic (1.29e-1)" "unprognostic (1.25e-2)" "unprognostic (5.25e-2)" 22.9 28.0 33.7 30.2 35.0 58.0 21.0 32.4 36.4 20.0 59.3 19.0 11.0 23.7 14.8 13.7 25.9 13.9 22.2 33.7 39.6 27.6 51.5 21.5 42.7 35.4 39.1 30.2 21.7 27.2 23.2 14.6 37.6 21.3 17.9 30.2 16.3 17.4 49.1 12.3 16.7 29.5 34.2 26.2 15.5 13.4 35.2 52.0 44.1 37.9 45.7 23.6 15.2 34.4 93.5 128.9 56.4 69.9 32.7 26.5 18.6 253.2 55.8 146.0 122.6 55.5 36.6 156.9 111.7 94.9 104.1 36.6 176.0 53.8 148.3 79.9 150.9 84.2 140.0 100.3 28.8 153.1 55.6 28.2 30.6 90.2 56.2 96.7 52.3 108.2 137.4 183.5 69.0 51.0 101.2 113.6 213.5 77.2 141.4 117.6 96.3 125.4 60.7 54.2 96.2 52.5 131.5 77.6 57.3 106.4 36.0 61.7 31.2 93.2 45.0 108.3 109.1 61.8 115.1 172.7 50.1 163.6 61.6 8.8 8.9 22.6 26.0 14.3 30.8 29.3 31.7 32.2 11.4 31.0 36.1 30.7 4.7 28.5 15.7 16.3 35.5 21.1 33.7 35.0 32.4 36.4 33.7 39.6 35.4 39.1 37.6 34.2 35.2 34.4 21.0 6.4 10.0 4.6 44.2 31.1 18.4 13.2 12.0 28.4 8.3 9.4 12.1 15.7 12.6 16.5 4.2 8.8 29.3 3.0 25.4 18.3 1.2 11.5 13.3 18.1 16.2 52.2 4.8 20.2 11.5 22.2 10.2 5.7 26.6 13.2 14.6 57.5 35.3 15.2 10.0 6.5 6.1 18.6 34.8 3.9 14.0 16.8 26.6 6.5 24.9 20.0 27.8 3.5 4.8 19.1 3.7 17.0 35.7 16.2 1.5 29.4 27.1 14.1 0.0 18.1 30.7 3.6 10.9 10.8 22.3 1.8 45.0 19.7 8.0 9.7 PRRX1 "PHOX1, PMX1" ENSG00000116132 "Paired related homeobox 1" P54821 1 170662728-170739421 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 351.7;Endometrial stromal cells: 158.6;Fibroblasts: 180.2;Late spermatids: 390.0;Leydig cells: 256.3;Oligodendrocyte precursor cells: 288.5;Smooth muscle cells: 206.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 367.0;ASC TERT1: 290.5;BJ: 109.7;BJ hTERT+: 213.2;HSkMC: 150.6;U-138 MG: 146.0;U-2197: 140.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051084, HPA063566" Uncertain Supported Nucleoplasm NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA051084: AB_2681338, HPA063566: AB_2732702" "unprognostic (2.03e-1)" "unprognostic (2.00e-1)" "unprognostic (1.09e-1)" "unprognostic (7.00e-2)" "unprognostic (1.24e-1)" "unprognostic (4.97e-2)" "unprognostic (2.52e-2)" "unprognostic (1.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.13e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.60e-10)" "unprognostic (4.23e-3)" "unprognostic (4.48e-2)" "unprognostic (2.68e-3)" "unprognostic (1.69e-3)" 96.3 10.2 14.5 17.7 15.2 0.0 42.9 15.4 13.4 92.0 5.4 5.6 1.1 68.6 20.3 20.1 42.3 34.1 44.2 12.6 26.2 2.3 0.4 21.7 34.6 17.4 18.5 28.2 3.8 7.5 4.9 6.3 16.8 33.5 5.7 0.1 38.5 75.6 51.7 24.1 3.6 52.4 7.9 1.9 3.4 14.2 16.5 18.7 41.6 73.9 36.3 33.0 58.8 15.0 0.0 0.0 2.1 0.0 367.0 290.5 0.1 109.7 213.2 15.0 14.8 0.0 0.1 0.1 0.0 90.2 0.0 0.0 18.5 0.0 4.7 0.0 0.2 0.0 1.6 0.0 1.2 0.0 0.0 150.6 0.0 73.4 0.4 25.7 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.8 0.0 0.0 0.1 146.0 2.6 140.4 16.9 0.0 0.0 0.0 77.3 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 15.2 15.4 13.4 12.6 26.2 17.4 18.5 16.8 7.9 16.5 15.0 49.8 0.0 0.5 114.3 0.3 16.3 0.6 0.1 4.0 0.0 1.3 10.2 29.8 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 1.2 351.7 4.9 158.6 11.4 0.0 0.0 17.4 0.2 0.1 180.2 0.5 3.5 0.0 0.6 0.0 0.0 0.8 0.0 5.5 0.0 0.0 0.0 27.9 390.0 256.3 2.8 14.2 124.6 0.0 0.5 0.0 288.5 0.9 0.7 0.0 104.6 0.4 1.7 0.0 0.1 0.0 0.2 52.6 59.1 206.5 15.4 1.9 1.2 11.8 0.1 2.3 0.6 0.0 1.2 PRSS56 ENSG00000237412 "Serine protease 56" P0CW18 2 232520388-232525716 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 3.0;retina: 5.3;skeletal muscle: 9.7" "Group enriched" "Detected in some" 10 "Early spermatids: 29.0;Muller glia cells: 45.8" "Group enriched" "Detected in many" 4 "cervical cancer: 1.2;colorectal cancer: 2.5;endometrial cancer: 1.4;melanoma: 2.1;urothelial cancer: 4.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "Daudi: 1.0" "Group enriched" "Detected in some" 10 "basal ganglia: 1.8;olfactory bulb: 4.2" "Region enhanced" "Detected in many" "olfactory bulb: 14.9" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (3.26e-1)" "unprognostic (1.98e-2)" "unprognostic (1.31e-1)" "unprognostic (3.73e-3)" "unprognostic (2.28e-1)" "unprognostic (7.15e-2)" "unprognostic (4.64e-2)" "unprognostic (1.20e-1)" 0.0 0.0 0.4 0.0 1.2 0.0 0.0 1.6 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 2.9 1.3 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 5.3 0.0 0.0 9.7 0.0 0.0 0.0 1.1 0.0 0.0 0.8 1.4 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 1.6 3.0 0.1 3.0 2.9 1.3 3.0 1.1 1.4 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 3.6 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PTCH1 "BCNS, NBCCS, PTCH" ENSG00000185920 "Patched 1" Q13635 9 95442980-95517057 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant, Holoprosencephaly, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 26.7" "Cell type enhanced" "Detected in many" "Late spermatids: 237.5;Leydig cells: 191.0;Peritubular cells: 444.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 6.1" "Lineage enriched" "Detected in single" 9 "T-cells: 6.1" "Cell line enhanced" "Detected in many" "NTERA-2: 29.6;WM-115: 71.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013717, HPA075072" Uncertain Approved "Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "CAB013717: , HPA075072: AB_2686733" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (3.16e-1)" "unprognostic (1.79e-2)" "unprognostic (3.22e-2)" "unprognostic (9.01e-2)" "unprognostic (2.13e-1)" "unprognostic (3.54e-3)" "unprognostic (2.63e-1)" "unprognostic (8.66e-3)" "unprognostic (1.52e-2)" "unprognostic (2.82e-1)" "unprognostic (1.13e-6)" "unprognostic (8.63e-2)" "unprognostic (4.40e-2)" "unprognostic (2.76e-1)" "unprognostic (2.82e-1)" 3.0 3.5 9.5 4.0 11.6 0.7 2.8 24.6 5.6 26.7 2.7 11.3 8.1 15.6 2.7 2.9 7.1 8.1 2.9 4.7 17.8 4.6 2.2 5.5 2.2 16.0 12.7 5.0 6.4 2.5 2.1 3.8 8.0 6.8 12.3 8.3 7.5 4.0 3.0 3.2 11.6 2.4 7.0 3.3 12.5 14.5 24.0 2.1 4.7 4.8 3.0 7.2 2.9 4.5 10.1 4.7 20.3 12.9 3.0 5.0 11.4 1.9 1.7 2.2 1.4 4.9 4.8 8.0 3.3 3.8 4.4 22.3 11.7 1.6 1.4 7.9 7.8 0.0 4.8 2.3 2.7 0.2 4.2 4.7 2.4 2.2 1.4 4.3 4.2 3.5 7.3 9.1 1.0 1.9 0.1 3.2 29.6 7.2 1.8 0.0 15.5 4.2 1.6 1.5 13.8 7.0 7.1 6.8 2.9 18.8 1.8 2.1 1.1 2.6 12.9 13.6 1.5 18.0 16.8 5.3 3.8 3.9 71.0 0.0 0.0 0.0 6.1 0.0 3.3 0.7 1.1 2.5 0.0 0.2 1.9 2.2 0.0 0.3 0.0 0.0 1.2 1.7 9.5 11.6 24.6 5.6 4.7 17.8 16.0 12.7 8.0 7.0 24.0 4.5 6.0 0.0 6.4 49.0 3.0 4.0 2.7 3.0 4.6 20.3 3.5 4.6 5.9 25.8 2.7 0.0 41.7 3.0 11.8 2.0 5.9 3.5 88.4 12.2 89.8 5.4 21.7 0.4 15.2 4.2 1.9 27.2 1.1 11.0 1.3 2.6 6.4 2.9 0.8 20.2 10.7 11.0 4.1 0.9 1.2 237.5 191.0 1.4 12.4 4.7 0.8 55.6 54.6 39.7 20.5 2.4 3.1 444.5 3.1 4.9 3.1 1.6 5.5 13.4 39.5 4.8 9.4 4.4 35.5 3.0 4.4 1.4 6.5 71.7 4.7 1.4 PTDSS1 "KIAA0024, PSS1, PSSA" ENSG00000156471 "Phosphatidylserine synthase 1" P48651 8 96261902-96336995 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 10.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016852 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" Nucleoplasm "HPA016852: AB_1855878" "unprognostic (1.44e-1)" "unprognostic (1.71e-1)" "unprognostic (1.08e-1)" "unprognostic (7.89e-3)" "unprognostic (7.48e-2)" "unprognostic (5.68e-3)" "prognostic unfavorable (1.08e-5)" "prognostic unfavorable (9.83e-4)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.19e-1)" "unprognostic (2.29e-3)" "unprognostic (4.78e-2)" "unprognostic (1.79e-1)" "unprognostic (4.08e-2)" "unprognostic (3.55e-2)" 1.6 2.2 1.6 3.4 2.0 4.9 3.1 1.2 2.6 3.5 0.8 3.4 4.1 2.1 2.8 3.7 2.5 3.1 7.2 1.8 1.0 3.7 4.6 2.6 5.6 0.5 0.6 3.6 2.7 8.0 0.6 4.6 1.3 1.9 2.9 0.9 2.0 3.5 2.9 3.2 3.2 3.6 0.2 2.6 1.4 1.9 2.0 3.6 4.5 3.0 5.2 2.6 1.1 1.4 14.9 11.6 2.0 5.5 4.2 8.5 3.4 10.6 15.5 10.6 7.5 4.6 4.2 24.9 9.5 10.5 2.1 6.0 14.1 11.1 16.1 12.5 10.3 24.5 19.8 2.5 4.3 17.8 8.1 7.2 10.9 14.4 10.2 2.7 7.0 7.6 12.5 12.3 9.7 4.4 14.0 3.0 3.1 5.1 11.1 10.9 10.1 18.8 5.7 12.5 8.6 3.5 3.9 3.4 1.4 2.3 8.2 6.3 11.8 9.1 5.5 6.3 12.3 2.5 13.3 11.8 5.7 19.3 7.5 10.5 2.6 1.5 1.7 1.6 2.5 1.7 2.8 2.2 4.0 2.2 2.5 1.8 0.9 3.2 1.7 1.2 1.7 6.7 1.6 2.0 1.2 2.6 1.8 1.0 0.5 0.6 1.3 0.2 2.0 1.4 12.4 19.2 9.1 8.8 50.5 31.6 18.9 22.6 42.7 10.2 22.9 18.4 94.5 14.3 15.6 11.0 10.4 78.4 23.6 11.9 1.9 20.5 60.1 6.6 9.1 22.9 5.4 38.3 29.3 44.9 54.1 18.0 14.8 9.3 32.4 17.6 34.2 32.1 45.9 5.0 29.2 17.1 10.2 45.3 31.5 52.2 23.3 36.0 19.6 15.9 39.3 4.7 29.9 21.1 8.7 23.9 11.9 25.9 45.5 21.4 16.6 19.0 5.2 4.7 0.0 13.8 15.8 12.1 18.8 33.1 33.5 80.9 34.3 14.6 34.8 16.3 PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863625-87971930 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 60.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004076, HPA031335" Approved Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "CAB004076: AB_390810, HPA031335: AB_2797221" "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" 64.0 25.4 17.8 18.6 19.3 12.9 47.6 34.5 23.4 54.8 15.6 28.1 12.9 27.4 18.6 28.3 35.2 15.6 29.7 20.4 18.4 22.6 39.2 39.5 21.4 16.6 17.8 28.0 33.2 11.9 17.3 30.5 16.4 26.3 14.6 30.0 19.6 16.5 23.7 25.9 24.5 22.2 14.5 40.0 25.6 28.2 19.7 31.8 26.1 14.0 16.5 28.1 38.4 17.6 23.5 10.8 12.3 11.2 28.5 19.7 10.9 12.5 28.0 14.5 20.4 10.9 28.0 28.1 8.0 20.9 8.3 14.1 16.6 14.3 22.8 14.1 4.7 9.3 28.5 13.8 30.1 31.9 15.3 13.5 38.7 18.0 23.7 60.3 20.8 17.7 7.0 72.6 13.5 18.1 17.8 56.3 4.6 19.9 0.0 27.6 6.4 20.8 22.9 13.4 4.5 19.9 16.6 7.9 23.0 9.7 21.9 45.2 17.9 44.6 10.8 18.3 10.1 23.9 32.9 30.7 14.6 29.2 2.9 21.3 14.2 25.8 6.8 21.8 7.2 7.9 7.2 6.6 10.3 6.8 8.3 8.3 60.5 8.9 15.6 8.2 7.0 4.5 17.8 19.3 34.5 23.4 20.4 18.4 16.6 17.8 16.4 14.5 19.7 17.6 67.2 35.3 63.3 83.6 48.3 56.1 57.4 31.5 47.3 113.0 49.4 41.9 46.5 57.2 31.2 29.5 39.6 25.8 64.4 57.7 33.2 24.7 70.1 40.0 114.5 56.0 31.2 52.0 141.0 30.0 62.2 79.3 39.8 33.6 25.4 39.6 53.9 64.1 35.0 45.4 132.4 44.7 12.2 206.1 97.2 92.1 56.8 105.2 62.2 196.8 101.5 61.6 44.3 139.2 95.7 30.6 39.7 54.5 39.3 45.1 50.1 38.0 31.2 61.2 92.1 66.4 170.7 33.5 25.4 45.2 60.1 57.3 46.3 44.7 46.1 64.0 PTH1R "PTHR, PTHR1" ENSG00000160801 "Parathyroid hormone 1 receptor" Q03431 3 46877721-46903799 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "kidney: 586.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 95.9;Extravillous trophoblasts: 60.8;Proximal tubular cells: 324.8;Sertoli cells: 138.1" "Group enriched" "Detected in many" 4 "renal cancer: 18.8;testis cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "RPTEC TERT1: 116.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075879 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA075879: " "unprognostic (1.26e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-5)" "unprognostic (7.46e-2)" "unprognostic (3.46e-1)" "unprognostic (5.02e-2)" "unprognostic (3.84e-3)" "unprognostic (5.47e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (7.51e-2)" "unprognostic (8.44e-2)" "prognostic favorable (6.79e-6)" "unprognostic (4.22e-3)" "unprognostic (1.50e-1)" "unprognostic (1.35e-4)" "unprognostic (6.62e-3)" 32.5 72.2 45.0 1.1 43.8 0.0 20.2 45.7 60.8 43.8 38.0 10.3 1.2 19.1 2.7 3.7 20.3 3.5 33.0 42.6 43.5 586.8 84.6 25.6 2.4 46.5 44.9 22.2 7.6 1.2 5.9 16.0 46.7 12.4 0.6 0.7 2.7 3.5 7.7 9.8 9.6 2.6 44.5 54.4 7.6 10.3 46.2 0.4 6.5 2.2 0.4 12.3 20.3 43.3 0.0 0.2 0.2 0.2 15.9 1.9 0.2 0.4 0.2 0.3 0.2 0.4 0.0 0.0 1.6 0.1 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.0 15.5 0.0 0.1 0.0 0.2 0.1 0.0 0.0 2.6 0.1 0.1 0.0 0.3 2.1 0.0 0.1 0.1 5.3 0.0 116.9 0.0 0.2 0.7 0.0 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.0 43.8 45.7 60.8 42.6 43.5 46.5 44.9 46.7 44.5 46.2 43.3 4.6 0.0 0.0 17.3 2.5 1.3 0.1 0.0 0.6 1.5 2.9 0.4 5.0 2.8 0.0 33.1 0.0 0.6 0.1 0.0 95.9 0.0 11.6 0.6 20.5 4.1 0.0 8.0 1.6 0.5 60.8 9.6 0.0 0.6 0.0 0.1 17.2 0.7 2.0 1.7 2.8 0.0 0.0 1.3 2.8 32.5 5.9 2.1 0.0 1.9 0.0 3.2 0.0 1.0 0.3 0.3 0.0 2.2 0.0 0.0 0.0 324.8 0.0 1.7 138.1 6.5 21.7 0.9 2.7 0.0 0.9 0.8 2.0 0.3 0.0 0.1 PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 254.0;Basal squamous epithelial cells: 93.9;Breast glandular cells: 105.4;Breast myoepithelial cells: 56.3;Club cells: 77.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HaCaT: 291.3;HBEC3-KT: 359.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: AB_10794631" "unprognostic (1.67e-1)" "unprognostic (5.26e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.60e-2)" "unprognostic (1.18e-1)" "unprognostic (5.16e-2)" "unprognostic (4.09e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-9)" "unprognostic (2.01e-2)" "unprognostic (1.34e-1)" "unprognostic (5.23e-3)" "unprognostic (7.87e-3)" 3.1 0.8 1.8 1.2 2.3 0.0 20.1 0.6 3.2 13.6 10.2 3.3 2.3 10.7 1.1 16.2 1.5 7.5 4.2 4.1 3.2 0.4 0.2 1.2 1.1 4.0 8.1 1.8 1.7 22.8 2.9 3.0 0.4 5.2 1.6 0.2 8.5 2.4 0.7 2.0 1.6 3.0 0.2 3.6 1.8 1.3 8.6 0.4 1.8 1.7 1.0 9.2 15.2 0.8 1.7 9.9 0.0 0.0 2.9 2.8 0.1 0.3 1.0 0.5 1.3 0.3 7.9 0.0 0.5 2.6 9.1 291.3 1.3 359.8 0.1 7.4 1.7 0.5 1.8 0.1 0.8 0.1 0.4 0.2 19.7 9.1 34.4 0.9 11.2 0.1 0.0 0.4 0.2 0.1 0.1 0.0 1.4 0.4 16.7 0.1 1.5 0.6 34.3 0.3 0.2 0.1 16.4 0.1 2.1 11.5 0.5 0.1 5.6 1.6 8.9 5.1 77.8 4.7 0.1 12.1 7.5 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.8 2.3 0.6 3.2 4.1 3.2 4.0 8.1 0.4 0.2 8.6 0.8 1.4 0.0 0.0 0.7 0.4 4.6 1.9 254.0 93.9 0.3 105.4 56.3 0.4 0.0 77.5 0.0 0.0 0.0 0.5 0.0 0.0 3.5 5.9 0.9 4.7 4.5 0.0 0.0 0.6 8.9 0.0 13.6 0.0 0.8 0.0 2.6 0.4 0.2 0.0 0.0 11.2 0.0 4.1 0.3 1.3 2.7 0.9 0.6 23.2 1.0 0.6 1.8 0.0 0.0 0.2 8.6 0.0 0.0 6.2 0.5 0.0 0.3 14.8 0.5 6.6 8.0 6.7 3.6 0.2 7.9 1.4 0.0 0.5 0.2 0.0 0.2 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase non-receptor type 11" Q06124 12 112418351-112509918 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli rim,Actin filaments,Cytosol" NA NA 74000 "Cluster 6: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Nucleoli rim" "Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 62.9 36.6 74.6 34.7 91.7 46.3 37.6 72.7 115.7 37.9 38.4 32.5 27.6 37.8 28.7 38.9 24.3 29.4 68.7 66.1 85.6 39.7 53.0 34.4 35.6 79.0 84.1 26.2 31.6 53.4 16.1 38.0 85.7 35.2 30.6 51.8 25.9 42.4 75.1 32.1 26.1 45.7 83.4 26.7 30.4 18.2 81.7 35.5 46.8 64.0 32.5 40.1 23.5 106.3 116.9 107.6 77.0 73.4 109.7 106.1 92.7 136.4 148.2 105.5 78.5 107.7 43.4 124.5 69.4 127.4 66.7 68.1 100.1 121.6 173.8 93.1 85.0 181.5 102.6 59.8 109.2 145.8 108.0 86.6 119.6 113.6 159.8 101.3 88.7 92.0 140.2 41.3 103.3 83.2 101.0 69.7 94.1 112.3 73.4 102.4 114.6 70.5 97.3 126.7 53.3 66.1 133.7 99.8 85.2 77.6 114.8 97.8 108.1 122.9 110.0 74.2 121.8 79.4 141.6 120.2 102.2 99.7 117.7 32.2 11.7 16.8 14.8 10.2 14.0 18.1 13.3 12.4 13.6 20.8 15.3 11.9 10.7 12.6 13.7 18.3 10.9 7.2 74.6 91.7 72.7 115.7 66.1 85.6 79.0 84.1 85.7 83.4 81.7 106.3 49.0 60.9 68.2 27.7 25.8 25.6 39.9 25.3 20.5 29.9 40.5 32.4 131.6 24.3 41.8 36.8 16.7 23.5 34.2 25.4 33.2 37.5 63.1 31.3 92.6 46.2 13.1 21.7 67.6 42.8 25.3 35.8 21.9 40.9 28.4 33.1 26.0 101.5 26.8 13.5 54.7 22.0 18.3 33.3 21.6 28.5 51.6 31.8 14.2 40.3 31.1 59.8 29.9 32.6 73.0 59.3 19.6 79.7 37.0 73.4 16.6 39.8 23.5 22.2 32.9 58.2 49.2 7.1 6.6 37.5 27.4 35.2 31.7 30.5 22.2 66.8 PTPN14 PEZ ENSG00000152104 "Protein tyrosine phosphatase non-receptor type 14" Q15678 1 214348700-214552449 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011469, HPA053864, CAB069441" Uncertain Supported Nucleoplasm NA NA "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB011469: AB_299202, CAB069441: , HPA053864: AB_2682281" "unprognostic (1.54e-1)" "unprognostic (8.19e-2)" "unprognostic (5.42e-5)" "unprognostic (1.42e-1)" "unprognostic (2.91e-1)" "unprognostic (5.97e-2)" "unprognostic (1.26e-1)" "unprognostic (1.58e-1)" "unprognostic (2.84e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.29e-4)" "unprognostic (7.43e-2)" "unprognostic (8.34e-3)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "unprognostic (4.81e-3)" 7.5 8.0 3.7 1.8 1.5 0.2 10.6 1.5 3.7 5.2 13.4 7.6 0.9 8.2 2.5 6.0 7.3 3.3 6.0 3.3 0.8 8.2 0.7 4.6 1.3 2.4 2.4 6.6 4.3 3.3 1.8 7.8 2.1 6.7 2.3 0.6 6.5 6.6 19.8 16.2 2.8 7.9 1.4 3.5 4.5 3.9 4.2 2.1 5.3 10.2 1.8 5.6 5.6 1.9 21.1 9.2 7.2 10.6 12.3 20.9 21.6 23.2 21.3 17.3 14.4 18.8 10.7 0.1 25.3 53.6 10.0 18.1 10.0 25.7 29.0 0.2 7.7 1.9 26.6 3.5 22.2 0.2 1.0 15.6 26.1 30.0 47.4 28.1 33.8 0.6 0.1 0.2 41.8 2.3 0.2 0.2 16.2 3.7 9.9 0.3 36.3 0.1 30.6 10.5 0.1 1.7 28.7 18.4 11.6 25.1 18.4 0.7 61.4 40.3 15.9 14.6 33.3 1.2 0.1 0.2 21.6 0.3 34.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 3.7 1.5 1.5 3.7 3.3 0.8 2.4 2.4 2.1 1.4 4.2 1.9 60.3 73.7 12.6 47.3 1.3 56.5 32.1 39.4 45.5 0.6 20.3 29.8 20.5 14.3 32.7 29.5 0.0 38.8 1.3 1.0 7.9 12.9 8.8 42.5 25.9 53.5 3.5 0.0 47.9 11.0 14.2 20.8 9.2 55.2 1.3 13.5 40.0 0.9 4.5 0.0 6.0 4.1 4.1 1.5 7.7 4.4 26.1 2.4 10.6 91.8 0.3 3.9 3.1 39.2 2.1 31.2 0.3 29.3 1.6 30.6 0.3 14.4 18.5 1.3 19.7 38.0 20.1 1.2 10.6 18.3 36.1 24.2 3.7 46.3 2.9 28.9 PTPN23 "DKFZP564F0923, HD-PTP, KIAA1471" ENSG00000076201 "Protein tyrosine phosphatase non-receptor type 23" Q9H3S7 3 47381011-47413435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016845 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear bodies" Vesicles "HPA016845: AB_1855926" "unprognostic (1.17e-3)" "unprognostic (8.68e-2)" "unprognostic (2.56e-1)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (6.24e-2)" "unprognostic (1.07e-3)" "unprognostic (2.07e-2)" "unprognostic (9.55e-2)" "unprognostic (7.12e-2)" "unprognostic (5.67e-2)" "unprognostic (4.34e-2)" "prognostic favorable (1.82e-4)" "unprognostic (3.05e-2)" "unprognostic (4.40e-1)" "unprognostic (9.53e-2)" "unprognostic (4.68e-2)" 18.5 19.1 6.2 12.6 9.2 14.7 17.4 5.8 10.5 23.3 5.1 16.3 14.3 20.9 7.5 19.0 19.2 8.4 13.2 7.1 7.2 17.5 14.0 18.7 9.1 8.8 7.2 23.5 20.2 23.5 30.9 11.6 8.5 18.7 6.5 8.5 20.0 11.4 30.0 26.4 18.4 8.8 5.5 20.0 16.1 15.6 7.7 8.0 27.1 8.9 7.3 18.5 20.4 14.4 21.5 29.9 16.4 21.4 21.0 16.0 15.8 19.2 18.9 17.5 14.8 25.0 20.7 15.1 17.2 21.9 31.2 19.0 14.3 20.8 8.5 14.3 15.1 21.0 22.2 24.0 23.0 12.3 27.5 21.4 20.9 22.9 23.2 12.4 21.7 12.5 15.9 20.3 19.0 30.2 11.5 10.4 17.5 14.9 20.1 7.2 7.9 18.5 13.2 40.9 8.6 20.6 17.1 35.6 13.6 9.8 20.3 12.0 22.4 26.7 22.2 37.7 27.5 28.8 20.4 8.7 29.0 11.6 19.5 0.8 0.2 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.2 0.3 0.3 6.2 9.2 5.8 10.5 7.1 7.2 8.8 7.2 8.5 5.5 7.7 14.4 11.1 9.6 7.0 17.0 8.2 8.0 5.2 6.9 13.6 11.7 9.5 8.0 8.7 8.6 9.5 5.5 14.6 10.6 11.0 15.7 1.9 10.5 2.1 10.3 13.7 12.4 7.3 2.5 9.8 8.9 7.9 9.1 26.5 21.1 2.5 14.9 11.4 12.7 13.9 16.8 12.0 16.3 20.3 10.4 5.5 3.1 19.3 9.5 12.4 7.5 8.7 8.8 6.2 9.5 14.3 13.5 10.4 13.5 15.4 9.3 14.6 9.4 12.6 14.2 6.6 10.2 8.8 13.6 13.3 13.2 10.9 9.3 8.9 9.4 12.8 8.2 PTRH2 "BIT1, CFAP37, CGI-147, PTH2" ENSG00000141378 "Peptidyl-tRNA hydrolase 2" Q9Y3E5 17 59674636-59707626 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Apoptosis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012897 Supported Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA012897: AB_1855949" "unprognostic (2.26e-1)" "unprognostic (2.80e-2)" "unprognostic (1.02e-2)" "unprognostic (3.89e-2)" "unprognostic (1.31e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (6.38e-2)" "unprognostic (2.02e-1)" "unprognostic (9.59e-3)" "unprognostic (2.72e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.01e-8)" "unprognostic (5.43e-3)" "unprognostic (6.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.49e-2)" 20.8 25.9 24.3 17.3 25.1 14.5 27.6 25.0 31.9 19.7 23.6 24.1 15.3 18.8 48.5 18.1 18.4 18.2 14.5 25.1 26.1 18.5 45.7 14.7 19.0 25.9 26.1 16.9 19.5 18.6 14.1 18.6 26.7 20.7 27.5 10.2 15.9 18.6 25.0 15.7 13.2 22.9 24.8 17.5 16.1 19.5 24.9 17.3 16.2 20.9 24.1 44.0 11.8 27.4 75.9 142.9 44.3 40.8 84.8 72.6 47.4 70.6 63.8 60.7 89.0 94.1 57.7 54.1 105.0 60.9 101.1 73.3 98.4 93.8 89.4 104.2 133.2 96.7 72.3 176.2 129.4 86.0 52.5 82.0 120.9 93.9 108.5 42.8 102.5 37.4 111.3 58.2 92.4 187.9 74.2 71.2 38.0 194.5 113.4 39.1 74.8 80.7 103.7 109.2 57.9 74.2 36.7 39.6 91.5 50.7 93.1 61.1 67.2 77.8 77.8 47.1 77.9 73.6 91.9 82.3 50.7 54.4 60.4 6.1 69.0 2.9 22.7 67.4 30.9 43.1 26.3 25.7 50.0 33.1 37.4 27.0 29.0 34.8 86.0 59.4 34.0 37.9 24.3 25.1 25.0 31.9 25.1 26.1 25.9 26.1 26.7 24.8 24.9 27.4 21.4 16.0 13.6 5.5 18.7 36.7 50.1 48.1 27.9 4.1 17.1 22.4 15.4 11.5 51.6 11.0 4.2 26.8 13.0 8.9 11.7 27.2 22.1 23.4 33.1 22.5 6.7 17.9 9.8 25.6 25.0 29.7 17.3 24.1 22.8 12.8 12.8 31.5 16.9 8.4 9.1 10.3 22.4 9.7 17.2 12.0 17.4 14.6 14.2 2.8 11.4 7.2 13.4 7.5 11.5 28.8 12.3 9.8 24.8 35.1 10.0 16.5 33.3 3.4 13.1 25.4 32.2 33.4 13.3 21.3 35.7 31.7 12.6 22.4 16.7 37.5 PUF60 "FIR, RoBPI, SIAHBP1" ENSG00000179950 "Poly(U) binding splicing factor 60" Q9UHX1 8 143816344-143829352 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "DNA-binding, Repressor, Ribonucleoprotein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 332.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045733, HPA052096, HPA059714" Enhanced Enhanced Nucleoplasm NA NA 70000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA045733: AB_10960503, HPA052096: AB_2681722, HPA059714: AB_2684110" "unprognostic (3.49e-2)" "unprognostic (8.78e-2)" "unprognostic (2.66e-1)" "unprognostic (4.05e-2)" "unprognostic (1.81e-2)" "unprognostic (3.47e-2)" "unprognostic (1.51e-2)" "unprognostic (4.34e-3)" "unprognostic (2.64e-2)" "unprognostic (1.07e-2)" "unprognostic (1.75e-1)" "unprognostic (5.45e-2)" "unprognostic (2.36e-2)" "unprognostic (2.64e-2)" "unprognostic (7.00e-2)" "unprognostic (2.28e-2)" "unprognostic (3.42e-2)" 71.6 73.5 7.9 11.0 7.6 39.6 75.5 8.1 22.9 71.4 5.3 84.8 22.3 84.9 5.9 84.9 76.3 7.3 88.5 7.8 15.4 82.8 124.3 64.0 17.7 12.2 11.6 57.2 62.9 11.7 71.0 19.2 14.1 67.2 5.8 1.3 63.3 17.8 125.5 108.7 69.5 10.5 7.3 72.3 73.2 70.8 14.5 15.9 59.8 9.0 9.7 74.5 68.6 12.4 95.7 211.5 36.7 31.3 16.6 15.6 62.7 74.4 27.4 70.3 75.1 95.4 103.9 89.4 71.2 58.9 52.8 83.0 86.5 91.4 3.6 91.4 147.7 110.2 117.0 106.3 60.4 38.5 70.0 45.4 61.8 89.8 26.9 21.1 69.0 92.1 88.7 37.4 20.5 332.5 156.1 26.4 77.8 63.3 191.6 84.2 42.9 91.8 19.5 91.8 71.5 80.3 101.6 40.4 77.7 9.1 116.7 21.4 79.0 72.9 176.2 85.7 98.6 66.7 103.9 109.7 70.7 73.3 71.9 90.8 112.6 99.8 129.0 133.7 139.3 116.8 103.1 128.6 127.1 135.9 98.6 113.1 58.8 132.6 137.6 76.8 139.0 193.9 7.9 7.6 8.1 22.9 7.8 15.4 12.2 11.6 14.1 7.3 14.5 12.4 70.2 38.5 46.4 21.5 64.7 107.7 102.1 197.4 65.4 62.8 51.3 67.9 63.7 51.5 103.0 29.5 29.2 146.6 56.4 98.0 92.0 110.7 20.5 65.6 55.3 67.3 66.9 65.0 8.2 89.8 134.3 68.4 74.9 60.3 55.8 75.0 41.7 76.8 101.1 43.7 8.3 75.9 118.0 44.0 62.3 47.8 64.0 52.3 90.7 6.5 105.2 182.6 81.4 9.5 23.7 98.2 91.4 59.0 52.7 83.0 91.9 118.1 85.4 64.8 65.7 57.1 122.9 104.2 128.5 63.1 107.1 173.3 74.2 99.3 97.7 81.2 PXDN "D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN" ENSG00000130508 Peroxidasin Q92626 2 1631887-1744852 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.1;Endometrial stromal cells: 99.4;Endothelial cells: 95.1;Hepatic stellate cells: 71.4;Skeletal myocytes: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 323.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA012375 Approved "Secreted to extracellular matrix" NA NA 9100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA012375: AB_1855965" "unprognostic (4.37e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (8.16e-3)" "unprognostic (1.91e-1)" "unprognostic (1.92e-2)" "unprognostic (3.15e-3)" "unprognostic (6.50e-3)" "unprognostic (1.34e-2)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.18e-1)" "unprognostic (7.33e-3)" "unprognostic (5.54e-3)" 59.5 5.5 4.1 24.3 3.5 0.9 33.7 1.9 4.1 18.2 27.5 36.1 7.9 32.8 4.0 4.9 18.0 22.7 22.7 3.1 7.7 9.0 12.4 27.6 5.0 4.2 6.2 32.7 3.8 3.0 11.7 33.4 4.7 17.5 8.7 5.2 13.6 11.1 7.7 6.9 16.3 61.8 2.6 10.0 13.2 6.4 5.2 2.1 8.4 11.5 2.1 33.8 13.5 3.4 39.9 13.9 72.0 0.1 198.3 180.9 54.6 231.4 182.3 99.0 107.9 0.1 0.5 0.0 323.8 230.3 4.5 8.3 0.3 142.3 125.5 0.6 2.4 0.0 139.3 0.0 196.4 0.6 0.0 200.7 41.0 112.2 83.8 299.5 247.0 35.9 0.1 0.0 142.6 23.6 6.8 8.0 58.3 0.0 52.3 13.2 250.8 0.6 115.9 0.1 0.2 131.9 0.2 73.6 0.4 142.9 27.0 0.9 242.4 162.8 79.7 6.2 180.7 0.2 205.4 1.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.1 3.5 1.9 4.1 3.1 7.7 4.2 6.2 4.7 2.6 5.2 3.4 79.1 6.4 2.3 2.6 0.4 2.9 2.8 12.8 0.6 2.5 17.5 14.1 5.8 17.2 7.0 1.8 0.0 0.6 0.2 0.3 0.0 10.4 33.4 4.2 99.4 95.1 1.8 0.0 6.6 0.0 11.3 45.2 0.0 3.4 1.3 43.7 71.4 1.8 1.9 0.0 7.3 1.3 20.3 5.7 4.4 40.7 26.8 0.7 7.2 8.4 0.6 10.0 1.0 55.8 0.7 0.5 0.1 15.1 0.0 14.0 0.0 0.2 6.7 0.8 46.0 120.1 51.1 22.0 16.0 0.5 2.8 1.4 1.0 33.3 0.5 1.4 PYCR1 P5C ENSG00000183010 "Pyrroline-5-carboxylate reductase 1" P32322 17 81932384-81942412 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis, Stress response" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 111.8;salivary gland: 121.1" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 63.8;Extravillous trophoblasts: 63.8;Intestinal goblet cells: 83.4;Prostatic glandular cells: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 4.2" "Group enriched" "Detected in many" 8 "B-cells: 4.2;dendritic cells: 1.9;T-cells: 1.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047660 Approved NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 30: Mammary glandular cells - Lactation" "HPA047660: AB_2680115" "unprognostic (1.12e-2)" "unprognostic (2.13e-2)" "unprognostic (7.04e-2)" "unprognostic (7.27e-2)" "unprognostic (9.86e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (2.33e-4)" "unprognostic (2.80e-1)" "unprognostic (9.36e-3)" "unprognostic (6.65e-2)" "unprognostic (3.02e-3)" "unprognostic (7.12e-2)" "prognostic unfavorable (7.33e-12)" "unprognostic (7.98e-2)" "unprognostic (1.56e-1)" "unprognostic (1.12e-2)" "unprognostic (5.92e-2)" 7.5 4.1 13.8 13.8 14.1 12.5 17.4 13.2 15.2 24.2 9.6 23.8 14.3 10.6 2.5 18.7 9.7 8.9 10.0 12.5 14.4 6.3 8.7 13.6 6.9 16.1 13.9 7.5 111.8 1.9 21.6 11.7 14.8 25.5 14.4 0.9 121.1 7.8 11.5 6.3 12.5 12.2 12.7 8.0 42.4 15.1 15.8 2.6 8.5 2.0 6.7 12.0 10.3 14.2 107.4 111.9 62.7 228.3 36.7 69.0 117.2 176.0 85.4 54.7 73.7 129.3 116.9 163.2 38.0 188.9 33.3 45.8 148.2 67.1 32.7 42.4 18.6 96.5 56.5 350.8 213.8 64.8 70.6 58.5 129.8 68.2 178.7 64.8 95.5 129.4 314.0 147.2 35.1 376.4 68.1 49.5 52.8 291.9 170.1 0.9 105.6 205.5 49.9 38.7 237.7 167.2 36.9 203.6 219.5 46.3 210.0 117.1 70.1 53.7 201.8 91.4 66.3 183.4 141.3 156.2 57.2 0.8 178.1 0.0 0.1 0.0 0.2 0.2 0.4 4.2 0.7 0.2 1.3 1.8 1.6 1.2 0.0 0.3 0.0 1.9 0.3 1.1 13.8 14.1 13.2 15.2 12.5 14.4 16.1 13.9 14.8 12.7 15.8 14.2 2.3 0.0 3.9 2.3 9.1 7.0 11.4 12.2 4.6 0.3 50.6 29.5 0.6 1.5 7.2 3.7 0.0 2.0 2.3 17.2 0.0 13.3 13.8 3.4 14.6 4.7 10.8 27.8 0.9 63.8 63.8 24.9 35.7 13.8 4.5 13.9 2.5 1.8 5.0 3.3 1.4 83.4 8.2 0.0 5.4 32.4 7.5 0.8 8.8 0.0 0.7 0.5 0.0 3.5 0.7 48.0 19.5 3.8 34.1 59.6 1.2 1.9 1.3 0.2 0.0 3.3 17.8 28.2 16.9 8.0 6.0 3.8 1.9 15.5 43.1 8.6 QARS1 QARS ENSG00000172053 "Glutaminyl-tRNA synthetase 1" P47897 3 49095932-49105130 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 55.5;Cytotrophoblasts: 193.9;Extravillous trophoblasts: 156.7;Hofbauer cells: 96.1;Syncytiotrophoblasts: 187.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036986, HPA036987" Enhanced Enhanced Cytosol No No 58000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA036986: AB_10672344, HPA036987: AB_2675418" "prognostic favorable (1.43e-4)" "unprognostic (1.96e-1)" "unprognostic (7.31e-2)" "unprognostic (1.10e-2)" "unprognostic (5.13e-3)" "unprognostic (6.62e-3)" "unprognostic (6.53e-3)" "unprognostic (1.52e-2)" "unprognostic (1.17e-1)" "unprognostic (2.51e-1)" "unprognostic (4.33e-1)" "unprognostic (9.14e-2)" "prognostic favorable (5.60e-6)" "unprognostic (2.73e-3)" "unprognostic (1.65e-1)" "unprognostic (2.74e-2)" "unprognostic (3.11e-1)" 61.1 58.8 20.0 57.2 21.3 96.6 89.5 23.5 18.5 58.3 34.2 104.8 101.6 45.5 58.5 102.5 71.0 48.3 72.0 18.4 21.1 57.1 51.1 52.3 75.8 23.8 21.0 69.0 73.9 78.1 33.0 76.7 23.0 60.4 121.0 21.4 103.2 61.1 156.1 105.0 84.6 60.2 22.7 60.1 75.0 30.0 23.0 92.3 53.2 146.2 118.8 72.8 58.1 24.6 95.9 97.8 128.0 197.4 146.4 180.8 159.2 90.5 188.2 160.5 152.9 123.0 113.5 257.1 61.4 136.7 95.3 119.9 166.3 137.8 111.4 78.2 148.0 206.4 156.0 216.1 91.2 187.2 130.9 184.8 123.1 127.4 108.1 175.3 184.7 144.6 95.3 112.4 118.0 89.2 130.7 154.9 116.1 159.0 122.9 76.0 123.7 200.6 108.5 163.9 48.7 161.6 85.4 211.0 147.8 122.7 184.4 205.5 137.6 82.8 127.3 131.7 117.9 111.9 176.5 142.9 88.4 156.3 60.3 30.7 84.3 25.8 44.5 104.1 57.4 62.2 54.1 47.0 127.0 49.9 46.6 49.0 8.0 71.8 94.5 57.4 82.1 81.2 20.0 21.3 23.5 18.5 18.4 21.1 23.8 21.0 23.0 22.7 23.0 24.6 15.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 0.0 0.0 0.0 0.0 193.9 11.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 156.7 14.7 0.0 0.0 0.0 0.0 0.0 0.0 96.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 187.0 2.0 0.0 0.0 0.0 QRICH1 "AB-DIP, FLJ20259, VERBRAS" ENSG00000198218 "Glutamine rich 1" Q2TAL8 3 49029707-49094363 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Unfolded protein response" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037677, HPA037678" Approved Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA037677: AB_10671883, HPA037678: AB_2675603" "unprognostic (2.38e-2)" "unprognostic (2.05e-1)" "unprognostic (8.29e-2)" "unprognostic (1.67e-1)" "unprognostic (2.41e-1)" "unprognostic (3.14e-2)" "unprognostic (2.77e-3)" "unprognostic (6.94e-2)" "unprognostic (2.82e-2)" "prognostic favorable (7.46e-4)" "unprognostic (1.12e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-3)" "unprognostic (5.06e-2)" "unprognostic (3.84e-1)" "unprognostic (1.76e-1)" "unprognostic (1.06e-1)" 29.8 27.9 15.4 30.5 17.0 61.0 27.8 25.3 20.2 25.8 16.0 25.9 26.3 28.6 25.9 30.0 27.6 25.2 26.0 16.9 14.8 21.3 23.5 27.8 40.1 14.7 13.2 34.0 26.0 33.2 24.8 27.0 14.6 25.8 25.2 30.4 28.3 26.3 34.8 35.4 31.0 28.9 13.2 35.8 25.9 44.5 13.3 51.9 25.7 32.4 41.9 26.8 23.7 16.9 41.4 39.6 78.6 35.6 48.2 45.8 48.2 48.4 60.3 75.6 70.7 44.3 50.8 65.6 29.1 58.9 62.8 33.5 69.0 63.0 64.8 57.8 45.1 65.5 52.9 37.8 43.1 57.9 75.0 53.3 47.4 74.8 46.6 46.2 60.3 62.7 45.0 58.6 51.6 31.8 84.9 41.4 62.3 43.7 48.9 43.3 40.3 55.4 47.6 63.2 29.9 58.9 54.9 47.7 39.7 59.3 42.4 65.5 52.5 49.0 55.1 43.7 69.8 54.2 66.6 82.2 44.0 55.2 57.2 21.3 15.6 19.1 18.1 18.9 21.5 16.6 17.3 20.6 18.5 16.6 18.3 22.0 11.7 18.1 33.0 13.5 19.8 14.3 15.4 17.0 25.3 20.2 16.9 14.8 14.7 13.2 14.6 13.2 13.3 16.9 21.8 9.6 18.9 19.6 30.5 22.2 13.7 16.0 17.1 13.6 20.6 17.7 21.1 14.3 17.9 20.2 22.9 25.7 28.2 16.6 1.9 15.9 15.8 19.8 20.7 19.6 25.9 22.5 37.9 14.0 27.8 20.3 23.9 27.5 16.5 20.0 18.9 20.4 19.7 11.8 39.1 20.6 10.2 25.3 18.3 10.9 22.4 19.5 12.4 14.0 22.3 12.5 15.5 24.6 25.5 18.6 10.5 30.9 39.7 18.0 14.4 10.1 15.2 17.6 6.6 21.9 25.3 52.4 27.8 24.5 22.6 36.8 28.5 17.0 16.8 15.5 RAB11B H-YPT3 ENSG00000185236 "RAB11B, member RAS oncogene family" Q15907 19 8389981-8404434 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 334.5" "Low region specificity" "Detected in all" HPA054396 Approved "Vesicles,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" "Vesicles, Centriolar satellite" "HPA054396: AB_2682474" "unprognostic (5.81e-3)" "prognostic favorable (2.08e-4)" "unprognostic (1.13e-2)" "unprognostic (1.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.61e-3)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-1)" "unprognostic (4.78e-2)" "prognostic favorable (7.58e-5)" "unprognostic (1.23e-1)" "prognostic favorable (2.06e-4)" "unprognostic (3.66e-1)" "unprognostic (3.87e-1)" "unprognostic (8.85e-2)" "unprognostic (3.29e-3)" 102.1 96.7 97.6 59.2 113.2 68.7 113.8 118.5 131.4 105.3 67.4 99.1 76.5 101.3 23.0 95.2 97.3 51.2 167.9 91.7 102.0 129.3 133.8 98.2 58.8 130.9 121.8 107.6 129.7 49.0 115.7 53.9 127.7 111.7 23.4 38.2 104.3 49.3 119.6 101.8 97.2 27.8 108.1 118.7 118.0 64.5 120.4 44.1 210.0 36.6 28.2 99.5 94.2 127.3 93.1 115.3 83.1 75.9 43.7 39.9 64.8 54.6 36.8 39.5 42.0 79.4 74.3 54.1 147.7 47.3 53.1 70.8 29.4 78.7 13.1 109.3 142.4 57.5 97.8 98.0 42.4 67.6 102.6 59.5 49.1 44.6 29.6 51.2 50.1 71.7 62.4 137.2 42.2 92.8 116.7 334.5 117.9 44.6 111.3 75.2 56.2 91.0 43.6 130.1 91.4 118.7 67.7 53.8 71.5 33.8 67.9 75.0 98.0 146.2 85.4 114.0 86.2 145.3 101.7 64.1 109.4 75.3 100.6 47.6 44.4 100.7 44.7 45.5 30.6 39.6 40.3 46.8 45.4 41.3 38.1 36.6 65.7 53.7 55.2 59.1 43.0 39.6 97.6 113.2 118.5 131.4 91.7 102.0 130.9 121.8 127.7 108.1 120.4 127.3 74.0 19.2 25.7 21.2 68.3 62.1 86.2 115.1 75.7 60.1 85.0 79.8 18.1 71.4 59.5 95.6 14.6 152.2 52.4 148.4 127.2 93.8 44.3 58.2 43.2 70.7 114.7 63.1 15.1 94.9 166.7 71.3 99.4 51.0 29.9 56.5 76.1 62.2 109.6 67.3 18.7 112.4 118.0 62.8 52.7 38.0 86.3 62.6 71.2 15.9 76.9 104.1 59.8 8.5 41.3 82.3 154.7 76.3 78.0 81.1 135.5 113.9 59.3 36.0 92.1 50.1 121.0 64.5 38.7 69.8 69.3 209.9 63.3 46.4 92.8 104.6 RAB18 ENSG00000099246 "RAB18, member RAS oncogene family" Q9NP72 10 27504174-27542239 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Protein transport, Transport" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025928 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 30: Mammary glandular cells - Lactation" "HPA025928: AB_1855997" "unprognostic (9.45e-3)" "unprognostic (7.71e-2)" "unprognostic (2.95e-1)" "unprognostic (6.71e-2)" "unprognostic (3.37e-2)" "unprognostic (1.28e-2)" "unprognostic (8.59e-3)" "unprognostic (1.17e-1)" "unprognostic (3.64e-1)" "unprognostic (1.27e-2)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (1.71e-3)" "unprognostic (9.55e-2)" "unprognostic (1.01e-1)" "unprognostic (1.39e-1)" "unprognostic (8.48e-2)" 40.8 55.5 26.3 29.0 26.8 88.9 50.7 28.9 32.1 32.3 26.5 34.3 33.5 30.5 41.0 44.5 25.4 26.7 48.0 26.4 33.4 47.5 52.3 30.0 26.2 28.5 30.2 30.8 31.5 53.2 20.4 36.7 31.8 41.2 35.2 70.6 28.0 34.1 51.2 35.7 30.9 37.4 30.9 30.0 32.0 34.3 30.1 34.9 41.1 50.5 32.9 39.7 31.0 33.5 68.1 47.5 56.8 41.0 94.1 53.3 37.9 102.6 47.0 87.6 83.4 46.2 44.6 27.7 42.7 88.8 44.2 44.9 37.4 65.6 72.0 42.3 34.1 39.2 44.2 59.3 68.0 16.9 45.4 70.5 122.2 55.0 31.4 62.3 68.5 25.7 22.6 55.2 75.0 44.1 37.8 11.6 24.8 38.7 22.1 27.3 93.8 33.7 83.5 37.6 30.5 36.9 50.6 57.1 67.5 59.6 115.6 35.0 68.5 40.0 49.9 76.8 60.1 24.0 47.5 34.7 68.6 97.6 22.6 212.9 54.4 137.4 41.7 50.7 91.5 25.6 35.7 45.1 40.6 26.5 30.1 35.9 193.2 45.2 60.9 26.7 42.7 49.8 26.3 26.8 28.9 32.1 26.4 33.4 28.5 30.2 31.8 30.9 30.1 33.5 50.3 73.7 44.5 37.5 51.4 186.0 105.3 145.9 68.9 74.1 131.7 51.2 131.4 48.6 92.9 90.1 41.7 90.5 64.9 82.3 213.2 105.0 46.7 46.7 55.4 62.1 65.4 41.2 53.9 90.4 114.9 78.7 31.6 51.8 34.9 63.6 62.8 85.1 84.5 48.8 51.2 47.5 152.5 81.0 83.4 33.8 63.0 62.4 99.6 42.2 115.6 117.6 53.5 43.7 54.8 120.5 57.8 69.2 51.3 127.6 73.1 208.6 72.8 91.0 26.3 45.9 76.9 138.7 81.0 80.7 199.0 149.1 60.9 79.1 40.9 132.6 RAB23 ENSG00000112210 "RAB23, member RAS oncogene family" Q9ULC3 6 57186992-57222307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 22.3;Peritubular cells: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC TERT1: 97.2;U-2197: 177.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029135, HPA029136" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA029135: AB_10602070, HPA029136: AB_10601794" "unprognostic (8.78e-2)" "unprognostic (6.55e-2)" "unprognostic (7.17e-2)" "unprognostic (1.10e-1)" "unprognostic (2.14e-2)" "unprognostic (2.28e-2)" "unprognostic (2.55e-2)" "unprognostic (5.33e-3)" "unprognostic (6.41e-2)" "unprognostic (6.55e-2)" "unprognostic (1.05e-1)" "unprognostic (2.97e-2)" "unprognostic (9.12e-3)" "unprognostic (1.36e-2)" "unprognostic (2.38e-1)" "unprognostic (6.37e-2)" "unprognostic (1.46e-3)" 9.6 6.1 8.6 13.2 9.0 0.8 7.8 10.9 9.6 45.9 6.1 59.7 7.0 52.6 14.1 19.9 14.5 26.9 12.3 8.5 15.2 7.3 4.1 10.6 4.5 8.7 8.7 10.8 2.9 5.7 3.4 27.6 9.5 38.7 15.9 3.9 3.9 55.7 6.1 4.8 10.8 75.0 9.2 2.2 11.6 5.1 9.7 3.2 32.6 10.4 4.1 46.7 14.7 11.5 15.6 6.1 21.6 15.3 32.3 97.2 19.8 44.9 77.4 38.6 39.7 13.4 7.3 3.1 13.6 72.3 19.3 5.5 22.7 16.4 45.6 11.6 10.5 11.3 9.4 10.6 19.8 5.9 1.6 36.5 18.6 48.1 44.7 18.7 20.3 6.6 17.6 9.3 43.4 13.2 5.2 6.3 8.1 10.3 8.2 5.7 31.7 4.7 26.8 10.7 11.2 7.6 22.5 10.6 11.6 26.8 9.7 6.8 27.4 59.6 18.5 177.4 26.6 8.0 9.3 7.6 33.5 12.5 30.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.2 0.0 0.0 8.6 9.0 10.9 9.6 8.5 15.2 8.7 8.7 9.5 9.2 9.7 11.5 2.9 12.8 5.0 6.8 0.7 4.1 1.6 2.0 5.7 2.5 4.0 3.0 3.4 1.5 1.6 0.0 2.1 11.5 1.7 2.4 0.0 3.4 2.4 6.5 15.5 2.6 1.2 4.8 13.0 2.9 10.7 22.3 1.1 6.2 0.0 3.7 4.6 3.4 4.2 1.7 12.3 1.4 2.0 0.8 3.1 2.5 19.9 1.4 5.4 11.2 7.7 4.4 0.0 8.0 5.3 2.6 0.1 30.5 0.5 3.5 0.6 6.1 5.3 0.9 0.0 17.2 14.5 6.6 7.8 4.1 5.1 13.7 0.8 4.0 1.6 1.8 RAB33B DKFZP434G099 ENSG00000172007 "RAB33B, member RAS oncogene family" Q9H082 4 139453232-139476609 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 72.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 22.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048367 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA048367: AB_2680372" "unprognostic (2.11e-1)" "unprognostic (1.19e-1)" "unprognostic (4.87e-2)" "unprognostic (1.12e-1)" "unprognostic (3.11e-1)" "unprognostic (2.09e-1)" "unprognostic (3.18e-1)" "unprognostic (4.50e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-2)" "unprognostic (9.45e-2)" "unprognostic (2.36e-2)" "unprognostic (4.37e-3)" "unprognostic (1.48e-1)" "unprognostic (2.59e-1)" "unprognostic (8.06e-3)" "prognostic favorable (9.19e-4)" 8.4 5.2 3.7 5.2 4.4 12.8 7.1 7.0 5.3 8.1 2.2 4.1 3.8 9.5 4.2 6.6 5.6 6.0 6.5 3.3 4.4 5.0 16.7 6.8 6.5 5.5 4.5 9.9 10.0 4.1 2.8 9.0 5.8 6.8 4.1 4.1 4.2 5.6 4.2 4.9 4.2 8.4 4.6 7.5 5.4 3.6 4.8 5.4 6.3 5.2 5.8 5.6 3.1 7.4 5.1 1.9 5.6 7.7 12.6 12.3 9.4 6.1 8.5 5.2 6.4 5.5 8.0 10.7 3.0 7.0 2.6 4.8 6.1 5.4 6.2 10.1 4.0 3.7 4.5 6.4 12.6 6.8 8.4 9.5 5.9 6.6 6.2 9.4 15.3 6.7 4.1 20.6 3.9 3.5 5.8 6.0 3.9 8.5 3.2 7.3 8.4 4.7 7.3 3.4 7.4 7.6 4.3 8.5 10.1 6.2 3.9 4.7 10.7 6.2 4.5 10.6 3.4 10.9 13.3 6.9 6.2 7.3 5.6 4.3 3.4 8.7 3.6 3.5 5.8 4.3 4.5 4.0 2.3 3.6 5.6 5.1 22.6 4.3 3.4 2.8 5.2 3.5 3.7 4.4 7.0 5.3 3.3 4.4 5.5 4.5 5.8 4.6 4.8 7.4 13.9 6.4 7.7 5.2 15.1 9.9 7.2 3.4 18.2 5.0 10.0 6.3 10.1 5.7 4.1 3.7 0.0 6.3 9.1 5.3 1.9 5.3 34.1 13.7 11.3 12.0 8.4 3.8 5.9 4.7 5.7 10.7 7.1 10.6 6.3 3.3 11.4 19.7 6.6 3.3 7.5 8.2 2.0 9.4 8.9 72.1 10.5 7.1 1.8 10.3 8.6 5.9 3.1 10.1 8.9 6.2 5.2 12.8 10.9 6.8 6.3 4.5 6.4 8.5 6.6 12.8 9.9 4.6 4.3 12.9 11.6 16.8 13.2 3.4 6.5 5.9 RAB3GAP1 "KIAA0066, RAB3GAP, RAB3GAP130, WARBM1" ENSG00000115839 "RAB3 GTPase activating protein catalytic subunit 1" Q15042 2 135052292-135176394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034494, HPA034495" Approved Approved Nucleoplasm,Cytosol NA NA 6300 "Cluster 41: Basophils - Cellular respiration" "Cluster 52: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "HPA034494: AB_2674188, HPA034495: AB_10670158" "unprognostic (1.02e-2)" "unprognostic (2.43e-2)" "unprognostic (5.73e-2)" "prognostic unfavorable (2.96e-4)" "unprognostic (2.18e-1)" "unprognostic (9.57e-2)" "unprognostic (2.96e-2)" "unprognostic (7.00e-2)" "unprognostic (3.18e-1)" "unprognostic (1.13e-2)" "unprognostic (3.15e-2)" "unprognostic (2.05e-1)" "unprognostic (8.40e-3)" "unprognostic (2.41e-2)" "unprognostic (3.75e-1)" "unprognostic (4.11e-1)" "unprognostic (2.15e-1)" 23.4 21.1 22.5 24.3 24.1 37.5 25.6 18.7 23.1 27.5 22.0 23.7 19.1 29.2 30.6 26.2 22.9 21.6 35.2 24.5 24.1 23.2 20.5 20.4 25.9 23.3 23.2 35.2 35.4 34.0 18.9 23.6 24.3 29.5 27.9 34.1 35.6 28.3 36.9 26.2 21.4 30.9 19.7 21.3 26.1 18.7 23.1 30.3 30.8 36.0 30.4 26.0 22.4 22.0 51.2 20.4 34.8 29.0 67.3 57.0 32.4 76.6 62.6 59.5 58.4 45.3 40.7 75.5 46.2 78.5 22.8 42.2 37.4 70.6 72.1 36.2 37.9 34.3 24.8 39.9 46.9 46.8 39.3 50.2 91.2 54.8 98.2 53.6 43.6 33.7 49.5 42.5 54.7 30.1 24.1 18.2 27.1 30.7 33.8 40.9 45.0 31.9 35.0 44.9 28.3 22.4 52.0 30.7 36.8 30.5 27.2 33.6 53.0 60.0 45.7 26.0 32.5 30.1 18.2 55.8 39.2 27.8 34.3 10.3 4.3 6.7 1.5 5.3 1.3 5.5 3.8 2.1 4.5 6.8 7.9 4.2 1.7 3.1 6.0 2.3 5.4 2.1 22.5 24.1 18.7 23.1 24.5 24.1 23.3 23.2 24.3 19.7 23.1 22.0 34.3 25.6 26.7 86.8 50.4 30.2 46.8 28.8 27.9 28.9 30.2 27.8 58.0 32.9 32.6 31.3 50.1 23.6 15.3 39.4 11.7 20.0 34.8 31.8 33.0 28.5 34.6 24.4 137.8 26.9 17.1 35.5 46.9 31.5 46.3 27.2 32.9 25.7 22.4 30.3 106.8 31.2 28.5 26.7 28.1 23.2 30.7 32.4 23.2 112.4 24.2 18.0 6.2 107.1 123.3 34.6 24.3 35.7 40.0 42.5 29.9 21.1 36.0 33.8 46.0 31.8 34.4 41.8 25.8 37.5 29.7 39.1 28.3 35.0 24.7 51.0 RAB3GAP2 "DKFZP434D245, KIAA0839, RAB3-GAP150, SPG69" ENSG00000118873 "RAB3 GTPase activating non-catalytic protein subunit 2" Q9H2M9 1 220148293-220272453 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Cataract, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026273, HPA027299" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane" "HPA026273: AB_1856007, HPA027299: AB_1856008" "prognostic unfavorable (3.05e-4)" "unprognostic (2.80e-3)" "unprognostic (1.76e-2)" "unprognostic (6.07e-2)" "unprognostic (5.20e-2)" "unprognostic (1.69e-1)" "unprognostic (2.40e-2)" "unprognostic (7.00e-2)" "unprognostic (4.61e-2)" "unprognostic (1.75e-1)" "unprognostic (4.63e-2)" "unprognostic (2.13e-1)" "unprognostic (7.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.17e-1)" "unprognostic (3.99e-2)" "unprognostic (1.56e-1)" 10.1 9.0 6.3 9.6 6.7 10.2 11.2 11.4 7.8 8.7 23.5 8.8 7.8 9.4 8.4 9.0 7.0 7.9 9.3 7.3 9.3 11.7 10.0 8.6 12.6 6.7 6.9 9.6 8.6 18.6 6.2 11.5 9.0 8.5 8.3 18.1 9.2 7.9 8.7 7.9 7.8 9.3 5.7 9.2 9.4 6.6 7.5 13.1 12.8 12.2 14.4 9.1 6.0 9.1 21.3 15.8 18.9 14.3 21.2 25.1 21.4 21.4 20.3 18.9 22.2 14.7 17.3 26.4 14.8 20.9 14.3 19.9 19.8 16.4 21.8 22.1 12.9 20.6 21.5 13.8 27.9 29.8 20.3 20.0 18.4 18.5 28.5 21.2 17.6 11.4 36.2 16.6 21.6 6.0 23.0 10.5 40.8 11.4 9.3 12.5 26.0 23.7 16.1 17.3 18.8 22.7 22.2 21.4 35.3 20.3 22.4 28.0 25.7 20.6 9.6 14.4 23.2 14.6 19.2 22.8 17.7 24.6 24.8 10.0 2.8 5.6 4.8 3.6 5.9 4.8 4.7 6.2 3.8 3.8 4.1 4.9 1.8 2.8 3.9 2.4 6.0 3.3 6.3 6.7 11.4 7.8 7.3 9.3 6.7 6.9 9.0 5.7 7.5 9.1 28.5 41.7 21.9 60.7 30.4 11.6 13.6 15.8 17.6 57.9 18.9 16.3 34.8 32.9 23.4 25.8 68.8 18.5 30.6 23.8 5.9 17.4 4.3 21.4 27.7 22.3 35.4 18.7 106.8 16.7 13.5 23.4 20.4 28.5 19.6 40.8 28.9 24.2 25.4 42.1 105.1 22.1 16.2 29.0 9.4 2.8 18.0 22.2 14.2 68.4 25.2 39.8 26.8 82.0 81.5 21.7 14.2 25.9 24.7 21.0 19.4 14.9 17.2 50.5 6.6 24.1 20.4 17.7 13.6 17.5 9.8 23.1 27.1 23.6 19.3 13.2 RAC3 ENSG00000169750 "Rac family small GTPase 3" P60763 17 82031678-82034204 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 45.0;Extravillous trophoblasts: 152.1;Spermatogonia: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "CACO-2: 230.8;HEK 293: 274.7;NB-4: 156.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047820 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA047820: AB_2680167" "unprognostic (3.48e-2)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (6.21e-5)" "unprognostic (1.62e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-2)" "unprognostic (3.36e-2)" "unprognostic (1.57e-1)" "unprognostic (6.62e-2)" "unprognostic (1.22e-2)" "unprognostic (3.67e-1)" "unprognostic (4.39e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.25e-3)" 12.3 5.0 22.8 1.8 20.8 7.7 13.7 26.3 29.5 5.3 9.3 4.8 3.4 2.8 7.3 10.9 3.8 3.0 3.0 19.7 24.5 9.4 20.7 4.0 1.7 23.3 22.3 4.8 4.7 9.3 22.8 5.6 27.0 11.1 1.4 2.8 18.1 4.2 0.8 12.4 3.7 1.3 15.3 1.9 11.8 28.1 26.5 2.2 9.8 0.2 1.5 3.1 7.6 20.6 11.1 15.1 45.6 63.1 9.7 18.2 50.5 7.8 7.2 26.1 22.3 230.8 21.4 5.8 11.5 4.8 1.7 15.6 43.0 17.8 4.1 3.6 274.7 64.6 20.2 16.7 47.0 28.0 12.2 27.5 13.0 3.5 12.0 19.5 60.3 33.8 103.1 30.2 10.8 35.6 7.3 156.4 61.4 39.2 27.6 47.6 4.5 27.7 20.0 5.4 109.8 111.5 4.1 57.2 55.7 16.1 58.6 40.7 21.6 10.8 9.8 5.5 12.1 14.6 9.9 4.4 6.6 17.3 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 22.8 20.8 26.3 29.5 19.7 24.5 23.3 22.3 27.0 15.3 26.5 20.6 1.6 0.0 0.0 2.3 0.9 8.7 16.3 12.2 19.9 5.3 36.9 45.0 0.2 4.3 3.6 5.5 0.0 30.0 1.8 3.3 21.5 9.8 19.1 5.9 5.4 2.3 3.0 6.9 5.2 3.3 152.1 10.7 8.2 12.6 4.5 17.8 1.4 11.3 9.7 6.7 8.3 5.1 22.4 0.0 2.6 16.6 5.6 0.9 14.2 0.0 2.0 6.0 0.0 3.5 2.0 5.5 2.4 1.9 2.6 16.4 4.2 26.0 2.4 7.3 0.0 0.8 5.3 2.2 58.0 15.8 7.5 14.1 3.1 8.6 5.2 8.4 RAD21 "hHR21, KIAA0078, SCC1" ENSG00000164754 "RAD21 cohesin complex component" O60216 8 116845934-116874776 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Activator, Developmental protein, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 424.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020044, CAB022065, HPA073277" Supported Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "CAB022065: , HPA020044: AB_1856035, HPA073277: " "unprognostic (7.85e-2)" "unprognostic (4.92e-1)" "unprognostic (3.05e-1)" "unprognostic (5.43e-3)" "unprognostic (9.56e-2)" "unprognostic (3.50e-1)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.86e-3)" "unprognostic (8.99e-2)" "unprognostic (8.80e-2)" "unprognostic (5.58e-3)" "unprognostic (3.56e-2)" "unprognostic (4.40e-2)" "unprognostic (2.00e-1)" "unprognostic (1.82e-1)" "unprognostic (1.39e-1)" "unprognostic (1.95e-1)" 75.4 80.5 62.9 74.0 74.5 206.0 71.9 74.7 75.7 50.5 56.7 73.1 57.3 67.6 54.6 71.2 50.6 49.4 89.8 58.1 74.3 68.2 64.7 67.9 122.8 70.0 69.3 67.8 41.9 82.3 33.8 90.1 75.2 57.5 82.5 114.2 56.9 65.0 76.6 54.0 60.4 60.2 71.9 75.5 56.4 88.7 67.2 177.2 80.9 95.5 119.5 59.7 44.5 97.1 301.6 143.9 277.3 156.7 136.5 117.0 124.2 202.1 191.4 220.8 202.4 119.8 275.2 438.6 109.4 146.0 117.4 162.4 238.5 132.1 257.6 589.1 153.1 447.6 167.2 153.7 85.5 145.7 253.1 100.2 106.0 129.4 156.0 146.1 176.4 625.8 183.6 595.6 193.1 181.1 665.4 86.2 163.6 385.4 179.2 241.8 201.5 223.4 133.5 173.3 348.2 179.1 212.2 569.4 140.6 144.5 238.3 178.5 128.5 154.6 223.5 164.4 217.1 313.3 383.9 391.9 132.8 206.7 189.7 35.3 7.9 28.0 17.4 8.7 17.5 14.4 20.3 20.6 9.0 12.8 20.8 20.6 29.7 14.3 12.7 7.6 43.7 11.4 62.9 74.5 74.7 75.7 58.1 74.3 70.0 69.3 75.2 71.9 67.2 97.1 115.7 256.4 157.1 24.5 111.2 95.6 77.5 62.5 78.0 75.4 65.8 53.0 155.2 51.5 101.0 55.2 31.3 142.4 118.1 90.4 43.0 54.0 258.0 67.0 86.7 97.0 84.4 249.8 39.3 44.9 157.0 89.4 57.1 88.2 153.5 112.9 75.0 72.1 67.9 67.3 48.1 72.7 69.2 93.1 100.0 424.9 116.5 93.4 69.4 45.9 110.8 112.5 77.2 41.2 58.3 63.5 66.3 106.5 124.0 100.0 35.7 59.4 70.5 67.9 72.3 88.6 85.3 33.2 88.6 103.7 100.4 113.7 134.1 85.5 94.1 95.5 RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12583601-12664125 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 175.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 175.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002639, HPA002640, CAB019291" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "CAB019291: , HPA002639: , HPA002640: AB_1856047" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (5.92e-2)" "unprognostic (2.17e-3)" "unprognostic (6.51e-3)" "unprognostic (7.66e-3)" "unprognostic (2.66e-3)" "unprognostic (1.53e-2)" "unprognostic (2.72e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" 42.4 34.2 36.7 33.8 37.9 77.4 39.2 42.6 37.4 47.6 40.4 46.8 40.5 45.6 34.0 55.5 43.2 31.0 89.6 36.9 35.8 46.7 68.9 44.7 36.3 38.3 36.9 52.0 50.6 63.6 28.3 39.1 37.0 41.9 42.0 37.4 39.6 38.0 194.9 56.0 43.4 45.5 36.7 48.3 55.5 26.8 38.1 52.8 48.8 122.5 47.7 46.1 46.2 39.8 49.9 57.9 85.5 66.6 74.3 59.6 168.0 73.9 129.1 100.1 112.5 46.6 41.3 52.7 34.6 120.1 51.6 31.9 93.4 67.5 103.8 91.4 70.2 72.0 69.4 42.9 74.2 70.1 64.7 55.3 67.8 102.3 82.0 67.6 73.1 78.2 52.6 136.0 98.3 88.6 91.1 47.8 86.5 64.0 76.4 72.6 75.7 66.4 60.9 76.9 26.1 56.2 61.1 59.8 40.9 66.1 99.1 91.5 51.1 65.6 62.5 55.7 85.0 103.3 178.4 112.3 57.2 80.4 73.9 40.4 32.7 62.5 22.3 32.6 22.5 19.5 21.9 22.3 30.3 20.4 21.9 22.8 175.1 29.8 34.2 13.5 28.3 28.2 36.7 37.9 42.6 37.4 36.9 35.8 38.3 36.9 37.0 36.7 38.1 39.8 28.5 22.4 37.6 47.7 36.1 34.4 35.2 22.1 27.9 56.7 27.5 22.6 29.0 35.8 25.7 27.6 66.7 40.0 41.5 31.3 13.7 25.6 8.8 33.2 37.1 32.7 29.3 46.7 46.1 37.0 46.8 32.3 27.5 43.8 34.2 78.7 36.0 41.2 28.6 43.7 52.9 31.0 30.5 39.3 43.4 4.6 39.1 34.7 26.6 44.0 49.5 31.9 51.5 65.4 64.0 35.5 29.9 41.3 43.3 46.9 47.3 20.1 31.2 81.9 32.9 56.2 39.1 28.3 33.6 31.8 43.5 62.3 40.8 35.6 31.2 47.1 RAPSN "CMS1D, CMS1E, RNF205" ENSG00000165917 "Receptor associated protein of the synapse" Q13702 11 47437764-47449143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 88.9;tongue: 33.1" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 63.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RH-30: 238.7" "Low region specificity" "Detected in some" HPA039475 Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Centrosome, Cytosol" "HPA039475: AB_10794196" "unprognostic (5.37e-2)" "unprognostic (1.02e-1)" "unprognostic (7.34e-2)" "unprognostic (4.58e-2)" "unprognostic (2.95e-2)" "unprognostic (1.44e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-3)" "unprognostic (1.35e-1)" "unprognostic (5.38e-2)" "unprognostic (4.81e-2)" "unprognostic (2.89e-2)" "unprognostic (1.08e-2)" "unprognostic (1.64e-4)" "unprognostic (3.83e-1)" "unprognostic (4.73e-3)" "unprognostic (4.48e-2)" 0.3 1.5 0.5 0.2 0.5 0.3 0.2 0.3 1.2 0.2 0.9 0.8 0.1 0.0 0.1 1.2 0.1 0.1 2.6 0.5 0.5 0.3 0.5 0.4 0.2 0.3 0.5 0.0 0.2 0.0 0.1 2.1 0.5 0.7 0.0 0.1 1.3 0.0 88.9 0.5 0.5 0.1 0.4 0.6 0.2 0.3 0.6 0.1 0.2 33.1 0.1 0.1 0.1 0.5 0.0 0.2 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.2 0.7 0.1 0.2 1.2 4.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 59.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 238.7 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.3 0.1 0.3 0.3 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 1.2 0.5 0.5 0.3 0.5 0.5 0.4 0.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.3 1.4 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.5 2.7 0.3 0.1 0.2 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.5 0.0 0.2 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.3 0.3 13.8 0.0 0.5 0.0 0.0 0.6 1.3 0.0 0.5 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 1.1 0.0 0.0 63.8 0.5 0.0 0.4 0.0 0.0 0.3 0.4 0.1 0.2 0.1 RARB "HAP, NR1B2, RRB2" ENSG00000077092 "Retinoic acid receptor beta" P10826 3 25174332-25597932 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Microphthalmia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 41.4;Excitatory neurons: 66.8;Inhibitory neurons: 92.6;Microglial cells: 29.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 13.7;HEK 293: 16.0;hTERT-RPE1: 82.3;WM-115: 36.5" "Region enriched" "Detected in all" 9 "basal ganglia: 109.2" "CAB002617, HPA004174" Enhanced Enhanced Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB002617: , HPA004174: AB_1079744" "unprognostic (2.04e-2)" "unprognostic (3.53e-2)" "unprognostic (1.93e-1)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (6.72e-2)" "unprognostic (1.30e-2)" "unprognostic (2.70e-2)" "unprognostic (2.43e-1)" "unprognostic (4.71e-2)" "unprognostic (1.62e-1)" "unprognostic (2.86e-1)" "prognostic favorable (3.43e-5)" "unprognostic (9.24e-3)" "unprognostic (2.28e-1)" "unprognostic (9.99e-2)" "unprognostic (6.56e-3)" 4.1 7.0 3.5 2.6 15.0 0.0 6.9 2.2 6.6 9.3 7.2 6.0 1.7 7.4 6.7 7.9 6.0 5.3 14.0 3.5 1.4 15.1 6.5 5.3 6.7 3.4 1.7 11.5 1.3 6.0 7.5 14.4 0.9 12.5 2.2 13.6 13.1 11.2 2.4 1.1 2.0 5.9 1.4 4.9 3.9 0.6 2.4 1.2 9.1 5.3 4.2 7.2 6.1 3.7 0.0 1.9 1.2 6.4 13.7 3.6 0.0 1.6 0.8 0.0 0.6 0.3 0.1 0.1 0.2 2.5 0.3 0.4 0.0 0.3 0.0 0.1 16.0 0.1 0.1 1.1 0.3 0.2 0.1 7.1 0.0 0.0 0.0 82.3 13.4 0.1 0.1 5.6 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.6 8.3 0.0 0.2 0.1 9.1 0.0 0.1 0.0 1.1 0.1 2.1 7.0 0.2 0.0 0.1 5.6 0.2 36.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 15.0 2.2 6.6 3.5 1.4 3.4 1.7 0.9 1.4 2.4 3.7 2.4 0.0 0.5 41.4 0.3 0.1 18.0 6.4 1.8 4.5 1.7 7.5 12.0 12.8 14.9 11.0 25.0 0.2 0.8 0.0 0.0 1.6 1.5 8.3 4.2 10.5 0.0 0.0 66.8 0.9 0.1 6.8 7.7 3.0 0.0 0.1 22.1 2.1 0.4 5.0 92.6 0.0 2.0 1.9 0.4 1.2 0.0 0.3 0.0 29.0 0.0 24.8 0.0 19.6 2.9 1.4 0.0 0.0 0.2 10.2 0.6 0.6 9.2 6.3 0.0 2.9 9.7 0.2 1.0 6.6 0.1 0.3 0.5 0.2 0.2 9.7 RARS2 "DALRD2, dJ382I10.6, MGC14993, MGC23778, PRO1992, RARSL" ENSG00000146282 "Arginyl-tRNA synthetase 2, mitochondrial" Q5T160 6 87513938-87589987 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039987, HPA042645" Uncertain Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA039987: AB_2676786, HPA042645: AB_2678097" "unprognostic (1.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-2)" "unprognostic (6.98e-2)" "unprognostic (9.27e-2)" "unprognostic (5.41e-2)" "unprognostic (6.61e-2)" "unprognostic (4.30e-2)" "unprognostic (1.88e-1)" "unprognostic (1.08e-3)" "unprognostic (8.28e-2)" "unprognostic (2.20e-1)" "unprognostic (7.56e-3)" "unprognostic (1.62e-1)" "unprognostic (1.89e-2)" "unprognostic (5.73e-2)" "unprognostic (7.16e-3)" 24.0 39.6 10.8 15.8 11.8 19.3 21.3 14.7 11.6 21.5 19.2 20.8 17.8 21.8 18.6 17.7 19.7 19.0 22.7 10.4 11.4 20.5 27.9 18.3 16.8 11.5 11.6 18.5 24.0 21.4 17.5 22.2 11.8 18.8 22.7 25.9 20.8 13.6 22.5 18.5 22.6 21.5 11.0 18.5 19.2 25.3 12.5 18.5 20.6 19.3 19.0 20.6 18.2 15.5 19.8 19.1 45.1 49.8 44.6 47.5 31.9 46.6 54.2 30.8 38.6 36.6 21.6 25.0 26.9 47.4 32.0 26.7 37.9 25.8 43.2 18.0 36.0 25.7 24.4 58.7 56.1 30.7 21.3 48.9 24.6 26.4 33.1 44.5 41.0 25.7 59.6 24.4 46.8 35.2 10.0 32.8 29.2 42.3 20.0 19.9 45.9 22.2 38.5 40.1 40.8 54.7 24.8 12.1 33.1 38.2 22.5 45.8 28.1 21.2 16.8 22.8 38.4 25.6 45.1 21.1 32.2 31.8 36.6 18.8 17.8 22.7 16.1 18.6 19.0 15.1 20.4 15.1 15.6 16.2 19.9 16.9 11.9 18.6 20.7 17.9 27.9 15.4 10.8 11.8 14.7 11.6 10.4 11.4 11.5 11.6 11.8 11.0 12.5 15.5 34.4 19.2 15.6 30.0 21.2 17.3 35.4 51.3 12.5 13.9 17.3 16.8 19.9 10.0 37.8 11.0 20.9 31.0 18.1 14.6 45.0 32.9 95.3 23.5 29.3 22.8 9.0 7.4 46.8 46.9 45.5 28.3 12.8 20.3 18.3 27.9 23.6 15.5 20.5 6.7 59.0 23.5 44.7 13.5 14.1 50.6 25.4 15.0 19.6 38.4 22.6 13.6 19.6 56.3 63.9 37.6 21.2 24.0 20.7 30.8 57.2 32.9 24.2 20.3 26.3 18.9 30.0 61.8 33.7 14.1 18.0 39.5 20.6 51.4 27.0 33.9 RASA1 "CM-AVM, GAP, p120, p120GAP, p120RASGAP, RASA" ENSG00000145715 "RAS p21 protein activator 1" P20936 5 87267883-87391931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 96.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 196.7;Excitatory neurons: 192.1;Inhibitory neurons: 234.7;Oligodendrocyte precursor cells: 165.4;Oligodendrocytes: 220.1;Syncytiotrophoblasts: 487.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007789, HPA036393, HPA064556" Enhanced NA NA 12000 "Cluster 15: NK-cells - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB007789: AB_598183, HPA036393: AB_2675097, HPA064556: AB_2685285" "unprognostic (1.57e-1)" "unprognostic (7.63e-2)" "unprognostic (1.88e-3)" "unprognostic (2.14e-1)" "unprognostic (1.23e-1)" "unprognostic (1.38e-2)" "unprognostic (6.88e-2)" "unprognostic (8.38e-3)" "unprognostic (2.23e-1)" "unprognostic (1.07e-2)" "unprognostic (4.12e-3)" "unprognostic (1.03e-1)" "unprognostic (3.98e-2)" "unprognostic (1.59e-2)" "unprognostic (5.39e-2)" "unprognostic (1.65e-1)" "unprognostic (1.30e-3)" 16.4 14.6 12.3 15.1 14.5 13.9 18.6 21.8 15.6 17.4 9.9 14.7 12.4 21.1 20.3 16.7 15.6 16.2 12.9 15.6 12.5 15.2 12.4 15.0 19.7 9.6 13.2 25.8 13.3 24.8 11.5 96.8 12.7 14.1 17.5 34.6 15.4 15.3 9.5 18.6 13.8 15.5 9.5 19.1 13.7 26.7 11.2 25.3 24.4 15.7 18.1 17.0 12.6 15.5 31.7 16.1 31.0 20.6 26.5 37.3 23.5 47.5 32.0 30.3 49.2 13.0 82.9 20.7 11.1 54.9 33.8 15.4 14.0 40.7 95.0 19.9 11.1 15.6 15.3 13.7 25.3 12.7 18.6 21.0 27.1 84.1 48.5 51.5 42.5 11.8 8.8 44.4 109.3 20.5 14.7 21.8 16.6 6.9 29.5 17.5 66.4 30.0 29.0 27.7 18.2 20.1 18.4 24.4 29.6 29.4 21.7 20.4 61.3 38.3 17.6 21.1 60.0 16.0 15.6 20.5 55.1 25.3 27.3 2.1 0.6 0.9 0.9 1.2 1.6 0.7 1.2 1.0 0.5 1.1 1.0 0.9 0.8 3.9 1.2 0.6 1.8 0.5 12.3 14.5 21.8 15.6 15.6 12.5 9.6 13.2 12.7 9.5 11.2 15.5 18.6 12.8 15.8 86.5 13.9 14.9 6.7 12.5 16.5 35.7 18.5 11.4 6.4 7.2 15.2 16.5 29.2 196.7 11.5 12.5 5.9 10.4 7.7 15.7 18.3 20.2 16.2 12.8 192.1 7.8 53.7 16.2 18.3 16.5 8.8 22.1 18.2 11.7 47.8 32.0 234.7 12.9 12.2 27.1 9.5 4.8 14.0 21.2 14.2 128.4 13.6 12.6 7.2 165.4 220.1 23.4 14.8 13.5 15.9 11.9 10.7 11.2 19.1 18.6 0.0 21.6 15.0 33.9 20.0 17.7 17.5 487.5 17.7 16.4 13.8 11.2 RAX RX ENSG00000134438 "Retina and anterior neural fold homeobox" Q9Y2V3 18 59267035-59274086 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "pituitary gland: 6.6;retina: 16.0" "Cell type enriched" "Detected in some" 5 "Muller glia cells: 493.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "white matter: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.8;SH-SY5Y: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 77: Retina - Visual perception" "Cluster 3: HMC-1 - Innate immune response" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (4.14e-2)" "unprognostic (1.79e-1)" "unprognostic (3.76e-3)" "unprognostic (2.28e-1)" "unprognostic (2.22e-1)" "unprognostic (1.33e-1)" "unprognostic (3.46e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 6.6 0.0 0.0 0.1 0.0 16.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 83.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 493.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 20.7 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RBBP8 "COM1, CtIP, RIM, SCKL2" ENSG00000101773 "RB binding protein 8, endonuclease" Q99708 18 22798261-23026488 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 125.9;Spermatocytes: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 36.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039890, HPA052946" Approved Supported Nucleoplasm NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA039890: AB_10794756, HPA052946: AB_2681996" "unprognostic (1.55e-3)" "unprognostic (4.10e-3)" "unprognostic (7.89e-2)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (7.28e-2)" "unprognostic (3.60e-3)" "unprognostic (1.87e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (2.29e-2)" "unprognostic (1.58e-3)" "unprognostic (1.04e-2)" "prognostic favorable (1.71e-5)" "unprognostic (3.91e-3)" "unprognostic (2.42e-2)" "unprognostic (1.01e-2)" "unprognostic (4.48e-1)" 10.1 8.7 6.8 10.0 6.8 18.2 29.4 9.2 11.3 20.9 41.6 14.5 9.3 20.1 23.4 22.1 28.0 12.7 7.0 7.4 9.2 42.2 14.4 13.5 14.0 6.3 7.3 6.4 18.5 22.1 17.5 8.5 6.4 10.8 12.9 6.2 19.5 23.3 2.3 28.5 12.9 16.4 6.2 7.6 13.1 28.7 8.5 32.4 18.2 3.5 17.3 18.3 18.0 7.3 32.9 24.8 36.0 41.9 18.2 19.4 28.2 44.2 31.1 40.3 56.5 45.7 36.3 95.4 19.9 27.9 38.5 67.3 41.2 89.9 78.5 68.3 33.2 41.8 32.0 44.0 22.2 151.5 43.7 13.9 86.0 61.0 105.3 23.6 16.6 65.7 25.0 69.2 41.6 49.1 112.8 50.6 34.2 60.1 41.5 57.6 65.9 58.9 117.4 34.7 84.1 39.8 74.1 22.4 39.0 20.5 129.1 39.4 12.0 107.2 49.3 52.4 78.0 92.9 108.4 105.3 49.1 72.2 58.8 17.0 6.5 3.9 1.2 24.0 0.5 6.6 1.7 2.1 8.2 5.3 0.9 1.5 2.4 7.9 36.7 8.1 4.7 3.8 6.8 6.8 9.2 11.3 7.4 9.2 6.3 7.3 6.4 6.2 8.5 7.3 13.1 35.3 42.8 10.1 22.9 27.4 44.7 125.9 76.8 4.3 22.6 72.6 10.4 35.8 41.9 29.5 4.2 12.7 25.0 14.5 43.0 30.5 17.7 56.0 19.5 14.2 7.7 37.0 20.3 33.0 9.4 13.2 23.0 67.3 66.1 22.3 5.7 16.4 11.7 1.7 15.5 9.3 16.2 11.4 23.5 14.5 6.5 27.5 23.2 8.4 9.0 2.1 4.1 9.5 2.7 44.9 8.6 5.3 53.8 37.5 17.5 26.1 28.2 7.9 0.0 20.4 14.0 116.6 83.4 36.2 19.7 15.2 13.6 9.8 14.9 45.5 RBM10 "DXS8237E, GPATC9, GPATCH9, KIAA0122, S1-1, ZRANB5" ENSG00000182872 "RNA binding motif protein 10" P98175 X 47145221-47186813 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034972, HPA057372" Approved Enhanced "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" "HPA034972: AB_10602919, HPA057372: AB_2683421" "unprognostic (9.07e-2)" "prognostic favorable (6.71e-4)" "unprognostic (7.83e-2)" "unprognostic (1.61e-2)" "unprognostic (1.86e-1)" "unprognostic (3.04e-2)" "unprognostic (4.47e-3)" "unprognostic (8.11e-2)" "unprognostic (9.86e-3)" "unprognostic (1.76e-1)" "prognostic favorable (2.86e-6)" "unprognostic (1.18e-1)" "unprognostic (6.23e-3)" "unprognostic (3.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.40e-2)" "unprognostic (1.20e-3)" 23.7 31.1 28.5 19.9 28.8 32.5 23.9 32.6 36.4 33.3 26.6 28.8 18.1 29.5 12.4 34.2 31.5 12.1 30.8 28.5 28.4 30.0 32.2 23.9 25.1 28.2 27.9 40.6 32.2 15.9 38.0 17.3 28.3 33.8 11.3 14.8 23.6 15.6 26.5 27.1 27.8 12.5 26.6 33.9 26.4 12.8 29.3 23.6 33.1 12.4 15.9 28.3 29.9 31.9 50.1 52.5 48.9 58.8 25.7 21.0 57.3 36.8 21.4 37.2 35.8 46.4 39.8 60.1 22.0 25.6 47.5 47.7 64.9 46.1 20.4 61.6 59.0 45.1 65.1 48.8 37.5 46.0 52.1 27.7 22.0 61.2 49.8 26.5 40.4 56.5 38.3 47.0 23.0 74.9 84.8 78.2 81.9 37.1 58.0 74.0 41.0 62.2 27.7 42.9 58.6 44.5 56.0 41.6 35.6 29.3 50.9 45.7 35.8 43.7 54.9 47.8 39.5 48.4 42.9 49.5 38.8 32.8 62.3 13.5 8.1 11.4 12.7 10.7 12.0 11.2 10.2 10.8 9.2 11.1 10.0 9.7 7.5 9.9 15.8 10.7 12.7 9.3 28.5 28.8 32.6 36.4 28.5 28.4 28.2 27.9 28.3 26.6 29.3 31.9 17.4 41.7 36.9 22.5 21.6 11.1 22.4 15.0 22.8 26.7 16.5 16.8 36.6 21.5 28.8 9.2 14.6 34.2 21.3 32.2 11.7 20.5 1.3 23.6 20.1 19.6 35.8 14.9 14.8 17.7 28.5 20.2 31.6 31.5 24.1 29.1 16.8 23.3 19.7 21.9 15.4 31.5 10.2 14.2 10.0 2.7 18.0 15.4 16.0 8.4 19.9 14.7 20.6 15.1 18.1 19.8 20.8 25.6 22.5 18.7 23.1 14.3 28.8 27.0 0.0 21.4 21.8 10.7 8.7 23.4 10.5 46.1 23.8 19.7 34.2 18.1 RBM8A "BOV-1A, BOV-1B, BOV-1C, RBM8, RBM8B, Y14, ZNRP" ENSG00000265241 "RNA binding motif protein 8A" Q9Y5S9 1 145917714-145927678 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 735.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018403 Supported Supported "Nuclear speckles" NA NA 100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" "HPA018403: AB_1858908" "unprognostic (3.81e-1)" "unprognostic (3.99e-3)" "unprognostic (1.59e-1)" "unprognostic (6.83e-2)" "unprognostic (1.12e-1)" "unprognostic (3.16e-1)" "unprognostic (4.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.38e-1)" "unprognostic (8.79e-3)" "unprognostic (7.27e-3)" "prognostic unfavorable (1.55e-4)" "unprognostic (3.30e-3)" "unprognostic (2.18e-1)" "unprognostic (3.77e-2)" "unprognostic (2.02e-1)" "unprognostic (1.64e-3)" 86.1 74.9 37.2 105.4 39.1 214.7 82.3 38.7 43.0 69.6 35.6 70.5 70.1 67.7 49.3 163.6 62.2 58.0 73.0 36.8 41.7 81.6 77.5 72.8 126.4 39.7 39.8 72.0 59.9 78.4 65.8 85.3 40.8 66.4 56.4 45.0 79.2 48.2 214.9 92.0 69.2 57.7 42.1 81.6 67.5 71.3 40.0 120.7 68.8 100.1 123.7 112.8 80.4 43.9 377.0 300.7 268.8 215.7 94.6 92.2 330.0 224.3 150.7 315.0 230.1 400.0 277.4 342.0 344.9 155.3 166.5 252.5 289.3 245.3 257.0 305.6 275.7 264.2 229.2 299.8 133.6 446.6 222.6 102.2 180.8 283.0 300.3 137.4 238.1 291.9 405.2 314.7 246.2 1033.8 452.3 352.2 463.7 323.9 518.4 394.4 234.6 341.2 203.2 355.6 274.6 335.7 334.5 169.7 316.5 231.0 318.0 534.3 247.3 252.3 324.0 250.9 626.0 352.2 603.4 502.6 226.4 264.9 223.2 464.6 316.5 513.6 337.2 363.9 322.1 444.3 317.6 346.4 318.0 389.6 296.1 328.3 363.7 389.8 361.3 498.4 386.3 582.7 37.2 39.1 38.7 43.0 36.8 41.7 39.7 39.8 40.8 42.1 40.0 43.9 289.1 70.5 132.4 8.1 251.0 332.9 396.7 475.4 244.2 66.3 168.5 184.7 78.0 98.7 262.8 88.3 54.2 376.2 276.0 125.3 187.9 224.1 243.7 148.0 134.3 206.0 158.9 149.2 10.8 223.2 506.3 174.1 80.5 152.8 244.0 136.8 120.3 124.4 204.3 35.3 9.1 127.6 313.3 100.3 265.2 54.4 102.2 170.7 208.1 9.4 197.7 120.3 165.8 6.0 16.1 245.4 159.8 85.4 174.9 259.6 119.5 204.1 195.1 86.3 98.6 213.7 208.1 212.0 168.9 208.1 318.0 735.5 282.1 139.7 141.7 393.0 RBP4 ENSG00000138207 "Retinol binding protein 4" P02753 10 93591687-93601744 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Transport, Vision" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 11920.3" "Cell type enriched" "Detected in many" 12 "Hepatocytes: 12711.6" "Cancer enriched" "Detected in all" 27 "liver cancer: 3135.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 1117.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001641, CAB004555" Supported "Secreted to blood" NA NA 46100000000 210000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB004555: AB_670938, HPA001641: AB_1079795" "unprognostic (9.42e-3)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.60e-2)" "unprognostic (6.69e-4)" "prognostic favorable (1.74e-8)" "unprognostic (2.39e-1)" "unprognostic (5.76e-2)" "unprognostic (3.26e-2)" "unprognostic (3.26e-1)" "unprognostic (3.44e-1)" "unprognostic (7.14e-3)" "unprognostic (9.88e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (8.60e-2)" 730.7 32.4 30.2 6.2 34.4 1.1 394.2 12.4 48.1 5.8 12.4 11.2 4.8 2.3 0.9 1.1 2.1 7.5 16.7 32.2 113.0 142.8 11920.3 24.5 0.6 21.5 19.3 4.1 82.4 0.1 519.9 12.4 21.3 8.6 6.7 3.0 13.7 4.6 6.2 16.4 19.2 0.8 14.9 5.5 11.9 4.7 46.2 1.5 7.9 5.3 0.1 19.0 8.8 18.0 0.0 14.7 0.0 0.0 2.9 0.0 0.1 0.3 0.1 2.5 0.4 264.9 0.5 1.5 2.7 0.3 0.2 0.8 0.0 0.0 0.3 0.2 0.2 2.2 1.1 1117.2 0.2 9.2 0.2 18.7 0.5 0.7 0.0 0.0 0.0 0.0 1.4 0.2 1.2 0.0 0.1 7.3 1.3 2.4 121.7 0.4 7.0 0.0 0.0 0.6 0.9 0.2 9.6 0.0 0.0 0.6 0.5 0.8 0.4 0.0 7.8 0.2 0.3 0.9 0.3 3.7 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 34.4 12.4 48.1 32.2 113.0 21.5 19.3 21.3 14.9 46.2 18.0 9.1 0.0 4.2 0.3 17.2 0.8 0.5 0.0 0.0 0.0 2.1 6.7 0.7 999.4 0.6 23.9 6.2 0.3 0.2 21.9 97.8 7.8 2.8 1.6 3.1 10.8 62.5 152.4 5.8 0.2 22.6 10.5 0.0 22.1 0.0 0.0 158.1 12711.6 17.8 0.0 7.2 40.7 0.0 210.4 3.0 2.4 3.1 7.8 1.8 1.0 0.0 0.8 0.0 1.0 1.1 29.2 28.0 5.7 0.3 2.1 0.8 785.3 0.7 0.5 0.0 7.3 3.8 3.1 13.9 0.0 0.9 1.4 12.3 0.0 1.7 1.4 RBPJ "CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH" ENSG00000168214 "Recombination signal binding protein for immunoglobulin kappa J region" Q06330 4 26163455-26435131 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Notch signaling pathway, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 422.1;Oligodendrocytes: 378.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000251, HPA060647" Uncertain Supported Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA000251: , HPA060647: AB_2684337" "unprognostic (2.68e-1)" "unprognostic (2.71e-3)" "unprognostic (2.61e-1)" "prognostic favorable (2.98e-4)" "unprognostic (3.78e-2)" "unprognostic (1.37e-1)" "unprognostic (3.64e-3)" "unprognostic (1.66e-1)" "unprognostic (1.22e-1)" "unprognostic (3.01e-1)" "unprognostic (5.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.31e-3)" "unprognostic (1.46e-1)" "unprognostic (1.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.15e-3)" 40.9 18.3 28.1 33.0 44.2 51.3 28.4 34.2 38.5 31.9 27.7 33.2 20.2 36.4 18.0 28.5 23.6 25.5 21.8 29.0 37.6 21.4 17.9 31.3 27.5 41.7 38.5 34.2 22.3 26.2 12.9 54.4 39.0 28.0 28.1 33.1 19.3 22.5 21.7 26.0 22.7 38.0 32.2 25.7 25.4 28.7 36.4 27.8 24.8 28.9 26.5 31.8 21.7 58.9 68.2 19.1 60.0 39.0 91.5 138.8 44.9 54.4 47.0 50.9 60.1 14.5 36.4 56.0 34.1 36.2 39.5 12.2 51.9 33.4 98.1 30.4 28.4 42.5 24.2 27.9 47.9 76.9 35.9 64.0 28.5 104.9 39.7 70.3 28.5 34.3 43.0 21.5 93.2 20.1 54.5 76.4 163.5 20.3 30.3 48.0 112.4 25.4 26.8 22.4 84.5 36.5 28.0 20.6 24.3 54.4 22.0 53.3 38.5 50.5 25.2 86.3 51.9 40.2 51.9 55.7 132.3 86.3 43.4 23.8 94.6 112.9 31.4 77.8 42.6 37.2 49.8 34.1 136.4 33.4 41.4 35.9 220.5 70.9 77.1 31.5 68.1 68.6 28.1 44.2 34.2 38.5 29.0 37.6 41.7 38.5 39.0 32.2 36.4 58.9 72.5 48.1 66.8 62.0 54.6 152.8 86.2 104.6 55.8 94.6 48.9 51.2 44.2 62.9 83.3 46.0 129.3 102.7 47.3 26.6 74.3 64.3 44.4 54.5 96.3 73.2 78.4 46.9 81.7 65.4 74.4 129.0 29.0 62.8 57.0 130.7 65.3 53.1 365.2 85.8 85.9 51.0 59.0 208.5 422.1 56.7 135.5 234.2 80.0 60.9 125.1 95.0 44.3 215.1 378.1 76.5 35.1 84.2 54.9 113.7 44.9 55.4 67.5 102.9 85.5 71.7 95.8 134.7 158.4 45.9 109.3 83.9 102.8 57.0 47.0 75.7 RCBTB1 "CLLD7, CLLL7, FLJ10716" ENSG00000136144 "RCC1 and BTB domain containing protein 1" Q8NDN9 13 49531946-49585558 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 44.8;Cone photoreceptor cells: 64.6;Oligodendrocyte precursor cells: 75.4;Oligodendrocytes: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056783 Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA056783: AB_2683234" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (1.49e-1)" "unprognostic (5.70e-2)" "unprognostic (2.34e-2)" "unprognostic (2.40e-1)" "unprognostic (7.52e-2)" "prognostic favorable (5.51e-5)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.21e-5)" "unprognostic (1.17e-3)" "unprognostic (1.52e-1)" "prognostic favorable (1.75e-4)" "unprognostic (1.29e-1)" "unprognostic (1.42e-1)" "unprognostic (1.82e-1)" "unprognostic (5.49e-2)" 10.9 22.7 24.3 9.9 30.5 14.4 13.2 26.8 30.1 9.2 21.3 7.5 6.5 16.7 20.1 5.6 13.1 9.8 16.2 22.5 30.6 19.0 8.9 13.2 14.8 28.1 28.3 7.7 11.3 48.6 14.5 13.1 27.4 11.2 8.6 49.6 7.9 19.1 7.7 8.3 8.0 14.7 27.1 14.9 10.7 9.2 28.5 19.5 44.2 16.0 11.3 9.5 6.8 31.2 5.7 12.9 27.8 25.3 36.2 31.4 16.2 21.2 21.0 15.7 16.1 10.9 14.0 19.3 4.6 17.5 13.6 7.9 20.8 32.6 26.9 28.5 16.2 23.1 10.7 28.1 43.5 18.6 17.6 28.1 19.6 13.1 20.8 20.7 27.7 37.3 10.4 8.2 31.9 5.3 27.1 10.8 29.0 19.1 7.8 34.8 20.9 12.3 19.6 15.3 14.6 19.4 10.8 8.2 21.7 23.4 11.0 13.3 19.7 11.8 9.5 24.8 10.5 8.4 10.9 31.1 10.5 18.3 16.9 17.1 6.0 6.4 2.7 7.4 3.3 4.5 4.5 2.2 7.6 2.8 2.8 2.7 3.0 2.8 8.9 1.0 9.1 3.5 24.3 30.5 26.8 30.1 22.5 30.6 28.1 28.3 27.4 27.1 28.5 31.2 6.9 44.8 10.8 11.8 6.7 3.7 2.5 2.8 20.5 10.2 7.4 4.4 18.9 8.6 9.3 1.8 64.6 3.0 5.3 1.5 7.9 7.4 0.4 6.3 16.3 10.4 16.2 8.0 13.0 5.0 3.5 4.7 3.6 5.8 2.5 12.1 6.4 7.8 8.8 10.1 13.9 2.9 2.0 14.1 5.5 0.7 3.4 9.0 8.8 23.4 8.3 6.0 3.1 75.4 76.8 5.0 0.7 5.7 6.3 3.5 0.7 12.8 10.3 37.7 39.5 3.1 10.2 1.9 6.0 2.3 2.4 1.1 6.4 35.4 2.1 2.3 RDH11 "ARSDR1, MDT1, SDR7C1" ENSG00000072042 "Retinol dehydrogenase 11" Q8TC12 14 67676800-67695793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cataract, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 582.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 241.8;Muller glia cells: 299.7;Prostatic glandular cells: 285.7" "Cancer enriched" "Detected in all" 13 "prostate cancer: 286.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046011 Enhanced "Intracellular and membrane" NA NA 340000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "CAB046011: AB_11129613" "unprognostic (1.38e-1)" "unprognostic (6.86e-3)" "unprognostic (1.77e-1)" "prognostic favorable (2.62e-4)" "unprognostic (6.06e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (9.29e-2)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.58e-2)" "unprognostic (2.91e-2)" "unprognostic (1.27e-1)" "prognostic favorable (1.30e-7)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (4.74e-2)" 23.6 59.5 39.3 24.5 43.2 13.9 28.7 50.2 54.4 32.6 35.9 29.2 34.1 33.2 86.0 34.6 23.5 42.7 17.6 40.4 47.2 106.0 153.1 34.9 20.4 49.2 47.7 28.9 42.6 79.8 23.4 21.9 49.3 582.0 31.4 73.9 44.2 34.4 8.3 31.4 23.9 43.6 49.8 22.2 31.9 28.4 46.1 30.7 61.7 13.5 26.2 34.3 30.3 58.4 183.7 81.9 71.3 82.0 111.5 100.4 59.3 68.0 134.2 83.7 150.9 68.6 216.7 31.7 51.2 64.6 104.8 142.5 104.0 150.8 113.7 63.0 42.6 65.1 40.7 69.0 106.9 24.3 46.0 94.4 98.0 109.3 92.0 63.9 97.4 87.0 52.1 101.1 77.2 97.5 72.2 38.8 40.4 49.7 92.8 53.6 87.4 45.8 194.1 93.0 73.8 62.0 71.2 89.7 99.1 58.2 100.7 38.3 74.2 89.5 101.1 38.9 49.5 47.5 40.0 40.7 115.8 66.0 74.3 282.4 71.1 104.0 62.3 57.7 68.2 39.0 67.7 61.5 51.3 45.5 67.3 64.8 11.0 56.3 65.4 59.1 65.1 115.8 39.3 43.2 50.2 54.4 40.4 47.2 49.2 47.7 49.3 49.8 46.1 58.4 27.0 25.6 66.0 38.2 29.2 11.5 40.0 77.9 16.5 53.5 45.4 24.5 20.4 68.6 59.9 47.8 50.1 24.9 32.4 26.8 7.9 92.5 2.5 21.9 50.9 39.3 43.3 29.2 33.3 84.0 38.1 37.5 19.9 38.2 29.2 46.3 47.8 241.8 35.8 79.1 37.6 28.9 89.5 42.4 15.4 6.1 43.2 35.9 35.6 17.8 39.8 299.7 37.0 70.4 43.4 61.2 36.7 56.1 27.3 285.7 17.5 56.0 23.9 97.0 46.0 29.7 38.7 25.8 24.0 20.2 19.2 63.5 29.8 66.7 25.3 46.1 RECQL4 RecQ4 ENSG00000160957 "RecQ like helicase 4" O94761 8 144511288-144517845 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase" "Cancer-related genes, Cataract, Craniosynostosis, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;testis: 22.4" "Cell type enhanced" "Detected in many" "Spermatocytes: 23.5;Spermatogonia: 20.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "CAB017800, HPA025821" Supported Enhanced Nucleoplasm NA Yes "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB017800: , HPA025821: AB_1856168" "unprognostic (5.92e-2)" "unprognostic (1.86e-1)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (9.17e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.12e-2)" "unprognostic (4.12e-2)" "unprognostic (7.53e-2)" "unprognostic (2.65e-2)" "unprognostic (4.26e-2)" "unprognostic (1.12e-3)" "unprognostic (8.82e-3)" "unprognostic (1.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.34e-1)" 1.7 1.8 3.0 5.8 3.7 25.4 2.0 7.7 7.0 2.9 0.1 4.7 6.0 2.5 0.4 13.3 2.1 2.1 1.8 2.6 1.6 2.5 2.7 2.3 6.8 6.9 2.3 2.7 3.1 0.7 3.1 2.5 7.4 8.6 1.6 1.5 5.8 0.8 2.5 10.1 5.2 1.0 1.7 6.5 3.2 22.4 4.1 7.4 3.4 0.5 2.5 2.5 3.1 3.6 33.7 58.8 27.0 57.1 1.6 2.6 47.1 33.2 5.9 24.2 20.2 58.4 48.4 22.8 21.5 5.6 14.2 40.1 18.0 14.2 6.6 40.3 68.6 82.4 118.5 44.3 0.5 21.2 65.7 3.3 2.1 27.1 5.5 3.4 6.8 45.4 83.3 28.9 8.5 104.1 77.3 56.9 18.8 27.8 69.5 80.0 21.2 37.9 6.7 35.8 52.9 32.0 45.2 37.3 12.1 7.4 45.5 45.7 9.2 38.9 117.4 47.3 62.6 16.0 18.1 39.3 22.4 64.6 39.9 0.0 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.7 7.7 7.0 2.6 1.6 6.9 2.3 7.4 1.7 4.1 3.6 0.7 0.0 0.0 2.0 2.2 1.5 0.7 0.9 1.2 2.7 3.7 2.7 1.8 1.5 0.5 0.0 4.2 3.9 1.0 5.9 0.0 0.5 3.9 2.1 0.9 0.7 0.0 6.1 2.0 0.4 8.1 1.8 4.6 2.0 0.0 8.8 0.0 0.7 3.6 0.0 1.6 4.1 0.0 0.6 1.1 7.4 1.2 1.0 0.0 0.0 0.3 0.3 1.0 0.0 0.8 0.3 0.2 1.5 9.1 0.7 0.7 0.5 0.7 1.7 0.0 1.4 1.2 23.5 20.6 6.6 1.0 1.5 1.2 0.5 7.0 0.7 RELN "PRO1598, RL" ENSG00000189056 Reelin P78509 7 103471381-103989658 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein, Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 64.4" "Group enriched" "Detected in some" 8 "Hepatic stellate cells: 128.5;Inhibitory neurons: 372.4" "Cancer enhanced" "Detected in many" "liver cancer: 5.7" "Region enriched" "Detected in many" 10 "cerebellum: 64.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 16.2;PC-3: 8.6;SCLC-21H: 11.1;SH-SY5Y: 13.7;TIME: 33.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 110.0" HPA077891 Approved "Golgi apparatus,Vesicles" "Secreted in brain" NA NA 30000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Vesicles "HPA077891: " "unprognostic (1.42e-1)" "unprognostic (2.93e-3)" "unprognostic (4.31e-2)" "unprognostic (1.29e-4)" "unprognostic (1.30e-1)" "unprognostic (6.95e-2)" "unprognostic (1.85e-1)" "unprognostic (8.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.48e-2)" "unprognostic (3.31e-3)" "unprognostic (3.86e-1)" "unprognostic (2.02e-2)" "unprognostic (1.43e-2)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (3.06e-2)" 1.3 1.8 2.0 0.6 1.8 0.0 2.7 64.4 3.8 1.5 0.6 0.8 0.2 0.4 0.1 0.8 2.8 0.7 1.7 3.3 6.4 0.4 13.4 0.5 0.4 2.6 4.2 0.4 0.1 0.0 0.5 0.0 6.3 0.6 0.9 2.9 0.8 0.9 0.2 0.6 0.9 0.7 3.9 0.3 0.5 0.7 0.5 0.0 1.7 1.1 0.2 0.7 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 4.3 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 1.9 0.0 0.0 0.0 11.1 13.7 0.0 0.0 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.8 64.4 3.8 3.3 6.4 2.6 4.2 6.3 3.9 0.5 0.5 1.0 0.0 0.0 9.1 0.5 0.6 0.0 0.0 0.6 30.2 0.5 0.4 5.1 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 13.6 0.1 0.0 8.3 0.0 7.0 2.6 1.2 0.1 7.5 0.0 0.1 0.0 0.0 128.5 3.3 0.2 0.0 372.4 0.0 0.0 5.3 2.2 6.1 0.0 0.1 0.0 2.8 0.0 0.2 0.0 3.0 10.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.8 0.7 0.1 0.8 0.0 0.6 0.3 0.4 0.0 0.0 0.0 REN ENSG00000143839 Renin P00797 1 204154819-204190324 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "kidney: 162.2" "Cell type enhanced" "Detected in some" "Early spermatids: 6.8;Late spermatids: 28.4;Paneth cells: 5.6;Smooth muscle cells: 10.7;Urothelial cells: 7.0" "Cancer enriched" "Detected in many" 8 "renal cancer: 39.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.0;BJ: 2.0;HMC-1: 2.6;SK-BR-3: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA005131 Approved "Secreted to blood" NA NA 692000 10000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 33: Fibroblasts - ECM organization" "HPA005131: AB_1079174" "unprognostic (4.45e-2)" "unprognostic (3.35e-1)" "unprognostic (1.62e-1)" "unprognostic (8.58e-2)" "unprognostic (2.89e-1)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.37e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (6.49e-2)" 1.0 1.4 0.3 0.2 0.9 0.0 0.1 0.0 0.2 4.3 3.2 0.4 0.3 9.6 0.3 0.2 2.3 0.1 1.8 0.2 0.0 162.2 0.7 0.7 0.0 0.3 0.4 16.3 0.0 0.0 0.6 15.2 0.1 0.3 0.2 0.1 0.8 0.8 0.0 0.1 0.1 1.5 0.0 0.1 0.0 0.9 0.2 0.5 0.0 0.0 0.5 5.2 0.3 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.2 0.2 0.0 0.3 0.4 0.1 0.0 0.2 0.0 0.0 0.0 1.5 1.0 0.0 0.0 0.8 0.7 0.0 0.7 0.1 0.0 0.2 0.0 0.3 1.8 0.0 0.3 0.0 0.0 0.0 1.2 6.8 0.2 0.5 0.4 0.0 0.0 0.3 1.1 0.2 2.8 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 28.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 5.6 0.4 0.0 1.8 0.0 0.0 0.0 0.3 0.0 0.0 10.7 0.3 0.2 0.0 0.0 1.1 0.1 1.3 0.0 7.0 RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8" "Group enriched" "Detected in some" 4 "Horizontal cells: 79.1;Ionocytes: 26.4;Skeletal myocytes: 23.1" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 74.6;NB-4: 42.2;SH-SY5Y: 329.3;THP-1: 95.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 53.3;spinal cord: 19.4" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" 1.8 20.8 1.0 1.3 0.9 0.4 1.1 5.1 5.6 1.0 0.2 3.4 1.4 0.6 0.3 0.4 0.5 0.6 2.2 0.3 5.5 0.9 3.0 0.4 0.6 14.4 27.3 0.4 1.3 31.8 5.3 0.5 12.0 1.8 1.4 4.7 5.1 2.0 5.9 0.9 1.4 1.0 4.8 0.2 2.2 2.7 7.6 1.6 0.8 3.1 0.2 0.6 1.4 5.8 0.1 0.4 0.1 1.7 0.0 0.0 0.1 0.7 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.6 0.0 42.2 7.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.7 329.3 0.1 0.0 0.1 0.5 4.1 95.