[{"Gene":"ABCC8","Gene synonym":["ABC36","HHF1","HI","HRINS","MRP8","PHHI","SUR","SUR1","TNDM2"],"Ensembl":"ENSG00000006071","Gene description":"ATP binding cassette subfamily C member 8","Uniprot":["Q09428"],"Chromosome":"11","Position":"17392498-17476879","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":["Diabetes mellitus","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"pancreas":"20.1","pituitary gland":"34.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"19.6","Bipolar cells":"39.0","Endometrial stromal cells":"17.9","Enteroendocrine cells":"22.0","Excitatory neurons":"48.2","Inhibitory neurons":"39.3","Oligodendrocyte precursor cells":"39.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"pancreatic cancer":"16.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"A549":"1.8","AN3-CA":"1.4","SCLC-21H":"2.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011451","HPA042318"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"CAB011451":null,"HPA042318":"AB_2677947"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-5"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"2.8","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.8","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"3.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"2.6","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"20.1","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"34.4","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"3.3","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"1.5","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"6.1","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"3.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"1.4","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"3.3","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"3.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"39.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"2.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"ADAMTS9","Gene synonym":["KIAA1312"],"Ensembl":"ENSG00000163638","Gene description":"ADAM metallopeptidase with thrombospondin type 1 motif 9","Uniprot":["Q9P2N4"],"Chromosome":"3","Position":"64515654-64688000","Protein class":["Cancer-related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"41.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"166.3","Astrocytes":"84.2","Basal prostatic cells":"87.2","Endometrial stromal cells":"179.1","Endothelial cells":"221.0","Prostatic glandular cells":"115.7","Smooth muscle cells":"94.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HUVEC TERT2":"23.6","RPTEC TERT1":"27.1","SH-SY5Y":"128.3","SuSa":"40.5","WM-115":"28.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028567","HPA028577","HPA028601"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA028567":"AB_10599275","HPA028577":"AB_10600330","HPA028601":"AB_2672694"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-3"},"Tissue RNA - adipose tissue [nTPM]":"41.2","Tissue RNA - adrenal gland [nTPM]":"4.8","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"12.2","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"19.0","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"16.2","Tissue RNA - choroid plexus [nTPM]":"7.9","Tissue RNA - colon [nTPM]":"8.1","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"13.2","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"10.2","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"15.6","Tissue RNA - hippocampal formation [nTPM]":"4.4","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"9.5","Tissue RNA - liver [nTPM]":"2.7","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"10.8","Tissue RNA - midbrain [nTPM]":"8.1","Tissue RNA - ovary [nTPM]":"7.3","Tissue RNA - pancreas [nTPM]":"9.8","Tissue RNA - parathyroid gland [nTPM]":"6.3","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"31.7","Tissue RNA - pons [nTPM]":"8.5","Tissue RNA - prostate [nTPM]":"7.9","Tissue RNA - rectum [nTPM]":"2.7","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"3.7","Tissue RNA - skeletal muscle [nTPM]":"7.4","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"3.7","Tissue RNA - smooth muscle [nTPM]":"12.1","Tissue RNA - spinal cord [nTPM]":"8.0","Tissue RNA - spleen [nTPM]":"4.1","Tissue RNA - stomach 1 [nTPM]":"4.7","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"8.1","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"7.3","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"22.5","Tissue RNA - vagina [nTPM]":"9.0","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"13.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"1.3","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.5","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"8.8","Cell RNA - HSkMC [nTPM]":"2.6","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"23.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"7.5","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.4","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"27.1","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"128.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"40.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"5.4","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"28.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"4.4","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"10.8","Brain RNA - midbrain [nTPM]":"8.1","Brain RNA - pons [nTPM]":"8.5","Brain RNA - spinal cord [nTPM]":"8.0","Brain RNA - thalamus [nTPM]":"8.1","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"166.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"84.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"87.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"69.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"179.1","Single Cell Type RNA - Endothelial cells [nTPM]":"221.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"31.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"8.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"2.7","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"45.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"115.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"94.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"3.2","Single Cell Type RNA - Theca cells [nTPM]":"12.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"36.7"},{"Gene":"APPL1","Gene synonym":["APPL"],"Ensembl":"ENSG00000157500","Gene description":"Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1","Uniprot":["Q9UKG1"],"Chromosome":"3","Position":"57227726-57278105","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"28.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011138"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Actin filaments","Cytosol"],"Antibody RRID":{"HPA011138":"AB_1844959"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.26e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"11.6","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"14.8","Tissue RNA - basal ganglia [nTPM]":"9.7","Tissue RNA - bone marrow [nTPM]":"15.1","Tissue RNA - breast [nTPM]":"18.9","Tissue RNA - cerebellum [nTPM]":"12.9","Tissue RNA - cerebral cortex [nTPM]":"11.3","Tissue RNA - cervix [nTPM]":"17.1","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"14.2","Tissue RNA - duodenum [nTPM]":"12.6","Tissue RNA - endometrium 1 [nTPM]":"17.1","Tissue RNA - epididymis [nTPM]":"10.6","Tissue RNA - esophagus [nTPM]":"16.9","Tissue RNA - fallopian tube [nTPM]":"11.7","Tissue RNA - gallbladder [nTPM]":"13.0","Tissue RNA - heart muscle [nTPM]":"24.7","Tissue RNA - hippocampal formation [nTPM]":"9.7","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"16.5","Tissue RNA - liver [nTPM]":"12.9","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"16.7","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"10.1","Tissue RNA - ovary [nTPM]":"22.7","Tissue RNA - pancreas [nTPM]":"29.6","Tissue RNA - parathyroid gland [nTPM]":"25.1","Tissue RNA - pituitary gland [nTPM]":"7.8","Tissue RNA - placenta [nTPM]":"14.3","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"14.0","Tissue RNA - retina [nTPM]":"13.5","Tissue RNA - salivary gland [nTPM]":"15.2","Tissue RNA - seminal vesicle [nTPM]":"14.4","Tissue RNA - skeletal muscle [nTPM]":"44.2","Tissue RNA - skin 1 [nTPM]":"20.1","Tissue RNA - small intestine [nTPM]":"14.6","Tissue RNA - smooth muscle [nTPM]":"15.3","Tissue RNA - spinal cord [nTPM]":"10.4","Tissue RNA - spleen [nTPM]":"15.8","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"8.0","Tissue RNA - thalamus [nTPM]":"10.2","Tissue RNA - thymus [nTPM]":"18.9","Tissue RNA - thyroid gland [nTPM]":"19.8","Tissue RNA - tongue [nTPM]":"26.6","Tissue RNA - tonsil [nTPM]":"19.6","Tissue RNA - urinary bladder [nTPM]":"13.4","Tissue RNA - vagina [nTPM]":"11.9","Tissue RNA - white matter [nTPM]":"10.7","Cell RNA - A-431 [nTPM]":"30.2","Cell RNA - A549 [nTPM]":"12.9","Cell RNA - AF22 [nTPM]":"12.2","Cell RNA - AN3-CA [nTPM]":"45.4","Cell RNA - ASC diff [nTPM]":"21.2","Cell RNA - ASC TERT1 [nTPM]":"29.7","Cell RNA - BEWO [nTPM]":"26.2","Cell RNA - BJ [nTPM]":"15.5","Cell RNA - BJ hTERT+ [nTPM]":"9.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.8","Cell RNA - CACO-2 [nTPM]":"14.9","Cell RNA - CAPAN-2 [nTPM]":"17.5","Cell RNA - Daudi [nTPM]":"47.3","Cell RNA - EFO-21 [nTPM]":"6.2","Cell RNA - fHDF\/TERT166 [nTPM]":"24.6","Cell RNA - GAMG [nTPM]":"24.7","Cell RNA - HaCaT [nTPM]":"5.9","Cell RNA - HAP1 [nTPM]":"33.7","Cell RNA - HBEC3-KT [nTPM]":"27.3","Cell RNA - HBF TERT88 [nTPM]":"26.6","Cell RNA - HDLM-2 [nTPM]":"36.1","Cell RNA - HEK 293 [nTPM]":"15.0","Cell RNA - HEL [nTPM]":"27.6","Cell RNA - HeLa [nTPM]":"19.5","Cell RNA - Hep G2 [nTPM]":"16.1","Cell RNA - HHSteC [nTPM]":"22.7","Cell RNA - HL-60 [nTPM]":"59.6","Cell RNA - HMC-1 [nTPM]":"19.1","Cell RNA - HSkMC [nTPM]":"21.8","Cell RNA - hTCEpi [nTPM]":"24.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.3","Cell RNA - hTERT-HME1 [nTPM]":"21.3","Cell RNA - hTERT-RPE1 [nTPM]":"31.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.3","Cell RNA - JURKAT [nTPM]":"30.2","Cell RNA - K-562 [nTPM]":"9.0","Cell RNA - Karpas-707 [nTPM]":"30.0","Cell RNA - LHCN-M2 [nTPM]":"17.8","Cell RNA - MCF7 [nTPM]":"10.4","Cell RNA - MOLT-4 [nTPM]":"48.7","Cell RNA - NB-4 [nTPM]":"15.4","Cell RNA - NTERA-2 [nTPM]":"19.5","Cell RNA - OE19 [nTPM]":"21.6","Cell RNA - PC-3 [nTPM]":"21.7","Cell RNA - REH [nTPM]":"1.7","Cell RNA - RH-30 [nTPM]":"49.1","Cell RNA - RPMI-8226 [nTPM]":"26.1","Cell RNA - RPTEC TERT1 [nTPM]":"27.7","Cell RNA - RT4 [nTPM]":"16.7","Cell RNA - SCLC-21H [nTPM]":"12.5","Cell RNA - SH-SY5Y [nTPM]":"26.5","Cell RNA - SiHa [nTPM]":"21.1","Cell RNA - SK-BR-3 [nTPM]":"32.3","Cell RNA - SK-MEL-30 [nTPM]":"21.0","Cell RNA - SuSa [nTPM]":"16.7","Cell RNA - T-47d [nTPM]":"15.7","Cell RNA - THP-1 [nTPM]":"39.6","Cell RNA - TIME [nTPM]":"23.4","Cell RNA - U-138 MG [nTPM]":"25.1","Cell RNA - U-2 OS [nTPM]":"17.5","Cell RNA - U-2197 [nTPM]":"37.4","Cell RNA - U-251 MG [nTPM]":"29.9","Cell RNA - U-266\/70 [nTPM]":"27.0","Cell RNA - U-266\/84 [nTPM]":"41.8","Cell RNA - U-698 [nTPM]":"33.2","Cell RNA - U-87 MG [nTPM]":"27.4","Cell RNA - U-937 [nTPM]":"29.1","Cell RNA - WM-115 [nTPM]":"17.1","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"5.3","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"4.5","Blood RNA - MAIT T-cell [nTPM]":"4.9","Blood RNA - memory B-cell [nTPM]":"17.9","Blood RNA - memory CD4 T-cell [nTPM]":"3.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.3","Blood RNA - myeloid DC [nTPM]":"10.9","Blood RNA - naive B-cell [nTPM]":"28.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"7.4","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"18.0","Blood RNA - T-reg [nTPM]":"1.9","Blood RNA - total PBMC [nTPM]":"2.7","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"9.7","Brain RNA - cerebellum [nTPM]":"12.9","Brain RNA - cerebral cortex [nTPM]":"11.3","Brain RNA - hippocampal formation [nTPM]":"9.7","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"10.1","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"10.4","Brain RNA - thalamus [nTPM]":"10.2","Brain RNA - white matter [nTPM]":"10.7","Single Cell Type RNA - Adipocytes [nTPM]":"82.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.5","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"106.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"47.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"46.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"83.6","Single Cell Type RNA - Bipolar cells [nTPM]":"40.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"67.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"92.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"100.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"47.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.9","Single Cell Type RNA - dendritic cells [nTPM]":"70.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"29.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"58.7","Single Cell Type RNA - Ductal cells [nTPM]":"58.6","Single Cell Type RNA - Early spermatids [nTPM]":"42.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"35.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"92.8","Single Cell Type RNA - Endothelial cells [nTPM]":"66.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.6","Single Cell Type RNA - Erythroid cells [nTPM]":"20.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"60.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"44.7","Single Cell Type RNA - Fibroblasts [nTPM]":"68.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"59.4","Single Cell Type RNA - granulocytes [nTPM]":"23.4","Single Cell Type RNA - Granulosa cells [nTPM]":"60.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"40.0","Single Cell Type RNA - Hepatocytes [nTPM]":"44.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"52.2","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"50.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"36.2","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"68.6","Single Cell Type RNA - Langerhans cells [nTPM]":"50.6","Single Cell Type RNA - Late spermatids [nTPM]":"22.1","Single Cell Type RNA - Leydig cells [nTPM]":"73.0","Single Cell Type RNA - Macrophages [nTPM]":"71.0","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"87.8","Single Cell Type RNA - Muller glia cells [nTPM]":"56.6","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"43.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.7","Single Cell Type RNA - Paneth cells [nTPM]":"25.5","Single Cell Type RNA - Peritubular cells [nTPM]":"76.0","Single Cell Type RNA - Plasma cells [nTPM]":"62.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"58.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"55.4","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"94.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"61.2","Single Cell Type RNA - Spermatocytes [nTPM]":"64.9","Single Cell Type RNA - Spermatogonia [nTPM]":"44.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"105.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"69.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.0","Single Cell Type RNA - T-cells [nTPM]":"45.4","Single Cell Type RNA - Theca cells [nTPM]":"73.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"49.1","Single Cell Type RNA - Urothelial cells [nTPM]":"25.8"},{"Gene":"BACH2","Gene synonym":["BTBD25"],"Ensembl":"ENSG00000112182","Gene description":"BTB domain and CNC homolog 2","Uniprot":["Q9BYV9"],"Chromosome":"6","Position":"89926528-90296908","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"11.7","lymphoid tissue":"17.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"81.3","B-cells":"93.1","Excitatory neurons":"95.2","Horizontal cells":"198.5","Inhibitory neurons":"293.9","Oligodendrocyte precursor cells":"169.9","Oligodendrocytes":"253.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"14.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Daudi":"139.5","U-698":"78.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051384","HPA058384"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA051384":"AB_2681462","HPA058384":"AB_2683700"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-4"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"11.7","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"4.0","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"2.6","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"2.5","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"17.0","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"3.3","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"2.7","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"4.4","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"2.3","Tissue RNA - tonsil [nTPM]":"12.8","Tissue RNA - urinary bladder [nTPM]":"1.4","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"7.7","Cell RNA - A-431 [nTPM]":"1.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"5.1","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"139.5","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"1.7","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"3.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"8.6","Cell RNA - K-562 [nTPM]":"5.8","Cell RNA - Karpas-707 [nTPM]":"11.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"3.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"19.3","Cell RNA - RH-30 [nTPM]":"3.6","Cell RNA - RPMI-8226 [nTPM]":"2.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"12.8","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"8.9","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"78.8","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"1.4","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"14.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"4.0","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"7.7","Single Cell Type RNA - Adipocytes [nTPM]":"4.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"81.3","Single Cell Type RNA - B-cells [nTPM]":"93.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"5.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.2","Single Cell Type RNA - Early spermatids [nTPM]":"19.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"95.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"8.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"198.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"293.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"11.8","Single Cell Type RNA - Late spermatids [nTPM]":"10.6","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"3.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"2.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"169.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"253.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"7.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"23.6","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.5"},{"Gene":"BLK","Gene synonym":["MGC10442"],"Ensembl":"ENSG00000136573","Gene description":"BLK proto-oncogene, Src family tyrosine kinase","Uniprot":["P51451"],"Chromosome":"8","Position":"11486894-11564599","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"intestine":"39.1","lymphoid tissue":"46.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"B-cells":"116.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"183.4","naive B-cell":"131.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"183.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"106.6","REH":"29.9","RPMI-8226":"38.5","U-698":"48.6","U-87 MG":"22.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005093","HPA069571"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB005093":"AB_2274756","HPA069571":"AB_2732137"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"9.1","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.2","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"29.9","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"39.1","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"46.7","Tissue RNA - stomach 1 [nTPM]":"2.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"2.5","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"27.9","Tissue RNA - urinary bladder [nTPM]":"1.4","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"106.6","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"29.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"38.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"5.4","Cell RNA - U-266\/84 [nTPM]":"10.2","Cell RNA - U-698 [nTPM]":"48.6","Cell RNA - U-87 MG [nTPM]":"22.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"37.9","Blood RNA - memory B-cell [nTPM]":"183.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"131.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"17.5","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"9.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"116.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"4.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"10.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"4.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"C1QTNF6","Gene synonym":["CTRP6","ZACRP6"],"Ensembl":"ENSG00000133466","Gene description":"C1q and TNF related 6","Uniprot":["Q9BXI9"],"Chromosome":"22","Position":"37180166-37199385","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"31.7","placenta":"29.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"398.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"114.2","RT4":"50.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002042"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Secreted to blood","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":354000000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA002042":"AB_1078342"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.60e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.9","Tissue RNA - adrenal gland [nTPM]":"6.7","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"4.5","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"4.0","Tissue RNA - cerebellum [nTPM]":"4.3","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"11.1","Tissue RNA - choroid plexus [nTPM]":"4.3","Tissue RNA - colon [nTPM]":"5.5","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"31.7","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"2.7","Tissue RNA - fallopian tube [nTPM]":"7.0","Tissue RNA - gallbladder [nTPM]":"8.8","Tissue RNA - heart muscle [nTPM]":"3.7","Tissue RNA - hippocampal formation [nTPM]":"4.5","Tissue RNA - hypothalamus [nTPM]":"4.3","Tissue RNA - kidney [nTPM]":"7.4","Tissue RNA - liver [nTPM]":"13.0","Tissue RNA - lung [nTPM]":"5.2","Tissue RNA - lymph node [nTPM]":"5.1","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"5.5","Tissue RNA - pancreas [nTPM]":"3.5","Tissue RNA - parathyroid gland [nTPM]":"2.2","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"29.6","Tissue RNA - pons [nTPM]":"4.8","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"5.4","Tissue RNA - smooth muscle [nTPM]":"8.2","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"3.5","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"4.8","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"3.8","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"4.3","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"17.7","Cell RNA - A549 [nTPM]":"20.5","Cell RNA - AF22 [nTPM]":"10.7","Cell RNA - AN3-CA [nTPM]":"3.6","Cell RNA - ASC diff [nTPM]":"1.8","Cell RNA - ASC TERT1 [nTPM]":"21.3","Cell RNA - BEWO [nTPM]":"32.6","Cell RNA - BJ [nTPM]":"3.4","Cell RNA - BJ hTERT+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"3.8","Cell RNA - CAPAN-2 [nTPM]":"24.7","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"14.1","Cell RNA - fHDF\/TERT166 [nTPM]":"6.0","Cell RNA - GAMG [nTPM]":"1.5","Cell RNA - HaCaT [nTPM]":"34.9","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"8.4","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"4.9","Cell RNA - HEK 293 [nTPM]":"2.6","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"8.3","Cell RNA - Hep G2 [nTPM]":"3.8","Cell RNA - HHSteC [nTPM]":"7.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"2.3","Cell RNA - HSkMC [nTPM]":"29.2","Cell RNA - hTCEpi [nTPM]":"4.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.3","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"7.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.5","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"7.7","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"114.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"7.1","Cell RNA - OE19 [nTPM]":"2.5","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"2.8","Cell RNA - RPTEC TERT1 [nTPM]":"24.5","Cell RNA - RT4 [nTPM]":"50.7","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"14.6","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"19.7","Cell RNA - SK-MEL-30 [nTPM]":"2.8","Cell RNA - SuSa [nTPM]":"5.5","Cell RNA - T-47d [nTPM]":"7.0","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"9.4","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"5.6","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"15.5","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"2.1","Cell RNA - U-937 [nTPM]":"2.0","Cell RNA - WM-115 [nTPM]":"3.2","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"4.5","Brain RNA - cerebellum [nTPM]":"4.3","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"4.5","Brain RNA - hypothalamus [nTPM]":"4.3","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"4.8","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"4.8","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"2.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.8","Single Cell Type RNA - Endothelial cells [nTPM]":"6.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"398.9","Single Cell Type RNA - Fibroblasts [nTPM]":"7.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"19.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"7.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"8.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"4.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.7","Single Cell Type RNA - Paneth cells [nTPM]":"2.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"3.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.5","Single Cell Type RNA - Spermatocytes [nTPM]":"7.2","Single Cell Type RNA - Spermatogonia [nTPM]":"4.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.5","Single Cell Type RNA - T-cells [nTPM]":"3.1","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"CAPN10","Gene synonym":[],"Ensembl":"ENSG00000142330","Gene description":"Calpain 10","Uniprot":["Q9HC96"],"Chromosome":"2","Position":"240586734-240617705","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"48.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004170","HPA056098"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA004170":"AB_1078381","HPA056098":"AB_2683037"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.47e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.78e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.94e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.0","Tissue RNA - adrenal gland [nTPM]":"18.6","Tissue RNA - amygdala [nTPM]":"16.8","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"16.2","Tissue RNA - bone marrow [nTPM]":"7.9","Tissue RNA - breast [nTPM]":"9.6","Tissue RNA - cerebellum [nTPM]":"21.0","Tissue RNA - cerebral cortex [nTPM]":"25.0","Tissue RNA - cervix [nTPM]":"11.8","Tissue RNA - choroid plexus [nTPM]":"16.5","Tissue RNA - colon [nTPM]":"12.7","Tissue RNA - duodenum [nTPM]":"13.1","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"14.5","Tissue RNA - fallopian tube [nTPM]":"13.7","Tissue RNA - gallbladder [nTPM]":"6.1","Tissue RNA - heart muscle [nTPM]":"24.6","Tissue RNA - hippocampal formation [nTPM]":"17.9","Tissue RNA - hypothalamus [nTPM]":"14.0","Tissue RNA - kidney [nTPM]":"23.8","Tissue RNA - liver [nTPM]":"14.7","Tissue RNA - lung [nTPM]":"12.2","Tissue RNA - lymph node [nTPM]":"10.6","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"15.8","Tissue RNA - ovary [nTPM]":"13.3","Tissue RNA - pancreas [nTPM]":"12.6","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"18.1","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"15.4","Tissue RNA - prostate [nTPM]":"14.9","Tissue RNA - rectum [nTPM]":"7.1","Tissue RNA - retina [nTPM]":"10.6","Tissue RNA - salivary gland [nTPM]":"10.2","Tissue RNA - seminal vesicle [nTPM]":"5.3","Tissue RNA - skeletal muscle [nTPM]":"5.8","Tissue RNA - skin 1 [nTPM]":"12.1","Tissue RNA - small intestine [nTPM]":"14.0","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"12.6","Tissue RNA - spleen [nTPM]":"29.8","Tissue RNA - stomach 1 [nTPM]":"15.8","Tissue RNA - testis [nTPM]":"17.0","Tissue RNA - thalamus [nTPM]":"16.7","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"5.4","Tissue RNA - urinary bladder [nTPM]":"11.1","Tissue RNA - vagina [nTPM]":"10.0","Tissue RNA - white matter [nTPM]":"16.8","Cell RNA - A-431 [nTPM]":"8.0","Cell RNA - A549 [nTPM]":"11.2","Cell RNA - AF22 [nTPM]":"11.2","Cell RNA - AN3-CA [nTPM]":"9.5","Cell RNA - ASC diff [nTPM]":"4.5","Cell RNA - ASC TERT1 [nTPM]":"3.6","Cell RNA - BEWO [nTPM]":"19.7","Cell RNA - BJ [nTPM]":"9.9","Cell RNA - BJ hTERT+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.9","Cell RNA - CACO-2 [nTPM]":"8.7","Cell RNA - CAPAN-2 [nTPM]":"18.7","Cell RNA - Daudi [nTPM]":"5.9","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.6","Cell RNA - GAMG [nTPM]":"8.9","Cell RNA - HaCaT [nTPM]":"12.7","Cell RNA - HAP1 [nTPM]":"3.0","Cell RNA - HBEC3-KT [nTPM]":"6.6","Cell RNA - HBF TERT88 [nTPM]":"3.3","Cell RNA - HDLM-2 [nTPM]":"23.0","Cell RNA - HEK 293 [nTPM]":"19.8","Cell RNA - HEL [nTPM]":"10.9","Cell RNA - HeLa [nTPM]":"20.4","Cell RNA - Hep G2 [nTPM]":"16.0","Cell RNA - HHSteC [nTPM]":"7.1","Cell RNA - HL-60 [nTPM]":"7.1","Cell RNA - HMC-1 [nTPM]":"15.3","Cell RNA - HSkMC [nTPM]":"2.6","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.7","Cell RNA - hTERT-HME1 [nTPM]":"2.7","Cell RNA - hTERT-RPE1 [nTPM]":"6.7","Cell RNA - HUVEC TERT2 [nTPM]":"5.2","Cell RNA - JURKAT [nTPM]":"16.8","Cell RNA - K-562 [nTPM]":"12.5","Cell RNA - Karpas-707 [nTPM]":"7.3","Cell RNA - LHCN-M2 [nTPM]":"2.8","Cell RNA - MCF7 [nTPM]":"7.1","Cell RNA - MOLT-4 [nTPM]":"16.2","Cell RNA - NB-4 [nTPM]":"27.5","Cell RNA - NTERA-2 [nTPM]":"17.4","Cell RNA - OE19 [nTPM]":"9.5","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"15.5","Cell RNA - RH-30 [nTPM]":"8.1","Cell RNA - RPMI-8226 [nTPM]":"13.1","Cell RNA - RPTEC TERT1 [nTPM]":"9.9","Cell RNA - RT4 [nTPM]":"9.8","Cell RNA - SCLC-21H [nTPM]":"28.1","Cell RNA - SH-SY5Y [nTPM]":"22.0","Cell RNA - SiHa [nTPM]":"6.3","Cell RNA - SK-BR-3 [nTPM]":"9.3","Cell RNA - SK-MEL-30 [nTPM]":"13.8","Cell RNA - SuSa [nTPM]":"3.5","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"9.3","Cell RNA - TIME [nTPM]":"8.6","Cell RNA - U-138 MG [nTPM]":"11.0","Cell RNA - U-2 OS [nTPM]":"9.7","Cell RNA - U-2197 [nTPM]":"9.5","Cell RNA - U-251 MG [nTPM]":"11.8","Cell RNA - U-266\/70 [nTPM]":"16.3","Cell RNA - U-266\/84 [nTPM]":"4.2","Cell RNA - U-698 [nTPM]":"10.7","Cell RNA - U-87 MG [nTPM]":"10.4","Cell RNA - U-937 [nTPM]":"12.8","Cell RNA - WM-115 [nTPM]":"11.0","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"4.1","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"16.8","Brain RNA - basal ganglia [nTPM]":"16.2","Brain RNA - cerebellum [nTPM]":"21.0","Brain RNA - cerebral cortex [nTPM]":"25.0","Brain RNA - hippocampal formation [nTPM]":"17.9","Brain RNA - hypothalamus [nTPM]":"14.0","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"15.8","Brain RNA - pons [nTPM]":"15.4","Brain RNA - spinal cord [nTPM]":"12.6","Brain RNA - thalamus [nTPM]":"16.7","Brain RNA - white matter [nTPM]":"16.8","Single Cell Type RNA - Adipocytes [nTPM]":"8.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"7.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"4.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.4","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.3","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.2","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.8","Single Cell Type RNA - granulocytes [nTPM]":"22.9","Single Cell Type RNA - Granulosa cells [nTPM]":"11.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"3.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.7","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"7.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"7.7","Single Cell Type RNA - Muller glia cells [nTPM]":"13.4","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.8","Single Cell Type RNA - Paneth cells [nTPM]":"4.6","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"7.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.6","Single Cell Type RNA - Spermatocytes [nTPM]":"12.6","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - T-cells [nTPM]":"11.3","Single Cell Type RNA - Theca cells [nTPM]":"9.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.9"},{"Gene":"CD226","Gene synonym":["DNAM-1","DNAM1","PTA1","TLiSA1"],"Ensembl":"ENSG00000150637","Gene description":"CD226 molecule","Uniprot":["Q15762"],"Chromosome":"18","Position":"69831158-69961803","Protein class":["CD markers","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"20.2","parathyroid gland":"62.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"52.1","Macrophages":"24.4","Microglial cells":"22.5","NK-cells":"90.6","Oligodendrocytes":"26.6","T-cells":"43.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"gdT-cell":"36.6","MAIT T-cell":"13.4","memory CD4 T-cell":"28.8","memory CD8 T-cell":"22.5","naive CD4 T-cell":"15.8","naive CD8 T-cell":"17.3","NK-cell":"29.7","T-reg":"11.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"NK-cells":"29.7","T-cells":"36.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"HEL":"100.0","HMC-1":"42.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015715","HPA015865"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Centriolar satellite"],"Antibody RRID":{"HPA015715":"AB_1846278","HPA015865":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"6.4","Tissue RNA - bone marrow [nTPM]":"4.4","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.8","Tissue RNA - duodenum [nTPM]":"2.3","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"1.5","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"4.2","Tissue RNA - lymph node [nTPM]":"9.7","Tissue RNA - medulla oblongata [nTPM]":"3.1","Tissue RNA - midbrain [nTPM]":"3.3","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"62.4","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"1.5","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"3.1","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"20.2","Tissue RNA - stomach 1 [nTPM]":"3.2","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"3.1","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"5.3","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"100.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"42.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.9","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"9.3","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"11.5","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"36.6","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"13.4","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"28.8","Blood RNA - memory CD8 T-cell [nTPM]":"22.5","Blood RNA - myeloid DC [nTPM]":"2.9","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"15.8","Blood RNA - naive CD8 T-cell [nTPM]":"17.3","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"29.7","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"11.3","Blood RNA - total PBMC [nTPM]":"13.2","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"6.4","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"3.1","Brain RNA - midbrain [nTPM]":"3.3","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.6","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"3.