Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCB6 "EST45597, MTABC3, umat" ENSG00000115657 "ATP binding cassette subfamily B member 6 (Langereis blood group)" Q9NP58 2 219209772-219218994 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Dyskeratosis congenita, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 14.7;Excitatory neurons: 12.9;Gastric mucus-secreting cells: 5.1;Inhibitory neurons: 10.9;Oligodendrocyte precursor cells: 13.6;Oligodendrocytes: 5.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 65.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046723, HPA058011" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Plasma membrane, Mitochondria, Cytosol" "HPA046723: AB_10960288, HPA058011: AB_2683578" "unprognostic (8.04e-2)" "unprognostic (3.22e-2)" "unprognostic (4.53e-3)" "unprognostic (3.19e-2)" "unprognostic (2.55e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (9.45e-7)" "unprognostic (2.26e-1)" "unprognostic (3.62e-2)" "unprognostic (1.53e-1)" "unprognostic (1.18e-4)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.51e-1)" "unprognostic (9.55e-2)" "unprognostic (7.75e-2)" "unprognostic (2.30e-1)" 10.2 8.7 4.3 3.4 3.9 10.4 7.6 3.2 4.6 7.7 4.4 6.5 6.9 8.4 8.2 11.4 9.6 7.1 8.5 4.0 5.1 5.2 15.9 5.9 1.9 4.4 4.2 12.9 5.7 4.8 6.0 3.1 6.2 8.0 3.3 3.0 6.2 8.6 30.4 6.8 6.3 7.9 4.1 3.9 7.9 18.0 5.7 2.6 10.7 9.8 2.9 14.9 7.9 5.0 0.3 22.9 4.7 28.8 30.8 11.1 27.6 8.5 7.9 9.2 9.2 35.5 5.0 0.3 42.8 8.6 5.0 49.1 0.6 3.6 3.0 15.0 4.7 36.3 24.9 65.8 37.0 0.0 12.0 16.3 4.2 6.2 0.1 13.9 16.3 4.8 31.4 4.4 6.3 12.0 2.3 0.1 7.2 53.6 9.2 12.3 14.3 1.6 5.1 0.4 16.6 17.8 17.6 41.4 18.7 17.4 12.4 0.8 7.5 12.5 0.5 16.9 10.3 11.2 9.6 0.1 14.0 0.4 17.0 0.7 0.4 0.0 0.7 0.4 0.2 1.0 0.5 0.2 0.3 0.8 1.2 0.8 0.0 0.4 0.3 2.3 0.5 1.0 4.3 3.9 3.2 4.6 4.0 5.1 4.4 4.2 6.2 4.1 5.7 5.0 0.2 0.0 0.0 14.7 0.3 0.3 0.0 0.5 1.2 1.0 0.2 0.0 0.2 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.0 0.8 1.2 0.3 0.6 0.4 0.0 1.3 12.9 0.0 0.1 0.7 5.1 0.2 0.0 0.5 0.0 0.4 0.1 0.0 10.9 0.3 0.0 0.3 0.4 1.0 0.3 0.3 0.0 3.7 0.0 0.3 0.0 13.6 5.6 0.3 0.0 0.4 0.5 0.0 0.5 0.2 2.2 0.8 0.0 0.4 0.3 1.0 0.3 2.8 0.3 0.3 0.1 0.4 0.2 0.1 ABCB7 "ABC7, ASAT, Atm1p, EST140535" ENSG00000131269 "ATP binding cassette subfamily B member 7" O75027 X 75051048-75156732 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034982 Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA034982: AB_10601010" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (1.49e-2)" "unprognostic (1.83e-3)" "unprognostic (4.44e-3)" "unprognostic (1.33e-2)" "unprognostic (6.31e-2)" "unprognostic (4.39e-2)" "unprognostic (1.47e-1)" "unprognostic (2.17e-1)" "unprognostic (4.14e-2)" "unprognostic (2.55e-2)" "prognostic favorable (5.31e-6)" "unprognostic (1.95e-1)" "unprognostic (1.27e-1)" "unprognostic (1.45e-1)" "unprognostic (1.08e-1)" 12.6 13.5 5.0 7.7 5.9 11.1 11.8 8.2 7.6 11.4 9.8 13.8 16.0 10.9 5.0 11.6 11.2 7.4 22.0 5.5 6.1 10.1 14.8 9.8 12.0 6.4 6.0 12.3 9.6 11.0 8.6 7.5 6.2 8.5 9.6 9.8 10.0 6.9 31.4 12.9 11.8 