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.1 0.0 1.0 0.9 5.1 5.6 0.3 5.5 14.4 27.3 12.0 4.8 7.6 5.8 0.4 0.0 0.5 1.6 0.0 0.3 0.8 0.0 0.0 1.7 6.0 0.5 2.1 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 1.5 0.0 0.3 1.1 0.0 0.0 4.2 0.2 2.3 6.8 0.0 0.0 1.3 0.5 0.0 1.2 0.1 79.1 8.6 1.9 26.4 0.0 0.6 1.5 0.3 0.5 0.0 1.0 0.0 0.8 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.8 1.7 0.0 23.1 1.2 1.1 4.7 0.0 0.6 0.0 0.2 0.3 0.2 0.1 RHOA "ARH12, ARHA, Rho12, RHOH12" ENSG00000067560 "Ras homolog family member A" P61586 3 49359139-49412998 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Host-virus interaction" Hydrolase "Cancer-related genes, Disease variant, Ectodermal dysplasia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005052 Approved Supported "Plasma membrane,Cytosol" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB005052: AB_562216" "unprognostic (1.50e-1)" "unprognostic (3.38e-1)" "prognostic favorable (3.08e-4)" "unprognostic (8.75e-2)" "unprognostic (1.63e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.15e-4)" "unprognostic (1.39e-1)" "unprognostic (8.83e-2)" "unprognostic (9.44e-3)" "unprognostic (2.21e-2)" "unprognostic (4.29e-2)" "prognostic favorable (3.21e-6)" "unprognostic (5.14e-2)" "unprognostic (7.50e-2)" "unprognostic (1.57e-1)" "unprognostic (4.52e-2)" 452.4 315.0 234.6 357.9 258.6 473.4 360.0 257.1 274.1 310.4 237.4 351.9 274.6 293.8 298.6 362.6 269.2 267.1 269.6 220.8 271.2 286.9 274.5 430.9 396.3 282.9 245.8 297.2 225.3 269.4 164.3 396.8 287.2 244.5 369.3 113.3 238.0 315.6 331.0 281.3 281.0 416.9 259.3 329.1 292.1 154.1 257.5 387.7 326.3 298.5 454.9 358.2 273.6 292.5 470.4 406.1 500.9 512.7 569.9 858.9 370.8 930.1 735.7 790.3 722.4 347.6 527.4 721.8 251.6 1404.1 448.8 259.5 560.4 630.6 817.6 505.7 323.3 678.8 488.0 416.0 604.2 647.9 472.8 668.2 437.8 643.2 508.1 799.7 1038.0 391.9 361.1 437.9 967.5 254.3 717.3 739.0 441.4 548.2 497.1 325.5 451.4 610.5 701.9 559.6 167.7 387.3 599.0 464.5 495.4 499.4 301.7 819.6 972.1 558.4 483.2 737.2 725.7 388.0 775.6 754.8 567.9 691.6 678.3 716.9 1105.5 1160.5 480.1 1358.8 423.8 432.7 415.6 479.6 806.9 379.3 314.5 397.1 1282.7 440.9 1398.1 645.5 554.9 1884.8 234.6 258.6 257.1 274.1 220.8 271.2 282.9 245.8 287.2 259.3 257.5 292.5 502.8 387.8 265.2 20.5 374.6 270.9 260.0 236.1 251.6 47.1 239.4 223.1 141.1 178.7 220.9 180.3 6.2 355.8 373.1 447.2 340.4 339.5 48.2 174.2 243.7 413.8 234.4 319.3 26.1 347.8 709.8 386.2 313.9 201.0 257.3 141.6 312.7 173.2 760.0 82.4 27.0 344.9 191.2 771.9 495.8 55.6 335.2 683.7 327.3 52.5 710.0 219.9 389.3 24.6 51.4 398.0 354.6 407.7 375.7 334.1 341.3 350.8 201.1 40.8 276.1 354.1 450.1 264.4 253.6 390.8 279.6 525.2 359.5 299.1 347.7 371.4 RIC1 "bA207C16.1, KIAA1432" ENSG00000107036 "RIC1 homolog, RAB6A GEF complex partner 1" Q4ADV7 9 5629025-5776557 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 62.3;Excitatory neurons: 84.5;Inhibitory neurons: 79.6;Microglial cells: 98.4;Oligodendrocyte precursor cells: 69.9;Oligodendrocytes: 70.6;Plasma cells: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 73.3;HEL: 91.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051578 Supported NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" "HPA051578: AB_2681541" "unprognostic (1.78e-1)" "unprognostic (4.08e-2)" "unprognostic (3.13e-2)" "unprognostic (2.47e-2)" "unprognostic (4.51e-2)" "unprognostic (8.87e-2)" "unprognostic (8.59e-2)" "unprognostic (1.90e-1)" "unprognostic (3.87e-2)" "unprognostic (7.16e-2)" "unprognostic (8.96e-2)" "unprognostic (3.92e-2)" "unprognostic (3.74e-1)" "unprognostic (3.50e-2)" "unprognostic (4.67e-2)" "unprognostic (1.28e-1)" "unprognostic (5.77e-2)" 11.8 7.2 3.2 12.7 7.3 13.2 9.8 10.2 5.2 11.6 11.1 8.4 10.0 11.6 8.7 11.4 8.8 11.4 6.9 4.2 5.6 7.5 9.9 10.1 17.3 7.3 5.5 10.3 10.5 8.9 4.9 14.3 7.4 8.2 9.4 7.4 11.3 10.5 17.6 13.5 9.3 13.3 4.3 11.8 7.9 11.6 6.3 14.8 11.3 15.7 16.5 11.0 10.0 10.1 18.5 10.7 18.3 12.6 20.8 24.1 15.3 26.1 24.0 17.6 22.8 9.8 3.9 41.8 3.1 27.1 7.0 8.8 13.9 14.4 24.4 73.3 9.2 91.5 23.3 10.6 17.2 14.4 15.7 22.7 9.7 12.1 18.7 20.1 21.2 13.0 5.5 48.5 14.7 4.6 11.9 26.0 9.2 7.0 5.3 22.8 12.0 16.9 9.2 7.1 5.0 12.4 14.2 8.8 7.3 29.1 7.9 24.1 20.5 14.2 17.7 8.0 12.4 13.4 18.0 51.8 5.8 5.5 4.9 0.3 0.6 0.5 0.3 1.0 0.4 0.7 0.4 0.5 0.5 0.2 0.2 0.3 0.3 1.0 0.5 0.7 0.5 0.5 3.2 7.3 10.2 5.2 4.2 5.6 7.3 5.5 7.4 4.3 6.3 10.1 11.7 9.6 4.8 62.3 45.9 0.0 5.8 0.0 42.1 7.1 6.9 5.5 4.4 10.0 0.0 0.0 4.2 7.4 12.1 5.6 1.9 3.9 9.6 8.1 12.8 8.7 3.6 17.9 84.5 5.4 4.6 13.5 25.0 10.1 5.1 7.6 9.7 10.7 7.8 21.9 79.6 2.7 0.0 25.7 0.0 9.5 8.7 19.8 0.0 98.4 20.8 2.5 7.2 69.9 70.6 5.6 2.7 6.4 80.1 6.1 7.0 3.3 0.7 5.9 13.1 10.1 11.1 8.0 4.1 32.0 0.0 7.3 15.3 6.4 2.8 8.1 RIPK4 "ANKK2, ANKRD3, DIK, PKK, RIP4" ENSG00000183421 "Receptor interacting serine/threonine kinase 4" P57078 21 41739369-41767089 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 72.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 52.3;Endometrial ciliated cells: 76.5;Gastric mucus-secreting cells: 61.2;Glandular and luminal cells: 174.2;Squamous epithelial cells: 71.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 32.2;GAMG: 41.2;HaCaT: 47.5;hTCEpi: 31.4;RPTEC TERT1: 28.3;RT4: 30.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA030942 Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA030942: AB_2732462" "unprognostic (8.93e-2)" "unprognostic (2.67e-1)" "unprognostic (6.32e-3)" "unprognostic (7.87e-2)" "unprognostic (1.24e-1)" "unprognostic (5.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.22e-5)" "prognostic unfavorable (3.48e-4)" "unprognostic (9.98e-2)" "prognostic favorable (6.52e-4)" "unprognostic (2.69e-1)" "unprognostic (2.95e-3)" "unprognostic (2.28e-1)" "unprognostic (2.78e-2)" 1.6 0.0 0.1 0.4 0.0 0.6 4.3 0.0 0.1 11.8 3.7 3.1 9.7 1.1 2.4 72.2 5.8 5.2 1.5 0.1 0.1 11.5 19.1 4.2 0.1 0.3 0.6 0.1 14.3 7.4 10.8 2.3 0.1 10.7 2.0 0.6 14.8 9.8 0.0 21.5 13.6 0.1 0.1 0.0 15.5 2.0 0.1 7.8 7.9 0.0 5.2 6.3 22.3 0.1 14.3 9.0 0.0 0.0 0.0 0.0 13.7 0.1 0.1 0.2 0.2 23.5 32.2 0.0 13.3 2.9 41.2 47.5 0.7 19.2 0.0 0.0 9.4 0.0 6.9 8.8 0.0 0.0 0.0 0.0 31.4 0.2 4.2 0.0 0.0 14.3 0.0 0.0 0.0 10.3 2.0 0.0 0.8 9.3 26.1 0.0 0.0 2.3 28.3 30.8 4.5 0.3 15.5 15.7 15.1 1.3 9.6 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 4.2 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.6 0.1 0.1 0.1 0.1 0.1 28.9 9.1 0.0 0.1 15.8 27.4 24.0 52.3 0.0 13.0 12.4 1.1 17.2 28.0 3.7 0.0 8.3 0.3 22.8 9.8 12.4 1.5 76.5 16.9 0.9 22.7 0.0 0.0 10.4 5.1 0.6 61.2 174.2 2.5 0.0 0.0 17.0 1.0 0.0 0.0 14.2 16.2 0.6 1.4 1.6 0.0 0.9 7.2 0.0 0.0 0.4 0.0 0.0 0.0 19.0 11.8 0.0 0.0 24.0 26.5 13.5 22.2 0.9 0.0 0.0 1.3 1.4 2.5 71.2 15.2 2.5 1.5 0.0 11.2 24.1 RIPPLY2 "C6orf159, dJ237I15.1" ENSG00000203877 "Ripply transcriptional repressor 2" Q5TAB7 6 83853266-83857515 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 21.2;choroid plexus: 9.6;pituitary gland: 11.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 12.0;Excitatory neurons: 10.0;Horizontal cells: 11.8;Inhibitory neurons: 10.5;Oligodendrocyte precursor cells: 13.0;Rod photoreceptor cells: 8.5" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 19.1;HEL: 6.2;SCLC-21H: 26.0;SH-SY5Y: 17.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047454 Uncertain NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "HPA047454: AB_2680053" "unprognostic (2.09e-1)" "unprognostic (7.43e-2)" "unprognostic (2.51e-1)" "unprognostic (1.20e-3)" "unprognostic (2.69e-3)" "unprognostic (3.66e-1)" "unprognostic (6.94e-3)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.74e-1)" 0.3 1.4 13.8 0.2 14.4 0.0 0.2 17.9 21.2 0.9 9.6 1.3 0.2 0.8 0.0 0.2 0.5 0.3 0.2 14.6 14.6 0.2 0.0 0.1 0.0 13.9 12.7 0.4 1.1 0.0 11.2 0.0 13.8 0.7 0.2 4.2 0.1 0.4 0.3 0.1 0.4 0.3 13.3 0.0 0.7 0.8 13.5 0.0 0.2 0.0 0.0 1.4 0.5 14.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.7 19.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 1.5 0.0 0.0 1.1 26.0 17.7 1.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 14.4 17.9 21.2 14.6 14.6 13.9 12.7 13.8 13.3 13.5 14.2 0.2 0.0 0.0 2.0 0.0 0.0 0.4 0.3 1.8 12.0 0.0 0.1 3.5 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.3 1.8 0.0 10.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 10.5 0.0 4.1 0.0 0.3 0.5 0.3 0.0 0.0 1.0 0.0 1.4 0.0 13.0 4.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 8.5 0.0 2.9 1.0 0.8 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 RIT1 "MGC125864, MGC125865, RIBB, RIT, ROC1" ENSG00000143622 "Ras like without CAAX 1" Q92963 1 155897808-155911404 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 80.7" "Cell type enhanced" "Detected in all" "Langerhans cells: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053249 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" "HPA053249: AB_2682089" "unprognostic (1.84e-1)" "unprognostic (1.07e-1)" "unprognostic (7.27e-2)" "unprognostic (3.66e-2)" "unprognostic (1.35e-2)" "unprognostic (3.11e-2)" "prognostic unfavorable (8.64e-6)" "unprognostic (3.80e-2)" "unprognostic (4.99e-2)" "unprognostic (1.12e-1)" "unprognostic (6.45e-2)" "unprognostic (2.19e-2)" "unprognostic (9.22e-3)" "unprognostic (4.82e-2)" "unprognostic (3.74e-1)" "unprognostic (1.51e-1)" "unprognostic (2.33e-3)" 19.8 13.8 10.7 22.9 12.1 80.7 13.3 12.0 13.0 16.6 12.1 14.0 12.7 14.8 15.4 37.3 10.8 18.5 15.7 10.3 11.8 25.1 12.2 22.7 18.3 13.5 12.7 12.8 13.8 16.5 11.0 23.0 13.3 13.8 14.3 16.0 14.4 18.0 10.8 12.8 12.5 21.3 11.6 21.7 19.7 12.2 12.8 21.5 13.4 16.5 23.6 23.6 21.9 13.3 21.0 22.9 42.3 21.7 21.5 26.6 12.0 37.2 37.4 35.2 35.4 24.1 40.0 9.6 50.0 43.9 25.3 24.7 32.0 18.5 29.4 12.9 16.4 21.0 24.4 15.6 55.7 22.5 37.9 37.1 22.5 40.9 27.4 47.7 48.7 19.7 21.0 26.3 54.3 27.3 30.7 14.9 23.0 36.2 13.9 24.0 33.3 19.6 29.9 44.2 19.7 30.7 27.1 51.1 34.8 76.9 37.3 29.4 62.5 31.7 22.3 27.3 30.7 31.1 30.9 38.8 33.9 22.8 43.0 22.8 41.0 46.9 19.5 25.5 15.6 16.9 16.8 18.5 31.1 17.1 20.2 18.1 106.3 28.8 29.3 12.5 23.8 30.0 10.7 12.1 12.0 13.0 10.3 11.8 13.5 12.7 13.3 11.6 12.8 13.3 45.8 48.1 23.9 12.4 22.4 28.9 36.5 43.7 21.6 8.1 17.4 12.3 14.2 8.6 40.4 18.4 10.4 14.5 41.8 14.1 21.5 39.4 10.4 20.4 25.7 50.5 12.6 16.4 5.1 23.4 16.8 20.8 13.3 32.5 14.0 15.2 24.7 7.0 50.7 6.7 5.3 11.5 42.7 45.6 107.9 10.3 7.2 62.6 33.8 11.2 79.2 25.9 16.5 8.5 8.1 28.3 15.4 15.8 13.4 48.8 15.4 70.6 21.9 11.9 26.3 18.2 26.1 12.7 23.2 26.0 30.7 33.5 32.7 20.7 10.0 79.2 RNF125 FLJ20456 ENSG00000101695 "Ring finger protein 125" Q96EQ8 18 32018825-32073219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.4" "Cell type enhanced" "Detected in many" "dendritic cells: 169.6;Early spermatids: 90.7;NK-cells: 160.6;Oligodendrocytes: 64.3;T-cells: 114.8" "Cancer enhanced" "Detected in all" "testis cancer: 8.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 51.5;SK-MEL-30: 13.2;U-937: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041514 Uncertain Supported "Nucleoli,Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" Nucleoli "HPA041514: AB_10795596" "unprognostic (2.13e-2)" "unprognostic (2.05e-2)" "unprognostic (2.88e-1)" "unprognostic (3.93e-1)" "unprognostic (5.03e-1)" "unprognostic (4.50e-2)" "unprognostic (2.30e-3)" "unprognostic (6.15e-2)" "unprognostic (4.21e-2)" "unprognostic (3.24e-1)" "unprognostic (1.68e-1)" "unprognostic (4.35e-2)" "prognostic unfavorable (4.06e-4)" "unprognostic (2.99e-1)" "unprognostic (4.12e-1)" "unprognostic (1.82e-1)" "unprognostic (7.07e-3)" 10.2 1.3 2.0 5.2 3.7 18.4 6.3 2.7 2.7 3.9 1.6 5.0 10.5 2.9 0.5 2.5 3.4 3.3 2.6 1.9 2.3 1.0 12.5 4.7 7.0 3.6 3.2 1.4 3.1 1.7 0.3 3.7 3.4 1.8 6.4 0.3 2.2 1.4 2.3 4.9 11.3 3.3 2.6 5.9 3.4 1.0 3.8 5.3 1.4 2.9 4.0 3.0 1.7 6.2 1.2 0.1 0.2 0.4 0.5 0.8 1.0 0.1 0.0 0.0 0.0 0.1 2.5 0.1 1.2 0.1 0.4 0.9 1.6 1.2 0.2 6.6 2.6 0.3 0.4 0.3 0.1 8.9 51.5 1.6 2.4 0.0 2.8 0.3 0.4 2.7 0.1 1.9 0.1 2.0 2.3 8.2 4.2 8.9 1.5 9.2 0.6 0.2 0.5 0.5 0.9 0.3 0.2 0.1 13.2 1.6 1.3 4.2 0.2 0.1 0.7 0.1 0.1 5.9 0.2 0.1 0.6 11.5 6.9 13.3 4.5 4.5 15.0 2.5 9.9 2.5 12.0 12.8 4.2 2.3 9.5 12.3 1.9 15.5 2.8 4.3 13.7 6.9 2.0 3.7 2.7 2.7 1.9 2.3 3.6 3.2 3.4 2.6 3.8 6.2 62.2 3.2 5.8 3.3 16.3 9.8 3.1 1.0 14.2 0.8 5.3 3.7 2.1 4.3 3.8 12.9 0.0 0.4 169.6 24.6 1.9 1.0 90.7 4.9 2.1 28.4 1.2 15.8 2.7 1.8 0.1 5.3 8.6 13.4 18.9 0.2 12.5 25.1 10.5 0.0 3.0 8.3 0.0 19.2 12.6 17.4 2.8 18.4 1.8 30.9 23.8 0.7 160.6 3.5 64.3 1.1 4.5 0.0 49.9 2.7 41.4 4.5 1.7 0.9 0.0 3.2 3.2 0.5 1.8 5.8 6.8 0.8 114.8 0.2 14.7 2.4 RNF135 MGC13061 ENSG00000181481 "Ring finger protein 135" Q8IUD6 17 30970984-30999911 "Enzymes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 73.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 63.3" "Low region specificity" "Detected in all" "HPA021576, HPA052404" Approved Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA021576: AB_1856331, HPA052404: AB_2681817" "unprognostic (1.13e-1)" "unprognostic (1.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.33e-2)" "unprognostic (2.68e-2)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "unprognostic (4.60e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (6.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-1)" "unprognostic (4.47e-1)" 20.9 12.9 11.1 13.5 12.5 11.6 18.6 11.2 14.2 16.0 15.1 17.5 13.6 13.3 16.5 22.4 15.7 9.6 8.5 10.4 11.3 21.6 8.6 15.5 13.9 13.9 13.2 12.6 13.5 16.8 5.6 18.1 12.4 14.0 18.0 2.3 15.2 15.2 7.4 26.2 13.9 13.7 12.8 25.8 11.9 5.1 16.4 7.9 15.8 10.1 12.6 14.8 17.3 13.8 12.7 25.6 1.5 25.4 34.0 28.5 22.7 9.7 14.9 9.4 8.4 0.0 9.4 11.5 14.8 19.0 17.0 17.0 13.2 12.1 7.8 10.0 5.6 4.8 8.1 0.0 24.3 12.8 10.7 27.7 63.3 10.1 33.5 16.1 15.8 0.0 0.0 34.9 15.6 17.0 0.1 13.5 10.5 25.7 14.4 27.9 0.0 39.2 13.6 18.2 9.8 0.5 14.9 5.9 14.9 16.6 39.4 20.2 13.3 0.0 3.5 15.6 11.5 0.4 1.3 7.3 16.5 22.1 13.3 25.3 61.6 31.3 12.8 57.3 7.2 28.4 6.8 6.8 46.4 28.4 3.7 6.2 54.0 13.9 70.2 17.1 10.1 29.2 11.1 12.5 11.2 14.2 10.4 11.3 13.9 13.2 12.4 12.8 16.4 13.8 14.1 3.2 5.9 7.8 14.1 9.3 13.4 16.8 22.2 0.1 13.1 15.0 4.0 7.2 7.8 11.0 0.0 47.5 10.5 23.4 29.4 9.9 0.4 14.5 12.8 13.2 4.9 11.2 0.8 18.6 37.1 13.2 5.6 12.4 1.3 14.1 25.4 2.7 51.1 0.0 1.0 12.0 8.2 73.9 8.4 1.6 16.8 35.5 16.0 26.2 45.3 3.9 19.6 9.0 0.7 11.9 13.1 15.4 9.0 22.2 27.5 49.3 10.4 0.6 26.3 8.2 14.2 0.7 4.0 24.1 14.6 43.6 7.5 10.6 14.6 11.2 ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 181.5;Endothelial cells: 119.7;Hepatic stellate cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 247.6;TIME: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 380000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA065212: AB_2685434" "unprognostic (2.86e-1)" "unprognostic (9.35e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (6.97e-2)" "prognostic favorable (4.85e-4)" "unprognostic (7.94e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (2.17e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.55e-1)" "unprognostic (4.63e-1)" "unprognostic (5.15e-2)" 41.4 7.2 11.4 6.6 9.6 0.2 31.8 9.0 9.4 10.0 5.8 6.5 2.9 10.9 2.1 5.5 10.3 9.7 25.8 7.9 9.2 18.5 5.3 34.8 7.8 11.3 10.7 4.1 4.3 4.7 4.6 28.6 11.2 7.0 1.7 0.2 4.1 4.6 13.9 6.9 7.3 9.9 9.5 43.5 6.3 1.4 13.2 1.8 16.7 11.9 2.0 9.4 7.0 8.6 0.4 0.0 0.4 0.0 0.0 1.1 0.1 0.2 3.1 0.7 1.5 0.0 0.0 0.0 23.6 0.1 1.0 0.0 0.0 0.4 1.2 0.0 0.0 0.9 0.0 0.1 0.6 0.0 0.0 0.1 0.0 8.9 3.0 0.4 247.6 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 224.8 1.2 0.6 0.3 1.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 9.6 9.0 9.4 7.9 9.2 11.3 10.7 11.2 9.5 13.2 8.6 181.5 0.0 4.2 2.3 1.6 2.2 1.0 0.2 0.6 0.2 0.6 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.5 0.2 0.3 119.7 0.0 4.0 0.0 0.2 0.0 5.2 0.0 0.3 2.5 0.6 148.9 1.5 0.1 0.0 0.0 0.0 0.0 8.1 3.7 1.7 4.4 2.8 1.8 20.6 0.1 1.1 0.0 0.5 0.1 0.1 0.0 1.2 2.6 0.3 0.0 0.0 0.0 5.2 0.0 4.5 2.1 0.0 0.1 0.6 1.3 0.0 0.9 2.0 0.1 0.2 ROR2 "BDB, BDB1, NTRKR2" ENSG00000169071 "Receptor tyrosine kinase like orphan receptor 2" Q01974 9 91563091-91950228 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 18.4;Endometrial stromal cells: 19.3;Fibroblasts: 14.4;Inhibitory neurons: 18.6;Microglial cells: 15.9;Oligodendrocyte precursor cells: 27.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 6 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "AF22: 24.5;HHSteC: 63.1;HSkMC: 52.2;U-266/70: 38.3;U-266/84: 27.5" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 7 "cerebellum: 7.2;spinal cord: 3.7" HPA021868 Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA021868: AB_1856406" "unprognostic (9.38e-3)" "unprognostic (4.69e-1)" "unprognostic (2.26e-1)" "unprognostic (8.48e-3)" "unprognostic (1.23e-1)" "unprognostic (2.38e-1)" "unprognostic (2.06e-1)" "unprognostic (1.31e-1)" "unprognostic (8.03e-2)" "unprognostic (2.03e-1)" "unprognostic (5.76e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (9.86e-7)" "unprognostic (2.16e-3)" "unprognostic (9.13e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (1.25e-2)" 6.9 5.7 0.8 3.9 0.6 0.1 4.4 0.4 0.5 18.7 28.2 32.7 2.2 23.7 1.5 8.2 11.6 8.6 11.1 1.4 0.8 1.4 0.5 5.5 0.5 1.7 2.1 13.9 1.6 16.6 1.6 3.5 0.9 13.9 2.2 1.0 1.6 13.3 0.3 4.2 7.7 11.0 1.2 3.3 12.8 3.4 1.2 3.0 5.6 0.7 1.0 17.5 10.6 0.7 0.0 0.2 24.5 0.0 5.3 0.5 6.8 0.4 6.3 4.0 7.8 0.0 0.0 0.0 0.1 0.8 3.9 0.2 5.2 0.0 1.7 0.0 4.2 0.0 18.3 0.0 63.1 0.0 0.0 52.2 0.0 5.6 0.0 0.0 0.0 0.2 14.7 0.0 0.0 0.4 0.1 3.6 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 7.2 0.6 0.0 0.0 5.0 14.8 0.0 0.0 0.0 4.8 2.0 0.0 38.3 27.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.4 0.5 1.4 0.8 1.7 2.1 0.9 1.2 1.2 0.7 0.3 0.0 0.0 1.6 0.1 3.1 11.3 0.9 1.2 1.4 3.7 3.0 8.2 1.5 0.2 0.0 0.0 0.4 0.0 0.5 0.0 2.5 4.5 18.4 19.3 1.4 3.0 0.0 1.4 1.5 0.2 14.4 2.6 7.5 1.3 0.1 0.4 0.0 0.8 0.0 18.6 2.8 0.0 0.0 4.8 8.6 5.9 0.4 5.4 15.9 1.6 7.4 0.0 27.6 0.4 0.6 1.6 9.1 0.1 8.6 0.0 0.0 0.2 0.5 6.6 0.0 2.9 2.3 14.3 0.1 2.3 0.4 0.7 0.4 0.8 5.3 RPGRIP1L "CORS3, FTM, JBTS7, KIAA1005, MKS5, NPHP8, PPP1R134" ENSG00000103494 "RPGRIP1 like" Q68CZ1 16 53598153-53703938 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 40.5;Excitatory neurons: 59.8;Respiratory ciliated cells: 85.9;Spermatocytes: 43.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039405, HPA040530" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA039405: AB_10794636, HPA040530: AB_2677023" "prognostic unfavorable (6.93e-4)" "unprognostic (1.52e-1)" "unprognostic (2.19e-3)" "unprognostic (2.26e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.26e-4)" "unprognostic (1.24e-1)" "unprognostic (1.05e-1)" "unprognostic (3.63e-1)" "unprognostic (1.05e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (5.95e-4)" "unprognostic (5.22e-3)" "unprognostic (1.52e-1)" "unprognostic (4.92e-4)" "unprognostic (5.95e-2)" 1.6 3.5 2.3 2.1 2.2 1.5 3.2 1.0 5.2 3.1 9.5 1.7 1.3 3.8 3.7 2.2 6.8 2.7 1.9 2.7 3.0 3.0 1.1 1.9 1.8 2.4 3.2 3.5 2.0 7.6 6.0 2.1 1.9 2.9 1.7 2.9 1.7 2.8 1.0 1.9 0.9 3.5 1.0 0.9 1.9 13.5 3.5 2.6 4.6 1.4 1.8 2.2 1.8 3.2 11.8 13.7 11.6 10.7 13.9 13.3 5.6 12.7 7.9 9.8 2.7 7.1 9.5 7.5 8.5 11.1 7.8 12.5 9.4 11.6 19.1 4.6 7.2 2.8 12.1 7.5 6.0 6.7 5.0 8.1 6.9 11.4 6.9 11.4 8.9 10.0 7.2 4.3 14.8 4.5 11.2 4.7 7.4 3.7 6.3 19.3 15.9 9.4 14.0 3.1 19.9 7.5 14.3 6.4 5.3 6.7 10.0 5.7 7.8 12.2 8.6 9.7 11.0 5.4 6.9 13.1 18.9 3.9 7.3 0.7 0.2 0.3 1.2 0.3 1.2 1.1 0.8 1.0 0.2 1.5 0.8 1.8 0.6 0.8 0.3 0.7 0.7 0.4 2.3 2.2 1.0 5.2 2.7 3.0 2.4 3.2 1.9 1.0 3.5 3.2 3.1 6.4 4.8 15.7 2.9 4.6 2.8 11.1 4.6 5.5 6.9 8.0 9.8 1.5 15.1 11.0 8.4 5.5 1.5 1.3 17.6 7.4 21.5 40.5 20.7 3.9 0.0 3.0 59.8 3.3 7.4 12.9 5.1 8.6 7.0 12.9 2.5 3.8 2.9 3.3 36.6 5.6 4.1 1.2 3.1 12.0 4.7 1.9 1.8 9.4 1.8 6.3 2.1 14.1 8.6 3.3 0.5 6.4 2.1 1.7 0.2 19.8 85.9 8.7 6.6 7.8 9.7 43.2 11.2 4.7 5.4 1.6 2.7 11.5 4.4 2.4 RPL13 "BBC1, D16S444E, L13" ENSG00000167526 "Ribosomal protein L13" P26373 16 89560677-89564542 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051702 Approved Enhanced "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 190000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 32: Non-specific - Translation" "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA051702: AB_2681579" "unprognostic (5.41e-3)" "unprognostic (1.69e-1)" "unprognostic (1.14e-2)" "prognostic favorable (6.26e-4)" "unprognostic (1.57e-2)" "unprognostic (3.68e-2)" "unprognostic (7.38e-2)" "unprognostic (2.37e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-2)" "unprognostic (2.14e-1)" "unprognostic (7.57e-2)" "prognostic unfavorable (6.64e-4)" "unprognostic (4.34e-2)" "unprognostic (7.10e-2)" "unprognostic (1.14e-1)" "unprognostic (9.30e-2)" 2508.9 1855.2 1068.8 1015.2 1070.1 2207.4 2514.6 1007.8 1300.0 2885.7 1027.9 2382.3 1082.7 1830.7 799.8 2804.1 2342.7 756.7 1661.7 984.6 1007.1 1722.4 2142.4 1560.6 2106.2 1129.1 1023.0 5001.9 4316.1 896.0 1581.0 636.9 1076.3 2852.9 719.0 215.3 2413.8 826.7 2404.7 4466.0 2067.4 689.9 1159.2 2545.7 2148.6 856.8 1078.9 1718.3 1609.7 1175.1 1635.1 2301.1 2682.5 1123.0 1402.1 1524.2 1063.0 1733.2 1869.8 3083.4 2218.9 863.7 1857.6 1768.8 712.9 2316.0 2113.8 1954.1 1729.3 1484.1 700.0 1903.0 1279.4 2281.5 873.2 551.7 3534.0 666.7 817.4 3149.0 3985.0 818.9 781.2 3770.4 4759.6 1136.6 2847.0 2870.3 1870.2 2424.6 2074.1 1084.5 1380.2 4385.7 2272.4 6404.2 2180.5 2755.6 1601.9 3323.5 1128.8 2786.0 2205.4 1162.1 1491.3 2176.3 1195.0 1544.6 2735.2 665.7 3044.3 4780.1 1101.8 1132.3 1218.4 1008.8 1211.3 1626.1 1668.7 2104.6 1479.4 2863.7 1220.5 1017.1 3191.4 507.1 3779.3 2446.7 7007.7 7792.3 6813.4 5173.6 3626.5 8215.0 8509.1 6722.0 323.4 4085.8 1910.1 5071.9 5277.8 13749.1 1068.8 1070.1 1007.8 1300.0 984.6 1007.1 1129.1 1023.0 1076.3 1159.2 1078.9 1123.0 3260.3 1804.5 3489.0 39.8 9318.5 12528.7 15921.0 7329.9 8523.7 675.1 10709.1 13191.6 465.3 3808.9 4064.9 1616.6 189.7 6201.2 5935.5 1800.0 4652.6 4068.5 4125.7 2011.7 5627.8 4627.9 2937.8 3784.5 39.1 10909.9 11178.8 4536.6 2934.8 2679.4 2651.1 6392.0 5119.5 4261.1 5228.5 249.0 52.5 6292.1 2089.4 7058.1 8832.3 12884.5 8244.9 5051.4 5457.0 66.5 7569.8 1941.5 5395.5 158.3 86.4 7077.2 4715.7 3652.3 4667.7 14016.4 5245.4 7448.2 1834.7 786.9 2084.0 5936.3 5693.8 1721.1 1052.9 9022.1 16171.5 6165.5 7831.2 7839.7 7465.8 15137.1 RPS6KA3 "CLS, HU-3, MRX19, RSK2" ENSG00000177189 "Ribosomal protein S6 kinase A3" P51812 X 20149911-20267519 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 236.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003221, CAB003853, CAB013520" Approved Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Cytosol" "CAB003853: AB_562343, CAB013520: AB_2533378, HPA003221: AB_1853553" "unprognostic (1.87e-2)" "unprognostic (1.03e-1)" "unprognostic (1.80e-2)" "unprognostic (4.26e-2)" "unprognostic (3.53e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-2)" "unprognostic (1.61e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (5.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (4.49e-3)" "unprognostic (3.91e-1)" "unprognostic (1.09e-1)" "unprognostic (2.22e-1)" 21.1 18.8 6.9 33.7 10.2 16.2 14.8 12.7 12.8 16.1 8.5 32.8 24.1 17.5 8.5 18.7 15.1 26.9 21.1 8.7 9.4 19.5 45.0 32.3 31.3 8.4 10.0 10.6 17.2 59.4 5.9 19.5 8.5 19.9 31.8 15.7 13.2 18.0 51.8 15.0 27.6 27.8 8.7 29.2 21.1 5.5 10.6 32.9 21.2 40.3 32.6 34.2 8.5 8.0 44.9 77.0 28.4 14.8 27.1 47.3 8.6 38.0 57.4 27.8 37.7 87.7 56.2 29.3 12.8 40.0 40.5 30.9 32.8 32.2 51.1 24.8 26.1 34.6 46.2 236.8 27.7 67.8 34.2 30.3 25.1 43.5 54.4 24.3 101.9 30.4 23.1 81.0 29.4 21.2 44.2 20.7 20.6 57.8 45.9 23.3 60.0 33.8 23.9 36.9 13.1 12.8 51.1 15.3 54.4 35.3 0.1 20.0 57.3 30.1 20.8 96.3 21.7 64.3 42.1 32.1 56.9 33.1 72.6 11.9 3.8 7.9 4.7 5.3 8.3 2.4 5.4 5.2 5.6 3.2 3.7 4.5 5.8 6.6 6.0 6.7 2.9 2.2 6.9 10.2 12.7 12.8 8.7 9.4 8.4 10.0 8.5 8.7 10.6 8.0 60.6 44.8 67.5 31.6 34.8 54.4 37.0 21.2 10.2 37.8 20.4 10.8 22.9 34.3 41.1 16.5 22.9 4.0 70.0 63.5 3.9 26.3 0.4 10.8 24.0 61.1 25.0 19.1 142.2 30.5 6.7 31.6 24.5 26.1 44.3 8.3 34.6 65.4 22.6 13.5 108.4 59.1 28.5 40.8 104.3 1.5 13.1 62.6 37.4 126.5 53.7 27.5 46.4 116.6 27.0 37.4 57.9 21.1 25.5 56.6 33.5 25.1 23.3 9.7 19.7 41.5 21.3 6.4 8.7 13.8 55.5 3.6 66.0 14.2 61.1 63.8 RPSA "37LRP, LAMR1, LRP, p40, SA" ENSG00000168028 "Ribosomal protein SA" P08865 3 39406716-39412542 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor, Ribonucleoprotein, Ribosomal protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" CAB009561 Approved Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Plasma membrane, Cytosol" "CAB009561: AB_2182543" "unprognostic (3.67e-3)" "unprognostic (2.92e-1)" "unprognostic (3.97e-2)" "unprognostic (3.72e-2)" "unprognostic (5.38e-2)" "unprognostic (5.10e-2)" "unprognostic (5.84e-3)" "unprognostic (2.54e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (8.56e-2)" "unprognostic (7.50e-2)" "unprognostic (2.91e-2)" "unprognostic (3.18e-1)" "unprognostic (2.77e-1)" "unprognostic (1.73e-1)" "unprognostic (1.46e-1)" 1063.0 929.1 813.4 685.7 824.8 1574.8 1068.4 782.0 979.1 1260.0 761.8 1158.4 605.8 1022.1 351.0 1922.5 1128.3 372.5 783.9 778.6 794.3 905.9 972.5 894.3 1281.4 817.8 809.6 2153.7 2616.3 605.5 813.4 468.8 812.9 1212.6 872.2 273.3 1039.7 446.9 1087.1 1529.4 1133.1 718.3 842.4 1525.8 1209.3 358.0 831.9 1259.9 862.6 730.4 1466.4 1127.5 1293.1 821.5 1800.4 1646.5 1367.5 2265.9 1203.3 2661.2 2155.0 1251.2 2005.9 2775.9 1611.8 1811.6 1513.7 3949.6 737.0 2535.3 747.6 695.4 2983.8 2945.7 2402.3 1459.6 1599.6 1783.6 1390.5 1750.2 2322.7 2546.4 1649.2 3043.3 4729.8 2147.2 3475.3 2030.8 2942.7 2343.5 1909.3 1883.8 2031.1 1282.1 3031.0 1960.4 4574.2 2756.9 2755.1 1412.2 1958.4 2974.8 2004.4 814.2 985.3 1989.0 674.8 5156.5 2202.9 1843.5 1509.0 3544.5 1156.6 845.2 1545.8 1422.3 3102.3 1440.6 2363.4 2437.5 1355.7 2481.7 1143.9 98.3 240.5 56.7 572.9 294.6 993.1 1010.3 942.1 758.8 654.2 951.8 1036.2 936.1 34.3 726.0 247.5 723.6 765.5 1499.7 813.4 824.8 782.0 979.1 778.6 794.3 817.8 809.6 812.9 842.4 831.9 821.5 532.1 519.2 800.2 10.7 2802.5 1802.5 2606.9 1585.5 2040.3 270.4 1864.7 1423.4 64.0 1095.2 906.4 325.5 95.9 2852.5 1768.9 625.4 992.0 1598.4 144.3 536.7 1178.5 891.2 1033.6 1733.9 21.3 3417.4 4473.1 927.1 821.6 747.7 778.4 1654.5 937.3 717.7 1608.4 173.3 21.5 1847.0 455.7 1304.9 1469.6 283.7 1240.5 1086.9 738.2 12.2 1605.2 621.1 1858.9 19.1 29.3 1889.5 1184.2 747.4 1501.8 2136.7 724.4 1257.1 476.2 364.4 473.3 1053.5 1002.2 352.2 1255.8 2879.8 1916.2 2420.7 2100.0 1539.2 2442.4 2884.6 RRAS2 TC21 ENSG00000133818 "RAS related 2" P62070 11 14277922-14364506 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010420, HPA050942" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "CAB010420: AB_2253855, HPA050942: AB_2681285" "unprognostic (6.13e-2)" "unprognostic (1.85e-1)" "unprognostic (1.92e-1)" "unprognostic (1.47e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (7.80e-4)" "prognostic unfavorable (3.31e-4)" "unprognostic (4.15e-2)" "unprognostic (1.59e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (4.50e-2)" "unprognostic (4.15e-1)" "unprognostic (9.02e-2)" "unprognostic (1.05e-1)" "unprognostic (6.80e-2)" "unprognostic (1.63e-1)" 30.8 14.1 8.0 16.1 8.0 5.2 21.2 9.7 10.7 21.7 14.9 22.3 20.8 19.7 9.2 15.4 14.2 11.9 44.4 12.0 10.5 39.3 39.1 22.9 28.3 7.0 8.1 18.3 18.2 17.2 8.5 29.4 8.0 20.1 18.7 12.1 18.0 19.3 40.8 12.1 39.5 18.0 6.3 16.3 17.7 25.1 10.4 14.4 29.0 34.0 37.7 23.4 14.0 6.3 89.3 38.2 35.7 30.8 122.0 121.1 52.8 309.1 160.7 260.5 328.1 78.0 108.7 102.2 46.8 209.0 84.3 97.1 61.0 110.8 260.5 88.7 49.6 6.8 21.5 62.4 133.6 0.3 0.7 129.5 205.0 104.2 331.2 106.5 131.7 24.8 45.9 0.2 229.3 43.5 21.5 5.6 98.3 18.2 31.4 19.0 118.5 1.9 133.7 48.8 9.7 18.4 74.7 46.0 42.5 119.9 30.6 6.2 303.1 139.6 74.0 272.1 85.1 0.2 0.2 48.4 56.0 0.1 29.0 2.1 0.0 0.0 5.5 0.0 2.4 11.8 1.0 2.8 0.0 6.6 0.5 2.1 0.4 3.8 0.0 0.2 0.0 0.9 8.0 8.0 9.7 10.7 12.0 10.5 7.0 8.1 8.0 6.3 10.4 6.3 6.6 19.2 18.9 14.4 57.8 69.3 76.2 17.7 23.9 5.5 22.6 13.7 31.5 40.0 20.6 18.4 0.0 36.5 31.2 30.5 23.5 46.5 55.2 25.8 16.0 15.2 19.1 3.2 32.8 18.4 58.0 29.7 12.8 34.7 8.9 15.6 13.6 33.4 8.2 13.5 35.4 16.0 14.2 2.4 12.0 45.2 16.4 2.3 26.6 9.4 2.0 21.7 56.7 28.6 4.9 57.1 30.1 11.3 22.0 120.3 89.9 112.9 15.0 10.1 19.7 20.7 21.4 39.5 42.1 20.3 49.9 29.0 29.5 13.3 20.8 96.5 RS1 "RS, XLRS1" ENSG00000102104 "Retinoschisin 1" O15537 X 18639688-18672108 "Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Cell adhesion, Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 207 "retina: 213.7" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 160.6;Rod photoreceptor cells: 162.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059546 Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA059546: AB_2684058" "unprognostic (8.31e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (2.39e-2)" "unprognostic (1.86e-1)" "unprognostic (4.80e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-2)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "unprognostic (4.77e-3)" "unprognostic (4.14e-1)" "unprognostic (7.03e-2)" "unprognostic (1.06e-1)" "unprognostic (3.06e-2)" "unprognostic (5.12e-2)" "unprognostic (2.04e-4)" 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 213.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 6.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 15.3 0.0 0.0 1.9 0.0 0.0 0.0 160.6 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 162.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 RSPO2 MGC35555 ENSG00000147655 "R-spondin 2" Q6UXX9 8 107899316-108083642 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" "Developmental protein, Heparin-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.0;intestine: 13.9;placenta: 17.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 75.3;Inhibitory neurons: 86.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.2;U-266/70: 4.2" "Group enriched" "Detected in many" 7 "amygdala: 7.9;cerebral cortex: 17.9;hippocampal formation: 21.3;white matter: 13.2" "Group enriched" "Detected in many" 4 "amygdala: 8.3;cerebral cortex: 7.7;hippocampal formation: 8.5;midbrain: 12.9;spinal cord: 7.7" "HPA024764, CAB025900, HPA053068" Uncertain "Secreted in other tissues" NA NA "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB025900: , HPA024764: AB_10603236, HPA053068: AB_2682031" "unprognostic (1.10e-2)" "unprognostic (2.18e-1)" "unprognostic (3.97e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.19e-1)" "unprognostic (8.33e-3)" "unprognostic (1.82e-1)" "unprognostic (9.48e-2)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (8.45e-2)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" 0.2 0.0 2.8 0.7 4.4 0.1 0.0 1.3 16.2 3.4 2.6 13.9 3.4 0.0 1.7 5.9 0.0 3.2 0.2 6.6 13.2 0.0 0.4 7.1 0.0 2.6 23.0 0.3 0.0 0.0 2.9 17.3 2.0 8.7 7.8 0.3 0.0 2.3 0.0 0.0 4.6 0.3 2.1 0.0 7.6 0.7 3.5 0.0 0.0 0.0 0.0 1.7 0.8 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.4 1.3 16.2 6.6 13.2 2.6 23.0 2.0 2.1 3.5 6.6 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 75.3 0.0 0.3 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 86.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 4.7 0.0 0.0 0.0 4.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.6 0.0 1.7 0.0 0.0 1.0 0.0 0.2 0.0 0.0 RSPO4 "C20orf182, dJ824F16.3" ENSG00000101282 "R-spondin 4" Q2I0M5 20 958452-1002311 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.0;lung: 12.6" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Early spermatids: 6.6;Late spermatids: 7.3;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.0;EFO-21: 2.0;fHDF/TERT166: 2.4;NTERA-2: 6.3;SK-BR-3: 4.3;U-2 OS: 6.9" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" HPA048887 Uncertain "Secreted in other tissues" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "HPA048887: AB_2680545" "unprognostic (2.36e-1)" "unprognostic (3.60e-3)" "unprognostic (2.88e-2)" "prognostic unfavorable (2.98e-6)" "unprognostic (8.93e-2)" "unprognostic (1.14e-3)" "unprognostic (1.05e-2)" "unprognostic (1.47e-1)" "unprognostic (6.50e-2)" "unprognostic (2.02e-2)" "unprognostic (5.26e-3)" "unprognostic (2.96e-1)" "unprognostic (5.68e-9)" "unprognostic (6.65e-3)" "unprognostic (4.41e-2)" "unprognostic (6.18e-3)" "unprognostic (2.22e-2)" 0.3 0.2 4.3 0.6 4.6 0.0 1.3 2.1 6.7 0.6 1.1 0.3 0.1 0.3 1.4 0.8 1.6 0.4 0.5 3.4 7.6 0.6 0.3 12.6 0.0 13.0 8.4 0.4 0.3 0.3 2.1 0.2 12.6 0.4 0.0 1.2 0.4 0.2 0.1 3.0 0.3 0.0 3.8 0.2 0.2 3.2 9.6 0.0 3.0 0.0 0.4 0.2 0.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 3.0 1.2 0.0 0.1 0.0 0.0 0.0 0.8 2.0 2.4 0.3 0.0 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 4.3 0.0 0.0 0.1 0.0 0.0 0.0 6.9 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 4.6 2.1 6.7 3.4 7.6 13.0 8.4 12.6 3.8 9.6 2.2 0.0 0.0 0.0 10.7 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 6.6 0.1 0.0 0.3 0.0 0.0 2.9 0.0 0.6 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.8 7.3 0.0 0.0 1.8 1.9 0.0 0.1 0.0 8.5 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 2.1 0.9 0.0 0.4 0.3 0.0 0.0 0.0 0.0 RSPRY1 KIAA1972 ENSG00000159579 "Ring finger and SPRY domain containing 1" Q96DX4 16 57186137-57240469 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003729 Approved "Secreted to blood" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "HPA003729: AB_10964215" "unprognostic (2.73e-2)" "unprognostic (7.10e-2)" "unprognostic (1.32e-3)" "unprognostic (5.32e-2)" "unprognostic (1.63e-3)" "prognostic unfavorable (8.21e-5)" "unprognostic (6.84e-2)" "unprognostic (1.36e-1)" "unprognostic (4.63e-2)" "unprognostic (1.29e-1)" "unprognostic (2.26e-2)" "unprognostic (1.01e-1)" "unprognostic (4.89e-2)" "unprognostic (4.68e-2)" "unprognostic (3.35e-1)" "unprognostic (6.47e-2)" "unprognostic (4.81e-3)" 10.1 8.9 8.8 10.1 10.1 7.0 13.2 9.4 9.5 15.1 19.0 14.4 16.0 13.1 12.6 11.7 11.6 16.0 8.6 8.2 9.1 16.1 19.7 9.5 13.4 10.0 9.7 14.4 18.5 15.3 8.3 15.1 9.3 13.8 16.2 8.5 11.5 14.0 9.1 9.7 16.2 15.3 8.6 9.7 13.4 21.8 10.6 17.5 17.3 10.6 17.3 16.1 9.2 11.7 17.0 25.7 39.5 20.4 24.6 30.8 23.5 29.7 30.5 39.1 31.0 27.4 21.8 23.8 37.6 39.7 27.0 21.6 34.7 28.6 44.4 16.2 14.4 12.7 18.9 39.5 32.1 22.7 33.5 37.3 27.7 38.4 53.6 29.6 53.5 27.2 21.3 9.6 34.3 9.9 38.7 15.3 25.6 28.4 29.1 48.9 27.2 22.0 46.6 17.1 13.4 29.8 47.8 17.8 12.3 22.4 17.5 22.9 37.8 27.9 27.2 17.6 24.6 25.0 24.7 38.6 24.5 22.0 30.3 27.6 22.5 30.1 24.8 24.7 22.6 26.1 22.7 22.9 26.0 24.0 26.2 25.2 24.5 26.4 36.3 16.5 30.0 18.2 8.8 10.1 9.4 9.5 8.2 9.1 10.0 9.7 9.3 8.6 10.6 11.7 18.6 32.1 13.1 22.5 24.0 34.0 21.0 27.5 38.7 17.1 28.5 17.3 17.5 42.9 23.2 18.4 10.4 26.9 18.9 27.4 25.4 25.2 107.2 22.2 36.7 23.8 21.5 24.8 22.0 23.4 37.7 29.2 25.5 28.9 10.8 31.1 22.5 41.8 17.3 15.2 25.6 32.9 28.5 22.9 23.8 65.9 20.2 19.8 14.2 19.7 25.1 19.7 15.5 36.2 35.8 25.5 15.5 21.4 21.2 29.1 29.5 28.1 23.3 18.2 6.6 25.5 25.2 60.9 52.3 27.9 37.1 27.9 21.8 37.7 23.5 23.0 RTTN DKFZP434G145 ENSG00000176225 Rotatin Q86VV8 18 70003031-70205726 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 69.3;Oligodendrocyte precursor cells: 48.7;Oligodendrocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTERT-HME1: 21.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041343, HPA041967, HPA075089" Uncertain Approved Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Centrosome "HPA041343: AB_10794409, HPA041967: AB_10796790, HPA075089: " "unprognostic (1.76e-1)" "unprognostic (2.13e-1)" "unprognostic (1.36e-1)" "unprognostic (4.11e-2)" "unprognostic (3.44e-2)" "unprognostic (6.16e-3)" "unprognostic (4.63e-3)" "unprognostic (2.36e-1)" "unprognostic (1.40e-1)" "unprognostic (4.66e-2)" "unprognostic (1.90e-1)" "unprognostic (8.25e-2)" "unprognostic (6.94e-3)" "unprognostic (1.07e-1)" "unprognostic (3.81e-1)" "unprognostic (1.32e-1)" "unprognostic (1.96e-2)" 1.4 1.2 3.5 1.6 5.0 3.1 2.1 3.6 3.4 1.5 2.1 1.3 1.1 1.8 1.5 1.1 1.6 1.2 2.8 2.6 3.0 2.3 2.7 1.6 2.2 4.5 4.0 2.7 1.8 1.7 0.8 1.6 5.1 1.1 1.5 4.1 1.3 0.6 1.8 1.3 1.3 1.0 4.2 2.0 1.3 3.3 6.0 3.6 0.9 1.1 1.9 0.9 1.1 7.1 4.4 6.6 9.4 2.7 1.8 2.0 3.9 7.5 3.4 6.8 7.0 2.5 2.5 3.8 1.0 4.7 6.0 5.4 6.9 11.0 11.1 13.1 3.0 4.1 5.9 3.1 1.3 7.7 4.0 1.6 10.9 7.2 21.2 3.1 4.2 5.8 4.3 8.4 6.1 2.0 7.4 2.1 1.8 1.0 5.8 6.0 8.6 3.9 1.1 3.2 4.0 4.3 4.6 2.6 2.8 6.2 2.8 4.4 3.4 8.8 2.3 3.1 5.7 4.1 3.8 7.8 5.1 4.9 6.0 0.2 0.2 0.1 0.2 0.0 0.4 0.6 0.4 0.3 0.0 0.2 0.6 0.3 0.1 0.3 0.0 0.2 0.3 0.1 3.5 5.0 3.6 3.4 2.6 3.0 4.5 4.0 5.1 4.2 6.0 7.1 6.1 0.0 8.6 19.6 7.1 1.5 1.7 10.1 1.8 8.2 3.9 3.9 5.0 1.5 5.7 0.0 0.0 4.0 4.9 2.9 0.0 1.1 10.6 6.0 5.2 3.4 0.0 4.2 25.4 1.6 1.9 4.0 6.1 6.0 5.1 10.9 1.8 3.7 2.3 16.8 25.8 1.5 2.0 1.3 1.4 3.2 2.1 3.3 0.0 69.3 1.3 1.9 3.1 48.7 110.8 2.0 2.4 1.9 14.7 1.1 2.2 4.1 1.7 9.7 13.1 5.1 4.0 10.6 6.7 3.5 1.7 3.0 5.8 2.5 2.6 2.3 RUNX2 "AML3, CBFA1, CCD, CCD1, PEBP2A1, PEBP2aA1" ENSG00000124813 "RUNX family transcription factor 2" Q13950 6 45328157-45664349 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 10.7" "Cell type enhanced" "Detected in many" "dendritic cells: 55.8;Early spermatids: 128.3;Inhibitory neurons: 95.2;Microglial cells: 128.4;Plasma cells: 44.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 22.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 39.3;Karpas-707: 62.3;RH-30: 51.8;U-698: 55.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB008374, HPA022040, CAB062561, CAB068226, HPA070715" Enhanced Enhanced Nucleoplasm No No "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB008374: AB_590789, CAB062561: AB_2665599, CAB068226: AB_2665598, HPA022040: AB_1846086, HPA070715: " "unprognostic (1.49e-1)" "unprognostic (8.90e-3)" "unprognostic (3.99e-2)" "unprognostic (2.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (3.06e-1)" "unprognostic (1.23e-1)" "unprognostic (3.70e-2)" "unprognostic (3.18e-1)" "prognostic unfavorable (3.97e-9)" "prognostic unfavorable (2.24e-4)" "unprognostic (5.52e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (6.66e-5)" 1.7 0.7 1.1 4.3 1.0 9.7 2.8 1.2 1.4 6.7 0.9 3.7 2.0 1.5 0.8 1.4 0.9 3.4 0.7 1.3 1.5 1.5 0.7 2.7 4.5 1.9 1.8 2.2 0.6 0.6 1.6 1.5 1.9 4.8 3.9 0.1 10.7 2.6 0.8 2.4 6.0 1.6 1.6 3.6 3.2 0.5 2.0 4.5 1.8 0.9 5.6 3.6 4.9 1.9 3.6 1.1 0.8 0.0 3.2 8.3 0.0 3.3 7.9 10.9 15.2 0.0 1.9 0.0 3.8 4.7 4.9 4.3 0.0 3.1 19.7 13.7 1.5 0.0 2.4 0.0 16.7 14.2 0.1 22.5 2.5 9.7 10.9 39.3 0.2 5.6 0.0 62.3 19.7 1.0 0.4 24.7 0.7 3.2 0.5 0.1 51.8 0.0 10.7 7.0 0.0 0.0 2.4 0.1 4.1 9.2 3.6 1.2 0.5 11.1 8.8 17.2 12.1 19.6 0.0 55.2 12.5 5.3 5.0 8.6 0.9 4.5 1.5 0.2 12.9 0.2 3.5 4.0 2.4 0.2 0.6 1.8 6.5 22.1 0.1 15.4 3.2 1.0 1.1 1.0 1.2 1.4 1.3 1.5 1.9 1.8 1.9 1.6 2.0 1.9 0.9 0.0 2.7 4.6 5.7 2.8 16.6 5.3 1.2 0.0 2.0 1.4 2.7 0.0 4.9 3.7 0.0 0.0 55.8 0.3 0.0 0.6 128.3 0.7 3.5 0.8 0.0 3.8 17.4 0.2 0.0 7.0 4.1 0.5 2.5 0.1 1.1 0.8 3.7 0.0 95.2 1.0 20.3 6.7 20.8 20.0 1.2 16.3 7.2 128.4 18.6 0.0 7.2 6.6 5.2 0.4 0.1 2.2 44.4 16.5 0.0 3.3 5.1 0.0 6.6 1.5 6.2 0.8 0.5 1.2 1.6 0.1 21.4 0.2 0.2 28.0 SALL1 "Hsal1, TBS, ZNF794" ENSG00000103449 "Spalt like transcription factor 1" Q9NSC2 16 51135975-51151367 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.0;kidney: 36.4;liver: 36.5" "Cell type enhanced" "Detected in some" "Astrocytes: 15.3;Cone photoreceptor cells: 25.0;Endometrial stromal cells: 17.5;Glandular and luminal cells: 14.3;Hepatocytes: 30.1;Microglial cells: 26.2;Oligodendrocytes: 47.6;Proximal tubular cells: 20.3" "Cancer enhanced" "Detected in many" "glioma: 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 29.5;BJ hTERT+: 25.3;NTERA-2: 48.0;RPTEC TERT1: 40.4;U-87 MG: 46.2" "Region enhanced" "Detected in all" "olfactory bulb: 52.6" "Low region specificity" "Detected in all" "HPA049829, HPA074673" Enhanced Approved "Nucleoplasm,Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nucleoli, Nuclear speckles, Cytosol" "HPA049829: AB_2680902, HPA074673: " "unprognostic (9.91e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-6)" "prognostic favorable (1.28e-4)" "unprognostic (2.55e-1)" "unprognostic (1.17e-1)" "unprognostic (1.96e-2)" "unprognostic (4.41e-3)" "unprognostic (1.71e-2)" "unprognostic (2.88e-1)" "unprognostic (1.48e-1)" "unprognostic (3.96e-1)" "prognostic favorable (1.91e-7)" "unprognostic (1.86e-1)" "unprognostic (2.14e-1)" "unprognostic (3.03e-2)" "unprognostic (1.76e-1)" 0.3 0.0 18.0 0.6 29.2 0.1 0.3 29.7 21.3 19.6 2.1 2.6 1.0 17.4 0.0 0.3 11.0 0.4 0.8 17.9 21.7 36.4 36.5 0.0 0.0 41.0 32.2 4.5 1.0 6.5 6.5 3.9 36.6 0.8 2.6 4.6 0.2 1.6 0.0 0.2 1.3 8.4 31.1 0.0 2.5 1.7 26.6 0.1 23.7 0.2 0.0 2.8 7.2 40.2 0.0 1.7 29.5 0.2 0.8 0.6 0.0 10.0 25.3 0.6 1.4 0.0 0.0 0.0 11.2 14.1 8.8 0.0 18.6 0.0 0.9 0.0 11.3 0.0 0.0 18.5 0.7 0.0 8.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 48.0 0.0 0.0 3.8 1.9 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 46.2 0.0 10.0 0.2 0.6 0.5 0.1 0.4 0.1 0.2 0.2 0.1 0.4 0.2 0.1 0.1 0.3 0.0 0.3 0.4 0.2 0.3 18.0 29.2 29.7 21.3 17.9 21.7 41.0 32.2 36.6 31.1 26.6 40.2 0.0 0.0 0.0 15.3 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 1.4 10.0 0.0 9.2 25.0 0.0 0.0 0.0 11.7 0.5 0.7 8.9 17.5 0.9 0.0 2.7 0.2 0.0 0.0 1.6 0.0 14.3 0.0 0.0 0.7 30.1 0.1 0.0 8.2 0.0 0.0 1.0 0.3 0.1 0.0 0.4 0.0 26.2 0.0 0.5 0.0 5.0 47.6 0.0 0.0 0.0 0.0 0.0 0.0 20.3 0.0 1.0 0.0 0.0 0.5 0.2 2.3 0.0 0.1 0.0 0.3 0.6 0.0 0.1 SALL2 "Hsal2, KIAA0360, ZNF795" ENSG00000165821 "Spalt like transcription factor 2" Q9Y467 14 21521080-21537216 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.1" "Cell type enhanced" "Detected in many" "Astrocytes: 13.4;Bipolar cells: 13.9;Horizontal cells: 13.5;Muller glia cells: 11.2;Oligodendrocyte precursor cells: 10.6" "Cancer enhanced" "Detected in many" "glioma: 16.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 109.2;NTERA-2: 85.7;SuSa: 36.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004162 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Vesicles Nucleoplasm "HPA004162: AB_2667155" "unprognostic (5.73e-2)" "unprognostic (7.88e-2)" "unprognostic (3.21e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (5.53e-2)" "unprognostic (4.58e-3)" "unprognostic (1.03e-1)" "unprognostic (1.15e-1)" "prognostic favorable (1.23e-4)" "unprognostic (7.98e-2)" "unprognostic (2.09e-1)" "unprognostic (5.28e-3)" "unprognostic (2.03e-1)" "unprognostic (3.75e-2)" "unprognostic (1.86e-1)" 3.9 5.4 40.2 1.4 37.7 0.2 5.5 43.2 31.0 13.1 16.6 13.3 1.7 13.5 6.3 2.9 12.7 3.2 5.4 29.4 43.7 6.2 0.9 4.5 1.7 41.3 45.2 17.2 4.3 20.6 27.0 1.2 36.9 7.0 2.1 16.9 3.1 9.2 1.5 2.6 6.7 9.5 39.2 2.8 6.0 1.6 49.1 6.5 10.5 2.8 1.7 8.7 6.3 28.7 0.1 2.4 109.2 24.2 1.9 1.6 0.0 2.1 2.7 7.1 7.2 2.3 1.2 0.1 2.2 3.2 3.1 0.2 24.5 2.7 10.0 2.0 12.5 0.0 0.7 2.2 3.2 0.0 0.1 7.3 0.9 3.4 0.0 18.4 2.2 10.9 16.6 0.0 6.2 2.1 16.0 0.1 85.7 0.1 0.5 14.3 2.3 0.0 8.3 11.6 30.4 17.3 0.0 0.6 0.3 36.2 9.2 0.2 0.0 0.9 11.5 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 0.3 0.0 0.0 0.5 1.1 0.0 0.1 0.0 0.5 0.5 0.1 40.2 37.7 43.2 31.0 29.4 43.7 41.3 45.2 36.9 39.2 49.1 28.7 0.8 3.2 3.6 13.4 0.0 0.6 0.6 1.1 8.0 13.9 3.4 2.8 0.9 2.8 1.5 5.5 8.4 0.1 0.2 0.0 1.9 1.8 0.3 0.5 3.2 1.0 0.0 0.4 2.5 0.0 0.1 3.9 0.0 0.4 0.0 7.2 2.5 0.1 0.1 13.5 9.3 0.0 4.1 0.0 0.3 0.7 5.0 0.2 0.0 0.0 0.0 11.2 0.0 10.6 2.6 0.3 0.0 6.0 0.2 0.4 0.0 0.8 0.0 2.8 0.0 3.9 3.0 0.0 0.5 1.0 0.6 0.1 0.8 3.9 0.0 0.1 SALL4 "dJ1112F19.1, ZNF797" ENSG00000101115 "Spalt like transcription factor 4" Q9UJQ4 20 51782331-51802521 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.9;thyroid gland: 5.8" "Cell type enriched" "Detected in some" 4 "Horizontal cells: 26.9" "Cancer enriched" "Detected in many" 11 "testis cancer: 22.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "NK-cell: 2.5" "Lineage enriched" "Detected in single" 9 "NK-cells: 2.5" "Cell line enhanced" "Detected in some" "AF22: 25.0;AN3-CA: 17.5;BEWO: 33.2;NTERA-2: 60.2;SiHa: 15.6;SuSa: 39.7" "Not detected" "Not detected" "HPA015291, HPA015791" Enhanced Enhanced Nucleoplasm Yes No "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA015291: AB_1856548, HPA015791: AB_1856547" "unprognostic (1.30e-1)" "unprognostic (2.35e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-3)" "unprognostic (3.55e-2)" "unprognostic (7.43e-2)" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" "unprognostic (9.23e-2)" "unprognostic (2.50e-2)" "unprognostic (2.39e-2)" "unprognostic (2.42e-8)" "unprognostic (5.90e-3)" "unprognostic (1.82e-1)" "unprognostic (5.00e-5)" "unprognostic (7.41e-2)" 0.2 0.3 0.2 0.2 0.2 0.8 0.2 0.4 0.2 0.2 0.3 0.2 0.1 0.2 0.4 0.2 0.2 0.0 0.1 0.2 0.4 0.8 1.6 0.2 0.1 0.2 0.3 0.1 2.1 2.0 0.5 0.2 0.2 2.4 0.2 0.5 0.9 0.2 0.1 0.2 0.4 0.1 0.2 0.5 0.2 3.9 0.3 0.0 5.8 0.0 0.1 0.4 0.1 0.4 0.0 1.7 25.0 17.5 0.0 0.1 33.2 0.0 0.2 0.1 0.3 9.0 0.2 0.0 0.3 0.3 0.3 4.3 0.2 0.1 0.3 0.4 0.0 0.0 7.0 0.4 0.1 0.0 1.9 0.7 0.5 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.0 1.8 0.0 0.1 60.2 0.2 0.4 2.3 0.0 0.0 0.0 0.5 5.7 3.1 15.6 0.1 1.5 39.7 0.1 1.0 0.0 0.9 3.3 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.2 0.2 0.4 0.2 0.3 0.2 0.2 0.3 0.4 0.1 0.0 2.0 1.6 0.0 0.0 1.1 0.1 0.0 0.4 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 3.6 0.0 0.2 0.1 0.2 1.2 0.0 4.1 0.2 0.0 0.4 0.0 0.4 0.0 0.2 0.0 0.6 0.2 26.9 3.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.2 1.0 2.0 2.0 0.2 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.4 0.0 0.2 0.2 0.7 5.5 0.0 0.0 0.0 0.0 0.1 0.0 1.2 SART3 "KIAA0156, p110, RP11-13G14, TIP110" ENSG00000075856 "Spliceosome associated factor 3, U4/U6 recycling protein" Q15020 12 108522214-108561400 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028840, HPA044322" Approved Supported Nucleoplasm No No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA028840: , HPA044322: AB_2678895" "unprognostic (1.72e-1)" "unprognostic (1.16e-1)" "unprognostic (7.59e-2)" "unprognostic (1.72e-1)" "unprognostic (2.00e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (6.32e-6)" "unprognostic (2.74e-1)" "prognostic unfavorable (8.74e-4)" "unprognostic (1.38e-1)" "unprognostic (7.88e-2)" "unprognostic (1.05e-1)" "unprognostic (1.23e-1)" "unprognostic (1.23e-3)" "unprognostic (7.91e-2)" "unprognostic (1.61e-1)" "unprognostic (6.36e-2)" 14.6 15.1 14.0 18.5 14.0 25.5 14.8 17.6 15.1 18.8 12.2 15.9 12.6 19.3 13.7 19.2 17.4 11.9 13.9 13.7 14.6 13.9 16.1 14.5 26.3 12.5 12.9 23.8 13.2 18.3 18.9 15.4 13.0 16.5 15.2 20.3 14.1 14.5 17.8 19.0 17.2 13.9 13.5 19.8 15.1 16.8 14.5 25.7 18.8 15.1 23.2 15.5 16.0 16.8 34.5 61.5 45.4 53.8 24.2 18.9 43.6 29.3 35.8 50.1 37.2 51.5 23.4 51.3 20.1 26.4 32.2 32.0 68.2 33.9 44.1 61.8 43.0 74.1 40.9 47.9 39.2 74.0 44.4 26.4 31.4 31.9 46.8 38.1 30.8 42.1 85.7 33.7 30.9 34.6 69.9 57.5 90.2 27.6 59.9 67.3 44.7 59.3 26.1 57.5 56.8 40.3 45.0 17.0 30.7 38.7 49.0 51.1 26.0 39.0 21.0 30.1 30.7 42.6 68.3 75.6 34.1 42.2 46.2 6.9 6.2 6.4 8.3 5.1 9.9 7.7 6.3 8.3 9.0 7.1 9.4 6.0 1.6 8.6 7.6 6.1 10.5 7.9 14.0 14.0 17.6 15.1 13.7 14.6 12.5 12.9 13.0 13.5 14.5 16.8 14.7 19.2 24.5 16.0 25.9 14.7 16.3 15.4 16.5 42.0 11.5 11.4 19.9 10.0 23.4 18.4 35.5 21.4 21.1 12.0 7.9 14.7 53.6 15.1 21.6 20.0 12.5 23.1 22.1 12.7 14.0 17.1 15.3 15.9 17.7 21.9 11.7 12.5 13.2 35.3 22.2 9.3 24.4 14.1 13.8 30.8 10.2 17.0 16.0 16.9 18.6 23.4 14.4 19.1 24.9 13.5 7.7 17.7 29.6 16.1 9.5 8.2 27.4 39.1 32.9 22.0 18.0 27.2 31.1 19.6 18.0 23.7 24.2 19.1 14.0 17.0 SASS6 "DKFZp761A078, FLJ22097, SAS-6, SAS6" ENSG00000156876 "SAS-6 centriolar assembly protein" Q6UVJ0 1 100083563-100132955 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028187 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA028187: AB_10602220" "unprognostic (1.57e-1)" "unprognostic (2.52e-1)" "unprognostic (3.07e-2)" "unprognostic (2.06e-2)" "unprognostic (1.31e-1)" "unprognostic (3.02e-3)" "unprognostic (1.21e-4)" "unprognostic (1.27e-1)" "unprognostic (8.43e-3)" "unprognostic (4.73e-2)" "unprognostic (6.56e-2)" "unprognostic (3.71e-2)" "unprognostic (7.76e-8)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" "unprognostic (1.20e-1)" "unprognostic (2.54e-1)" 1.3 1.2 1.0 2.9 1.2 6.0 2.8 1.6 1.5 1.6 0.8 2.2 2.8 2.0 2.2 2.1 1.4 1.0 1.0 0.8 1.0 1.0 1.4 1.3 4.2 1.1 1.2 1.8 1.4 3.9 1.6 2.0 1.1 2.1 3.0 5.7 1.8 1.5 1.3 2.1 2.2 1.8 1.1 2.1 2.1 6.7 1.0 4.3 1.5 0.9 3.6 1.4 1.6 1.3 17.0 5.2 13.1 11.5 1.5 2.6 19.3 10.7 4.7 13.5 15.6 9.0 8.5 18.5 8.0 3.7 8.0 14.8 18.0 6.5 18.6 8.9 17.8 16.2 10.9 11.3 0.9 26.8 14.5 1.3 2.8 11.4 9.0 2.7 7.3 12.2 25.8 17.6 6.7 4.8 22.2 12.9 17.5 11.1 10.7 16.1 25.9 9.4 6.5 8.1 9.5 14.0 9.9 17.0 8.7 9.4 8.6 15.9 3.8 9.5 11.6 10.9 14.9 7.4 18.5 24.6 7.7 17.7 5.3 3.9 0.1 1.0 0.7 0.6 0.9 1.6 0.8 0.7 0.5 0.7 0.7 0.6 0.7 0.6 0.5 0.2 0.9 0.3 1.0 1.2 1.6 1.5 0.8 1.0 1.1 1.2 1.1 1.1 1.0 1.3 7.2 0.0 2.3 8.5 12.8 4.0 2.8 7.1 6.8 19.4 8.4 9.4 2.9 7.2 5.9 1.8 16.7 13.6 13.5 2.4 1.9 7.5 15.7 7.4 5.8 5.8 4.2 33.2 7.6 5.6 17.3 7.0 7.1 5.4 5.7 15.0 6.8 3.1 9.1 8.4 9.6 4.8 14.2 8.4 4.7 6.2 8.1 5.8 1.8 5.6 6.1 13.3 20.6 5.0 16.1 6.2 2.7 10.9 19.7 4.5 2.2 4.3 4.9 23.0 0.0 12.6 5.9 77.4 36.0 11.9 4.1 5.1 7.9 4.0 8.8 2.1 SAT1 "SAT, SSAT" ENSG00000130066 "Spermidine/spermine N1-acetyltransferase 1" P21673 X 23783173-23786226 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 8151.3;Langerhans cells: 13855.3;Prostatic glandular cells: 7419.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 3422.0;non-classical monocyte: 2519.0" "Group enriched" "Detected in all" 9 "granulocytes: 3422.0;monocytes: 2519.0" "Cell line enhanced" "Detected in all" "HBEC3-KT: 551.5;hTERT-HME1: 821.9;RPTEC TERT1: 694.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB047343, HPA055312, CAB069914" Supported NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB047343: , CAB069914: AB_830224, HPA055312: AB_2682781" "unprognostic (4.19e-2)" "unprognostic (3.92e-2)" "unprognostic (6.41e-2)" "prognostic favorable (2.87e-4)" "unprognostic (8.58e-2)" "unprognostic (7.90e-3)" "unprognostic (8.52e-3)" "unprognostic (2.22e-2)" "unprognostic (2.81e-1)" "unprognostic (1.18e-1)" "unprognostic (8.38e-3)" "unprognostic (2.23e-1)" "unprognostic (7.58e-2)" "unprognostic (5.13e-2)" "unprognostic (1.61e-1)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" 843.8 307.2 171.6 568.4 175.0 1484.9 454.0 167.0 279.5 337.8 219.7 339.0 630.9 319.0 170.8 407.4 322.7 600.8 604.4 171.8 202.0 739.5 885.0 1252.9 431.3 186.2 178.6 197.9 229.3 268.7 548.5 603.5 188.6 413.1 364.3 108.3 786.6 342.2 66.2 200.1 509.5 175.4 185.5 706.6 562.6 116.2 197.7 231.8 757.0 79.0 333.4 536.2 241.6 206.6 62.2 123.1 30.8 48.3 256.0 103.8 83.6 89.2 149.8 21.7 50.2 59.0 179.3 102.7 160.0 21.1 172.4 91.9 16.4 551.5 78.8 34.1 74.3 49.9 60.0 503.5 327.5 48.8 46.1 216.2 412.0 169.0 821.9 197.2 181.5 16.4 21.4 88.4 63.8 59.1 35.9 219.1 20.6 455.2 56.3 30.0 19.8 126.1 694.6 126.0 8.7 8.9 91.2 204.8 179.2 222.3 31.5 10.7 68.9 175.6 8.9 106.6 44.7 37.1 9.6 23.1 104.8 28.8 34.2 557.6 720.4 478.9 66.0 1930.3 41.6 125.3 77.4 53.8 324.8 79.1 45.9 53.3 3422.0 33.8 2519.0 161.2 231.5 742.5 171.6 175.0 167.0 279.5 171.8 202.0 186.2 178.6 188.6 185.5 197.7 206.6 798.0 734.0 1585.4 98.9 875.4 2435.0 3753.4 8151.3 1203.6 54.9 895.9 574.4 454.2 574.7 5509.5 829.4 116.7 853.1 409.5 1249.8 1189.5 5869.5 17.3 3940.5 859.6 1554.6 526.9 195.2 40.3 3065.2 1643.7 1211.3 1347.1 5651.2 870.6 110.6 558.3 994.1 2115.2 72.3 77.6 852.3 3733.2 4693.0 13855.3 55.2 165.3 5207.7 3922.0 213.6 5274.6 501.9 189.5 90.5 14.2 2774.1 1293.8 92.2 1091.8 7419.8 1851.7 2065.2 4274.2 114.4 151.2 765.7 857.5 31.6 14.7 1022.4 1468.3 2880.9 899.3 260.2 804.4 6549.5 SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase O75845 11 121292681-121313410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.6" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 141.0;Hepatocytes: 307.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066283, HPA070248" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA066283: AB_2685648, HPA070248: AB_2686240" "unprognostic (4.78e-2)" "unprognostic (7.29e-2)" "unprognostic (2.26e-2)" "unprognostic (2.36e-1)" "unprognostic (3.98e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (2.79e-2)" "unprognostic (7.96e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (4.03e-2)" "unprognostic (3.18e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.07e-7)" "unprognostic (4.29e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (1.98e-1)" 28.6 35.3 18.4 12.6 20.4 5.7 56.6 37.1 29.3 20.7 17.6 23.2 48.2 15.1 73.2 39.6 16.5 18.2 22.0 19.9 29.9 49.1 393.6 24.6 13.5 42.9 28.0 16.9 21.5 48.6 15.6 14.7 39.1 101.4 19.9 29.5 22.4 56.6 7.7 13.8 24.7 16.2 32.2 8.8 21.7 24.3 24.6 13.5 23.9 13.0 19.5 21.5 27.1 36.5 26.5 14.3 184.8 39.5 72.1 59.9 27.8 27.8 53.5 18.2 32.4 83.1 95.9 25.4 89.0 32.3 156.6 100.8 59.2 70.9 18.1 12.5 80.0 34.6 73.4 64.4 57.9 24.8 12.5 51.0 57.4 60.4 60.2 15.6 29.8 22.8 25.0 34.6 89.0 27.4 9.4 29.2 59.8 74.4 39.7 13.2 51.0 21.6 133.6 116.5 51.1 28.8 73.4 14.6 38.0 125.4 62.2 38.6 58.3 19.0 29.7 32.5 14.0 6.4 11.2 33.3 7.0 49.5 33.5 7.8 3.7 1.0 3.5 4.9 5.9 4.4 4.7 4.2 6.5 4.1 6.8 6.7 0.3 5.3 3.6 7.7 5.5 2.6 18.4 20.4 37.1 29.3 19.9 29.9 42.9 28.0 39.1 32.2 24.6 36.5 10.4 19.2 31.9 23.8 62.6 9.7 49.9 48.9 14.8 26.8 33.7 12.4 20.8 18.6 40.8 20.2 31.3 15.9 47.5 26.4 5.9 24.1 3.0 11.5 8.8 15.7 14.4 18.1 29.6 28.9 16.7 16.3 18.3 19.6 17.7 11.1 141.0 307.1 21.0 23.5 29.4 15.3 59.0 22.1 17.0 1.3 19.3 17.6 19.6 20.6 15.6 38.7 13.4 27.6 34.0 19.3 18.8 17.0 20.9 50.1 24.1 15.8 18.7 28.3 13.1 12.9 14.7 6.7 12.7 36.2 15.5 18.6 56.5 42.8 13.3 54.4 SCARF2 "HUMZD58C02, SREC-II, SREC2" ENSG00000244486 "Scavenger receptor class F member 2" Q96GP6 22 20424584-20437826 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 44.8;Fibroblasts: 21.2;Leydig cells: 13.4;Peritubular cells: 17.7;Sertoli cells: 13.1;Smooth muscle cells: 19.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 25.5;SH-SY5Y: 28.5;SK-MEL-30: 31.7;U-138 MG: 38.7;U-2 OS: 40.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA035079 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 580000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 9: U-2 OS - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Nuclear bodies, Cytosol" "HPA035079: AB_10670287" "unprognostic (2.12e-1)" "unprognostic (2.16e-2)" "unprognostic (2.06e-2)" "unprognostic (1.06e-3)" "unprognostic (2.29e-1)" "unprognostic (2.92e-1)" "unprognostic (7.68e-2)" "unprognostic (7.87e-2)" "unprognostic (8.27e-2)" "unprognostic (2.18e-2)" "unprognostic (1.68e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (2.78e-5)" "unprognostic (4.38e-3)" "unprognostic (3.18e-2)" "unprognostic (3.00e-3)" "prognostic unfavorable (4.28e-4)" 15.1 5.4 2.4 1.9 2.6 0.4 10.7 0.5 3.3 19.1 4.1 10.0 1.3 22.4 0.5 3.6 15.5 3.6 10.3 2.1 3.9 10.6 3.6 23.2 1.3 5.1 3.2 20.2 4.0 0.4 5.4 3.7 2.2 15.5 0.3 0.1 4.6 4.5 3.1 10.1 6.0 2.2 2.0 9.4 7.8 2.7 4.7 0.2 11.8 0.4 0.2 13.3 13.2 1.3 0.7 0.4 5.8 10.1 3.4 4.8 2.3 25.5 10.8 6.2 3.3 0.1 0.1 0.4 14.6 12.7 0.4 0.2 3.4 0.1 0.7 0.9 21.6 2.1 0.5 4.9 21.3 0.0 1.1 8.2 0.1 3.0 1.5 3.0 3.0 0.1 0.2 0.2 2.2 1.1 0.0 0.5 7.8 0.0 3.3 0.6 16.1 0.0 0.1 0.1 2.5 28.5 0.1 0.0 31.7 1.1 0.9 0.1 3.7 38.7 40.7 1.0 5.9 1.2 0.5 0.4 0.1 0.5 19.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.4 2.6 0.5 3.3 2.1 3.9 5.1 3.2 2.2 2.0 4.7 1.3 3.6 0.0 0.0 1.6 0.1 2.8 1.6 0.7 0.0 2.9 0.3 0.9 44.8 0.0 0.3 0.0 2.1 0.4 0.3 0.1 0.0 0.0 0.3 2.6 8.9 10.5 0.0 0.0 1.9 0.0 1.6 21.2 1.5 1.0 0.0 0.6 3.9 0.7 0.7 0.0 5.2 0.2 0.0 0.8 2.4 0.5 13.4 0.4 3.6 6.5 0.0 0.3 1.0 3.0 1.1 0.0 0.1 17.7 0.2 7.1 0.0 0.2 4.2 0.8 13.1 1.4 19.5 1.1 0.7 0.3 2.7 0.4 1.2 2.1 0.2 0.6 SCYL2 "CVAK104, KIAA1360" ENSG00000136021 "SCY1 like pseudokinase 2" Q6P3W7 12 100267140-100341715 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021050 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "HPA021050: AB_1846175" "unprognostic (7.01e-3)" "unprognostic (3.04e-2)" "unprognostic (4.34e-3)" "unprognostic (4.01e-2)" "unprognostic (3.87e-2)" "unprognostic (1.07e-1)" "unprognostic (1.27e-2)" "unprognostic (8.19e-2)" "unprognostic (5.32e-2)" "unprognostic (1.31e-1)" "unprognostic (1.34e-2)" "unprognostic (1.93e-2)" "unprognostic (4.44e-1)" "unprognostic (2.72e-1)" "unprognostic (3.46e-1)" "unprognostic (1.60e-1)" "unprognostic (2.18e-1)" 13.4 13.4 6.2 16.4 7.3 21.5 16.8 9.9 8.2 14.0 7.6 22.9 20.2 14.5 20.9 22.1 10.9 16.2 14.9 7.6 8.6 21.2 28.7 17.2 15.0 5.6 5.4 8.8 17.9 20.9 12.9 21.0 6.3 17.0 26.9 16.7 15.7 15.9 15.6 13.7 17.0 17.4 6.3 14.7 16.4 14.6 7.5 19.0 15.6 19.1 19.8 21.5 11.5 7.2 37.7 29.0 45.8 37.7 28.8 31.1 43.2 38.0 42.8 34.8 29.6 28.1 19.4 23.4 17.7 46.9 23.7 32.1 36.4 27.8 40.6 36.5 24.2 76.0 18.5 20.3 25.7 36.2 72.8 23.1 42.5 39.5 44.9 41.3 44.4 26.0 40.8 19.7 37.4 29.2 29.2 31.7 28.6 21.7 32.6 23.4 33.6 22.7 31.6 61.1 28.3 25.3 43.0 44.2 36.2 48.2 64.9 27.8 41.7 29.7 17.2 27.8 24.8 22.6 32.1 28.3 14.6 24.6 34.4 12.3 5.2 10.0 4.0 6.5 5.1 3.3 4.2 3.8 6.6 2.3 4.5 4.9 6.7 8.6 5.7 2.0 6.2 4.0 6.2 7.3 9.9 8.2 7.6 8.6 5.6 5.4 6.3 6.3 7.5 7.2 24.4 16.0 35.2 37.9 20.4 35.9 21.3 17.4 33.0 16.8 29.6 17.1 30.1 7.2 26.8 20.2 27.1 31.3 22.7 44.1 5.9 16.8 8.5 24.4 19.1 24.8 21.7 28.6 50.3 21.7 22.2 20.2 37.8 31.2 27.9 15.1 16.4 37.1 25.1 15.2 54.1 30.6 12.2 34.6 47.4 4.7 13.4 29.2 16.0 44.0 27.5 10.9 17.5 64.3 47.2 24.0 32.1 15.4 22.2 36.8 16.2 26.3 18.3 16.2 0.0 13.1 20.9 24.9 12.0 36.8 34.7 59.4 22.6 19.2 33.6 52.8 SDCCAG8 "BBS16, CCCAP, NPHP10, NY-CO-8, SLSN7" ENSG00000054282 "SHH signaling and ciliogenesis regulator SDCCAG8" Q86SQ7 1 243256034-243500091 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Obesity, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 284.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "WM-115: 29.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025737, HPA044477, HPA072495" Approved Enhanced Centrosome NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 4: Macrophages - Innate immune response" Centrosome "HPA025737: AB_2671761, HPA044477: AB_2678955, HPA072495: AB_2686527" "unprognostic (4.12e-1)" "unprognostic (3.94e-2)" "unprognostic (7.58e-2)" "unprognostic (2.86e-2)" "unprognostic (2.61e-1)" "unprognostic (3.78e-2)" "unprognostic (9.34e-2)" "unprognostic (3.95e-2)" "unprognostic (4.37e-2)" "unprognostic (5.97e-2)" "unprognostic (1.02e-1)" "unprognostic (2.64e-2)" "unprognostic (1.38e-3)" "unprognostic (1.13e-1)" "unprognostic (1.89e-1)" "unprognostic (3.68e-3)" "unprognostic (4.69e-2)" 11.6 9.8 7.1 3.8 7.6 3.5 11.3 7.1 7.4 9.6 6.8 8.4 2.9 7.9 7.3 8.0 9.4 7.5 8.8 7.6 7.1 9.3 7.4 11.8 5.2 8.6 7.9 11.0 14.3 7.0 11.6 4.5 7.7 8.9 3.1 3.7 8.4 3.8 12.1 8.1 7.6 3.0 8.3 8.3 8.4 5.3 7.7 3.3 17.1 2.3 2.7 8.9 8.9 8.9 6.2 5.4 2.0 3.8 7.3 3.4 6.3 4.4 3.4 2.1 1.7 4.9 10.9 2.4 6.5 3.7 0.7 2.2 0.6 4.9 2.0 3.7 6.9 2.3 3.7 2.0 3.7 2.2 5.1 7.0 6.2 4.8 7.7 7.9 5.5 5.2 3.2 3.3 3.9 1.9 0.9 4.9 1.2 9.4 9.5 3.1 1.1 2.1 7.5 4.1 5.6 5.7 4.3 2.6 10.6 0.9 4.3 2.8 5.2 6.8 1.5 2.4 2.5 5.1 2.7 1.2 3.0 4.1 29.9 7.6 7.8 6.6 3.8 8.0 2.8 5.2 4.3 5.3 7.1 6.9 6.1 4.2 4.7 9.0 4.5 5.6 3.8 3.8 7.1 7.6 7.1 7.4 7.6 7.1 8.6 7.9 7.7 8.3 7.7 8.9 30.6 41.7 103.6 139.7 39.0 37.2 39.6 59.1 56.9 69.8 34.9 37.1 28.5 50.1 52.0 40.5 87.6 48.1 16.1 16.5 76.3 63.1 17.8 60.9 31.6 36.2 31.9 23.3 170.5 30.0 86.3 38.5 24.5 31.4 49.9 29.8 45.7 27.8 130.1 65.6 153.2 18.1 63.1 51.0 32.5 33.8 52.8 51.7 35.6 188.3 45.9 67.1 22.6 165.4 284.0 50.1 26.4 44.4 30.8 33.6 31.5 39.0 73.5 80.3 39.5 34.8 32.0 51.4 20.7 38.8 49.2 26.3 23.1 50.0 25.2 29.9 SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 491.5;tongue: 580.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.5;Proximal tubular cells: 449.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" NA NA 7900 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favorable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" 85.8 95.7 68.0 59.0 72.2 94.6 68.7 80.6 84.3 56.8 81.1 134.3 163.0 56.0 71.0 77.4 59.8 48.0 302.8 69.9 76.9 228.0 336.1 56.1 75.3 74.8 71.4 44.4 80.3 144.3 42.8 57.6 73.8 55.7 132.4 62.9 74.0 60.5 491.5 55.6 121.9 70.4 73.9 60.5 92.8 64.4 74.9 62.7 64.3 580.6 84.2 71.3 52.0 78.9 157.3 152.7 72.2 107.8 141.6 135.2 95.9 122.4 145.2 254.3 227.7 216.8 183.1 206.8 159.3 156.4 176.1 180.1 290.7 226.8 284.8 128.7 280.6 183.4 149.2 168.2 172.8 276.0 135.6 140.4 154.9 224.5 370.1 138.7 183.6 176.5 165.2 236.9 179.6 129.5 182.4 175.1 70.4 224.6 302.6 146.1 142.5 265.4 252.4 88.7 157.5 86.0 172.3 216.3 392.3 76.4 131.1 169.1 94.9 115.8 131.0 206.4 176.0 98.9 133.3 198.6 170.4 438.5 128.3 68.7 149.8 149.5 71.4 206.5 70.7 89.9 81.0 77.5 186.8 81.1 73.5 74.8 174.3 85.3 185.7 89.3 113.8 116.1 68.0 72.2 80.6 84.3 69.9 76.9 74.8 71.4 73.8 73.9 74.9 78.9 48.2 64.1 47.4 20.9 57.4 52.1 93.3 199.8 40.5 31.5 45.2 49.4 405.5 101.5 97.0 47.8 14.6 107.1 48.3 176.1 354.1 134.3 220.3 48.7 38.2 54.7 48.6 77.3 27.7 149.2 142.2 62.0 46.9 45.5 66.6 39.9 46.8 226.0 177.4 37.0 32.1 103.1 116.0 88.7 67.9 30.5 57.8 78.4 64.0 29.0 123.1 78.3 48.4 15.6 24.6 111.5 218.3 67.7 62.2 74.4 300.5 449.0 79.8 53.8 39.5 57.1 191.6 148.9 71.5 72.9 54.6 121.8 46.8 69.3 162.0 110.9 SDHD "cybS, PGL, PGL1" ENSG00000204370 "Succinate dehydrogenase complex subunit D" O14521 11 112086824-112120016 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 530.2;Proximal tubular cells: 449.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045727 Approved "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "HPA045727: AB_10963114" "unprognostic (9.13e-2)" "unprognostic (3.51e-2)" "unprognostic (4.47e-3)" "unprognostic (4.21e-2)" "unprognostic (1.93e-1)" "unprognostic (4.98e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-3)" "unprognostic (7.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.99e-10)" "unprognostic (5.14e-2)" "unprognostic (1.58e-2)" "unprognostic (1.56e-2)" "unprognostic (7.51e-2)" 117.5 95.7 60.0 84.5 63.1 72.9 102.6 68.6 76.3 92.5 65.1 185.2 208.1 88.2 96.7 126.7 92.6 85.6 254.7 60.1 65.4 319.9 391.8 79.3 131.7 63.4 62.5 91.6 77.8 152.4 37.0 95.0 63.2 87.9 190.8 37.4 112.6 100.9 354.7 64.3 175.6 98.1 64.7 85.1 101.1 34.1 63.7 102.5 136.8 449.6 124.8 117.9 76.4 68.2 84.0 67.3 58.1 89.4 212.0 170.7 97.3 97.5 147.6 106.8 132.2 244.8 222.1 155.5 288.4 131.0 156.1 203.5 175.4 139.8 129.8 129.9 92.4 142.8 51.9 140.1 165.6 222.4 107.5 189.6 160.2 110.5 189.1 124.6 153.0 109.6 156.0 208.7 135.0 95.2 143.9 215.0 77.4 333.8 211.6 126.2 145.8 294.4 221.6 175.2 83.5 55.8 135.3 194.8 107.0 81.8 198.9 164.2 108.0 103.8 132.3 114.7 95.0 59.1 73.2 270.7 58.8 297.0 100.5 233.7 293.3 208.8 158.4 390.1 173.1 235.2 170.8 168.8 308.7 198.1 204.3 191.8 257.5 207.9 322.9 151.7 189.9 348.9 60.0 63.1 68.6 76.3 60.1 65.4 63.4 62.5 63.2 64.7 63.7 68.2 104.3 80.1 51.1 12.4 78.0 81.6 102.2 262.2 83.6 12.2 61.0 78.4 216.5 120.1 108.1 90.1 8.4 154.3 55.2 203.8 530.2 82.9 9.9 41.6 67.6 76.4 50.4 70.2 9.6 58.9 124.1 104.6 75.4 41.2 65.9 32.3 76.8 169.7 162.9 11.8 11.2 129.1 154.6 97.1 74.4 37.0 104.1 94.2 76.5 9.4 118.6 52.9 75.2 8.0 9.7 54.1 134.2 99.6 80.9 61.6 253.1 449.9 60.5 18.9 92.1 78.3 110.7 70.4 55.8 127.1 74.4 179.0 71.4 86.2 176.0 98.6 SDR9C7 "RDHS, SDR-O" ENSG00000170426 "Short chain dehydrogenase/reductase family 9C member 7" Q8NEX9 12 56923133-56934408 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 14.5;skin 1: 58.5;vagina: 21.3" "Group enriched" "Detected in some" 5 "Early spermatids: 1.2;Suprabasal keratinocytes: 4.0" "Group enriched" "Detected in some" 6 "cervical cancer: 3.0;head and neck cancer: 11.0;melanoma: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (6.75e-2)" "unprognostic (1.42e-1)" "unprognostic (7.90e-5)" "unprognostic (7.93e-2)" "unprognostic (4.20e-3)" "unprognostic (1.26e-1)" "unprognostic (4.74e-2)" "unprognostic (9.31e-2)" "unprognostic (3.78e-2)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (3.27e-1)" "unprognostic (1.74e-3)" 0.1 0.0 0.1 0.0 0.1 0.0 2.6 0.2 0.3 11.3 0.0 0.3 0.0 0.4 0.0 14.5 0.2 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.1 0.0 0.8 58.5 0.1 0.0 0.0 0.2 0.1 0.8 0.0 0.5 0.0 0.0 7.5 0.2 21.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.0 0.0 0.0 0.0 0.0 0.0 SEC23A ENSG00000100934 "Sec23 homolog A, COPII coat complex component" Q15436 14 39031919-39109646 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 347.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043806, HPA069974" Uncertain Approved Nucleoplasm,Vesicles NA NA 83000 "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA043806: , HPA069974: AB_2686223" "unprognostic (2.40e-1)" "prognostic unfavorable (5.75e-4)" "prognostic favorable (3.56e-4)" "unprognostic (3.30e-2)" "unprognostic (1.18e-1)" "unprognostic (6.39e-2)" "unprognostic (1.15e-2)" "unprognostic (5.85e-2)" "unprognostic (1.71e-1)" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (1.69e-4)" "prognostic unfavorable (2.94e-4)" "unprognostic (1.16e-1)" "unprognostic (2.73e-1)" "unprognostic (1.41e-3)" 45.9 32.0 11.4 31.8 14.2 13.1 20.9 18.3 16.8 36.2 31.4 40.0 57.7 42.7 19.9 34.1 21.5 32.1 46.9 13.3 18.9 23.1 80.8 20.2 21.0 13.8 14.0 33.9 12.0 8.1 10.5 27.1 15.3 34.0 34.2 38.5 10.5 52.6 54.2 12.8 52.6 90.5 7.6 20.5 16.8 23.5 12.7 18.9 17.9 58.5 22.0 40.7 17.9 15.4 52.1 90.8 76.9 74.7 161.3 173.0 25.9 195.1 176.4 135.2 166.8 93.2 44.2 12.6 46.9 279.6 54.9 41.2 99.6 86.3 208.6 39.6 36.9 21.8 67.7 347.3 122.4 35.9 31.3 134.0 48.8 91.6 73.7 114.6 130.8 26.9 15.6 30.1 125.8 47.5 32.9 16.9 18.4 81.7 91.3 44.0 111.8 19.1 84.7 75.6 8.5 20.5 132.8 43.0 51.8 68.6 51.5 12.4 138.4 75.0 57.8 110.8 52.0 27.0 36.6 56.0 50.3 31.4 70.2 70.5 34.3 38.6 26.6 29.3 38.4 23.6 33.1 34.9 31.1 21.1 34.9 28.0 29.5 42.1 27.3 26.7 38.1 31.4 11.4 14.2 18.3 16.8 13.3 18.9 13.8 14.0 15.3 7.6 12.7 15.4 35.4 16.0 26.9 34.9 30.5 25.9 33.5 15.5 15.4 39.7 11.8 10.3 54.6 15.7 18.8 31.3 68.8 16.0 36.0 87.0 7.9 9.8 13.4 11.3 42.8 41.1 24.5 6.1 48.3 5.6 43.7 55.0 26.5 18.8 27.9 56.9 118.9 133.6 25.6 30.3 51.1 31.6 12.2 36.4 32.3 18.6 74.9 24.3 24.9 48.7 25.6 19.4 32.0 34.2 44.3 17.8 34.1 71.5 38.5 37.5 88.6 32.8 10.1 58.7 39.5 27.6 51.4 18.0 15.5 15.7 24.0 24.8 32.3 31.0 30.2 56.5 SEC23B "CDA-II, CDAII, CDAN2, HEMPAS" ENSG00000101310 "SEC23 homolog B, COPII coat complex component" Q15437 20 18507520-18561415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008216, HPA069974" Uncertain Supported Vesicles NA Yes 16000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA008216: AB_1079895, HPA069974: AB_2686223" "unprognostic (4.47e-2)" "unprognostic (2.67e-2)" "unprognostic (3.52e-1)" "prognostic favorable (8.25e-4)" "unprognostic (1.24e-1)" "unprognostic (1.33e-1)" "unprognostic (5.44e-3)" "unprognostic (6.01e-2)" "unprognostic (1.39e-1)" "unprognostic (8.75e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-2)" "unprognostic (3.91e-2)" "unprognostic (1.72e-2)" "unprognostic (4.26e-2)" "unprognostic (2.81e-2)" "unprognostic (8.21e-2)" 19.6 38.3 18.7 32.0 27.1 36.0 37.8 24.7 25.9 36.2 27.4 31.6 23.8 17.2 53.8 28.4 29.5 23.1 8.5 19.5 22.4 37.4 30.6 29.7 30.5 27.2 23.8 16.9 57.1 50.6 32.6 24.2 27.2 34.8 32.7 40.7 70.9 35.9 4.1 18.2 23.3 18.5 24.5 25.5 38.2 34.8 23.2 27.6 59.5 6.2 38.0 30.5 12.6 38.9 85.0 93.9 49.8 48.7 32.3 36.6 116.0 69.8 45.3 80.0 68.7 84.9 73.8 37.5 44.9 50.4 107.0 88.5 88.5 120.7 86.2 47.5 43.1 64.9 35.6 130.6 70.5 90.2 78.7 28.0 71.8 118.0 151.4 47.6 50.6 34.0 74.8 82.4 55.1 90.7 59.8 49.5 48.0 118.9 101.6 62.4 77.7 122.1 83.0 85.6 78.8 58.0 83.6 188.9 80.6 62.6 82.3 94.4 45.3 53.1 29.8 58.4 87.1 104.2 155.9 60.1 45.3 47.8 74.4 147.9 94.1 106.0 57.2 95.6 78.7 67.2 56.8 61.4 107.9 61.2 51.3 54.0 48.0 78.8 94.9 80.7 75.4 103.7 18.7 27.1 24.7 25.9 19.5 22.4 27.2 23.8 27.2 24.5 23.2 38.9 8.5 16.0 43.5 15.3 24.7 11.5 21.0 34.3 10.2 21.0 21.5 15.6 3.0 20.0 42.5 31.3 16.7 34.3 36.0 26.2 58.7 36.1 95.6 25.4 12.4 11.3 19.7 7.4 17.9 33.4 30.0 11.7 25.0 31.3 15.9 13.6 11.0 25.6 42.9 13.5 20.5 34.7 26.4 38.7 21.0 11.3 14.3 30.3 23.2 15.0 33.1 23.9 9.2 23.1 27.0 31.8 24.2 10.5 59.0 30.1 11.8 53.2 45.4 20.4 19.7 12.4 12.2 48.7 22.1 15.8 14.2 65.8 21.0 16.0 21.5 28.3 SEC24D KIAA0755 ENSG00000150961 "SEC24 homolog D, COPII coat complex component" O94855 4 118722823-118838683 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Craniosynostosis, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 118.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041626, HPA053486" Approved Approved Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA041626: AB_10796348, HPA053486: AB_2682166" "unprognostic (9.06e-2)" "unprognostic (3.11e-1)" "unprognostic (3.23e-2)" "unprognostic (8.60e-3)" "unprognostic (1.05e-1)" "unprognostic (1.92e-1)" "unprognostic (1.93e-1)" "unprognostic (2.58e-1)" "unprognostic (9.39e-2)" "unprognostic (3.23e-1)" "unprognostic (1.22e-1)" "unprognostic (6.85e-2)" "prognostic unfavorable (3.42e-6)" "unprognostic (1.09e-3)" "unprognostic (5.64e-2)" "unprognostic (4.30e-3)" "unprognostic (1.37e-1)" 21.1 13.3 2.7 27.2 3.3 17.6 19.4 1.1 4.4 49.0 4.5 24.4 37.5 26.4 36.9 12.4 20.7 31.9 20.1 5.5 4.6 9.5 52.0 22.9 18.4 1.3 2.3 15.3 35.8 10.2 23.3 36.8 1.6 22.0 32.3 1.6 22.9 26.4 5.8 9.9 40.8 41.3 0.6 18.0 29.6 18.4 2.8 14.6 35.6 6.1 21.9 28.9 16.7 2.6 29.6 15.4 35.3 28.6 98.0 130.2 24.8 124.5 136.8 62.1 73.5 16.9 21.3 23.2 17.3 198.7 32.1 10.0 19.4 39.2 66.8 19.4 10.5 25.7 22.8 70.6 99.8 68.6 46.0 77.9 21.6 54.9 89.2 110.3 103.9 15.8 6.7 69.1 98.5 20.6 33.2 20.4 33.3 66.5 24.8 20.1 25.8 41.2 55.6 14.7 20.9 41.8 17.8 89.1 15.3 50.9 12.6 53.9 113.9 48.0 15.3 69.7 28.6 53.1 21.1 38.6 104.5 42.8 68.5 5.8 5.6 16.3 3.1 6.0 6.3 1.7 3.2 4.4 5.8 1.5 2.1 2.7 4.8 5.0 7.4 2.9 4.7 2.6 2.7 3.3 1.1 4.4 5.5 4.6 1.3 2.3 1.6 0.6 2.8 2.6 13.0 3.2 15.3 4.9 19.4 21.0 15.2 19.4 25.6 4.5 19.0 10.2 5.9 17.2 25.5 14.7 0.0 24.3 24.2 18.2 0.0 10.3 101.3 17.4 61.3 23.2 41.3 6.1 57.4 25.3 54.2 49.7 37.2 39.4 8.2 14.2 21.8 70.0 28.1 1.7 6.5 81.0 12.2 34.0 54.4 84.6 45.7 25.1 17.8 48.7 18.3 1.3 13.4 37.7 3.7 13.0 13.6 38.4 118.8 30.7 48.1 4.2 23.0 2.9 26.3 17.5 38.7 14.5 9.7 10.4 17.6 45.0 16.3 34.2 19.1 40.1 SEC31A "ABP125, ABP130, KIAA0905, SEC31L1" ENSG00000138674 "SEC31 homolog A, COPII coat complex component" O94979 4 82818509-82901166 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005457 Approved Supported Vesicles,Cytosol NA NA 40000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cytosol" "HPA005457: AB_1079896" "unprognostic (3.50e-2)" "unprognostic (2.28e-3)" "unprognostic (2.55e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-1)" "unprognostic (6.52e-2)" "prognostic unfavorable (3.32e-4)" "unprognostic (6.14e-3)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "unprognostic (4.21e-3)" "unprognostic (3.62e-1)" "unprognostic (1.64e-1)" "unprognostic (5.53e-3)" "unprognostic (2.92e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.69e-4)" 98.7 103.3 52.2 78.4 54.3 119.4 111.4 62.4 70.1 145.5 94.9 107.1 124.2 119.7 162.1 92.6 90.9 122.1 110.7 54.0 61.4 133.6 174.8 96.2 88.2 58.4 58.7 152.8 192.6 116.4 108.4 143.2 58.7 113.4 127.2 87.9 134.0 111.3 96.8 107.8 111.0 131.5 50.9 76.5 110.1 77.8 54.4 93.8 168.0 85.6 102.1 113.1 94.1 63.9 146.2 65.2 183.6 130.4 318.9 394.5 133.3 264.8 295.4 146.0 179.2 113.2 182.3 188.3 113.7 532.2 84.6 68.1 183.3 176.2 200.4 193.4 72.7 115.3 110.5 302.1 316.4 124.4 140.7 380.5 217.7 223.5 254.3 251.2 240.5 83.8 178.4 181.1 264.2 128.6 164.9 99.6 126.1 154.0 58.3 121.2 100.1 140.3 237.2 83.0 118.6 131.2 105.7 180.7 174.9 184.8 142.1 137.8 248.2 190.7 98.9 169.0 168.8 135.1 62.4 256.7 190.6 147.8 224.2 84.3 66.9 51.2 65.1 74.0 80.5 60.0 57.6 64.3 73.3 50.0 56.9 54.6 19.2 89.9 83.1 61.1 52.7 71.8 52.2 54.3 62.4 70.1 54.0 61.4 58.4 58.7 58.7 50.9 54.4 63.9 62.6 105.8 85.3 50.9 58.1 60.5 60.5 64.1 56.9 52.3 54.5 43.7 85.5 51.5 109.8 47.8 54.2 57.3 61.0 62.8 27.4 65.8 30.6 90.1 164.6 65.0 38.3 41.2 61.0 71.2 85.3 125.2 100.9 119.7 75.2 241.0 65.0 94.0 45.9 42.1 60.0 99.4 50.8 51.2 55.3 19.3 139.1 63.8 51.6 67.5 60.4 36.5 38.1 74.9 72.6 67.5 46.3 126.0 152.2 76.3 121.0 65.9 100.5 66.9 52.6 86.5 98.9 30.3 34.6 62.2 74.2 81.5 55.4 78.9 54.9 101.1 SEC63 "DNAJC23, ERdj2, PRO2507, SEC63L" ENSG00000025796 "SEC63 homolog, protein translocation regulator" Q9UGP8 6 107867756-107958208 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 354.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053295, HPA060535" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA053295: AB_2682105, HPA060535: AB_2684312" "prognostic unfavorable (3.32e-4)" "prognostic unfavorable (4.01e-4)" "unprognostic (4.08e-1)" "unprognostic (1.56e-1)" "unprognostic (4.36e-3)" "unprognostic (1.51e-2)" "unprognostic (8.33e-3)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" "unprognostic (1.04e-1)" "unprognostic (3.27e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (6.16e-4)" "unprognostic (2.35e-1)" "unprognostic (1.93e-1)" "unprognostic (1.56e-1)" "unprognostic (4.41e-2)" 27.5 33.0 11.6 22.0 14.3 32.9 23.3 14.4 12.9 30.2 25.7 19.2 16.8 25.2 29.6 19.5 21.8 22.0 19.0 12.4 15.3 20.0 46.6 21.7 16.7 13.3 12.0 40.4 61.2 31.7 14.4 20.9 14.2 27.7 18.6 21.2 77.8 23.3 14.3 15.5 18.0 22.2 12.3 16.1 23.1 33.0 12.1 22.6 52.1 14.1 17.3 21.8 14.0 17.7 28.5 17.1 46.0 57.6 47.1 55.2 41.4 59.2 65.0 27.8 39.2 30.8 34.6 52.8 49.4 53.7 34.4 40.9 32.3 38.3 42.5 63.8 35.7 57.2 25.2 31.6 73.2 65.9 32.5 43.5 61.4 44.5 97.6 50.0 39.3 31.7 48.5 82.8 57.7 22.7 20.6 29.5 36.4 30.0 18.1 65.2 54.4 43.7 33.5 37.1 40.3 45.7 32.9 48.8 59.1 31.2 34.9 95.8 42.5 41.6 25.8 42.2 46.6 31.4 25.0 52.9 45.9 56.4 48.7 5.6 5.2 5.0 4.8 4.7 7.5 4.4 3.9 3.9 5.4 4.0 4.3 3.4 1.7 7.1 9.8 6.9 2.2 3.5 11.6 14.3 14.4 12.9 12.4 15.3 13.3 12.0 14.2 12.3 12.1 17.7 55.6 118.6 143.3 38.2 64.4 85.0 70.5 90.9 42.7 57.7 67.8 54.2 78.8 81.5 125.5 53.3 39.6 80.8 71.6 39.2 11.7 86.0 40.3 48.7 102.8 61.6 53.5 31.5 52.5 125.4 96.4 107.1 46.9 54.8 68.9 84.8 59.6 126.7 62.7 47.1 50.8 80.0 83.4 56.7 78.9 23.9 106.2 54.8 80.0 42.2 54.3 61.0 59.8 60.3 64.8 81.9 53.5 118.8 144.6 91.1 37.2 38.4 116.7 49.9 46.0 108.2 77.2 143.1 75.0 44.7 80.0 91.0 52.3 354.8 60.8 73.8 SEMA3E "coll-5, KIAA0331, M-SemaK, SEMAH" ENSG00000170381 "Semaphorin 3E" O15041 7 83363238-83649139 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.3;Alveolar cells type 2: 110.2;Bipolar cells: 75.7;Excitatory neurons: 84.9;Oligodendrocyte precursor cells: 250.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 3.9;SK-BR-3: 19.9;U-2 OS: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029419, HPA063804" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA029419: AB_10602090, HPA063804: AB_2685127" "unprognostic (4.42e-2)" "unprognostic (1.48e-2)" "unprognostic (7.82e-2)" "unprognostic (4.42e-2)" "unprognostic (2.60e-1)" "unprognostic (4.27e-2)" "unprognostic (9.36e-2)" "unprognostic (4.09e-2)" "unprognostic (3.25e-1)" "unprognostic (1.42e-1)" "unprognostic (9.09e-2)" "unprognostic (2.60e-1)" "unprognostic (1.46e-6)" "unprognostic (1.32e-2)" "unprognostic (1.14e-1)" "unprognostic (7.17e-3)" "unprognostic (2.62e-1)" 1.2 0.1 3.1 0.2 2.8 0.0 2.8 0.6 2.3 1.8 0.1 2.1 0.6 1.9 0.3 1.2 0.6 2.3 0.1 5.0 5.3 0.1 0.1 2.2 0.0 1.6 4.3 0.1 0.4 0.0 0.2 0.2 1.3 4.3 1.7 3.9 2.2 3.3 0.2 0.5 1.2 1.1 3.2 0.0 1.3 0.0 4.3 1.7 0.6 1.0 0.1 3.2 0.7 3.7 0.2 1.1 0.2 0.0 0.5 3.1 0.0 0.0 0.2 0.2 0.3 0.0 0.3 0.0 0.0 0.0 0.5 0.0 3.4 0.0 1.3 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.9 0.0 0.0 0.5 0.4 1.1 0.0 2.0 0.0 0.0 0.8 0.1 0.0 0.0 19.9 0.0 3.2 1.6 0.0 0.0 0.7 6.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 2.8 0.6 2.3 5.0 5.3 1.6 4.3 1.3 3.2 4.3 3.7 10.5 176.3 110.2 2.9 0.2 1.1 1.3 1.6 0.0 75.7 19.0 7.5 1.7 18.6 43.2 1.8 0.0 0.8 0.2 0.1 0.0 3.9 1.1 3.8 1.2 10.7 0.0 0.0 84.9 1.1 0.4 21.3 3.1 9.3 24.0 0.2 0.0 0.3 0.1 0.0 12.3 0.0 4.1 1.0 2.1 0.0 0.9 3.6 1.8 1.0 1.0 29.6 0.0 250.3 6.0 6.2 0.0 0.0 0.3 2.6 0.1 0.5 35.7 3.6 0.0 0.8 1.0 0.3 0.6 0.3 0.4 0.3 2.8 0.0 0.0 2.5 SEPSECS "SLA, SLA/LP" ENSG00000109618 "Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase" Q9HD40 4 25120014-25160550 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "RNA-binding, Transferase, tRNA-binding" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 26.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070409 Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA070409: AB_2686265" "unprognostic (1.83e-1)" "unprognostic (4.09e-2)" "unprognostic (6.37e-3)" "unprognostic (5.86e-2)" "unprognostic (9.63e-2)" "unprognostic (4.61e-3)" "unprognostic (1.82e-3)" "unprognostic (6.33e-2)" "unprognostic (1.24e-1)" "unprognostic (3.34e-1)" "unprognostic (2.52e-1)" "unprognostic (3.56e-2)" "unprognostic (4.45e-3)" "unprognostic (4.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (2.13e-3)" 4.7 3.5 2.1 1.7 2.1 0.7 4.4 2.0 3.0 4.2 1.6 5.3 4.8 3.8 2.6 3.2 3.8 2.5 2.7 2.0 2.1 8.2 26.1 3.9 2.1 2.2 2.0 4.9 7.4 3.3 3.0 2.8 2.1 3.4 2.7 1.5 3.9 2.0 3.4 5.2 7.6 1.3 2.0 5.6 5.0 4.0 2.1 5.2 4.8 2.6 2.0 3.8 3.5 2.3 1.7 1.0 3.0 1.3 3.9 4.9 2.5 1.1 1.9 2.6 2.3 0.6 2.6 2.9 1.4 1.0 2.6 1.3 3.5 1.2 2.0 1.9 1.3 2.5 1.0 1.8 4.0 2.0 3.3 4.0 4.2 1.0 3.7 3.1 2.5 4.3 7.0 2.5 1.6 0.7 4.4 6.2 2.1 1.8 2.5 1.3 4.3 1.7 3.7 0.7 1.6 2.4 1.3 1.4 4.7 1.9 1.5 5.5 1.0 1.4 0.7 0.7 1.7 2.3 6.2 1.6 1.4 5.4 1.8 0.0 0.2 0.1 0.1 0.6 0.2 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 2.1 2.1 2.0 3.0 2.0 2.1 2.2 2.0 2.1 2.0 2.1 2.3 5.7 0.0 7.2 9.4 6.6 2.4 1.7 3.9 2.8 3.0 5.5 4.3 5.3 22.8 4.3 16.5 0.0 5.5 4.1 10.2 7.9 5.4 30.0 7.3 6.2 6.1 6.1 8.2 5.3 4.7 3.5 4.8 8.2 5.4 3.8 7.9 6.1 42.6 6.1 5.0 7.2 7.7 4.1 8.1 4.5 18.1 3.4 6.6 3.6 14.0 8.0 3.2 4.1 16.1 18.5 5.4 6.0 6.4 6.9 2.7 20.0 20.9 10.2 2.4 0.0 4.9 4.4 26.0 18.3 5.3 3.3 5.9 6.2 7.6 7.8 1.1 SERPINB7 MEGSIN ENSG00000166396 "Serpin family B member 7" O75635 18 63752935-63805376 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "lymphoid tissue: 38.4;skin 1: 129.