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"52.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"13.9","Single Cell Type RNA - Granulosa cells [nTPM]":"1.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.7","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"8.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"24.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"14.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"90.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"13.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"43.2","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"CDKAL1","Gene synonym":["FLJ20342"],"Ensembl":"ENSG00000145996","Gene description":"CDK5 regulatory subunit associated protein 1 like 1","Uniprot":["Q5VV42"],"Chromosome":"6","Position":"20534457-21232404","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["tRNA processing"],"Molecular function":["Transferase"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"133.2","Excitatory neurons":"159.5","Inhibitory neurons":"134.1","Microglial cells":"198.6","Oligodendrocyte precursor cells":"198.5","Oligodendrocytes":"255.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SCLC-21H":"188.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.6","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"5.8","Tissue RNA - basal ganglia [nTPM]":"5.7","Tissue RNA - bone marrow [nTPM]":"9.5","Tissue RNA - breast [nTPM]":"6.9","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"6.6","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"5.2","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"5.8","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"6.8","Tissue RNA - gallbladder [nTPM]":"6.3","Tissue RNA - heart muscle [nTPM]":"4.7","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"8.2","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"8.5","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"6.5","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"5.9","Tissue RNA - seminal vesicle [nTPM]":"4.9","Tissue RNA - skeletal muscle [nTPM]":"14.0","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"6.4","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"6.7","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"9.6","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"9.5","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"5.7","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"5.3","Cell RNA - AF22 [nTPM]":"12.1","Cell RNA - AN3-CA [nTPM]":"15.6","Cell RNA - ASC diff [nTPM]":"6.7","Cell RNA - ASC TERT1 [nTPM]":"9.0","Cell RNA - BEWO [nTPM]":"12.8","Cell RNA - BJ [nTPM]":"9.0","Cell RNA - BJ hTERT+ [nTPM]":"8.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.1","Cell RNA - CACO-2 [nTPM]":"9.8","Cell RNA - CAPAN-2 [nTPM]":"7.7","Cell RNA - Daudi [nTPM]":"20.7","Cell RNA - EFO-21 [nTPM]":"22.0","Cell RNA - fHDF\/TERT166 [nTPM]":"7.7","Cell RNA - GAMG [nTPM]":"14.1","Cell RNA - HaCaT [nTPM]":"8.6","Cell RNA - HAP1 [nTPM]":"16.5","Cell RNA - HBEC3-KT [nTPM]":"9.1","Cell RNA - HBF TERT88 [nTPM]":"17.3","Cell RNA - HDLM-2 [nTPM]":"37.3","Cell RNA - HEK 293 [nTPM]":"9.1","Cell RNA - HEL [nTPM]":"17.7","Cell RNA - HeLa [nTPM]":"9.1","Cell RNA - Hep G2 [nTPM]":"13.3","Cell RNA - HHSteC [nTPM]":"8.7","Cell RNA - HL-60 [nTPM]":"17.6","Cell RNA - HMC-1 [nTPM]":"11.7","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"9.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.5","Cell RNA - hTERT-HME1 [nTPM]":"11.5","Cell RNA - hTERT-RPE1 [nTPM]":"8.0","Cell RNA - HUVEC TERT2 [nTPM]":"12.0","Cell RNA - JURKAT [nTPM]":"12.6","Cell RNA - K-562 [nTPM]":"23.3","Cell RNA - Karpas-707 [nTPM]":"8.2","Cell RNA - LHCN-M2 [nTPM]":"9.7","Cell RNA - MCF7 [nTPM]":"7.3","Cell RNA - MOLT-4 [nTPM]":"22.4","Cell RNA - NB-4 [nTPM]":"21.0","Cell RNA - NTERA-2 [nTPM]":"8.5","Cell RNA - OE19 [nTPM]":"8.9","Cell RNA - PC-3 [nTPM]":"5.8","Cell RNA - REH [nTPM]":"13.1","Cell RNA - RH-30 [nTPM]":"16.1","Cell RNA - RPMI-8226 [nTPM]":"19.5","Cell RNA - RPTEC TERT1 [nTPM]":"16.6","Cell RNA - RT4 [nTPM]":"9.9","Cell RNA - SCLC-21H [nTPM]":"188.5","Cell RNA - SH-SY5Y [nTPM]":"11.1","Cell RNA - SiHa [nTPM]":"10.0","Cell RNA - SK-BR-3 [nTPM]":"16.0","Cell RNA - SK-MEL-30 [nTPM]":"13.2","Cell RNA - SuSa [nTPM]":"10.2","Cell RNA - T-47d [nTPM]":"11.7","Cell RNA - THP-1 [nTPM]":"8.8","Cell RNA - TIME [nTPM]":"11.7","Cell RNA - U-138 MG [nTPM]":"15.2","Cell RNA - U-2 OS [nTPM]":"10.4","Cell RNA - U-2197 [nTPM]":"6.1","Cell RNA - U-251 MG [nTPM]":"16.8","Cell RNA - U-266\/70 [nTPM]":"12.9","Cell RNA - U-266\/84 [nTPM]":"36.8","Cell RNA - U-698 [nTPM]":"17.7","Cell RNA - U-87 MG [nTPM]":"5.5","Cell RNA - U-937 [nTPM]":"9.9","Cell RNA - WM-115 [nTPM]":"26.0","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"3.1","Blood RNA - gdT-cell [nTPM]":"6.4","Blood RNA - intermediate monocyte [nTPM]":"5.3","Blood RNA - MAIT T-cell [nTPM]":"5.3","Blood RNA - memory B-cell [nTPM]":"7.0","Blood RNA - memory CD4 T-cell [nTPM]":"6.3","Blood RNA - memory CD8 T-cell [nTPM]":"6.5","Blood RNA - myeloid DC [nTPM]":"4.4","Blood RNA - naive B-cell [nTPM]":"6.4","Blood RNA - naive CD4 T-cell [nTPM]":"7.7","Blood RNA - naive CD8 T-cell [nTPM]":"7.1","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"10.3","Blood RNA - non-classical monocyte [nTPM]":"11.2","Blood RNA - plasmacytoid DC [nTPM]":"4.6","Blood RNA - T-reg [nTPM]":"7.4","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"5.7","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"13.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"133.2","Single Cell Type RNA - B-cells [nTPM]":"19.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"8.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - dendritic cells [nTPM]":"12.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"8.3","Single Cell Type RNA - Early spermatids [nTPM]":"15.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.6","Single Cell Type RNA - Endothelial cells [nTPM]":"12.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.4","Single Cell Type RNA - Erythroid cells [nTPM]":"6.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"159.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.5","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"12.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"6.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"134.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.1","Single Cell Type RNA - Langerhans cells [nTPM]":"7.6","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"9.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"198.6","Single Cell Type RNA - monocytes [nTPM]":"13.2","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"198.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"255.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.8","Single Cell Type RNA - Paneth cells [nTPM]":"5.8","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"20.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.7","Single Cell Type RNA - Spermatocytes [nTPM]":"13.3","Single Cell Type RNA - Spermatogonia [nTPM]":"11.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"17.4","Single Cell Type RNA - Theca cells [nTPM]":"5.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.3"},{"Gene":"CDKN2A","Gene synonym":["ARF","CDK4I","CDKN2","CMM2","INK4","INK4a","MLM","MTS1","p14","p14ARF","p16","p16INK4a","p19","p19Arf"],"Ensembl":"ENSG00000147889","Gene description":"Cyclin dependent kinase inhibitor 2A","Uniprot":["P42771","Q8N726"],"Chromosome":"9","Position":"21967752-21995301","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle","rRNA processing","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"31.7","pituitary gland":"33.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"170.1","Club cells":"145.9","Early spermatids":"227.5","Late spermatids":"447.9","Pancreatic endocrine cells":"417.7","Respiratory ciliated cells":"221.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"49.9","ovarian cancer":"57.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"37.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"15.6","T-cells":"37.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"289.2","HEK 293":"389.7","HeLa":"311.1","SK-MEL-30":"318.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000093","CAB000445","CAB018232","HPA047838"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"CAB000093":"AB_442119","CAB000445":null,"CAB018232":"AB_785018","HPA047838":"AB_2680174"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.82e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.19e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.76e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"10.1","Tissue RNA - amygdala [nTPM]":"7.4","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"31.7","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"6.4","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"2.3","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"7.4","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"33.7","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"7.2","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"5.5","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"14.8","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"2.4","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"9.2","Cell RNA - A-431 [nTPM]":"11.8","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.7","Cell RNA - AN3-CA [nTPM]":"82.2","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"39.1","Cell RNA - BJ [nTPM]":"15.9","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"111.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"196.0","Cell RNA - CACO-2 [nTPM]":"19.1","Cell RNA - CAPAN-2 [nTPM]":"289.2","Cell RNA - Daudi [nTPM]":"47.1","Cell RNA - EFO-21 [nTPM]":"167.7","Cell RNA - fHDF\/TERT166 [nTPM]":"9.5","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"36.0","Cell RNA - HAP1 [nTPM]":"34.3","Cell RNA - HBEC3-KT [nTPM]":"211.0","Cell RNA - HBF TERT88 [nTPM]":"91.4","Cell RNA - HDLM-2 [nTPM]":"212.2","Cell RNA - HEK 293 [nTPM]":"389.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"311.1","Cell RNA - Hep G2 [nTPM]":"13.6","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"22.4","Cell RNA - HMC-1 [nTPM]":"17.3","Cell RNA - HSkMC [nTPM]":"21.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.2","Cell RNA - hTERT-HME1 [nTPM]":"61.9","Cell RNA - hTERT-RPE1 [nTPM]":"236.3","Cell RNA - HUVEC TERT2 [nTPM]":"11.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"188.4","Cell RNA - LHCN-M2 [nTPM]":"105.7","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"24.2","Cell RNA - PC-3 [nTPM]":"185.9","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"80.2","Cell RNA - RPMI-8226 [nTPM]":"166.3","Cell RNA - RPTEC TERT1 [nTPM]":"23.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"195.2","Cell RNA - SH-SY5Y [nTPM]":"14.0","Cell RNA - SiHa [nTPM]":"219.9","Cell RNA - SK-BR-3 [nTPM]":"36.6","Cell RNA - SK-MEL-30 [nTPM]":"318.7","Cell RNA - SuSa [nTPM]":"9.4","Cell RNA - T-47d [nTPM]":"42.8","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"39.5","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"2.6","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"84.7","Cell RNA - U-266\/84 [nTPM]":"49.6","Cell RNA - U-698 [nTPM]":"177.8","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"62.9","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"14.1","Blood RNA - memory B-cell [nTPM]":"11.1","Blood RNA - memory CD4 T-cell [nTPM]":"11.4","Blood RNA - memory CD8 T-cell [nTPM]":"17.6","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"15.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"4.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"37.4","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"7.4","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"6.4","Brain RNA - medulla oblongata [nTPM]":"7.4","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"7.2","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"9.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"11.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"170.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"145.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"29.7","Single Cell Type RNA - Early spermatids [nTPM]":"227.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"70.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.8","Single Cell Type RNA - Fibroblasts [nTPM]":"7.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.3","Single Cell Type RNA - Ionocytes [nTPM]":"122.1","Single Cell Type RNA - Kupffer cells [nTPM]":"10.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"447.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"16.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"417.7","Single Cell Type RNA - Paneth cells [nTPM]":"12.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"38.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"221.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.8","Single Cell Type RNA - Spermatocytes [nTPM]":"7.2","Single Cell Type RNA - Spermatogonia [nTPM]":"6.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - T-cells [nTPM]":"12.7","Single Cell Type RNA - Theca cells [nTPM]":"11.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.8","Single Cell Type RNA - Urothelial cells [nTPM]":"54.4"},{"Gene":"CDKN2B","Gene synonym":["CDK4I","INK4B","MTS2","P15","p15INK4b","TP15"],"Ensembl":"ENSG00000147883","Gene description":"Cyclin dependent kinase inhibitor 2B","Uniprot":["P42772"],"Chromosome":"9","Position":"22002903-22009305","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"36.2","intestine":"30.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"240.7","Pancreatic endocrine cells":"164.5","Proximal enterocytes":"139.0","Squamous epithelial cells":"142.0","Urothelial cells":"241.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"classical monocyte":"3.3","intermediate monocyte":"3.3","non-classical monocyte":"9.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"monocytes":"9.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"38.1","HaCaT":"35.0","HeLa":"33.9","hTERT-RPE1":"60.1","SiHa":"48.0","SK-MEL-30":"35.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000349","HPA052838","HPA063327"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000349":null,"HPA052838":null,"HPA063327":"AB_2684987"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.47e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.7","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"8.6","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"22.4","Tissue RNA - duodenum [nTPM]":"21.7","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"36.2","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"1.2","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"12.6","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"2.3","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"3.6","Tissue RNA - rectum [nTPM]":"19.7","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"7.2","Tissue RNA - skin 1 [nTPM]":"12.9","Tissue RNA - small intestine [nTPM]":"30.9","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"6.0","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"8.1","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"20.2","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"2.1","Cell RNA - ASC diff [nTPM]":"28.2","Cell RNA - ASC TERT1 [nTPM]":"38.1","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"1.8","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.6","Cell RNA - CACO-2 [nTPM]":"3.6","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.4","Cell RNA - fHDF\/TERT166 [nTPM]":"2.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"35.0","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"6.9","Cell RNA - HBF TERT88 [nTPM]":"5.5","Cell RNA - HDLM-2 [nTPM]":"2.6","Cell RNA - HEK 293 [nTPM]":"9.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"33.9","Cell RNA - Hep G2 [nTPM]":"1.5","Cell RNA - HHSteC [nTPM]":"14.4","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"6.1","Cell RNA - HSkMC [nTPM]":"8.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.5","Cell RNA - hTERT-HME1 [nTPM]":"25.8","Cell RNA - hTERT-RPE1 [nTPM]":"60.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"17.1","Cell RNA - LHCN-M2 [nTPM]":"7.3","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"1.7","Cell RNA - PC-3 [nTPM]":"19.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.4","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"10.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"48.0","Cell RNA - SK-BR-3 [nTPM]":"11.5","Cell RNA - SK-MEL-30 [nTPM]":"35.7","Cell RNA - SuSa [nTPM]":"25.8","Cell RNA - T-47d [nTPM]":"3.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"14.8","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"13.5","Cell RNA - U-266\/84 [nTPM]":"8.4","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"9.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"2.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"40.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"37.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"3.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"240.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"57.7","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.5","Single Cell Type RNA - Endothelial cells [nTPM]":"4.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"11.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.6","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"3.2","Single Cell Type RNA - Muller glia cells [nTPM]":"4.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"164.5","Single Cell Type RNA - Paneth cells [nTPM]":"75.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"65.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"139.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.9","Single Cell Type RNA - Spermatocytes [nTPM]":"13.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"142.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.3","Single Cell Type RNA - Urothelial cells [nTPM]":"241.6"},{"Gene":"CEL","Gene synonym":["BSSL","MODY8"],"Ensembl":"ENSG00000170835","Gene description":"Carboxyl ester lipase","Uniprot":["P19835"],"Chromosome":"9","Position":"133061981-133071861","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase","Serine esterase"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"548","RNA tissue specific nTPM":{"pancreas":"110578.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Breast glandular cells":"390.7","Exocrine glandular cells":"943.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"29","RNA cancer specific FPKM":{"pancreatic cancer":"469.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"JURKAT":"7.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008023","HPA052701"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008023":"AB_1846509","HPA052701":"AB_2681921"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.14e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.0","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"10.4","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"6.4","Tissue RNA - choroid plexus [nTPM]":"13.5","Tissue RNA - colon [nTPM]":"2.9","Tissue RNA - duodenum [nTPM]":"21.6","Tissue RNA - endometrium 1 [nTPM]":"3.2","Tissue RNA - epididymis [nTPM]":"200.8","Tissue RNA - esophagus [nTPM]":"7.1","Tissue RNA - fallopian tube [nTPM]":"11.1","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"22.0","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"6.4","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"57.2","Tissue RNA - pancreas [nTPM]":"110578.0","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"201.7","Tissue RNA - placenta [nTPM]":"7.1","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"19.9","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"9.2","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"3.4","Tissue RNA - stomach 1 [nTPM]":"18.5","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"1.9","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"3.4","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"3.1","Cell RNA - AN3-CA [nTPM]":"1.9","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"5.9","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"1.9","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"5.9","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"3.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"7.5","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"1.8","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"2.7","Cell RNA - SCLC-21H [nTPM]":"5.3","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"4.5","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"2.9","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"2.0","Cell RNA - U-2197 [nTPM]":"1.7","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"3.4","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.6","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"390.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"943.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"6.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"6.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.0"},{"Gene":"CISD2","Gene synonym":["ERIS","Miner1","NAF-1","WFS2","ZCD2"],"Ensembl":"ENSG00000145354","Gene description":"CDGSH iron sulfur domain 2","Uniprot":["Q8N5K1"],"Chromosome":"4","Position":"102868974-102892807","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Deafness","Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"46.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"256.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015914"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA015914":"AB_1846794"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.2","Tissue RNA - adrenal gland [nTPM]":"19.1","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"2.7","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"9.0","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"3.2","Tissue RNA - cervix [nTPM]":"9.5","Tissue RNA - choroid plexus [nTPM]":"4.1","Tissue RNA - colon [nTPM]":"11.5","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"9.5","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"12.5","Tissue RNA - fallopian tube [nTPM]":"8.8","Tissue RNA - gallbladder [nTPM]":"4.3","Tissue RNA - heart muscle [nTPM]":"10.5","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"3.2","Tissue RNA - kidney [nTPM]":"17.9","Tissue RNA - liver [nTPM]":"46.0","Tissue RNA - lung [nTPM]":"10.7","Tissue RNA - lymph node [nTPM]":"5.5","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"20.0","Tissue RNA - parathyroid gland [nTPM]":"5.4","Tissue RNA - pituitary gland [nTPM]":"12.8","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"9.5","Tissue RNA - rectum [nTPM]":"3.8","Tissue RNA - retina [nTPM]":"6.1","Tissue RNA - salivary gland [nTPM]":"12.0","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"7.4","Tissue RNA - skin 1 [nTPM]":"9.7","Tissue RNA - small intestine [nTPM]":"10.9","Tissue RNA - smooth muscle [nTPM]":"3.0","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"14.7","Tissue RNA - stomach 1 [nTPM]":"11.4","Tissue RNA - testis [nTPM]":"6.5","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"13.6","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"3.5","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"10.1","Tissue RNA - white matter [nTPM]":"4.0","Cell RNA - A-431 [nTPM]":"16.8","Cell RNA - A549 [nTPM]":"5.5","Cell RNA - AF22 [nTPM]":"5.8","Cell RNA - AN3-CA [nTPM]":"7.2","Cell RNA - ASC diff [nTPM]":"14.2","Cell RNA - ASC TERT1 [nTPM]":"15.2","Cell RNA - BEWO [nTPM]":"3.7","Cell RNA - BJ [nTPM]":"12.6","Cell RNA - BJ hTERT+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.2","Cell RNA - CACO-2 [nTPM]":"6.5","Cell RNA - CAPAN-2 [nTPM]":"27.7","Cell RNA - Daudi [nTPM]":"12.1","Cell RNA - EFO-21 [nTPM]":"10.9","Cell RNA - fHDF\/TERT166 [nTPM]":"12.2","Cell RNA - GAMG [nTPM]":"12.9","Cell RNA - HaCaT [nTPM]":"8.1","Cell RNA - HAP1 [nTPM]":"28.2","Cell RNA - HBEC3-KT [nTPM]":"10.1","Cell RNA - HBF TERT88 [nTPM]":"24.8","Cell RNA - HDLM-2 [nTPM]":"10.7","Cell RNA - HEK 293 [nTPM]":"4.2","Cell RNA - HEL [nTPM]":"10.5","Cell RNA - HeLa [nTPM]":"3.6","Cell RNA - Hep G2 [nTPM]":"6.7","Cell RNA - HHSteC [nTPM]":"10.1","Cell RNA - HL-60 [nTPM]":"18.7","Cell RNA - HMC-1 [nTPM]":"16.1","Cell RNA - HSkMC [nTPM]":"5.9","Cell RNA - hTCEpi [nTPM]":"15.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.0","Cell RNA - hTERT-HME1 [nTPM]":"17.8","Cell RNA - hTERT-RPE1 [nTPM]":"5.2","Cell RNA - HUVEC TERT2 [nTPM]":"9.8","Cell RNA - JURKAT [nTPM]":"6.7","Cell RNA - K-562 [nTPM]":"22.7","Cell RNA - Karpas-707 [nTPM]":"21.3","Cell RNA - LHCN-M2 [nTPM]":"14.7","Cell RNA - MCF7 [nTPM]":"4.6","Cell RNA - MOLT-4 [nTPM]":"16.5","Cell RNA - NB-4 [nTPM]":"5.4","Cell RNA - NTERA-2 [nTPM]":"11.2","Cell RNA - OE19 [nTPM]":"5.7","Cell RNA - PC-3 [nTPM]":"4.0","Cell RNA - REH [nTPM]":"6.7","Cell RNA - RH-30 [nTPM]":"5.9","Cell RNA - RPMI-8226 [nTPM]":"22.2","Cell RNA - RPTEC TERT1 [nTPM]":"13.6","Cell RNA - RT4 [nTPM]":"5.3","Cell RNA - SCLC-21H [nTPM]":"13.4","Cell RNA - SH-SY5Y [nTPM]":"7.8","Cell RNA - SiHa [nTPM]":"7.5","Cell RNA - SK-BR-3 [nTPM]":"12.8","Cell RNA - SK-MEL-30 [nTPM]":"12.8","Cell RNA - SuSa [nTPM]":"6.6","Cell RNA - T-47d [nTPM]":"8.5","Cell RNA - THP-1 [nTPM]":"4.0","Cell RNA - TIME [nTPM]":"4.4","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"17.8","Cell RNA - U-2197 [nTPM]":"21.3","Cell RNA - U-251 MG [nTPM]":"7.8","Cell RNA - U-266\/70 [nTPM]":"16.3","Cell RNA - U-266\/84 [nTPM]":"23.5","Cell RNA - U-698 [nTPM]":"24.2","Cell RNA - U-87 MG [nTPM]":"11.2","Cell RNA - U-937 [nTPM]":"5.7","Cell RNA - WM-115 [nTPM]":"12.6","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"5.8","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"2.7","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"4.4","Blood RNA - non-classical monocyte [nTPM]":"3.1","Blood RNA - plasmacytoid DC [nTPM]":"3.5","Blood RNA - T-reg [nTPM]":"3.5","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"2.7","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"3.2","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"3.2","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"4.0","Single Cell Type RNA - Adipocytes [nTPM]":"24.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.1","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"65.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"85.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"45.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"131.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"60.3","Single Cell Type RNA - Bipolar cells [nTPM]":"33.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"61.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"51.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"58.6","Single Cell Type RNA - Club cells [nTPM]":"70.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"77.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"74.2","Single Cell Type RNA - dendritic cells [nTPM]":"52.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"52.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"72.4","Single Cell Type RNA - Ductal cells [nTPM]":"101.8","Single Cell Type RNA - Early spermatids [nTPM]":"12.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"41.8","Single Cell Type RNA - Endothelial cells [nTPM]":"35.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.0","Single Cell Type RNA - Erythroid cells [nTPM]":"256.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"77.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"131.0","Single Cell Type RNA - Fibroblasts [nTPM]":"39.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.3","Single Cell Type RNA - granulocytes [nTPM]":"57.8","Single Cell Type RNA - Granulosa cells [nTPM]":"24.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"159.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"110.9","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"94.2","Single Cell Type RNA - Ionocytes [nTPM]":"146.5","Single Cell Type RNA - Kupffer cells [nTPM]":"93.5","Single Cell Type RNA - Langerhans cells [nTPM]":"128.9","Single Cell Type RNA - Late spermatids [nTPM]":"6.9","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"66.4","Single Cell Type RNA - Melanocytes [nTPM]":"69.4","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"78.4","Single Cell Type RNA - Muller glia cells [nTPM]":"36.9","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"74.3","Single Cell Type RNA - Paneth cells [nTPM]":"88.5","Single Cell Type RNA - Peritubular cells [nTPM]":"33.8","Single Cell Type RNA - Plasma cells [nTPM]":"194.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"63.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"82.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"203.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"63.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.1","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.6","Single Cell Type RNA - Spermatocytes [nTPM]":"41.7","Single Cell Type RNA - Spermatogonia [nTPM]":"36.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"56.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"90.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"56.8","Single Cell Type RNA - T-cells [nTPM]":"54.0","Single Cell Type RNA - Theca cells [nTPM]":"33.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"68.6","Single Cell Type RNA - Urothelial cells [nTPM]":"53.9"},{"Gene":"CLEC16A","Gene synonym":["Gop-1","KIAA0350"],"Ensembl":"ENSG00000038532","Gene description":"C-type lectin domain containing 16A","Uniprot":["Q2KHT3"],"Chromosome":"16","Position":"10944564-11182186","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"130.9","Early spermatids":"118.7","Excitatory neurons":"93.3","Inhibitory neurons":"135.1","Late spermatids":"84.8","Oligodendrocyte precursor cells":"69.4","Oligodendrocytes":"72.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HDLM-2":"110.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035814","HPA035815","HPA061385"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035814":"AB_10600801","HPA035815":"AB_10671937","HPA061385":"AB_2684498"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.92e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"12.8","Tissue RNA - amygdala [nTPM]":"12.1","Tissue RNA - appendix [nTPM]":"7.2","Tissue RNA - basal ganglia [nTPM]":"13.4","Tissue RNA - bone marrow [nTPM]":"13.2","Tissue RNA - breast [nTPM]":"9.4","Tissue RNA - cerebellum [nTPM]":"16.7","Tissue RNA - cerebral cortex [nTPM]":"17.3","Tissue RNA - cervix [nTPM]":"11.2","Tissue RNA - choroid plexus [nTPM]":"23.6","Tissue RNA - colon [nTPM]":"9.5","Tissue RNA - duodenum [nTPM]":"8.2","Tissue RNA - endometrium 1 [nTPM]":"9.0","Tissue RNA - epididymis [nTPM]":"6.9","Tissue RNA - esophagus [nTPM]":"13.9","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"14.6","Tissue RNA - hippocampal formation [nTPM]":"11.3","Tissue RNA - hypothalamus [nTPM]":"11.1","Tissue RNA - kidney [nTPM]":"16.6","Tissue RNA - liver [nTPM]":"16.2","Tissue RNA - lung [nTPM]":"12.8","Tissue RNA - lymph node [nTPM]":"9.3","Tissue RNA - medulla oblongata [nTPM]":"13.8","Tissue RNA - midbrain [nTPM]":"14.5","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"8.9","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"17.3","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"11.3","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"11.5","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"5.7","Tissue RNA - skeletal muscle [nTPM]":"17.5","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"10.8","Tissue RNA - smooth muscle [nTPM]":"6.2","Tissue RNA - spinal cord [nTPM]":"9.7","Tissue RNA - spleen [nTPM]":"12.4","Tissue RNA - stomach 1 [nTPM]":"10.4","Tissue RNA - testis [nTPM]":"46.8","Tissue RNA - thalamus [nTPM]":"21.0","Tissue RNA - thymus [nTPM]":"10.9","Tissue RNA - thyroid gland [nTPM]":"13.3","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"8.8","Tissue RNA - urinary bladder [nTPM]":"9.1","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"11.7","Cell RNA - A-431 [nTPM]":"11.6","Cell RNA - A549 [nTPM]":"12.1","Cell RNA - AF22 [nTPM]":"9.0","Cell RNA - AN3-CA [nTPM]":"11.9","Cell RNA - ASC diff [nTPM]":"14.8","Cell RNA - ASC TERT1 [nTPM]":"10.3","Cell RNA - BEWO [nTPM]":"8.0","Cell RNA - BJ [nTPM]":"11.7","Cell RNA - BJ hTERT+ [nTPM]":"11.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.5","Cell RNA - CACO-2 [nTPM]":"13.5","Cell RNA - CAPAN-2 [nTPM]":"21.1","Cell RNA - Daudi [nTPM]":"22.8","Cell RNA - EFO-21 [nTPM]":"26.6","Cell RNA - fHDF\/TERT166 [nTPM]":"14.3","Cell RNA - GAMG [nTPM]":"10.6","Cell RNA - HaCaT [nTPM]":"10.1","Cell RNA - HAP1 [nTPM]":"11.6","Cell RNA - HBEC3-KT [nTPM]":"21.7","Cell RNA - HBF TERT88 [nTPM]":"12.3","Cell RNA - HDLM-2 [nTPM]":"110.3","Cell RNA - HEK 293 [nTPM]":"12.5","Cell RNA - HEL [nTPM]":"10.4","Cell RNA - HeLa [nTPM]":"16.4","Cell RNA - Hep G2 [nTPM]":"14.4","Cell RNA - HHSteC [nTPM]":"10.4","Cell RNA - HL-60 [nTPM]":"11.5","Cell RNA - HMC-1 [nTPM]":"21.5","Cell RNA - HSkMC [nTPM]":"12.3","Cell RNA - hTCEpi [nTPM]":"10.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.9","Cell RNA - hTERT-HME1 [nTPM]":"13.4","Cell RNA - hTERT-RPE1 [nTPM]":"8.8","Cell RNA - HUVEC TERT2 [nTPM]":"13.3","Cell RNA - JURKAT [nTPM]":"12.4","Cell RNA - K-562 [nTPM]":"17.6","Cell RNA - Karpas-707 [nTPM]":"13.8","Cell RNA - LHCN-M2 [nTPM]":"11.5","Cell RNA - MCF7 [nTPM]":"19.0","Cell RNA - MOLT-4 [nTPM]":"18.2","Cell RNA - NB-4 [nTPM]":"9.1","Cell RNA - NTERA-2 [nTPM]":"7.2","Cell RNA - OE19 [nTPM]":"10.0","Cell RNA - PC-3 [nTPM]":"9.5","Cell RNA - REH [nTPM]":"24.6","Cell RNA - RH-30 [nTPM]":"7.6","Cell RNA - RPMI-8226 [nTPM]":"13.5","Cell RNA - RPTEC TERT1 [nTPM]":"20.1","Cell RNA - RT4 [nTPM]":"8.4","Cell RNA - SCLC-21H [nTPM]":"11.5","Cell RNA - SH-SY5Y [nTPM]":"15.3","Cell RNA - SiHa [nTPM]":"16.8","Cell RNA - SK-BR-3 [nTPM]":"17.1","Cell RNA - SK-MEL-30 [nTPM]":"9.1","Cell RNA - SuSa [nTPM]":"10.4","Cell RNA - T-47d [nTPM]":"12.1","Cell RNA - THP-1 [nTPM]":"17.7","Cell RNA - TIME [nTPM]":"14.2","Cell RNA - U-138 MG [nTPM]":"12.4","Cell RNA - U-2 OS [nTPM]":"16.1","Cell RNA - U-2197 [nTPM]":"18.3","Cell RNA - U-251 MG [nTPM]":"10.4","Cell RNA - U-266\/70 [nTPM]":"9.7","Cell RNA - U-266\/84 [nTPM]":"9.2","Cell RNA - U-698 [nTPM]":"18.7","Cell RNA - U-87 MG [nTPM]":"15.5","Cell RNA - U-937 [nTPM]":"16.4","Cell RNA - WM-115 [nTPM]":"13.1","Blood RNA - basophil [nTPM]":"2.7","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"2.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"3.0","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"12.1","Brain RNA - basal ganglia [nTPM]":"13.4","Brain RNA - cerebellum [nTPM]":"16.7","Brain RNA - cerebral cortex [nTPM]":"17.3","Brain RNA - hippocampal formation [nTPM]":"11.3","Brain RNA - hypothalamus [nTPM]":"11.1","Brain RNA - medulla oblongata [nTPM]":"13.8","Brain RNA - midbrain [nTPM]":"14.5","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"9.7","Brain RNA - thalamus [nTPM]":"21.0","Brain RNA - white matter [nTPM]":"11.7","Single Cell Type RNA - Adipocytes [nTPM]":"7.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.0","Single Cell Type RNA - Astrocytes [nTPM]":"130.9","Single Cell Type RNA - B-cells [nTPM]":"12.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"11.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"8.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - dendritic cells [nTPM]":"5.