8.8 6.1 10.9 12.3 4.1 5.4 14.0 9.5 22.2 11.1 10.5 10.9 6.8 17.0 16.2 12.2 20.9 14.1 25.5 7.0 8.9 14.6 12.3 22.4 18.5 24.5 25.8 22.8 9.2 21.2 18.8 25.6 18.5 12.0 26.0 33.2 16.8 29.2 17.3 8.2 24.7 13.7 15.9 16.3 12.8 16.7 21.3 23.1 26.2 18.9 31.1 9.8 10.5 24.4 26.1 26.8 26.3 30.5 21.4 26.9 30.5 12.7 13.2 17.7 14.1 27.4 23.5 17.8 20.0 10.2 22.9 10.3 11.3 22.9 23.2 12.4 10.1 27.5 21.2 10.1 35.8 9.4 9.6 26.9 10.0 15.7 25.6 16.6 24.7 16.7 16.7 29.0 28.2 28.7 21.1 2.4 17.5 20.4 18.2 27.2 19.2 5.0 5.9 8.2 7.6 5.5 6.1 6.4 6.0 6.2 6.1 5.4 6.8 12.0 9.6 10.4 48.0 26.6 15.8 14.5 16.0 19.9 10.9 10.9 9.9 46.8 14.3 14.2 11.0 6.2 23.0 19.0 8.2 11.7 17.5 0.4 8.4 12.8 11.9 13.8 26.9 37.9 13.5 11.6 13.9 9.7 10.1 22.2 20.6 9.3 11.8 20.1 25.2 39.0 10.5 8.2 26.1 16.7 0.8 14.6 19.2 10.6 45.0 22.9 12.4 6.2 43.7 46.6 11.6 7.9 13.2 14.3 10.6 15.9 19.9 10.7 7.9 32.9 19.6 13.8 5.5 10.9 16.1 16.1 22.3 14.5 19.2 17.9 11.9 ABCG5 STSL ENSG00000138075 "ATP binding cassette subfamily G member 5" Q9H222 2 43812472-43838865 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 69 "intestine: 47.8;liver: 62.0" "Group enriched" "Detected in some" 6 "Hepatocytes: 60.3;Paneth cells: 23.9;Proximal enterocytes: 30.9" "Cancer enriched" "Detected in some" 23 "liver cancer: 11.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 54 "Hep G2: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.71e-1)" "unprognostic (5.47e-2)" "unprognostic (4.01e-1)" "unprognostic (6.92e-2)" "unprognostic (2.24e-1)" "unprognostic (9.97e-2)" "prognostic favorable (2.60e-5)" "unprognostic (4.59e-2)" "unprognostic (3.10e-1)" "unprognostic (1.38e-3)" "unprognostic (3.07e-4)" "unprognostic (1.86e-1)" "unprognostic (3.07e-1)" "unprognostic (5.52e-3)" "unprognostic (8.29e-2)" "unprognostic (5.31e-2)" "unprognostic (3.08e-2)" 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 47.8 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.2 0.0 62.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.6 5.7 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.0 0.1 0.6 0.1 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.7 60.3 0.0 0.0 3.2 2.5 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 1.8 0.0 23.9 0.0 0.0 0.0 30.9 0.0 0.0 0.7 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.7 0.0 ABCG8 GBD4 ENSG00000143921 "ATP binding cassette subfamily G member 8" Q9H221 2 43831942-43882988 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "intestine: 31.5;liver: 63.4" "Group enriched" "Detected in some" 4 "Hepatocytes: 32.0;Proximal enterocytes: 13.8" "Cancer enriched" "Detected in some" 30 "liver cancer: 21.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 44 "Hep G2: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA019556 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA019556: AB_1844444" "unprognostic (1.99e-1)" "unprognostic (4.49e-1)" "unprognostic (3.22e-1)" "unprognostic (1.37e-1)" "unprognostic (3.09e-2)" "unprognostic (2.43e-1)" "unprognostic (1.99e-3)" "unprognostic (1.27e-1)" "unprognostic (6.28e-1)" "unprognostic (6.14e-3)" "unprognostic (4.