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 79.5;Basal respiratory cells: 353.3;Club cells: 120.7;Ductal cells: 157.8;Extravillous trophoblasts: 82.2;Pancreatic endocrine cells: 276.5" "Cancer enhanced" "Detected in many" "cervical cancer: 8.0;head and neck cancer: 8.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 240.4;fHDF/TERT166: 170.8;HaCaT: 412.8;HBEC3-KT: 131.9;HBF TERT88: 223.0;hTERT-HME1: 130.9;U-138 MG: 219.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "cerebral cortex: 12.9;hippocampal formation: 11.4" HPA024200 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 160000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" Mitochondria "HPA024200: AB_1856730" "unprognostic (8.66e-3)" "unprognostic (6.31e-3)" "unprognostic (6.55e-2)" "unprognostic (4.03e-4)" "unprognostic (9.11e-2)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (9.99e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (2.02e-1)" "unprognostic (6.81e-2)" "unprognostic (1.62e-1)" "unprognostic (3.37e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-3)" 0.5 0.0 0.0 0.4 0.0 0.0 13.0 0.0 0.0 3.0 0.0 0.7 0.0 0.7 0.0 1.8 0.0 0.3 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.7 0.0 0.5 129.5 0.0 0.1 0.0 0.0 0.7 0.4 0.1 4.5 0.0 0.0 38.4 0.0 4.8 0.0 28.2 0.1 0.0 0.1 0.0 3.7 0.0 240.4 48.2 36.0 26.6 0.0 1.0 0.1 0.1 170.8 62.5 412.8 0.1 131.9 223.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 8.6 22.9 5.5 130.9 1.8 0.0 0.0 0.0 0.8 21.7 0.0 0.0 0.0 0.6 0.0 11.9 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.8 0.1 0.2 0.0 219.4 8.1 4.7 22.8 0.1 0.0 0.0 22.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 79.5 0.9 353.3 0.0 0.0 0.1 0.0 0.0 0.0 120.7 0.0 0.0 1.9 0.0 0.5 0.0 157.8 0.1 0.0 0.0 0.5 0.0 0.0 0.2 8.8 82.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.0 2.0 0.0 3.0 0.0 0.0 0.2 3.6 0.0 1.6 0.0 0.0 0.5 0.3 276.5 1.1 0.0 0.0 4.5 0.0 0.3 13.0 0.0 0.0 0.0 5.4 0.0 0.2 0.0 21.9 6.2 0.1 0.0 0.0 8.2 SERPINB8 "CAP2, PI8" ENSG00000166401 "Serpin family B member 8" P50452 18 63970029-64019779 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 58.8" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 120.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB034300 Enhanced Approved Nucleoplasm,Cytosol NA NA 920000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB034300: AB_2186486" "unprognostic (8.49e-2)" "unprognostic (4.87e-2)" "unprognostic (4.10e-3)" "unprognostic (2.86e-2)" "unprognostic (1.52e-2)" "unprognostic (7.71e-2)" "unprognostic (4.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.58e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (8.73e-2)" "unprognostic (3.48e-2)" "unprognostic (1.25e-1)" "unprognostic (1.90e-1)" 10.8 9.5 2.6 15.8 3.2 30.3 9.5 3.4 3.6 9.3 3.5 8.6 6.3 4.7 1.5 30.1 4.4 18.1 5.7 2.8 3.9 9.0 37.8 12.1 13.4 5.2 4.0 4.2 7.1 2.7 3.7 7.2 4.8 4.6 9.7 2.3 10.8 3.3 3.0 58.8 8.8 7.3 4.3 7.8 7.1 2.7 4.6 6.5 5.3 2.3 18.3 23.7 17.1 4.5 24.2 4.8 4.0 28.8 13.9 19.7 2.0 75.6 72.9 46.8 46.4 1.0 10.8 0.4 27.2 45.6 23.3 38.3 0.8 48.2 66.3 33.4 0.9 0.0 8.7 2.5 32.1 120.0 10.0 19.1 41.3 63.6 20.9 30.3 51.4 5.1 0.7 13.4 32.9 2.1 2.1 13.5 1.7 3.8 23.6 1.7 10.5 2.1 21.4 27.1 2.3 2.4 15.0 2.3 28.8 3.3 0.8 45.4 79.2 71.0 15.4 8.8 31.1 5.9 1.0 0.1 72.5 69.2 63.0 2.7 44.2 2.0 7.6 34.2 6.8 7.1 6.3 4.7 53.8 9.9 3.3 5.2 12.4 4.6 18.1 28.8 8.9 11.2 2.6 3.2 3.4 3.6 2.8 3.9 5.2 4.0 4.8 4.3 4.6 4.5 6.0 3.2 8.3 0.3 9.1 41.0 25.9 38.9 5.7 0.4 5.5 3.8 1.2 8.6 25.5 0.0 0.0 4.9 13.4 12.3 0.0 30.0 1.3 7.6 3.3 8.7 1.8 3.0 1.8 19.2 5.6 8.6 8.2 16.3 4.5 0.9 7.5 9.6 15.3 0.0 1.3 3.5 12.2 24.8 35.1 1.1 0.9 35.9 16.0 1.0 29.0 1.6 5.2 1.5 2.9 42.2 10.7 0.0 3.5 13.0 8.5 2.9 12.9 0.3 0.0 12.3 9.8 1.7 2.3 18.2 48.4 31.3 8.2 1.4 5.0 33.3 SERPINF1 "EPC-1, PEDF, PIG35" ENSG00000132386 "Serpin family F member 1" P36955 17 1762029-1777565 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1875.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 697.8;Cytotrophoblasts: 795.6;Fibroblasts: 951.9;Hepatocytes: 765.0;Leydig cells: 1818.0;Peritubular cells: 1045.7" "Cancer enhanced" "Detected in all" "liver cancer: 245.2" "Region enhanced" "Detected in many" "hippocampal formation: 85.4" "Immune cell enriched" "Detected in many" 18 "plasmacytoid DC: 1454.4" "Lineage enriched" "Detected in all" 121 "dendritic cells: 1454.4" "Group enriched" "Detected in many" 4 "ASC diff: 1232.0;ASC TERT1: 956.3;Hep G2: 606.0;HHSteC: 410.6;HSkMC: 1313.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005825 Uncertain "Secreted to blood" NA NA 9290000000 44000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA005825: AB_1079921" "unprognostic (3.85e-1)" "prognostic favorable (5.49e-4)" "unprognostic (9.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.32e-3)" "unprognostic (2.33e-1)" "unprognostic (7.88e-2)" "unprognostic (5.92e-2)" "unprognostic (1.69e-1)" "unprognostic (4.18e-2)" "prognostic unfavorable (1.40e-8)" "unprognostic (2.11e-3)" "unprognostic (2.82e-1)" "unprognostic (4.53e-3)" "unprognostic (1.25e-3)" 535.5 57.5 5.7 124.2 9.6 11.9 490.2 17.9 28.0 558.7 1875.2 131.3 41.9 358.2 90.2 109.3 557.4 559.7 376.5 85.4 1.1 35.1 974.8 158.9 133.5 0.1 5.1 408.3 207.6 11.2 62.4 311.6 1.3 202.8 52.0 61.4 124.6 105.8 434.8 162.9 131.7 221.7 2.8 133.2 124.7 277.7 25.4 106.2 193.1 465.5 117.7 323.4 273.5 7.0 0.5 3.7 2.8 2.0 1232.0 956.3 20.4 56.8 49.8 0.6 0.0 9.7 0.5 2.3 1.9 71.8 0.3 3.2 86.0 4.4 0.0 0.6 46.0 1.0 1.2 606.0 410.6 1.1 1.1 1313.4 6.9 0.9 1.1 11.4 0.6 4.2 117.5 0.4 63.2 0.2 7.0 7.2 30.7 0.3 1.0 2.9 219.9 1.6 0.1 6.0 1.9 42.2 0.7 0.7 57.0 3.4 6.7 184.2 2.0 0.5 17.6 14.1 1.2 0.7 2.4 28.1 1.7 0.6 0.8 0.1 12.0 1.1 0.6 4.4 0.4 9.0 0.7 0.9 79.8 5.2 2.0 5.5 1.7 1.3 0.2 1454.4 0.8 14.2 5.7 9.6 17.9 28.0 85.4 1.1 0.1 5.1 1.3 2.8 25.4 7.0 59.0 3.2 10.4 0.3 10.8 95.0 238.0 697.8 27.9 59.3 6.7 71.2 12.1 11.5 167.7 1.8 223.1 795.6 226.1 0.0 0.0 0.3 11.2 12.5 372.4 26.2 0.0 19.2 5.3 24.5 98.7 951.9 11.2 6.7 22.9 1.7 28.2 765.0 151.6 3.3 2.6 0.0 366.2 60.4 262.6 53.0 1818.0 79.0 108.5 9.4 79.0 11.6 1.0 0.5 2.0 6.8 0.1 1045.7 7.0 155.5 0.2 27.3 105.5 39.1 19.7 193.3 202.8 12.7 8.7 4.5 78.6 534.8 14.3 10.2 0.3 47.7 SERPINH1 "CBP1, CBP2, colligen, HSP47, SERPINH2" ENSG00000149257 "Serpin family H member 1" P50454 11 75562056-75572783 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 473.6;Endometrial stromal cells: 273.3;Extravillous trophoblasts: 342.1;Fibroblasts: 287.6;Smooth muscle cells: 295.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 291.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 1018.3;fHDF/TERT166: 1215.2;HHSteC: 1029.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004441, HPA029198" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA Yes 920000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004441: AB_627757, HPA029198: AB_10601712" "unprognostic (3.80e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (5.93e-2)" "unprognostic (2.81e-3)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.39e-2)" "unprognostic (1.72e-3)" "unprognostic (2.35e-2)" "unprognostic (7.40e-2)" "unprognostic (1.57e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.22e-15)" "unprognostic (2.75e-2)" "unprognostic (1.27e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" 214.1 101.9 46.2 106.5 50.4 3.7 107.1 51.1 291.0 137.7 66.7 95.2 23.2 160.7 27.6 41.7 119.4 72.1 159.3 46.1 50.5 116.9 52.5 199.3 21.1 59.9 47.3 157.4 40.1 18.1 50.8 251.3 58.3 66.1 36.7 2.0 40.7 53.2 22.2 47.6 51.3 207.3 51.6 53.9 76.9 27.7 54.0 21.6 91.2 33.2 18.2 156.8 85.9 60.1 57.7 192.9 349.5 722.0 528.8 484.2 162.2 514.3 349.6 380.4 483.5 1018.3 294.1 0.4 470.2 1215.2 3.1 337.2 242.2 163.2 182.5 27.5 47.0 42.7 174.0 216.5 1029.5 0.9 7.2 580.9 165.2 365.0 121.3 475.5 530.8 22.1 90.5 16.1 182.5 457.6 1.2 74.8 315.6 215.8 50.7 29.3 200.3 48.8 95.6 107.8 9.1 119.1 326.9 59.7 102.0 539.6 144.4 72.7 284.6 388.6 324.6 270.6 128.3 23.1 25.5 6.1 168.0 0.2 535.6 4.1 1.1 0.1 6.0 1.1 5.2 0.9 3.9 4.0 4.4 0.7 4.0 3.3 0.2 5.9 0.1 3.7 3.5 2.1 46.2 50.4 51.1 291.0 46.1 50.5 59.9 47.3 58.3 51.6 54.0 60.1 142.3 38.5 32.0 4.9 2.9 81.8 473.6 56.5 74.0 5.3 28.3 39.5 36.6 14.3 21.0 25.8 58.4 217.0 3.2 33.0 0.0 64.5 2.9 21.8 273.3 194.9 61.1 11.4 0.4 11.9 342.1 287.6 15.3 33.0 9.5 144.1 124.9 9.9 94.2 6.7 0.2 55.7 22.4 5.7 110.0 6.0 164.4 43.6 44.4 18.7 9.8 14.3 8.2 1.0 0.5 22.5 24.3 120.7 6.5 139.8 12.4 22.8 11.9 1.2 92.1 31.4 295.1 29.3 23.0 14.1 44.5 165.8 68.8 79.8 62.8 73.4 SETBP1 "KIAA0437, SEB" ENSG00000152217 "SET binding protein 1" Q9Y6X0 18 44680173-45068510 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 349.0;Inhibitory neurons: 548.3;Oligodendrocyte precursor cells: 170.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 11.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.0;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 5 "B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0" "Cell line enhanced" "Detected in many" "AF22: 16.1;Karpas-707: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049022, HPA057259" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 66000 "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA049022: AB_2680602, HPA057259: AB_2683384" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (4.63e-2)" "unprognostic (1.80e-1)" "unprognostic (1.91e-1)" "unprognostic (3.57e-2)" "unprognostic (3.49e-1)" "unprognostic (2.01e-2)" "unprognostic (2.71e-3)" "unprognostic (6.52e-2)" "prognostic favorable (6.34e-8)" "unprognostic (2.18e-2)" "unprognostic (2.29e-1)" "unprognostic (6.06e-2)" "unprognostic (7.81e-5)" 7.3 1.9 2.0 3.7 3.7 1.8 6.3 11.6 5.7 11.6 0.0 10.9 1.7 8.3 7.2 4.5 7.2 5.0 4.3 2.6 0.2 7.4 4.7 6.6 5.3 0.0 0.1 7.7 5.8 3.7 2.7 7.2 0.1 7.8 3.5 3.0 4.3 9.2 10.7 4.4 4.6 7.4 0.0 3.7 5.6 1.8 0.0 4.4 5.1 9.7 4.7 8.1 8.5 3.8 0.0 2.4 16.1 0.0 4.1 1.2 1.0 1.3 3.0 1.5 1.3 0.2 0.0 1.0 0.5 1.8 1.0 4.8 1.8 4.9 1.0 1.4 0.8 0.0 1.8 1.2 0.0 0.0 0.0 3.8 2.0 0.0 3.0 2.7 0.5 0.0 0.1 44.7 0.4 0.8 0.0 0.1 2.0 0.0 1.1 5.6 0.0 5.5 4.9 3.9 8.2 4.2 0.0 0.0 0.9 7.1 2.2 0.0 0.0 9.5 3.3 0.0 7.7 8.6 0.5 0.0 5.8 0.2 5.5 0.1 0.0 0.0 0.4 0.6 0.0 2.0 0.0 0.2 0.0 3.0 0.0 0.1 0.0 0.0 1.0 2.8 0.0 0.1 2.0 3.7 11.6 5.7 2.6 0.2 0.0 0.1 0.1 0.0 0.0 3.8 7.6 0.0 1.8 85.5 42.4 15.4 8.6 8.3 7.4 12.5 11.0 12.6 3.9 14.3 4.2 16.5 18.8 1.5 25.5 1.6 3.9 4.5 1.3 12.9 15.6 8.3 12.0 0.8 349.0 3.5 1.4 29.3 4.1 14.8 0.0 0.7 17.9 16.5 2.0 3.3 548.3 4.4 10.2 2.4 8.7 3.7 62.7 4.6 3.6 88.1 1.5 10.7 6.2 170.4 62.9 3.7 9.1 39.9 29.6 8.1 0.4 10.5 5.8 18.2 6.6 18.4 28.6 0.3 0.8 4.0 15.2 0.8 5.9 0.1 4.7 1.5 SETD2 "FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A" ENSG00000181555 "SET domain containing 2, histone lysine methyltransferase" Q9BYW2 3 47016429-47164113 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Differentiation, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042451 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA042451: AB_10806239" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (6.08e-2)" "unprognostic (1.01e-1)" "unprognostic (3.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.40e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (6.19e-2)" "unprognostic (2.45e-1)" "unprognostic (7.84e-2)" "prognostic favorable (7.99e-6)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (8.79e-2)" "unprognostic (5.43e-2)" 9.9 6.5 8.2 10.7 10.5 23.8 10.3 24.1 8.3 12.6 10.8 9.7 9.1 13.3 6.1 9.8 11.0 8.5 7.2 6.2 6.7 10.8 10.0 9.4 13.5 8.3 8.5 15.3 13.3 16.2 2.2 11.4 8.4 10.2 11.0 10.6 9.6 9.7 11.1 9.0 10.3 11.9 8.1 11.4 10.7 13.1 7.9 19.2 15.5 14.5 13.3 9.8 4.0 12.8 21.1 13.2 25.4 14.5 15.3 18.9 11.3 17.9 17.0 20.8 19.9 15.4 13.8 43.5 11.6 25.5 20.0 12.4 29.5 17.6 27.6 27.5 12.2 47.3 24.8 12.4 11.7 34.1 26.5 15.2 17.3 20.7 24.6 15.3 20.1 22.8 29.9 16.6 17.8 9.5 26.7 8.5 20.6 9.4 15.4 17.5 25.6 23.2 12.4 26.6 10.9 17.6 29.5 11.8 12.0 17.2 12.9 27.5 26.7 24.6 18.1 21.5 29.9 22.0 25.4 43.7 14.2 19.6 14.6 1.3 1.2 2.9 2.0 1.1 1.1 2.2 1.2 1.6 1.4 2.5 1.7 1.6 3.3 3.6 1.1 1.5 0.6 0.6 8.2 10.5 24.1 8.3 6.2 6.7 8.3 8.5 8.4 8.1 7.9 12.8 50.5 48.1 58.8 115.9 58.3 33.3 22.6 15.6 54.1 40.5 31.0 29.1 67.2 27.1 53.2 11.0 41.7 20.3 58.2 32.6 11.7 20.9 26.1 62.8 63.0 41.2 22.1 38.9 131.4 22.4 12.7 39.2 56.6 66.2 58.8 68.9 23.6 29.8 16.8 26.9 129.4 28.2 14.2 28.8 26.5 35.1 30.4 42.7 17.8 148.9 37.9 22.7 43.3 113.1 143.2 23.7 22.3 33.1 54.0 31.2 24.6 11.5 49.7 39.9 13.1 56.1 42.6 71.0 29.3 60.2 35.7 18.5 65.3 57.1 29.5 34.7 SF3B4 "Hsh49, SAP49, SF3b49" ENSG00000143368 "Splicing factor 3b subunit 4" Q15427 1 149923317-149927803 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028578, HPA064660" Approved Approved "Nuclear speckles" NA NA 36000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA028578: AB_10601601, HPA064660: AB_2685314" "unprognostic (2.43e-1)" "unprognostic (6.58e-2)" "unprognostic (2.49e-2)" "unprognostic (9.26e-3)" "unprognostic (2.74e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (3.11e-1)" "unprognostic (2.04e-1)" "unprognostic (6.60e-2)" "unprognostic (2.12e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.74e-7)" "unprognostic (9.63e-2)" "unprognostic (6.54e-2)" "unprognostic (3.15e-2)" "unprognostic (1.91e-1)" 35.6 36.8 27.9 42.3 28.4 74.3 31.6 30.1 35.8 36.0 29.3 55.8 39.6 48.5 37.5 45.1 51.8 33.8 28.9 28.6 30.4 29.9 27.1 36.8 48.5 31.1 28.3 47.5 34.6 53.4 26.0 40.1 28.7 32.3 44.2 20.8 40.1 47.9 22.5 62.4 40.1 46.7 28.0 39.4 32.4 46.4 29.1 58.0 39.1 26.9 57.6 50.3 33.4 29.8 153.0 144.1 119.4 110.9 75.5 58.4 172.0 119.0 118.2 188.0 143.0 152.0 125.6 144.2 87.1 139.7 103.0 154.3 150.9 158.2 161.8 95.3 110.7 130.0 77.3 112.8 121.7 156.6 163.5 74.7 122.6 184.0 84.5 59.0 94.6 126.7 116.6 119.6 172.9 456.6 203.9 148.9 199.4 175.9 146.1 157.9 106.4 157.6 137.4 128.2 79.6 147.6 109.8 151.1 92.5 141.4 229.9 205.1 78.3 154.9 170.0 122.9 222.8 169.0 259.4 161.2 124.2 133.8 147.5 70.5 81.1 130.5 84.0 109.8 87.4 80.2 79.6 90.4 71.3 73.1 74.3 71.9 111.2 104.7 120.0 84.6 100.1 67.5 27.9 28.4 30.1 35.8 28.6 30.4 31.1 28.3 28.7 28.0 29.1 29.8 30.4 16.0 13.4 4.2 39.9 54.2 47.5 83.2 65.4 20.0 34.3 41.4 3.9 21.5 41.2 23.9 4.2 80.8 54.2 42.2 60.7 64.3 80.3 38.9 30.4 30.6 26.0 34.3 4.1 51.6 77.5 31.8 27.0 44.5 39.3 32.9 16.8 14.7 53.0 8.4 4.8 40.0 59.0 24.7 42.5 13.3 45.1 34.9 24.9 3.7 61.8 27.5 44.3 4.5 7.0 62.3 35.9 29.3 38.6 32.2 28.5 43.0 49.8 15.9 46.0 30.8 64.6 64.0 51.5 47.0 51.3 94.7 44.9 27.9 36.7 43.8 SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 472.1;Fibroblasts: 196.4;Granulosa cells: 102.8;Peritubular cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.0;HSkMC: 3.9;U-937: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 53.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" NA NA 2500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" 29.1 15.6 2.3 1.4 3.0 0.8 60.0 2.7 4.5 619.9 2.1 4.4 1.2 467.1 18.7 2.3 214.0 17.3 22.4 2.5 4.6 4.3 0.6 14.7 7.3 4.0 4.8 79.2 5.0 2.8 20.5 0.2 3.2 16.1 2.6 2.3 6.5 43.9 4.1 1.5 1.4 87.9 4.0 13.9 2.3 16.8 2.7 1.6 14.9 7.0 2.0 37.4 61.0 3.9 0.0 1.8 2.1 0.0 10.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 2.2 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 1.5 0.1 0.3 0.0 3.9 0.5 0.4 0.0 0.7 0.1 0.1 0.0 0.2 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.7 0.0 0.8 1.2 0.1 0.4 0.1 0.1 0.2 3.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 2.7 4.5 2.5 4.6 4.0 4.8 3.2 4.0 2.7 3.9 5.5 0.0 1.8 0.3 0.7 1.0 1.5 0.1 0.6 0.0 0.5 2.3 1.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 1.0 22.5 472.1 4.6 0.0 0.0 0.0 0.5 0.3 196.4 0.0 14.1 0.0 102.8 3.3 0.1 0.2 0.0 0.5 0.0 0.0 0.0 4.4 2.8 41.7 7.1 0.0 2.8 0.0 2.7 0.0 17.6 0.2 0.1 0.0 188.4 0.0 2.4 0.0 1.8 0.0 0.3 0.0 30.5 25.3 0.2 0.4 0.1 1.6 0.3 9.2 1.2 0.1 0.5 SH3PXD2B "FLJ20831, KIAA1295" ENSG00000174705 "SH3 and PX domains 2B" A1X283 5 172325000-172454525 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 91.1;Leydig cells: 39.7;Oligodendrocytes: 63.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 95.2;ASC TERT1: 79.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036471 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nucleoli fibrillar center" "HPA036471: AB_10670799" "unprognostic (3.32e-1)" "unprognostic (1.95e-2)" "unprognostic (4.84e-1)" "unprognostic (2.96e-1)" "unprognostic (1.84e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (5.38e-3)" "unprognostic (3.11e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.87e-2)" "unprognostic (1.57e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (8.45e-4)" 22.6 25.4 9.2 11.2 12.8 0.1 19.0 12.9 11.5 36.4 9.6 14.0 2.3 32.6 5.4 10.5 17.9 18.9 7.4 9.8 10.7 2.4 2.9 17.6 3.5 14.5 12.8 18.4 9.8 6.6 5.0 8.9 16.0 12.8 5.6 3.6 18.3 13.9 3.5 19.8 11.5 23.2 10.1 6.5 13.1 6.3 13.7 4.2 8.0 3.4 3.4 18.3 18.1 15.4 1.0 14.3 52.3 34.6 95.2 79.9 44.3 8.6 29.7 5.4 10.7 4.0 1.3 0.1 11.5 33.4 16.7 8.1 18.7 9.8 5.3 0.8 3.5 0.1 13.3 2.9 30.6 0.0 36.5 51.5 15.1 22.4 6.4 5.2 37.9 3.8 0.1 0.2 24.1 3.1 0.1 4.6 20.1 8.1 3.3 17.3 8.5 5.1 5.7 1.5 4.6 29.2 6.0 3.8 10.7 16.5 1.4 2.1 40.9 33.4 13.2 20.7 3.8 0.0 0.0 0.2 22.6 2.2 27.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 12.8 12.9 11.5 9.8 10.7 14.5 12.8 16.0 10.1 13.7 15.4 11.3 0.0 1.1 91.1 0.4 10.1 3.2 13.9 8.6 0.6 6.2 6.5 1.8 5.7 12.0 0.0 0.0 4.5 0.2 1.3 0.0 9.9 0.9 5.5 30.8 6.4 2.4 0.0 5.0 16.0 31.0 29.8 6.1 13.4 0.0 5.8 3.3 1.8 3.1 1.7 11.2 2.1 18.3 28.4 9.4 2.0 39.7 13.6 14.2 13.1 1.3 6.3 0.0 25.1 63.0 21.8 1.0 27.1 0.0 6.9 0.2 1.9 3.8 0.3 13.1 6.0 10.5 0.8 4.2 4.7 8.1 2.2 0.5 22.3 2.7 5.7 SHH "HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS" ENSG00000164690 "Sonic hedgehog signaling molecule" Q15465 7 155799980-155812463 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, Hydrolase, Protease" "Disease variant, Holoprosencephaly, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 13.6;stomach 1: 10.5;urinary bladder: 16.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 8.3;Cholangiocytes: 18.6;Collecting duct cells: 9.2;Gastric mucus-secreting cells: 9.7;Hepatocytes: 20.1;Intestinal goblet cells: 8.6;Pancreatic endocrine cells: 11.7;Urothelial cells: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 8.9;GAMG: 39.8;OE19: 10.2;RT4: 25.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA 5500000 "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (7.17e-2)" "unprognostic (7.68e-3)" "unprognostic (6.70e-2)" "prognostic favorable (8.62e-5)" "unprognostic (1.59e-1)" "unprognostic (2.50e-2)" "unprognostic (2.39e-3)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.16e-2)" "unprognostic (3.47e-1)" "unprognostic (1.56e-1)" "unprognostic (1.77e-3)" "unprognostic (2.86e-1)" "unprognostic (2.85e-1)" "unprognostic (3.43e-2)" "unprognostic (2.66e-2)" 0.0 8.7 1.3 0.3 1.2 0.0 0.0 1.6 1.2 4.4 0.3 1.3 1.4 0.4 3.0 0.0 0.1 3.8 0.0 0.8 6.2 3.3 13.6 1.7 0.0 3.3 1.6 0.0 0.2 0.0 0.1 0.0 4.6 1.2 1.0 0.3 0.0 1.2 0.0 0.1 1.4 0.0 1.0 0.0 10.5 0.1 2.6 0.0 0.0 0.0 0.0 16.2 0.3 1.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.2 0.0 8.9 0.0 39.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 10.2 4.0 0.0 0.0 0.0 2.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.3 1.2 1.6 1.2 0.8 6.2 3.3 1.6 4.6 1.0 2.6 1.6 0.0 3.2 7.8 0.0 0.0 0.0 8.3 0.0 0.0 1.5 0.0 0.0 0.7 18.6 1.3 9.2 0.0 0.0 0.0 3.7 0.0 1.2 4.7 5.4 0.5 0.2 0.0 0.0 0.1 0.8 0.2 0.1 9.7 7.6 0.0 0.0 0.4 20.1 0.0 0.0 0.4 8.6 0.0 0.6 0.0 1.7 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.7 0.5 0.4 0.1 1.3 2.5 6.6 0.0 0.1 0.0 0.0 0.1 2.7 0.2 0.0 0.0 0.0 0.0 0.0 3.0 8.3 SHOC2 "KIAA0862, SOC-2, SOC2, SUR-8, SUR8" ENSG00000108061 "SHOC2 leucine rich repeat scaffold protein" Q9UQ13 10 110919593-111013666 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009164, HPA048134" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "HPA009164: AB_1079960, HPA048134: " "unprognostic (1.39e-1)" "unprognostic (3.52e-2)" "unprognostic (4.23e-3)" "unprognostic (3.27e-2)" "unprognostic (1.82e-2)" "unprognostic (1.76e-2)" "unprognostic (6.09e-2)" "unprognostic (5.56e-2)" "unprognostic (1.59e-1)" "unprognostic (1.07e-1)" "unprognostic (4.33e-2)" "unprognostic (1.01e-1)" "unprognostic (3.70e-3)" "unprognostic (6.97e-3)" "unprognostic (8.35e-2)" "unprognostic (2.95e-2)" "unprognostic (1.67e-1)" 25.0 16.3 16.4 22.5 17.8 45.7 19.3 19.3 22.1 20.3 12.0 20.4 16.4 20.7 21.0 21.6 16.4 20.1 19.5 19.4 22.3 21.9 23.7 17.9 29.9 16.6 21.7 19.8 20.4 30.3 14.6 20.8 22.0 18.0 21.5 19.7 14.2 17.5 21.3 15.4 18.4 23.3 16.4 22.2 17.3 36.4 18.2 26.9 25.2 26.8 31.2 25.0 14.8 15.5 29.2 17.8 22.7 38.2 50.9 51.2 14.5 35.0 51.9 31.9 38.5 16.5 25.8 63.1 17.1 62.8 19.9 24.1 27.8 25.0 46.2 34.7 16.5 28.8 25.7 16.2 37.0 49.6 49.4 57.3 38.6 36.9 69.1 43.6 32.8 22.1 18.3 43.8 45.7 15.6 24.7 38.9 14.1 15.6 18.6 34.8 45.2 18.1 33.3 19.4 11.7 23.4 30.7 15.0 34.9 25.8 77.2 41.5 33.3 25.6 22.6 32.5 24.3 40.2 44.0 100.1 30.6 50.3 18.6 52.3 22.8 33.5 12.6 26.8 15.5 30.3 14.8 15.0 22.3 24.4 15.6 15.2 65.8 19.5 27.8 15.2 19.2 23.9 16.4 17.8 19.3 22.1 19.4 22.3 16.6 21.7 22.0 16.4 18.2 15.5 73.8 54.5 48.1 35.6 95.4 55.8 35.2 37.5 27.9 27.6 51.4 39.1 83.6 45.8 42.3 31.3 16.7 22.2 77.5 80.8 64.6 48.5 44.2 65.1 54.6 63.5 26.3 67.5 59.9 59.2 23.0 50.7 49.5 54.9 73.4 20.2 53.2 69.0 29.4 30.3 53.1 36.2 46.8 78.3 67.3 89.7 65.6 76.0 49.8 57.1 116.5 31.5 57.7 46.3 61.0 64.0 51.6 80.9 53.4 37.1 51.7 67.7 57.0 32.7 72.3 59.9 58.7 108.8 69.3 38.1 69.9 60.6 65.8 17.0 30.1 49.7 SHOX "GCFX, PHOG, SHOXY, SS" ENSG00000185960 "Short stature homeobox" O15266 X 624344-659411 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 7.6" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 2.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "midbrain: 7.6;pons: 7.5" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 4 "BJ: 18.5;BJ hTERT+: 8.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "midbrain: 2.7;thalamus: 3.8" "HPA035141, HPA060931" Enhanced Nucleoplasm,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA035141: AB_2674489, HPA060931: AB_2684388" "unprognostic (7.51e-3)" "unprognostic (1.99e-1)" "unprognostic (3.08e-2)" "unprognostic (2.23e-1)" "unprognostic (4.00e-1)" "unprognostic (6.82e-2)" "unprognostic (2.45e-2)" "unprognostic (2.34e-1)" "unprognostic (9.24e-2)" "unprognostic (9.95e-2)" "unprognostic (5.67e-6)" "unprognostic (1.99e-1)" "unprognostic (1.71e-1)" "unprognostic (9.14e-2)" "unprognostic (1.38e-1)" 0.7 0.4 0.2 0.3 0.3 0.9 0.2 1.4 0.6 0.0 0.0 0.2 0.6 0.1 0.3 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.1 0.3 1.2 7.6 0.1 0.3 0.2 0.0 0.1 7.5 0.3 0.2 0.4 0.6 0.0 1.2 0.4 0.4 0.1 0.1 0.7 0.2 0.1 1.4 0.0 0.3 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.1 0.1 0.2 0.1 3.0 18.5 8.4 2.7 2.9 0.3 0.2 0.2 0.1 0.4 0.7 0.2 0.2 0.0 0.9 0.1 0.1 0.1 1.4 0.1 0.1 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.8 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.0 0.2 0.2 0.0 0.2 0.2 0.0 0.1 0.1 0.1 0.2 0.5 0.0 0.0 0.2 0.1 0.1 0.1 0.8 0.0 0.2 0.1 0.1 0.0 2.9 0.6 0.6 0.4 0.3 0.4 0.5 0.3 0.3 0.1 0.7 0.4 0.5 1.7 0.7 0.6 0.6 0.3 0.3 0.2 0.3 1.4 0.6 0.2 0.2 1.2 7.6 7.5 0.1 1.4 1.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 463.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.7;HUVEC TERT2: 26.7;RH-30: 5.0;RPTEC TERT1: 5.5;TIME: 10.0;WM-115: 5.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" 8.1 1.8 9.8 1.9 20.0 1.2 5.4 17.1 12.4 3.3 0.9 1.8 1.1 3.6 1.6 2.7 2.2 3.0 7.8 8.9 12.6 5.3 0.9 13.3 0.9 23.8 17.6 1.3 0.9 1.9 2.0 9.0 21.8 2.2 1.4 1.3 2.0 1.8 3.6 1.7 1.5 4.1 13.8 1.0 1.3 0.6 17.3 0.6 3.3 5.0 1.0 3.5 2.3 30.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 6.7 0.9 0.0 0.6 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 0.0 5.5 2.5 0.1 0.0 0.0 0.8 1.5 3.6 0.1 0.1 10.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 0.2 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 20.0 17.1 12.4 8.9 12.6 23.8 17.6 21.8 13.8 17.3 30.7 45.0 25.6 18.6 3.3 0.0 3.6 2.0 1.9 2.2 0.3 1.0 1.5 4.2 0.0 2.0 5.5 0.0 0.6 0.2 1.1 3.9 0.7 0.1 2.8 5.4 46.5 3.0 0.0 1.1 0.2 3.0 3.0 0.0 2.9 3.8 2.3 30.7 0.9 0.5 0.0 1.1 2.8 0.0 2.4 2.7 0.6 1.2 0.6 0.0 51.5 0.0 3.6 0.0 126.7 463.4 2.3 1.0 1.2 0.0 1.2 0.3 3.5 2.5 0.6 0.0 2.5 2.6 0.0 1.0 2.0 3.1 0.3 0.6 3.0 3.2 1.6 SIK3 "FLJ12240, KIAA0999, L19, QSK" ENSG00000160584 "SIK family kinase 3" Q9Y2K2 11 116843402-117098437 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 375.5;Excitatory neurons: 384.4;Inhibitory neurons: 399.6;Oligodendrocyte precursor cells: 457.9;Oligodendrocytes: 1679.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045245, HPA048161" Enhanced Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA045245: AB_2679270, HPA048161: AB_2680293" "unprognostic (3.19e-2)" "unprognostic (3.31e-1)" "unprognostic (2.78e-2)" "unprognostic (8.21e-2)" "unprognostic (1.31e-1)" "unprognostic (2.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.46e-2)" "unprognostic (1.28e-3)" "unprognostic (1.89e-1)" "prognostic favorable (1.12e-5)" "unprognostic (1.82e-1)" "unprognostic (6.85e-2)" "unprognostic (1.02e-2)" "unprognostic (3.28e-2)" 10.1 7.2 19.3 11.4 36.6 12.7 9.2 15.0 34.3 9.6 0.0 11.7 8.5 12.6 7.2 10.4 12.4 9.8 12.8 19.7 19.4 10.3 13.8 9.7 9.9 22.0 23.1 16.5 15.4 17.7 10.0 12.1 22.5 8.2 8.8 19.1 9.8 11.3 19.5 7.5 8.7 14.1 11.5 11.8 9.7 21.4 36.1 12.3 17.1 14.4 10.4 10.1 7.5 41.1 11.8 8.9 13.9 14.7 11.7 12.6 22.2 8.8 15.7 6.8 7.6 21.8 13.3 13.9 14.0 16.3 15.0 18.1 11.6 12.7 9.4 38.5 7.4 31.2 9.7 13.6 10.9 11.2 11.8 13.9 7.2 14.5 23.3 8.7 9.2 9.0 15.2 10.1 9.4 4.0 10.2 12.1 7.7 8.0 6.6 12.9 8.0 11.1 9.3 2.2 13.5 10.8 23.7 10.3 4.4 10.5 6.8 11.8 10.6 8.3 10.4 14.0 8.9 7.1 5.6 17.5 7.7 18.2 11.4 2.0 0.4 0.0 0.3 0.5 0.5 0.1 0.3 0.1 0.6 1.0 0.0 0.0 0.9 0.6 1.5 0.0 0.0 0.2 19.3 36.6 15.0 34.3 19.7 19.4 22.0 23.1 22.5 11.5 36.1 41.1 25.8 9.6 22.1 375.5 34.9 26.5 26.0 6.8 7.4 42.6 26.1 21.5 22.2 10.0 12.4 5.5 112.6 8.7 47.3 12.5 5.9 7.6 89.2 64.4 27.9 20.4 17.3 12.4 384.4 7.3 2.8 22.1 12.8 71.5 17.2 37.4 17.2 26.3 7.7 47.1 399.6 11.1 6.1 21.7 45.1 214.9 10.2 31.4 16.0 161.1 25.6 36.3 12.3 457.9 1679.9 9.2 8.2 14.3 28.1 22.0 9.7 6.9 20.5 63.9 0.0 35.0 23.2 18.0 14.8 7.4 24.3 29.7 44.2 14.8 11.4 30.0 SIX1 DFNA23 ENSG00000126778 "SIX homeobox 1" Q15475 14 60643421-60658259 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 47.8;salivary gland: 51.1;skeletal muscle: 119.4;tongue: 46.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 30.7;Basal respiratory cells: 30.8;Club cells: 33.9;Ionocytes: 30.5;Prostatic glandular cells: 27.4;Respiratory ciliated cells: 67.1;Skeletal myocytes: 77.3;Spermatogonia: 25.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 36.3;LHCN-M2: 142.2;RH-30: 71.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001893, CAB058690" Enhanced Supported Nucleoplasm,Nucleoli No No "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Nucleoli "CAB058690: AB_2665581, HPA001893: AB_1079991" "unprognostic (3.62e-1)" "unprognostic (5.44e-2)" "unprognostic (5.09e-2)" "prognostic unfavorable (8.92e-6)" "unprognostic (1.33e-2)" "unprognostic (1.44e-2)" "unprognostic (2.04e-3)" "prognostic favorable (3.94e-4)" "unprognostic (1.40e-1)" "unprognostic (9.15e-2)" "unprognostic (6.45e-2)" "unprognostic (1.89e-1)" "unprognostic (3.06e-8)" "unprognostic (8.61e-2)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (3.86e-1)" 5.5 0.4 0.3 0.0 0.5 0.0 1.9 0.5 1.2 15.2 1.0 0.0 0.0 0.0 0.4 1.1 0.8 0.5 0.0 0.3 0.3 0.0 0.0 1.5 0.5 0.3 0.4 0.2 0.3 47.8 19.8 0.0 0.4 13.2 0.0 0.0 51.1 0.2 119.4 0.3 0.0 0.0 0.3 0.0 0.4 1.7 0.5 9.7 1.9 46.3 0.2 1.6 0.8 0.4 15.2 3.5 0.6 28.1 17.0 20.6 0.4 4.1 10.6 4.9 4.0 0.0 8.2 0.0 2.2 0.6 2.1 4.4 10.3 6.4 2.1 0.0 17.1 2.0 1.9 6.8 0.0 0.0 0.2 15.6 4.9 2.3 0.7 36.3 0.3 1.6 5.8 0.0 142.2 2.8 0.0 0.5 0.0 0.0 8.9 0.0 71.9 0.0 5.9 16.3 2.5 0.3 5.0 0.3 6.1 0.5 3.3 0.4 13.9 6.7 5.4 7.9 6.5 0.5 0.1 0.0 1.5 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.5 1.2 0.3 0.3 0.3 0.4 0.4 0.3 0.5 0.4 0.8 3.2 1.5 0.0 0.0 0.1 30.7 30.8 0.6 0.0 1.0 0.8 0.9 0.0 33.9 1.8 0.0 0.2 0.0 0.1 1.9 0.0 0.2 1.1 0.1 1.6 0.0 0.0 0.0 0.8 0.4 5.7 0.5 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 30.5 0.0 0.0 0.6 0.0 0.3 0.0 1.9 0.0 0.8 0.0 1.0 0.1 0.2 0.0 1.2 0.0 27.4 0.0 0.1 67.1 0.2 0.0 77.3 5.1 0.0 25.0 0.1 0.1 0.3 0.1 0.1 0.0 18.3 SIX3 HPE2 ENSG00000138083 "SIX homeobox 3" O95343 2 44941702-44946071 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 22.7;choroid plexus: 12.2;parathyroid gland: 9.1;pituitary gland: 27.8;retina: 25.3" "Group enriched" "Detected in some" 14 "Bipolar cells: 203.9;Horizontal cells: 185.1;Muller glia cells: 392.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 68.7;SCLC-21H: 63.1;SH-SY5Y: 25.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 38.7;hypothalamus: 19.5" HPA067988 Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA067988: AB_2685939" "unprognostic (1.19e-3)" "unprognostic (1.05e-2)" "unprognostic (4.76e-1)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (1.76e-2)" "unprognostic (1.31e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (6.82e-2)" "unprognostic (1.22e-1)" "unprognostic (2.49e-3)" "unprognostic (3.91e-2)" "unprognostic (1.76e-1)" "unprognostic (2.73e-2)" 0.0 0.0 8.3 0.0 22.7 0.0 0.1 0.8 16.4 0.7 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 18.2 0.1 0.0 0.0 0.1 0.5 4.5 0.0 0.6 9.1 27.8 0.0 0.5 0.0 0.0 25.3 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 1.8 10.9 0.0 0.0 0.1 0.0 0.0 0.2 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 0.0 0.6 0.0 11.7 0.0 0.0 0.6 5.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 68.7 0.0 1.4 0.0 0.0 0.0 0.0 0.4 2.7 0.4 0.0 0.3 0.0 0.4 0.0 0.0 0.0 63.1 25.2 0.1 0.0 0.0 0.0 2.1 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.3 0.2 0.2 0.3 0.2 0.2 0.1 0.2 0.2 0.2 0.3 0.4 0.4 0.5 0.2 0.3 0.1 8.3 22.7 0.8 16.4 1.8 18.2 0.5 4.5 0.5 0.2 10.9 1.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 203.9 1.1 1.3 0.7 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 11.2 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 185.1 0.1 0.2 0.0 0.0 0.3 2.7 0.0 0.1 0.0 0.0 0.0 392.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.2 18.3 0.0 0.5 0.4 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SIX5 DMAHP ENSG00000177045 "SIX homeobox 5" Q8N196 19 45764785-45769252 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA042068 Approved NA NA "Cluster 72: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "HPA042068: AB_10795390" "unprognostic (3.09e-1)" "unprognostic (1.16e-2)" "unprognostic (1.39e-3)" "unprognostic (9.60e-3)" "unprognostic (2.11e-1)" "unprognostic (2.96e-3)" "unprognostic (1.00e-3)" "unprognostic (1.02e-3)" "unprognostic (3.90e-2)" "unprognostic (8.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.30e-1)" "unprognostic (1.69e-3)" "unprognostic (5.59e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-2)" "unprognostic (8.99e-2)" 19.1 23.5 8.8 5.8 8.4 0.6 20.5 8.5 10.0 37.5 13.5 35.8 6.7 34.6 8.7 14.7 37.8 8.1 25.2 7.6 8.5 20.9 24.6 12.6 4.2 11.2 10.5 45.8 41.0 9.3 15.9 8.4 8.5 34.0 4.3 0.6 28.0 15.9 16.0 12.7 14.2 12.6 9.9 12.1 25.4 8.0 9.1 2.3 29.4 5.7 2.9 30.8 22.5 7.9 3.3 19.3 25.6 39.2 16.0 15.9 13.2 7.3 15.5 11.1 9.7 4.8 12.4 1.8 7.0 11.9 13.6 7.5 7.7 8.4 3.7 9.3 11.6 2.1 18.7 13.8 14.1 0.5 11.9 15.6 13.1 7.2 9.2 16.8 9.4 7.6 9.0 3.9 3.2 10.6 2.6 18.2 17.4 10.4 10.9 9.7 2.3 7.9 12.1 4.1 1.6 10.5 21.7 10.7 16.8 10.1 10.0 18.8 5.7 11.0 10.3 10.0 8.1 4.7 5.1 1.9 15.9 0.9 12.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 8.4 8.5 10.0 7.6 8.5 11.2 10.5 8.5 9.9 9.1 7.9 5.2 0.0 7.2 7.5 1.0 3.2 5.4 7.9 4.6 0.1 11.6 14.7 0.3 11.5 3.4 5.5 0.0 6.1 0.3 2.1 3.9 6.2 0.4 7.3 14.9 5.2 3.0 0.0 0.0 6.0 13.1 9.1 4.1 8.3 0.0 11.0 6.8 7.0 1.1 5.0 0.0 8.6 2.0 0.8 1.4 1.2 15.8 0.9 0.0 3.7 0.0 3.1 0.0 0.0 0.1 5.0 2.1 12.8 5.5 6.1 0.7 1.9 4.0 0.5 0.0 8.2 8.8 0.5 3.5 4.2 2.6 4.0 0.8 4.5 5.0 1.4 SIX6 "OPTX2, Six9" ENSG00000184302 "SIX homeobox 6" O95475 14 60509146-60512850 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cataract, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pituitary gland: 28.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 29.2;Horizontal cells: 48.8;Muller glia cells: 160.9" "Cancer enriched" "Detected in single" 8 "glioma: 1.0" "Group enriched" "Detected in some" 18 "hypothalamus: 3.9;thalamus: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "JURKAT: 13.4;MOLT-4: 44.0" "Region enriched" "Detected in single" 14 "hypothalamus: 3.6" "Region enriched" "Detected in single" 12 "hypothalamus: 1.6" HPA001403 Approved Approved Nucleoplasm NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA001403: AB_1079993" "unprognostic (2.76e-1)" "unprognostic (6.14e-2)" "unprognostic (8.18e-2)" "unprognostic (5.75e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 0.1 0.0 6.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 44.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.3 0.0 0.0 1.3 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 160.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 1.7 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 SKI ENSG00000157933 "SKI proto-oncogene" P12755 1 2228319-2310213 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Craniosynostosis, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010449, HPA066567" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "CAB010449: AB_2187342, HPA066567: AB_2685692" "unprognostic (3.99e-2)" "unprognostic (3.81e-2)" "unprognostic (1.44e-1)" "unprognostic (5.42e-2)" "unprognostic (4.66e-2)" "unprognostic (7.32e-2)" "unprognostic (1.88e-1)" "unprognostic (9.14e-2)" "unprognostic (1.08e-1)" "unprognostic (4.76e-2)" "unprognostic (4.94e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-3)" "unprognostic (1.88e-1)" "unprognostic (7.82e-2)" "unprognostic (9.69e-2)" "unprognostic (5.24e-3)" 38.3 14.3 22.0 14.1 20.9 11.5 31.5 59.5 24.2 37.5 3.4 34.6 9.3 42.0 8.3 23.5 34.1 14.6 34.4 24.1 11.0 23.6 24.3 33.9 11.6 20.1 16.9 36.4 13.1 7.3 23.0 13.9 17.2 26.8 7.0 5.1 25.2 19.8 22.1 38.6 24.1 16.8 17.1 22.9 22.6 13.2 19.4 8.7 25.4 11.7 10.2 30.8 29.2 15.7 18.3 10.4 24.5 23.9 40.0 23.8 16.1 26.7 14.8 16.3 11.9 15.8 13.7 11.5 19.5 34.4 6.8 21.0 13.8 21.6 15.0 12.7 30.0 29.0 16.4 22.5 26.7 16.5 29.8 25.8 11.8 24.5 18.2 30.0 20.2 4.8 16.6 8.6 20.2 11.6 2.0 18.1 24.8 12.0 19.8 9.1 15.5 9.6 13.9 7.0 35.0 22.9 26.0 22.9 26.7 15.6 7.7 20.9 36.9 27.7 17.5 39.6 21.1 6.7 5.2 10.5 14.8 28.2 11.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 22.0 20.9 59.5 24.2 24.1 11.0 20.1 16.9 17.2 17.1 19.4 15.7 44.2 9.6 12.6 18.9 18.8 47.0 13.1 7.0 32.5 8.9 20.3 25.8 12.7 11.5 6.7 7.3 0.0 7.3 32.2 7.3 1.9 8.2 0.8 10.1 28.9 34.3 6.0 14.7 22.6 6.9 15.5 35.5 9.7 18.5 13.3 6.4 33.9 23.0 13.7 11.8 24.1 14.3 0.0 16.4 29.5 5.0 49.7 28.9 16.0 48.7 9.4 11.1 12.3 11.6 11.4 13.0 9.4 55.3 16.9 14.9 8.1 6.0 4.0 4.4 46.0 36.2 37.3 4.7 12.8 32.2 45.0 16.3 33.4 6.7 10.7 11.4 SKIV2L "170A, DDX13, HLP, SKI2W, SKIV2, SKIV2L1" ENSG00000204351 "Ski2 like RNA helicase" Q15477 6 31959117-31969751 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 42.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047122, HPA051959, HPA054419" Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitotic spindle,Cytosol" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies" "Mitotic spindle, Cytosol" "HPA047122: , HPA051959: AB_2681672, HPA054419: AB_2682482" "unprognostic (1.43e-1)" "unprognostic (5.75e-2)" "unprognostic (3.41e-2)" "unprognostic (1.66e-2)" "unprognostic (6.43e-2)" "unprognostic (7.03e-2)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.36e-2)" "unprognostic (2.14e-2)" "unprognostic (7.75e-2)" "unprognostic (7.99e-3)" "unprognostic (1.53e-3)" "prognostic unfavorable (3.02e-7)" "unprognostic (6.77e-2)" "unprognostic (2.23e-1)" "unprognostic (1.20e-1)" "unprognostic (9.06e-2)" 21.9 33.1 0.0 5.2 0.3 4.1 21.6 0.0 0.4 26.5 0.0 25.1 10.5 22.6 9.4 23.0 25.0 0.0 22.0 0.0 0.1 24.0 54.7 22.2 3.4 0.0 0.5 24.6 25.7 2.4 39.7 2.6 0.0 31.9 2.4 2.1 22.4 3.2 20.4 20.2 31.2 5.7 0.0 40.6 27.6 16.6 0.1 4.3 27.7 5.3 2.7 23.6 20.9 0.0 0.2 12.7 13.3 0.0 16.5 11.8 27.1 10.9 11.7 13.6 13.2 0.4 0.0 0.0 26.0 25.5 13.2 11.9 0.0 30.8 9.9 14.8 15.7 0.0 0.0 0.2 0.0 0.1 0.2 28.3 17.9 0.1 0.0 12.7 0.0 19.3 0.0 13.6 0.0 0.0 0.0 0.3 20.6 0.0 0.0 0.3 0.0 0.0 11.2 0.0 0.0 0.0 23.6 0.0 17.6 11.5 0.0 15.7 12.8 16.0 7.2 18.7 0.2 42.2 35.7 12.0 20.4 0.1 0.0 0.3 0.5 0.2 1.5 1.4 1.1 0.2 0.7 0.3 1.1 0.9 0.8 0.8 0.1 0.0 2.2 0.5 0.2 0.4 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 6.4 16.0 11.3 10.1 13.3 2.8 5.0 7.9 11.4 5.0 9.3 5.1 8.5 10.0 8.8 7.3 8.4 12.6 12.7 19.7 1.9 9.5 3.1 7.7 7.9 7.9 12.6 6.5 7.2 8.6 7.9 7.4 28.1 6.3 8.2 10.8 8.6 19.4 9.2 0.0 5.0 13.2 8.2 6.3 4.1 1.5 9.3 7.8 7.2 2.8 10.2 4.9 18.6 3.0 4.8 9.4 16.0 6.0 20.2 5.9 25.5 6.9 16.5 8.3 0.0 4.1 10.2 4.7 7.5 6.6 3.7 12.4 14.4 12.3 11.0 5.2 SLC10A7 "C4orf13, DKFZp313H0531, DKFZp566M114, DKFZp779O2438, MGC25043" ENSG00000120519 "Solute carrier family 10 member 7" Q0GE19 4 146253975-146521964 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 44.4;Microglial cells: 50.6;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039996 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA039996: AB_10673266" "unprognostic (9.44e-2)" "unprognostic (4.03e-1)" "unprognostic (3.39e-3)" "unprognostic (5.07e-2)" "unprognostic (1.01e-1)" "unprognostic (9.02e-2)" "unprognostic (7.96e-2)" "unprognostic (2.54e-1)" "unprognostic (3.55e-1)" "unprognostic (8.53e-2)" "unprognostic (2.68e-3)" "unprognostic (1.24e-1)" "unprognostic (1.43e-2)" "unprognostic (8.99e-2)" "unprognostic (2.79e-1)" "unprognostic (6.69e-2)" "unprognostic (9.57e-2)" 5.4 4.6 2.6 4.9 4.0 6.0 6.0 3.2 2.6 7.2 1.7 7.0 4.6 4.9 12.0 5.8 4.4 5.6 2.9 2.9 3.6 3.8 7.2 5.9 5.6 4.6 3.8 5.6 6.5 3.7 3.6 8.9 4.9 6.3 9.2 3.9 6.9 3.3 2.2 3.7 5.4 5.9 3.8 5.3 9.7 3.4 3.5 6.5 7.0 3.2 5.9 4.7 4.8 5.1 5.2 1.7 12.2 5.0 8.6 10.3 5.8 6.3 8.2 5.7 5.8 4.7 21.6 9.6 4.4 6.9 3.6 5.2 7.2 8.6 6.8 11.1 3.5 11.8 4.2 8.5 5.5 20.5 18.3 4.9 6.8 6.9 8.7 3.1 10.2 10.2 13.2 25.6 4.3 3.6 15.6 5.2 2.2 11.4 8.6 8.6 8.9 13.7 4.0 3.8 3.7 3.1 4.3 12.8 5.3 6.4 7.5 8.1 5.8 5.1 5.4 7.8 4.4 20.7 24.9 13.4 7.0 8.2 7.4 10.9 3.0 4.5 3.7 4.8 3.8 3.9 3.7 3.3 4.0 2.8 3.5 3.4 0.3 5.1 3.9 2.7 4.9 2.2 2.6 4.0 3.2 2.6 2.9 3.6 4.6 3.8 4.9 3.8 3.5 5.1 10.8 3.2 3.9 44.4 7.9 3.3 4.2 2.0 2.8 6.8 5.2 3.7 2.1 8.6 3.2 1.8 4.2 6.4 8.2 6.2 1.9 4.0 2.3 4.8 6.2 5.4 4.8 9.9 34.3 5.1 13.2 6.1 11.2 6.0 22.9 5.8 8.9 10.3 5.8 8.4 37.1 14.7 2.0 7.3 3.1 1.2 7.5 6.1 0.0 50.6 4.9 3.4 6.2 62.4 82.0 3.6 3.4 4.9 15.8 3.3 4.2 1.9 7.3 11.8 0.0 4.0 5.5 7.0 4.5 5.2 4.8 6.2 8.6 2.3 7.6 4.1 SLC17A9 "C20orf59, FLJ23412, VNUT" ENSG00000101194 "Solute carrier family 17 member 9" Q9BYT1 20 62952707-62969585 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Exocytosis, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 43.0" "Cell type enhanced" "Detected in many" "B-cells: 18.2;Gastric mucus-secreting cells: 29.0;Hepatocytes: 48.8;Hofbauer cells: 18.0;Intestinal goblet cells: 19.7;Plasma cells: 38.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 4.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 35.7;CACO-2: 32.9;Hep G2: 69.5;NB-4: 39.0;RPMI-8226: 36.1;U-937: 43.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA047470 Approved Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA047470: AB_2680060" "unprognostic (2.65e-3)" "unprognostic (2.13e-1)" "unprognostic (7.08e-2)" "unprognostic (1.97e-1)" "unprognostic (4.33e-3)" "unprognostic (5.33e-2)" "unprognostic (6.03e-2)" "unprognostic (6.84e-3)" "unprognostic (1.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (2.78e-15)" "unprognostic (6.06e-3)" "unprognostic (5.51e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" 1.3 1.0 0.3 5.8 0.5 11.4 1.3 0.7 0.7 1.9 0.7 3.7 5.5 1.5 0.2 0.8 1.9 1.3 1.3 0.6 0.8 0.9 43.0 3.5 5.2 1.2 0.9 1.7 1.4 0.0 2.2 1.7 1.3 1.3 3.1 0.0 4.0 0.6 1.0 0.7 4.2 1.4 0.9 11.1 9.5 0.4 1.2 0.7 1.2 0.1 4.2 2.7 1.7 2.0 0.0 0.0 0.0 0.2 0.3 3.1 0.1 35.7 10.0 11.4 18.0 32.9 0.0 25.9 0.0 28.3 0.0 0.0 5.0 0.0 2.8 0.0 0.0 11.5 0.9 69.5 7.7 20.9 0.0 2.5 0.0 13.6 0.0 0.0 7.6 0.1 0.1 14.6 0.0 0.0 0.9 39.0 0.0 12.9 0.2 26.9 0.0 36.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 19.4 2.6 0.0 0.0 1.2 0.0 5.0 0.3 14.2 0.0 43.8 0.0 0.0 0.9 0.0 0.7 1.7 0.5 2.2 0.0 0.4 2.6 1.7 0.0 0.3 0.0 4.9 0.3 0.0 0.1 0.7 0.3 0.5 0.7 0.7 0.6 0.8 1.2 0.9 1.3 0.9 1.2 2.0 1.1 0.0 1.1 0.0 18.2 0.9 0.2 0.3 0.0 0.4 1.0 1.0 1.3 12.8 1.0 0.0 0.0 0.3 5.5 6.4 0.0 0.3 0.7 2.6 7.3 1.4 3.0 1.7 0.7 0.4 0.9 4.0 29.0 2.5 5.1 2.4 1.4 48.8 18.0 0.0 0.4 19.7 0.0 5.1 12.4 0.6 1.2 7.2 5.4 2.8 1.3 0.1 4.1 1.0 0.1 1.7 3.1 0.7 38.6 0.6 0.2 0.4 0.8 0.1 0.0 1.6 4.2 0.4 1.0 0.0 1.1 0.8 3.6 3.8 9.3 0.6 SLC1A4 "ASCT1, SATT" ENSG00000115902 "Solute carrier family 1 member 4" P43007 2 64988477-65023865 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 59.9" "Cell type enhanced" "Detected in many" "Astrocytes: 69.9;Granulosa cells: 49.2;Melanocytes: 85.4;Plasma cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 294.5;U-266/70: 132.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034963, HPA034964" Approved Enhanced Centrosome NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Centrosome "HPA034963: AB_2797223, HPA034964: AB_2674386" "unprognostic (7.61e-2)" "prognostic favorable (3.59e-4)" "unprognostic (2.49e-1)" "unprognostic (3.19e-3)" "unprognostic (1.26e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.23e-5)" "unprognostic (1.26e-2)" "unprognostic (2.10e-1)" "unprognostic (3.16e-2)" "unprognostic (2.28e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (4.87e-4)" "unprognostic (6.37e-3)" "unprognostic (4.14e-2)" "unprognostic (3.53e-2)" "unprognostic (1.98e-2)" 4.3 26.4 49.1 9.1 46.8 13.4 13.6 32.1 48.6 14.0 18.0 9.4 6.1 12.8 8.2 7.5 4.8 3.9 6.2 43.4 56.6 1.9 9.0 4.9 10.7 37.2 43.1 13.2 29.6 5.5 13.7 6.6 52.1 9.6 8.4 19.3 7.5 7.1 40.1 18.6 5.6 12.3 29.5 7.5 8.1 11.7 59.9 20.5 5.7 17.0 19.0 4.8 6.2 30.3 15.3 11.6 6.6 34.9 14.7 9.5 9.4 28.5 14.0 11.7 19.8 3.2 2.2 49.7 6.5 44.8 14.7 43.2 13.7 3.6 12.0 20.1 5.4 26.0 13.1 30.9 31.0 43.8 23.1 4.4 73.8 15.8 24.2 3.9 7.3 49.1 20.7 122.0 8.4 13.5 37.7 29.1 4.7 20.1 13.9 13.5 1.9 125.5 4.9 7.7 29.3 14.1 17.9 16.1 294.5 3.0 19.3 47.8 1.6 16.0 19.0 31.2 17.5 132.8 71.2 118.8 23.6 86.5 86.2 0.0 2.1 1.8 0.9 4.8 1.2 0.9 0.9 1.5 3.9 0.3 0.0 0.8 0.0 5.1 9.4 7.2 3.5 1.4 49.1 46.8 32.1 48.6 43.4 56.6 37.2 43.1 52.1 29.5 59.9 30.3 3.6 0.0 2.7 69.9 13.6 20.0 2.1 6.7 46.1 6.3 21.0 7.1 5.5 1.5 1.7 1.8 33.3 2.4 20.2 2.9 0.0 2.0 32.4 5.4 8.2 5.3 8.4 6.1 20.6 9.3 1.3 4.0 5.1 5.6 7.0 49.2 7.5 13.1 17.7 6.7 25.5 9.0 6.1 6.8 11.8 47.5 11.1 11.1 85.4 8.4 5.1 14.6 2.1 5.0 3.9 7.1 0.8 29.7 65.7 2.6 0.4 1.5 5.4 17.7 0.0 5.1 7.3 2.0 0.9 5.9 6.1 2.5 10.9 0.4 5.8 1.0 SLC25A19 "DNC, MCPHA, MUP1, TPC" ENSG00000125454 "Solute carrier family 25 member 19" Q9HC21 17 75272981-75289510 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 82.2;Langerhans cells: 160.3;Spermatocytes: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021936 Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA021936: " "unprognostic (2.28e-1)" "unprognostic (7.05e-3)" "unprognostic (8.21e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (2.31e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.21e-7)" "unprognostic (6.71e-2)" "unprognostic (2.73e-1)" "unprognostic (2.85e-1)" "unprognostic (7.72e-2)" "unprognostic (1.77e-3)" "unprognostic (2.71e-3)" "unprognostic (3.58e-2)" "unprognostic (4.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.13e-1)" 10.9 31.2 11.6 16.0 12.4 8.0 6.4 13.1 13.3 7.3 12.4 9.8 9.4 6.7 2.4 8.6 6.3 6.2 10.6 11.7 12.6 10.9 8.8 11.7 22.9 14.9 12.6 6.2 8.8 8.1 4.8 12.1 13.2 6.1 8.8 3.1 6.2 3.7 14.5 4.9 8.5 7.1 13.0 14.6 10.9 33.0 14.7 8.6 6.0 16.7 18.8 11.5 5.7 14.7 28.3 34.8 6.2 18.4 13.6 7.0 20.0 18.1 7.0 20.3 20.5 59.8 17.4 89.8 12.8 6.4 17.7 24.7 43.5 20.9 25.3 26.5 70.5 41.1 40.4 58.4 11.5 58.7 44.9 6.1 11.6 31.5 25.2 4.7 33.9 44.9 51.0 41.9 6.5 59.3 61.8 59.3 13.5 55.3 67.8 47.4 19.8 85.1 14.1 19.7 60.7 15.3 19.3 51.4 22.2 10.2 32.1 47.3 12.0 12.1 24.1 23.5 49.0 102.7 53.4 95.8 9.5 66.9 15.5 0.3 21.0 2.3 16.2 25.2 16.6 36.3 12.7 15.4 24.9 29.7 14.2 14.7 1.7 10.0 14.8 31.0 17.7 14.5 11.6 12.4 13.1 13.3 11.7 12.6 14.9 12.6 13.2 13.0 14.7 14.7 5.1 6.4 6.7 3.3 27.6 15.2 10.8 6.0 2.8 1.2 5.4 7.5 0.6 2.8 6.1 7.3 2.1 7.5 13.3 8.6 23.5 6.5 18.0 5.6 8.7 6.7 3.0 11.1 3.1 5.3 82.2 8.6 9.7 3.5 11.4 2.7 2.5 2.9 44.1 3.3 3.5 6.2 4.1 9.5 160.3 24.1 3.1 31.5 24.9 4.7 38.8 1.6 11.3 2.0 2.4 5.1 8.6 3.4 26.5 14.1 6.5 6.4 3.9 6.0 6.6 5.9 10.0 79.6 11.9 7.9 12.9 8.9 12.5 11.4 11.0 9.7 SLC25A24 "APC1, DKFZp586G0123" ENSG00000085491 "Solute carrier family 25 member 24" Q6NUK1 1 108134043-108200849 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Distal enterocytes: 126.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028519, HPA063636" Enhanced Enhanced Mitochondria NA NA 19000 "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA028519: AB_10603890, HPA063636: AB_2685068" "unprognostic (1.94e-2)" "unprognostic (7.30e-3)" "prognostic favorable (1.01e-4)" "unprognostic (7.11e-2)" "unprognostic (1.64e-2)" "unprognostic (2.91e-1)" "unprognostic (8.54e-4)" "unprognostic (1.51e-2)" "unprognostic (7.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-3)" "unprognostic (6.18e-2)" "unprognostic (6.76e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 10.0 6.2 0.8 5.3 0.7 3.8 8.2 0.6 1.3 12.5 0.8 13.5 11.4 6.6 3.2 6.0 6.7 6.8 4.9 0.7 0.8 6.3 1.6 9.1 5.1 0.8 0.7 5.9 4.2 8.2 2.8 9.4 0.9 4.0 16.0 6.7 6.7 4.6 3.7 4.3 12.3 8.7 0.6 5.7 6.9 3.2 1.0 5.0 7.1 4.5 4.9 10.1 7.0 0.7 38.2 8.9 28.8 8.6 17.9 23.4 11.4 13.0 17.0 25.1 27.4 11.3 12.9 0.0 10.3 28.7 10.9 14.1 7.9 24.0 35.1 7.9 4.4 2.4 13.4 5.2 14.9 6.1 4.9 17.6 17.0 15.0 18.5 16.8 19.6 5.7 6.2 13.0 32.2 28.7 3.7 1.4 14.3 17.3 8.1 5.7 33.9 12.6 16.9 22.8 5.0 8.7 17.4 14.9 17.5 27.5 13.3 10.7 10.5 13.8 6.2 23.2 15.0 3.0 2.3 0.0 5.0 11.8 8.2 0.4 0.5 0.4 0.3 0.5 0.3 0.1 0.2 0.2 0.4 0.4 0.1 0.3 0.1 0.2 0.7 0.3 0.4 0.1 0.8 0.7 0.6 1.3 0.7 0.8 0.8 0.7 0.9 0.6 1.0 0.7 33.9 54.5 27.8 5.5 24.2 15.6 20.4 20.6 17.1 14.7 25.5 16.8 15.5 17.2 33.5 18.4 8.4 7.1 16.3 126.7 21.5 31.2 3.2 62.0 46.7 28.6 18.1 6.7 18.0 36.9 60.2 23.2 40.2 61.7 22.2 20.9 29.6 1.2 54.1 10.1 14.9 43.2 18.3 51.8 32.8 2.9 19.6 50.0 23.2 16.9 44.7 12.7 11.3 14.6 20.8 67.6 51.2 18.0 9.7 14.3 54.4 24.9 55.2 33.9 52.6 27.2 26.5 6.2 2.4 24.8 14.9 6.2 23.9 41.8 59.1 33.8 SLC26A2 "DTD, DTDST" ENSG00000155850 "Solute carrier family 26 member 2" P50443 5 149960758-149993455 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "intestine: 212.0" "Group enriched" "Detected in many" 4 "Distal enterocytes: 2026.2;Glandular and luminal cells: 684.5;Syncytiotrophoblasts: 808.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "EFO-21: 66.1;RPTEC TERT1: 151.7;TIME: 80.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041957, HPA058090" Enhanced Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041957: AB_10795646, HPA058090: AB_2683602" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "unprognostic (3.03e-2)" "prognostic favorable (7.29e-4)" "unprognostic (2.59e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.59e-1)" "unprognostic (5.64e-2)" "unprognostic (1.19e-1)" "unprognostic (7.43e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.70e-1)" "unprognostic (1.77e-1)" "unprognostic (8.12e-2)" "unprognostic (1.06e-1)" 5.2 30.7 2.2 7.8 2.3 2.5 9.2 9.5 3.8 6.3 4.0 212.0 12.9 9.3 22.8 10.7 5.0 5.5 2.8 2.2 3.5 4.9 1.7 7.3 4.0 3.8 3.4 4.8 3.4 37.7 7.1 34.0 3.5 12.2 189.6 20.8 35.8 18.4 3.9 7.8 16.1 9.3 3.8 3.7 3.3 4.2 3.9 4.2 4.5 3.7 5.9 4.7 3.0 3.4 9.5 8.6 10.5 17.3 12.6 8.8 2.5 8.9 8.0 7.0 8.5 44.7 5.1 7.4 66.1 9.5 16.8 6.8 10.0 20.5 12.4 6.0 6.4 9.3 6.7 5.2 9.4 17.3 15.2 9.8 11.8 11.7 15.2 17.3 16.8 9.0 2.4 7.1 29.6 3.0 6.6 9.1 3.2 3.2 13.5 9.5 16.3 3.9 151.7 41.6 3.2 8.1 15.6 3.6 27.2 8.1 7.3 10.0 80.4 16.0 11.8 14.2 10.7 5.2 7.3 4.3 14.7 20.6 23.5 4.9 0.5 0.3 0.9 0.3 1.1 0.5 0.5 0.8 0.7 0.5 0.8 0.9 0.3 1.1 1.6 0.7 1.1 0.5 2.2 2.3 9.5 3.8 2.2 3.5 3.8 3.4 3.5 3.8 3.9 3.4 47.4 44.8 11.3 3.3 8.5 4.6 13.2 22.9 7.4 17.1 23.8 14.6 7.8 7.2 24.2 33.1 16.7 219.2 11.5 2026.2 1.9 6.1 32.7 237.0 92.3 29.8 21.1 16.6 5.4 9.9 7.7 21.5 5.1 684.5 90.0 29.6 17.2 2.0 30.4 6.7 7.9 52.5 20.3 15.3 11.8 15.7 17.4 17.4 90.7 17.8 19.6 15.2 15.5 16.6 6.0 12.1 177.4 12.4 15.2 15.1 91.7 5.1 26.6 84.5 0.0 18.7 13.9 8.7 11.4 73.9 5.1 808.9 14.0 26.3 208.9 5.5 SLC27A4 "ACSVL4, FATP4" ENSG00000167114 "Solute carrier family 27 member 4" Q6P1M0 9 128340527-128361470 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.7;Proximal enterocytes: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007293, CAB009771" Approved Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB009771: AB_2270540, HPA007293: AB_1857062" "unprognostic (7.25e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-3)" "unprognostic (3.74e-2)" "unprognostic (2.03e-1)" "unprognostic (1.85e-3)" "unprognostic (1.31e-3)" "unprognostic (4.51e-1)" "unprognostic (4.69e-2)" "unprognostic (7.72e-2)" "unprognostic (5.07e-2)" "prognostic favorable (2.61e-5)" "unprognostic (7.29e-3)" "unprognostic (2.11e-1)" "unprognostic (3.45e-2)" "unprognostic (8.01e-3)" 11.4 14.7 22.5 8.5 23.7 2.7 11.6 25.4 30.3 17.2 12.4 22.8 66.9 14.4 6.3 61.8 10.4 7.3 20.4 22.7 25.9 28.8 40.0 11.8 6.4 29.4 23.9 8.3 21.6 15.5 12.1 5.6 28.8 13.1 9.4 6.8 16.4 7.5 16.1 41.8 41.1 9.3 19.7 11.6 16.4 25.8 27.1 5.8 15.5 6.2 9.6 15.5 23.5 24.1 20.8 41.8 21.1 28.1 31.5 9.8 23.3 16.7 11.7 20.3 14.5 30.1 20.7 19.1 13.5 19.8 24.8 70.6 25.5 20.7 6.7 19.5 37.2 11.4 35.6 28.5 17.1 21.0 17.8 12.7 29.6 21.2 17.0 9.4 23.1 26.3 27.5 13.7 20.2 56.2 26.0 22.7 9.2 51.6 63.0 30.4 19.6 36.4 38.1 32.0 34.8 19.2 27.6 57.0 20.3 11.3 26.7 8.8 32.4 23.7 22.9 26.6 22.0 11.4 17.4 6.5 24.3 13.0 27.7 0.0 2.5 1.7 4.7 3.3 3.4 2.1 2.9 3.6 4.4 0.9 2.3 2.4 1.0 1.4 4.3 3.9 2.2 2.4 22.5 23.7 25.4 30.3 22.7 25.9 29.4 23.9 28.8 19.7 27.1 24.1 4.7 0.0 1.1 12.7 2.0 2.8 1.4 4.0 1.2 9.6 5.8 3.0 5.2 7.2 2.8 9.2 12.5 6.1 2.1 53.7 1.9 13.1 4.8 3.6 5.2 5.3 13.1 4.0 27.7 16.0 6.8 3.5 14.3 9.3 8.9 5.9 3.6 20.1 11.3 8.4 29.2 18.6 8.2 6.1 1.9 5.4 1.2 5.4 1.8 15.9 10.0 5.0 6.2 8.5 26.4 26.4 30.0 4.1 3.2 3.2 100.6 9.7 1.8 7.8 6.6 4.4 4.4 11.8 7.9 11.9 6.1 5.2 2.4 7.9 25.7 2.8 SLC35A3 ENSG00000117620 "Solute carrier family 35 member A3" Q9Y2D2 1 99969351-100035634 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 211.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015253 Uncertain NA NA "Cluster 6: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA015253: AB_1857106" "unprognostic (1.05e-1)" "unprognostic (2.69e-1)" "unprognostic (1.57e-3)" "unprognostic (5.89e-2)" "unprognostic (9.64e-2)" "unprognostic (1.61e-1)" "unprognostic (1.72e-1)" "unprognostic (4.02e-2)" "unprognostic (2.59e-2)" "unprognostic (1.47e-1)" "unprognostic (1.76e-3)" "unprognostic (1.69e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-3)" "unprognostic (2.32e-1)" "unprognostic (2.73e-2)" "unprognostic (9.34e-2)" 11.6 7.3 4.3 10.4 5.1 11.4 18.3 6.6 5.8 19.1 10.0 53.3 49.7 9.6 11.4 14.4 13.1 13.5 5.5 4.1 4.7 21.3 37.3 11.5 8.0 4.7 4.6 8.1 11.5 19.8 4.8 10.2 5.1 23.0 53.8 6.9 22.0 11.6 4.9 10.8 41.4 8.8 4.5 7.9 33.4 2.8 4.9 18.9 24.9 6.1 8.9 10.5 10.2 6.3 28.3 7.6 6.7 7.1 14.8 12.9 26.7 24.5 14.8 9.4 13.6 4.9 15.1 15.1 30.0 14.3 13.3 16.0 12.7 11.0 21.6 18.7 9.4 13.7 10.7 11.8 9.2 22.1 1.6 6.8 12.1 11.5 22.2 11.3 11.1 11.9 23.0 21.9 19.3 7.1 14.6 11.4 8.2 16.0 24.9 4.5 20.4 9.4 17.1 16.0 8.6 4.8 17.0 32.3 13.7 6.2 19.7 16.6 13.0 14.3 13.0 32.0 13.3 12.9 16.2 11.2 23.0 13.5 6.1 4.4 2.1 1.1 2.2 2.1 2.5 2.5 2.2 2.6 1.7 1.8 2.7 2.3 0.6 4.3 1.7 5.0 2.8 1.9 4.3 5.1 6.6 5.8 4.1 4.7 4.7 4.6 5.1 4.5 4.9 6.3 23.5 80.1 28.6 12.4 17.8 25.0 21.6 30.5 18.8 15.7 33.9 15.4 8.8 27.1 50.5 55.2 20.9 19.4 51.4 211.0 7.9 18.1 4.4 49.4 22.4 20.5 19.8 9.7 24.4 15.3 30.5 17.0 43.3 46.3 17.1 19.5 20.7 49.3 14.2 10.1 26.6 110.6 22.4 17.8 17.1 2.1 13.4 14.2 8.8 23.4 18.0 19.0 14.4 30.2 46.7 21.7 82.8 13.2 25.6 43.3 112.4 25.3 92.6 25.1 6.6 14.4 17.7 16.2 8.3 21.2 29.7 23.3 23.8 12.8 116.4 48.4 SLC35D1 "KIAA0260, UGTREL7" ENSG00000116704 "Solute carrier family 35 member D1" Q9NTN3 1 66999350-67054148 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 74.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.6;Early spermatids: 73.5;Hepatocytes: 114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.91e-2)" "unprognostic (3.69e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (7.47e-4)" "unprognostic (2.63e-1)" "unprognostic (6.53e-2)" "unprognostic (2.49e-2)" "prognostic unfavorable (6.55e-4)" "unprognostic (2.12e-3)" "unprognostic (6.39e-2)" "unprognostic (6.75e-2)" "unprognostic (2.07e-1)" "unprognostic (7.65e-2)" "unprognostic (1.55e-1)" "unprognostic (2.43e-1)" "unprognostic (4.08e-3)" "unprognostic (3.20e-1)" 4.9 6.6 4.0 7.8 4.6 8.9 5.2 4.1 4.2 7.6 9.9 26.0 15.9 5.7 4.9 5.3 5.0 6.4 3.7 3.8 4.2 12.5 74.7 3.7 7.5 4.7 6.1 7.8 7.5 8.1 5.6 9.5 4.8 7.2 26.8 12.3 4.4 5.7 7.5 9.8 16.3 6.9 4.0 4.2 12.9 6.2 5.8 10.1 6.4 5.0 8.6 7.3 6.8 7.0 8.3 4.7 14.2 12.0 14.4 16.6 16.8 18.4 24.1 13.1 9.1 10.2 2.0 25.7 7.9 14.6 15.4 12.5 9.9 11.6 16.4 25.8 4.6 19.2 9.8 20.2 12.1 22.0 12.2 16.3 25.4 15.4 10.9 21.0 5.1 10.6 11.8 13.3 32.0 2.8 13.6 6.8 5.9 22.5 6.4 10.4 29.3 2.9 6.0 15.6 1.7 6.3 27.8 8.5 11.9 7.9 7.0 16.2 5.6 24.2 5.7 15.0 17.9 27.6 15.4 14.1 17.2 3.3 10.4 8.5 0.9 2.6 2.0 0.7 2.4 1.3 1.5 1.6 1.1 0.9 2.1 2.0 0.2 3.5 1.7 0.6 2.8 0.9 4.0 4.6 4.1 4.2 3.8 4.2 4.7 6.1 4.8 4.0 5.8 7.0 4.9 6.4 2.2 34.6 12.8 5.5 5.9 9.4 13.1 6.9 7.5 4.8 3.1 20.0 4.6 5.5 12.5 40.5 18.3 75.6 0.0 3.1 73.5 6.3 10.9 4.3 15.0 9.1 22.8 9.6 5.7 8.3 14.8 8.7 4.5 13.2 7.5 114.3 6.9 6.7 28.2 18.9 2.0 8.8 4.6 13.7 6.2 5.5 1.8 23.4 3.1 17.8 9.2 37.7 51.2 8.3 20.8 4.5 9.3 5.8 24.9 10.6 7.5 9.4 0.0 8.6 7.5 7.7 6.4 8.2 7.7 16.3 12.8 11.3 21.7 8.8 SLC39A13 FLJ25785 ENSG00000165915 "Solute carrier family 39 member 13" Q96H72 11 47407132-47416496 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 13 "Early spermatids: 298.2;Late spermatids: 905.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043971 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA043971: AB_10959744" "unprognostic (7.84e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (1.18e-1)" "unprognostic (8.56e-3)" "unprognostic (3.81e-2)" "unprognostic (7.44e-3)" "unprognostic (1.36e-1)" "unprognostic (5.40e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (1.39e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.96e-4)" "unprognostic (3.16e-1)" "unprognostic (1.73e-1)" "unprognostic (8.61e-2)" "unprognostic (4.12e-1)" 40.9 42.4 28.3 24.2 31.4 8.3 37.5 30.6 36.3 51.1 30.4 53.4 14.0 77.9 8.8 21.8 48.1 20.2 59.5 26.0 27.3 80.4 26.7 61.4 18.2 33.0 29.7 50.9 42.3 27.2 51.3 40.6 30.4 52.7 6.8 11.0 31.3 26.2 31.4 32.4 31.8 26.6 26.8 36.5 41.2 73.4 35.0 12.3 46.8 12.6 8.7 45.6 37.4 28.5 23.3 20.4 23.5 26.7 56.3 78.2 6.8 89.7 66.2 50.4 57.0 8.1 15.7 8.8 22.9 69.6 49.6 38.3 7.1 61.7 13.9 25.7 25.9 4.7 52.7 16.7 84.3 8.1 11.0 65.4 43.4 31.9 26.1 62.9 53.4 16.9 4.5 19.6 54.8 20.7 17.4 11.5 11.0 19.8 28.2 20.6 33.6 8.9 86.1 11.1 19.9 37.0 26.9 49.1 26.2 8.7 32.8 11.7 76.0 76.6 34.6 88.1 42.7 14.9 5.2 4.1 85.2 11.2 57.3 2.1 3.6 3.2 12.4 13.3 8.5 4.1 8.2 8.9 4.6 5.1 7.5 6.4 6.6 7.4 15.3 4.9 4.5 5.9 28.3 31.4 30.6 36.3 26.0 27.3 33.0 29.7 30.4 26.8 35.0 28.5 20.0 9.6 6.4 18.6 6.7 18.2 18.3 23.0 17.1 24.0 11.5 15.6 18.3 15.7 8.0 29.5 12.5 11.1 11.6 3.4 9.8 32.9 298.2 6.5 20.3 20.9 9.6 4.4 9.6 20.7 16.4 37.8 6.6 13.1 5.7 15.4 21.8 6.2 18.9 32.0 11.7 7.9 14.2 5.3 12.2 905.5 32.9 9.3 19.6 4.7 26.6 16.7 11.3 8.0 10.1 35.5 8.3 40.3 8.1 23.5 8.2 8.8 4.5 17.0 46.0 16.1 36.2 12.7 6.4 2.4 4.1 19.6 9.6 36.7 5.7 8.3 SLC9A6 "KIAA0267, NHE6" ENSG00000198689 "Solute carrier family 9 member A6" Q92581 X 135973841-136047269 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.3;Horizontal cells: 48.8;Inhibitory neurons: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059445, HPA059590" Enhanced Supported Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 18: U-2197 - ECM organization" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA059445: AB_2684021, HPA059590: AB_2684075" "unprognostic (1.35e-1)" "unprognostic (8.28e-3)" "unprognostic (4.36e-1)" "unprognostic (4.93e-2)" "unprognostic (1.84e-1)" "unprognostic (1.19e-1)" "unprognostic (2.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.15e-1)" "unprognostic (2.72e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (7.07e-2)" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (4.49e-2)" "unprognostic (5.06e-2)" 5.1 6.3 11.6 5.6 11.9 4.6 3.3 1.2 15.7 5.6 0.0 6.0 8.5 6.4 3.3 6.3 5.7 5.5 8.6 12.7 19.0 6.9 4.5 6.7 5.7 7.8 4.4 8.0 3.8 10.4 2.2 4.7 8.9 4.0 6.1 14.4 4.1 4.9 7.5 4.7 7.8 7.4 3.4 5.7 5.8 5.8 15.3 5.6 6.7 7.1 6.6 5.6 1.6 4.2 20.0 10.5 9.1 3.8 14.8 14.2 17.3 15.9 16.9 13.3 27.9 9.2 15.5 14.8 35.2 18.4 19.8 11.6 14.3 14.0 19.1 11.7 12.9 4.0 15.3 5.3 7.9 11.6 13.3 7.7 11.6 22.0 10.8 9.4 11.2 12.5 7.5 20.5 14.9 8.7 15.5 3.4 6.0 7.1 14.0 10.4 16.0 15.2 9.4 9.8 9.5 7.2 11.4 1.2 8.9 8.8 4.5 8.7 16.4 16.5 10.9 24.5 20.7 9.6 23.8 12.7 10.0 19.4 9.4 2.0 5.0 3.0 6.4 7.0 11.1 4.1 7.1 5.9 5.8 2.6 7.6 5.7 2.0 5.1 6.0 3.5 6.9 5.4 11.6 11.9 1.2 15.7 12.7 19.0 7.8 4.4 8.9 3.4 15.3 4.2 4.3 3.2 5.4 22.9 5.9 7.5 1.4 6.2 7.4 14.2 2.7 3.4 11.2 12.8 4.0 12.9 8.4 2.5 6.1 8.9 0.0 4.3 0.8 4.2 4.1 4.9 10.7 5.0 40.3 6.0 2.4 5.1 8.6 6.8 1.3 4.6 8.2 9.6 9.9 48.8 42.0 4.0 8.2 13.0 7.0 1.4 5.6 9.8 8.8 15.9 8.2 12.9 4.1 19.6 22.7 6.1 6.0 4.5 3.8 2.0 10.3 6.0 3.1 7.8 0.0 5.1 8.4 9.0 11.9 7.0 6.8 2.9 8.9 3.1 6.0 3.1 SLITRK6 FLJ22774 ENSG00000184564 "SLIT and NTRK like family member 6" Q9H5Y7 13 85792790-85806683 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Sensory transduction, Vision" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 27.7;urinary bladder: 14.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 22.8;Bipolar cells: 41.7;Club cells: 27.4;Ionocytes: 16.2;Respiratory ciliated cells: 41.6" "Cancer enhanced" "Detected in many" "breast cancer: 21.1;urothelial cancer: 18.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 28.8;OE19: 24.2;RT4: 101.4;WM-115: 23.7" "Region enhanced" "Detected in many" "thalamus: 22.6" "Low region specificity" "Detected in many" "HPA014491, HPA014513" Uncertain Supported "Plasma membrane" NA NA 28000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA014491: AB_10601603, HPA014513: AB_2669026" "unprognostic (6.14e-2)" "unprognostic (5.21e-3)" "unprognostic (1.40e-1)" "unprognostic (2.66e-2)" "unprognostic (2.46e-2)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.69e-1)" "unprognostic (4.82e-2)" "unprognostic (7.60e-2)" "unprognostic (7.92e-2)" "unprognostic (3.31e-5)" "unprognostic (5.60e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (2.51e-2)" 0.1 0.2 1.0 0.9 4.4 0.0 3.2 2.2 1.9 1.2 0.1 5.5 3.5 1.0 2.5 1.9 0.5 1.4 1.5 0.2 2.0 0.1 0.9 3.3 0.0 0.6 2.3 0.0 0.2 0.0 0.1 0.9 0.9 7.6 6.8 4.8 27.7 2.2 0.0 5.6 5.7 0.4 0.3 0.1 1.5 0.3 5.7 0.2 0.3 0.1 0.1 14.7 1.4 0.4 0.0 2.9 0.1 0.5 0.0 0.0 0.0 2.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 4.9 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 28.8 0.0 3.3 2.7 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.0 0.0 24.2 1.9 0.2 0.0 0.0 0.0 101.4 1.0 1.2 0.5 0.1 0.1 1.7 0.5 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 23.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 4.4 2.2 1.9 0.2 2.0 0.6 2.3 0.9 0.3 5.7 0.4 0.1 0.0 1.8 0.0 0.0 3.8 5.0 22.8 0.0 41.7 5.3 1.5 0.4 0.0 27.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.2 4.3 0.3 0.0 0.0 0.1 0.0 0.0 2.0 0.0 2.7 0.0 2.2 2.2 0.0 0.2 0.0 0.4 1.7 16.2 0.0 0.6 0.0 9.6 0.1 0.0 1.0 0.0 0.6 0.0 0.0 0.0 1.8 0.0 0.4 0.0 1.5 0.0 0.1 41.6 2.0 0.0 0.0 0.8 0.0 0.1 3.8 2.4 0.0 0.2 0.1 0.5 4.5 SLURP1 "ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM" ENSG00000126233 "Secreted LY6/PLAUR domain containing 1" P55000 8 142740949-142742406 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Cytokine "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 1039.2;skin 1: 858.5" "Group enriched" "Detected in some" 16 "Squamous epithelial cells: 20.8;Suprabasal keratinocytes: 65.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 66.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.3;MCF7: 1.5;RT4: 1.1;T-47d: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050967 Approved "Secreted in other tissues" NA NA 7700000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA050967: AB_2681293" "unprognostic (1.22e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.42e-2)" "unprognostic (1.84e-1)" "unprognostic (7.32e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-4)" "unprognostic (1.58e-1)" "unprognostic (2.98e-1)" "unprognostic (1.43e-1)" 0.9 0.6 0.1 0.0 0.0 0.0 11.3 0.7 0.5 105.0 0.0 0.3 0.0 0.2 0.0 1039.2 0.2 0.2 0.4 0.1 0.0 0.2 0.5 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.5 0.0 0.0 0.3 0.0 0.0 70.1 0.0 1.4 858.5 0.3 0.0 0.0 0.2 0.8 0.3 0.1 0.9 0.2 0.0 17.4 0.3 206.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.6 0.0 0.0 1.8 1.5 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 20.8 65.8 0.0 0.0 0.0 0.0 0.8 SMAD3 "HsT17436, JV15-2, MADH3" ENSG00000166949 "SMAD family member 3" P84022 15 67063763-67195173 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 162.5;Prostatic glandular cells: 149.3;Urothelial cells: 276.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008094, HPA046386, HPA067203, CAB069409" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "CAB008094: AB_2302271, CAB069409: AB_1622941, HPA046386: AB_2679647, HPA067203: AB_2685803" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (1.06e-1)" "unprognostic (1.99e-2)" "unprognostic (1.61e-1)" "unprognostic (1.98e-2)" "unprognostic (8.40e-3)" "unprognostic (1.80e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (2.93e-1)" "unprognostic (2.14e-2)" "unprognostic (3.10e-1)" "unprognostic (1.79e-1)" "unprognostic (1.15e-1)" "unprognostic (5.97e-2)" 30.0 6.3 17.9 15.8 22.4 18.8 22.2 6.8 16.1 32.2 31.5 15.4 17.7 20.3 13.6 51.9 23.3 21.2 28.1 16.1 9.3 35.7 19.8 21.4 16.8 17.0 9.0 30.7 18.2 10.5 14.5 16.8 9.3 24.4 12.9 6.2 17.2 13.8 55.0 29.1 21.6 21.1 10.9 15.4 22.2 3.9 12.9 19.6 30.2 39.0 25.7 43.6 31.5 8.5 49.3 157.0 30.6 13.9 50.8 115.9 22.5 27.6 114.0 37.8 30.7 33.7 125.3 16.5 36.6 79.4 169.8 111.3 31.2 116.9 38.1 13.1 11.9 1.8 43.4 26.2 38.2 6.6 2.7 106.5 26.7 33.2 27.7 83.2 128.2 5.2 40.3 40.8 47.1 24.2 1.5 26.0 17.7 26.1 50.5 1.6 9.1 5.9 25.2 149.4 0.8 10.3 36.6 19.5 32.5 59.2 5.3 30.2 109.4 50.4 47.1 36.5 31.7 16.5 5.0 21.0 45.8 7.0 45.9 0.0 1.0 2.3 3.2 0.9 3.3 1.2 3.6 3.4 1.0 2.8 1.6 1.4 0.0 0.3 0.9 1.5 1.9 1.1 17.9 22.4 6.8 16.1 16.1 9.3 17.0 9.0 9.3 10.9 12.9 8.5 18.2 48.1 19.9 28.4 33.9 89.0 90.2 70.6 53.5 10.8 13.3 10.5 12.2 17.2 49.6 36.8 6.2 1.1 19.7 48.2 3.9 61.9 1.0 23.6 30.2 26.6 3.5 9.1 63.2 50.7 4.2 42.6 28.5 75.2 24.1 162.5 11.4 12.6 10.7 0.0 6.9 13.0 24.4 6.2 40.8 5.7 26.8 18.8 21.4 67.5 9.7 8.5 20.6 140.2 1.3 99.7 49.2 20.7 10.6 149.3 34.2 14.0 52.2 0.6 26.3 28.9 27.5 0.6 2.3 70.3 48.9 1.6 21.6 18.8 16.6 276.2 SMAD4 "DPC4, MADH4" ENSG00000141646 "SMAD family member 4" Q13485 18 51028394-51085045 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019154 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" Centrosome "HPA019154: AB_1853480" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (4.83e-2)" "unprognostic (1.17e-2)" "unprognostic (4.05e-1)" "unprognostic (7.29e-3)" "unprognostic (9.00e-2)" "unprognostic (4.01e-2)" "unprognostic (2.51e-2)" "unprognostic (1.03e-3)" "unprognostic (4.40e-2)" "prognostic favorable (1.92e-5)" "unprognostic (2.62e-2)" "unprognostic (4.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" 16.4 11.8 9.0 10.9 10.3 10.6 17.2 21.7 10.5 18.5 11.2 14.9 11.9 20.6 9.8 15.7 16.3 12.8 14.1 11.7 10.0 16.1 19.1 13.1 12.7 9.0 8.2 24.0 21.4 19.9 11.3 18.9 9.4 21.8 14.3 18.3 14.0 18.0 24.9 14.6 12.1 18.9 8.0 13.9 15.2 14.2 11.9 17.7 21.4 24.9 14.5 13.5 13.1 13.8 16.4 22.5 59.4 16.6 23.9 36.6 31.4 27.7 32.2 39.4 49.6 13.0 3.8 25.9 7.8 25.6 19.6 24.9 33.6 13.2 40.7 19.3 14.8 20.6 20.5 15.9 23.7 34.8 13.1 16.6 21.9 19.1 27.8 37.0 28.7 14.0 21.9 25.8 23.5 9.0 18.8 10.0 31.2 9.1 14.3 23.3 30.6 26.9 18.2 7.4 34.4 20.3 27.0 5.0 18.8 24.8 13.3 19.4 20.0 34.5 13.3 8.8 19.7 30.6 28.6 26.2 21.2 12.8 22.6 0.3 0.6 0.6 1.0 0.4 1.1 0.7 1.0 0.8 1.2 0.9 1.2 1.5 1.0 1.0 0.4 1.0 1.4 0.5 9.0 10.3 21.7 10.5 11.7 10.0 9.0 8.2 9.4 8.0 11.9 13.8 32.5 22.4 29.1 55.2 21.0 25.6 20.9 15.1 18.8 17.1 27.3 20.4 38.8 24.3 19.3 22.0 20.9 20.7 24.0 22.7 11.7 16.9 10.6 30.4 36.6 26.2 39.6 12.4 37.0 12.5 20.6 30.3 28.5 35.2 4.5 132.4 28.5 44.1 15.1 15.2 39.0 32.1 16.2 28.5 20.9 16.2 33.2 21.1 28.4 49.6 16.9 20.4 17.5 41.2 72.5 20.1 21.0 30.5 24.8 36.3 26.7 22.6 22.4 20.0 26.3 32.2 34.2 17.2 18.8 20.9 27.3 12.6 20.1 22.1 24.5 29.7 SMAD6 "HsT17432, MADH6, MADH7" ENSG00000137834 "SMAD family member 6" O43541 15 66702236-66782849 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 30.1;lung: 27.9" "Cell type enhanced" "Detected in many" "Endothelial cells: 25.1;Hepatic stellate cells: 91.4;Microglial cells: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 29.8;HaCaT: 18.2;HeLa: 28.6;U-2197: 17.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061917 Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA061917: AB_2684637" "unprognostic (1.20e-1)" "unprognostic (7.43e-3)" "unprognostic (5.62e-2)" "unprognostic (1.26e-1)" "unprognostic (3.02e-1)" "unprognostic (3.50e-3)" "unprognostic (9.59e-2)" "unprognostic (4.50e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (1.10e-3)" "unprognostic (1.68e-1)" "unprognostic (1.67e-2)" "unprognostic (1.55e-3)" "unprognostic (4.30e-2)" "unprognostic (1.33e-1)" "prognostic favorable (5.45e-5)" 9.5 2.6 5.2 1.6 4.9 0.1 7.6 4.9 4.3 6.8 8.6 3.7 1.9 6.2 0.6 2.1 5.4 1.4 30.1 3.4 4.1 8.9 6.7 27.9 0.5 7.6 5.4 5.9 2.7 1.1 3.4 7.4 5.8 7.0 1.1 0.9 2.1 3.5 1.6 2.4 3.9 0.9 4.4 2.6 5.5 1.8 6.8 0.4 15.5 1.5 0.2 8.0 5.7 4.6 1.3 10.2 1.6 3.5 6.0 1.6 9.4 7.2 0.1 1.1 0.1 2.0 4.6 0.7 29.8 6.1 0.9 18.2 2.2 0.0 0.2 2.3 8.4 16.1 28.6 1.7 0.7 0.1 1.2 2.0 0.0 0.1 0.0 3.4 1.3 5.1 1.4 1.0 0.5 2.0 0.1 4.4 3.0 10.5 3.8 0.0 1.8 2.2 3.4 8.1 3.6 1.6 3.9 4.3 0.8 5.9 1.4 2.9 6.2 4.3 5.5 17.6 1.4 0.5 1.8 0.3 3.1 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 4.9 4.9 4.3 3.4 4.1 7.6 5.4 5.8 4.4 6.8 4.6 19.8 12.8 6.0 5.2 0.9 0.8 1.2 2.1 0.6 0.6 0.9 1.1 4.9 4.3 3.0 1.8 2.1 0.8 0.1 4.3 3.9 4.7 3.4 8.3 5.5 25.1 0.0 0.0 0.3 5.8 0.9 4.9 5.1 6.5 4.5 5.9 91.4 4.0 1.7 0.0 0.3 2.1 0.0 10.0 0.3 1.4 2.8 1.2 0.0 57.1 0.7 10.2 0.0 0.5 0.4 8.4 1.5 8.2 0.0 1.3 2.1 1.9 0.1 0.6 0.0 0.9 1.5 0.2 3.2 0.4 0.1 0.8 0.4 0.1 5.5 0.4 SMARCA2 "BAF190, BRM, hBRM, hSNF2a, SNF2, SNF2L2, SNF2LA, Sth1p, SWI2" ENSG00000080503 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2" P51531 9 1980290-2193624 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase" "Disease variant, Hypotrichosis, Mental retardation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 246.5;Inhibitory neurons: 263.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "HDLM-2: 1486.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029981, CAB037276" Enhanced Approved "Nucleoplasm,Vesicles,Intermediate filaments" NA NA 19000 "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "Intermediate filaments" "CAB037276: AB_477083, HPA029981: AB_10602406" "unprognostic (5.34e-2)" "unprognostic (1.99e-2)" "unprognostic (6.27e-2)" "unprognostic (6.53e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (4.91e-2)" "unprognostic (2.80e-2)" "unprognostic (2.62e-1)" "unprognostic (3.97e-1)" "unprognostic (3.60e-3)" "unprognostic (9.64e-2)" "prognostic favorable (1.26e-6)" "unprognostic (3.09e-1)" "unprognostic (2.81e-1)" "unprognostic (8.32e-3)" "unprognostic (8.50e-2)" 51.9 55.9 68.9 36.1 73.9 95.7 62.0 87.4 81.7 42.1 40.2 31.0 20.2 53.2 57.3 41.7 57.4 46.0 43.8 60.3 53.7 45.9 58.3 40.3 50.9 43.2 54.4 166.0 36.8 170.3 32.7 48.2 50.6 42.5 31.7 63.6 50.7 53.2 97.7 48.2 27.7 44.2 40.3 52.3 32.0 56.3 55.7 42.2 55.7 60.1 47.8 31.8 28.8 52.9 45.7 32.9 23.7 33.8 47.2 56.6 71.7 59.4 44.6 24.9 19.5 0.5 17.7 76.2 22.0 50.7 13.5 18.8 12.9 46.5 17.6 1486.7 20.2 208.3 88.2 16.2 18.7 88.3 118.1 37.6 17.5 24.9 46.4 44.9 40.3 35.4 7.3 255.1 43.0 19.1 22.2 72.3 23.4 26.4 12.6 97.6 30.5 69.4 57.6 40.9 15.3 14.0 36.2 8.3 14.9 34.1 16.3 55.8 49.1 40.6 19.8 25.8 27.3 22.9 31.8 33.6 43.5 32.5 11.4 26.1 5.2 15.8 10.8 7.2 10.4 12.3 10.5 11.2 6.4 9.4 13.1 10.3 14.6 9.9 10.3 12.5 12.6 5.0 68.9 73.9 87.4 81.7 60.3 53.7 43.2 54.4 50.6 40.3 55.7 52.9 83.9 73.7 70.6 246.5 57.2 58.6 18.3 55.0 82.6 57.6 103.7 74.3 95.2 31.5 54.1 106.7 37.5 99.3 102.8 32.0 31.3 30.6 38.0 44.1 61.6 69.0 37.2 41.2 216.2 22.4 24.5 65.7 19.4 45.2 48.0 27.9 36.8 62.0 31.5 35.3 263.2 31.2 48.8 54.9 34.7 22.6 76.7 57.5 49.8 142.4 45.2 53.4 43.3 120.6 100.8 18.7 15.1 86.9 71.4 13.9 26.9 18.5 88.3 37.4 13.1 58.7 40.3 42.9 14.6 66.2 52.7 88.7 74.8 56.1 28.2 12.7 SMARCA4 "BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2" ENSG00000127616 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4" P51532 19 10960932-11079426 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase, Repressor, RNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 372.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004208, HPA048340" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Nucleoli rim" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Nucleoli fibrillar center, Nucleoli rim" "CAB004208: AB_626762, HPA048340: " "unprognostic (2.68e-1)" "unprognostic (4.85e-2)" "unprognostic (1.71e-1)" "unprognostic (3.43e-3)" "unprognostic (1.40e-1)" "unprognostic (6.33e-3)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.19e-2)" "unprognostic (7.29e-2)" "unprognostic (1.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.15e-2)" "unprognostic (6.80e-3)" "unprognostic (6.83e-3)" "unprognostic (5.44e-2)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" 13.8 16.2 14.4 22.6 14.3 31.8 13.0 15.3 23.7 16.1 13.2 18.1 19.9 14.5 9.5 32.9 20.8 13.3 16.2 15.4 9.6 15.7 8.6 17.9 27.0 10.4 10.4 14.9 18.3 22.9 11.1 20.2 11.0 17.7 12.9 19.7 25.9 15.6 23.7 28.1 17.2 14.5 3.9 19.5 20.4 30.2 11.8 43.1 20.6 13.9 23.7 17.4 14.7 19.3 92.5 5.0 157.2 149.8 30.3 25.4 68.9 62.7 37.2 74.6 54.9 126.9 4.0 215.4 94.2 54.9 3.0 65.9 123.6 77.5 40.8 89.5 93.3 171.3 76.5 149.6 45.7 125.5 82.0 43.1 36.7 63.1 64.5 33.3 67.5 92.0 156.7 78.3 59.2 188.0 210.0 107.5 159.9 45.1 134.7 220.6 99.5 111.7 47.9 114.8 177.8 161.7 66.6 84.4 73.5 50.1 71.9 93.3 90.9 110.3 57.3 102.5 104.9 160.6 192.2 209.1 62.6 118.5 96.0 5.7 5.8 6.4 9.3 6.9 8.2 5.3 6.8 7.9 6.1 6.8 7.6 7.5 3.4 8.5 10.8 7.9 6.4 4.7 14.4 14.3 15.3 23.7 15.4 9.6 10.4 10.4 11.0 3.9 11.8 19.3 25.4 67.3 72.6 27.4 28.5 37.0 43.7 43.8 24.5 91.3 42.2 28.4 372.9 40.0 62.7 44.1 70.9 65.9 21.2 60.1 41.1 79.8 53.0 58.8 49.2 58.3 63.2 41.8 32.2 61.4 57.3 43.8 50.0 63.5 30.4 75.3 28.5 21.9 42.3 101.0 39.6 47.7 57.0 23.8 21.5 37.6 26.1 30.4 16.0 14.0 43.8 36.1 23.7 32.6 28.1 76.4 41.8 13.5 37.6 66.0 29.8 27.6 62.5 69.1 13.1 45.1 66.4 99.4 86.0 52.2 51.7 61.0 30.4 68.1 60.5 50.1 SMARCAD1 "DKFZP762K2015, ETL1, KIAA1122" ENSG00000163104 "SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1" Q9H4L7 4 94207611-94291292 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 86.5;Inhibitory neurons: 82.5;Oligodendrocyte precursor cells: 86.5;Oligodendrocytes: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016737 Approved Enhanced Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA016737: AB_1857271" "unprognostic (5.01e-2)" "unprognostic (5.83e-2)" "unprognostic (2.59e-3)" "unprognostic (1.23e-1)" "unprognostic (8.41e-3)" "unprognostic (9.08e-3)" "prognostic unfavorable (3.22e-5)" "unprognostic (2.45e-1)" "unprognostic (3.49e-3)" "unprognostic (3.55e-1)" "unprognostic (2.57e-2)" "unprognostic (7.72e-2)" "unprognostic (2.99e-2)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "unprognostic (3.20e-3)" 10.0 9.5 7.1 11.2 7.8 7.5 15.2 12.0 8.5 10.6 7.5 9.4 9.7 14.5 12.6 10.5 10.7 10.3 7.6 7.3 8.6 11.7 9.8 9.7 16.0 7.2 7.4 14.2 8.7 11.7 11.0 14.1 7.7 11.1 12.3 14.6 8.9 10.0 7.3 20.8 9.5 11.8 7.7 11.9 10.8 12.2 8.2 18.6 15.0 6.8 14.2 11.2 9.7 9.9 15.0 18.6 59.1 38.1 16.5 26.6 30.1 26.8 24.3 21.8 20.3 18.2 23.7 37.8 17.7 23.1 19.8 12.9 42.3 22.4 30.7 29.8 18.7 27.5 20.5 27.2 24.4 41.2 28.9 27.8 17.8 27.3 34.9 27.0 33.7 33.3 46.7 15.5 32.4 12.3 69.1 21.3 40.1 19.1 9.4 40.1 33.6 19.6 24.6 18.4 33.8 49.9 20.1 32.8 28.6 36.7 17.1 26.9 32.3 27.6 29.9 17.1 20.3 21.8 34.8 45.1 25.7 21.2 34.8 2.7 1.3 0.2 2.3 1.7 2.5 2.9 2.6 2.6 2.4 2.4 2.8 3.3 0.0 4.5 1.7 2.1 2.3 1.3 7.1 7.8 12.0 8.5 7.3 8.6 7.2 7.4 7.7 7.7 8.2 9.9 19.0 12.8 11.3 56.2 16.7 11.7 6.5 12.8 25.6 20.9 15.5 13.2 12.7 4.3 24.7 9.2 16.7 13.5 20.1 7.1 1.9 12.4 2.1 27.6 32.3 17.8 9.0 25.5 86.5 10.0 11.8 19.9 17.9 17.9 24.0 29.5 13.2 13.5 10.8 18.5 82.5 12.9 14.2 14.6 5.4 3.1 14.3 13.7 3.6 47.8 12.6 8.1 17.5 86.5 99.5 15.0 6.3 18.4 16.4 7.7 4.4 15.5 26.8 18.8 6.6 21.1 16.2 25.9 34.8 18.7 9.7 9.6 17.3 26.2 12.6 5.8 SMARCAL1 "HARP, HHARP" ENSG00000138375 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1" Q9NZC9 2 216412414-216483053 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Helicase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020337 Uncertain Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA020337: AB_2670410" "unprognostic (4.56e-1)" "unprognostic (1.05e-1)" "unprognostic (1.65e-1)" "unprognostic (2.20e-2)" "unprognostic (3.39e-2)" "unprognostic (2.68e-2)" "prognostic unfavorable (5.22e-4)" "unprognostic (4.35e-3)" "unprognostic (3.31e-2)" "unprognostic (2.33e-1)" "unprognostic (1.36e-1)" "unprognostic (7.46e-2)" "unprognostic (2.00e-2)" "unprognostic (2.67e-1)" "unprognostic (1.41e-1)" "unprognostic (1.97e-1)" "unprognostic (3.16e-1)" 9.2 9.8 7.5 8.9 10.3 9.1 8.8 8.0 9.7 10.6 7.6 8.0 6.8 10.7 7.5 9.8 11.0 9.5 8.9 8.0 9.0 7.2 6.7 7.9 13.1 10.6 9.1 16.3 8.2 10.8 9.3 9.1 10.6 8.1 7.4 5.6 8.0 8.9 10.5 10.6 7.9 10.1 8.4 9.7 8.0 10.3 10.2 15.1 10.2 10.6 11.9 8.8 9.0 14.2 16.7 16.3 22.2 12.7 21.5 25.1 21.3 22.0 22.7 23.0 26.1 26.7 20.3 15.0 21.8 27.6 28.8 12.3 19.1 24.4 30.5 45.7 18.9 42.8 12.0 19.9 22.0 11.5 23.9 16.7 25.7 24.9 24.4 24.0 27.6 23.5 42.6 15.8 26.3 12.3 22.2 26.8 16.1 14.7 8.9 24.6 14.6 9.3 18.2 11.4 18.4 11.9 12.0 9.1 18.7 38.2 12.4 18.1 21.3 28.3 13.0 13.7 13.9 18.0 18.6 13.3 28.8 15.6 20.2 25.9 9.5 14.1 12.2 10.5 11.6 9.6 11.5 14.3 14.9 9.2 9.6 11.8 1.7 21.0 18.1 18.0 14.7 8.5 7.5 10.3 8.0 9.7 8.0 9.0 10.6 9.1 10.6 8.4 10.2 14.2 6.3 6.4 6.1 20.2 8.2 0.9 3.3 4.6 8.6 5.1 4.3 3.4 5.0 7.2 3.7 0.0 0.0 10.4 6.7 3.4 5.9 7.4 14.5 10.4 7.2 7.0 3.6 11.4 20.6 3.8 12.2 8.0 5.6 5.8 17.7 11.0 4.2 3.2 9.7 8.4 30.8 3.7 2.0 8.9 3.1 13.7 6.2 6.2 1.8 12.2 10.1 4.7 10.3 24.6 35.9 4.0 13.3 8.6 7.0 1.3 4.7 5.8 4.4 4.8 13.1 6.0 6.8 7.7 4.4 5.3 1.3 7.3 6.5 7.5 5.3 2.0 SMARCB1 "BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1" ENSG00000099956 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1" Q12824 22 23786931-23838009 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Hypotrichosis, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009196, HPA018248, HPA019127" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center" "CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165" "unprognostic (2.15e-1)" "unprognostic (5.62e-2)" "unprognostic (6.60e-3)" "unprognostic (1.63e-2)" "unprognostic (4.01e-3)" "unprognostic (2.14e-1)" "prognostic unfavorable (6.52e-4)" "unprognostic (4.