Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCB11 "ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP" ENSG00000073734 "ATP binding cassette subfamily B member 11" O95342 2 168915498-169031324 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 80.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 41.7;Alveolar cells type 2: 44.1;Club cells: 19.3;Early spermatids: 16.5;granulocytes: 24.0;Hepatocytes: 20.4" "Cancer enriched" "Detected in single" 87 "liver cancer: 6.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.6;RT4: 1.6;TIME: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA019035 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Plasma membrane, Cytosol" "HPA019035: AB_1844429" "unprognostic (7.78e-2)" "unprognostic (3.92e-1)" "unprognostic (8.31e-2)" "unprognostic (2.56e-1)" "unprognostic (1.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.00e-2)" "unprognostic (9.71e-2)" "unprognostic (1.18e-1)" "unprognostic (1.72e-2)" "unprognostic (5.64e-3)" "unprognostic (3.71e-1)" "unprognostic (5.26e-6)" "unprognostic (7.12e-2)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" 1.5 0.0 0.3 0.1 0.3 0.0 0.6 0.3 0.5 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 80.8 0.0 0.1 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.4 0.1 0.0 0.0 1.1 0.0 0.0 0.3 0.1 0.0 6.2 0.2 0.0 0.0 0.0 0.1 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.4 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.2 0.2 1.0 0.6 0.5 0.3 0.2 0.3 0.0 41.7 44.1 1.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 19.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 16.5 0.1 0.0 1.8 0.0 2.7 0.8 0.0 0.0 6.6 0.0 0.0 24.0 0.0 0.0 20.4 0.0 0.0 0.3 0.0 0.0 0.3 0.0 9.1 0.0 3.8 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.1 0.0 0.0 8.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.6 ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 123.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 256.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.1" "Lineage enriched" "Detected in many" 7 "B-cells: 8.1" "Group enriched" "Detected in some" 5 "SH-SY5Y: 12.9;WM-115: 25.7" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.7 7.4 0.8 2.5 0.6 0.9 0.5 0.6 0.9 0.3 0.4 1.1 0.4 0.2 0.6 0.6 0.2 0.8 6.6 0.8 0.6 0.6 123.2 0.2 5.9 0.9 0.6 0.4 0.1 0.0 0.2 0.2 1.0 0.5 1.2 0.4 0.6 0.4 7.5 1.4 2.1 0.3 0.6 5.0 0.6 1.0 0.7 0.7 0.5 4.8 5.2 1.2 0.5 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 12.9 0.0 0.6 2.6 0.5 0.2 0.6 0.0 0.2 1.7 0.1 0.0 0.0 0.0 3.2 0.2 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.2 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.6 0.6 0.9 0.8 0.6 0.9 0.6 1.0 0.6 0.7 0.7 1.3 0.0 0.5 0.3 22.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 1.8 0.0 1.1 0.1 0.2 0.0 0.1 0.6 0.2 0.2 1.0 0.0 0.4 0.6 0.0 0.3 2.0 0.0 0.2 0.0 0.0 3.3 256.1 0.5 38.7 1.8 0.0 0.0 5.0 1.2 0.4 0.0 1.0 10.6 3.7 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.4 0.3 0.0 0.5 0.7 0.0 0.2 0.0 0.6 1.2 1.2 0.2 0.0 0.4 0.1 0.7 0.0 0.2 0.0 ABCG8 GBD4 ENSG00000143921 "ATP binding cassette subfamily G member 8" Q9H221 2 43831942-43882988 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "intestine: 31.5;liver: 63.4" "Group enriched" "Detected in some" 4 "Hepatocytes: 32.0;Proximal enterocytes: 13.8" "Cancer enriched" "Detected in some" 30 "liver cancer: 21.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 44 "Hep G2: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA019556 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA019556: AB_1844444" "unprognostic (1.99e-1)" "unprognostic (4.49e-1)" "unprognostic (3.22e-1)" "unprognostic (1.37e-1)" "unprognostic (3.09e-2)" "unprognostic (2.43e-1)" "unprognostic (1.99e-3)" "unprognostic (1.27e-1)" "unprognostic (6.28e-1)" "unprognostic (6.14e-3)" "unprognostic (4.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.68e-1)" "unprognostic (7.86e-3)" "unprognostic (5.03e-1)" "unprognostic (1.50e-1)" 0.1 0.0 0.4 0.1 0.3 0.1 0.0 0.2 1.1 0.0 0.0 0.2 29.8 0.1 0.0 0.0 0.2 0.9 0.0 0.2 0.4 0.3 63.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 31.5 0.0 0.0 0.1 0.3 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.1 0.2 0.4 0.3 0.1 0.4 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.8 0.6 1.8 0.0 0.0 0.1 0.0 1.9 0.1 0.0 0.2 0.7 0.6 0.0 2.7 3.6 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.4 32.0 0.0 0.0 2.8 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 5.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.2 0.0 ACP4 ACPT ENSG00000142513 "Acid phosphatase 4" Q9BZG2 19 50790415-50795219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Hydrolase "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 1.2;testis: 3.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.5;U-266/84: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 16: U-266 - Nucleosome" "unprognostic (9.41e-2)" "unprognostic (1.86e-1)" "unprognostic (4.00e-3)" "unprognostic (3.70e-3)" "unprognostic (7.62e-2)" "unprognostic (3.18e-2)" "unprognostic (3.89e-3)" "unprognostic (5.46e-2)" "unprognostic (2.47e-1)" "unprognostic (5.59e-2)" "unprognostic (3.96e-1)" "unprognostic (1.45e-1)" "unprognostic (2.37e-3)" "unprognostic (2.36e-1)" "unprognostic (4.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 1.5 0.0 0.5 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.9 0.0 0.3 0.2 0.4 0.1 0.2 0.5 0.3 0.1 0.2 0.0 0.5 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.3 0.0 0.2 0.2 0.2 0.1 0.2 2.0 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.8 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 AMBN ENSG00000178522 Ameloblastin Q9NP70 4 70592256-70607288 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Microglial cells: 1.9" "Group enriched" "Detected in some" 7 "cervical cancer: 2.6;endometrial cancer: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HEK 293: 6.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036099 Uncertain Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoplasm "HPA036099: " "unprognostic (3.22e-1)" 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.3 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AMELX "AIH1, AMG" ENSG00000125363 "Amelogenin X-linked" Q99217 X 11293413-11300761 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "urothelial cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "unprognostic (1.76e-1)" "unprognostic (1.00e-1)" "unprognostic (2.00e-1)" 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.3 0.5 0.5 0.4 0.2 0.3 0.2 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 AMTN "RSTI689, UNQ689" ENSG00000187689 Amelotin Q6UX39 4 70518569-70532743 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biomineralization, Cell adhesion" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 28.3;salivary gland: 6.8;stomach 1: 7.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 14.0;Ionocytes: 4.1" "Group enriched" "Detected in many" 11 "cervical cancer: 13.9;head and neck cancer: 38.3;lung cancer: 12.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "GAMG: 16.7;hTERT-RPE1: 23.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036136, HPA036137" Uncertain "Secreted in other tissues" NA NA "Cluster 16: Immune cells - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA036136: AB_2674963, HPA036137: AB_10673614" "unprognostic (1.72e-1)" "unprognostic (2.47e-1)" "unprognostic (2.04e-1)" "unprognostic (2.36e-1)" "unprognostic (3.80e-1)" "unprognostic (1.52e-1)" "unprognostic (1.86e-2)" "unprognostic (7.35e-2)" "unprognostic (2.55e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 6.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.3 0.0 0.1 0.3 0.0 0.0 28.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.7 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.5 23.7 0.1 0.0 0.1 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.5 14.0 0.0 0.0 0.1 0.3 0.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 1.3 0.0 0.0 0.9 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 APC "DP2, DP2.5, DP3, PPP1R46" ENSG00000134982 "APC regulator of WNT signaling pathway" P25054 5 112707498-112846239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.8" "Cell type enhanced" "Detected in many" "Astrocytes: 536.4;Bipolar cells: 196.9;Excitatory neurons: 165.8;Inhibitory neurons: 236.4;Oligodendrocyte precursor cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013349, HPA013362" Supported Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA013349: AB_1844913, HPA013362: " "unprognostic (4.80e-2)" "unprognostic (1.19e-1)" "unprognostic (3.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (7.09e-3)" "unprognostic (1.62e-1)" "unprognostic (8.10e-3)" "unprognostic (2.35e-1)" "unprognostic (4.85e-3)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.02e-2)" "unprognostic (1.07e-1)" "unprognostic (3.35e-1)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" 6.9 4.6 28.4 6.2 26.0 9.1 5.7 23.1 31.0 5.7 0.1 6.7 6.2 5.6 3.3 7.7 4.3 4.9 7.2 52.8 27.4 6.2 5.7 6.2 5.6 32.1 30.7 6.6 4.1 8.5 3.9 5.1 39.0 5.2 6.2 20.0 3.8 4.1 8.5 5.7 8.5 7.5 16.0 6.1 5.0 5.1 37.9 8.5 5.9 11.8 5.9 5.4 3.6 20.9 11.3 10.1 16.8 12.2 13.4 11.3 6.7 17.9 8.5 9.7 11.5 8.2 8.9 22.0 17.0 23.1 15.5 9.0 17.4 14.6 15.9 13.2 12.2 16.8 14.9 6.2 6.6 8.4 8.6 9.3 9.8 16.6 10.8 6.8 13.6 10.2 20.9 7.2 14.3 7.8 9.6 4.2 6.0 6.1 3.6 8.1 20.8 10.7 8.9 14.1 17.0 10.1 16.9 6.5 7.1 6.8 9.1 6.7 22.8 19.6 9.5 19.5 13.6 5.6 9.5 8.2 10.8 15.3 11.2 11.8 2.5 4.9 2.9 1.3 2.4 2.8 1.5 1.9 2.1 3.1 2.4 2.4 11.4 2.9 2.4 2.7 1.5 1.0 28.4 26.0 23.1 31.0 52.8 27.4 32.1 30.7 39.0 16.0 37.9 20.9 40.6 51.3 23.6 536.4 21.9 11.2 8.9 10.1 19.9 196.9 13.1 14.9 56.6 18.6 20.1 0.0 66.7 5.4 28.9 28.6 0.0 18.7 10.5 20.1 27.6 31.2 27.5 17.4 165.8 19.5 6.5 25.9 19.4 29.7 19.0 28.7 26.7 13.9 16.3 79.1 236.4 17.2 2.0 18.9 12.4 5.5 17.7 27.8 17.8 85.3 30.7 23.4 23.7 196.6 150.8 20.3 34.7 19.5 22.9 10.4 37.2 5.1 18.0 41.5 39.5 44.1 34.0 19.2 30.4 26.5 11.6 2.9 22.4 27.1 16.0 8.9 ASCC1 "ASC1p50, CGI-18, Em:AC022392.3, p50" ENSG00000138303 "Activating signal cointegrator 1 complex subunit 1" Q8N9N2 10 72096032-72217134 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038038, HPA057567" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "HPA038038: AB_10674544, HPA057567: " "unprognostic (1.96e-1)" "unprognostic (2.79e-2)" "unprognostic (5.36e-2)" "unprognostic (1.03e-2)" "unprognostic (2.92e-3)" "unprognostic (2.34e-2)" "prognostic unfavorable (3.52e-4)" "unprognostic (1.22e-2)" "unprognostic (8.30e-3)" "unprognostic (3.22e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.52e-1)" "unprognostic (1.39e-1)" "unprognostic (4.34e-2)" "unprognostic (1.74e-1)" "unprognostic (2.66e-1)" "unprognostic (6.64e-2)" 19.0 24.9 18.3 13.9 23.5 7.3 16.4 22.4 24.5 16.1 18.8 14.4 9.0 17.1 16.4 14.3 15.3 13.7 24.8 17.2 20.7 15.2 21.6 13.5 18.5 23.4 20.6 17.9 22.7 14.2 11.9 13.0 23.6 11.9 9.9 15.7 12.8 14.5 29.7 17.1 14.6 12.4 21.7 17.1 14.4 18.4 20.4 22.3 13.4 17.3 16.8 15.7 13.6 30.4 29.3 40.3 25.8 58.1 34.0 37.9 21.1 18.0 33.5 26.5 30.7 31.4 105.3 37.0 35.6 26.3 17.9 38.4 21.1 30.6 26.5 27.2 20.1 24.1 29.1 36.4 32.7 25.2 24.1 33.3 68.9 26.7 45.0 38.1 36.4 40.4 34.8 51.8 35.0 25.7 34.2 36.1 15.7 18.8 8.8 20.1 21.1 27.4 49.8 21.0 27.1 16.9 26.1 65.7 49.4 23.9 21.7 18.5 32.0 15.2 27.1 11.6 19.4 28.4 40.4 45.5 24.6 55.9 10.8 20.4 19.0 35.0 16.5 20.3 17.0 31.4 19.4 17.7 21.0 32.5 27.2 25.8 12.5 26.6 15.4 28.9 29.2 19.0 18.3 23.5 22.4 24.5 17.2 20.7 23.4 20.6 23.6 21.7 20.4 30.4 16.7 9.6 5.8 25.5 20.5 6.2 14.0 22.8 9.6 12.9 9.0 6.3 23.6 10.0 13.4 12.9 14.6 17.7 18.6 4.7 23.5 20.4 27.5 12.1 13.8 13.9 3.6 11.1 33.1 20.0 19.5 16.5 6.6 12.1 12.7 12.6 10.4 22.0 18.2 25.2 42.9 5.2 16.2 24.1 8.7 14.2 20.5 12.7 19.6 27.2 21.4 19.9 16.5 35.7 52.8 14.7 8.4 20.7 14.5 8.0 9.5 11.4 9.8 14.3 13.1 10.8 15.9 27.8 28.2 10.9 7.0 15.2 17.9 18.9 6.5 9.2 ATP8B1 "ATPIC, BRIC, FIC1, PFIC, PFIC1" ENSG00000081923 "ATPase phospholipid transporting 8B1" O43520 18 57646426-57803315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 279.7;Intestinal goblet cells: 180.5;Paneth cells: 116.7;Undifferentiated cells: 185.7;Urothelial cells: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 90.2;RT4: 168.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018673, HPA018674" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA018673: AB_1845207, HPA018674: AB_1845208" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "prognostic favorable (2.60e-4)" "unprognostic (8.81e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-1)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (9.62e-3)" "unprognostic (1.97e-1)" "unprognostic (3.30e-3)" "unprognostic (4.55e-3)" "prognostic favorable (6.35e-4)" "unprognostic (1.88e-1)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (8.60e-3)" 9.1 5.4 1.3 8.5 2.0 1.2 9.5 3.6 3.9 16.3 3.0 76.2 30.3 5.9 3.5 14.8 10.6 18.0 4.4 1.7 1.1 6.6 7.7 8.3 2.2 2.1 1.1 2.1 23.3 9.7 2.7 6.9 2.0 17.6 61.7 0.6 20.6 11.5 1.9 8.4 38.2 8.3 1.0 4.6 46.1 0.6 1.9 1.5 22.0 1.8 3.6 30.0 13.0 3.0 32.0 10.7 0.1 0.6 10.5 19.2 11.9 62.6 63.6 67.4 40.4 8.0 24.3 1.5 19.3 90.2 22.3 44.9 0.2 13.9 64.3 0.2 1.1 0.2 2.6 2.5 2.2 0.4 0.6 2.9 12.6 20.8 34.0 39.5 33.0 0.3 0.3 0.7 34.1 15.6 0.1 0.3 0.3 35.5 3.3 0.3 0.2 0.0 7.9 168.1 0.8 0.7 1.3 32.5 0.1 0.5 10.3 0.6 35.3 48.3 2.0 7.7 14.2 0.4 0.4 0.5 1.1 0.4 2.8 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.1 0.2 0.6 0.0 0.2 0.1 0.0 0.0 1.3 2.0 3.6 3.9 1.7 1.1 2.1 1.1 2.0 1.0 1.9 3.0 25.9 19.2 27.0 11.1 4.1 7.8 66.7 20.6 10.2 0.7 28.4 10.4 5.4 27.1 48.9 40.5 0.0 25.6 0.6 279.7 0.0 27.0 2.8 26.3 4.0 30.8 68.4 0.4 61.2 53.1 2.7 7.1 98.4 40.1 4.5 0.9 33.2 19.1 2.4 6.7 11.7 180.5 22.4 2.8 4.0 0.4 0.3 1.0 7.2 37.5 0.9 0.1 0.0 20.6 10.7 38.5 116.7 0.0 0.9 70.8 58.2 0.2 44.7 1.2 13.1 2.8 20.7 0.3 1.5 28.0 16.3 10.9 1.7 2.3 185.7 119.2 AXIN2 "DKFZp781B0869, MGC126582" ENSG00000168646 "Axin 2" Q9Y2T1 17 65528563-65561648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 33.7;Extravillous trophoblasts: 102.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 33.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 27.2;CACO-2: 52.3;Hep G2: 78.8;OE19: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012283, CAB017783" Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Cytosol "CAB012283: AB_2290204, CAB017783: " "unprognostic (1.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.48e-1)" "unprognostic (9.81e-2)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (4.57e-2)" "unprognostic (8.84e-3)" "prognostic favorable (6.58e-4)" "unprognostic (1.98e-1)" "unprognostic (1.42e-1)" "unprognostic (3.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.74e-1)" "unprognostic (1.25e-1)" 8.7 10.9 6.8 5.4 6.9 0.9 5.3 7.9 7.9 17.2 5.5 12.3 7.1 23.9 5.9 5.9 19.8 6.6 8.0 9.4 6.2 3.7 2.7 17.0 3.5 8.5 7.9 15.0 4.2 4.2 6.2 18.4 5.3 14.0 14.6 3.4 5.2 8.9 14.6 14.9 7.4 17.3 7.3 7.4 13.6 6.7 11.0 17.3 12.3 7.8 2.7 11.4 8.0 5.6 0.0 13.9 27.2 0.5 9.6 4.1 12.0 0.4 1.3 0.9 1.7 52.3 5.0 1.0 1.7 8.0 1.0 0.4 5.7 0.1 1.9 2.4 3.1 0.0 2.4 78.8 1.0 0.1 0.1 2.4 2.1 2.2 0.6 1.6 2.4 5.1 0.2 1.2 1.4 0.3 13.9 0.1 5.3 86.9 0.6 9.9 1.6 0.1 2.6 0.3 8.4 5.5 0.5 0.3 4.8 20.0 1.0 0.3 6.3 5.3 9.6 7.6 1.7 0.1 3.0 3.8 2.5 0.6 2.6 3.2 0.0 0.0 0.1 0.0 0.4 0.5 1.1 0.2 0.0 1.8 2.3 0.4 0.0 1.0 0.0 0.0 0.0 0.3 6.8 6.9 7.9 7.9 9.4 6.2 8.5 7.9 5.3 7.3 11.0 5.6 2.4 0.0 9.0 9.8 1.0 11.2 2.2 1.0 11.4 3.7 5.2 8.1 8.7 1.5 8.1 0.0 4.2 18.1 0.7 15.2 0.0 1.4 33.7 7.8 15.1 5.3 5.4 0.0 8.4 0.9 102.6 10.3 5.6 16.5 0.0 3.1 1.1 2.0 3.8 1.7 8.7 17.4 0.0 0.0 7.5 17.5 6.5 0.6 17.8 9.4 1.0 3.3 0.0 8.0 2.0 0.8 18.9 10.9 0.9 2.9 1.9 0.9 1.3 2.5 13.1 1.6 10.6 6.2 12.9 3.3 5.5 14.2 4.6 3.6 19.8 1.3 BMPR1A "ACVRLK3, ALK3, CD292" ENSG00000107779 "Bone morphogenetic protein receptor type 1A" P36894 10 86756601-86932825 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 142.7;Inhibitory neurons: 79.9;Oligodendrocyte precursor cells: 122.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019398 Approved Approved Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "CAB019398: " "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (3.34e-1)" "unprognostic (9.61e-2)" "unprognostic (1.05e-3)" "unprognostic (9.34e-2)" "prognostic unfavorable (8.93e-4)" "unprognostic (3.64e-1)" "unprognostic (2.38e-2)" "unprognostic (1.53e-1)" "unprognostic (9.24e-2)" "unprognostic (9.42e-2)" "unprognostic (4.32e-2)" "unprognostic (1.80e-1)" "unprognostic (1.47e-1)" "unprognostic (1.01e-2)" "unprognostic (1.07e-1)" 9.1 6.4 4.3 4.5 5.2 0.0 10.3 5.4 5.5 8.1 4.9 9.9 5.4 12.9 11.9 7.8 7.4 9.6 7.8 4.7 6.1 7.0 4.3 7.3 2.9 6.8 5.8 11.6 5.8 9.9 2.6 6.5 6.3 12.5 8.2 4.8 12.1 13.0 7.9 9.3 8.6 12.5 6.2 2.9 7.3 5.2 4.6 2.9 19.1 4.8 3.0 7.9 4.1 6.5 14.6 7.8 27.6 26.8 15.0 10.6 5.5 14.5 18.3 9.4 11.3 11.0 13.1 4.7 6.1 19.2 5.9 15.0 15.8 14.3 14.1 5.5 8.2 5.9 6.9 19.0 10.2 7.4 37.7 10.7 8.5 11.2 9.5 13.9 0.0 8.1 7.6 2.7 12.3 7.0 6.7 7.8 17.6 5.2 4.2 0.0 12.3 0.1 18.9 12.1 3.7 12.8 17.8 8.4 12.6 34.1 15.0 4.1 6.2 7.0 9.8 12.7 13.3 0.3 12.3 5.3 6.5 5.6 6.0 0.3 0.0 0.0 0.3 0.0 0.2 0.3 0.2 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.0 4.3 5.2 5.4 5.5 4.7 6.1 6.8 5.8 6.3 6.2 4.6 6.5 3.5 35.3 22.4 142.7 3.5 12.1 7.1 9.9 17.6 7.5 10.2 10.2 22.6 18.6 10.5 11.0 20.9 14.1 2.3 10.7 1.9 10.6 0.7 10.7 19.7 4.5 18.0 0.0 63.8 9.5 1.0 20.6 19.4 13.9 15.2 22.9 9.3 7.2 3.4 11.8 79.9 13.9 8.2 4.8 6.1 4.1 33.5 2.3 8.8 34.7 0.8 12.9 2.1 122.2 64.3 8.9 4.9 31.2 3.2 13.7 10.6 5.5 16.5 20.4 6.6 20.3 19.2 2.1 6.6 11.5 9.8 5.1 4.3 11.9 11.1 6.7 CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "CF transmembrane conductance regulator" P13569 7 117287120-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.6;intestine: 42.7;pancreas: 210.7" "Group enriched" "Detected in many" 4 "Ductal cells: 485.4;Ionocytes: 252.