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.68e-1)" "unprognostic (7.86e-3)" "unprognostic (5.03e-1)" "unprognostic (1.50e-1)" 0.1 0.0 0.4 0.1 0.3 0.1 0.0 0.2 1.1 0.0 0.0 0.2 29.8 0.1 0.0 0.0 0.2 0.9 0.0 0.2 0.4 0.3 63.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 31.5 0.0 0.0 0.1 0.3 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.1 0.2 0.4 0.3 0.1 0.4 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.8 0.6 1.8 0.0 0.0 0.1 0.0 1.9 0.1 0.0 0.2 0.7 0.6 0.0 2.7 3.6 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.4 32.0 0.0 0.0 2.8 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 5.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.2 0.0 ACTN1 ENSG00000072110 "Actinin alpha 1" P12814 14 68874128-68979440 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 524.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 364.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004303, HPA006035" Approved Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 210000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB004303: AB_626633, HPA006035: AB_1078095" "unprognostic (4.40e-2)" "unprognostic (1.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (6.19e-3)" "prognostic unfavorable (7.63e-5)" "unprognostic (3.62e-1)" "unprognostic (3.23e-2)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.08e-10)" "unprognostic (2.87e-2)" "unprognostic (2.00e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (8.00e-4)" 117.4 40.7 27.3 149.5 55.8 149.3 103.5 0.1 32.0 118.4 20.1 449.8 49.8 313.1 60.3 154.4 152.1 143.9 121.4 29.7 14.7 46.7 61.8 100.0 47.5 24.5 11.0 61.8 46.8 9.1 27.3 96.1 7.3 174.3 109.0 28.2 116.4 295.1 21.7 59.3 106.9 524.5 4.2 55.9 171.7 21.2 32.9 32.6 35.0 13.3 50.7 305.9 83.3 28.8 871.9 262.3 158.6 121.4 275.2 180.5 592.4 749.3 712.0 770.0 571.1 211.8 196.6 0.7 256.5 744.7 310.4 370.9 126.8 790.3 965.2 4.6 38.5 118.2 133.5 179.0 494.0 85.4 14.3 231.7 152.1 479.8 540.3 551.6 428.6 48.2 56.9 1.4 612.0 246.9 10.1 181.1 124.7 217.9 198.1 59.3 294.1 32.6 292.0 225.6 57.0 68.7 649.9 96.8 177.1 474.8 146.0 170.9 546.0 1085.2 432.8 126.9 662.5 113.8 47.8 3.9 314.4 115.7 584.4 64.6 67.5 137.1 5.7 28.8 7.1 0.1 22.7 12.4 45.5 0.2 103.9 92.2 364.2 4.5 8.9 2.0 9.6 89.2 27.3 55.8 0.1 32.0 29.7 14.7 24.5 11.0 7.3 4.2 32.9 28.8 44.7 38.5 25.1 19.6 4.0 119.3 154.9 137.4 82.0 74.7 88.6 157.6 60.3 51.5 36.0 42.3 246.0 155.3 3.0 17.2 3.9 186.8 34.0 65.8 112.8 135.5 38.5 21.9 102.7 144.9 351.8 88.9 34.1 90.2 7.6 15.9 129.5 96.6 79.5 18.5 29.7 57.3 59.0 100.9 82.1 10.7 35.8 96.4 30.2 34.7 105.1 6.0 4.1 9.0 4.3 203.7 28.0 245.6 0.6 132.6 2.4 15.3 47.8 80.8 177.5 30.0 270.6 19.4 18.4 51.8 59.8 66.9 22.7 20.9 47.0 67.1 ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 63.8" "Cell type enhanced" "Detected in many" "Astrocytes: 16.0;Early spermatids: 19.3;Excitatory neurons: 12.4;Inhibitory neurons: 12.4;Late spermatids: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042014, HPA042844, HPA052077" Approved