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.03e-2)" "unprognostic (2.10e-2)" "unprognostic (4.43e-3)" "prognostic favorable (1.14e-6)" "unprognostic (1.24e-1)" "unprognostic (4.58e-2)" "unprognostic (4.57e-2)" "unprognostic (7.04e-2)" 35.9 46.4 2.3 6.9 2.5 3.3 40.3 4.1 10.0 51.5 2.7 40.9 8.1 51.4 0.4 51.0 40.4 2.2 44.0 2.3 2.3 47.0 36.9 32.3 5.8 4.3 2.7 63.1 43.9 1.2 48.0 1.2 2.7 36.6 1.1 25.3 44.1 0.6 48.1 50.1 51.7 0.6 2.2 51.7 40.4 68.3 2.3 3.5 41.3 1.8 1.5 37.5 40.9 2.9 2.4 1.6 28.2 2.6 2.7 0.7 5.8 9.2 2.7 2.7 4.3 3.4 2.6 24.2 7.9 1.2 2.9 4.4 6.9 4.6 4.5 4.1 10.5 20.1 3.2 2.1 3.0 21.7 5.6 1.6 3.4 3.2 6.9 1.4 1.4 3.0 5.6 12.9 1.7 6.1 17.6 5.0 8.6 7.2 5.7 11.0 23.1 10.8 2.3 4.5 13.4 10.1 2.2 0.6 17.9 14.8 2.2 3.3 2.2 2.4 9.8 3.8 2.7 13.8 14.3 17.7 1.8 11.3 6.8 7.1 12.8 6.4 4.4 13.4 6.4 24.4 5.5 5.7 12.0 9.2 4.5 3.0 1.1 9.8 16.8 13.3 10.4 8.1 2.3 2.5 4.1 10.0 2.3 2.3 4.3 2.7 2.7 2.2 2.3 2.9 33.6 6.4 8.6 17.0 120.2 50.2 73.3 85.1 51.2 55.4 42.9 49.1 6.1 47.1 37.4 47.8 20.9 120.6 61.8 36.6 84.1 94.6 42.6 40.9 54.9 37.4 71.8 57.8 14.1 77.1 228.1 46.2 41.8 41.1 34.8 112.2 41.0 20.3 76.1 67.3 18.4 54.6 99.7 23.0 41.7 18.9 35.8 36.5 56.9 15.9 51.2 92.4 45.3 17.1 18.1 74.7 53.1 32.0 139.6 74.4 41.9 86.4 28.5 49.6 19.7 47.7 62.8 138.9 163.3 64.5 53.0 160.1 42.0 96.8 65.4 65.1 SMARCC2 "BAF170, CRACC2, Rsc8" ENSG00000139613 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2" Q8TAQ2 12 56162359-56189567 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004321, HPA021213, HPA061788" Supported Enhanced Nucleoplasm NA NA 11000 "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "CAB004321: AB_2286337, HPA021213: AB_1857275, HPA061788: AB_2684608" "unprognostic (7.51e-2)" "unprognostic (1.08e-2)" "unprognostic (9.31e-2)" "unprognostic (4.93e-2)" "unprognostic (1.62e-1)" "unprognostic (1.02e-1)" "unprognostic (1.43e-2)" "unprognostic (1.83e-1)" "unprognostic (1.71e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-1)" "unprognostic (1.04e-1)" "unprognostic (2.46e-1)" "unprognostic (1.35e-1)" "unprognostic (2.45e-1)" "unprognostic (6.74e-2)" "unprognostic (8.79e-2)" 36.6 33.5 48.1 23.8 52.1 23.5 38.5 48.7 56.3 43.8 19.9 39.3 27.7 42.9 22.8 30.5 40.8 23.3 26.4 49.6 50.9 31.6 19.8 29.7 29.5 44.2 43.8 51.9 32.6 35.5 32.4 25.3 40.2 34.8 23.4 39.2 37.2 33.5 46.7 36.5 34.5 28.4 40.2 31.9 33.0 32.8 49.1 39.0 49.8 30.5 28.7 39.1 37.4 51.6 49.3 74.9 77.2 56.4 47.2 48.9 32.4 42.6 45.3 50.3 48.4 43.5 59.5 71.4 40.0 50.0 47.7 54.8 49.9 42.9 45.1 54.3 47.6 112.2 51.6 27.8 25.6 53.4 79.8 46.4 31.5 47.6 23.7 91.3 65.4 54.7 65.5 57.2 48.1 52.1 90.4 56.0 26.4 39.0 50.4 53.5 62.0 55.0 38.6 63.4 56.6 59.0 72.8 49.4 20.6 40.3 84.3 49.3 56.1 42.5 51.7 38.4 31.8 54.8 41.9 48.4 44.3 35.5 46.9 15.4 8.5 21.0 11.4 10.2 12.3 8.6 8.2 8.6 7.3 9.4 6.0 7.6 7.9 8.3 13.9 6.0 8.6 11.6 48.1 52.1 48.7 56.3 49.6 50.9 44.2 43.8 40.2 40.2 49.1 51.6 40.8 67.3 43.5 40.1 40.9 20.5 43.2 24.5 62.6 59.3 26.6 28.8 25.7 34.3 40.6 42.3 39.6 20.4 39.0 17.9 7.9 25.4 1.6 24.3 42.8 38.5 22.7 51.9 39.5 18.0 11.9 40.2 33.6 36.3 65.1 56.3 33.9 17.3 16.6 38.7 37.5 22.3 32.6 20.6 20.7 7.8 69.0 29.3 19.6 23.4 36.0 42.3 70.0 33.2 23.4 22.7 17.1 55.3 44.6 32.2 19.8 17.3 25.0 66.0 19.7 47.9 42.3 45.5 31.7 55.9 22.6 13.3 49.9 36.6 21.4 37.7 SMARCD1 "BAF60A, CRACD1, Rsc6p" ENSG00000066117 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1" Q96GM5 12 50085200-50100707 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Chromatin regulator" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004101 Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Vesicles "HPA004101: AB_1080026" "unprognostic (1.88e-1)" "unprognostic (1.89e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-2)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" "prognostic unfavorable (2.53e-8)" "unprognostic (3.62e-2)" "unprognostic (1.44e-1)" "unprognostic (4.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.10e-2)" "unprognostic (1.20e-3)" "unprognostic (2.18e-1)" "unprognostic (3.45e-1)" "unprognostic (1.38e-1)" "unprognostic (5.04e-2)" 25.8 28.1 25.2 23.2 27.6 44.0 24.9 24.4 27.0 23.5 20.8 22.0 23.2 27.9 27.1 27.5 23.8 17.9 18.3 26.3 23.8 25.3 19.0 23.9 35.0 25.7 25.7 26.4 22.5 47.3 19.7 28.9 25.3 23.2 27.2 25.1 24.3 21.8 16.9 24.3 27.8 28.8 24.8 31.3 20.5 23.8 25.8 57.2 26.8 16.1 47.6 23.5 21.7 27.6 28.4 47.6 134.8 75.8 41.1 38.9 68.1 35.1 62.0 100.3 58.2 130.0 42.1 109.4 51.0 67.2 44.4 35.4 112.9 91.5 87.3 84.4 87.0 107.2 49.4 75.8 49.3 95.0 41.1 40.2 60.2 59.8 107.4 66.1 119.5 114.0 93.1 64.8 50.6 67.7 137.6 54.0 166.0 43.2 76.6 165.5 34.9 96.0 57.3 66.1 71.4 121.3 73.1 35.2 139.3 100.4 79.4 78.7 70.4 50.1 56.0 31.7 69.9 91.6 88.2 95.4 40.6 37.7 56.9 3.4 1.2 2.2 2.9 1.2 2.9 3.6 1.6 2.0 1.8 2.7 1.0 3.3 0.5 1.7 1.9 3.5 2.7 1.2 25.2 27.6 24.4 27.0 26.3 23.8 25.7 25.7 25.3 24.8 25.8 27.6 29.7 0.0 9.6 11.1 42.9 16.6 22.3 17.7 42.7 33.7 33.2 30.2 6.5 15.7 20.5 27.6 20.9 21.1 39.6 21.6 52.8 32.8 4.3 20.0 36.9 30.1 31.1 25.7 9.3 29.0 19.4 17.8 14.8 30.5 16.5 40.0 17.5 15.1 17.3 26.9 10.5 18.2 10.2 14.4 13.1 9.1 16.4 16.8 17.8 7.5 27.1 26.5 29.9 11.1 17.1 36.8 14.8 16.1 28.9 28.8 19.5 47.9 9.4 28.8 32.9 31.6 28.2 28.4 36.5 31.3 19.6 11.1 30.0 26.8 19.1 15.9 SMARCE1 BAF57 ENSG00000073584 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1" Q969G3 17 40624962-40648654 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" Neurogenesis "Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003916, CAB037318" Supported Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "CAB037318: AB_476780, HPA003916: AB_1857279" "unprognostic (7.91e-2)" "unprognostic (2.68e-2)" "unprognostic (2.09e-2)" "unprognostic (8.06e-3)" "unprognostic (1.87e-1)" "unprognostic (2.55e-2)" "unprognostic (4.48e-1)" "unprognostic (1.25e-2)" "unprognostic (2.20e-2)" "unprognostic (1.05e-1)" "unprognostic (2.53e-2)" "unprognostic (2.04e-1)" "unprognostic (9.80e-2)" "unprognostic (5.93e-2)" "unprognostic (7.63e-2)" "unprognostic (1.09e-1)" "unprognostic (1.27e-2)" 39.4 22.2 10.5 37.8 11.9 43.2 35.6 10.6 13.3 45.9 14.3 40.2 38.9 56.2 28.3 43.6 39.0 41.4 40.1 9.2 11.7 31.2 31.5 36.1 49.6 13.7 10.7 58.6 35.4 38.3 13.3 48.4 13.2 34.2 38.5 17.5 33.6 42.1 42.5 27.7 39.3 57.4 11.7 40.5 30.9 31.5 11.2 76.1 40.8 44.7 54.2 46.8 26.2 16.5 86.5 139.6 169.1 126.5 87.7 125.5 82.8 105.9 145.4 122.1 91.0 92.7 72.7 135.9 149.6 145.3 81.0 114.5 106.1 112.3 145.1 128.3 138.0 97.2 73.4 165.2 87.8 179.8 94.5 109.3 87.6 97.7 140.6 122.1 133.4 106.5 144.2 52.2 118.2 96.5 331.6 37.1 95.4 70.8 68.6 183.3 190.2 103.7 147.5 144.9 134.6 130.0 94.5 269.4 86.6 181.5 161.5 111.4 109.7 98.1 107.6 89.7 132.6 97.7 122.8 204.5 100.0 80.9 154.9 106.3 64.4 88.2 91.7 67.8 95.0 99.8 82.4 96.1 77.9 112.3 68.3 79.3 26.5 124.7 82.2 80.3 114.7 112.2 10.5 11.9 10.6 13.3 9.2 11.7 13.7 10.7 13.2 11.7 11.2 16.5 41.4 48.1 45.1 13.1 67.5 38.1 43.0 69.5 65.4 75.8 19.7 20.2 53.0 38.6 61.5 20.2 16.7 101.8 68.7 38.7 15.6 41.5 27.1 34.9 47.0 60.4 96.5 84.1 17.1 32.3 75.7 72.4 44.9 32.1 74.0 41.3 62.8 44.0 51.6 82.4 18.8 53.5 65.1 42.9 39.6 11.8 90.4 30.9 24.9 19.7 63.2 63.3 105.0 26.7 32.7 35.7 46.7 82.4 44.2 36.5 52.8 30.5 59.3 37.1 39.5 62.7 57.0 49.7 50.9 63.3 40.1 114.8 53.8 35.3 62.5 34.3 SMC1A "DXS423E, KIAA0178, SB1.8, SMC1L1, Smcb" ENSG00000072501 "Structural maintenance of chromosomes 1A" Q14683 X 53374149-53422728 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Cancer-related genes, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005499, CAB025404" Supported Enhanced Nucleoplasm NA NA 33000 "Cluster 27: Non-specific - Gene expression" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB025404: , HPA005499: AB_1080028" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (4.00e-2)" "unprognostic (5.76e-2)" "unprognostic (1.04e-1)" "unprognostic (9.89e-2)" "unprognostic (1.29e-3)" "unprognostic (1.89e-1)" "unprognostic (9.80e-3)" "unprognostic (9.49e-2)" "unprognostic (4.48e-2)" "unprognostic (6.55e-2)" "unprognostic (2.58e-1)" "unprognostic (4.18e-3)" "unprognostic (6.28e-2)" "unprognostic (2.89e-1)" "unprognostic (9.39e-2)" 16.6 11.8 8.7 28.4 11.7 30.3 17.2 15.0 9.5 13.8 9.6 20.0 18.6 21.0 8.0 17.1 16.7 11.5 15.6 7.8 9.5 16.3 18.8 16.0 34.4 10.2 10.7 19.1 14.4 25.8 6.3 18.2 10.7 14.0 18.4 21.0 15.1 13.0 17.9 18.1 15.9 22.9 8.7 20.1 15.7 7.8 11.3 58.1 16.8 18.8 29.9 15.5 12.4 13.9 110.0 115.1 92.4 76.1 32.4 35.4 51.5 68.0 37.0 76.4 59.4 71.6 60.5 115.8 54.1 40.7 105.2 78.9 162.9 92.6 85.1 91.7 176.0 94.3 133.9 51.1 15.4 134.9 120.9 20.6 23.3 86.0 52.8 19.4 67.5 68.7 144.7 64.7 58.6 69.2 122.0 40.8 139.9 47.8 55.6 117.2 165.5 100.1 34.4 69.4 92.8 83.5 176.9 84.4 33.5 122.8 87.9 54.0 45.7 63.3 68.0 65.1 62.2 45.8 77.9 91.9 39.1 152.1 64.1 2.7 6.8 4.5 7.3 8.5 7.6 5.4 5.8 6.7 8.4 5.8 5.2 6.3 2.7 4.6 12.4 4.6 5.7 6.7 8.7 11.7 15.0 9.5 7.8 9.5 10.2 10.7 10.7 8.7 11.3 13.9 40.7 44.8 39.9 16.0 45.6 24.1 37.0 27.7 28.5 46.6 30.7 27.4 63.5 27.1 47.4 20.2 27.1 43.2 57.7 49.6 7.9 31.6 10.5 46.5 62.6 41.7 19.9 70.7 12.0 27.1 61.4 37.2 29.0 44.0 35.4 42.7 18.9 54.1 47.6 60.6 14.2 43.5 22.4 41.1 27.6 7.6 37.9 51.5 23.2 24.4 55.2 38.1 59.8 16.6 30.2 33.1 23.6 36.1 61.2 40.7 29.0 24.6 47.1 48.4 39.5 49.5 71.0 54.5 51.2 39.8 24.4 48.4 47.9 34.0 51.4 32.0 SMC3 "BAM, bamacan, CSPG6, HCAP, SMC3L1" ENSG00000108055 "Structural maintenance of chromosomes 3" Q9UQE7 10 110567695-110606048 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Spermatocytes: 994.2;Spermatogonia: 799.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043206 Approved Supported Nucleoplasm NA NA 630000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "HPA043206: AB_2678362" "unprognostic (3.40e-1)" "unprognostic (1.73e-2)" "unprognostic (9.05e-2)" "unprognostic (3.00e-2)" "unprognostic (3.73e-2)" "unprognostic (8.89e-3)" "unprognostic (9.74e-3)" "unprognostic (8.06e-2)" "unprognostic (5.31e-2)" "unprognostic (6.32e-2)" "unprognostic (3.53e-2)" "unprognostic (1.17e-2)" "unprognostic (8.73e-3)" "unprognostic (7.22e-2)" "unprognostic (5.18e-2)" "unprognostic (7.95e-2)" "unprognostic (1.32e-1)" 19.5 13.3 9.0 18.7 10.9 43.9 19.1 18.5 11.7 18.5 11.7 18.3 15.5 20.3 15.7 19.2 16.5 11.1 12.9 8.6 10.2 14.0 15.3 14.5 25.2 10.2 9.4 25.7 19.6 20.0 14.2 20.7 10.4 14.0 16.7 27.6 16.2 15.2 21.1 20.6 19.4 16.9 9.6 18.6 14.7 38.1 9.5 39.2 16.5 14.1 24.3 15.5 17.8 12.7 73.1 44.5 95.4 67.8 30.7 26.3 40.9 57.7 56.7 51.9 50.7 56.4 59.7 94.2 24.5 38.6 40.0 56.5 68.7 35.0 78.6 77.3 60.1 76.5 56.2 51.2 30.8 109.8 56.6 21.1 28.0 57.4 89.5 48.5 38.8 31.7 61.7 70.4 45.4 38.1 85.2 58.3 66.1 38.6 35.1 71.1 171.5 51.4 32.4 31.7 53.7 61.8 62.0 17.7 48.6 61.8 28.5 53.1 40.1 41.6 65.5 47.6 84.4 40.9 38.8 99.6 37.5 103.9 34.8 20.7 6.1 15.8 9.6 8.4 12.1 11.0 11.3 10.6 6.8 11.0 11.3 11.2 6.5 12.6 7.6 8.7 14.5 6.2 9.0 10.9 18.5 11.7 8.6 10.2 10.2 9.4 10.4 9.6 9.5 12.7 74.9 80.1 62.0 16.6 73.5 60.5 53.2 64.1 34.7 81.3 44.3 49.9 64.5 47.1 64.4 55.2 75.0 119.6 94.3 29.8 25.4 96.9 56.9 52.0 65.0 74.9 40.7 104.6 26.2 45.6 111.4 66.0 20.9 49.0 56.3 124.9 40.4 31.9 59.1 60.6 29.2 40.7 54.9 37.9 42.5 34.6 115.2 49.8 37.4 19.7 96.1 54.9 98.9 33.2 43.4 53.0 70.1 114.0 65.0 44.7 70.7 30.3 68.3 78.9 184.1 102.0 110.6 994.2 799.1 48.1 64.5 49.1 80.9 112.7 51.9 37.5 SMG9 "C19orf61, FLJ12886" ENSG00000105771 "SMG9 nonsense mediated mRNA decay factor" Q9H0W8 19 43727983-43754962 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 103.2;Late spermatids: 329.5;Syncytiotrophoblasts: 95.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041763, HPA042096" Uncertain Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Mitochondria, Cytosol" "Plasma membrane" "HPA041763: AB_2677659, HPA042096: AB_2677845" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (7.41e-2)" "unprognostic (6.46e-2)" "unprognostic (2.71e-1)" "unprognostic (1.55e-2)" "prognostic unfavorable (2.15e-5)" "unprognostic (2.71e-1)" "unprognostic (4.11e-2)" "unprognostic (9.24e-3)" "unprognostic (3.88e-2)" "unprognostic (8.76e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (8.00e-2)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "prognostic favorable (8.09e-4)" 9.0 11.7 10.3 10.9 10.8 8.4 8.7 10.9 13.5 10.6 5.9 9.0 8.0 9.0 7.7 9.2 7.7 6.8 7.7 10.2 10.6 7.7 6.6 10.0 13.0 13.1 11.6 7.8 5.8 8.8 9.4 10.1 13.6 11.5 6.2 5.9 12.0 6.9 7.5 10.7 10.0 8.1 9.5 13.5 8.7 33.8 11.6 11.8 8.3 7.1 12.0 10.0 9.9 14.9 25.3 27.2 19.5 12.5 13.4 18.9 13.1 35.1 20.8 38.4 28.7 19.4 32.5 27.4 16.9 24.1 13.2 10.7 22.9 19.7 24.9 21.1 13.2 49.2 20.5 12.9 15.6 37.4 25.9 10.1 16.6 27.9 29.6 32.1 15.8 25.0 37.7 23.6 18.0 17.9 39.9 10.6 9.4 48.0 18.2 21.2 16.1 12.3 20.4 20.4 32.4 15.9 36.7 27.4 21.3 15.4 16.6 20.5 19.2 59.7 35.4 22.3 27.1 11.5 26.8 33.4 17.9 28.4 49.7 1.0 5.3 3.3 5.1 7.7 4.5 7.4 5.1 4.3 6.9 5.3 6.7 4.5 1.3 4.2 11.7 6.1 4.1 11.3 10.3 10.8 10.9 13.5 10.2 10.6 13.1 11.6 13.6 9.5 11.6 14.9 7.7 32.1 8.3 20.9 13.7 9.3 15.0 16.8 11.4 13.2 10.0 11.0 4.4 4.3 9.0 9.2 4.2 49.5 11.3 9.5 1.9 12.2 103.2 5.5 7.0 12.0 4.2 7.8 19.5 8.7 15.8 11.4 15.8 8.9 9.5 12.1 11.0 3.3 21.4 13.5 23.0 11.3 8.2 10.3 9.2 329.5 13.1 12.1 10.6 11.2 16.2 6.0 4.1 16.1 29.6 13.6 9.2 12.0 11.2 15.9 8.5 6.8 8.4 9.2 6.6 11.2 8.5 42.6 16.2 8.4 7.1 95.4 9.3 11.8 12.2 11.1 SMOC1 ENSG00000198732 "SPARC related modular calcium binding 1" Q9H4F8 14 69854131-70032366 "Disease related genes, Human disease related genes, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.2;liver: 67.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 104.4;Oligodendrocyte precursor cells: 372.4;Oligodendrocytes: 81.1;Peritubular cells: 133.2" "Cancer enhanced" "Detected in many" "glioma: 27.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cell line enhanced" "Detected in some" "AF22: 50.3;HeLa: 122.6;HSkMC: 38.3;SiHa: 72.1;SK-BR-3: 30.6;U-266/70: 42.3;U-87 MG: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004153, CAB034427" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 140000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "CAB034427: AB_2193382, HPA004153: AB_1080035" "unprognostic (3.31e-1)" "unprognostic (2.17e-3)" "unprognostic (8.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.89e-2)" "unprognostic (4.04e-1)" "unprognostic (6.75e-3)" "unprognostic (2.09e-3)" "unprognostic (4.76e-2)" "unprognostic (2.80e-2)" "unprognostic (5.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.09e-2)" "unprognostic (3.92e-1)" "unprognostic (2.57e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" 15.9 10.3 29.2 0.5 30.3 0.1 6.2 53.2 29.1 9.4 17.5 1.3 1.9 2.2 7.7 0.3 6.6 0.5 8.3 27.9 31.6 3.0 67.9 0.6 0.9 38.4 38.8 1.4 10.3 0.3 4.4 8.0 36.8 33.4 1.0 2.4 5.8 38.8 12.7 2.4 1.4 1.0 41.2 27.2 3.8 35.7 29.6 0.4 4.2 2.7 0.5 1.3 6.3 52.8 0.0 3.3 50.3 0.0 9.8 6.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 2.9 0.0 0.0 20.4 0.0 122.6 17.4 0.1 0.0 0.0 38.3 11.9 1.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.0 0.2 72.1 30.6 0.0 0.3 0.0 0.0 0.4 0.3 2.9 0.0 0.0 42.3 0.0 0.0 51.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 29.2 30.3 53.2 29.1 27.9 31.6 38.4 38.8 36.8 41.2 29.6 52.8 0.3 0.0 0.0 12.1 2.5 0.3 0.0 0.7 0.0 2.1 1.3 3.8 2.0 7.2 0.1 0.0 16.7 24.2 4.0 0.0 0.0 0.3 4.7 11.9 0.6 2.9 15.6 0.0 1.0 2.3 0.8 6.0 3.6 1.5 0.0 1.4 3.3 104.4 2.8 0.0 13.5 0.1 14.2 2.5 0.4 19.0 7.8 0.3 0.0 1.0 0.1 0.3 0.0 372.4 81.1 3.7 0.1 133.2 12.4 0.0 0.0 0.0 1.1 0.3 0.0 0.7 2.3 2.1 3.9 0.0 0.4 40.2 0.4 0.4 0.0 0.1 SMS "MRSR, SPMSY, SpS, SRS" ENSG00000102172 "Spermine synthase" P52788 X 21940709-21994837 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Polyamine biosynthesis" Transferase "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 644.3;Distal tubular cells: 608.4;Syncytiotrophoblasts: 869.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029849, HPA029852" Approved Approved "Nuclear bodies,Cytosol" No No 16000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear bodies" Cytosol "HPA029849: AB_10602072, HPA029852: AB_10611521" "unprognostic (2.51e-2)" "unprognostic (2.91e-1)" "unprognostic (1.89e-2)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (7.49e-4)" "prognostic unfavorable (7.79e-8)" "unprognostic (1.02e-2)" "unprognostic (2.72e-1)" "unprognostic (3.18e-3)" "unprognostic (3.95e-3)" "unprognostic (2.45e-1)" "prognostic unfavorable (7.85e-5)" "unprognostic (2.70e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" "unprognostic (8.50e-2)" 29.7 94.3 52.0 34.7 53.5 50.8 49.6 56.0 61.9 42.7 43.7 52.0 54.9 44.7 63.6 30.6 28.6 40.5 53.0 53.9 50.2 119.9 44.3 36.2 47.8 48.6 46.7 91.2 24.1 28.0 31.5 114.2 49.1 136.0 50.4 49.5 39.7 42.2 34.6 21.4 50.9 39.6 47.0 41.3 39.3 30.2 53.9 50.7 55.3 32.5 47.3 55.1 32.0 49.6 664.3 161.2 265.3 107.1 71.9 121.4 86.3 174.6 102.6 261.7 249.1 204.0 213.0 239.5 59.8 180.0 722.9 142.2 265.5 318.2 508.2 111.0 128.6 124.4 201.0 145.5 129.4 242.2 103.8 76.8 93.7 266.4 497.2 189.2 254.5 93.6 270.6 32.7 366.7 139.2 181.3 244.1 474.9 149.0 244.3 176.0 188.5 182.9 354.3 90.1 131.4 105.7 143.1 181.8 489.1 687.6 163.9 101.3 232.3 194.4 193.6 405.0 294.5 23.8 52.6 142.2 378.4 107.5 275.6 9.1 57.5 102.5 18.9 59.9 23.7 34.6 29.6 33.3 51.1 22.0 19.1 22.8 55.7 31.4 73.9 10.7 55.4 37.3 52.0 53.5 56.0 61.9 53.9 50.2 48.6 46.7 49.1 47.0 53.9 49.6 43.4 25.6 21.9 33.6 61.5 65.9 203.0 206.1 42.1 35.7 116.2 66.3 36.1 81.5 115.0 110.3 12.5 644.3 46.7 61.2 608.4 246.3 1.9 126.4 70.4 61.9 58.8 95.2 45.6 152.3 313.1 86.6 57.6 215.9 40.5 249.5 59.6 49.8 364.7 21.9 40.2 103.6 146.5 157.3 200.3 7.1 95.4 153.1 92.5 21.5 250.7 46.8 48.4 22.1 8.1 165.6 63.9 103.4 45.6 276.2 137.0 466.7 78.9 43.2 65.7 76.6 114.2 6.0 181.3 54.1 50.6 869.6 63.7 271.2 119.1 153.1 SNAP29 "CEDNIK, SNAP-29" ENSG00000099940 "Synaptosome associated protein 29" O95721 22 20859007-20891214 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Protein transport, Transport" "Ichthyosis, Neuropathy, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 524.1;Late spermatids: 191.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 220.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031823, CAB037092, HPA056492" Supported Supported Nucleoplasm,Cytosol NA NA 110000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol Nucleoplasm "CAB037092: AB_477491, HPA031823: AB_10602407, HPA056492: AB_2683151" "unprognostic (1.76e-1)" "prognostic favorable (6.99e-4)" "unprognostic (3.72e-3)" "unprognostic (3.26e-2)" "unprognostic (7.83e-3)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (2.05e-2)" "unprognostic (1.34e-2)" "unprognostic (2.60e-2)" "unprognostic (3.68e-2)" "unprognostic (6.85e-2)" "unprognostic (1.22e-1)" "unprognostic (2.52e-1)" "unprognostic (1.45e-1)" "unprognostic (4.51e-3)" "unprognostic (6.08e-2)" 18.3 18.0 10.8 17.1 11.5 18.9 15.9 12.8 18.0 15.3 11.7 19.9 17.4 14.5 11.1 23.1 12.8 13.7 18.9 12.0 11.4 16.8 35.8 13.9 17.0 12.6 11.7 13.6 17.3 18.7 11.0 19.1 12.4 13.5 17.8 14.4 15.8 14.1 31.2 19.0 16.6 18.1 11.2 16.8 18.6 56.5 11.0 24.1 12.3 27.4 19.7 15.6 15.7 12.5 48.4 19.4 27.1 22.3 30.0 43.5 35.0 44.8 40.3 49.5 49.5 26.8 16.7 30.1 27.9 42.2 50.0 27.8 35.8 30.4 53.2 43.5 27.3 50.0 20.9 29.2 42.7 44.6 38.8 34.6 42.2 51.9 37.2 34.0 35.1 25.5 220.8 41.5 46.2 33.1 40.7 42.9 8.9 55.9 20.2 38.9 60.6 12.1 29.1 25.5 22.0 26.2 48.0 29.9 51.0 33.3 46.8 35.3 30.7 50.1 45.5 34.6 35.6 42.4 74.0 55.3 37.5 29.8 36.7 49.0 43.7 52.4 21.7 61.5 22.7 23.7 21.2 23.7 38.0 22.6 19.3 19.8 49.0 60.0 77.9 43.6 34.5 34.6 10.8 11.5 12.8 18.0 12.0 11.4 12.6 11.7 12.4 11.2 11.0 12.5 24.4 12.8 29.0 8.8 19.0 16.7 24.5 34.7 17.6 12.4 26.4 22.5 22.5 21.5 22.9 23.9 12.5 80.1 35.9 40.0 43.0 40.3 524.1 26.3 28.2 30.1 22.1 36.4 9.6 50.0 146.0 28.4 26.5 22.3 29.2 25.0 29.6 46.5 74.4 20.2 7.2 27.6 32.6 49.4 23.1 191.7 33.2 46.7 35.6 2.8 51.4 30.6 48.4 10.6 12.1 59.4 21.4 36.5 44.1 26.7 38.8 36.8 37.4 13.2 39.5 21.9 27.9 113.5 81.1 28.2 15.5 98.2 26.5 70.3 25.3 29.7 SNRPB "COD, Sm-B/B', SmB/SmB', snRNP-B, SNRPB1" ENSG00000125835 "Small nuclear ribonucleoprotein polypeptides B and B1" P14678 20 2461634-2470853 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA003482, CAB009610, HPA067842" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "CAB009610: AB_2193859, HPA003482: AB_1857337, HPA067842: AB_2685909" "unprognostic (2.33e-1)" "unprognostic (3.14e-2)" "unprognostic (5.64e-2)" "unprognostic (2.73e-2)" "unprognostic (9.47e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (1.07e-5)" "unprognostic (5.11e-2)" "unprognostic (3.66e-1)" "unprognostic (4.66e-2)" "unprognostic (7.30e-2)" "unprognostic (4.20e-2)" "unprognostic (2.21e-1)" "unprognostic (2.79e-1)" "unprognostic (1.13e-1)" "unprognostic (9.18e-2)" "unprognostic (9.47e-2)" 113.4 110.5 45.0 110.7 45.1 345.4 111.6 50.8 54.5 103.7 48.5 108.1 102.6 119.4 66.7 177.1 93.7 62.7 90.1 46.7 47.1 103.6 91.9 111.7 166.7 47.7 45.1 93.8 78.0 83.1 72.5 82.9 47.4 87.9 86.5 25.0 99.7 62.4 112.6 148.5 109.2 85.9 48.6 139.0 100.7 83.2 46.8 168.9 77.1 59.9 154.0 109.3 108.9 50.4 782.5 1063.7 376.7 340.4 83.8 149.1 418.7 334.6 259.8 693.8 556.2 1209.6 555.7 588.8 210.6 203.2 556.7 567.8 370.7 636.2 350.3 239.7 658.6 400.5 190.0 1148.0 290.0 560.3 236.6 171.3 237.9 564.0 252.6 132.2 389.0 491.1 561.0 414.6 288.7 543.0 897.1 916.2 825.2 405.8 520.8 531.3 379.0 711.4 266.8 407.8 405.6 442.7 414.5 554.3 503.2 162.8 524.5 612.9 266.7 404.4 340.9 360.8 764.8 345.5 938.8 877.1 137.7 623.8 419.5 167.9 166.7 133.0 202.8 210.9 170.5 210.7 178.0 179.5 226.7 210.6 144.2 167.5 87.8 166.0 221.6 237.4 241.5 266.0 45.0 45.1 50.8 54.5 46.7 47.1 47.7 45.1 47.4 48.6 46.8 50.4 197.0 44.8 69.1 4.6 206.9 478.6 335.2 309.4 150.2 46.8 156.8 151.8 17.9 112.9 167.3 93.8 12.5 365.2 251.9 163.6 144.8 347.3 17.1 98.3 143.0 202.9 142.0 170.0 6.8 295.8 647.8 155.4 89.2 128.4 144.5 215.0 83.2 60.8 294.8 30.3 6.3 239.4 203.4 102.7 308.3 20.4 159.1 158.0 190.3 6.5 189.5 68.9 265.7 6.0 8.5 404.6 171.9 123.8 176.9 421.8 119.3 143.6 98.9 57.5 157.8 169.6 228.5 329.6 308.3 181.5 423.1 373.4 210.1 306.7 293.5 433.2 SNX10 ENSG00000086300 "Sorting nexin 10" Q9Y5X0 7 26291862-26374383 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 285.7;Hofbauer cells: 148.7;Kupffer cells: 215.5;Macrophages: 166.5;monocytes: 152.3;Muller glia cells: 310.5;Proximal tubular cells: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 336.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 103.1;U-937: 87.3;WM-115: 297.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015605, HPA064782" Approved Supported Nucleoplasm,Nucleoli,Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Microtubules" Nucleoli "HPA015605: AB_1857342, HPA064782: AB_2685349" "unprognostic (6.42e-2)" "unprognostic (2.72e-3)" "unprognostic (2.45e-1)" "unprognostic (7.62e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.92e-2)" "unprognostic (2.48e-3)" "unprognostic (4.51e-2)" "unprognostic (4.87e-1)" "unprognostic (9.36e-2)" "unprognostic (1.59e-1)" "unprognostic (2.56e-1)" "prognostic unfavorable (8.06e-5)" "unprognostic (1.12e-2)" "unprognostic (3.21e-1)" "unprognostic (8.59e-2)" "unprognostic (1.50e-1)" 23.7 14.5 26.4 34.7 27.8 42.1 11.0 17.6 45.9 4.5 6.1 5.6 4.1 9.0 1.1 2.9 3.0 8.8 1.8 30.2 42.2 37.8 69.1 41.2 36.9 29.1 28.2 1.1 7.8 1.3 4.7 10.9 40.3 3.5 6.4 47.1 1.7 2.1 1.0 1.4 6.2 9.5 18.6 42.1 3.9 5.1 32.0 15.8 2.9 2.7 24.8 10.9 1.6 26.8 55.8 5.0 0.2 10.1 0.1 0.0 57.8 0.0 3.9 0.1 0.0 0.5 18.4 24.0 41.4 0.0 36.2 1.7 13.5 3.6 0.0 33.3 12.4 2.5 0.4 36.3 0.1 52.2 8.9 0.6 5.4 0.0 4.2 0.1 0.8 30.7 1.5 0.3 0.0 9.7 22.2 54.3 15.3 0.9 5.1 0.1 0.1 1.3 103.1 12.0 22.5 7.1 11.7 8.5 62.7 18.1 15.2 72.6 0.3 0.1 12.2 0.2 13.7 17.9 15.5 16.4 0.5 87.3 297.4 55.9 144.7 3.7 18.6 158.5 18.2 82.3 13.2 16.4 101.2 71.7 6.9 12.0 336.7 47.7 162.5 37.0 29.6 70.0 26.4 27.8 17.6 45.9 30.2 42.2 29.1 28.2 40.3 18.6 32.0 26.8 3.3 3.2 14.7 6.8 63.4 5.4 1.2 0.7 1.8 20.3 17.6 9.5 1.8 34.3 4.4 23.9 2.1 14.9 18.6 2.5 285.7 66.0 1.3 2.1 40.7 7.6 9.5 19.1 63.1 27.1 111.8 3.4 0.0 2.3 31.1 2.9 2.2 109.8 148.7 35.3 53.4 3.3 0.0 215.5 130.3 2.1 1.2 166.5 8.8 19.7 152.3 310.5 33.0 7.1 8.5 14.1 1.5 0.0 8.0 4.4 4.5 204.9 0.8 23.2 0.0 0.7 4.7 7.1 29.5 0.8 3.0 28.7 31.6 0.9 8.7 1.3 SON "BASS1, C21orf50, DBP-5, FLJ21099, FLJ33914, KIAA1019, NREBP" ENSG00000159140 "SON DNA and RNA binding protein" P18583 21 33543038-33577481 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, mRNA processing, mRNA splicing" "DNA-binding, RNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023535, HPA031755, HPA031756" Supported Enhanced "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" "HPA023535: AB_1857362, HPA031755: AB_2674029, HPA031756: AB_2674030" "unprognostic (1.58e-2)" "unprognostic (2.08e-1)" "unprognostic (4.69e-1)" "unprognostic (2.30e-1)" "unprognostic (5.63e-2)" "unprognostic (2.75e-1)" "unprognostic (4.22e-2)" "unprognostic (2.38e-1)" "unprognostic (1.05e-1)" "unprognostic (2.31e-2)" "unprognostic (2.02e-1)" "unprognostic (1.24e-1)" "unprognostic (9.75e-2)" "unprognostic (4.18e-1)" "unprognostic (9.20e-2)" "unprognostic (1.19e-1)" "unprognostic (2.54e-1)" 69.1 62.5 45.6 57.8 52.1 161.9 65.0 56.4 58.6 59.4 71.9 64.1 44.9 66.9 61.5 60.7 68.5 43.2 60.3 43.7 45.7 49.4 60.3 65.2 81.0 49.8 46.8 76.7 63.4 92.8 63.9 60.9 51.3 61.2 56.4 91.8 64.3 52.6 89.4 64.1 67.8 51.1 47.6 71.5 66.8 48.0 47.8 92.8 64.4 53.8 76.2 62.9 55.9 65.8 105.7 59.7 126.1 72.7 108.1 98.3 89.2 77.2 88.1 73.0 69.6 89.5 75.2 163.8 45.9 114.8 86.6 76.4 152.4 113.0 109.7 85.4 77.9 220.0 78.2 111.3 79.3 215.0 110.8 100.6 128.7 88.0 124.5 91.3 110.1 91.2 172.9 150.9 101.1 101.6 121.0 112.9 136.0 108.5 60.7 121.5 133.8 118.1 109.7 102.1 84.1 77.6 124.2 100.3 91.3 103.6 93.6 128.3 116.0 83.4 73.1 66.6 87.0 144.8 143.2 193.9 84.7 172.3 78.9 33.7 20.3 28.7 20.7 18.4 20.8 30.4 22.9 22.1 15.8 28.2 22.7 22.3 37.4 22.3 24.5 38.5 22.1 15.8 45.6 52.1 56.4 58.6 43.7 45.7 49.8 46.8 51.3 47.6 47.8 65.8 374.1 410.3 298.2 201.4 355.2 433.1 312.2 310.6 250.4 389.7 213.1 219.2 351.5 320.3 298.0 301.6 221.0 224.1 423.2 276.8 193.7 209.7 97.0 296.9 412.2 342.1 186.8 375.8 93.1 207.3 164.7 333.4 208.0 335.8 418.2 216.1 304.8 344.6 170.1 455.9 105.8 256.0 219.7 237.2 307.4 66.0 393.9 261.0 218.7 146.1 256.8 335.7 347.1 131.7 162.3 190.0 217.2 393.4 294.4 250.7 198.0 225.7 288.3 372.0 381.3 505.0 399.2 470.1 334.6 197.8 394.2 327.1 378.2 183.2 246.3 226.5 SOS1 "GF1, GINGF, HGF" ENSG00000115904 "SOS Ras/Rac guanine nucleotide exchange factor 1" Q07889 2 38981549-39124345 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 226.6;Inhibitory neurons: 224.0;Microglial cells: 161.1;Oligodendrocyte precursor cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HMC-1: 134.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005396 Uncertain Approved Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB005396: AB_2270724" "unprognostic (6.68e-2)" "unprognostic (2.12e-2)" "unprognostic (1.01e-1)" "unprognostic (4.14e-3)" "unprognostic (4.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.74e-3)" "unprognostic (4.55e-2)" "unprognostic (1.10e-1)" "unprognostic (4.13e-2)" "unprognostic (1.24e-2)" "unprognostic (3.18e-2)" "unprognostic (1.38e-2)" "unprognostic (8.96e-3)" "unprognostic (7.61e-2)" "unprognostic (5.59e-2)" "unprognostic (1.33e-2)" 17.5 8.4 8.2 14.8 10.2 10.8 9.8 14.1 10.3 13.1 6.8 11.0 14.7 14.3 10.3 12.3 11.2 13.5 9.5 9.7 10.8 11.0 11.9 11.0 16.9 9.5 10.2 20.1 9.1 17.1 0.1 17.0 9.5 13.4 12.9 13.2 9.0 12.2 13.7 9.4 15.6 13.8 6.7 12.5 11.5 10.3 8.7 15.4 15.1 16.4 17.8 13.5 0.1 10.6 24.8 15.1 22.8 16.2 29.1 35.0 23.8 15.3 18.7 12.0 11.4 16.3 14.6 35.8 10.3 20.1 18.5 14.4 26.9 13.9 22.1 36.3 11.9 55.5 12.8 22.0 11.8 17.9 134.9 21.6 20.5 16.3 15.8 19.5 18.9 8.1 23.9 16.4 15.4 13.5 19.4 15.8 14.3 30.4 10.4 21.5 20.5 10.5 12.1 19.8 22.0 22.0 18.3 32.3 18.2 18.5 10.4 9.3 21.5 19.8 16.0 15.7 15.4 19.3 20.9 18.4 15.8 17.3 12.0 0.0 0.5 1.4 1.3 0.7 1.9 1.6 1.3 1.4 0.4 1.0 1.5 1.4 0.6 2.7 0.9 0.6 0.9 0.4 8.2 10.2 14.1 10.3 9.7 10.8 9.5 10.2 9.5 6.7 8.7 10.6 72.3 16.0 31.2 120.5 20.9 20.8 15.5 10.9 19.9 19.0 18.4 16.9 33.9 18.6 17.8 9.2 10.4 10.2 27.6 19.5 1.9 11.0 64.9 30.0 36.6 43.2 12.0 12.8 226.6 11.9 8.4 22.9 21.4 34.0 3.8 30.0 12.8 18.6 10.3 8.4 224.0 16.9 26.4 19.1 13.2 11.4 22.7 19.9 7.2 161.1 19.6 15.1 26.8 173.4 125.2 14.2 14.6 21.8 37.5 25.3 28.0 12.8 20.4 11.2 6.6 27.1 22.7 11.3 7.0 17.1 25.3 10.4 33.2 18.4 17.0 28.4 SOS2 ENSG00000100485 "SOS Ras/Rho guanine nucleotide exchange factor 2" Q07890 14 50117130-50231578 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004577, HPA047368, HPA052689" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Vesicles "CAB004577: AB_628270, HPA047368: AB_2680014, HPA052689: AB_2681917" "unprognostic (7.99e-2)" "unprognostic (6.17e-2)" "unprognostic (7.80e-2)" "unprognostic (4.93e-2)" "unprognostic (2.81e-2)" "unprognostic (7.64e-2)" "unprognostic (1.56e-1)" "unprognostic (3.08e-1)" "unprognostic (2.01e-1)" "unprognostic (3.88e-1)" "unprognostic (9.99e-2)" "unprognostic (8.21e-2)" "prognostic favorable (8.48e-8)" "unprognostic (2.47e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (6.57e-2)" 23.8 14.9 15.3 15.3 21.4 39.5 17.9 18.2 19.5 14.3 13.5 17.4 21.5 15.2 22.4 16.4 12.7 12.9 21.5 14.0 16.8 24.5 13.2 15.8 14.4 19.7 18.6 15.3 15.9 39.3 9.1 17.0 19.1 15.4 17.3 14.0 14.5 18.7 57.6 17.9 24.5 18.0 16.8 17.8 13.7 27.9 19.6 16.5 25.1 63.8 13.5 14.8 10.5 23.9 15.3 11.1 22.1 14.9 16.6 18.0 10.4 13.5 14.8 10.0 12.5 4.9 19.8 16.0 11.9 17.3 17.3 13.8 12.1 10.2 17.7 26.9 4.4 16.1 8.5 8.5 18.3 19.1 16.6 18.8 24.6 9.3 21.6 25.2 21.8 13.1 12.5 39.0 24.2 12.7 15.9 15.1 6.9 11.4 9.6 17.0 30.8 12.1 16.1 14.4 16.0 18.7 15.0 17.5 17.8 15.9 19.4 23.0 24.1 27.3 17.8 12.5 8.9 27.3 31.7 19.6 7.1 10.5 16.4 8.0 1.1 2.8 1.1 0.9 0.9 0.6 0.7 0.8 0.8 0.7 0.8 0.7 4.6 1.7 2.0 1.4 0.0 0.4 15.3 21.4 18.2 19.5 14.0 16.8 19.7 18.6 19.1 16.8 19.6 23.9 34.1 9.6 26.3 59.4 18.4 35.7 20.9 10.5 10.2 17.2 23.8 15.6 43.7 17.2 18.2 18.4 16.7 8.2 46.3 36.0 7.9 11.3 17.0 18.7 30.4 23.5 20.4 6.3 71.5 10.7 8.0 22.2 12.8 29.8 20.3 37.4 22.9 13.8 8.8 25.2 89.6 18.5 12.2 33.3 17.5 8.6 12.5 29.0 17.8 80.6 29.0 17.6 21.6 100.5 104.8 14.5 24.6 13.5 28.6 27.3 28.6 15.8 14.3 22.5 19.7 43.4 30.8 54.3 12.3 17.7 39.6 13.0 24.2 17.4 14.9 30.6 SOST "DAND6, VBCH" ENSG00000167941 Sclerostin Q9BQB4 17 43753738-43758791 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" Heparin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "kidney: 13.3" "Cell type enhanced" "Detected in some" "B-cells: 1.4;Collecting duct cells: 1.8" "Cancer enhanced" "Detected in some" "lung cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HaCaT: 5.2;SuSa: 3.0" "Group enriched" "Detected in some" 11 "basal ganglia: 1.7;cerebellum: 1.0" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA 16000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.26e-1)" "unprognostic (4.06e-2)" "unprognostic (6.57e-2)" "unprognostic (2.55e-3)" "unprognostic (3.37e-1)" "unprognostic (4.67e-2)" "unprognostic (1.16e-1)" "unprognostic (8.35e-2)" "unprognostic (1.38e-2)" "unprognostic (1.20e-1)" "unprognostic (8.92e-2)" "unprognostic (1.56e-1)" "unprognostic (7.90e-2)" 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 13.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 SOX10 "DOM, WS2E, WS4" ENSG00000100146 "SRY-box transcription factor 10" P56693 22 37970686-37987422 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Deafness, Disease variant, Hirschsprung disease, Kallmann syndrome, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 194.9;salivary gland: 114.3" "Group enriched" "Detected in some" 14 "Breast glandular cells: 32.3;Breast myoepithelial cells: 47.8;Melanocytes: 35.6;Oligodendrocyte precursor cells: 61.3;Oligodendrocytes: 59.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 510 "SK-MEL-30: 313.9;WM-115: 432.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003171, HPA068898" Enhanced Supported Nucleoplasm Yes NA "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "CAB003171: AB_2195374, HPA068898: AB_2686054" 2.9 2.7 76.9 2.5 133.7 0.1 21.7 103.1 102.8 11.8 24.9 26.6 1.5 0.8 1.2 2.7 2.5 2.2 8.8 82.7 89.0 0.5 0.5 0.1 0.0 134.7 114.0 1.2 0.8 0.0 1.8 0.0 123.3 6.8 2.6 0.5 114.3 5.8 0.6 17.0 7.1 1.9 87.3 0.3 6.1 2.7 114.2 0.0 0.9 1.5 0.0 8.4 9.5 194.9 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 313.9 0.0 0.1 0.4 0.0 0.2 0.2 0.0 0.2 0.0 0.3 0.1 0.7 0.0 432.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.9 133.7 103.1 102.8 82.7 89.0 134.7 114.0 123.3 87.3 114.2 194.9 0.3 0.0 0.0 0.0 0.1 3.2 0.1 0.0 0.0 0.0 32.3 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.4 0.9 0.1 35.6 0.0 0.0 0.0 0.0 61.3 59.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.7 0.0 0.9 0.0 0.2 0.0 0.0 0.0 SOX11 ENSG00000176887 "SRY-box transcription factor 11" P35716 2 5692384-5701385 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 5.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 6.4;Breast myoepithelial cells: 8.6;Cardiomyocytes: 13.9;Inhibitory neurons: 8.4;Oligodendrocyte precursor cells: 21.6;Skeletal myocytes: 38.8" "Cancer enhanced" "Detected in many" "glioma: 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 47.2;NTERA-2: 23.6;REH: 17.9;RH-30: 18.2;SCLC-21H: 29.1;SH-SY5Y: 44.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000448, HPA000536, CAB056152, CAB056153" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB056152: AB_2665567, CAB056153: AB_2665568, HPA000448: , HPA000536: AB_1080060" "unprognostic (2.17e-2)" "unprognostic (2.02e-2)" "unprognostic (1.44e-2)" "unprognostic (7.35e-6)" "unprognostic (2.79e-1)" "unprognostic (1.19e-1)" "unprognostic (4.04e-8)" "unprognostic (2.79e-2)" "unprognostic (7.27e-2)" "unprognostic (3.17e-1)" "unprognostic (3.35e-3)" "unprognostic (2.42e-1)" "unprognostic (8.45e-8)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (5.50e-3)" "unprognostic (7.47e-2)" 0.0 0.0 2.3 0.0 2.8 0.0 0.0 1.3 1.9 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 5.0 0.0 0.0 0.0 0.0 2.5 2.9 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.2 3.2 0.1 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.0 47.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 1.5 0.0 2.3 0.0 0.0 4.4 0.0 0.0 0.0 23.6 0.0 0.0 17.9 18.2 0.7 0.0 0.0 29.1 44.0 0.0 0.3 0.0 8.2 0.0 0.0 0.0 0.6 0.2 0.0 0.0 3.3 0.6 1.2 0.0 0.0 11.1 0.7 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.1 2.3 2.8 1.3 1.9 1.3 5.0 2.5 2.9 2.0 3.2 4.6 3.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.1 6.4 8.6 13.9 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 5.7 0.9 0.0 0.8 1.2 0.0 0.0 0.4 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 1.0 0.0 0.5 0.0 21.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 38.8 1.1 0.0 0.2 0.0 0.0 0.3 0.1 0.1 0.0 0.0 SOX18 ENSG00000203883 "SRY-box transcription factor 18" P35713 20 64047582-64049639 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 78.4" "Group enriched" "Detected in many" 9 "Adipocytes: 370.9;Endothelial cells: 212.4;Hepatic stellate cells: 306.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 20.8;NB-4: 35.8;REH: 8.5;TIME: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073703 Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA073703: AB_2686628" "unprognostic (2.51e-1)" "unprognostic (3.23e-1)" "unprognostic (9.98e-3)" "unprognostic (6.30e-2)" "unprognostic (1.07e-1)" "unprognostic (2.88e-2)" "unprognostic (2.71e-2)" "unprognostic (4.35e-3)" "unprognostic (1.62e-1)" "unprognostic (3.45e-2)" "unprognostic (1.33e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-3)" "unprognostic (9.63e-3)" "unprognostic (1.41e-1)" "unprognostic (2.46e-1)" "unprognostic (5.40e-2)" 51.8 14.3 8.9 3.1 6.4 0.0 43.1 6.5 6.3 19.5 1.7 16.3 3.1 38.4 0.3 12.0 29.2 3.7 78.4 4.4 5.5 21.4 5.2 29.1 3.1 10.1 8.0 8.0 8.2 1.3 6.6 5.5 9.5 17.6 0.4 0.0 12.6 1.3 13.9 12.2 17.0 1.5 6.7 22.5 15.6 5.6 9.9 0.8 29.0 3.8 0.5 19.7 21.9 5.4 0.0 0.3 0.0 5.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 5.0 0.0 0.0 0.2 0.3 0.0 0.0 0.5 1.0 0.0 3.0 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 20.8 0.0 3.7 0.0 0.0 0.7 0.0 35.8 0.1 0.0 0.3 8.5 0.0 0.6 0.0 1.4 0.6 0.6 0.3 0.0 0.5 0.0 0.5 1.8 9.6 0.1 2.6 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 6.4 6.5 6.3 4.4 5.5 10.1 8.0 9.5 6.7 9.9 5.4 370.9 0.0 0.6 0.3 3.7 1.0 0.2 0.0 2.2 0.9 1.9 3.0 8.8 1.5 0.0 1.8 0.0 0.0 1.6 0.1 0.0 0.3 22.1 1.0 11.9 212.4 0.0 2.7 0.0 0.0 0.0 2.5 0.0 0.7 4.5 0.0 306.6 0.6 0.1 0.0 0.0 0.0 0.0 6.0 2.2 4.8 1.2 1.3 1.8 15.9 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.2 0.0 3.6 6.5 32.4 2.5 0.9 1.1 0.3 0.7 2.3 0.0 0.3 SOX2 ENSG00000181449 "SRY-box transcription factor 2" P48431 3 181711925-181714436 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.2;esophagus: 24.5" "Group enriched" "Detected in some" 6 "Basal squamous epithelial cells: 362.0;Muller glia cells: 383.5;Squamous epithelial cells: 229.1" "Cancer enhanced" "Detected in many" "glioma: 136.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 277.0;HAP1: 118.6;NTERA-2: 226.2;U-251 MG: 54.0" "Low region specificity" "Detected in all" "HPA045725, HPA062851, HPA071379, CAB079745" Enhanced Supported Enhanced Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "CAB079745: , HPA045725: AB_2679431, HPA062851: , HPA071379: " "unprognostic (1.80e-2)" "unprognostic (3.18e-3)" "unprognostic (5.69e-2)" "unprognostic (6.96e-2)" "unprognostic (2.74e-3)" "unprognostic (1.60e-1)" "unprognostic (1.79e-2)" "unprognostic (4.48e-3)" "unprognostic (1.71e-1)" "unprognostic (4.38e-3)" "unprognostic (1.83e-1)" "unprognostic (7.68e-2)" "unprognostic (3.81e-9)" "unprognostic (1.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (1.12e-2)" 0.3 0.9 58.0 0.5 58.5 0.0 0.2 47.1 56.6 2.1 8.6 5.5 0.4 0.1 0.2 24.5 3.1 0.2 0.5 46.5 59.0 0.0 0.1 1.8 0.0 50.5 58.9 0.3 0.1 0.0 13.6 0.0 45.2 2.5 0.4 15.0 18.4 0.3 0.1 0.6 1.4 0.2 59.8 0.0 7.9 1.9 59.2 0.4 0.1 0.1 5.3 1.3 4.8 62.2 0.1 9.0 277.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.3 0.0 0.1 0.0 0.2 0.7 118.6 3.2 0.0 0.1 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 226.2 12.4 0.5 0.0 0.6 0.0 31.0 0.4 0.5 1.2 0.0 0.0 0.1 45.7 1.7 0.1 0.0 0.0 4.2 0.0 54.0 0.0 0.0 0.0 0.2 0.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.0 58.5 47.1 56.6 46.5 59.0 50.5 58.9 45.2 59.8 59.2 62.2 0.2 0.0 6.0 0.0 0.0 0.3 35.5 28.5 362.0 4.9 0.2 0.4 0.5 0.0 48.4 3.7 0.0 0.2 0.0 1.1 0.0 0.0 0.9 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.1 1.6 19.4 0.0 1.3 0.2 0.7 0.1 0.1 0.0 0.0 0.5 38.7 0.0 0.4 0.4 0.6 0.8 3.6 0.0 0.0 383.5 0.0 0.0 0.0 0.0 0.0 0.0 6.1 5.8 0.0 0.1 52.8 13.1 0.0 0.2 1.6 3.9 0.4 229.1 0.4 0.3 0.6 0.2 0.0 7.5 SOX3 PHP ENSG00000134595 "SRY-box transcription factor 3" P41225 X 140502985-140505069 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;fallopian tube: 9.2;testis: 2.3" "Group enriched" "Detected in some" 4 "Astrocytes: 2.9;Muller glia cells: 7.3;Oligodendrocyte precursor cells: 2.0;Skeletal myocytes: 3.1;Spermatogonia: 1.9" "Cancer enhanced" "Detected in some" "glioma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.5;HEK 293: 8.1;NTERA-2: 17.9;SuSa: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054720, HPA075003" Enhanced Nucleoplasm NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA054720: AB_2682584, HPA075003: AB_2686727" "unprognostic (6.04e-2)" "unprognostic (3.75e-1)" "unprognostic (8.62e-3)" "unprognostic (8.03e-2)" "unprognostic (1.57e-1)" "unprognostic (5.27e-3)" 0.0 0.1 1.0 0.0 1.2 0.0 0.0 0.8 1.0 0.2 0.4 0.0 0.0 0.1 0.0 0.0 9.2 0.0 0.0 0.7 4.9 0.0 0.0 0.0 0.0 1.2 1.2 0.0 0.0 0.0 1.8 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 2.3 3.7 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 17.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.2 0.8 1.0 0.7 4.9 1.2 1.2 0.9 1.1 3.7 1.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 7.3 0.0 2.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.1 0.1 0.2 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 SOX4 ENSG00000124766 "SRY-box transcription factor 4" Q06945 6 21593751-21598619 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 73.4" "Cell type enhanced" "Detected in many" "Ductal cells: 1128.5;Granulosa cells: 1047.5;Ionocytes: 1320.3;Pancreatic endocrine cells: 1288.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 45.7" "Group enriched" "Detected in all" 5 "dendritic cells: 45.7;granulocytes: 33.3;monocytes: 22.0" "Cell line enhanced" "Detected in many" "AN3-CA: 254.1;MOLT-4: 229.9" "Region enhanced" "Detected in all" "olfactory bulb: 54.2" HPA029901 Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Mitochondria "HPA029901: AB_10601592" "unprognostic (4.01e-2)" "unprognostic (3.06e-1)" "unprognostic (9.28e-2)" "unprognostic (5.18e-2)" "unprognostic (5.00e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (2.57e-5)" "unprognostic (1.78e-1)" "unprognostic (8.01e-3)" "unprognostic (1.98e-2)" "unprognostic (3.88e-3)" "unprognostic (1.18e-1)" "unprognostic (8.73e-3)" "unprognostic (3.66e-2)" "unprognostic (3.31e-1)" "unprognostic (2.01e-1)" "unprognostic (9.27e-2)" 11.8 4.3 4.7 9.2 5.0 24.0 17.9 8.8 6.7 21.5 2.8 11.9 12.5 57.8 15.0 5.4 13.5 20.4 6.4 4.2 6.5 16.8 6.4 19.3 5.8 3.5 5.0 51.7 10.2 3.6 4.1 6.1 4.1 14.5 14.4 6.4 17.5 6.8 3.5 8.8 11.6 17.4 4.0 5.4 17.5 9.9 7.1 73.4 8.6 6.1 7.4 21.1 7.7 4.2 8.5 24.4 60.5 254.1 22.0 5.5 98.7 3.8 7.8 4.6 4.1 16.7 16.5 2.9 100.2 6.2 3.5 25.1 32.0 17.9 3.3 36.6 66.8 2.7 11.5 11.2 3.5 9.0 2.1 9.6 18.1 2.1 7.3 64.1 72.3 138.8 0.6 0.2 5.2 20.6 229.9 21.6 45.3 12.7 23.1 99.7 5.3 0.4 44.1 78.3 78.9 141.2 35.9 41.1 14.0 74.9 20.1 30.9 55.7 7.1 23.1 1.7 18.6 1.5 0.1 71.8 2.4 30.6 28.5 33.3 19.3 2.1 0.5 11.7 0.1 7.0 0.3 0.3 8.7 6.6 2.2 1.6 0.8 7.4 22.0 45.7 2.1 4.7 4.7 5.0 8.8 6.7 4.2 6.5 3.5 5.0 4.1 4.0 7.1 4.2 235.0 198.7 50.4 0.7 36.2 112.5 129.2 660.7 676.7 99.7 586.1 676.5 297.4 423.2 457.3 154.5 12.5 74.8 104.4 247.6 66.5 1128.5 6.1 669.0 624.2 264.5 340.8 114.3 3.2 604.4 409.4 247.3 313.0 650.9 60.6 1047.5 119.2 6.8 35.5 48.8 4.6 263.0 1320.3 78.0 266.7 12.2 12.2 94.0 243.7 3.7 91.4 189.1 17.5 70.4 1.0 1288.2 153.8 11.3 40.9 151.1 76.7 132.5 162.1 31.6 6.6 234.2 439.9 4.9 236.8 400.7 93.1 30.2 36.6 69.6 299.4 272.5 SOX9 "CMD1, CMPD1, SRA1" ENSG00000125398 "SRY-box transcription factor 9" P48436 17 72121020-72126416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.7;salivary gland: 80.1" "Cell type enhanced" "Detected in many" "Astrocytes: 160.0;Basal squamous epithelial cells: 166.8;Breast glandular cells: 141.0;Cholangiocytes: 190.1;Gastric mucus-secreting cells: 144.8;Muller glia cells: 141.3;Squamous epithelial cells: 273.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 78.1;Hep G2: 97.0;OE19: 74.3;U-251 MG: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001758, CAB022456, CAB068240" Enhanced Enhanced Nucleoplasm NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB022456: , CAB068240: AB_2665670, HPA001758: AB_1080067" "unprognostic (6.92e-2)" "unprognostic (1.73e-2)" "unprognostic (4.47e-3)" "unprognostic (4.43e-2)" "unprognostic (2.55e-2)" "unprognostic (7.96e-3)" "unprognostic (4.32e-3)" "prognostic unfavorable (2.07e-4)" "unprognostic (4.87e-2)" "unprognostic (3.31e-1)" "unprognostic (8.92e-3)" "unprognostic (1.21e-1)" "unprognostic (3.26e-3)" "unprognostic (2.77e-3)" "unprognostic (1.15e-1)" "unprognostic (8.88e-2)" "unprognostic (1.21e-2)" 3.1 2.2 54.7 4.4 50.4 0.1 28.0 42.3 58.5 7.4 46.8 17.1 19.7 2.9 0.9 13.7 7.5 13.0 15.8 50.6 49.3 12.7 3.5 3.1 1.1 73.7 72.2 0.3 38.4 0.1 10.3 0.3 48.8 24.8 17.8 15.0 80.1 10.9 2.7 23.3 15.1 1.2 56.9 0.2 40.5 30.7 51.4 0.5 20.2 1.2 4.4 1.9 6.4 49.0 31.1 19.2 38.9 78.1 3.9 1.1 0.1 4.8 4.2 8.2 4.4 27.0 40.8 0.0 2.9 1.1 43.8 31.3 0.0 18.6 7.5 0.0 2.5 0.0 4.2 97.0 0.3 0.0 0.1 0.7 1.6 9.5 9.0 47.0 0.0 0.0 0.0 0.1 11.7 0.4 0.0 0.1 1.5 74.3 29.1 0.0 31.4 0.4 35.2 2.0 1.9 1.9 4.0 4.7 0.1 21.0 16.7 0.2 0.0 15.8 42.0 8.5 66.5 0.0 0.0 0.1 11.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 50.4 42.3 58.5 50.6 49.3 73.7 72.2 48.8 56.9 51.4 49.0 1.1 12.8 5.6 160.0 1.9 55.4 88.2 28.9 166.8 3.0 141.0 108.2 13.6 190.1 21.1 36.8 0.0 0.3 2.8 52.1 7.9 55.3 5.1 18.4 0.9 3.2 59.7 0.0 3.1 46.7 0.0 26.0 144.8 21.7 4.5 1.9 0.0 3.4 0.2 0.0 1.5 99.0 24.4 0.0 3.4 14.5 4.4 2.3 12.4 9.4 1.0 141.3 0.0 4.5 11.1 40.8 39.1 0.4 2.8 81.1 17.7 61.0 36.4 6.8 6.6 59.9 14.5 10.2 3.1 273.5 17.8 0.1 2.8 0.1 103.8 77.2 SP7 "osterix, OSX" ENSG00000170374 "Sp7 transcription factor" Q8TDD2 12 53326575-53345315 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Cone photoreceptor cells: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "olfactory bulb: 28.1" "Low region specificity" "Detected in many" HPA063202 Enhanced NA NA "Cluster 9: Photoreceptor cells - Phototransduction" "HPA063202: AB_2684961" "unprognostic (6.02e-1)" "unprognostic (6.28e-3)" "unprognostic (6.37e-2)" "unprognostic (2.49e-2)" "unprognostic (7.75e-2)" "unprognostic (3.02e-1)" "unprognostic (1.49e-1)" "unprognostic (2.11e-1)" "unprognostic (1.04e-2)" "unprognostic (6.02e-1)" "unprognostic (3.93e-7)" "unprognostic (6.04e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "unprognostic (1.95e-1)" 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.5 0.2 0.4 0.3 0.2 0.3 0.1 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2184.6" "Cell type enhanced" "Detected in many" "Adipocytes: 737.1;Endometrial stromal cells: 1209.0;Endothelial cells: 781.9;Fibroblasts: 1032.1;Peritubular cells: 1111.1;Sertoli cells: 2353.5;Smooth muscle cells: 1527.3;Theca cells: 987.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.3" "Group enriched" "Detected in many" 7 "granulocytes: 24.3;monocytes: 8.7" "Cell line enhanced" "Detected in many" "ASC diff: 4911.5;BJ: 4101.8;fHDF/TERT166: 6492.5;WM-115: 4789.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" NA NA 8300000 130000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" 1661.2 406.4 578.0 436.4 922.0 32.4 528.6 733.1 339.2 837.2 297.8 355.6 110.5 538.9 112.7 307.7 271.4 1526.8 563.5 362.9 1554.2 176.1 158.5 498.0 232.1 1370.4 1251.5 348.2 119.2 273.1 111.4 2184.6 1224.8 227.1 185.2 36.4 113.1 378.0 258.2 286.1 157.4 1251.5 995.9 260.8 143.3 406.7 1135.4 70.9 294.1 473.5 131.6 829.5 249.0 1088.4 5.9 5.0 1196.5 57.5 4911.5 1596.0 112.6 4101.8 1336.6 1649.3 1693.8 5.5 4.2 2.0 953.7 6492.5 272.0 56.7 153.4 316.2 555.0 4.8 57.1 56.7 0.4 116.8 1441.6 2.9 5.4 2567.2 436.9 1233.8 170.8 1903.1 2315.1 13.5 53.7 44.6 944.1 0.4 4.7 35.5 556.2 0.4 4.4 2.9 1192.9 4.3 0.5 0.5 45.5 88.4 2.8 1.4 534.9 1922.1 4.7 138.2 2759.9 771.0 1195.2 350.2 1304.4 3.7 6.0 7.6 648.4 3.7 4789.0 10.4 8.7 2.7 1.0 0.3 0.0 0.1 0.0 0.1 2.3 0.2 0.3 0.0 24.3 0.0 0.1 1.9 0.0 123.9 578.0 922.0 733.1 339.2 362.9 1554.2 1370.4 1251.5 1224.8 995.9 1135.4 1088.4 737.1 83.3 27.5 7.2 6.8 164.8 25.7 23.8 28.5 85.7 11.2 100.5 43.6 5.7 18.8 16.5 2.1 115.4 2.8 0.1 0.0 4.6 14.2 41.6 1209.0 781.9 0.0 15.1 4.3 0.4 354.3 1032.1 9.7 31.5 12.0 146.5 668.6 9.9 108.2 1.7 2.9 0.0 0.0 50.0 175.7 46.8 319.3 92.0 234.7 38.4 10.7 13.6 3.1 21.6 37.3 5.5 0.0 1111.1 4.1 7.7 0.0 42.0 7.8 72.7 2353.5 510.4 1527.3 14.2 10.9 4.8 108.3 147.4 21.1 987.4 0.0 5.3 SPECC1L "CYTSA, KIAA0376" ENSG00000100014 "Sperm antigen with calponin homology and coiled-coil domains 1 like" Q69YQ0 22 24270817-24417739 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA070614 Uncertain Supported "Actin filaments" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Actin filaments" "HPA070614: AB_2686287" "unprognostic (3.54e-1)" "unprognostic (4.93e-3)" "unprognostic (1.62e-1)" "unprognostic (5.88e-2)" "unprognostic (3.74e-2)" "unprognostic (1.28e-1)" "unprognostic (2.54e-1)" "unprognostic (7.82e-3)" "unprognostic (4.98e-2)" "unprognostic (1.72e-3)" "prognostic favorable (7.92e-4)" "unprognostic (3.15e-3)" "unprognostic (6.20e-3)" "unprognostic (1.40e-1)" "unprognostic (3.71e-1)" "unprognostic (5.79e-3)" "unprognostic (1.41e-1)" 13.0 13.1 12.3 12.4 12.8 13.3 13.8 34.0 13.5 16.6 17.7 15.8 7.8 15.9 9.7 17.5 15.5 12.5 18.6 10.8 15.7 14.6 14.4 17.2 12.5 18.1 16.2 22.0 13.3 17.3 14.6 10.1 18.9 20.1 16.9 10.7 16.2 15.1 12.7 9.2 11.6 19.0 15.8 11.1 11.5 31.9 16.6 14.5 24.0 13.1 13.8 14.9 13.0 13.7 31.1 22.8 42.9 23.7 40.1 39.2 14.5 43.1 34.1 36.8 36.4 25.5 8.4 44.9 10.3 39.5 29.0 27.0 39.2 24.2 43.4 26.1 21.1 28.5 12.9 23.4 26.7 51.2 27.0 33.1 19.2 32.8 34.2 28.8 44.0 18.9 24.5 19.0 39.3 17.3 26.6 18.5 20.7 22.5 17.1 24.0 43.3 16.1 18.4 23.3 37.2 38.3 36.5 27.5 23.8 37.1 18.3 14.4 46.3 77.2 43.7 19.3 29.3 22.7 23.4 20.0 22.6 19.0 29.2 3.9 2.4 4.8 3.3 3.5 2.5 2.8 2.2 1.6 2.3 3.1 2.7 2.9 3.2 1.3 1.6 3.7 1.6 1.9 12.3 12.8 34.0 13.5 10.8 15.7 18.1 16.2 18.9 15.8 16.6 13.7 11.6 16.0 21.3 0.0 10.4 3.6 2.7 5.0 10.2 8.4 13.8 9.4 13.7 14.3 9.1 12.9 10.4 7.3 7.9 32.8 1.9 6.7 26.9 8.3 14.9 12.0 14.4 7.6 0.0 7.4 3.2 11.4 8.2 9.8 16.5 13.4 15.7 11.4 7.3 10.1 0.0 12.2 14.2 7.3 2.2 93.7 16.1 6.9 14.2 0.0 14.8 6.4 9.2 0.0 0.0 9.0 15.0 13.5 10.7 5.7 8.9 6.1 11.9 8.5 13.1 11.3 12.5 24.1 28.5 9.8 3.1 5.9 9.3 7.6 8.0 3.8 SPINK5 "DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI" ENSG00000133710 "Serine peptidase inhibitor Kazal type 5" Q9NQ38 5 148025683-148137382 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 338.5;esophagus: 1015.0;skin 1: 318.2;vagina: 582.6" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 1622.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 45.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 14.7;HeLa: 22.7;Karpas-707: 19.3;SuSa: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009067, HPA011351, CAB015347" Enhanced Enhanced Vesicles "Secreted in other tissues" NA NA 43000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB015347: AB_2196138, HPA009067: AB_1080084, HPA011351: AB_1857447" "unprognostic (9.66e-3)" "unprognostic (1.42e-2)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.42e-3)" "unprognostic (2.45e-2)" "unprognostic (6.85e-2)" "unprognostic (1.16e-1)" "unprognostic (2.28e-2)" "unprognostic (4.92e-3)" "unprognostic (4.56e-1)" "unprognostic (2.44e-1)" "unprognostic (7.91e-2)" "unprognostic (2.82e-1)" "unprognostic (6.87e-2)" "unprognostic (2.59e-1)" 1.1 0.3 0.0 0.5 0.1 0.0 17.5 0.0 0.2 338.5 0.0 4.8 0.3 0.6 0.3 1015.0 0.4 1.8 1.7 0.1 0.0 0.8 0.4 2.0 0.1 0.1 0.1 0.3 0.8 1.0 2.0 2.4 0.2 1.3 10.6 0.0 145.0 0.5 1.8 318.2 0.6 0.4 0.0 0.3 5.0 1.6 0.1 9.1 2.2 1.1 292.9 0.7 582.6 0.3 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.2 1.8 0.0 0.0 14.7 0.0 1.3 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.3 0.0 0.0 3.9 0.0 0.0 0.0 0.2 0.0 0.9 19.3 0.0 2.1 0.0 0.0 2.6 2.0 0.3 0.0 0.0 0.0 0.0 5.7 2.8 0.0 0.6 0.0 0.0 6.6 4.6 0.0 0.0 0.0 0.1 0.0 0.0 5.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.3 5.7 9.6 45.4 0.3 0.2 53.7 1.5 331.1 102.4 0.0 4.2 3.4 1.2 34.3 115.6 0.0 0.0 1.9 0.0 177.9 0.0 0.2 11.0 2.5 0.7 12.9 4.2 0.0 0.7 1.3 2.1 2.6 17.9 4.8 1.3 0.0 7.9 0.2 0.1 0.0 0.8 33.8 16.2 0.8 2.1 3.8 0.6 0.7 3.6 2.8 0.0 0.0 0.0 2.0 1.2 7.6 60.3 0.0 3.7 0.7 0.0 0.0 9.4 0.0 0.0 0.2 2.4 1.3 4.6 1622.6 64.4 1.5 1.1 1.0 97.9 2.7 SPRED1 "FLJ33903, PPP1R147" ENSG00000166068 "Sprouty related EVH1 domain containing 1" Q7Z699 15 38252836-38357249 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 173.7;Excitatory neurons: 163.4;Microglial cells: 199.5;Oligodendrocyte precursor cells: 277.9;Oligodendrocytes: 146.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 4 "monocytes: 1.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042193, HPA061805" Approved Supported Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA042193: AB_10794079, HPA061805: AB_2684617" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (2.46e-1)" "prognostic favorable (7.08e-4)" "unprognostic (1.20e-1)" "unprognostic (2.38e-1)" "unprognostic (1.21e-3)" "unprognostic (5.71e-2)" "unprognostic (3.84e-2)" "unprognostic (2.81e-3)" "unprognostic (9.27e-3)" "unprognostic (3.33e-1)" "prognostic unfavorable (7.37e-5)" "prognostic unfavorable (8.29e-5)" "unprognostic (6.04e-2)" "unprognostic (5.77e-2)" "unprognostic (1.01e-1)" 12.7 8.2 16.0 8.8 20.3 0.7 10.9 14.7 20.6 11.5 7.1 11.4 8.2 10.9 5.7 6.1 6.9 12.8 7.3 16.5 16.3 9.1 5.6 17.4 7.1 18.9 19.6 7.9 4.5 6.8 4.0 14.0 16.2 7.2 10.9 7.5 5.6 8.6 2.6 6.1 8.4 9.5 15.6 9.0 10.3 8.2 17.9 4.4 31.1 8.0 4.9 13.2 6.8 18.3 11.0 8.2 59.0 11.3 21.4 39.0 4.8 25.1 24.7 13.1 16.2 7.6 8.7 0.1 9.0 21.7 9.5 8.6 6.2 17.3 26.2 1.5 2.0 13.0 5.2 7.3 26.3 7.1 34.6 25.5 8.5 25.5 23.4 33.6 10.7 6.5 11.7 12.1 32.2 2.9 2.6 5.2 12.0 37.6 22.0 0.0 13.3 7.3 21.2 16.9 2.9 13.0 7.2 3.5 26.7 9.3 2.8 1.7 18.2 32.0 15.7 19.7 15.4 10.1 7.1 16.7 22.5 2.8 52.1 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 16.0 20.3 14.7 20.6 16.5 16.3 18.9 19.6 16.2 15.6 17.9 18.3 26.4 99.3 26.9 173.7 2.5 28.3 24.6 9.4 45.5 12.6 17.2 20.8 7.2 28.6 12.6 1.8 6.2 1.3 1.5 15.7 1.9 9.5 40.3 12.0 29.4 28.2 6.7 4.6 163.4 4.9 0.9 33.0 17.3 14.8 41.8 5.4 26.7 4.1 57.8 5.0 100.0 21.2 6.1 48.2 24.6 9.6 21.8 38.7 28.4 199.5 7.3 25.4 0.0 277.9 146.9 15.1 7.8 30.5 1.6 12.7 6.6 12.8 11.4 5.2 6.6 44.4 44.1 8.0 5.0 18.1 9.7 1.4 2.4 21.4 15.3 14.7 SRCAP "DOMO1, EAF1, KIAA0309, SWR1" ENSG00000080603 "Snf2 related CREBBP activator protein" Q6ZRS2 16 30698209-30741409 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 186.4;Club cells: 145.6;Ionocytes: 179.0;Respiratory ciliated cells: 118.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" HPA028929 Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA028929: AB_10601265" "unprognostic (1.26e-1)" "unprognostic (1.35e-1)" "unprognostic (5.07e-1)" "unprognostic (6.57e-2)" "unprognostic (1.78e-1)" "unprognostic (6.95e-2)" "unprognostic (8.59e-2)" "unprognostic (2.34e-2)" "unprognostic (3.77e-1)" "unprognostic (6.45e-2)" "unprognostic (4.36e-2)" "unprognostic (8.57e-2)" "unprognostic (1.16e-2)" "unprognostic (2.09e-1)" "unprognostic (4.11e-2)" "unprognostic (7.71e-2)" "unprognostic (1.07e-1)" 15.4 11.9 3.6 18.9 4.8 30.1 10.1 7.1 4.2 12.8 1.7 13.2 15.7 15.5 6.4 13.5 14.2 10.9 12.1 2.9 3.4 9.6 7.1 11.6 15.3 5.9 4.3 16.9 19.4 20.2 9.5 12.6 3.5 12.6 11.2 12.5 18.0 13.1 24.5 16.2 16.1 15.0 0.8 18.7 16.0 20.6 7.7 20.2 14.0 19.4 13.6 11.3 9.9 6.8 29.5 60.1 36.9 35.9 28.3 19.5 37.7 24.0 21.1 26.2 20.7 27.8 21.9 65.9 29.7 30.5 16.9 27.8 37.7 27.5 21.9 42.2 88.1 42.5 56.2 24.3 11.4 49.8 48.0 20.8 13.2 40.3 29.0 12.8 27.8 21.7 65.4 36.5 19.7 34.5 42.2 17.4 37.6 10.8 27.7 57.7 28.7 36.4 7.5 34.2 34.5 36.5 26.6 31.0 8.4 12.2 35.4 26.0 44.1 37.0 26.5 21.0 31.6 39.8 36.7 45.9 29.7 23.2 28.9 0.3 0.7 2.9 0.8 1.2 0.6 0.7 0.4 0.9 0.5 1.0 0.5 0.4 2.2 0.6 0.3 0.9 0.9 0.7 3.6 4.8 7.1 4.2 2.9 3.4 5.9 4.3 3.5 0.8 7.7 6.8 3.0 3.2 3.7 8.8 9.8 24.6 1.9 186.4 13.1 7.5 3.3 1.8 2.4 4.3 145.6 1.8 8.4 2.3 5.3 54.3 0.0 1.4 1.2 4.6 3.0 3.4 11.3 7.6 8.6 3.1 1.4 4.2 19.9 4.7 2.5 3.0 2.2 3.0 2.3 8.4 8.6 17.7 179.0 1.9 14.3 0.9 2.8 3.4 10.6 8.4 3.0 1.7 6.2 4.5 10.6 1.9 39.1 1.2 11.1 3.1 3.1 0.6 118.3 5.8 0.0 5.0 14.3 5.6 6.0 7.8 58.2 2.5 8.9 2.0 25.6 3.1 SREBF1 "bHLHd1, SREBP-1c, SREBP1, SREBP1a" ENSG00000072310 "Sterol regulatory element binding transcription factor 1" P36956 17 17810399-17837011 "Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 219.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "RPMI-8226: 202.5;SK-BR-3: 178.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005406, HPA043343, HPA043878" Uncertain Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Golgi apparatus, Cytosol" "CAB005406: AB_2194226, HPA043343: AB_2678439, HPA043878: AB_2678710" "unprognostic (9.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-2)" "prognostic favorable (2.66e-4)" "unprognostic (4.50e-2)" "unprognostic (1.05e-2)" "unprognostic (9.85e-2)" "unprognostic (1.15e-1)" "unprognostic (3.14e-2)" "unprognostic (9.02e-3)" "prognostic favorable (9.05e-4)" "unprognostic (3.12e-1)" "unprognostic (9.02e-3)" "unprognostic (1.11e-2)" "unprognostic (1.20e-1)" "unprognostic (7.65e-2)" "unprognostic (2.36e-3)" 42.2 219.2 26.8 7.9 41.5 20.1 46.5 20.4 37.2 51.5 9.4 37.7 28.7 23.4 8.9 68.7 42.7 14.0 27.4 20.0 25.9 24.7 128.5 26.4 9.1 30.1 29.7 41.4 17.0 8.4 37.0 7.8 24.2 37.2 6.7 3.9 89.5 16.7 34.5 47.8 34.0 5.6 23.4 17.2 25.2 35.4 35.8 14.4 27.0 2.9 6.3 32.5 48.8 41.7 54.1 122.5 12.0 85.2 24.9 55.8 23.5 18.5 60.0 16.4 39.2 23.3 104.2 33.5 17.2 14.8 14.5 144.0 16.7 47.2 4.0 21.1 7.2 16.8 86.4 19.1 36.1 2.5 29.6 42.0 19.6 21.8 12.5 12.2 17.6 64.9 36.8 105.8 2.5 118.7 46.9 26.1 17.8 38.3 23.1 32.6 10.8 202.5 9.0 23.1 16.3 70.5 24.4 178.7 48.0 8.9 62.0 32.6 21.5 8.2 40.5 19.5 12.5 32.2 3.1 15.5 48.9 24.6 45.2 0.0 0.3 0.1 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.4 0.6 1.3 0.1 0.1 0.1 0.0 0.2 26.8 41.5 20.4 37.2 20.0 25.9 30.1 29.7 24.2 23.4 35.8 41.7 6.1 6.4 26.0 66.9 11.9 9.3 12.0 29.2 14.8 24.5 58.0 30.6 9.4 18.6 29.7 20.2 29.2 4.5 11.4 44.5 1.9 16.5 2.7 30.9 37.2 10.5 29.9 24.8 12.8 23.5 15.7 24.7 31.1 31.9 14.7 13.2 12.8 72.2 12.1 58.9 11.3 30.8 24.4 14.0 13.3 4.9 29.8 15.1 8.8 15.0 11.0 51.7 1.0 10.6 56.7 16.7 20.8 10.9 8.4 19.0 33.2 6.6 32.1 31.6 13.1 15.6 12.9 11.4 4.9 40.2 18.3 19.8 13.4 27.5 41.1 25.2 ST14 "HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "ST14 transmembrane serine protease matriptase" Q9Y5Y6 11 130159782-130210362 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 489.4;Paneth cells: 327.2;Proximal enterocytes: 251.9;Undifferentiated cells: 216.9;Urothelial cells: 286.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 10.0" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 25.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 25.0" "Cell line enhanced" "Detected in many" "CACO-2: 224.2;CAPAN-2: 443.0;HaCaT: 311.4;OE19: 240.4;RPMI-8226: 301.2;SK-BR-3: 203.1;T-47d: 308.3;U-698: 218.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA047014, HPA056258" Enhanced Approved Nucleoplasm,Vesicles NA NA 1100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA047014: AB_2679902, HPA056258: " "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favorable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" 4.3 3.9 0.8 26.7 1.2 4.3 17.7 1.8 2.9 18.6 1.2 124.7 130.7 5.7 21.8 104.5 37.1 32.6 0.9 0.9 1.1 43.2 6.3 18.5 11.9 1.8 1.7 0.6 59.2 36.5 19.1 15.1 3.1 23.1 60.1 0.0 58.7 23.6 0.3 50.2 144.8 5.4 1.1 9.1 64.9 1.0 10.0 10.5 28.6 0.0 20.9 34.8 42.5 2.7 167.2 0.2 0.0 0.6 0.0 0.0 86.4 0.0 0.0 0.0 0.0 224.2 443.0 163.6 16.7 0.0 0.1 311.4 0.0 99.3 0.0 0.1 0.2 0.1 0.1 0.9 0.0 22.0 0.8 0.0 49.3 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 128.5 0.3 1.1 1.7 240.4 0.9 0.2 0.0 301.2 28.8 134.2 17.8 0.4 1.5 203.1 0.4 1.6 308.3 32.0 0.1 0.4 2.7 0.7 0.7 0.2 0.3 218.5 0.3 50.4 0.5 0.0 3.6 3.4 0.0 2.2 0.1 5.0 0.0 0.0 6.2 3.6 0.0 0.0 0.5 0.0 0.3 25.0 0.0 1.2 0.8 1.2 1.8 2.9 0.9 1.1 1.8 1.7 3.1 1.1 10.0 2.7 0.2 32.1 28.6 0.0 18.2 40.9 51.5 45.2 26.2 0.0 36.5 21.5 1.2 77.2 61.6 62.5 0.0 45.6 26.1 489.4 3.9 115.8 37.8 43.9 5.7 1.7 123.4 0.8 1.0 91.8 14.6 3.2 112.1 79.6 11.4 0.2 0.4 2.1 58.1 0.0 0.4 201.0 148.5 22.7 13.2 13.9 1.8 28.0 7.2 0.0 13.6 0.0 1.0 0.0 0.1 153.4 327.2 0.7 5.9 108.7 251.9 10.0 76.4 0.0 6.6 0.0 4.9 0.2 0.3 61.3 43.9 39.7 2.9 0.0 216.9 286.8 STAG2 "SA-2, SA2, SCC3B" ENSG00000101972 "Stromal antigen 2" Q8N3U4 X 123960212-124422664 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Cancer-related genes, Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002857 Supported Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA002857: AB_1079861" "unprognostic (1.62e-1)" "unprognostic (1.01e-2)" "unprognostic (6.75e-2)" "unprognostic (2.16e-2)" "unprognostic (1.37e-2)" "unprognostic (2.70e-2)" "unprognostic (3.77e-2)" "unprognostic (9.67e-3)" "unprognostic (4.68e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-1)" "unprognostic (3.38e-1)" "unprognostic (1.59e-3)" "unprognostic (2.81e-1)" "unprognostic (2.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.97e-1)" 27.9 22.9 20.7 34.2 26.3 72.8 41.5 32.6 24.1 33.3 30.4 28.8 23.8 35.7 28.3 26.8 30.1 25.2 21.5 18.0 22.6 33.7 28.5 28.6 45.0 26.2 21.9 46.0 31.7 51.9 12.0 35.8 27.8 29.8 28.2 45.5 26.5 29.6 23.3 26.1 26.5 25.8 24.2 37.4 28.5 8.0 21.2 81.4 49.3 36.0 44.3 28.4 17.6 39.6 62.6 56.9 84.5 53.0 34.9 52.3 54.4 58.0 61.8 58.5 73.2 53.8 65.1 115.0 79.6 52.3 65.5 55.6 173.6 48.8 82.5 81.9 74.7 106.6 110.8 35.7 35.6 140.7 80.0 42.2 46.4 69.5 111.4 50.2 49.7 114.2 105.4 118.9 43.1 67.8 180.6 62.9 44.5 55.8 84.4 125.9 112.0 96.1 44.9 117.3 75.7 60.6 131.2 47.7 66.9 59.2 28.9 62.2 61.5 0.3 31.1 69.4 66.6 50.9 82.2 141.6 36.8 84.3 60.3 28.2 15.2 28.0 15.0 18.9 17.8 15.0 15.6 14.6 19.1 19.0 21.3 17.5 44.5 18.8 23.1 16.5 13.5 10.0 20.7 26.3 32.6 24.1 18.0 22.6 26.2 21.9 27.8 24.2 21.2 39.6 71.1 64.1 56.6 42.4 80.9 56.2 61.5 31.5 72.3 51.0 58.0 48.4 44.9 37.1 50.6 44.1 60.5 32.2 113.4 42.9 21.5 42.3 1.1 65.1 70.4 62.3 58.1 77.0 41.8 38.2 32.7 64.5 39.8 79.3 58.1 53.6 59.3 42.2 36.0 45.4 51.9 35.0 28.5 71.4 65.0 4.2 65.9 89.9 33.8 70.3 91.4 61.2 97.9 69.4 114.0 54.9 29.3 69.2 73.8 81.4 28.0 35.7 51.4 62.9 65.7 104.0 60.3 14.8 15.4 51.0 56.1 71.4 87.2 49.5 38.9 83.6 STAMBP AMSH ENSG00000124356 "STAM binding protein" O95630 2 73828916-73873659 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 12 "LHCN-M2: 1108.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035800, HPA035801" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA035800: AB_10670591, HPA035801: AB_2732470" "unprognostic (1.86e-2)" "unprognostic (1.14e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (4.70e-5)" "unprognostic (6.13e-2)" "unprognostic (2.08e-3)" "unprognostic (3.73e-2)" "unprognostic (1.71e-1)" "unprognostic (6.58e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (1.01e-1)" "unprognostic (2.29e-1)" "unprognostic (7.72e-2)" "unprognostic (2.63e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" 15.6 11.6 21.7 14.6 30.6 13.3 20.2 29.7 23.8 19.3 19.3 21.5 20.7 20.6 15.5 25.4 18.3 16.9 22.3 20.6 24.5 21.9 19.0 15.7 19.3 31.3 28.0 17.7 12.2 24.3 9.3 17.3 30.4 22.1 23.2 14.6 21.5 15.6 37.4 16.7 20.4 21.3 27.9 14.9 18.2 15.8 27.1 23.2 22.6 42.8 21.6 16.8 16.0 38.6 39.0 44.0 34.0 31.6 31.1 37.2 39.1 23.3 31.7 42.1 40.3 73.7 35.9 32.2 35.8 19.8 55.7 30.0 36.6 81.7 47.6 56.6 41.3 43.3 29.1 58.1 43.4 35.8 50.0 30.1 57.6 49.6 70.7 53.5 25.1 43.7 47.9 47.8 1108.9 46.8 55.9 32.4 54.9 55.1 22.7 38.6 89.4 46.1 45.2 43.0 62.0 45.8 28.4 34.6 49.1 36.4 32.3 21.4 22.0 37.5 44.5 22.9 41.9 44.8 46.9 24.9 46.4 38.1 44.7 30.7 18.9 34.2 15.9 21.4 17.2 21.5 18.3 15.6 19.9 19.3 18.9 14.4 27.6 22.3 19.9 19.5 25.8 14.9 21.7 30.6 29.7 23.8 20.6 24.5 31.3 28.0 30.4 27.9 27.1 38.6 22.1 19.2 17.7 22.9 21.5 16.3 28.9 61.7 31.3 22.3 28.8 27.7 41.1 28.6 34.4 25.8 12.5 43.0 27.4 48.7 49.0 37.9 80.8 35.6 37.3 21.4 10.3 34.9 18.5 36.3 32.5 26.0 18.8 45.8 52.6 21.2 17.5 41.1 33.0 26.9 22.1 36.4 40.7 27.7 16.2 125.0 32.6 25.2 7.2 16.9 34.1 24.9 25.7 26.2 67.2 44.5 41.8 34.6 21.5 40.9 57.2 68.8 24.5 21.0 39.5 28.2 27.2 33.1 44.2 44.5 21.6 44.5 21.4 27.5 34.3 27.1 STIL "MCPH7, SIL" ENSG00000123473 "STIL centriolar assembly protein" Q15468 1 47250139-47314147 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.8;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Glandular and luminal cells: 12.4;Spermatocytes: 17.8;Spermatogonia: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046543 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA046543: AB_2679692" "unprognostic (2.07e-1)" "unprognostic (6.29e-2)" "unprognostic (5.54e-3)" "unprognostic (2.67e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-2)" "unprognostic (2.90e-5)" "unprognostic (7.35e-3)" "unprognostic (4.04e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.81e-2)" "unprognostic (3.36e-14)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" 1.0 0.5 0.8 3.0 0.8 10.8 2.9 0.7 1.2 1.1 0.2 4.1 2.9 1.4 1.4 2.5 0.9 1.4 0.6 0.8 0.6 0.7 1.0 0.9 4.9 0.7 0.6 0.8 0.7 0.9 0.4 1.9 0.8 1.3 5.6 1.2 1.7 0.5 0.6 3.1 2.7 1.4 0.4 1.4 1.8 6.6 0.8 9.9 0.9 0.7 5.7 1.1 1.0 1.0 33.7 17.4 24.7 22.1 1.8 3.8 15.7 29.3 14.0 32.0 33.2 18.5 16.1 39.4 13.3 14.4 32.7 21.4 29.4 15.3 33.7 29.6 12.9 44.5 20.9 16.6 0.8 35.7 21.5 1.6 2.1 27.2 17.5 3.8 21.5 29.5 31.7 35.9 24.1 14.3 35.6 10.9 30.0 18.6 14.2 23.0 40.3 19.0 9.0 20.0 22.0 13.2 31.4 22.2 14.6 29.6 14.5 20.6 12.2 29.6 29.9 21.2 40.0 11.9 26.4 38.1 13.8 27.0 28.0 0.3 0.1 0.2 0.2 0.0 0.0 0.4 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.7 0.0 0.3 0.3 0.1 0.8 0.8 0.7 1.2 0.8 0.6 0.7 0.6 0.8 0.4 0.8 1.0 1.6 3.2 0.5 2.0 2.4 0.9 0.6 2.0 1.2 1.1 2.8 3.0 0.5 0.0 2.3 0.0 4.2 2.5 1.6 5.4 0.0 1.6 1.6 7.8 3.2 2.2 1.8 12.8 5.1 0.4 4.4 1.6 3.1 12.4 2.5 8.2 1.4 0.5 2.9 0.0 3.9 6.1 0.0 2.4 1.2 1.1 0.3 2.7 0.0 0.0 3.0 0.8 1.0 2.0 4.8 1.9 1.8 0.7 10.2 1.1 1.4 0.4 7.6 0.6 0.0 1.7 2.0 17.8 14.4 5.3 2.4 0.8 3.3 2.6 5.5 1.4 STRA6 FLJ12541 ENSG00000137868 "Signaling receptor and transporter of retinol STRA6" Q9BX79 15 74179466-74212267 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Receptor "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.5" "Cell type enhanced" "Detected in many" "Club cells: 17.6;Endometrial stromal cells: 43.1;Extravillous trophoblasts: 12.1;Fibroblasts: 16.1;Proximal tubular cells: 10.3;Syncytiotrophoblasts: 26.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 33.7;CAPAN-2: 94.5;SH-SY5Y: 59.2;WM-115: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040839 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA040839: AB_10794881" "unprognostic (1.20e-2)" "unprognostic (4.99e-2)" "unprognostic (3.71e-2)" "unprognostic (3.55e-3)" "unprognostic (1.37e-1)" "unprognostic (2.09e-2)" "unprognostic (4.38e-3)" "unprognostic (1.67e-2)" "unprognostic (9.16e-2)" "unprognostic (1.21e-1)" "unprognostic (5.35e-2)" "unprognostic (3.89e-1)" "unprognostic (7.91e-13)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (1.51e-2)" "unprognostic (1.91e-1)" 0.1 1.0 0.1 0.3 0.0 0.0 0.9 0.0 0.4 24.5 0.4 0.1 0.0 4.3 0.5 1.1 3.6 0.3 0.1 0.1 0.1 4.3 0.0 0.2 0.8 0.1 0.0 0.6 0.1 0.0 5.5 7.6 0.0 5.2 0.0 0.0 0.7 1.4 0.0 0.3 0.2 0.2 0.1 0.1 0.0 3.1 0.3 0.2 0.1 0.1 0.5 1.3 2.4 0.0 0.5 33.7 1.9 0.1 0.0 0.0 6.0 1.0 0.2 0.0 0.0 11.7 94.5 0.0 22.1 0.1 0.7 3.4 1.8 0.0 0.0 0.0 0.2 3.0 1.3 2.5 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.4 6.1 0.6 2.9 0.1 0.0 0.4 0.0 0.0 0.0 2.9 17.4 59.2 0.0 3.6 0.0 3.6 0.2 0.1 0.0 0.2 7.3 0.6 1.6 0.1 0.2 0.0 0.6 0.0 142.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.4 1.0 9.7 0.0 0.0 0.2 0.3 1.0 0.0 17.6 0.0 0.0 4.2 0.0 0.0 1.9 0.3 1.7 2.1 43.1 1.3 0.0 0.0 0.1 0.0 12.1 16.1 0.0 1.8 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 2.0 0.0 0.8 0.8 6.8 0.4 1.8 1.9 0.1 0.0 0.0 0.0 0.0 4.7 0.0 4.1 0.0 0.4 0.0 10.3 6.6 0.0 0.0 1.3 4.7 0.5 0.5 0.0 0.0 26.4 0.3 0.1 0.0 1.3 STRADA "LYK5, NY-BR-96, Stlk, STRAD" ENSG00000266173 "STE20 related adaptor alpha" Q7RTN6 17 63682336-63741986 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 48.0;Excitatory neurons: 49.1;Inhibitory neurons: 47.5;Oligodendrocyte precursor cells: 33.2;Oligodendrocytes: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031637 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA031637: AB_10601718" "unprognostic (1.59e-1)" "unprognostic (2.19e-1)" "unprognostic (5.59e-3)" "unprognostic (5.52e-2)" "unprognostic (8.91e-2)" "unprognostic (7.56e-5)" "unprognostic (6.79e-4)" "unprognostic (3.68e-2)" "unprognostic (1.70e-1)" "unprognostic (2.28e-1)" "prognostic favorable (5.34e-5)" "unprognostic (7.29e-2)" "prognostic unfavorable (6.08e-7)" "unprognostic (1.40e-1)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "prognostic favorable (6.43e-4)" 21.3 28.3 32.2 12.7 32.9 18.3 19.6 31.9 35.8 23.9 30.0 23.0 8.8 20.5 18.2 21.1 23.0 13.4 23.1 32.9 32.6 27.8 23.0 19.0 20.3 34.3 31.8 24.7 17.7 19.1 26.4 13.4 32.6 22.5 11.6 13.9 15.6 14.3 14.6 20.8 19.4 17.2 31.0 32.0 20.5 49.0 32.4 20.1 20.0 10.1 20.4 22.6 20.0 32.8 12.7 37.5 31.9 32.3 30.8 22.8 12.4 23.8 21.6 33.6 29.8 9.9 14.4 19.5 14.4 20.3 16.7 10.5 21.4 23.1 33.0 21.5 20.7 38.4 25.9 23.7 21.8 36.7 26.5 23.9 19.4 38.2 22.1 22.3 37.6 30.0 24.9 20.0 32.2 23.6 43.4 25.0 16.0 10.7 21.2 27.9 50.8 23.8 30.2 24.9 36.0 39.4 16.3 26.3 26.1 32.9 19.7 26.4 30.5 31.7 22.5 25.8 20.0 19.9 22.9 24.3 23.4 21.8 25.7 19.2 9.5 8.8 9.6 6.9 8.8 10.3 8.7 10.7 15.8 7.5 8.5 7.6 10.8 16.8 10.7 13.3 7.3 8.0 32.2 32.9 31.9 35.8 32.9 32.6 34.3 31.8 32.6 31.0 32.4 32.8 6.4 9.6 7.3 48.0 12.5 0.0 0.1 0.5 6.2 2.1 3.6 3.4 0.5 0.0 2.9 9.2 0.0 2.1 9.3 1.2 0.0 7.0 1.1 8.6 9.4 3.7 0.0 3.4 49.1 2.8 0.9 4.7 6.1 7.2 2.5 12.7 0.7 0.1 1.5 1.7 47.5 2.2 2.0 1.3 1.4 2.2 0.6 6.7 0.0 27.2 17.9 1.2 5.2 33.2 71.4 4.8 2.0 1.5 10.2 0.4 1.9 2.0 2.5 3.7 0.0 2.0 4.1 3.1 1.2 4.7 0.4 2.5 9.1 9.3 2.0 0.2 STRC DFNB16 ENSG00000242866 Stereocilin Q7RTU9 15 43599563-43618800 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 9.0;pituitary gland: 4.4;retina: 3.6;testis: 5.0" "Cell type enhanced" "Detected in some" "Astrocytes: 10.1;Excitatory neurons: 55.7;Inhibitory neurons: 35.4;Oligodendrocyte precursor cells: 13.0;Oligodendrocytes: 15.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048083 Enhanced NA NA "Cluster 6: Brain - Smell perception" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA048083: AB_2732545" "unprognostic (8.60e-3)" "unprognostic (5.77e-3)" "unprognostic (6.14e-2)" "unprognostic (1.60e-2)" "unprognostic (1.47e-1)" "unprognostic (1.15e-3)" "unprognostic (1.65e-1)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.84e-2)" "unprognostic (5.92e-3)" "unprognostic (1.99e-4)" "unprognostic (1.58e-1)" "unprognostic (6.56e-2)" "unprognostic (1.78e-1)" "unprognostic (1.59e-4)" 0.1 0.6 3.5 0.0 3.8 0.0 0.3 9.0 8.0 0.3 0.3 0.3 0.1 0.1 1.0 0.2 0.4 0.0 0.1 3.8 2.4 0.5 0.6 0.1 0.0 3.8 2.2 0.6 0.2 0.0 4.4 0.0 3.7 1.0 0.0 3.6 0.7 0.0 0.4 0.7 0.4 0.0 1.5 0.3 0.3 5.0 3.2 0.6 1.0 0.0 0.0 0.1 0.3 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.8 9.0 8.0 3.8 2.4 3.8 2.2 3.7 1.5 3.2 4.8 0.2 0.0 0.0 10.1 0.0 0.6 0.1 0.2 0.0 2.6 0.6 0.9 0.3 0.0 0.2 0.0 6.2 0.3 0.0 0.1 0.0 0.1 0.5 0.3 0.1 0.2 0.0 0.0 55.7 0.2 0.1 0.1 0.0 0.3 0.0 2.0 0.4 0.3 0.1 3.3 35.4 0.2 0.0 0.3 0.2 0.5 0.0 0.1 1.8 6.5 0.0 2.3 0.0 13.0 15.4 0.2 1.3 0.4 0.1 0.2 0.7 0.1 0.3 8.7 0.0 0.2 0.1 4.5 0.9 0.0 0.4 0.7 0.2 0.0 0.1 0.0 STS "ARSC, ARSC1" ENSG00000101846 "Steroid sulfatase" P08842 X 7147237-7804358 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Pregnancy, Steroid metabolism" Hydrolase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 26.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 41.8;Excitatory neurons: 32.2;Inhibitory neurons: 39.3;Syncytiotrophoblasts: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 48.5;RPMI-8226: 69.8;U-266/70: 110.2;U-698: 47.2" "Low region specificity" "Detected in all" HPA002904 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA002904: AB_1080116" "unprognostic (1.09e-1)" "unprognostic (3.90e-2)" "unprognostic (1.44e-2)" "unprognostic (2.75e-1)" "unprognostic (6.72e-2)" "unprognostic (1.94e-2)" "unprognostic (2.62e-1)" "unprognostic (1.84e-1)" "unprognostic (8.23e-2)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (4.05e-2)" "unprognostic (2.78e-2)" "unprognostic (2.77e-1)" "unprognostic (2.56e-1)" "unprognostic (1.92e-2)" "unprognostic (1.34e-1)" 18.2 4.6 3.7 4.5 4.8 2.1 5.8 4.0 12.1 5.6 1.3 6.8 2.8 4.3 2.4 3.1 4.8 7.3 6.6 4.2 3.7 4.8 8.7 8.7 4.1 5.8 6.1 4.7 3.0 2.8 1.2 26.6 5.5 5.2 5.9 6.1 3.1 5.6 5.2 4.9 3.2 6.8 1.3 4.7 12.0 2.4 12.1 4.4 3.9 6.6 3.6 9.4 3.9 7.8 11.5 3.7 7.5 3.0 48.5 24.9 37.5 22.3 7.8 5.8 5.3 19.2 11.2 21.4 5.0 15.5 5.0 3.0 5.4 3.9 5.8 3.3 8.6 1.8 12.7 5.7 2.7 3.8 11.5 8.3 0.7 3.8 2.3 4.0 8.8 2.0 1.4 23.5 15.2 2.9 2.2 3.1 3.3 0.2 4.8 3.9 4.8 69.8 14.2 16.0 5.6 4.8 4.7 8.3 3.0 11.8 3.8 1.6 15.8 22.5 2.2 30.0 4.4 110.2 0.8 47.2 5.9 3.0 6.5 0.9 1.7 0.4 0.4 2.0 0.2 0.4 0.2 0.2 0.9 0.7 0.1 0.3 1.3 0.7 1.3 0.3 0.3 0.6 3.7 4.8 4.0 12.1 4.2 3.7 5.8 6.1 5.5 1.3 12.1 7.8 10.2 12.8 2.2 10.4 1.8 0.9 1.8 2.9 0.6 3.5 3.3 1.5 7.5 1.5 8.5 1.8 0.0 41.8 1.6 16.7 0.0 8.6 0.3 4.5 4.5 4.2 3.6 3.2 32.2 19.9 18.9 6.1 5.1 5.2 7.0 6.7 3.6 8.2 7.7 1.7 39.3 4.6 10.2 7.5 1.7 0.4 2.8 2.8 1.8 10.3 4.7 2.6 0.0 19.1 12.1 10.2 6.5 6.8 1.9 7.8 4.6 3.0 7.5 0.8 0.0 17.5 5.7 0.5 1.7 0.4 1.0 94.0 1.0 4.0 4.3 8.9 SUFU "PRO1280, SUFUH, SUFUXL" ENSG00000107882 "SUFU negative regulator of hedgehog signaling" Q9UMX1 10 102503972-102633535 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ciliopathy, Disease variant, Joubert syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 129.2;Late spermatids: 115.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008700 Supported Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA008700: AB_1080125" "unprognostic (1.55e-1)" "unprognostic (4.00e-2)" "unprognostic (5.14e-2)" "unprognostic (1.33e-1)" "unprognostic (4.69e-2)" "unprognostic (5.68e-2)" "unprognostic (3.69e-2)" "unprognostic (5.99e-2)" "unprognostic (1.64e-1)" "unprognostic (3.15e-3)" "unprognostic (9.60e-2)" "unprognostic (2.13e-1)" "unprognostic (3.72e-3)" "unprognostic (1.82e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-2)" "unprognostic (3.82e-3)" 6.6 7.2 8.8 7.1 8.5 2.0 6.1 8.9 8.0 8.6 5.5 6.8 3.9 7.4 4.9 9.2 7.1 6.6 6.3 7.8 7.3 6.1 6.2 5.8 7.2 8.3 8.2 8.9 4.1 11.1 4.3 7.4 7.8 8.5 4.4 4.6 7.1 5.2 8.6 14.4 5.7 7.3 6.7 7.4 4.6 11.5 8.0 7.8 3.4 7.3 8.1 8.8 9.2 7.3 8.7 9.1 14.4 20.8 14.5 12.1 7.0 8.8 17.0 12.5 11.3 8.5 6.3 8.9 24.5 9.9 5.0 6.0 17.8 9.8 8.2 5.5 13.8 21.2 5.2 8.0 6.9 7.7 14.6 13.9 7.5 9.3 7.5 22.9 16.3 8.5 4.8 7.9 7.8 7.2 14.8 11.6 4.1 5.6 6.7 15.8 15.5 4.7 8.3 12.8 4.8 7.8 7.0 6.4 8.1 13.1 14.2 5.0 18.1 5.5 7.8 6.0 9.8 6.4 4.5 6.4 6.9 14.9 3.8 2.0 2.0 2.9 1.0 2.4 0.8 0.9 1.2 1.1 1.9 0.8 0.8 1.0 0.4 1.1 2.5 1.1 0.8 1.4 8.8 8.5 8.9 8.0 7.8 7.3 8.3 8.2 7.8 6.7 8.0 7.3 3.3 0.0 3.7 28.7 4.9 3.1 2.1 2.9 6.8 4.2 3.5 3.0 4.0 1.5 4.6 3.7 8.4 7.8 3.1 3.5 1.9 4.4 129.2 4.5 6.2 5.1 1.2 2.5 25.9 3.0 3.5 6.0 4.6 8.5 3.8 3.8 10.8 5.4 12.4 1.7 22.2 2.2 0.0 9.4 6.3 115.9 5.0 8.7 0.0 32.8 7.8 2.7 4.1 17.6 16.8 4.1 1.3 6.8 4.0 2.0 5.7 5.8 5.7 4.8 0.0 3.0 4.5 8.7 5.3 8.9 6.5 7.0 7.1 7.6 3.0 1.3 SULT2B1 HSST2 ENSG00000088002 "Sulfotransferase family 2B member 1" O00204 19 48552172-48599425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 286.0;skin 1: 186.5;vagina: 145.9" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 62.3;Proximal enterocytes: 75.9;Squamous epithelial cells: 56.0;Suprabasal keratinocytes: 137.4;Urothelial cells: 114.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 74.2;MCF7: 46.8;OE19: 122.9;T-47d: 36.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041724, HPA043539, HPA076510" Enhanced Enhanced Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Vesicles Cytosol "HPA041724: AB_2677638, HPA043539: AB_2678540, HPA076510: " "unprognostic (6.55e-2)" "unprognostic (1.47e-1)" "unprognostic (5.28e-3)" "unprognostic (8.74e-2)" "unprognostic (5.00e-2)" "unprognostic (5.97e-2)" "unprognostic (4.43e-2)" "unprognostic (3.29e-3)" "unprognostic (1.62e-1)" "unprognostic (1.11e-2)" "unprognostic (2.54e-2)" "unprognostic (4.42e-2)" "unprognostic (5.01e-6)" "unprognostic (7.96e-3)" "unprognostic (1.32e-1)" "unprognostic (8.04e-2)" "unprognostic (2.77e-2)" 0.3 0.2 0.5 0.4 0.4 0.1 11.5 0.6 0.8 74.4 0.4 0.8 9.3 0.5 6.8 286.0 1.2 2.7 0.2 0.5 0.5 13.0 0.3 9.4 0.0 0.5 0.7 0.1 0.7 7.9 0.4 1.5 0.5 22.6 0.2 0.0 53.6 3.7 0.4 186.5 18.2 0.1 0.4 0.1 3.5 0.5 0.9 0.4 1.9 0.0 28.3 0.7 145.9 0.5 12.6 15.8 0.0 0.3 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.9 74.2 0.1 0.1 0.0 0.7 3.9 0.1 0.3 0.0 0.5 0.4 0.0 0.5 0.5 0.0 0.0 7.2 0.2 2.1 0.0 0.0 0.1 0.0 0.8 0.1 0.1 0.0 46.8 0.0 0.5 0.0 122.9 0.0 0.1 0.0 0.1 0.0 3.5 0.2 0.1 0.0 6.2 0.3 0.0 36.7 0.1 0.2 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.4 0.3 0.5 0.1 0.0 0.3 0.2 0.6 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.2 0.1 0.2 0.5 0.4 0.6 0.8 0.5 0.5 0.5 0.7 0.5 0.4 0.9 0.5 0.4 19.2 0.5 1.0 0.0 24.1 30.5 11.6 0.0 0.0 16.8 12.4 0.6 5.7 40.2 9.2 0.0 3.2 0.0 4.4 0.0 12.2 0.0 15.7 1.4 0.9 4.8 0.0 1.0 1.2 3.1 1.2 2.6 17.5 0.0 0.1 0.0 0.3 0.7 0.0 0.9 12.6 24.4 0.0 4.8 0.9 0.3 0.4 12.4 1.0 0.0 1.6 0.0 0.5 0.8 18.5 7.9 0.0 0.0 62.3 75.9 1.3 6.7 0.6 0.0 0.1 2.2 0.2 11.1 56.0 137.4 1.9 0.6 2.0 9.2 114.6 SUMO1 "GMP1, OFC10, PIC1, SMT3C, SMT3H3, SUMO-1, UBL1" ENSG00000116030 "Small ubiquitin like modifier 1" P63165 2 202206182-202238599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 7.6" "CAB004269, HPA056956" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Nuclear bodies" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear membrane" "Nucleoli, Nuclear bodies" "CAB004269: AB_628300, HPA056956: AB_2683285" "unprognostic (7.15e-2)" "unprognostic (2.34e-2)" "unprognostic (1.49e-1)" "unprognostic (2.52e-3)" "unprognostic (2.89e-1)" "unprognostic (9.56e-3)" "unprognostic (1.76e-2)" "unprognostic (8.08e-2)" "unprognostic (1.78e-3)" "prognostic favorable (7.93e-4)" "unprognostic (7.06e-3)" "unprognostic (1.16e-1)" "unprognostic (4.64e-3)" "unprognostic (1.31e-2)" "unprognostic (7.58e-2)" "unprognostic (2.82e-2)" "unprognostic (2.19e-1)" 77.5 99.1 79.4 62.7 84.9 133.7 83.6 89.0 99.9 68.9 84.4 82.7 72.0 65.1 86.3 71.6 65.7 71.7 79.8 85.6 85.3 118.1 174.1 66.5 86.4 79.9 80.1 54.5 55.8 91.6 56.7 75.6 81.1 75.3 82.8 80.2 66.8 61.9 107.5 57.1 80.5 71.5 78.9 68.1 73.8 54.7 81.4 112.1 102.3 103.3 95.4 77.9 54.9 86.6 164.1 82.4 291.4 155.8 159.3 168.5 129.7 171.0 214.6 209.0 274.6 178.1 203.7 111.6 153.5 199.0 193.5 117.1 242.2 237.9 325.0 104.8 185.7 207.6 159.0 211.2 114.9 237.2 188.5 130.9 225.2 164.0 123.9 195.1 197.3 219.0 194.2 176.0 226.4 141.1 298.3 391.6 351.7 168.5 172.2 190.9 163.2 197.9 255.5 134.3 201.7 219.3 140.3 133.6 236.4 313.9 120.0 223.2 139.9 152.5 153.0 141.4 152.8 151.7 322.9 285.8 170.2 165.4 137.2 242.2 220.0 284.2 169.2 226.5 179.6 276.3 206.8 200.0 223.6 231.6 193.8 202.3 256.5 246.5 239.7 187.8 329.0 394.7 79.4 84.9 89.0 99.9 85.6 85.3 79.9 80.1 81.1 78.9 81.4 86.6 182.7 112.2 61.1 10.7 143.1 422.1 204.4 448.6 177.6 99.6 196.8 170.2 58.1 130.1 215.3 189.4 64.6 259.4 162.3 136.6 481.3 250.4 91.3 148.3 115.1 170.7 142.4 140.1 31.4 173.3 297.8 161.8 89.7 115.2 92.6 114.7 142.8 202.1 205.3 87.5 27.8 156.4 319.4 140.7 330.2 28.0 129.8 137.7 211.7 15.9 241.3 182.3 176.1 16.6 21.2 208.1 191.1 127.9 130.5 258.5 272.2 534.4 185.5 87.8 111.7 92.5 221.9 212.0 141.5 183.9 424.5 209.7 174.5 134.9 157.5 254.1 SYNE1 "8B, ARCA1, C6orf98, CPG2, dJ45H2.2, enaptin, KIAA0796, MYNE1, Nesp1, Nesprin-1, SCAR8, SYNE-1B" ENSG00000131018 "Spectrin repeat containing nuclear envelope protein 1" Q8NF91 6 152121684-152637801 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" Actin-binding "Cancer-related genes, Disease variant, Emery-Dreifuss muscular dystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.5;choroid plexus: 182.9" "Cell type enhanced" "Detected in many" "Astrocytes: 550.1;Bipolar cells: 332.1;Excitatory neurons: 494.6;Inhibitory neurons: 482.6;Microglial cells: 315.