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "CACO-2: 29.5;MOLT-4: 98.9;U-266/70: 49.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB001951: , HPA021939: AB_1846578, HPA079652: " "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" 0.4 0.0 0.5 4.7 2.0 0.0 0.4 0.7 1.3 8.5 0.0 42.7 36.2 1.1 1.1 0.8 2.2 54.6 0.1 0.3 0.7 2.1 1.6 8.2 0.0 1.1 0.7 0.0 210.7 0.2 0.1 0.6 0.7 2.2 40.7 0.0 21.5 0.5 0.0 1.9 19.9 2.0 1.7 0.0 3.1 1.7 1.0 0.1 0.1 0.0 0.3 0.7 0.0 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 98.9 0.1 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 49.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.7 1.3 0.3 0.7 1.1 0.7 0.7 1.7 1.0 2.9 0.0 6.4 65.6 0.0 0.5 0.0 2.0 2.6 0.0 0.5 0.5 0.0 2.4 55.8 17.8 0.0 0.0 0.0 0.0 45.8 0.0 485.4 3.2 9.6 1.2 0.4 7.2 0.0 2.2 4.5 0.0 0.3 4.1 19.8 1.3 0.1 0.0 0.4 0.0 0.0 1.1 13.9 252.3 0.0 0.0 2.6 0.3 0.1 0.0 1.0 6.7 0.5 0.0 0.5 23.8 14.8 86.4 0.0 0.0 4.0 8.6 0.0 5.6 0.0 0.0 0.0 1.6 2.2 0.5 0.0 0.0 0.0 0.3 0.1 87.3 5.8 COX4I2 "COX4-2, COX4B, COX4L2, COXIV-2, dJ857M17.2" ENSG00000131055 "Cytochrome c oxidase subunit 4I2" Q96KJ9 20 31637912-31645006 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 49.1;placenta: 115.4" "Group enriched" "Detected in some" 5 "Sertoli cells: 414.2;Smooth muscle cells: 191.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "SH-SY5Y: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (2.64e-1)" "unprognostic (2.09e-2)" "unprognostic (2.76e-3)" "unprognostic (2.18e-2)" "unprognostic (4.51e-2)" "prognostic favorable (6.04e-5)" "unprognostic (5.60e-2)" "unprognostic (1.13e-1)" "unprognostic (2.51e-1)" "unprognostic (7.45e-2)" "unprognostic (1.04e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (9.78e-4)" "unprognostic (1.11e-1)" "unprognostic (3.30e-3)" "unprognostic (1.43e-1)" "unprognostic (5.59e-2)" 19.1 1.1 6.7 1.7 6.7 0.0 15.9 6.5 9.1 4.8 6.1 4.7 1.9 7.5 3.9 5.4 4.9 10.6 39.7 6.5 6.7 10.9 1.1 49.1 4.7 6.8 7.0 2.9 2.3 9.3 2.2 115.4 7.0 10.1 2.7 1.1 3.6 4.7 8.7 4.9 5.8 7.1 6.6 1.7 4.2 1.5 7.0 1.8 14.7 19.4 3.0 7.7 6.7 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 6.7 6.5 9.1 6.5 6.7 6.8 7.0 7.0 6.6 7.0 6.6 55.0 0.0 0.0 0.0 0.5 6.4 0.3 0.0 2.2 0.4 0.9 1.9 2.7 0.0 0.0 0.0 0.0 1.1 0.3 0.1 0.0 0.0 0.2 0.1 0.7 23.5 0.0 0.0 0.0 0.0 0.3 9.5 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 7.5 0.7 3.7 0.5 8.8 2.8 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.7 414.2 4.6 191.6 0.1 1.0 0.8 6.7 2.5 1.0 1.0 0.0 0.3 CTHRC1 ENSG00000164932 "Collagen triple helix repeat containing 1" Q96CG8 8 103371538-103382989 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 69.1;gallbladder: 87.8;placenta: 90.1;urinary bladder: 84.6" "Cell type enhanced" "Detected in many" "Endothelial cells: 95.2;Fibroblasts: 181.6;Langerhans cells: 45.9;Melanocytes: 49.8;Smooth muscle cells: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 294.6;fHDF/TERT166: 138.1;HHSteC: 197.1;HSkMC: 406.6;WM-115: 386.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059806, HPA061896" Approved Approved Nucleoplasm "Secreted in other tissues" NA NA 420000 "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA059806: AB_2684130, HPA061896: AB_2684633" "unprognostic (2.04e-2)" "unprognostic (4.58e-1)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (4.17e-2)" "unprognostic (3.64e-2)" "unprognostic (8.63e-2)" "unprognostic (1.12e-2)" "unprognostic (3.73e-2)" "prognostic unfavorable (1.22e-14)" "unprognostic (2.33e-3)" "unprognostic (3.21e-2)" "unprognostic (7.96e-3)" "unprognostic (2.37e-3)" 69.1 2.8 1.6 15.4 1.8 0.5 39.0 5.7 6.3 12.8 0.4 6.6 6.3 18.7 3.3 9.7 5.3 87.8 8.9 1.5 2.3 2.3 0.8 8.9 13.8 2.0 1.6 4.2 3.7 2.2 3.7 90.1 2.5 4.7 6.2 2.4 17.0 5.6 3.6 32.5 3.5 19.7 1.8 2.6 3.6 3.6 1.5 6.2 9.1 4.1 16.0 84.6 6.6 3.3 12.1 0.9 3.3 0.8 90.6 294.6 0.2 34.8 9.3 3.7 5.0 1.1 8.3 1.5 36.6 138.1 0.2 0.4 0.1 0.2 17.7 0.5 0.0 0.5 0.6 19.2 197.1 0.9 0.7 406.6 0.5 30.7 0.4 1.4 60.2 2.3 0.5 91.6 18.7 1.7 17.2 41.1 11.0 0.4 58.0 35.8 30.9 1.1 2.9 0.2 5.7 4.3 0.1 0.2 110.8 12.6 0.1 0.2 49.0 4.6 1.8 4.8 0.4 3.0 0.8 0.6 2.2 0.2 386.9 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.2 0.0 0.1 1.6 1.8 5.7 6.3 1.5 2.3 2.0 1.6 2.5 1.8 1.5 3.3 36.9 3.2 2.3 1.0 6.7 32.0 0.2 12.1 0.0 0.3 0.9 1.4 0.8 1.5 3.6 3.7 0.0 5.6 0.9 0.0 0.0 4.1 0.5 6.4 9.8 95.2 1.2 0.8 2.3 0.6 11.3 181.6 0.0 11.5 0.0 0.5 17.5 0.1 8.0 0.0 2.0 0.0 4.1 0.3 45.9 0.8 12.5 0.9 49.8 3.7 0.6 5.5 1.0 4.5 1.8 1.8 0.0 0.4 24.2 0.8 0.0 0.5 0.8 1.2 0.0 4.7 77.4 4.3 16.5 0.3 27.3 16.6 3.5 1.2 0.2 0.5 CTLA4 "CD, CD152, CELIAC3, CTLA-4, GSE, IDDM12" ENSG00000163599 "Cytotoxic T-lymphocyte associated protein 4" P16410 2 203867771-203873965 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Diabetes mellitus, Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 37.4" "Cell type enriched" "Detected in some" 8 "T-cells: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 7 "T-reg: 44.5" "Lineage enriched" "Detected in single" 445 "T-cells: 44.5" "Cell line enhanced" "Detected in some" "Karpas-707: 1.5;SK-MEL-30: 3.0;U-266/70: 4.3;U-266/84: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.92e-2)" "unprognostic (9.13e-3)" "unprognostic (1.47e-3)" "unprognostic (9.89e-6)" "unprognostic (1.86e-1)" "prognostic favorable (4.48e-5)" "unprognostic (1.02e-1)" "unprognostic (1.75e-2)" "unprognostic (1.84e-3)" "unprognostic (2.65e-3)" "unprognostic (2.77e-1)" "unprognostic (3.76e-1)" "unprognostic (9.86e-10)" "unprognostic (4.13e-2)" "unprognostic (7.45e-2)" "unprognostic (4.94e-2)" "unprognostic (1.19e-2)" 1.1 0.2 0.4 18.5 0.4 6.1 1.0 0.4 0.7 0.6 0.5 1.3 0.3 0.3 0.0 1.6 0.6 5.2 0.5 0.5 0.5 0.6 0.7 2.9 37.4 1.3 0.7 0.1 0.4 0.5 0.3 0.3 1.1 1.5 3.2 0.0 0.5 1.0 0.1 0.7 6.2 0.8 0.6 3.9 2.9 1.1 0.5 10.1 1.1 0.2 17.0 5.8 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 4.3 13.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 6.2 0.8 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 44.5 0.6 0.4 0.4 0.4 0.7 0.5 0.5 1.3 0.7 1.1 0.6 0.5 0.5 0.4 0.0 3.2 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 4.1 0.0 1.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.0 3.3 0.0 2.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 1.0 0.2 0.9 0.1 41.9 0.0 0.0 0.1 CTRC "CLCR, ELA4" ENSG00000162438 "Chymotrypsin C" Q99895 1 15438442-15449242 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 3927 "pancreas: 25708.5" "Cell type enriched" "Detected in some" 9 "Exocrine glandular cells: 6566.4" "Cancer enriched" "Detected in some" 168 "pancreatic cancer: 236.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046920 Enhanced "Secreted to digestive system" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" "HPA046920: AB_2679865" "unprognostic (2.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (8.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (2.94e-2)" "unprognostic (7.60e-2)" "unprognostic (3.34e-1)" "unprognostic (2.00e-1)" "unprognostic (9.55e-11)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "unprognostic (1.50e-1)" "unprognostic (5.99e-3)" 6.5 1.2 0.2 0.2 0.2 0.7 2.9 0.7 0.3 2.7 0.2 1.2 1.1 1.3 0.1 1.9 0.8 0.0 2.3 0.3 0.1 1.2 3.5 1.0 0.3 0.1 0.1 5.6 25708.5 0.0 1.5 0.7 0.2 1.8 0.0 0.1 2.1 0.0 1.0 2.1 1.7 0.0 0.0 2.0 2.3 1.0 0.2 0.0 1.0 0.0 0.0 0.6 1.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.1 0.0 0.0 0.2 0.2 0.7 0.3 0.3 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.2 0.0 0.5 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 17.3 0.0 0.6 1.0 0.7 0.0 0.0 0.2 6566.4 0.1 0.2 0.0 2.1 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.9 0.0 0.0 1.1 1.8 0.0 24.3 0.0 1.0 0.0 0.0 673.8 0.0 0.0 0.1 0.3 0.4 0.1 0.0 0.0 0.0 1.3 3.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.3 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2744.5;Kupffer cells: 1774.9;Macrophages: 1224.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1607.5;fHDF/TERT166: 1436.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 443.9 304.5 65.6 399.7 71.2 87.0 249.0 65.9 77.2 583.2 101.0 312.4 120.8 379.2 116.9 421.6 368.4 230.6 447.0 64.7 95.5 420.6 497.2 428.9 289.6 100.4 90.8 169.1 135.4 79.6 156.8 253.2 107.4 255.5 159.3 33.6 437.3 156.6 237.4 184.7 260.2 316.1 91.9 521.1 194.3 33.2 204.5 60.9 1150.7 99.3 104.0 431.9 477.8 159.2 66.6 283.4 4.0 94.9 657.3 754.5 128.3 885.0 1607.5 258.4 299.5 10.3 294.4 1.5 32.2 1436.1 419.3 279.5 65.3 157.1 195.6 25.9 52.6 58.8 10.0 397.1 479.2 7.7 73.7 296.4 532.2 327.2 427.3 611.5 33.4 20.2 81.7 260.7 194.6 62.5 6.5 23.1 16.3 839.7 91.3 33.6 39.3 202.7 2.6 121.1 4.9 68.6 165.1 68.6 514.6 110.1 97.8 68.7 922.4 766.5 111.9 129.9 259.3 182.7 178.5 4.8 432.5 22.9 249.4 390.6 610.1 90.6 26.3 467.3 35.4 44.1 79.0 31.5 287.4 38.8 48.3 21.5 97.8 31.3 307.6 410.1 78.7 703.7 65.6 71.2 65.9 77.2 64.7 95.5 100.4 90.8 107.4 91.9 204.5 159.2 87.7 109.0 171.4 17.6 54.8 54.7 441.6 563.2 54.7 55.2 94.1 74.5 320.1 165.8 331.7 114.0 41.7 279.4 122.4 147.9 27.4 294.6 15.6 105.8 240.1 163.0 154.7 210.2 36.2 238.2 341.7 155.0 44.4 183.5 179.4 105.9 204.2 239.5 2744.5 58.9 42.8 94.2 158.7 1774.9 436.5 18.5 76.4 1224.3 161.9 70.3 373.1 117.4 24.7 19.1 12.9 363.9 154.0 92.9 47.3 295.5 198.6 351.8 180.8 40.0 39.5 39.4 149.9 10.8 21.0 160.3 40.5 649.6 56.0 32.1 139.6 321.4 CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88265069-88359684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 900.7;Club cells: 471.8;Hofbauer cells: 1100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" No No 19000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB025364: , HPA066610: AB_2685694, HPA068434: AB_2685989" "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (9.30e-5)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-2)" "unprognostic (3.35e-1)" "prognostic favorable (4.80e-4)" "unprognostic (2.93e-1)" "unprognostic (4.35e-2)" "unprognostic (8.10e-2)" "unprognostic (4.07e-2)" 173.2 60.7 9.9 185.1 9.6 71.7 63.4 11.1 24.9 77.9 14.2 143.1 121.0 43.9 28.5 63.3 54.0 182.0 38.5 9.5 10.1 234.7 82.0 272.6 243.7 14.0 11.9 22.1 52.2 42.4 39.3 253.3 13.3 26.0 191.5 3.7 131.6 28.9 18.8 29.6 128.8 88.9 11.5 197.2 73.6 22.8 19.5 63.7 43.6 31.9 140.6 176.3 43.3 21.3 80.3 75.9 27.6 69.9 103.7 286.1 218.4 626.5 1078.4 372.8 270.3 194.7 361.3 117.3 278.9 365.2 84.3 133.6 50.4 269.2 341.9 204.7 82.8 144.5 188.0 233.5 140.2 188.9 108.7 419.1 198.8 284.5 697.4 302.1 377.6 122.3 155.3 145.4 54.8 14.8 89.1 295.1 172.2 551.5 244.9 113.6 30.7 227.0 451.3 106.6 8.8 66.8 81.2 114.9 80.6 185.4 27.9 152.7 149.3 23.5 190.5 156.8 364.6 61.9 81.0 122.9 56.8 435.8 122.4 85.5 203.8 309.7 230.1 415.6 194.9 47.2 99.6 198.2 209.9 26.3 49.5 115.3 215.0 200.5 582.9 425.0 162.7 243.3 9.9 9.6 11.1 24.9 9.5 10.1 14.0 11.9 13.3 11.5 19.5 21.3 78.6 22.4 88.1 0.3 40.8 30.1 7.3 900.7 33.6 1.5 15.9 14.6 4.4 52.9 471.8 40.5 0.0 414.1 330.6 37.9 29.4 29.8 1.6 13.4 135.6 94.8 11.4 29.7 3.0 90.6 159.2 114.4 39.8 21.2 75.3 25.5 26.4 15.8 1100.6 0.0 8.2 19.4 158.7 344.7 200.7 7.9 198.5 391.7 48.0 61.8 185.4 0.5 299.7 13.6 0.4 44.8 72.3 25.6 78.5 8.5 20.2 166.4 93.7 0.8 59.2 4.4 150.8 3.0 11.1 43.3 27.1 227.3 170.6 286.7 44.9 16.1 DGAT1 "ARGP1, DGAT" ENSG00000185000 "Diacylglycerol O-acyltransferase 1" O75907 8 144314584-144326910 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 40.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 213.5;Proximal enterocytes: 700.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 18.4;PC-3: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032853 Enhanced Approved "Nucleoli,Nucleoli rim,Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "Nucleoli, Nucleoli rim" "CAB032853: AB_2090798" "unprognostic (9.24e-3)" "unprognostic (1.61e-1)" "unprognostic (1.75e-2)" "unprognostic (2.23e-1)" "unprognostic (3.49e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (5.10e-2)" "unprognostic (2.78e-2)" "unprognostic (6.88e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-3)" "unprognostic (3.83e-2)" "unprognostic (1.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.67e-3)" 15.0 24.7 4.6 1.8 4.6 5.1 11.8 5.5 5.6 6.1 4.1 16.7 37.0 5.6 1.0 8.6 5.1 2.0 11.7 4.7 4.1 7.9 16.5 6.9 1.8 4.5 4.6 4.3 6.5 3.9 6.5 1.5 4.2 6.6 4.2 1.6 7.4 2.4 11.7 6.9 40.6 1.6 4.1 9.3 8.7 14.7 4.4 2.3 7.4 3.5 1.4 6.7 6.4 4.5 5.2 4.9 2.2 4.1 3.5 1.5 2.9 3.4 3.1 2.9 2.0 11.2 3.1 2.1 12.4 1.9 1.6 4.0 1.8 4.3 0.6 3.7 5.1 3.3 4.2 18.4 2.5 1.0 3.4 2.1 3.2 2.0 2.1 2.1 2.3 7.3 2.9 5.2 1.9 3.7 6.8 4.1 1.1 10.9 21.2 7.7 0.9 3.4 2.8 2.5 2.6 4.2 4.7 5.2 2.3 0.8 2.9 3.3 2.0 1.6 5.6 3.6 2.8 2.3 0.6 0.8 1.8 6.3 3.2 0.0 0.4 0.7 0.2 0.3 0.4 0.1 0.2 0.2 0.5 0.1 0.1 0.0 0.5 0.0 0.4 0.2 0.1 0.2 4.6 4.6 5.5 5.6 4.7 4.1 4.5 4.6 4.2 4.1 4.4 4.5 34.0 16.0 19.0 15.7 8.5 8.0 12.5 6.3 4.0 24.6 21.6 16.0 20.8 12.8 8.7 18.4 29.2 11.3 17.6 213.5 1.9 9.4 19.2 12.3 13.7 26.5 23.4 17.7 11.2 11.9 10.3 9.3 48.4 21.3 7.0 23.9 12.5 57.4 18.8 18.5 12.8 93.6 4.1 25.5 11.8 25.8 6.8 22.8 5.4 8.4 9.2 21.3 4.1 17.6 7.0 13.3 113.4 6.8 18.8 8.1 700.1 7.4 5.6 23.6 0.0 11.9 12.3 27.7 17.4 12.3 9.2 16.4 12.3 41.1 108.0 20.7 DLX3 ENSG00000064195 "Distal-less homeobox 3" O60479 17 49990005-49995224 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 53.8" "Group enriched" "Detected in some" 7 "Cytotrophoblasts: 35.9;Extravillous trophoblasts: 69.1;Syncytiotrophoblasts: 96.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 135.9;SK-BR-3: 44.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA031164 Approved Nucleoplasm,Cytosol NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA031164: AB_10603565" "unprognostic (1.20e-1)" "unprognostic (1.75e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (4.61e-4)" "unprognostic (1.95e-1)" "unprognostic (2.63e-2)" "unprognostic (1.02e-1)" "unprognostic (2.55e-1)" "unprognostic (1.77e-2)" "unprognostic (7.98e-2)" "unprognostic (1.44e-5)" "unprognostic (3.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.49e-1)" "unprognostic (2.20e-1)" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" 0.5 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.5 1.9 0.1 0.1 0.0 0.0 0.3 3.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.4 0.0 0.4 0.9 0.3 0.2 0.6 0.2 7.4 0.4 0.5 0.0 0.0 1.5 0.7 0.0 53.8 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.2 1.8 0.0 3.0 0.4 4.0 0.0 0.5 0.0 0.0 2.6 0.8 0.6 135.9 0.1 0.0 0.0 0.0 1.3 0.2 0.0 1.5 1.6 0.0 17.1 7.1 0.1 0.0 0.0 0.3 0.0 4.2 0.2 0.0 0.0 0.5 0.0 12.7 0.4 0.0 0.0 0.0 0.9 0.1 0.0 1.7 4.1 0.0 0.4 0.5 0.3 0.6 0.0 0.0 0.3 0.0 1.9 15.1 0.1 1.5 44.1 0.0 9.1 17.5 0.9 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.1 0.4 0.9 0.4 0.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 5.0 0.4 1.1 9.1 0.0 3.5 5.3 2.0 0.0 0.2 0.0 0.0 35.9 0.0 0.0 0.0 0.6 0.0 0.2 0.2 0.3 0.0 0.0 0.2 0.0 69.1 0.7 0.0 0.2 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.1 1.0 0.0 2.0 3.4 5.1 96.0 0.1 0.0 0.0 0.5 DSPP "DFNA39, DGI1, DMP3" ENSG00000152591 "Dentin sialophosphoprotein" Q9NZW4 4 87608529-87616873 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Deafness, Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036230 Uncertain "Secreted in other tissues" NA NA 27000 "HPA036230: AB_10672239" "unprognostic (2.34e-1)" "unprognostic (1.08e-2)" "unprognostic (3.01e-1)" "unprognostic (1.27e-1)" "unprognostic (2.21e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EDA "ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, ODT1, XHED, XLHED" ENSG00000158813 "Ectodysplasin A" Q92838 X 69616067-70039472 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 84.3;Oligodendrocyte precursor cells: 30.2;Oligodendrocytes: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;MAIT T-cell: 1.3" "Group enriched" "Detected in many" 5 "monocytes: 1.2;T-cells: 1.3" "Cell line enhanced" "Detected in many" "EFO-21: 5.2;Hep G2: 17.9;OE19: 5.1;RPMI-8226: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA037972, HPA037973" Supported "Vesicles,Lipid droplets" "Secreted - unknown location" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Lipid droplets" "HPA037972: AB_2675761, HPA037973: AB_2675762" "unprognostic (3.76e-2)" "unprognostic (8.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.59e-3)" "unprognostic (7.85e-2)" "unprognostic (1.25e-4)" "unprognostic (4.33e-4)" "unprognostic (5.03e-2)" "unprognostic (1.53e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-2)" "unprognostic (2.01e-1)" "prognostic favorable (1.04e-9)" "unprognostic (8.63e-4)" "unprognostic (7.64e-2)" "unprognostic (9.85e-2)" "unprognostic (2.79e-1)" 4.2 8.5 2.4 0.7 3.0 0.1 2.8 2.2 2.6 4.9 5.2 2.6 0.5 3.0 3.2 1.5 3.8 2.0 10.4 2.1 2.4 3.7 2.1 3.2 0.8 3.2 2.8 4.9 4.2 9.7 1.3 1.8 3.0 3.4 1.1 0.3 2.2 2.2 1.7 4.2 1.1 2.1 2.3 1.4 3.8 1.2 3.1 1.2 6.0 2.0 0.6 2.3 3.9 4.6 0.0 0.6 0.3 2.8 0.5 0.0 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.3 5.2 0.2 0.2 0.5 3.8 1.4 0.0 0.0 4.5 0.0 0.0 17.9 1.0 0.0 1.1 1.8 1.3 0.0 0.9 0.0 0.5 3.5 0.0 4.9 0.0 1.2 0.0 0.0 2.8 5.1 0.3 0.0 1.2 6.0 0.1 0.0 1.5 0.0 0.1 0.3 0.1 2.0 0.3 0.1 0.5 1.7 2.2 2.