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.0","Single Cell Type RNA - Early spermatids [nTPM]":"118.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"93.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.6","Single Cell Type RNA - Fibroblasts [nTPM]":"6.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.0","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"5.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"12.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.8","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"135.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.9","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.2","Single Cell Type RNA - Late spermatids [nTPM]":"84.8","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"6.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"8.6","Single Cell Type RNA - Muller glia cells [nTPM]":"3.9","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"69.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"72.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.5","Single Cell Type RNA - Paneth cells [nTPM]":"4.0","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"8.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"27.1","Single Cell Type RNA - Spermatogonia [nTPM]":"8.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - T-cells [nTPM]":"8.6","Single Cell Type RNA - Theca cells [nTPM]":"3.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.7","Single Cell Type RNA - Urothelial cells [nTPM]":"4.9"},{"Gene":"CTLA4","Gene synonym":["CD","CD152","CELIAC3","CTLA-4","GSE","IDDM12"],"Ensembl":"ENSG00000163599","Gene description":"Cytotoxic T-lymphocyte associated protein 4","Uniprot":["P16410"],"Chromosome":"2","Position":"203867771-203873965","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["Diabetes mellitus","Disease variant","FDA approved drug targets","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"37.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"T-cells":"41.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"T-reg":"44.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"445","RNA blood lineage specific nTPM":{"T-cells":"44.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"1.5","SK-MEL-30":"3.0","U-266\/70":"4.3","U-266\/84":"13.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.48e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"18.5","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"6.1","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"37.4","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"3.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"6.2","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"17.0","Tissue RNA - urinary bladder [nTPM]":"5.8","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"4.3","Cell RNA - U-266\/84 [nTPM]":"13.5","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"6.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"44.5","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"41.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CTSH","Gene synonym":["ACC-4","ACC-5","ACC4","ACC5","CPSB"],"Ensembl":"ENSG00000103811","Gene description":"Cathepsin H","Uniprot":["P09668"],"Chromosome":"15","Position":"78921058-78949574","Protein class":["Cancer-related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"349.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"1569.9","Proximal tubular cells":"523.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"208.5","intermediate monocyte":"137.7","memory B-cell":"83.3","myeloid DC":"183.6","naive B-cell":"56.0","non-classical monocyte":"94.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"83.3","dendritic cells":"183.6","monocytes":"208.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"306.4","HaCaT":"228.2","HDLM-2":"183.0","OE19":"197.4","RT4":"362.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000458","HPA003524"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol","Cytoplasmic bodies"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8700000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Vesicles","Cytosol","Cytoplasmic bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB000458":null,"HPA003524":"AB_1846075"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.90e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Tissue RNA - adipose tissue [nTPM]":"34.3","Tissue RNA - adrenal gland [nTPM]":"36.4","Tissue RNA - amygdala [nTPM]":"29.4","Tissue RNA - appendix [nTPM]":"100.6","Tissue RNA - basal ganglia [nTPM]":"30.2","Tissue RNA - bone marrow [nTPM]":"36.9","Tissue RNA - breast [nTPM]":"48.8","Tissue RNA - cerebellum [nTPM]":"29.9","Tissue RNA - cerebral cortex [nTPM]":"47.1","Tissue RNA - cervix [nTPM]":"112.8","Tissue RNA - choroid plexus [nTPM]":"31.4","Tissue RNA - colon [nTPM]":"32.5","Tissue RNA - duodenum [nTPM]":"77.8","Tissue RNA - endometrium 1 [nTPM]":"46.7","Tissue RNA - epididymis [nTPM]":"26.8","Tissue RNA - esophagus [nTPM]":"37.9","Tissue RNA - fallopian tube [nTPM]":"57.6","Tissue RNA - gallbladder [nTPM]":"104.6","Tissue RNA - heart muscle [nTPM]":"51.3","Tissue RNA - hippocampal formation [nTPM]":"29.6","Tissue RNA - hypothalamus [nTPM]":"32.9","Tissue RNA - kidney [nTPM]":"238.2","Tissue RNA - liver [nTPM]":"89.5","Tissue RNA - lung [nTPM]":"349.6","Tissue RNA - lymph node [nTPM]":"191.8","Tissue RNA - medulla oblongata [nTPM]":"30.8","Tissue RNA - midbrain [nTPM]":"31.4","Tissue RNA - ovary [nTPM]":"30.0","Tissue RNA - pancreas [nTPM]":"75.5","Tissue RNA - parathyroid gland [nTPM]":"77.6","Tissue RNA - pituitary gland [nTPM]":"10.1","Tissue RNA - placenta [nTPM]":"25.7","Tissue RNA - pons [nTPM]":"31.5","Tissue RNA - prostate [nTPM]":"59.7","Tissue RNA - rectum [nTPM]":"27.3","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"63.0","Tissue RNA - seminal vesicle [nTPM]":"70.7","Tissue RNA - skeletal muscle [nTPM]":"16.3","Tissue RNA - skin 1 [nTPM]":"48.4","Tissue RNA - small intestine [nTPM]":"56.7","Tissue RNA - smooth muscle [nTPM]":"43.1","Tissue RNA - spinal cord [nTPM]":"30.7","Tissue RNA - spleen [nTPM]":"51.8","Tissue RNA - stomach 1 [nTPM]":"93.9","Tissue RNA - testis [nTPM]":"10.1","Tissue RNA - thalamus [nTPM]":"32.7","Tissue RNA - thymus [nTPM]":"51.8","Tissue RNA - thyroid gland [nTPM]":"27.7","Tissue RNA - tongue [nTPM]":"37.7","Tissue RNA - tonsil [nTPM]":"131.3","Tissue RNA - urinary bladder [nTPM]":"202.2","Tissue RNA - vagina [nTPM]":"30.6","Tissue RNA - white matter [nTPM]":"32.4","Cell RNA - A-431 [nTPM]":"122.0","Cell RNA - A549 [nTPM]":"10.0","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"30.5","Cell RNA - ASC diff [nTPM]":"5.4","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"8.6","Cell RNA - BJ hTERT+ [nTPM]":"3.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.0","Cell RNA - CACO-2 [nTPM]":"17.6","Cell RNA - CAPAN-2 [nTPM]":"306.4","Cell RNA - Daudi [nTPM]":"34.6","Cell RNA - EFO-21 [nTPM]":"12.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"13.5","Cell RNA - HaCaT [nTPM]":"228.2","Cell RNA - HAP1 [nTPM]":"5.2","Cell RNA - HBEC3-KT [nTPM]":"52.6","Cell RNA - HBF TERT88 [nTPM]":"10.1","Cell RNA - HDLM-2 [nTPM]":"183.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"3.0","Cell RNA - HeLa [nTPM]":"1.3","Cell RNA - Hep G2 [nTPM]":"38.4","Cell RNA - HHSteC [nTPM]":"12.1","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"7.1","Cell RNA - HSkMC [nTPM]":"5.6","Cell RNA - hTCEpi [nTPM]":"10.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"59.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.0","Cell RNA - JURKAT [nTPM]":"5.9","Cell RNA - K-562 [nTPM]":"76.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"17.9","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"32.6","Cell RNA - NB-4 [nTPM]":"87.8","Cell RNA - NTERA-2 [nTPM]":"8.9","Cell RNA - OE19 [nTPM]":"197.4","Cell RNA - PC-3 [nTPM]":"4.9","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"5.9","Cell RNA - RPTEC TERT1 [nTPM]":"49.9","Cell RNA - RT4 [nTPM]":"362.1","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"5.2","Cell RNA - SiHa [nTPM]":"41.5","Cell RNA - SK-BR-3 [nTPM]":"27.8","Cell RNA - SK-MEL-30 [nTPM]":"75.4","Cell RNA - SuSa [nTPM]":"10.1","Cell RNA - T-47d [nTPM]":"12.5","Cell RNA - THP-1 [nTPM]":"48.0","Cell RNA - TIME [nTPM]":"16.4","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"6.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"5.3","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"92.4","Cell RNA - U-698 [nTPM]":"19.5","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"89.2","Cell RNA - WM-115 [nTPM]":"12.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"208.5","Blood RNA - eosinophil [nTPM]":"2.0","Blood RNA - gdT-cell [nTPM]":"7.6","Blood RNA - intermediate monocyte [nTPM]":"137.7","Blood RNA - MAIT T-cell [nTPM]":"29.7","Blood RNA - memory B-cell [nTPM]":"83.3","Blood RNA - memory CD4 T-cell [nTPM]":"20.5","Blood RNA - memory CD8 T-cell [nTPM]":"7.4","Blood RNA - myeloid DC [nTPM]":"183.6","Blood RNA - naive B-cell [nTPM]":"56.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.8","Blood RNA - neutrophil [nTPM]":"8.7","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"94.8","Blood RNA - plasmacytoid DC [nTPM]":"22.9","Blood RNA - T-reg [nTPM]":"18.3","Blood RNA - total PBMC [nTPM]":"147.5","Brain RNA - amygdala [nTPM]":"29.4","Brain RNA - basal ganglia [nTPM]":"30.2","Brain RNA - cerebellum [nTPM]":"29.9","Brain RNA - cerebral cortex [nTPM]":"47.1","Brain RNA - hippocampal formation [nTPM]":"29.6","Brain RNA - hypothalamus [nTPM]":"32.9","Brain RNA - medulla oblongata [nTPM]":"30.8","Brain RNA - midbrain [nTPM]":"31.4","Brain RNA - pons [nTPM]":"31.5","Brain RNA - spinal cord [nTPM]":"30.7","Brain RNA - thalamus [nTPM]":"32.7","Brain RNA - white matter [nTPM]":"32.4","Single Cell Type RNA - Adipocytes [nTPM]":"169.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"237.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1569.9","Single Cell Type RNA - Astrocytes [nTPM]":"59.1","Single Cell Type RNA - B-cells [nTPM]":"127.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"280.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"363.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"1.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"358.9","Single Cell Type RNA - Club cells [nTPM]":"258.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"367.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.8","Single Cell Type RNA - dendritic cells [nTPM]":"8.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"84.1","Single Cell Type RNA - Ductal cells [nTPM]":"225.0","Single Cell Type RNA - Early spermatids [nTPM]":"25.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"67.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"86.0","Single Cell Type RNA - Endothelial cells [nTPM]":"124.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"142.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.6","Single Cell Type RNA - Fibroblasts [nTPM]":"53.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"106.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.8","Single Cell Type RNA - granulocytes [nTPM]":"32.8","Single Cell Type RNA - Granulosa cells [nTPM]":"2.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.3","Single Cell Type RNA - Hepatocytes [nTPM]":"115.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"256.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.6","Single Cell Type RNA - Ionocytes [nTPM]":"101.7","Single Cell Type RNA - Kupffer cells [nTPM]":"177.8","Single Cell Type RNA - Langerhans cells [nTPM]":"259.6","Single Cell Type RNA - Late spermatids [nTPM]":"22.6","Single Cell Type RNA - Leydig cells [nTPM]":"73.0","Single Cell Type RNA - Macrophages [nTPM]":"350.4","Single Cell Type RNA - Melanocytes [nTPM]":"80.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"360.9","Single Cell Type RNA - Muller glia cells [nTPM]":"22.6","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"84.6","Single Cell Type RNA - Paneth cells [nTPM]":"16.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"155.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"112.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"153.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"523.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"261.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.3","Single Cell Type RNA - Spermatocytes [nTPM]":"12.3","Single Cell Type RNA - Spermatogonia [nTPM]":"56.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"41.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.4","Single Cell Type RNA - T-cells [nTPM]":"29.4","Single Cell Type RNA - Theca cells [nTPM]":"17.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"40.1","Single Cell Type RNA - Urothelial cells [nTPM]":"340.4"},{"Gene":"CYP27B1","Gene synonym":["CYP1","P450c1","PDDR","VDD1"],"Ensembl":"ENSG00000111012","Gene description":"Cytochrome P450 family 27 subfamily B member 1","Uniprot":["O15528"],"Chromosome":"12","Position":"57762334-57768986","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"15.2","thyroid gland":"5.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Exocrine glandular cells":"22.1","monocytes":"22.8","Proximal tubular cells":"36.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"MAIT T-cell":"1.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"T-cells":"1.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"13.6","RH-30":"22.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.79e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"15.2","Tissue RNA - liver [nTPM]":"0.6","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"3.3","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"5.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"2.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"2.8","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"3.7","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"2.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"3.3","Cell RNA - HAP1 [nTPM]":"0.5","Cell RNA - HBEC3-KT [nTPM]":"5.9","Cell RNA - HBF TERT88 [nTPM]":"3.1","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.9","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"1.2","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"13.6","Cell RNA - hTERT-RPE1 [nTPM]":"1.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"2.6","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"2.8","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"22.6","Cell RNA - RPMI-8226 [nTPM]":"1.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"2.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"1.7","Cell RNA - THP-1 [nTPM]":"2.3","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"1.1","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"1.2","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"2.6","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"22.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"EIF2AK3","Gene synonym":["PEK","PERK"],"Ensembl":"ENSG00000172071","Gene description":"Eukaryotic translation initiation factor 2 alpha kinase 3","Uniprot":["Q9NZJ5"],"Chromosome":"2","Position":"88556741-88627464","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Stress response","Translation regulation","Unfolded protein response"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"19.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"121.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"46.8","U-266\/70":"44.0","U-698":"31.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009204","HPA015737"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009204":"AB_2230863","HPA015737":"AB_1848062"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"1.9","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"1.9","Tissue RNA - pancreas [nTPM]":"19.6","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"9.7","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"5.0","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"1.5","Tissue RNA - spleen [nTPM]":"3.1","Tissue RNA - stomach 1 [nTPM]":"12.3","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"1.9","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"3.3","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"4.3","Cell RNA - ASC diff [nTPM]":"2.8","Cell RNA - ASC TERT1 [nTPM]":"2.0","Cell RNA - BEWO [nTPM]":"15.9","Cell RNA - BJ [nTPM]":"12.4","Cell RNA - BJ hTERT+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.1","Cell RNA - CACO-2 [nTPM]":"3.5","Cell RNA - CAPAN-2 [nTPM]":"2.9","Cell RNA - Daudi [nTPM]":"46.8","Cell RNA - EFO-21 [nTPM]":"8.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"3.1","Cell RNA - HaCaT [nTPM]":"7.2","Cell RNA - HAP1 [nTPM]":"1.6","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"25.3","Cell RNA - HEK 293 [nTPM]":"7.1","Cell RNA - HEL [nTPM]":"4.6","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"2.0","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"3.9","Cell RNA - HMC-1 [nTPM]":"12.3","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"1.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"2.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"4.9","Cell RNA - K-562 [nTPM]":"3.0","Cell RNA - Karpas-707 [nTPM]":"8.7","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"4.4","Cell RNA - MOLT-4 [nTPM]":"5.5","Cell RNA - NB-4 [nTPM]":"2.2","Cell RNA - NTERA-2 [nTPM]":"6.2","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"7.2","Cell RNA - REH [nTPM]":"25.1","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"8.2","Cell RNA - RPTEC TERT1 [nTPM]":"1.3","Cell RNA - RT4 [nTPM]":"5.0","Cell RNA - SCLC-21H [nTPM]":"5.6","Cell RNA - SH-SY5Y [nTPM]":"9.9","Cell RNA - SiHa [nTPM]":"6.3","Cell RNA - SK-BR-3 [nTPM]":"6.5","Cell RNA - SK-MEL-30 [nTPM]":"8.2","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"4.4","Cell RNA - TIME [nTPM]":"3.9","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"5.5","Cell RNA - U-2197 [nTPM]":"10.8","Cell RNA - U-251 MG [nTPM]":"7.1","Cell RNA - U-266\/70 [nTPM]":"44.0","Cell RNA - U-266\/84 [nTPM]":"24.4","Cell RNA - U-698 [nTPM]":"31.0","Cell RNA - U-87 MG [nTPM]":"4.6","Cell RNA - U-937 [nTPM]":"4.2","Cell RNA - WM-115 [nTPM]":"6.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"1.5","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"9.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"43.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Bipolar cells [nTPM]":"8.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"13.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.3","Single Cell Type RNA - Endothelial cells [nTPM]":"7.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.7","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.9","Single Cell Type RNA - Fibroblasts [nTPM]":"15.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"11.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.1","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.1","Single Cell Type RNA - Langerhans cells [nTPM]":"41.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"27.7","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"3.0","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.0","Single Cell Type RNA - Paneth cells [nTPM]":"7.7","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"121.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"3.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.8","Single Cell Type RNA - Urothelial cells [nTPM]":"16.6"},{"Gene":"ENPP1","Gene synonym":["M6S1","NPPS","PC-1","PCA1","PDNP1"],"Ensembl":"ENSG00000197594","Gene description":"Ectonucleotide pyrophosphatase\/phosphodiesterase 1","Uniprot":["P22413"],"Chromosome":"6","Position":"131808016-131895155","Protein class":["CD markers","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Biomineralization"],"Molecular function":["Hydrolase"],"Disease involvement":["Diabetes mellitus","Disease variant","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"44.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"80.2","Fibroblasts":"56.9","Hepatocytes":"111.6","Peritubular cells":"70.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"34.1","LHCN-M2":"21.1","U-138 MG":"27.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032904","HPA062066"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4400000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB032904":"AB_2099635","HPA062066":"AB_2684674"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.4","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"7.1","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"2.3","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"22.1","Tissue RNA - epididymis [nTPM]":"7.4","Tissue RNA - esophagus [nTPM]":"2.3","Tissue RNA - fallopian tube [nTPM]":"6.9","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"4.2","Tissue RNA - liver [nTPM]":"31.9","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"28.5","Tissue RNA - parathyroid gland [nTPM]":"27.8","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"44.0","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"10.2","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"20.1","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"2.7","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"34.1","Cell RNA - ASC TERT1 [nTPM]":"5.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"9.2","Cell RNA - BJ hTERT+ [nTPM]":"9.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.5","Cell RNA - CACO-2 [nTPM]":"4.1","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"5.9","Cell RNA - GAMG [nTPM]":"7.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"14.8","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"12.0","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"4.2","Cell RNA - HSkMC [nTPM]":"8.8","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.6","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.3","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"21.1","Cell RNA - MCF7 [nTPM]":"2.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"7.9","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"10.2","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"4.2","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"3.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"2.9","Cell RNA - U-138 MG [nTPM]":"27.6","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"1.9","Cell RNA - U-251 MG [nTPM]":"9.1","Cell RNA - U-266\/70 [nTPM]":"3.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"12.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.5","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"80.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"56.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"111.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"25.1","Single Cell Type RNA - Macrophages [nTPM]":"3.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"3.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"3.9","Single Cell Type RNA - Peritubular cells [nTPM]":"70.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"1.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"ERBB3","Gene synonym":["HER3","LCCS2"],"Ensembl":"ENSG00000065361","Gene description":"Erb-b2 receptor tyrosine kinase 3","Uniprot":["P21860"],"Chromosome":"12","Position":"56076799-56103505","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"254.3","Oligodendrocytes":"187.0","Paneth cells":"184.6","Proximal enterocytes":"240.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"2.4","neutrophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"116.4","OE19":"119.1","RT4":"89.7","SK-BR-3":"106.5","SK-MEL-30":"149.5","T-47d":"122.2","WM-115":"153.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025331","HPA045396","HPA070524"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB025331":null,"HPA045396":"AB_2679312","HPA070524":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.4","Tissue RNA - adrenal gland [nTPM]":"2.6","Tissue RNA - amygdala [nTPM]":"34.4","Tissue RNA - appendix [nTPM]":"8.0","Tissue RNA - basal ganglia [nTPM]":"69.2","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"56.5","Tissue RNA - cerebellum [nTPM]":"45.9","Tissue RNA - cerebral cortex [nTPM]":"62.0","Tissue RNA - cervix [nTPM]":"20.9","Tissue RNA - choroid plexus [nTPM]":"10.9","Tissue RNA - colon [nTPM]":"62.9","Tissue RNA - duodenum [nTPM]":"88.5","Tissue RNA - endometrium 1 [nTPM]":"5.5","Tissue RNA - epididymis [nTPM]":"12.3","Tissue RNA - esophagus [nTPM]":"82.0","Tissue RNA - fallopian tube [nTPM]":"12.1","Tissue RNA - gallbladder [nTPM]":"30.6","Tissue RNA - heart muscle [nTPM]":"9.0","Tissue RNA - hippocampal formation [nTPM]":"39.2","Tissue RNA - hypothalamus [nTPM]":"43.1","Tissue RNA - kidney [nTPM]":"36.2","Tissue RNA - liver [nTPM]":"98.6","Tissue RNA - lung [nTPM]":"29.3","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"59.4","Tissue RNA - midbrain [nTPM]":"54.4","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"57.0","Tissue RNA - parathyroid gland [nTPM]":"23.8","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"13.0","Tissue RNA - pons [nTPM]":"54.7","Tissue RNA - prostate [nTPM]":"37.8","Tissue RNA - rectum [nTPM]":"64.1","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"83.0","Tissue RNA - seminal vesicle [nTPM]":"18.2","Tissue RNA - skeletal muscle [nTPM]":"2.4","Tissue RNA - skin 1 [nTPM]":"75.7","Tissue RNA - small intestine [nTPM]":"82.5","Tissue RNA - smooth muscle [nTPM]":"3.8","Tissue RNA - spinal cord [nTPM]":"36.2","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"74.7","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"55.9","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"12.5","Tissue RNA - urinary bladder [nTPM]":"21.8","Tissue RNA - vagina [nTPM]":"44.2","Tissue RNA - white matter [nTPM]":"104.9","Cell RNA - A-431 [nTPM]":"39.8","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"3.2","Cell RNA - AN3-CA [nTPM]":"1.4","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"63.2","Cell RNA - BJ [nTPM]":"3.9","Cell RNA - BJ hTERT+ [nTPM]":"7.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"20.4","Cell RNA - CAPAN-2 [nTPM]":"70.4","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"32.2","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"7.7","Cell RNA - HBF TERT88 [nTPM]":"2.3","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"3.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"116.4","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"1.3","Cell RNA - hTCEpi [nTPM]":"9.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"2.6","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"71.6","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"10.4","Cell RNA - OE19 [nTPM]":"119.1","Cell RNA - PC-3 [nTPM]":"1.9","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"7.4","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"7.9","Cell RNA - RT4 [nTPM]":"89.7","Cell RNA - SCLC-21H [nTPM]":"3.3","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"106.5","Cell RNA - SK-MEL-30 [nTPM]":"149.5","Cell RNA - SuSa [nTPM]":"9.1","Cell RNA - T-47d [nTPM]":"122.2","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"4.0","Cell RNA - U-2197 [nTPM]":"1.9","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"153.4","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"34.4","Brain RNA - basal ganglia [nTPM]":"69.2","Brain RNA - cerebellum [nTPM]":"45.9","Brain RNA - cerebral cortex [nTPM]":"62.0","Brain RNA - hippocampal formation [nTPM]":"39.2","Brain RNA - hypothalamus [nTPM]":"43.1","Brain RNA - medulla oblongata [nTPM]":"59.4","Brain RNA - midbrain [nTPM]":"54.4","Brain RNA - pons [nTPM]":"54.7","Brain RNA - spinal cord [nTPM]":"36.2","Brain RNA - thalamus [nTPM]":"55.9","Brain RNA - white matter [nTPM]":"104.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"118.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"81.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"1.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"106.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"47.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"171.6","Single Cell Type RNA - Club cells [nTPM]":"74.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"52.6","Single Cell Type RNA - dendritic cells [nTPM]":"2.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"254.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"60.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"93.1","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"88.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"84.6","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"96.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"95.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"112.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"145.2","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.7","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"187.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"94.8","Single Cell Type RNA - Paneth cells [nTPM]":"184.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"103.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"240.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"54.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.4","Single Cell Type RNA - Spermatocytes [nTPM]":"9.5","Single Cell Type RNA - Spermatogonia [nTPM]":"13.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"87.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"100.6","Single Cell Type RNA - T-cells [nTPM]":"2.5","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"136.9","Single Cell Type RNA - Urothelial cells [nTPM]":"135.4"},{"Gene":"FOXP3","Gene synonym":["AIID","DIETER","IPEX","JM2","PIDX","SCURFIN","XPID"],"Ensembl":"ENSG00000049768","Gene description":"Forkhead box P3","Uniprot":["Q9BZS1"],"Chromosome":"X","Position":"49250438-49270477","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"7.2","lymphoid tissue":"7.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"1.3","Hepatocytes":"1.4","Horizontal cells":"3.3","Melanocytes":"1.8","T-cells":"5.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"T-reg":"53.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"394","RNA blood lineage specific nTPM":{"T-cells":"53.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"2.9","MCF7":"5.2","SiHa":"4.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026301","HPA045943"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB026301":null,"HPA045943":"AB_2679508"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.91e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.02e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.90e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"7.4","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"6.1","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"2.4","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"7.2","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"2.8","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"2.9","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"1.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.9","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"5.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"4.7","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"2.0","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"1.4","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"53.3","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"5.3","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"FTO","Gene synonym":["ALKBH9","KIAA1752","MGC5149"],"Ensembl":"ENSG00000140718","Gene description":"FTO alpha-ketoglutarate dependent dioxygenase","Uniprot":["Q9C0B1"],"Chromosome":"16","Position":"53701692-54158512","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase","Transferase"],"Disease involvement":["Disease variant","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"173.3","Excitatory neurons":"226.1","Inhibitory neurons":"240.7","Oligodendrocyte precursor cells":"210.6","Oligodendrocytes":"282.5","Respiratory ciliated cells":"182.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017123","HPA041086","HPA068695"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"540000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB017123":null,"HPA041086":"AB_2677293","HPA068695":"AB_2732117"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"},"Tissue RNA - adipose tissue [nTPM]":"24.4","Tissue RNA - adrenal gland [nTPM]":"33.6","Tissue RNA - amygdala [nTPM]":"31.8","Tissue RNA - appendix [nTPM]":"12.5","Tissue RNA - basal ganglia [nTPM]":"36.6","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"36.3","Tissue RNA - cerebellum [nTPM]":"30.1","Tissue RNA - cerebral cortex [nTPM]":"37.7","Tissue RNA - cervix [nTPM]":"25.8","Tissue RNA - choroid plexus [nTPM]":"31.0","Tissue RNA - colon [nTPM]":"22.2","Tissue RNA - duodenum [nTPM]":"7.7","Tissue RNA - endometrium 1 [nTPM]":"26.9","Tissue RNA - epididymis [nTPM]":"21.4","Tissue RNA - esophagus [nTPM]":"17.2","Tissue RNA - fallopian tube [nTPM]":"25.3","Tissue RNA - gallbladder [nTPM]":"21.6","Tissue RNA - heart muscle [nTPM]":"27.1","Tissue RNA - hippocampal formation [nTPM]":"35.2","Tissue RNA - hypothalamus [nTPM]":"39.5","Tissue RNA - kidney [nTPM]":"25.0","Tissue RNA - liver [nTPM]":"17.4","Tissue RNA - lung [nTPM]":"36.8","Tissue RNA - lymph node [nTPM]":"15.0","Tissue RNA - medulla oblongata [nTPM]":"29.2","Tissue RNA - midbrain [nTPM]":"31.3","Tissue RNA - ovary [nTPM]":"27.2","Tissue RNA - pancreas [nTPM]":"20.7","Tissue RNA - parathyroid gland [nTPM]":"40.6","Tissue RNA - pituitary gland [nTPM]":"26.2","Tissue RNA - placenta [nTPM]":"20.1","Tissue RNA - pons [nTPM]":"31.9","Tissue RNA - prostate [nTPM]":"20.0","Tissue RNA - rectum [nTPM]":"14.1","Tissue RNA - retina [nTPM]":"38.4","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"23.9","Tissue RNA - skeletal muscle [nTPM]":"33.1","Tissue RNA - skin 1 [nTPM]":"21.4","Tissue RNA - small intestine [nTPM]":"12.5","Tissue RNA - smooth muscle [nTPM]":"29.9","Tissue RNA - spinal cord [nTPM]":"30.5","Tissue RNA - spleen [nTPM]":"16.4","Tissue RNA - stomach 1 [nTPM]":"15.0","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"33.8","Tissue RNA - thymus [nTPM]":"17.0","Tissue RNA - thyroid gland [nTPM]":"27.5","Tissue RNA - tongue [nTPM]":"23.0","Tissue RNA - tonsil [nTPM]":"14.8","Tissue RNA - urinary bladder [nTPM]":"21.9","Tissue RNA - vagina [nTPM]":"18.5","Tissue RNA - white matter [nTPM]":"43.9","Cell RNA - A-431 [nTPM]":"15.1","Cell RNA - A549 [nTPM]":"26.8","Cell RNA - AF22 [nTPM]":"35.0","Cell RNA - AN3-CA [nTPM]":"35.9","Cell RNA - ASC diff [nTPM]":"67.3","Cell RNA - ASC TERT1 [nTPM]":"50.4","Cell RNA - BEWO [nTPM]":"11.5","Cell RNA - BJ [nTPM]":"35.6","Cell RNA - BJ hTERT+ [nTPM]":"32.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.5","Cell RNA - CACO-2 [nTPM]":"16.8","Cell RNA - CAPAN-2 [nTPM]":"19.3","Cell RNA - Daudi [nTPM]":"34.4","Cell RNA - EFO-21 [nTPM]":"38.2","Cell RNA - fHDF\/TERT166 [nTPM]":"46.3","Cell RNA - GAMG [nTPM]":"16.6","Cell RNA - HaCaT [nTPM]":"21.7","Cell RNA - HAP1 [nTPM]":"32.4","Cell RNA - HBEC3-KT [nTPM]":"34.9","Cell RNA - HBF TERT88 [nTPM]":"42.5","Cell RNA - HDLM-2 [nTPM]":"16.0","Cell RNA - HEK 293 [nTPM]":"25.5","Cell RNA - HEL [nTPM]":"15.5","Cell RNA - HeLa [nTPM]":"33.6","Cell RNA - Hep G2 [nTPM]":"31.7","Cell RNA - HHSteC [nTPM]":"46.2","Cell RNA - HL-60 [nTPM]":"12.5","Cell RNA - HMC-1 [nTPM]":"17.1","Cell RNA - HSkMC [nTPM]":"55.9","Cell RNA - hTCEpi [nTPM]":"36.