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "eosinophil: 56.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 56.8" "Cell line enhanced" "Detected in many" "U-2 OS: 29.8;U-266/70: 29.1" "Low region specificity" "Detected in all" HPA019113 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA 72000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Nuclear membrane" "HPA019113: AB_1857707" "unprognostic (9.99e-2)" "unprognostic (1.91e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-1)" "unprognostic (2.28e-1)" "unprognostic (9.58e-3)" "unprognostic (1.11e-1)" "unprognostic (3.55e-3)" "unprognostic (1.58e-1)" "unprognostic (9.85e-2)" "unprognostic (8.87e-3)" "unprognostic (2.70e-1)" "unprognostic (4.14e-3)" "unprognostic (5.83e-2)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" 15.4 17.8 60.2 7.5 68.8 53.6 14.4 152.5 70.2 18.9 182.9 17.2 2.3 19.1 23.7 5.6 26.4 7.9 32.3 92.4 58.1 34.7 14.6 31.3 17.1 55.0 58.8 44.5 20.6 23.6 56.8 4.4 55.6 17.0 6.2 66.3 5.0 12.6 28.0 19.6 11.4 13.1 38.3 32.9 21.6 17.6 55.4 23.9 44.7 16.5 13.4 16.3 12.9 51.5 0.2 5.8 3.7 4.4 5.7 12.1 1.5 14.7 6.9 3.4 6.0 1.3 0.2 13.5 0.7 7.5 11.2 0.3 1.6 3.8 3.5 11.6 4.0 5.2 4.1 4.0 12.8 1.1 2.7 7.9 0.8 7.5 14.9 9.2 6.8 6.9 0.0 14.2 9.2 0.7 2.4 0.2 0.9 1.3 2.2 2.9 8.1 3.5 15.7 0.2 2.6 3.9 2.7 0.8 9.8 3.7 0.8 0.5 9.0 16.3 29.8 5.9 7.6 29.1 12.5 23.3 8.8 2.9 4.6 10.2 2.3 56.8 11.8 1.8 7.9 6.9 10.3 13.4 1.8 8.2 9.7 10.9 1.6 9.9 3.9 1.5 13.2 3.5 60.2 68.8 152.5 70.2 92.4 58.1 55.0 58.8 55.6 38.3 55.4 51.5 139.7 166.7 215.2 550.1 29.1 12.7 5.4 3.0 3.4 332.1 4.9 9.7 117.2 7.2 53.1 44.1 200.1 0.9 132.9 0.4 3.9 24.0 11.5 132.0 118.2 127.5 3.0 11.6 494.6 7.7 14.2 79.6 7.7 17.8 15.2 13.1 90.0 21.8 8.0 138.0 482.6 11.5 2.0 10.1 15.0 12.6 33.2 16.0 16.0 315.7 12.8 27.3 210.1 256.4 108.6 4.2 0.1 39.9 79.6 5.1 0.0 17.8 146.7 145.5 26.3 145.8 85.6 3.9 5.7 2.2 9.7 1.2 74.7 62.2 0.4 2.2 TAB2 "KIAA0733, MAP3K7IP2" ENSG00000055208 "TGF-beta activated kinase 1 (MAP3K7) binding protein 2" Q9NYJ8 6 149218641-149411613 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 238.0;Microglial cells: 188.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065436, HPA070137" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" "HPA065436: AB_2732735, HPA070137: AB_2732148" "unprognostic (1.08e-2)" "unprognostic (4.81e-3)" "unprognostic (1.27e-2)" "unprognostic (1.07e-2)" "unprognostic (7.05e-2)" "unprognostic (3.85e-1)" "unprognostic (1.85e-2)" "unprognostic (2.95e-3)" "unprognostic (2.05e-1)" "unprognostic (3.08e-2)" "unprognostic (3.08e-2)" "unprognostic (8.88e-2)" "unprognostic (1.08e-1)" "unprognostic (2.29e-3)" "unprognostic (1.93e-1)" "unprognostic (7.57e-2)" "unprognostic (2.49e-1)" 27.6 25.6 55.1 32.9 52.2 48.4 33.3 45.2 58.5 36.4 39.9 47.5 24.1 32.7 27.9 35.7 27.3 26.0 32.3 54.5 84.4 34.5 58.8 31.0 38.8 91.7 73.2 40.9 33.1 41.7 15.3 27.6 67.0 32.8 32.9 20.0 54.8 36.0 69.4 24.6 26.3 37.1 79.7 35.1 27.2 21.3 56.2 47.2 35.7 59.8 37.8 37.5 28.2 71.8 32.0 19.8 51.8 56.0 49.6 42.7 40.1 35.8 65.6 55.4 71.6 30.1 44.9 33.8 44.8 42.8 72.0 31.8 42.3 49.2 86.1 112.0 30.2 55.0 25.8 43.4 49.1 47.8 32.4 51.4 68.8 55.9 73.8 85.1 53.1 33.4 42.1 32.9 57.6 39.8 44.9 27.0 33.0 27.2 22.2 37.7 36.4 21.7 51.9 45.7 39.3 35.7 49.0 81.4 27.6 59.4 50.8 52.1 57.6 42.2 51.8 47.0 63.5 28.9 18.2 50.4 70.8 29.9 44.7 0.0 0.9 0.3 1.4 1.7 1.3 1.9 4.1 2.7 2.1 0.9 2.6 2.3 4.7 4.7 1.4 2.4 4.6 1.2 55.1 52.2 45.2 58.5 54.5 84.4 91.7 73.2 67.0 79.7 56.2 71.8 19.9 67.3 28.3 238.0 27.5 47.0 26.5 17.0 17.1 9.1 29.3 19.4 48.0 11.5 19.5 16.5 2.1 13.1 24.3 42.1 11.7 15.0 40.0 28.5 31.9 22.8 16.3 23.1 82.1 19.8 11.8 26.7 21.9 47.8 28.5 28.0 22.9 41.4 28.9 11.8 83.3 21.5 14.2 43.1 81.7 13.7 29.2 42.4 17.8 188.3 42.8 10.9 21.6 82.9 81.3 26.3 17.2 28.6 23.1 43.7 19.9 19.7 18.5 5.9 19.7 29.9 19.0 16.4 12.4 18.2 42.9 10.7 40.0 12.7 22.2 57.2 TAF6 "MGC:8964, TAF2E, TAFII70, TAFII80, TAFII85" ENSG00000106290 "TATA-box binding protein associated factor 6" P49848 7 100107070-100119841 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 72.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006566 Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "HPA006566: AB_1080194" "unprognostic (5.60e-2)" "unprognostic (3.11e-2)" "unprognostic (1.73e-2)" "unprognostic (2.10e-1)" "unprognostic (7.79e-2)" "unprognostic (4.20e-2)" "prognostic unfavorable (6.06e-5)" "unprognostic (2.02e-1)" "unprognostic (1.89e-1)" "unprognostic (1.29e-1)" "unprognostic (3.70e-3)" "unprognostic (1.68e-1)" "unprognostic (4.55e-2)" "unprognostic (1.95e-1)" "unprognostic (3.38e-1)" "unprognostic (4.78e-1)" "unprognostic (1.37e-1)" 24.2 37.0 28.9 23.4 29.2 23.4 24.4 24.1 42.7 39.5 23.8 38.9 17.2 42.9 21.9 27.3 34.9 20.5 32.2 31.3 25.2 30.9 20.6 24.8 22.6 25.2 23.2 41.2 23.0 30.5 41.1 24.9 24.4 30.7 19.5 19.2 25.5 31.1 45.0 26.5 28.0 33.9 19.0 28.3 28.0 38.5 25.4 29.3 32.9 35.8 25.7 37.3 29.9 25.6 55.1 101.8 64.4 105.7 84.1 44.5 89.3 60.0 66.4 77.2 70.6 76.1 65.6 50.4 65.5 92.7 130.4 45.7 90.6 73.2 81.3 82.0 57.0 49.4 99.3 50.8 86.6 46.2 43.5 46.4 44.5 111.0 121.7 61.0 63.0 87.7 84.6 89.0 69.2 194.4 101.1 76.9 94.7 50.1 82.4 73.2 78.7 75.0 54.5 44.8 57.9 84.4 73.7 115.3 49.3 93.2 42.1 47.2 60.4 113.2 114.6 146.2 77.6 55.0 104.0 85.1 74.9 65.7 99.2 17.2 13.5 17.5 18.0 14.4 21.5 11.9 17.3 18.3 17.6 17.9 17.0 16.3 7.1 18.8 35.3 10.3 18.3 17.5 28.9 29.2 24.1 42.7 31.3 25.2 25.2 23.2 24.4 19.0 25.4 25.6 13.0 9.6 11.8 10.1 15.4 11.3 21.0 25.1 12.5 12.7 13.2 15.9 0.9 18.6 15.7 25.8 0.0 72.1 13.0 12.9 17.6 25.7 28.3 20.7 18.5 14.8 15.6 12.8 12.6 16.6 34.5 16.3 18.3 14.6 0.0 25.6 13.6 6.1 20.9 13.5 10.7 11.9 26.4 8.8 6.9 50.7 21.8 12.3 12.4 3.7 18.7 18.7 18.6 6.0 7.3 14.9 18.7 31.2 12.8 13.0 14.2 25.8 21.8 14.0 26.3 14.6 23.8 25.5 52.3 15.4 11.8 34.5 18.3 16.2 17.4 14.4 TAPT1 FLJ90013 ENSG00000169762 "Transmembrane anterior posterior transformation 1" Q6NXT6 4 16160505-16227410 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Chondrogenesis, Cilium biogenesis/degradation, Differentiation, Host-virus interaction, Osteogenesis" "Developmental protein, Receptor" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 114.7;Late spermatids: 163.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "REH: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042567 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Centrosome "Nucleoplasm, Cytosol" "HPA042567: AB_2678055" "unprognostic (2.34e-1)" "unprognostic (5.84e-2)" "unprognostic (1.41e-2)" "prognostic favorable (9.75e-4)" "unprognostic (2.43e-1)" "unprognostic (2.56e-2)" "unprognostic (2.32e-3)" "unprognostic (3.15e-3)" "unprognostic (1.54e-1)" "unprognostic (6.30e-2)" "prognostic favorable (5.34e-4)" "unprognostic (7.07e-2)" "prognostic favorable (8.52e-4)" "unprognostic (9.00e-2)" "unprognostic (8.52e-2)" "unprognostic (7.25e-3)" "prognostic favorable (4.18e-4)" 7.4 15.1 17.5 6.0 18.6 25.7 10.0 17.3 22.3 8.2 15.1 8.9 6.4 10.0 9.2 6.1 9.5 6.7 9.1 17.1 17.0 12.4 30.5 11.9 9.6 18.6 17.4 8.1 8.1 13.0 8.5 6.8 18.4 7.4 8.2 24.7 7.6 6.4 35.5 7.7 7.5 9.3 17.4 8.5 7.9 11.1 17.5 12.2 11.5 19.9 8.1 7.6 6.9 19.5 4.9 3.6 6.0 7.0 8.9 6.8 2.5 7.8 6.0 7.4 8.1 4.9 8.5 31.7 8.3 5.0 10.8 4.0 5.2 4.0 9.3 2.9 6.3 6.2 5.0 5.2 8.4 12.6 6.2 4.2 7.7 7.3 5.3 9.1 3.8 19.3 9.7 14.5 7.2 3.5 18.7 10.1 4.0 9.3 8.4 45.0 8.4 5.8 12.0 5.1 10.0 8.0 7.4 6.2 9.5 4.1 11.5 12.3 7.1 6.2 4.1 4.2 10.3 13.9 12.2 24.2 12.4 30.9 7.3 1.1 0.3 0.0 0.2 0.2 0.0 1.0 0.7 0.4 0.5 2.5 0.9 0.7 0.6 0.3 0.3 0.8 0.5 0.3 17.5 18.6 17.3 22.3 17.1 17.0 18.6 17.4 18.4 17.4 17.5 19.5 12.0 32.1 62.6 47.3 20.2 9.1 6.3 4.2 4.0 24.5 15.0 9.9 14.3 10.0 8.7 7.3 114.7 4.2 16.2 11.1 3.9 6.7 79.0 14.2 12.6 12.8 14.4 16.6 42.6 8.2 3.1 10.2 8.6 12.0 2.5 17.5 8.6 46.0 4.2 70.7 43.6 9.8 4.1 10.3 18.9 163.1 9.9 11.1 16.0 45.0 6.5 33.1 8.2 60.8 68.2 9.5 9.4 15.1 8.9 7.1 10.7 8.7 14.4 62.4 6.6 17.0 11.5 33.3 5.7 7.1 8.0 7.0 10.8 16.5 9.0 6.6 TBC1D20 "C20orf140, dJ852M4.2" ENSG00000125875 "TBC1 domain family member 20" Q96BZ9 20 423596-462566 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 147.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043613 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" "HPA043613: AB_10963930" "unprognostic (2.16e-3)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.14e-2)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (3.68e-3)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" "unprognostic (2.54e-2)" "unprognostic (1.35e-2)" "unprognostic (1.57e-1)" "unprognostic (1.20e-3)" "unprognostic (2.97e-1)" "unprognostic (2.20e-1)" "unprognostic (2.21e-1)" "unprognostic (9.52e-2)" 16.8 21.5 21.7 7.6 24.2 7.0 16.0 22.6 22.4 18.4 17.0 19.1 8.6 17.4 15.6 18.9 16.1 11.8 16.6 20.4 21.6 14.4 13.4 18.1 10.6 23.1 23.6 17.3 14.7 21.2 17.8 17.5 22.2 17.7 11.8 7.7 16.9 18.8 20.4 20.0 14.5 20.4 22.3 16.1 15.4 9.9 23.0 14.6 15.0 23.6 12.9 19.6 16.8 23.4 18.5 12.6 18.2 15.9 75.9 39.3 16.3 19.8 39.1 27.7 29.4 11.8 9.6 8.4 4.6 43.7 35.2 18.1 18.8 20.2 26.8 4.9 4.9 13.4 4.0 27.3 45.7 13.1 7.1 35.2 38.3 15.4 14.4 29.9 17.7 14.4 14.8 17.7 30.7 4.5 12.1 15.5 10.6 23.7 11.0 12.0 17.2 10.4 18.7 12.0 15.8 12.8 22.2 39.9 53.5 20.0 14.1 27.9 19.9 25.0 8.9 22.2 14.3 9.7 19.0 7.7 13.4 14.0 15.9 3.0 0.6 0.7 1.8 0.5 1.2 0.8 1.2 2.1 0.6 0.7 1.1 1.8 1.5 0.9 0.4 0.6 0.8 0.7 21.7 24.2 22.6 22.4 20.4 21.6 23.1 23.6 22.2 22.3 23.0 23.4 23.0 12.8 13.6 16.3 22.6 18.5 13.6 11.3 23.3 29.3 22.4 14.4 16.8 24.3 11.1 14.7 12.5 16.5 28.9 29.6 11.7 23.8 48.9 21.3 26.9 20.7 16.1 48.6 16.2 30.3 25.1 23.0 17.9 16.2 11.4 14.4 25.4 19.7 19.7 26.9 19.2 17.9 8.2 17.6 16.4 147.2 29.5 18.6 14.2 14.0 13.2 21.4 43.3 11.6 15.2 22.5 20.7 35.3 30.0 21.2 19.4 17.0 17.1 19.4 19.7 22.1 18.3 33.1 34.7 15.3 18.9 50.9 24.0 19.6 15.7 27.9 TBC1D24 "DFNA65, DFNB86, KIAA1171, TLDC6" ENSG00000162065 "TBC1 domain family member 24" Q9ULP9 16 2475051-2509560 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Deafness, Disease variant, Epilepsy, Mental retardation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 16.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 43.8;Inhibitory neurons: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SCLC-21H: 34.7" "HPA044712, HPA068080" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cell Junctions" "HPA044712: AB_10795619, HPA068080: AB_2685948" "prognostic unfavorable (3.22e-4)" "unprognostic (5.23e-2)" "unprognostic (4.02e-2)" "unprognostic (6.41e-2)" "unprognostic (3.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.40e-1)" "unprognostic (2.03e-2)" "unprognostic (1.68e-1)" "unprognostic (7.37e-2)" "unprognostic (4.37e-2)" "unprognostic (1.28e-1)" "unprognostic (4.66e-3)" "unprognostic (2.02e-2)" "unprognostic (8.19e-2)" "unprognostic (7.78e-3)" "unprognostic (1.61e-1)" 3.8 3.3 7.5 1.8 8.1 2.5 2.8 3.6 10.5 2.1 0.0 2.0 2.2 1.4 2.8 1.0 2.3 1.9 3.0 8.3 3.7 4.3 3.7 3.9 1.8 2.9 2.9 1.0 10.6 1.9 2.6 2.1 3.1 2.5 0.9 4.2 16.5 3.5 3.4 1.2 1.6 1.7 1.9 2.0 2.2 1.2 4.4 0.9 3.1 1.7 1.2 1.8 0.9 2.8 3.4 6.7 4.5 9.2 5.1 5.1 3.8 6.2 3.3 4.0 3.5 6.2 2.9 8.6 5.2 4.9 1.9 6.3 7.1 2.0 2.9 9.3 8.0 8.0 9.5 5.5 3.1 5.9 3.2 1.9 2.8 3.5 1.4 2.8 5.1 3.3 9.9 4.8 3.8 6.4 4.1 11.9 4.0 3.2 4.3 20.9 8.5 6.1 2.9 2.3 34.7 8.5 3.8 15.3 2.6 1.6 4.8 5.2 5.4 7.8 8.4 7.9 6.2 3.2 3.0 11.0 3.4 8.5 7.2 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 7.5 8.1 3.6 10.5 8.3 3.7 2.9 2.9 3.1 1.9 4.4 2.8 4.7 28.9 26.7 15.7 1.9 0.5 3.0 1.4 1.8 19.0 17.8 10.8 6.9 10.0 6.9 5.5 43.8 1.5 5.6 2.4 33.2 5.0 0.2 2.8 10.0 5.4 11.4 6.5 29.6 6.1 1.0 5.8 5.6 4.0 3.8 6.0 10.4 17.3 3.5 26.9 34.0 2.6 6.1 5.1 3.3 1.0 9.0 3.0 1.8 6.5 3.6 13.8 6.2 25.1 9.7 5.0 2.8 6.0 1.7 3.1 1.8 3.9 3.6 25.5 0.0 11.2 3.7 8.8 5.9 1.4 1.4 0.3 2.9 3.4 4.7 1.6 TBC1D7 "dJ257A7.3, FLJ32666" ENSG00000145979 "TBC1 domain family member 7" Q9P0N9 6 13266542-13328583 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "melanoma: 13.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 320.4;U-266/84: 174.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034748 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "HPA034748: AB_10671232" "unprognostic (9.53e-2)" "unprognostic (8.39e-2)" "unprognostic (3.18e-1)" "unprognostic (1.81e-2)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (3.95e-3)" "unprognostic (5.54e-2)" "unprognostic (9.30e-2)" "prognostic favorable (4.98e-5)" "unprognostic (4.36e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (2.03e-7)" "unprognostic (1.57e-1)" "unprognostic (3.46e-2)" "unprognostic (3.48e-1)" "unprognostic (2.78e-2)" 9.4 12.0 14.3 9.7 15.9 26.5 11.5 13.0 26.3 10.8 9.9 15.2 14.5 8.4 20.0 17.1 6.6 10.3 31.7 14.3 12.9 21.4 17.5 11.0 13.9 11.8 11.6 7.7 10.2 12.4 10.7 14.4 13.4 12.4 16.5 11.5 12.2 7.0 16.2 13.8 10.8 10.1 10.7 12.3 9.8 14.0 12.7 16.9 8.0 14.5 15.6 10.0 11.4 15.8 26.2 25.5 36.0 36.8 27.5 15.7 24.9 11.5 13.3 24.0 26.8 51.8 23.0 18.1 75.0 19.3 55.8 20.8 24.5 29.0 21.9 28.4 29.1 50.3 16.5 45.8 63.6 32.7 73.6 21.4 40.6 29.7 19.3 24.0 40.5 57.2 57.3 23.7 30.8 42.8 42.2 78.5 24.4 32.4 24.6 61.7 15.7 77.7 54.1 35.1 69.4 30.8 28.4 55.4 320.4 71.3 53.6 19.1 29.4 24.6 30.8 13.6 16.2 55.8 174.2 86.2 23.1 34.1 51.1 28.2 21.6 27.0 11.6 20.0 7.6 15.4 9.9 10.5 43.3 14.5 9.1 11.1 42.2 21.4 13.7 42.2 14.6 10.4 14.3 15.9 13.0 26.3 14.3 12.9 11.8 11.6 13.4 10.7 12.7 15.8 11.0 12.8 13.9 3.9 16.2 7.5 9.9 37.2 11.4 6.5 15.7 20.6 30.6 15.7 28.8 16.5 4.2 41.0 15.0 12.9 33.2 16.4 8.1 15.2 12.7 12.4 9.0 57.4 8.4 14.3 23.3 9.9 15.8 15.7 9.5 14.4 12.1 15.2 24.2 10.1 9.5 18.3 50.8 12.9 23.0 5.8 4.4 31.3 10.6 4.7 13.9 8.9 13.4 6.6 7.3 22.2 18.3 5.3 21.9 11.6 13.1 56.1 16.4 8.0 13.1 5.6 20.2 14.7 34.3 21.7 8.9 46.9 11.3 14.4 16.4 13.4 TBCE "HRD, KCS, KCS1, pac2" ENSG00000284770 "Tubulin folding cofactor E" Q15813 1 235367360-235452443 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Dwarfism, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 14 "Cardiomyocytes: 16.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "HPA026552, HPA026557" Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA026552: AB_1857797, HPA026557: AB_1857798" 2.8 4.1 2.1 2.4 2.0 2.1 2.5 2.9 4.1 2.7 1.9 3.8 2.7 2.5 0.6 3.5 1.8 2.3 5.1 1.9 2.0 3.6 5.5 1.9 2.2 2.2 2.0 2.0 1.6 3.0 3.2 2.1 2.6 3.3 4.5 3.3 1.9 7.9 2.1 1.3 2.0 1.9 1.9 3.7 1.7 2.1 2.1 6.8 1.6 2.8 2.7 2.1 14.5 26.9 12.6 7.9 14.1 15.8 11.2 20.3 9.9 21.6 26.9 23.0 11.1 14.7 36.6 8.7 14.4 7.6 18.6 12.6 16.5 24.8 28.2 15.7 11.4 17.8 20.4 25.0 10.8 17.1 11.7 17.1 17.8 7.9 10.9 18.2 60.5 6.5 21.4 7.6 9.2 10.6 23.8 40.3 2.3 14.1 26.7 30.4 21.2 11.4 10.5 6.5 15.4 8.3 16.9 12.0 21.7 14.0 12.8 13.9 8.7 18.0 17.8 9.8 29.1 16.8 11.4 14.8 20.8 0.3 0.8 0.6 0.5 1.7 0.5 0.1 0.5 0.4 0.9 0.4 0.1 0.3 0.1 0.3 0.7 0.2 0.3 0.4 2.1 2.0 2.9 4.1 1.9 2.0 2.2 2.0 2.1 1.9 2.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBCE "HRD, KCS, KCS1, pac2" ENSG00000285053 "Tubulin folding cofactor E" Q15813 1 235328570-235448952 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Dwarfism, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA026552, HPA026557" Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "HPA026552: AB_1857797, HPA026557: AB_1857798" 0.9 0.7 1.1 1.3 0.8 1.3 0.8 2.4 1.7 0.8 0.1 1.0 0.8 1.5 0.5 0.6 0.7 0.6 1.1 1.0 1.3 1.2 0.7 0.8 1.5 1.9 1.1 1.9 1.6 0.8 1.3 2.2 1.2 0.9 1.9 0.7 0.8 3.5 0.8 1.4 0.7 0.5 1.0 1.2 1.6 1.4 2.4 1.0 2.4 1.2 0.9 1.7 8.4 2.5 8.9 5.7 1.5 2.4 5.9 3.7 1.9 6.3 3.3 2.2 6.6 4.4 9.0 1.5 3.8 3.9 3.4 3.2 4.5 6.3 6.7 2.2 3.5 2.8 0.6 5.6 5.2 0.8 1.0 3.4 3.9 1.3 2.3 5.2 6.2 2.3 3.9 4.2 8.1 2.0 10.0 4.8 1.9 5.2 3.8 2.0 2.2 2.7 9.3 8.5 3.6 6.4 4.0 1.3 9.5 10.8 3.5 4.6 7.8 4.5 5.2 5.6 6.5 5.8 6.2 2.5 6.0 3.0 2.5 2.4 2.3 2.9 2.4 1.8 2.0 2.4 2.6 1.3 2.4 2.1 0.5 1.8 2.5 1.8 2.7 2.1 1.1 0.8 2.4 1.7 1.0 1.3 1.9 1.1 2.2 0.5 1.4 1.7 10.1 0.0 5.9 17.9 8.9 3.1 5.2 8.2 5.2 9.2 6.9 9.4 0.0 4.3 7.0 7.3 4.2 0.0 8.6 4.3 0.0 3.5 10.9 3.4 12.3 5.9 3.5 6.9 22.4 1.6 0.0 5.5 9.7 4.3 3.8 7.7 2.2 5.9 0.0 6.7 26.1 5.3 4.1 4.7 2.7 6.2 10.8 6.6 8.8 10.3 8.9 8.9 11.3 11.6 22.0 3.1 4.1 7.5 6.6 2.9 5.2 1.4 5.7 13.1 0.0 5.9 7.6 14.0 8.8 7.5 2.8 0.0 8.8 8.5 8.3 3.9 TBCK "HSPC302, MGC16169" ENSG00000145348 "TBC1 domain containing kinase" Q8TEA7 4 106041599-106316683 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 134.8;Excitatory neurons: 196.6;Inhibitory neurons: 221.1;Microglial cells: 128.4;Oligodendrocyte precursor cells: 147.2;Oligodendrocytes: 188.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+ SV40 Large T+: 44.0;BJ hTERT+ SV40 Large T+ RasG12V: 81.7;HBF TERT88: 59.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039951, HPA051611" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli fibrillar center" "HPA039951: AB_10795300, HPA051611: AB_2681550" "unprognostic (1.65e-1)" "unprognostic (2.60e-2)" "unprognostic (8.47e-2)" "unprognostic (1.12e-1)" "unprognostic (8.06e-2)" "unprognostic (1.13e-3)" "unprognostic (1.55e-1)" "unprognostic (3.81e-1)" "unprognostic (8.68e-2)" "unprognostic (1.85e-1)" "unprognostic (3.67e-2)" "unprognostic (1.80e-1)" "prognostic favorable (3.20e-4)" "unprognostic (8.17e-3)" "unprognostic (1.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.29e-1)" 7.4 5.2 5.6 3.0 5.3 1.3 3.4 11.0 6.1 4.5 8.3 3.2 2.3 4.3 6.0 4.2 5.3 5.6 2.8 6.1 7.0 6.3 4.4 4.1 3.0 5.2 5.3 6.4 5.8 4.8 3.9 5.5 6.0 4.7 3.1 7.6 3.6 6.0 1.6 4.1 3.3 4.7 3.5 3.6 3.5 6.1 6.9 4.7 5.5 4.3 2.6 5.2 3.0 10.1 1.4 5.9 9.0 2.7 36.7 19.1 1.1 8.1 8.9 44.0 81.7 10.9 6.4 2.3 13.0 28.0 7.0 5.4 5.7 8.1 59.3 5.1 1.8 14.1 4.5 10.3 9.7 2.7 6.3 20.9 5.9 4.1 7.1 14.5 11.1 6.0 7.2 3.8 10.2 7.7 5.2 3.7 2.0 14.4 2.0 4.1 3.7 6.8 11.1 9.0 4.4 4.1 8.2 4.0 5.6 7.6 4.8 8.5 8.3 7.7 4.3 2.4 4.4 2.5 6.1 6.8 10.1 5.6 5.0 14.1 5.1 5.1 4.7 5.7 5.6 4.8 4.9 6.4 4.8 7.9 5.6 5.2 0.4 5.2 3.8 4.4 5.5 4.0 5.6 5.3 11.0 6.1 6.1 7.0 5.2 5.3 6.0 3.5 6.9 10.1 7.7 19.2 25.2 134.8 13.9 2.3 6.4 9.0 17.1 20.7 8.2 6.9 8.2 5.7 15.5 14.7 20.9 11.5 9.0 3.5 3.9 4.3 45.7 10.2 15.9 8.9 5.4 9.2 196.6 0.9 6.6 12.5 15.3 21.1 11.4 21.5 8.6 4.6 6.8 11.8 221.1 5.7 10.2 6.2 1.6 28.2 11.1 7.7 5.4 128.4 4.6 8.1 10.3 147.2 188.8 2.2 8.0 12.8 10.4 4.3 4.8 8.0 11.9 15.3 0.0 10.6 9.6 14.5 8.2 14.2 2.4 7.4 10.6 13.9 5.5 4.5 TBL1XR1 "C21, DC42, FLJ12894, IRA1, TBLR1" ENSG00000177565 "TBL1X receptor 1" Q9BZK7 3 177019340-177228000 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 280.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019182 Supported Approved Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA019182: AB_1857800" "unprognostic (4.11e-2)" "unprognostic (3.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.27e-3)" "prognostic favorable (5.16e-5)" "unprognostic (4.44e-2)" "prognostic unfavorable (1.08e-7)" "unprognostic (3.75e-1)" "unprognostic (4.84e-2)" "unprognostic (3.04e-1)" "unprognostic (3.13e-3)" "unprognostic (2.50e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (5.83e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" 18.8 20.3 7.2 24.4 12.7 30.2 21.7 13.9 11.8 24.9 8.5 31.0 24.6 16.9 9.2 21.2 22.4 23.2 32.6 16.0 3.3 22.3 24.5 19.6 31.3 8.1 8.5 20.9 12.1 27.3 2.9 21.0 4.9 25.6 24.4 42.7 16.1 14.8 12.9 17.1 18.7 19.4 8.6 22.9 22.3 19.1 8.4 45.5 47.1 25.3 36.3 25.3 10.3 15.0 96.8 41.2 61.1 39.7 56.2 65.8 44.2 26.1 52.3 30.3 36.3 48.9 76.2 98.9 132.9 43.6 58.4 61.2 42.9 63.2 58.7 97.5 14.5 56.2 66.8 30.3 49.7 91.0 29.6 95.3 35.9 37.3 90.6 53.8 48.5 68.5 44.8 189.9 42.8 31.0 81.7 14.0 38.1 59.8 32.2 53.9 72.6 124.6 33.1 119.5 24.8 38.7 43.3 35.9 49.8 37.3 113.0 74.3 60.5 48.9 35.3 28.8 65.6 89.8 117.6 280.7 32.9 66.2 56.1 14.3 3.7 3.8 5.6 6.2 5.9 7.5 6.9 7.3 4.6 7.3 5.9 7.4 12.9 7.4 5.5 12.4 8.3 5.3 7.2 12.7 13.9 11.8 16.0 3.3 8.1 8.5 4.9 8.6 8.4 15.0 55.1 73.7 60.7 128.0 56.5 91.5 55.1 90.6 62.0 113.6 69.2 42.2 101.9 47.1 80.3 104.8 125.1 28.9 70.0 84.7 29.4 52.2 7.4 90.9 59.0 65.5 85.3 60.4 228.9 43.8 35.1 81.8 44.4 134.5 25.3 65.9 48.5 66.6 37.8 116.1 167.6 72.6 59.0 91.1 75.0 9.0 64.0 69.4 65.8 184.6 55.8 47.6 41.2 241.8 269.4 66.7 43.7 73.0 75.1 144.9 41.5 67.3 83.9 81.6 46.0 76.3 54.4 12.9 61.4 88.1 111.8 27.5 66.0 41.6 84.6 83.6 TBX1 "CATCH22, VCF" ENSG00000184058 "T-box transcription factor 1" O43435 22 19756703-19783593 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 61.5;tongue: 36.5" "Cell type enriched" "Detected in many" 4 "Late spermatids: 181.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 24.6;K-562: 121.6;NB-4: 28.6;TIME: 40.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA029330 Approved "Nuclear bodies,Cytoplasmic bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear bodies, Cytoplasmic bodies" "HPA029330: AB_2673002" "unprognostic (2.54e-1)" "unprognostic (4.28e-3)" "unprognostic (7.53e-3)" "unprognostic (1.59e-1)" "unprognostic (4.03e-2)" "unprognostic (2.63e-3)" "unprognostic (1.16e-1)" "unprognostic (2.53e-1)" "unprognostic (5.48e-2)" "unprognostic (1.18e-1)" "unprognostic (4.42e-2)" "unprognostic (2.25e-2)" "unprognostic (8.30e-3)" "unprognostic (9.14e-2)" "unprognostic (4.44e-1)" "unprognostic (8.31e-2)" "prognostic favorable (8.90e-4)" 4.0 0.6 0.5 1.0 0.7 0.1 8.0 0.6 0.8 7.4 0.8 1.8 0.7 2.6 0.2 3.0 7.7 0.4 0.8 0.2 0.2 0.4 0.4 4.3 2.9 0.6 0.2 2.2 0.3 7.6 0.7 0.1 0.5 5.2 0.3 0.0 8.1 0.5 61.5 10.6 3.0 0.6 0.0 0.6 1.2 16.8 0.9 0.0 11.2 36.5 1.2 2.7 7.1 1.0 15.3 1.4 0.2 10.7 0.0 0.0 2.1 0.2 0.0 0.0 0.0 1.1 0.1 0.3 0.3 0.3 1.5 0.8 12.0 10.4 0.0 0.6 24.6 0.2 2.9 0.0 0.0 0.1 0.1 0.1 0.1 2.4 0.0 0.0 0.0 0.5 121.6 0.0 7.7 2.8 0.3 28.6 1.7 0.0 16.8 0.3 10.6 0.1 0.0 0.0 1.5 0.4 0.0 0.2 0.0 3.1 5.1 7.7 40.0 0.1 0.4 0.2 0.2 0.3 0.5 0.1 0.0 0.2 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.6 0.8 0.2 0.2 0.6 0.2 0.5 0.0 0.9 1.0 11.4 0.0 2.8 0.0 0.3 2.4 1.6 3.3 0.0 0.6 1.1 0.9 2.4 0.0 1.6 0.0 0.0 0.2 0.6 0.1 0.0 0.0 43.3 0.2 0.1 7.5 0.0 0.0 0.3 0.2 1.7 1.5 0.0 0.2 2.5 0.1 2.5 0.0 2.0 0.0 0.9 1.0 6.1 1.3 3.6 181.9 2.5 1.0 0.0 0.0 0.1 0.3 2.1 0.0 0.0 0.1 0.0 2.2 0.0 1.0 0.1 0.0 2.3 0.1 0.0 1.1 0.8 1.9 12.8 0.3 2.4 0.1 0.7 0.0 0.2 2.0 TBX15 TBX14 ENSG00000092607 "T-box transcription factor 15" Q96SF7 1 118883046-118989556 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 46.8;skeletal muscle: 132.2;tongue: 114.7" "Cell type enhanced" "Detected in some" "Early spermatids: 8.2;Fibroblasts: 11.1;Hepatocytes: 15.3;Melanocytes: 7.2;Skeletal myocytes: 13.1;Smooth muscle cells: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 52.6;ASC TERT1: 22.1;BJ hTERT+ SV40 Large T+ RasG12V: 20.4;fHDF/TERT166: 28.2;HSkMC: 37.9;RH-30: 29.1;U-2197: 27.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.3" "HPA052245, HPA053713" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Centrosome "HPA052245: AB_2681771, HPA053713: " "unprognostic (1.94e-1)" "unprognostic (2.75e-3)" "unprognostic (1.92e-2)" "unprognostic (3.94e-2)" "unprognostic (5.72e-3)" "unprognostic (7.79e-2)" "unprognostic (5.82e-2)" "unprognostic (2.46e-1)" "unprognostic (3.00e-3)" "unprognostic (1.39e-1)" "unprognostic (3.81e-3)" "unprognostic (5.03e-2)" "prognostic unfavorable (5.57e-8)" "unprognostic (2.63e-2)" "unprognostic (3.90e-2)" "unprognostic (1.88e-3)" "unprognostic (2.31e-1)" 29.8 0.1 0.8 0.0 1.0 0.0 16.1 0.7 1.3 0.1 2.1 0.1 0.0 0.2 0.1 1.9 0.4 0.5 3.1 0.7 0.6 1.0 46.8 0.6 2.7 0.6 0.7 0.1 0.1 0.5 1.5 0.1 0.7 1.4 0.0 0.2 6.9 0.0 132.2 9.4 0.1 0.1 0.5 0.0 0.1 0.7 0.9 0.3 1.9 114.7 1.3 0.4 0.3 0.7 1.4 0.0 0.0 0.0 52.6 22.1 0.0 4.7 6.4 12.3 20.4 0.0 0.0 0.0 2.6 28.2 0.0 0.0 0.0 0.0 4.9 0.0 0.3 0.0 1.4 0.0 0.1 0.4 0.0 37.9 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 14.1 0.0 0.0 0.2 2.3 0.0 0.2 0.0 29.1 0.4 3.0 1.4 0.6 0.0 1.6 0.0 0.6 0.6 0.0 0.6 0.0 6.6 4.0 27.3 0.2 0.4 0.2 0.0 13.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.7 1.3 0.7 0.6 0.6 0.7 0.7 0.5 0.9 0.7 3.2 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 8.2 0.1 0.0 1.2 0.0 0.0 0.3 0.0 0.0 11.1 0.0 0.1 0.0 0.0 0.0 15.3 0.1 0.0 0.2 0.0 0.0 0.0 4.0 1.1 0.0 0.1 7.2 1.9 0.0 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.1 12.5 0.2 0.4 0.0 2.0 0.0 0.3 0.1 0.0 0.0 TBX18 ENSG00000112837 "T-box transcription factor 18" O95935 6 84687351-84764598 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.3" "Cell type enriched" "Detected in some" 5 "Microglial cells: 91.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 57.4;ASC diff: 39.0;ASC TERT1: 40.4;RH-30: 37.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA006807 Supported Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA006807: " "unprognostic (8.04e-2)" "unprognostic (7.06e-3)" "unprognostic (9.71e-2)" "unprognostic (2.31e-1)" "unprognostic (4.00e-1)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (3.24e-1)" "unprognostic (2.57e-1)" "unprognostic (7.92e-2)" "unprognostic (3.50e-1)" "unprognostic (1.12e-1)" "unprognostic (1.88e-14)" "unprognostic (4.81e-5)" "unprognostic (1.86e-1)" "unprognostic (3.07e-3)" "unprognostic (1.78e-1)" 10.3 2.0 1.6 0.9 3.1 0.0 6.1 1.1 3.4 1.9 4.6 0.7 0.1 1.4 0.4 3.1 1.8 1.5 6.6 1.3 1.3 0.4 0.2 0.3 1.8 1.7 1.2 2.7 0.5 0.4 1.6 1.8 1.6 0.6 0.4 0.1 1.6 1.1 1.3 4.7 1.1 0.5 1.5 0.0 0.4 1.0 2.1 0.6 1.7 1.4 0.2 4.5 2.9 1.7 0.0 57.4 0.0 0.0 39.0 40.4 0.0 23.5 11.5 17.4 16.5 0.4 0.0 0.1 0.0 9.8 0.0 3.0 0.0 13.8 14.0 0.0 23.2 0.0 0.0 0.0 5.0 0.0 23.1 17.1 1.3 12.1 25.8 0.0 20.2 0.0 30.7 0.2 12.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 37.3 0.0 0.3 0.0 0.2 1.2 0.0 1.0 9.0 1.4 0.0 31.0 18.2 0.0 4.8 17.6 0.0 0.3 0.0 0.0 10.9 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.1 1.1 3.4 1.3 1.3 1.7 1.2 1.6 1.5 2.1 1.7 1.6 0.0 0.0 0.3 0.0 5.5 0.0 0.4 0.0 0.0 0.2 0.3 2.3 0.0 0.3 0.0 0.0 0.1 0.1 0.2 0.0 0.0 6.9 0.0 0.1 1.6 0.0 0.0 0.1 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.4 0.0 2.1 6.1 2.3 1.2 0.1 8.8 91.8 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.0 1.0 0.1 0.2 0.1 0.0 1.6 16.9 0.4 3.1 0.1 4.4 0.1 0.8 0.8 0.3 0.0 TBX20 ENSG00000164532 "T-box transcription factor 20" Q9UMR3 7 35202430-35254100 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "heart muscle: 35.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "medulla oblongata: 1.2;pons: 3.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.2;HEL: 3.2;HHSteC: 3.4;HMC-1: 3.9;RH-30: 3.8;SH-SY5Y: 7.4;WM-115: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA007840 Approved "Nucleoli fibrillar center" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoli fibrillar center" "HPA007840: " "unprognostic (2.20e-1)" "unprognostic (1.25e-2)" "unprognostic (1.87e-2)" "unprognostic (8.47e-2)" "unprognostic (3.95e-2)" "unprognostic (2.75e-1)" "unprognostic (1.74e-1)" "unprognostic (9.75e-2)" 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 35.9 0.0 0.0 0.0 0.5 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.5 3.7 3.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.7 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.7 2.3 0.0 0.4 0.0 0.1 0.2 3.2 0.0 0.0 1.7 2.5 3.2 0.9 0.0 3.4 0.0 3.9 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 3.8 0.0 0.0 0.0 0.2 7.4 0.3 0.0 0.0 1.9 0.0 2.9 0.0 0.0 0.1 2.7 0.0 0.3 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 TBX22 "CLPA, CPX" ENSG00000122145 "T-box transcription factor 22" Q9Y458 X 80014753-80031774 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "testis: 11.1;thyroid gland: 4.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HDLM-2: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (6.58e-2)" "unprognostic (6.31e-2)" "unprognostic (1.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBX3 "TBX3-ISO, UMS, XHL" ENSG00000135111 "T-box transcription factor 3" O15119 12 114670255-114684175 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 178.4" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 613.9" "Cancer enhanced" "Detected in all" "prostate cancer: 49.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 103.0;BJ hTERT+: 97.3;RT4: 129.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005799, HPA075876" Supported Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA005799: AB_1857817, HPA075876: " "unprognostic (3.27e-1)" "unprognostic (2.64e-1)" "unprognostic (2.84e-1)" "unprognostic (1.11e-1)" "unprognostic (3.40e-2)" "unprognostic (5.97e-3)" "unprognostic (1.56e-1)" "unprognostic (2.99e-2)" "unprognostic (9.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (3.06e-1)" "unprognostic (3.64e-3)" "unprognostic (1.09e-3)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "prognostic favorable (3.28e-4)" 13.3 178.4 5.1 2.5 4.7 0.0 34.1 3.9 5.7 37.5 2.9 7.4 37.6 32.8 44.6 2.8 24.0 4.5 13.2 3.8 14.9 12.9 31.3 32.8 1.4 4.6 4.4 44.2 2.9 1.0 12.9 41.3 4.8 80.4 3.7 1.8 18.9 53.2 10.4 14.9 30.3 10.0 3.8 7.0 6.0 1.3 6.6 1.3 50.0 16.5 1.7 53.9 34.2 3.7 2.4 18.2 0.0 0.0 26.1 35.6 40.1 103.0 97.3 39.0 38.3 16.3 4.4 0.0 1.6 18.0 2.4 4.7 8.4 3.6 47.7 0.0 12.3 0.0 4.8 48.1 8.4 0.0 0.0 16.0 2.4 13.1 26.8 0.0 0.5 0.0 3.8 0.0 3.4 1.6 0.0 0.5 0.2 53.0 5.4 0.0 0.0 2.6 0.0 129.3 6.6 19.4 14.6 6.6 3.6 44.6 5.1 0.2 0.0 11.9 7.7 6.8 33.9 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.7 3.9 5.7 3.8 14.9 4.6 4.4 4.8 3.8 6.6 3.7 48.9 0.0 1.9 0.3 1.8 9.8 85.2 5.8 7.4 14.3 110.3 80.5 12.5 0.0 1.1 35.0 4.2 60.7 0.7 12.0 0.0 0.6 1.5 3.3 144.7 38.6 4.9 0.0 0.0 0.0 7.0 41.3 5.1 3.8 0.0 3.9 1.1 40.2 6.1 1.7 0.0 23.9 4.1 0.9 4.6 2.8 5.3 2.9 3.6 14.0 0.0 1.9 0.0 0.0 0.0 0.3 22.4 6.0 0.0 72.4 37.9 0.1 0.4 2.0 39.5 27.2 58.2 0.1 3.8 3.2 9.8 613.9 2.0 112.0 12.1 69.1 TBX4 ENSG00000121075 "T-box transcription factor 4" P57082 17 61452404-61485110 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 32.3;placenta: 21.0;prostate: 9.0" "Group enriched" "Detected in some" 8 "Early spermatids: 6.2;Late spermatids: 14.6" "Cancer enhanced" "Detected in some" "lung cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 2.9;Hep G2: 1.2;OE19: 1.2;THP-1: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB032413, HPA044457" Uncertain Approved Vesicles NA NA "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB032413: AB_2200705, HPA044457: AB_2678948" "unprognostic (1.03e-2)" "unprognostic (2.05e-2)" "unprognostic (1.43e-1)" "unprognostic (1.63e-3)" "unprognostic (6.07e-2)" "unprognostic (3.80e-2)" "unprognostic (1.25e-2)" "unprognostic (4.14e-2)" "unprognostic (7.77e-3)" "unprognostic (7.41e-2)" "unprognostic (6.83e-2)" "unprognostic (1.38e-1)" "unprognostic (1.46e-8)" "unprognostic (1.92e-1)" "unprognostic (4.41e-2)" "unprognostic (6.15e-2)" "unprognostic (5.39e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.0 0.1 0.0 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 32.3 0.1 0.1 0.1 0.0 0.3 0.0 0.0 21.0 0.1 9.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 7.2 0.4 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 2.9 0.3 0.2 0.2 1.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 1.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.3 0.1 0.0 5.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBX5 HOS ENSG00000089225 "T-box transcription factor 5" Q99593 12 114353911-114408442 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 88.1;lung: 20.8;placenta: 28.7" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 104.7" "Cancer enhanced" "Detected in some" "lung cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 18.9;BJ hTERT+: 41.5;BJ hTERT+ SV40 Large T+: 9.2;BJ hTERT+ SV40 Large T+ RasG12V: 12.2;HAP1: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008786, HPA064683" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA008786: AB_10601720, HPA064683: AB_2685320" "unprognostic (3.09e-2)" "unprognostic (1.53e-1)" "unprognostic (3.79e-2)" "unprognostic (2.75e-1)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-7)" "unprognostic (2.29e-2)" "unprognostic (1.68e-2)" "unprognostic (7.34e-2)" "unprognostic (4.38e-3)" 3.4 0.0 0.1 0.0 0.0 0.0 4.4 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 88.1 0.9 0.0 0.0 0.0 20.8 0.6 0.3 0.1 0.0 0.0 1.3 0.0 28.7 0.3 3.4 0.0 0.3 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 5.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 18.9 41.5 9.2 12.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 16.3 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.9 0.0 0.3 0.1 0.3 0.0 0.0 0.2 2.9 0.0 0.6 1.6 0.0 0.1 0.0 0.0 0.0 4.5 0.1 0.1 104.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.1 0.0 0.0 0.0 2.1 0.3 0.0 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 7.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 TBX6 ENSG00000149922 "T-box transcription factor 6" O95947 16 30085793-30091924 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 8.4;Urothelial cells: 9.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "OE19: 4.1;RT4: 6.9;U-266/70: 6.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062498 Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA062498: AB_2732686" "unprognostic (2.47e-1)" "unprognostic (1.32e-3)" "unprognostic (5.62e-5)" "unprognostic (1.49e-1)" "unprognostic (4.76e-2)" "unprognostic (2.35e-2)" "unprognostic (3.35e-1)" "unprognostic (5.80e-2)" "unprognostic (1.84e-1)" "unprognostic (1.29e-1)" "unprognostic (1.77e-2)" "unprognostic (3.87e-1)" "unprognostic (2.76e-2)" "unprognostic (2.95e-1)" "unprognostic (4.21e-2)" "unprognostic (5.05e-3)" "unprognostic (4.26e-2)" 1.1 1.9 3.3 0.7 3.9 0.5 1.4 3.1 4.1 3.6 2.4 1.8 1.2 1.1 0.7 13.8 1.7 0.8 1.3 3.1 3.3 3.2 1.9 1.4 0.8 3.7 3.7 1.8 4.3 1.0 1.9 0.3 3.9 3.3 0.3 1.7 2.8 1.2 2.0 3.5 1.7 0.4 3.4 2.4 4.7 1.8 4.0 0.9 2.8 0.5 1.5 4.4 7.3 4.5 0.6 0.7 0.4 0.7 1.0 0.5 0.5 0.2 0.1 0.0 0.1 0.9 2.9 1.2 1.5 0.1 0.1 0.8 0.3 0.5 0.0 0.9 0.5 0.8 1.4 0.7 0.7 0.1 1.7 0.2 0.8 0.1 0.3 0.6 0.4 2.7 0.1 2.9 0.0 2.6 0.5 0.3 0.6 4.1 0.6 2.0 0.0 2.1 0.0 6.9 0.9 1.3 0.1 0.5 0.8 0.3 1.2 1.2 0.3 0.8 0.4 0.4 0.0 6.9 1.7 0.2 0.8 1.2 0.2 1.2 0.6 0.2 0.4 0.6 0.3 0.3 0.2 0.3 0.3 1.2 0.4 0.4 0.8 0.3 0.2 0.2 0.5 0.3 3.3 3.9 3.1 4.1 3.1 3.3 3.7 3.7 3.9 3.4 4.0 4.5 1.0 0.0 0.6 2.6 2.7 1.1 3.4 4.2 4.0 1.9 1.2 1.4 0.5 0.0 3.7 1.8 8.4 1.7 0.5 0.7 0.0 0.8 0.1 0.9 0.8 1.9 0.0 3.2 0.2 1.2 0.8 1.1 3.6 1.0 0.0 1.1 0.4 0.4 0.5 0.0 0.4 1.2 4.1 0.8 1.7 0.2 0.9 1.2 0.0 1.9 0.6 1.9 2.1 0.0 2.7 3.5 1.6 1.2 0.2 3.2 2.6 0.7 3.0 3.4 6.6 2.7 1.4 2.6 3.9 6.2 1.0 2.3 0.8 0.5 1.6 9.4 TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.8" "Group enriched" "Detected in many" 4 "granulocytes: 71.0;Hofbauer cells: 88.8;Kupffer cells: 193.6;Macrophages: 132.9;Microglial cells: 191.1;monocytes: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 14 "basophil: 324.3;classical monocyte: 322.4;eosinophil: 333.6;intermediate monocyte: 466.0;myeloid DC: 129.0;neutrophil: 271.1;non-classical monocyte: 423.1" "Group enriched" "Detected in all" 22 "dendritic cells: 129.0;granulocytes: 333.6;monocytes: 466.0" "Cell line enhanced" "Detected in many" "NB-4: 76.7;PC-3: 23.7;RPTEC TERT1: 21.0;U-937: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA031257, HPA031258, HPA031259" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 890000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" "HPA031257: AB_2673812, HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" 13.2 10.8 5.3 28.1 5.1 24.8 8.2 5.4 5.9 5.4 5.8 10.1 10.3 3.2 2.0 5.4 4.9 21.2 3.3 4.5 6.8 5.8 12.8 23.9 12.4 10.0 6.6 2.9 3.6 2.9 2.3 14.2 8.8 6.4 13.0 1.6 9.0 4.0 1.0 1.3 11.9 12.6 8.9 57.8 11.2 1.4 9.7 15.1 1.8 3.3 8.3 13.9 2.1 14.7 0.2 5.4 0.3 0.1 1.2 3.9 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 12.1 0.0 0.3 0.0 0.0 0.0 0.0 9.4 0.7 17.8 0.0 0.0 1.6 6.2 15.3 2.1 0.0 0.0 0.9 1.1 2.3 0.1 0.6 2.2 0.6 0.2 2.4 76.7 0.2 18.0 23.7 2.6 0.0 1.2 21.0 0.0 0.2 1.1 0.2 0.0 0.8 0.0 0.0 14.4 2.0 0.6 0.2 1.4 1.0 4.6 0.9 0.3 0.4 60.8 1.7 324.3 322.4 333.6 7.3 466.0 11.9 8.3 13.5 3.7 129.0 4.5 2.3 1.3 271.1 11.9 423.1 22.6 13.9 216.7 5.3 5.1 5.4 5.9 4.5 6.8 10.0 6.6 8.8 8.9 9.7 14.7 3.9 3.2 10.8 8.1 9.9 0.4 1.2 0.5 2.8 1.0 3.0 3.0 1.1 5.7 1.7 1.8 6.2 0.6 16.4 0.8 9.8 5.2 0.4 1.0 0.6 5.0 1.8 12.8 1.2 9.5 0.5 2.9 7.1 3.8 71.0 0.5 16.8 8.6 88.8 3.3 1.8 1.9 12.2 193.6 19.5 0.7 0.3 132.9 3.6 191.1 63.7 4.9 26.8 3.0 5.9 4.4 7.9 0.0 16.4 5.8 0.2 6.3 1.0 4.1 19.7 1.3 1.7 0.5 0.7 26.2 0.6 0.5 13.4 0.3 2.7 1.2 TBXT T ENSG00000164458 "T-box transcription factor T" O15178 6 166157656-166168700 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "parathyroid gland: 2.6;pituitary gland: 1.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "testis cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HeLa: 16.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA003322 Uncertain Supported Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 20: HeLa - Mitochondria" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA003322: AB_1080176" "unprognostic (5.68e-2)" "unprognostic (4.59e-2)" "unprognostic (6.21e-3)" "unprognostic (8.64e-3)" "unprognostic (9.34e-3)" 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 2.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 16.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TCF12 "bHLHb20, HEB, HsT17266, HTF4, p64" ENSG00000140262 "Transcription factor 12" Q99081 15 56918623-57299281 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 319.8;Microglial cells: 440.3;Oligodendrocyte precursor cells: 618.3;Oligodendrocytes: 1512.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004432, HPA065827" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear speckles" "CAB004432: AB_671267, HPA065827: AB_2685564" "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (8.26e-2)" "unprognostic (1.65e-1)" "unprognostic (2.07e-3)" "unprognostic (1.11e-1)" "unprognostic (6.63e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (7.83e-2)" "unprognostic (7.26e-3)" "unprognostic (5.57e-3)" "prognostic unfavorable (5.24e-5)" "unprognostic (2.03e-1)" "unprognostic (2.93e-1)" "unprognostic (3.15e-2)" "unprognostic (1.41e-1)" 26.1 21.5 29.2 23.4 45.5 21.2 29.5 37.1 34.0 75.6 17.2 26.7 28.4 47.9 24.3 26.6 46.3 37.1 21.8 30.5 32.6 28.4 25.0 28.9 26.0 43.1 39.3 43.3 19.7 44.0 11.5 33.4 38.3 32.0 30.3 29.4 23.3 28.3 20.5 21.3 28.4 44.1 34.5 25.0 25.5 27.4 35.5 133.0 29.0 26.6 28.1 31.2 22.4 55.7 25.4 50.8 204.5 70.6 90.0 79.0 36.1 52.2 89.6 45.1 58.9 34.0 20.3 35.5 42.3 78.3 33.4 30.4 84.3 37.3 56.7 47.5 29.8 71.7 52.7 40.4 62.4 46.1 36.1 69.4 66.2 42.9 112.2 60.1 81.0 163.0 81.7 46.8 61.8 9.5 109.4 25.0 57.5 26.4 20.9 143.2 234.9 33.9 61.5 53.1 43.6 121.2 58.7 21.0 52.0 65.3 33.6 93.9 63.2 75.5 57.5 32.2 78.2 24.6 49.7 59.4 40.8 86.3 90.9 27.4 13.8 11.3 17.4 17.9 14.3 13.4 14.0 16.5 20.0 14.7 16.2 14.8 1.5 16.8 26.3 8.4 23.0 14.1 29.2 45.5 37.1 34.0 30.5 32.6 43.1 39.3 38.3 34.5 35.5 55.7 35.5 54.5 19.6 212.9 37.7 26.6 20.6 14.2 44.9 13.8 24.0 20.4 19.3 14.3 21.2 16.5 35.5 10.4 20.6 17.0 13.7 16.0 23.7 25.9 148.0 38.2 9.0 34.9 117.7 11.8 15.5 42.3 52.0 33.3 23.4 26.9 25.7 18.2 27.5 13.5 319.8 16.8 10.2 38.1 30.0 19.9 25.7 33.0 14.2 440.3 17.4 29.0 18.6 618.3 1512.7 15.9 18.4 34.6 29.1 23.4 20.0 15.3 15.9 23.3 46.0 39.9 36.5 22.2 15.0 33.6 33.8 13.0 28.4 16.5 20.1 18.2 TCF4 "bHLHb19, E2-2, ITF2, SEF2-1B" ENSG00000196628 "Transcription factor 4" P15884 18 55222185-55664787 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.1" "Cell type enhanced" "Detected in many" "Adipocytes: 820.0;Endothelial cells: 574.5;Inhibitory neurons: 1177.6;Oligodendrocyte precursor cells: 719.8;Oligodendrocytes: 573.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 65.1" "Group enriched" "Detected in many" 14 "memory B-cell: 173.6;naive B-cell: 146.8;plasmacytoid DC: 559.8" "Group enriched" "Detected in many" 33 "B-cells: 173.6;dendritic cells: 559.8" "Cell line enhanced" "Detected in many" "HDLM-2: 140.4;SH-SY5Y: 157.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020722, HPA025958" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "CAB020722: , HPA025958: AB_1857849" "unprognostic (2.11e-1)" "unprognostic (9.10e-2)" "unprognostic (8.69e-2)" "unprognostic (7.89e-3)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (3.03e-2)" "unprognostic (8.64e-2)" "unprognostic (1.79e-2)" "unprognostic (3.29e-2)" "unprognostic (2.77e-1)" "unprognostic (8.44e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (1.99e-3)" "unprognostic (2.68e-2)" "unprognostic (2.76e-3)" "prognostic unfavorable (9.95e-4)" 20.3 9.6 3.7 12.8 12.5 9.5 11.6 65.1 26.5 28.5 0.0 7.4 5.1 23.0 2.1 9.7 13.4 17.4 17.5 29.8 0.0 4.4 4.4 15.5 14.7 5.5 1.0 25.9 5.8 8.0 6.5 28.9 3.9 6.6 7.9 14.0 6.8 10.2 6.1 6.4 5.0 24.1 2.2 13.1 6.0 15.4 2.4 9.8 13.3 16.7 14.7 13.1 7.3 14.4 0.1 4.1 36.8 11.4 8.5 14.4 0.1 18.4 40.6 13.2 17.2 23.1 3.6 28.8 0.1 41.9 2.7 4.5 17.9 17.1 9.2 140.4 13.9 12.1 0.1 0.0 4.0 5.3 2.8 19.6 5.3 18.5 0.7 9.1 45.8 1.6 19.5 22.0 11.0 0.0 7.6 0.0 10.4 0.1 2.4 41.6 14.9 65.4 0.0 0.9 12.6 157.7 0.0 1.5 0.0 11.1 1.6 1.3 49.1 48.5 17.4 2.1 14.6 16.3 32.2 25.7 11.0 5.2 15.5 0.9 7.4 0.8 0.9 8.3 0.7 173.6 0.2 0.5 20.6 146.8 0.5 0.3 1.8 11.2 7.4 559.8 0.7 11.3 3.7 12.5 65.1 26.5 29.8 0.0 5.5 1.0 3.9 2.2 2.4 14.4 820.0 6.4 13.1 501.1 217.4 117.0 37.8 34.0 80.8 293.0 6.5 23.4 35.5 4.3 32.6 22.0 83.4 1.8 446.8 0.1 0.0 1.5 103.2 17.5 201.4 574.5 5.4 34.2 503.8 7.1 1.5 296.7 1.5 12.2 13.9 105.7 316.3 6.6 39.6 25.2 1177.6 0.3 26.4 112.4 129.2 116.3 205.3 80.4 64.0 474.1 32.7 372.8 13.4 719.8 573.6 2.1 0.1 182.1 131.7 20.8 0.0 2.3 25.9 54.7 236.7 304.5 221.0 8.7 14.5 47.5 84.4 2.6 15.1 164.8 0.2 17.8 TCIRG1 "a3, Atp6i, ATP6N1C, ATP6V0A3, OC-116, OC116, TIRC7" ENSG00000110719 "T cell immune regulator 1, ATPase H+ transporting V0 subunit a3" Q13488 11 68039025-68050895 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 289.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 135.5;Kupffer cells: 115.2;Macrophages: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 131.9;RPMI-8226: 138.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038742 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria "HPA038742: AB_10795138" "unprognostic (5.35e-2)" "unprognostic (5.01e-2)" "unprognostic (1.81e-2)" "unprognostic (1.50e-2)" "unprognostic (6.98e-3)" "unprognostic (1.25e-1)" "unprognostic (5.07e-2)" "unprognostic (6.43e-2)" "unprognostic (7.03e-2)" "unprognostic (2.47e-2)" "unprognostic (1.36e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.50e-11)" "unprognostic (2.48e-3)" "unprognostic (7.88e-3)" "unprognostic (2.50e-1)" "prognostic favorable (9.45e-6)" 56.8 112.5 7.1 46.1 7.1 97.7 47.2 9.2 14.5 85.1 11.4 66.6 44.2 58.0 18.6 45.3 61.4 11.7 27.9 6.6 7.2 35.5 61.7 113.9 30.9 10.9 9.3 49.1 289.2 4.4 20.3 14.1 12.0 72.2 8.0 0.3 57.9 16.1 10.5 25.9 87.0 12.1 9.1 194.8 59.2 6.7 18.1 12.1 52.5 3.9 13.4 56.1 60.7 10.8 31.8 57.2 0.8 0.2 25.1 19.7 39.0 61.5 29.4 17.2 16.3 1.3 92.0 2.7 32.9 21.9 26.2 39.0 3.7 23.5 3.6 82.1 1.9 22.0 80.6 18.9 23.4 16.3 131.9 22.8 13.5 21.2 1.4 0.0 11.8 1.2 11.6 8.4 5.7 10.7 0.8 97.8 3.5 44.6 14.4 26.8 0.9 138.6 16.2 17.6 3.0 0.7 26.0 33.4 16.8 6.1 36.3 41.1 42.3 33.2 25.9 93.3 11.4 1.3 1.2 4.8 74.0 26.7 16.2 21.7 65.5 72.8 15.7 109.0 12.7 11.3 11.7 16.9 49.0 7.5 6.6 7.2 150.0 32.1 144.3 33.8 12.1 47.8 7.1 7.1 9.2 14.5 6.6 7.2 10.9 9.3 12.0 9.1 18.1 10.8 40.6 28.9 59.8 0.3 37.1 6.2 13.2 36.2 7.4 0.7 14.9 8.9 1.6 18.6 57.1 7.3 0.0 21.7 60.6 74.2 0.0 30.4 0.4 13.3 16.7 22.1 23.9 15.2 0.3 67.0 54.1 24.9 135.5 21.5 50.0 29.5 21.0 17.8 105.1 0.0 0.6 32.4 18.3 115.2 22.8 0.6 5.9 132.3 5.4 8.4 74.9 0.7 45.3 0.5 0.1 51.8 85.4 13.2 59.1 10.6 45.5 2.0 47.9 1.0 39.5 7.7 26.0 0.1 2.9 10.4 5.3 26.5 46.5 9.0 36.2 19.0 TCTN1 "FLJ21127, JBTS13, TECT1" ENSG00000204852 "Tectonic family member 1" Q2MV58 12 110614027-110663431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 98.9;Respiratory ciliated cells: 203.7;Spermatocytes: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039687, HPA040036" Approved Approved "Nucleoplasm,Vesicles,Actin filaments,Microtubules" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "Nucleoplasm, Vesicles, Microtubules" "HPA039687: AB_10795293, HPA040036: AB_10794759" "unprognostic (2.54e-1)" "unprognostic (7.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (1.13e-5)" "unprognostic (2.89e-2)" "unprognostic (6.53e-2)" "unprognostic (2.11e-1)" "unprognostic (3.05e-2)" "unprognostic (6.02e-2)" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (9.60e-2)" "unprognostic (9.97e-2)" "unprognostic (2.15e-2)" "unprognostic (8.41e-2)" "unprognostic (1.24e-1)" "unprognostic (4.27e-2)" 8.8 14.0 5.6 2.0 5.3 1.0 8.4 9.3 7.5 10.1 18.2 7.1 1.5 9.0 10.7 4.5 15.3 5.6 17.0 5.7 4.5 19.0 9.1 8.3 2.5 4.5 5.0 12.8 10.8 15.2 26.2 4.0 4.4 10.0 0.9 3.0 9.5 6.1 10.3 5.3 4.0 3.6 3.6 4.6 6.9 21.1 5.2 1.3 17.6 1.9 0.8 7.7 7.0 7.0 11.6 11.7 6.7 17.6 24.9 18.0 4.3 6.3 16.2 5.9 4.4 1.2 2.7 2.0 6.9 18.6 7.2 6.1 4.7 4.6 5.0 4.7 8.7 0.3 4.1 3.6 8.6 1.2 1.3 14.8 7.8 7.7 7.9 34.7 3.3 3.0 7.4 2.5 9.7 9.4 0.9 2.2 4.1 3.5 16.7 2.4 2.9 14.6 16.8 1.8 5.5 11.7 13.1 1.6 5.3 5.5 22.7 16.0 4.0 8.2 2.4 3.5 6.0 4.2 2.6 2.6 11.1 1.3 9.3 0.0 2.0 0.0 0.8 3.6 2.2 4.9 1.5 2.5 3.4 9.1 2.2 1.6 6.4 1.0 1.9 4.3 0.5 2.0 5.6 5.3 9.3 7.5 5.7 4.5 4.5 5.0 4.4 3.6 5.2 7.0 6.5 3.2 18.8 25.5 24.0 13.8 28.4 38.4 18.2 10.7 22.8 19.3 13.0 24.3 26.0 16.5 31.3 30.9 5.8 1.0 9.8 24.3 82.7 98.9 29.0 11.5 18.0 1.3 15.0 4.7 8.5 30.5 8.2 9.8 3.8 27.1 9.3 6.9 11.8 3.3 12.1 4.8 32.6 3.8 12.4 18.7 17.1 7.0 23.2 7.5 1.7 30.5 0.0 12.5 9.3 4.2 2.4 28.6 9.6 20.0 0.4 42.5 203.7 34.1 6.6 16.2 18.3 96.9 30.1 8.5 11.2 18.3 4.2 38.1 4.7 16.6 TCTN2 "C12orf38, FLJ12975, JBTS24, MKS8, TECT2" ENSG00000168778 "Tectonic family member 2" Q96GX1 12 123671110-123708399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 27.6;Respiratory ciliated cells: 32.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039900 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus, Vesicles" "HPA039900: AB_10673366" "unprognostic (3.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-2)" "unprognostic (1.63e-3)" "unprognostic (1.32e-1)" "unprognostic (3.09e-3)" "unprognostic (3.14e-2)" "unprognostic (7.05e-2)" "unprognostic (1.09e-1)" "unprognostic (3.97e-3)" "unprognostic (2.23e-1)" "unprognostic (1.69e-1)" "unprognostic (2.79e-1)" "unprognostic (2.46e-1)" "unprognostic (7.86e-2)" "unprognostic (2.68e-1)" 5.3 4.4 5.5 2.6 6.4 1.9 7.2 5.8 5.3 10.0 30.4 5.7 2.1 11.0 11.0 3.4 28.5 6.4 4.8 4.9 9.5 10.0 1.4 8.3 3.3 8.4 11.5 14.7 6.9 14.1 16.3 4.6 6.5 9.6 4.0 17.6 9.1 8.6 1.7 8.3 3.8 6.0 7.1 4.1 5.4 11.1 8.7 2.5 12.4 2.1 3.0 5.2 6.7 4.1 14.9 15.1 10.7 15.6 15.0 16.5 13.1 5.4 10.9 11.5 8.7 7.9 14.5 0.5 9.2 8.9 10.0 19.6 6.2 4.9 11.2 2.5 7.6 1.2 10.6 7.2 5.0 3.7 4.8 8.0 8.8 16.3 4.8 34.9 15.7 5.1 7.1 0.3 7.1 7.9 4.5 7.4 6.8 5.9 9.1 4.0 10.8 1.5 13.7 11.1 6.5 8.3 18.2 6.0 8.4 11.0 25.5 5.6 9.8 16.0 8.2 14.7 7.1 4.3 8.9 1.4 20.9 0.4 9.7 1.7 0.2 1.2 1.9 0.6 2.7 1.9 2.2 2.0 0.4 2.1 2.4 2.4 0.3 0.8 0.5 2.5 1.4 0.2 5.5 6.4 5.8 5.3 4.9 9.5 8.4 11.5 6.5 7.1 8.7 4.1 2.7 3.2 5.3 6.5 1.8 4.1 2.3 2.6 1.2 4.4 4.8 2.3 3.8 5.7 3.9 7.3 12.5 2.8 2.1 1.2 0.0 2.9 6.1 27.6 5.0 1.7 1.2 2.5 10.4 2.1 3.0 4.6 2.6 4.3 3.8 5.0 2.9 0.4 1.3 0.0 14.4 1.8 2.0 0.3 1.2 2.8 2.5 1.0 5.4 2.8 1.4 4.6 1.0 2.5 1.3 2.0 0.8 4.9 1.1 1.4 0.2 1.9 32.1 14.5 0.0 6.0 2.7 11.5 10.9 0.6 2.3 1.1 2.4 2.3 3.0 1.0 TCTN3 "C10orf61, DKFZP564D116, JBTS18, TECT3" ENSG00000119977 "Tectonic family member 3" Q6NUS6 10 95659823-95694143 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026987 Approved Approved Microtubules "Intracellular and membrane" NA NA 4400000 "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Microtubules "HPA026987: AB_10600911" "unprognostic (1.58e-1)" "unprognostic (1.54e-1)" "unprognostic (9.78e-2)" "prognostic favorable (5.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.50e-2)" "unprognostic (8.88e-3)" "unprognostic (1.08e-1)" "unprognostic (3.03e-2)" "unprognostic (9.25e-3)" "unprognostic (3.78e-3)" "unprognostic (7.29e-2)" "unprognostic (4.60e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (9.30e-3)" "unprognostic (1.59e-1)" 21.3 25.3 8.6 15.7 9.0 5.1 25.2 9.1 11.3 26.3 24.0 22.1 17.6 24.8 65.0 17.0 35.4 22.7 18.4 8.8 9.8 32.5 26.8 19.4 14.3 9.7 9.5 30.6 27.1 69.9 22.8 26.9 9.5 25.6 25.6 22.2 25.4 27.7 9.5 20.5 15.4 26.8 9.2 17.3 19.1 19.4 9.6 14.0 70.6 11.5 18.0 23.9 18.6 9.2 34.0 54.1 44.1 89.3 93.6 74.6 25.7 45.3 94.8 46.9 55.3 35.4 57.3 31.3 40.1 60.4 49.8 46.7 43.9 54.5 56.5 33.6 36.4 10.9 21.6 49.2 46.9 37.4 22.8 65.2 49.2 46.6 72.4 88.0 80.7 27.7 21.0 40.3 63.4 32.5 23.4 27.9 12.1 49.7 38.1 25.3 33.9 38.3 67.8 23.3 11.5 24.5 37.7 18.5 52.6 40.8 71.0 35.1 37.9 35.6 24.9 23.9 49.5 18.9 37.9 20.7 57.5 47.1 19.0 6.8 14.2 4.9 25.8 21.9 32.0 28.3 23.1 25.2 45.2 19.4 24.2 20.0 1.6 26.8 24.3 23.6 22.2 21.3 8.6 9.0 9.1 11.3 8.8 9.8 9.7 9.5 9.5 9.2 9.6 9.2 14.8 19.2 16.2 16.6 29.3 14.4 23.7 33.8 31.3 24.0 18.2 15.0 8.5 27.1 20.3 31.3 37.5 50.3 18.8 20.2 7.9 27.2 18.6 25.5 25.7 20.4 13.8 11.6 17.3 20.3 44.2 27.3 11.7 18.3 8.2 29.8 21.4 16.8 28.5 25.2 17.7 12.5 26.4 14.1 59.1 14.1 20.8 18.7 16.0 16.9 14.8 36.7 15.5 20.6 13.7 14.1 12.7 25.2 35.9 19.8 16.2 16.1 27.5 44.4 13.1 23.9 19.8 39.8 34.1 15.3 11.5 31.5 23.0 34.2 23.7 14.6 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TELO2 "hCLK2, KIAA0683, TEL2" ENSG00000100726 "Telomere maintenance 2" Q9Y4R8 16 1493344-1510457 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041348, HPA041473" Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Cytosol" "HPA041348: AB_10794514, HPA041473: AB_10795593" "unprognostic (1.27e-1)" "unprognostic (2.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (2.64e-1)" "unprognostic (1.91e-1)" "unprognostic (3.08e-2)" "unprognostic (2.94e-2)" "unprognostic (5.99e-3)" "unprognostic (1.47e-3)" "unprognostic (2.21e-1)" "unprognostic (6.75e-2)" "unprognostic (3.15e-3)" 12.3 13.2 7.3 7.6 7.2 11.3 13.4 8.8 11.0 15.2 5.7 12.6 8.9 14.1 1.1 14.4 15.1 3.7 13.2 6.9 6.4 13.6 14.8 11.6 8.1 10.2 7.6 14.4 12.2 4.3 12.5 4.8 7.6 15.8 1.4 1.8 11.4 4.8 17.0 14.4 14.4 2.4 6.4 18.6 11.9 10.0 7.6 5.8 13.2 4.9 3.1 13.6 13.9 8.3 19.7 28.8 8.8 16.8 3.4 3.6 33.9 30.5 5.7 14.4 10.4 37.0 18.3 28.8 25.8 4.9 7.1 20.5 6.3 11.6 2.7 16.9 55.1 16.5 36.7 21.8 5.7 21.0 23.9 7.0 4.3 13.4 2.8 4.9 8.6 24.6 43.2 10.1 5.8 66.3 24.9 56.1 28.2 6.9 23.9 73.5 12.3 29.4 5.4 18.3 36.8 20.6 26.5 24.8 9.8 3.3 23.2 25.3 13.8 31.2 21.7 30.5 25.8 18.2 12.6 53.3 9.9 29.3 26.7 0.0 5.7 2.9 4.1 7.2 3.9 4.1 2.9 3.4 6.9 6.0 3.1 2.5 0.5 3.4 10.7 4.3 2.7 4.7 7.3 7.2 8.8 11.0 6.9 6.4 10.2 7.6 7.6 6.4 7.6 8.3 15.8 0.0 2.7 18.9 15.2 6.9 7.8 10.4 10.2 13.7 12.7 9.8 1.6 11.5 6.3 9.2 12.5 25.5 9.1 19.4 5.9 8.2 2.0 8.4 11.0 9.6 2.4 10.8 5.3 7.2 20.2 11.4 15.8 9.2 2.5 21.2 8.9 12.3 19.6 18.5 6.4 17.2 8.2 11.8 7.0 1.9 7.5 8.6 8.8 10.3 13.3 17.3 8.2 8.5 7.0 6.9 5.5 14.7 8.7 8.8 13.7 6.3 5.1 20.1 13.1 9.9 11.4 9.8 8.2 10.3 6.5 22.0 9.6 19.0 23.5 5.1 TENM3 "KIAA1455, ODZ3, Ten-M3, TEN3" ENSG00000218336 "Teneurin transmembrane protein 3" Q9P273 4 182143987-182803024 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8;placenta: 13.1" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 635.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;BEWO: 63.3;HDLM-2: 90.0;T-47d: 86.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047043 Approved Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA047043: AB_2679914" "unprognostic (5.79e-2)" "unprognostic (3.01e-2)" "unprognostic (6.62e-2)" "unprognostic (4.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (8.28e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (2.31e-2)" "unprognostic (4.85e-2)" "unprognostic (2.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.47e-3)" "unprognostic (8.59e-2)" "unprognostic (1.07e-2)" "unprognostic (5.25e-4)" 5.0 5.1 12.0 1.6 18.4 0.0 2.0 0.0 12.3 1.5 0.0 4.3 0.8 2.9 0.6 0.8 1.0 2.4 1.4 21.8 8.1 0.9 0.3 0.8 0.8 2.8 7.3 3.8 1.2 5.1 4.5 13.1 0.0 3.7 0.8 3.9 0.6 3.6 2.1 0.4 0.9 2.3 0.8 2.2 0.7 2.1 7.4 2.8 6.1 4.3 1.2 1.6 1.4 2.0 0.3 2.6 66.3 0.4 13.2 23.5 63.3 7.8 2.7 6.9 6.1 33.9 17.6 0.0 0.9 52.6 28.6 3.3 16.0 3.4 6.8 90.0 26.7 0.0 0.0 0.0 1.3 0.0 0.0 31.2 1.2 21.5 15.0 15.4 9.6 0.0 0.0 0.4 10.6 2.3 0.1 0.1 21.4 0.0 2.8 0.0 17.1 0.2 0.1 0.1 27.2 25.2 4.0 0.5 0.1 35.8 86.0 3.4 21.2 53.7 38.2 0.2 39.6 0.0 0.0 0.0 28.2 0.0 40.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 18.4 0.0 12.3 21.8 8.1 2.8 7.3 0.0 0.8 7.4 2.0 0.1 0.0 0.0 23.8 0.0 0.4 0.2 0.7 1.8 50.8 1.6 2.2 3.9 0.0 0.1 3.7 4.2 112.7 0.0 0.0 1.9 0.1 12.4 0.1 4.5 0.7 5.3 0.0 115.6 1.8 54.6 4.1 0.0 0.6 0.0 7.7 1.1 0.7 10.4 5.0 635.6 0.0 0.0 0.0 0.7 3.2 8.4 0.0 1.8 8.4 0.0 10.6 0.0 12.1 24.4 0.4 0.0 2.6 0.0 0.4 0.0 0.3 0.0 3.1 0.0 4.8 3.2 3.8 7.2 1.8 0.0 133.4 0.1 4.1 0.1 0.1 TENT5A "C6orf37, FAM46A, FLJ20037" ENSG00000112773 "Terminal nucleotidyltransferase 5A" Q96IP4 6 81491439-81752774 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 225.9;salivary gland: 104.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 73.1;Endometrial stromal cells: 70.6;Extravillous trophoblasts: 115.4;Glandular and luminal cells: 176.7;Syncytiotrophoblasts: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 81.9;HeLa: 86.1;HL-60: 95.6;THP-1: 162.0;U-937: 72.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA051067, HPA067140" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA051067: , HPA067140: AB_2685788" "unprognostic (2.02e-1)" "unprognostic (3.02e-2)" "unprognostic (5.39e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "unprognostic (2.62e-3)" "unprognostic (5.93e-2)" "unprognostic (2.48e-2)" "unprognostic (2.53e-1)" "unprognostic (1.03e-1)" "unprognostic (1.40e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (7.18e-2)" "unprognostic (6.38e-2)" "unprognostic (9.25e-2)" "unprognostic (9.66e-2)" 13.5 21.3 4.3 7.9 4.6 225.9 12.2 9.0 5.8 21.3 9.9 17.2 16.4 10.2 19.7 4.4 12.0 32.3 21.7 4.0 14.0 6.4 35.9 9.1 5.2 7.8 7.1 23.6 8.3 9.4 17.4 18.7 6.1 9.9 16.9 8.7 104.4 24.8 2.1 18.7 22.2 11.1 5.0 9.9 37.8 3.7 6.7 2.9 8.8 5.1 4.3 16.6 8.8 5.3 3.5 5.0 3.3 0.2 67.9 29.8 6.2 27.0 19.2 15.7 23.5 51.0 2.6 0.3 1.0 81.9 10.0 2.9 2.4 4.2 11.5 0.0 6.2 0.1 86.1 8.0 21.2 95.6 7.1 13.2 2.4 12.3 2.1 51.2 2.0 0.8 1.4 0.0 10.6 14.7 0.0 67.2 0.9 29.2 3.8 0.0 28.8 0.1 2.1 6.2 3.3 4.4 12.1 5.2 8.3 9.9 1.2 162.0 4.5 17.9 3.8 7.6 7.6 0.4 0.3 0.3 25.3 72.7 7.8 37.3 29.9 46.3 11.5 29.6 6.8 18.2 4.3 5.7 24.2 21.0 8.1 8.0 13.8 16.9 47.3 8.5 5.6 14.0 4.3 4.6 9.0 5.8 4.0 14.0 7.8 7.1 6.1 5.0 6.7 5.3 22.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 40.8 44.2 0.0 0.0 0.0 5.5 0.0 39.9 43.1 0.0 3.9 30.5 0.0 73.1 70.6 2.9 0.0 0.0 0.0 23.4 115.4 32.7 0.0 176.7 0.0 40.9 0.0 0.0 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 9.8 0.0 0.0 0.0 0.0 26.7 0.0 0.0 5.9 0.0 0.0 3.6 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 162.0 9.4 12.6 0.0 0.0 TFAP2A "AP-2, AP2TF, TFAP2" ENSG00000137203 "Transcription factor AP-2 alpha" P05549 6 10393186-10419659 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 32.8;skin 1: 66.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 167.9;Cytotrophoblasts: 285.8;Extravillous trophoblasts: 260.6;Squamous epithelial cells: 147.7;Syncytiotrophoblasts: 700.1" "Cancer enhanced" "Detected in many" "melanoma: 45.6" "Group enriched" "Detected in many" 4 "cerebellum: 4.1;medulla oblongata: 3.0;midbrain: 1.3;pons: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 104.7;hTCEpi: 97.3;SuSa: 97.3" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;pons and medulla: 1.0" "Low region specificity" "Detected in many" "CAB000326, HPA056871" Enhanced Enhanced Nucleoplasm NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "CAB000326: AB_667767, HPA056871: AB_2683262" "unprognostic (5.97e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-2)" "unprognostic (1.27e-1)" "unprognostic (7.62e-5)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.45e-1)" "unprognostic (2.76e-2)" "unprognostic (3.33e-3)" "unprognostic (2.82e-1)" "unprognostic (1.40e-11)" "unprognostic (1.46e-2)" "unprognostic (2.14e-1)" "unprognostic (1.72e-4)" "unprognostic (2.25e-2)" 0.5 0.4 0.4 0.1 0.3 0.1 32.8 4.1 0.4 7.5 0.2 1.1 0.5 0.3 21.8 29.9 0.4 0.2 0.9 0.3 0.1 7.4 0.1 0.5 0.4 3.0 1.3 0.4 0.2 0.6 0.4 29.6 2.1 9.8 0.5 8.1 23.5 9.3 0.5 66.7 0.8 0.1 0.5 0.1 1.4 2.2 0.5 0.2 0.5 0.1 5.1 3.5 16.6 0.6 51.8 17.8 0.1 87.9 0.4 0.0 19.7 40.2 30.3 31.7 31.4 2.1 19.3 3.2 4.9 12.0 17.5 53.2 4.3 66.1 30.9 104.7 45.2 0.4 44.5 0.0 0.0 1.7 1.5 0.0 97.3 0.1 66.6 18.3 0.0 0.9 3.3 0.1 0.3 12.2 0.0 17.2 0.5 3.3 24.7 5.9 5.0 2.2 18.8 21.8 12.5 0.3 44.1 82.7 82.3 97.3 56.0 1.7 0.0 9.9 2.7 7.1 25.3 0.1 5.1 0.8 5.1 1.7 59.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 4.1 0.4 0.3 0.1 3.0 1.3 2.1 0.5 0.5 0.6 0.5 0.0 0.0 0.0 0.4 130.6 45.5 50.3 167.9 25.9 98.2 65.7 2.7 0.0 30.5 31.3 2.1 285.8 0.5 1.0 7.9 2.2 5.3 1.2 0.7 2.1 1.2 0.0 0.0 0.4 260.6 4.2 0.0 1.5 0.0 0.1 0.0 0.0 20.4 80.8 0.0 0.5 46.8 0.0 6.1 3.8 0.6 0.5 124.5 0.0 0.0 4.3 0.0 0.0 0.1 3.7 0.5 0.0 1.2 58.2 0.1 0.3 21.5 4.6 0.0 0.3 4.1 6.5 16.8 147.7 138.4 700.1 0.3 0.3 0.5 46.7 TFAP2B AP2-B ENSG00000008196 "Transcription factor AP-2 beta" Q92481 6 50818723-50847619 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 33.3;retina: 14.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 145.7;Bipolar cells: 76.4;Horizontal cells: 437.4;Melanocytes: 106.7" "Cancer enriched" "Detected in some" 8 "breast cancer: 12.1" "Group enriched" "Detected in many" 6 "cerebellum: 3.5;medulla oblongata: 3.9;midbrain: 9.0;pons: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 109.6;SH-SY5Y: 208.1" "Region enhanced" "Detected in many" "cerebellum: 10.0" "Low region specificity" "Detected in many" "HPA034683, HPA062942" Enhanced Approved Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA034683: AB_10670966, HPA062942: AB_2684909" "unprognostic (2.02e-1)" "unprognostic (2.29e-2)" "unprognostic (4.27e-2)" "unprognostic (5.88e-4)" "unprognostic (9.76e-2)" "unprognostic (2.10e-1)" "unprognostic (1.00e-1)" "unprognostic (4.57e-1)" "unprognostic (6.58e-6)" "unprognostic (1.13e-2)" "unprognostic (1.88e-1)" "unprognostic (7.17e-3)" 0.1 3.4 0.0 0.0 0.0 0.0 8.2 3.5 0.1 0.1 0.0 0.1 0.0 0.0 33.3 3.9 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 3.9 9.0 0.0 0.0 0.0 0.6 0.2 10.2 0.0 0.0 14.8 6.4 0.7 0.0 8.6 0.0 0.0 0.6 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 109.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 35.5 0.1 0.2 208.1 0.0 0.8 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.1 3.9 9.0 10.2 0.6 1.1 0.2 0.2 0.0 0.0 0.0 0.0 11.7 0.0 0.0 145.7 76.4 43.0 29.7 0.9 0.0 0.0 51.5 8.4 14.9 0.1 0.0 54.8 0.0 17.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 437.4 0.0 0.0 0.0 0.0 1.5 2.0 0.0 0.5 106.7 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.7 0.0 11.8 0.0 0.0 0.3 1.9 0.6 31.1 4.3 4.9 0.2 0.0 0.0 0.0 TGDS "SDR2E1, TDPGD" ENSG00000088451 "TDP-glucose 4,6-dehydratase" O95455 13 94574054-94596242 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 75.2;U-698: 97.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039927, HPA040857" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA No "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "Nucleoli, Cytosol" "HPA039927: AB_10795238, HPA040857: AB_10794867" "unprognostic (4.07e-2)" "unprognostic (3.56e-1)" "unprognostic (2.66e-2)" "unprognostic (2.76e-1)" "unprognostic (1.27e-1)" "unprognostic (2.25e-2)" "unprognostic (1.60e-1)" "unprognostic (2.87e-1)" "unprognostic (9.99e-2)" "unprognostic (1.96e-1)" "unprognostic (9.17e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (5.51e-2)" "unprognostic (1.13e-2)" "unprognostic (2.26e-1)" "unprognostic (1.71e-2)" "unprognostic (1.09e-1)" 10.4 9.4 5.3 8.2 5.5 6.0 12.4 5.6 8.2 10.4 6.3 8.0 10.2 8.0 11.8 6.9 9.2 6.8 5.4 4.9 5.6 10.9 30.0 7.1 12.9 5.6 5.4 12.1 10.0 8.1 8.4 10.1 5.9 7.9 9.5 6.9 7.7 7.6 4.1 7.5 9.2 6.7 5.6 9.2 9.1 6.0 5.3 14.1 13.3 4.3 11.0 9.1 6.4 6.6 16.7 7.2 11.6 10.6 17.2 13.5 14.1 15.3 14.9 14.2 13.4 18.9 15.9 26.0 14.8 10.9 8.8 10.4 20.1 11.9 14.9 20.3 7.7 20.7 8.1 18.1 21.0 75.2 13.8 14.9 9.5 8.0 22.8 11.1 13.2 18.9 21.3 8.9 13.3 10.8 20.6 38.4 15.2 26.8 8.3 17.1 11.4 15.9 18.3 7.4 15.9 8.9 11.6 24.2 43.5 19.1 10.2 39.8 12.2 5.6 14.5 8.6 12.6 20.0 11.4 97.5 14.9 26.5 15.5 14.7 5.5 10.8 9.6 6.6 14.9 9.5 11.6 10.7 8.7 7.1 16.8 12.5 1.6 12.1 8.3 7.6 13.8 6.9 5.3 5.5 5.6 8.2 4.9 5.6 5.6 5.4 5.9 5.6 5.3 6.6 7.4 12.8 6.8 8.1 12.8 2.4 9.2 15.9 6.8 4.3 7.8 7.9 5.2 8.6 11.9 7.3 2.1 15.7 12.5 5.8 9.8 11.9 1.2 10.4 8.9 7.0 5.4 3.4 7.7 9.1 17.7 12.9 6.1 6.0 11.4 7.7 7.9 21.4 11.2 1.7 6.7 7.7 8.2 8.8 7.2 1.0 14.3 7.5 8.8 8.4 11.1 7.0 7.2 12.1 10.4 8.9 6.6 8.2 10.7 10.9 10.0 17.6 15.9 4.7 26.3 6.7 8.1 11.9 12.3 8.5 3.7 10.4 11.0 9.2 9.1 9.7 TGFB1 "CED, DPD1, TGFB, TGFbeta" ENSG00000105329 "Transforming growth factor beta 1" 19 41301587-41353922 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 438.3;Extravillous trophoblasts: 452.1;Macrophages: 188.8;NK-cells: 223.5;T-cells: 221.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000361, HPA073356" Approved Approved "Golgi apparatus,Cytosol" "Secreted to blood" NA NA 1290000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" Cytosol "CAB000361: AB_2201910, HPA073356: " "unprognostic (1.49e-2)" "unprognostic (5.43e-3)" "unprognostic (3.29e-2)" "unprognostic (4.90e-2)" "unprognostic (3.75e-3)" "prognostic unfavorable (3.38e-4)" "unprognostic (8.51e-3)" "unprognostic (5.63e-3)" "unprognostic (2.47e-2)" "unprognostic (5.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.88e-1)" "prognostic unfavorable (1.19e-8)" "unprognostic (1.65e-3)" "unprognostic (2.79e-2)" "unprognostic (6.39e-2)" "unprognostic (4.86e-3)" 39.8 28.6 10.8 39.7 10.7 82.9 25.4 11.8 9.4 53.2 9.5 31.0 14.4 45.9 7.4 52.2 27.7 18.1 35.8 9.5 15.5 35.8 14.7 63.4 34.0 24.5 14.9 17.4 14.3 11.5 18.0 32.1 17.6 31.6 8.4 0.6 21.2 19.8 8.1 29.3 37.8 21.8 18.4 88.9 20.1 8.1 19.4 16.7 20.2 8.3 25.7 44.1 45.3 17.7 57.7 87.6 3.4 0.3 41.7 35.3 10.0 81.9 64.4 25.2 15.4 40.4 30.1 57.0 88.6 110.5 26.8 30.1 17.8 54.6 11.1 76.6 17.9 199.0 18.0 50.4 47.7 54.9 119.6 45.0 17.5 50.5 32.7 138.7 135.2 21.1 108.0 116.8 27.9 42.1 43.1 79.6 9.4 12.0 52.7 44.4 13.1 85.4 46.8 20.3 0.3 6.5 23.9 0.1 15.1 32.5 1.9 36.3 170.3 96.4 77.2 20.7 91.2 74.4 31.7 36.3 90.3 106.4 16.4 1.1 0.8 3.9 0.7 1.2 0.6 0.2 0.3 0.4 0.5 0.3 0.2 0.3 2.4 0.3 0.8 0.9 0.3 0.9 10.8 10.7 11.8 9.4 9.5 15.5 24.5 14.9 17.6 18.4 19.4 17.7 55.0 0.0 0.0 3.3 120.6 44.4 36.5 64.8 38.7 0.2 14.4 9.7 2.3 4.3 17.2 16.5 0.0 5.4 438.3 1.4 0.0 12.8 1.0 5.7 18.2 63.1 0.0 28.0 1.6 17.1 452.1 34.3 14.3 5.0 64.9 20.0 71.4 2.7 141.2 0.0 2.1 1.4 22.4 136.1 158.6 1.8 12.2 188.8 23.2 30.0 105.8 0.3 223.5 0.0 0.6 45.1 16.4 18.0 156.5 32.9 0.4 9.0 9.7 0.7 39.5 13.9 78.6 3.1 8.0 40.3 18.9 55.7 221.9 4.1 0.8 31.1 TGFB2 ENSG00000092969 "Transforming growth factor beta 2" P61812 1 218345336-218444619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Astrocytes: 119.1;Muller glia cells: 87.1" "Cancer enhanced" "Detected in all" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 59.6;hTERT-RPE1: 155.6;U-2 OS: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006134 Approved Vesicles "Secreted to blood" NA Yes 4890000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA006134: " "unprognostic (7.24e-2)" "unprognostic (7.23e-2)" "unprognostic (6.32e-2)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.86e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (2.64e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (6.04e-2)" 1.5 1.2 8.2 1.1 11.6 0.1 4.0 9.2 14.9 7.1 7.1 2.4 0.6 6.5 4.5 1.8 3.9 2.0 6.4 11.5 11.1 1.4 0.6 7.8 0.6 18.5 12.7 4.6 1.8 1.1 2.1 12.9 10.7 17.0 0.9 10.5 8.5 11.2 4.8 2.1 0.7 5.1 8.4 2.6 1.2 0.9 10.0 0.4 2.6 2.1 0.8 3.0 3.0 11.0 4.0 20.2 1.8 15.1 4.3 2.1 0.0 2.9 0.4 30.1 21.2 5.5 46.7 0.0 59.6 0.2 25.8 11.1 1.2 2.3 32.0 0.1 0.2 0.0 1.7 0.0 46.7 0.0 0.0 1.9 5.3 4.1 15.8 155.6 8.1 0.0 0.0 0.0 29.6 0.3 0.0 0.0 1.6 0.0 1.8 0.0 8.8 0.0 10.1 0.0 0.3 0.1 34.8 3.9 0.7 39.7 2.9 1.1 38.3 21.3 58.4 17.9 30.7 0.0 0.1 0.1 9.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 11.6 9.2 14.9 11.5 11.1 18.5 12.7 10.7 8.4 10.0 11.0 2.2 76.9 6.3 119.1 0.5 8.7 8.7 35.3 4.0 9.9 8.4 5.8 4.1 14.3 29.8 5.5 0.0 0.4 0.2 0.0 0.0 40.2 19.3 2.1 6.7 8.1 0.0 0.0 8.6 16.9 13.9 28.8 0.0 6.8 1.3 0.9 4.2 0.0 1.4 1.7 36.0 0.0 8.2 0.6 13.2 28.0 8.1 3.2 12.4 30.0 1.0 87.1 0.0 3.5 1.0 21.5 0.0 13.9 1.2 15.0 0.0 0.8 12.3 3.0 0.0 27.7 19.7 0.3 0.8 0.6 2.8 0.5 0.5 0.8 0.0 2.1 TGFB3 "ARVD, ARVD1" ENSG00000119699 "Transforming growth factor beta 3" P10600 14 75958097-75983011 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 28.8;Late spermatids: 48.9;Leydig cells: 27.1;Sertoli cells: 32.9;Smooth muscle cells: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "SK-BR-3: 104.6;T-47d: 75.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063582 Approved Vesicles "Secreted to blood" NA NA 44800 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA063582: AB_2685049" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (4.32e-3)" "unprognostic (1.29e-1)" "unprognostic (3.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (9.79e-2)" "unprognostic (2.83e-2)" "unprognostic (1.51e-2)" "unprognostic (5.63e-2)" "unprognostic (4.10e-1)" "prognostic unfavorable (4.01e-7)" "unprognostic (6.38e-3)" "unprognostic (1.10e-1)" "unprognostic (1.22e-2)" "unprognostic (3.27e-3)" 22.2 13.0 43.4 15.8 45.8 1.0 15.6 33.5 58.4 46.6 18.4 12.8 4.1 25.5 9.6 7.7 14.5 36.6 27.9 31.2 38.4 20.5 17.6 25.7 7.2 40.9 42.3 8.0 27.7 9.9 8.3 55.4 40.0 43.6 4.8 1.8 10.8 17.9 38.6 5.0 6.6 34.3 38.9 5.3 14.1 4.5 42.2 6.5 12.3 11.0 8.8 45.8 16.2 70.1 1.1 1.5 1.1 13.4 2.1 4.3 0.4 1.0 1.5 0.7 0.7 0.8 3.4 0.1 1.0 2.8 0.4 0.9 2.9 0.7 0.3 0.8 1.5 0.1 3.5 1.5 2.7 0.6 0.9 10.2 0.4 1.0 0.4 2.3 3.2 2.7 1.5 6.3 0.8 7.0 0.8 0.8 0.4 0.8 5.3 3.3 4.2 0.7 1.2 0.6 21.9 6.3 4.3 104.6 0.8 1.5 75.2 0.5 0.8 2.0 4.5 2.1 5.8 0.8 1.3 0.4 3.6 1.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.4 45.8 33.5 58.4 31.2 38.4 40.9 42.3 40.0 38.9 42.2 70.1 8.6 0.0 2.8 5.5 0.8 4.5 1.2 2.1 1.2 0.7 15.1 6.1 3.6 0.0 3.3 1.8 4.2 0.5 1.2 1.3 0.0 0.5 16.4 2.6 9.9 10.2 0.0 0.0 1.3 1.3 0.4 28.8 0.0 2.4 0.0 0.5 7.9 0.8 0.9 0.0 3.0 2.6 6.1 0.6 4.4 48.9 27.1 0.9 10.6 1.0 0.7 2.1 3.1 5.5 4.7 0.4 0.1 12.8 0.5 20.6 1.4 0.4 4.2 3.9 32.9 13.9 24.4 0.4 1.4 2.4 3.1 1.4 1.3 1.6 0.4 0.8 TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 128.4;Late spermatids: 101.7;Microglial cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 253.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "CAB002441: AB_564029, CAB031481: AB_2202455, HPA056473: AB_2683144" "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (2.80e-1)" "unprognostic (8.63e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-3)" "unprognostic (3.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.14e-2)" 15.9 9.9 9.8 18.2 9.3 33.7 15.4 13.2 8.9 19.4 11.8 18.8 11.7 20.6 8.8 15.0 8.5 21.7 8.2 6.8 11.3 22.6 14.8 16.3 13.8 18.4 14.5 13.0 8.3 8.5 7.6 48.8 20.0 17.1 13.4 4.7 8.3 16.8 8.7 6.2 9.3 33.0 18.0 16.5 18.4 18.3 17.5 11.2 11.2 13.2 13.6 22.5 8.4 27.9 13.7 19.5 115.5 36.1 26.2 19.3 17.4 44.1 47.8 40.7 44.9 19.9 9.3 29.7 13.4 34.6 32.1 30.4 39.6 34.1 54.0 77.1 12.3 43.9 20.7 17.8 43.2 27.2 102.8 40.2 35.4 62.8 29.5 25.2 7.4 10.9 62.4 12.1 55.4 20.3 4.0 31.0 24.7 12.2 11.5 11.0 253.1 12.5 9.9 3.8 31.1 36.2 34.3 150.2 46.4 47.3 28.1 36.6 13.6 29.8 25.5 129.3 27.3 12.1 13.4 20.0 62.5 45.9 26.2 16.2 2.4 9.5 7.8 1.6 6.7 1.6 3.3 5.8 2.0 1.2 3.2 6.2 4.9 4.3 2.0 1.4 2.4 2.2 9.8 9.3 13.2 8.9 6.8 11.3 18.4 14.5 20.0 18.0 17.5 27.9 13.5 6.4 8.8 18.9 18.9 23.6 7.4 19.9 44.3 8.0 18.9 11.7 7.6 4.3 12.8 60.7 0.0 23.0 37.3 5.0 0.0 18.8 128.4 6.4 22.7 17.6 9.6 7.4 14.2 31.2 6.7 36.0 9.2 9.3 29.9 19.5 6.4 12.7 49.4 0.0 8.6 7.3 8.2 32.4 52.5 101.7 9.6 39.7 35.6 116.2 24.3 3.1 35.0 45.8 21.1 33.8 4.2 13.5 11.9 18.4 3.6 13.8 5.0 2.0 32.9 21.8 20.9 11.0 12.7 25.6 16.2 19.4 25.4 7.6 8.3 11.5 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 230.0 56.1 16.5 73.8 12.9 29.4 145.7 13.8 19.3 90.0 30.6 96.0 44.2 69.1 18.2 44.9 69.6 91.9 95.2 10.6 13.4 67.9 59.1 148.0 70.1 17.6 16.5 26.6 52.0 59.0 16.9 81.6 16.7 44.1 54.1 2.1 49.2 60.8 31.1 39.1 77.7 107.2 17.3 111.1 63.4 7.8 21.5 49.7 91.8 62.2 60.7 98.0 55.1 17.2 16.6 100.2 5.3 0.1 313.6 472.3 15.9 83.9 116.1 28.5 27.7 22.9 86.6 2.2 298.2 117.2 32.2 33.3 4.0 125.4 42.0 7.0 8.9 10.1 10.7 104.5 128.5 14.9 76.6 430.0 93.6 126.3 114.4 117.0 296.0 10.9 1.8 0.0 381.7 1.3 16.2 10.5 2.2 75.7 39.8 14.1 36.4 2.1 113.5 40.5 0.1 5.6 24.9 6.1 22.0 6.6 0.0 14.0 418.6 134.7 33.2 61.4 32.0 2.8 0.3 12.5 80.1 16.1 55.8 9.0 3.0 11.5 3.4 3.1 3.3 4.5 4.8 3.3 2.6 6.4 16.6 7.3 13.1 1.9 8.0 6.6 0.7 3.8 16.5 12.9 13.8 19.3 10.6 13.4 17.6 16.5 16.7 17.3 21.5 17.2 391.5 144.2 99.7 0.7 77.0 37.3 18.9 23.5 39.9 5.1 23.7 24.1 84.5 50.1 39.5 27.6 0.0 6.8 85.3 10.5 3.9 13.1 2.5 28.3 57.5 236.4 8.4 20.4 0.4 15.8 5.1 129.2 39.3 30.8 29.8 0.7 478.0 55.5 30.4 0.0 1.0 12.4 22.4 147.0 58.0 3.8 32.9 67.9 30.2 170.5 47.5 0.2 56.7 6.0 2.4 37.6 12.1 47.4 37.5 8.6 13.6 7.2 14.7 1.2 32.9 60.8 53.4 0.3 1.2 8.0 30.5 3.7 68.2 1.7 14.5 10.8 TGIF1 "HPE4, TGIF" ENSG00000177426 "TGFB induced factor homeobox 1" Q15583 18 3411608-3459978 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 783.4;Basal respiratory cells: 419.8;Basal squamous epithelial cells: 483.2;Urothelial cells: 426.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA062160 Supported Nucleoplasm NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA062160: AB_2684701" "unprognostic (1.11e-2)" "unprognostic (5.20e-2)" "unprognostic (2.40e-1)" "unprognostic (1.97e-1)" "unprognostic (3.57e-3)" "unprognostic (3.10e-2)" "unprognostic (2.75e-1)" "unprognostic (4.34e-2)" "unprognostic (1.94e-2)" "unprognostic (1.96e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (9.60e-2)" "unprognostic (1.12e-2)" "unprognostic (9.81e-2)" "unprognostic (4.60e-1)" "unprognostic (7.07e-2)" "unprognostic (2.48e-3)" 51.2 40.1 21.7 43.3 20.8 41.5 57.6 22.4 25.7 68.9 30.2 51.5 31.6 51.2 133.7 46.7 74.7 65.3 29.8 20.2 29.3 74.0 61.5 47.6 26.4 29.8 27.3 67.3 46.9 26.9 22.0 63.8 25.7 54.6 65.7 8.0 56.5 56.1 34.4 60.2 37.8 37.4 27.5 35.5 49.1 25.9 25.7 40.0 66.7 26.9 27.0 112.1 40.0 28.4 33.6 148.5 92.7 29.3 90.0 121.7 235.7 63.1 236.6 49.9 62.1 61.0 142.6 1.9 20.9 49.8 165.7 33.7 35.0 73.8 61.6 13.9 16.8 4.3 73.2 110.5 178.8 47.6 38.3 89.5 291.7 89.7 233.7 131.3 104.4 22.3 36.0 0.4 95.6 65.8 31.1 58.8 240.8 119.0 34.8 32.8 43.2 10.3 198.1 156.7 27.1 26.5 166.2 123.0 92.5 151.3 28.1 43.7 49.6 77.5 65.6 92.7 41.1 5.0 0.6 15.7 78.5 18.6 98.2 65.4 42.8 7.6 62.9 16.6 67.8 46.5 52.5 61.9 35.1 32.2 37.1 43.5 19.8 21.5 16.7 3.3 32.1 36.3 21.7 20.8 22.4 25.7 20.2 29.3 29.8 27.3 25.7 27.5 25.7 28.4 41.0 35.3 40.2 8.1 106.5 359.6 783.4 419.8 483.2 0.0 114.1 72.1 5.6 100.1 128.3 123.2 0.0 161.6 60.1 30.0 49.0 117.1 41.5 167.2 58.5 66.6 46.4 25.7 2.7 75.0 220.9 102.8 79.0 240.2 68.0 71.5 29.3 35.7 71.8 1.7 0.6 99.4 136.3 44.9 221.1 9.7 28.6 126.8 76.5 7.5 71.9 6.7 11.3 4.0 1.7 106.0 53.0 15.4 15.1 308.1 24.9 113.1 93.3 0.1 32.9 90.9 86.6 7.9 15.4 223.9 257.1 150.4 103.7 8.0 91.8 426.2 TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 713.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Basal respiratory cells: 63.6;Club cells: 18.8;Distal tubular cells: 29.4;Squamous epithelial cells: 34.7" "Group enriched" "Detected in many" 4 "cervical cancer: 30.8;head and neck cancer: 78.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.5;HaCaT: 24.2;HeLa: 16.2;MCF7: 17.5;SK-BR-3: 21.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015159, HPA040171, HPA070372" Enhanced Approved "Vesicles,Plasma membrane" NA NA 530000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "CAB015159: AB_2202870, HPA040171: AB_2676869, HPA070372: " "unprognostic (2.95e-2)" "unprognostic (8.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.89e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.01e-2)" "unprognostic (6.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-7)" "unprognostic (7.11e-2)" "unprognostic (7.38e-2)" "unprognostic (2.22e-3)" "unprognostic (1.86e-2)" 25.7 1.3 0.6 0.9 0.8 0.7 2.2 3.7 2.0 78.7 0.8 1.4 0.8 1.0 1.6 713.5 4.4 0.6 5.1 0.5 0.6 2.5 1.7 5.3 1.5 1.5 0.9 3.0 3.2 0.2 3.3 1.2 1.4 4.1 0.9 1.7 89.7 4.4 1.1 73.2 1.9 0.5 0.4 2.6 1.8 2.9 0.9 1.3 2.7 0.3 40.4 1.3 144.2 0.9 1.1 2.0 1.1 1.0 0.0 0.8 17.5 0.4 0.2 1.0 1.6 1.2 1.7 1.0 2.3 1.3 0.3 24.2 2.8 2.0 0.6 2.0 3.3 1.4 16.2 5.7 0.8 0.9 1.5 1.5 9.3 0.5 2.0 0.5 0.7 3.4 1.0 1.0 0.7 17.5 0.7 1.9 0.3 1.1 2.2 1.1 0.1 1.1 0.6 2.1 1.2 1.6 0.2 21.7 0.1 1.4 1.5 1.1 0.8 1.1 4.8 2.0 0.9 1.5 1.8 0.3 0.4 2.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 3.7 2.0 0.5 0.6 1.5 0.9 1.4 0.4 0.9 0.9 0.2 12.8 1.1 2.0 0.0 0.3 4.6 63.6 4.0 0.9 1.1 0.8 0.8 5.7 18.8 0.0 0.0 1.4 0.3 0.2 29.4 2.0 0.1 0.3 0.2 0.2 0.0 0.0 1.5 0.9 0.8 3.9 0.0 0.6 4.5 0.7 0.0 0.2 0.4 0.0 1.7 0.1 6.1 0.6 0.3 0.0 0.6 0.4 0.0 1.0 0.4 0.2 0.0 1.0 1.0 2.6 0.0 0.4 0.1 7.4 0.1 0.2 2.1 0.6 0.0 0.1 1.0 0.0 0.6 34.7 1.8 1.2 0.6 1.2 0.3 6.2 TGM5 "TGMX, TGX" ENSG00000104055 "Transglutaminase 5" O43548 15 43232590-43266928 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 12.0;skin 1: 39.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.6;Club cells: 4.3;Early spermatids: 3.2;Late spermatids: 4.0;Suprabasal keratinocytes: 6.7;Urothelial cells: 12.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HEL: 16.6" "Region enriched" "Detected in single" 12 "cerebellum: 2.6" "Low region specificity" "Detected in many" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (3.17e-2)" "unprognostic (1.03e-2)" "unprognostic (5.92e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-2)" "unprognostic (1.94e-2)" "unprognostic (1.78e-1)" "unprognostic (7.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.77e-1)" "unprognostic (1.44e-15)" "unprognostic (1.94e-1)" "unprognostic (3.14e-1)" "unprognostic (7.22e-3)" "unprognostic (5.71e-2)" 0.8 0.0 0.0 0.0 0.0 0.2 1.7 0.2 0.0 3.9 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 4.3 1.2 0.3 39.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.3 0.5 7.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.3 0.0 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.2 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 2.6 1.5 0.0 0.0 1.0 0.5 0.2 0.0 4.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.2 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 4.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.2 0.8 6.7 1.9 0.0 0.0 0.0 12.1 THOC6 "fSAP35, MGC2655, WDR58" ENSG00000131652 "THO complex 6" Q86W42 16 3024027-3027755 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, mRNA transport, Transport" "Developmental protein, RNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 107.8;Extravillous trophoblasts: 121.1;Prostatic glandular cells: 109.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052953 Uncertain Supported "Nucleoplasm,Nuclear speckles" No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA052953: AB_2681997" "unprognostic (2.07e-2)" "unprognostic (4.13e-3)" "unprognostic (1.70e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-1)" "unprognostic (2.91e-1)" "unprognostic (7.82e-3)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "unprognostic (2.20e-2)" "unprognostic (5.15e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (3.59e-1)" "unprognostic (1.43e-1)" "unprognostic (6.17e-2)" "unprognostic (9.43e-2)" 17.0 16.9 8.6 16.1 9.1 23.5 15.3 9.6 11.2 16.1 9.7 17.9 18.8 20.3 6.0 19.3 13.9 10.5 15.8 8.6 9.2 22.2 21.3 17.5 20.8 11.6 9.1 11.6 12.9 10.8 17.4 18.2 11.8 21.1 10.1 2.1 15.2 12.2 25.9 24.9 19.2 12.5 9.2 22.7 15.6 10.4 10.2 19.6 15.7 8.4 16.1 17.1 16.5 9.5 37.3 59.6 42.0 45.0 21.1 23.9 74.4 11.3 25.7 25.7 37.8 39.6 42.8 70.0 36.0 18.9 19.1 49.9 46.3 35.6 14.0 62.3 59.9 38.0 58.6 58.7 35.9 56.2 80.0 24.3 42.6 31.4 76.9 32.4 24.1 39.7 56.1 36.5 12.8 87.0 32.0 103.3 76.2 21.4 25.3 84.7 31.6 82.4 27.1 18.6 86.4 41.0 31.8 49.9 21.7 18.1 35.9 60.0 20.1 26.8 61.1 30.6 41.3 26.3 24.3 85.5 7.0 38.1 27.3 2.4 61.3 13.6 35.2 62.2 36.2 37.8 32.6 34.7 88.6 43.2 37.1 39.1 4.4 38.8 35.7 74.3 38.0 45.4 8.6 9.1 9.6 11.2 8.6 9.2 11.6 9.1 11.8 9.2 10.2 9.5 11.0 19.2 7.4 1.6 24.7 68.2 84.9 59.0 30.7 3.7 22.1 20.8 3.3 14.3 18.9 18.4 2.1 107.8 23.3 23.2 35.2 33.1 5.4 17.9 19.0 17.9 25.8 30.3 1.9 23.5 121.1 24.6 15.3 25.8 12.0 15.6 6.4 10.3 51.8 3.3 1.7 32.3 44.7 19.4 37.3 3.2 14.9 23.4 24.9 2.8 39.6 3.2 15.5 0.5 4.2 21.5 28.0 12.0 19.7 109.4 32.1 32.0 8.7 2.4 6.6 23.4 31.9 5.3 23.3 23.3 44.9 77.2 20.4 20.9 42.2 46.8 TINF2 TIN2 ENSG00000092330 "TERF1 interacting nuclear factor 2" Q9BSI4 14 24239643-24242674 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 233.