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.0 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.8 0.0 0.0 0.1 2.4 3.0 2.2 2.6 2.1 2.4 3.2 2.8 3.0 2.3 3.1 4.6 3.3 3.2 0.5 21.2 0.3 3.8 2.6 2.0 6.8 0.2 0.9 1.5 12.1 0.0 1.1 5.5 0.0 0.2 0.1 1.0 0.0 1.3 21.3 4.6 1.2 2.2 1.8 0.0 17.9 1.3 0.2 6.0 5.6 12.2 0.0 0.5 11.0 1.2 4.1 0.0 9.6 0.6 0.0 4.8 1.2 9.2 4.7 2.8 1.8 84.3 0.1 1.3 0.0 30.2 45.9 1.1 0.1 2.2 0.2 2.3 0.4 3.1 1.3 0.1 6.6 10.7 5.4 1.7 3.5 3.2 4.1 0.0 2.1 0.4 0.9 1.5 ENAM AIH2 ENSG00000132464 Enamelin Q9NRM1 4 70628744-70646824 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 7.5;heart muscle: 6.5;kidney: 9.0;skeletal muscle: 4.9" "Group enriched" "Detected in some" 4 "Melanocytes: 33.8;Plasma cells: 13.4" "Group enriched" "Detected in some" 5 "pancreatic cancer: 0.6;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-266/70: 1.2;U-266/84: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA 23000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.52e-2)" "unprognostic (2.80e-3)" "unprognostic (1.87e-1)" "unprognostic (1.02e-2)" "unprognostic (2.78e-2)" "unprognostic (1.02e-1)" "unprognostic (7.94e-3)" "unprognostic (4.73e-2)" "unprognostic (2.06e-1)" "unprognostic (9.06e-4)" "unprognostic (1.01e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.81e-14)" "unprognostic (1.26e-1)" "unprognostic (2.56e-1)" "unprognostic (2.12e-1)" "unprognostic (1.45e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 7.5 0.0 0.3 2.4 6.5 0.0 0.0 9.0 0.5 0.3 0.0 0.0 0.0 0.0 3.6 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.9 0.0 0.2 0.2 0.0 0.1 1.7 0.6 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.1 2.8 0.0 3.7 0.0 0.0 0.0 0.0 3.9 1.0 4.4 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 2.6 0.3 0.1 33.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 13.4 0.0 0.0 4.1 0.0 0.2 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.1 0.0 EPCAM "17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 806.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2317.0;Ductal cells: 999.6;Intestinal goblet cells: 1378.2;Paneth cells: 2437.0;Proximal enterocytes: 2681.1;Undifferentiated cells: 1607.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 538.9;CACO-2: 680.9;CAPAN-2: 944.4;OE19: 911.8;RPTEC TERT1: 398.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" 4.4 12.2 3.1 77.0 4.0 10.2 99.7 1.5 3.1 116.2 1.0 806.0 726.5 33.0 238.9 10.8 114.3 71.1 0.6 3.3 9.2 223.1 3.1 74.7 0.9 2.8 3.2 1.2 125.4 219.5 86.9 1.7 3.4 60.5 751.0 0.6 119.8 52.8 0.1 8.8 769.6 22.2 2.6 1.4 172.4 21.7 10.4 6.4 286.8 0.1 2.8 30.9 4.2 2.6 538.9 5.4 0.4 1.2 0.0 0.0 321.3 0.2 0.0 0.6 0.0 680.9 944.4 0.1 141.5 1.0 0.4 247.3 4.6 62.2 2.0 0.1 56.3 0.3 2.5 261.6 0.1 0.3 0.4 0.0 17.6 0.0 0.0 0.0 0.8 0.0 160.9 0.0 0.3 269.7 0.5 24.0 164.3 911.8 31.4 0.3 0.0 136.9 398.6 231.3 354.0 3.2 4.3 187.7 0.6 132.7 158.3 1.0 0.7 0.3 6.3 2.0 1.1 39.2 0.6 0.8 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.1 4.0 1.5 3.1 3.3 9.2 2.8 3.2 3.4 2.6 10.4 2.6 3.7 310.9 148.1 1.3 7.0 9.3 227.6 127.4 14.2 0.5 184.7 112.9 2.0 243.1 222.8 448.8 0.0 16.4 2.3 2317.0 76.3 999.6 8.6 434.7 35.3 5.8 498.1 23.1 1.1 402.8 6.5 6.3 150.3 445.3 32.5 11.8 1.4 0.6 2.9 0.0 0.4 1378.2 486.2 0.0 5.2 5.6 20.5 5.6 35.6 0.0 11.5 15.7 0.0 0.5 1.2 617.5 2437.0 18.8 1.8 257.9 2681.1 195.9 219.0 0.7 13.1 0.5 13.7 83.5 130.3 33.3 10.4 6.0 9.4 70.3 1607.7 230.7 FAM20A DKFZp434F2322 ENSG00000108950 "FAM20A golgi associated secretory pathway pseudokinase" Q96MK3 17 68535113-68601367 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 50.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 82.4;Early spermatids: 69.0;Hepatocytes: 66.8;Hofbauer cells: 94.0;Late spermatids: 189.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 10.1;BJ hTERT+: 27.3;HSkMC: 21.8;U-2197: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048964 Approved "Secreted in other tissues" NA NA 13000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "HPA048964: AB_2680575" "unprognostic (3.68e-2)" "unprognostic (3.14e-2)" "unprognostic (3.35e-2)" "unprognostic (4.49e-3)" "unprognostic (6.56e-2)" "unprognostic (5.29e-2)" "unprognostic (3.90e-3)" "unprognostic (2.39e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (9.16e-10)" "unprognostic (1.25e-3)" "unprognostic (1.06e-1)" "unprognostic (4.55e-2)" "unprognostic (2.39e-2)" 7.5 1.6 0.4 2.7 0.3 0.6 5.4 0.3 0.6 17.5 2.6 1.6 0.6 12.5 0.1 3.1 6.0 1.3 3.1 0.1 1.1 12.9 50.2 12.6 1.6 0.8 1.7 8.1 1.0 0.3 6.3 2.2 0.7 2.5 0.4 0.1 11.6 0.6 1.6 2.5 2.0 2.3 0.1 4.5 7.8 6.5 3.6 0.4 6.8 0.1 0.5 2.2 5.7 0.7 0.0 0.2 0.0 0.2 1.1 10.1 0.0 0.5 27.3 0.0 0.0 0.0 0.1 0.0 2.0 2.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.1 0.0 21.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.1 0.0 0.0 0.1 0.0 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.4 0.3 0.3 0.6 0.1 1.1 0.8 1.7 0.7 0.1 3.6 0.7 1.4 16.0 82.4 0.7 1.1 2.3 0.1 5.2 0.0 3.2 5.3 0.9 5.2 7.2 21.3 44.1 0.0 0.6 0.4 0.0 0.0 1.2 69.0 6.1 44.4 3.6 0.0 2.7 3.8 0.5 2.2 18.1 42.3 9.7 1.3 2.9 7.5 66.8 94.0 42.1 8.2 0.0 2.0 27.4 3.5 189.3 11.1 26.8 1.8 16.9 1.3 0.2 0.0 4.0 2.1 0.8 0.0 14.7 0.2 0.0 0.0 15.3 0.8 2.8 6.6 3.4 3.0 1.2 0.6 1.2 1.8 2.7 1.0 13.6 0.0 0.1 FAM83H FLJ46072 ENSG00000180921 "Family with sequence similarity 83 member H" Q6ZRV2 8 143723933-143738234 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 70.5;skin 1: 34.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 58.7;hTCEpi: 59.8;MCF7: 118.2;OE19: 62.4;RT4: 70.1;T-47d: 58.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024505, HPA024604" Enhanced Approved Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA024505: AB_1848417, HPA024604: AB_1848418" "unprognostic (3.80e-2)" "unprognostic (3.75e-3)" "unprognostic (6.87e-2)" "unprognostic (1.63e-2)" "unprognostic (3.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.93e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-3)" "unprognostic (3.95e-2)" "unprognostic (9.69e-3)" "prognostic favorable (4.42e-4)" "unprognostic (5.54e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" 2.1 4.0 1.9 2.1 1.7 0.5 4.4 1.2 2.2 11.5 2.6 9.8 8.4 0.8 3.3 70.5 4.7 3.3 0.8 2.0 1.1 11.8 13.5 6.3 0.9 1.6 2.4 0.3 13.9 7.9 5.9 3.5 1.5 7.2 4.3 1.1 17.1 3.8 0.1 34.9 9.1 0.3 1.3 1.7 11.0 2.8 1.5 1.5 14.1 0.0 4.0 8.3 23.2 2.2 47.0 28.3 0.3 0.1 0.1 0.0 16.6 4.0 0.0 2.0 0.7 25.8 53.4 0.0 6.1 1.0 0.0 56.1 3.5 51.9 0.9 0.0 0.2 1.5 58.7 18.3 4.3 0.6 1.7 2.9 59.8 0.2 15.0 0.8 0.0 4.2 22.2 0.1 0.0 118.2 0.8 0.4 4.8 62.4 15.3 0.1 0.1 6.0 16.5 70.1 7.1 0.2 38.3 53.8 7.8 7.5 58.2 8.2 0.3 0.1 7.2 3.9 0.2 0.0 0.0 0.2 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.7 1.2 2.2 2.0 1.1 1.6 2.4 1.5 1.3 1.5 2.2 0.1 32.1 16.5 0.7 0.6 22.8 17.7 21.9 6.8 2.0 18.2 14.0 4.6 14.3 18.9 29.5 2.1 12.8 0.5 38.5 3.9 22.0 1.2 11.4 2.9 1.0 14.4 0.0 1.3 25.9 17.8 1.6 25.0 25.9 0.0 5.4 0.7 25.5 4.7 10.1 0.5 24.3 16.2 2.8 0.8 0.7 0.0 1.3 1.8 0.0 2.8 6.6 2.1 0.5 0.1 42.7 27.2 0.4 0.4 26.4 23.6 7.0 17.4 2.0 0.0 0.2 1.9 1.7 1.0 38.9 26.9 14.6 0.9 1.2 27.8 33.9 FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 1203.7;intestine: 1462.2" "Cell type enhanced" "Detected in many" "Peritubular cells: 500.6;Sertoli cells: 420.7;Smooth muscle cells: 459.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Enhanced "Plasma membrane,Actin filaments,Cytosol" NA NA 730000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: AB_2797215, HPA001016: , HPA001115: AB_1078871, HPA002925: AB_1078869" "unprognostic (1.39e-1)" "unprognostic (9.40e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (6.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.23e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.49e-3)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.88e-4)" 267.4 55.9 14.4 223.2 18.5 157.9 164.2 15.2 43.0 392.1 54.7 1462.2 89.9 1203.7 35.5 454.7 609.4 137.9 108.4 14.8 23.0 70.5 21.2 238.9 65.0 39.9 19.9 236.7 50.5 13.4 30.5 79.2 24.4 369.2 86.9 9.0 80.3 617.2 49.7 124.7 354.6 706.6 21.1 102.7 508.0 33.7 34.0 48.1 85.6 31.2 38.1 1053.9 286.4 21.5 947.2 719.2 246.7 316.1 209.8 278.4 400.9 614.0 680.1 552.5 489.8 469.2 169.4 80.5 1551.4 966.4 970.1 528.3 224.0 538.1 152.7 333.6 77.8 262.2 914.9 159.7 375.9 309.3 324.9 266.1 126.1 825.5 327.0 533.8 417.1 94.9 74.7 538.7 401.3 210.7 148.5 93.1 258.3 97.9 470.9 147.8 221.2 71.6 197.2 193.4 52.9 119.7 515.8 80.2 381.1 187.3 79.1 96.3 1016.6 625.2 586.8 640.0 1147.1 333.7 212.8 162.3 580.3 202.4 638.7 7.6 24.9 11.8 32.6 23.1 21.2 10.2 15.6 29.2 22.4 4.6 6.0 14.3 3.6 10.5 34.2 2.7 20.7 56.2 14.4 18.5 15.2 43.0 14.8 23.0 39.9 19.9 24.4 21.1 34.0 21.5 105.1 57.7 38.7 30.0 76.9 124.3 85.9 127.8 85.4 3.5 40.9 153.5 34.5 38.6 26.1 35.0 0.0 24.6 257.7 2.6 1.9 272.0 2.1 33.8 186.3 107.0 1.8 39.7 11.8 133.1 90.9 137.9 13.3 55.8 26.0 334.5 81.8 4.3 120.3 11.8 8.6 2.5 22.4 141.0 263.0 13.7 122.4 227.7 88.9 30.9 207.9 39.4 270.8 8.0 2.6 347.4 1.5 500.6 98.7 96.1 1.9 3.0 9.1 4.3 420.7 118.3 459.3 4.1 8.9 48.8 73.6 20.0 172.3 134.7 3.3 35.3 GPR68 OGR1 ENSG00000119714 "G protein-coupled receptor 68" Q15743 14 91232532-91253925 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Amelogenesis imperfecta, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 12.2" "Cell type enhanced" "Detected in many" "dendritic cells: 8.0;Hofbauer cells: 17.3;Langerhans cells: 22.6;NK-cells: 12.3;T-cells: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 22.9" "Group enriched" "Detected in many" 9 "NK-cells: 20.2;T-cells: 22.9" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 9.0;U-87 MG: 28.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.44e-1)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "prognostic favorable (3.06e-5)" "unprognostic (3.20e-2)" "unprognostic (1.43e-1)" "unprognostic (9.10e-2)" "unprognostic (1.58e-1)" "unprognostic (6.84e-2)" "unprognostic (9.63e-2)" "unprognostic (9.42e-2)" "unprognostic (3.73e-1)" "unprognostic (8.31e-9)" "unprognostic (1.70e-2)" "unprognostic (3.19e-2)" "unprognostic (9.44e-2)" "unprognostic (2.78e-3)" 3.7 1.0 2.5 5.7 1.9 1.4 2.3 3.6 4.9 2.2 0.8 3.1 1.8 1.3 0.5 8.7 1.0 3.7 2.4 1.8 3.3 3.1 1.0 4.9 5.9 2.2 2.6 0.3 0.7 0.9 12.2 3.1 3.7 2.7 1.5 0.2 3.8 0.4 0.7 6.2 2.9 2.0 0.2 4.2 5.7 2.1 2.7 1.2 1.7 0.2 2.8 7.5 3.9 1.4 0.2 0.1 0.6 0.0 0.0 0.9 0.6 1.1 0.6 0.0 0.0 0.2 1.0 0.9 0.4 9.0 0.0 1.0 0.0 0.1 0.2 0.3 0.1 0.0 0.1 0.2 0.0 0.6 4.1 0.4 0.1 4.8 0.0 4.4 0.4 2.9 5.8 0.8 3.9 1.2 0.8 6.4 0.1 0.0 0.1 0.3 0.3 0.2 0.1 0.3 3.1 4.4 0.1 0.1 0.0 0.2 1.5 0.4 2.8 6.1 0.1 1.1 0.4 1.0 1.3 0.2 28.6 1.1 0.1 0.0 0.1 0.1 22.9 0.0 13.8 0.5 5.0 13.5 0.2 0.4 0.6 4.5 2.3 20.2 0.0 0.0 8.7 4.1 2.5 1.9 3.6 4.9 1.8 3.3 2.2 2.6 3.7 0.2 2.7 1.4 1.1 0.0 4.8 0.3 0.7 3.6 0.2 4.2 0.6 0.5 0.8 0.8 1.7 0.0 1.0 0.0 0.0 0.1 8.0 0.1 0.0 0.0 5.4 0.5 0.2 6.9 0.0 2.7 4.1 0.2 0.1 4.3 0.0 0.3 0.0 0.1 0.4 0.0 17.3 0.0 2.1 0.0 0.0 0.0 22.6 1.6 0.3 3.0 3.6 0.0 0.6 0.0 12.3 1.0 0.3 2.9 0.0 4.5 1.3 0.1 0.0 0.4 0.4 0.2 0.0 0.1 1.1 3.4 0.4 0.9 3.0 0.7 13.1 0.2 0.0 0.3 GREM2 "CKTSF1B2, DAND3, FLJ21195, Prdc" ENSG00000180875 "Gremlin 2, DAN family BMP antagonist" Q9H772 1 240489573-240612155 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Heparin-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 31.4;liver: 26.3" "Cell type enriched" "Detected in many" 9 "Syncytiotrophoblasts: 298.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 32.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB009920 Approved "Secreted to blood" NA NA 12000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB009920: AB_2279266" "unprognostic (2.01e-1)" "unprognostic (2.49e-1)" "unprognostic (7.41e-2)" "unprognostic (7.58e-3)" "unprognostic (2.82e-3)" "unprognostic (1.34e-1)" "unprognostic (8.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.31e-2)" "unprognostic (6.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.97e-2)" "unprognostic (3.07e-8)" "unprognostic (1.22e-1)" "unprognostic (2.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.38e-2)" 0.8 1.7 2.1 9.7 2.9 0.1 3.4 0.1 6.1 0.9 0.0 17.1 10.8 9.6 2.2 17.1 1.4 31.4 0.0 1.3 1.8 2.3 26.3 1.2 0.2 2.1 1.7 6.6 0.2 22.9 2.1 4.0 1.9 2.6 20.1 5.8 4.2 1.8 7.3 3.6 14.9 6.4 1.3 3.2 9.3 0.3 2.8 0.3 0.5 0.7 0.2 3.8 0.5 2.0 0.0 0.0 0.1 0.0 1.9 2.4 0.0 6.1 6.5 0.0 0.0 0.0 0.0 0.0 0.0 32.3 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 2.2 0.0 2.8 1.3 0.0 0.0 3.9 0.5 0.8 0.4 1.0 0.0 0.0 3.3 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 2.9 0.1 6.1 1.3 1.8 2.1 1.7 1.9 1.3 2.8 2.0 0.2 0.0 0.0 0.3 0.2 4.7 0.0 0.0 0.6 20.8 14.0 0.1 0.6 0.0 0.0 0.0 12.5 7.4 0.6 0.6 0.0 0.0 0.0 2.3 1.2 0.6 1.2 0.0 28.6 0.0 1.7 17.4 0.0 13.7 0.0 0.1 0.7 20.4 1.5 0.0 30.5 0.1 0.0 0.3 6.2 0.2 0.0 0.2 1.8 3.7 0.0 0.4 1.0 1.5 1.2 0.1 0.1 4.5 0.1 0.6 0.0 0.0 0.7 6.7 0.0 0.2 1.4 2.4 2.7 0.6 3.7 298.0 1.6 2.3 0.6 0.1 GUCY2C "GUC2C, STAR" ENSG00000070019 "Guanylate cyclase 2C" P25092 12 14612632-14696599 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "intestine: 68.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 34.4;Enteroendocrine cells: 176.7;Intestinal goblet cells: 56.0;Paneth cells: 97.9;Proximal enterocytes: 81.5;Undifferentiated cells: 47.6" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.9;stomach cancer: 9.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 1.4;CACO-2: 1.1;CAPAN-2: 1.7;SiHa: 1.6" "Region enhanced" "Detected in some" "midbrain: 1.8" "Low region specificity" "Detected in all" "HPA037655, HPA073759" Uncertain Uncertain Vesicles NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA037655: AB_10672388, HPA073759: " "unprognostic (1.08e-1)" "unprognostic (2.12e-1)" "unprognostic (3.58e-2)" "unprognostic (2.11e-2)" "unprognostic (1.60e-2)" "unprognostic (5.67e-3)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.14e-2)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (1.58e-1)" "unprognostic (5.40e-2)" "unprognostic (2.35e-4)" "unprognostic (8.02e-2)" "unprognostic (1.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.98e-1)" 0.5 0.2 0.1 3.4 0.3 0.5 0.0 0.2 0.1 0.0 3.0 37.2 68.2 0.3 0.0 1.9 0.0 0.9 2.2 0.2 0.3 0.4 0.3 0.2 0.4 0.4 0.3 0.0 2.2 0.0 0.0 0.2 0.4 0.3 41.4 0.1 0.6 0.0 0.7 1.0 66.5 1.4 0.5 0.2 1.9 0.4 0.3 0.0 0.5 0.0 0.3 0.5 0.2 0.5 0.4 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.1 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.2 1.6 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.3 1.1 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.2 0.1 0.3 0.2 0.1 0.2 0.3 0.4 0.3 0.4 0.5 0.3 0.5 0.0 0.0 0.0 1.3 6.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 34.4 0.0 0.0 0.1 0.1 0.0 0.0 176.7 0.0 1.4 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 56.0 0.0 0.3 0.3 0.2 0.0 0.3 0.0 1.0 0.3 0.0 0.0 1.0 0.2 0.4 97.9 0.0 0.1 0.0 81.5 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 47.6 0.0 HLA-DQA1 "CELIAC1, HLA-DQA" ENSG00000196735 "Major histocompatibility complex, class II, DQ alpha 1" P01909 6 32628179-32647062 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 333.9;lymphoid tissue: 335.8" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 4114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 666.6" "Group enriched" "Detected in all" 19 "B-cells: 287.6;dendritic cells: 666.6;monocytes: 257.6" "Cell line enriched" "Detected in some" 7 "HDLM-2: 1419.1" HPA012315 Enhanced NA NA 200000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA012315: AB_1853930" "unprognostic (4.24e-3)" "unprognostic (1.47e-2)" "unprognostic (1.43e-2)" "unprognostic (7.94e-3)" "unprognostic (1.72e-1)" "unprognostic (6.07e-2)" "unprognostic (3.26e-1)" "unprognostic (5.81e-3)" "unprognostic (2.84e-2)" "unprognostic (1.17e-1)" "unprognostic (4.65e-2)" "unprognostic (1.15e-1)" "unprognostic (5.36e-2)" "unprognostic (6.74e-2)" "unprognostic (2.27e-1)" "unprognostic (7.43e-2)" "unprognostic (1.57e-1)" 61.7 45.7 2.3 111.0 2.2 7.1 41.6 2.4 2.8 49.9 5.2 76.8 0.1 27.7 32.2 32.1 29.1 127.4 20.8 1.6 5.1 39.6 95.1 333.9 335.8 4.3 2.6 18.6 15.0 2.6 15.2 13.7 2.7 15.1 115.8 1.9 34.8 7.8 7.5 30.0 74.0 19.2 5.4 180.0 103.3 12.2 3.4 234.3 26.0 0.0 322.3 175.9 16.3 11.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 213.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1419.1 0.9 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 4.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 2.4 0.4 0.0 0.1 0.6 0.6 63.2 1.5 156.1 24.4 0.0 0.0 1.9 105.8 0.5 2.4 257.6 1.0 287.6 3.3 16.5 666.6 274.1 0.4 4.3 3.0 8.2 68.3 162.7 21.6 129.0 2.3 2.2 2.4 2.8 1.6 5.1 4.3 2.6 2.7 5.4 3.4 11.1 67.9 12.8 86.3 0.0 972.8 50.2 0.4 4.3 4.6 0.1 9.8 28.6 2.1 7.2 19.4 0.0 2.1 0.8 179.8 0.9 1.9 4.6 0.6 0.5 0.4 97.4 0.0 38.3 0.1 4.6 2.4 14.7 10.7 0.9 50.4 0.8 12.8 0.6 381.0 0.0 0.1 0.4 2.0 518.6 4114.3 1.3 3.1 874.3 71.2 12.2 957.1 1.0 4.1 0.0 0.2 2.1 0.1 0.0 96.1 1.5 1.8 6.5 27.3 2.5 6.6 1.2 5.3 0.0 0.7 2.5 41.6 2.1 56.0 1.2 2.7 7.6 HLA-DQA2 HLA-DXA ENSG00000237541 "Major histocompatibility complex, class II, DQ alpha 2" P01906 6 32741391-32747198 "Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 20.8;lymphoid tissue: 27.1" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 1196.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (4.06e-3)" "unprognostic (2.46e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-2)" "unprognostic (2.69e-1)" "unprognostic (5.44e-2)" "unprognostic (2.64e-1)" "unprognostic (2.57e-2)" "unprognostic (8.85e-2)" "unprognostic (4.40e-1)" "unprognostic (1.04e-1)" "unprognostic (7.67e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-2)" "unprognostic (3.