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.6","Cell RNA - hTERT-HME1 [nTPM]":"32.5","Cell RNA - hTERT-RPE1 [nTPM]":"36.6","Cell RNA - HUVEC TERT2 [nTPM]":"44.1","Cell RNA - JURKAT [nTPM]":"25.1","Cell RNA - K-562 [nTPM]":"15.2","Cell RNA - Karpas-707 [nTPM]":"8.4","Cell RNA - LHCN-M2 [nTPM]":"48.1","Cell RNA - MCF7 [nTPM]":"11.8","Cell RNA - MOLT-4 [nTPM]":"28.0","Cell RNA - NB-4 [nTPM]":"19.2","Cell RNA - NTERA-2 [nTPM]":"18.1","Cell RNA - OE19 [nTPM]":"15.5","Cell RNA - PC-3 [nTPM]":"17.5","Cell RNA - REH [nTPM]":"42.2","Cell RNA - RH-30 [nTPM]":"52.9","Cell RNA - RPMI-8226 [nTPM]":"32.3","Cell RNA - RPTEC TERT1 [nTPM]":"44.6","Cell RNA - RT4 [nTPM]":"12.3","Cell RNA - SCLC-21H [nTPM]":"43.0","Cell RNA - SH-SY5Y [nTPM]":"29.7","Cell RNA - SiHa [nTPM]":"40.4","Cell RNA - SK-BR-3 [nTPM]":"23.6","Cell RNA - SK-MEL-30 [nTPM]":"10.8","Cell RNA - SuSa [nTPM]":"33.7","Cell RNA - T-47d [nTPM]":"31.1","Cell RNA - THP-1 [nTPM]":"29.3","Cell RNA - TIME [nTPM]":"42.4","Cell RNA - U-138 MG [nTPM]":"36.4","Cell RNA - U-2 OS [nTPM]":"23.9","Cell RNA - U-2197 [nTPM]":"19.8","Cell RNA - U-251 MG [nTPM]":"22.1","Cell RNA - U-266\/70 [nTPM]":"15.9","Cell RNA - U-266\/84 [nTPM]":"13.9","Cell RNA - U-698 [nTPM]":"35.0","Cell RNA - U-87 MG [nTPM]":"33.9","Cell RNA - U-937 [nTPM]":"22.9","Cell RNA - WM-115 [nTPM]":"28.7","Blood RNA - basophil [nTPM]":"14.9","Blood RNA - classical monocyte [nTPM]":"17.9","Blood RNA - eosinophil [nTPM]":"9.7","Blood RNA - gdT-cell [nTPM]":"25.6","Blood RNA - intermediate monocyte [nTPM]":"22.7","Blood RNA - MAIT T-cell [nTPM]":"32.4","Blood RNA - memory B-cell [nTPM]":"17.6","Blood RNA - memory CD4 T-cell [nTPM]":"24.4","Blood RNA - memory CD8 T-cell [nTPM]":"25.9","Blood RNA - myeloid DC [nTPM]":"23.8","Blood RNA - naive B-cell [nTPM]":"17.4","Blood RNA - naive CD4 T-cell [nTPM]":"22.5","Blood RNA - naive CD8 T-cell [nTPM]":"24.4","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"26.4","Blood RNA - non-classical monocyte [nTPM]":"16.5","Blood RNA - plasmacytoid DC [nTPM]":"9.5","Blood RNA - T-reg [nTPM]":"26.6","Blood RNA - total PBMC [nTPM]":"23.1","Brain RNA - amygdala [nTPM]":"31.8","Brain RNA - basal ganglia [nTPM]":"36.6","Brain RNA - cerebellum [nTPM]":"30.1","Brain RNA - cerebral cortex [nTPM]":"37.7","Brain RNA - hippocampal formation [nTPM]":"35.2","Brain RNA - hypothalamus [nTPM]":"39.5","Brain RNA - medulla oblongata [nTPM]":"29.2","Brain RNA - midbrain [nTPM]":"31.3","Brain RNA - pons [nTPM]":"31.9","Brain RNA - spinal cord [nTPM]":"30.5","Brain RNA - thalamus [nTPM]":"33.8","Brain RNA - white matter [nTPM]":"43.9","Single Cell Type RNA - Adipocytes [nTPM]":"15.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"62.0","Single Cell Type RNA - Astrocytes [nTPM]":"173.3","Single Cell Type RNA - B-cells [nTPM]":"10.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"22.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"69.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"54.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.0","Single Cell Type RNA - Early spermatids [nTPM]":"39.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.3","Single Cell Type RNA - Endothelial cells [nTPM]":"17.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.6","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"226.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"23.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.9","Single Cell Type RNA - granulocytes [nTPM]":"25.9","Single Cell Type RNA - Granulosa cells [nTPM]":"16.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"13.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"240.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.0","Single Cell Type RNA - Langerhans cells [nTPM]":"13.2","Single Cell Type RNA - Late spermatids [nTPM]":"69.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"11.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"134.0","Single Cell Type RNA - monocytes [nTPM]":"5.5","Single Cell Type RNA - Muller glia cells [nTPM]":"19.6","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"210.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"282.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.5","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"18.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"182.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"17.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.3","Single Cell Type RNA - Urothelial cells [nTPM]":"7.9"},{"Gene":"GCK","Gene synonym":["HK4","MODY2"],"Ensembl":"ENSG00000106633","Gene description":"Glucokinase","Uniprot":["P35557"],"Chromosome":"7","Position":"44143213-44198170","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Allosteric enzyme","Kinase","Transferase"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"12.6","choroid plexus":"7.4","heart muscle":"8.8","liver":"21.5","pituitary gland":"23.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"5.0","Cardiomyocytes":"4.9","Fibroblasts":"5.2","Horizontal cells":"5.0","Smooth muscle cells":"3.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"4.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"2.3","naive CD4 T-cell":"2.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SCLC-21H":"6.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007034","HPA007093"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007034":"AB_1079050","HPA007093":"AB_1079051"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"8.1","Tissue RNA - cerebral cortex [nTPM]":"9.5","Tissue RNA - cervix [nTPM]":"2.8","Tissue RNA - choroid plexus [nTPM]":"7.4","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"8.8","Tissue RNA - hippocampal formation [nTPM]":"8.2","Tissue RNA - hypothalamus [nTPM]":"11.0","Tissue RNA - kidney [nTPM]":"1.2","Tissue RNA - liver [nTPM]":"21.5","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"9.9","Tissue RNA - ovary [nTPM]":"1.4","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"23.9","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"9.1","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"8.3","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"2.0","Tissue RNA - white matter [nTPM]":"7.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"6.6","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"8.1","Brain RNA - cerebral cortex [nTPM]":"9.5","Brain RNA - hippocampal formation [nTPM]":"8.2","Brain RNA - hypothalamus [nTPM]":"11.0","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"9.9","Brain RNA - pons [nTPM]":"9.1","Brain RNA - spinal cord [nTPM]":"8.3","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"7.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"5.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"GLIS3","Gene synonym":["MGC33662","ZNF515"],"Ensembl":"ENSG00000107249","Gene description":"GLIS family zinc finger 3","Uniprot":["Q8NEA6"],"Chromosome":"9","Position":"3824127-4348392","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Congenital hypothyroidism","Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"24.2","choroid plexus":"20.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"649.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"21.5","HSkMC":"29.5","RPTEC TERT1":"20.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056426"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA056426":"AB_2683128"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"2.1","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"7.8","Tissue RNA - choroid plexus [nTPM]":"20.5","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"8.7","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"5.4","Tissue RNA - hypothalamus [nTPM]":"10.8","Tissue RNA - kidney [nTPM]":"7.8","Tissue RNA - liver [nTPM]":"3.3","Tissue RNA - lung [nTPM]":"3.8","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"24.2","Tissue RNA - midbrain [nTPM]":"18.0","Tissue RNA - ovary [nTPM]":"6.6","Tissue RNA - pancreas [nTPM]":"9.7","Tissue RNA - parathyroid gland [nTPM]":"2.4","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"3.3","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"8.2","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"1.5","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"13.7","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"1.8","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"18.6","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"2.4","Tissue RNA - white matter [nTPM]":"13.2","Cell RNA - A-431 [nTPM]":"1.0","Cell RNA - A549 [nTPM]":"8.5","Cell RNA - AF22 [nTPM]":"2.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"3.7","Cell RNA - ASC TERT1 [nTPM]":"9.5","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"21.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.4","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"3.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.3","Cell RNA - fHDF\/TERT166 [nTPM]":"5.5","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"2.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"6.7","Cell RNA - HDLM-2 [nTPM]":"2.5","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"11.0","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"29.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.8","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"2.9","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.5","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"5.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"20.8","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"5.5","Cell RNA - U-138 MG [nTPM]":"3.4","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"3.2","Cell RNA - U-251 MG [nTPM]":"13.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"8.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.4","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"5.4","Brain RNA - hypothalamus [nTPM]":"10.8","Brain RNA - medulla oblongata [nTPM]":"24.2","Brain RNA - midbrain [nTPM]":"18.0","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"13.7","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"13.2","Single Cell Type RNA - Adipocytes [nTPM]":"8.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.0","Single Cell Type RNA - Astrocytes [nTPM]":"649.7","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"75.8","Single Cell Type RNA - Club cells [nTPM]":"34.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"69.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"51.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"79.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.5","Single Cell Type RNA - Endothelial cells [nTPM]":"11.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"21.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"82.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"8.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"3.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"86.2","Single Cell Type RNA - monocytes [nTPM]":"2.2","Single Cell Type RNA - Muller glia cells [nTPM]":"15.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.9","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"8.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.6","Single Cell Type RNA - Urothelial cells [nTPM]":"6.1"},{"Gene":"HHEX","Gene synonym":["HEX","HOX11L-PEN","PRHX"],"Ensembl":"ENSG00000152804","Gene description":"Hematopoietically expressed homeobox","Uniprot":["Q03014"],"Chromosome":"10","Position":"92689955-92695647","Protein class":["Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Developmental protein","DNA-binding","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"84.7","liver":"91.2","thyroid gland":"102.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"77.2","Cholangiocytes":"125.8","dendritic cells":"57.6","Ductal cells":"107.9","Endothelial cells":"80.0","Hepatic stellate cells":"88.9","Hepatocytes":"58.3","Hofbauer cells":"72.6","Kupffer cells":"63.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"20.1","thyroid cancer":"56.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"43","RNA blood cell specific nTPM":{"basophil":"28.0","classical monocyte":"41.5","eosinophil":"61.8","intermediate monocyte":"45.7","memory B-cell":"59.3","myeloid DC":"30.8","naive B-cell":"65.8","neutrophil":"31.4","non-classical monocyte":"50.7","plasmacytoid DC":"36.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"87.7","HEL":"99.9","HMC-1":"105.6","HUVEC TERT2":"106.1","K-562":"154.8","NB-4":"101.8","U-937":"79.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003257","HPA051894"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA003257":null,"HPA051894":"AB_2681653"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.83e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.91e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.23e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.25e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.2","Tissue RNA - adrenal gland [nTPM]":"18.5","Tissue RNA - amygdala [nTPM]":"5.0","Tissue RNA - appendix [nTPM]":"22.2","Tissue RNA - basal ganglia [nTPM]":"5.4","Tissue RNA - bone marrow [nTPM]":"84.7","Tissue RNA - breast [nTPM]":"11.2","Tissue RNA - cerebellum [nTPM]":"5.6","Tissue RNA - cerebral cortex [nTPM]":"8.8","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"7.8","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"4.1","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"27.4","Tissue RNA - heart muscle [nTPM]":"6.1","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"5.2","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"91.2","Tissue RNA - lung [nTPM]":"16.9","Tissue RNA - lymph node [nTPM]":"39.1","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"3.0","Tissue RNA - pancreas [nTPM]":"38.1","Tissue RNA - parathyroid gland [nTPM]":"1.9","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"14.6","Tissue RNA - pons [nTPM]":"6.4","Tissue RNA - prostate [nTPM]":"4.7","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"3.5","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"19.0","Tissue RNA - smooth muscle [nTPM]":"5.8","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"39.9","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"102.1","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"30.4","Tissue RNA - urinary bladder [nTPM]":"12.7","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"6.7","Cell RNA - A-431 [nTPM]":"11.2","Cell RNA - A549 [nTPM]":"20.6","Cell RNA - AF22 [nTPM]":"10.5","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.9","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"5.6","Cell RNA - BJ hTERT+ [nTPM]":"46.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.6","Cell RNA - CACO-2 [nTPM]":"4.0","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"10.7","Cell RNA - EFO-21 [nTPM]":"87.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"2.1","Cell RNA - HAP1 [nTPM]":"9.5","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"9.1","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"11.1","Cell RNA - HEL [nTPM]":"99.9","Cell RNA - HeLa [nTPM]":"8.8","Cell RNA - Hep G2 [nTPM]":"67.4","Cell RNA - HHSteC [nTPM]":"21.0","Cell RNA - HL-60 [nTPM]":"58.6","Cell RNA - HMC-1 [nTPM]":"105.6","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.5","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.7","Cell RNA - HUVEC TERT2 [nTPM]":"106.1","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"154.8","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"101.8","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"30.2","Cell RNA - PC-3 [nTPM]":"11.8","Cell RNA - REH [nTPM]":"34.0","Cell RNA - RH-30 [nTPM]":"3.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"4.3","Cell RNA - SCLC-21H [nTPM]":"4.9","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"6.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"3.3","Cell RNA - THP-1 [nTPM]":"30.6","Cell RNA - TIME [nTPM]":"37.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"2.6","Cell RNA - U-266\/84 [nTPM]":"1.8","Cell RNA - U-698 [nTPM]":"21.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"79.7","Cell RNA - WM-115 [nTPM]":"51.4","Blood RNA - basophil [nTPM]":"28.0","Blood RNA - classical monocyte [nTPM]":"41.5","Blood RNA - eosinophil [nTPM]":"61.8","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"45.7","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"59.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"30.8","Blood RNA - naive B-cell [nTPM]":"65.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"31.4","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"50.7","Blood RNA - plasmacytoid DC [nTPM]":"36.3","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"15.5","Brain RNA - amygdala [nTPM]":"5.0","Brain RNA - basal ganglia [nTPM]":"5.4","Brain RNA - cerebellum [nTPM]":"5.6","Brain RNA - cerebral cortex [nTPM]":"8.8","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"5.2","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"6.4","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"6.7","Single Cell Type RNA - Adipocytes [nTPM]":"31.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"77.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"125.8","Single Cell Type RNA - Club cells [nTPM]":"1.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"57.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"107.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"80.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.3","Single Cell Type RNA - Erythroid cells [nTPM]":"28.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"88.9","Single Cell Type RNA - Hepatocytes [nTPM]":"58.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"72.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"63.5","Single Cell Type RNA - Langerhans cells [nTPM]":"29.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"51.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"50.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"6.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"8.3","Single Cell Type RNA - Theca cells [nTPM]":"3.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"HLA-DQA1","Gene synonym":["CELIAC1","HLA-DQA"],"Ensembl":"ENSG00000196735","Gene description":"Major histocompatibility complex, class II, DQ alpha 1","Uniprot":["P01909"],"Chromosome":"6","Position":"32628179-32647062","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"333.9","lymphoid tissue":"335.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Langerhans cells":"4114.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"666.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"B-cells":"287.6","dendritic cells":"666.6","monocytes":"257.6"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"HDLM-2":"1419.1"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012315"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012315":"AB_1853930"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Tissue RNA - adipose tissue [nTPM]":"61.7","Tissue RNA - adrenal gland [nTPM]":"45.7","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"111.0","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"7.1","Tissue RNA - breast [nTPM]":"41.6","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"49.9","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"76.8","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"27.7","Tissue RNA - epididymis [nTPM]":"32.2","Tissue RNA - esophagus [nTPM]":"32.1","Tissue RNA - fallopian tube [nTPM]":"29.1","Tissue RNA - gallbladder [nTPM]":"127.4","Tissue RNA - heart muscle [nTPM]":"20.8","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"39.6","Tissue RNA - liver [nTPM]":"95.1","Tissue RNA - lung [nTPM]":"333.9","Tissue RNA - lymph node [nTPM]":"335.8","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"18.6","Tissue RNA - pancreas [nTPM]":"15.0","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"15.2","Tissue RNA - placenta [nTPM]":"13.7","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"115.8","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"34.8","Tissue RNA - seminal vesicle [nTPM]":"7.8","Tissue RNA - skeletal muscle [nTPM]":"7.5","Tissue RNA - skin 1 [nTPM]":"30.0","Tissue RNA - small intestine [nTPM]":"74.0","Tissue RNA - smooth muscle [nTPM]":"19.2","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"180.0","Tissue RNA - stomach 1 [nTPM]":"103.3","Tissue RNA - testis [nTPM]":"12.2","Tissue RNA - thalamus [nTPM]":"3.4","Tissue RNA - thymus [nTPM]":"234.3","Tissue RNA - thyroid gland [nTPM]":"26.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"322.3","Tissue RNA - urinary bladder [nTPM]":"175.9","Tissue RNA - vagina [nTPM]":"16.3","Tissue RNA - white matter [nTPM]":"11.1","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"213.6","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1419.1","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"4.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"63.2","Cell RNA - U-266\/84 [nTPM]":"1.5","Cell RNA - U-698 [nTPM]":"156.1","Cell RNA - U-87 MG [nTPM]":"24.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"105.8","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"257.6","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"287.6","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"16.5","Blood RNA - myeloid DC [nTPM]":"666.6","Blood RNA - naive B-cell [nTPM]":"274.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"4.3","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"8.2","Blood RNA - non-classical monocyte [nTPM]":"68.3","Blood RNA - plasmacytoid DC [nTPM]":"162.7","Blood RNA - T-reg [nTPM]":"21.6","Blood RNA - total PBMC [nTPM]":"129.0","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"3.4","Brain RNA - white matter [nTPM]":"11.1","Single Cell Type RNA - Adipocytes [nTPM]":"67.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"86.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"972.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"28.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"19.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"179.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"97.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"38.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.4","Single Cell Type RNA - Fibroblasts [nTPM]":"14.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"50.4","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"381.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"518.6","Single Cell Type RNA - Langerhans cells [nTPM]":"4114.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"874.3","Single Cell Type RNA - Melanocytes [nTPM]":"71.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"957.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"96.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - T-cells [nTPM]":"56.0","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.7","Single Cell Type RNA - Urothelial cells [nTPM]":"7.6"},{"Gene":"HLA-DQA2","Gene synonym":["HLA-DXA"],"Ensembl":"ENSG00000237541","Gene description":"Major histocompatibility complex, class II, DQ alpha 2","Uniprot":["P01906"],"Chromosome":"6","Position":"32741391-32747198","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"20.8","lymphoid tissue":"27.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Langerhans cells":"1196.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.9","Tissue RNA - adrenal gland [nTPM]":"4.5","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"7.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"3.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.9","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"20.8","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"2.5","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"3.4","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"8.4","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"27.1","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"3.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"46.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"179.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"7.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"144.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"20.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"110.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"78.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1196.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"243.1","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"125.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"13.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"HLA-DQB1","Gene synonym":["CELIAC1","HLA-DQB","IDDM1"],"Ensembl":"ENSG00000179344","Gene description":"Major histocompatibility complex, class II, DQ beta 1","Uniprot":[],"Chromosome":"6","Position":"32659467-32668383","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"179.1","lymphoid tissue":"301.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"995.1","Langerhans cells":"4144.8","Macrophages":"1090.5","monocytes":"1038.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"153.5","intermediate monocyte":"142.9","memory B-cell":"159.2","myeloid DC":"386.3","naive B-cell":"169.1","plasmacytoid DC":"116.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"169.1","dendritic cells":"386.3","monocytes":"153.5"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"HDLM-2":"599.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013667"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Rods & Rings"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA013667":"AB_1853932"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"56.6","Tissue RNA - adrenal gland [nTPM]":"23.9","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"77.8","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"40.0","Tissue RNA - breast [nTPM]":"45.3","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"45.8","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"18.9","Tissue RNA - epididymis [nTPM]":"126.9","Tissue RNA - esophagus [nTPM]":"21.3","Tissue RNA - fallopian tube [nTPM]":"22.2","Tissue RNA - gallbladder [nTPM]":"43.6","Tissue RNA - heart muscle [nTPM]":"21.6","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"34.3","Tissue RNA - liver [nTPM]":"37.1","Tissue RNA - lung [nTPM]":"179.1","Tissue RNA - lymph node [nTPM]":"301.8","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"3.8","Tissue RNA - ovary [nTPM]":"7.4","Tissue RNA - pancreas [nTPM]":"14.3","Tissue RNA - parathyroid gland [nTPM]":"10.6","Tissue RNA - pituitary gland [nTPM]":"21.3","Tissue RNA - placenta [nTPM]":"10.1","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"17.1","Tissue RNA - rectum [nTPM]":"39.0","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"24.2","Tissue RNA - seminal vesicle [nTPM]":"11.9","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"31.8","Tissue RNA - small intestine [nTPM]":"78.0","Tissue RNA - smooth muscle [nTPM]":"11.2","Tissue RNA - spinal cord [nTPM]":"4.6","Tissue RNA - spleen [nTPM]":"139.3","Tissue RNA - stomach 1 [nTPM]":"128.0","Tissue RNA - testis [nTPM]":"7.0","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"108.2","Tissue RNA - thyroid gland [nTPM]":"26.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"122.3","Tissue RNA - urinary bladder [nTPM]":"89.9","Tissue RNA - vagina [nTPM]":"16.9","Tissue RNA - white matter [nTPM]":"5.5","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"93.9","Cell RNA - EFO-21 [nTPM]":"2.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"19.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"19.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"599.9","Cell RNA - HEK 293 [nTPM]":"13.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"3.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"7.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"3.3","Cell RNA - THP-1 [nTPM]":"10.9","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"68.7","Cell RNA - U-266\/84 [nTPM]":"2.1","Cell RNA - U-698 [nTPM]":"66.0","Cell RNA - U-87 MG [nTPM]":"47.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"153.5","Blood RNA - eosinophil [nTPM]":"27.9","Blood RNA - gdT-cell [nTPM]":"12.8","Blood RNA - intermediate monocyte [nTPM]":"142.9","Blood RNA - MAIT T-cell [nTPM]":"6.6","Blood RNA - memory B-cell [nTPM]":"159.2","Blood RNA - memory CD4 T-cell [nTPM]":"6.9","Blood RNA - memory CD8 T-cell [nTPM]":"20.0","Blood RNA - myeloid DC [nTPM]":"386.3","Blood RNA - naive B-cell [nTPM]":"169.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"6.3","Blood RNA - neutrophil [nTPM]":"11.8","Blood RNA - NK-cell [nTPM]":"10.4","Blood RNA - non-classical monocyte [nTPM]":"41.1","Blood RNA - plasmacytoid DC [nTPM]":"116.5","Blood RNA - T-reg [nTPM]":"41.1","Blood RNA - total PBMC [nTPM]":"217.0","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"3.8","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"4.6","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"5.5","Single Cell Type RNA - Adipocytes [nTPM]":"162.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"181.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"995.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"89.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"5.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"40.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"188.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"38.8","Single Cell Type RNA - Early spermatids [nTPM]":"16.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"135.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.8","Single Cell Type RNA - Erythroid cells [nTPM]":"37.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.0","Single Cell Type RNA - Fibroblasts [nTPM]":"18.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"38.5","Single Cell Type RNA - Granulosa cells [nTPM]":"7.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"422.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"487.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4144.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.5","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"1090.5","Single Cell Type RNA - Melanocytes [nTPM]":"97.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"1038.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.3","Single Cell Type RNA - Paneth cells [nTPM]":"27.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"86.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"417.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.6","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"66.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - T-cells [nTPM]":"84.5","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.1","Single Cell Type RNA - Urothelial cells [nTPM]":"49.1"},{"Gene":"HLA-DRB1","Gene synonym":["HLA-DR1B"],"Ensembl":"ENSG00000196126","Gene description":"Major histocompatibility complex, class II, DR beta 1","Uniprot":["P01911"],"Chromosome":"6","Position":"32578769-32589848","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"581.3","lymphoid tissue":"651.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"2149.9","Langerhans cells":"11630.1","Macrophages":"3622.3","monocytes":"3104.1","Proximal enterocytes":"1849.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"47.5"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"749.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"257.9","dendritic cells":"749.2","monocytes":"371.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"1181.9","HMC-1":"159.7","THP-1":"140.4","U-266\/70":"150.3","U-698":"202.5","U-87 MG":"308.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015400","CAB034021","HPA043151"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015400":"AB_784538","CAB034021":"AB_1124844","HPA043151":"AB_2678342"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"311.4","Tissue RNA - adrenal gland [nTPM]":"162.1","Tissue RNA - amygdala [nTPM]":"7.2","Tissue RNA - appendix [nTPM]":"220.8","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"61.3","Tissue RNA - breast [nTPM]":"239.4","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"47.5","Tissue RNA - cervix [nTPM]":"121.4","Tissue RNA - choroid plexus [nTPM]":"11.1","Tissue RNA - colon [nTPM]":"113.5","Tissue RNA - duodenum [nTPM]":"2.4","Tissue RNA - endometrium 1 [nTPM]":"90.3","Tissue RNA - epididymis [nTPM]":"140.6","Tissue RNA - esophagus [nTPM]":"71.7","Tissue RNA - fallopian tube [nTPM]":"119.4","Tissue RNA - gallbladder [nTPM]":"66.9","Tissue RNA - heart muscle [nTPM]":"134.6","Tissue RNA - hippocampal formation [nTPM]":"6.2","Tissue RNA - hypothalamus [nTPM]":"11.4","Tissue RNA - kidney [nTPM]":"217.5","Tissue RNA - liver [nTPM]":"100.6","Tissue RNA - lung [nTPM]":"581.3","Tissue RNA - lymph node [nTPM]":"651.4","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"7.1","Tissue RNA - ovary [nTPM]":"40.4","Tissue RNA - pancreas [nTPM]":"50.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"80.2","Tissue RNA - placenta [nTPM]":"13.6","Tissue RNA - pons [nTPM]":"6.9","Tissue RNA - prostate [nTPM]":"88.4","Tissue RNA - rectum [nTPM]":"135.3","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"93.8","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"58.3","Tissue RNA - skin 1 [nTPM]":"122.5","Tissue RNA - small intestine [nTPM]":"353.2","Tissue RNA - smooth muscle [nTPM]":"11.1","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"516.2","Tissue RNA - stomach 1 [nTPM]":"232.3","Tissue RNA - testis [nTPM]":"25.5","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"254.3","Tissue RNA - thyroid gland [nTPM]":"129.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"257.4","Tissue RNA - urinary bladder [nTPM]":"116.2","Tissue RNA - vagina [nTPM]":"91.5","Tissue RNA - white matter [nTPM]":"13.4","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"2.4","Cell RNA - EFO-21 [nTPM]":"17.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"4.7","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1181.9","Cell RNA - HEK 293 [nTPM]":"12.9","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"159.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"12.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"28.5","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"2.3","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"4.4","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"6.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"26.7","Cell RNA - SuSa [nTPM]":"1.5","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"140.4","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"150.3","Cell RNA - U-266\/84 [nTPM]":"4.4","Cell RNA - U-698 [nTPM]":"202.5","Cell RNA - U-87 MG [nTPM]":"308.9","Cell RNA - U-937 [nTPM]":"5.8","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"323.0","Blood RNA - eosinophil [nTPM]":"53.7","Blood RNA - gdT-cell [nTPM]":"12.2","Blood RNA - intermediate monocyte [nTPM]":"371.3","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"225.4","Blood RNA - memory CD4 T-cell [nTPM]":"9.0","Blood RNA - memory CD8 T-cell [nTPM]":"27.2","Blood RNA - myeloid DC [nTPM]":"749.2","Blood RNA - naive B-cell [nTPM]":"257.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"12.2","Blood RNA - neutrophil [nTPM]":"8.9","Blood RNA - NK-cell [nTPM]":"21.0","Blood RNA - non-classical monocyte [nTPM]":"223.8","Blood RNA - plasmacytoid DC [nTPM]":"147.6","Blood RNA - T-reg [nTPM]":"35.4","Blood RNA - total PBMC [nTPM]":"411.8","Brain RNA - amygdala [nTPM]":"7.2","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"47.5","Brain RNA - hippocampal formation [nTPM]":"6.2","Brain RNA - hypothalamus [nTPM]":"11.4","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"7.1","Brain RNA - pons [nTPM]":"6.9","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"13.4","Single Cell Type RNA - Adipocytes [nTPM]":"1241.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"147.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"609.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2149.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"173.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"78.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"96.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"150.