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059061, HPA069807" Enhanced "Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear bodies" "HPA059061: AB_2683895, HPA069807: AB_2686203" "prognostic favorable (4.96e-4)" "unprognostic (8.58e-2)" "unprognostic (1.53e-1)" "unprognostic (5.47e-2)" "unprognostic (3.20e-2)" "unprognostic (2.78e-2)" "unprognostic (4.75e-2)" "unprognostic (2.50e-1)" "unprognostic (4.70e-1)" "unprognostic (8.05e-2)" "unprognostic (1.05e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-3)" "unprognostic (2.04e-3)" "unprognostic (2.17e-1)" "unprognostic (4.78e-2)" "unprognostic (7.44e-2)" 47.2 76.4 17.6 17.3 19.1 20.1 44.0 18.9 23.6 42.2 17.7 40.7 11.5 43.7 21.0 63.2 36.1 12.8 39.4 17.6 18.4 48.5 33.5 44.1 22.7 19.5 18.6 32.2 44.6 233.5 31.9 14.2 19.5 37.9 15.7 12.8 37.6 16.2 45.2 40.8 38.4 19.4 18.8 55.8 41.8 16.3 18.7 29.2 40.7 16.1 26.6 40.9 41.4 20.0 18.4 16.4 23.2 12.2 25.1 18.5 11.8 18.3 23.1 26.3 24.5 7.1 20.0 26.7 10.3 26.1 19.0 17.5 13.2 16.5 16.5 34.1 6.7 16.8 15.1 28.5 21.6 17.9 23.1 20.5 26.0 21.1 20.0 24.5 28.9 25.0 6.7 33.1 21.5 20.0 27.0 8.8 5.4 19.3 20.1 21.9 14.8 19.5 23.7 25.8 14.2 13.2 19.1 18.0 17.0 15.3 12.9 11.4 23.3 12.2 14.9 21.0 14.6 25.2 19.5 15.1 14.8 9.9 18.6 124.6 47.8 113.7 59.7 51.1 48.1 58.7 46.5 56.2 41.1 65.1 48.3 48.4 60.2 63.5 49.3 34.9 61.5 75.8 17.6 19.1 18.9 23.6 17.6 18.4 19.5 18.6 19.5 18.8 18.7 20.0 34.6 16.0 23.0 6.2 54.5 16.8 63.8 35.7 26.7 23.0 18.4 17.7 13.5 15.7 29.3 18.4 8.4 31.8 51.1 19.2 35.2 35.1 8.1 12.8 15.7 31.4 13.1 15.8 4.1 47.2 26.5 28.1 16.8 18.7 40.5 10.0 27.8 16.5 35.5 15.2 4.1 16.3 32.6 30.1 19.7 10.7 23.6 29.9 21.4 7.5 43.3 41.8 72.1 3.5 7.5 40.5 23.8 29.7 31.5 38.9 22.0 25.4 9.5 18.8 26.3 25.8 29.9 24.3 26.2 27.4 25.1 42.3 46.5 29.4 15.6 53.0 TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873237-166104457 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.0;placenta: 6.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 115.1" "Cancer enhanced" "Detected in some" "renal cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 6.0;Karpas-707: 9.6;PC-3: 3.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "cerebellum: 45.8" HPA060767 Approved Vesicles "Secreted to extracellular matrix" NA NA 560000 "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA060767: AB_2684357" "unprognostic (2.17e-1)" "unprognostic (6.45e-4)" "unprognostic (8.60e-2)" "unprognostic (2.65e-5)" "unprognostic (9.85e-2)" "unprognostic (2.51e-4)" "unprognostic (3.37e-2)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-4)" "unprognostic (2.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.13e-3)" "unprognostic (7.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.21e-5)" 3.1 0.5 0.7 1.0 5.9 0.0 2.7 20.0 8.9 1.8 0.0 1.2 0.6 1.1 0.3 0.7 1.3 2.4 0.7 9.9 5.4 1.6 0.1 1.2 1.0 3.5 6.9 0.3 2.3 0.8 0.9 6.4 4.4 0.9 0.9 1.8 0.8 0.8 0.4 1.4 1.8 1.4 0.0 0.0 0.7 0.4 3.0 0.3 1.4 0.4 0.8 1.6 1.5 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.3 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 1.3 0.0 0.9 0.0 0.0 9.6 0.0 0.0 0.0 0.1 0.9 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.9 20.0 8.9 9.9 5.4 3.5 6.9 4.4 0.0 3.0 1.1 10.2 0.0 0.6 0.0 0.0 1.8 0.3 1.3 0.6 14.1 0.2 0.1 7.1 1.5 1.8 0.0 0.0 4.4 0.0 0.0 0.0 1.5 0.1 0.0 2.0 18.9 0.0 0.0 24.9 2.0 1.4 2.4 0.0 0.1 0.0 0.0 2.5 0.0 0.3 8.4 8.0 0.1 0.0 0.0 1.0 0.0 3.1 0.1 1.8 10.3 0.0 0.1 0.0 115.1 0.5 0.1 0.0 4.5 0.0 1.1 4.0 1.1 0.8 0.7 0.0 0.2 0.3 0.1 0.2 0.1 1.7 1.9 0.8 0.0 0.6 0.2 TMCO1 "HP10122, TMCC4" ENSG00000143183 "Transmembrane and coiled-coil domains 1" Q9UM00 1 165724293-165827755 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, Glaucoma, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054768, HPA078775" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "HPA054768: AB_2682597, HPA078775: " "unprognostic (1.22e-2)" "unprognostic (3.28e-3)" "unprognostic (2.36e-1)" "unprognostic (1.45e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (5.17e-7)" "prognostic unfavorable (3.21e-4)" "unprognostic (5.92e-2)" "unprognostic (4.16e-2)" "unprognostic (7.95e-3)" "unprognostic (1.78e-1)" "unprognostic (5.20e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.85e-1)" "unprognostic (1.94e-1)" "unprognostic (2.14e-2)" "unprognostic (9.80e-2)" 67.5 92.5 46.4 51.6 50.2 48.4 91.1 53.8 63.5 74.0 72.2 127.0 115.7 55.9 111.5 58.5 65.9 80.1 56.4 46.4 55.6 110.3 162.5 55.0 62.4 54.1 55.5 59.5 73.5 143.6 33.8 57.4 55.0 79.6 128.7 74.3 77.8 69.9 48.7 39.3 108.9 61.4 56.6 46.5 80.7 75.4 49.8 89.3 103.8 48.0 70.8 97.7 29.1 60.6 158.4 172.1 132.2 77.9 243.9 120.7 126.9 259.4 191.7 156.0 162.1 249.9 229.2 99.1 267.4 195.9 67.1 214.7 171.8 140.3 175.1 252.0 164.2 121.1 180.3 158.7 195.1 216.6 154.1 159.0 173.9 179.5 142.6 148.4 117.1 122.6 329.7 186.0 227.3 123.1 172.1 160.6 169.4 527.6 197.3 125.0 143.4 256.1 204.7 198.4 133.5 235.4 201.3 209.2 170.9 195.0 277.1 275.7 121.5 138.9 116.5 123.8 248.3 357.4 521.1 346.5 111.4 139.7 187.4 213.3 172.2 172.9 159.7 169.4 170.4 151.8 168.7 173.1 135.5 132.6 134.3 156.5 132.1 156.6 201.7 243.8 207.1 290.3 46.4 50.2 53.8 63.5 46.4 55.6 54.1 55.5 55.0 56.6 49.8 60.6 124.0 96.1 70.7 23.8 95.6 84.8 89.8 264.5 75.1 79.1 142.9 135.9 62.6 224.4 181.1 213.3 68.8 136.1 138.9 371.5 43.0 202.3 82.2 131.4 147.9 92.7 88.6 75.5 20.7 191.7 148.4 113.1 64.2 154.7 76.5 71.9 106.7 326.0 140.9 75.7 24.9 137.0 227.9 106.4 76.0 151.6 123.6 92.7 99.6 16.9 78.9 236.7 152.4 25.6 23.3 227.0 215.7 129.4 153.5 73.6 290.0 151.5 175.2 75.9 124.9 67.7 101.7 232.1 87.7 89.4 92.9 111.4 109.2 117.6 143.6 94.5 TMEM107 "JBTS29, MGC10744, MKS13" ENSG00000179029 "Transmembrane protein 107" Q6UX40 17 8172457-8176399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 110.8;Respiratory ciliated cells: 164.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052555, HPA059653" Approved Approved "Nucleoplasm,Plasma membrane,Midbody ring" Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Plasma membrane" "Midbody ring" "HPA052555: AB_2681870, HPA059653: AB_2684096" "unprognostic (2.87e-2)" "unprognostic (2.67e-1)" "unprognostic (2.85e-2)" "prognostic favorable (9.39e-5)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (5.70e-3)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (6.02e-3)" "unprognostic (1.83e-2)" "unprognostic (1.87e-1)" "unprognostic (2.66e-3)" "unprognostic (1.26e-1)" "unprognostic (4.99e-1)" "unprognostic (2.66e-1)" "unprognostic (1.49e-1)" 9.6 13.4 11.1 6.6 12.0 15.0 9.8 12.2 13.3 10.6 19.3 9.0 3.5 11.3 20.7 10.5 27.0 7.2 9.2 11.9 12.8 14.7 4.4 11.3 7.4 13.0 12.6 7.8 11.2 16.9 23.5 6.8 12.2 7.3 5.0 29.6 10.7 6.5 1.6 12.0 7.6 6.6 12.1 13.7 8.0 17.1 12.3 8.9 16.1 1.8 7.6 8.4 9.6 12.5 45.0 16.9 21.8 11.3 12.2 17.8 4.8 11.1 8.2 8.2 10.9 2.0 26.6 10.5 14.6 9.7 7.4 30.5 8.3 16.9 13.6 18.1 11.5 7.6 29.0 4.7 4.9 2.6 8.3 7.9 11.2 20.7 9.4 18.4 13.1 17.7 5.9 23.5 18.0 12.2 6.8 7.7 2.2 6.3 7.2 13.1 6.5 19.1 15.8 3.5 7.3 10.7 13.5 2.4 9.1 5.1 8.1 8.8 10.6 4.8 9.6 7.6 6.1 9.5 5.5 4.9 27.3 10.0 8.7 21.0 22.1 51.6 28.2 27.9 24.3 45.4 27.6 30.3 19.7 59.2 30.9 32.2 20.0 26.4 56.8 31.6 24.8 21.0 11.1 12.0 12.2 13.3 11.9 12.8 13.0 12.6 12.2 12.1 12.3 12.5 30.8 9.6 9.8 2.9 38.1 19.2 19.5 35.2 11.4 17.3 31.1 43.3 7.9 35.8 25.1 33.1 45.9 17.3 30.0 12.9 13.7 21.7 12.2 99.9 22.9 25.1 9.1 15.4 5.1 11.1 21.3 18.2 48.9 26.9 36.7 12.7 27.1 24.0 45.5 11.8 3.6 14.1 16.2 45.6 31.6 10.1 12.8 55.9 33.8 3.7 22.0 37.7 28.8 1.5 1.7 11.0 12.7 15.1 110.8 16.3 26.0 21.7 164.3 63.2 0.0 15.3 16.8 69.4 50.3 13.0 28.6 13.3 34.8 13.2 17.6 11.1 TMEM138 "HSPC196, JBTS16" ENSG00000149483 "Transmembrane protein 138" Q9NPI0 11 61362344-61369509 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 194.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042373 Approved Approved Microtubules NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" Microtubules "HPA042373: AB_10793880" "unprognostic (1.30e-1)" "unprognostic (4.69e-3)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (2.15e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (7.90e-4)" "unprognostic (1.06e-2)" "unprognostic (1.58e-1)" "unprognostic (1.86e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (2.28e-1)" "unprognostic (4.42e-2)" "unprognostic (3.49e-1)" "unprognostic (4.46e-1)" 13.8 40.6 8.4 11.5 8.5 18.1 14.3 10.3 9.7 16.3 10.0 13.4 10.8 17.5 25.9 10.8 17.3 11.6 9.1 8.7 9.1 17.9 22.2 15.3 18.0 9.0 11.0 23.7 13.9 18.4 12.6 14.9 8.6 17.1 18.7 50.7 11.1 13.8 6.8 18.6 15.9 18.6 9.0 18.4 13.5 12.5 8.9 14.0 13.5 8.5 22.8 17.8 13.3 9.5 16.3 35.5 14.0 20.3 48.9 20.1 16.5 24.9 30.7 36.2 32.8 17.7 24.6 14.0 21.0 29.7 56.5 30.2 26.0 31.0 39.8 18.0 14.4 10.1 28.7 21.0 35.0 21.8 26.3 32.4 47.7 60.5 39.4 13.5 31.4 16.7 29.8 23.0 60.1 45.4 17.3 21.6 22.8 28.2 34.5 11.9 10.3 30.4 32.3 39.6 14.9 11.1 31.7 30.4 34.2 12.8 47.3 19.0 18.7 45.2 18.7 31.5 24.7 24.0 24.6 13.6 23.7 26.5 24.0 41.7 26.0 26.5 23.1 26.6 25.3 26.1 21.7 22.3 15.9 24.1 24.0 21.4 5.3 27.8 18.2 28.0 30.2 24.1 8.4 8.5 10.3 9.7 8.7 9.1 9.0 11.0 8.6 9.0 8.9 9.5 12.6 16.0 23.2 16.0 23.1 19.9 16.1 49.8 25.0 28.9 15.7 17.1 4.2 4.3 26.2 20.2 81.3 54.8 27.3 13.9 15.6 17.1 21.7 22.0 16.6 18.7 9.6 22.1 12.5 16.0 39.9 20.5 9.2 7.0 37.3 17.8 13.6 16.3 45.7 15.2 12.1 11.6 16.2 15.6 10.7 7.6 31.7 35.6 37.4 3.7 25.5 25.9 36.0 10.1 8.1 18.6 11.5 28.6 18.1 22.1 26.7 20.8 59.6 194.1 0.0 15.3 14.3 24.9 16.2 16.3 20.5 27.5 23.3 56.9 14.3 12.9 TMEM216 "CORS2, HSPC244, JBTS2, MGC13379, MKS2" ENSG00000187049 "Transmembrane protein 216" Q9P0N5 11 61392360-61398863 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 192.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 84.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (7.75e-2)" "unprognostic (1.54e-1)" "unprognostic (6.20e-2)" "unprognostic (1.94e-1)" "unprognostic (1.06e-2)" "unprognostic (1.58e-1)" "unprognostic (9.02e-3)" "unprognostic (4.44e-2)" "unprognostic (1.97e-1)" "unprognostic (1.79e-1)" "unprognostic (1.90e-2)" "unprognostic (9.66e-2)" "unprognostic (2.59e-3)" "unprognostic (2.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.47e-2)" "unprognostic (8.03e-3)" 12.5 12.5 22.2 8.0 22.0 16.5 18.8 22.0 23.8 16.4 22.2 10.4 8.5 11.6 18.0 10.7 20.4 10.0 8.4 21.6 22.4 15.1 6.4 8.3 13.7 22.2 22.7 28.3 15.6 11.4 20.8 13.3 21.7 13.2 11.7 11.8 15.9 12.9 4.3 9.6 11.3 10.7 22.1 14.7 11.3 14.8 22.9 12.7 12.7 6.9 16.5 13.9 12.2 21.5 13.9 15.1 23.2 18.6 37.6 18.2 5.6 7.8 11.9 16.9 12.1 24.3 24.4 5.1 25.6 13.0 0.1 18.1 26.1 14.7 19.6 41.2 16.8 9.7 9.3 32.2 21.7 51.8 14.6 16.0 22.7 10.2 20.2 6.1 16.4 1.7 21.7 11.1 10.9 57.9 3.7 84.1 24.8 44.9 34.2 0.6 18.8 16.2 14.5 32.8 10.6 16.9 19.6 11.3 14.4 17.3 12.8 26.4 7.5 0.1 0.6 8.5 0.1 9.1 6.9 7.9 0.2 20.6 8.0 87.2 28.1 192.7 32.5 31.0 30.7 50.5 34.1 32.3 33.9 49.9 36.0 30.5 44.3 68.6 26.1 12.3 42.0 23.6 22.2 22.0 22.0 23.8 21.6 22.4 22.2 22.7 21.7 22.1 22.9 21.5 11.7 6.4 9.7 11.1 17.8 4.7 17.5 30.8 23.3 4.2 18.8 29.8 2.9 11.5 14.5 1.8 2.1 19.6 11.9 5.1 19.6 14.0 5.7 8.5 15.7 11.3 9.6 12.6 4.0 16.9 20.6 18.5 5.1 5.6 8.8 14.1 12.5 2.0 14.1 5.0 4.1 11.6 14.2 6.2 5.2 2.4 21.1 8.6 7.2 4.7 7.9 25.4 24.7 4.5 2.2 12.5 8.6 13.5 13.9 23.6 8.1 9.2 19.1 5.4 13.1 11.7 9.3 36.5 20.8 19.3 3.4 8.6 16.7 14.5 11.5 14.1 TMEM231 "ALYE870, FLJ22167, JBTS20, MKS11, PRO1886" ENSG00000205084 "Transmembrane protein 231" Q9H6L2 16 75536741-75556268 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "fallopian tube: 48.5" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 52.1;Endometrial ciliated cells: 121.2;Respiratory ciliated cells: 132.2;Rod photoreceptor cells: 33.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042081 Enhanced Approved Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA042081: AB_10795391" "unprognostic (4.29e-2)" "unprognostic (9.84e-2)" "unprognostic (8.07e-2)" "unprognostic (2.71e-3)" "unprognostic (1.03e-1)" "unprognostic (9.34e-2)" "unprognostic (2.90e-2)" "unprognostic (2.81e-1)" "unprognostic (2.92e-1)" "unprognostic (1.69e-2)" "unprognostic (3.34e-3)" "unprognostic (7.84e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" "unprognostic (1.66e-1)" "unprognostic (1.12e-1)" "unprognostic (1.28e-1)" 2.4 3.3 5.1 1.4 5.1 1.4 2.5 5.0 5.2 3.6 11.9 2.5 2.4 4.2 3.6 1.7 48.5 3.2 6.0 5.3 6.5 2.9 1.1 4.6 1.6 8.8 10.3 4.7 3.1 7.0 4.9 2.2 7.1 3.5 1.9 5.2 1.5 3.5 1.0 2.3 2.6 5.5 8.5 1.5 1.9 4.5 7.3 0.9 5.8 1.2 1.0 2.6 1.7 5.1 4.0 2.6 7.1 12.0 6.8 16.6 3.8 5.0 6.3 6.1 7.3 1.4 7.0 5.0 6.7 6.9 5.1 10.3 0.8 5.3 3.9 0.9 2.9 0.3 3.6 1.6 5.9 2.9 2.1 3.7 7.0 6.2 15.1 11.0 3.3 4.5 4.8 0.2 1.8 11.5 1.8 5.2 4.0 0.8 2.1 0.9 1.0 11.5 7.4 1.6 5.7 3.8 8.8 2.5 4.4 2.3 2.3 3.0 5.1 4.7 3.7 3.0 2.6 9.1 8.4 1.6 11.9 1.3 4.6 1.8 0.3 0.2 0.6 0.4 1.5 2.2 0.7 1.2 1.0 1.0 0.6 1.0 2.5 0.4 0.2 1.3 0.2 0.6 5.1 5.1 5.0 5.2 5.3 6.5 8.8 10.3 7.1 8.5 7.3 5.1 6.4 3.2 6.3 9.4 3.0 1.0 4.7 5.5 1.8 18.3 5.3 6.1 5.2 1.5 14.0 7.3 52.1 1.1 1.1 3.7 0.0 3.0 17.6 121.2 8.1 6.3 3.0 1.7 11.6 2.3 1.2 5.2 3.6 10.6 1.3 6.1 4.2 1.5 0.9 13.5 11.4 5.0 18.3 1.2 0.8 5.3 1.8 1.5 0.0 1.0 2.8 6.0 0.0 9.5 7.6 1.5 3.8 3.8 2.0 5.0 16.8 2.1 132.2 33.1 0.0 6.6 6.1 15.3 9.8 1.8 1.0 0.3 2.3 6.0 4.2 2.5 TMEM237 "ALS2CR4, JBTS14" ENSG00000155755 "Transmembrane protein 237" Q96Q45 2 201620184-201643570 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "retina: 89.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 81.7;Rod photoreceptor cells: 160.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052596, HPA054732" Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 79: Retina - Phototransduction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA052596: AB_2681879, HPA054732: AB_2682587" "unprognostic (1.70e-1)" "unprognostic (7.10e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (1.73e-1)" "unprognostic (4.06e-1)" "unprognostic (8.30e-6)" "unprognostic (4.15e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.96e-6)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" 4.1 15.1 6.3 1.7 6.5 2.3 11.0 7.1 7.8 5.0 6.0 3.0 0.8 6.0 4.6 6.0 5.8 4.1 7.7 6.8 6.7 5.4 1.9 5.1 2.3 6.9 6.9 8.4 1.9 5.0 3.0 5.2 7.2 7.8 3.7 89.3 5.1 4.8 7.7 18.5 1.8 5.8 7.1 1.4 2.2 3.0 6.4 7.0 4.6 9.2 3.1 4.1 3.4 6.8 3.7 7.2 32.3 16.4 7.8 10.1 3.1 22.6 9.9 14.7 28.4 5.9 5.3 3.7 6.9 21.9 12.7 6.8 5.6 24.4 27.1 6.9 20.6 10.7 21.4 19.4 15.1 10.4 2.1 9.0 5.0 20.4 5.1 24.8 25.5 23.4 7.8 13.0 29.8 5.2 29.7 16.3 32.7 1.9 23.8 43.9 30.8 7.6 12.2 9.7 33.7 47.4 21.4 8.4 12.6 20.3 12.5 18.7 6.8 26.8 7.3 8.6 9.5 6.0 14.9 11.4 22.7 9.7 17.0 0.0 0.0 0.0 1.0 1.1 0.9 0.7 1.0 1.6 1.3 0.1 1.1 1.4 0.0 0.9 0.7 0.3 1.8 0.5 6.3 6.5 7.1 7.8 6.8 6.7 6.9 6.9 7.2 7.1 6.4 6.8 6.8 6.4 9.6 12.4 1.6 71.2 81.7 46.7 50.7 33.3 17.1 41.4 20.2 2.8 18.9 18.4 41.7 21.0 3.1 0.6 13.7 11.1 8.9 16.3 10.9 11.6 4.8 8.6 16.5 7.6 26.8 25.8 3.1 7.7 5.1 19.9 10.4 2.7 9.4 32.0 15.3 4.5 18.3 2.2 12.2 7.0 21.8 2.9 12.4 4.7 5.7 38.5 0.0 14.1 10.8 6.5 1.9 21.4 3.0 36.9 0.7 3.9 19.8 160.3 6.6 33.2 20.6 33.3 22.0 30.0 45.3 15.1 4.2 39.8 5.3 29.2 TMEM38B "bA219P18.1, C9orf87, D4Ertd89e, FLJ10493, TRIC-B" ENSG00000095209 "Transmembrane protein 38B" Q9NVV0 9 105694541-105776629 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 77.4;tongue: 62.1" "Cell type enhanced" "Detected in many" "Early spermatids: 267.0;Late spermatids: 488.4;Spermatocytes: 157.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018465 Uncertain NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" "HPA018465: AB_1858116" "unprognostic (3.34e-1)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (2.68e-1)" "unprognostic (7.20e-2)" "unprognostic (1.51e-2)" "unprognostic (3.11e-3)" "unprognostic (1.88e-2)" "unprognostic (3.54e-2)" "unprognostic (5.82e-3)" "unprognostic (5.80e-2)" "prognostic favorable (7.96e-4)" "unprognostic (1.09e-1)" "unprognostic (2.09e-1)" "unprognostic (3.89e-3)" "unprognostic (9.98e-2)" 7.6 14.0 6.2 7.1 11.6 19.1 4.7 19.5 9.2 7.6 6.3 12.5 6.4 8.3 17.3 7.2 7.2 6.8 30.7 7.4 12.9 29.2 15.3 5.7 8.1 8.3 8.4 18.3 4.9 9.2 5.8 4.6 10.6 8.0 11.8 10.4 4.0 6.8 77.4 6.0 10.7 8.1 5.9 6.3 6.7 28.6 9.0 4.9 28.8 62.1 5.1 5.0 4.0 19.6 16.7 25.6 19.6 30.9 110.5 24.3 40.8 23.4 15.3 22.6 23.3 40.0 22.5 38.4 11.8 8.5 36.4 11.6 28.4 13.5 24.4 29.0 37.8 15.8 16.2 24.7 15.1 48.1 32.7 23.0 11.8 15.5 21.6 7.1 9.1 26.6 84.3 33.2 14.0 46.4 33.6 14.5 15.1 48.7 27.1 22.3 61.4 18.4 10.3 13.2 34.1 8.3 24.2 39.4 17.9 13.0 49.2 33.5 4.9 20.5 20.2 78.9 24.7 40.7 109.8 19.1 38.2 52.2 41.7 15.6 20.2 53.8 13.2 29.6 17.7 56.6 18.3 15.8 23.3 56.6 38.9 24.9 3.1 28.2 26.8 51.7 18.0 24.2 6.2 11.6 19.5 9.2 7.4 12.9 8.3 8.4 10.6 5.9 9.0 19.6 9.2 0.0 2.7 7.5 27.8 30.3 24.9 6.2 15.9 12.9 8.9 3.9 55.5 15.7 8.4 25.8 29.2 12.0 16.4 19.1 66.5 8.9 267.0 2.2 7.2 9.9 31.8 7.2 12.4 6.9 19.0 24.2 9.2 3.0 15.8 11.3 3.6 24.4 30.9 11.8 28.6 12.9 18.3 7.9 33.2 488.4 85.1 21.4 32.0 6.5 18.3 30.6 3.1 65.4 30.6 6.3 12.2 44.8 20.2 55.1 10.9 47.0 7.6 12.3 118.3 18.2 58.1 157.8 47.6 13.0 32.7 21.2 13.8 39.7 19.0 20.2 TMEM67 "JBTS6, MGC26979, MKS3, NPHP11" ENSG00000164953 "Transmembrane protein 67" Q5HYA8 8 93754844-93819234 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Deafness, Disease variant, Joubert syndrome, Meckel syndrome, Mental retardation, Nephronophthisis, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 66.7;Excitatory neurons: 59.8;Respiratory ciliated cells: 95.8;Rod photoreceptor cells: 83.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.57e-3)" "unprognostic (1.22e-1)" "unprognostic (2.45e-2)" "unprognostic (1.73e-1)" "unprognostic (5.07e-2)" "unprognostic (3.08e-1)" "unprognostic (2.25e-5)" "unprognostic (2.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.51e-1)" "unprognostic (4.43e-2)" "prognostic unfavorable (7.62e-4)" "unprognostic (8.41e-2)" "unprognostic (2.21e-1)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" 2.4 2.5 1.7 1.3 2.7 1.4 3.5 2.8 2.7 3.6 10.3 2.1 1.4 4.2 6.3 1.8 13.3 2.8 5.0 2.5 3.0 3.1 1.2 3.6 1.4 6.5 6.8 4.2 2.6 4.7 5.8 2.1 3.1 2.8 2.2 6.1 1.9 3.2 1.2 3.7 1.3 2.4 3.5 1.9 2.0 6.8 3.1 1.4 6.0 0.6 1.7 2.5 2.2 3.9 5.8 3.7 5.2 4.1 4.4 9.8 3.1 3.3 5.4 3.8 7.5 2.1 13.0 1.5 6.9 3.6 6.9 5.9 1.9 3.3 5.6 1.1 4.3 3.6 4.8 1.8 4.0 2.7 1.5 4.2 3.0 6.8 3.0 7.1 4.0 6.1 2.5 0.9 4.0 1.4 4.5 2.0 4.3 2.3 3.4 1.6 1.7 0.0 4.7 2.5 3.4 5.7 3.3 0.9 5.6 4.6 6.8 1.4 2.1 4.1 1.7 5.7 3.0 1.8 5.5 1.6 7.4 0.8 3.9 1.7 0.5 0.2 1.5 0.2 1.2 0.7 1.3 1.3 1.0 1.5 1.5 1.5 0.5 1.8 0.2 1.1 0.3 0.5 1.7 2.7 2.8 2.7 2.5 3.0 6.5 6.8 3.1 3.5 3.1 3.9 5.0 12.8 8.7 27.4 6.3 2.8 5.6 12.2 2.2 14.6 6.0 5.6 31.9 5.7 12.5 20.2 66.7 3.4 5.6 1.2 0.0 6.4 24.5 50.9 15.1 6.8 9.0 4.6 59.8 2.7 5.6 9.8 4.1 4.9 5.1 16.1 10.0 1.6 2.2 23.5 34.2 2.4 8.2 2.9 2.6 7.7 16.1 1.8 1.8 13.1 1.5 9.3 3.1 17.6 3.4 2.1 0.5 10.5 2.7 2.1 0.4 3.9 95.8 83.2 6.6 18.9 6.9 47.6 16.5 2.6 1.4 2.3 5.6 13.7 2.8 1.6 TMEM98 DKFZP564K1964 ENSG00000006042 "Transmembrane protein 98" Q9Y2Y6 17 32927910-32945106 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 250.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 4.1" "Lineage enriched" "Detected in single" 11 "dendritic cells: 4.1" "Cell line enhanced" "Detected in many" "CACO-2: 277.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040473, HPA053385" Uncertain Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA040473: AB_10794876, HPA053385: AB_2682134" "unprognostic (1.55e-2)" "unprognostic (5.15e-2)" "unprognostic (4.36e-3)" "unprognostic (7.20e-2)" "unprognostic (1.19e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.14e-4)" "prognostic favorable (7.10e-4)" "unprognostic (6.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.41e-1)" "unprognostic (9.18e-3)" "prognostic favorable (3.85e-4)" "unprognostic (5.16e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-1)" 56.3 50.6 48.9 17.3 84.1 4.7 44.5 75.3 64.1 68.6 161.9 90.0 102.5 100.4 74.2 27.9 96.5 93.9 44.3 51.2 56.9 36.5 27.5 58.1 5.7 72.8 77.4 191.9 88.5 53.7 23.9 28.2 69.7 80.7 96.3 15.7 50.1 23.9 5.3 24.6 118.4 62.3 51.9 19.6 101.6 20.7 75.0 4.4 47.7 14.6 7.7 50.7 42.6 109.3 7.4 27.2 115.5 0.2 154.7 138.0 1.1 114.2 153.2 59.2 126.5 277.6 8.1 1.6 1.7 144.0 2.1 0.9 74.2 30.1 34.5 24.7 92.0 4.6 0.1 124.5 71.5 0.3 1.7 116.3 29.7 74.7 12.1 31.6 154.8 40.7 78.1 0.3 162.9 0.2 0.1 0.7 77.0 83.1 42.0 0.2 108.4 0.5 13.6 49.0 9.8 158.3 2.7 0.0 89.8 72.6 36.5 0.2 128.2 83.8 78.1 1.0 0.2 9.2 3.8 0.1 42.9 0.1 46.2 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 4.1 0.0 0.1 48.9 84.1 75.3 64.1 51.2 56.9 72.8 77.4 69.7 51.9 75.0 109.3 7.6 41.7 24.8 6.2 0.6 25.1 76.1 111.5 27.3 1.4 32.4 104.5 14.1 72.9 61.0 46.0 0.0 8.1 0.7 109.2 5.9 81.0 18.2 14.7 48.5 7.8 97.9 2.7 0.6 66.4 7.3 127.2 40.8 12.1 3.8 87.8 29.6 13.0 5.7 0.0 0.3 145.7 40.7 0.6 15.9 14.9 120.5 2.0 44.4 1.9 0.0 106.3 0.0 3.0 173.0 88.2 97.9 151.6 0.2 68.1 250.9 37.2 54.6 4.8 65.7 22.1 55.5 40.7 27.7 17.1 12.6 7.1 2.4 132.6 166.6 68.6 TMTC3 "FLJ90492, SMILE" ENSG00000139324 "Transmembrane O-mannosyltransferase targeting cadherins 3" Q6ZXV5 12 88142296-88199887 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transferase "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038550 Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038550: AB_10672715" "unprognostic (1.05e-1)" "unprognostic (6.16e-2)" "unprognostic (1.50e-2)" "unprognostic (1.18e-2)" "unprognostic (1.90e-1)" "unprognostic (5.28e-2)" "unprognostic (3.62e-3)" "unprognostic (1.71e-2)" "unprognostic (1.46e-1)" "unprognostic (4.44e-1)" "unprognostic (8.07e-3)" "unprognostic (2.56e-2)" "unprognostic (2.28e-1)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" 5.9 4.4 3.6 3.8 3.8 1.7 6.7 5.8 4.7 5.6 2.1 4.5 5.4 6.4 5.2 9.1 3.9 5.7 3.8 3.9 4.6 8.1 9.0 5.2 2.9 3.4 3.9 5.3 3.2 6.2 2.8 10.2 4.1 7.4 4.7 7.9 3.8 6.3 1.7 12.5 4.4 9.2 3.2 3.9 3.8 4.1 3.6 4.0 6.3 4.3 4.5 6.8 4.7 4.1 13.2 14.0 12.6 11.9 28.8 25.4 22.5 28.1 26.6 15.8 16.9 20.3 9.2 4.1 5.0 25.8 9.6 28.9 13.5 22.4 26.5 2.4 10.2 4.0 9.5 9.3 15.0 4.3 2.5 21.7 12.0 30.5 12.0 16.2 24.9 3.4 8.9 1.4 17.8 7.9 3.0 5.5 9.7 5.0 7.3 2.6 27.4 4.1 13.7 21.3 10.7 10.6 22.8 16.1 7.3 13.3 25.9 4.3 26.4 21.8 12.0 19.4 13.7 4.5 6.3 4.7 6.8 5.0 16.5 7.4 1.3 2.3 1.8 1.1 2.2 2.3 2.0 1.4 0.9 1.8 2.4 2.0 1.3 1.2 1.6 0.9 1.7 0.7 3.6 3.8 5.8 4.7 3.9 4.6 3.4 3.9 4.1 3.2 3.6 4.1 15.9 12.8 8.2 19.6 6.9 34.2 24.4 29.1 24.5 12.5 11.4 8.1 11.1 5.7 20.0 7.3 27.1 29.6 3.5 6.7 3.9 14.5 26.8 23.7 22.2 16.9 3.6 9.5 51.6 10.8 18.2 23.8 8.6 21.9 9.5 12.4 15.7 19.2 8.2 13.5 46.8 5.9 75.3 5.9 6.0 18.2 20.2 3.7 8.8 20.6 2.8 8.3 2.1 28.1 42.4 12.4 4.9 19.5 4.6 18.0 7.3 13.9 34.9 23.4 19.7 17.1 22.3 12.0 8.7 32.6 40.5 17.8 5.2 14.1 7.1 14.4 TNFRSF11A "CD265, FEO, LOH18CR1, PDB2, RANK" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.5;salivary gland: 25.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.6;Intestinal goblet cells: 24.0;Paneth cells: 42.3;Proximal enterocytes: 25.5;Undifferentiated cells: 42.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 5.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 5.3" "Cell line enriched" "Detected in many" 6 "HDLM-2: 125.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 110000 "Cluster 48: NK-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" 1.8 1.1 0.8 5.7 1.6 0.4 4.1 0.1 1.9 1.4 0.3 17.1 30.5 0.9 0.3 2.8 0.9 7.6 0.6 2.0 1.1 0.4 0.6 1.0 1.2 0.7 1.1 0.4 1.7 0.9 6.8 3.2 0.2 1.3 17.6 0.2 25.4 2.7 0.3 2.7 18.6 1.7 0.7 0.8 5.5 0.9 1.2 1.0 1.2 0.1 1.9 1.6 1.6 2.1 3.2 2.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 1.6 0.4 0.6 0.0 3.5 0.4 1.4 2.2 8.3 0.9 0.2 125.9 5.4 0.0 1.3 1.7 0.0 0.5 1.3 0.2 0.4 0.8 3.1 4.2 3.1 0.3 0.0 0.0 0.0 1.1 0.0 0.1 5.9 7.0 19.3 0.4 0.0 0.6 1.5 1.5 20.4 0.7 0.6 3.0 0.1 0.8 1.3 0.4 2.0 0.0 0.1 0.1 0.0 1.2 0.0 0.1 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.3 0.6 0.0 0.8 1.6 0.1 1.9 2.0 1.1 0.7 1.1 0.2 0.7 1.2 2.1 0.4 0.0 2.2 0.0 0.4 1.3 3.8 1.1 0.6 0.6 4.5 3.3 1.3 8.6 2.3 0.0 0.0 0.1 3.3 35.6 0.0 8.3 0.3 3.2 0.5 5.3 10.8 0.0 4.0 7.5 0.6 0.7 11.7 6.2 0.0 2.0 7.1 0.3 15.5 3.3 0.2 24.0 0.0 17.0 2.4 0.4 0.6 7.7 1.8 8.4 19.7 0.0 3.1 0.5 0.4 14.7 42.3 0.0 0.5 2.8 25.5 0.0 3.8 0.2 0.0 0.5 0.4 0.8 1.9 1.7 2.3 0.1 0.7 0.0 42.2 4.4 TNFSF11 "CD254, ODF, OPGL, RANKL, TRANCE" ENSG00000120659 "TNF superfamily member 11" O14788 13 42562736-42608013 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Cytokine, Developmental protein, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 4.5;liver: 5.2;lymphoid tissue: 15.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 10.8;Breast myoepithelial cells: 5.1;Ductal cells: 6.2;Early spermatids: 8.0;Late spermatids: 15.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "NK-cell: 13.6" "Lineage enriched" "Detected in many" 7 "NK-cells: 13.6" "Cell line enhanced" "Detected in some" "HSkMC: 2.1;NTERA-2: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB009193, HPA045142" Enhanced "Secreted to blood" NA NA 17200 "Cluster 15: NK-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 35: Glandular cells - Unknown function" "CAB009193: , HPA045142: AB_2679231" "unprognostic (3.97e-4)" "unprognostic (1.40e-1)" "unprognostic (9.01e-3)" "unprognostic (3.81e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (7.09e-2)" "unprognostic (7.70e-2)" "unprognostic (2.29e-1)" "unprognostic (1.25e-3)" "unprognostic (1.00e-1)" "unprognostic (1.50e-1)" "unprognostic (3.94e-5)" "unprognostic (1.87e-1)" "unprognostic (9.67e-2)" "unprognostic (5.46e-2)" "unprognostic (7.74e-2)" 0.2 0.0 0.0 4.8 0.0 0.2 4.5 0.0 0.1 0.8 0.2 0.9 0.4 0.1 0.0 0.1 0.0 1.4 0.1 0.0 0.1 0.1 5.2 0.1 15.2 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.4 1.1 0.0 0.1 1.9 0.0 0.0 0.6 0.5 1.3 0.1 1.5 0.0 0.1 5.0 1.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.4 0.1 0.0 0.3 0.0 0.0 10.8 5.1 0.4 1.5 0.2 0.0 0.0 0.0 2.3 0.0 0.0 6.2 8.0 0.5 0.1 0.1 1.2 0.0 0.2 0.2 0.0 0.2 0.0 0.7 0.0 0.3 0.0 1.0 0.0 0.0 0.7 0.9 0.0 0.0 0.4 15.3 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.1 3.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 0.0 0.3 0.0 1.8 0.0 0.0 0.0 TNNI2 "AMCD2B, DA2B, FSSV" ENSG00000130598 "Troponin I2, fast skeletal type" P48788 11 1838981-1841680 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 25 "skeletal muscle: 7969.8;tongue: 2622.3" "Group enriched" "Detected in many" 6 "Extravillous trophoblasts: 449.4;Skeletal myocytes: 598.7" "Group enriched" "Detected in many" 10 "cervical cancer: 12.7;head and neck cancer: 33.6;pancreatic cancer: 12.9;urothelial cancer: 39.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 86.4" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "CAPAN-2: 35.7;hTCEpi: 101.2" "Region enriched" "Detected in single" 6 "olfactory bulb: 5.1" "Not detected" "Not detected" "CAB018697, HPA055938" Enhanced Approved "Plasma membrane,Intermediate filaments" NA NA 110000 "Cluster 52: Eosinophils - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Intermediate filaments" "CAB018697: AB_628400, HPA055938: AB_2682976" "unprognostic (2.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.29e-2)" "unprognostic (3.70e-1)" "unprognostic (1.85e-1)" "unprognostic (1.02e-2)" "unprognostic (9.99e-3)" "unprognostic (1.01e-1)" "unprognostic (1.73e-1)" "unprognostic (1.51e-1)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "unprognostic (1.23e-3)" "unprognostic (5.92e-3)" "unprognostic (5.62e-2)" "unprognostic (1.77e-1)" "unprognostic (2.79e-2)" 3.0 1.8 0.3 1.1 0.3 6.1 7.9 0.3 0.6 1.0 0.4 1.2 0.3 0.8 0.3 66.9 0.9 5.6 1.7 0.3 0.4 0.7 1.6 7.8 1.6 0.4 0.4 0.7 8.8 0.0 0.9 3.0 0.4 14.0 0.2 0.0 216.1 3.2 7969.8 55.2 2.7 0.2 0.4 5.8 1.1 0.7 0.5 1.9 2.8 2622.3 1.0 27.4 3.2 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.4 35.7 1.0 0.2 0.0 0.0 1.7 0.0 1.3 0.0 0.0 0.0 0.1 0.0 2.1 0.2 0.0 0.1 8.1 101.2 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 3.1 0.0 0.1 1.2 2.4 0.0 1.0 0.0 1.0 0.0 0.7 0.0 0.0 12.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 13.8 5.8 53.3 0.1 12.5 0.1 3.8 0.0 0.0 8.0 4.8 0.0 0.0 39.7 0.4 17.6 86.4 0.0 2.5 0.3 0.3 0.3 0.6 0.3 0.4 0.4 0.4 0.4 0.4 0.5 0.6 1.2 3.2 4.4 0.0 9.1 25.1 2.6 1.8 15.4 0.0 0.5 23.7 5.6 21.5 3.0 0.0 0.0 33.8 15.7 0.1 0.0 1.4 0.0 1.4 0.2 2.0 0.0 0.0 0.0 0.6 449.4 2.4 1.1 0.1 10.8 0.4 0.4 0.3 39.6 0.0 0.0 0.0 2.0 18.8 10.7 0.0 0.3 25.9 0.0 0.0 16.0 0.0 1.0 0.0 0.0 1.4 0.0 0.0 4.2 0.1 0.0 0.2 13.2 0.0 0.0 598.7 2.4 0.0 0.6 2.7 6.5 87.2 1.9 4.3 0.0 0.9 TNNT3 "AMCD2B, DA2B, DKFZp779M2348, FSSV" ENSG00000130595 "Troponin T3, fast skeletal type" P45378 11 1919703-1938706 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 43 "skeletal muscle: 13906.8;tongue: 4507.7" "Cell type enriched" "Detected in many" 4 "Skeletal myocytes: 542.6" "Group enriched" "Detected in many" 9 "head and neck cancer: 28.8;urothelial cancer: 19.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 17 "basophil: 5.3" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.3" "Cell line enriched" "Detected in some" 21 "HSkMC: 24.0" "Region enhanced" "Detected in some" "olfactory bulb: 5.1" "Low region specificity" "Detected in single" "CAB002451, HPA037810, HPA056909" Enhanced NA NA 470000 "Cluster 34: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "CAB002451: AB_564151, HPA037810: AB_10966217, HPA056909: AB_2683273" "unprognostic (1.01e-2)" "prognostic favorable (7.37e-4)" "unprognostic (2.17e-2)" "unprognostic (2.30e-3)" "unprognostic (1.23e-2)" "unprognostic (1.29e-2)" "unprognostic (4.53e-3)" "unprognostic (1.20e-1)" "unprognostic (5.88e-2)" "unprognostic (4.29e-3)" "unprognostic (3.53e-2)" "unprognostic (4.34e-1)" "unprognostic (1.42e-5)" "unprognostic (2.99e-2)" "unprognostic (1.61e-1)" "unprognostic (1.79e-2)" "unprognostic (2.90e-2)" 31.2 2.4 0.2 1.4 0.4 1.5 20.0 0.1 0.4 16.3 0.1 5.8 0.2 6.6 2.8 62.5 14.4 1.9 185.3 0.2 0.1 0.8 1.4 3.7 1.4 0.1 0.1 1.7 2.2 0.3 2.5 41.3 0.1 20.7 0.5 0.0 216.0 3.1 13906.8 8.8 3.0 1.3 0.1 2.8 3.3 5.2 0.1 5.4 7.6 4507.7 2.0 20.3 12.0 0.2 0.0 0.0 0.0 0.0 0.5 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.4 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 33.1 0.0 1.9 0.0 0.8 2.9 3.9 5.9 2.2 0.0 0.4 0.3 17.8 0.0 10.1 0.0 0.0 24.5 1.5 0.0 0.0 0.1 0.3 2.4 0.3 33.9 0.0 0.0 0.1 0.0 6.7 42.0 0.0 0.1 0.0 3.0 0.0 0.0 2.7 0.0 0.0 0.0 6.1 0.0 2.3 2.5 110.9 2.2 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 94.8 0.3 0.2 0.0 0.0 42.5 0.0 0.0 542.6 11.2 0.1 0.6 2.9 3.4 18.3 2.0 0.7 0.0 17.1 TNXB "TNXB1, TNXB2, TNXBS, XB, XBS" ENSG00000168477 "Tenascin XB" P22105 6 32041153-32115334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 274.8" "Cell type enhanced" "Detected in many" "Adipocytes: 54.7;Fibroblasts: 318.4;Granulosa cells: 94.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 12.4;ASC TERT1: 20.1;U-2197: 15.8;U-87 MG: 8.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-3)" "unprognostic (9.57e-2)" "unprognostic (1.16e-1)" "unprognostic (9.51e-4)" "unprognostic (5.71e-2)" "unprognostic (2.30e-1)" "unprognostic (6.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.61e-2)" "unprognostic (2.17e-1)" "unprognostic (9.70e-2)" "unprognostic (3.13e-2)" "unprognostic (2.02e-1)" "unprognostic (1.90e-2)" "unprognostic (1.01e-1)" 68.0 274.8 2.0 0.9 3.1 3.4 40.0 4.4 1.8 45.1 3.5 35.9 3.0 66.7 3.2 18.1 37.4 4.7 73.8 0.7 0.8 13.0 17.6 51.1 0.8 1.5 1.1 67.0 3.7 0.4 6.8 3.8 1.5 15.6 1.7 0.3 19.5 1.0 14.2 27.4 29.0 3.1 2.2 30.7 18.8 11.4 3.0 0.7 27.7 7.2 0.4 34.5 35.2 0.4 0.1 0.3 0.3 0.2 12.4 20.1 0.2 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.4 1.2 0.0 0.1 0.0 0.0 0.1 1.3 1.1 0.2 0.6 0.0 2.8 0.0 0.3 0.2 0.2 0.5 0.0 0.5 0.0 0.5 0.7 0.4 0.0 0.2 0.0 0.1 0.3 0.0 3.5 0.3 0.1 0.2 0.0 0.1 0.1 0.2 1.3 0.0 0.1 0.1 0.0 0.3 0.2 0.1 0.4 15.8 0.0 0.4 0.4 0.2 8.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 3.1 4.4 1.8 0.7 0.8 1.5 1.1 1.5 2.2 3.0 0.4 54.7 3.2 2.4 2.6 0.5 32.9 0.2 0.3 0.6 1.3 1.3 1.8 2.5 4.3 0.2 0.0 0.0 0.5 1.0 0.0 0.0 0.2 3.0 1.3 39.7 38.8 0.0 25.0 7.1 0.0 2.6 318.4 6.1 1.1 0.0 94.8 12.8 0.9 0.7 0.0 4.2 0.1 0.0 0.6 39.1 2.8 27.1 4.7 32.0 17.8 0.0 1.2 0.0 1.0 1.2 0.0 0.1 4.5 2.5 0.5 0.0 0.3 0.9 0.6 0.0 21.7 20.8 4.1 2.1 1.6 26.6 1.0 4.8 5.6 0.2 0.4 TOE1 hCaf1z ENSG00000132773 "Target of EGR1, exonuclease" Q96GM8 1 45340052-45343973 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 36.6;Spermatocytes: 51.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053775, HPA069119" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear bodies" Nucleoplasm "HPA053775: AB_2682259, HPA069119: AB_2686090" "unprognostic (7.20e-2)" "unprognostic (1.20e-1)" "unprognostic (7.15e-3)" "unprognostic (1.90e-2)" "unprognostic (3.33e-1)" "prognostic favorable (9.05e-4)" "prognostic unfavorable (6.12e-9)" "unprognostic (4.67e-2)" "unprognostic (4.84e-2)" "unprognostic (2.37e-2)" "unprognostic (6.03e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (2.71e-4)" "prognostic favorable (9.98e-4)" "unprognostic (1.81e-1)" "unprognostic (1.41e-2)" "unprognostic (2.08e-1)" 4.8 5.1 4.9 5.9 4.9 8.0 5.5 4.8 6.1 3.7 4.8 6.8 6.7 6.7 8.4 3.7 5.4 3.5 3.7 4.7 5.4 4.7 5.5 5.1 7.9 5.1 5.0 6.2 4.8 7.5 3.2 6.8 5.1 5.0 8.2 4.1 5.3 5.0 3.0 3.9 5.0 6.5 5.0 5.8 5.6 11.8 5.4 9.0 7.1 2.4 8.3 5.5 3.3 5.1 15.8 9.1 16.5 15.7 7.6 5.9 23.9 15.6 12.9 26.6 24.7 16.7 9.6 29.9 12.1 16.2 23.4 15.9 21.0 22.5 21.3 19.6 17.3 36.0 21.9 15.6 7.3 23.7 17.2 8.8 4.8 28.4 17.8 9.4 19.5 22.5 28.4 19.6 18.9 14.6 34.8 18.4 31.1 20.6 14.2 24.9 24.5 13.6 11.5 28.7 13.9 13.4 14.5 36.3 27.5 25.7 9.8 33.2 14.6 12.6 23.3 19.1 29.7 15.0 19.4 19.9 14.8 26.5 14.7 20.0 5.8 6.2 7.3 6.9 8.4 5.9 6.3 7.3 6.0 8.4 6.4 7.0 0.6 4.1 6.1 5.2 8.6 5.1 4.9 4.9 4.8 6.1 4.7 5.4 5.1 5.0 5.1 5.0 5.4 5.1 6.5 6.4 4.8 2.3 12.4 1.8 6.3 8.8 4.6 10.7 4.5 5.0 1.8 7.2 8.1 7.3 12.5 36.6 9.2 9.2 7.9 5.4 13.9 2.1 6.2 9.0 3.0 14.1 2.5 6.2 13.8 6.6 4.6 3.4 11.4 10.5 8.6 5.0 9.3 8.4 2.7 7.3 8.2 3.5 2.6 9.4 6.8 6.2 3.6 1.9 12.3 13.1 9.2 2.0 2.1 3.4 10.7 6.4 7.0 6.5 8.8 7.9 4.7 18.3 13.1 8.0 7.1 51.7 18.9 3.8 1.4 22.7 9.0 10.2 6.9 4.6 TOGARAM1 "crescerin, Crescerin-1, FAM179B, KIAA0423" ENSG00000198718 "TOG array regulator of axonemal microtubules 1" Q9Y4F4 14 44962190-45074431 "Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 65.7;Endometrial stromal cells: 28.6;Granulosa cells: 30.1;Respiratory ciliated cells: 38.6;Theca cells: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 4.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050849, HPA053559" Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA050849: AB_2681257, HPA053559: AB_2682190" "unprognostic (2.91e-1)" "unprognostic (4.07e-2)" "unprognostic (2.04e-2)" "unprognostic (1.05e-2)" "unprognostic (1.40e-1)" "unprognostic (1.17e-1)" "unprognostic (4.88e-2)" "unprognostic (2.67e-2)" "unprognostic (2.69e-1)" "unprognostic (1.21e-1)" "unprognostic (5.63e-2)" "unprognostic (6.49e-2)" "prognostic favorable (8.38e-4)" "unprognostic (1.62e-1)" "unprognostic (2.15e-1)" "unprognostic (3.02e-2)" "unprognostic (1.60e-1)" 4.5 6.6 9.6 2.9 13.4 3.9 5.2 10.1 13.0 6.7 9.6 4.5 2.7 6.0 5.2 4.6 10.4 4.7 8.3 11.2 8.9 7.9 4.6 3.9 3.9 7.2 8.0 7.6 6.3 8.5 7.1 5.8 8.7 5.5 3.7 16.8 4.8 6.4 12.4 4.2 3.8 5.4 7.5 4.3 4.3 6.5 9.3 8.4 9.0 12.1 3.9 5.4 4.3 19.9 3.5 5.7 5.3 1.4 12.2 14.2 3.8 4.9 10.4 9.1 10.8 2.3 3.7 3.3 5.6 7.9 4.9 6.4 9.8 3.3 10.0 3.0 3.6 2.7 2.8 2.7 8.6 4.6 2.7 8.3 5.6 5.2 8.8 10.8 7.4 1.8 1.9 3.7 9.2 5.0 5.9 2.5 1.8 5.2 4.3 2.9 12.9 2.2 8.6 12.0 5.5 2.1 5.8 8.4 9.1 5.5 6.2 3.6 5.5 6.1 4.9 7.8 3.7 3.8 3.0 3.7 3.5 0.9 5.2 4.8 0.4 1.0 0.4 0.4 0.5 0.4 0.6 0.4 0.6 0.6 0.5 0.3 0.0 0.8 0.4 0.7 0.6 0.3 9.6 13.4 10.1 13.0 11.2 8.9 7.2 8.0 8.7 7.5 9.3 19.9 15.8 16.0 14.9 0.0 4.5 0.0 0.0 0.0 0.0 0.0 15.2 10.9 0.0 0.0 20.4 16.5 0.0 11.9 13.2 0.0 1.9 10.2 0.0 65.7 28.6 6.6 0.0 0.0 0.0 5.6 8.1 8.8 0.0 16.0 10.1 30.1 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 6.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 3.8 0.0 0.0 10.4 38.6 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 9.9 6.3 34.4 0.0 0.0 TONSL "IKBR, NFKBIL2" ENSG00000160949 "Tonsoku like, DNA repair protein" Q96HA7 8 144428775-144444440 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 76.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024679, HPA046494" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nuclear bodies" "HPA024679: AB_1854441, HPA046494: AB_2679673" "unprognostic (6.68e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.88e-2)" "unprognostic (7.35e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.04e-3)" "unprognostic (7.81e-2)" "unprognostic (4.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.62e-7)" "unprognostic (3.24e-2)" "unprognostic (1.78e-1)" "unprognostic (9.11e-3)" "unprognostic (7.96e-2)" 1.0 2.1 0.4 2.5 0.4 8.5 1.3 0.4 1.3 1.7 0.0 3.4 3.5 1.6 0.2 3.9 1.4 0.6 1.4 0.3 0.3 1.4 1.7 1.3 2.3 1.3 0.6 1.7 1.5 0.4 0.9 1.5 1.1 1.6 0.8 0.1 1.5 0.8 0.5 3.3 4.4 0.6 0.1 3.9 2.2 3.8 0.8 2.3 2.4 0.1 1.4 2.3 2.1 0.3 21.2 18.6 13.7 21.7 1.0 1.7 33.0 17.6 3.4 10.4 8.1 15.0 17.9 19.6 17.5 2.7 4.9 14.2 13.4 10.7 2.3 20.2 26.6 46.5 26.1 15.9 0.6 14.3 28.1 1.7 1.5 10.9 2.1 2.6 5.0 26.5 53.0 14.3 4.2 43.4 35.5 24.5 19.4 20.4 26.7 42.6 8.9 20.3 5.9 22.6 22.9 13.0 18.4 12.3 7.8 5.2 17.6 13.2 5.9 12.7 52.3 14.5 21.7 5.0 9.9 12.0 12.3 30.2 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.4 1.3 0.3 0.3 1.3 0.6 1.1 0.1 0.8 0.3 2.5 6.4 22.4 1.6 2.9 8.9 5.2 1.0 1.2 3.1 3.5 2.9 2.3 8.6 3.7 1.8 2.1 4.1 1.3 20.2 0.0 0.9 0.4 4.3 2.7 4.3 2.4 7.2 2.4 1.0 5.3 3.8 11.7 6.1 2.5 8.5 2.9 11.4 4.5 1.7 1.0 14.6 0.0 0.9 16.7 0.7 0.3 3.0 14.2 1.9 1.2 1.1 1.0 0.5 0.8 1.2 7.1 1.2 4.0 3.9 76.5 7.7 4.1 3.0 6.6 6.4 2.8 4.6 7.8 3.4 11.2 1.2 3.1 3.3 15.9 3.9 TOP3A "TOP3, ZGRF7" ENSG00000177302 "DNA topoisomerase III alpha" Q13472 17 18271428-18315007 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, Disease variant, Dwarfism, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002449 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "CAB002449: AB_564037" "unprognostic (5.49e-2)" "unprognostic (9.04e-2)" "unprognostic (8.99e-2)" "unprognostic (7.24e-3)" "unprognostic (4.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.33e-3)" "unprognostic (6.54e-2)" "unprognostic (2.34e-1)" "unprognostic (2.74e-1)" "prognostic favorable (1.39e-4)" "prognostic unfavorable (4.59e-4)" "unprognostic (5.58e-2)" "unprognostic (8.80e-2)" "unprognostic (3.53e-2)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" 9.4 8.0 1.9 3.3 1.8 5.7 8.6 3.1 2.6 8.6 2.1 7.8 2.3 8.4 1.6 8.6 8.5 2.1 6.0 1.8 1.8 7.0 11.2 7.7 3.6 1.7 1.6 7.5 7.7 2.6 8.9 2.5 1.7 7.7 2.4 2.1 8.1 1.7 10.0 11.3 8.2 2.6 1.4 11.4 7.6 11.7 2.0 4.2 6.7 2.5 3.3 8.5 7.8 2.0 9.3 14.2 9.4 11.1 3.8 4.6 10.9 9.4 4.9 14.2 12.8 22.4 3.4 13.7 6.0 6.5 6.6 11.7 12.6 6.7 11.5 11.6 11.4 13.1 15.2 7.9 4.3 5.8 11.9 2.9 4.6 15.0 8.7 2.9 7.3 11.5 11.3 5.7 6.1 6.4 15.2 5.9 8.7 13.8 6.8 17.4 22.6 14.8 3.2 8.1 7.7 13.6 12.6 8.3 8.4 24.5 16.1 6.5 6.5 10.6 8.1 18.2 15.4 5.8 13.7 10.4 6.6 8.0 10.5 1.1 3.1 3.4 1.8 2.7 1.3 0.7 1.3 1.6 1.3 0.8 1.1 1.2 4.2 2.2 1.5 1.2 1.2 2.0 1.9 1.8 3.1 2.6 1.8 1.8 1.7 1.6 1.7 1.4 2.0 2.0 5.3 6.4 4.8 6.5 9.7 2.0 4.5 4.5 6.8 20.8 6.2 3.9 3.1 5.7 7.4 11.0 39.6 7.4 11.8 4.6 3.9 4.2 7.2 5.0 8.7 6.2 0.0 9.9 16.4 3.7 6.9 6.3 6.6 6.3 5.1 12.1 6.4 7.0 5.4 21.9 17.2 4.2 4.1 12.4 6.3 7.9 8.1 11.6 1.8 12.2 13.9 6.4 15.5 11.6 11.2 3.6 2.8 6.4 12.0 5.8 3.8 2.1 6.5 22.2 13.1 9.3 6.6 26.7 25.5 5.2 3.4 4.4 9.0 13.1 5.9 5.0 TOR1A "DQ2, DYT1" ENSG00000136827 "Torsin family 1 member A" O14656 9 129812942-129824244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012473, HPA051195" Approved Supported "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 20000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane, Vesicles" "CAB012473: AB_2240792, HPA051195: AB_2681382" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.95e-1)" "unprognostic (1.86e-3)" "unprognostic (3.67e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.10e-2)" "unprognostic (1.41e-1)" "unprognostic (4.10e-2)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (3.39e-1)" "unprognostic (1.91e-1)" "unprognostic (1.77e-1)" "unprognostic (1.99e-1)" 21.2 24.2 14.3 20.7 14.8 34.5 19.6 14.7 17.7 18.6 14.2 20.7 16.6 20.3 19.9 14.3 17.2 20.6 16.8 15.7 15.9 20.5 35.9 19.4 22.9 13.6 14.0 17.2 19.5 19.4 14.3 23.5 14.0 21.3 22.3 9.8 17.0 23.1 16.4 17.8 18.8 25.4 14.1 18.8 18.1 9.2 15.4 26.3 23.8 14.9 19.0 28.6 15.6 14.8 33.7 49.5 35.9 41.5 53.1 51.3 47.4 76.7 94.5 67.0 57.2 32.3 48.2 41.0 44.0 99.7 46.0 77.2 34.7 50.8 54.7 65.7 32.9 36.9 49.8 32.3 66.9 82.1 65.5 69.8 50.7 63.5 45.6 61.5 73.2 65.3 66.5 32.3 74.6 84.3 58.9 79.3 53.8 39.2 55.6 30.5 56.5 41.9 54.9 42.4 27.0 47.6 79.3 30.7 43.3 40.1 61.6 63.4 65.1 66.1 37.7 49.6 59.6 36.6 87.0 37.7 49.0 46.9 54.3 95.5 72.8 141.3 57.4 68.5 48.1 45.5 48.4 52.1 61.4 33.5 40.9 42.4 72.7 68.6 58.3 56.5 59.1 78.9 14.3 14.8 14.7 17.7 15.7 15.9 13.6 14.0 14.0 14.1 15.4 14.8 25.0 9.6 11.8 5.5 17.5 17.6 16.6 39.5 12.0 11.2 16.5 15.9 9.9 18.6 24.4 14.7 2.1 47.9 39.3 18.7 15.6 42.1 0.7 12.5 18.8 24.2 19.2 30.5 6.3 49.9 65.7 25.0 13.7 15.0 22.2 23.4 16.1 22.7 45.2 21.9 6.4 17.8 26.4 19.1 22.4 1.3 12.8 27.9 14.2 3.7 47.6 18.5 35.0 9.5 6.6 40.1 18.9 15.4 23.7 24.7 21.0 17.0 14.9 9.2 32.9 15.2 24.3 7.3 10.1 9.3 18.5 53.4 25.5 23.4 15.4 19.6 TP53RK "BUD32, C20orf64, dJ101A2.2, Nori-2p, prpk, TPRKB" ENSG00000172315 "TP53 regulating kinase" Q96S44 20 46684365-46689444 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 214.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 212.4;SK-MEL-30: 90.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004688, HPA015837" Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB004688: AB_426116, HPA015837: AB_1855776" "unprognostic (9.45e-2)" "unprognostic (3.73e-1)" "unprognostic (9.76e-2)" "prognostic unfavorable (6.70e-5)" "unprognostic (4.41e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (6.27e-5)" "unprognostic (9.16e-3)" "unprognostic (6.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.36e-1)" "unprognostic (5.72e-2)" "unprognostic (1.25e-2)" "unprognostic (3.37e-2)" "unprognostic (1.75e-1)" "unprognostic (1.59e-1)" "unprognostic (1.74e-2)" 6.5 7.7 6.0 7.3 5.3 6.3 8.9 4.7 6.1 6.9 2.6 6.5 4.8 7.0 4.6 8.8 6.3 5.7 5.1 5.0 6.1 6.8 7.0 5.7 11.2 5.1 5.3 6.2 5.4 7.4 6.2 6.0 5.0 7.9 6.0 6.4 7.1 6.1 6.7 9.6 5.9 6.8 4.8 7.0 7.0 12.1 6.9 13.2 8.0 5.3 11.9 10.6 6.8 6.5 12.7 8.7 17.9 15.9 18.5 15.1 16.6 17.7 16.3 22.7 16.4 24.7 8.0 32.2 26.1 14.6 20.3 19.6 23.1 20.3 19.6 7.9 12.0 31.0 8.4 22.4 24.3 20.2 212.4 20.3 24.2 15.8 15.4 10.6 15.3 12.7 21.5 13.1 19.6 19.1 31.0 35.5 14.6 18.1 29.8 17.9 16.2 19.1 15.2 14.1 21.6 11.5 21.3 42.1 90.7 9.3 15.4 21.8 15.7 26.3 15.5 17.5 19.8 14.5 19.6 24.7 15.2 15.2 12.6 36.6 16.1 28.4 16.9 15.8 19.5 19.9 18.2 19.4 16.7 19.3 19.9 17.1 2.7 22.5 14.6 25.4 25.5 17.4 6.0 5.3 4.7 6.1 5.0 6.1 5.1 5.3 5.0 4.8 6.9 6.5 12.6 9.6 13.1 5.2 14.3 50.7 54.8 45.9 39.9 9.4 22.8 21.2 7.0 18.6 27.7 9.2 12.5 42.6 23.9 10.4 27.4 28.9 214.7 13.3 25.6 17.5 13.1 16.2 5.0 23.8 73.6 29.1 23.4 14.2 22.9 14.6 11.0 12.2 25.8 15.2 4.7 16.5 32.6 14.4 28.5 49.9 22.1 13.1 37.4 4.7 17.9 8.1 21.6 6.0 6.0 34.7 4.9 16.1 8.4 62.6 15.5 31.1 18.0 10.4 6.6 8.8 26.1 87.6 15.6 35.2 61.8 88.7 19.4 26.8 13.1 59.9 TP63 "EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 69.6;skin 1: 137.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 275.4;Basal squamous epithelial cells: 335.2;Squamous epithelial cells: 173.4;Suprabasal keratinocytes: 283.1" "Group enriched" "Detected in many" 11 "cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 87.1;HBEC3-KT: 167.3;hTCEpi: 124.0;hTERT-HME1: 117.3;RT4: 185.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336" "prognostic favorable (1.07e-4)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (3.02e-1)" "unprognostic (4.38e-2)" "unprognostic (3.50e-1)" "unprognostic (1.29e-1)" "unprognostic (5.17e-2)" "unprognostic (2.78e-1)" "unprognostic (5.37e-2)" "unprognostic (2.09e-3)" "unprognostic (1.54e-1)" "unprognostic (1.87e-5)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (2.74e-3)" 0.5 0.3 0.3 0.6 0.3 0.4 18.0 0.9 0.5 23.5 0.3 0.3 0.1 0.3 10.5 69.6 1.0 0.3 0.6 0.5 0.5 0.3 0.4 1.9 1.0 0.4 0.6 0.1 0.3 0.0 0.5 10.8 0.7 17.4 0.2 0.0 20.8 18.0 42.4 137.3 0.2 0.3 0.2 0.2 0.4 3.4 0.4 23.1 0.3 12.4 17.7 18.6 54.4 0.4 2.3 4.6 0.0 0.1 0.2 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 16.6 0.6 0.1 0.2 87.1 0.0 167.3 0.0 1.4 0.0 1.9 1.3 0.4 0.0 0.0 0.3 0.2 124.0 0.2 117.3 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.3 0.2 0.0 1.0 0.3 0.0 0.2 185.1 0.2 0.1 0.2 0.0 0.0 2.5 0.9 0.2 0.3 0.2 0.1 0.2 0.0 25.3 0.3 1.1 0.5 0.1 0.8 0.6 0.0 0.2 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.3 0.1 0.1 0.4 0.2 0.0 0.2 0.1 0.0 0.3 0.3 0.9 0.5 0.5 0.5 0.4 0.6 0.7 0.2 0.4 0.4 0.2 0.0 5.3 1.0 0.9 275.4 26.8 61.9 335.2 0.0 0.9 30.1 0.7 0.0 8.5 0.0 0.0 24.9 0.1 0.1 0.0 0.2 1.8 0.0 0.1 1.1 0.0 0.0 1.3 0.2 2.8 1.4 0.0 0.1 0.0 0.0 0.0 0.1 2.4 0.0 4.8 0.0 2.0 0.0 11.9 0.4 0.3 0.7 8.8 14.0 0.6 0.0 0.0 0.5 1.4 1.6 0.0 1.2 1.6 5.6 0.0 0.0 2.8 0.0 0.0 5.3 0.9 0.5 2.4 173.4 283.1 8.9 0.6 0.2 0.0 15.2 TPM2 "AMCD1, DA1, NEM4" ENSG00000198467 "Tropomyosin 2" P07951 9 35681992-35690056 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 39012.3;tongue: 16773.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1066.2;Peritubular cells: 2072.1;Sertoli cells: 2222.0;Smooth muscle cells: 2341.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 812 "plasmacytoid DC: 398.6" "Lineage enriched" "Detected in single" 920 "dendritic cells: 398.6" "Cell line enhanced" "Detected in many" "BJ: 2309.6;fHDF/TERT166: 1289.0;hTERT-RPE1: 1399.1" "HPA047089, HPA053624" Approved NA NA 140000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (5.56e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (2.64e-4)" "unprognostic (3.34e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-2)" "unprognostic (1.18e-3)" "unprognostic (6.56e-3)" "unprognostic (2.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.51e-10)" "unprognostic (1.43e-2)" "unprognostic (8.33e-2)" "unprognostic (5.52e-2)" "unprognostic (1.41e-2)" 331.1 285.0 88.0 411.0 89.8 16.7 260.8 92.5 117.3 651.3 127.3 3498.4 217.7 1928.1 201.9 1018.0 849.7 442.4 788.5 84.8 81.1 144.0 41.0 283.1 62.2 86.1 79.2 388.4 73.7 24.1 82.6 142.3 80.5 1219.0 238.0 8.0 393.6 1988.7 39012.3 148.5 636.2 2340.8 78.6 140.1 1252.6 82.9 83.3 26.3 138.9 16773.7 21.2 1630.1 454.9 79.8 375.4 291.2 213.9 33.6 335.4 893.3 129.3 2309.6 934.4 983.0 667.9 12.2 24.2 0.4 213.0 1289.0 144.6 9.2 3.7 291.2 457.0 716.2 10.8 9.1 1054.1 11.8 540.2 2.3 102.7 1067.7 44.9 738.8 0.4 1399.1 235.7 25.3 5.6 0.8 1052.1 15.3 2.7 29.1 269.6 1.5 17.0 18.5 391.5 3.0 31.1 7.2 3.8 13.3 470.0 7.9 18.2 273.8 6.8 27.7 30.0 16.5 585.7 11.6 730.6 0.6 2.7 2.9 34.0 6.5 29.2 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.3 0.4 0.0 0.1 0.0 0.4 0.2 0.0 398.6 0.0 2.1 88.0 89.8 92.5 117.3 84.8 81.1 86.1 79.2 80.5 78.6 83.3 79.8 110.0 3.2 4.1 10.4 5.9 57.1 81.2 274.1 24.5 0.8 29.9 1066.2 619.5 4.3 42.1 7.3 0.0 12.1 116.7 1.4 0.0 21.4 4.3 20.3 488.3 80.3 2.4 4.0 2.5 5.7 104.8 332.6 99.4 18.7 2.5 142.0 181.3 1.4 32.4 1.7 4.6 1.9 48.8 3.1 77.9 32.4 283.0 24.2 67.6 9.4 6.5 11.7 1.0 3.0 0.4 8.4 0.1 2072.1 2.9 169.8 0.4 1.3 23.5 0.9 2222.0 594.8 2341.4 2.5 27.3 6.7 42.8 14.6 16.0 106.7 2.8 28.7 TPRKB "CGI-121, CGI121" ENSG00000144034 "TP53RK binding protein" Q9Y3C4 2 73729104-73737400 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 259.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035712 Approved Supported Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA035712: AB_10669674" "unprognostic (1.11e-1)" "unprognostic (2.41e-2)" "unprognostic (6.59e-2)" "unprognostic (2.31e-2)" "unprognostic (2.74e-1)" "unprognostic (2.67e-2)" "unprognostic (1.21e-3)" "unprognostic (4.96e-2)" "unprognostic (3.16e-3)" "unprognostic (3.01e-3)" "unprognostic (5.10e-3)" "unprognostic (6.06e-2)" "unprognostic (2.68e-3)" "unprognostic (5.66e-2)" "unprognostic (8.45e-3)" "unprognostic (1.82e-1)" "unprognostic (5.03e-2)" 22.7 23.1 11.8 22.3 12.3 70.2 42.7 14.5 17.2 32.7 12.6 36.5 38.7 30.2 35.8 31.0 54.9 20.2 34.0 12.0 12.5 35.5 39.2 17.3 37.0 12.7 12.2 36.1 26.7 18.5 12.7 22.6 12.7 25.0 33.9 16.1 31.1 19.0 68.1 25.7 35.5 29.1 12.7 22.3 24.9 51.8 12.1 37.0 21.3 50.9 33.7 26.3 25.2 13.1 106.1 73.3 73.4 85.5 27.2 37.6 62.2 73.5 40.0 72.2 54.2 110.8 66.0 67.0 54.0 38.2 130.7 62.6 60.6 77.6 116.0 53.4 79.2 135.7 49.8 90.6 26.6 198.3 72.8 27.2 43.6 76.4 76.3 37.4 76.9 114.7 119.8 105.1 75.5 56.4 142.5 130.6 94.9 130.5 93.9 83.6 211.6 93.8 67.2 89.8 69.1 83.1 53.1 79.5 105.6 59.8 58.7 78.6 48.5 62.4 104.7 113.6 182.6 69.1 127.6 176.9 55.9 131.2 78.4 32.5 18.2 29.1 16.5 28.5 26.4 23.9 23.6 22.3 22.1 20.9 27.0 25.5 13.1 24.6 21.5 30.1 25.4 15.8 11.8 12.3 14.5 17.2 12.0 12.5 12.7 12.2 12.7 12.7 12.1 13.1 56.3 32.1 39.8 7.2 43.1 53.2 66.8 123.0 38.7 15.0 51.8 94.9 63.5 50.1 70.6 22.0 4.2 81.3 39.7 64.0 88.0 95.4 138.9 50.2 42.7 81.9 33.6 62.1 8.6 184.9 107.9 45.1 17.9 43.4 48.7 51.3 148.2 44.3 86.7 8.4 8.7 71.2 71.2 55.6 60.0 28.9 59.0 52.1 33.8 2.8 65.0 36.6 64.9 10.1 8.3 110.7 76.9 52.3 35.6 47.8 103.4 154.9 54.4 21.8 52.6 61.7 46.2 259.3 87.8 44.8 53.0 45.6 42.8 53.9 85.4 58.2 TRAF3IP1 "DKFZP434F124, FAP116, IFT54, MIP-T3, MIPT3" ENSG00000204104 "TRAF3 interacting protein 1" Q8TDR0 2 238320441-238400897 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 75.3;Endometrial ciliated cells: 150.3;Late spermatids: 75.1;Respiratory ciliated cells: 105.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037857, HPA037858" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 49: Ciliated cells - Cilium organization" "HPA037857: AB_2675706, HPA037858: AB_10671724" "unprognostic (1.25e-1)" "unprognostic (9.08e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-2)" "unprognostic (1.43e-1)" "unprognostic (3.38e-2)" "unprognostic (1.80e-3)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (9.04e-2)" "unprognostic (6.38e-3)" "unprognostic (7.44e-2)" "unprognostic (4.78e-3)" "unprognostic (7.48e-3)" "unprognostic (1.87e-1)" "unprognostic (3.32e-1)" "unprognostic (2.07e-1)" 7.1 5.0 7.9 4.2 7.7 2.0 6.7 7.1 9.3 7.1 10.5 10.2 5.2 8.4 12.3 6.5 19.3 5.7 5.3 7.4 8.6 6.9 5.6 6.7 4.7 9.9 10.0 7.2 5.4 12.2 5.9 4.9 9.0 7.1 6.0 6.7 6.4 8.1 11.3 5.6 4.9 7.4 9.4 4.9 5.9 14.2 8.5 4.0 10.7 7.5 5.3 7.0 6.2 7.3 8.6 10.4 9.4 11.4 9.2 11.4 6.9 6.9 10.4 8.9 8.3 3.7 6.6 0.2 3.6 9.9 10.3 8.5 10.5 7.9 13.7 5.2 10.7 2.2 9.2 12.7 9.7 10.4 5.8 8.8 12.3 11.3 9.1 8.3 9.1 7.6 10.5 1.9 9.6 10.8 8.3 5.7 10.5 6.8 5.4 13.0 17.1 3.4 12.1 4.0 12.8 6.9 11.7 9.0 9.0 5.7 7.6 7.8 10.4 10.8 8.4 11.0 9.1 4.9 2.8 3.3 10.6 3.7 7.3 0.2 0.2 0.1 0.3 0.1 0.6 0.3 0.3 0.4 0.1 0.2 0.3 0.3 0.3 2.0 1.5 0.4 0.0 0.2 7.9 7.7 7.1 9.3 7.4 8.6 9.9 10.0 9.0 9.4 8.5 7.3 10.9 32.1 18.1 20.5 5.0 7.9 7.8 5.2 9.6 20.3 15.6 11.0 14.6 2.8 21.7 1.8 37.5 7.1 7.4 10.5 0.0 8.1 75.3 150.3 25.2 10.4 10.7 6.1 37.9 9.1 6.0 11.6 9.2 24.5 6.3 16.0 8.2 16.0 4.5 47.1 36.9 9.9 8.2 2.5 6.0 75.1 11.1 4.9 3.6 15.0 3.2 14.5 4.1 16.1 18.1 8.4 7.1 17.0 4.2 7.0 7.8 8.2 105.3 37.8 6.6 17.9 12.4 48.1 44.1 9.1 8.0 3.7 5.1 18.1 11.4 5.9 TRAIP "RNF206, TRIP" ENSG00000183763 "TRAF interacting protein" Q9BWF2 3 49828601-49856574 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 8.2;Spermatocytes: 15.6;Spermatogonia: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 10.8" "HPA036261, HPA036262" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA036261: AB_10673348, HPA036262: AB_2675029" "unprognostic (5.30e-3)" "unprognostic (9.41e-2)" "unprognostic (1.48e-1)" "unprognostic (6.50e-3)" "unprognostic (1.88e-1)" "unprognostic (7.68e-3)" "prognostic unfavorable (8.77e-5)" "unprognostic (4.61e-2)" "unprognostic (1.52e-2)" "unprognostic (8.61e-2)" "unprognostic (1.24e-2)" "unprognostic (7.97e-2)" "unprognostic (9.01e-5)" "unprognostic (5.84e-2)" "unprognostic (4.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.24e-1)" 1.5 1.0 1.6 1.8 2.5 6.8 1.9 0.7 1.8 2.0 0.4 2.3 1.5 1.7 1.4 2.9 1.8 1.0 0.9 1.6 0.9 0.8 0.8 0.9 4.6 0.6 0.6 2.1 1.0 0.8 1.2 1.6 0.7 1.4 2.9 2.3 1.2 0.9 2.0 4.2 2.0 2.1 0.6 1.9 1.2 7.9 1.3 5.3 1.4 1.2 4.4 1.3 1.9 0.9 10.4 12.4 17.4 17.6 1.6 2.4 14.4 12.4 5.8 25.3 24.0 15.2 11.6 25.5 8.5 7.1 17.7 13.4 18.5 14.0 18.8 14.7 12.2 19.2 16.3 13.6 0.7 15.8 15.4 1.6 2.0 20.4 10.7 3.0 6.7 22.3 14.0 17.8 11.4 15.1 26.5 20.1 14.0 12.3 20.3 14.4 11.7 14.8 4.6 14.2 8.4 14.4 13.6 11.3 8.8 12.4 10.2 22.4 5.2 16.1 19.0 22.5 24.4 13.0 33.7 27.3 8.1 21.2 14.6 0.0 0.6 0.3 0.9 0.3 0.9 2.9 0.5 2.1 0.6 1.5 0.7 1.1 0.1 1.2 1.3 0.7 0.3 0.6 1.6 2.5 0.7 1.8 1.6 0.9 0.6 0.6 0.7 0.6 1.3 0.9 0.6 3.2 0.6 1.0 1.8 1.1 0.6 1.5 2.2 2.8 1.2 1.4 2.6 0.0 0.3 3.7 0.0 4.2 1.2 1.8 0.0 2.0 4.3 0.6 0.9 0.8 0.0 3.8 1.4 1.0 8.2 2.0 1.5 0.9 0.0 5.7 1.1 0.7 3.5 0.0 0.9 2.0 0.0 0.8 0.4 4.8 2.5 0.7 1.8 1.0 1.8 1.7 0.0 0.5 0.6 1.1 0.3 1.2 4.3 0.8 0.9 0.3 0.5 3.3 0.0 1.4 1.7 15.6 9.1 2.3 0.3 1.0 1.2 1.2 4.6 0.2 TRAPPC2 "hYP38334, MIP-2A, SEDL, SEDT, TRS20, ZNF547L" ENSG00000196459 "Trafficking protein particle complex 2" P0DI81 X 13712244-13734635 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Transcription, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB004665, HPA063308" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum, Vesicles" Nucleoplasm "CAB004665: AB_425678, HPA063308: AB_2684982" "unprognostic (1.97e-1)" "prognostic favorable (8.09e-4)" "unprognostic (2.13e-1)" "unprognostic (4.18e-1)" "unprognostic (2.11e-1)" "unprognostic (2.70e-2)" "unprognostic (1.04e-2)" "unprognostic (2.08e-3)" "unprognostic (1.76e-2)" "prognostic favorable (6.35e-4)" "unprognostic (3.50e-2)" "unprognostic (8.24e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (2.36e-1)" "prognostic favorable (7.89e-5)" 6.0 5.7 12.5 6.7 13.4 7.6 6.8 13.1 14.2 10.0 10.7 10.9 6.0 11.0 6.3 8.4 9.4 5.5 5.3 13.3 13.9 7.4 8.2 7.5 12.7 12.1 11.2 11.2 9.2 5.2 7.7 5.3 12.5 8.3 6.4 10.2 7.3 5.1 4.4 7.4 9.6 8.8 10.2 10.3 9.7 3.2 14.9 9.0 7.8 2.7 11.8 8.9 9.9 11.8 9.1 6.2 10.5 26.1 8.0 5.9 3.7 8.5 7.8 6.7 6.9 5.8 11.0 14.8 13.2 6.9 8.8 11.0 13.8 12.4 8.6 15.3 20.4 11.3 16.0 5.2 6.4 15.9 20.8 8.0 7.0 14.7 17.1 13.4 6.3 11.1 15.0 26.3 7.3 16.0 16.0 21.7 10.6 7.2 11.4 15.3 14.3 14.6 10.8 5.5 10.6 13.6 14.5 12.1 11.0 16.3 13.5 10.6 7.9 6.7 6.2 11.4 5.5 13.3 13.8 19.6 6.0 10.5 6.4 19.3 6.0 11.0 18.1 8.4 18.2 13.2 14.3 17.8 5.5 12.8 11.8 16.6 11.7 22.9 6.9 13.0 18.7 11.1 12.5 13.4 13.1 14.2 13.3 13.9 12.1 11.2 12.5 10.2 14.9 11.8 8.9 9.6 6.5 7.8 22.0 15.2 10.0 14.8 9.6 16.5 16.5 13.6 11.0 15.7 14.6 9.2 12.5 14.1 49.8 14.6 21.5 10.0 17.7 17.3 11.0 9.3 12.1 12.4 20.7 13.4 19.9 11.5 14.8 21.2 9.5 16.9 16.8 12.2 11.6 20.2 20.2 14.0 8.2 12.9 14.4 6.1 12.8 13.6 8.8 10.3 12.0 8.8 44.3 31.7 17.3 15.7 18.6 11.3 17.6 9.8 15.4 23.8 8.5 14.5 6.6 8.6 18.5 4.3 4.0 11.3 17.6 17.9 28.8 16.6 13.2 12.5 TRAPPC4 "PTD009, SBDN, TRS23" ENSG00000196655 "Trafficking protein particle complex 4" Q9Y296 11 119018763-119025454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 335.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039752, HPA041371" Approved Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA039752: AB_2676664, HPA041371: AB_2677439" "unprognostic (5.26e-2)" "unprognostic (5.00e-2)" "unprognostic (2.64e-1)" "unprognostic (1.18e-2)" "unprognostic (9.42e-2)" "unprognostic (7.12e-3)" "prognostic unfavorable (2.03e-5)" "unprognostic (1.07e-1)" "unprognostic (1.12e-1)" "unprognostic (2.36e-2)" "unprognostic (4.34e-2)" "unprognostic (2.01e-2)" "unprognostic (7.49e-3)" "unprognostic (3.64e-1)" "unprognostic (1.17e-1)" "unprognostic (6.28e-2)" "unprognostic (1.32e-1)" 20.8 37.8 14.6 4.3 14.8 8.2 20.2 15.3 18.6 17.9 15.5 22.9 8.4 17.9 11.8 21.3 18.0 5.2 27.2 14.4 16.7 36.8 26.1 19.5 8.1 15.6 15.0 15.5 25.5 13.5 29.2 5.6 15.0 20.8 6.1 9.2 18.9 12.3 38.3 19.6 23.6 4.0 15.3 22.1 22.6 31.5 14.7 16.9 17.6 18.2 6.1 19.3 16.0 16.2 15.5 14.1 16.9 20.2 25.2 19.3 8.7 59.6 44.3 45.6 40.0 35.1 6.4 18.6 40.3 27.2 23.6 14.5 32.0 25.9 32.9 31.5 15.3 28.5 14.2 40.0 33.4 25.3 14.8 25.1 29.2 40.1 30.1 23.5 42.3 20.7 34.7 7.3 28.8 38.6 30.0 24.9 13.7 30.0 44.4 26.3 13.1 25.9 34.7 20.2 7.4 16.2 10.5 13.1 15.4 19.8 58.5 21.5 24.9 10.5 18.8 13.1 19.7 9.2 18.9 45.9 11.8 20.1 18.5 68.3 37.0 77.0 50.8 45.8 53.5 59.1 59.6 59.8 37.2 55.5 54.7 59.6 32.6 54.6 58.3 52.4 96.4 61.2 14.6 14.8 15.3 18.6 14.4 16.7 15.6 15.0 15.0 15.3 14.7 16.2 50.3 38.5 34.4 7.5 38.8 51.4 59.1 166.1 37.5 60.1 38.4 38.7 30.8 41.5 83.4 71.7 14.6 90.7 61.1 30.4 140.8 107.6 41.9 46.0 39.1 47.7 67.6 45.3 9.0 76.2 56.5 45.1 15.3 33.2 62.1 335.0 46.1 21.8 80.4 38.7 11.7 33.5 152.5 27.3 30.7 16.4 44.4 33.1 30.2 10.3 76.3 88.5 41.2 10.1 15.0 103.4 44.3 60.9 26.9 51.1 83.0 206.1 89.0 61.2 46.0 21.6 82.2 78.2 67.0 28.7 59.0 87.3 52.7 49.1 36.8 52.4 TRIM36 "HAPRIN, RBCC728, RNF98" ENSG00000152503 "Tripartite motif containing 36" Q9NQ86 5 115124762-115180546 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 44.2;testis: 174.3" "Group enriched" "Detected in many" 26 "Early spermatids: 2120.7;Late spermatids: 4980.3" "Cancer enhanced" "Detected in many" "prostate cancer: 9.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 5.8;non-classical monocyte: 6.5" "Group enriched" "Detected in many" 48 "dendritic cells: 5.8;granulocytes: 3.2;monocytes: 6.5" "Cell line enhanced" "Detected in many" "RH-30: 24.5;SCLC-21H: 28.3;SH-SY5Y: 19.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061321 Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "HPA061321: AB_2684479" "unprognostic (6.36e-2)" "unprognostic (2.99e-1)" "unprognostic (4.54e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (2.31e-2)" "unprognostic (5.33e-6)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (1.84e-1)" "unprognostic (1.90e-1)" "unprognostic (2.82e-13)" "unprognostic (4.95e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-1)" "unprognostic (6.80e-3)" 0.5 1.3 13.2 1.6 16.7 0.5 4.4 3.9 14.2 2.4 8.7 7.5 14.1 0.9 0.6 0.3 2.2 0.5 0.2 16.1 15.7 0.3 0.4 1.8 0.3 17.0 10.5 4.7 1.6 0.2 13.4 1.1 16.1 10.0 7.5 44.2 0.5 0.6 0.2 0.6 13.8 0.8 10.2 0.5 4.6 174.3 12.7 0.7 0.2 0.4 0.4 0.4 1.3 20.0 3.6 0.9 1.6 8.4 0.2 0.1 2.0 0.7 2.8 1.5 1.7 1.2 1.7 0.0 1.4 0.1 11.9 1.1 7.9 1.5 1.1 0.6 2.7 6.0 3.3 1.7 0.3 6.0 4.8 0.1 1.4 0.7 2.0 1.9 0.1 11.2 0.2 7.9 2.3 4.6 1.6 5.4 6.7 0.6 3.8 1.3 24.5 1.9 0.9 0.1 28.3 19.6 5.3 0.5 3.2 0.8 5.8 7.4 0.7 2.3 1.8 1.7 2.7 1.2 0.8 0.0 2.5 3.4 1.1 0.0 1.2 3.2 0.0 1.3 0.0 0.0 0.0 0.0 5.8 0.1 0.0 0.0 0.3 0.0 6.5 1.2 0.0 0.6 13.2 16.7 3.9 14.2 16.1 15.7 17.0 10.5 16.1 10.2 12.7 20.0 0.4 0.0 3.4 1.0 0.1 2.3 0.6 0.2 0.6 5.0 14.8 9.3 2.3 0.0 0.5 1.8 56.3 0.0 1.8 27.6 0.0 0.4 2120.7 3.3 0.3 2.0 3.5 0.0 39.7 1.8 0.5 1.4 6.6 1.1 1.3 0.1 0.4 0.0 2.8 5.0 14.0 15.8 2.0 1.9 18.1 4980.3 14.9 6.0 8.8 29.0 3.4 6.9 0.0 2.5 53.4 1.5 20.4 12.8 0.1 12.1 28.2 0.2 5.0 76.8 6.6 2.0 2.3 136.2 26.9 1.2 1.3 0.3 0.7 0.1 8.8 0.2 TRIM37 "KIAA0898, MUL, POB1, TEF3" ENSG00000108395 "Tripartite motif containing 37" O94972 17 58982638-59106921 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Ubl conjugation pathway" "Repressor, Transferase" "Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 62.3" "Cell type enhanced" "Detected in all" "Early spermatids: 129.2;Excitatory neurons: 96.7;Inhibitory neurons: 105.2;Late spermatids: 88.8;Spermatocytes: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 30.4" "Group enriched" "Detected in all" 5 "granulocytes: 30.4;T-cells: 8.3" "Cell line enriched" "Detected in all" 4 "MCF7: 242.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021911 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA021911: AB_10964487" "unprognostic (4.07e-2)" "unprognostic (1.71e-1)" "unprognostic (2.99e-3)" "unprognostic (1.23e-1)" "unprognostic (2.11e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.99e-6)" "unprognostic (7.83e-2)" "unprognostic (1.44e-1)" "unprognostic (2.21e-1)" "unprognostic (1.10e-3)" "unprognostic (4.79e-2)" "unprognostic (2.18e-1)" "unprognostic (1.56e-1)" "unprognostic (2.46e-1)" "unprognostic (4.27e-2)" "unprognostic (3.04e-2)" 8.8 12.3 16.2 9.5 19.3 6.8 8.2 24.8 31.4 7.9 5.2 9.0 6.7 8.8 10.7 8.4 9.7 8.9 11.5 19.5 13.8 7.6 8.2 8.9 9.0 21.4 15.2 6.1 7.7 8.6 10.3 9.4 23.0 9.4 7.0 32.9 5.8 9.2 11.1 7.4 6.2 10.8 9.4 8.6 6.5 62.3 18.2 12.1 13.3 12.7 8.4 9.0 6.5 18.7 21.4 33.3 21.9 27.5 20.5 19.0 35.3 24.0 36.9 25.3 41.4 19.6 14.4 21.1 36.1 25.3 43.3 19.0 31.5 17.7 40.5 41.8 30.4 32.6 28.9 27.1 36.1 16.8 15.8 15.4 16.1 32.5 40.8 25.8 33.0 19.1 25.4 29.7 24.9 242.4 34.0 9.5 31.5 28.9 22.0 15.0 57.1 13.7 24.0 29.7 51.7 29.9 24.8 10.2 23.2 26.4 30.4 7.8 25.9 39.5 47.6 36.5 27.6 30.5 48.5 18.5 26.8 17.5 18.7 30.4 3.7 4.5 7.2 2.7 6.7 3.6 4.7 4.6 4.0 3.9 4.0 5.4 5.3 3.4 2.8 3.0 8.3 3.1 16.2 19.3 24.8 31.4 19.5 13.8 21.4 15.2 23.0 9.4 18.2 18.7 10.3 9.6 11.0 44.4 13.2 7.9 6.0 6.5 15.4 19.7 13.2 12.2 24.1 7.2 15.6 9.2 33.3 15.1 7.8 12.0 3.9 10.3 129.2 30.8 13.8 13.7 12.0 12.8 96.7 5.6 10.6 14.0 11.7 13.5 10.8 18.0 12.1 18.9 8.7 45.4 105.2 7.2 16.2 9.1 6.9 88.8 9.9 9.3 12.4 18.7 7.2 19.9 5.2 36.2 43.5 10.2 11.3 17.7 15.1 9.9 3.3 9.7 29.1 38.8 13.1 10.9 17.3 133.1 45.0 14.0 6.3 17.8 14.7 19.7 9.1 6.8 TRIM44 "DIPB, MC7" ENSG00000166326 "Tripartite motif containing 44" Q96DX7 11 35662775-35818007 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049053, HPA057633" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Plasma membrane" "HPA049053: AB_2680613, HPA057633: AB_2683484" "unprognostic (2.73e-1)" "unprognostic (2.74e-1)" "unprognostic (1.37e-1)" "unprognostic (5.53e-2)" "unprognostic (3.91e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (5.24e-5)" "unprognostic (9.06e-2)" "unprognostic (5.29e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (8.57e-2)" "unprognostic (1.49e-3)" "unprognostic (2.15e-2)" "unprognostic (1.59e-1)" "unprognostic (1.52e-1)" "unprognostic (3.00e-1)" 12.6 10.7 16.9 12.3 16.4 6.0 11.1 18.5 21.9 10.9 8.3 13.5 10.6 10.9 10.2 9.1 11.1 11.6 11.6 16.6 17.0 18.0 14.4 11.9 12.8 16.0 16.7 10.3 15.5 11.1 7.9 13.3 16.1 10.4 11.1 27.0 9.4 11.4 11.5 8.3 12.0 12.2 17.8 14.1 11.3 6.7 17.3 12.1 14.9 9.8 13.2 11.1 8.6 19.0 20.1 16.9 26.4 12.3 19.6 29.6 0.1 18.5 21.9 22.7 20.6 19.7 13.3 26.7 17.1 24.3 25.7 15.4 9.1 21.1 25.4 17.6 17.4 28.7 23.0 11.4 26.0 22.7 23.7 22.4 23.2 13.3 36.0 25.1 24.3 9.2 45.4 9.3 24.1 12.1 24.1 11.1 14.9 4.2 14.5 16.6 68.4 14.5 21.0 26.9 18.1 15.5 27.7 19.6 21.0 14.3 29.5 19.0 27.4 28.9 23.8 16.6 21.2 15.7 15.0 0.1 23.9 23.7 22.2 0.2 0.9 0.3 0.9 1.2 0.8 1.1 0.9 0.9 0.8 1.5 1.1 1.2 0.0 1.2 1.5 1.8 0.3 0.5 16.9 16.4 18.5 21.9 16.6 17.0 16.0 16.7 16.1 17.8 17.3 19.0 67.5 60.9 72.6 78.4 68.5 26.8 57.9 19.8 74.0 221.5 45.3 38.2 58.9 55.8 45.6 25.8 204.3 55.4 72.1 70.3 33.2 62.8 18.8 78.0 74.0 62.4 51.4 39.3 151.7 71.1 25.9 49.4 74.9 54.4 58.9 107.1 49.2 53.3 42.7 84.1 134.5 57.6 16.2 65.7 37.8 13.4 36.1 70.3 19.6 84.3 76.9 72.2 72.1 121.7 171.0 53.3 50.4 37.2 59.6 90.3 50.9 75.6 48.4 173.4 98.6 71.9 52.1 88.2 81.5 46.1 26.7 52.1 47.0 58.5 54.5 59.9 TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32817997-32897824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 4.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 15.6;Inhibitory neurons: 4.5;Oligodendrocyte precursor cells: 4.5;Spermatogonia: 13.7" "Cancer enriched" "Detected in some" 28 "testis cancer: 28.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 31.4;BEWO: 94.5;Hep G2: 63.8;NTERA-2: 84.3;SuSa: 76.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: AB_2675857, HPA038142: AB_10697240" "unprognostic (2.93e-2)" "unprognostic (4.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (2.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-6)" "unprognostic (3.92e-2)" "unprognostic (9.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.65e-2)" 0.0 0.0 1.0 0.0 1.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 31.4 0.0 0.0 0.0 94.5 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.6 0.0 63.8 0.0 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.4 0.0 0.0 0.6 6.9 84.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 76.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 0.8 0.9 0.8 0.1 0.1 0.1 0.0 0.8 0.2 0.0 9.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 2.7 0.0 1.8 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 3.1 0.0 15.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.0 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.6 0.7 0.5 0.0 0.0 0.1 0.3 13.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 TRIP11 "CEV14, GMAP-210, GMAP210, Trip230" ENSG00000100815 "Thyroid hormone receptor interactor 11" Q15643 14 91965991-92040896 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002570, HPA070684" Supported Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" Nucleoplasm "HPA002570: AB_1078995, HPA070684: AB_2686295" "unprognostic (1.65e-1)" "unprognostic (2.81e-2)" "unprognostic (7.14e-2)" "unprognostic (1.12e-1)" "unprognostic (6.89e-2)" "unprognostic (1.39e-1)" "unprognostic (3.49e-3)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (7.33e-3)" "unprognostic (2.04e-1)" "unprognostic (1.21e-1)" "prognostic favorable (1.78e-6)" "unprognostic (1.78e-1)" "unprognostic (5.08e-1)" "unprognostic (7.74e-2)" "unprognostic (5.55e-2)" 10.4 10.5 4.7 8.6 8.8 7.6 10.5 10.8 7.4 11.6 13.5 10.1 10.4 9.7 6.7 12.1 7.7 10.1 10.6 3.5 5.4 13.5 12.9 8.0 9.4 6.2 7.3 11.0 25.5 19.2 4.8 11.6 6.8 9.6 9.8 10.6 11.0 8.5 11.8 8.9 7.9 10.2 6.2 8.6 15.3 13.6 6.5 11.2 16.7 15.6 11.4 10.4 5.8 10.7 22.8 22.5 14.4 15.2 24.8 38.1 21.8 35.3 27.0 17.1 19.5 13.8 36.0 15.8 25.3 31.3 13.3 29.1 19.1 17.1 37.0 24.1 5.8 17.9 20.4 13.1 18.9 21.2 17.1 14.7 20.4 30.3 25.8 18.9 27.8 8.7 11.9 17.8 27.0 31.7 12.2 5.2 6.6 22.1 16.0 14.8 27.5 8.0 15.3 36.5 10.5 9.5 28.5 16.6 11.0 14.5 36.2 10.5 36.9 19.8 13.8 20.8 16.1 15.7 25.9 14.2 23.2 11.7 25.3 9.3 9.7 20.2 13.9 9.0 13.6 13.0 14.7 13.1 7.9 23.7 14.2 14.9 9.6 14.8 16.1 14.3 14.5 4.3 4.7 8.8 10.8 7.4 3.5 5.4 6.2 7.3 6.8 6.2 6.5 10.7 66.8 54.5 79.8 57.5 32.5 16.6 30.7 31.7 21.6 61.1 39.9 40.0 115.7 34.3 54.0 38.6 73.0 44.2 41.4 29.8 17.6 72.5 13.6 58.2 81.2 53.9 32.2 30.7 58.1 46.2 32.0 51.7 39.8 56.5 37.9 68.7 32.9 37.5 24.4 43.7 74.7 40.4 32.6 25.7 11.2 14.7 62.1 30.4 7.2 51.5 41.6 56.5 47.4 66.9 92.4 44.7 29.5 54.2 26.3 39.0 31.6 23.4 56.4 70.4 59.2 76.6 50.4 105.0 65.8 19.5 17.0 72.5 30.2 79.8 32.9 35.1 TRMT10A "MGC27034, RG9MTD2, TRM10" ENSG00000145331 "TRNA methyltransferase 10A" Q8TBZ6 4 99546709-99564039 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Diabetes mellitus, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 99.5;Spermatogonia: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047601, HPA058241" Uncertain Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli, Actin filaments" Cytosol "HPA047601: AB_2680099, HPA058241: AB_2683651" "unprognostic (5.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.34e-1)" "unprognostic (1.96e-3)" "unprognostic (2.10e-1)" "unprognostic (5.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.59e-2)" "unprognostic (3.65e-2)" "unprognostic (1.57e-1)" "unprognostic (3.51e-1)" "unprognostic (7.49e-3)" "unprognostic (3.32e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (1.68e-2)" 4.3 3.7 2.0 3.1 2.6 2.2 4.4 2.6 2.9 1.9 1.5 3.6 4.3 2.7 3.9 3.6 5.8 3.4 2.3 1.8 2.5 4.9 9.8 2.4 4.4 2.6 2.5 3.3 5.9 3.7 2.3 3.7 2.9 4.1 3.6 2.8 3.9 2.2 3.9 3.7 4.5 2.7 2.7 3.5 4.4 9.9 2.4 4.3 6.1 2.7 4.4 2.9 2.0 4.3 8.2 5.4 10.1 5.7 6.0 8.4 7.8 9.6 3.7 5.8 4.1 4.9 9.4 10.9 3.7 5.6 5.9 4.4 10.9 5.1 8.6 13.7 5.4 8.0 4.4 7.6 5.5 19.6 7.8 5.4 14.4 5.7 14.0 3.0 6.4 10.0 17.5 9.4 4.5 9.4 16.4 3.5 6.5 13.8 5.0 9.5 10.2 7.2 8.5 6.8 6.3 5.8 5.3 28.3 9.9 8.5 9.3 7.8 4.9 6.9 7.2 5.5 11.1 7.0 12.4 10.0 4.9 10.9 4.7 2.7 3.9 2.1 1.8 3.8 1.7 3.5 3.3 3.3 5.2 5.8 3.5 3.2 4.9 3.3 3.4 3.0 3.9 1.9 2.0 2.6 2.6 2.9 1.8 2.5 2.6 2.5 2.9 2.7 2.4 4.3 7.2 3.2 10.3 8.8 8.7 8.2 5.6 8.4 10.2 4.3 12.1 8.6 6.4 11.5 6.6 11.0 4.2 16.8 6.1 10.6 43.0 13.8 46.8 33.5 12.1 7.2 7.2 2.1 5.3 19.3 16.4 6.9 8.6 21.6 8.2 11.0 8.2 32.6 8.5 5.0 4.6 11.1 12.2 8.1 4.1 17.0 6.5 5.0 5.4 1.9 8.4 8.7 5.2 3.5 19.7 14.1 11.0 7.5 10.4 4.8 19.0 31.9 20.6 5.9 13.1 5.7 8.1 99.5 55.0 10.2 9.5 17.5 5.5 8.1 10.6 6.6 TRPM4 FLJ20041 ENSG00000130529 "Transient receptor potential cation channel subfamily M member 4" Q8TD43 19 49157741-49211836 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.2;Hepatocytes: 81.7;Intestinal goblet cells: 114.8;Paneth cells: 77.1;Undifferentiated cells: 88.9" "Cancer enriched" "Detected in all" 4 "prostate cancer: 85.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 3.3;granulocytes: 2.8;monocytes: 4.3" "Cell line enhanced" "Detected in many" "OE19: 32.7;RT4: 60.8;SK-BR-3: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041169 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA041169: AB_2677343" "unprognostic (8.20e-3)" "unprognostic (1.41e-1)" "unprognostic (7.86e-2)" "prognostic favorable (2.88e-7)" "unprognostic (1.62e-2)" "unprognostic (9.78e-2)" "unprognostic (1.77e-2)" "unprognostic (2.90e-1)" "unprognostic (3.33e-2)" "unprognostic (3.38e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "prognostic favorable (2.53e-7)" "unprognostic (8.46e-3)" "unprognostic (2.16e-1)" "unprognostic (5.70e-2)" "unprognostic (1.00e-2)" 10.8 6.1 5.8 6.1 5.4 4.6 13.5 8.5 7.0 11.5 4.8 46.1 25.3 9.9 2.5 13.1 9.2 7.4 23.0 5.9 4.5 22.8 15.4 16.0 1.8 6.2 7.4 3.3 10.1 3.7 5.6 5.3 6.9 35.7 12.9 1.3 27.3 6.2 14.0 26.6 22.9 3.4 4.2 5.5 20.6 5.4 6.6 1.0 17.3 5.3 1.9 13.7 14.4 5.1 11.9 9.0 2.1 9.5 7.7 6.6 6.6 10.0 6.0 2.7 3.7 6.1 18.7 0.4 2.7 6.8 3.6 15.7 1.3 3.0 1.0 0.2 3.4 1.9 4.0 3.7 6.6 0.3 11.7 9.3 13.6 5.3 2.6 3.3 4.6 1.0 4.9 2.1 6.9 17.4 0.8 0.9 1.0 32.7 13.3 4.1 2.0 0.6 4.6 60.8 0.8 2.2 4.1 38.6 2.2 0.7 22.6 3.7 11.8 14.4 7.8 7.9 0.2 3.9 4.3 0.4 7.9 7.4 5.3 2.2 4.3 0.7 0.3 2.5 0.2 0.5 0.2 0.2 3.3 0.5 0.3 0.3 2.8 0.5 1.0 3.1 0.2 1.4 5.8 5.4 8.5 7.0 5.9 4.5 6.2 7.4 6.9 4.2 6.6 5.1 12.8 32.1 2.6 9.8 3.5 12.5 15.3 9.9 9.1 2.0 19.0 14.6 16.7 17.2 12.3 14.7 0.0 6.6 0.2 179.2 19.6 7.9 2.9 17.5 8.2 11.7 21.7 0.0 5.4 18.5 6.8 6.0 71.4 36.2 5.7 2.9 11.4 81.7 19.9 0.0 8.5 114.8 14.2 9.8 19.0 3.1 6.8 8.5 39.2 9.4 12.8 6.7 0.0 3.5 0.9 32.9 77.1 7.2 7.6 35.5 55.3 3.8 8.9 2.6 32.9 2.2 8.5 6.1 15.7 8.4 11.5 3.4 1.9 4.1 88.9 33.1 TRPS1 "GC79, LGCR" ENSG00000104447 "Transcriptional repressor GATA binding 1" Q9UHF7 8 115408496-115809673 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 60.8" "Cell type enhanced" "Detected in many" "Astrocytes: 758.7;Breast glandular cells: 243.2;Oligodendrocyte precursor cells: 280.5;Oligodendrocytes: 294.0" "Cancer enriched" "Detected in many" 8 "breast cancer: 49.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 4.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 47.4;SK-BR-3: 78.1;T-47d: 244.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060380, HPA071767" Enhanced Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA060380: AB_2684270, HPA071767: AB_2732185" "unprognostic (4.34e-2)" "unprognostic (4.65e-2)" "unprognostic (1.73e-2)" "unprognostic (2.57e-1)" "unprognostic (1.87e-1)" "prognostic favorable (9.42e-4)" "unprognostic (2.23e-3)" "unprognostic (2.08e-1)" "unprognostic (9.31e-2)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.16e-4)" "unprognostic (3.02e-1)" "unprognostic (2.17e-2)" "unprognostic (1.93e-2)" "unprognostic (1.64e-1)" "unprognostic (1.78e-2)" "unprognostic (3.07e-3)" 4.4 3.1 15.5 5.7 14.3 7.6 60.8 10.5 14.7 10.9 10.1 5.9 0.9 9.9 3.4 14.2 5.5 10.0 3.8 17.0 13.5 5.4 2.1 4.7 4.9 32.5 31.5 5.2 1.1 5.3 2.6 2.8 24.2 9.4 2.7 4.1 12.0 8.4 2.6 10.6 2.1 10.6 18.4 4.2 2.7 12.5 27.5 2.4 5.7 3.3 4.0 5.1 14.1 16.3 3.1 0.6 5.9 0.3 5.4 19.8 0.6 4.9 11.3 3.1 5.2 0.5 4.9 2.4 0.0 12.7 2.6 0.1 22.9 4.3 3.5 0.3 6.9 0.1 10.3 0.2 7.2 0.0 0.3 9.5 4.4 8.6 15.8 8.9 2.7 0.3 1.1 37.7 6.0 47.4 0.2 0.0 1.1 1.1 4.8 0.2 0.2 30.0 4.9 0.3 5.2 3.9 2.5 78.1 3.2 2.8 244.8 2.1 0.2 13.7 6.9 4.0 9.7 10.1 0.3 4.5 14.4 0.0 9.2 0.0 4.5 0.0 0.9 1.9 0.9 0.5 1.0 1.0 1.7 0.8 0.9 0.9 0.8 1.0 1.4 0.6 0.5 0.8 15.5 14.3 10.5 14.7 17.0 13.5 32.5 31.5 24.2 18.4 27.5 16.3 10.0 6.4 3.0 758.7 13.3 9.4 20.0 10.3 34.1 9.2 243.2 125.1 4.6 2.8 9.2 18.4 43.8 0.1 18.7 0.1 11.7 2.9 95.0 58.5 35.7 7.5 0.0 5.5 128.3 2.9 0.2 26.8 4.6 63.5 12.7 0.3 3.6 1.1 16.5 0.0 148.2 0.0 8.2 55.2 104.1 163.2 25.1 55.5 21.4 171.4 32.5 10.6 5.2 280.5 294.0 2.7 0.0 28.2 10.1 16.9 0.0 23.7 8.9 35.9 6.6 60.2 28.2 1.8 8.3 73.6 12.5 0.3 25.6 19.5 0.0 11.2 TRPV3 VRL3 ENSG00000167723 "Transient receptor potential cation channel subfamily V member 3" Q8NET8 17 3510502-3557812 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, FDA approved drug targets, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.2;skin 1: 4.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 18.7;Plasma cells: 15.9;Proximal enterocytes: 26.1;Suprabasal keratinocytes: 24.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.3;BEWO: 5.0;CACO-2: 3.1;RH-30: 11.9;T-47d: 5.2;U-266/70: 3.1;U-266/84: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069550 Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "Centrosome, Cytosol" "HPA069550: AB_2686149" "unprognostic (1.84e-4)" "unprognostic (2.25e-1)" "unprognostic (5.22e-2)" "unprognostic (3.92e-4)" "unprognostic (4.87e-3)" "unprognostic (2.96e-2)" "unprognostic (6.66e-2)" "unprognostic (4.88e-2)" "unprognostic (7.02e-2)" "unprognostic (2.68e-1)" "unprognostic (4.88e-2)" "unprognostic (3.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.12e-1)" "unprognostic (1.77e-1)" "unprognostic (8.64e-2)" "unprognostic (2.93e-2)" 0.1 0.0 1.1 0.5 1.1 0.5 0.2 0.1 1.1 0.3 0.0 0.9 2.0 0.0 0.1 0.2 0.0 0.1 0.0 0.6 0.3 0.0 0.6 0.1 0.3 0.4 0.3 0.2 0.0 0.1 0.3 0.2 0.4 0.1 1.7 0.2 0.1 0.0 1.5 4.8 5.2 0.1 0.1 0.2 0.9 0.4 0.9 0.0 0.0 0.5 0.5 0.2 0.3 1.8 3.3 0.0 0.3 0.0 0.2 0.3 5.0 0.1 0.0 0.0 0.0 3.1 0.8 0.1 1.0 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.1 0.5 0.2 0.0 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.2 0.4 0.1 11.9 0.1 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 5.2 0.1 0.0 0.0 0.1 0.1 0.0 3.1 2.7 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.1 1.1 0.1 1.1 0.6 0.3 0.4 0.3 0.4 0.1 0.9 1.8 0.2 0.0 2.5 2.9 5.8 18.7 3.9 0.2 10.2 1.2 0.9 0.5 3.5 1.5 0.2 0.0 0.0 0.3 2.6 8.9 1.9 0.0 0.3 0.7 0.9 1.6 0.0 0.0 1.6 0.0 0.9 3.7 6.1 0.9 0.0 1.1 0.0 0.3 0.3 5.0 0.6 2.7 0.0 0.0 3.8 0.4 3.1 0.8 7.2 0.0 0.1 2.2 3.1 0.5 2.3 1.2 2.5 3.4 15.9 5.9 26.1 2.3 0.2 1.0 0.0 6.9 1.8 0.0 1.5 2.9 24.6 0.5 1.8 2.8 0.9 3.7 TRPV4 "CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC" ENSG00000111199 "Transient receptor potential cation channel subfamily V member 4" Q9HBA0 12 109783087-109833406 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Charcot-Marie-Tooth disease, Disease variant, Dwarfism, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 50.8;salivary gland: 19.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 17.1;Cholangiocytes: 20.0;Cytotrophoblasts: 20.0;Kupffer cells: 19.6;Respiratory ciliated cells: 28.2;Syncytiotrophoblasts: 21.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 5 "hippocampal formation: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 7.9;BJ hTERT+: 9.5;EFO-21: 7.2;HaCaT: 14.2;HUVEC TERT2: 8.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007150 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA007150: AB_1080393" "unprognostic (2.98e-2)" "unprognostic (1.12e-2)" "unprognostic (2.33e-2)" "unprognostic (4.20e-3)" "unprognostic (6.25e-3)" "unprognostic (1.09e-2)" "unprognostic (7.95e-2)" "unprognostic (2.03e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "prognostic favorable (4.12e-5)" "unprognostic (1.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" 1.0 0.8 0.2 0.9 0.3 0.1 1.9 0.7 0.5 2.0 50.8 0.4 0.7 0.6 0.4 10.3 4.7 1.4 0.8 4.2 0.2 14.7 8.6 2.2 0.8 0.5 0.4 0.3 4.4 0.3 2.1 5.2 0.3 6.8 0.3 0.0 19.2 0.8 0.1 7.5 0.4 0.7 0.2 2.8 0.7 0.8 0.8 0.1 0.9 0.0 0.9 1.8 2.2 0.4 2.4 0.2 0.0 0.0 2.0 1.2 7.9 4.2 9.5 1.2 0.3 0.0 6.4 0.0 7.2 5.8 0.0 14.2 1.0 0.0 0.4 0.0 1.8 0.0 0.1 3.7 0.6 0.0 0.0 3.4 2.0 2.7 0.0 0.6 8.7 0.0 0.5 0.0 0.4 5.3 0.0 0.0 1.5 0.0 0.0 0.0 0.5 0.0 0.0 4.9 0.0 0.0 0.3 0.6 2.6 3.5 1.1 0.2 4.5 0.0 2.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.5 4.2 0.2 0.5 0.4 0.3 0.2 0.8 0.4 0.1 0.0 0.0 0.0 0.7 3.3 8.1 17.1 7.4 0.0 5.1 5.5 1.0 20.0 12.0 11.0 0.0 20.0 0.4 0.0 3.9 2.5 0.2 3.2 1.0 1.4 0.0 0.0 0.3 9.3 5.3 1.2 2.0 1.2 0.0 0.9 0.7 7.7 4.0 0.0 0.4 0.0 6.1 19.6 0.7 0.2 0.9 2.6 7.2 1.9 0.8 0.0 0.0 1.0 0.3 2.0 0.0 0.0 0.0 4.6 0.0 12.5 28.2 0.0 0.0 0.1 1.1 0.3 1.1 4.5 3.8 21.1 0.3 0.2 0.0 3.3 TSC1 "hamartin, KIAA0243, LAM, TSC" ENSG00000165699 "TSC complex subunit 1" Q92574 9 132891348-132946874 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011568, CAB012481, HPA074132" Supported Enhanced Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB011568: AB_732752, CAB012481: , HPA074132: AB_2686666" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (6.67e-2)" "unprognostic (4.23e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (1.96e-2)" "unprognostic (3.48e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.01e-4)" "unprognostic (1.84e-2)" "prognostic favorable (7.91e-4)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.35e-1)" "unprognostic (1.16e-1)" 11.8 14.5 6.1 5.2 6.0 9.0 12.2 8.3 6.8 13.7 3.6 13.4 5.1 12.0 6.5 10.1 11.8 5.4 14.0 6.0 5.1 13.1 10.9 11.4 6.3 4.5 5.2 18.2 12.8 7.4 16.2 9.3 4.9 13.1 7.1 8.3 11.4 5.4 14.9 15.8 12.6 7.9 1.1 14.9 12.2 22.8 4.5 6.7 17.3 14.6 8.6 11.4 12.7 4.4 8.3 9.7 13.0 10.7 13.0 12.2 24.2 10.3 17.6 11.5 11.0 16.5 9.5 19.4 4.7 20.9 17.0 21.0 15.4 11.0 11.3 9.4 8.2 6.1 19.9 13.6 15.6 9.4 8.0 13.6 8.2 14.3 17.4 11.1 13.0 16.9 11.1 10.2 12.9 15.4 8.3 7.8 17.8 12.1 7.8 9.9 24.5 11.0 5.0 10.7 6.4 10.0 12.7 7.9 6.2 15.2 14.4 5.5 13.8 18.1 10.8 11.4 7.7 5.7 13.8 18.5 10.3 5.2 8.2 2.1 2.3 2.8 3.2 3.8 3.5 0.9 1.7 2.9 1.7 1.2 2.9 2.6 0.9 3.0 1.8 0.9 3.1 1.5 6.1 6.0 8.3 6.8 6.0 5.1 4.5 5.2 4.9 1.1 4.5 4.4 14.7 22.4 27.2 35.3 10.8 7.5 6.2 5.1 9.6 26.6 11.2 9.5 29.2 7.2 10.3 11.0 37.5 15.1 13.5 7.1 13.7 11.7 45.9 18.0 22.2 12.7 16.8 15.8 53.6 7.2 24.0 14.0 14.3 25.8 8.8 27.4 9.7 5.9 9.2 25.2 59.0 10.0 10.2 7.7 7.9 133.1 15.5 12.8 12.4 19.7 10.8 9.7 7.2 30.7 47.8 12.5 7.9 11.3 12.4 9.0 8.9 7.3 16.2 24.4 19.7 19.5 15.4 22.4 20.0 11.8 8.7 21.1 11.9 23.2 10.6 11.0 TSC2 "LAM, PPP1R160, TSC4, tuberin" ENSG00000103197 "TSC complex subunit 2" P49815 16 2047967-2089491 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002225, HPA030409, HPA049679" Approved Enhanced Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Cytosol "CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: AB_2680848" "unprognostic (2.80e-1)" "unprognostic (1.01e-1)" "unprognostic (1.