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.48e-2)" 10.9 4.5 0.0 0.0 0.0 0.0 7.2 0.0 0.0 3.1 0.0 3.9 0.0 2.1 0.0 3.0 2.8 0.1 2.3 0.0 0.0 5.8 1.7 20.8 0.0 0.0 0.0 0.9 1.2 0.0 2.5 0.0 0.0 2.5 0.0 0.0 3.4 0.0 1.4 8.4 11.6 0.0 0.0 27.1 2.9 0.6 0.0 0.3 3.7 0.0 0.3 3.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.1 3.2 3.6 0.0 179.2 23.5 0.3 1.8 1.2 0.0 2.5 1.3 0.5 0.0 7.5 3.7 0.0 0.2 144.1 0.1 0.0 0.2 0.7 0.1 0.2 20.6 2.4 0.4 0.0 0.0 0.8 1.6 0.0 0.3 0.0 0.8 2.2 0.3 110.0 0.0 0.0 0.0 0.0 78.9 1196.5 2.0 1.2 243.1 24.9 0.0 125.3 0.0 8.2 0.0 0.0 0.2 0.0 0.0 9.5 0.0 0.0 11.2 12.4 0.0 6.6 0.7 1.2 0.1 0.3 0.1 23.3 0.4 13.8 0.0 0.0 0.7 HLA-DQB1 "CELIAC1, HLA-DQB, IDDM1" ENSG00000179344 "Major histocompatibility complex, class II, DQ beta 1" 6 32659467-32668383 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 179.1;lymphoid tissue: 301.8" "Cell type enhanced" "Detected in many" "B-cells: 995.1;Langerhans cells: 4144.8;Macrophages: 1090.5;monocytes: 1038.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 153.5;intermediate monocyte: 142.9;memory B-cell: 159.2;myeloid DC: 386.3;naive B-cell: 169.1;plasmacytoid DC: 116.5" "Group enriched" "Detected in all" 6 "B-cells: 169.1;dendritic cells: 386.3;monocytes: 153.5" "Cell line enriched" "Detected in some" 6 "HDLM-2: 599.9" HPA013667 Enhanced Supported "Golgi apparatus,Rods & Rings" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Rods & Rings" "Golgi apparatus" "HPA013667: AB_1853932" "unprognostic (8.60e-3)" "unprognostic (1.91e-2)" "unprognostic (5.91e-2)" "unprognostic (9.85e-3)" "unprognostic (4.48e-1)" "unprognostic (5.30e-2)" "unprognostic (4.75e-2)" "unprognostic (1.06e-2)" "unprognostic (2.51e-2)" "unprognostic (1.48e-1)" "unprognostic (3.48e-2)" "unprognostic (3.94e-1)" "unprognostic (1.34e-2)" "unprognostic (3.13e-1)" "unprognostic (4.16e-1)" "unprognostic (2.43e-1)" "unprognostic (1.40e-1)" 56.6 23.9 2.2 77.8 2.2 40.0 45.3 2.7 3.1 19.9 3.0 45.8 0.2 18.9 126.9 21.3 22.2 43.6 21.6 2.0 3.6 34.3 37.1 179.1 301.8 4.7 3.8 7.4 14.3 10.6 21.3 10.1 2.9 17.1 39.0 1.7 24.2 11.9 9.6 31.8 78.0 11.2 4.6 139.3 128.0 7.0 3.1 108.2 26.3 0.0 122.3 89.9 16.9 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 93.9 2.2 0.0 0.0 19.2 0.0 19.2 0.0 599.9 13.4 0.0 0.0 0.0 0.0 0.2 7.8 0.0 3.0 0.0 0.0 0.0 0.0 2.9 0.0 1.8 0.0 7.2 0.1 0.9 0.1 0.0 0.0 0.0 0.1 0.2 0.0 1.3 0.0 0.1 1.6 1.1 1.4 0.0 3.3 10.9 0.2 0.0 0.6 0.8 0.4 68.7 2.1 66.0 47.1 0.1 0.0 0.3 153.5 27.9 12.8 142.9 6.6 159.2 6.9 20.0 386.3 169.1 0.4 6.3 11.8 10.4 41.1 116.5 41.1 217.0 2.2 2.2 2.7 3.1 2.0 3.6 4.7 3.8 2.9 4.6 3.1 5.5 162.9 41.7 181.1 0.0 995.1 89.9 8.7 23.1 31.3 5.1 16.8 32.1 3.2 27.1 40.7 18.4 10.4 1.4 188.2 10.3 7.9 38.8 16.5 4.1 1.0 135.3 22.8 37.2 0.2 20.0 3.0 18.8 41.8 5.2 38.5 7.9 25.0 2.3 422.1 0.0 0.8 24.7 12.2 487.3 4144.8 7.5 6.5 1090.5 97.8 8.4 1038.0 1.1 25.7 0.0 0.1 28.3 27.4 9.8 86.9 8.7 417.9 18.5 53.0 2.7 6.6 4.8 9.6 2.7 2.5 18.5 66.3 3.0 84.5 0.9 36.1 49.1 ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3;skeletal muscle: 80.0;tongue: 64.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 153.8;Alveolar cells type 2: 202.5;Basal prostatic cells: 153.5;Basal respiratory cells: 125.9;Pancreatic endocrine cells: 195.2;Spermatocytes: 286.0;Urothelial cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 139.2;RPTEC TERT1: 269.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" 0.1 0.0 0.0 1.9 0.0 0.0 20.2 0.0 0.0 2.7 0.0 8.0 8.4 5.4 1.7 14.2 3.4 14.8 0.6 0.0 0.0 68.3 0.1 45.3 0.0 0.0 0.0 0.0 3.3 32.2 1.8 5.5 0.0 5.1 7.4 0.0 3.9 8.9 80.0 2.6 6.3 0.3 0.0 0.0 18.7 0.1 0.0 0.0 4.7 64.5 3.0 44.9 6.5 0.0 14.5 0.2 0.0 0.1 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.1 139.2 0.1 0.8 0.1 0.0 28.7 0.0 45.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 31.4 0.0 0.1 0.4 0.1 0.0 0.0 0.0 3.8 4.3 0.0 0.0 0.0 9.0 0.0 0.0 10.9 0.0 269.9 45.7 0.0 0.1 0.1 43.7 0.0 1.6 0.5 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 153.8 202.5 0.0 0.0 10.5 153.5 125.9 46.1 0.0 35.5 31.0 38.7 10.0 60.4 71.7 0.0 13.6 0.5 30.3 0.0 57.5 89.4 9.6 0.7 2.6 0.0 0.0 0.3 105.4 7.0 2.6 37.8 24.4 3.8 0.0 1.1 1.0 2.2 0.0 0.2 11.6 24.4 0.3 0.4 48.3 2.8 2.2 1.8 0.0 2.0 1.7 0.0 0.5 0.1 195.2 25.6 1.2 0.0 57.3 10.0 1.9 17.7 0.1 0.0 5.7 3.8 286.0 3.0 42.2 8.5 4.7 2.1 0.0 12.4 129.3 KLK4 "EMSP, EMSP1, KLK-L1, PRSS17, PSTS" ENSG00000167749 "Kallikrein related peptidase 4" Q9Y5K2 19 50906352-50910738 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Hydrolase, Protease, Serine protease" "Amelogenesis imperfecta, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 32 "prostate: 286.4" "Cell type enriched" "Detected in some" 15 "Prostatic glandular cells: 106.1" "Cancer enriched" "Detected in many" 55 "prostate cancer: 463.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 6.4;HaCaT: 7.9;OE19: 7.3;SK-BR-3: 5.1" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 4.5" HPA051839 Enhanced "Secreted in male reproductive system" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 35: Glandular cells - Unknown function" "HPA051839: AB_2681632" "unprognostic (3.58e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-3)" "unprognostic (1.66e-3)" "unprognostic (3.11e-2)" "unprognostic (4.35e-1)" "unprognostic (3.18e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-2)" "unprognostic (8.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.20e-3)" "unprognostic (3.27e-3)" "unprognostic (2.21e-2)" "unprognostic (1.64e-2)" "unprognostic (1.34e-1)" 0.4 2.9 0.4 1.5 0.3 1.1 1.7 1.7 1.2 6.5 0.0 3.0 7.3 4.4 1.1 2.1 0.6 1.0 0.1 0.3 0.8 0.6 1.2 0.3 0.8 1.6 0.8 0.1 0.9 1.0 0.0 0.3 1.6 286.4 3.6 0.5 4.8 2.7 3.5 8.9 5.1 0.3 0.5 0.3 1.9 1.2 0.6 0.1 3.8 1.3 0.8 1.2 0.2 0.5 4.1 1.6 0.2 0.2 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.5 6.4 0.4 0.3 0.1 0.2 7.9 0.0 4.2 0.0 1.1 1.1 1.3 3.8 1.4 0.0 1.4 1.7 0.0 1.9 0.0 0.0 0.2 0.0 0.3 0.7 3.3 0.0 1.0 0.1 2.0 0.1 7.3 0.3 0.3 0.4 0.9 0.0 2.6 0.0 0.4 0.3 5.1 0.0 0.2 4.0 0.3 0.9 0.2 0.2 1.0 0.2 2.0 0.9 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.7 1.2 0.3 0.8 1.6 0.8 1.6 0.5 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.3 3.6 0.0 0.0 0.6 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 2.6 0.1 0.0 0.0 0.1 0.2 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.7 0.0 0.0 0.0 0.4 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 106.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.0 0.6 0.0 0.0 3.3 1.0 2.6 KRT18 ENSG00000111057 "Keratin 18" P05783 12 52948871-52952906 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 3698.8;Ductal cells: 6583.8;Exocrine glandular cells: 4826.1;Extravillous trophoblasts: 5496.7;Pancreatic endocrine cells: 6071.5;Syncytiotrophoblasts: 7643.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "basophil: 76.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 76.7" "Cell line enhanced" "Detected in many" "A549: 5639.4;BEWO: 3818.0;CACO-2: 6249.4;CAPAN-2: 4576.4;MCF7: 8470.0;SK-BR-3: 4583.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 12.1" "CAB000008, CAB000030, HPA001605" Enhanced Supported Cytosol NA NA 140000000 "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" Cytosol "CAB000008: , CAB000030: , HPA001605: AB_2666381" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (3.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.25e-1)" "unprognostic (7.26e-3)" "unprognostic (4.09e-3)" "prognostic unfavorable (5.06e-4)" "unprognostic (8.81e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (3.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.19e-1)" "unprognostic (1.11e-2)" "unprognostic (1.13e-2)" 170.3 29.0 2.6 77.5 1.4 1.5 209.8 5.3 1.6 243.5 34.8 424.1 324.3 27.8 226.0 118.4 193.5 180.6 38.3 2.2 6.9 247.2 519.5 177.8 8.6 26.1 4.3 16.4 570.2 79.5 251.9 474.5 30.3 183.3 492.3 0.6 323.4 129.5 2.1 44.5 370.7 23.4 2.5 28.5 289.9 8.3 13.9 10.3 244.1 1.4 27.8 199.7 62.2 2.5 2065.1 5639.4 1.1 7.9 0.7 1.1 3818.0 313.3 349.5 368.4 104.6 6249.4 4576.4 1.4 839.8 318.4 196.5 487.2 79.1 2228.5 217.9 2.6 138.2 19.4 865.7 1743.9 942.1 0.6 1.3 13.6 202.9 323.8 437.1 1046.9 399.0 3.4 511.4 0.2 0.3 8470.0 3.8 37.3 471.0 2740.1 457.9 3.0 0.3 236.1 1803.3 1144.9 65.6 3.7 512.7 4583.8 18.8 2696.0 2446.8 6.6 137.9 5.0 441.8 6.9 68.3 1.1 7.3 4.3 0.9 1.2 36.4 76.7 0.3 2.4 0.6 0.2 2.2 4.6 4.5 1.2 2.2 7.4 11.1 4.1 3.2 2.5 0.0 0.1 0.4 2.9 2.6 1.4 5.3 1.6 2.2 6.9 26.1 4.3 30.3 2.5 13.9 2.5 14.4 862.2 286.4 0.3 29.8 14.8 1605.7 912.1 447.3 0.1 814.6 615.6 5.3 1252.5 877.3 623.5 0.0 3698.8 14.2 1942.9 275.9 6583.8 1.0 462.3 60.3 77.8 642.3 15.4 0.0 4826.1 5496.7 203.5 971.5 742.4 48.9 51.2 57.1 610.9 308.3 1.7 0.0 2492.6 1969.3 9.8 13.8 3.8 10.5 28.3 208.1 1.0 41.5 6.2 0.0 0.0 0.0 6071.5 2164.1 0.0 13.7 1205.1 1912.3 718.5 500.8 0.6 0.0 0.6 298.6 2.7 26.0 395.7 6.7 7643.5 38.1 45.0 1635.0 1512.1 KRT8 "CARD2, CK8, CYK8, K2C8, K8, KO" ENSG00000170421 "Keratin 8" P05787 12 52897187-52949954 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1335.5;stomach 1: 800.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4302.8;Ductal cells: 6037.3;Exocrine glandular cells: 5457.6;Extravillous trophoblasts: 5323.4;Pancreatic endocrine cells: 5278.1;Paneth cells: 4937.3;Proximal enterocytes: 6802.6;Syncytiotrophoblasts: 5268.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 6130.6;BEWO: 3998.7;CACO-2: 7686.4;CAPAN-2: 4774.8;MCF7: 10521.8;SK-BR-3: 5126.4;T-47d: 4325.7" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 10 "spinal cord: 44.0" "CAB000131, CAB001696, HPA049866" Enhanced Supported "Intermediate filaments" NA NA 1700000000 "Cluster 15: NK-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Intermediate filaments" "CAB000131: AB_2281144, CAB001696: , HPA049866: AB_2680923" "unprognostic (5.72e-2)" "unprognostic (2.29e-1)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "unprognostic (2.76e-2)" "unprognostic (4.86e-3)" "unprognostic (3.10e-2)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (8.99e-2)" "unprognostic (2.08e-2)" "unprognostic (2.83e-2)" "unprognostic (3.18e-1)" "unprognostic (3.68e-1)" "unprognostic (1.19e-2)" 135.0 43.6 2.2 158.6 1.3 1.0 113.8 2.0 1.6 183.4 21.3 1079.2 1112.0 34.7 66.4 48.2 134.3 217.5 147.8 1.9 1.9 240.2 463.9 172.5 7.9 8.3 4.5 10.3 654.1 59.9 278.7 368.7 8.8 151.6 564.2 0.4 318.0 73.6 1.5 49.3 1335.5 50.6 0.4 16.3 800.1 7.6 4.9 47.6 237.5 0.3 13.8 209.0 36.7 1.7 2787.7 6130.6 0.2 7.8 0.7 3.2 3998.7 11.1 47.9 6.1 6.3 7686.4 4774.8 1.1 1130.2 14.7 6.9 947.1 17.6 752.6 5.9 4.6 130.8 4.3 1184.4 2234.2 212.8 1.2 2.4 9.5 12.6 14.8 50.8 419.9 17.0 1.0 484.7 1.7 0.1 10521.8 6.5 10.6 418.5 2740.6 132.8 3.8 2.2 15.2 1198.1 1354.5 129.9 5.0 1063.2 5126.4 7.8 1263.8 4325.7 10.5 18.8 5.7 443.4 9.3 10.0 1.6 7.0 7.6 3.3 1.7 13.4 1.3 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.1 0.7 0.2 0.1 0.1 0.4 0.5 0.1 1.7 0.1 0.2 2.2 1.3 2.0 1.6 1.9 1.9 8.3 4.5 8.8 0.4 4.9 1.7 7.7 400.6 176.5 0.3 26.9 6.0 1948.0 684.7 303.3 2.3 521.6 342.8 30.2 1069.5 734.8 491.1 0.0 2208.2 8.5 4302.8 297.4 6037.3 13.9 419.2 41.0 42.3 942.5 8.6 0.5 5457.6 5323.4 94.7 1740.1 557.1 76.3 88.0 24.3 310.9 252.2 1.7 0.5 2876.3 1625.5 9.9 7.2 69.9 8.1 22.2 131.6 0.0 55.0 3.4 1.0 1.0 0.3 5278.1 4937.3 1.9 6.6 994.7 6802.6 569.1 594.8 4.3 0.0 2.2 167.4 2.0 11.4 258.9 1.7 5268.8 33.4 13.4 2337.3 1542.5 LAMB3 "BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa" ENSG00000196878 "Laminin subunit beta 3" Q13751 1 209614870-209652425 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Amelogenesis imperfecta, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.2;urinary bladder: 73.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 370.0;Basal respiratory cells: 447.6;Pancreatic endocrine cells: 853.8;Urothelial cells: 392.7" "Cancer enhanced" "Detected in all" "head and neck cancer: 223.9" "Region enriched" "Detected in many" 7 "cerebral cortex: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 353.8;HaCaT: 538.2;HBEC3-KT: 1315.0;hTCEpi: 412.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA007584, HPA008069, CAB078183" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 20000 "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB078183: AB_2665825, HPA007584: , HPA008069: AB_1079228" "prognostic favorable (8.43e-4)" "unprognostic (3.08e-2)" "unprognostic (1.46e-2)" "unprognostic (2.88e-2)" "unprognostic (8.00e-2)" "unprognostic (1.60e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.62e-5)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.55e-4)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.02e-1)" "unprognostic (2.38e-1)" "unprognostic (6.01e-2)" "unprognostic (4.92e-3)" 10.9 16.0 2.6 13.1 2.9 10.7 20.7 0.9 21.3 13.2 0.5 26.2 31.5 18.0 2.6 47.2 16.4 11.9 6.8 2.9 2.1 16.3 9.3 28.4 1.2 1.5 1.5 1.1 4.2 0.1 1.7 5.8 1.6 25.9 16.6 0.2 41.5 24.1 6.8 42.1 43.7 2.3 1.7 1.0 73.2 1.0 1.9 5.8 1.2 0.3 13.2 73.1 32.6 2.8 178.4 25.8 0.0 0.4 18.1 11.7 1.0 5.1 15.4 6.0 9.1 68.9 353.8 0.1 15.1 3.7 8.9 538.2 0.1 1315.0 9.1 13.1 1.4 1.1 86.9 1.1 2.4 1.0 1.3 2.6 412.8 19.1 253.4 11.7 6.4 0.1 2.5 6.7 1.9 0.3 0.2 1.2 0.6 81.0 74.0 0.2 17.1 165.4 70.9 109.0 0.5 0.5 73.9 8.5 15.4 1.0 2.0 9.7 138.3 29.1 61.3 1.0 104.6 1.7 3.4 0.4 42.2 0.8 2.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 2.6 2.9 0.9 21.3 2.9 2.1 1.5 1.5 1.6 1.7 1.9 2.8 0.4 221.2 67.7 1.6 1.2 109.7 370.0 447.6 159.9 0.3 11.5 64.4 8.4 4.3 168.5 47.8 0.0 1.1 0.4 247.5 0.0 180.5 6.0 50.8 10.0 3.5 7.8 0.4 2.5 153.0 1.4 7.5 195.7 135.0 18.4 0.2 0.4 3.9 2.0 3.3 2.3 71.7 18.3 0.3 30.0 10.9 1.8 9.9 8.8 0.0 2.1 0.4 0.0 1.0 1.7 853.8 229.1 0.7 2.1 185.0 111.9 2.3 52.2 0.3 0.0 5.3 10.4 0.3 0.6 51.7 26.0 0.5 4.0 0.0 63.1 392.7 LBR "DHCR14B, TDRD18" ENSG00000143815 "Lamin B receptor" Q14739 1 225401502-225428925 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "DNA-binding, Oxidoreductase, Receptor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 248.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062236 Enhanced Supported "Nuclear membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear membrane" "HPA062236: AB_2684721" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (2.14e-3)" "unprognostic (1.32e-2)" "unprognostic (7.96e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (7.30e-4)" "unprognostic (3.60e-2)" "unprognostic (1.11e-2)" "unprognostic (3.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (6.42e-2)" "unprognostic (2.08e-1)" "unprognostic (5.45e-1)" "unprognostic (8.32e-2)" "unprognostic (2.78e-1)" 28.6 9.1 8.8 53.2 9.7 95.7 17.1 9.3 11.9 27.3 9.2 61.4 40.7 47.0 44.4 29.7 31.8 21.7 10.0 8.5 10.1 19.4 47.3 19.2 81.6 12.0 9.8 19.4 16.9 5.6 6.5 27.6 11.2 23.8 46.2 5.3 11.1 36.7 9.8 13.8 39.9 41.4 10.2 41.5 28.2 20.5 9.5 105.5 11.8 12.8 70.7 32.3 23.0 13.1 122.2 42.0 154.9 69.3 64.8 39.7 77.3 31.2 39.2 65.0 69.0 87.2 207.2 248.4 66.6 32.8 38.6 88.8 114.2 32.9 98.5 142.2 107.1 61.4 40.4 81.5 39.9 274.7 105.5 34.3 21.3 58.9 52.0 33.1 82.9 117.4 189.6 164.6 44.4 16.3 254.9 156.6 140.6 121.8 14.2 164.9 141.4 234.0 75.6 52.7 40.6 53.4 52.7 39.6 26.6 68.2 53.3 181.0 50.5 17.6 91.7 49.3 115.9 56.6 83.0 274.5 24.3 120.5 61.2 83.6 44.3 67.3 43.6 31.6 50.9 39.0 43.5 48.8 38.4 39.5 42.4 52.9 211.4 41.3 25.2 21.5 61.9 69.8 8.8 9.7 9.3 11.9 8.5 10.1 12.0 9.8 11.2 10.2 9.5 13.1 98.1 28.9 36.4 13.4 86.4 27.0 33.4 17.3 21.6 4.5 11.9 11.0 8.5 48.6 34.4 31.3 6.2 40.5 98.3 33.4 5.9 23.6 1.2 31.5 31.0 53.1 27.0 248.9 10.5 19.8 23.9 29.0 29.0 53.9 10.1 24.0 48.5 73.6 44.4 11.8 14.3 43.0 12.2 88.5 18.1 3.4 33.8 71.7 26.6 19.7 56.0 11.6 82.4 37.2 34.1 20.6 24.6 32.4 74.0 32.9 19.3 26.0 26.0 10.4 39.5 13.9 46.6 21.0 26.7 68.4 35.5 11.1 81.3 13.2 73.8 36.7 LRP6 ADCAD2 ENSG00000070018 "LDL receptor related protein 6" O75581 12 12116025-12267044 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 96.6;Oligodendrocyte precursor cells: 108.0;Oligodendrocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004490, HPA029925" Enhanced NA NA 390000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 68: Oligodendrocytes - Mixed function" "CAB004490: AB_627894, HPA029925: AB_10601768" "unprognostic (1.80e-1)" "unprognostic (3.72e-1)" "unprognostic (2.76e-1)" "unprognostic (1.91e-1)" "unprognostic (6.11e-2)" "unprognostic (1.07e-1)" "unprognostic (4.56e-2)" "unprognostic (1.37e-2)" "unprognostic (3.35e-2)" "unprognostic (6.98e-2)" "unprognostic (1.82e-1)" "unprognostic (5.00e-2)" "unprognostic (1.55e-1)" "unprognostic (2.44e-2)" "unprognostic (3.16e-1)" "unprognostic (1.23e-2)" "unprognostic (2.47e-1)" 3.7 2.2 2.0 1.2 3.9 0.2 4.5 2.5 2.0 6.6 13.5 4.6 2.8 6.5 1.9 2.0 4.4 2.8 3.3 2.0 2.8 4.4 7.9 4.6 0.8 2.2 2.7 5.4 4.9 6.2 2.6 8.3 1.7 3.4 2.8 2.8 6.8 3.2 4.5 3.4 2.7 4.1 1.8 0.9 3.4 2.1 2.8 1.2 4.5 4.6 1.0 3.4 5.3 2.9 3.9 13.3 9.9 5.3 6.1 4.0 7.8 5.8 5.4 4.6 5.3 6.5 3.6 0.0 2.8 5.6 3.8 3.7 14.6 3.7 8.7 0.0 3.9 4.1 4.9 3.2 2.1 5.7 2.8 3.2 2.0 6.9 5.4 5.1 4.8 4.1 5.0 0.0 3.0 3.2 4.2 1.1 14.4 2.2 1.7 5.3 9.2 1.0 6.8 7.6 2.0 5.6 7.4 2.5 6.0 11.5 2.0 3.7 6.9 3.6 13.2 2.6 4.9 0.0 0.0 1.9 2.9 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 3.9 2.5 2.0 2.0 2.8 2.2 2.7 1.7 1.8 2.8 2.9 21.6 41.7 49.5 96.6 1.0 15.4 8.6 11.9 9.6 28.2 20.1 19.0 15.4 11.5 16.6 14.7 22.9 3.7 0.5 20.4 1.9 9.0 1.0 18.0 39.0 25.9 10.8 0.4 58.2 13.7 3.2 24.0 25.5 29.1 0.0 32.8 22.1 46.7 2.3 6.7 58.0 12.9 10.2 2.4 6.0 5.1 30.4 1.7 14.2 35.6 0.6 19.9 1.0 108.0 97.0 11.3 20.5 38.7 1.6 14.7 15.1 5.2 6.0 29.0 0.0 21.5 17.3 21.5 26.4 11.0 13.8 3.4 1.9 23.7 14.4 8.1 LTBP3 LTBP2 ENSG00000168056 "Latent transforming growth factor beta binding protein 3" Q9NS15 11 65538559-65558930 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 61.