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"90.1","Single Cell Type RNA - Club cells [nTPM]":"277.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"141.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"484.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"92.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"272.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.0","Single Cell Type RNA - Endothelial cells [nTPM]":"721.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.0","Single Cell Type RNA - Erythroid cells [nTPM]":"120.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"73.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.0","Single Cell Type RNA - Fibroblasts [nTPM]":"77.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"131.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.6","Single Cell Type RNA - granulocytes [nTPM]":"124.0","Single Cell Type RNA - Granulosa cells [nTPM]":"47.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"179.9","Single Cell Type RNA - Hepatocytes [nTPM]":"5.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1417.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"92.7","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"1755.3","Single Cell Type RNA - Langerhans cells [nTPM]":"11630.1","Single Cell Type RNA - Late spermatids [nTPM]":"12.3","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"3622.3","Single Cell Type RNA - Melanocytes [nTPM]":"217.1","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"3104.1","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"89.1","Single Cell Type RNA - Paneth cells [nTPM]":"308.9","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"120.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1849.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"218.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"357.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"47.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"147.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - T-cells [nTPM]":"245.6","Single Cell Type RNA - Theca cells [nTPM]":"52.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"152.2","Single Cell Type RNA - Urothelial cells [nTPM]":"125.5"},{"Gene":"HNF1A","Gene synonym":["HNF1","LFB1","MODY3","TCF1"],"Ensembl":"ENSG00000135100","Gene description":"HNF1 homeobox A","Uniprot":[],"Chromosome":"12","Position":"120978543-121002512","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"15.4","kidney":"16.7","liver":"34.7","pancreas":"9.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"14.5","Hepatocytes":"15.8","Intestinal goblet cells":"9.4","Paneth cells":"14.8","Proximal enterocytes":"33.4","Proximal tubular cells":"16.0","Undifferentiated cells":"10.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"4.5","liver cancer":"3.6","pancreatic cancer":"1.4","renal cancer":"3.6","stomach cancer":"4.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"A549":"8.9","CACO-2":"29.4","Hep G2":"32.5","OE19":"15.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010430","HPA035231"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB010430":"AB_2116746","HPA035231":"AB_2674528"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"5.5","Tissue RNA - duodenum [nTPM]":"15.4","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"16.7","Tissue RNA - liver [nTPM]":"34.7","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"14.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"8.9","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"29.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"32.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"15.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"3.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"15.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.9","Single Cell Type RNA - Paneth cells [nTPM]":"14.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"HNF1B","Gene synonym":["HNF1beta","LFB3","MODY5","TCF2","VHNF1"],"Ensembl":"ENSG00000275410","Gene description":"HNF1 homeobox B","Uniprot":["P35680"],"Chromosome":"17","Position":"37686431-37745105","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"61.1","pancreas":"33.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"78.6","Collecting duct cells":"57.0","Distal tubular cells":"45.0","Ductal cells":"42.0","Early spermatids":"32.3","Glandular and luminal cells":"41.7","Pancreatic endocrine cells":"31.7","Proximal tubular cells":"38.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"32.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"RPTEC TERT1":"139.3"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"2.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002083","CAB068192"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB068192":"AB_2665649","HPA002083":"AB_1080232"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.00e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.51e-6"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"9.9","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"5.7","Tissue RNA - gallbladder [nTPM]":"15.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"61.1","Tissue RNA - liver [nTPM]":"12.9","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"33.0","Tissue RNA - parathyroid gland [nTPM]":"3.5","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"7.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"4.4","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"8.6","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"8.2","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"3.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"19.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"21.7","Cell RNA - CAPAN-2 [nTPM]":"2.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"28.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"4.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"3.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"139.3","Cell RNA - RT4 [nTPM]":"3.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"78.6","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"57.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"45.0","Single Cell Type RNA - Ductal cells [nTPM]":"42.0","Single Cell Type RNA - Early spermatids [nTPM]":"32.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.7","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"11.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.7","Single Cell Type RNA - Paneth cells [nTPM]":"11.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.4","Single Cell Type RNA - Urothelial cells [nTPM]":"2.7"},{"Gene":"HNF4A","Gene synonym":["HNF4","MODY","MODY1","NR2A1","TCF14"],"Ensembl":"ENSG00000101076","Gene description":"Hepatocyte nuclear factor 4 alpha","Uniprot":["P41235"],"Chromosome":"20","Position":"44355700-44434596","Protein class":["Disease related genes","Human disease related genes","Nuclear receptors","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Receptor","Repressor"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"102.4","kidney":"43.3","liver":"117.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"232.6","Hepatocytes":"186.8","Intestinal goblet cells":"69.8","Paneth cells":"120.0","Proximal enterocytes":"153.9","Proximal tubular cells":"170.1","Undifferentiated cells":"136.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"48.2","liver cancer":"38.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"CACO-2":"154.4","Hep G2":"114.8","OE19":"42.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004712","CAB019417"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB019417":"AB_2295208","HPA004712":"AB_1079075"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"5.9","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"8.4","Tissue RNA - colon [nTPM]":"58.6","Tissue RNA - duodenum [nTPM]":"102.4","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"43.3","Tissue RNA - liver [nTPM]":"117.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"25.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"44.1","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"82.6","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"22.6","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"14.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"154.4","Cell RNA - CAPAN-2 [nTPM]":"6.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"114.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"42.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"232.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"7.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.9","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"186.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"69.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"18.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.0","Single Cell Type RNA - Paneth cells [nTPM]":"120.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"153.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"170.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"136.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"IFIH1","Gene synonym":["Hlcd","IDDM19","MDA-5","MDA5"],"Ensembl":"ENSG00000115267","Gene description":"Interferon induced with helicase C domain 1","Uniprot":["Q9BYX4"],"Chromosome":"2","Position":"162267074-162318684","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Helicase","Hydrolase","RNA-binding"],"Disease involvement":["Aicardi-Goutieres syndrome","Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"38.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"55.6","Late spermatids":"53.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+":"62.3","BJ hTERT+ SV40 Large T+ RasG12V":"71.5","Karpas-707":"38.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002656"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002656":"AB_1079344"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.2","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"12.7","Tissue RNA - basal ganglia [nTPM]":"4.3","Tissue RNA - bone marrow [nTPM]":"38.1","Tissue RNA - breast [nTPM]":"5.9","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"7.4","Tissue RNA - duodenum [nTPM]":"13.1","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"9.5","Tissue RNA - heart muscle [nTPM]":"5.1","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"8.5","Tissue RNA - lung [nTPM]":"10.9","Tissue RNA - lymph node [nTPM]":"11.7","Tissue RNA - medulla oblongata [nTPM]":"7.2","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"7.0","Tissue RNA - pancreas [nTPM]":"7.1","Tissue RNA - parathyroid gland [nTPM]":"8.1","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"8.3","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"17.5","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"10.0","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"16.4","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"10.9","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"6.7","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"7.4","Cell RNA - ASC TERT1 [nTPM]":"6.0","Cell RNA - BEWO [nTPM]":"2.8","Cell RNA - BJ [nTPM]":"1.2","Cell RNA - BJ hTERT+ [nTPM]":"17.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"62.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"71.5","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"16.7","Cell RNA - Daudi [nTPM]":"13.3","Cell RNA - EFO-21 [nTPM]":"10.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"31.9","Cell RNA - HaCaT [nTPM]":"8.5","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"6.3","Cell RNA - HDLM-2 [nTPM]":"35.4","Cell RNA - HEK 293 [nTPM]":"4.5","Cell RNA - HEL [nTPM]":"7.1","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"2.8","Cell RNA - HHSteC [nTPM]":"5.0","Cell RNA - HL-60 [nTPM]":"8.2","Cell RNA - HMC-1 [nTPM]":"6.4","Cell RNA - HSkMC [nTPM]":"5.3","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.9","Cell RNA - hTERT-HME1 [nTPM]":"1.7","Cell RNA - hTERT-RPE1 [nTPM]":"6.5","Cell RNA - HUVEC TERT2 [nTPM]":"4.9","Cell RNA - JURKAT [nTPM]":"6.9","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"38.9","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"12.5","Cell RNA - MOLT-4 [nTPM]":"9.3","Cell RNA - NB-4 [nTPM]":"6.4","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"5.4","Cell RNA - PC-3 [nTPM]":"3.8","Cell RNA - REH [nTPM]":"7.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"18.8","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"7.3","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"3.7","Cell RNA - SK-BR-3 [nTPM]":"20.7","Cell RNA - SK-MEL-30 [nTPM]":"34.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"5.7","Cell RNA - THP-1 [nTPM]":"7.1","Cell RNA - TIME [nTPM]":"4.1","Cell RNA - U-138 MG [nTPM]":"1.9","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"1.1","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"15.2","Cell RNA - U-266\/84 [nTPM]":"26.8","Cell RNA - U-698 [nTPM]":"1.9","Cell RNA - U-87 MG [nTPM]":"3.5","Cell RNA - U-937 [nTPM]":"6.5","Cell RNA - WM-115 [nTPM]":"5.6","Blood RNA - basophil [nTPM]":"4.4","Blood RNA - classical monocyte [nTPM]":"11.5","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"6.6","Blood RNA - intermediate monocyte [nTPM]":"12.5","Blood RNA - MAIT T-cell [nTPM]":"9.2","Blood RNA - memory B-cell [nTPM]":"12.4","Blood RNA - memory CD4 T-cell [nTPM]":"8.2","Blood RNA - memory CD8 T-cell [nTPM]":"7.2","Blood RNA - myeloid DC [nTPM]":"11.1","Blood RNA - naive B-cell [nTPM]":"12.8","Blood RNA - naive CD4 T-cell [nTPM]":"6.7","Blood RNA - naive CD8 T-cell [nTPM]":"6.9","Blood RNA - neutrophil [nTPM]":"15.2","Blood RNA - NK-cell [nTPM]":"4.0","Blood RNA - non-classical monocyte [nTPM]":"12.7","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"10.3","Blood RNA - total PBMC [nTPM]":"7.8","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"4.3","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"7.2","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"24.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"20.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"11.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.4","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"18.7","Single Cell Type RNA - Early spermatids [nTPM]":"55.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.9","Single Cell Type RNA - Endothelial cells [nTPM]":"22.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.7","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.5","Single Cell Type RNA - Fibroblasts [nTPM]":"8.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.2","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"6.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.5","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.8","Single Cell Type RNA - Langerhans cells [nTPM]":"8.7","Single Cell Type RNA - Late spermatids [nTPM]":"53.3","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"20.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"23.9","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.4","Single Cell Type RNA - Paneth cells [nTPM]":"10.1","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"16.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"13.1","Single Cell Type RNA - Theca cells [nTPM]":"6.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.7","Single Cell Type RNA - Urothelial cells [nTPM]":"11.1"},{"Gene":"IGF2BP2","Gene synonym":["IMP-2"],"Ensembl":"ENSG00000073792","Gene description":"Insulin like growth factor 2 mRNA binding protein 2","Uniprot":["Q9Y6M1"],"Chromosome":"3","Position":"185643130-185825042","Protein class":["Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["mRNA transport","Translation regulation","Transport"],"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"126.6","Glandular and luminal cells":"117.7","Rod photoreceptor cells":"176.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"2.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"263.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017126","HPA035145"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB017126":null,"HPA035145":"AB_2674491"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.12e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.37e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.0","Tissue RNA - adrenal gland [nTPM]":"9.0","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"11.9","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"2.0","Tissue RNA - cervix [nTPM]":"7.2","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"12.6","Tissue RNA - duodenum [nTPM]":"15.0","Tissue RNA - endometrium 1 [nTPM]":"5.0","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"3.3","Tissue RNA - fallopian tube [nTPM]":"11.2","Tissue RNA - gallbladder [nTPM]":"7.5","Tissue RNA - heart muscle [nTPM]":"9.0","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"11.7","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"6.6","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"15.1","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"14.9","Tissue RNA - retina [nTPM]":"22.3","Tissue RNA - salivary gland [nTPM]":"9.3","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"4.4","Tissue RNA - small intestine [nTPM]":"16.0","Tissue RNA - smooth muscle [nTPM]":"4.6","Tissue RNA - spinal cord [nTPM]":"1.5","Tissue RNA - spleen [nTPM]":"4.4","Tissue RNA - stomach 1 [nTPM]":"13.2","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"3.4","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"3.8","Tissue RNA - vagina [nTPM]":"5.5","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"129.4","Cell RNA - A549 [nTPM]":"11.0","Cell RNA - AF22 [nTPM]":"124.2","Cell RNA - AN3-CA [nTPM]":"22.5","Cell RNA - ASC diff [nTPM]":"64.8","Cell RNA - ASC TERT1 [nTPM]":"102.5","Cell RNA - BEWO [nTPM]":"73.2","Cell RNA - BJ [nTPM]":"68.5","Cell RNA - BJ hTERT+ [nTPM]":"94.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"102.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"121.6","Cell RNA - CACO-2 [nTPM]":"94.1","Cell RNA - CAPAN-2 [nTPM]":"36.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"98.2","Cell RNA - fHDF\/TERT166 [nTPM]":"56.9","Cell RNA - GAMG [nTPM]":"130.1","Cell RNA - HaCaT [nTPM]":"57.7","Cell RNA - HAP1 [nTPM]":"58.4","Cell RNA - HBEC3-KT [nTPM]":"97.3","Cell RNA - HBF TERT88 [nTPM]":"163.9","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"58.2","Cell RNA - HEL [nTPM]":"37.7","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"64.1","Cell RNA - HHSteC [nTPM]":"140.2","Cell RNA - HL-60 [nTPM]":"1.2","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"75.0","Cell RNA - hTCEpi [nTPM]":"50.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"67.6","Cell RNA - hTERT-HME1 [nTPM]":"263.9","Cell RNA - hTERT-RPE1 [nTPM]":"53.2","Cell RNA - HUVEC TERT2 [nTPM]":"95.3","Cell RNA - JURKAT [nTPM]":"10.1","Cell RNA - K-562 [nTPM]":"37.6","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"75.2","Cell RNA - MCF7 [nTPM]":"1.1","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"27.8","Cell RNA - NTERA-2 [nTPM]":"87.3","Cell RNA - OE19 [nTPM]":"22.1","Cell RNA - PC-3 [nTPM]":"45.7","Cell RNA - REH [nTPM]":"13.5","Cell RNA - RH-30 [nTPM]":"48.1","Cell RNA - RPMI-8226 [nTPM]":"38.8","Cell RNA - RPTEC TERT1 [nTPM]":"63.7","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"7.7","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"5.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"113.5","Cell RNA - SuSa [nTPM]":"120.5","Cell RNA - T-47d [nTPM]":"10.1","Cell RNA - THP-1 [nTPM]":"82.1","Cell RNA - TIME [nTPM]":"144.8","Cell RNA - U-138 MG [nTPM]":"34.8","Cell RNA - U-2 OS [nTPM]":"74.8","Cell RNA - U-2197 [nTPM]":"44.6","Cell RNA - U-251 MG [nTPM]":"78.2","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"34.7","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"50.3","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"2.0","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"1.5","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"6.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.6","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"49.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"82.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"38.9","Single Cell Type RNA - Early spermatids [nTPM]":"126.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"86.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.8","Single Cell Type RNA - Endothelial cells [nTPM]":"18.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.6","Single Cell Type RNA - Erythroid cells [nTPM]":"46.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.0","Single Cell Type RNA - Fibroblasts [nTPM]":"25.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"117.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"64.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"39.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.7","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"8.8","Single Cell Type RNA - Langerhans cells [nTPM]":"16.9","Single Cell Type RNA - Late spermatids [nTPM]":"81.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"10.5","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"11.3","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"61.1","Single Cell Type RNA - Paneth cells [nTPM]":"80.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"63.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"68.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"74.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"176.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.7","Single Cell Type RNA - Spermatogonia [nTPM]":"14.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"45.9","Single Cell Type RNA - Urothelial cells [nTPM]":"77.8"},{"Gene":"IL2","Gene synonym":["IL-2","TCGF"],"Ensembl":"ENSG00000109471","Gene description":"Interleukin 2","Uniprot":["P60568"],"Chromosome":"4","Position":"122451470-122456725","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Cytokine","Growth factor"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Melanocytes":"3.6","T-cells":"13.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010310"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":20300,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010310":"AB_649346"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"13.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"IL21","Gene synonym":["IL-21","Za11"],"Ensembl":"ENSG00000138684","Gene description":"Interleukin 21","Uniprot":["Q9HBE4"],"Chromosome":"4","Position":"122610108-122621066","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lymphoid tissue":"5.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Early spermatids":"13.7","Late spermatids":"8.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":55700,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"5.9","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"13.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"IL2RA","Gene synonym":["CD25","IDDM10","IL2R"],"Ensembl":"ENSG00000134460","Gene description":"Interleukin 2 receptor subunit alpha","Uniprot":["P01589"],"Chromosome":"10","Position":"6010689-6062370","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"18.9","lymphoid tissue":"17.4","urinary bladder":"11.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"granulocytes":"80.8","monocytes":"177.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"175.9","T-reg":"248.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"granulocytes":"175.9","T-cells":"248.0"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"59","RNA cell line specific nTPM":{"HDLM-2":"1113.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002419","HPA054622"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"410000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002419":"AB_563538","HPA054622":"AB_2682546"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.08e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.9","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"14.2","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"1.1","Tissue RNA - colon [nTPM]":"3.3","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"2.6","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"2.9","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"17.4","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"6.5","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"7.5","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"11.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1113.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"18.9","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"175.9","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"20.1","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"14.7","Blood RNA - memory CD4 T-cell [nTPM]":"27.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"7.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"13.4","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"248.0","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"13.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"8.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"80.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"19.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"177.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"19.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"INS","Gene synonym":["IDDM1","IDDM2"],"Ensembl":"ENSG00000254647","Gene description":"Insulin","Uniprot":["P01308"],"Chromosome":"11","Position":"2159779-2161221","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism"],"Molecular function":["Hormone"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"135","RNA tissue specific nTPM":{"pancreas":"12983.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Pancreatic endocrine cells":"1475.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7165","RNA cancer specific FPKM":{"pancreatic cancer":"1751.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"EFO-21":"268.3","U-2 OS":"376.2","U-698":"132.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"13","RNA pig brain regional specific nTPM":{"midbrain":"1.3"},"Antibody":["CAB000048","HPA004932","CAB012098","CAB053843"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":437000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 9: U-2 OS - Unknown function","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000048":null,"CAB012098":"AB_300968","CAB053843":"AB_620123","HPA004932":"AB_1851816"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"19.2","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"49.8","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"12.8","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.8","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"5.6","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"40.7","Tissue RNA - liver [nTPM]":"1.4","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"12983.6","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"96.4","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"42.2","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"5.0","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"268.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"8.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"3.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"9.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"376.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"31.8","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"15.9","Cell RNA - U-698 [nTPM]":"132.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"9.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"12.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"67.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1475.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"INSR","Gene synonym":["CD220"],"Ensembl":"ENSG00000171105","Gene description":"Insulin receptor","Uniprot":["P06213"],"Chromosome":"19","Position":"7112255-7294414","Protein class":["CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Diabetes mellitus","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"9.8","granulocytes":"5.9","monocytes":"12.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"54.9","U-266\/70":"40.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036302","HPA036303"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA036302":"AB_2675048","HPA036303":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.0","Tissue RNA - adrenal gland [nTPM]":"22.6","Tissue RNA - amygdala [nTPM]":"12.5","Tissue RNA - appendix [nTPM]":"2.8","Tissue RNA - basal ganglia [nTPM]":"16.8","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"13.0","Tissue RNA - cerebellum [nTPM]":"17.3","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"14.6","Tissue RNA - choroid plexus [nTPM]":"18.8","Tissue RNA - colon [nTPM]":"15.0","Tissue RNA - duodenum [nTPM]":"10.0","Tissue RNA - endometrium 1 [nTPM]":"18.4","Tissue RNA - epididymis [nTPM]":"6.3","Tissue RNA - esophagus [nTPM]":"4.1","Tissue RNA - fallopian tube [nTPM]":"16.9","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"26.3","Tissue RNA - hippocampal formation [nTPM]":"10.0","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"21.8","Tissue RNA - liver [nTPM]":"33.0","Tissue RNA - lung [nTPM]":"7.2","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"18.3","Tissue RNA - midbrain [nTPM]":"16.3","Tissue RNA - ovary [nTPM]":"39.9","Tissue RNA - pancreas [nTPM]":"64.2","Tissue RNA - parathyroid gland [nTPM]":"13.0","Tissue RNA - pituitary gland [nTPM]":"16.3","Tissue RNA - placenta [nTPM]":"7.4","Tissue RNA - pons [nTPM]":"18.7","Tissue RNA - prostate [nTPM]":"15.2","Tissue RNA - rectum [nTPM]":"10.4","Tissue RNA - retina [nTPM]":"6.5","Tissue RNA - salivary gland [nTPM]":"16.9","Tissue RNA - seminal vesicle [nTPM]":"9.9","Tissue RNA - skeletal muscle [nTPM]":"23.5","Tissue RNA - skin 1 [nTPM]":"11.5","Tissue RNA - small intestine [nTPM]":"12.2","Tissue RNA - smooth muscle [nTPM]":"11.5","Tissue RNA - spinal cord [nTPM]":"14.1","Tissue RNA - spleen [nTPM]":"48.2","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"5.4","Tissue RNA - thalamus [nTPM]":"16.6","Tissue RNA - thymus [nTPM]":"2.7","Tissue RNA - thyroid gland [nTPM]":"14.5","Tissue RNA - tongue [nTPM]":"13.3","Tissue RNA - tonsil [nTPM]":"3.5","Tissue RNA - urinary bladder [nTPM]":"12.3","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"22.5","Cell RNA - A-431 [nTPM]":"6.2","Cell RNA - A549 [nTPM]":"3.2","Cell RNA - AF22 [nTPM]":"3.6","Cell RNA - AN3-CA [nTPM]":"5.7","Cell RNA - ASC diff [nTPM]":"18.8","Cell RNA - ASC TERT1 [nTPM]":"6.1","Cell RNA - BEWO [nTPM]":"11.1","Cell RNA - BJ [nTPM]":"3.5","Cell RNA - BJ hTERT+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"8.4","Cell RNA - CAPAN-2 [nTPM]":"7.0","Cell RNA - Daudi [nTPM]":"9.0","Cell RNA - EFO-21 [nTPM]":"8.2","Cell RNA - fHDF\/TERT166 [nTPM]":"6.8","Cell RNA - GAMG [nTPM]":"4.0","Cell RNA - HaCaT [nTPM]":"1.6","Cell RNA - HAP1 [nTPM]":"8.9","Cell RNA - HBEC3-KT [nTPM]":"1.4","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"6.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.3","Cell RNA - Hep G2 [nTPM]":"22.6","Cell RNA - HHSteC [nTPM]":"8.2","Cell RNA - HL-60 [nTPM]":"4.3","Cell RNA - HMC-1 [nTPM]":"6.7","Cell RNA - HSkMC [nTPM]":"10.0","Cell RNA - hTCEpi [nTPM]":"4.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"4.9","Cell RNA - hTERT-RPE1 [nTPM]":"4.2","Cell RNA - HUVEC TERT2 [nTPM]":"3.8","Cell RNA - JURKAT [nTPM]":"4.8","Cell RNA - K-562 [nTPM]":"9.5","Cell RNA - Karpas-707 [nTPM]":"54.9","Cell RNA - LHCN-M2 [nTPM]":"1.8","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"3.1","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"3.8","Cell RNA - PC-3 [nTPM]":"5.2","Cell RNA - REH [nTPM]":"29.0","Cell RNA - RH-30 [nTPM]":"2.1","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"27.8","Cell RNA - SCLC-21H [nTPM]":"6.6","Cell RNA - SH-SY5Y [nTPM]":"5.2","Cell RNA - SiHa [nTPM]":"6.5","Cell RNA - SK-BR-3 [nTPM]":"3.8","Cell RNA - SK-MEL-30 [nTPM]":"3.3","Cell RNA - SuSa [nTPM]":"6.4","Cell RNA - T-47d [nTPM]":"1.4","Cell RNA - THP-1 [nTPM]":"21.6","Cell RNA - TIME [nTPM]":"3.6","Cell RNA - U-138 MG [nTPM]":"3.4","Cell RNA - U-2 OS [nTPM]":"2.1","Cell RNA - U-2197 [nTPM]":"8.2","Cell RNA - U-251 MG [nTPM]":"5.1","Cell RNA - U-266\/70 [nTPM]":"40.4","Cell RNA - U-266\/84 [nTPM]":"23.9","Cell RNA - U-698 [nTPM]":"20.2","Cell RNA - U-87 MG [nTPM]":"4.3","Cell RNA - U-937 [nTPM]":"7.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"2.7","Blood RNA - classical monocyte [nTPM]":"8.6","Blood RNA - eosinophil [nTPM]":"5.9","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"8.8","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"9.8","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"12.5","Blood RNA - plasmacytoid DC [nTPM]":"8.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"12.5","Brain RNA - basal ganglia [nTPM]":"16.8","Brain RNA - cerebellum [nTPM]":"17.3","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"10.0","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"18.3","Brain RNA - midbrain [nTPM]":"16.3","Brain RNA - pons [nTPM]":"18.7","Brain RNA - spinal cord [nTPM]":"14.1","Brain RNA - thalamus [nTPM]":"16.6","Brain RNA - white matter [nTPM]":"22.5","Single Cell Type RNA - Adipocytes [nTPM]":"75.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.7","Single Cell Type RNA - Astrocytes [nTPM]":"64.9","Single Cell Type RNA - B-cells [nTPM]":"10.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"64.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"63.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"40.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"134.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"76.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"92.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"137.2","Single Cell Type RNA - Club cells [nTPM]":"83.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"79.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.8","Single Cell Type RNA - dendritic cells [nTPM]":"6.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"124.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"55.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"106.8","Single Cell Type RNA - Endothelial cells [nTPM]":"123.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"163.6","Single Cell Type RNA - Erythroid cells [nTPM]":"25.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"68.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"78.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"53.7","Single Cell Type RNA - Fibroblasts [nTPM]":"43.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.1","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"168.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"255.2","Single Cell Type RNA - Hepatocytes [nTPM]":"246.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"100.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"97.3","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"49.0","Single Cell Type RNA - Langerhans cells [nTPM]":"31.1","Single Cell Type RNA - Late spermatids [nTPM]":"9.0","Single Cell Type RNA - Leydig cells [nTPM]":"96.3","Single Cell Type RNA - Macrophages [nTPM]":"35.0","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"62.8","Single Cell Type RNA - monocytes [nTPM]":"24.2","Single Cell Type RNA - Muller glia cells [nTPM]":"31.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"62.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"183.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"50.7","Single Cell Type RNA - Paneth cells [nTPM]":"68.8","Single Cell Type RNA - Peritubular cells [nTPM]":"245.3","Single Cell Type RNA - Plasma cells [nTPM]":"21.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"107.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"122.