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.02e-1)" "unprognostic (1.03e-3)" "unprognostic (2.04e-2)" "unprognostic (6.05e-3)" "unprognostic (3.43e-1)" "unprognostic (8.94e-2)" "prognostic favorable (5.06e-4)" "unprognostic (4.32e-2)" "unprognostic (3.91e-2)" "unprognostic (2.14e-2)" "unprognostic (2.54e-1)" "unprognostic (1.51e-2)" "unprognostic (8.96e-2)" 12.6 10.0 3.8 10.2 4.6 10.9 12.6 4.5 6.1 16.7 0.9 15.3 12.4 17.4 7.3 12.0 16.0 10.9 12.6 5.9 1.3 9.6 9.0 12.0 7.7 3.1 1.5 18.4 14.8 14.7 16.5 9.2 2.7 12.4 9.1 17.7 21.3 15.6 31.1 14.4 12.8 11.4 0.1 11.4 15.7 16.2 2.6 11.7 18.6 14.5 7.8 14.0 12.8 12.5 13.5 21.4 28.9 32.5 33.7 28.1 24.3 31.7 21.7 23.4 19.7 25.7 25.4 20.5 27.6 26.2 11.0 22.0 17.5 23.1 17.3 15.5 28.5 19.2 39.6 10.7 23.0 24.0 22.4 33.5 14.3 18.9 13.9 27.9 22.3 14.4 19.0 17.7 21.0 27.0 28.9 7.1 29.8 10.1 21.2 45.3 31.6 25.7 9.4 12.1 22.1 41.3 45.2 29.4 15.3 28.2 26.8 17.5 35.5 24.5 16.5 22.0 16.5 39.0 42.7 40.8 10.2 9.7 29.6 3.2 2.7 2.8 3.1 2.1 2.8 1.8 1.9 1.7 2.5 1.8 1.3 2.1 3.5 1.6 1.7 0.6 1.4 2.2 3.8 4.6 4.5 6.1 5.9 1.3 3.1 1.5 2.7 0.1 2.6 12.5 23.8 25.6 18.9 43.8 16.8 9.2 8.1 10.1 14.8 53.8 23.7 20.2 41.8 21.5 15.3 20.2 93.8 13.0 17.3 34.5 3.9 15.2 13.1 47.8 26.3 25.6 32.5 17.4 22.8 14.1 8.0 19.7 44.9 62.1 8.8 49.0 32.2 38.7 11.4 45.4 22.4 26.6 8.2 17.6 9.9 29.3 28.3 13.8 8.8 15.9 12.1 19.0 36.0 18.6 25.7 21.4 17.5 25.9 14.4 9.4 25.4 8.9 17.8 64.7 13.1 17.2 20.4 18.3 37.7 12.9 9.8 9.3 18.8 31.6 28.9 10.6 TSEN15 C1orf19 ENSG00000198860 "TRNA splicing endonuclease subunit 15" Q8WW01 1 184051651-184123978 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, tRNA processing" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 91.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029237 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Nucleoplasm "HPA029237: AB_10671361" "unprognostic (4.54e-1)" "unprognostic (2.29e-1)" "unprognostic (2.05e-1)" "unprognostic (1.04e-2)" "unprognostic (8.72e-3)" "unprognostic (8.04e-3)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.82e-2)" "unprognostic (4.11e-2)" "prognostic favorable (4.59e-4)" "unprognostic (3.82e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.66e-10)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (2.93e-2)" "unprognostic (2.20e-1)" 16.4 17.9 21.4 14.8 23.0 19.8 17.8 22.2 27.9 17.1 15.4 20.6 11.6 17.4 28.1 15.1 14.7 12.3 21.9 21.1 22.6 14.7 15.3 16.6 19.1 23.1 20.4 11.6 17.3 15.9 11.8 17.5 22.5 17.2 13.6 21.7 15.2 15.2 36.2 14.1 11.5 17.8 19.9 14.7 15.3 14.6 22.3 28.1 21.0 22.8 18.7 16.4 12.3 29.7 83.3 28.2 39.2 41.6 30.1 31.7 96.6 40.1 77.9 64.1 61.7 30.0 35.8 54.3 40.2 50.4 41.0 38.8 44.2 38.7 69.6 78.1 23.4 28.2 19.7 34.7 60.1 103.4 32.3 21.1 67.2 29.7 60.9 25.4 38.1 95.5 55.9 144.0 59.7 43.4 97.8 46.5 72.6 107.6 30.7 60.3 65.0 113.0 37.6 26.6 35.2 52.3 54.0 39.0 102.7 41.2 51.1 57.8 20.0 39.5 83.9 26.5 61.9 190.4 141.7 87.1 36.7 52.5 86.1 33.5 16.7 24.7 33.7 27.5 30.2 24.8 32.3 35.3 35.9 18.1 24.4 33.7 3.1 54.3 25.4 31.8 39.8 35.0 21.4 23.0 22.2 27.9 21.1 22.6 23.1 20.4 22.5 19.9 22.3 29.7 15.5 48.1 8.1 22.2 26.1 11.1 12.4 17.3 16.5 8.7 18.4 13.7 32.0 10.0 17.1 12.9 4.2 42.5 31.4 3.4 54.8 33.0 1.6 6.7 13.1 15.9 6.7 22.7 30.9 41.8 48.9 20.0 14.3 11.7 32.3 18.0 18.2 34.0 31.7 3.3 32.7 8.4 10.2 13.1 29.1 2.5 21.8 16.6 33.8 13.1 21.6 19.8 64.9 42.7 91.7 35.9 4.5 19.5 45.7 13.3 5.4 71.4 6.9 12.5 13.1 11.3 24.9 46.0 44.6 23.1 13.2 22.6 34.8 19.1 9.8 10.5 TSEN2 "MGC2776, SEN2, SEN2L" ENSG00000154743 "TRNA splicing endonuclease subunit 2" Q8NCE0 3 12484421-12541549 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" Lyase "Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 43.8;Excitatory neurons: 42.8;Inhibitory neurons: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027120, HPA027125, HPA027268" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Centrosome, Cytosol" "HPA027120: AB_10600197, HPA027125: AB_10601896, HPA027268: AB_10601347" "unprognostic (5.58e-2)" "unprognostic (4.49e-1)" "unprognostic (1.49e-1)" "unprognostic (3.71e-2)" "unprognostic (9.59e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.13e-5)" "unprognostic (1.42e-1)" "unprognostic (5.66e-2)" "unprognostic (1.28e-1)" "unprognostic (2.71e-1)" "unprognostic (6.15e-2)" "unprognostic (1.41e-2)" "unprognostic (6.99e-2)" "unprognostic (4.90e-2)" "unprognostic (6.06e-2)" "prognostic favorable (3.49e-4)" 8.9 9.4 3.4 1.1 3.9 0.3 8.9 4.4 4.8 11.5 3.7 11.5 1.4 10.9 2.6 8.6 12.0 1.8 15.5 3.5 3.7 10.2 8.5 6.0 2.2 3.6 3.5 14.2 12.1 3.2 10.9 0.9 3.6 10.0 2.3 3.4 6.7 3.2 15.9 8.3 6.9 3.2 3.3 6.6 9.7 6.7 3.9 2.6 9.0 3.8 2.2 11.5 9.7 3.8 6.2 11.8 5.5 7.4 6.3 7.7 7.6 5.8 4.3 6.6 5.1 4.2 5.2 5.5 3.3 4.0 5.8 5.8 7.8 9.4 5.4 5.5 9.8 5.1 9.1 5.7 5.4 9.3 2.1 4.9 11.2 10.1 9.7 3.3 4.7 8.8 10.7 3.4 6.5 11.9 9.6 6.1 6.5 10.5 13.5 4.6 2.3 13.5 9.9 4.8 1.5 4.5 6.7 5.0 4.8 3.1 10.1 5.1 4.5 4.2 3.9 4.7 9.7 3.1 8.6 6.2 5.6 11.8 5.4 0.6 1.9 0.0 2.7 1.6 4.4 3.7 4.6 3.8 2.3 3.2 6.2 5.1 0.4 2.5 1.7 3.4 1.6 2.6 3.4 3.9 4.4 4.8 3.5 3.7 3.6 3.5 3.6 3.3 3.9 3.8 5.5 3.2 3.3 26.1 8.9 2.9 11.2 5.6 13.1 28.1 3.7 4.3 7.0 10.0 3.8 11.0 43.8 8.8 2.6 9.2 1.9 6.2 1.6 7.1 7.4 6.2 4.2 8.4 42.8 4.2 4.3 5.7 13.7 3.7 5.1 17.7 3.6 5.0 4.6 10.1 46.4 5.2 4.1 3.5 1.7 2.8 9.0 3.6 3.6 16.9 2.4 8.0 6.2 19.1 31.8 4.5 5.0 10.1 3.8 6.2 2.3 6.9 11.1 34.1 6.6 7.9 6.3 14.0 23.0 7.1 4.8 1.9 4.6 15.3 8.4 8.0 TSEN34 "LENG5, SEN34, SEN34L" ENSG00000170892 "TRNA splicing endonuclease subunit 34" Q9BSV6 19 54189938-54194536 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" Lyase "Disease variant, Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 5.0;eosinophil: 1.9;neutrophil: 4.8" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041111, HPA048208" Approved Supported Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA041111: AB_10794263, HPA048208: AB_2680313" "unprognostic (3.24e-2)" "unprognostic (2.95e-2)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (3.48e-2)" "unprognostic (4.82e-2)" "prognostic unfavorable (1.44e-7)" "unprognostic (2.38e-1)" "unprognostic (7.35e-2)" "unprognostic (1.51e-1)" "unprognostic (5.04e-3)" "unprognostic (8.98e-2)" "unprognostic (4.55e-3)" "unprognostic (2.02e-3)" "unprognostic (1.81e-1)" "unprognostic (2.81e-1)" "unprognostic (1.12e-1)" 28.5 68.2 2.2 1.3 1.8 1.3 29.5 2.4 2.4 38.8 1.8 34.7 1.1 37.1 1.9 41.0 37.8 1.5 26.3 2.1 1.7 39.1 41.3 31.5 1.3 2.2 1.7 47.9 43.0 1.8 36.0 1.3 2.0 36.2 1.3 2.0 34.0 1.9 26.7 40.5 27.7 1.2 1.3 44.1 34.3 45.0 1.7 0.5 30.9 1.8 0.7 38.9 34.2 2.2 3.3 1.7 2.5 3.1 1.3 2.0 3.9 0.6 1.0 0.9 1.7 2.1 1.1 1.1 0.0 0.9 2.5 2.5 2.6 2.3 1.4 1.1 6.2 1.0 1.1 2.0 0.5 1.1 1.1 1.9 1.1 2.0 1.3 0.9 1.3 0.0 1.7 0.9 2.4 1.4 0.4 0.2 1.5 2.9 1.1 1.4 2.6 0.7 3.4 2.4 0.1 1.7 0.0 3.5 3.0 2.5 2.6 3.1 1.1 0.2 2.8 2.7 3.4 1.4 1.9 0.9 2.6 1.3 1.2 5.0 0.6 1.9 0.2 0.5 0.4 0.1 0.3 0.1 0.3 0.4 0.4 0.2 4.8 0.0 0.3 0.4 0.0 0.2 2.2 1.8 2.4 2.4 2.1 1.7 2.2 1.7 2.0 1.3 1.7 2.2 33.1 12.8 27.7 6.8 28.2 73.5 92.0 137.7 67.2 35.4 62.9 60.8 11.8 52.9 60.9 44.1 29.2 102.5 45.4 58.8 95.9 68.7 24.0 39.4 37.0 32.5 76.8 13.7 3.8 59.7 98.2 47.5 19.9 35.3 26.6 47.7 35.7 40.6 57.8 16.8 4.9 103.7 122.1 37.0 53.6 17.2 67.7 45.0 46.2 1.0 51.8 81.9 18.6 6.0 5.9 50.4 55.9 66.5 27.6 79.8 57.8 110.5 70.0 48.9 59.2 38.7 60.8 40.1 77.2 56.7 70.2 111.0 32.8 100.3 66.5 62.3 TSEN54 "SEN54, SEN54L" ENSG00000182173 "TRNA splicing endonuclease subunit 54" Q7Z6J9 17 75515944-75524735 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, tRNA processing" "Disease variant, Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "dendritic cells: 78.4;granulocytes: 81.7;NK-cells: 87.6;T-cells: 70.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024543, HPA053097" Uncertain Approved Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA024543: , HPA053097: AB_2682043" "unprognostic (3.52e-2)" "unprognostic (2.52e-3)" "unprognostic (9.60e-3)" "unprognostic (2.55e-3)" "unprognostic (1.81e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (8.06e-6)" "unprognostic (2.33e-2)" "unprognostic (8.37e-2)" "unprognostic (9.04e-2)" "prognostic favorable (2.62e-5)" "unprognostic (7.26e-3)" "unprognostic (5.01e-2)" "prognostic favorable (7.78e-5)" "unprognostic (8.69e-2)" "unprognostic (2.03e-2)" "prognostic favorable (8.54e-4)" 11.1 14.9 2.8 1.3 4.2 2.1 12.7 5.2 3.2 14.1 2.3 19.2 2.9 11.8 0.2 23.2 15.5 3.1 8.3 2.6 3.2 27.2 18.2 17.8 2.9 5.0 4.1 12.4 29.9 4.1 18.3 1.7 3.5 20.0 2.1 0.4 17.4 3.4 9.5 24.3 22.5 2.3 4.1 25.4 20.4 14.2 3.5 5.1 18.1 1.8 2.5 15.1 17.0 4.6 21.8 25.3 2.6 7.2 2.7 2.7 14.7 6.1 6.6 14.4 13.0 35.4 3.9 32.5 9.1 3.6 12.3 11.9 14.3 11.1 7.5 7.7 33.9 26.2 4.7 23.9 11.8 7.5 36.0 2.7 13.7 6.2 5.8 2.0 14.0 20.7 31.5 6.0 2.8 36.6 46.7 19.1 9.0 31.7 30.5 26.4 23.6 25.1 8.4 9.5 19.0 17.0 13.2 30.8 14.3 8.5 11.9 17.3 3.0 6.2 20.7 13.7 12.5 22.6 14.1 19.0 6.1 32.7 6.4 20.0 4.1 14.4 82.1 9.7 56.1 11.5 34.1 62.4 10.8 7.2 26.5 50.0 0.2 47.7 9.8 26.2 21.2 27.1 2.8 4.2 5.2 3.2 2.6 3.2 5.0 4.1 3.5 4.1 3.5 4.6 9.8 9.6 9.6 15.7 13.3 26.4 10.7 19.0 17.6 15.4 11.3 11.9 2.6 20.0 11.6 9.2 4.2 13.6 78.4 25.4 11.7 17.8 6.1 7.7 6.9 10.8 18.7 14.9 14.7 17.2 18.2 8.1 29.0 7.0 81.7 10.2 8.6 8.6 13.2 32.0 15.0 16.9 24.4 4.7 11.1 4.6 4.7 9.2 16.0 5.6 12.5 15.4 87.6 14.1 23.9 14.5 13.8 7.5 29.2 22.3 23.1 13.1 5.0 7.7 13.1 5.9 7.4 15.0 33.8 21.3 24.3 7.5 70.4 14.6 22.6 8.7 TSHZ1 "NY-CO-33, SDCCAG33, TSH1" ENSG00000179981 "Teashirt zinc finger homeobox 1" Q6ZSZ6 18 75210755-75289950 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 84.9;Peritubular cells: 187.3;Theca cells: 83.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 44.4" "Region enriched" "Detected in all" 5 "olfactory bulb: 115.6" "Low region specificity" "Detected in all" HPA006982 Approved Approved Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA006982: AB_1079886" "unprognostic (2.02e-1)" "unprognostic (2.61e-2)" "unprognostic (4.03e-1)" "unprognostic (5.89e-2)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (1.24e-1)" "unprognostic (4.12e-2)" "unprognostic (9.05e-2)" "unprognostic (5.64e-2)" "unprognostic (1.69e-1)" "unprognostic (3.43e-3)" "unprognostic (1.26e-1)" "unprognostic (8.00e-2)" "prognostic unfavorable (1.71e-5)" "unprognostic (3.42e-3)" 12.0 7.7 16.3 7.1 14.1 3.3 12.1 23.5 21.0 17.4 6.3 18.1 13.8 11.4 9.3 10.0 15.9 10.4 10.9 17.0 10.4 12.1 8.2 8.0 7.3 18.8 11.5 35.4 7.2 9.2 9.7 29.7 19.3 8.9 9.3 7.9 12.5 11.1 9.2 10.6 13.7 9.3 20.1 9.4 8.8 6.3 15.5 12.3 8.2 6.4 5.3 10.9 11.0 14.1 5.4 7.0 2.2 12.8 18.8 8.9 2.2 24.2 22.6 4.0 7.4 3.2 12.9 10.8 3.0 21.9 4.5 4.8 2.9 6.9 1.4 44.4 23.2 8.3 14.5 4.3 4.9 20.0 9.4 9.1 7.2 3.3 6.5 6.2 10.1 12.5 4.7 19.1 6.6 5.2 14.3 11.4 0.9 6.3 7.6 12.9 6.6 12.9 7.6 3.9 15.9 12.1 6.8 8.8 6.8 0.8 2.0 10.4 7.6 8.7 5.9 6.0 3.9 6.2 15.9 8.7 8.6 16.6 8.1 0.0 0.5 0.5 2.1 0.2 1.4 0.4 1.0 1.8 0.8 0.6 1.5 2.2 0.3 1.5 0.2 0.8 0.4 0.7 16.3 14.1 23.5 21.0 17.0 10.4 18.8 11.5 19.3 20.1 15.5 14.1 60.2 12.8 14.0 34.3 7.1 17.0 5.6 4.8 27.9 40.8 12.2 12.6 24.4 25.8 7.9 3.7 2.1 4.6 25.6 25.4 3.9 7.5 1.2 12.5 33.9 34.4 16.9 6.9 24.9 10.0 2.2 28.8 4.6 18.2 7.0 22.5 21.0 20.5 6.4 11.8 27.7 15.0 10.2 10.8 30.9 5.9 64.7 14.3 8.8 30.0 11.2 17.9 24.7 84.9 21.3 2.9 14.7 187.3 10.6 7.3 29.7 18.4 9.1 12.1 26.3 21.3 12.2 1.4 4.8 33.1 13.2 3.6 18.2 83.2 17.9 5.4 TSPEAR "C21orf29, DFNB98, MGC11251, TSP-EAR" ENSG00000175894 "Thrombospondin type laminin G domain and EAR repeats" Q8WU66 21 44497893-44711572 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 1.0;testis: 1.0" "Cell type enhanced" "Detected in some" "Astrocytes: 1.3;Early spermatids: 3.3;Excitatory neurons: 1.1;Oligodendrocytes: 1.0" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 1.7;U-2 OS: 1.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "CAB034203, CAB034204, HPA052995" Uncertain "Secreted in other tissues" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "CAB034203: AB_1567654, CAB034204: AB_1567655, HPA052995: AB_2682008" "unprognostic (8.61e-3)" "unprognostic (2.45e-1)" "unprognostic (1.86e-4)" "unprognostic (7.87e-3)" "unprognostic (4.08e-2)" "unprognostic (1.00e-3)" "unprognostic (7.92e-3)" "unprognostic (1.56e-1)" "unprognostic (1.34e-1)" "unprognostic (1.15e-2)" "unprognostic (3.86e-4)" "unprognostic (2.13e-2)" "unprognostic (4.80e-7)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.0 1.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 1.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 TTC21B "FAP60, FLA17, FLJ11457, IFT139B, JBTS11, NPHP12, THM1" ENSG00000123607 "Tetratricopeptide repeat domain 21B" Q7Z4L5 2 165857475-165953851 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome, Mental retardation, Nephronophthisis, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 67.8;Excitatory neurons: 81.2;Inhibitory neurons: 85.5;Oligodendrocyte precursor cells: 77.9;Oligodendrocytes: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035495, HPA073293" Supported Approved Cytosol NA No "Cluster 38: Basophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA035495: AB_10672866, HPA073293: " "unprognostic (1.63e-2)" "unprognostic (1.17e-1)" "unprognostic (3.10e-1)" "unprognostic (1.60e-2)" "unprognostic (2.96e-1)" "unprognostic (2.51e-1)" "unprognostic (7.09e-3)" "unprognostic (2.81e-2)" "unprognostic (2.98e-2)" "unprognostic (7.57e-2)" "unprognostic (3.52e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.36e-4)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (2.37e-2)" "unprognostic (1.84e-2)" 5.5 4.1 3.1 3.1 3.4 2.1 5.3 6.5 4.3 6.8 2.6 5.1 2.6 6.3 2.8 3.0 7.3 2.8 5.2 3.2 3.2 5.2 4.0 4.7 4.1 3.3 3.5 8.0 5.0 4.3 4.6 4.7 3.5 6.1 4.0 7.5 4.6 4.2 9.1 4.7 4.2 4.1 3.2 4.0 4.3 4.4 3.1 5.0 4.3 9.2 3.3 4.7 6.0 3.9 4.1 2.1 11.8 6.2 11.0 7.0 3.6 8.2 5.9 4.9 5.8 4.4 2.5 8.9 3.8 3.2 4.7 5.0 8.2 4.8 6.9 6.4 4.9 6.5 4.4 13.6 6.2 6.7 0.0 4.0 2.9 5.9 5.2 8.4 7.0 5.6 9.6 6.1 9.0 2.4 7.0 7.8 6.9 4.6 6.9 9.5 9.1 3.9 6.2 8.2 9.6 6.9 4.7 1.7 8.6 6.3 2.5 7.2 3.9 12.0 5.1 6.5 5.4 3.5 4.5 5.8 5.2 5.4 7.2 3.2 0.5 0.6 0.8 0.6 1.1 1.2 1.0 0.8 0.9 1.0 1.0 1.3 0.2 1.4 1.0 0.4 1.1 0.5 3.1 3.4 6.5 4.3 3.2 3.2 3.3 3.5 3.5 3.2 3.1 3.9 11.1 3.2 9.8 32.7 12.9 9.2 8.3 5.3 22.8 21.6 7.2 6.9 12.5 4.3 9.4 5.5 33.3 3.8 20.2 4.6 0.0 3.3 2.4 67.8 15.3 8.2 7.2 13.7 81.2 1.8 4.6 11.3 11.2 21.6 6.3 12.8 10.8 8.4 13.1 15.2 85.5 7.7 6.1 8.1 4.9 3.2 10.5 7.2 10.6 44.0 5.7 9.9 9.2 77.9 58.9 1.1 6.5 12.8 14.5 6.3 4.0 7.2 34.7 22.7 6.6 15.9 10.7 7.1 12.1 8.5 3.8 2.9 12.5 8.5 5.8 4.7 TTC37 "KIAA0372, THES" ENSG00000198677 "Tetratricopeptide repeat domain 37" Q6PGP7 5 95461755-95554977 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037905 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA037905: AB_10673034" "unprognostic (5.99e-2)" "unprognostic (7.65e-3)" "prognostic favorable (2.62e-4)" "unprognostic (8.48e-2)" "unprognostic (9.49e-2)" "unprognostic (5.39e-2)" "unprognostic (1.40e-2)" "unprognostic (2.18e-1)" "unprognostic (6.88e-2)" "unprognostic (5.97e-2)" "unprognostic (6.81e-3)" "unprognostic (2.51e-1)" "unprognostic (3.30e-3)" "unprognostic (6.88e-3)" "unprognostic (3.91e-1)" "unprognostic (3.98e-2)" "unprognostic (7.90e-3)" 23.6 24.2 10.6 17.9 13.1 10.5 25.7 21.4 15.4 23.8 14.8 20.2 21.4 22.8 19.7 19.9 16.9 18.4 24.3 12.3 11.7 27.5 23.2 17.1 20.5 15.0 12.2 22.6 26.7 46.1 20.2 25.9 15.9 27.2 22.1 21.8 20.7 21.4 34.5 32.7 19.2 22.2 12.7 19.4 26.2 7.8 13.3 25.8 26.2 30.9 21.5 17.0 16.7 18.5 33.1 34.6 43.0 14.9 70.3 94.9 38.2 61.8 49.6 39.3 58.6 37.1 23.6 58.0 39.7 59.0 41.0 31.7 54.5 74.5 65.4 34.0 44.6 39.1 68.8 24.6 60.1 25.7 27.1 63.6 37.3 50.1 69.5 60.3 63.0 19.0 31.2 37.1 75.1 19.0 33.5 20.6 24.3 15.1 28.2 28.1 60.0 61.5 43.2 25.7 53.5 41.8 50.8 24.8 57.0 35.7 38.8 21.7 87.4 53.3 30.5 42.5 47.9 35.4 48.3 53.0 54.0 36.9 70.0 6.1 6.4 2.4 10.1 7.8 12.2 10.3 9.8 8.5 8.1 10.0 10.0 10.6 0.2 9.3 8.0 16.2 9.7 4.4 10.6 13.1 21.4 15.4 12.3 11.7 15.0 12.2 15.9 12.7 13.3 18.5 51.4 76.9 56.1 68.6 38.5 19.5 20.4 26.5 8.6 57.8 33.2 31.8 84.9 25.8 40.9 27.6 50.1 32.5 52.0 22.4 15.6 41.5 2.4 44.8 70.9 39.9 32.5 20.2 146.8 40.5 41.8 43.4 42.8 57.3 41.1 64.6 32.9 36.0 26.9 58.9 130.6 34.3 16.2 28.8 16.7 4.3 62.4 32.2 8.8 68.4 55.4 21.0 41.2 99.5 145.0 38.1 20.2 64.7 41.1 19.0 32.2 30.7 38.2 33.6 39.5 55.1 39.5 10.5 10.0 30.9 32.8 19.8 34.8 52.3 34.2 18.2 TTC7A "KIAA1140, TTC7" ENSG00000068724 "Tetratricopeptide repeat domain 7A" Q9ULT0 2 46916157-47076137 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 40.8" "Cell type enhanced" "Detected in many" "Late spermatids: 168.0;Microglial cells: 77.8;Oligodendrocytes: 86.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "REH: 90.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036781, HPA036782" Enhanced NA NA "Cluster 30: Non-specific - Translation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "HPA036781: AB_10673665, HPA036782: AB_10671711" "unprognostic (2.51e-1)" "unprognostic (1.43e-1)" "unprognostic (8.56e-2)" "unprognostic (1.67e-2)" "unprognostic (4.01e-2)" "unprognostic (1.03e-3)" "unprognostic (1.51e-3)" "unprognostic (3.60e-1)" "unprognostic (4.36e-1)" "prognostic unfavorable (1.36e-4)" "unprognostic (3.19e-3)" "unprognostic (1.15e-1)" "unprognostic (5.06e-3)" "unprognostic (1.30e-1)" "unprognostic (9.62e-2)" "unprognostic (1.52e-1)" "unprognostic (5.15e-2)" 8.7 16.8 2.5 6.9 4.1 18.4 6.6 3.7 3.3 6.3 10.1 6.7 12.9 4.1 1.9 14.0 5.0 3.8 3.7 2.6 3.7 6.2 5.7 12.5 10.4 6.6 4.5 4.3 16.1 4.6 4.5 5.7 5.6 4.9 5.7 4.0 12.9 4.3 1.9 12.7 12.5 2.7 3.8 10.6 10.3 40.8 4.2 29.1 10.4 0.8 14.6 4.8 8.8 5.6 39.9 14.6 4.6 1.3 6.9 8.5 19.2 10.7 14.2 6.9 6.4 22.6 23.2 26.5 10.2 19.9 8.0 16.4 6.4 13.5 5.6 51.9 5.3 2.7 11.6 24.1 2.9 10.8 10.4 3.4 15.9 8.6 10.6 8.1 5.6 10.2 10.4 17.5 3.9 14.8 54.5 11.4 5.1 42.5 3.7 90.0 7.8 47.6 6.5 10.0 5.8 5.4 19.8 39.8 3.5 8.5 7.5 22.7 14.1 7.8 6.0 5.9 9.0 10.7 4.3 13.5 5.7 13.0 4.4 0.0 1.5 0.0 0.3 0.8 0.3 1.2 0.9 0.3 0.7 1.1 0.6 0.2 0.3 0.2 0.3 1.6 0.3 0.4 2.5 4.1 3.7 3.3 2.6 3.7 6.6 4.5 5.6 3.8 4.2 5.6 2.4 22.4 12.4 32.0 22.0 6.5 4.8 5.1 9.1 1.9 4.7 2.7 4.3 11.5 5.4 7.3 0.0 8.0 16.7 29.1 3.9 5.1 52.9 27.9 10.9 5.0 6.7 7.4 24.2 7.5 11.2 8.4 13.3 15.4 8.2 4.7 1.8 9.2 16.4 0.0 18.8 9.4 0.0 29.5 15.7 168.0 4.7 24.6 5.4 77.8 18.6 22.6 1.0 17.6 86.8 22.2 11.8 6.8 22.9 3.1 38.7 4.6 12.4 3.7 0.0 8.0 5.2 6.1 6.8 12.2 5.5 4.0 11.5 2.9 7.6 4.5 TUBA1A "B-ALPHA-1, FLJ25113, TUBA3" ENSG00000167552 "Tubulin alpha 1a" Q71U36 12 49184686-49189080 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1313.3" "Cell type enhanced" "Detected in all" "Ductal cells: 1162.0;Respiratory ciliated cells: 1173.3;Smooth muscle cells: 1005.3" "Cancer enriched" "Detected in all" 9 "glioma: 942.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1660.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 3100.7;SCLC-21H: 1983.9" "Low region specificity" "Detected in all" "CAB008686, HPA039247, HPA043684, HPA063394" Enhanced Enhanced Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Microtubules "CAB008686: AB_1624202, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (3.11e-1)" "unprognostic (1.61e-1)" "unprognostic (3.77e-1)" "unprognostic (1.14e-1)" "unprognostic (4.73e-1)" "unprognostic (1.15e-2)" "unprognostic (2.56e-2)" "unprognostic (2.12e-1)" "unprognostic (3.49e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (9.79e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.07e-2)" "unprognostic (4.27e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-3)" 150.3 133.5 803.3 166.9 990.4 152.0 179.7 1083.4 882.6 185.8 692.7 466.4 54.4 406.3 166.6 140.0 342.0 193.1 156.5 784.4 1066.9 64.9 21.1 214.3 71.7 1209.8 1002.4 172.8 53.5 79.1 163.4 123.9 1136.6 173.4 126.5 259.7 104.7 267.3 37.4 107.9 125.9 865.4 1083.5 84.7 135.6 69.0 987.8 162.7 39.7 94.1 55.9 210.1 117.1 1313.3 3.2 154.4 3100.7 419.3 263.1 613.9 10.5 286.4 325.6 163.2 390.4 9.4 54.8 120.7 322.4 824.7 304.0 6.4 388.0 97.3 120.3 97.0 138.1 41.5 27.6 34.4 54.1 70.2 3.2 359.5 33.8 325.0 31.8 627.1 945.9 237.2 45.0 124.5 888.7 70.3 276.5 59.2 335.0 3.6 112.5 225.4 232.3 14.1 718.9 13.8 1983.9 1150.3 79.1 4.5 106.0 449.9 210.4 97.3 929.1 178.6 108.5 21.2 80.5 41.5 126.9 234.2 93.8 117.2 191.6 503.5 260.5 824.7 159.0 554.9 118.1 158.2 140.0 146.7 314.0 166.9 134.2 125.2 1660.9 89.9 812.8 101.1 172.8 495.5 803.3 990.4 1083.4 882.6 784.4 1066.9 1209.8 1002.4 1136.6 1083.5 987.8 1313.3 296.9 230.8 181.5 49.9 220.8 87.2 250.6 179.3 59.7 233.0 140.0 291.6 187.9 25.8 148.1 64.4 77.2 10.5 202.9 4.5 25.4 1162.0 10.0 414.9 413.6 334.2 785.8 48.0 78.2 16.2 12.8 391.5 63.2 102.4 547.9 695.0 165.6 2.8 452.0 249.0 60.6 15.5 329.6 80.7 277.6 20.7 193.6 204.2 183.2 37.5 616.6 788.9 77.2 73.4 432.6 333.3 12.8 142.6 32.5 60.4 1.5 73.3 1173.3 349.6 164.3 542.7 1005.3 15.4 31.2 20.9 99.3 15.9 266.5 40.6 12.4 95.7 TUBA8 TUBAL2 ENSG00000183785 "Tubulin alpha 8" Q9NY65 22 18110100-18146683 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 128.9;skeletal muscle: 332.2;tongue: 154.7" "Cell type enhanced" "Detected in some" "Early spermatids: 16.4;Excitatory neurons: 8.1;Inhibitory neurons: 5.6;Late spermatids: 22.9;Sertoli cells: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basophil: 2.8;eosinophil: 2.7;neutrophil: 5.0;NK-cell: 10.4" "Group enriched" "Detected in many" 7 "granulocytes: 5.0;NK-cells: 10.4" "Group enriched" "Detected in many" 5 "NB-4: 30.2;SCLC-21H: 10.9;TIME: 36.3" "Group enriched" "Detected in all" 4 "cerebellum: 54.7;olfactory bulb: 53.9" "Low region specificity" "Detected in all" "HPA043684, CAB046031, HPA063394" Approved Supported Microtubules NA NA 80000000 "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 24: NB-4 - Immune response" "Cluster 34: Spermatids - Unknown function" Microtubules "CAB046031: AB_11124541, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (1.07e-1)" "unprognostic (1.34e-2)" "unprognostic (2.79e-3)" "unprognostic (1.52e-2)" "unprognostic (2.74e-1)" "unprognostic (8.92e-2)" "unprognostic (6.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" "unprognostic (2.64e-2)" "unprognostic (1.92e-2)" "unprognostic (3.36e-1)" "unprognostic (2.90e-5)" "unprognostic (9.12e-2)" "unprognostic (6.05e-2)" "unprognostic (4.08e-2)" "unprognostic (5.61e-4)" 7.3 1.9 9.0 1.0 11.8 4.7 7.2 24.3 16.3 2.5 0.8 2.0 0.8 2.7 6.3 4.3 4.8 1.0 128.9 15.0 2.8 2.3 4.3 2.4 3.5 0.6 9.0 2.3 4.4 2.7 14.5 0.6 0.8 2.5 0.5 2.8 4.4 0.6 332.2 4.4 2.6 0.7 1.5 4.2 4.7 52.3 11.5 0.8 6.5 154.7 1.0 2.0 2.2 12.5 0.6 1.1 1.2 1.4 1.8 0.5 0.4 0.6 0.3 1.4 0.8 0.9 1.1 0.9 2.2 0.7 0.4 0.6 2.2 0.4 0.3 0.8 1.6 2.2 1.7 0.9 1.0 1.0 1.0 0.7 0.8 0.8 0.6 0.5 2.0 0.9 0.6 0.9 0.6 3.4 1.0 30.2 1.0 0.5 0.5 0.9 0.5 0.2 0.7 1.1 10.9 1.1 0.6 1.9 1.0 0.5 0.6 4.8 36.3 0.9 1.0 1.0 0.4 2.2 1.3 0.7 0.9 1.4 0.6 2.8 0.7 2.7 0.5 0.6 0.7 0.4 0.4 0.3 0.4 0.6 0.7 0.4 5.0 10.4 0.4 1.0 0.8 17.1 9.0 11.8 24.3 16.3 15.0 2.8 0.6 9.0 0.8 1.5 11.5 12.5 0.2 0.0 1.7 1.6 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.3 4.7 0.0 0.0 0.0 2.1 0.0 0.0 0.4 0.0 0.3 16.4 0.2 0.1 0.4 0.0 0.0 8.1 1.1 0.0 0.3 0.0 0.2 2.5 0.1 0.7 0.0 0.1 3.3 5.6 0.0 0.0 0.3 0.0 22.9 0.3 0.1 0.0 0.0 0.2 0.1 1.0 3.5 1.7 0.6 0.1 0.4 0.0 0.0 0.4 0.1 0.0 0.2 6.6 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.0 TUBB "M40, MGC16435, OK/SW-cl.56, Tubb5" ENSG00000196230 "Tubulin beta class I" P07437 6 30717435-30725538 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 2296.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005417, CAB012406, HPA043640, HPA046280" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 170000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB005417: AB_2241191, CAB012406: AB_2210370, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (1.01e-1)" "unprognostic (2.33e-1)" "unprognostic (2.17e-3)" "unprognostic (1.92e-2)" "unprognostic (1.56e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (5.97e-4)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (2.18e-3)" "unprognostic (1.27e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (2.62e-8)" "unprognostic (8.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.49e-1)" "unprognostic (2.50e-1)" 229.5 164.8 74.6 243.5 81.8 541.0 186.9 46.2 367.7 228.7 87.0 250.3 87.6 333.0 174.5 246.3 227.0 158.5 245.3 73.5 119.7 137.8 236.6 205.3 369.2 80.5 74.8 467.5 138.1 74.4 97.0 194.4 99.2 145.2 194.4 82.4 160.2 194.6 185.7 211.9 159.4 371.0 57.5 195.0 172.8 77.8 94.0 620.4 142.4 98.6 487.6 222.3 213.8 63.5 2281.7 1027.3 2650.0 1458.4 733.2 1265.2 568.2 396.9 469.5 943.3 863.5 1329.2 703.9 1494.1 1105.1 1408.1 1877.8 805.3 2160.6 1968.0 160.3 892.5 1321.1 461.4 207.3 1306.7 345.8 2550.0 1223.9 943.6 455.9 416.0 443.6 967.1 1493.3 2058.1 1270.4 294.1 1844.8 1398.2 2719.0 249.3 377.3 604.1 948.6 102.6 708.5 911.6 1564.5 1071.4 940.8 1516.7 969.0 911.2 354.7 1625.5 1148.3 422.4 880.6 2712.0 1526.0 614.5 917.7 835.3 1735.4 2101.3 538.8 2494.6 3548.7 119.8 115.6 122.8 187.3 182.5 218.8 166.1 152.3 188.8 111.7 113.0 143.2 163.3 46.8 165.1 222.4 227.7 180.8 342.5 74.6 81.8 46.2 367.7 73.5 119.7 80.5 74.8 99.2 57.5 94.0 63.5 215.8 131.4 47.3 21.5 214.9 576.2 358.4 698.6 434.2 72.7 234.2 312.8 114.9 244.5 238.7 171.0 39.6 811.9 198.7 133.4 311.0 1091.0 9.1 69.1 261.6 370.8 163.6 1322.1 28.2 1061.1 2296.1 471.5 95.3 140.2 207.3 643.6 298.4 267.8 955.2 109.4 25.0 185.3 376.4 454.5 689.6 24.4 402.6 295.8 321.9 30.9 774.0 192.6 246.1 20.1 23.0 1087.0 90.7 237.3 304.6 199.5 117.9 245.9 66.6 65.4 118.3 124.0 838.6 58.0 126.5 447.0 430.6 220.4 244.0 224.9 253.2 229.0 TUBB2A "dJ40E16.7, TUBB, TUBB2" ENSG00000137267 "Tubulin beta 2A class IIa" Q13885 6 3153497-3157544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 364.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 516.5;Suprabasal keratinocytes: 368.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.2;monocytes: 1.6;T-cells: 3.2" "Cell line enhanced" "Detected in all" "AF22: 241.1;CACO-2: 247.6;SuSa: 365.5;WM-115: 280.1" "Low region specificity" "Detected in all" "CAB015339, HPA043640, HPA046280" Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 61: Squamous epithelial cells - Keratinization" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB015339: AB_2210539, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.57e-1)" "unprognostic (9.86e-3)" "unprognostic (5.90e-3)" "unprognostic (7.98e-3)" "unprognostic (4.02e-3)" "unprognostic (1.67e-1)" "unprognostic (1.82e-3)" "unprognostic (7.53e-2)" "unprognostic (1.48e-3)" "unprognostic (9.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.42e-2)" "prognostic favorable (4.65e-4)" "unprognostic (2.39e-2)" "unprognostic (1.79e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (1.61e-4)" 58.8 17.8 266.1 19.3 251.1 67.5 47.8 130.1 287.5 32.7 10.0 78.0 24.2 50.8 28.0 90.6 23.5 21.5 29.4 248.3 364.3 31.1 67.0 16.4 11.0 292.6 212.2 15.5 39.4 2.2 56.3 23.9 334.3 17.5 8.2 49.9 52.2 15.6 22.3 151.4 34.9 41.7 131.6 7.7 41.0 9.5 204.4 6.4 10.0 11.8 9.6 23.6 51.2 169.4 55.9 45.3 241.1 53.6 30.6 34.0 14.5 119.8 44.7 80.6 115.7 247.6 18.4 27.4 72.9 115.5 80.2 26.0 86.6 26.8 28.0 134.1 57.7 9.4 11.4 77.0 31.6 1.5 8.4 35.1 31.1 85.1 5.3 28.9 37.3 10.6 33.7 8.8 74.2 25.1 14.9 2.8 207.2 16.0 58.3 12.4 22.6 18.9 28.0 27.4 57.6 52.9 30.5 8.5 179.7 365.5 19.1 2.0 76.0 53.9 56.7 117.3 65.8 3.2 4.6 18.8 19.7 7.0 280.1 0.0 1.1 0.0 2.2 1.6 2.4 3.2 2.1 3.1 0.5 0.6 1.0 2.0 0.3 0.4 1.3 0.2 3.2 1.2 266.1 251.1 130.1 287.5 248.3 364.3 292.6 212.2 334.3 131.6 204.4 169.4 125.3 16.0 13.1 43.1 31.6 311.4 63.3 87.0 132.6 105.6 32.0 134.6 20.4 42.9 62.7 12.9 16.7 6.0 53.4 87.0 217.2 54.0 60.9 46.7 29.6 40.6 73.1 322.3 59.9 182.4 50.4 96.2 185.0 57.9 34.9 10.1 12.5 55.6 50.8 516.5 73.0 103.9 73.2 6.3 164.4 32.9 20.8 36.7 129.9 24.4 72.7 261.0 0.0 18.1 23.0 103.4 181.8 15.4 15.8 34.9 126.3 40.4 50.3 86.2 6.6 95.6 87.9 32.4 14.9 140.6 368.5 6.2 58.9 6.4 60.0 54.7 TUBB2B "bA506K6.1, DKFZp566F223, MGC8685" ENSG00000137285 "Tubulin beta 2B class IIb" Q9BVA1 6 3223324-3231730 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 387.9;choroid plexus: 154.0" "Group enriched" "Detected in many" 4 "Distal tubular cells: 414.8;Horizontal cells: 430.7;Muller glia cells: 847.3;Skeletal myocytes: 350.1" "Cancer enriched" "Detected in many" 9 "glioma: 216.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 541.9;CACO-2: 415.3;NTERA-2: 268.0;RPMI-8226: 277.7;SCLC-21H: 797.7;SH-SY5Y: 390.2;SuSa: 245.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043640, HPA046280" Supported Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 5: Muller glia cells - Visual perception" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.66e-2)" "unprognostic (3.41e-1)" "unprognostic (5.92e-3)" "prognostic unfavorable (1.94e-4)" "unprognostic (6.81e-2)" "unprognostic (3.26e-2)" "unprognostic (9.03e-3)" "unprognostic (8.33e-2)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" "unprognostic (3.78e-3)" "unprognostic (3.34e-2)" "unprognostic (2.03e-2)" "unprognostic (6.24e-3)" "unprognostic (6.04e-2)" "unprognostic (3.58e-4)" "unprognostic (2.30e-3)" 4.0 7.2 298.1 8.1 324.5 1.0 5.0 348.4 387.9 9.9 154.0 17.0 2.4 4.2 45.5 2.4 3.3 3.8 4.6 258.8 356.9 11.6 1.0 1.4 8.1 363.3 349.9 1.1 5.7 0.0 35.1 4.4 354.5 3.7 2.6 65.3 10.8 4.6 6.2 3.9 6.1 7.3 337.2 0.7 4.5 1.0 369.1 2.3 0.9 1.6 5.7 2.6 5.6 383.9 0.0 8.2 541.9 164.2 0.6 0.2 0.9 5.1 7.4 20.8 45.0 415.3 2.0 0.9 5.6 5.7 0.0 1.3 212.8 0.7 12.0 1.6 98.3 0.2 0.0 33.2 1.1 0.1 6.1 3.1 0.0 2.3 0.0 7.6 1.4 0.5 6.8 1.2 7.6 0.3 1.5 0.4 268.0 1.0 17.6 0.6 26.3 277.7 2.9 0.8 797.7 390.2 0.3 1.7 4.3 245.9 3.2 0.0 0.0 1.9 89.9 6.3 2.2 51.6 0.1 0.0 0.8 0.1 30.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 298.1 324.5 348.4 387.9 258.8 356.9 363.3 349.9 354.5 337.2 369.1 383.9 3.6 0.0 0.0 109.4 1.9 8.7 2.3 1.8 4.6 63.5 3.9 31.9 40.1 5.7 0.3 7.3 16.7 0.7 1.0 0.9 414.8 15.4 5.8 2.7 3.3 7.6 66.7 0.0 2.4 3.5 1.2 18.7 7.1 3.9 0.0 0.5 0.7 0.6 3.0 430.7 19.4 1.0 24.4 0.0 12.4 7.1 0.3 1.0 92.5 9.4 3.6 847.3 0.0 37.2 21.6 12.0 0.1 0.0 8.4 3.9 0.2 2.0 0.0 43.1 0.0 350.1 19.1 1.3 6.2 3.1 2.7 0.8 0.6 0.0 0.6 1.1 TUBB3 "beta-4, CFEOM3, CFEOM3A, FEOM3" ENSG00000258947 "Tubulin beta 3 class III" Q13509 16 89921392-89938761 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 313.3" "Cell type enhanced" "Detected in some" "Astrocytes: 20.2;Ductal cells: 28.7;Excitatory neurons: 37.9;Exocrine glandular cells: 21.4;Gastric mucus-secreting cells: 27.0;Inhibitory neurons: 45.1;Pancreatic endocrine cells: 49.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 9 "B-cells: 2.5" "Cell line enhanced" "Detected in many" "A549: 421.3;SCLC-21H: 424.9;SH-SY5Y: 433.8" "Low region specificity" "Detected in all" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA 89000000 "Cluster 24: B-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (7.08e-2)" "unprognostic (3.37e-4)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" "unprognostic (8.01e-2)" "unprognostic (3.12e-2)" "unprognostic (4.04e-3)" "unprognostic (1.12e-3)" "unprognostic (1.22e-2)" "unprognostic (6.06e-2)" "unprognostic (1.99e-2)" "unprognostic (1.38e-2)" "unprognostic (7.57e-2)" "unprognostic (1.27e-3)" "unprognostic (3.70e-2)" "unprognostic (3.05e-1)" "unprognostic (1.91e-2)" 5.7 24.8 99.4 12.1 93.3 3.4 2.1 100.5 127.6 3.3 0.0 18.4 3.7 9.7 0.2 3.6 2.3 8.8 5.5 88.6 313.3 13.3 0.9 4.1 7.1 208.8 132.7 3.9 3.2 0.4 55.1 1.8 266.2 3.0 2.6 24.8 10.6 0.4 0.6 5.2 8.0 12.7 74.2 1.3 7.2 38.0 183.4 1.0 2.5 0.3 5.2 7.3 5.3 82.5 30.1 421.3 152.6 173.9 17.9 170.8 6.8 181.0 31.0 105.8 48.2 57.2 53.5 89.6 93.6 136.8 74.3 112.1 148.9 26.7 26.3 22.7 15.5 0.7 32.5 383.7 6.0 0.0 67.6 98.4 7.9 161.9 14.0 136.8 88.4 5.9 9.2 2.5 122.3 288.6 1.2 31.5 274.3 11.2 237.3 0.1 54.1 9.5 131.8 8.1 424.9 433.8 251.2 4.4 137.1 27.5 15.0 1.9 110.9 142.8 156.9 197.3 185.3 1.4 19.6 35.2 150.2 11.5 260.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 99.4 93.3 100.5 127.6 88.6 313.3 208.8 132.7 266.2 74.2 183.4 82.5 0.4 0.0 0.0 20.2 0.0 0.0 0.0 0.0 3.4 1.8 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.0 28.7 8.2 0.5 2.6 3.8 4.9 0.0 37.9 21.4 0.7 6.1 27.0 0.7 0.0 0.0 0.0 0.0 0.2 5.0 45.1 0.1 0.0 0.0 0.0 16.8 0.3 0.2 0.0 9.4 0.0 0.3 0.0 16.1 9.2 49.2 0.0 0.4 0.4 0.0 0.0 0.1 0.0 1.4 0.0 0.0 5.1 0.2 0.4 3.0 0.0 1.0 0.1 0.0 0.2 0.0 TUBG1 "TUBG, TUBGCP1" ENSG00000131462 "Tubulin gamma 1" P23258 17 42609641-42615238 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 173.8" "Cell type enhanced" "Detected in all" "Early spermatids: 670.6;Erythroid cells: 286.9;Late spermatids: 560.5;Spermatocytes: 347.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB004608 Enhanced NA Yes "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" "CAB004608: AB_628417" "unprognostic (1.00e-1)" "unprognostic (5.57e-2)" "unprognostic (1.79e-2)" "prognostic favorable (8.99e-4)" "unprognostic (2.86e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (1.08e-8)" "unprognostic (2.62e-3)" "unprognostic (5.67e-2)" "unprognostic (1.83e-1)" "unprognostic (3.79e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.48e-5)" "unprognostic (2.64e-1)" "unprognostic (3.52e-1)" "unprognostic (2.61e-3)" "unprognostic (1.97e-2)" 23.0 30.4 17.7 20.4 18.4 51.7 19.0 17.8 25.4 17.6 21.1 24.0 16.6 20.7 13.4 35.6 16.3 10.1 43.6 18.5 19.8 24.8 27.1 19.1 18.0 20.3 18.0 12.5 48.7 29.9 20.2 21.0 20.0 19.7 14.9 10.5 19.1 18.3 60.7 29.0 18.1 27.2 15.9 19.3 29.8 173.8 21.4 27.6 14.8 36.3 20.6 21.7 19.9 19.7 117.8 288.8 112.1 124.0 70.5 47.8 97.7 133.4 87.2 205.6 158.8 177.4 76.9 80.2 92.8 105.9 178.5 171.9 124.2 178.0 149.7 225.9 142.6 64.1 168.5 299.3 34.6 73.8 87.6 38.1 54.0 251.1 75.8 50.6 131.9 119.0 119.7 77.2 155.9 326.7 176.3 66.2 59.3 176.7 139.1 81.8 164.2 130.5 91.7 136.6 158.9 74.5 78.0 76.9 63.6 113.9 233.6 70.2 88.5 197.9 131.0 169.2 207.0 111.2 169.0 126.2 108.6 70.6 144.2 1.7 13.1 3.1 10.6 25.1 11.6 14.9 9.8 11.4 15.7 15.0 10.4 10.5 0.4 12.7 27.4 44.1 13.5 10.4 17.7 18.4 17.8 25.4 18.5 19.8 20.3 18.0 20.0 15.9 21.4 19.7 14.9 16.0 4.2 3.9 12.8 17.6 16.3 49.4 12.0 14.1 14.6 16.5 18.8 14.3 24.1 7.3 4.2 45.8 7.0 10.2 39.2 35.2 670.6 15.1 13.7 20.1 9.6 286.9 7.2 54.4 78.6 15.7 15.8 10.7 2.5 16.9 15.7 15.9 40.2 20.2 6.4 13.7 38.7 6.3 10.8 560.5 22.7 9.7 17.8 8.4 26.4 17.7 10.3 4.0 3.8 42.3 6.2 21.8 41.5 15.2 15.1 76.6 18.1 10.9 59.2 7.1 43.5 347.8 128.0 27.3 28.6 20.1 8.5 15.0 14.0 15.6 TUBGCP4 "76P, FLJ14797" ENSG00000137822 "Tubulin gamma complex associated protein 4" Q9UGJ1 15 43369221-43409771 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 55.5;Rod photoreceptor cells: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043212 Approved Supported Centrosome NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" Centrosome "HPA043212: AB_10796690" "unprognostic (1.34e-2)" "unprognostic (3.57e-2)" "unprognostic (4.27e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-2)" "unprognostic (3.37e-1)" "unprognostic (1.18e-1)" "unprognostic (3.86e-2)" "unprognostic (1.91e-1)" "unprognostic (2.05e-1)" "unprognostic (2.09e-2)" "unprognostic (2.91e-2)" "unprognostic (5.65e-1)" "unprognostic (1.73e-1)" "unprognostic (7.49e-2)" "unprognostic (1.72e-1)" "unprognostic (2.28e-1)" 3.9 4.3 5.1 3.7 6.9 4.8 5.1 8.4 8.4 5.3 6.4 5.0 4.8 4.5 3.5 5.8 4.5 2.9 4.9 5.6 5.6 4.7 5.9 3.9 4.6 5.6 5.7 5.2 6.1 8.3 5.2 3.7 5.9 5.1 5.2 11.1 5.1 3.7 9.7 4.6 5.2 4.9 5.4 4.4 4.9 4.1 5.7 6.1 4.5 9.8 5.5 4.6 5.1 6.4 18.2 5.6 13.3 13.7 12.9 13.9 10.3 10.2 7.3 13.9 14.0 18.0 11.1 11.3 15.2 8.8 19.5 29.4 28.3 18.2 16.3 19.0 26.9 29.5 30.2 15.9 10.7 20.4 17.6 7.6 17.9 14.4 20.0 11.0 11.5 18.5 28.4 9.6 10.4 6.3 16.4 15.7 6.3 29.6 22.1 22.0 17.5 15.9 9.2 17.1 35.5 12.1 12.4 23.8 4.1 8.4 14.1 15.8 9.5 13.2 13.5 18.3 22.7 9.9 12.5 19.6 12.1 29.0 15.1 0.1 2.5 13.8 3.7 2.9 2.7 3.6 2.8 2.6 5.3 3.2 2.0 2.9 0.3 5.3 1.6 2.8 3.2 2.4 5.1 6.9 8.4 8.4 5.6 5.6 5.6 5.7 5.9 5.4 5.7 6.4 6.5 19.2 14.5 12.1 14.9 11.0 16.3 4.5 5.2 30.9 8.8 7.4 1.7 18.6 10.8 16.5 22.9 16.1 6.5 8.5 7.9 12.2 28.7 9.4 15.3 8.8 14.4 15.4 17.3 9.9 14.7 10.4 5.6 10.4 11.4 15.9 10.0 11.4 6.9 55.5 13.8 10.6 8.2 7.6 5.6 43.6 15.2 6.1 3.6 4.7 7.7 13.1 22.6 17.1 9.2 11.0 9.4 12.4 5.8 20.1 12.7 6.1 9.5 57.1 6.6 19.1 10.2 25.0 14.5 9.2 8.9 11.5 9.8 11.2 17.7 16.9 TUBGCP6 "DJ402G11.6, GCP6, KIAA1669" ENSG00000128159 "Tubulin gamma complex associated protein 6" Q96RT7 22 50217689-50245023 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043928 Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 50: Non-specific - Ribosome" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "HPA043928: AB_10960352" "unprognostic (4.26e-2)" "unprognostic (1.62e-3)" "unprognostic (2.86e-2)" "unprognostic (2.40e-2)" "unprognostic (1.34e-1)" "unprognostic (2.96e-3)" "unprognostic (2.73e-1)" "unprognostic (2.21e-2)" "unprognostic (2.67e-1)" "unprognostic (1.00e-2)" "prognostic favorable (5.75e-4)" "unprognostic (2.90e-3)" "unprognostic (1.90e-2)" "unprognostic (1.04e-2)" "unprognostic (9.71e-2)" "unprognostic (7.53e-2)" "prognostic favorable (3.18e-5)" 11.1 14.9 10.3 12.3 10.0 13.2 12.2 13.2 14.9 16.6 9.9 12.7 9.8 15.2 6.7 10.1 15.6 10.2 11.3 9.0 8.0 15.1 12.7 11.9 16.4 9.6 7.8 18.3 23.4 12.2 22.2 8.1 7.6 16.4 4.6 5.9 15.9 8.9 14.9 12.9 16.4 6.1 5.7 17.1 15.9 12.4 8.2 15.5 19.7 7.0 10.1 12.7 10.7 11.6 8.0 7.0 12.6 15.2 9.8 9.2 8.6 8.9 5.8 6.2 7.5 5.1 6.6 7.0 6.4 9.1 5.6 9.1 6.3 9.4 2.9 7.2 19.8 6.9 32.7 6.6 6.7 14.6 13.0 13.2 8.4 8.0 6.6 10.5 9.3 14.8 7.2 18.5 5.8 8.3 11.1 12.3 4.2 3.7 4.6 13.4 7.0 14.6 5.2 9.9 4.6 9.1 7.0 12.8 3.7 5.2 6.9 8.3 9.7 9.2 6.6 8.1 6.5 19.4 4.0 8.6 8.0 6.4 6.2 0.7 0.9 0.7 2.2 0.8 1.6 1.0 1.6 2.4 1.0 1.1 1.4 1.7 1.0 1.1 0.7 1.5 2.4 1.2 10.3 10.0 13.2 14.9 9.0 8.0 9.6 7.8 7.6 5.7 8.2 11.6 8.4 9.6 17.2 22.9 10.8 6.4 2.8 6.8 5.2 9.3 9.4 11.0 8.1 7.2 8.3 11.0 16.7 4.6 12.5 8.2 3.9 4.2 2.0 7.2 7.4 6.4 9.0 7.0 13.9 3.6 3.2 8.4 17.9 9.3 6.3 11.5 5.3 7.1 4.4 6.7 12.0 8.1 6.1 9.8 6.2 3.8 9.6 8.6 7.2 9.4 4.6 3.2 9.2 6.6 10.0 4.6 4.9 6.8 11.5 3.9 10.1 2.6 13.2 11.0 6.6 7.8 7.0 10.8 10.0 6.2 5.5 3.4 12.4 10.4 7.7 3.1 TWIST1 "ACS3, bHLHa38, BPES2, BPES3, CRS, CRS1, H-twist, SCS, TWIST" ENSG00000122691 "Twist family bHLH transcription factor 1" Q15672 7 19020991-19117636 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 25.2" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 92.8;Fibroblasts: 73.4;Langerhans cells: 30.3;Smooth muscle cells: 34.4;Theca cells: 29.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 6 "SH-SY5Y: 263.5" "Low region specificity" "Detected in single" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.58e-2)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (3.62e-1)" "unprognostic (1.29e-2)" "unprognostic (9.80e-3)" "unprognostic (1.78e-2)" "unprognostic (1.57e-2)" "unprognostic (8.51e-3)" "unprognostic (5.91e-2)" "unprognostic (8.99e-3)" "unprognostic (3.69e-1)" "unprognostic (1.29e-9)" "unprognostic (8.55e-3)" "unprognostic (1.54e-1)" "unprognostic (6.83e-3)" "unprognostic (1.97e-2)" 22.1 4.9 2.2 1.3 1.8 0.0 25.2 1.5 2.6 6.4 2.7 2.7 0.0 18.9 0.6 5.9 3.0 7.2 4.5 1.9 1.6 0.8 0.2 0.6 2.4 1.8 2.3 6.4 0.4 0.2 7.1 12.6 2.0 2.7 0.4 0.0 8.1 0.8 1.5 16.0 0.7 5.0 1.8 0.0 5.4 2.7 2.0 0.5 3.7 1.9 1.6 8.3 5.0 2.2 1.6 2.0 8.9 0.0 45.0 18.4 0.2 38.3 17.8 28.9 37.7 0.0 0.0 0.0 4.0 32.0 6.9 0.0 3.7 3.0 19.0 8.5 10.1 0.0 3.9 0.0 26.8 10.0 0.1 44.8 9.9 6.0 15.7 8.6 0.0 0.5 0.0 0.0 31.0 0.0 0.0 0.5 3.9 0.0 15.7 0.0 0.0 0.0 0.0 0.0 15.9 263.5 6.2 0.0 8.2 5.6 0.8 12.4 0.2 35.5 0.1 28.3 6.6 0.0 0.0 0.0 19.4 0.0 45.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.8 1.5 2.6 1.9 1.6 1.8 2.3 2.0 1.8 2.0 2.2 10.3 0.0 0.0 0.7 0.1 12.5 0.2 2.9 1.8 0.0 0.5 3.3 0.9 0.0 0.5 0.0 0.0 0.3 0.1 0.1 1.9 0.0 0.2 11.5 92.8 3.8 0.0 0.0 5.2 0.0 0.2 73.4 0.0 13.3 0.0 2.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 30.3 0.8 2.1 0.9 12.4 7.5 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.3 0.3 0.0 1.6 34.4 0.5 4.7 0.6 8.5 1.4 2.2 29.9 0.1 0.4 TWIST2 "bHLHa39, Dermo-1, DERMO1" ENSG00000233608 "Twist family bHLH transcription factor 2" Q8WVJ9 2 238848032-238910534 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 95.4;Fibroblasts: 58.9;Leydig cells: 48.1;Peritubular cells: 39.1;Theca cells: 23.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 24 "eosinophil: 4.6" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.6" "Cell line enhanced" "Detected in many" "ASC diff: 80.0;ASC TERT1: 50.5;BJ: 69.3;BJ hTERT+: 212.4;fHDF/TERT166: 97.4;U-2197: 81.3" "Low region specificity" "Detected in single" HPA062870 Supported Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Nucleoli "HPA062870: AB_2684888" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.83e-2)" "unprognostic (4.06e-2)" "unprognostic (1.13e-2)" "unprognostic (2.75e-2)" "unprognostic (2.33e-1)" "unprognostic (2.24e-1)" "unprognostic (1.17e-1)" "unprognostic (2.40e-9)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.98e-2)" "unprognostic (4.48e-2)" 59.7 4.0 0.3 1.4 0.3 0.4 43.3 0.3 0.5 83.0 0.6 22.9 0.3 31.3 0.7 10.1 30.4 1.7 10.8 0.4 0.3 1.8 0.7 9.3 0.3 0.4 0.8 39.9 1.8 0.1 8.3 3.1 0.4 25.7 1.1 0.0 7.9 3.7 1.8 33.5 8.9 2.9 0.4 2.3 10.3 1.9 0.3 0.1 8.2 1.0 0.4 21.3 54.2 0.5 0.1 4.5 0.4 0.0 80.0 50.5 0.1 69.3 212.4 31.0 46.4 0.0 0.0 0.0 2.1 97.4 2.5 0.5 0.7 5.4 22.5 0.0 7.3 0.0 4.0 0.2 13.7 0.0 1.6 11.8 2.9 15.0 12.5 3.7 4.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.7 0.0 0.9 11.8 1.2 2.2 81.3 0.8 0.0 0.0 0.0 0.3 2.1 4.3 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.4 0.3 0.4 0.8 0.4 0.4 0.3 0.5 2.5 0.0 2.6 0.0 0.1 2.0 16.0 0.0 7.4 0.0 0.5 0.4 0.6 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.4 3.6 95.4 1.3 0.0 0.0 4.4 0.0 1.9 58.9 0.0 2.1 1.3 0.5 2.9 0.1 2.2 0.0 0.2 0.0 0.0 0.0 3.6 1.2 48.1 0.8 1.8 12.2 0.4 0.0 8.2 0.5 0.1 0.1 0.0 39.1 0.0 20.5 0.0 0.0 0.0 0.0 0.0 1.1 9.6 0.5 3.3 0.2 1.7 1.6 1.6 23.2 0.0 3.7 TWNK "C10orf2, FLJ21832, IOSCA, PEO, PEO1, TWINKLE, TWINL" ENSG00000107815 "Twinkle mtDNA helicase" Q96RR1 10 100987367-100994403 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA replication" "Helicase, Hydrolase" "Deafness, Disease variant, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 6.8;Breast myoepithelial cells: 6.6;Ductal cells: 5.4;Endometrial stromal cells: 7.2;Granulosa cells: 7.1;Theca cells: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002532 Uncertain NA NA "Cluster 44: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "HPA002532: AB_1078311" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "unprognostic (1.16e-1)" "unprognostic (2.19e-2)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (7.82e-3)" "unprognostic (7.99e-2)" "unprognostic (1.22e-1)" "unprognostic (7.95e-2)" "unprognostic (7.52e-2)" "unprognostic (1.96e-2)" "unprognostic (9.46e-2)" "unprognostic (9.82e-3)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" "unprognostic (1.45e-1)" 4.9 7.0 3.7 5.5 3.7 3.0 7.5 3.6 3.5 3.8 3.2 4.4 3.3 4.6 5.3 5.5 6.6 2.6 5.0 3.4 3.6 5.9 6.0 2.1 6.1 3.9 4.0 5.1 5.2 4.8 2.4 3.8 3.8 4.0 4.8 1.6 4.0 3.4 11.6 5.5 3.8 4.5 3.7 4.6 3.9 8.3 4.0 8.1 4.1 12.6 8.3 6.6 3.5 3.5 15.5 32.0 12.5 39.7 11.1 7.2 14.7 11.4 14.8 17.3 16.6 52.6 13.1 55.4 21.1 7.0 10.4 25.0 52.2 27.7 21.1 25.5 31.0 42.1 17.4 40.2 19.1 54.8 16.7 14.9 30.7 25.5 77.6 15.8 10.6 26.3 45.9 15.0 12.3 21.2 37.0 18.8 35.8 28.2 25.9 35.5 27.5 33.2 10.7 15.4 20.1 38.5 12.0 16.0 37.8 13.8 20.9 16.0 12.4 8.6 17.4 10.6 32.5 28.0 31.3 46.0 10.6 47.8 9.8 1.2 0.6 0.1 1.2 0.5 3.7 2.4 1.8 2.7 1.2 2.1 2.0 2.2 0.0 2.5 0.8 1.3 0.4 1.4 3.7 3.7 3.6 3.5 3.4 3.6 3.9 4.0 3.8 3.7 4.0 3.5 3.5 0.0 2.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 6.8 6.6 0.0 0.0 3.1 1.8 0.0 4.2 1.9 0.0 3.9 5.4 0.0 2.3 7.2 2.0 0.0 0.0 0.0 3.0 3.7 1.3 0.0 2.8 1.3 7.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.4 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.6 1.1 9.1 0.0 0.0 TXNL4A "DIB1, DIM1, HsT161, SNRNP15, TXNL4, U5-15kD" ENSG00000141759 "Thioredoxin like 4A" P83876 18 79970813-80033949 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, mRNA processing, mRNA splicing" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 360.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041324 Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear membrane" Cytosol "HPA041324: AB_2677410" "unprognostic (7.56e-2)" "unprognostic (1.06e-3)" "unprognostic (5.94e-2)" "unprognostic (2.67e-2)" "unprognostic (6.99e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.45e-1)" "unprognostic (9.39e-2)" "unprognostic (3.31e-3)" "unprognostic (7.61e-2)" "unprognostic (4.94e-2)" "unprognostic (3.11e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" 61.1 79.1 88.1 39.9 92.5 59.6 52.1 96.0 98.7 37.2 94.9 53.5 32.8 35.7 50.3 69.4 38.1 24.1 88.6 95.0 98.4 87.7 97.1 48.2 53.4 89.4 95.8 32.6 86.0 42.2 95.5 31.6 94.1 53.9 33.2 36.5 55.0 25.3 88.5 59.3 48.0 25.6 93.1 67.8 60.5 88.0 91.6 52.4 51.1 61.3 45.6 46.1 45.5 99.3 98.5 129.3 113.0 108.1 90.3 94.7 99.8 104.3 83.5 138.7 124.9 121.2 68.0 118.8 37.8 100.3 94.1 81.4 137.1 121.5 91.2 139.7 173.7 85.6 196.1 288.7 115.4 247.6 134.1 88.6 105.5 98.7 125.6 87.9 132.4 145.0 76.2 168.0 97.8 177.1 177.0 166.3 88.6 74.3 276.9 106.2 75.7 245.4 137.7 152.7 172.1 125.0 51.6 151.8 200.5 96.9 74.6 145.0 62.9 121.3 149.5 55.7 129.4 74.0 302.3 198.6 113.4 185.7 113.9 10.6 10.3 9.0 14.7 12.7 9.9 15.8 11.8 11.6 14.5 17.6 11.7 14.0 8.2 15.6 13.1 31.3 17.3 6.1 88.1 92.5 96.0 98.7 95.0 98.4 89.4 95.8 94.1 93.1 91.6 99.3 81.0 19.2 42.6 14.0 89.2 87.2 76.9 73.6 64.3 35.7 131.9 139.7 80.3 65.8 62.3 66.2 35.5 107.8 104.8 53.6 360.0 123.4 259.3 98.5 66.0 65.2 56.3 94.1 25.3 125.2 156.9 69.8 71.4 88.1 11.4 84.1 47.2 97.4 126.0 45.4 22.5 88.4 59.0 66.4 76.9 245.5 42.0 89.5 94.3 14.0 87.2 81.5 60.8 21.1 34.8 144.5 54.9 45.1 177.9 177.2 48.6 271.8 41.9 51.3 46.0 61.2 100.8 84.6 74.2 147.6 109.8 96.7 78.7 112.6 71.1 119.4 UBR1 ENSG00000159459 "Ubiquitin protein ligase E3 component n-recognin 1" Q8IWV7 15 42942897-43106113 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 108.9;Inhibitory neurons: 108.8;Oligodendrocyte precursor cells: 102.1;Oligodendrocytes: 127.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038838, HPA038839" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Vesicles "Nucleoplasm, Cytosol" "HPA038838: AB_10673120, HPA038839: " "unprognostic (1.07e-2)" "unprognostic (5.02e-2)" "unprognostic (9.77e-2)" "unprognostic (1.55e-2)" "unprognostic (1.89e-2)" "unprognostic (1.29e-1)" "unprognostic (2.67e-1)" "unprognostic (1.49e-1)" "unprognostic (4.79e-1)" "unprognostic (2.97e-2)" "unprognostic (1.93e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-3)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" 9.1 7.9 12.5 8.8 29.4 24.9 9.3 11.7 17.4 9.9 4.8 8.6 7.8 10.7 7.4 5.8 8.0 8.6 13.7 11.6 31.5 9.2 7.1 8.6 10.9 24.2 18.3 7.7 9.5 14.3 6.6 10.5 21.6 10.0 8.0 14.3 6.3 10.5 12.0 5.6 7.8 9.6 8.5 9.5 7.2 10.1 21.2 13.3 12.6 14.0 8.7 9.1 5.8 48.6 7.4 10.2 11.6 9.6 17.1 14.7 10.7 17.6 19.4 15.9 19.2 13.3 5.5 8.6 10.1 18.4 18.9 12.4 17.1 15.5 18.1 18.0 8.4 33.1 20.4 6.3 12.3 23.0 14.4 15.3 8.4 18.8 14.8 14.6 17.0 16.7 19.6 12.3 18.7 4.5 12.7 6.8 6.5 18.9 10.6 16.4 15.7 6.4 14.9 16.6 12.0 10.3 22.7 12.0 7.7 13.1 10.9 12.2 24.3 17.9 11.1 16.7 18.0 14.6 26.4 23.6 12.2 14.6 16.6 3.7 1.5 2.5 2.4 1.8 2.9 1.9 2.6 2.9 1.4 2.3 2.6 3.2 2.9 3.2 1.7 2.2 1.9 0.9 12.5 29.4 11.7 17.4 11.6 31.5 24.2 18.3 21.6 8.5 21.2 48.6 46.4 48.1 30.7 73.1 28.9 10.6 11.6 9.3 17.1 27.5 15.4 10.8 28.0 12.8 19.1 9.2 27.1 14.7 35.8 12.8 0.0 10.8 16.8 13.4 27.4 24.5 14.4 23.8 108.9 14.4 7.7 25.6 20.9 18.2 28.5 22.8 17.2 9.9 8.1 32.0 108.8 10.9 14.2 16.4 10.6 16.9 16.1 17.1 8.8 73.1 15.6 13.5 23.7 102.1 127.6 10.3 8.2 20.7 33.2 7.7 12.3 9.2 15.7 38.8 13.1 34.7 36.5 27.0 17.8 8.6 7.2 36.9 31.4 16.5 10.6 9.8 UFSP2 "C4orf20, FLJ11200" ENSG00000109775 "UFM1 specific peptidase 2" Q9NUQ7 4 185399537-185425979 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 190.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039985, HPA043298" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA039985: AB_10794206, HPA043298: AB_10795037" "unprognostic (8.87e-2)" "unprognostic (1.85e-2)" "unprognostic (1.52e-1)" "unprognostic (1.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" "unprognostic (3.63e-2)" "unprognostic (3.19e-2)" "unprognostic (3.69e-1)" "unprognostic (1.50e-1)" "unprognostic (2.04e-2)" "unprognostic (2.56e-1)" "prognostic favorable (1.07e-8)" "unprognostic (1.92e-1)" "unprognostic (8.12e-2)" "unprognostic (9.36e-3)" "unprognostic (6.70e-3)" 21.2 24.9 19.9 9.5 21.7 5.7 24.3 25.2 24.1 21.6 29.6 19.5 13.0 19.9 28.1 25.8 17.7 15.6 32.1 20.4 21.9 37.3 24.1 17.1 11.9 20.4 20.2 31.4 19.7 23.8 10.0 14.0 20.9 19.8 15.3 56.4 20.3 19.2 48.5 21.6 12.0 20.2 20.7 14.5 17.5 21.0 21.3 14.3 25.9 40.6 16.1 16.2 10.1 25.3 17.5 11.9 28.8 24.3 25.8 25.6 15.3 20.3 20.5 19.3 19.3 18.4 23.2 17.9 9.0 19.7 14.7 16.1 20.4 32.2 17.4 21.8 12.4 11.8 13.0 23.3 30.2 15.3 12.3 14.7 26.8 16.5 16.7 26.7 35.7 21.9 24.8 34.3 28.2 16.3 22.0 16.4 8.7 11.8 16.7 20.2 11.5 20.4 31.9 11.4 18.6 14.8 11.3 25.6 23.1 17.6 15.4 13.6 27.3 9.5 16.8 7.5 17.2 34.6 14.8 9.5 30.5 11.0 25.3 10.8 12.3 7.6 21.2 10.4 25.7 22.0 21.7 24.1 14.1 15.4 23.2 22.9 0.7 21.5 11.1 19.9 20.6 12.5 19.9 21.7 25.2 24.1 20.4 21.9 20.4 20.2 20.9 20.7 21.3 25.3 33.8 6.4 23.9 14.7 30.1 22.0 28.7 35.1 33.0 47.6 20.9 25.5 27.0 15.7 31.1 20.2 66.7 26.0 23.4 8.3 111.6 28.3 190.5 16.4 28.9 24.1 19.3 24.0 12.2 33.1 29.7 34.2 20.4 19.2 29.7 21.9 21.8 17.3 27.2 18.5 17.8 18.6 28.5 22.1 18.8 52.9 35.4 18.5 35.6 12.2 17.3 71.8 21.6 23.6 33.2 19.7 14.6 42.2 53.0 15.4 22.2 100.9 23.7 87.9 65.7 31.8 38.9 89.3 56.7 22.6 18.9 41.9 27.1 35.6 14.8 19.6 UMOD ENSG00000169344 Uromodulin P07911 16 20333051-20356301 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 693 "kidney: 2277.8" "Group enriched" "Detected in some" 146 "Collecting duct cells: 248.3;Distal tubular cells: 950.9" "Cancer enriched" "Detected in single" 39 "renal cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009446, HPA043420, HPA054721" Enhanced "Secreted in other tissues" NA NA 55000000 66000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 39: Non-specific - Basic cellular processes" "CAB009446: AB_2212378, HPA043420: AB_2678474, HPA054721: AB_2682585" "unprognostic (2.51e-2)" "unprognostic (1.33e-1)" "unprognostic (6.45e-2)" "unprognostic (3.02e-2)" "unprognostic (1.49e-2)" "unprognostic (1.43e-1)" 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2277.8 0.8 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 248.3 0.0 0.0 0.0 0.0 950.9 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UNC80 "C2orf21, FLJ33496, KIAA1843, UNC-80" ENSG00000144406 "Unc-80 homolog, NALCN channel complex subunit" Q8N2C7 2 209771832-209999300 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.0;pituitary gland: 13.6;retina: 18.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 117.7;Excitatory neurons: 432.0;Inhibitory neurons: 354.7;Oligodendrocyte precursor cells: 290.5" "Cancer enhanced" "Detected in some" "glioma: 0.8;prostate cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 2.5;SCLC-21H: 4.0;SH-SY5Y: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042472, HPA050959" Enhanced Approved "Nuclear bodies,Vesicles" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear bodies" Vesicles "HPA042472: AB_10965318, HPA050959: " "unprognostic (7.91e-3)" "unprognostic (2.25e-4)" "unprognostic (1.44e-2)" "unprognostic (3.20e-4)" "unprognostic (1.92e-1)" "unprognostic (3.40e-2)" "unprognostic (3.31e-3)" "unprognostic (5.36e-2)" "unprognostic (5.16e-1)" "unprognostic (7.85e-2)" "unprognostic (5.24e-3)" "unprognostic (8.94e-2)" "unprognostic (1.50e-2)" "unprognostic (1.51e-2)" "unprognostic (6.50e-2)" "unprognostic (1.95e-1)" "unprognostic (7.40e-3)" 0.0 3.9 6.4 0.0 9.9 0.0 0.0 15.6 21.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.4 1.1 0.0 6.9 4.9 0.1 0.0 0.1 0.0 6.7 1.5 0.5 1.0 0.2 13.6 0.0 5.8 0.9 0.1 18.9 0.1 0.2 0.0 0.1 0.1 0.2 1.1 0.2 0.4 3.5 2.6 0.1 0.3 0.0 0.0 0.2 0.0 5.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 4.0 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 9.9 15.6 21.0 6.9 4.9 6.7 1.5 5.8 1.1 2.6 5.0 0.2 0.0 1.1 49.0 0.0 0.8 0.3 1.9 0.0 117.7 0.2 0.1 2.1 0.0 0.7 0.0 66.7 0.0 0.0 0.0 0.0 0.0 31.9 1.1 1.7 0.5 0.0 0.0 432.0 0.0 0.0 1.1 0.0 0.1 1.3 0.6 0.0 0.0 0.1 52.2 354.7 0.0 0.0 0.0 0.0 10.5 0.9 0.3 0.0 10.3 0.0 26.6 0.0 290.5 12.8 0.1 0.0 1.9 0.0 1.2 0.0 0.2 0.8 75.6 0.0 0.2 0.1 7.5 3.8 0.0 0.1 0.0 0.0 15.1 0.0 0.3 VANGL1 STB2 ENSG00000173218 "VANGL planar cell polarity protein 1" Q8TAA9 1 115641970-115698224 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 6.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.3;NK-cells: 6.2;T-cells: 3.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025235, CAB076375" Approved Approved "Plasma membrane" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB076375: AB_2665604, HPA025235: AB_1858718" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "prognostic favorable (7.53e-4)" "unprognostic (9.94e-2)" "unprognostic (1.71e-2)" "unprognostic (5.18e-2)" "unprognostic (2.18e-3)" "unprognostic (5.11e-3)" "unprognostic (2.11e-1)" "unprognostic (6.43e-3)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.88e-2)" "unprognostic (1.74e-2)" "unprognostic (7.71e-3)" "unprognostic (1.21e-1)" "unprognostic (4.50e-3)" "unprognostic (9.06e-3)" 4.9 3.9 2.1 3.8 1.2 2.5 3.2 0.8 1.1 9.1 3.0 6.8 3.8 5.5 4.9 10.4 12.0 3.8 5.4 1.3 1.3 5.3 3.0 4.1 2.1 1.2 3.0 4.4 5.0 5.2 0.5 3.6 1.7 4.4 6.4 1.6 6.4 4.5 0.9 6.8 3.9 7.3 1.2 2.2 5.5 5.0 6.5 7.3 7.6 2.4 2.5 6.4 4.4 1.0 49.6 20.7 6.6 8.9 24.1 21.5 13.1 18.8 13.5 24.1 19.1 12.0 24.1 0.0 31.5 21.9 22.7 60.9 11.2 33.3 15.8 57.9 13.7 27.4 18.4 9.8 8.8 8.2 11.4 11.4 23.1 17.2 18.2 12.8 24.1 45.9 16.8 14.8 24.5 65.7 41.0 3.4 16.7 28.8 19.5 0.1 19.1 14.3 11.0 32.8 5.9 8.0 33.9 22.2 15.4 12.4 11.3 8.8 26.2 16.5 25.7 36.3 34.6 2.1 2.3 0.2 22.3 14.3 41.1 0.0 0.5 0.0 1.9 0.3 0.5 0.2 1.2 1.9 2.3 0.0 0.4 2.0 0.0 6.2 0.5 2.0 3.0 1.0 2.1 1.2 0.8 1.1 1.3 1.3 1.2 3.0 1.7 1.2 6.5 1.0 9.2 3.2 3.2 5.5 0.5 7.4 7.4 16.8 11.4 5.2 4.6 4.6 7.9 2.8 9.6 9.2 39.6 5.0 3.4 11.2 0.0 15.7 6.1 25.1 7.7 10.5 6.7 13.2 0.9 13.8 7.3 10.1 8.2 17.0 0.0 5.1 28.9 2.5 4.3 0.0 0.7 8.6 10.2 1.9 1.4 3.0 5.9 2.9 0.0 4.7 11.1 4.7 9.2 2.0 0.1 20.8 6.1 8.2 1.8 8.3 2.6 5.6 12.8 0.9 6.6 4.3 8.5 5.5 7.0 20.0 6.5 0.4 3.1 3.2 10.3 6.5 VAX1 ENSG00000148704 "Ventral anterior homeobox 1" Q5SQQ9 10 117128521-117138301 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "brain: 8.4" "Cell type enriched" "Detected in some" 4 "Inhibitory neurons: 7.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 3.1;WM-115: 2.3" "Group enriched" "Detected in some" 6 "basal ganglia: 5.6;hypothalamus: 3.2;olfactory bulb: 1.5" "Low region specificity" "Detected in some" HPA028946 Uncertain Approved "Nucleoplasm,Nucleoli rim" Yes NA "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli rim" Nucleoplasm "HPA028946: AB_10602679" "unprognostic (1.08e-2)" "unprognostic (1.92e-2)" "unprognostic (1.46e-1)" "unprognostic (2.96e-2)" "unprognostic (5.77e-3)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (5.72e-2)" "unprognostic (2.09e-1)" "unprognostic (2.99e-1)" 0.0 0.0 1.6 0.0 4.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 8.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.3 0.0 0.0 0.0 0.0 0.0 0.0 2.8 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 4.4 0.0 2.8 0.2 8.4 0.1 0.2 0.0 0.0 2.3 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VEGFC "VEGF-C, VRP" ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792922 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 39.3;Endothelial cells: 22.0;Leydig cells: 13.7;Microglial cells: 36.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 146.5;HBF TERT88: 114.4;hTEC/SVTERT24-B: 116.5;LHCN-M2: 129.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 7.0" "Secreted to blood" NA NA 383000 340000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (4.18e-1)" "unprognostic (4.07e-2)" "unprognostic (4.84e-3)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (3.05e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (4.53e-1)" "unprognostic (2.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.89e-3)" "unprognostic (4.41e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" 25.0 6.9 2.6 4.2 2.5 0.2 16.7 2.7 2.8 9.7 2.1 4.7 2.4 7.3 1.8 4.0 8.5 6.8 12.7 2.4 2.4 6.7 4.2 16.8 8.0 3.1 2.8 5.9 1.8 2.7 1.5 19.3 2.9 5.1 3.3 1.2 7.4 5.0 3.1 5.1 6.8 6.6 2.6 3.9 3.2 1.4 3.7 1.1 27.7 4.1 3.4 10.3 7.6 2.5 5.9 2.8 1.8 0.0 25.5 25.3 0.0 146.5 87.3 79.2 62.5 0.0 0.7 0.0 0.0 82.7 33.1 4.4 1.3 54.8 114.4 0.1 2.8 0.0 3.8 0.0 13.9 0.0 0.0 27.0 2.5 116.5 80.5 79.3 49.7 0.0 0.0 0.0 129.9 2.1 0.0 0.0 1.3 0.0 47.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 2.3 3.3 0.1 0.7 0.7 0.2 24.2 83.6 9.2 20.8 42.1 0.2 0.0 0.0 34.9 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 2.5 2.7 2.8 2.4 2.4 3.1 2.8 2.9 2.6 3.7 2.5 39.3 3.2 0.0 10.1 0.1 2.4 1.3 3.2 0.0 1.0 3.2 1.7 1.5 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.5 3.1 8.3 10.9 22.0 0.0 0.0 2.0 0.0 0.0 9.1 0.0 11.0 0.0 8.5 10.0 0.0 0.3 1.7 2.0 0.0 4.1 0.3 2.2 1.2 13.7 0.4 3.6 36.5 0.0 3.4 0.0 1.5 0.6 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.2 0.0 1.9 11.7 0.2 2.0 0.3 2.0 0.0 0.2 1.9 0.0 3.6 VHL VHL1 ENSG00000134086 "Von Hippel-Lindau tumor suppressor" P40337 3 10141778-10153667 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Congenital erythrocytosis, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 146.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031631, HPA031632, HPA068954" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA031631: AB_2673968, HPA031632: AB_2673969, HPA068954: " "prognostic unfavorable (9.02e-5)" "unprognostic (1.10e-1)" "unprognostic (4.46e-3)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (3.55e-1)" "unprognostic (3.03e-2)" "unprognostic (4.36e-2)" "unprognostic (5.82e-3)" "unprognostic (1.81e-2)" "unprognostic (2.51e-1)" "prognostic favorable (7.84e-4)" "unprognostic (1.46e-1)" "unprognostic (2.92e-2)" "unprognostic (1.28e-3)" 14.0 13.7 11.5 21.1 11.0 27.9 14.7 13.6 12.1 11.8 6.7 14.8 15.7 14.1 9.8 12.3 13.4 11.5 7.9 11.8 14.9 12.6 14.1 11.8 29.6 9.4 9.4 12.6 12.7 11.7 9.0 14.1 9.3 14.0 15.7 8.9 14.5 10.2 11.4 14.2 17.2 12.8 9.6 22.5 16.0 13.4 16.6 23.4 15.8 7.7 29.7 12.5 10.9 12.5 19.5 18.2 39.9 24.6 36.0 27.7 146.5 16.8 24.0 21.1 24.5 21.5 23.7 67.9 22.2 23.0 29.9 16.4 37.2 23.6 25.7 33.0 33.7 52.7 30.5 30.6 34.3 47.3 41.3 28.1 26.3 28.0 35.1 28.4 24.6 42.5 48.3 50.3 21.1 35.0 45.5 40.9 26.7 21.1 23.4 57.3 34.6 34.6 25.5 48.7 15.0 49.4 35.0 18.7 21.0 23.9 37.0 59.1 21.3 20.8 27.7 19.6 26.8 35.7 78.1 105.6 23.2 55.3 19.4 4.6 3.2 2.3 2.6 2.2 1.9 2.5 1.8 2.2 2.0 3.3 1.7 1.8 5.6 3.0 2.0 2.3 1.7 1.2 11.5 11.0 13.6 12.1 11.8 14.9 9.4 9.4 9.3 9.6 16.6 12.5 12.4 12.8 12.5 9.1 38.7 14.7 17.8 14.3 24.5 14.7 10.7 6.1 6.1 20.0 9.6 16.5 18.8 16.8 21.9 10.7 7.9 11.8 9.6 13.1 26.1 14.8 14.4 30.5 15.9 5.1 18.7 12.8 20.9 19.9 5.1 18.4 18.9 14.3 14.9 18.5 14.2 11.3 16.2 27.1 45.8 7.3 14.0 32.3 12.4 7.5 31.9 9.1 28.8 12.1 14.9 10.7 11.7 11.3 33.3 23.8 12.3 9.5 9.7 15.3 6.6 17.4 11.9 15.4 24.0 26.7 20.5 17.2 23.5 21.4 10.2 25.9 VIPAS39 "C14orf133, hSPE-39, SPE-39, SPE39, VIPAR, VPS16B" ENSG00000151445 "VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog" Q9H9C1 14 77426675-77457952 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Protein transport, Spermatogenesis, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003589, HPA003593" Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA003589: AB_10599707, HPA003593: AB_10601879" "unprognostic (1.30e-1)" "unprognostic (7.56e-2)" "unprognostic (3.41e-2)" "unprognostic (1.04e-1)" "unprognostic (5.79e-3)" "unprognostic (5.76e-2)" "prognostic unfavorable (1.06e-6)" "unprognostic (2.53e-2)" "unprognostic (1.67e-1)" "unprognostic (5.77e-2)" "unprognostic (1.57e-1)" "unprognostic (1.36e-1)" "unprognostic (1.56e-3)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (5.91e-2)" "unprognostic (1.09e-2)" 12.4 11.8 15.3 9.4 16.0 9.1 12.2 15.4 17.9 12.1 15.6 14.3 10.1 12.1 14.7 13.2 10.8 9.1 14.8 15.7 15.6 11.2 13.6 9.9 12.4 15.2 15.3 18.5 11.9 14.6 13.4 15.5 15.6 11.8 12.7 14.4 10.0 13.7 13.7 13.7 11.1 14.6 15.6 13.2 11.6 15.9 15.9 16.5 11.7 15.0 14.7 13.9 11.6 17.7 10.6 17.8 18.3 26.6 32.5 26.5 18.3 17.5 16.1 20.8 20.2 11.9 24.7 18.4 15.1 14.3 10.8 20.4 17.0 15.5 24.9 15.8 5.8 13.7 10.7 14.7 26.3 8.6 23.2 25.4 24.2 17.8 24.2 27.7 36.3 25.5 10.9 17.4 19.9 25.1 17.7 18.4 16.5 31.0 19.3 17.6 23.0 12.7 20.9 15.3 13.0 15.0 22.7 16.7 20.2 21.7 39.1 18.1 25.9 14.1 12.5 15.5 9.8 14.8 15.1 14.6 15.3 15.9 17.0 1.8 9.4 17.6 5.0 15.6 6.5 4.8 6.5 5.6 10.8 5.6 5.7 5.6 7.8 13.0 20.3 5.5 7.8 6.1 15.3 16.0 15.4 17.9 15.7 15.6 15.2 15.3 15.6 15.6 15.9 17.7 6.0 3.2 1.5 16.0 6.3 3.2 3.0 4.7 2.8 8.5 5.3 5.3 9.0 4.3 3.4 9.2 20.9 20.7 6.3 7.2 7.9 9.3 5.7 4.0 7.4 6.8 5.4 11.2 14.6 6.3 16.6 8.2 5.1 6.2 2.5 12.2 8.2 6.6 13.3 10.1 14.4 5.4 2.0 17.6 3.8 3.8 11.5 8.3 0.0 13.1 17.6 7.4 9.2 15.1 17.2 9.1 9.4 15.4 4.0 2.5 10.7 5.8 3.6 13.3 6.6 5.5 6.8 11.0 9.2 6.3 4.3 19.2 6.3 15.5 7.2 2.8 VPS13B "CHS1, COH1" ENSG00000132549 "Vacuolar protein sorting 13 homolog B" Q7Z7G8 8 99013266-99877580 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 160.9;Excitatory neurons: 235.2;Inhibitory neurons: 253.2;Microglial cells: 204.2;Oligodendrocyte precursor cells: 217.1;Oligodendrocytes: 238.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043865 Approved "Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "HPA043865: AB_2678704" "unprognostic (4.23e-2)" "unprognostic (1.98e-2)" "unprognostic (1.02e-1)" "unprognostic (3.60e-3)" "unprognostic (5.72e-2)" "unprognostic (6.08e-3)" "unprognostic (1.95e-1)" "unprognostic (1.62e-1)" "unprognostic (1.94e-1)" "unprognostic (1.65e-3)" "unprognostic (8.60e-2)" "unprognostic (5.95e-2)" "unprognostic (6.52e-2)" "unprognostic (5.19e-2)" "unprognostic (1.59e-1)" "unprognostic (8.93e-3)" "unprognostic (2.90e-1)" 4.0 3.0 2.4 4.4 3.3 13.4 4.7 4.5 3.0 5.4 8.2 3.6 2.3 7.2 3.8 4.4 4.9 4.4 2.3 2.0 1.9 3.8 3.1 3.5 4.8 3.6 2.4 8.1 3.4 6.8 2.3 4.0 3.6 4.9 3.7 6.0 3.2 4.1 2.9 4.0 3.0 5.4 2.2 4.2 3.6 4.9 4.9 7.1 4.7 4.4 5.0 4.5 3.7 5.3 8.6 6.1 7.2 5.3 13.3 15.9 3.6 5.4 9.9 5.3 7.0 3.6 4.3 4.8 6.9 9.3 3.9 3.9 5.0 5.0 9.6 7.7 4.6 10.3 6.5 2.8 4.3 5.0 7.4 10.3 4.6 8.5 12.2 7.4 7.6 7.9 7.9 12.4 6.1 5.3 10.5 2.9 2.3 8.9 2.2 8.3 5.1 9.1 3.5 8.0 2.1 6.0 8.4 4.0 4.0 6.4 7.2 5.6 10.8 7.9 7.4 7.1 4.6 5.0 6.2 12.7 6.0 7.9 5.6 3.0 1.2 2.8 1.2 1.0 1.1 3.3 1.0 0.9 0.5 1.6 1.7 1.1 6.1 0.7 2.3 0.6 1.4 0.5 2.4 3.3 4.5 3.0 2.0 1.9 3.6 2.4 3.6 2.2 4.9 5.3 15.5 19.2 12.2 160.9 24.2 8.8 7.6 9.2 15.4 15.1 8.9 7.6 12.8 10.0 11.9 3.7 37.5 4.9 21.6 7.3 0.0 4.9 8.6 10.9 42.7 11.5 9.0 22.9 235.2 4.6 4.0 18.2 28.1 12.7 3.8 10.4 6.4 5.2 6.5 11.8 253.2 11.9 8.2 15.6 11.3 9.6 27.7 17.8 7.2 204.2 15.0 9.4 17.5 217.1 238.1 4.0 11.0 20.7 19.2 6.2 9.8 2.9 8.2 12.9 0.0 15.7 14.7 23.9 7.3 13.0 9.7 4.2 19.5 14.6 7.4 5.7 VPS33B FLJ14848 ENSG00000184056 "VPS33B late endosome and lysosome associated" Q9H267 15 90998673-91022603 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA040415 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA040415: AB_10795419" "unprognostic (7.49e-2)" "unprognostic (1.40e-1)" "unprognostic (1.15e-1)" "unprognostic (2.55e-2)" "unprognostic (3.06e-1)" "unprognostic (1.79e-2)" "unprognostic (2.97e-2)" "unprognostic (2.42e-2)" "unprognostic (1.30e-1)" "unprognostic (2.84e-3)" "unprognostic (2.78e-2)" "unprognostic (7.94e-2)" "unprognostic (3.70e-1)" "unprognostic (6.75e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-2)" "unprognostic (1.00e-2)" 5.7 5.4 5.9 5.1 7.2 2.8 6.1 6.3 7.6 6.6 6.7 6.7 5.8 6.3 7.0 6.8 8.1 4.7 3.8 6.6 7.1 5.9 4.3 5.6 6.9 6.3 6.3 6.8 6.9 8.1 5.3 6.8 6.4 6.6 6.4 5.8 6.7 6.7 4.1 11.0 6.9 6.2 6.3 6.9 7.9 6.1 7.2 5.4 5.5 4.3 6.5 6.1 6.4 7.7 5.6 16.4 3.4 6.0 8.9 15.1 17.7 6.8 12.7 10.7 10.9 7.0 11.0 7.1 9.4 11.9 9.6 10.0 4.7 10.3 5.6 3.8 4.9 7.7 6.6 10.3 10.9 9.6 10.3 17.0 10.7 8.0 9.5 9.3 15.2 8.6 12.6 1.7 7.9 11.9 6.5 6.8 8.3 14.8 5.8 4.9 8.9 8.7 12.2 12.3 5.2 9.6 10.0 7.9 17.5 8.1 8.1 12.6 10.4 7.0 7.8 5.0 5.2 3.6 12.9 2.7 14.7 9.3 6.4 12.5 7.1 12.1 7.7 11.8 8.9 5.6 6.8 6.9 9.5 7.8 7.8 11.0 3.2 7.9 13.4 4.7 5.9 6.4 5.9 7.2 6.3 7.6 6.6 7.1 6.3 6.3 6.4 6.3 7.2 7.7 2.2 0.0 7.3 5.5 5.3 2.2 3.0 3.5 1.8 9.2 2.6 1.8 4.8 2.8 4.4 3.7 2.1 16.8 5.0 6.9 5.9 9.0 3.1 3.0 2.7 4.7 2.4 5.7 11.4 9.4 10.8 2.9 7.7 2.9 8.2 6.7 5.7 4.9 8.0 8.4 11.3 5.1 4.1 6.0 4.1 4.0 3.7 4.5 8.8 3.7 7.7 6.3 3.1 7.5 9.7 9.3 5.0 5.3 4.9 4.1 7.9 4.3 7.9 7.0 6.6 2.7 3.5 11.0 8.2 2.3 2.6 12.3 5.0 3.6 4.3 3.0 VPS53 "FLJ10979, HCCS1" ENSG00000141252 "VPS53 subunit of GARP complex" Q5VIR6 17 508503-721717 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 270.0;Late spermatids: 203.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022988, HPA024446" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" Cytosol "HPA022988: AB_1848679, HPA024446: AB_1848680" "unprognostic (8.62e-3)" "unprognostic (7.98e-2)" "unprognostic (2.09e-1)" "prognostic favorable (1.08e-5)" "unprognostic (1.39e-2)" "unprognostic (9.08e-3)" "unprognostic (3.12e-1)" "unprognostic (9.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.53e-2)" "unprognostic (1.82e-2)" "unprognostic (1.89e-2)" "unprognostic (2.81e-1)" "unprognostic (4.82e-2)" "unprognostic (1.31e-1)" 4.3 4.7 7.0 3.0 5.9 20.5 4.6 21.4 10.3 5.2 2.8 4.5 3.7 4.4 3.4 9.0 4.0 3.6 4.3 8.2 3.3 4.0 4.5 5.1 4.9 3.0 3.9 5.3 4.5 6.4 6.0 4.6 4.2 4.6 5.9 8.1 4.7 5.0 7.0 7.1 4.0 6.1 0.9 4.5 5.0 14.6 4.0 4.9 7.6 5.1 5.2 4.1 4.8 9.4 12.9 26.5 7.6 8.3 12.4 9.5 5.5 6.4 9.4 15.8 15.4 12.6 5.8 7.8 5.9 19.9 10.0 10.9 16.5 13.9 23.1 6.7 11.4 5.0 17.2 8.1 6.1 6.6 9.2 11.1 7.8 14.7 9.8 6.4 11.7 9.7 9.1 9.1 14.9 8.9 4.3 5.1 6.2 5.6 6.9 10.5 3.9 5.2 8.0 10.4 7.6 6.1 12.4 4.3 5.4 7.5 6.5 3.5 7.9 6.8 5.4 12.5 7.0 4.3 3.3 4.8 11.5 5.2 8.6 8.1 1.9 4.4 2.4 2.3 1.8 2.1 2.2 1.7 1.1 3.0 2.3 1.9 6.1 1.9 5.6 3.0 1.9 0.9 7.0 5.9 21.4 10.3 8.2 3.3 3.0 3.9 4.2 0.9 4.0 9.4 16.0 12.8 25.9 54.5 19.3 25.5 16.5 11.6 19.9 53.3 19.6 9.3 17.4 14.3 21.5 40.5 70.9 10.5 19.9 24.9 1.9 16.7 270.0 23.9 22.2 18.7 24.6 5.0 109.3 18.3 7.9 18.5 26.5 28.1 24.1 18.2 15.7 17.7 21.4 63.9 103.6 27.4 4.1 20.6 19.4 203.9 18.6 21.0 10.6 39.4 27.5 18.3 37.0 48.2 62.5 25.3 15.5 23.0 20.6 18.7 21.0 10.6 24.3 52.2 6.6 31.1 20.7 46.0 35.3 24.6 38.8 8.9 26.8 17.2 22.0 19.6 VRK1 ENSG00000100749 "VRK serine/threonine kinase 1" Q99986 14 96797304-96954846 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.4;testis: 37.1" "Cell type enhanced" "Detected in all" "Spermatocytes: 198.9;Spermatogonia: 110.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000660, HPA017929" Enhanced Supported Nucleoplasm,Cytosol Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA000660: AB_1080579, HPA017929: AB_1858770" "unprognostic (1.03e-1)" "unprognostic (1.17e-2)" "unprognostic (1.84e-2)" "unprognostic (2.24e-3)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (4.20e-2)" "unprognostic (2.11e-2)" "unprognostic (5.47e-2)" "unprognostic (5.14e-2)" "unprognostic (1.60e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (4.56e-2)" "unprognostic (3.36e-2)" "unprognostic (1.58e-1)" 5.9 5.2 5.9 12.8 7.1 50.4 11.5 6.0 7.9 5.2 4.3 10.8 6.5 6.5 6.9 8.9 9.2 4.4 5.2 5.9 5.1 4.9 5.5 4.9 27.1 5.3 5.5 6.0 3.2 5.4 3.1 7.6 5.4 5.0 12.3 4.4 4.3 5.0 4.7 7.4 7.2 6.7 4.8 11.3 6.5 37.1 5.9 35.5 5.9 4.6 27.9 7.7 5.4 7.0 52.4 27.0 78.5 30.2 9.2 14.9 44.8 42.8 34.4 67.1 65.4 36.0 54.7 139.2 22.4 24.3 39.2 56.5 75.5 54.4 90.5 73.4 36.4 90.5 18.7 39.3 10.2 168.5 49.2 8.5 9.7 50.4 32.6 12.8 47.0 104.8 76.6 79.0 56.9 65.5 137.1 76.5 47.8 39.9 59.3 124.5 134.2 48.6 32.3 59.3 53.2 28.0 34.2 36.4 30.8 36.0 39.3 66.6 24.4 27.9 22.8 47.7 37.3 37.7 53.5 124.8 44.7 74.6 34.8 42.7 12.3 26.2 21.5 15.5 29.0 31.3 24.9 26.4 15.7 32.7 27.1 27.3 6.5 45.6 15.2 21.4 34.9 19.4 5.9 7.1 6.0 7.9 5.9 5.1 5.3 5.5 5.4 4.8 5.9 7.0 15.3 3.2 4.6 6.8 30.6 16.8 13.8 23.3 6.2 12.4 9.3 11.3 11.8 12.8 16.7 14.7 8.4 34.8 24.8 6.3 11.7 13.5 21.3 21.1 8.3 12.4 3.0 76.2 42.0 19.4 48.3 11.4 14.8 10.8 28.5 20.0 7.1 3.3 19.2 10.1 36.2 10.4 20.3 11.8 14.9 11.5 5.6 12.0 12.4 19.7 14.2 6.2 27.8 12.1 19.8 10.3 2.2 9.8 25.4 6.1 3.0 11.2 37.6 9.6 19.7 14.3 15.1 198.9 110.9 14.1 13.9 15.1 26.8 9.2 18.1 10.4 VSX2 "CHX10, HOX10, RET1" ENSG00000119614 "Visual system homeobox 2" P58304 14 74239449-74262738 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" "Activator, Developmental protein, DNA-binding, Repressor" "Cataract, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 43 "retina: 73.6" "Group enriched" "Detected in some" 10 "Bipolar cells: 152.4;Muller glia cells: 86.0" "Cancer enriched" "Detected in single" 34 "testis cancer: 2.5" "Region enhanced" "Detected in some" "pons: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "midbrain: 1.3;pons and medulla: 1.7" "Region enhanced" "Detected in single" "pons: 1.7" HPA003436 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 56: Bipolar cells - Visual perception" "HPA003436: AB_1078523" "unprognostic (2.87e-1)" "unprognostic (1.22e-1)" "unprognostic (2.79e-1)" "unprognostic (3.29e-1)" "unprognostic (3.21e-4)" "unprognostic (7.77e-2)" "unprognostic (8.39e-4)" "unprognostic (3.13e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 73.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.2 0.5 1.7 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 152.4 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.6 86.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WASHC5 "KIAA0196, SPG8" ENSG00000164961 "WASH complex subunit 5" Q12768 8 125024260-125091819 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 19.8;Exocrine glandular cells: 17.2;Hofbauer cells: 21.8;Proximal tubular cells: 17.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034216, CAB034219, HPA064649, HPA070916" Supported Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB034216: AB_2234159, CAB034219: AB_2130519, HPA064649: AB_2685312, HPA070916: AB_2686322" "unprognostic (1.98e-3)" "unprognostic (3.75e-2)" "unprognostic (8.40e-2)" "unprognostic (3.89e-3)" "unprognostic (2.98e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (6.74e-5)" "unprognostic (2.54e-2)" "unprognostic (3.54e-1)" "unprognostic (5.69e-2)" "unprognostic (9.10e-3)" "unprognostic (1.53e-1)" "unprognostic (9.39e-3)" "unprognostic (5.95e-2)" "unprognostic (2.17e-1)" "unprognostic (1.62e-1)" "unprognostic (2.33e-2)" 18.1 18.6 10.5 18.5 16.9 21.3 19.6 14.9 13.2 17.2 16.5 18.5 18.1 16.2 15.7 16.6 13.3 17.8 16.1 11.1 12.5 22.9 18.5 17.1 19.6 14.7 13.7 15.6 13.0 24.8 9.5 21.2 14.6 17.4 20.1 11.4 14.3 16.1 15.9 13.6 14.7 20.2 14.0 19.3 16.1 9.5 13.8 21.8 23.3 18.5 21.0 21.1 10.3 24.7 40.0 45.4 24.9 30.6 55.3 58.8 16.3 42.0 63.6 43.0 45.8 17.0 42.1 36.1 29.1 54.1 25.3 30.6 40.2 37.7 56.8 47.5 23.1 48.1 26.5 22.8 53.8 14.8 46.6 58.7 25.1 35.5 31.2 33.2 49.9 30.9 28.3 35.6 53.0 87.6 44.3 11.8 23.7 66.7 46.7 29.8 22.4 36.7 33.2 48.5 13.1 26.3 48.8 109.2 39.5 25.8 47.3 25.5 44.7 23.6 51.9 39.4 37.7 31.7 31.2 31.7 62.4 27.5 33.4 10.4 17.0 12.5 13.5 20.9 14.3 9.5 12.8 13.9 19.7 10.6 10.1 14.3 5.8 17.2 29.3 7.2 16.9 13.0 10.5 16.9 14.9 13.2 11.1 12.5 14.7 13.7 14.6 14.0 13.8 24.7 10.9 3.2 19.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 14.4 9.3 0.0 0.0 5.0 11.0 0.0 13.4 6.9 0.0 5.9 12.2 0.0 9.9 13.5 4.9 0.0 0.0 0.0 17.2 11.0 5.4 0.0 14.8 8.8 11.1 0.0 0.0 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 5.7 0.0 0.0 0.0 0.0 16.2 0.0 0.0 1.9 0.0 0.0 17.2 4.4 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 12.3 3.8 9.6 0.0 0.0 WDFY3 "ALFY, KIAA0993, ZFYVE25" ENSG00000163625 "WD repeat and FYVE domain containing 3" Q8IZQ1 4 84669597-84966690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Developmental protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 44.9" "Group enriched" "Detected in many" 5 "Astrocytes: 241.0;Excitatory neurons: 231.0;Inhibitory neurons: 248.7;Microglial cells: 209.9;Oligodendrocyte precursor cells: 262.9;Oligodendrocytes: 440.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "TIME: 57.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042734, HPA048572" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Nucleoli, Plasma membrane" "HPA042734: AB_2678135, HPA048572: AB_2680447" "unprognostic (7.14e-2)" "unprognostic (6.02e-2)" "unprognostic (7.68e-2)" "unprognostic (1.60e-1)" "unprognostic (1.84e-2)" "unprognostic (2.48e-1)" "unprognostic (2.86e-2)" "unprognostic (3.36e-1)" "unprognostic (1.01e-1)" "unprognostic (4.33e-2)" "unprognostic (3.36e-1)" "unprognostic (7.12e-2)" "prognostic favorable (3.64e-5)" "prognostic unfavorable (9.35e-4)" "unprognostic (2.79e-1)" "unprognostic (4.41e-2)" "unprognostic (4.95e-2)" 8.6 8.6 14.8 7.6 31.7 14.4 8.7 26.8 22.9 8.5 4.7 5.7 3.6 8.2 6.4 7.4 8.2 8.8 5.7 16.3 15.6 20.1 5.6 7.4 2.6 30.6 30.4 13.6 9.0 16.3 6.5 11.8 28.7 8.6 5.6 26.2 7.2 7.4 5.9 10.8 4.7 8.5 21.7 7.8 5.6 8.1 25.6 3.4 11.7 13.2 2.3 8.7 5.7 44.9 11.9 7.8 14.3 7.9 24.8 19.3 9.0 11.2 11.8 11.5 10.3 9.1 9.6 0.0 11.3 18.8 12.3 5.9 15.4 12.3 14.6 7.9 4.9 7.5 9.0 5.5 9.4 5.9 13.7 14.2 10.9 15.0 15.1 13.9 37.1 6.0 7.5 35.3 21.4 8.5 5.7 1.4 7.4 11.4 4.0 8.4 11.4 1.8 19.6 15.6 16.8 7.8 13.8 15.1 7.5 13.5 7.9 14.4 57.0 15.1 14.9 8.5 14.1 0.1 0.0 0.0 10.2 5.0 16.9 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.1 14.8 31.7 26.8 22.9 16.3 15.6 30.6 30.4 28.7 21.7 25.6 44.9 28.5 19.2 12.9 241.0 1.0 14.7 9.1 12.4 11.4 46.6 13.8 11.3 18.2 20.0 14.7 16.5 35.5 11.8 0.5 6.5 1.9 8.6 6.7 27.1 27.8 20.1 9.1 1.3 231.0 7.3 6.9 19.5 15.3 43.4 0.0 31.0 17.9 8.1 20.5 28.6 248.7 7.8 20.3 43.1 14.1 10.1 18.3 29.9 7.2 209.9 19.7 28.7 0.0 262.9 440.4 10.7 6.5 24.5 0.2 13.6 4.8 18.4 15.5 41.9 26.3 30.0 22.8 11.4 7.3 14.1 16.1 14.5 1.8 15.0 6.7 13.6 WDPCP "BBS15, C2orf86, CPLANE5, fritz, hFrtz" ENSG00000143951 "WD repeat containing planar cell polarity effector" O95876 2 63119559-63827843 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 18.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 169.9;Alveolar cells type 2: 128.0;Astrocytes: 124.7;Excitatory neurons: 261.4;Inhibitory neurons: 240.9;Oligodendrocyte precursor cells: 136.2;Oligodendrocytes: 296.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044144 Uncertain Approved "Cell Junctions" Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 6: Brain - Smell perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "HPA044144: AB_10969458" "unprognostic (3.36e-1)" "unprognostic (3.22e-2)" "unprognostic (1.95e-1)" "unprognostic (7.07e-2)" "unprognostic (2.95e-1)" "unprognostic (6.88e-2)" "unprognostic (1.71e-1)" "unprognostic (1.59e-3)" "unprognostic (7.22e-2)" "unprognostic (6.48e-2)" "unprognostic (1.93e-1)" "unprognostic (4.87e-2)" "unprognostic (2.34e-3)" "unprognostic (6.02e-2)" "unprognostic (1.97e-1)" "unprognostic (2.25e-3)" "unprognostic (2.00e-1)" 4.7 3.5 11.3 2.5 11.7 8.2 3.2 17.7 15.7 2.5 6.5 1.6 1.8 3.9 4.0 2.0 4.2 2.8 4.9 10.4 6.9 3.6 2.4 2.5 3.3 6.4 5.4 4.6 1.5 2.9 1.9 2.6 8.4 2.6 1.8 12.2 2.2 2.1 5.3 3.4 1.7 3.0 3.2 3.3 3.3 5.1 6.3 3.6 3.5 2.9 2.7 1.8 1.1 18.6 5.2 4.6 3.3 4.0 3.7 4.6 3.0 4.3 2.2 2.8 2.3 3.3 2.6 5.8 3.5 2.9 3.3 3.4 2.3 2.8 3.3 5.7 3.8 6.1 3.5 2.8 2.5 5.0 4.1 2.3 1.9 2.9 1.9 3.7 2.9 6.7 2.3 5.7 2.9 5.3 5.8 5.1 3.9 2.7 1.7 6.2 4.3 5.0 1.9 2.5 5.2 5.2 3.7 4.4 5.3 4.7 3.8 3.9 4.7 4.6 7.2 4.0 3.6 5.3 3.6 10.3 5.2 5.3 5.3 6.6 2.8 1.5 1.9 1.5 3.7 1.8 1.7 2.6 2.3 3.1 2.3 3.6 1.9 3.8 1.3 2.7 1.5 1.1 11.3 11.7 17.7 15.7 10.4 6.9 6.4 5.4 8.4 3.2 6.3 18.6 6.0 169.9 128.0 124.7 8.0 4.1 3.2 4.3 2.8 16.1 4.4 3.2 10.1 7.2 59.6 1.8 22.9 2.5 5.5 0.8 1.9 2.6 46.7 17.9 6.2 14.4 0.0 7.8 261.4 2.2 2.6 13.5 6.6 3.7 65.0 7.4 5.0 1.8 4.0 11.8 240.9 1.3 4.1 3.0 4.4 17.5 4.4 8.4 5.4 103.0 3.8 7.5 6.2 136.2 296.3 1.8 1.6 3.8 5.1 1.5 0.5 4.5 98.8 27.4 0.0 8.6 5.7 16.1 9.5 2.3 3.4 1.9 9.4 4.0 1.1 1.7 WDR19 "DYF-2, FAP66, FLJ23127, IFT144, KIAA1638, NPHP13, ORF26, Oseg6, Pwdmp" ENSG00000157796 "WD repeat domain 19" Q8NEZ3 4 39182504-39285810 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 61.8;Inhibitory neurons: 82.5;Respiratory ciliated cells: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 45.3;ASC TERT1: 47.