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 293.8;U-87 MG: 157.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (8.50e-3)" "unprognostic (4.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.59e-1)" "unprognostic (2.24e-2)" "unprognostic (9.22e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-2)" "unprognostic (1.04e-2)" "unprognostic (4.52e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.24e-2)" 65.4 80.1 44.0 21.4 46.1 11.2 68.0 42.0 56.1 120.0 42.2 103.7 16.8 130.8 36.7 36.7 112.6 39.9 131.2 37.6 41.4 84.5 48.8 72.2 24.7 57.0 49.0 155.5 70.1 44.7 111.0 25.5 45.4 109.0 8.5 12.8 64.2 56.3 54.6 39.6 55.8 35.7 51.7 58.1 62.0 20.3 46.9 17.6 114.0 31.0 12.1 84.9 88.0 54.0 16.5 65.9 8.7 43.2 60.7 97.0 8.5 64.7 43.6 8.2 5.3 25.3 85.5 2.0 53.6 64.2 20.4 71.9 11.8 12.2 3.7 9.5 26.4 15.9 25.2 26.2 40.3 2.2 13.4 109.9 4.9 12.1 1.5 293.8 31.9 5.2 4.9 12.7 6.0 39.4 10.9 5.9 7.6 14.6 81.2 29.3 1.1 32.1 6.7 5.5 2.9 41.8 17.3 24.9 35.3 3.7 46.0 5.8 107.0 24.8 32.2 42.5 17.6 13.9 27.1 1.4 157.8 2.6 52.3 0.2 7.3 2.9 8.8 11.2 14.1 61.2 12.6 10.4 8.9 47.6 10.5 11.2 2.9 10.8 13.2 17.8 14.2 7.8 44.0 46.1 42.0 56.1 37.6 41.4 57.0 49.0 45.4 51.7 46.9 54.0 47.1 12.8 11.7 64.0 26.8 73.8 27.7 22.0 50.7 55.7 42.2 43.1 16.7 35.8 16.2 40.5 2.1 24.7 24.4 19.7 21.5 28.1 1.1 19.3 37.5 29.8 30.6 11.2 21.3 12.0 10.5 86.1 14.8 25.3 24.1 92.5 37.5 61.6 20.7 28.6 17.9 15.1 8.2 11.0 34.4 4.3 86.6 14.6 30.2 17.8 11.5 71.4 24.7 29.7 20.2 18.1 15.0 123.8 20.9 35.8 25.3 15.7 8.2 14.3 39.5 89.4 44.0 9.5 37.5 46.9 79.3 16.3 24.4 26.0 20.4 26.5 MMP20 ENSG00000137674 "Matrix metallopeptidase 20" O60882 11 102576832-102625332 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Amelogenesis imperfecta" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 7 "Early spermatids: 91.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "OE19: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "Cluster 21: OE19 - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (4.62e-3)" "unprognostic (2.61e-2)" "unprognostic (1.68e-3)" "unprognostic (1.75e-1)" "unprognostic (2.13e-1)" "unprognostic (3.06e-1)" "unprognostic (2.97e-2)" "unprognostic (6.75e-2)" "unprognostic (9.58e-5)" "unprognostic (6.10e-2)" "unprognostic (2.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 91.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 12.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 6.6 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.4 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 MSX1 "HOX7, HYD1, OFC5" ENSG00000163132 "Msh homeobox 1" P28360 4 4859665-4863936 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 57.0;choroid plexus: 98.0" "Group enriched" "Detected in many" 6 "Adipocytes: 118.4;Endometrial ciliated cells: 364.0;Glandular and luminal cells: 462.0" "Cancer enriched" "Detected in all" 17 "endometrial cancer: 246.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 47.9;EFO-21: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB026198, HPA063895, HPA073604" Enhanced Supported Nucleoplasm NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB026198: , HPA063895: AB_2685145, HPA073604: AB_2686617" "unprognostic (1.12e-1)" "unprognostic (1.93e-2)" "unprognostic (3.39e-2)" "prognostic favorable (1.64e-7)" "unprognostic (9.13e-2)" "unprognostic (1.16e-3)" "unprognostic (4.07e-3)" "unprognostic (3.81e-2)" "unprognostic (1.48e-2)" "unprognostic (2.21e-3)" "unprognostic (4.78e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.18e-5)" "unprognostic (4.35e-2)" "unprognostic (2.06e-1)" "unprognostic (2.34e-3)" "unprognostic (1.33e-2)" 18.4 6.0 12.2 0.7 11.8 0.2 12.8 12.2 16.9 57.0 98.0 1.8 0.5 17.5 0.3 0.9 9.6 1.3 10.3 18.8 12.2 2.9 0.5 4.3 0.6 17.2 11.8 3.5 2.3 0.4 21.1 4.1 11.8 5.5 0.1 0.6 8.8 3.6 20.1 5.2 1.1 3.2 15.1 4.5 2.0 0.7 13.0 0.2 9.2 2.0 0.4 11.2 14.5 12.3 2.5 1.5 0.5 2.8 8.0 5.1 8.9 6.1 2.8 3.5 1.7 47.9 15.3 0.3 21.4 4.4 17.0 0.1 10.6 0.0 1.2 2.0 12.2 0.1 8.0 17.4 0.6 0.1 1.4 1.0 0.8 2.6 0.9 1.1 0.8 4.1 7.9 0.3 1.9 1.2 1.3 2.4 0.2 0.7 11.1 6.4 6.4 0.6 0.2 1.5 0.4 0.3 5.4 0.3 4.0 0.8 0.9 2.1 2.0 4.1 9.1 13.0 9.9 1.0 0.9 5.7 2.6 3.1 4.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 12.2 11.8 12.2 16.9 18.8 12.2 17.2 11.8 11.8 15.1 13.0 12.3 118.4 0.0 0.0 17.3 0.5 7.1 2.4 0.3 4.6 0.8 8.6 24.3 5.5 0.0 0.0 0.0 4.2 0.3 1.6 3.9 0.0 0.2 0.4 364.0 35.7 48.1 0.0 0.0 1.1 0.9 0.1 34.8 1.1 462.0 0.0 1.1 5.7 0.2 0.5 0.0 1.2 2.5 0.0 0.6 8.8 0.0 1.2 4.4 16.0 3.7 0.0 0.7 0.0 1.0 0.3 0.3 0.1 0.4 1.6 3.3 0.6 0.5 0.0 0.7 0.0 13.6 18.2 0.8 1.5 2.6 4.7 0.3 4.8 14.6 2.6 2.0 MUTYH MYH ENSG00000132781 "MutY DNA glycosylase" Q9UIF7 1 45329163-45340893 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA008732 Uncertain Supported Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA008732: AB_1854219" "unprognostic (6.30e-3)" "unprognostic (7.12e-2)" "unprognostic (6.29e-2)" "unprognostic (8.80e-2)" "unprognostic (3.43e-1)" "unprognostic (5.16e-3)" "prognostic unfavorable (4.76e-8)" "unprognostic (2.80e-2)" "unprognostic (7.12e-3)" "unprognostic (3.05e-2)" "unprognostic (7.80e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.25e-5)" "unprognostic (3.50e-3)" "unprognostic (1.62e-1)" "unprognostic (5.57e-2)" "unprognostic (5.49e-3)" 5.0 5.0 11.9 5.5 12.7 6.7 5.3 16.7 15.6 7.6 10.6 6.0 6.4 6.3 4.6 5.1 5.7 4.2 4.0 11.6 11.9 7.0 5.9 4.4 7.7 12.8 12.4 7.3 5.1 5.1 5.9 6.4 12.7 5.8 5.6 4.9 4.5 5.0 5.6 5.9 6.1 3.6 11.7 7.8 5.8 3.3 12.2 9.8 6.6 4.7 7.0 5.9 5.8 14.4 7.9 6.9 15.5 10.5 11.3 8.4 26.6 5.7 7.4 11.8 9.2 14.3 11.2 22.5 9.0 3.6 9.5 11.3 8.7 11.0 5.4 18.1 7.0 10.2 11.4 10.5 10.0 9.4 7.1 4.6 10.3 16.0 25.7 3.1 8.6 28.6 17.5 7.4 5.0 13.3 27.3 8.7 39.6 19.5 7.9 36.2 12.6 12.3 6.1 14.6 14.5 11.8 11.3 8.7 18.2 20.1 6.7 11.1 4.9 8.3 6.2 7.2 8.2 11.6 14.6 13.3 8.0 14.6 7.5 1.6 7.0 2.9 11.5 11.8 17.2 8.1 11.8 11.5 8.1 8.0 12.7 12.2 1.4 8.8 9.1 6.5 13.4 8.6 11.9 12.7 16.7 15.6 11.6 11.9 12.8 12.4 12.7 11.7 12.2 14.4 10.0 0.0 5.6 17.0 12.1 6.9 10.7 8.1 6.2 15.6 6.7 8.8 3.2 1.5 6.9 7.3 2.1 40.2 8.8 16.5 3.9 6.5 0.9 3.2 5.1 7.6 7.8 6.7 4.0 5.3 14.3 7.5 16.8 3.2 10.8 8.4 5.7 4.3 10.0 5.0 7.0 15.1 12.2 4.0 10.2 1.6 10.8 5.6 7.2 8.4 8.2 12.0 10.3 11.6 12.7 3.8 16.4 12.0 7.5 9.5 12.9 12.2 8.6 20.1 13.1 8.7 7.6 10.5 11.2 5.2 5.4 22.2 13.9 9.5 13.5 8.0 MYO5B KIAA1119 ENSG00000167306 "Myosin VB" Q9ULV0 18 49822789-50195147 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 62.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 147.3;Inhibitory neurons: 90.5;Pancreatic endocrine cells: 106.6;Proximal enterocytes: 177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 65.5;HaCaT: 100.3;RH-30: 152.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040593, HPA040902, HPA069773" Enhanced Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA040593: AB_10795525, HPA040902: AB_10796230, HPA069773: AB_2686194" "unprognostic (2.51e-1)" "unprognostic (2.15e-2)" "unprognostic (2.12e-2)" "unprognostic (6.17e-3)" "unprognostic (2.14e-1)" "unprognostic (8.84e-3)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (4.13e-2)" "unprognostic (3.46e-1)" "prognostic unfavorable (2.26e-5)" "unprognostic (4.48e-2)" "prognostic favorable (1.45e-11)" "unprognostic (2.17e-3)" "unprognostic (1.50e-1)" "unprognostic (6.56e-2)" "unprognostic (3.28e-1)" 3.2 1.7 1.0 7.9 3.3 0.1 13.7 0.5 3.6 17.7 15.9 45.3 60.2 2.6 18.5 37.4 12.2 11.3 2.7 4.4 10.4 19.7 18.7 11.9 2.6 0.5 3.4 0.5 16.6 23.0 13.4 3.8 1.6 10.1 43.6 40.9 25.4 7.1 0.4 27.4 62.0 3.1 0.4 1.7 33.3 11.4 1.9 3.1 29.4 0.2 13.0 14.2 21.6 1.4 65.5 17.3 0.3 0.3 0.0 0.0 34.0 0.3 2.6 1.4 0.1 45.8 27.2 0.1 15.6 0.1 5.0 100.3 22.6 27.3 1.3 0.2 6.9 0.2 7.5 32.8 0.0 0.2 0.2 0.0 23.6 0.6 16.2 5.1 2.3 0.3 0.5 24.7 2.7 25.3 0.0 0.2 4.6 37.8 7.0 0.0 152.5 11.0 56.8 13.2 33.7 0.7 24.4 28.3 0.0 8.6 16.8 0.2 1.5 0.0 34.0 0.4 6.8 16.7 11.2 0.1 1.4 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.0 3.3 0.5 3.6 4.4 10.4 0.5 3.4 1.6 0.4 1.9 1.4 0.1 54.5 15.8 2.6 1.6 0.4 9.0 7.9 2.2 7.7 14.3 7.7 3.5 15.7 21.5 7.3 10.4 4.4 0.3 147.3 5.9 49.0 22.4 38.5 3.1 1.1 6.7 5.3 4.4 47.3 1.1 3.7 48.4 29.1 0.0 27.1 0.0 18.4 0.9 0.0 90.5 35.4 2.0 1.3 0.8 4.5 0.9 1.0 3.6 3.7 2.0 31.9 0.0 2.0 9.0 106.6 70.7 0.7 1.4 60.1 177.6 18.9 38.1 30.2 0.0 0.9 2.3 9.5 6.7 8.3 6.5 4.7 0.7 0.1 46.7 56.2 MYO9B CELIAC4 ENSG00000099331 "Myosin IXB" Q13459 19 17075781-17214537 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, GTPase activation, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 204.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037190, HPA042043" Approved Supported Cytosol NA NA 8400 "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "CAB037190: AB_477214, HPA042043: AB_10796897" "unprognostic (1.92e-1)" "unprognostic (1.79e-3)" "unprognostic (4.35e-2)" "unprognostic (6.63e-2)" "unprognostic (1.70e-1)" "unprognostic (1.18e-3)" "unprognostic (1.99e-2)" "unprognostic (1.31e-1)" "unprognostic (2.61e-2)" "prognostic unfavorable (2.61e-4)" "unprognostic (7.97e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (5.66e-6)" "unprognostic (1.97e-1)" "unprognostic (1.50e-1)" "unprognostic (2.36e-2)" "unprognostic (5.53e-2)" 41.0 43.6 38.6 52.6 53.3 98.9 32.3 46.7 56.7 44.9 32.6 45.3 17.5 44.5 12.4 32.9 30.3 20.6 37.2 39.2 46.8 26.9 39.1 78.2 60.3 60.3 53.5 22.5 26.4 6.9 25.6 21.3 56.4 46.1 14.8 40.2 28.3 13.5 12.7 29.6 62.0 17.4 45.8 158.1 36.2 64.2 61.3 33.1 26.3 5.1 35.9 48.1 41.5 77.6 55.6 25.4 33.2 38.9 23.7 24.7 95.7 51.6 26.4 31.8 27.8 20.5 27.7 51.4 28.0 45.5 28.4 34.3 14.2 25.2 23.9 92.4 29.4 62.1 31.2 19.7 30.2 49.1 95.8 22.8 13.0 44.1 17.1 19.5 33.6 22.5 25.9 34.1 22.2 23.1 66.8 90.8 25.0 17.8 55.4 72.3 24.9 14.8 12.6 46.4 11.3 25.3 32.1 25.2 67.8 17.8 25.0 50.7 65.7 58.9 26.2 92.1 44.1 48.7 33.6 32.8 58.2 63.4 75.0 4.5 3.2 6.1 2.7 4.0 1.7 2.8 2.0 2.2 1.9 2.4 1.3 1.9 12.2 2.6 2.6 3.7 3.5 2.0 38.6 53.3 46.7 56.7 39.2 46.8 60.3 53.5 56.4 45.8 61.3 77.6 20.5 9.6 23.0 17.0 47.2 19.6 70.3 9.9 10.8 11.9 15.3 13.7 10.3 11.5 10.7 5.5 204.3 17.3 43.5 34.2 1.9 7.8 6.0 14.5 45.3 28.9 7.2 19.8 36.0 7.7 24.8 22.2 35.7 28.1 22.1 24.1 23.2 15.8 74.8 8.4 26.0 14.8 8.2 68.5 91.0 13.6 12.5 103.6 44.4 49.6 65.4 11.1 66.9 40.7 112.8 12.4 18.2 17.0 37.2 40.7 10.9 3.2 9.6 98.8 6.6 16.1 24.6 8.5 14.3 10.5 18.0 14.4 47.0 18.9 17.1 46.9 NEUROG3 "Atoh5, bHLHa7, Math4B, ngn3" ENSG00000122859 "Neurogenin 3" Q9Y4Z2 10 69571698-69573422 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 5.4;intestine: 2.6" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 9.5;Enteroendocrine cells: 5.3" "Cancer enhanced" "Detected in some" "stomach cancer: 1.4" "Group enriched" "Detected in some" 20 "cerebral cortex: 4.5;hippocampal formation: 5.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "THP-1: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA039785 Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" Nucleoplasm "HPA039785: AB_10795114" "unprognostic (1.22e-2)" "unprognostic (7.33e-2)" "unprognostic (3.04e-2)" "unprognostic (2.42e-1)" "unprognostic (1.10e-1)" "unprognostic (1.65e-2)" "unprognostic (5.85e-5)" "unprognostic (4.58e-2)" "unprognostic (4.19e-1)" 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.6 2.6 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 4.5 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 NR1H4 "FXR, HRR-1, HRR1, RIP14" ENSG00000012504 "Nuclear receptor subfamily 1 group H member 4" Q96RI1 12 100473708-100564414 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Disease variant, FDA approved drug targets, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 39.1;liver: 120.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 92.9;Hepatocytes: 105.1;Proximal enterocytes: 331.0;Proximal tubular cells: 153.8" "Group enriched" "Detected in some" 11 "liver cancer: 18.7;renal cancer: 12.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 30 "Hep G2: 28.3;HHSteC: 14.1;RPTEC TERT1: 44.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA047699 Approved Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA047699: AB_10965320" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (6.68e-2)" "unprognostic (2.49e-1)" "unprognostic (1.60e-1)" "unprognostic (9.39e-2)" "unprognostic (2.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.16e-1)" "unprognostic (2.43e-1)" "unprognostic (3.77e-3)" 0.2 22.6 0.1 1.4 0.1 0.4 1.0 0.5 0.4 0.2 1.8 8.3 29.6 0.1 0.1 0.2 0.2 12.6 0.4 0.2 0.1 28.2 120.6 0.4 0.3 0.1 0.1 14.0 3.1 0.0 1.4 0.0 0.1 0.3 1.6 0.3 0.3 0.0 0.3 0.5 39.1 0.8 0.0 0.4 0.5 0.7 0.2 0.1 0.3 0.1 0.2 6.5 0.1 0.5 0.0 0.9 0.1 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 28.3 14.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.6 0.1 0.0 0.0 44.9 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 92.9 0.0 22.0 0.0 0.0 0.0 8.0 43.0 11.5 0.7 0.0 0.0 0.3 0.0 2.7 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.6 8.9 105.1 0.0 0.0 1.6 17.0 0.0 3.5 0.0 2.0 0.9 0.8 0.0 1.0 0.0 0.0 0.0 0.5 0.3 0.4 19.9 0.0 0.0 0.0 331.0 153.8 0.0 0.0 0.0 0.0 0.1 0.4 1.3 0.0 0.0 0.0 0.9 1.1 30.4 3.7 ODAPH "AI2A4, C4orf26, FLJ23657" ENSG00000174792 "Odontogenesis associated phosphoprotein" Q17RF5 4 75556048-75565871 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 1.7;placenta: 5.8" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 9.2;Syncytiotrophoblasts: 27.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.1;urothelial cancer: 0.7" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 33 "basophil: 10.7" "Lineage enriched" "Detected in single" 33 "granulocytes: 10.7" "Cell line enriched" "Detected in some" 6 "HDLM-2: 61.3" "Secreted in other tissues" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.13e-1)" "unprognostic (4.45e-3)" "unprognostic (3.78e-1)" "unprognostic (1.66e-1)" "unprognostic (6.12e-2)" "unprognostic (2.12e-2)" "unprognostic (1.75e-2)" "unprognostic (2.44e-1)" "unprognostic (3.87e-2)" "unprognostic (5.30e-2)" "unprognostic (3.43e-1)" "unprognostic (1.17e-7)" "unprognostic (8.31e-2)" "unprognostic (2.70e-2)" "unprognostic (8.40e-4)" "unprognostic (6.53e-3)" 0.1 0.1 0.7 0.2 0.7 0.3 0.1 0.9 1.7 0.1 0.5 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.6 0.1 0.1 0.1 0.2 0.8 0.8 0.1 0.0 0.0 0.4 5.8 0.9 0.1 0.2 0.5 0.1 0.1 0.9 0.3 0.2 0.0 0.6 0.1 0.1 0.4 0.7 0.1 0.0 0.0 0.3 0.1 0.1 1.5 0.9 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 1.3 0.5 0.1 0.2 0.0 0.1 0.1 0.0 0.2 0.3 61.3 0.0 0.2 0.2 0.3 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.7 0.1 0.0 0.1 0.0 2.8 0.0 2.1 0.3 0.1 0.0 0.1 2.6 0.1 0.9 9.6 0.1 0.1 0.6 0.2 0.0 10.7 0.1 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.1 0.7 0.7 0.9 1.7 0.6 0.6 0.8 0.8 0.9 0.6 0.7 1.5 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 1.8 0.0 1.9 0.1 0.0 0.0 3.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 9.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 27.0 0.1 0.1 0.0 0.0 PAX9 ENSG00000198807 "Paired box 9" P55771 14 36657568-36679362 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 81.0;lymphoid tissue: 20.5;parathyroid gland: 43.0;salivary gland: 51.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 45.3;Basal squamous epithelial cells: 174.8;Ionocytes: 40.7;Squamous epithelial cells: 172.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 12.3;HDLM-2: 58.3;PC-3: 18.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001572, CAB016239" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoli Nucleoplasm "CAB016239: AB_2159984, HPA001572: " "unprognostic (3.09e-1)" "prognostic favorable (5.38e-4)" "unprognostic (1.56e-2)" "unprognostic (2.80e-2)" "unprognostic (1.40e-2)" "unprognostic (1.43e-2)" "unprognostic (5.93e-3)" "unprognostic (2.71e-3)" "unprognostic (2.96e-1)" "unprognostic (5.58e-2)" "unprognostic (2.41e-2)" "unprognostic (9.44e-2)" "unprognostic (2.31e-4)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.17e-1)" 0.1 0.1 0.0 0.1 0.0 0.3 0.6 0.0 0.0 7.3 0.1 0.7 0.0 0.2 0.3 81.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.1 0.1 43.0 2.2 0.0 0.0 3.7 0.1 0.0 51.8 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 20.5 0.7 0.0 8.5 0.7 7.1 0.0 5.3 2.3 0.0 2.5 2.1 3.8 2.0 0.0 0.3 0.0 0.0 1.6 1.8 1.6 0.8 0.0 0.5 11.4 2.1 12.3 0.0 58.3 7.3 0.9 1.2 0.0 0.0 0.0 4.2 0.7 6.0 0.0 1.9 0.0 0.0 5.3 2.3 0.3 0.2 7.3 0.9 0.0 0.1 1.9 18.9 0.0 0.0 0.0 0.0 6.9 3.4 0.0 1.3 7.0 1.4 0.9 5.1 0.0 0.0 0.0 0.6 2.2 1.0 0.0 0.1 4.4 0.7 0.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 8.4 45.3 174.8 0.0 1.6 1.3 0.4 0.0 25.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.6 0.0 0.4 0.0 0.2 0.2 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 40.7 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 20.9 0.0 0.0 26.8 0.0 0.0 0.1 2.0 2.4 0.9 172.0 0.3 0.1 0.1 0.0 0.6 12.1 PDX1 "IDX-1, IPF1, MODY4, PDX-1, STF-1" ENSG00000139515 "Pancreatic and duodenal homeobox 1" P52945 13 27920000-27926313 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 41.8;pancreas: 13.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 15.7;Ductal cells: 13.3;Enteroendocrine cells: 13.8;Exocrine glandular cells: 9.8;Gastric mucus-secreting cells: 4.6" "Group enriched" "Detected in many" 4 "colorectal cancer: 8.4;pancreatic cancer: 8.6;stomach cancer: 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 4.0;HEK 293: 2.3;HeLa: 5.9;OE19: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025873, HPA059146" Enhanced Supported Nucleoplasm NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "CAB025873: , HPA059146: AB_2683927" "unprognostic (2.79e-2)" "unprognostic (2.22e-1)" "unprognostic (1.92e-1)" "unprognostic (2.65e-1)" "unprognostic (6.84e-2)" "unprognostic (3.89e-2)" "unprognostic (6.75e-3)" "unprognostic (7.10e-3)" "unprognostic (3.83e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 41.8 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 13.