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"114.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"65.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.6","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"37.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5.2","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"68.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.3","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"81.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"65.2","Single Cell Type RNA - Urothelial cells [nTPM]":"130.0"},{"Gene":"ITPR3","Gene synonym":["IP3R3"],"Ensembl":"ENSG00000096433","Gene description":"Inositol 1,4,5-trisphosphate receptor type 3","Uniprot":["Q14573"],"Chromosome":"6","Position":"33620365-33696574","Protein class":["Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"123.0","Gastric mucus-secreting cells":"127.4","Late spermatids":"220.4","Pancreatic endocrine cells":"89.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"164.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003915","HPA064704"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA003915":"AB_1851845","HPA064704":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.3","Tissue RNA - adrenal gland [nTPM]":"11.4","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"6.1","Tissue RNA - breast [nTPM]":"14.6","Tissue RNA - cerebellum [nTPM]":"3.8","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"18.0","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"26.2","Tissue RNA - duodenum [nTPM]":"29.1","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"13.1","Tissue RNA - esophagus [nTPM]":"18.1","Tissue RNA - fallopian tube [nTPM]":"14.0","Tissue RNA - gallbladder [nTPM]":"15.3","Tissue RNA - heart muscle [nTPM]":"15.0","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"16.4","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"30.6","Tissue RNA - lymph node [nTPM]":"20.4","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"11.3","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"7.4","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"5.2","Tissue RNA - prostate [nTPM]":"13.9","Tissue RNA - rectum [nTPM]":"18.4","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"18.5","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"58.9","Tissue RNA - small intestine [nTPM]":"35.1","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"4.7","Tissue RNA - spleen [nTPM]":"39.8","Tissue RNA - stomach 1 [nTPM]":"41.5","Tissue RNA - testis [nTPM]":"15.4","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"14.3","Tissue RNA - thyroid gland [nTPM]":"54.0","Tissue RNA - tongue [nTPM]":"5.1","Tissue RNA - tonsil [nTPM]":"21.0","Tissue RNA - urinary bladder [nTPM]":"12.1","Tissue RNA - vagina [nTPM]":"24.0","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"73.7","Cell RNA - A549 [nTPM]":"34.0","Cell RNA - AF22 [nTPM]":"6.3","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"6.2","Cell RNA - ASC TERT1 [nTPM]":"19.3","Cell RNA - BEWO [nTPM]":"40.9","Cell RNA - BJ [nTPM]":"24.8","Cell RNA - BJ hTERT+ [nTPM]":"62.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.4","Cell RNA - CACO-2 [nTPM]":"46.7","Cell RNA - CAPAN-2 [nTPM]":"55.9","Cell RNA - Daudi [nTPM]":"62.6","Cell RNA - EFO-21 [nTPM]":"26.1","Cell RNA - fHDF\/TERT166 [nTPM]":"17.9","Cell RNA - GAMG [nTPM]":"76.1","Cell RNA - HaCaT [nTPM]":"70.9","Cell RNA - HAP1 [nTPM]":"28.6","Cell RNA - HBEC3-KT [nTPM]":"66.7","Cell RNA - HBF TERT88 [nTPM]":"15.7","Cell RNA - HDLM-2 [nTPM]":"36.8","Cell RNA - HEK 293 [nTPM]":"24.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"102.6","Cell RNA - Hep G2 [nTPM]":"52.0","Cell RNA - HHSteC [nTPM]":"14.1","Cell RNA - HL-60 [nTPM]":"11.3","Cell RNA - HMC-1 [nTPM]":"7.9","Cell RNA - HSkMC [nTPM]":"14.0","Cell RNA - hTCEpi [nTPM]":"59.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"76.7","Cell RNA - hTERT-HME1 [nTPM]":"164.7","Cell RNA - hTERT-RPE1 [nTPM]":"66.5","Cell RNA - HUVEC TERT2 [nTPM]":"52.1","Cell RNA - JURKAT [nTPM]":"24.5","Cell RNA - K-562 [nTPM]":"25.0","Cell RNA - Karpas-707 [nTPM]":"19.7","Cell RNA - LHCN-M2 [nTPM]":"33.3","Cell RNA - MCF7 [nTPM]":"35.0","Cell RNA - MOLT-4 [nTPM]":"19.0","Cell RNA - NB-4 [nTPM]":"6.4","Cell RNA - NTERA-2 [nTPM]":"6.2","Cell RNA - OE19 [nTPM]":"55.8","Cell RNA - PC-3 [nTPM]":"49.4","Cell RNA - REH [nTPM]":"29.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"37.1","Cell RNA - RPTEC TERT1 [nTPM]":"107.6","Cell RNA - RT4 [nTPM]":"50.9","Cell RNA - SCLC-21H [nTPM]":"57.3","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"42.8","Cell RNA - SK-BR-3 [nTPM]":"61.6","Cell RNA - SK-MEL-30 [nTPM]":"60.2","Cell RNA - SuSa [nTPM]":"6.9","Cell RNA - T-47d [nTPM]":"21.2","Cell RNA - THP-1 [nTPM]":"5.9","Cell RNA - TIME [nTPM]":"71.8","Cell RNA - U-138 MG [nTPM]":"41.1","Cell RNA - U-2 OS [nTPM]":"20.1","Cell RNA - U-2197 [nTPM]":"53.1","Cell RNA - U-251 MG [nTPM]":"55.2","Cell RNA - U-266\/70 [nTPM]":"13.5","Cell RNA - U-266\/84 [nTPM]":"14.3","Cell RNA - U-698 [nTPM]":"29.4","Cell RNA - U-87 MG [nTPM]":"32.8","Cell RNA - U-937 [nTPM]":"16.6","Cell RNA - WM-115 [nTPM]":"24.1","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"3.8","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"5.2","Brain RNA - spinal cord [nTPM]":"4.7","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"12.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"58.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"13.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"20.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"10.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"52.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"28.4","Single Cell Type RNA - Early spermatids [nTPM]":"123.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.9","Single Cell Type RNA - Erythroid cells [nTPM]":"6.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.3","Single Cell Type RNA - Fibroblasts [nTPM]":"9.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"127.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"43.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"6.9","Single Cell Type RNA - Late spermatids [nTPM]":"220.4","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"2.6","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"3.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"89.7","Single Cell Type RNA - Paneth cells [nTPM]":"41.6","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"18.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"3.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"13.1","Single Cell Type RNA - Theca cells [nTPM]":"5.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.6","Single Cell Type RNA - Urothelial cells [nTPM]":"20.7"},{"Gene":"JAZF1","Gene synonym":["DKFZp761K2222","TIP27","ZNF802"],"Ensembl":"ENSG00000153814","Gene description":"JAZF zinc finger 1","Uniprot":["Q86VZ6"],"Chromosome":"7","Position":"27830573-28180795","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"83.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"160.1","Excitatory neurons":"316.6","Inhibitory neurons":"306.3","Microglial cells":"168.6","Oligodendrocyte precursor cells":"241.3","Oligodendrocytes":"262.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"25.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"13.7","granulocytes":"25.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"53.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019271","HPA066967"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"CAB019271":null,"HPA066967":"AB_2685758"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.4","Tissue RNA - adrenal gland [nTPM]":"83.8","Tissue RNA - amygdala [nTPM]":"11.1","Tissue RNA - appendix [nTPM]":"10.9","Tissue RNA - basal ganglia [nTPM]":"12.4","Tissue RNA - bone marrow [nTPM]":"24.4","Tissue RNA - breast [nTPM]":"11.7","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"16.5","Tissue RNA - cervix [nTPM]":"62.4","Tissue RNA - choroid plexus [nTPM]":"12.4","Tissue RNA - colon [nTPM]":"32.8","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"41.8","Tissue RNA - epididymis [nTPM]":"21.3","Tissue RNA - esophagus [nTPM]":"10.1","Tissue RNA - fallopian tube [nTPM]":"16.4","Tissue RNA - gallbladder [nTPM]":"12.4","Tissue RNA - heart muscle [nTPM]":"22.4","Tissue RNA - hippocampal formation [nTPM]":"13.2","Tissue RNA - hypothalamus [nTPM]":"15.3","Tissue RNA - kidney [nTPM]":"5.1","Tissue RNA - liver [nTPM]":"15.7","Tissue RNA - lung [nTPM]":"10.1","Tissue RNA - lymph node [nTPM]":"14.6","Tissue RNA - medulla oblongata [nTPM]":"7.3","Tissue RNA - midbrain [nTPM]":"8.3","Tissue RNA - ovary [nTPM]":"13.9","Tissue RNA - pancreas [nTPM]":"6.6","Tissue RNA - parathyroid gland [nTPM]":"6.3","Tissue RNA - pituitary gland [nTPM]":"13.4","Tissue RNA - placenta [nTPM]":"16.1","Tissue RNA - pons [nTPM]":"9.1","Tissue RNA - prostate [nTPM]":"29.5","Tissue RNA - rectum [nTPM]":"8.3","Tissue RNA - retina [nTPM]":"7.8","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"35.2","Tissue RNA - skeletal muscle [nTPM]":"6.9","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"38.6","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"14.6","Tissue RNA - stomach 1 [nTPM]":"8.3","Tissue RNA - testis [nTPM]":"18.8","Tissue RNA - thalamus [nTPM]":"17.4","Tissue RNA - thymus [nTPM]":"11.5","Tissue RNA - thyroid gland [nTPM]":"14.9","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"15.9","Tissue RNA - urinary bladder [nTPM]":"19.2","Tissue RNA - vagina [nTPM]":"27.3","Tissue RNA - white matter [nTPM]":"10.0","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"1.0","Cell RNA - ASC diff [nTPM]":"35.6","Cell RNA - ASC TERT1 [nTPM]":"42.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"11.1","Cell RNA - BJ hTERT+ [nTPM]":"28.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.8","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"7.6","Cell RNA - Daudi [nTPM]":"33.7","Cell RNA - EFO-21 [nTPM]":"22.6","Cell RNA - fHDF\/TERT166 [nTPM]":"23.5","Cell RNA - GAMG [nTPM]":"12.5","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"6.3","Cell RNA - HBEC3-KT [nTPM]":"8.5","Cell RNA - HBF TERT88 [nTPM]":"15.0","Cell RNA - HDLM-2 [nTPM]":"5.1","Cell RNA - HEK 293 [nTPM]":"10.2","Cell RNA - HEL [nTPM]":"12.2","Cell RNA - HeLa [nTPM]":"7.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"24.2","Cell RNA - HL-60 [nTPM]":"4.8","Cell RNA - HMC-1 [nTPM]":"3.1","Cell RNA - HSkMC [nTPM]":"19.4","Cell RNA - hTCEpi [nTPM]":"10.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.8","Cell RNA - hTERT-HME1 [nTPM]":"8.9","Cell RNA - hTERT-RPE1 [nTPM]":"14.1","Cell RNA - HUVEC TERT2 [nTPM]":"11.8","Cell RNA - JURKAT [nTPM]":"2.2","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"53.2","Cell RNA - LHCN-M2 [nTPM]":"10.3","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"1.3","Cell RNA - NB-4 [nTPM]":"17.5","Cell RNA - NTERA-2 [nTPM]":"10.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"3.6","Cell RNA - RH-30 [nTPM]":"2.2","Cell RNA - RPMI-8226 [nTPM]":"10.1","Cell RNA - RPTEC TERT1 [nTPM]":"6.7","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"3.0","Cell RNA - SH-SY5Y [nTPM]":"4.7","Cell RNA - SiHa [nTPM]":"9.2","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"12.0","Cell RNA - SuSa [nTPM]":"14.0","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"6.1","Cell RNA - TIME [nTPM]":"11.7","Cell RNA - U-138 MG [nTPM]":"29.0","Cell RNA - U-2 OS [nTPM]":"11.0","Cell RNA - U-2197 [nTPM]":"8.0","Cell RNA - U-251 MG [nTPM]":"12.9","Cell RNA - U-266\/70 [nTPM]":"9.2","Cell RNA - U-266\/84 [nTPM]":"2.9","Cell RNA - U-698 [nTPM]":"12.5","Cell RNA - U-87 MG [nTPM]":"9.2","Cell RNA - U-937 [nTPM]":"12.5","Cell RNA - WM-115 [nTPM]":"16.2","Blood RNA - basophil [nTPM]":"25.6","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"6.9","Blood RNA - gdT-cell [nTPM]":"4.8","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"2.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.2","Blood RNA - myeloid DC [nTPM]":"3.7","Blood RNA - naive B-cell [nTPM]":"3.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"4.1","Blood RNA - non-classical monocyte [nTPM]":"3.5","Blood RNA - plasmacytoid DC [nTPM]":"13.7","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"11.1","Brain RNA - basal ganglia [nTPM]":"12.4","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"16.5","Brain RNA - hippocampal formation [nTPM]":"13.2","Brain RNA - hypothalamus [nTPM]":"15.3","Brain RNA - medulla oblongata [nTPM]":"7.3","Brain RNA - midbrain [nTPM]":"8.3","Brain RNA - pons [nTPM]":"9.1","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"17.4","Brain RNA - white matter [nTPM]":"10.0","Single Cell Type RNA - Adipocytes [nTPM]":"10.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.0","Single Cell Type RNA - Astrocytes [nTPM]":"57.8","Single Cell Type RNA - B-cells [nTPM]":"33.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"6.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"3.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"37.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.8","Single Cell Type RNA - Early spermatids [nTPM]":"122.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"160.1","Single Cell Type RNA - Endothelial cells [nTPM]":"14.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"115.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"316.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"24.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.6","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"12.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"5.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"306.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"25.7","Single Cell Type RNA - Langerhans cells [nTPM]":"45.6","Single Cell Type RNA - Late spermatids [nTPM]":"89.8","Single Cell Type RNA - Leydig cells [nTPM]":"55.0","Single Cell Type RNA - Macrophages [nTPM]":"28.0","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"168.6","Single Cell Type RNA - monocytes [nTPM]":"35.5","Single Cell Type RNA - Muller glia cells [nTPM]":"4.4","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"241.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"262.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"34.6","Single Cell Type RNA - Plasma cells [nTPM]":"8.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"16.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"25.3","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"KCNJ11","Gene synonym":["BIR","Kir6.2"],"Ensembl":"ENSG00000187486","Gene description":"Potassium inwardly rectifying channel subfamily J member 11","Uniprot":["Q14654"],"Chromosome":"11","Position":"17385248-17389331","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Diabetes mellitus","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skeletal muscle":"134.7","tongue":"40.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"14.1","Collecting duct cells":"5.5","Enteroendocrine cells":"4.2","Excitatory neurons":"5.5","Inhibitory neurons":"5.9","Oligodendrocyte precursor cells":"4.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"6.6","HEK 293":"12.3","MCF7":"10.0","SCLC-21H":"8.5","U-266\/84":"6.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048891"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048891":"AB_2680547"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.56e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.7","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"12.4","Tissue RNA - cerebral cortex [nTPM]":"11.9","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.9","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"1.5","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"13.8","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"4.2","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"2.5","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"11.3","Tissue RNA - parathyroid gland [nTPM]":"5.0","Tissue RNA - pituitary gland [nTPM]":"7.4","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"8.2","Tissue RNA - prostate [nTPM]":"2.2","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"134.7","Tissue RNA - skin 1 [nTPM]":"1.5","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"13.1","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"6.4","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"40.7","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"5.9","Cell RNA - A-431 [nTPM]":"1.5","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"4.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"2.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"6.6","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"4.1","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"1.6","Cell RNA - HEK 293 [nTPM]":"12.3","Cell RNA - HEL [nTPM]":"3.4","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"5.6","Cell RNA - K-562 [nTPM]":"3.5","Cell RNA - Karpas-707 [nTPM]":"3.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"10.0","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"1.1","Cell RNA - OE19 [nTPM]":"4.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"1.3","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"2.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"8.5","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"3.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"4.2","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"6.5","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"12.4","Brain RNA - cerebral cortex [nTPM]":"11.9","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"4.2","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"8.2","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"6.4","Brain RNA - white matter [nTPM]":"5.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"KCNQ1","Gene synonym":["JLNS1","KCNA8","KCNA9","Kv7.1","KVLQT1","LQT","LQT1"],"Ensembl":"ENSG00000053918","Gene description":"Potassium voltage-gated channel subfamily Q member 1","Uniprot":["P51787"],"Chromosome":"11","Position":"2444684-2849105","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Calmodulin-binding","Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Atrial fibrillation","Deafness","Diabetes mellitus","Disease variant","FDA approved drug targets","Long QT syndrome","Short QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"197.1","stomach 1":"98.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"47.6","Microglial cells":"71.2","Undifferentiated cells":"57.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"42.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"33.4","OE19":"41.4","RPMI-8226":"23.2","U-266\/70":"11.5","U-937":"13.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018656","HPA048553","HPA071107"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB018656":"AB_2131551","HPA048553":"AB_2680438","HPA071107":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.85e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.4","Tissue RNA - adrenal gland [nTPM]":"197.1","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"9.0","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"14.2","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"16.5","Tissue RNA - choroid plexus [nTPM]":"5.7","Tissue RNA - colon [nTPM]":"22.6","Tissue RNA - duodenum [nTPM]":"47.8","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"14.1","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"8.9","Tissue RNA - gallbladder [nTPM]":"19.5","Tissue RNA - heart muscle [nTPM]":"28.4","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"25.3","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"15.9","Tissue RNA - lymph node [nTPM]":"5.0","Tissue RNA - medulla oblongata [nTPM]":"4.1","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"1.4","Tissue RNA - pancreas [nTPM]":"61.2","Tissue RNA - parathyroid gland [nTPM]":"21.4","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"6.1","Tissue RNA - rectum [nTPM]":"15.2","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"20.0","Tissue RNA - seminal vesicle [nTPM]":"50.2","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"39.7","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"8.2","Tissue RNA - stomach 1 [nTPM]":"98.9","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"71.6","Tissue RNA - tongue [nTPM]":"1.6","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"14.7","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"5.8","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"1.9","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"1.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"3.7","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"33.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"41.4","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"23.2","Cell RNA - RPTEC TERT1 [nTPM]":"8.0","Cell RNA - RT4 [nTPM]":"2.7","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"5.6","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"10.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"11.5","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"13.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"3.1","Blood RNA - eosinophil [nTPM]":"3.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"3.8","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"2.8","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"4.1","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"7.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"8.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"7.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"23.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.9","Single Cell Type RNA - granulocytes [nTPM]":"19.7","Single Cell Type RNA - Granulosa cells [nTPM]":"47.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"1.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.1","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"25.4","Single Cell Type RNA - Langerhans cells [nTPM]":"15.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"19.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"71.2","Single Cell Type RNA - monocytes [nTPM]":"11.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"43.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.3","Single Cell Type RNA - Paneth cells [nTPM]":"20.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - T-cells [nTPM]":"4.0","Single Cell Type RNA - Theca cells [nTPM]":"16.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"57.8","Single Cell Type RNA - Urothelial cells [nTPM]":"20.4"},{"Gene":"KLF11","Gene synonym":["MODY7","TIEG2","Tieg3"],"Ensembl":"ENSG00000172059","Gene description":"Kruppel like factor 11","Uniprot":["O14901"],"Chromosome":"2","Position":"10042849-10054836","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Apoptosis","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"135.0","Suprabasal keratinocytes":"86.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"47.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058276"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Focal adhesion sites","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Focal adhesion sites","Cytosol"],"Antibody RRID":{"HPA058276":"AB_2683664"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.7","Tissue RNA - adrenal gland [nTPM]":"15.6","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"27.8","Tissue RNA - breast [nTPM]":"22.3","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"13.5","Tissue RNA - choroid plexus [nTPM]":"4.1","Tissue RNA - colon [nTPM]":"17.9","Tissue RNA - duodenum [nTPM]":"7.5","Tissue RNA - endometrium 1 [nTPM]":"20.0","Tissue RNA - epididymis [nTPM]":"9.7","Tissue RNA - esophagus [nTPM]":"13.2","Tissue RNA - fallopian tube [nTPM]":"13.7","Tissue RNA - gallbladder [nTPM]":"18.1","Tissue RNA - heart muscle [nTPM]":"19.1","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"15.7","Tissue RNA - liver [nTPM]":"35.2","Tissue RNA - lung [nTPM]":"22.4","Tissue RNA - lymph node [nTPM]":"9.3","Tissue RNA - medulla oblongata [nTPM]":"3.7","Tissue RNA - midbrain [nTPM]":"3.3","Tissue RNA - ovary [nTPM]":"23.9","Tissue RNA - pancreas [nTPM]":"54.2","Tissue RNA - parathyroid gland [nTPM]":"18.3","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"19.5","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"10.1","Tissue RNA - rectum [nTPM]":"9.3","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"15.9","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"12.1","Tissue RNA - skin 1 [nTPM]":"26.9","Tissue RNA - small intestine [nTPM]":"8.7","Tissue RNA - smooth muscle [nTPM]":"16.8","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"18.8","Tissue RNA - stomach 1 [nTPM]":"12.4","Tissue RNA - testis [nTPM]":"30.0","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"16.5","Tissue RNA - tongue [nTPM]":"27.3","Tissue RNA - tonsil [nTPM]":"5.5","Tissue RNA - urinary bladder [nTPM]":"12.6","Tissue RNA - vagina [nTPM]":"13.1","Tissue RNA - white matter [nTPM]":"5.1","Cell RNA - A-431 [nTPM]":"6.9","Cell RNA - A549 [nTPM]":"3.3","Cell RNA - AF22 [nTPM]":"7.8","Cell RNA - AN3-CA [nTPM]":"0.7","Cell RNA - ASC diff [nTPM]":"5.3","Cell RNA - ASC TERT1 [nTPM]":"9.4","Cell RNA - BEWO [nTPM]":"18.8","Cell RNA - BJ [nTPM]":"7.9","Cell RNA - BJ hTERT+ [nTPM]":"7.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.6","Cell RNA - CACO-2 [nTPM]":"7.8","Cell RNA - CAPAN-2 [nTPM]":"15.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"13.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.6","Cell RNA - GAMG [nTPM]":"17.9","Cell RNA - HaCaT [nTPM]":"1.6","Cell RNA - HAP1 [nTPM]":"6.8","Cell RNA - HBEC3-KT [nTPM]":"6.1","Cell RNA - HBF TERT88 [nTPM]":"2.9","Cell RNA - HDLM-2 [nTPM]":"47.6","Cell RNA - HEK 293 [nTPM]":"5.2","Cell RNA - HEL [nTPM]":"3.5","Cell RNA - HeLa [nTPM]":"9.7","Cell RNA - Hep G2 [nTPM]":"1.6","Cell RNA - HHSteC [nTPM]":"5.2","Cell RNA - HL-60 [nTPM]":"14.6","Cell RNA - HMC-1 [nTPM]":"22.1","Cell RNA - HSkMC [nTPM]":"14.7","Cell RNA - hTCEpi [nTPM]":"22.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.4","Cell RNA - hTERT-HME1 [nTPM]":"2.3","Cell RNA - hTERT-RPE1 [nTPM]":"11.4","Cell RNA - HUVEC TERT2 [nTPM]":"3.9","Cell RNA - JURKAT [nTPM]":"1.3","Cell RNA - K-562 [nTPM]":"9.7","Cell RNA - Karpas-707 [nTPM]":"30.8","Cell RNA - LHCN-M2 [nTPM]":"4.6","Cell RNA - MCF7 [nTPM]":"8.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"2.7","Cell RNA - NTERA-2 [nTPM]":"12.5","Cell RNA - OE19 [nTPM]":"5.6","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"7.8","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"13.6","Cell RNA - RPTEC TERT1 [nTPM]":"10.8","Cell RNA - RT4 [nTPM]":"8.5","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"6.2","Cell RNA - SiHa [nTPM]":"12.0","Cell RNA - SK-BR-3 [nTPM]":"24.5","Cell RNA - SK-MEL-30 [nTPM]":"23.4","Cell RNA - SuSa [nTPM]":"12.2","Cell RNA - T-47d [nTPM]":"5.7","Cell RNA - THP-1 [nTPM]":"19.6","Cell RNA - TIME [nTPM]":"11.2","Cell RNA - U-138 MG [nTPM]":"19.3","Cell RNA - U-2 OS [nTPM]":"15.9","Cell RNA - U-2197 [nTPM]":"14.7","Cell RNA - U-251 MG [nTPM]":"2.6","Cell RNA - U-266\/70 [nTPM]":"27.9","Cell RNA - U-266\/84 [nTPM]":"36.0","Cell RNA - U-698 [nTPM]":"18.7","Cell RNA - U-87 MG [nTPM]":"5.0","Cell RNA - U-937 [nTPM]":"3.8","Cell RNA - WM-115 [nTPM]":"10.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"8.2","Blood RNA - eosinophil [nTPM]":"2.0","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"12.3","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"3.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"7.3","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"6.6","Blood RNA - non-classical monocyte [nTPM]":"14.8","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"3.0","Blood RNA - total PBMC [nTPM]":"5.4","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"3.7","Brain RNA - midbrain [nTPM]":"3.3","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"5.1","Single Cell Type RNA - Adipocytes [nTPM]":"58.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"12.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"60.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.2","Single Cell Type RNA - dendritic cells [nTPM]":"10.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"8.2","Single Cell Type RNA - Early spermatids [nTPM]":"135.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.5","Single Cell Type RNA - Endothelial cells [nTPM]":"33.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.1","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.2","Single Cell Type RNA - Fibroblasts [nTPM]":"17.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.6","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"15.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.5","Single Cell Type RNA - Hepatocytes [nTPM]":"38.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.5","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"32.4","Single Cell Type RNA - Langerhans cells [nTPM]":"42.4","Single Cell Type RNA - Late spermatids [nTPM]":"25.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"22.0","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"16.6","Single Cell Type RNA - Muller glia cells [nTPM]":"2.2","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"1.5","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"5.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.7","Single Cell Type RNA - Spermatocytes [nTPM]":"13.8","Single Cell Type RNA - Spermatogonia [nTPM]":"39.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"86.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - T-cells [nTPM]":"10.8","Single Cell Type RNA - Theca cells [nTPM]":"11.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.8","Single Cell Type RNA - Urothelial cells [nTPM]":"11.7"},{"Gene":"MTNR1B","Gene synonym":[],"Ensembl":"ENSG00000134640","Gene description":"Melatonin receptor 1B","Uniprot":["P49286"],"Chromosome":"11","Position":"92969651-92985066","Protein class":["FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"3.1","placenta":"1.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"GAMG":"4.9","SuSa":"1.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074024"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074024":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"3.0","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"4.9","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"3.0","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NAA25","Gene synonym":["C12orf30","FLJ13089"],"Ensembl":"ENSG00000111300","Gene description":"N-alpha-acetyltransferase 25, NatB auxiliary subunit","Uniprot":["Q14CX7"],"Chromosome":"12","Position":"112026689-112108796","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"146.0","Oligodendrocytes":"109.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039322"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039322":"AB_10697548"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.53e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.5","Tissue RNA - adrenal gland [nTPM]":"6.1","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"9.8","Tissue RNA - breast [nTPM]":"6.8","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"8.1","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"8.5","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"5.5","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"5.6","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"6.6","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"7.0","Tissue RNA - pancreas [nTPM]":"6.9","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"7.7","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"4.2","Tissue RNA - retina [nTPM]":"14.8","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"4.4","Tissue RNA - skeletal muscle [nTPM]":"14.9","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"4.8","Tissue RNA - smooth muscle [nTPM]":"5.4","Tissue RNA - spinal cord [nTPM]":"3.6","Tissue RNA - spleen [nTPM]":"5.3","Tissue RNA - stomach 1 [nTPM]":"4.9","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"6.0","Tissue RNA - thyroid gland [nTPM]":"5.7","Tissue RNA - tongue [nTPM]":"9.9","Tissue RNA - tonsil [nTPM]":"6.9","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"6.7","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"16.7","Cell RNA - A549 [nTPM]":"16.1","Cell RNA - AF22 [nTPM]":"14.8","Cell RNA - AN3-CA [nTPM]":"11.9","Cell RNA - ASC diff [nTPM]":"8.1","Cell RNA - ASC TERT1 [nTPM]":"14.0","Cell RNA - BEWO [nTPM]":"17.9","Cell RNA - BJ [nTPM]":"15.3","Cell RNA - BJ hTERT+ [nTPM]":"12.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.4","Cell RNA - CACO-2 [nTPM]":"16.2","Cell RNA - CAPAN-2 [nTPM]":"8.6","Cell RNA - Daudi [nTPM]":"28.9","Cell RNA - EFO-21 [nTPM]":"14.4","Cell RNA - fHDF\/TERT166 [nTPM]":"12.3","Cell RNA - GAMG [nTPM]":"10.5","Cell RNA - HaCaT [nTPM]":"19.2","Cell RNA - HAP1 [nTPM]":"32.8","Cell RNA - HBEC3-KT [nTPM]":"13.0","Cell RNA - HBF TERT88 [nTPM]":"25.1","Cell RNA - HDLM-2 [nTPM]":"16.6","Cell RNA - HEK 293 [nTPM]":"22.9","Cell RNA - HEL [nTPM]":"23.6","Cell RNA - HeLa [nTPM]":"15.9","Cell RNA - Hep G2 [nTPM]":"15.0","Cell RNA - HHSteC [nTPM]":"13.2","Cell RNA - HL-60 [nTPM]":"34.0","Cell RNA - HMC-1 [nTPM]":"13.7","Cell RNA - HSkMC [nTPM]":"12.1","Cell RNA - hTCEpi [nTPM]":"15.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.3","Cell RNA - hTERT-HME1 [nTPM]":"21.8","Cell RNA - hTERT-RPE1 [nTPM]":"15.5","Cell RNA - HUVEC TERT2 [nTPM]":"16.1","Cell RNA - JURKAT [nTPM]":"12.6","Cell RNA - K-562 [nTPM]":"35.3","Cell RNA - Karpas-707 [nTPM]":"3.7","Cell RNA - LHCN-M2 [nTPM]":"16.7","Cell RNA - MCF7 [nTPM]":"13.5","Cell RNA - MOLT-4 [nTPM]":"19.6","Cell RNA - NB-4 [nTPM]":"24.9","Cell RNA - NTERA-2 [nTPM]":"22.1","Cell RNA - OE19 [nTPM]":"34.2","Cell RNA - PC-3 [nTPM]":"18.6","Cell RNA - REH [nTPM]":"21.5","Cell RNA - RH-30 [nTPM]":"15.2","Cell RNA - RPMI-8226 [nTPM]":"19.7","Cell RNA - RPTEC TERT1 [nTPM]":"14.0","Cell RNA - RT4 [nTPM]":"27.0","Cell RNA - SCLC-21H [nTPM]":"19.1","Cell RNA - SH-SY5Y [nTPM]":"10.5","Cell RNA - SiHa [nTPM]":"16.9","Cell RNA - SK-BR-3 [nTPM]":"19.8","Cell RNA - SK-MEL-30 [nTPM]":"15.0","Cell RNA - SuSa [nTPM]":"14.0","Cell RNA - T-47d [nTPM]":"19.3","Cell RNA - THP-1 [nTPM]":"13.4","Cell RNA - TIME [nTPM]":"13.7","Cell RNA - U-138 MG [nTPM]":"15.2","Cell RNA - U-2 OS [nTPM]":"13.6","Cell RNA - U-2197 [nTPM]":"17.0","Cell RNA - U-251 MG [nTPM]":"21.3","Cell RNA - U-266\/70 [nTPM]":"15.0","Cell RNA - U-266\/84 [nTPM]":"30.4","Cell RNA - U-698 [nTPM]":"33.0","Cell RNA - U-87 MG [nTPM]":"19.4","Cell RNA - U-937 [nTPM]":"14.7","Cell RNA - WM-115 [nTPM]":"15.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"2.3","Blood RNA - myeloid DC [nTPM]":"3.5","Blood RNA - naive B-cell [nTPM]":"2.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.2","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"3.7","Blood RNA - T-reg [nTPM]":"2.5","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"8.1","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"7.7","Brain RNA - spinal cord [nTPM]":"3.6","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"16.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.2","Single Cell Type RNA - Astrocytes [nTPM]":"44.1","Single Cell Type RNA - B-cells [nTPM]":"23.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"66.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"38.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"26.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"146.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.6","Single Cell Type RNA - dendritic cells [nTPM]":"20.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.3","Single Cell Type RNA - Early spermatids [nTPM]":"26.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.9","Single Cell Type RNA - Endothelial cells [nTPM]":"17.