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039616, HPA058847" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Centrosome, Cytosol" "HPA039616: AB_10796331, HPA058847: AB_2683834" "unprognostic (1.80e-1)" "unprognostic (9.32e-2)" "unprognostic (6.40e-2)" "unprognostic (5.69e-2)" "unprognostic (1.37e-1)" "unprognostic (1.26e-3)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.06e-1)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "prognostic favorable (2.70e-4)" "prognostic unfavorable (8.58e-4)" "unprognostic (3.52e-2)" "unprognostic (2.40e-2)" "unprognostic (5.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.56e-2)" 7.5 8.0 3.1 5.3 2.5 3.7 9.2 5.3 3.8 10.5 10.8 6.8 1.9 16.0 13.3 3.9 20.3 8.4 4.2 2.3 2.5 8.8 6.3 8.8 4.7 5.3 3.6 17.9 5.4 8.1 9.1 6.2 2.9 7.7 4.2 13.0 5.7 8.4 2.3 5.5 4.7 9.1 3.5 4.6 6.2 14.0 2.7 6.9 16.7 2.4 4.9 6.2 6.8 3.6 6.1 5.2 10.3 12.1 45.3 47.0 4.7 7.5 17.2 8.1 10.6 2.8 6.5 10.4 4.1 7.8 17.2 4.0 10.9 5.4 8.6 0.5 8.5 2.2 10.3 6.1 16.1 9.6 2.6 30.5 11.1 11.9 7.2 24.6 10.7 11.0 8.7 9.1 9.9 2.1 7.7 8.1 3.5 3.7 5.6 8.2 10.4 4.2 7.0 2.9 11.5 10.4 10.2 2.4 6.1 13.1 5.5 3.6 7.9 7.9 5.3 17.5 7.8 7.2 7.6 7.6 11.9 3.3 3.7 0.1 0.3 0.2 0.3 0.5 0.3 0.8 0.5 0.6 0.3 1.2 0.5 0.6 0.3 0.8 0.5 0.1 0.3 0.2 3.1 2.5 5.3 3.8 2.3 2.5 5.3 3.6 2.9 3.5 2.7 3.6 5.5 12.8 9.3 26.1 5.4 4.8 4.9 4.6 2.2 10.1 7.3 7.4 4.5 2.8 9.4 18.4 10.4 1.2 1.8 0.7 0.0 5.5 5.1 32.3 14.6 6.7 2.4 4.0 61.8 3.6 3.2 10.8 2.0 12.0 2.5 13.4 4.2 10.0 3.2 25.2 82.5 2.0 12.2 3.2 3.6 3.4 16.4 3.0 1.8 19.7 1.8 6.7 1.0 18.1 19.7 2.9 0.2 18.8 3.9 3.0 0.3 4.0 46.6 21.7 0.0 10.9 7.9 33.8 10.2 3.9 4.7 1.4 2.9 13.1 1.1 1.9 WDR26 "FLJ21016, GID7" ENSG00000162923 "WD repeat domain 26" Q9H7D7 1 224385146-224437033 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 243.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028538, HPA028539, HPA061094" Enhanced Enhanced Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" Mitochondria "HPA028538: , HPA028539: AB_10669752, HPA061094: AB_2684427" "unprognostic (4.09e-3)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (1.31e-2)" "unprognostic (6.67e-2)" "unprognostic (2.27e-1)" "unprognostic (1.24e-1)" "unprognostic (1.64e-1)" "unprognostic (8.42e-2)" "unprognostic (6.32e-2)" "unprognostic (5.59e-2)" "unprognostic (4.18e-1)" "prognostic unfavorable (3.31e-6)" "unprognostic (8.40e-3)" "unprognostic (4.00e-1)" "unprognostic (2.17e-1)" "unprognostic (2.28e-1)" 33.7 28.3 21.9 32.1 21.3 88.9 26.7 20.0 22.0 28.9 27.5 28.9 21.2 26.5 20.8 52.1 22.7 27.1 28.0 23.4 22.8 23.7 35.4 35.1 33.8 21.5 22.0 24.3 24.4 26.4 20.6 35.6 20.2 26.1 25.4 31.5 28.7 25.0 57.1 40.9 26.5 28.6 18.8 38.2 26.7 37.4 22.1 36.0 26.0 45.0 33.2 32.6 31.5 21.9 49.7 28.0 54.6 29.7 76.8 74.6 47.6 58.4 86.4 51.7 48.0 39.0 46.8 51.9 74.4 86.3 21.7 40.6 40.2 47.2 76.1 55.3 53.6 36.2 31.5 31.0 74.7 40.3 68.6 70.8 58.4 55.0 52.1 72.6 80.8 31.7 52.7 51.4 62.4 24.8 42.4 34.7 65.7 41.5 32.0 42.6 66.1 44.2 55.1 48.3 29.5 56.0 64.8 94.9 74.9 55.5 117.5 67.0 88.7 47.7 28.7 41.5 71.3 66.8 33.6 35.2 53.3 26.1 66.8 2.1 1.0 2.1 1.4 1.4 0.8 0.8 0.8 1.0 0.9 0.6 0.7 1.0 4.8 1.5 2.4 1.0 1.1 0.8 21.9 21.3 20.0 22.0 23.4 22.8 21.5 22.0 20.2 18.8 22.1 21.9 32.6 105.8 54.2 55.2 34.4 111.4 29.6 30.9 43.3 24.6 54.1 30.5 49.2 40.0 48.2 35.0 31.3 30.4 54.3 34.8 5.9 22.2 243.3 60.6 35.2 44.2 35.4 53.7 63.4 23.8 15.7 37.9 26.5 71.0 48.1 34.1 41.4 44.2 53.4 38.7 61.3 44.4 40.7 133.4 96.4 102.1 37.0 74.5 46.2 67.5 45.7 16.3 32.0 63.3 70.0 34.2 26.2 28.2 33.0 49.0 19.2 22.8 55.4 24.2 19.7 35.2 41.4 37.1 25.8 63.9 122.3 68.3 45.1 37.9 25.0 63.7 WDR35 "FAP118, IFT121, IFTA1, KIAA1336, MGC33196" ENSG00000118965 "WD repeat domain 35" Q9P2L0 2 19910263-19990105 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 36.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044147 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "HPA044147: AB_10970242" "unprognostic (2.51e-1)" "unprognostic (4.93e-2)" "unprognostic (9.13e-2)" "unprognostic (4.01e-2)" "unprognostic (3.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.94e-3)" "unprognostic (3.08e-2)" "unprognostic (3.23e-1)" "unprognostic (2.91e-1)" "unprognostic (3.01e-2)" "unprognostic (3.68e-2)" "unprognostic (6.98e-2)" "unprognostic (2.17e-2)" "unprognostic (5.03e-2)" "unprognostic (1.02e-1)" "unprognostic (2.71e-1)" 3.6 5.1 4.3 2.7 4.4 2.0 7.8 4.1 4.7 6.6 10.0 4.9 1.7 9.3 7.2 2.9 11.3 3.5 3.3 4.1 5.5 7.9 2.0 4.5 2.7 5.5 5.5 9.6 3.8 14.4 9.0 2.7 5.1 5.5 3.0 12.6 3.0 6.3 2.5 3.4 3.0 6.2 4.9 2.0 3.7 10.6 6.0 4.8 8.8 2.6 2.6 4.4 3.7 5.7 8.3 10.4 9.9 9.5 7.6 7.4 0.5 4.2 7.4 6.0 4.3 3.2 3.6 0.0 1.8 4.7 5.0 2.6 10.6 10.3 9.9 1.6 8.2 8.1 6.6 10.0 6.6 15.8 3.1 9.0 7.2 10.7 15.2 10.8 7.4 3.3 13.1 2.3 6.1 3.0 2.3 11.4 11.9 1.5 10.0 0.0 7.1 3.5 12.8 4.7 18.6 21.9 6.9 4.6 12.3 4.7 4.9 3.4 7.7 6.8 3.3 9.4 12.4 4.7 8.3 0.0 12.7 1.1 6.8 2.9 0.1 0.3 0.5 0.0 0.1 0.4 0.3 0.3 0.2 0.6 0.3 0.4 0.2 0.4 0.0 0.1 0.4 0.2 4.3 4.4 4.1 4.7 4.1 5.5 5.5 5.5 5.1 4.9 6.0 5.7 2.9 3.2 9.0 36.6 5.7 3.3 3.5 5.0 2.2 6.5 5.8 7.2 10.8 11.5 7.2 11.0 2.1 0.2 2.9 0.3 0.0 3.3 1.9 16.1 13.1 3.1 6.0 7.8 30.0 4.0 1.0 9.7 5.1 4.0 9.5 9.4 3.6 2.4 1.3 6.7 21.9 1.5 4.1 0.9 2.8 3.5 10.2 2.0 3.6 18.7 1.1 10.0 2.1 25.1 27.6 6.3 0.7 10.9 2.4 2.0 0.7 5.6 28.6 15.2 6.6 14.6 7.4 28.8 9.0 2.2 2.6 0.3 5.4 9.0 1.5 1.1 WDR4 "TRM82, TRMT82" ENSG00000160193 "WD repeat domain 4" P57081 21 42843094-42879568 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, tRNA processing" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 25.8;Prostatic glandular cells: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017381 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA017381: AB_1858807" "unprognostic (3.47e-2)" "unprognostic (2.15e-2)" "unprognostic (4.32e-2)" "unprognostic (2.13e-2)" "unprognostic (2.95e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (5.48e-7)" "unprognostic (2.85e-3)" "unprognostic (5.37e-2)" "unprognostic (2.27e-2)" "unprognostic (4.25e-1)" "unprognostic (4.78e-2)" "unprognostic (2.65e-2)" "unprognostic (1.74e-3)" "unprognostic (1.44e-1)" "unprognostic (1.74e-1)" "unprognostic (4.46e-2)" 5.1 4.7 4.0 7.2 3.9 6.7 3.9 3.8 4.8 4.3 3.4 3.8 5.0 5.1 1.9 9.1 4.1 1.8 3.5 3.8 3.4 4.8 6.0 3.8 9.3 4.3 3.9 4.3 5.6 2.9 2.3 4.1 4.4 3.4 3.1 1.6 3.6 2.6 6.7 5.0 4.0 3.3 3.9 5.4 3.6 4.7 4.0 5.3 4.1 3.2 7.3 5.7 5.0 4.5 35.7 48.5 12.9 18.5 6.9 8.2 30.7 20.2 7.3 16.9 10.7 48.9 18.1 58.8 11.5 14.5 24.5 19.3 44.7 25.5 11.8 19.2 42.0 59.7 52.0 41.9 13.3 36.8 14.5 4.7 11.2 22.9 16.4 6.3 22.1 20.9 72.6 22.0 14.8 29.4 38.5 20.9 32.3 26.4 47.0 41.6 7.8 58.4 12.8 21.2 30.4 19.5 21.2 31.1 10.2 4.1 20.4 28.2 16.4 25.9 17.3 12.1 41.0 28.9 21.6 48.1 12.5 57.2 31.1 0.0 3.9 0.2 2.4 6.8 3.6 5.4 3.4 3.1 7.1 4.9 3.4 3.5 0.0 3.6 4.2 3.5 4.4 3.5 4.0 3.9 3.8 4.8 3.8 3.4 4.3 3.9 4.4 3.9 4.0 4.5 3.6 0.0 4.8 5.5 10.3 8.5 12.7 7.3 4.0 4.1 5.3 4.6 2.5 0.0 3.2 0.0 2.1 16.3 5.5 5.9 0.0 7.4 4.8 2.8 5.8 5.2 5.4 8.4 4.8 6.7 25.8 4.7 6.1 3.4 10.2 5.4 3.6 7.0 12.5 3.3 4.5 6.0 4.1 3.5 4.0 3.8 2.8 4.7 7.2 2.8 1.9 3.8 2.1 1.5 5.1 6.9 1.0 3.0 15.3 24.6 3.5 6.8 2.1 4.6 6.6 2.7 6.1 10.4 8.4 7.5 10.9 11.5 3.6 8.2 7.7 10.7 WDR45B "WDR45L, WIPI3" ENSG00000141580 "WD repeat domain 45B" Q5MNZ6 17 82614562-82648553 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 462.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017886 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" Cytosol "HPA017886: AB_1858810" "unprognostic (1.91e-1)" "unprognostic (7.77e-2)" "unprognostic (5.13e-2)" "unprognostic (3.78e-2)" "unprognostic (1.42e-1)" "unprognostic (3.88e-2)" "prognostic unfavorable (2.98e-5)" "unprognostic (1.23e-1)" "unprognostic (6.38e-2)" "unprognostic (1.22e-2)" "unprognostic (4.41e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-2)" "unprognostic (9.93e-3)" "unprognostic (8.89e-2)" "unprognostic (4.27e-2)" "unprognostic (1.02e-1)" 39.4 44.5 50.7 22.4 56.1 58.7 37.6 52.4 50.4 35.6 41.4 33.6 30.8 37.9 30.1 59.3 43.6 36.8 37.0 48.9 50.9 37.3 32.4 32.9 23.3 53.0 51.7 50.1 46.1 46.2 36.8 25.5 50.7 37.5 25.9 30.9 46.6 28.5 24.4 46.9 34.4 27.5 54.3 28.6 39.9 50.0 54.6 23.8 32.1 26.8 25.8 39.8 40.1 60.3 100.5 65.1 56.0 54.6 53.8 44.4 63.0 71.1 77.7 106.4 93.5 78.7 53.8 27.9 44.8 64.2 76.9 52.4 52.8 58.5 101.4 18.6 93.7 55.4 40.5 67.8 64.1 42.8 42.8 50.9 61.7 62.1 57.3 52.1 88.2 38.0 41.6 27.8 63.0 66.8 31.3 37.6 72.3 86.8 78.2 36.6 92.0 28.1 65.0 99.3 68.3 100.9 66.9 74.7 90.7 67.6 86.9 39.2 63.6 120.0 94.4 81.5 135.8 66.5 29.7 40.5 76.8 42.9 87.0 34.2 27.5 33.9 16.4 27.6 16.6 13.4 12.5 13.7 22.2 12.8 10.9 10.5 21.9 13.9 22.8 10.9 11.3 19.3 50.7 56.1 52.4 50.4 48.9 50.9 53.0 51.7 50.7 54.3 54.6 60.3 62.1 32.1 47.3 17.0 51.5 59.9 48.6 71.5 48.3 39.7 76.3 54.0 21.2 60.1 84.4 42.3 12.5 54.4 49.6 85.6 88.0 128.8 152.7 145.2 72.5 56.1 47.4 14.5 16.9 137.7 77.3 44.9 43.3 177.1 73.5 32.7 47.2 71.5 45.8 45.4 20.0 68.0 67.1 62.0 42.5 462.7 57.2 72.8 56.9 15.9 57.8 66.2 44.3 13.0 24.6 157.6 55.4 48.2 24.8 72.8 58.3 71.5 91.1 34.9 32.9 44.6 53.2 94.5 171.6 53.8 72.5 108.1 46.7 37.0 68.3 101.0 WDR62 "C19orf14, DKFZP434J046, FLJ33298, MCPH2" ENSG00000075702 "WD repeat domain 62" O43379 19 36054649-36105108 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 110.3;testis: 63.7;tongue: 63.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 43.4;Cone photoreceptor cells: 85.5;Early spermatids: 42.5;Late spermatids: 46.2;Rod photoreceptor cells: 41.7;Spermatocytes: 67.6" "Cancer enhanced" "Detected in many" "testis cancer: 10.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.7" "Lineage enriched" "Detected in single" 4 "monocytes: 2.7" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043255, HPA043639" Enhanced Enhanced "Centriolar satellite,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Centriolar satellite" "HPA043255: AB_2678393, HPA043639: AB_2678593" "unprognostic (1.77e-1)" "unprognostic (2.79e-3)" "unprognostic (3.16e-2)" "unprognostic (4.88e-2)" "unprognostic (1.77e-1)" "unprognostic (4.22e-3)" "unprognostic (1.78e-4)" "unprognostic (2.00e-1)" "unprognostic (4.00e-2)" "unprognostic (5.82e-3)" "unprognostic (4.72e-2)" "unprognostic (4.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.73e-3)" "unprognostic (2.72e-1)" "unprognostic (1.50e-1)" "unprognostic (2.67e-1)" 0.4 0.4 0.3 2.1 0.5 5.4 0.4 0.9 0.7 0.9 0.2 0.9 1.1 0.6 0.2 3.7 0.7 0.2 22.1 0.4 0.2 0.4 0.7 0.7 2.9 0.5 0.5 0.3 0.2 0.1 0.4 0.5 0.5 0.7 0.5 6.7 1.3 0.2 110.3 2.7 1.2 0.7 0.2 2.0 0.9 63.7 0.4 5.0 0.4 63.1 1.8 0.3 1.4 0.8 19.9 37.8 12.3 12.6 1.1 0.3 7.8 18.0 7.6 24.1 20.8 20.0 6.7 24.7 10.9 9.3 11.3 6.1 18.6 6.8 13.5 16.1 8.8 16.9 20.5 13.5 0.8 16.8 19.6 0.3 0.7 17.7 5.2 1.7 6.0 17.3 21.7 26.8 11.3 20.6 33.1 9.0 7.3 16.0 7.4 23.3 12.5 11.7 3.3 7.5 15.3 8.6 12.1 16.7 2.8 7.6 9.6 14.3 4.1 20.8 19.9 16.7 29.6 14.0 22.1 32.0 9.1 13.0 24.6 0.5 0.1 0.1 0.1 0.7 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.6 0.2 2.7 0.1 0.5 0.1 0.3 0.5 0.9 0.7 0.4 0.2 0.5 0.5 0.5 0.2 0.4 0.8 1.8 0.0 5.5 0.3 1.0 2.2 1.3 0.5 0.6 1.6 0.9 0.6 43.4 0.0 0.8 0.0 85.5 1.9 1.2 2.5 1.9 0.4 42.5 0.8 0.8 2.0 0.0 11.0 1.4 0.9 1.9 1.8 5.6 0.8 0.0 4.3 1.1 0.8 2.2 3.3 1.0 2.2 2.0 1.3 1.6 46.2 1.2 1.9 1.8 1.0 0.8 2.1 0.0 1.0 1.0 0.5 0.2 0.4 7.1 0.8 0.3 0.3 0.2 41.7 6.6 2.8 1.9 67.6 15.4 2.0 3.7 0.3 2.2 1.2 3.0 0.7 WDR73 "FLJ14888, HSPC264" ENSG00000177082 "WD repeat domain 73" Q6P4I2 15 84639285-84654343 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 98.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039357 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 51: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" "HPA039357: AB_10673242" "unprognostic (8.49e-2)" "unprognostic (2.16e-1)" "unprognostic (4.77e-2)" "unprognostic (6.86e-2)" "unprognostic (1.74e-1)" "unprognostic (1.48e-1)" "unprognostic (1.18e-2)" "unprognostic (6.59e-2)" "unprognostic (1.02e-1)" "unprognostic (2.32e-2)" "unprognostic (1.26e-2)" "unprognostic (7.19e-4)" "unprognostic (9.21e-4)" "unprognostic (4.12e-1)" "unprognostic (3.16e-2)" "unprognostic (8.58e-2)" "unprognostic (4.02e-2)" 2.2 3.6 1.8 2.2 2.1 2.8 3.3 3.0 2.3 3.2 3.1 3.2 2.3 3.4 4.2 2.7 3.3 1.5 2.2 2.3 2.1 3.2 2.3 2.4 2.3 2.0 2.2 3.3 3.1 3.7 3.2 1.6 2.3 3.5 2.7 3.4 2.9 2.4 2.2 3.0 3.1 2.9 1.8 3.3 2.9 1.8 2.1 3.0 3.9 1.8 2.8 2.9 2.8 2.8 2.8 4.6 5.5 2.7 2.7 3.1 2.8 1.4 2.7 2.4 1.8 4.3 4.7 3.2 1.5 4.7 2.5 6.6 6.4 4.3 2.6 1.7 3.4 2.3 5.5 2.5 3.7 3.4 3.2 5.6 4.0 3.9 5.5 4.5 2.2 3.9 3.9 1.8 1.4 4.7 4.0 5.1 4.7 2.9 1.9 4.2 4.1 2.4 3.7 7.0 3.5 5.8 3.6 5.1 5.8 3.0 8.4 6.5 2.4 2.9 3.3 3.1 4.2 3.4 6.0 2.6 5.1 5.7 4.2 0.4 0.3 0.4 0.4 0.4 0.4 0.3 0.2 0.4 0.1 0.6 0.3 0.3 0.8 0.4 0.2 0.3 0.1 0.4 1.8 2.1 3.0 2.3 2.3 2.1 2.0 2.2 2.3 1.8 2.1 2.8 17.0 25.6 32.8 21.9 17.5 5.4 18.9 18.6 12.5 48.4 16.9 20.1 1.1 27.1 25.9 29.5 73.0 33.6 14.4 13.9 23.5 27.6 4.8 32.2 26.3 14.9 18.0 14.3 13.6 14.0 16.1 18.2 16.3 21.8 17.1 38.0 18.9 9.5 13.2 40.4 15.2 13.8 22.4 10.7 5.1 2.3 22.7 9.8 5.4 15.0 17.4 36.8 21.6 13.6 12.2 17.3 11.5 16.1 8.4 17.7 10.1 20.7 70.1 98.5 6.6 27.2 17.7 44.9 18.0 8.7 5.3 25.7 17.1 44.5 15.0 13.9 WDR81 "CAMRQ2, FLJ33817, PPP1R166, SORF-2" ENSG00000167716 "WD repeat domain 81" Q562E7 17 1716523-1738599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023044, HPA063703" Uncertain Approved Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Vesicles, Cytosol" "HPA023044: AB_1858822, HPA063703: " "unprognostic (1.00e-1)" "unprognostic (4.67e-2)" "unprognostic (6.63e-2)" "unprognostic (4.90e-3)" "unprognostic (6.10e-2)" "unprognostic (7.75e-3)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (3.06e-2)" "unprognostic (1.60e-2)" "prognostic favorable (3.30e-4)" "unprognostic (3.26e-1)" "unprognostic (8.72e-2)" "unprognostic (2.25e-1)" "unprognostic (8.43e-2)" "unprognostic (7.99e-2)" "unprognostic (3.90e-2)" 17.7 16.2 4.5 4.6 5.4 4.9 16.9 4.6 6.3 18.2 6.6 11.5 4.8 18.9 2.4 9.9 17.4 1.6 10.9 4.3 4.4 11.9 32.8 13.7 5.6 5.9 5.1 21.4 11.0 2.4 13.1 3.9 5.3 16.0 1.7 0.8 11.0 5.9 18.2 18.4 17.8 5.1 4.7 24.3 11.0 7.5 6.1 6.6 10.5 2.1 4.2 15.4 13.7 6.4 0.7 12.3 1.7 9.1 12.4 7.0 9.2 0.9 0.2 0.6 0.0 1.8 4.4 4.9 6.5 5.4 6.2 12.2 6.3 8.4 0.4 9.5 12.8 0.3 8.8 5.9 22.1 4.1 7.6 17.8 8.8 5.9 4.1 1.9 5.0 3.7 1.0 6.3 7.6 6.8 1.3 7.6 3.9 4.2 9.4 6.4 2.9 6.8 3.7 2.0 2.2 5.0 4.3 3.4 15.4 0.1 6.0 6.1 6.8 4.8 5.4 7.9 6.7 0.5 1.3 3.1 7.7 5.9 2.4 0.0 1.4 2.8 1.1 2.3 1.3 1.3 1.2 1.2 1.8 1.0 0.8 1.1 0.3 2.1 2.3 3.3 1.2 1.1 4.5 5.4 4.6 6.3 4.3 4.4 5.9 5.1 5.3 4.7 6.1 6.4 6.3 12.8 10.3 6.5 4.2 2.5 2.9 4.4 8.6 4.5 4.8 5.3 3.6 4.3 3.8 0.0 4.2 2.5 9.9 6.8 1.9 3.1 0.7 2.1 6.2 5.4 1.2 14.3 5.3 4.5 1.9 8.2 6.6 2.9 4.5 6.2 4.6 27.7 23.8 5.0 5.3 4.6 10.2 22.3 4.5 1.2 16.4 15.3 0.0 9.4 7.5 2.5 9.2 5.0 7.6 4.8 4.8 15.1 5.3 2.9 8.7 20.1 6.4 1.8 19.7 5.9 4.5 0.7 2.0 3.4 1.7 2.3 4.7 5.8 4.4 1.7 WNT1 INT1 ENSG00000125084 "Wnt family member 1" P04628 12 48978322-48982620 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Osteogenesis imperfecta, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 4.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.1;Gastric mucus-secreting cells: 1.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basal ganglia: 4.5;cerebral cortex: 2.1" "Group enriched" "Detected in some" 8 "gdT-cell: 3.1;MAIT T-cell: 5.1;memory CD4 T-cell: 2.0;memory CD8 T-cell: 2.9;naive CD8 T-cell: 2.1" "Lineage enriched" "Detected in single" 29 "T-cells: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.1" "Secreted to extracellular matrix" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.02e-2)" "unprognostic (5.80e-3)" "unprognostic (1.23e-1)" "unprognostic (1.64e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-3)" "unprognostic (5.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.63e-1)" "unprognostic (1.20e-1)" "unprognostic (4.08e-2)" "unprognostic (4.97e-2)" "unprognostic (1.32e-2)" "unprognostic (1.67e-2)" "unprognostic (1.70e-1)" "unprognostic (7.35e-3)" "unprognostic (2.76e-2)" 0.0 0.0 0.8 0.5 4.5 1.1 0.0 0.0 2.1 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.2 0.1 0.7 0.2 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.3 0.7 0.3 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 5.1 0.1 2.0 2.9 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.0 0.2 0.5 0.8 4.5 0.0 2.1 0.7 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 WNT10A ENSG00000135925 "Wnt family member 10A" Q9GZT5 2 218880852-218899581 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant, Ectodermal dysplasia, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 7.0;skin 1: 8.9" "Cell type enhanced" "Detected in many" "B-cells: 12.2;Basal keratinocytes: 17.1;Basal respiratory cells: 15.5;Basal squamous epithelial cells: 30.1;Bipolar cells: 16.2;dendritic cells: 16.4;Plasma cells: 30.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.9" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 6.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 6.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 50.8;HaCaT: 140.1;HDLM-2: 58.7;RPTEC TERT1: 29.2;U-266/70: 69.0" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Region enhanced" "Detected in single" "basal ganglia: 2.1" HPA013898 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "HPA013898: AB_1858847" "unprognostic (2.99e-4)" "unprognostic (4.31e-2)" "unprognostic (8.55e-2)" "unprognostic (1.17e-3)" "unprognostic (2.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.62e-1)" "unprognostic (2.56e-2)" "unprognostic (1.04e-1)" "unprognostic (6.34e-2)" "unprognostic (2.23e-3)" "unprognostic (9.52e-2)" "unprognostic (6.64e-9)" "unprognostic (1.22e-1)" "unprognostic (1.72e-1)" "unprognostic (4.89e-3)" "unprognostic (1.82e-1)" 0.7 0.2 0.7 1.0 1.6 0.5 0.5 0.2 1.3 1.5 0.2 1.6 3.7 0.0 0.4 7.0 1.2 0.3 0.1 1.2 0.5 2.4 0.2 0.7 2.5 0.4 0.6 0.2 0.1 0.0 4.3 3.4 0.5 1.7 1.0 1.4 2.5 1.0 0.0 8.9 2.1 0.0 0.3 2.0 2.5 0.4 0.7 1.1 0.2 0.0 1.9 2.7 2.9 0.7 15.8 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 50.8 2.8 10.4 0.0 3.8 140.1 0.0 0.1 0.0 58.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 10.5 29.2 0.4 0.0 0.4 0.3 0.0 0.1 0.8 0.0 0.2 0.0 0.0 0.9 0.0 0.0 69.0 1.1 1.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.7 0.2 0.0 0.0 0.0 0.0 6.2 1.0 0.0 0.7 1.6 0.2 1.3 1.2 0.5 0.4 0.6 0.5 0.3 0.7 0.7 0.2 0.0 0.0 0.3 12.2 17.1 8.2 15.5 30.1 16.2 0.5 1.3 1.4 0.0 1.1 9.2 2.1 1.2 16.4 0.0 0.0 0.3 1.2 0.3 0.1 0.2 0.0 0.4 1.3 0.0 0.4 1.9 0.5 0.2 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.0 2.0 0.0 1.3 0.1 0.6 1.0 7.2 0.0 0.0 0.5 0.0 0.5 0.1 0.1 0.0 0.0 30.4 2.5 0.0 0.3 0.6 1.5 0.0 0.1 0.8 0.9 0.6 5.2 4.7 0.1 9.8 0.0 0.2 3.2 WNT10B "SHFM6, WNT-12" ENSG00000169884 "Wnt family member 10B" O00744 12 48965340-48971735 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.3;Extravillous trophoblasts: 21.7;Fibroblasts: 4.8;Inhibitory neurons: 4.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 7.3;T-47d: 8.2;U-266/84: 7.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA055048, HPA062539" Enhanced Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA055048: AB_2682683, HPA062539: AB_2684793" "unprognostic (1.13e-1)" "unprognostic (2.14e-2)" "unprognostic (5.73e-4)" "unprognostic (2.27e-2)" "unprognostic (3.09e-2)" "unprognostic (3.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.14e-1)" "unprognostic (4.99e-3)" "unprognostic (3.05e-2)" "unprognostic (5.39e-6)" "unprognostic (4.29e-2)" "unprognostic (3.74e-2)" "unprognostic (4.50e-1)" "unprognostic (1.25e-1)" 1.5 0.2 13.1 1.5 14.9 1.2 0.6 4.2 17.9 0.8 3.2 1.4 1.4 0.3 1.5 1.4 1.0 0.5 1.5 15.3 7.3 0.4 0.4 1.1 1.7 8.6 7.6 0.2 0.3 0.1 2.4 0.3 8.2 0.8 0.7 0.1 0.9 0.6 0.7 3.4 4.3 0.1 5.1 4.1 1.1 3.3 10.4 1.9 1.0 0.4 1.5 1.3 1.0 9.8 1.9 1.2 0.0 1.7 0.0 0.0 4.6 1.3 2.4 0.5 0.1 3.6 4.0 0.0 0.3 0.2 1.5 2.2 4.8 0.3 0.2 1.1 6.3 2.1 1.7 0.1 0.0 0.7 2.9 0.0 0.4 0.1 2.1 4.1 0.0 1.5 7.3 0.3 0.7 2.4 0.1 2.5 0.0 1.3 2.5 0.0 0.6 2.2 0.0 0.4 0.1 0.0 0.3 0.1 0.6 2.2 8.2 2.7 0.0 2.5 4.9 0.4 0.6 2.6 7.8 0.0 1.0 5.4 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 13.1 14.9 4.2 17.9 15.3 7.3 8.6 7.6 8.2 5.1 10.4 9.8 0.2 0.0 0.0 0.7 0.2 0.4 0.0 0.0 1.8 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.8 0.2 0.1 0.0 0.0 0.0 7.3 0.0 21.7 4.8 0.0 0.1 0.0 0.0 0.7 0.0 0.3 0.0 4.7 0.2 0.0 0.0 1.2 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.7 3.0 0.9 1.3 1.4 1.6 0.0 0.0 0.1 WNT3 "INT4, MGC131950, MGC138321, MGC138323" ENSG00000108379 "Wnt family member 3" P56703 17 46762506-46833154 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 12.3;skin 1: 27.7" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 44.5;Early spermatids: 27.7;Late spermatids: 63.8;Suprabasal keratinocytes: 17.6" "Cancer enriched" "Detected in many" 6 "testis cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 8.5;U-698: 14.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA049893: " "unprognostic (1.84e-1)" "unprognostic (2.90e-2)" "unprognostic (2.35e-1)" "unprognostic (6.41e-4)" "unprognostic (4.73e-2)" "unprognostic (5.26e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (4.97e-2)" "unprognostic (2.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "unprognostic (1.10e-8)" "unprognostic (1.77e-1)" "unprognostic (2.08e-1)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" 0.8 0.4 1.3 0.4 1.1 0.1 1.0 0.7 1.0 1.0 0.2 0.6 3.4 0.5 0.0 1.3 0.5 0.1 0.9 0.8 1.2 1.7 12.3 0.9 0.2 1.4 1.8 0.5 0.8 2.5 1.7 0.2 1.2 1.3 0.2 0.2 1.2 0.0 0.2 27.7 2.7 0.2 0.7 0.7 0.4 4.4 4.4 0.1 1.3 0.0 0.1 0.4 1.1 0.7 3.9 1.7 8.5 0.0 0.1 0.1 0.7 0.8 0.9 3.0 0.0 2.7 1.7 1.6 2.3 2.1 6.1 1.3 0.4 0.0 3.9 0.0 0.4 0.0 3.0 2.3 0.0 0.1 0.1 0.2 1.8 1.1 2.3 3.5 1.1 2.5 1.5 0.0 1.0 1.7 0.0 1.4 0.0 1.0 2.4 2.9 1.9 0.2 0.6 0.0 0.1 0.7 1.6 0.0 1.2 2.1 0.0 4.0 0.2 3.2 2.1 0.4 1.5 0.6 0.2 14.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 1.1 0.7 1.0 0.8 1.2 1.4 1.8 1.2 0.7 4.4 0.7 0.2 0.0 1.5 3.9 0.5 44.5 0.6 0.6 3.4 1.1 3.0 1.7 1.3 1.5 0.4 0.0 0.0 2.2 0.1 0.7 1.9 0.7 27.7 0.1 0.7 0.5 0.0 0.0 5.4 2.5 0.1 1.1 0.0 0.2 0.0 0.7 0.4 4.0 0.2 8.4 4.3 0.6 0.0 0.0 1.5 63.8 0.3 0.1 1.8 1.0 0.6 0.2 0.0 4.0 1.1 2.9 1.4 0.4 0.0 1.2 3.7 0.5 0.3 0.8 0.0 1.4 1.1 0.9 2.9 0.8 17.6 0.3 0.0 0.3 0.9 0.3 WNT5A hWNT5A ENSG00000114251 "Wnt family member 5A" P41221 3 55465715-55490539 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 27.4;salivary gland: 34.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Basal squamous epithelial cells: 34.7;Club cells: 31.3;Endometrial stromal cells: 101.6;Oligodendrocyte precursor cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 227.2;BJ hTERT+: 315.4;HeLa: 242.1;SiHa: 354.2;U-87 MG: 248.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (2.34e-3)" "unprognostic (1.35e-1)" "prognostic favorable (2.94e-5)" "unprognostic (1.37e-1)" "unprognostic (3.45e-3)" "unprognostic (1.14e-1)" "unprognostic (2.16e-2)" "unprognostic (3.91e-2)" "unprognostic (5.89e-2)" "unprognostic (9.58e-2)" "unprognostic (8.34e-3)" "unprognostic (1.10e-1)" "unprognostic (4.81e-3)" "unprognostic (9.70e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-3)" "unprognostic (3.63e-2)" 2.3 0.8 1.9 3.1 1.9 0.1 4.9 1.7 1.8 5.7 0.6 3.1 3.5 27.4 3.1 16.9 6.7 7.2 1.6 2.5 3.2 2.7 2.6 4.9 2.2 3.9 4.3 9.1 4.3 1.0 1.8 10.8 3.0 4.6 3.2 1.2 34.4 8.3 2.0 2.4 3.8 5.9 3.8 4.0 3.5 1.8 3.1 2.4 2.8 1.7 5.1 18.7 12.1 5.4 0.0 0.4 20.8 0.2 15.8 37.7 0.0 227.2 315.4 46.3 80.4 1.3 0.0 6.6 0.6 132.2 19.5 0.2 10.0 0.2 48.2 0.0 6.2 6.4 242.1 0.1 35.1 0.0 0.4 25.0 5.9 139.2 7.6 22.5 0.1 0.2 0.0 109.5 113.3 0.0 0.1 0.1 11.1 0.5 13.6 0.0 14.1 1.0 6.2 7.6 0.0 1.0 354.2 43.1 0.0 18.0 0.1 0.0 0.0 76.1 13.2 70.0 18.2 25.8 0.0 2.4 248.5 0.3 35.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.9 1.7 1.8 2.5 3.2 3.9 4.3 3.0 3.8 3.1 5.4 1.1 51.3 23.2 4.2 0.0 1.5 1.6 1.4 34.7 13.2 12.1 4.4 4.3 0.0 31.3 12.9 0.0 3.0 0.0 0.2 0.0 0.2 15.8 13.3 101.6 4.3 0.0 0.0 3.0 0.2 0.6 19.9 0.0 13.9 2.5 8.5 1.1 2.6 1.3 0.0 9.0 0.3 10.2 2.4 1.3 4.2 19.6 2.6 0.0 5.6 4.2 1.6 0.0 31.2 0.1 0.4 2.5 30.1 0.1 0.9 2.3 1.0 1.9 1.4 0.0 1.6 7.7 0.1 1.1 17.5 1.6 1.5 1.5 6.5 1.6 9.6 WNT7A Wnt-7a ENSG00000154764 "Wnt family member 7A" O00755 3 13816258-13880071 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;gallbladder: 2.3;placenta: 2.7" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 68.7;Extravillous trophoblasts: 147.5;Pancreatic endocrine cells: 98.8;Syncytiotrophoblasts: 185.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.2;ovarian cancer: 11.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory CD4 T-cell: 1.7;naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 18 "T-cells: 1.7" "Cell line enhanced" "Detected in some" "BEWO: 59.8;EFO-21: 56.0;PC-3: 19.9;RPTEC TERT1: 100.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015719, CAB025894" Approved "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB025894: , HPA015719: AB_1858856" "unprognostic (1.26e-2)" "unprognostic (4.60e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.96e-5)" "unprognostic (3.02e-1)" "unprognostic (1.14e-3)" "unprognostic (2.49e-1)" "unprognostic (3.32e-4)" "unprognostic (2.20e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (7.89e-2)" "unprognostic (3.78e-2)" "unprognostic (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (3.74e-1)" "unprognostic (8.88e-3)" 0.0 0.0 3.6 0.1 3.1 0.1 0.0 1.0 3.7 0.2 0.3 0.0 0.0 1.1 0.2 0.4 0.1 2.3 0.0 2.4 2.1 0.2 0.0 2.0 0.2 5.1 1.9 0.0 0.1 0.0 0.0 2.7 2.5 0.1 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.0 3.4 1.3 0.0 1.3 2.5 0.0 0.0 0.0 0.1 0.3 0.1 2.8 8.6 0.0 0.8 0.0 0.0 0.0 59.8 0.0 0.0 0.0 0.0 0.0 7.6 0.0 56.0 0.0 0.1 11.2 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 1.7 100.3 0.9 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 3.6 3.1 1.0 3.7 2.4 2.1 5.1 1.9 2.5 3.4 2.5 2.8 0.0 12.8 0.0 8.5 0.0 5.9 2.8 2.6 0.0 0.0 0.0 0.0 0.7 8.6 1.4 0.0 0.0 68.7 0.0 0.0 0.0 13.8 17.3 14.5 0.4 0.6 0.0 0.0 4.0 9.1 147.5 0.4 0.0 17.9 0.0 0.0 0.0 0.0 7.4 0.0 2.4 0.0 0.0 0.0 0.0 5.6 0.0 0.1 0.0 1.0 0.0 0.0 0.0 4.5 0.3 98.8 0.0 0.0 0.0 3.3 0.0 0.1 0.2 0.0 0.0 0.0 0.2 6.0 2.3 0.0 1.3 185.7 1.5 0.0 0.0 6.0 WRN "RECQ3, RECQL2" ENSG00000165392 "WRN RecQ like helicase" Q14191 8 31033788-31176138 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 74.7;Early spermatids: 116.3;Oligodendrocytes: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028661 Approved Supported "Nuclear speckles" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "HPA028661: AB_10602255" "unprognostic (8.73e-2)" "unprognostic (9.33e-2)" "unprognostic (1.51e-3)" "unprognostic (3.85e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-2)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.27e-2)" "unprognostic (6.63e-2)" "unprognostic (1.53e-2)" "unprognostic (6.51e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-2)" "unprognostic (2.66e-1)" 3.0 3.6 1.7 3.2 1.7 8.2 4.8 4.1 2.4 3.0 2.6 3.5 1.5 6.4 3.2 2.7 2.9 2.4 1.7 1.6 1.7 2.1 2.5 2.4 2.5 1.8 2.1 5.2 2.6 2.0 2.1 3.6 1.8 3.5 2.9 4.4 3.5 2.6 2.1 4.1 2.5 4.2 1.2 3.1 2.3 3.0 1.9 3.2 3.2 2.2 3.0 2.6 2.3 3.1 4.4 5.9 10.8 5.3 6.7 9.8 5.0 4.7 4.9 6.4 6.6 2.7 1.5 10.0 4.6 4.3 4.4 2.4 6.4 3.8 9.7 3.3 4.3 9.6 4.9 4.4 5.4 8.7 4.3 7.1 3.7 3.6 6.2 3.9 7.7 6.1 14.5 5.0 6.8 2.0 17.5 6.6 7.7 5.1 3.2 7.5 7.5 6.7 2.9 4.4 3.3 5.2 6.9 2.7 3.8 4.9 2.9 5.3 9.1 6.2 3.8 3.1 4.9 1.4 3.0 14.6 5.5 3.8 4.2 0.8 0.2 0.3 0.3 0.1 0.4 0.5 0.5 0.3 0.2 0.5 0.3 0.4 0.3 1.1 0.1 0.1 0.3 0.1 1.7 1.7 4.1 2.4 1.6 1.7 1.8 2.1 1.8 1.2 1.9 3.1 17.5 9.6 10.6 74.7 15.1 13.5 11.7 5.3 18.8 14.5 14.7 10.5 7.5 15.7 8.8 16.5 22.9 7.1 18.0 5.3 1.9 6.7 116.3 15.8 32.3 12.5 2.4 49.2 59.7 9.8 5.7 15.2 21.9 17.1 2.5 18.5 7.1 9.7 5.3 15.2 54.9 13.8 8.2 5.3 6.6 12.8 19.0 7.8 10.6 51.5 6.9 14.3 4.1 61.3 88.6 9.1 4.2 14.3 16.6 15.3 3.9 2.7 10.0 19.8 6.6 20.2 15.3 10.9 19.2 10.1 10.2 5.6 13.0 15.2 7.7 11.0 XPA "XP1, XPAC" ENSG00000136936 "XPA, DNA damage recognition and repair factor" P23025 9 97674909-97697340 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000155, HPA056856" Supported Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Cytokinetic bridge" "CAB000155: , HPA056856: AB_2683258" "unprognostic (8.76e-2)" "unprognostic (1.05e-3)" "unprognostic (1.60e-1)" "unprognostic (2.30e-2)" "unprognostic (4.17e-1)" "unprognostic (1.84e-1)" "unprognostic (5.26e-2)" "unprognostic (2.38e-1)" "unprognostic (3.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.97e-3)" "unprognostic (9.55e-3)" "prognostic favorable (4.28e-5)" "unprognostic (2.19e-2)" "unprognostic (1.56e-1)" "unprognostic (3.03e-2)" "unprognostic (1.17e-1)" 15.1 13.4 9.9 9.5 10.3 9.1 13.4 12.0 15.4 13.9 10.8 23.0 15.8 14.0 11.0 14.9 13.1 9.7 9.9 9.7 10.8 18.4 18.8 11.3 14.0 10.2 10.0 13.0 11.8 18.7 9.9 9.7 9.8 14.8 9.9 10.6 12.5 12.7 19.5 12.5 13.1 12.0 9.7 12.5 21.6 5.2 10.7 11.0 23.6 8.6 17.2 15.4 13.5 10.6 35.5 8.2 11.9 14.8 14.3 13.7 8.2 9.4 14.9 16.9 11.4 21.4 28.9 19.9 8.9 10.5 11.3 17.4 9.6 11.4 14.1 13.7 19.2 15.7 17.7 12.0 15.5 18.7 18.2 12.0 12.0 7.9 8.0 11.4 19.1 16.1 22.0 15.2 9.4 11.0 24.4 22.5 8.2 33.5 13.5 24.6 25.4 17.0 27.0 13.7 16.7 16.7 13.4 10.3 12.7 9.0 14.9 11.1 12.0 5.9 14.8 23.4 20.6 26.5 22.7 12.3 14.6 13.2 11.8 12.8 21.6 22.6 25.5 23.0 30.1 34.4 27.9 25.0 23.0 40.5 33.5 29.0 2.6 35.2 29.7 39.8 33.1 19.6 9.9 10.3 12.0 15.4 9.7 10.8 10.2 10.0 9.8 9.7 10.7 10.6 32.4 25.6 37.8 49.0 36.1 17.3 23.3 39.3 31.9 101.4 24.8 31.9 36.2 45.8 39.7 22.0 81.3 32.1 47.2 10.6 121.3 36.3 1.7 22.5 29.1 30.4 22.3 11.1 49.3 38.3 9.7 31.3 22.4 17.2 30.9 28.0 28.2 48.7 36.0 84.1 63.5 24.6 30.5 27.7 20.7 4.0 44.1 24.5 14.2 40.3 49.6 87.0 64.9 74.9 96.0 29.3 19.2 47.4 26.2 18.9 32.1 55.5 28.6 97.5 32.9 38.3 39.4 18.2 17.9 28.5 18.8 14.0 34.9 36.4 24.2 23.5 XPC "RAD4, XPCC" ENSG00000154767 "XPC complex subunit, DNA damage recognition and repair factor" Q01831 3 14145147-14178621 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009932, HPA035707, HPA069673" Supported Enhanced "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "CAB009932: AB_2241587, HPA035707: AB_2674743, HPA069673: AB_2686167" "unprognostic (7.46e-2)" "unprognostic (2.52e-2)" "unprognostic (4.50e-2)" "unprognostic (3.01e-1)" "unprognostic (6.63e-2)" "unprognostic (2.54e-2)" "unprognostic (1.97e-1)" "unprognostic (5.65e-2)" "unprognostic (1.50e-1)" "unprognostic (7.13e-3)" "unprognostic (4.39e-2)" "unprognostic (2.07e-1)" "prognostic favorable (4.14e-7)" "unprognostic (1.59e-1)" "unprognostic (7.88e-2)" "unprognostic (7.62e-2)" "prognostic favorable (2.46e-4)" 22.9 17.2 14.3 16.4 17.3 10.2 22.9 15.6 14.6 27.2 15.2 20.1 19.0 24.9 17.6 16.1 25.3 16.6 13.1 12.9 17.3 24.8 24.2 20.7 24.5 16.8 17.4 34.6 21.6 24.0 25.8 15.6 17.4 22.9 15.6 15.2 18.5 23.6 21.3 31.9 24.0 17.5 15.2 24.2 17.4 12.4 16.0 21.2 26.7 9.8 21.7 22.9 20.3 18.3 14.3 33.8 36.7 22.6 51.0 35.8 124.8 33.6 88.7 29.9 22.3 11.8 14.7 46.6 14.5 37.5 14.7 15.6 23.6 49.3 23.6 21.5 24.7 24.9 35.7 21.7 45.0 16.8 42.2 50.1 56.4 39.7 77.4 34.2 34.5 19.0 31.2 22.5 32.5 27.2 17.9 16.3 23.5 20.4 21.2 19.3 17.9 33.7 36.2 36.9 8.8 29.9 36.1 27.2 23.5 54.6 29.9 13.8 57.1 11.2 32.1 18.4 15.4 54.5 46.4 25.4 26.5 19.4 41.6 41.4 20.2 26.8 23.2 16.6 22.7 27.1 26.7 23.5 17.9 25.0 28.3 20.8 73.1 24.3 23.3 17.4 24.7 16.9 14.3 17.3 15.6 14.6 12.9 17.3 16.8 17.4 17.4 15.2 16.0 18.3 26.0 60.9 63.2 16.6 39.9 13.8 20.4 25.5 59.2 35.6 19.0 25.9 11.8 31.5 47.7 16.5 39.6 42.5 38.9 13.4 35.2 19.3 2.3 32.2 44.8 29.9 16.3 20.8 18.0 19.2 20.3 29.2 15.3 25.5 47.4 25.0 22.9 40.5 18.2 26.9 22.0 13.9 20.3 23.9 14.9 2.7 30.7 19.6 8.8 15.0 40.1 24.9 54.6 17.1 27.5 19.5 15.0 28.2 29.1 18.9 32.7 66.1 55.0 51.0 26.3 43.3 27.7 28.7 54.9 21.4 11.1 32.0 42.3 26.3 18.1 10.5 XPNPEP3 "APP3, ICP55, NPHPL1" ENSG00000196236 "X-prolyl aminopeptidase 3" Q9NQH7 22 40857077-40932815 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 232.9;Late spermatids: 306.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000527 Approved Supported Mitochondria,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Mitochondria Cytosol "HPA000527: AB_1079266" "prognostic unfavorable (8.19e-4)" "unprognostic (6.77e-2)" "unprognostic (3.22e-3)" "unprognostic (5.03e-3)" "unprognostic (6.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (2.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (6.69e-2)" "unprognostic (8.00e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (1.24e-1)" 2.7 4.9 6.4 1.3 6.3 1.6 2.6 8.3 7.8 2.9 7.1 2.5 14.6 4.7 5.0 2.8 3.7 4.4 5.3 7.8 6.1 3.7 8.2 2.4 2.5 7.2 6.6 3.8 3.6 2.1 3.7 1.5 6.6 2.8 2.2 4.4 3.4 2.5 5.5 5.5 10.1 2.4 5.6 2.8 2.8 3.7 6.7 5.9 3.2 3.5 1.9 3.7 2.8 9.0 2.7 4.1 2.5 5.5 6.3 4.6 2.1 3.3 2.5 1.7 1.7 3.1 1.6 5.2 1.8 6.5 7.8 7.3 4.7 2.4 2.7 3.5 9.7 3.3 9.7 7.5 3.2 6.0 0.5 4.0 3.9 5.7 3.3 2.7 3.3 3.8 2.9 4.8 4.3 4.1 3.1 3.2 1.5 5.0 8.3 3.9 3.3 3.0 5.9 3.6 2.3 1.9 3.9 4.8 3.3 2.6 6.1 2.7 3.2 3.6 3.4 3.4 2.1 4.7 4.0 7.4 5.6 8.5 2.5 2.8 2.5 2.9 2.1 2.5 1.0 3.7 1.2 1.2 1.9 1.9 2.4 1.9 3.6 0.7 6.9 3.8 1.9 2.8 6.4 6.3 8.3 7.8 7.8 6.1 7.2 6.6 6.6 5.6 6.7 9.0 9.6 6.4 17.6 32.0 12.7 13.3 8.0 15.6 9.6 16.0 12.9 13.2 22.5 15.7 14.0 9.2 18.8 21.7 11.0 6.2 15.6 12.2 232.9 37.5 16.6 11.7 13.8 12.0 22.0 17.1 18.7 13.1 12.2 12.0 14.0 17.8 10.8 36.0 14.7 16.8 24.0 9.5 12.2 12.6 15.7 306.8 19.9 11.9 17.8 18.7 7.8 13.0 9.2 19.6 42.3 10.4 9.5 15.4 11.8 7.8 3.5 25.3 38.5 19.8 32.9 14.0 12.7 65.6 34.2 12.2 16.3 20.0 11.0 19.5 8.7 7.6 XRCC4 ENSG00000152422 "X-ray repair cross complementing 4" Q13426 5 83077498-83353787 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 80.8;Pancreatic endocrine cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 61.6" "Low region specificity" "Detected in all" "HPA006801, HPA051538" Supported Enhanced Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "HPA006801: AB_1858899, HPA051538: AB_2681526" "prognostic unfavorable (1.80e-5)" "unprognostic (3.05e-2)" "unprognostic (5.12e-2)" "unprognostic (3.91e-3)" "unprognostic (1.55e-1)" "unprognostic (1.69e-1)" "unprognostic (1.44e-3)" "unprognostic (2.23e-2)" "unprognostic (2.19e-2)" "unprognostic (5.77e-2)" "unprognostic (2.38e-2)" "unprognostic (8.24e-2)" "unprognostic (4.46e-2)" "unprognostic (1.79e-1)" "unprognostic (1.97e-1)" "unprognostic (2.34e-1)" "unprognostic (6.91e-2)" 4.4 4.2 2.8 6.0 3.1 4.4 6.1 3.1 3.9 3.1 2.5 5.9 7.6 3.5 3.2 3.8 3.9 5.2 7.9 3.2 3.3 7.2 5.4 4.7 8.5 3.2 3.1 2.3 2.5 2.4 2.1 5.4 3.2 3.9 5.7 2.3 3.4 4.3 2.6 3.3 5.1 3.9 3.3 4.8 4.3 8.8 3.0 10.3 4.3 2.4 9.0 5.5 2.9 3.4 15.1 11.7 14.1 12.5 7.8 11.3 13.2 13.7 11.2 14.8 17.3 10.0 21.8 20.9 10.3 11.0 21.2 12.8 9.4 30.7 24.2 10.0 11.8 11.1 8.3 12.4 5.2 12.5 17.2 7.9 14.3 19.3 10.8 15.6 12.4 13.8 8.2 9.8 17.6 12.1 23.1 16.0 7.9 8.8 17.2 19.0 61.6 20.7 14.1 6.8 9.2 11.8 8.9 6.5 18.4 11.8 13.2 19.5 7.8 8.2 17.6 8.9 19.0 7.8 12.3 26.6 14.8 22.2 13.5 17.6 17.3 12.4 5.9 25.8 6.1 9.3 6.2 6.5 13.6 8.8 8.3 6.8 16.5 15.2 25.4 10.1 7.7 9.1 2.8 3.1 3.1 3.9 3.2 3.3 3.2 3.1 3.2 3.3 3.0 3.4 10.4 16.0 5.5 39.8 13.0 5.4 13.2 28.0 5.2 4.7 5.5 5.0 15.3 8.6 19.2 5.5 0.0 17.4 12.9 7.6 15.6 17.4 10.2 14.8 12.6 8.9 0.0 6.3 16.6 28.4 38.9 11.6 11.2 10.0 10.8 11.9 11.4 5.5 19.1 1.7 18.7 7.8 22.4 20.7 12.1 5.9 7.8 20.5 8.8 30.9 25.1 7.8 14.4 53.3 80.8 65.7 6.7 7.2 11.3 4.4 7.2 26.5 16.9 4.5 0.0 4.6 11.9 33.1 25.3 7.1 4.4 11.9 12.6 8.0 6.2 8.2 XYLT1 "PXYLT1, XT-I" ENSG00000103489 "Xylosyltransferase 1" Q86Y38 16 17101769-17470960 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 1194.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 4 "monocytes: 2.0" "Cell line enhanced" "Detected in many" "ASC diff: 55.1;ASC TERT1: 34.0;U-2197: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007478, HPA007966" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA 150000 "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "Endoplasmic reticulum" "HPA007478: AB_1080616, HPA007966: AB_1080618" "unprognostic (1.82e-1)" "unprognostic (7.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (9.12e-2)" "unprognostic (8.13e-2)" "unprognostic (9.40e-2)" "unprognostic (2.41e-3)" "unprognostic (2.82e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" 6.4 6.2 6.2 4.9 8.0 7.2 4.5 2.3 6.3 7.8 8.5 8.8 4.3 7.9 1.0 5.1 3.7 2.3 4.2 8.8 3.6 1.0 0.3 3.5 5.1 3.7 4.3 5.3 2.8 0.9 0.6 6.0 4.2 2.7 5.2 8.3 2.5 4.5 1.1 5.0 5.3 5.7 1.6 5.4 3.4 2.3 3.6 4.1 2.2 1.2 4.3 4.3 4.6 4.6 0.0 0.3 8.0 0.1 55.1 34.0 9.6 25.6 12.9 2.7 1.0 0.3 0.6 6.1 0.0 31.3 0.9 0.6 0.0 5.1 4.5 12.1 0.6 8.0 0.0 0.0 0.6 11.5 10.2 12.6 0.7 15.0 2.4 4.6 0.0 0.3 0.0 23.8 2.8 0.8 0.1 12.4 8.5 4.4 0.0 3.5 0.0 1.2 0.0 11.5 2.0 15.2 1.9 7.9 1.4 5.9 1.9 7.2 0.0 24.6 2.9 57.2 0.0 26.4 1.4 11.6 28.9 12.8 22.4 0.3 0.2 0.4 0.2 1.2 0.3 0.1 0.1 0.1 0.4 0.3 0.2 0.1 0.1 0.4 2.0 0.1 0.3 0.2 6.2 8.0 2.3 6.3 8.8 3.6 3.7 4.3 4.2 1.6 3.6 4.6 1.0 3.2 2.5 45.4 9.2 7.9 1.6 0.0 1.2 12.9 3.8 3.7 3.4 0.0 0.7 0.0 98.0 12.7 12.4 9.1 0.0 1.5 0.5 0.5 24.7 2.9 12.6 7.4 172.8 1.6 20.1 12.2 2.6 0.8 2.5 6.4 1.4 0.2 3.5 0.0 72.8 4.3 4.1 9.7 27.6 0.8 12.8 8.5 3.6 29.0 6.1 1.9 11.3 1194.8 63.0 4.0 7.4 50.0 6.2 5.3 6.1 0.2 0.0 4.4 6.6 7.9 5.9 0.3 1.6 4.1 18.5 13.1 7.7 8.1 6.9 6.4 XYLT2 "PXYLT2, XT-II" ENSG00000015532 "Xylosyltransferase 2" Q9H1B5 17 50346126-50363138 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "stomach 1: 86.7" "Group enriched" "Detected in many" 6 "Early spermatids: 316.4;Late spermatids: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 1100000 "Cluster 39: Non-specific - mRNA processing" "Cluster 4: Stomach - Digestion" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (1.52e-1)" "unprognostic (2.84e-1)" "unprognostic (1.65e-1)" "unprognostic (8.07e-2)" "unprognostic (1.90e-3)" "unprognostic (1.90e-1)" "unprognostic (7.29e-3)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (2.30e-1)" "unprognostic (1.54e-2)" "unprognostic (2.81e-1)" "unprognostic (7.63e-2)" "unprognostic (5.15e-2)" "unprognostic (7.38e-2)" "unprognostic (1.52e-2)" "unprognostic (2.68e-2)" 7.4 9.7 4.9 6.6 5.2 4.5 8.1 8.0 8.2 12.3 8.7 10.0 9.6 11.4 5.3 8.4 11.8 6.6 9.1 5.6 3.0 8.9 7.5 7.3 9.3 4.1 5.6 13.6 12.9 9.4 6.4 8.6 3.8 13.6 3.6 4.5 12.2 10.1 5.8 15.3 8.7 5.2 2.5 10.1 86.7 6.7 7.0 8.6 9.3 2.4 4.0 12.0 10.9 5.3 21.1 26.2 7.0 5.9 9.7 9.4 18.4 19.3 17.4 17.2 19.1 28.3 15.5 10.9 47.6 17.3 14.9 15.8 2.4 27.0 3.7 54.3 18.5 24.6 8.6 12.4 13.3 7.8 12.5 12.8 16.4 13.6 6.3 16.9 14.9 9.4 4.4 8.8 11.3 27.5 14.4 10.7 6.5 14.0 18.0 7.2 20.4 9.0 9.5 10.8 3.6 9.0 12.9 11.9 20.3 8.0 57.4 7.5 17.4 38.4 19.2 20.9 17.3 48.0 23.6 3.9 40.4 12.3 10.6 3.7 2.0 1.5 2.7 1.2 2.7 1.3 2.7 3.6 2.4 2.2 2.7 2.5 1.9 3.6 1.1 1.6 2.5 2.9 4.9 5.2 8.0 8.2 5.6 3.0 4.1 5.6 3.8 2.5 7.0 5.3 7.5 9.6 6.1 13.1 3.9 5.7 3.2 7.3 5.7 8.3 3.9 5.7 8.4 10.0 4.4 1.8 29.2 7.0 3.8 7.5 0.0 7.1 316.4 4.6 6.7 6.8 10.8 0.8 4.9 6.2 5.4 9.1 17.3 6.8 1.3 9.6 10.4 8.0 3.6 6.7 7.2 9.4 2.0 6.0 1.4 91.4 12.5 3.8 7.2 6.5 2.7 5.9 5.2 6.6 4.7 6.8 3.5 17.3 4.7 2.0 4.6 2.8 3.2 6.1 26.3 6.9 6.7 2.4 4.3 3.4 3.1 1.5 4.8 5.3 11.1 1.4 YAP1 YAP65 ENSG00000137693 "Yes1 associated transcriptional regulator" P46937 11 102110447-102233424 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 145.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009370, HPA038884, HPA038885, CAB069915, HPA070359" Enhanced Supported "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nucleoli, Cell Junctions" "CAB009370: AB_2273277, CAB069915: AB_922796, HPA038884: , HPA038885: AB_2676255, HPA070359: AB_2732154" "unprognostic (9.56e-2)" "unprognostic (6.75e-2)" "unprognostic (2.08e-1)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (3.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.28e-1)" "unprognostic (2.66e-3)" "unprognostic (3.73e-1)" "prognostic unfavorable (2.03e-4)" "unprognostic (9.26e-2)" "unprognostic (4.80e-2)" "unprognostic (8.38e-2)" "unprognostic (1.77e-1)" "unprognostic (1.04e-1)" "unprognostic (1.29e-2)" 57.2 27.8 19.1 25.9 19.1 0.3 42.7 18.6 17.1 62.5 44.3 41.5 27.2 78.1 45.9 74.7 65.6 49.3 48.1 15.9 22.1 39.3 33.5 45.7 13.0 31.8 30.2 93.1 22.3 37.0 9.9 83.1 21.8 59.2 30.1 12.9 40.6 83.7 48.3 44.2 27.4 100.5 27.3 14.7 31.6 15.0 27.0 13.8 85.9 58.2 22.7 60.9 52.6 20.2 56.9 52.1 141.5 69.6 151.1 143.1 118.7 130.4 147.8 124.2 101.5 130.2 134.9 0.0 105.4 171.6 92.1 98.0 71.0 186.4 130.6 16.8 25.5 0.1 67.3 89.5 115.3 0.1 2.5 115.2 119.4 136.6 220.2 138.4 39.4 6.7 0.0 0.1 142.1 27.2 2.6 0.4 66.8 135.9 49.3 0.1 79.7 0.3 90.9 99.5 0.4 4.7 153.6 57.2 43.5 129.1 103.2 0.8 43.4 175.4 68.8 89.6 55.7 0.1 0.2 0.8 51.0 0.2 130.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 19.1 18.6 17.1 15.9 22.1 31.8 30.2 21.8 27.3 27.0 20.2 28.4 35.3 69.4 145.3 1.5 113.7 47.8 43.5 71.2 0.4 48.1 43.8 39.2 62.9 37.2 92.0 0.0 91.4 0.4 16.2 11.7 27.6 6.7 61.8 53.3 28.9 7.3 0.0 1.5 18.3 20.3 49.0 23.9 85.1 0.0 127.2 26.0 45.2 10.6 0.0 1.6 13.1 14.2 1.6 21.5 4.6 37.9 2.2 44.4 60.0 1.0 27.6 0.0 5.0 0.7 25.2 16.3 40.6 0.1 66.0 27.2 26.1 41.6 1.2 39.5 21.6 62.0 2.5 5.3 59.5 123.2 61.6 2.1 15.9 27.8 65.6 YWHAE FLJ45465 ENSG00000108953 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon" P62258 17 1344275-1400222 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008445, CAB016200, CAB021109, CAB047350" Approved Supported Cytosol NA NA 83000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB016200: AB_626619, CAB021109: AB_10060396, CAB047350: , HPA008445: AB_1844336" "unprognostic (1.29e-1)" "unprognostic (1.50e-1)" "unprognostic (3.99e-2)" "prognostic favorable (6.48e-6)" "unprognostic (1.59e-1)" "unprognostic (2.91e-2)" "unprognostic (2.73e-2)" "unprognostic (4.77e-3)" "unprognostic (4.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.59e-1)" "unprognostic (2.73e-1)" "unprognostic (1.92e-3)" "unprognostic (8.33e-2)" "unprognostic (2.57e-1)" "unprognostic (3.24e-2)" "unprognostic (8.94e-2)" 221.9 198.9 251.8 122.8 264.2 121.3 198.7 266.3 272.8 168.8 195.7 161.1 136.8 155.6 192.7 239.1 188.1 103.7 242.3 260.7 275.4 229.3 211.7 176.9 113.7 271.1 246.8 170.8 154.9 236.9 178.8 198.2 267.1 150.0 168.1 220.8 184.8 121.6 656.7 193.3 129.3 137.3 279.2 101.5 136.9 165.4 262.2 211.0 208.5 441.8 164.5 186.9 179.7 302.7 615.3 565.8 700.2 563.4 376.9 454.7 589.8 382.1 481.5 724.5 571.3 907.5 305.5 524.7 411.9 621.9 439.7 463.1 859.2 745.6 798.7 294.2 930.9 334.1 366.2 409.4 483.4 277.1 311.1 421.6 458.6 619.3 897.0 520.6 729.2 458.5 402.8 337.9 719.7 368.5 445.8 264.1 566.6 596.9 332.7 477.3 255.9 380.4 547.7 365.7 354.2 497.2 531.1 240.3 364.3 439.9 442.3 290.9 467.4 411.9 293.8 453.7 731.4 190.5 329.9 346.6 478.4 387.5 585.4 78.6 137.2 41.2 47.3 153.6 57.8 78.1 67.3 55.1 180.3 59.1 55.7 51.2 49.9 64.1 144.8 133.8 99.7 151.0 251.8 264.2 266.3 272.8 260.7 275.4 271.1 246.8 267.1 279.2 262.2 302.7 363.6 298.1 194.4 83.2 161.1 573.9 457.5 468.4 281.7 153.6 313.6 219.1 473.4 265.9 310.9 371.5 50.1 463.2 128.7 300.7 745.4 460.8 258.0 573.6 414.3 352.6 352.6 244.7 73.4 421.4 709.5 319.4 194.7 502.7 211.5 328.1 262.3 309.0 384.9 111.0 72.4 346.3 376.4 260.9 434.9 434.3 280.8 227.5 425.2 60.0 320.5 357.8 55.6 56.8 112.1 464.8 289.8 294.9 279.5 487.9 272.1 707.8 504.6 173.3 243.3 361.2 524.6 508.7 573.3 333.8 586.6 519.5 130.7 287.2 361.1 474.4 YY1AP1 "HCCA2, YAP, YY1AP" ENSG00000163374 "YY1 associated protein 1" Q9H869 1 155659443-155689000 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA006986, HPA064249" Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Nucleoli fibrillar center" "HPA006986: AB_1080620, HPA064249: AB_2685226" "unprognostic (1.96e-2)" "unprognostic (2.80e-1)" "unprognostic (1.09e-2)" "unprognostic (5.67e-2)" "unprognostic (3.91e-2)" "unprognostic (1.77e-1)" "unprognostic (2.86e-3)" "unprognostic (1.23e-1)" "unprognostic (6.95e-2)" "unprognostic (8.13e-2)" "unprognostic (6.87e-2)" "unprognostic (8.65e-2)" "prognostic unfavorable (2.01e-6)" "unprognostic (6.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.39e-1)" "unprognostic (5.84e-2)" 41.9 36.1 35.4 28.1 38.6 77.2 42.8 51.1 41.6 47.1 20.7 56.6 23.5 41.5 38.6 53.0 44.2 26.7 48.1 33.5 32.7 42.3 38.3 49.3 38.6 32.6 35.2 47.5 37.6 35.4 47.1 32.0 32.4 46.3 35.6 41.3 41.0 37.6 113.8 54.0 39.7 42.6 31.7 47.9 41.8 74.6 38.8 50.4 39.9 73.2 49.8 45.8 45.8 41.3 63.5 32.0 40.3 45.9 44.9 40.4 86.5 39.9 58.0 70.4 59.9 49.3 65.7 50.1 38.4 58.6 35.8 60.5 61.3 55.7 66.2 46.7 30.5 41.6 36.2 31.2 47.5 66.7 54.2 43.0 56.1 53.7 68.5 48.8 44.3 47.5 55.8 69.9 52.2 56.0 68.5 32.4 63.7 86.5 46.4 53.7 34.9 80.4 42.7 45.5 40.3 47.8 52.6 75.0 51.5 72.5 82.3 108.7 36.0 39.4 34.6 41.4 53.5 87.7 62.8 123.2 38.9 43.0 46.4 40.3 27.6 50.3 34.7 27.5 36.8 26.7 29.6 36.4 34.0 20.9 25.5 25.5 29.5 45.0 27.7 15.9 40.1 35.1 35.4 38.6 51.1 41.6 33.5 32.7 32.6 35.2 32.4 31.7 38.8 41.3 18.3 19.2 26.7 28.7 26.0 34.7 30.5 20.2 38.7 24.5 27.4 21.3 23.2 22.8 22.9 12.9 43.8 23.6 24.5 25.7 13.7 17.3 68.0 20.0 21.8 24.5 34.9 42.9 33.8 19.1 27.9 24.7 25.0 25.5 25.3 16.6 15.7 23.1 21.5 16.8 34.8 23.8 12.2 20.8 36.3 81.0 28.0 28.5 19.6 37.5 27.4 20.8 15.5 38.7 48.3 18.4 16.2 25.6 36.9 29.2 22.5 11.7 17.3 24.9 6.6 24.9 22.3 77.6 25.5 38.8 35.7 45.0 26.7 26.6 24.4 33.8 ZBTB16 "PLZF, ZNF145" ENSG00000109906 "Zinc finger and BTB domain containing 16" Q05516 11 114059711-114256765 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 105.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 134.8;Inhibitory neurons: 125.9;NK-cells: 119.4;Skeletal myocytes: 163.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 23.3;MAIT T-cell: 39.4;naive B-cell: 11.0;NK-cell: 10.9" "Group enriched" "Detected in many" 5 "B-cells: 11.0;NK-cells: 10.9;T-cells: 39.4" "Cell line enhanced" "Detected in some" "ASC diff: 71.5;ASC TERT1: 38.6;HEL: 40.7;HHSteC: 26.6;HSkMC: 26.7;hTCEpi: 30.6;hTERT-HME1: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001499, CAB004540" Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB004540: AB_2218941, HPA001499: AB_1079640" "unprognostic (2.21e-1)" "unprognostic (2.17e-1)" "unprognostic (7.30e-2)" "unprognostic (1.18e-1)" "unprognostic (2.53e-1)" "unprognostic (3.05e-1)" "unprognostic (1.25e-2)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (8.79e-4)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "prognostic favorable (2.21e-4)" "unprognostic (2.57e-3)" "unprognostic (2.67e-1)" "unprognostic (1.00e-1)" "unprognostic (5.90e-2)" 55.8 20.8 5.1 3.4 14.9 7.6 32.3 11.7 24.8 25.9 17.7 20.9 0.9 29.6 4.0 28.1 30.9 13.1 28.1 9.9 8.4 10.6 14.5 27.1 8.8 20.1 8.4 51.4 61.7 34.3 6.4 9.6 15.2 15.1 3.3 2.2 13.3 7.0 88.6 28.5 16.3 15.8 4.9 13.2 18.3 4.0 7.1 6.5 29.3 105.8 2.0 29.4 19.7 18.0 0.0 0.0 13.0 0.0 71.5 38.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 40.7 0.0 0.0 26.6 0.9 0.7 26.7 30.6 0.0 25.6 0.0 4.6 5.5 0.1 0.0 0.8 0.0 2.2 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 4.2 1.2 23.3 1.2 39.4 0.4 1.2 3.5 0.1 11.0 1.3 0.6 0.3 10.9 1.2 0.0 0.4 5.7 5.1 14.9 11.7 24.8 9.9 8.4 20.1 8.4 15.2 4.9 7.1 18.0 95.3 22.4 7.7 59.1 16.3 11.1 81.7 7.7 8.6 32.6 12.6 16.8 35.1 42.9 7.1 9.2 0.0 0.1 51.2 0.7 1.9 1.9 21.1 1.7 41.3 49.5 7.2 18.1 134.8 0.9 0.2 59.8 1.1 3.8 14.5 38.2 65.7 50.9 0.8 0.0 125.9 3.7 8.2 27.0 5.3 27.7 89.8 32.1 7.2 65.6 7.6 20.2 119.4 45.8 43.4 0.3 0.1 92.2 17.7 38.6 28.8 6.6 6.8 1.9 105.2 163.9 75.3 0.4 9.9 1.8 6.8 0.3 27.8 0.2 3.5 9.4 ZBTB20 "DKFZp566F123, DPZF, ODA-8S, ZNF288" ENSG00000181722 "Zinc finger and BTB domain containing 20" Q9HC78 3 114314500-115147288 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 66.5" "Cell type enhanced" "Detected in many" "Astrocytes: 1998.0;Microglial cells: 855.4;Oligodendrocyte precursor cells: 1908.5;Oligodendrocytes: 2090.4" "Cancer enhanced" "Detected in some" "stomach cancer: 1.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015551, HPA016815" Approved Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 43: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear bodies" "HPA015551: AB_2669217, HPA016815: AB_1858947" "unprognostic (1.79e-1)" "unprognostic (1.50e-2)" "unprognostic (5.51e-2)" "unprognostic (2.33e-3)" "unprognostic (5.72e-3)" "unprognostic (3.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (1.13e-1)" "unprognostic (2.68e-1)" "unprognostic (7.51e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-3)" "unprognostic (6.94e-2)" "unprognostic (1.41e-1)" "unprognostic (7.83e-3)" "unprognostic (1.81e-1)" 4.1 3.9 24.5 1.1 43.8 2.5 3.4 66.5 43.7 3.4 5.7 1.7 0.8 3.6 9.6 1.2 2.4 2.3 3.5 65.9 30.9 5.2 5.4 1.8 1.8 43.8 42.6 6.8 3.4 2.3 1.4 1.0 32.9 5.4 1.4 8.5 3.0 4.9 7.9 2.3 0.8 2.9 29.9 2.5 1.7 15.8 39.4 1.9 5.0 8.9 1.7 1.6 0.7 41.1 1.4 2.7 1.0 2.8 4.2 1.8 0.0 1.3 2.5 0.8 0.6 1.7 0.5 0.4 3.7 3.2 0.8 0.0 4.0 0.6 0.7 0.3 0.1 0.4 1.7 1.3 0.8 0.1 0.0 1.8 0.2 1.4 0.4 2.4 0.8 0.2 0.1 0.6 4.4 0.0 0.1 0.1 0.3 0.0 0.1 0.1 3.4 0.0 2.9 0.0 0.3 0.7 0.5 0.0 0.9 0.1 0.0 0.3 4.8 1.0 3.5 0.2 1.8 0.9 0.0 0.1 1.7 0.2 1.3 9.7 1.5 6.4 6.8 2.3 4.6 20.4 6.4 6.4 1.9 11.3 8.3 6.8 3.5 5.3 4.6 4.9 3.6 3.5 24.5 43.8 66.5 43.7 65.9 30.9 43.8 42.6 32.9 29.9 39.4 41.1 278.1 160.3 122.6 1998.0 115.4 25.7 38.2 11.3 22.2 123.6 103.7 81.8 48.5 108.7 25.2 294.3 60.5 0.2 56.1 10.3 49.0 231.4 450.3 109.8 628.3 106.4 31.8 20.4 72.3 82.9 0.6 174.5 36.7 170.5 80.6 194.5 56.0 106.0 4.3 80.8 462.3 14.5 40.7 20.4 28.5 111.1 105.6 36.0 32.0 855.4 29.3 127.7 36.0 1908.5 2090.4 107.8 10.5 120.7 58.4 28.0 19.2 198.4 36.4 108.6 85.5 301.2 124.6 6.9 8.7 14.2 18.5 0.5 67.4 140.7 17.2 25.0 ZBTB42 ZNF925 ENSG00000179627 "Zinc finger and BTB domain containing 42" B2RXF5 14 104800596-104804712 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 11.7;Exocrine glandular cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "eosinophil: 5.4" "Lineage enriched" "Detected in single" 10 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "HDLM-2: 19.3;MCF7: 33.7;T-47d: 26.9" "Not detected" "Not detected" HPA066961 Approved Supported Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA066961: AB_2685756" "unprognostic (1.23e-1)" "unprognostic (1.84e-1)" "unprognostic (8.68e-2)" "unprognostic (1.59e-1)" "unprognostic (6.99e-2)" "unprognostic (6.67e-2)" "unprognostic (6.17e-3)" "unprognostic (2.56e-1)" "unprognostic (4.35e-1)" "unprognostic (2.70e-2)" "unprognostic (1.63e-1)" "unprognostic (3.42e-1)" "prognostic favorable (2.30e-9)" "unprognostic (1.34e-1)" "unprognostic (2.75e-1)" "unprognostic (1.58e-3)" "unprognostic (5.45e-2)" 2.3 3.5 1.1 1.7 1.1 0.3 3.3 1.0 0.9 1.7 1.5 3.0 3.2 2.2 1.8 4.8 4.5 1.8 4.5 0.9 1.2 4.1 5.5 4.3 1.4 1.8 1.4 1.1 11.5 2.2 1.0 1.1 1.3 6.2 1.8 0.4 6.3 3.3 6.5 2.6 2.9 1.4 1.4 2.2 6.5 2.4 1.2 1.4 4.7 2.6 1.3 2.3 2.2 1.0 1.3 4.4 1.3 5.3 1.0 1.1 5.4 1.9 2.0 3.4 3.0 2.8 5.1 0.4 3.7 1.9 2.3 5.8 1.1 1.8 0.5 19.3 1.3 1.8 2.3 3.3 1.6 0.4 10.3 2.0 2.1 1.4 0.7 2.4 1.5 3.8 3.0 2.9 0.6 33.7 3.6 2.8 0.8 8.9 4.0 5.0 0.3 2.7 2.5 8.6 5.9 2.5 1.5 7.9 3.4 1.2 26.9 2.1 2.4 1.3 3.0 0.3 0.6 3.1 1.8 0.3 4.3 1.8 2.8 0.0 0.1 5.4 0.3 0.0 0.5 0.4 0.4 0.1 0.0 0.4 0.3 0.4 0.0 0.1 0.0 0.4 0.3 0.2 1.1 1.1 1.0 0.9 0.9 1.2 1.8 1.4 1.3 1.4 1.2 1.0 3.1 3.2 11.7 0.3 1.2 0.4 5.0 1.9 1.2 0.3 8.1 3.4 4.4 5.7 8.2 0.0 0.0 1.2 1.1 4.3 3.9 4.2 2.6 2.3 1.2 2.6 5.4 4.4 0.0 13.5 1.9 1.1 3.1 3.9 0.0 2.3 2.5 7.3 1.1 0.0 0.0 6.4 2.0 2.5 0.6 0.9 0.6 0.9 1.8 0.0 0.8 2.8 5.2 0.5 0.0 7.5 3.2 0.4 0.7 6.9 3.4 4.3 3.1 0.4 0.0 1.5 1.6 8.4 3.4 3.4 0.1 0.8 1.8 0.5 4.9 5.1 ZEB2 "KIAA0569, SIP-1, SIP1, ZFHX1B" ENSG00000169554 "Zinc finger E-box binding homeobox 2" O60315 2 144364364-144521057 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Epilepsy, Hirschsprung disease, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 363.7" "Cell type enhanced" "Detected in many" "Horizontal cells: 662.9;Inhibitory neurons: 539.3;Oligodendrocytes: 1489.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 154.0;THP-1: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003456 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoli "Nucleoplasm, Cytosol" "HPA003456: AB_10603840" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" "unprognostic (2.42e-1)" "unprognostic (4.12e-1)" "unprognostic (4.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.77e-2)" "unprognostic (5.83e-2)" "unprognostic (7.90e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (6.04e-5)" "unprognostic (1.11e-2)" "unprognostic (1.73e-2)" "unprognostic (7.45e-2)" "unprognostic (1.32e-2)" 61.3 45.2 185.6 56.8 258.3 127.5 29.5 138.3 165.5 52.4 3.0 24.5 21.9 29.6 9.6 27.9 20.3 43.9 45.7 132.5 155.4 18.2 23.3 41.2 43.2 238.3 214.5 70.5 5.7 6.7 3.3 62.1 222.8 18.5 29.9 35.5 9.6 22.7 20.8 12.8 25.9 33.3 183.2 69.4 18.0 16.2 249.6 10.6 13.3 18.8 24.2 46.6 24.1 363.7 1.6 2.0 83.4 0.1 98.9 49.7 0.3 35.1 35.1 38.5 37.1 0.0 0.8 6.6 0.1 37.4 10.6 0.4 14.5 0.1 47.6 37.6 11.2 154.0 6.3 0.2 23.0 26.4 113.2 42.1 0.9 48.9 22.9 33.7 29.4 0.0 43.0 4.1 45.2 0.2 0.4 79.9 12.3 0.0 1.9 44.1 63.5 0.2 0.4 0.6 0.7 22.1 4.2 0.2 97.3 27.5 0.2 181.4 45.9 42.9 0.7 87.5 11.0 47.1 0.3 7.5 66.7 78.4 122.6 27.8 47.7 12.2 21.0 42.6 1.9 9.2 2.7 10.7 27.0 9.4 1.9 7.7 15.2 7.3 43.9 21.5 0.6 19.0 185.6 258.3 138.3 165.5 132.5 155.4 238.3 214.5 222.8 183.2 249.6 363.7 32.6 6.4 19.2 121.8 92.4 24.9 1.2 0.6 3.4 158.6 2.2 4.3 71.0 1.5 10.1 5.5 4.2 1.7 426.2 0.1 1.9 0.7 2.2 2.1 84.7 29.2 0.0 127.0 228.2 0.8 2.0 123.0 13.3 2.5 157.5 99.3 79.2 4.6 144.5 662.9 539.3 0.0 0.0 435.0 276.3 7.2 120.5 435.0 103.2 343.8 233.6 69.3 223.5 381.0 1489.6 0.2 1.1 66.5 132.3 1.8 0.0 10.3 4.0 11.9 184.1 185.0 198.7 2.9 11.3 3.4 19.6 4.7 136.7 108.8 0.4 2.2 ZFPM2 "FOG2, hFOG-2, ZC2HC11B, ZNF89B" ENSG00000169946 "Zinc finger protein, FOG family member 2" Q8WW38 8 104590733-105804539 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Gonadal differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.2;ovary: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 115.2;Excitatory neurons: 524.4;Inhibitory neurons: 159.8;Microglial cells: 152.7;Oligodendrocyte precursor cells: 689.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 64.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.4;BJ hTERT+: 14.2;HHSteC: 9.9;hTEC/SVTERT24-B: 5.7;HUVEC TERT2: 10.9;K-562: 6.0;TIME: 6.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 39.4" HPA004094 Approved Supported Nucleoplasm NA NA "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA004094: AB_1859058" "unprognostic (4.48e-2)" "unprognostic (3.24e-2)" "unprognostic (7.77e-3)" "unprognostic (1.36e-2)" "unprognostic (3.51e-1)" "unprognostic (1.53e-1)" "unprognostic (8.37e-2)" "unprognostic (8.35e-3)" "unprognostic (1.97e-2)" "unprognostic (1.04e-1)" "unprognostic (1.97e-1)" "unprognostic (5.74e-2)" "unprognostic (1.69e-6)" "unprognostic (4.10e-3)" "unprognostic (5.41e-2)" "unprognostic (1.63e-4)" "unprognostic (2.61e-2)" 12.2 2.8 7.4 1.5 3.1 0.0 4.5 64.2 12.7 6.5 0.0 4.3 0.5 10.7 2.3 4.5 12.3 5.8 10.2 16.4 3.5 1.1 2.7 3.8 2.7 11.9 5.7 33.3 0.7 0.4 1.1 4.2 12.3 0.9 2.1 1.1 1.0 1.9 18.0 1.6 1.9 17.8 0.2 2.9 2.8 4.3 6.3 1.3 6.8 17.2 1.5 7.0 4.9 3.4 0.0 0.0 6.4 0.0 5.4 1.7 0.0 0.5 14.2 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.0 0.0 4.9 1.6 0.0 0.0 9.9 0.0 0.0 0.5 0.0 5.7 0.0 1.9 10.9 0.0 6.0 0.0 1.3 0.0 1.4 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.4 4.3 0.0 6.5 0.3 0.9 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 3.1 64.2 12.7 16.4 3.5 11.9 5.7 12.3 0.2 6.3 3.4 10.0 0.0 0.6 115.2 0.1 3.6 0.3 0.0 0.6 2.9 0.1 0.3 21.3 0.0 1.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 55.2 0.6 9.8 7.9 0.0 0.0 524.4 0.0 0.1 17.1 1.1 1.5 0.0 24.6 7.1 0.0 0.3 8.4 159.8 0.2 0.0 0.0 1.7 34.0 23.9 0.3 1.8 152.7 0.6 0.1 0.0 689.7 10.0 0.1 0.0 13.5 0.0 0.6 0.0 0.0 0.0 0.7 6.6 22.5 8.1 0.9 2.2 0.1 2.8 0.4 0.2 1.4 0.2 0.4 ZIC1 "ZIC, ZNF201" ENSG00000152977 "Zic family member 1" Q15915 3 147393422-147510293 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Craniosynostosis, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 616.8" "Group enriched" "Detected in some" 4 "Microglial cells: 25.3;Skeletal myocytes: 61.0" "Cancer enhanced" "Detected in many" "glioma: 9.5" "Region enriched" "Detected in all" 5 "cerebellum: 616.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 174.0;MCF7: 43.9;U-2197: 28.5" "Region enhanced" "Detected in all" "cerebellum: 207.4" "Region enriched" "Detected in all" 8 "cerebellum: 638.1" HPA004098 Supported Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA004098: AB_1859065" "unprognostic (1.33e-2)" "unprognostic (1.82e-1)" "unprognostic (4.01e-2)" "unprognostic (2.36e-1)" "unprognostic (9.32e-2)" "unprognostic (1.52e-2)" "unprognostic (1.68e-2)" "unprognostic (2.19e-1)" "unprognostic (5.01e-1)" "unprognostic (2.61e-7)" "unprognostic (2.95e-3)" "unprognostic (1.67e-2)" "unprognostic (3.01e-1)" 3.4 0.7 25.0 0.0 50.7 0.0 0.2 616.8 30.3 0.0 39.0 0.1 0.2 0.0 1.8 0.2 0.0 0.1 0.1 13.6 39.5 0.1 12.8 0.1 0.1 66.8 55.3 0.2 0.1 0.0 2.4 0.0 67.3 0.0 0.1 10.7 0.5 0.0 6.9 2.5 0.8 0.0 23.8 0.0 0.2 0.3 112.1 0.0 0.0 0.8 0.0 0.0 0.0 44.8 0.0 0.0 174.0 0.0 17.9 19.6 9.8 11.4 13.5 12.1 9.9 0.0 0.0 0.0 9.1 0.9 9.2 0.0 0.1 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.4 0.0 0.7 0.0 0.0 3.1 0.0 10.9 43.9 0.0 0.0 0.5 0.9 0.0 0.0 17.1 0.0 0.0 0.0 0.0 8.1 0.0 0.0 10.7 0.0 0.0 0.0 0.0 17.9 0.0 28.5 11.0 0.0 0.0 0.0 13.5 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 50.7 616.8 30.3 13.6 39.5 66.8 55.3 67.3 23.8 112.1 44.8 0.2 0.0 0.0 8.5 0.0 0.1 0.0 0.0 0.0 0.3 0.9 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.1 0.0 25.3 0.0 4.3 0.0 2.0 9.5 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 61.0 0.3 0.4 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 ZIC2 HPE5 ENSG00000043355 "Zic family member 2" O95409 13 99981784-99986765 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "brain: 123.4;choroid plexus: 35.2" "Cell type enhanced" "Detected in some" "Astrocytes: 28.1;Cone photoreceptor cells: 6.2;Microglial cells: 29.0;Muller glia cells: 10.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 123.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 86.2;HDLM-2: 43.5;HEK 293: 66.1;NTERA-2: 80.5;SCLC-21H: 179.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 113.3" HPA055031 Supported "Nuclear bodies" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear bodies" "HPA055031: AB_2682676" "unprognostic (6.43e-6)" "prognostic favorable (2.64e-4)" "unprognostic (5.73e-2)" "unprognostic (1.99e-2)" "unprognostic (4.39e-1)" "unprognostic (3.12e-2)" "prognostic unfavorable (2.91e-4)" "unprognostic (4.66e-2)" "unprognostic (3.10e-1)" "unprognostic (1.59e-1)" "unprognostic (9.36e-3)" "unprognostic (7.42e-2)" "unprognostic (0.00e+0)" "unprognostic (3.26e-1)" "unprognostic (2.11e-1)" "unprognostic (5.36e-3)" 0.0 0.2 17.0 0.0 19.0 0.0 0.0 123.4 16.2 0.0 35.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 16.0 10.4 0.1 0.0 0.0 0.0 20.9 14.8 0.0 0.0 0.0 1.2 0.0 22.5 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 8.8 0.0 0.0 1.2 27.1 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.5 4.9 86.2 5.5 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.5 5.8 0.0 7.3 0.0 4.6 0.1 3.9 0.0 0.0 43.5 66.1 6.4 4.0 4.4 0.0 0.0 4.3 0.0 6.2 0.0 3.9 0.4 0.0 2.2 6.5 0.0 0.0 2.9 0.4 34.3 80.5 0.0 2.0 19.8 3.3 0.1 0.4 2.2 179.7 0.0 2.8 0.5 0.0 3.3 4.2 33.5 0.0 20.2 0.0 3.6 5.8 0.6 0.0 0.0 4.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 19.0 123.4 16.2 16.0 10.4 20.9 14.8 22.5 8.8 27.1 11.3 0.2 0.0 0.0 28.1 0.0 0.0 0.0 0.0 0.6 0.3 0.2 0.3 0.7 0.0 0.0 1.8 6.2 0.0 0.0 0.7 0.0 0.0 0.4 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 29.0 0.0 10.3 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 1.5 0.6 0.4 0.1 0.0 0.0 0.0 0.0 0.0 ZIC3 "HTX, HTX1, ZNF203" ENSG00000156925 "Zic family member 3" O60481 X 137566127-137577691 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.8;choroid plexus: 4.0;retina: 2.7" "Cell type enhanced" "Detected in some" "Microglial cells: 4.7;Muller glia cells: 9.6;Rod photoreceptor cells: 1.3;Spermatocytes: 2.0;Spermatogonia: 3.7" "Cancer enriched" "Detected in single" 14 "testis cancer: 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 35 "AF22: 38.8;NTERA-2: 42.8;SuSa: 24.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052936, HPA069523" Uncertain Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA052936: AB_2681993, HPA069523: AB_2732136" "unprognostic (3.55e-5)" "unprognostic (3.82e-1)" "unprognostic (1.95e-1)" "unprognostic (3.31e-1)" 0.0 0.0 2.9 0.0 3.9 0.1 0.0 13.8 3.5 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 4.5 0.0 0.0 0.0 0.0 3.5 3.7 0.0 0.0 0.0 0.7 0.0 4.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.6 4.3 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.1 42.8 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 24.8 0.6 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 3.9 13.8 3.5 1.8 4.5 3.5 3.7 4.0 2.3 4.3 3.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 4.7 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 2.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZIC4 ENSG00000174963 "Zic family member 4" Q8N9L1 3 147386046-147406809 "Human disease related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 68.5" "Cell type enhanced" "Detected in some" "Early spermatids: 5.0;Late spermatids: 13.5;Microglial cells: 6.5;Muller glia cells: 5.5;Oligodendrocytes: 6.9;Skeletal myocytes: 6.2" "Cancer enhanced" "Detected in some" "glioma: 0.8" "Region enriched" "Detected in all" 4 "cerebellum: 68.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 16.5;ASC diff: 4.7;BEWO: 3.5;MCF7: 4.7;SH-SY5Y: 4.9;U-2197: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 8 "cerebellum: 67.3" HPA030194 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA030194: AB_2673367" "unprognostic (1.12e-1)" "unprognostic (9.95e-2)" "unprognostic (5.59e-3)" "unprognostic (1.02e-1)" "unprognostic (6.83e-2)" "unprognostic (1.10e-1)" "unprognostic (2.20e-1)" "unprognostic (9.13e-2)" "unprognostic (1.10e-10)" "unprognostic (3.50e-2)" "unprognostic (8.69e-2)" 0.6 0.0 1.9 0.0 6.6 0.0 0.0 68.5 4.7 0.0 5.5 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.7 5.5 0.0 0.3 0.0 0.0 10.6 5.8 0.0 0.0 0.0 0.1 0.0 9.0 0.0 0.0 4.8 0.0 0.0 1.3 1.2 0.1 0.0 2.7 0.0 0.0 0.5 10.5 0.0 0.0 0.0 0.0 0.0 0.0 15.3 0.0 0.0 16.5 0.0 4.7 1.9 3.5 1.8 0.4 0.2 0.5 0.0 0.0 0.0 2.1 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.4 4.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 4.9 0.0 0.0 2.1 0.0 0.0 0.0 0.0 1.1 0.0 3.9 1.8 0.0 0.0 0.0 1.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 6.6 68.5 4.7 1.7 5.5 10.6 5.8 9.0 2.7 10.5 15.3 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 6.5 0.0 5.5 0.0 0.5 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 6.2 0.1 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZMPSTE24 "FACE-1, HGPS, PRO1, STE24, Ste24p" ENSG00000084073 "Zinc metallopeptidase STE24" O75844 1 40258041-40294180 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006988 Approved NA NA 50000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 1: Thyroid gland - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "HPA006988: AB_1080659" "unprognostic (6.32e-2)" "unprognostic (1.63e-2)" "unprognostic (3.75e-3)" "unprognostic (4.63e-2)" "unprognostic (4.16e-3)" "unprognostic (1.37e-1)" "prognostic unfavorable (5.73e-6)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (1.84e-3)" "unprognostic (4.78e-2)" "unprognostic (7.96e-2)" "unprognostic (5.06e-2)" "unprognostic (3.65e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (6.34e-4)" "unprognostic (2.71e-2)" 20.5 24.6 16.3 19.9 16.7 5.6 25.5 18.1 22.9 26.2 21.9 28.5 22.2 26.7 27.4 21.7 18.8 25.7 20.6 16.1 18.8 46.0 38.4 21.7 16.8 17.4 17.7 14.3 17.4 53.3 10.2 22.1 18.5 26.3 33.1 10.9 19.6 23.8 16.3 16.3 23.4 32.2 18.7 13.7 21.3 11.0 17.7 15.5 27.5 18.1 23.0 29.4 16.2 18.9 69.3 38.4 35.6 26.1 90.3 71.3 67.0 64.0 60.6 81.7 73.9 35.4 118.8 62.7 41.1 92.1 29.9 71.0 78.4 67.9 97.9 54.4 39.8 59.9 36.0 44.5 45.4 99.3 68.8 45.5 67.4 64.7 28.4 45.4 58.3 27.3 63.0 60.6 80.1 30.2 60.7 28.3 70.0 47.2 42.2 52.2 60.2 77.6 75.2 58.0 38.0 44.6 60.9 155.6 85.9 56.3 55.2 249.1 46.4 68.6 52.5 56.0 78.0 37.1 106.2 49.6 75.6 64.6 79.1 18.9 21.4 14.0 17.6 27.2 22.5 15.0 19.4 19.4 29.4 11.4 16.7 22.9 8.5 29.6 24.3 18.4 24.6 22.7 16.3 16.7 18.1 22.9 16.1 18.8 17.4 17.7 18.5 18.7 17.7 18.9 28.9 38.5 24.1 19.2 20.1 32.0 24.2 41.4 33.0 6.6 35.9 19.0 25.5 54.3 43.0 73.5 0.0 41.4 22.1 44.3 31.3 58.9 3.5 30.7 32.6 31.2 27.6 18.1 16.6 36.9 38.3 36.0 21.9 40.0 21.0 16.6 27.5 64.4 34.0 10.1 13.9 31.0 54.9 33.9 24.5 2.2 28.6 28.6 24.9 11.2 30.5 29.3 19.6 17.6 20.2 44.0 29.3 32.7 31.1 37.7 31.7 42.6 64.2 7.7 0.0 26.8 41.2 7.8 6.4 31.5 27.1 39.0 23.1 28.9 35.6 24.5 ZNF141 "D4S90, pHZ-44" ENSG00000131127 "Zinc finger protein 141" Q15928 4 337814-384868 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" "unprognostic (1.21e-1)" "unprognostic (6.88e-3)" "unprognostic (4.64e-2)" "unprognostic (2.60e-2)" "unprognostic (2.59e-2)" "unprognostic (1.44e-2)" "unprognostic (1.47e-1)" "unprognostic (3.09e-2)" "unprognostic (4.45e-3)" "unprognostic (1.11e-1)" "unprognostic (5.02e-2)" "unprognostic (1.47e-3)" "unprognostic (2.71e-1)" "unprognostic (1.66e-2)" "prognostic favorable (4.76e-4)" 4.7 13.9 8.6 3.3 9.1 1.3 4.8 12.5 12.1 8.8 9.1 5.3 2.4 5.1 4.2 4.2 6.9 1.5 5.1 8.9 8.6 6.1 6.1 6.5 5.1 8.1 8.2 15.6 5.5 3.2 8.5 2.3 8.3 7.6 2.5 13.7 5.9 2.5 2.5 4.8 6.2 1.2 7.6 7.1 4.4 5.6 8.5 3.3 7.5 1.1 4.3 5.5 6.7 9.2 0.1 1.3 5.0 2.0 1.4 1.9 1.3 1.5 0.9 2.1 3.0 4.4 2.6 0.3 1.2 1.2 2.5 2.1 0.0 1.2 2.8 0.0 1.2 0.1 2.3 0.2 1.0 0.1 4.8 2.2 1.3 2.1 0.9 1.1 0.5 1.0 0.1 0.2 2.1 1.4 4.3 6.3 5.4 0.5 2.3 0.1 0.0 0.5 1.5 2.7 5.0 2.5 1.8 0.7 1.3 2.6 2.2 4.8 0.4 0.3 1.6 1.2 1.5 0.1 0.2 0.2 0.0 0.0 0.9 0.5 0.5 1.0 1.3 0.6 1.3 1.2 1.1 1.1 1.0 1.8 1.6 1.3 0.9 1.4 0.9 0.7 0.9 0.5 8.6 9.1 12.5 12.1 8.9 8.6 8.1 8.2 8.3 7.6 8.5 9.2 9.5 6.4 7.7 14.7 28.3 3.7 3.3 2.0 6.2 24.0 5.2 5.8 5.3 8.6 4.2 14.7 14.6 3.5 11.2 2.6 5.9 3.5 7.9 4.5 9.3 9.6 6.0 8.4 9.9 2.9 3.0 9.7 4.6 5.6 5.7 22.8 3.9 2.0 2.3 33.7 11.6 2.7 2.0 2.2 6.0 6.1 11.1 12.2 3.6 15.0 5.5 7.9 16.5 15.1 16.3 2.9 1.0 6.0 7.2 2.8 3.3 1.7 4.8 18.1 26.3 9.8 21.3 10.6 9.7 3.3 4.1 4.1 13.5 15.3 4.5 2.2 ZNF148 "BERF-1, BFCOL1, HT-BETA, pHZ-52, ZBP-89, ZFP148" ENSG00000163848 "Zinc finger protein 148" Q9UQR1 3 125225669-125375325 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001656, CAB017486" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Golgi apparatus" "CAB017486: AB_794260, HPA001656: AB_1079995" "unprognostic (2.40e-1)" "unprognostic (1.12e-2)" "unprognostic (5.03e-2)" "unprognostic (3.94e-2)" "unprognostic (5.94e-3)" "unprognostic (5.66e-2)" "unprognostic (1.24e-2)" "unprognostic (2.36e-1)" "unprognostic (1.69e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (2.88e-4)" "unprognostic (6.36e-2)" "unprognostic (7.97e-3)" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (3.63e-2)" "unprognostic (2.72e-1)" 8.9 7.5 5.6 9.4 8.9 7.9 12.1 12.9 7.8 12.6 0.0 10.8 7.6 13.9 10.2 10.3 12.4 9.5 15.5 4.5 16.4 12.9 11.7 10.3 12.3 4.2 6.5 17.4 9.5 15.8 4.7 9.7 4.2 11.1 11.5 13.1 10.0 11.1 11.1 5.8 8.9 13.7 2.3 11.9 9.8 10.5 14.5 16.9 30.0 12.0 14.4 10.6 6.1 8.3 30.6 19.8 21.1 18.9 18.4 19.7 16.0 27.2 31.5 29.9 28.4 19.1 16.6 24.4 18.5 40.3 24.1 24.4 23.2 20.5 42.4 10.9 8.9 30.1 23.3 9.8 13.6 20.9 29.1 16.1 21.0 28.0 29.4 19.7 20.7 17.7 15.0 20.2 22.3 23.9 26.1 7.7 13.6 20.6 16.8 18.6 23.2 13.9 17.1 33.6 18.2 15.3 36.2 18.2 29.7 11.7 22.7 20.8 26.6 22.6 24.1 28.5 17.5 17.4 21.5 36.6 16.9 13.1 21.3 4.4 15.3 32.0 21.8 14.5 22.5 24.5 19.2 20.9 13.0 22.2 27.9 22.0 51.4 33.2 23.4 11.3 19.6 20.1 5.6 8.9 12.9 7.8 4.5 16.4 4.2 6.5 4.2 2.3 14.5 8.3 54.7 93.0 41.3 92.7 56.7 35.6 26.0 36.2 48.9 68.0 37.0 35.7 75.2 24.3 43.0 33.1 39.6 28.7 53.7 34.7 25.4 37.5 82.0 28.8 54.3 51.6 47.9 32.0 166.7 37.4 24.3 44.5 31.1 38.1 50.6 75.7 37.9 41.0 31.1 75.7 170.3 34.4 26.4 37.1 21.2 135.2 48.1 41.2 17.8 143.4 50.1 45.7 59.8 154.3 151.4 33.7 25.6 59.0 35.8 36.6 28.2 43.9 27.5 39.4 32.9 63.4 60.7 24.4 24.2 32.5 38.4 31.6 52.0 42.0 33.6 35.6 ZNF335 "bA465L10.2, NIF-1" ENSG00000198026 "Zinc finger protein 335" Q9H4Z2 20 45948660-45972203 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063999, HPA071230" Enhanced Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA063999: AB_2685170, HPA071230: AB_2686369" "unprognostic (1.50e-1)" "unprognostic (8.05e-2)" "unprognostic (8.29e-3)" "unprognostic (7.85e-2)" "unprognostic (1.35e-2)" "prognostic favorable (4.48e-4)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.74e-2)" "unprognostic (1.01e-1)" "unprognostic (7.91e-2)" "unprognostic (1.30e-3)" "prognostic unfavorable (7.04e-4)" "prognostic unfavorable (2.77e-5)" "unprognostic (4.10e-1)" "unprognostic (1.94e-1)" "unprognostic (2.44e-1)" "unprognostic (2.88e-3)" 12.8 12.1 8.2 11.6 8.4 29.6 13.2 11.8 10.0 14.7 5.4 13.2 10.3 13.9 4.2 14.2 14.1 6.5 9.6 8.6 6.4 11.6 12.1 13.1 14.4 6.9 6.4 17.9 15.2 8.3 17.4 6.4 6.9 16.1 5.7 4.8 13.0 7.4 14.6 20.8 17.6 6.7 5.4 22.1 14.4 13.8 6.9 13.3 17.8 7.7 10.2 12.5 12.7 8.7 12.6 12.6 11.0 11.9 5.7 7.2 23.2 11.0 7.6 10.7 7.7 27.3 13.8 15.0 16.0 10.9 9.8 17.7 10.7 16.6 4.9 10.3 14.6 12.6 20.0 14.6 8.8 16.4 20.5 11.6 13.8 14.1 10.0 7.7 9.3 15.5 12.0 19.6 7.5 25.7 19.4 15.8 7.5 8.4 20.4 15.8 7.3 12.7 9.5 19.5 11.0 9.7 16.4 22.7 11.6 6.5 17.2 13.4 9.8 23.0 10.0 14.8 15.2 22.7 12.6 15.4 18.6 10.0 12.9 1.2 1.7 2.4 3.3 2.2 1.6 1.4 1.6 2.2 1.7 1.5 1.3 1.5 1.7 4.2 1.8 1.2 1.8 2.0 8.2 8.4 11.8 10.0 8.6 6.4 6.9 6.4 6.9 5.4 6.9 8.7 16.9 12.8 15.0 16.6 17.3 18.7 12.1 5.3 14.8 19.3 13.7 14.2 3.8 5.7 5.9 1.8 27.1 8.1 21.5 22.7 0.0 4.4 32.1 10.0 12.3 10.9 21.5 5.7 14.8 5.9 8.5 9.5 22.4 15.4 7.0 15.2 7.1 5.1 6.1 13.5 12.4 11.7 6.1 10.0 11.3 24.8 7.5 14.5 8.8 9.4 6.7 6.0 21.6 7.1 12.4 7.9 12.7 5.3 18.5 10.5 14.6 2.7 4.6 11.6 0.0 21.7 10.3 3.8 7.2 12.9 22.4 11.9 23.1 7.8 12.3 12.8 ZNF423 "Ebfaz, hOAZ, JBTS19, KIAA0760, NPHP14, OAZ, Zfp104" ENSG00000102935 "Zinc finger protein 423" Q2M1K9 16 49487524-49857919 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Disease variant, Joubert syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4;skeletal muscle: 27.5" "Cell type enhanced" "Detected in many" "Astrocytes: 75.4;Late spermatids: 115.7;Microglial cells: 53.4;Oligodendrocyte precursor cells: 38.7;Peritubular cells: 54.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 62.6;NTERA-2: 33.2;REH: 27.5;SCLC-21H: 35.1;SH-SY5Y: 87.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015258, HPA065820" Enhanced Nucleoplasm NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA015258: , HPA065820: AB_2685563" "unprognostic (2.81e-1)" "unprognostic (1.18e-1)" "unprognostic (1.19e-1)" "unprognostic (2.68e-1)" "unprognostic (2.86e-1)" "unprognostic (8.65e-3)" "unprognostic (3.37e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (2.77e-1)" "unprognostic (9.13e-2)" "unprognostic (8.97e-2)" "unprognostic (1.22e-1)" "unprognostic (6.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.92e-2)" "unprognostic (5.84e-2)" 9.1 2.9 13.5 2.3 9.6 0.3 6.7 14.0 10.2 6.3 1.0 4.3 1.3 5.4 3.4 4.7 9.3 5.8 7.8 9.7 11.0 2.0 0.7 2.9 1.9 14.9 30.4 7.6 3.4 3.0 4.0 4.2 11.8 6.0 2.7 3.6 2.8 9.5 27.5 2.0 2.6 6.5 8.6 1.4 2.0 4.5 26.3 1.8 4.3 14.7 1.2 3.9 5.4 7.8 0.0 0.0 62.6 3.3 5.1 0.6 7.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 1.4 0.0 0.0 1.9 0.5 0.0 3.6 0.1 0.2 0.0 0.0 4.4 0.3 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 8.8 0.4 33.2 0.0 0.0 27.5 0.1 0.0 0.0 1.7 35.1 87.7 0.0 0.1 0.0 17.6 0.0 0.0 0.0 0.0 1.0 16.4 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 13.5 9.6 14.0 10.2 9.7 11.0 14.9 30.4 11.8 8.6 26.3 7.8 12.7 0.0 0.0 75.4 0.0 2.7 0.3 0.1 1.2 9.8 0.6 0.6 2.6 0.0 0.0 0.0 0.0 0.5 0.1 2.3 1.9 0.2 23.5 2.7 7.6 11.4 0.0 0.0 10.9 0.2 0.7 15.8 0.0 0.6 0.0 1.6 15.4 0.9 0.7 0.0 7.4 1.0 0.0 0.3 5.1 115.7 27.7 0.4 1.8 53.4 0.0 11.7 0.0 38.7 5.1 0.2 0.4 54.5 0.2 0.1 0.2 0.6 0.0 1.1 0.0 4.5 6.4 0.8 1.9 0.1 1.7 0.3 0.3 5.5 0.7 0.1 ZNF462 "DKFZP762N2316, KIAA1803, Zfp462" ENSG00000148143 "Zinc finger protein 462" Q96JM2 9 106863166-107013634 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 114.9;Oligodendrocyte precursor cells: 486.5;Oligodendrocytes: 152.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022283 Uncertain Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA022283: AB_2220602" "unprognostic (4.22e-2)" "unprognostic (3.89e-2)" "unprognostic (2.60e-2)" "unprognostic (1.25e-2)" "unprognostic (1.99e-1)" "unprognostic (2.28e-1)" "unprognostic (2.04e-2)" "unprognostic (2.01e-1)" "unprognostic (3.62e-2)" "unprognostic (1.84e-2)" "unprognostic (2.16e-1)" "unprognostic (6.04e-2)" "prognostic favorable (6.19e-4)" "unprognostic (2.96e-2)" "unprognostic (1.68e-1)" "unprognostic (9.00e-2)" "unprognostic (1.33e-2)" 3.4 8.4 10.6 1.9 16.6 0.1 3.8 13.9 14.2 8.0 6.2 4.9 1.0 4.2 1.8 7.8 5.2 2.9 5.8 8.6 16.4 3.9 1.6 3.0 0.8 14.7 16.0 7.4 1.1 6.1 4.1 3.1 17.6 6.8 3.8 8.2 7.7 4.1 13.2 6.7 2.2 6.7 10.0 2.9 1.7 5.9 16.0 2.0 7.2 5.8 1.3 3.9 6.2 15.9 4.8 12.6 22.5 14.0 6.9 4.9 3.2 3.2 4.0 2.8 3.0 14.8 5.7 0.1 8.3 2.9 13.8 7.6 14.9 12.4 3.5 0.1 2.1 0.0 5.3 0.1 2.6 3.4 0.4 4.6 6.0 6.8 18.0 7.4 1.3 6.0 0.0 6.7 7.3 8.2 2.7 0.1 16.0 0.0 10.0 0.0 15.4 0.3 7.8 4.4 10.6 12.3 6.3 0.1 4.7 13.7 11.2 0.1 1.3 3.8 13.2 8.1 9.8 0.0 0.1 0.1 5.8 0.3 13.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 10.6 16.6 13.9 14.2 8.6 16.4 14.7 16.0 17.6 10.0 16.0 15.9 25.6 22.4 29.1 114.9 0.9 33.6 10.8 10.6 44.9 60.7 21.6 18.7 27.7 25.8 10.3 7.3 31.3 14.4 0.2 14.7 5.9 7.9 63.1 7.6 25.5 23.3 16.8 2.1 18.4 2.6 7.3 14.1 4.1 10.1 17.1 18.7 40.4 0.0 1.8 18.5 91.6 15.5 12.2 0.8 4.2 16.8 14.6 1.3 12.4 15.9 2.0 19.8 0.0 486.5 152.2 7.7 5.3 27.1 0.0 15.1 6.3 17.4 15.2 39.4 26.3 21.5 22.1 1.3 24.7 24.0 11.5 3.1 1.1 22.0 17.5 6.6 ZNF469 "KIAA1858, Zfp469" ENSG00000225614 "Zinc finger protein 469" Q96JG9 16 88382959-88440757 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 7.5;Excitatory neurons: 9.4;Granulosa cells: 9.3;Inhibitory neurons: 8.3;Oligodendrocyte precursor cells: 16.6;Sertoli cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.3;BJ hTERT+: 4.6;HeLa: 4.7;SiHa: 4.9;THP-1: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA077792 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Cell Junctions" "HPA077792: " "unprognostic (1.80e-1)" "unprognostic (7.79e-3)" "unprognostic (7.71e-2)" "unprognostic (7.01e-2)" "unprognostic (2.97e-1)" "unprognostic (2.30e-1)" "unprognostic (9.17e-3)" "unprognostic (7.08e-3)" "unprognostic (5.04e-2)" "unprognostic (5.02e-2)" "unprognostic (6.92e-2)" "unprognostic (1.01e-1)" "unprognostic (8.71e-7)" "unprognostic (2.24e-2)" "unprognostic (1.83e-2)" "unprognostic (2.20e-2)" "unprognostic (3.34e-2)" 0.9 0.5 3.2 0.9 1.1 0.1 0.5 0.3 2.0 1.4 0.0 0.3 0.2 1.6 0.0 0.1 0.7 0.9 0.4 3.4 0.4 0.1 0.1 0.3 0.6 2.2 1.6 2.2 0.4 0.1 0.1 0.3 1.3 0.8 0.0 0.0 0.4 0.3 0.7 0.3 0.4 0.8 1.0 0.8 0.4 0.2 1.3 0.4 0.1 0.1 0.2 0.9 0.4 1.2 0.0 4.3 0.1 0.0 0.6 0.9 0.0 2.6 4.6 0.6 0.0 0.0 0.1 0.0 0.1 3.6 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 4.7 0.0 2.9 0.1 0.1 1.0 0.0 1.0 0.0 0.7 2.7 0.0 0.0 0.0 0.7 0.4 0.0 0.6 0.5 0.0 3.4 0.3 0.0 0.0 0.0 0.0 0.0 2.1 4.9 0.0 0.0 0.0 0.9 6.4 3.3 3.6 0.9 2.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 1.1 0.3 2.0 3.4 0.4 2.2 1.6 1.3 1.0 1.3 1.2 0.3 0.0 1.8 2.0 0.8 0.3 0.6 1.1 0.0 0.5 2.1 1.1 7.5 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.2 0.6 1.1 2.3 0.0 0.0 9.4 0.0 0.1 3.9 0.0 0.1 0.0 9.3 2.9 0.0 3.1 3.3 8.3 0.0 0.0 1.4 0.6 0.2 0.0 1.9 0.0 1.9 1.6 0.6 2.1 16.6 0.8 0.7 0.0 1.5 0.2 1.1 0.0 0.2 1.1 0.1 6.6 1.3 4.8 0.1 0.7 0.0 0.1 0.1 0.5 1.7 0.0 0.3 ZSWIM6 KIAA1577 ENSG00000130449 "Zinc finger SWIM-type containing 6" Q9HCJ5 5 61332258-61546172 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 500.1;Microglial cells: 365.4;Oligodendrocyte precursor cells: 765.6;Oligodendrocytes: 740.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 44.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035938 Uncertain Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 70: Brain - Nervous system development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA035938: AB_10672077" "unprognostic (2.22e-1)" "unprognostic (2.08e-2)" "unprognostic (1.12e-1)" "unprognostic (2.10e-1)" "unprognostic (2.70e-1)" "unprognostic (6.69e-2)" "unprognostic (2.00e-1)" "unprognostic (6.96e-3)" "unprognostic (6.16e-2)" "unprognostic (1.40e-2)" "unprognostic (2.03e-1)" "unprognostic (1.94e-1)" "unprognostic (1.68e-2)" "unprognostic (7.50e-3)" "unprognostic (1.11e-1)" "unprognostic (3.63e-1)" "unprognostic (1.99e-1)" 8.1 5.4 11.0 8.9 17.0 3.8 5.8 13.0 14.3 6.6 4.1 9.6 6.0 5.0 5.5 8.8 6.3 9.5 4.8 11.0 12.0 5.1 7.8 13.4 5.7 15.7 13.6 7.2 7.7 5.8 6.4 7.8 14.9 8.3 10.7 8.3 6.9 6.4 3.4 5.3 7.5 6.2 12.4 7.0 10.0 7.4 14.2 6.9 6.5 2.5 5.0 7.6 8.4 26.5 6.0 7.8 35.4 2.5 7.5 13.6 3.0 7.9 7.1 8.6 13.2 3.1 9.4 1.5 6.7 9.9 13.7 5.1 7.9 9.6 12.0 25.0 7.4 2.9 16.3 1.7 9.9 1.9 4.1 9.9 7.0 20.2 17.2 11.8 21.3 3.3 0.9 29.3 35.4 4.3 1.6 3.8 5.4 1.8 5.8 11.8 10.3 44.4 14.1 7.7 7.2 11.3 18.7 1.1 7.3 13.7 3.1 7.7 29.8 7.1 9.2 9.9 11.4 5.1 0.8 3.2 11.0 2.3 15.4 0.9 1.1 0.5 0.0 0.9 0.3 0.2 0.1 0.1 0.5 0.3 0.1 0.1 1.6 0.4 1.3 1.3 0.1 0.2 11.0 17.0 13.0 14.3 11.0 12.0 15.7 13.6 14.9 12.4 14.2 26.5 24.5 25.6 12.6 500.1 13.3 47.4 80.2 12.0 42.1 6.9 25.8 20.4 12.2 25.8 27.1 11.0 10.4 0.4 29.5 38.4 1.9 12.0 12.7 47.4 37.4 23.6 14.2 1.7 223.4 12.9 0.5 22.7 28.1 86.1 14.5 9.6 27.8 8.0 25.9 8.4 167.7 25.8 14.2 59.3 49.0 8.5 5.6 53.3 16.0 365.4 34.0 15.6 2.1 765.6 740.4 19.2 30.2 6.4 14.3 40.6 9.4 4.9 28.8 5.1 6.6 19.5 22.7 18.9 18.8 32.2 39.9 1.4 15.7 27.1 19.8 58.3