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 5.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 4.0 2.3 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 15.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 13.3 0.0 0.0 0.0 0.0 13.8 0.0 0.0 9.8 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 PERCC1 ENSG00000284395 "Proline and glutamate rich with coiled coil 1" A0A1W2PR82 16 1431078-1434441 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "prostate: 1.8;stomach 1: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 56 "SCLC-21H: 33.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 4.0" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 7: SCLC-21H - Neuronal signaling" 0.1 0.0 0.2 0.1 0.3 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.6 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 33.3 0.4 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G4A "cPLA2-alpha, PLA2G4" ENSG00000116711 "Phospholipase A2 group IVA" P47712 1 186828949-186988981 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Glycerol metabolism, Leukotriene biosynthesis, Lipid biosynthesis, Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 87.2;seminal vesicle: 48.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 33.4;Glandular and luminal cells: 28.1;Microglial cells: 115.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 6.8;eosinophil: 7.8;intermediate monocyte: 8.4;myeloid DC: 7.7;non-classical monocyte: 4.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 7 "dendritic cells: 7.7;granulocytes: 7.8;monocytes: 8.4" "Cell line enhanced" "Detected in many" "HeLa: 52.4;OE19: 84.4;RPMI-8226: 73.4;U-2197: 66.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010050, HPA050062, HPA054206" Approved Supported Vesicles,Cytosol NA NA 35000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Cytosol Vesicles "CAB010050: AB_631312, HPA050062: AB_2681002, HPA054206: AB_2682417" "prognostic favorable (9.07e-4)" "unprognostic (1.18e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.85e-4)" "unprognostic (5.55e-2)" "unprognostic (1.51e-3)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (2.63e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (2.96e-2)" "unprognostic (8.07e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (4.26e-2)" 9.9 12.7 2.4 6.3 3.4 4.8 6.5 2.8 3.7 14.5 3.2 11.9 11.1 10.2 11.7 7.5 24.9 6.2 6.3 2.4 3.3 10.8 2.1 5.9 5.3 4.4 3.5 6.4 7.6 87.2 2.0 5.8 4.0 8.8 8.1 0.8 6.3 48.3 0.5 9.5 8.2 10.5 4.1 6.6 5.3 2.8 3.1 1.5 2.6 2.1 2.9 29.1 8.4 3.9 0.0 39.7 0.2 0.0 23.8 9.5 0.0 1.5 15.1 1.8 3.2 0.3 15.5 0.0 0.0 0.0 6.8 2.8 24.6 7.4 0.8 12.5 0.6 7.6 52.4 0.0 14.7 11.1 3.8 5.4 5.0 19.5 4.0 2.4 16.5 3.4 16.7 5.9 0.0 0.0 0.0 0.0 2.1 84.4 5.1 0.0 0.0 73.4 0.1 5.4 0.2 0.0 5.9 2.0 7.3 0.7 0.8 15.0 3.3 14.3 1.9 66.3 3.2 2.3 0.0 0.0 5.3 32.4 20.7 0.2 6.8 7.8 0.0 8.4 0.2 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.6 1.1 4.0 3.1 0.0 1.7 2.4 3.4 2.8 3.7 2.4 3.3 4.4 3.5 4.0 4.1 3.1 3.9 0.6 0.0 1.1 0.3 0.2 21.4 4.3 4.6 10.2 0.2 2.9 2.9 2.3 0.0 4.9 0.0 0.0 0.1 3.2 1.6 1.9 2.1 0.9 33.4 1.7 6.6 1.2 3.0 8.1 0.0 0.1 11.2 7.1 28.1 10.8 3.3 1.1 0.2 6.6 0.0 5.8 2.6 2.0 7.9 8.3 1.3 10.5 11.5 5.4 115.2 3.7 0.0 1.0 2.0 0.4 1.7 7.3 14.7 0.0 2.3 2.0 0.3 2.3 0.5 0.0 1.2 5.0 0.6 0.3 5.2 8.9 0.0 1.0 1.2 4.8 13.4 PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 436.2" "Group enriched" "Detected in many" 4 "Adipocytes: 439.2;Endothelial cells: 344.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Cell line enriched" "Detected in some" 27 "EFO-21: 549.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" 283.0 51.1 2.7 54.6 3.1 1.7 210.5 2.9 4.2 102.7 18.2 95.7 86.7 90.0 5.1 48.9 83.3 139.2 92.5 3.3 3.1 153.0 6.9 31.0 50.5 3.7 3.5 16.7 96.1 98.6 64.3 48.8 3.6 68.4 22.3 0.0 77.9 38.0 32.7 58.9 103.3 50.5 3.6 166.7 116.6 4.4 3.5 18.9 436.2 12.9 16.2 104.4 80.8 4.1 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 549.1 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 9.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.1 20.0 0.0 2.3 0.1 0.3 0.5 2.2 2.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.7 35.2 0.0 0.6 2.7 3.1 2.9 4.2 3.3 3.1 3.7 3.5 3.6 3.6 3.5 4.1 439.2 6.4 0.0 0.3 0.7 22.9 1.0 0.0 8.0 0.0 2.7 3.3 3.7 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 1.7 3.6 0.4 0.3 344.9 0.0 0.4 0.4 2.5 0.1 48.9 0.0 0.3 0.0 0.4 79.6 0.2 1.8 0.0 0.3 0.0 0.0 3.5 28.8 0.8 0.0 5.5 23.2 6.5 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 7.6 1.5 0.0 0.0 0.0 0.1 0.0 1.4 6.1 0.5 0.7 2.9 16.8 0.1 1.4 0.7 0.0 2.3 PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923792-43964488 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 31.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 35.9;Cone photoreceptor cells: 18.8;Hepatocytes: 42.3;Rod photoreceptor cells: 37.3" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 16.7;LHCN-M2: 19.3" "Region enhanced" "Detected in many" "cerebellum: 12.2" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoli "Mitochondria, Cytosol" "HPA058058: AB_2683590" "unprognostic (4.74e-3)" "unprognostic (4.52e-2)" "unprognostic (1.76e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-3)" "unprognostic (2.52e-3)" "unprognostic (5.91e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" 2.6 0.2 0.6 0.5 0.8 0.1 1.6 0.1 1.2 0.6 5.9 0.1 0.8 0.3 0.1 0.2 0.9 0.4 0.2 1.2 0.7 4.5 31.0 0.8 0.3 1.7 1.8 0.3 0.0 0.2 0.0 0.3 2.0 0.0 0.1 6.4 0.7 0.0 1.7 5.8 0.5 0.0 0.2 0.4 0.2 0.4 1.3 0.1 0.1 0.1 0.2 0.0 0.3 0.6 5.1 1.6 16.7 6.8 4.6 5.2 0.5 3.1 1.8 4.1 8.8 5.0 9.0 0.0 2.5 5.2 2.4 4.3 10.6 5.0 3.4 0.0 0.9 0.3 4.5 9.4 7.5 0.0 0.3 6.0 3.8 13.2 0.6 7.0 0.5 0.2 0.0 0.0 19.3 0.7 0.3 0.0 11.5 0.6 0.0 0.1 8.9 0.2 1.7 0.2 1.5 0.1 3.4 1.4 4.8 2.9 5.3 5.8 0.6 1.6 4.9 0.1 0.1 0.1 0.0 0.0 14.3 0.1 6.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.8 0.1 1.2 1.2 0.7 1.7 1.8 2.0 0.2 1.3 0.6 0.4 0.0 0.0 4.2 0.2 0.4 0.5 2.4 0.0 35.9 0.5 0.1 1.3 10.0 1.4 0.0 18.8 0.0 0.2 0.2 0.0 0.4 0.0 1.5 0.5 0.4 1.8 0.0 1.9 0.0 0.1 0.5 0.0 3.6 0.0 1.9 0.7 42.3 0.7 0.0 1.2 0.8 0.0 2.8 0.3 0.3 0.3 0.9 1.8 0.0 0.0 1.1 0.0 0.0 0.8 2.6 0.0 0.7 0.0 0.7 0.4 5.0 0.1 37.3 0.0 1.0 0.8 0.6 0.6 0.0 0.1 0.0 0.2 1.6 0.4 0.4 PRSS1 TRY1 ENSG00000204983 "Serine protease 1" P07477 7 142749468-142753076 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1923 "pancreas: 341429.7" "Cell type enriched" "Detected in some" 28 "Exocrine glandular cells: 57138.3" "Cancer enriched" "Detected in many" 224 "pancreatic cancer: 1920.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "OE19: 10.6;RPMI-8226: 4.5;U-2 OS: 2.8" "CAB025487, CAB025538, HPA062452, HPA063471" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 100000000000 "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Endoplasmic reticulum" "CAB025487: , CAB025538: , HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.55e-5)" "unprognostic (5.28e-1)" "unprognostic (7.58e-2)" "prognostic unfavorable (6.41e-6)" "unprognostic (8.26e-2)" "prognostic favorable (7.05e-4)" "unprognostic (1.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-1)" "prognostic favorable (4.91e-4)" "unprognostic (3.12e-1)" 45.2 9.9 0.0 4.7 0.0 0.0 25.7 0.0 0.0 19.9 0.0 11.2 54.5 8.9 0.8 15.2 5.6 0.0 51.0 0.0 0.0 9.6 29.7 6.4 6.5 0.0 0.0 177.5 341429.7 0.1 10.3 13.9 0.0 15.2 0.0 0.0 44.2 4.2 8.9 12.1 12.7 0.0 0.0 13.4 77.1 6.9 0.0 0.0 6.4 0.0 0.0 4.7 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 100.7 0.0 0.1 0.0 3.6 0.0 0.0 0.0 57138.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 119.4 0.6 0.0 0.0 0.0 1985.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.2 0.2 PRSS2 TRY2 ENSG00000275896 "Serine protease 2" P07478 7 142760398-142774564 "Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 452 "pancreas: 239420.0" "Cell type enriched" "Detected in some" 11 "Exocrine glandular cells: 108258.7" "Cancer enriched" "Detected in many" 72 "pancreatic cancer: 3463.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "basophil: 4.1;T-reg: 2.9" "Group enriched" "Detected in many" 8 "granulocytes: 4.1;T-cells: 2.9" "Cell line enhanced" "Detected in some" "OE19: 21.0;RPMI-8226: 67.5;U-2 OS: 15.2" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 890000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "prognostic favorable (2.32e-4)" "unprognostic (3.80e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-3)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-3)" "unprognostic (1.48e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.58e-2)" "unprognostic (3.50e-1)" "unprognostic (5.36e-3)" "unprognostic (1.18e-1)" 65.1 12.5 0.1 0.2 0.1 3.2 25.4 0.0 0.1 27.6 0.0 12.6 358.5 11.4 0.0 18.2 9.6 0.1 25.0 0.0 0.0 9.4 32.2 8.2 1.3 0.0 0.0 64.9 239420.0 0.0 13.4 8.1 0.0 17.2 0.0 0.0 25.4 0.9 10.1 11.3 529.2 0.1 0.0 16.9 54.7 8.6 0.0 0.9 8.3 0.0 0.0 7.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.4 4.4 0.5 0.0 0.0 0.0 1.9 0.0 21.0 0.0 0.0 0.0 67.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.9 3.8 0.0 2.9 0.6 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.9 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 378.7 0.0 0.4 0.1 11.4 0.0 0.0 0.0 108258.7 0.0 0.3 4.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 348.9 0.0 0.0 0.0 0.0 9565.7 8.9 0.0 0.1 0.0 60.0 0.1 0.0 0.0 0.0 0.0 36.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 85.4 0.2 PTH1R "PTHR, PTHR1" ENSG00000160801 "Parathyroid hormone 1 receptor" Q03431 3 46877721-46903799 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "kidney: 586.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 95.9;Extravillous trophoblasts: 60.8;Proximal tubular cells: 324.8;Sertoli cells: 138.1" "Group enriched" "Detected in many" 4 "renal cancer: 18.8;testis cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "RPTEC TERT1: 116.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075879 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA075879: " "unprognostic (1.26e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-5)" "unprognostic (7.46e-2)" "unprognostic (3.46e-1)" "unprognostic (5.02e-2)" "unprognostic (3.84e-3)" "unprognostic (5.47e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (7.51e-2)" "unprognostic (8.44e-2)" "prognostic favorable (6.79e-6)" "unprognostic (4.22e-3)" "unprognostic (1.50e-1)" "unprognostic (1.35e-4)" "unprognostic (6.62e-3)" 32.5 72.2 45.0 1.1 43.8 0.0 20.2 45.7 60.8 43.8 38.0 10.3 1.2 19.1 2.7 3.7 20.3 3.5 33.0 42.6 43.5 586.8 84.6 25.6 2.4 46.5 44.9 22.2 7.6 1.2 5.9 16.0 46.7 12.4 0.6 0.7 2.7 3.5 7.7 9.8 9.6 2.6 44.5 54.4 7.6 10.3 46.2 0.4 6.5 2.2 0.4 12.3 20.3 43.3 0.0 0.2 0.2 0.2 15.9 1.9 0.2 0.4 0.2 0.3 0.2 0.4 0.0 0.0 1.6 0.1 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.0 15.5 0.0 0.1 0.0 0.2 0.1 0.0 0.0 2.6 0.1 0.1 0.0 0.3 2.1 0.0 0.1 0.1 5.3 0.0 116.9 0.0 0.2 0.7 0.0 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.0 43.8 45.7 60.8 42.6 43.5 46.5 44.9 46.7 44.5 46.2 43.3 4.6 0.0 0.0 17.3 2.5 1.3 0.1 0.0 0.6 1.5 2.9 0.4 5.0 2.8 0.0 33.1 0.0 0.6 0.1 0.0 95.9 0.0 11.6 0.6 20.5 4.1 0.0 8.0 1.6 0.5 60.8 9.6 0.0 0.6 0.0 0.1 17.2 0.7 2.0 1.7 2.8 0.0 0.0 1.3 2.8 32.5 5.9 2.1 0.0 1.9 0.0 3.2 0.0 1.0 0.3 0.3 0.0 2.2 0.0 0.0 0.0 324.8 0.0 1.7 138.1 6.5 21.7 0.9 2.7 0.0 0.9 0.8 2.0 0.3 0.0 0.1 RELT "FLJ14993, TNFRSF19L" ENSG00000054967 "RELT TNF receptor" Q969Z4 11 73376399-73397474 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Receptor "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 154.7" "Cell type enhanced" "Detected in many" "Langerhans cells: 43.9;Macrophages: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062824, HPA071518" Supported Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA062824: AB_2684875, HPA071518: AB_2686408" "unprognostic (3.49e-1)" "unprognostic (2.43e-1)" "unprognostic (2.25e-1)" "unprognostic (1.67e-2)" "unprognostic (1.80e-3)" "unprognostic (9.92e-3)" "unprognostic (1.67e-3)" "unprognostic (1.17e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-1)" "unprognostic (8.42e-2)" "unprognostic (4.13e-2)" "prognostic unfavorable (4.07e-11)" "unprognostic (1.64e-1)" "unprognostic (3.07e-3)" "unprognostic (2.01e-2)" "unprognostic (1.69e-1)" 4.9 2.2 3.4 12.9 6.5 154.7 2.5 6.7 7.7 1.4 0.4 2.3 2.3 1.4 0.5 3.9 1.9 4.5 6.2 3.6 7.0 3.7 2.1 10.9 11.9 8.9 6.8 1.8 0.8 1.1 3.5 4.6 8.1 2.1 1.4 2.2 1.9 0.4 24.3 3.2 7.1 2.6 7.0 20.8 2.2 3.2 6.9 4.6 2.2 6.4 6.9 4.8 2.3 12.6 9.1 8.9 7.0 6.8 0.8 1.0 7.5 9.6 6.2 11.1 6.7 8.5 3.9 16.4 30.9 6.4 8.8 13.1 4.4 4.7 4.3 9.9 8.3 15.4 12.4 3.1 1.8 15.6 26.3 1.1 2.0 11.9 3.5 2.6 4.1 8.4 11.8 21.0 3.1 8.5 11.5 16.5 6.1 6.9 11.0 21.9 11.7 14.2 2.3 3.9 8.9 8.5 8.3 7.5 10.0 1.7 4.1 13.9 5.4 13.8 9.7 23.1 17.6 7.5 6.1 18.2 8.5 15.5 14.8 0.7 12.5 22.2 0.9 25.4 2.0 7.6 1.0 1.7 11.8 5.8 1.3 0.6 19.9 0.4 35.3 11.7 0.5 6.3 3.4 6.5 6.7 7.7 3.6 7.0 8.9 6.8 8.1 7.0 6.9 12.6 5.7 6.4 2.2 3.6 24.2 26.5 15.4 2.8 2.8 3.5 6.1 5.5 2.7 1.5 3.4 0.0 12.5 1.6 33.0 4.7 0.0 3.6 0.9 5.4 5.2 7.2 3.5 5.7 3.1 0.9 10.7 10.1 11.2 10.8 24.8 6.8 1.8 0.2 23.0 30.3 4.5 2.8 6.1 24.2 43.9 1.2 0.0 43.9 5.4 2.8 32.8 8.9 3.1 1.5 4.8 6.7 2.4 0.0 19.2 9.9 1.0 0.5 1.4 2.8 6.6 7.2 14.5 11.7 10.5 4.6 18.3 21.1 16.1 0.6 3.1 17.8 REST "DFNA27, NRSF, XBR" ENSG00000084093 "RE1 silencing transcription factor" Q13127 4 56907876-56966808 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006079, CAB068222" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "CAB068222: AB_2665651, HPA006079: AB_1079801" "unprognostic (7.49e-3)" "unprognostic (3.36e-2)" "unprognostic (2.50e-2)" "unprognostic (2.03e-2)" "unprognostic (1.86e-1)" "unprognostic (1.39e-1)" "unprognostic (7.47e-3)" "unprognostic (2.30e-1)" "unprognostic (4.65e-2)" "unprognostic (1.70e-2)" "unprognostic (4.32e-3)" "unprognostic (1.73e-1)" "prognostic favorable (9.50e-5)" "unprognostic (1.49e-1)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (4.79e-2)" 6.9 5.5 5.7 9.4 6.5 24.8 9.8 6.3 7.5 8.8 9.4 6.9 6.4 9.3 8.9 8.2 7.8 7.9 7.6 5.0 5.2 10.9 11.5 8.0 13.4 8.0 6.6 11.2 7.7 13.8 0.5 9.9 7.8 10.0 7.0 7.5 7.8 8.1 5.2 8.9 6.3 8.0 6.6 10.7 8.2 12.3 6.8 18.1 10.9 6.5 13.6 8.7 2.1 7.4 10.8 13.0 17.4 18.2 13.2 16.0 22.7 15.6 13.8 16.0 14.7 11.5 16.5 24.5 23.5 16.8 10.7 9.8 13.2 16.3 24.4 12.6 8.1 22.0 9.4 12.5 16.2 29.0 13.5 16.5 14.6 15.1 16.0 20.5 20.1 19.0 14.3 26.3 19.0 17.3 31.5 21.3 15.2 12.3 8.9 30.0 14.5 8.1 19.0 18.3 0.3 8.1 17.8 18.8 14.6 24.8 19.3 20.3 28.7 20.4 18.1 12.4 14.2 10.8 7.8 15.1 13.2 16.7 10.8 7.4 2.5 7.2 6.2 3.9 6.2 11.6 6.9 5.9 5.2 21.1 10.8 4.4 2.8 6.1 7.9 6.0 9.4 2.5 5.7 6.5 6.3 7.5 5.0 5.2 8.0 6.6 7.8 6.6 6.8 7.4 38.1 70.5 60.2 18.6 51.1 57.1 51.9 33.3 99.6 1.6 42.6 35.2 50.2 42.9 43.3 29.5 81.3 58.0 65.2 21.4 23.5 58.4 9.7 67.3 64.3 50.5 3.6 54.7 0.1 38.2 57.1 40.8 23.9 63.4 51.4 56.3 47.2 31.0 32.2 0.0 0.2 23.5 44.7 36.2 37.9 11.9 39.4 44.0 21.4 12.2 78.0 45.1 71.1 11.1 21.1 45.8 29.0 36.9 44.3 44.3 22.1 24.4 43.3 36.1 32.9 56.5 56.0 58.3 53.8 55.0 45.7 66.4 66.6 62.3 26.1 48.7 SGO1 "NY-BR-85, SGOL1" ENSG00000129810 "Shugoshin 1" Q5FBB7 3 20160593-20186206 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.7;lymphoid tissue: 13.0;testis: 6.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 16.5;Extravillous trophoblasts: 42.6;Granulosa cells: 20.3;Hofbauer cells: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "basophil: 10.0;memory B-cell: 8.8;naive B-cell: 8.9;plasmacytoid DC: 4.1;T-reg: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035501, HPA069302, HPA069857" Enhanced Enhanced Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Kinetochore, Cytosol" "HPA035501: AB_2732469, HPA069302: , HPA069857: AB_2686214" "unprognostic (6.87e-3)" "unprognostic (5.01e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-3)" "unprognostic (2.51e-2)" "unprognostic (4.10e-2)" "unprognostic (2.55e-6)" "unprognostic (9.49e-3)" "unprognostic (2.45e-2)" "unprognostic (3.69e-2)" "unprognostic (1.65e-4)" "unprognostic (1.52e-2)" "unprognostic (0.00e+0)" "unprognostic (2.29e-2)" "unprognostic (4.95e-2)" "unprognostic (4.14e-1)" "unprognostic (1.64e-1)" 0.3 0.1 0.3 3.3 0.7 8.7 0.5 0.9 0.5 0.4 0.0 2.1 2.3 0.4 0.0 1.9 0.1 0.4 0.1 0.3 0.4 0.3 0.6 0.3 6.2 0.8 0.6 0.2 0.1 0.2 0.0 1.7 0.6 0.2 2.8 0.1 0.4 0.1 0.1 1.1 2.5 1.0 0.3 1.4 1.5 6.7 0.6 13.0 0.2 0.0 6.6 0.9 0.7 1.2 20.3 23.9 29.9 18.5 1.4 2.6 20.2 21.3 10.1 31.2 33.6 16.5 24.0 30.7 10.6 8.6 21.2 11.4 28.7 11.3 37.6 40.9 19.6 34.6 15.6 12.8 0.2 32.0 28.8 0.3 0.9 33.3 13.1 4.0 18.5 34.9 31.3 52.2 24.6 19.4 52.4 15.4 30.0 20.3 17.0 31.8 38.4 17.7 7.5 14.9 14.2 15.4 23.6 27.2 13.1 22.7 18.2 21.3 4.7 22.5 27.3 20.5 43.3 22.8 57.4 35.2 12.5 31.1 35.0 10.0 0.1 1.4 0.2 0.2 0.1 8.8 0.6 0.7 0.3 8.9 0.2 0.3 1.4 0.3 0.2 4.1 2.6 0.6 0.3 0.7 0.9 0.5 0.3 0.4 0.8 0.6 0.6 0.3 0.6 1.2 0.1 0.0 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 2.0 3.4 0.0 0.0 0.0 1.8 0.0 16.5 1.5 0.0 0.0 1.1 0.0 2.3 1.6 1.2 0.0 0.0 0.0 1.8 42.6 3.3 0.0 2.9 1.3 20.3 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 4.9 1.0 4.3 0.0 0.0 SH3BP2 "CRBM, RES4-23" ENSG00000087266 "SH3 domain binding protein 2" P78314 4 2793071-2841098 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036789, HPA036790" Approved Approved "Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA036789: , HPA036790: AB_10671712" "unprognostic (7.86e-2)" "unprognostic (3.45e-1)" "unprognostic (9.83e-2)" "prognostic unfavorable (5.42e-6)" "prognostic unfavorable (9.52e-4)" "prognostic favorable (1.57e-5)" "unprognostic (6.58e-2)" "unprognostic (3.16e-2)" "unprognostic (3.17e-2)" "unprognostic (6.41e-3)" "unprognostic (3.35e-2)" "unprognostic (3.30e-2)" "unprognostic (3.24e-3)" "unprognostic (1.78e-2)" "unprognostic (5.32e-1)" "unprognostic (1.78e-1)" "prognostic favorable (2.67e-4)" 15.3 6.8 17.2 30.0 20.6 48.2 7.9 20.1 16.6 7.0 6.8 12.3 11.4 6.8 9.8 7.1 8.9 8.7 6.7 14.4 22.3 13.1 12.1 17.0 23.2 34.0 30.5 5.8 9.6 4.8 5.0 12.8 25.2 5.3 9.1 5.2 10.4 8.3 16.9 39.7 16.0 10.5 21.5 43.9 16.7 5.2 36.1 8.4 4.7 4.8 13.3 12.3 9.7 14.8 11.2 5.2 7.4 8.7 4.6 14.6 7.2 16.8 13.0 11.1 10.9 6.9 31.6 18.0 20.5 14.2 9.7 5.6 0.3 10.5 7.5 12.2 6.8 41.4 15.2 6.1 17.1 15.4 29.1 27.7 10.5 7.1 5.9 11.8 25.7 13.7 2.5 37.2 15.0 9.6 2.7 24.3 13.3 21.6 13.3 0.6 7.4 9.9 20.1 16.1 25.4 16.4 12.8 10.7 10.3 6.8 15.7 30.8 35.4 12.1 8.9 4.2 13.8 19.5 10.6 4.3 14.1 40.2 14.4 4.1 21.0 13.6 13.8 36.5 8.2 3.0 3.8 8.8 15.9 6.9 1.9 5.0 33.8 8.3 44.6 6.7 6.9 12.1 17.2 20.6 20.1 16.6 14.4 22.3 34.0 30.5 25.2 21.5 36.1 14.8 27.6 3.2 5.8 40.5 19.5 38.1 10.0 35.3 8.6 0.8 19.8 10.0 8.3 7.2 25.3 40.5 0.0 1.3 43.7 42.5 3.9 6.3 8.5 9.7 11.0 31.3 10.2 14.9 0.4 22.0 1.2 11.3 18.3 22.0 9.5 11.6 33.9 59.0 49.3 0.0 2.7 14.2 30.5 81.5 63.3 10.8 13.7 71.9 19.6 18.7 48.9 23.7 57.7 2.5 0.5 25.3 27.1 10.1 18.1 16.1 23.7 43.7 12.3 6.4 39.5 5.2 16.0 1.9 3.7 18.6 83.4 4.2 22.0 25.5 15.4 20.1 SLC10A2 "ASBT, ISBT" ENSG00000125255 "Solute carrier family 10 member 2" Q12908 13 103043998-103066417 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 80.8" "Cell type enriched" "Detected in some" 29 "Proximal enterocytes: 371.2" "Cancer enriched" "Detected in single" 11 "renal cancer: 4.