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"17.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"71.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.6","Single Cell Type RNA - Fibroblasts [nTPM]":"17.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.8","Single Cell Type RNA - granulocytes [nTPM]":"20.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"19.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.0","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"68.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.9","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"15.4","Single Cell Type RNA - Langerhans cells [nTPM]":"25.2","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"16.5","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"83.8","Single Cell Type RNA - Muller glia cells [nTPM]":"13.0","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"109.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.4","Single Cell Type RNA - Paneth cells [nTPM]":"7.5","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"15.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"61.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"67.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.7","Single Cell Type RNA - Spermatocytes [nTPM]":"31.5","Single Cell Type RNA - Spermatogonia [nTPM]":"29.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"70.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.6","Single Cell Type RNA - T-cells [nTPM]":"15.3","Single Cell Type RNA - Theca cells [nTPM]":"20.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.7","Single Cell Type RNA - Urothelial cells [nTPM]":"48.1"},{"Gene":"NEUROD1","Gene synonym":["BETA2","BHF-1","bHLHa3","MODY6","NEUROD"],"Ensembl":"ENSG00000162992","Gene description":"Neuronal differentiation 1","Uniprot":["Q13562"],"Chromosome":"2","Position":"181673088-181680547","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"61.4","retina":"125.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"77.5","Cone photoreceptor cells":"150.1","Enteroendocrine cells":"424.2","Rod photoreceptor cells":"203.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"1.9","pancreatic cancer":"4.3"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"cerebellum":"61.4"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"74","RNA cell line specific nTPM":{"SCLC-21H":"321.5"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"14","RNA mouse brain regional specific nTPM":{"cerebellum":"216.2"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"19","RNA pig brain regional specific nTPM":{"cerebellum":"217.0"},"Antibody":["HPA003278","CAB022450"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 17: Intestinal endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022450":null,"HPA003278":"AB_1845331"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.34e-4"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"61.4","Tissue RNA - cerebral cortex [nTPM]":"7.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"9.2","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"2.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"10.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"5.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"125.7","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"5.4","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"321.5","Cell RNA - SH-SY5Y [nTPM]":"4.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"61.4","Brain RNA - cerebral cortex [nTPM]":"7.2","Brain RNA - hippocampal formation [nTPM]":"9.2","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"2.4","Brain RNA - pons [nTPM]":"5.2","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"77.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"150.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"424.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"25.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"12.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"203.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"NOTCH2","Gene synonym":[],"Ensembl":"ENSG00000134250","Gene description":"Notch receptor 2","Uniprot":["Q04721"],"Chromosome":"1","Position":"119911553-120100779","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Notch signaling pathway","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048743"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA048743":"AB_2680508"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.24e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.48e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-3"},"Tissue RNA - adipose tissue [nTPM]":"27.1","Tissue RNA - adrenal gland [nTPM]":"12.9","Tissue RNA - amygdala [nTPM]":"16.4","Tissue RNA - appendix [nTPM]":"20.4","Tissue RNA - basal ganglia [nTPM]":"13.6","Tissue RNA - bone marrow [nTPM]":"13.7","Tissue RNA - breast [nTPM]":"24.8","Tissue RNA - cerebellum [nTPM]":"11.9","Tissue RNA - cerebral cortex [nTPM]":"16.4","Tissue RNA - cervix [nTPM]":"31.0","Tissue RNA - choroid plexus [nTPM]":"20.3","Tissue RNA - colon [nTPM]":"16.0","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"21.2","Tissue RNA - epididymis [nTPM]":"20.8","Tissue RNA - esophagus [nTPM]":"24.9","Tissue RNA - fallopian tube [nTPM]":"25.7","Tissue RNA - gallbladder [nTPM]":"18.5","Tissue RNA - heart muscle [nTPM]":"14.2","Tissue RNA - hippocampal formation [nTPM]":"15.9","Tissue RNA - hypothalamus [nTPM]":"13.7","Tissue RNA - kidney [nTPM]":"10.9","Tissue RNA - liver [nTPM]":"19.6","Tissue RNA - lung [nTPM]":"20.2","Tissue RNA - lymph node [nTPM]":"16.7","Tissue RNA - medulla oblongata [nTPM]":"20.6","Tissue RNA - midbrain [nTPM]":"18.6","Tissue RNA - ovary [nTPM]":"33.9","Tissue RNA - pancreas [nTPM]":"20.1","Tissue RNA - parathyroid gland [nTPM]":"12.1","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"24.9","Tissue RNA - pons [nTPM]":"13.9","Tissue RNA - prostate [nTPM]":"20.4","Tissue RNA - rectum [nTPM]":"13.6","Tissue RNA - retina [nTPM]":"19.3","Tissue RNA - salivary gland [nTPM]":"17.1","Tissue RNA - seminal vesicle [nTPM]":"22.2","Tissue RNA - skeletal muscle [nTPM]":"6.4","Tissue RNA - skin 1 [nTPM]":"32.3","Tissue RNA - small intestine [nTPM]":"11.9","Tissue RNA - smooth muscle [nTPM]":"26.6","Tissue RNA - spinal cord [nTPM]":"15.7","Tissue RNA - spleen [nTPM]":"25.3","Tissue RNA - stomach 1 [nTPM]":"10.5","Tissue RNA - testis [nTPM]":"25.4","Tissue RNA - thalamus [nTPM]":"19.3","Tissue RNA - thymus [nTPM]":"15.3","Tissue RNA - thyroid gland [nTPM]":"21.2","Tissue RNA - tongue [nTPM]":"8.9","Tissue RNA - tonsil [nTPM]":"17.9","Tissue RNA - urinary bladder [nTPM]":"19.0","Tissue RNA - vagina [nTPM]":"24.1","Tissue RNA - white matter [nTPM]":"14.8","Cell RNA - A-431 [nTPM]":"54.2","Cell RNA - A549 [nTPM]":"17.7","Cell RNA - AF22 [nTPM]":"27.0","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"108.5","Cell RNA - ASC TERT1 [nTPM]":"92.7","Cell RNA - BEWO [nTPM]":"26.6","Cell RNA - BJ [nTPM]":"39.7","Cell RNA - BJ hTERT+ [nTPM]":"54.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"51.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.8","Cell RNA - CACO-2 [nTPM]":"16.3","Cell RNA - CAPAN-2 [nTPM]":"14.2","Cell RNA - Daudi [nTPM]":"1.4","Cell RNA - EFO-21 [nTPM]":"32.6","Cell RNA - fHDF\/TERT166 [nTPM]":"75.3","Cell RNA - GAMG [nTPM]":"46.2","Cell RNA - HaCaT [nTPM]":"20.1","Cell RNA - HAP1 [nTPM]":"42.8","Cell RNA - HBEC3-KT [nTPM]":"35.3","Cell RNA - HBF TERT88 [nTPM]":"82.5","Cell RNA - HDLM-2 [nTPM]":"64.0","Cell RNA - HEK 293 [nTPM]":"27.2","Cell RNA - HEL [nTPM]":"32.1","Cell RNA - HeLa [nTPM]":"45.7","Cell RNA - Hep G2 [nTPM]":"1.6","Cell RNA - HHSteC [nTPM]":"40.5","Cell RNA - HL-60 [nTPM]":"32.7","Cell RNA - HMC-1 [nTPM]":"8.0","Cell RNA - HSkMC [nTPM]":"75.5","Cell RNA - hTCEpi [nTPM]":"22.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"155.2","Cell RNA - hTERT-HME1 [nTPM]":"103.7","Cell RNA - hTERT-RPE1 [nTPM]":"78.4","Cell RNA - HUVEC TERT2 [nTPM]":"26.9","Cell RNA - JURKAT [nTPM]":"14.5","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"65.3","Cell RNA - LHCN-M2 [nTPM]":"63.7","Cell RNA - MCF7 [nTPM]":"59.2","Cell RNA - MOLT-4 [nTPM]":"13.9","Cell RNA - NB-4 [nTPM]":"9.2","Cell RNA - NTERA-2 [nTPM]":"34.6","Cell RNA - OE19 [nTPM]":"5.0","Cell RNA - PC-3 [nTPM]":"19.6","Cell RNA - REH [nTPM]":"9.1","Cell RNA - RH-30 [nTPM]":"94.2","Cell RNA - RPMI-8226 [nTPM]":"36.1","Cell RNA - RPTEC TERT1 [nTPM]":"27.3","Cell RNA - RT4 [nTPM]":"33.4","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"13.4","Cell RNA - SiHa [nTPM]":"54.5","Cell RNA - SK-BR-3 [nTPM]":"50.0","Cell RNA - SK-MEL-30 [nTPM]":"27.9","Cell RNA - SuSa [nTPM]":"53.4","Cell RNA - T-47d [nTPM]":"28.0","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"97.0","Cell RNA - U-138 MG [nTPM]":"67.0","Cell RNA - U-2 OS [nTPM]":"45.8","Cell RNA - U-2197 [nTPM]":"102.7","Cell RNA - U-251 MG [nTPM]":"63.1","Cell RNA - U-266\/70 [nTPM]":"27.9","Cell RNA - U-266\/84 [nTPM]":"16.8","Cell RNA - U-698 [nTPM]":"16.5","Cell RNA - U-87 MG [nTPM]":"98.7","Cell RNA - U-937 [nTPM]":"29.5","Cell RNA - WM-115 [nTPM]":"65.2","Blood RNA - basophil [nTPM]":"15.0","Blood RNA - classical monocyte [nTPM]":"14.9","Blood RNA - eosinophil [nTPM]":"22.9","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"7.3","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"39.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"23.7","Blood RNA - naive B-cell [nTPM]":"33.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"8.9","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"10.5","Blood RNA - plasmacytoid DC [nTPM]":"12.3","Blood RNA - T-reg [nTPM]":"3.8","Blood RNA - total PBMC [nTPM]":"4.4","Brain RNA - amygdala [nTPM]":"16.4","Brain RNA - basal ganglia [nTPM]":"13.6","Brain RNA - cerebellum [nTPM]":"11.9","Brain RNA - cerebral cortex [nTPM]":"16.4","Brain RNA - hippocampal formation [nTPM]":"15.9","Brain RNA - hypothalamus [nTPM]":"13.7","Brain RNA - medulla oblongata [nTPM]":"20.6","Brain RNA - midbrain [nTPM]":"18.6","Brain RNA - pons [nTPM]":"13.9","Brain RNA - spinal cord [nTPM]":"15.7","Brain RNA - thalamus [nTPM]":"19.3","Brain RNA - white matter [nTPM]":"14.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.5","Single Cell Type RNA - Astrocytes [nTPM]":"125.4","Single Cell Type RNA - B-cells [nTPM]":"36.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"56.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"3.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"28.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - dendritic cells [nTPM]":"26.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"46.8","Single Cell Type RNA - Early spermatids [nTPM]":"17.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.9","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"18.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.9","Single Cell Type RNA - Fibroblasts [nTPM]":"67.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.1","Single Cell Type RNA - granulocytes [nTPM]":"15.8","Single Cell Type RNA - Granulosa cells [nTPM]":"78.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"41.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.7","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"74.7","Single Cell Type RNA - Langerhans cells [nTPM]":"78.2","Single Cell Type RNA - Late spermatids [nTPM]":"12.6","Single Cell Type RNA - Leydig cells [nTPM]":"55.0","Single Cell Type RNA - Macrophages [nTPM]":"76.6","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"43.1","Single Cell Type RNA - monocytes [nTPM]":"79.3","Single Cell Type RNA - Muller glia cells [nTPM]":"46.2","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"75.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.8","Single Cell Type RNA - Paneth cells [nTPM]":"105.5","Single Cell Type RNA - Peritubular cells [nTPM]":"85.4","Single Cell Type RNA - Plasma cells [nTPM]":"14.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"83.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.0","Single Cell Type RNA - Spermatocytes [nTPM]":"10.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"75.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"88.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"18.5","Single Cell Type RNA - Theca cells [nTPM]":"22.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.8","Single Cell Type RNA - Urothelial cells [nTPM]":"66.9"},{"Gene":"PAX4","Gene synonym":["MODY9"],"Ensembl":"ENSG00000106331","Gene description":"Paired box 4","Uniprot":["O43316"],"Chromosome":"7","Position":"127610292-127618142","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"1.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Enteroendocrine cells":"85.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"49","RNA cell line specific nTPM":{"SCLC-21H":"10.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 17: Intestinal endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"10.6","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"85.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"11.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PDX1","Gene synonym":["IDX-1","IPF1","MODY4","PDX-1","STF-1"],"Ensembl":"ENSG00000139515","Gene description":"Pancreatic and duodenal homeobox 1","Uniprot":["P52945"],"Chromosome":"13","Position":"27920000-27926313","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"41.8","pancreas":"13.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"15.7","Ductal cells":"13.3","Enteroendocrine cells":"13.8","Exocrine glandular cells":"9.8","Gastric mucus-secreting cells":"4.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"8.4","pancreatic cancer":"8.6","stomach cancer":"7.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"4.0","HEK 293":"2.3","HeLa":"5.9","OE19":"6.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025873","HPA059146"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB025873":null,"HPA059146":"AB_2683927"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"41.8","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"13.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"5.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"1.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"1.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"4.0","Cell RNA - HEK 293 [nTPM]":"2.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"5.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"6.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"13.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PLAGL1","Gene synonym":["LOT1","ZAC"],"Ensembl":"ENSG00000118495","Gene description":"PLAG1 like zinc finger 1","Uniprot":["Q9UM63"],"Chromosome":"6","Position":"143940300-144064599","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"252.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"143.6","Leydig cells":"138.5","Theca cells":"205.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"99.0","RH-30":"94.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055706"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"HPA055706":"AB_2682893"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.94e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.61e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-3"},"Tissue RNA - adipose tissue [nTPM]":"37.7","Tissue RNA - adrenal gland [nTPM]":"74.8","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"18.5","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"21.7","Tissue RNA - breast [nTPM]":"29.6","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"7.0","Tissue RNA - cervix [nTPM]":"31.4","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"28.8","Tissue RNA - duodenum [nTPM]":"9.6","Tissue RNA - endometrium 1 [nTPM]":"29.5","Tissue RNA - epididymis [nTPM]":"9.0","Tissue RNA - esophagus [nTPM]":"32.9","Tissue RNA - fallopian tube [nTPM]":"20.8","Tissue RNA - gallbladder [nTPM]":"26.9","Tissue RNA - heart muscle [nTPM]":"26.4","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"17.0","Tissue RNA - liver [nTPM]":"3.6","Tissue RNA - lung [nTPM]":"26.7","Tissue RNA - lymph node [nTPM]":"12.1","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"4.1","Tissue RNA - ovary [nTPM]":"36.5","Tissue RNA - pancreas [nTPM]":"27.7","Tissue RNA - parathyroid gland [nTPM]":"9.5","Tissue RNA - pituitary gland [nTPM]":"81.6","Tissue RNA - placenta [nTPM]":"252.3","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"26.0","Tissue RNA - rectum [nTPM]":"21.3","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"30.1","Tissue RNA - seminal vesicle [nTPM]":"12.1","Tissue RNA - skeletal muscle [nTPM]":"12.2","Tissue RNA - skin 1 [nTPM]":"61.9","Tissue RNA - small intestine [nTPM]":"20.6","Tissue RNA - smooth muscle [nTPM]":"19.7","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"15.6","Tissue RNA - stomach 1 [nTPM]":"26.9","Tissue RNA - testis [nTPM]":"8.7","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"6.6","Tissue RNA - thyroid gland [nTPM]":"13.8","Tissue RNA - tongue [nTPM]":"22.3","Tissue RNA - tonsil [nTPM]":"12.1","Tissue RNA - urinary bladder [nTPM]":"39.6","Tissue RNA - vagina [nTPM]":"34.4","Tissue RNA - white matter [nTPM]":"4.0","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"5.0","Cell RNA - AF22 [nTPM]":"99.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"39.4","Cell RNA - ASC TERT1 [nTPM]":"78.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"32.9","Cell RNA - BJ hTERT+ [nTPM]":"21.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.5","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"6.0","Cell RNA - Daudi [nTPM]":"2.7","Cell RNA - EFO-21 [nTPM]":"16.0","Cell RNA - fHDF\/TERT166 [nTPM]":"30.4","Cell RNA - GAMG [nTPM]":"4.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"12.0","Cell RNA - HBF TERT88 [nTPM]":"32.2","Cell RNA - HDLM-2 [nTPM]":"3.1","Cell RNA - HEK 293 [nTPM]":"4.4","Cell RNA - HEL [nTPM]":"45.2","Cell RNA - HeLa [nTPM]":"58.7","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"13.9","Cell RNA - HL-60 [nTPM]":"40.9","Cell RNA - HMC-1 [nTPM]":"8.9","Cell RNA - HSkMC [nTPM]":"60.5","Cell RNA - hTCEpi [nTPM]":"4.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.8","Cell RNA - hTERT-HME1 [nTPM]":"13.8","Cell RNA - hTERT-RPE1 [nTPM]":"23.4","Cell RNA - HUVEC TERT2 [nTPM]":"33.5","Cell RNA - JURKAT [nTPM]":"16.1","Cell RNA - K-562 [nTPM]":"4.4","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"18.0","Cell RNA - MCF7 [nTPM]":"6.2","Cell RNA - MOLT-4 [nTPM]":"16.9","Cell RNA - NB-4 [nTPM]":"19.8","Cell RNA - NTERA-2 [nTPM]":"17.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"3.7","Cell RNA - REH [nTPM]":"20.7","Cell RNA - RH-30 [nTPM]":"94.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"33.1","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"8.7","Cell RNA - SH-SY5Y [nTPM]":"10.3","Cell RNA - SiHa [nTPM]":"51.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"29.6","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"50.1","Cell RNA - TIME [nTPM]":"19.8","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"35.2","Cell RNA - U-2197 [nTPM]":"77.7","Cell RNA - U-251 MG [nTPM]":"36.4","Cell RNA - U-266\/70 [nTPM]":"9.1","Cell RNA - U-266\/84 [nTPM]":"9.0","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"25.3","Cell RNA - U-937 [nTPM]":"16.6","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"4.9","Blood RNA - classical monocyte [nTPM]":"12.0","Blood RNA - eosinophil [nTPM]":"25.1","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"9.1","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"14.9","Blood RNA - naive B-cell [nTPM]":"5.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"21.7","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"6.7","Blood RNA - T-reg [nTPM]":"2.0","Blood RNA - total PBMC [nTPM]":"3.8","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"7.0","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"4.1","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"4.0","Single Cell Type RNA - Adipocytes [nTPM]":"19.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.0","Single Cell Type RNA - Astrocytes [nTPM]":"28.4","Single Cell Type RNA - B-cells [nTPM]":"15.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.6","Single Cell Type RNA - dendritic cells [nTPM]":"19.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"91.9","Single Cell Type RNA - Endothelial cells [nTPM]":"23.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.7","Single Cell Type RNA - Erythroid cells [nTPM]":"19.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"60.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.0","Single Cell Type RNA - Fibroblasts [nTPM]":"143.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.0","Single Cell Type RNA - granulocytes [nTPM]":"18.4","Single Cell Type RNA - Granulosa cells [nTPM]":"38.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.3","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"76.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.6","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"26.8","Single Cell Type RNA - Langerhans cells [nTPM]":"27.8","Single Cell Type RNA - Late spermatids [nTPM]":"5.5","Single Cell Type RNA - Leydig cells [nTPM]":"138.5","Single Cell Type RNA - Macrophages [nTPM]":"26.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"37.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.0","Single Cell Type RNA - Paneth cells [nTPM]":"22.5","Single Cell Type RNA - Peritubular cells [nTPM]":"97.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"52.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"61.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.9","Single Cell Type RNA - T-cells [nTPM]":"10.0","Single Cell Type RNA - Theca cells [nTPM]":"205.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.5","Single Cell Type RNA - Urothelial cells [nTPM]":"19.7"},{"Gene":"PPARG","Gene synonym":["NR1C3","PPARG1","PPARG2","PPARgamma"],"Ensembl":"ENSG00000132170","Gene description":"Peroxisome proliferator activated receptor gamma","Uniprot":["P37231"],"Chromosome":"3","Position":"12287368-12434356","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Nuclear receptors","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Receptor"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant","FDA approved drug targets","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"165.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"284.1","Extravillous trophoblasts":"217.8","Granulosa cells":"232.9","Urothelial cells":"239.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"33.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"198.7","ASC TERT1":"113.7","BEWO":"247.5","CAPAN-2":"111.6","HSkMC":"118.9","PC-3":"112.0","RT4":"157.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004282","HPA051239","HPA063663"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB004282":"AB_628115","HPA051239":"AB_2681400","HPA063663":"AB_2685081"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.41e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.59e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.52e-5"},"Tissue RNA - adipose tissue [nTPM]":"165.1","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"8.7","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"3.0","Tissue RNA - breast [nTPM]":"74.3","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"48.7","Tissue RNA - duodenum [nTPM]":"23.6","Tissue RNA - endometrium 1 [nTPM]":"7.0","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"6.2","Tissue RNA - fallopian tube [nTPM]":"7.0","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"14.6","Tissue RNA - hippocampal formation [nTPM]":"4.0","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"14.3","Tissue RNA - liver [nTPM]":"17.1","Tissue RNA - lung [nTPM]":"28.5","Tissue RNA - lymph node [nTPM]":"4.9","Tissue RNA - medulla oblongata [nTPM]":"3.7","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"14.5","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"7.9","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"43.6","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"40.6","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"5.7","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"5.2","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"15.1","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"35.5","Tissue RNA - testis [nTPM]":"6.9","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"8.1","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"67.7","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"44.0","Cell RNA - A549 [nTPM]":"38.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"198.7","Cell RNA - ASC TERT1 [nTPM]":"113.7","Cell RNA - BEWO [nTPM]":"247.5","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"44.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.1","Cell RNA - CACO-2 [nTPM]":"7.8","Cell RNA - CAPAN-2 [nTPM]":"111.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"4.0","Cell RNA - GAMG [nTPM]":"72.9","Cell RNA - HaCaT [nTPM]":"17.3","Cell RNA - HAP1 [nTPM]":"14.4","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"106.4","Cell RNA - HEK 293 [nTPM]":"20.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"10.3","Cell RNA - HHSteC [nTPM]":"51.8","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"118.9","Cell RNA - hTCEpi [nTPM]":"9.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.8","Cell RNA - hTERT-HME1 [nTPM]":"37.5","Cell RNA - hTERT-RPE1 [nTPM]":"20.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"8.3","Cell RNA - MCF7 [nTPM]":"11.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"99.2","Cell RNA - PC-3 [nTPM]":"112.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"30.6","Cell RNA - RT4 [nTPM]":"157.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"18.8","Cell RNA - SK-BR-3 [nTPM]":"6.7","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"6.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"34.2","Cell RNA - TIME [nTPM]":"35.0","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"10.6","Cell RNA - U-2197 [nTPM]":"4.6","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"3.2","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"4.0","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"3.7","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"284.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"50.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"110.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"93.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"26.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"217.8","Single Cell Type RNA - Fibroblasts [nTPM]":"12.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"83.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.8","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"232.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.7","Single Cell Type RNA - Hepatocytes [nTPM]":"3.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"74.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"19.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"19.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"1.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.3","Single Cell Type RNA - Paneth cells [nTPM]":"84.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.3","Single Cell Type RNA - Spermatocytes [nTPM]":"10.9","Single Cell Type RNA - Spermatogonia [nTPM]":"22.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.9","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.5","Single Cell Type RNA - Urothelial cells [nTPM]":"239.6"},{"Gene":"PRKCQ","Gene synonym":[],"Ensembl":"ENSG00000065675","Gene description":"Protein kinase C theta","Uniprot":["Q04759"],"Chromosome":"10","Position":"6427143-6580301","Protein class":["Cancer-related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Immunity","Inflammatory response"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"33.6","skeletal muscle":"124.5","tongue":"112.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"22.9","dendritic cells":"22.4","NK-cells":"32.0","Oligodendrocyte precursor cells":"24.6","Oligodendrocytes":"75.2","T-cells":"31.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"gdT-cell":"23.0","MAIT T-cell":"18.0","memory CD4 T-cell":"24.5","memory CD8 T-cell":"24.5","naive CD4 T-cell":"19.1","naive CD8 T-cell":"17.9","NK-cell":"13.3","T-reg":"39.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"NK-cells":"13.3","T-cells":"39.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"57.8","JURKAT":"40.0","MOLT-4":"43.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065279","HPA073098"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"HPA065279":"AB_2685453","HPA073098":"AB_2686571"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.27e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"5.3","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"8.5","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"1.6","Tissue RNA - choroid plexus [nTPM]":"12.1","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"8.3","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"3.9","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"5.5","Tissue RNA - hypothalamus [nTPM]":"8.2","Tissue RNA - kidney [nTPM]":"10.9","Tissue RNA - liver [nTPM]":"1.0","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"12.3","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"3.4","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"6.4","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"124.5","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"3.3","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"5.5","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"2.1","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"7.2","Tissue RNA - thymus [nTPM]":"33.6","Tissue RNA - thyroid gland [nTPM]":"14.9","Tissue RNA - tongue [nTPM]":"112.6","Tissue RNA - tonsil [nTPM]":"9.4","Tissue RNA - urinary bladder [nTPM]":"2.2","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"9.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"5.3","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"3.4","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"3.3","Cell RNA - HBEC3-KT [nTPM]":"6.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"3.9","Cell RNA - HEL [nTPM]":"57.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.7","Cell RNA - HL-60 [nTPM]":"2.8","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"3.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"40.0","Cell RNA - K-562 [nTPM]":"12.8","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"43.9","Cell RNA - NB-4 [nTPM]":"8.0","Cell RNA - NTERA-2 [nTPM]":"5.8","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"8.5","Cell RNA - RH-30 [nTPM]":"1.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"11.6","Cell RNA - RT4 [nTPM]":"2.9","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"5.8","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"5.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"7.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"23.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"18.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"24.5","Blood RNA - memory CD8 T-cell [nTPM]":"24.5","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"19.1","Blood RNA - naive CD8 T-cell [nTPM]":"17.9","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"13.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"39.7","Blood RNA - total PBMC [nTPM]":"10.5","Brain RNA - amygdala [nTPM]":"5.3","Brain RNA - basal ganglia [nTPM]":"8.5","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"5.5","Brain RNA - hypothalamus [nTPM]":"8.2","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"6.4","Brain RNA - spinal cord [nTPM]":"5.5","Brain RNA - thalamus [nTPM]":"7.2","Brain RNA - white matter [nTPM]":"9.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.0","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"22.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"5.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"75.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"10.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"31.7","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PTF1A","Gene synonym":["bHLHa29","p48","PTF1-p48"],"Ensembl":"ENSG00000168267","Gene description":"Pancreas associated transcription factor 1a","Uniprot":["Q7RTS3"],"Chromosome":"10","Position":"23192312-23194245","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"47","RNA tissue specific nTPM":{"pancreas":"104.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"2.1","Exocrine glandular cells":"4.8","Spermatocytes":"3.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"0.6","pancreatic cancer":"1.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"U-2 OS":"2.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022612"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 9: U-2 OS - Unknown function","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB022612":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"104.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PTPN2","Gene synonym":["PTPT","TC-PTP","TCELLPTP","TCPTP"],"Ensembl":"ENSG00000175354","Gene description":"Protein tyrosine phosphatase non-receptor type 2","Uniprot":["P17706"],"Chromosome":"18","Position":"12785478-12929643","Protein class":["Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"99.8"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015004","HPA046176"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015004":"AB_2669131","HPA046176":"AB_2679569"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.37e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Tissue RNA - adipose tissue [nTPM]":"23.4","Tissue RNA - adrenal gland [nTPM]":"15.2","Tissue RNA - amygdala [nTPM]":"10.0","Tissue RNA - appendix [nTPM]":"32.8","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"57.2","Tissue RNA - breast [nTPM]":"23.7","Tissue RNA - cerebellum [nTPM]":"21.0","Tissue RNA - cerebral cortex [nTPM]":"17.1","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"22.2","Tissue RNA - duodenum [nTPM]":"18.9","Tissue RNA - endometrium 1 [nTPM]":"16.0","Tissue RNA - epididymis [nTPM]":"20.4","Tissue RNA - esophagus [nTPM]":"20.0","Tissue RNA - fallopian tube [nTPM]":"17.4","Tissue RNA - gallbladder [nTPM]":"22.4","Tissue RNA - heart muscle [nTPM]":"14.7","Tissue RNA - hippocampal formation [nTPM]":"11.0","Tissue RNA - hypothalamus [nTPM]":"10.4","Tissue RNA - kidney [nTPM]":"17.3","Tissue RNA - liver [nTPM]":"25.8","Tissue RNA - lung [nTPM]":"26.3","Tissue RNA - lymph node [nTPM]":"44.4","Tissue RNA - medulla oblongata [nTPM]":"12.3","Tissue RNA - midbrain [nTPM]":"10.4","Tissue RNA - ovary [nTPM]":"26.8","Tissue RNA - pancreas [nTPM]":"33.1","Tissue RNA - parathyroid gland [nTPM]":"14.1","Tissue RNA - pituitary gland [nTPM]":"18.3","Tissue RNA - placenta [nTPM]":"19.5","Tissue RNA - pons [nTPM]":"11.8","Tissue RNA - prostate [nTPM]":"17.6","Tissue RNA - rectum [nTPM]":"24.1","Tissue RNA - retina [nTPM]":"20.2","Tissue RNA - salivary gland [nTPM]":"29.4","Tissue RNA - seminal vesicle [nTPM]":"13.5","Tissue RNA - skeletal muscle [nTPM]":"16.7","Tissue RNA - skin 1 [nTPM]":"21.0","Tissue RNA - small intestine [nTPM]":"19.5","Tissue RNA - smooth muscle [nTPM]":"16.9","Tissue RNA - spinal cord [nTPM]":"10.7","Tissue RNA - spleen [nTPM]":"28.5","Tissue RNA - stomach 1 [nTPM]":"18.0","Tissue RNA - testis [nTPM]":"13.6","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"99.8","Tissue RNA - thyroid gland [nTPM]":"17.5","Tissue RNA - tongue [nTPM]":"11.9","Tissue RNA - tonsil [nTPM]":"43.5","Tissue RNA - urinary bladder [nTPM]":"37.2","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"34.8","Cell RNA - A549 [nTPM]":"20.7","Cell RNA - AF22 [nTPM]":"23.7","Cell RNA - AN3-CA [nTPM]":"7.9","Cell RNA - ASC diff [nTPM]":"26.5","Cell RNA - ASC TERT1 [nTPM]":"47.4","Cell RNA - BEWO [nTPM]":"23.0","Cell RNA - BJ [nTPM]":"22.7","Cell RNA - BJ hTERT+ [nTPM]":"50.