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA004795 Approved NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 45: Enterocytes - Digestion" "HPA004795: AB_1856953" "unprognostic (2.82e-2)" "prognostic favorable (5.78e-5)" "unprognostic (1.64e-2)" "unprognostic (1.29e-1)" 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.3 0.2 0.0 0.0 0.4 23.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 16.9 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 80.8 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.2 0.5 0.3 0.5 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 371.2 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.1 SLC24A4 NCKX4 ENSG00000140090 "Solute carrier family 24 member 4" Q8NFF2 14 92322581-92501481 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Olfaction, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "choroid plexus: 92.6" "Group enriched" "Detected in some" 4 "Bipolar cells: 251.6;Cone photoreceptor cells: 200.1" "Group enriched" "Detected in some" 5 "glioma: 0.5;melanoma: 0.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 11.1;intermediate monocyte: 14.7;non-classical monocyte: 11.6" "Lineage enriched" "Detected in many" 5 "monocytes: 14.7" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063206 Approved "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA063206: " "unprognostic (1.53e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-1)" "unprognostic (1.18e-1)" "unprognostic (1.06e-1)" "unprognostic (3.43e-3)" "unprognostic (1.34e-1)" "unprognostic (2.04e-3)" "unprognostic (3.40e-2)" "unprognostic (1.32e-1)" "unprognostic (2.48e-3)" "unprognostic (3.21e-1)" "unprognostic (1.48e-3)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-2)" "unprognostic (1.58e-2)" 0.5 0.2 7.1 1.4 10.3 3.5 0.1 17.5 8.1 0.2 92.6 0.2 0.2 0.1 0.1 0.2 0.2 0.6 0.2 7.2 5.3 0.0 0.1 0.8 1.2 22.7 14.1 0.2 0.1 0.0 1.4 0.3 19.1 0.2 0.2 12.3 0.1 0.3 0.8 0.1 0.3 0.4 14.7 2.7 0.1 1.1 16.5 0.4 0.1 1.0 0.4 0.3 0.2 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.1 0.0 0.0 14.7 0.2 0.0 0.0 0.0 3.0 0.1 0.0 0.0 1.5 0.1 11.6 0.5 0.0 2.7 7.1 10.3 17.5 8.1 7.2 5.3 22.7 14.1 19.1 14.7 16.5 12.9 0.8 0.0 1.9 47.0 0.4 0.0 0.1 0.0 0.0 251.6 0.3 0.1 1.8 0.0 0.0 0.0 200.1 0.0 0.1 0.0 0.0 0.0 4.0 0.5 0.1 0.9 0.0 0.8 19.9 0.0 0.1 0.5 0.0 0.8 0.0 0.0 1.1 0.0 4.0 0.0 28.5 0.0 0.0 22.2 1.8 5.6 0.3 16.6 0.0 2.8 44.3 4.1 1.0 10.1 1.3 0.1 0.0 0.4 0.1 0.2 0.0 0.2 0.7 10.6 0.0 9.9 0.2 0.1 1.6 0.0 0.0 0.3 0.3 0.0 0.0 0.1 SLC26A3 "CLD, DRA" ENSG00000091138 "Solute carrier family 26 member 3" P40879 7 107765467-107803225 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 1120.4" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 2328.4" "Cancer enriched" "Detected in many" 14 "colorectal cancer: 52.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036055 Approved NA NA "Cluster 37: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036055: AB_10602401" "unprognostic (1.26e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.69e-1)" "unprognostic (4.02e-1)" "unprognostic (4.09e-2)" "unprognostic (3.05e-3)" "unprognostic (6.31e-2)" "unprognostic (1.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-2)" "unprognostic (8.85e-2)" "unprognostic (8.01e-2)" "unprognostic (5.52e-2)" "unprognostic (2.54e-2)" "unprognostic (3.58e-3)" 1.1 0.0 0.0 19.7 0.0 0.0 59.5 0.2 0.1 0.3 0.0 1120.4 576.9 0.9 15.3 0.5 0.8 17.8 0.0 0.0 0.0 0.8 0.5 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.1 878.8 0.1 0.0 129.9 0.0 0.1 118.5 15.0 0.0 0.0 1.3 0.9 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 165.9 4.2 0.0 0.3 0.0 0.0 0.0 51.4 41.7 0.3 34.3 0.0 0.0 0.0 0.0 0.0 2328.4 0.0 0.0 6.4 1.8 0.1 0.3 14.3 0.0 110.2 0.0 0.0 0.1 0.0 0.2 26.7 0.2 0.0 0.1 0.0 0.0 114.3 32.5 0.0 0.0 0.0 0.6 0.3 0.1 0.0 89.9 0.0 0.0 0.0 101.6 182.1 0.0 503.4 0.0 0.0 0.3 388.9 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.2 0.0 86.0 0.1 SLC9A3 NHE3 ENSG00000066230 "Solute carrier family 9 member A3" P48764 5 470456-524449 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 45.4;intestine: 94.3;kidney: 62.5;stomach 1: 50.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Collecting duct cells: 16.5;Proximal tubular cells: 40.7" "Cancer enhanced" "Detected in many" "stomach cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 37.8" "Region enriched" "Detected in single" 14 "cerebellum: 4.1" "Low region specificity" "Detected in many" "HPA036493, HPA036669" Enhanced Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA036493: AB_10673353, HPA036669: AB_10670843" "unprognostic (1.27e-1)" "unprognostic (4.88e-1)" "unprognostic (9.35e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (3.35e-1)" "unprognostic (2.51e-1)" "unprognostic (9.40e-2)" "prognostic unfavorable (8.49e-4)" "unprognostic (5.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.69e-2)" "unprognostic (3.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (1.24e-2)" "unprognostic (1.32e-1)" 2.9 4.4 3.0 10.4 2.5 1.9 3.1 6.1 5.0 3.8 1.7 94.3 46.0 2.9 4.0 8.7 4.9 45.4 3.2 4.7 2.5 62.5 2.4 2.8 3.8 3.8 2.3 4.3 6.7 6.2 0.7 2.1 3.7 7.3 10.8 1.7 9.9 3.8 6.2 19.0 68.1 3.3 1.3 3.7 50.1 5.8 3.4 3.5 4.9 3.9 3.4 2.5 2.5 2.6 6.7 5.1 10.4 10.5 2.5 3.0 7.8 5.3 3.9 8.0 5.0 11.0 7.4 14.0 7.5 3.0 5.5 10.0 6.1 4.0 3.9 37.8 10.7 6.7 23.4 5.4 3.9 5.5 8.2 4.2 8.1 3.5 5.4 3.9 2.4 6.3 9.6 7.5 2.9 9.0 6.0 24.3 4.0 17.8 8.3 8.6 9.3 8.3 2.8 4.8 11.5 5.0 19.0 5.3 4.2 4.5 12.3 4.2 2.9 8.0 7.2 5.3 3.9 12.4 5.8 8.5 5.2 21.2 5.6 0.0 0.7 0.1 2.6 0.3 2.2 0.9 3.3 2.4 0.9 1.0 3.9 3.1 0.1 2.4 0.2 1.2 2.7 1.8 3.0 2.5 6.1 5.0 4.7 2.5 3.8 2.3 3.7 1.3 3.4 2.6 3.8 16.0 5.8 0.0 1.5 0.0 0.0 0.0 0.0 0.0 7.3 8.9 0.7 0.0 5.6 16.5 0.0 0.0 3.4 0.7 5.9 9.0 0.0 3.8 3.6 2.3 0.0 0.0 0.3 8.8 0.0 2.2 0.0 2.6 2.5 5.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 4.6 0.0 0.0 0.0 0.1 7.7 0.0 0.0 0.7 0.0 1.1 40.7 2.9 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 2.3 5.4 0.0 0.0 SLCO2A1 "MATR1, OATP2A1, PGT, SLC21A2" ENSG00000174640 "Solute carrier organic anion transporter family member 2A1" Q92959 3 133932701-134052184 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 123.7" "Group enriched" "Detected in many" 4 "Distal enterocytes: 47.1;Endothelial cells: 65.2;Hepatic stellate cells: 146.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 90.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA013742 Enhanced NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA013742: AB_2668877" "unprognostic (4.39e-3)" "unprognostic (2.84e-1)" "unprognostic (1.33e-1)" "prognostic favorable (9.69e-4)" "unprognostic (8.53e-2)" "unprognostic (2.32e-3)" "prognostic favorable (9.24e-5)" "unprognostic (1.92e-1)" "unprognostic (1.29e-1)" "unprognostic (7.60e-2)" "unprognostic (2.04e-2)" "unprognostic (6.87e-2)" "unprognostic (5.63e-3)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.78e-1)" "unprognostic (1.45e-1)" "unprognostic (3.07e-2)" 30.4 42.5 1.6 16.8 1.6 0.0 18.1 1.3 2.7 30.9 9.1 24.7 10.2 46.3 6.1 18.8 28.3 18.8 26.4 1.5 1.6 52.8 2.4 123.7 9.2 2.0 1.6 5.2 20.8 28.7 15.8 23.4 2.2 36.5 18.0 0.0 20.8 84.7 2.1 13.5 29.3 33.5 1.9 24.2 23.6 1.3 2.3 8.4 89.3 3.4 9.6 21.3 20.3 1.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.5 4.3 0.5 0.0 0.1 0.1 0.0 90.6 0.9 0.0 11.2 0.1 0.0 0.1 0.1 0.1 0.0 5.8 0.0 2.4 0.0 0.0 3.4 0.2 0.0 0.2 0.0 1.5 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.6 6.0 0.0 0.0 0.0 0.0 8.7 0.0 0.1 0.0 4.6 1.5 0.0 3.7 0.1 0.0 22.1 0.0 4.5 0.1 0.4 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 1.6 1.3 2.7 1.5 1.6 2.0 1.6 2.2 1.9 2.3 1.7 19.8 0.0 2.5 0.0 2.1 5.1 9.1 0.5 8.6 0.0 0.8 3.9 4.6 1.5 1.6 3.7 0.0 1.5 0.0 47.1 0.0 2.8 1.0 0.9 0.2 65.2 1.2 0.0 8.1 3.3 4.0 8.7 18.8 1.6 1.3 0.1 146.7 0.6 0.2 0.0 1.7 4.1 0.0 2.2 0.4 0.8 0.3 0.7 0.0 2.8 0.0 0.0 0.0 0.0 0.1 14.0 15.8 0.0 0.0 1.5 3.2 2.1 0.8 0.0 0.0 0.4 1.1 0.4 0.2 2.0 1.7 0.8 1.1 0.1 0.6 2.2 SMAD4 "DPC4, MADH4" ENSG00000141646 "SMAD family member 4" Q13485 18 51028394-51085045 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019154 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" Centrosome "HPA019154: AB_1853480" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (4.83e-2)" "unprognostic (1.17e-2)" "unprognostic (4.05e-1)" "unprognostic (7.29e-3)" "unprognostic (9.00e-2)" "unprognostic (4.01e-2)" "unprognostic (2.51e-2)" "unprognostic (1.03e-3)" "unprognostic (4.40e-2)" "prognostic favorable (1.92e-5)" "unprognostic (2.62e-2)" "unprognostic (4.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" 16.4 11.8 9.0 10.9 10.3 10.6 17.2 21.7 10.5 18.5 11.2 14.9 11.9 20.6 9.8 15.7 16.3 12.8 14.1 11.7 10.0 16.1 19.1 13.1 12.7 9.0 8.2 24.0 21.4 19.9 11.3 18.9 9.4 21.8 14.3 18.3 14.0 18.0 24.9 14.6 12.1 18.9 8.0 13.9 15.2 14.2 11.9 17.7 21.4 24.9 14.5 13.5 13.1 13.8 16.4 22.5 59.4 16.6 23.9 36.6 31.4 27.7 32.2 39.4 49.6 13.0 3.8 25.9 7.8 25.6 19.6 24.9 33.6 13.2 40.7 19.3 14.8 20.6 20.5 15.9 23.7 34.8 13.1 16.6 21.9 19.1 27.8 37.0 28.7 14.0 21.9 25.8 23.5 9.0 18.8 10.0 31.2 9.1 14.3 23.3 30.6 26.9 18.2 7.4 34.4 20.3 27.0 5.0 18.8 24.8 13.3 19.4 20.0 34.5 13.3 8.8 19.7 30.6 28.6 26.2 21.2 12.8 22.6 0.3 0.6 0.6 1.0 0.4 1.1 0.7 1.0 0.8 1.2 0.9 1.2 1.5 1.0 1.0 0.4 1.0 1.4 0.5 9.0 10.3 21.7 10.5 11.7 10.0 9.0 8.2 9.4 8.0 11.9 13.8 32.5 22.4 29.1 55.2 21.0 25.6 20.9 15.1 18.8 17.1 27.3 20.4 38.8 24.3 19.3 22.0 20.9 20.7 24.0 22.7 11.7 16.9 10.6 30.4 36.6 26.2 39.6 12.4 37.0 12.5 20.6 30.3 28.5 35.2 4.5 132.4 28.5 44.1 15.1 15.2 39.0 32.1 16.2 28.5 20.9 16.2 33.2 21.1 28.4 49.6 16.9 20.4 17.5 41.2 72.5 20.1 21.0 30.5 24.8 36.3 26.7 22.6 22.4 20.0 26.3 32.2 34.2 17.2 18.8 20.9 27.3 12.6 20.1 22.1 24.5 29.7 SMOC2 SMAP2 ENSG00000112562 "SPARC related modular calcium binding 2" Q9H3U7 6 168441151-168673445 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 149.8;Leydig cells: 321.8;Peritubular cells: 769.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.1;EFO-21: 2.8;RPMI-8226: 11.3;RPTEC TERT1: 3.8;SuSa: 9.1" "Region enhanced" "Detected in many" "hippocampal formation: 25.7" "Region enhanced" "Detected in single" "spinal cord: 1.4" "Secreted to extracellular matrix" NA NA 120000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.23e-1)" "unprognostic (5.29e-2)" "unprognostic (3.70e-2)" "unprognostic (1.53e-2)" "unprognostic (2.43e-2)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (4.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.16e-6)" "unprognostic (3.50e-2)" "unprognostic (2.68e-1)" "unprognostic (6.35e-2)" "unprognostic (6.20e-3)" 67.8 14.0 10.6 13.0 12.7 0.0 61.0 10.8 16.2 82.1 42.3 44.1 21.4 164.0 147.2 53.1 119.6 100.8 57.2 10.6 11.3 13.0 4.0 14.7 14.7 11.8 11.8 124.1 25.2 12.2 4.5 18.8 11.9 31.0 24.9 2.8 17.1 54.6 42.1 28.9 27.8 76.5 10.2 4.4 144.7 44.2 12.2 10.9 43.5 54.8 11.1 68.7 21.8 10.0 2.4 0.0 8.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.4 1.0 0.0 0.0 0.0 0.0 11.3 3.8 0.0 1.7 0.3 0.0 0.3 0.1 9.1 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.6 12.7 10.8 16.2 10.6 11.3 11.8 11.8 11.9 10.2 12.2 10.0 8.1 0.0 1.7 0.7 0.0 11.1 8.0 0.0 1.2 7.1 12.5 12.1 7.7 0.0 1.8 11.0 0.0 2.5 0.0 3.6 0.0 0.0 2.6 40.3 42.3 11.0 19.7 0.0 0.5 0.0 1.7 149.8 1.1 58.4 0.0 17.2 3.3 0.0 1.2 0.0 9.7 4.5 0.0 0.0 3.9 17.2 321.8 2.9 3.6 6.5 0.0 0.4 0.0 2.0 0.1 0.1 0.4 769.2 0.1 6.7 2.0 0.0 2.2 0.8 46.0 14.7 63.3 3.9 5.1 0.8 2.7 2.6 1.7 17.3 47.4 1.1 SOS1 "GF1, GINGF, HGF" ENSG00000115904 "SOS Ras/Rac guanine nucleotide exchange factor 1" Q07889 2 38981549-39124345 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 226.6;Inhibitory neurons: 224.0;Microglial cells: 161.1;Oligodendrocyte precursor cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HMC-1: 134.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005396 Uncertain Approved Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB005396: AB_2270724" "unprognostic (6.68e-2)" "unprognostic (2.12e-2)" "unprognostic (1.01e-1)" "unprognostic (4.14e-3)" "unprognostic (4.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.74e-3)" "unprognostic (4.55e-2)" "unprognostic (1.10e-1)" "unprognostic (4.13e-2)" "unprognostic (1.24e-2)" "unprognostic (3.18e-2)" "unprognostic (1.38e-2)" "unprognostic (8.96e-3)" "unprognostic (7.61e-2)" "unprognostic (5.59e-2)" "unprognostic (1.33e-2)" 17.5 8.4 8.2 14.8 10.2 10.8 9.8 14.1 10.3 13.1 6.8 11.0 14.7 14.3 10.3 12.3 11.2 13.5 9.5 9.7 10.8 11.0 11.9 11.0 16.9 9.5 10.2 20.1 9.1 17.1 0.1 17.0 9.5 13.4 12.9 13.2 9.0 12.2 13.7 9.4 15.6 13.8 6.7 12.5 11.5 10.3 8.7 15.4 15.1 16.4 17.8 13.5 0.1 10.6 24.8 15.1 22.8 16.2 29.1 35.0 23.8 15.3 18.7 12.0 11.4 16.3 14.6 35.8 10.3 20.1 18.5 14.4 26.9 13.9 22.1 36.3 11.9 55.5 12.8 22.0 11.8 17.9 134.9 21.6 20.5 16.3 15.8 19.5 18.9 8.1 23.9 16.4 15.4 13.5 19.4 15.8 14.3 30.4 10.4 21.5 20.5 10.5 12.1 19.8 22.0 22.0 18.3 32.3 18.2 18.5 10.4 9.3 21.5 19.8 16.0 15.7 15.4 19.3 20.9 18.4 15.8 17.3 12.0 0.0 0.5 1.4 1.3 0.7 1.9 1.6 1.3 1.4 0.4 1.0 1.5 1.4 0.6 2.7 0.9 0.6 0.9 0.4 8.2 10.2 14.1 10.3 9.7 10.8 9.5 10.2 9.5 6.7 8.7 10.6 72.3 16.0 31.2 120.5 20.9 20.8 15.5 10.9 19.9 19.0 18.4 16.9 33.9 18.6 17.8 9.2 10.4 10.2 27.6 19.5 1.9 11.0 64.9 30.0 36.6 43.2 12.0 12.8 226.6 11.9 8.4 22.9 21.4 34.0 3.8 30.0 12.8 18.6 10.3 8.4 224.0 16.9 26.4 19.1 13.2 11.4 22.7 19.9 7.2 161.1 19.6 15.1 26.8 173.4 125.2 14.2 14.6 21.8 37.5 25.3 28.0 12.8 20.4 11.2 6.6 27.1 22.7 11.3 7.0 17.1 25.3 10.4 33.2 18.4 17.0 28.4 SP110 "IFI41, IFI75" ENSG00000135899 "SP110 nuclear body protein" Q9HB58 2 230165186-230225729 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 53.7" "Cell type enhanced" "Detected in many" "B-cells: 141.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 99.3" "Low region specificity" "Detected in all" HPA058554 Supported Nucleoplasm No No "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA058554: AB_2683754" "unprognostic (9.72e-2)" "unprognostic (1.15e-2)" "unprognostic (5.02e-2)" "unprognostic (8.33e-4)" "unprognostic (2.93e-1)" "unprognostic (1.80e-1)" "unprognostic (6.65e-2)" "unprognostic (9.44e-2)" "unprognostic (9.68e-2)" "unprognostic (1.46e-2)" "unprognostic (4.11e-3)" "unprognostic (2.55e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.38e-1)" "unprognostic (2.66e-2)" "unprognostic (2.99e-3)" "unprognostic (9.50e-3)" 14.0 7.3 8.4 38.5 10.3 29.8 11.8 9.4 10.8 11.6 11.5 12.6 11.9 10.5 7.9 9.2 9.6 18.0 8.1 8.1 10.3 11.9 14.8 21.0 53.7 15.3 10.9 16.5 7.9 9.7 5.3 17.5 11.6 9.6 14.0 2.0 17.0 7.6 5.7 7.8 17.6 13.4 12.1 49.8 12.9 3.1 10.9 35.7 7.4 8.4 50.1 18.9 9.3 12.3 8.3 4.4 2.7 4.7 14.2 23.6 8.3 14.8 30.8 70.3 99.3 0.2 12.7 34.5 13.8 15.8 67.0 5.1 9.0 23.0 25.7 30.5 6.0 14.9 6.2 8.9 14.5 22.1 17.1 32.7 11.8 20.8 27.4 13.2 25.3 23.6 5.3 12.1 20.6 4.9 33.0 43.5 8.6 4.2 5.1 20.1 25.4 12.8 56.2 11.1 0.5 5.7 5.7 12.7 32.7 0.9 9.6 18.5 18.8 12.9 7.9 3.2 7.5 12.9 4.6 16.2 14.4 20.6 10.7 92.2 49.7 124.4 55.2 85.8 47.8 142.8 53.5 50.5 44.1 135.8 54.1 58.7 268.6 56.9 143.4 84.4 70.7 48.5 8.4 10.3 9.4 10.8 8.1 10.3 15.3 10.9 11.6 12.1 10.9 12.3 77.8 44.8 23.8 17.3 141.7 9.9 5.2 25.7 16.5 0.4 21.6 19.3 3.7 7.2 19.6 11.0 0.0 3.8 84.0 17.0 13.7 19.9 5.2 17.2 21.3 28.6 6.7 9.7 1.1 28.5 12.7 22.8 9.2 20.1 38.0 21.2 26.4 6.2 26.9 0.0 2.1 11.4 73.2 47.4 25.8 4.2 11.8 62.3 19.6 42.2 56.7 9.7 59.8 19.6 18.2 26.0 11.6 10.1 35.7 3.5 10.7 14.4 21.0 4.9 6.6 8.6 16.2 4.8 2.3 9.8 10.1 4.7 68.8 23.5 6.1 3.0 SPINK1 "PCTT, PSTI, Spink3, TATI" ENSG00000164266 "Serine peptidase inhibitor Kazal type 1" P00995 5 147824572-147831671 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 36 "pancreas: 53063.4" "Group enriched" "Detected in many" 9 "Exocrine glandular cells: 50621.7;Pancreatic endocrine cells: 16750.