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"42.2","Cell RNA - CACO-2 [nTPM]":"45.4","Cell RNA - CAPAN-2 [nTPM]":"48.8","Cell RNA - Daudi [nTPM]":"54.3","Cell RNA - EFO-21 [nTPM]":"37.2","Cell RNA - fHDF\/TERT166 [nTPM]":"23.6","Cell RNA - GAMG [nTPM]":"53.2","Cell RNA - HaCaT [nTPM]":"20.4","Cell RNA - HAP1 [nTPM]":"39.0","Cell RNA - HBEC3-KT [nTPM]":"62.2","Cell RNA - HBF TERT88 [nTPM]":"62.1","Cell RNA - HDLM-2 [nTPM]":"21.2","Cell RNA - HEK 293 [nTPM]":"23.5","Cell RNA - HEL [nTPM]":"38.4","Cell RNA - HeLa [nTPM]":"17.7","Cell RNA - Hep G2 [nTPM]":"47.6","Cell RNA - HHSteC [nTPM]":"36.4","Cell RNA - HL-60 [nTPM]":"91.1","Cell RNA - HMC-1 [nTPM]":"35.1","Cell RNA - HSkMC [nTPM]":"40.2","Cell RNA - hTCEpi [nTPM]":"57.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.3","Cell RNA - hTERT-HME1 [nTPM]":"85.1","Cell RNA - hTERT-RPE1 [nTPM]":"29.2","Cell RNA - HUVEC TERT2 [nTPM]":"24.6","Cell RNA - JURKAT [nTPM]":"58.1","Cell RNA - K-562 [nTPM]":"37.9","Cell RNA - Karpas-707 [nTPM]":"71.6","Cell RNA - LHCN-M2 [nTPM]":"38.6","Cell RNA - MCF7 [nTPM]":"39.9","Cell RNA - MOLT-4 [nTPM]":"91.3","Cell RNA - NB-4 [nTPM]":"74.5","Cell RNA - NTERA-2 [nTPM]":"28.5","Cell RNA - OE19 [nTPM]":"141.7","Cell RNA - PC-3 [nTPM]":"24.0","Cell RNA - REH [nTPM]":"30.4","Cell RNA - RH-30 [nTPM]":"37.3","Cell RNA - RPMI-8226 [nTPM]":"61.9","Cell RNA - RPTEC TERT1 [nTPM]":"40.2","Cell RNA - RT4 [nTPM]":"54.6","Cell RNA - SCLC-21H [nTPM]":"42.3","Cell RNA - SH-SY5Y [nTPM]":"22.0","Cell RNA - SiHa [nTPM]":"46.0","Cell RNA - SK-BR-3 [nTPM]":"26.7","Cell RNA - SK-MEL-30 [nTPM]":"41.8","Cell RNA - SuSa [nTPM]":"25.1","Cell RNA - T-47d [nTPM]":"22.4","Cell RNA - THP-1 [nTPM]":"51.5","Cell RNA - TIME [nTPM]":"18.8","Cell RNA - U-138 MG [nTPM]":"59.8","Cell RNA - U-2 OS [nTPM]":"58.0","Cell RNA - U-2197 [nTPM]":"45.1","Cell RNA - U-251 MG [nTPM]":"49.8","Cell RNA - U-266\/70 [nTPM]":"22.6","Cell RNA - U-266\/84 [nTPM]":"24.5","Cell RNA - U-698 [nTPM]":"77.8","Cell RNA - U-87 MG [nTPM]":"28.3","Cell RNA - U-937 [nTPM]":"49.3","Cell RNA - WM-115 [nTPM]":"25.7","Blood RNA - basophil [nTPM]":"23.7","Blood RNA - classical monocyte [nTPM]":"52.6","Blood RNA - eosinophil [nTPM]":"39.2","Blood RNA - gdT-cell [nTPM]":"37.0","Blood RNA - intermediate monocyte [nTPM]":"47.7","Blood RNA - MAIT T-cell [nTPM]":"50.4","Blood RNA - memory B-cell [nTPM]":"54.4","Blood RNA - memory CD4 T-cell [nTPM]":"43.7","Blood RNA - memory CD8 T-cell [nTPM]":"41.4","Blood RNA - myeloid DC [nTPM]":"62.5","Blood RNA - naive B-cell [nTPM]":"39.5","Blood RNA - naive CD4 T-cell [nTPM]":"31.6","Blood RNA - naive CD8 T-cell [nTPM]":"34.9","Blood RNA - neutrophil [nTPM]":"19.0","Blood RNA - NK-cell [nTPM]":"64.1","Blood RNA - non-classical monocyte [nTPM]":"46.7","Blood RNA - plasmacytoid DC [nTPM]":"53.0","Blood RNA - T-reg [nTPM]":"57.3","Blood RNA - total PBMC [nTPM]":"40.7","Brain RNA - amygdala [nTPM]":"10.0","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"21.0","Brain RNA - cerebral cortex [nTPM]":"17.1","Brain RNA - hippocampal formation [nTPM]":"11.0","Brain RNA - hypothalamus [nTPM]":"10.4","Brain RNA - medulla oblongata [nTPM]":"12.3","Brain RNA - midbrain [nTPM]":"10.4","Brain RNA - pons [nTPM]":"11.8","Brain RNA - spinal cord [nTPM]":"10.7","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"25.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"77.0","Single Cell Type RNA - Astrocytes [nTPM]":"38.5","Single Cell Type RNA - B-cells [nTPM]":"82.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"59.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"106.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"88.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"61.5","Single Cell Type RNA - Bipolar cells [nTPM]":"44.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"37.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"84.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"104.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"54.1","Single Cell Type RNA - dendritic cells [nTPM]":"130.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"55.1","Single Cell Type RNA - Early spermatids [nTPM]":"24.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"51.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"44.8","Single Cell Type RNA - Endothelial cells [nTPM]":"32.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"32.3","Single Cell Type RNA - Erythroid cells [nTPM]":"40.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"81.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"68.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"52.5","Single Cell Type RNA - Fibroblasts [nTPM]":"38.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"78.7","Single Cell Type RNA - granulocytes [nTPM]":"56.4","Single Cell Type RNA - Granulosa cells [nTPM]":"53.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"27.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.3","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"60.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.0","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"99.2","Single Cell Type RNA - Langerhans cells [nTPM]":"92.5","Single Cell Type RNA - Late spermatids [nTPM]":"23.2","Single Cell Type RNA - Leydig cells [nTPM]":"29.2","Single Cell Type RNA - Macrophages [nTPM]":"93.4","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"137.0","Single Cell Type RNA - Muller glia cells [nTPM]":"17.6","Single Cell Type RNA - NK-cells [nTPM]":"128.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"55.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.0","Single Cell Type RNA - Paneth cells [nTPM]":"45.1","Single Cell Type RNA - Peritubular cells [nTPM]":"25.6","Single Cell Type RNA - Plasma cells [nTPM]":"120.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"126.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"55.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"84.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.8","Single Cell Type RNA - Spermatocytes [nTPM]":"23.3","Single Cell Type RNA - Spermatogonia [nTPM]":"61.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"40.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"81.1","Single Cell Type RNA - T-cells [nTPM]":"84.2","Single Cell Type RNA - Theca cells [nTPM]":"65.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.5","Single Cell Type RNA - Urothelial cells [nTPM]":"152.4"},{"Gene":"PTPN22","Gene synonym":["Lyp","Lyp1","Lyp2","PTPN8"],"Ensembl":"ENSG00000134242","Gene description":"Protein tyrosine phosphatase non-receptor type 22","Uniprot":["Q9Y2R2"],"Chromosome":"1","Position":"113813811-113871753","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Immunity"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Diabetes mellitus","Disease variant","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"38.0","lymphoid tissue":"20.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"67.4","dendritic cells":"176.0","NK-cells":"108.1","Plasma cells":"79.6","T-cells":"151.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"69.3","HL-60":"27.7","U-266\/70":"29.2","U-698":"37.5","U-937":"28.4"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"cerebellum":"5.3"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004912","CAB012209","HPA013350"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"CAB012209":null,"HPA004912":"AB_10602069","HPA013350":"AB_10601570"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"38.0","Tissue RNA - breast [nTPM]":"2.3","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"7.5","Tissue RNA - lymph node [nTPM]":"20.3","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"8.6","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"13.2","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"20.0","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"13.5","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"69.3","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"6.5","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"10.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"21.1","Cell RNA - HSkMC [nTPM]":"5.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.8","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"5.1","Cell RNA - HUVEC TERT2 [nTPM]":"10.6","Cell RNA - JURKAT [nTPM]":"17.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"15.7","Cell RNA - LHCN-M2 [nTPM]":"10.3","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"20.1","Cell RNA - NB-4 [nTPM]":"15.7","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"6.7","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"10.0","Cell RNA - TIME [nTPM]":"5.0","Cell RNA - U-138 MG [nTPM]":"16.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"29.2","Cell RNA - U-266\/84 [nTPM]":"6.6","Cell RNA - U-698 [nTPM]":"37.5","Cell RNA - U-87 MG [nTPM]":"11.1","Cell RNA - U-937 [nTPM]":"28.4","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"15.8","Blood RNA - classical monocyte [nTPM]":"4.8","Blood RNA - eosinophil [nTPM]":"25.0","Blood RNA - gdT-cell [nTPM]":"17.0","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"20.1","Blood RNA - memory B-cell [nTPM]":"9.9","Blood RNA - memory CD4 T-cell [nTPM]":"8.4","Blood RNA - memory CD8 T-cell [nTPM]":"13.6","Blood RNA - myeloid DC [nTPM]":"8.7","Blood RNA - naive B-cell [nTPM]":"7.4","Blood RNA - naive CD4 T-cell [nTPM]":"5.0","Blood RNA - naive CD8 T-cell [nTPM]":"12.1","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"11.0","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"5.2","Blood RNA - T-reg [nTPM]":"14.5","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"67.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"176.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"16.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"27.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"17.3","Single Cell Type RNA - Langerhans cells [nTPM]":"26.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"26.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"14.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"108.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"79.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"151.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"RFX6","Gene synonym":["dJ955L16.1","MGC33442","RFXDC1"],"Ensembl":"ENSG00000185002","Gene description":"Regulatory factor X6","Uniprot":["Q8HWS3"],"Chromosome":"6","Position":"116877212-116932161","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adrenal gland":"4.5","intestine":"2.2","pancreas":"2.3","stomach 1":"6.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Enteroendocrine cells":"68.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"1.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"1.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037696"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 17: Intestinal endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037696":"AB_2675616"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"4.5","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"6.5","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"68.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SH2B3","Gene synonym":["IDDM20","LNK"],"Ensembl":"ENSG00000111252","Gene description":"SH2B adaptor protein 3","Uniprot":["Q9UQQ2"],"Chromosome":"12","Position":"111405923-111451623","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"60.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"113.6","Langerhans cells":"130.9","Macrophages":"84.1","monocytes":"67.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"122.2","hTEC\/SVTERT24-B":"140.7","U-87 MG":"211.6","WM-115":"165.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005483"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA005483":"AB_1079260"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.2","Tissue RNA - adrenal gland [nTPM]":"10.9","Tissue RNA - amygdala [nTPM]":"10.2","Tissue RNA - appendix [nTPM]":"21.9","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"60.7","Tissue RNA - breast [nTPM]":"13.3","Tissue RNA - cerebellum [nTPM]":"3.5","Tissue RNA - cerebral cortex [nTPM]":"9.3","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"8.5","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"8.1","Tissue RNA - gallbladder [nTPM]":"18.6","Tissue RNA - heart muscle [nTPM]":"23.4","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"6.5","Tissue RNA - kidney [nTPM]":"14.3","Tissue RNA - liver [nTPM]":"17.4","Tissue RNA - lung [nTPM]":"20.5","Tissue RNA - lymph node [nTPM]":"21.0","Tissue RNA - medulla oblongata [nTPM]":"12.0","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"5.5","Tissue RNA - pancreas [nTPM]":"10.2","Tissue RNA - parathyroid gland [nTPM]":"5.8","Tissue RNA - pituitary gland [nTPM]":"8.0","Tissue RNA - placenta [nTPM]":"24.4","Tissue RNA - pons [nTPM]":"10.0","Tissue RNA - prostate [nTPM]":"7.3","Tissue RNA - rectum [nTPM]":"13.5","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"5.3","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"12.5","Tissue RNA - smooth muscle [nTPM]":"13.6","Tissue RNA - spinal cord [nTPM]":"10.1","Tissue RNA - spleen [nTPM]":"37.1","Tissue RNA - stomach 1 [nTPM]":"7.1","Tissue RNA - testis [nTPM]":"9.5","Tissue RNA - thalamus [nTPM]":"12.1","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"11.1","Tissue RNA - tongue [nTPM]":"9.5","Tissue RNA - tonsil [nTPM]":"15.8","Tissue RNA - urinary bladder [nTPM]":"15.7","Tissue RNA - vagina [nTPM]":"6.0","Tissue RNA - white matter [nTPM]":"14.7","Cell RNA - A-431 [nTPM]":"9.2","Cell RNA - A549 [nTPM]":"5.5","Cell RNA - AF22 [nTPM]":"7.0","Cell RNA - AN3-CA [nTPM]":"7.3","Cell RNA - ASC diff [nTPM]":"23.9","Cell RNA - ASC TERT1 [nTPM]":"35.5","Cell RNA - BEWO [nTPM]":"4.8","Cell RNA - BJ [nTPM]":"29.2","Cell RNA - BJ hTERT+ [nTPM]":"79.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.3","Cell RNA - CACO-2 [nTPM]":"8.4","Cell RNA - CAPAN-2 [nTPM]":"5.2","Cell RNA - Daudi [nTPM]":"15.6","Cell RNA - EFO-21 [nTPM]":"20.3","Cell RNA - fHDF\/TERT166 [nTPM]":"44.6","Cell RNA - GAMG [nTPM]":"73.6","Cell RNA - HaCaT [nTPM]":"1.7","Cell RNA - HAP1 [nTPM]":"5.5","Cell RNA - HBEC3-KT [nTPM]":"16.9","Cell RNA - HBF TERT88 [nTPM]":"35.2","Cell RNA - HDLM-2 [nTPM]":"13.3","Cell RNA - HEK 293 [nTPM]":"2.7","Cell RNA - HEL [nTPM]":"53.2","Cell RNA - HeLa [nTPM]":"2.6","Cell RNA - Hep G2 [nTPM]":"6.2","Cell RNA - HHSteC [nTPM]":"23.3","Cell RNA - HL-60 [nTPM]":"23.5","Cell RNA - HMC-1 [nTPM]":"122.2","Cell RNA - HSkMC [nTPM]":"21.2","Cell RNA - hTCEpi [nTPM]":"3.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"140.7","Cell RNA - hTERT-HME1 [nTPM]":"12.7","Cell RNA - hTERT-RPE1 [nTPM]":"48.4","Cell RNA - HUVEC TERT2 [nTPM]":"119.1","Cell RNA - JURKAT [nTPM]":"12.8","Cell RNA - K-562 [nTPM]":"38.9","Cell RNA - Karpas-707 [nTPM]":"6.1","Cell RNA - LHCN-M2 [nTPM]":"80.2","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"9.7","Cell RNA - NB-4 [nTPM]":"46.7","Cell RNA - NTERA-2 [nTPM]":"11.0","Cell RNA - OE19 [nTPM]":"2.4","Cell RNA - PC-3 [nTPM]":"21.0","Cell RNA - REH [nTPM]":"9.5","Cell RNA - RH-30 [nTPM]":"15.9","Cell RNA - RPMI-8226 [nTPM]":"10.2","Cell RNA - RPTEC TERT1 [nTPM]":"10.5","Cell RNA - RT4 [nTPM]":"3.7","Cell RNA - SCLC-21H [nTPM]":"4.6","Cell RNA - SH-SY5Y [nTPM]":"4.9","Cell RNA - SiHa [nTPM]":"5.4","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"42.2","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"33.4","Cell RNA - TIME [nTPM]":"93.0","Cell RNA - U-138 MG [nTPM]":"20.0","Cell RNA - U-2 OS [nTPM]":"11.3","Cell RNA - U-2197 [nTPM]":"17.4","Cell RNA - U-251 MG [nTPM]":"48.1","Cell RNA - U-266\/70 [nTPM]":"13.9","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"17.6","Cell RNA - U-87 MG [nTPM]":"211.6","Cell RNA - U-937 [nTPM]":"16.6","Cell RNA - WM-115 [nTPM]":"165.3","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"8.4","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"4.8","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"6.6","Blood RNA - plasmacytoid DC [nTPM]":"4.9","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"10.2","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"3.5","Brain RNA - cerebral cortex [nTPM]":"9.3","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"6.5","Brain RNA - medulla oblongata [nTPM]":"12.0","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"10.0","Brain RNA - spinal cord [nTPM]":"10.1","Brain RNA - thalamus [nTPM]":"12.1","Brain RNA - white matter [nTPM]":"14.7","Single Cell Type RNA - Adipocytes [nTPM]":"26.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"26.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"4.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"40.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.6","Single Cell Type RNA - Early spermatids [nTPM]":"13.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.2","Single Cell Type RNA - Endothelial cells [nTPM]":"39.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"8.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"38.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"46.1","Single Cell Type RNA - Hepatocytes [nTPM]":"11.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"40.4","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"113.6","Single Cell Type RNA - Langerhans cells [nTPM]":"130.9","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"84.1","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"67.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.2","Single Cell Type RNA - Paneth cells [nTPM]":"5.9","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"4.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.7","Single Cell Type RNA - Spermatocytes [nTPM]":"12.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"12.1","Single Cell Type RNA - Theca cells [nTPM]":"4.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"SLC30A8","Gene synonym":["ZnT-8","ZNT8"],"Ensembl":"ENSG00000164756","Gene description":"Solute carrier family 30 member 8","Uniprot":["Q8IWU4"],"Chromosome":"8","Position":"116950273-117176714","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"pancreas":"61.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"4.9","Late spermatids":"7.5","Pancreatic endocrine cells":"5.0","Proximal tubular cells":"3.6","Spermatogonia":"5.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"28","RNA cancer specific FPKM":{"breast cancer":"10.6","pancreatic cancer":"15.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"36","RNA cell line specific nTPM":{"U-266\/70":"48.0","U-266\/84":"36.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"4.1"},"Antibody":["HPA076165"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA076165":"AB_2732304"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"4.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"61.8","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"12.9","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"2.0","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"48.0","Cell RNA - U-266\/84 [nTPM]":"36.2","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"7.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TCF7L2","Gene synonym":["TCF-4","TCF4"],"Ensembl":"ENSG00000148737","Gene description":"Transcription factor 7 like 2","Uniprot":["Q9NQB0"],"Chromosome":"10","Position":"112950247-113167678","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"244.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"264.8","Distal enterocytes":"260.0","Extravillous trophoblasts":"231.4","Paneth cells":"211.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"244.9"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"intermediate monocyte":"28.9","non-classical monocyte":"86.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"monocytes":"86.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"midbrain":"67.2","thalamus":"86.6"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"midbrain":"146.8","pons":"97.8","thalamus":"164.3"},"Antibody":["CAB013535","HPA038800"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"CAB013535":"AB_2533167","HPA038800":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-3"},"Tissue RNA - adipose tissue [nTPM]":"28.1","Tissue RNA - adrenal gland [nTPM]":"9.4","Tissue RNA - amygdala [nTPM]":"47.4","Tissue RNA - appendix [nTPM]":"8.6","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"7.6","Tissue RNA - breast [nTPM]":"25.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"18.9","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"22.9","Tissue RNA - duodenum [nTPM]":"20.4","Tissue RNA - endometrium 1 [nTPM]":"25.1","Tissue RNA - epididymis [nTPM]":"6.7","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"18.1","Tissue RNA - gallbladder [nTPM]":"9.4","Tissue RNA - heart muscle [nTPM]":"11.3","Tissue RNA - hippocampal formation [nTPM]":"4.3","Tissue RNA - hypothalamus [nTPM]":"46.9","Tissue RNA - kidney [nTPM]":"9.9","Tissue RNA - liver [nTPM]":"22.4","Tissue RNA - lung [nTPM]":"13.9","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"98.0","Tissue RNA - ovary [nTPM]":"22.9","Tissue RNA - pancreas [nTPM]":"12.4","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"9.6","Tissue RNA - placenta [nTPM]":"17.7","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"21.3","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"14.5","Tissue RNA - seminal vesicle [nTPM]":"13.1","Tissue RNA - skeletal muscle [nTPM]":"8.4","Tissue RNA - skin 1 [nTPM]":"17.2","Tissue RNA - small intestine [nTPM]":"19.3","Tissue RNA - smooth muscle [nTPM]":"16.4","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"23.3","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"244.9","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"12.9","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"3.7","Tissue RNA - urinary bladder [nTPM]":"13.8","Tissue RNA - vagina [nTPM]":"14.3","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"15.0","Cell RNA - A549 [nTPM]":"37.8","Cell RNA - AF22 [nTPM]":"40.7","Cell RNA - AN3-CA [nTPM]":"39.6","Cell RNA - ASC diff [nTPM]":"20.8","Cell RNA - ASC TERT1 [nTPM]":"13.7","Cell RNA - BEWO [nTPM]":"48.5","Cell RNA - BJ [nTPM]":"10.3","Cell RNA - BJ hTERT+ [nTPM]":"20.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.5","Cell RNA - CACO-2 [nTPM]":"24.9","Cell RNA - CAPAN-2 [nTPM]":"45.3","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"11.3","Cell RNA - fHDF\/TERT166 [nTPM]":"19.4","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"10.5","Cell RNA - HAP1 [nTPM]":"14.0","Cell RNA - HBEC3-KT [nTPM]":"17.6","Cell RNA - HBF TERT88 [nTPM]":"9.1","Cell RNA - HDLM-2 [nTPM]":"1.7","Cell RNA - HEK 293 [nTPM]":"13.1","Cell RNA - HEL [nTPM]":"10.4","Cell RNA - HeLa [nTPM]":"25.2","Cell RNA - Hep G2 [nTPM]":"23.6","Cell RNA - HHSteC [nTPM]":"22.0","Cell RNA - HL-60 [nTPM]":"4.2","Cell RNA - HMC-1 [nTPM]":"3.7","Cell RNA - HSkMC [nTPM]":"24.4","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.0","Cell RNA - hTERT-HME1 [nTPM]":"18.2","Cell RNA - hTERT-RPE1 [nTPM]":"29.7","Cell RNA - HUVEC TERT2 [nTPM]":"12.0","Cell RNA - JURKAT [nTPM]":"8.8","Cell RNA - K-562 [nTPM]":"11.0","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"8.2","Cell RNA - MCF7 [nTPM]":"28.0","Cell RNA - MOLT-4 [nTPM]":"6.7","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"29.2","Cell RNA - OE19 [nTPM]":"16.6","Cell RNA - PC-3 [nTPM]":"21.6","Cell RNA - REH [nTPM]":"19.0","Cell RNA - RH-30 [nTPM]":"29.8","Cell RNA - RPMI-8226 [nTPM]":"6.9","Cell RNA - RPTEC TERT1 [nTPM]":"15.2","Cell RNA - RT4 [nTPM]":"20.4","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"12.4","Cell RNA - SiHa [nTPM]":"15.7","Cell RNA - SK-BR-3 [nTPM]":"15.4","Cell RNA - SK-MEL-30 [nTPM]":"17.0","Cell RNA - SuSa [nTPM]":"31.5","Cell RNA - T-47d [nTPM]":"10.0","Cell RNA - THP-1 [nTPM]":"2.2","Cell RNA - TIME [nTPM]":"27.9","Cell RNA - U-138 MG [nTPM]":"6.8","Cell RNA - U-2 OS [nTPM]":"18.7","Cell RNA - U-2197 [nTPM]":"16.9","Cell RNA - U-251 MG [nTPM]":"21.3","Cell RNA - U-266\/70 [nTPM]":"2.6","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"6.5","Cell RNA - U-937 [nTPM]":"8.7","Cell RNA - WM-115 [nTPM]":"14.9","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"4.5","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"28.9","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"4.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"6.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"86.6","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"47.4","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"4.3","Brain RNA - hypothalamus [nTPM]":"46.9","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"98.0","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"244.9","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"62.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.5","Single Cell Type RNA - Astrocytes [nTPM]":"264.8","Single Cell Type RNA - B-cells [nTPM]":"3.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"42.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"35.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"64.9","Single Cell Type RNA - Bipolar cells [nTPM]":"2.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"53.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"54.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"52.9","Single Cell Type RNA - Club cells [nTPM]":"35.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"44.2","Single Cell Type RNA - dendritic cells [nTPM]":"9.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"260.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"39.3","Single Cell Type RNA - Early spermatids [nTPM]":"8.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"140.6","Single Cell Type RNA - Endothelial cells [nTPM]":"46.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"231.4","Single Cell Type RNA - Fibroblasts [nTPM]":"90.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"90.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"64.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"37.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"52.8","Single Cell Type RNA - Hepatocytes [nTPM]":"74.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"87.7","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"99.9","Single Cell Type RNA - Langerhans cells [nTPM]":"20.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"59.0","Single Cell Type RNA - Macrophages [nTPM]":"54.6","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"107.7","Single Cell Type RNA - monocytes [nTPM]":"22.4","Single Cell Type RNA - Muller glia cells [nTPM]":"34.4","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"192.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"59.0","Single Cell Type RNA - Paneth cells [nTPM]":"211.1","Single Cell Type RNA - Peritubular cells [nTPM]":"48.5","Single Cell Type RNA - Plasma cells [nTPM]":"6.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"75.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.1","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"37.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"51.3","Single Cell Type RNA - Spermatocytes [nTPM]":"9.4","Single Cell Type RNA - Spermatogonia [nTPM]":"28.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"61.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"39.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.5","Single Cell Type RNA - T-cells [nTPM]":"6.7","Single Cell Type RNA - Theca cells [nTPM]":"13.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"73.9","Single Cell Type RNA - Urothelial cells [nTPM]":"49.0"},{"Gene":"WFS1","Gene synonym":["DFNA14","DFNA38","DFNA6","DIDMOAD","WFS"],"Ensembl":"ENSG00000109501","Gene description":"Wolframin ER transmembrane glycoprotein","Uniprot":["O76024"],"Chromosome":"4","Position":"6269849-6303265","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract","Deafness","Diabetes insipidus","Diabetes mellitus","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"131.4","Extravillous trophoblasts":"120.2","Granulosa cells":"71.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"100.4","Hep G2":"83.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029128"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029128":"AB_10603460"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.13e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Tissue RNA - adipose tissue [nTPM]":"39.4","Tissue RNA - adrenal gland [nTPM]":"20.2","Tissue RNA - amygdala [nTPM]":"43.7","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"71.2","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"36.0","Tissue RNA - cerebellum [nTPM]":"34.3","Tissue RNA - cerebral cortex [nTPM]":"47.2","Tissue RNA - cervix [nTPM]":"51.9","Tissue RNA - choroid plexus [nTPM]":"34.5","Tissue RNA - colon [nTPM]":"44.8","Tissue RNA - duodenum [nTPM]":"12.2","Tissue RNA - endometrium 1 [nTPM]":"75.4","Tissue RNA - epididymis [nTPM]":"14.0","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"58.6","Tissue RNA - gallbladder [nTPM]":"12.4","Tissue RNA - heart muscle [nTPM]":"64.3","Tissue RNA - hippocampal formation [nTPM]":"35.9","Tissue RNA - hypothalamus [nTPM]":"36.8","Tissue RNA - kidney [nTPM]":"16.8","Tissue RNA - liver [nTPM]":"17.1","Tissue RNA - lung [nTPM]":"43.8","Tissue RNA - lymph node [nTPM]":"5.9","Tissue RNA - medulla oblongata [nTPM]":"34.4","Tissue RNA - midbrain [nTPM]":"43.7","Tissue RNA - ovary [nTPM]":"87.1","Tissue RNA - pancreas [nTPM]":"20.1","Tissue RNA - parathyroid gland [nTPM]":"7.2","Tissue RNA - pituitary gland [nTPM]":"50.2","Tissue RNA - placenta [nTPM]":"16.6","Tissue RNA - pons [nTPM]":"36.6","Tissue RNA - prostate [nTPM]":"34.6","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"14.6","Tissue RNA - seminal vesicle [nTPM]":"36.3","Tissue RNA - skeletal muscle [nTPM]":"16.0","Tissue RNA - skin 1 [nTPM]":"26.8","Tissue RNA - small intestine [nTPM]":"22.0","Tissue RNA - smooth muscle [nTPM]":"17.0","Tissue RNA - spinal cord [nTPM]":"33.7","Tissue RNA - spleen [nTPM]":"29.3","Tissue RNA - stomach 1 [nTPM]":"29.1","Tissue RNA - testis [nTPM]":"31.8","Tissue RNA - thalamus [nTPM]":"44.1","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"48.1","Tissue RNA - tongue [nTPM]":"7.5","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"57.8","Tissue RNA - vagina [nTPM]":"29.1","Tissue RNA - white matter [nTPM]":"32.1","Cell RNA - A-431 [nTPM]":"14.1","Cell RNA - A549 [nTPM]":"35.3","Cell RNA - AF22 [nTPM]":"9.1","Cell RNA - AN3-CA [nTPM]":"33.9","Cell RNA - ASC diff [nTPM]":"37.2","Cell RNA - ASC TERT1 [nTPM]":"10.2","Cell RNA - BEWO [nTPM]":"100.4","Cell RNA - BJ [nTPM]":"23.0","Cell RNA - BJ hTERT+ [nTPM]":"32.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.6","Cell RNA - CACO-2 [nTPM]":"24.8","Cell RNA - CAPAN-2 [nTPM]":"37.2","Cell RNA - Daudi [nTPM]":"5.5","Cell RNA - EFO-21 [nTPM]":"34.3","Cell RNA - fHDF\/TERT166 [nTPM]":"26.3","Cell RNA - GAMG [nTPM]":"74.8","Cell RNA - HaCaT [nTPM]":"8.0","Cell RNA - HAP1 [nTPM]":"6.8","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"6.4","Cell RNA - HDLM-2 [nTPM]":"5.7","Cell RNA - HEK 293 [nTPM]":"14.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"11.0","Cell RNA - Hep G2 [nTPM]":"83.0","Cell RNA - HHSteC [nTPM]":"34.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"33.7","Cell RNA - hTCEpi [nTPM]":"18.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.0","Cell RNA - hTERT-HME1 [nTPM]":"13.6","Cell RNA - hTERT-RPE1 [nTPM]":"12.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.3","Cell RNA - JURKAT [nTPM]":"2.5","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"24.3","Cell RNA - LHCN-M2 [nTPM]":"9.7","Cell RNA - MCF7 [nTPM]":"28.0","Cell RNA - MOLT-4 [nTPM]":"1.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"13.5","Cell RNA - OE19 [nTPM]":"20.3","Cell RNA - PC-3 [nTPM]":"38.0","Cell RNA - REH [nTPM]":"3.4","Cell RNA - RH-30 [nTPM]":"9.6","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"6.7","Cell RNA - RT4 [nTPM]":"52.4","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"15.4","Cell RNA - SiHa [nTPM]":"12.2","Cell RNA - SK-BR-3 [nTPM]":"17.4","Cell RNA - SK-MEL-30 [nTPM]":"13.1","Cell RNA - SuSa [nTPM]":"9.6","Cell RNA - T-47d [nTPM]":"31.5","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"19.9","Cell RNA - U-138 MG [nTPM]":"19.8","Cell RNA - U-2 OS [nTPM]":"22.8","Cell RNA - U-2197 [nTPM]":"19.1","Cell RNA - U-251 MG [nTPM]":"14.8","Cell RNA - U-266\/70 [nTPM]":"26.0","Cell RNA - U-266\/84 [nTPM]":"10.1","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"23.9","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"18.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"3.9","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"43.7","Brain RNA - basal ganglia [nTPM]":"71.2","Brain RNA - cerebellum [nTPM]":"34.3","Brain RNA - cerebral cortex [nTPM]":"47.2","Brain RNA - hippocampal formation [nTPM]":"35.9","Brain RNA - hypothalamus [nTPM]":"36.8","Brain RNA - medulla oblongata [nTPM]":"34.4","Brain RNA - midbrain [nTPM]":"43.7","Brain RNA - pons [nTPM]":"36.6","Brain RNA - spinal cord [nTPM]":"33.7","Brain RNA - thalamus [nTPM]":"44.1","Brain RNA - white matter [nTPM]":"32.1","Single Cell Type RNA - Adipocytes [nTPM]":"38.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"131.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.4","Single Cell Type RNA - Astrocytes [nTPM]":"40.5","Single Cell Type RNA - B-cells [nTPM]":"3.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"42.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"5.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"10.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.6","Single Cell Type RNA - Endothelial cells [nTPM]":"21.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"120.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"71.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.4","Single Cell Type RNA - Hepatocytes [nTPM]":"10.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"19.1","Single Cell Type RNA - Leydig cells [nTPM]":"40.0","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"31.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.9","Single Cell Type RNA - Paneth cells [nTPM]":"1.6","Single Cell Type RNA - Peritubular cells [nTPM]":"57.9","Single Cell Type RNA - Plasma cells [nTPM]":"19.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.1","Single Cell Type RNA - Spermatocytes [nTPM]":"10.8","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.7","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"11.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"ZFP57","Gene synonym":["bA145L22","bA145L22.2","C6orf40","ZNF698"],"Ensembl":"ENSG00000204644","Gene description":"ZFP57 zinc finger protein","Uniprot":["Q9NU63"],"Chromosome":"6","Position":"29672483-29681155","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"8.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"4.8","Erythroid cells":"4.6","Extravillous trophoblasts":"4.4","Ionocytes":"8.2","Late spermatids":"5.9","Pancreatic endocrine cells":"4.0","Spermatogonia":"3.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"testis cancer":"18.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"11.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"11.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"BEWO":"40.3","SuSa":"12.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.95e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"8.9","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"2.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"40.3","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"2.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"12.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"11.1","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"}]