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 513.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "CACO-2: 417.2;RT4: 1139.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026366, HPA027498" Enhanced "Secreted to digestive system" NA NA 8000000 "Cluster 25: Pancreas - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "CAB026366: , HPA027498: AB_10603115" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (9.96e-3)" "unprognostic (3.55e-1)" "unprognostic (6.12e-3)" "unprognostic (1.79e-4)" "unprognostic (8.34e-3)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "unprognostic (1.88e-1)" "unprognostic (3.82e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (5.44e-7)" "unprognostic (7.98e-2)" "unprognostic (2.07e-1)" "prognostic favorable (2.15e-5)" 8.8 1.5 0.1 36.4 0.1 6.8 4.1 0.3 1.2 3.1 0.3 428.2 394.4 5.5 0.8 2.9 1.3 111.9 12.0 0.2 0.2 142.5 491.8 2.7 2.7 0.1 0.1 25.6 53063.4 0.0 1.9 3.2 0.2 4.4 441.3 0.6 12.8 1.4 1.2 21.1 403.9 14.1 0.0 2.5 1475.2 0.9 0.3 0.4 1.0 0.0 0.3 995.6 10.8 0.6 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 417.2 0.3 0.1 6.8 0.0 0.8 0.9 2.2 0.0 0.0 3.9 0.0 0.0 0.0 107.0 0.3 0.0 3.9 0.0 2.1 0.0 3.0 5.8 0.0 0.0 0.0 0.3 0.0 0.3 0.8 1.3 2.1 138.9 0.8 0.8 0.0 2.5 0.0 1139.0 0.5 1.7 0.0 0.2 0.1 5.4 0.1 0.0 0.0 0.1 13.7 1.1 3.8 2.2 5.9 3.0 16.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 1.2 0.2 0.2 0.1 0.1 0.2 0.0 0.3 0.6 0.0 0.0 3.6 0.0 9.7 0.0 15.1 0.3 0.0 0.0 5.5 0.8 0.1 1451.2 11.1 377.0 0.0 0.0 0.0 280.8 86.1 1286.7 0.1 0.3 0.4 9.4 517.2 18.7 1.0 50621.7 0.1 1.9 1580.5 5.0 4.5 2.0 39.3 3385.8 0.1 0.0 0.2 2087.4 0.0 30.9 0.0 0.2 0.0 13.7 0.0 0.0 269.8 0.0 0.0 0.0 0.1 16750.7 563.8 0.0 1.3 173.5 1457.1 1.6 0.7 0.0 0.0 0.0 43.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 1365.3 649.1 SPINT2 "HAI-2, Kop" ENSG00000167642 "Serine peptidase inhibitor, Kunitz type 2" O43291 19 38244035-38292615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1371.3;Syncytiotrophoblasts: 1413.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 852.5;CAPAN-2: 1219.1;OE19: 1500.4;RPTEC TERT1: 896.7;SK-BR-3: 789.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011101, CAB018969" Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Intermediate filaments, Cytosol" "CAB018969: , HPA011101: AB_1079039" "unprognostic (5.13e-2)" "unprognostic (1.06e-3)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.03e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.04e-1)" "prognostic favorable (3.41e-4)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" 10.5 44.6 56.9 65.3 57.3 81.1 178.5 47.2 66.3 145.6 80.0 297.0 247.4 44.6 269.6 351.9 189.7 105.1 13.6 58.9 92.9 216.1 14.3 138.3 37.4 52.0 54.8 83.3 234.2 252.9 435.9 156.4 56.2 181.8 251.7 23.6 503.9 111.3 1.8 257.0 267.0 19.0 47.6 50.2 219.4 215.7 70.3 82.6 321.3 0.9 101.3 140.1 157.6 51.0 852.5 603.0 3.0 3.4 0.4 0.0 387.4 16.2 1.7 1.2 2.6 426.8 1219.1 6.7 65.8 4.6 1.2 274.6 42.7 587.0 1.4 7.9 51.7 159.4 15.3 0.9 0.9 1.5 0.8 0.1 662.5 0.7 278.6 71.5 2.0 144.2 4.0 0.4 1.0 652.8 25.6 2.8 60.4 1500.4 172.1 87.9 0.6 386.2 896.7 707.4 222.2 3.4 246.5 789.2 2.1 231.0 353.7 104.5 0.7 1.2 4.7 3.4 3.2 56.1 76.4 47.6 1.0 11.2 1.0 515.9 127.4 531.9 3.8 91.1 7.9 143.2 44.2 21.5 297.7 160.4 86.1 80.4 56.4 19.0 64.4 523.5 19.1 142.8 56.9 57.3 47.2 66.3 58.9 92.9 52.0 54.8 56.2 47.6 70.3 51.0 8.0 368.6 233.9 10.4 90.9 376.9 563.9 954.0 278.9 14.3 487.2 518.2 2.8 316.0 655.6 559.1 6.2 1371.3 79.5 1028.3 101.8 866.9 61.8 401.4 47.3 24.3 360.5 83.9 20.7 659.8 502.0 34.6 234.5 490.4 115.5 371.8 32.5 2.0 230.3 3.3 39.8 672.8 734.5 55.5 139.0 55.6 19.0 133.6 88.9 24.4 364.3 129.6 1.0 4.5 9.0 910.4 889.4 17.0 61.3 684.9 918.6 208.8 495.1 17.2 52.6 1.2 76.7 545.2 264.1 507.7 428.3 1413.2 42.6 3.4 582.2 989.6 STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228431 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 154.9;Late spermatids: 338.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: AB_2685847" "unprognostic (8.60e-2)" "unprognostic (1.68e-1)" "unprognostic (5.00e-2)" "prognostic favorable (3.69e-5)" "unprognostic (2.04e-2)" "prognostic favorable (1.96e-4)" "unprognostic (9.11e-3)" "unprognostic (3.19e-1)" "unprognostic (9.08e-2)" "unprognostic (1.26e-1)" "unprognostic (1.95e-3)" "unprognostic (7.70e-3)" "unprognostic (3.54e-2)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.12e-3)" 32.1 44.2 18.8 18.2 15.5 34.1 32.3 24.8 23.5 35.4 24.7 38.7 25.6 33.6 5.5 39.7 34.9 11.8 48.4 18.3 14.7 36.4 45.5 30.5 20.5 19.2 19.4 37.9 34.2 16.1 36.8 12.6 15.2 39.3 7.7 5.7 29.7 16.1 108.2 40.2 37.7 9.6 16.3 48.3 38.1 102.4 17.6 15.0 34.3 27.7 12.9 34.4 35.0 14.9 50.0 25.8 19.9 35.9 18.6 17.0 35.5 24.0 27.7 25.1 25.4 22.5 37.1 31.9 24.8 27.8 11.2 32.3 20.1 41.9 8.2 60.2 37.8 34.8 1.7 26.4 38.1 36.6 53.5 30.5 28.9 19.4 29.2 22.3 25.2 28.1 63.1 51.1 13.9 39.3 31.9 27.7 33.0 19.6 25.1 50.0 20.0 36.1 21.1 39.7 39.8 26.6 0.0 19.7 24.2 11.4 30.3 55.2 33.7 24.6 25.0 45.2 38.7 85.3 38.1 25.7 22.6 48.1 25.5 1.7 3.3 3.9 0.4 5.5 0.3 2.3 0.8 1.4 1.6 0.7 0.7 0.6 9.9 1.4 5.7 0.8 0.6 0.5 18.8 15.5 24.8 23.5 18.3 14.7 19.2 19.4 15.2 16.3 17.6 14.9 24.5 6.4 13.7 12.7 10.5 16.7 7.4 9.5 9.6 25.5 22.0 18.4 13.7 15.7 9.0 23.9 18.8 7.5 20.1 44.4 7.9 9.4 154.9 18.0 18.1 15.7 15.0 27.3 7.9 14.0 5.3 13.2 21.9 17.8 2.5 80.3 15.4 31.6 15.2 18.5 8.5 33.1 6.1 18.3 26.4 338.7 24.5 20.7 16.0 11.2 20.4 21.2 9.2 9.0 6.5 16.7 29.3 20.7 10.2 15.1 27.5 11.0 9.3 21.0 13.1 21.5 23.7 85.5 20.1 14.6 15.5 8.8 16.6 45.2 35.4 12.6 TJP2 "DFNA51, X104, ZO-2, ZO2" ENSG00000119139 "Tight junction protein 2" Q9UDY2 9 69121264-69274615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 212.4;Rod photoreceptor cells: 267.6;Urothelial cells: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 237.5" "Low region specificity" "Detected in all" "HPA001813, CAB009228, HPA070714" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 580000 "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB009228: AB_2203583, HPA001813: AB_1080764, HPA070714: AB_2732161" "unprognostic (1.30e-1)" "unprognostic (7.69e-2)" "unprognostic (1.23e-3)" "unprognostic (7.68e-2)" "unprognostic (2.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.82e-2)" "unprognostic (3.30e-2)" "unprognostic (2.93e-3)" "unprognostic (3.60e-1)" "prognostic favorable (1.78e-14)" "unprognostic (3.29e-2)" "unprognostic (6.42e-2)" "unprognostic (8.15e-3)" "unprognostic (5.85e-2)" 44.4 14.9 35.1 11.6 45.3 12.0 30.2 44.5 42.6 16.9 25.7 39.0 54.4 19.8 13.1 45.8 23.8 24.4 35.8 38.0 45.4 44.7 64.8 47.6 9.7 52.6 39.9 37.0 21.9 57.9 5.3 18.4 52.6 24.8 35.1 122.0 37.1 21.9 14.1 35.0 49.6 16.1 55.0 5.7 58.3 32.1 39.9 32.5 44.9 15.1 23.1 55.3 22.3 66.3 237.5 6.4 24.4 25.8 92.9 90.3 108.5 37.3 26.7 54.9 29.0 31.8 106.6 33.0 37.0 20.3 31.4 158.3 33.2 79.3 75.9 115.3 20.7 34.5 22.5 165.2 28.9 13.8 59.1 71.3 65.2 43.1 32.4 19.6 143.6 9.9 19.7 24.7 34.3 36.0 5.5 2.3 49.5 194.5 50.0 23.1 26.9 2.9 192.0 194.2 8.3 14.9 13.3 111.2 3.4 55.7 37.0 7.9 196.3 44.3 48.3 32.4 38.6 23.0 5.2 0.9 48.0 19.6 16.1 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.8 0.1 35.1 45.3 44.5 42.6 38.0 45.4 52.6 39.9 52.6 55.0 39.9 66.3 2.9 44.8 22.8 76.4 2.3 65.1 79.1 26.3 4.6 212.4 4.6 1.3 38.5 40.0 33.1 3.7 35.5 27.9 2.7 74.4 0.0 32.5 3.5 7.1 1.7 36.4 11.5 10.5 10.1 24.3 25.6 15.5 64.2 9.9 5.7 0.2 27.5 104.9 5.6 18.5 13.4 45.0 36.7 14.6 28.9 6.7 29.2 8.2 28.4 22.5 9.0 111.1 1.0 21.6 82.5 44.2 65.8 13.9 5.2 115.4 73.4 1.9 51.3 267.6 0.0 4.9 13.1 19.6 18.0 40.6 64.1 43.2 3.2 0.2 50.3 244.5 UTP4 "CIRH1A, CIRHIN, FLJ14728, KIAA1988, NAIC, TEX292" ENSG00000141076 "UTP4 small subunit processome component" Q969X6 16 69131291-69231130 "Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 100.0;Spermatogonia: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 398.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041139, HPA043542" Approved Supported "Nucleoli fibrillar center" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli fibrillar center" "HPA041139: AB_10961278, HPA043542: AB_2678542" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (1.48e-1)" "unprognostic (1.89e-2)" "unprognostic (6.16e-3)" "prognostic unfavorable (9.05e-5)" "prognostic unfavorable (8.18e-7)" "unprognostic (1.31e-1)" "unprognostic (4.76e-2)" "prognostic favorable (2.88e-5)" "unprognostic (2.12e-2)" "unprognostic (4.45e-2)" "unprognostic (2.32e-3)" "unprognostic (9.57e-3)" "unprognostic (2.12e-1)" "unprognostic (1.33e-1)" "unprognostic (3.20e-2)" 25.4 17.4 7.7 17.5 8.6 27.1 21.0 7.3 10.1 16.3 7.3 21.1 10.8 20.6 9.9 23.0 19.5 12.7 19.2 10.3 7.5 31.7 19.1 16.3 19.1 6.1 6.9 18.3 24.1 16.6 14.2 15.5 6.6 16.1 17.6 11.4 15.7 14.4 61.7 20.2 13.9 22.7 5.9 14.0 19.1 31.4 8.0 17.6 23.2 26.3 23.3 28.8 16.8 7.3 79.6 95.6 56.9 79.8 48.5 42.9 94.5 83.7 57.2 152.1 112.8 188.1 68.8 166.4 68.0 57.7 63.1 106.0 130.8 102.7 167.4 33.2 74.6 82.2 58.6 99.7 58.6 96.5 52.7 41.0 55.2 143.0 129.5 40.7 68.6 88.8 169.4 22.9 90.0 96.2 105.4 50.5 139.1 80.3 66.7 174.3 85.3 163.4 63.6 77.7 96.4 67.1 178.3 45.3 48.3 63.3 80.2 53.4 48.2 83.3 83.6 73.4 119.2 59.5 116.1 398.1 56.5 76.5 87.4 4.5 18.6 3.5 26.7 26.1 38.5 30.6 30.0 26.9 25.6 20.1 34.7 31.6 1.7 35.0 19.4 21.6 31.5 30.2 7.7 8.6 7.3 10.1 10.3 7.5 6.1 6.9 6.6 5.9 8.0 7.3 12.1 6.4 11.4 0.0 14.6 0.0 30.0 0.0 28.5 5.7 12.4 11.6 0.0 5.7 9.9 5.5 8.4 18.9 7.4 1.7 9.8 27.4 17.9 7.0 13.2 12.1 0.0 12.4 0.0 25.4 22.1 14.8 10.2 9.0 2.5 12.0 9.3 7.9 16.7 6.7 0.0 6.4 0.0 8.9 0.0 7.6 15.8 9.8 0.0 0.0 8.2 7.6 11.3 0.0 0.0 24.4 5.4 14.7 13.4 26.7 4.5 100.0 5.8 5.7 6.6 26.7 12.8 30.1 49.5 25.1 0.0 12.9 11.0 16.5 10.0 22.6 WDR72 FLJ38736 ENSG00000166415 "WD repeat domain 72" Q3MJ13 15 53513741-53762878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 105.7;liver: 33.1;thyroid gland: 57.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 12.8;Collecting duct cells: 22.0;Glandular and luminal cells: 13.2;Hepatocytes: 44.3;Proximal tubular cells: 93.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 9.9;OE19: 18.3;RPMI-8226: 17.5;RPTEC TERT1: 10.1;SuSa: 15.2;U-266/70: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048212, HPA057410, HPA059819" Uncertain Approved Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA048212: AB_2680315, HPA057410: AB_2683430, HPA059819: AB_2684133" "unprognostic (6.39e-4)" "unprognostic (1.41e-1)" "unprognostic (3.19e-2)" "unprognostic (1.79e-2)" "unprognostic (2.63e-2)" "unprognostic (3.37e-2)" "unprognostic (5.54e-2)" "unprognostic (2.20e-1)" "unprognostic (1.13e-1)" "unprognostic (1.26e-1)" "unprognostic (2.78e-2)" "unprognostic (1.09e-2)" "prognostic favorable (3.33e-16)" "unprognostic (2.83e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (7.67e-2)" 0.1 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.1 7.2 0.0 0.6 2.6 1.4 0.5 0.4 2.6 3.9 0.1 0.0 0.1 105.7 33.1 0.8 0.1 0.1 0.4 0.2 3.5 1.8 0.3 0.1 0.1 0.1 0.8 0.7 18.4 0.6 0.0 2.0 0.9 0.0 0.0 0.1 1.1 0.5 0.1 0.0 57.9 0.0 0.0 1.7 0.0 0.3 0.0 9.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 3.2 0.1 6.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.9 18.3 0.1 0.0 0.1 17.5 10.1 3.5 1.9 0.0 0.0 0.1 0.0 15.2 2.4 0.0 0.1 0.3 0.5 0.0 0.1 7.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.1 0.3 0.1 6.4 3.6 0.0 0.5 0.1 1.1 0.0 0.6 0.5 0.0 0.1 0.6 12.8 0.0 22.0 0.0 0.6 0.0 0.2 9.8 3.2 1.2 4.9 1.0 0.1 0.0 0.0 0.4 0.5 2.1 0.2 0.0 13.2 0.0 0.0 0.0 44.3 0.1 3.3 0.5 0.0 0.0 0.6 0.0 0.3 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 93.2 0.1 0.1 0.0 0.0 0.1 1.0 1.6 0.9 0.4 0.1 0.7 0.0 0.3 6.4 WNT10A ENSG00000135925 "Wnt family member 10A" Q9GZT5 2 218880852-218899581 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant, Ectodermal dysplasia, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 7.0;skin 1: 8.9" "Cell type enhanced" "Detected in many" "B-cells: 12.2;Basal keratinocytes: 17.1;Basal respiratory cells: 15.5;Basal squamous epithelial cells: 30.1;Bipolar cells: 16.2;dendritic cells: 16.4;Plasma cells: 30.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.9" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 6.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 6.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 50.8;HaCaT: 140.1;HDLM-2: 58.7;RPTEC TERT1: 29.2;U-266/70: 69.0" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Region enhanced" "Detected in single" "basal ganglia: 2.1" HPA013898 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "HPA013898: AB_1858847" "unprognostic (2.99e-4)" "unprognostic (4.31e-2)" "unprognostic (8.55e-2)" "unprognostic (1.17e-3)" "unprognostic (2.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.62e-1)" "unprognostic (2.56e-2)" "unprognostic (1.04e-1)" "unprognostic (6.34e-2)" "unprognostic (2.23e-3)" "unprognostic (9.52e-2)" "unprognostic (6.64e-9)" "unprognostic (1.22e-1)" "unprognostic (1.72e-1)" "unprognostic (4.89e-3)" "unprognostic (1.82e-1)" 0.7 0.2 0.7 1.0 1.6 0.5 0.5 0.2 1.3 1.5 0.2 1.6 3.7 0.0 0.4 7.0 1.2 0.3 0.1 1.2 0.5 2.4 0.2 0.7 2.5 0.4 0.6 0.2 0.1 0.0 4.3 3.4 0.5 1.7 1.0 1.4 2.5 1.0 0.0 8.9 2.1 0.0 0.3 2.0 2.5 0.4 0.7 1.1 0.2 0.0 1.9 2.7 2.9 0.7 15.8 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 50.8 2.8 10.4 0.0 3.8 140.1 0.0 0.1 0.0 58.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 10.5 29.2 0.4 0.0 0.4 0.3 0.0 0.1 0.8 0.0 0.2 0.0 0.0 0.9 0.0 0.0 69.0 1.1 1.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.7 0.2 0.0 0.0 0.0 0.0 6.2 1.0 0.0 0.7 1.6 0.2 1.3 1.2 0.5 0.4 0.6 0.5 0.3 0.7 0.7 0.2 0.0 0.0 0.3 12.2 17.1 8.2 15.5 30.1 16.2 0.5 1.3 1.4 0.0 1.1 9.2 2.1 1.2 16.4 0.0 0.0 0.3 1.2 0.3 0.1 0.2 0.0 0.4 1.3 0.0 0.4 1.9 0.5 0.2 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.0 2.0 0.0 1.3 0.1 0.6 1.0 7.2 0.0 0.0 0.5 0.0 0.5 0.1 0.1 0.0 0.0 30.4 2.5 0.0 0.3 0.6 1.5 0.0 0.1 0.8 0.9 0.6 5.2 4.7 0.1 9.8 0.0 0.2 3.2 WNT10B "SHFM6, WNT-12" ENSG00000169884 "Wnt family member 10B" O00744 12 48965340-48971735 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.3;Extravillous trophoblasts: 21.7;Fibroblasts: 4.8;Inhibitory neurons: 4.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 7.3;T-47d: 8.2;U-266/84: 7.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA055048, HPA062539" Enhanced Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA055048: AB_2682683, HPA062539: AB_2684793" "unprognostic (1.13e-1)" "unprognostic (2.14e-2)" "unprognostic (5.73e-4)" "unprognostic (2.27e-2)" "unprognostic (3.09e-2)" "unprognostic (3.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.14e-1)" "unprognostic (4.99e-3)" "unprognostic (3.05e-2)" "unprognostic (5.39e-6)" "unprognostic (4.29e-2)" "unprognostic (3.74e-2)" "unprognostic (4.50e-1)" "unprognostic (1.25e-1)" 1.5 0.2 13.1 1.5 14.9 1.2 0.6 4.2 17.9 0.8 3.2 1.4 1.4 0.3 1.5 1.4 1.0 0.5 1.5 15.3 7.3 0.4 0.4 1.1 1.7 8.6 7.6 0.2 0.3 0.1 2.4 0.3 8.2 0.8 0.7 0.1 0.9 0.6 0.7 3.4 4.3 0.1 5.1 4.1 1.1 3.3 10.4 1.9 1.0 0.4 1.5 1.3 1.0 9.8 1.9 1.2 0.0 1.7 0.0 0.0 4.6 1.3 2.4 0.5 0.1 3.6 4.0 0.0 0.3 0.2 1.5 2.2 4.8 0.3 0.2 1.1 6.3 2.1 1.7 0.1 0.0 0.7 2.9 0.0 0.4 0.1 2.1 4.1 0.0 1.5 7.3 0.3 0.7 2.4 0.1 2.5 0.0 1.3 2.5 0.0 0.6 2.2 0.0 0.4 0.1 0.0 0.3 0.1 0.6 2.2 8.2 2.7 0.0 2.5 4.9 0.4 0.6 2.6 7.8 0.0 1.0 5.4 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 13.1 14.9 4.2 17.9 15.3 7.3 8.6 7.6 8.2 5.1 10.4 9.8 0.2 0.0 0.0 0.7 0.2 0.4 0.0 0.0 1.8 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.8 0.2 0.1 0.0 0.0 0.0 7.3 0.0 21.7 4.8 0.0 0.1 0.0 0.0 0.7 0.0 0.3 0.0 4.7 0.2 0.0 0.0 1.2 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.7 3.0 0.9 1.3 1.4 1.6 0.0 0.0 0.1 WNT2B "WNT13, XWNT2" ENSG00000134245 "Wnt family member 2B" Q93097 1 112466541-112530165 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leydig cells: 80.2;Peritubular cells: 197.5" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.4;HSkMC: 8.0;SuSa: 3.4;TIME: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047274, HPA066368" Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA047274: AB_2732539, HPA066368: AB_2685664" "unprognostic (2.08e-3)" "unprognostic (2.06e-3)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (1.77e-1)" "unprognostic (1.49e-1)" "unprognostic (9.42e-2)" "unprognostic (4.90e-3)" "unprognostic (1.15e-1)" "unprognostic (2.37e-1)" "unprognostic (5.94e-2)" "unprognostic (1.13e-1)" "unprognostic (5.65e-4)" "unprognostic (5.41e-2)" "unprognostic (7.64e-2)" "unprognostic (4.80e-2)" "unprognostic (2.49e-2)" 4.5 1.9 2.0 1.5 4.9 0.1 2.8 2.1 2.8 8.2 2.0 5.6 3.0 4.9 2.8 5.8 4.7 2.8 4.3 1.9 1.7 2.4 1.0 6.3 0.8 1.8 1.7 10.9 1.8 0.6 2.3 4.8 1.9 6.1 5.3 5.5 2.2 13.9 1.6 11.1 5.2 2.2 1.4 1.7 3.8 3.8 1.8 0.2 1.9 0.8 0.7 5.6 9.1 2.3 0.4 0.3 2.2 0.5 2.2 4.4 0.4 1.0 1.0 0.2 0.4 0.2 0.5 1.1 0.2 1.1 0.2 1.4 0.7 0.3 0.2 0.0 0.4 0.1 0.8 0.3 1.8 0.2 0.5 8.0 0.8 0.4 0.1 1.3 1.2 0.3 0.1 0.2 0.2 0.3 0.1 0.1 0.3 0.0 0.3 0.1 0.3 0.0 1.5 0.3 0.3 0.3 0.7 0.1 0.7 3.4 0.0 0.2 3.5 0.3 1.4 0.8 0.3 0.1 0.1 0.0 0.9 0.1 0.9 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 2.0 4.9 2.1 2.8 1.9 1.7 1.8 1.7 1.9 1.4 1.8 2.3 7.6 12.8 3.3 2.0 2.0 10.1 1.8 6.1 5.2 14.1 2.1 0.9 6.5 1.5 3.9 1.8 27.1 2.1 2.4 3.5 0.0 0.8 5.6 2.6 3.6 10.2 8.4 2.1 5.5 1.4 0.8 17.7 1.1 6.8 2.5 2.8 6.1 0.2 1.1 5.0 6.2 2.2 4.1 2.1 8.2 3.4 80.2 4.0 3.6 30.9 2.2 9.8 0.0 11.6 7.1 2.0 4.8 197.5 2.5 4.4 2.9 0.9 4.6 27.6 0.0 9.7 2.7 5.9 5.5 26.4 13.9 1.9 1.9 2.0 1.5 2.6