Approved Vesicles "Secreted to blood" NA NA 1300000000 120000000 "Cluster 34: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA042014: AB_2677798, HPA042844: AB_2678200, HPA052077: " "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (8.75e-4)" "unprognostic (1.49e-2)" "unprognostic (1.83e-1)" "unprognostic (3.02e-1)" "unprognostic (4.76e-2)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-1)" "unprognostic (4.52e-5)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.78e-2)" "unprognostic (3.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.30e-3)" 2.5 2.8 6.9 0.5 7.3 0.6 2.8 7.6 10.0 5.0 5.3 4.3 3.2 4.2 2.9 2.4 5.7 1.2 6.0 7.1 6.2 9.6 63.8 2.8 0.9 7.0 6.7 6.7 6.2 1.5 12.5 0.8 7.1 6.4 0.9 1.1 2.5 1.4 4.3 2.6 4.4 0.6 6.3 2.6 9.8 13.5 7.2 0.8 6.1 1.4 0.5 4.4 3.1 7.1 0.0 0.8 1.9 2.6 1.5 1.3 0.8 0.7 0.5 0.2 0.3 0.3 2.1 0.2 0.9 0.4 0.6 0.3 0.1 0.4 0.1 1.2 1.7 0.2 0.9 0.4 1.1 0.0 0.7 3.6 0.9 0.2 0.7 1.2 0.1 1.3 0.0 0.8 0.3 3.3 0.0 0.9 2.0 1.1 1.1 0.2 0.2 0.9 0.8 0.8 1.3 4.0 1.4 0.6 1.2 3.9 3.7 0.4 0.5 1.5 0.8 0.9 0.0 1.7 0.3 0.3 1.1 0.2 1.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 7.3 7.6 10.0 7.1 6.2 7.0 6.7 7.1 6.3 7.2 7.1 0.9 0.0 2.0 16.0 1.2 0.3 0.3 0.9 0.0 1.7 1.4 1.9 4.2 4.3 2.4 0.0 0.0 0.2 0.2 1.0 1.9 0.6 19.3 3.6 1.6 0.9 1.2 0.0 12.4 0.4 0.3 1.5 4.6 3.3 0.0 3.0 5.0 1.6 0.2 3.3 12.4 1.3 0.0 0.6 0.0 13.6 0.9 0.3 0.0 7.5 0.0 1.7 0.0 2.0 5.5 0.3 3.0 1.5 0.4 0.4 1.5 0.9 0.7 1.8 0.0 0.4 0.7 6.0 3.9 0.3 0.4 0.1 0.5 1.7 0.9 0.3 AK1 ENSG00000106992 "Adenylate kinase 1" P00568 9 127866486-127877675 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1346.2;tongue: 783.3" "Cell type enhanced" "Detected in all" "Early spermatids: 281.3;Late spermatids: 1031.8;Muller glia cells: 287.6;Peritubular cells: 386.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 163.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006456, CAB009893" Enhanced Supported Cytosol NA NA 24000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "CAB009893: AB_2225151, HPA006456: AB_1078116" "unprognostic (6.07e-3)" "unprognostic (1.44e-2)" "unprognostic (2.36e-2)" "unprognostic (1.03e-1)" "unprognostic (3.44e-1)" "unprognostic (3.09e-1)" "unprognostic (1.52e-2)" "unprognostic (3.12e-2)" "unprognostic (2.19e-1)" "unprognostic (5.74e-2)" "unprognostic (6.65e-3)" "unprognostic (2.07e-1)" "unprognostic (1.81e-2)" "prognostic favorable (7.31e-4)" "unprognostic (2.62e-1)" "unprognostic (8.40e-3)" "unprognostic (6.99e-3)" 28.5 34.5 81.3 11.5 79.2 28.4 17.0 87.9 95.1 37.5 145.8 33.8 17.9 14.3 28.5 32.0 342.2 22.5 270.0 79.5 88.5 31.4 26.5 74.6 5.0 97.4 99.8 45.0 14.9 47.0 33.8 7.6 99.0 17.1 39.5 29.0 33.1 35.9 1346.2 14.2 12.1 21.9 105.0 20.8 23.9 63.1 89.4 3.9 34.8 783.3 12.6 19.7 19.4 97.2 56.7 23.6 30.1 40.4 71.2 142.9 27.4 38.3 38.2 66.7 40.4 18.0 34.9 1.5 40.8 79.4 44.1 79.2 0.3 43.1 26.6 9.0 26.1 8.3 65.2 31.6 40.1 0.0 1.0 110.9 81.8 49.9 35.5 36.8 90.3 0.8 33.7 2.3 76.7 53.5 0.1 1.1 10.6 139.7 74.2 1.3 30.0 12.6 44.8 4.1 48.3 30.4 101.0 57.4 29.8 15.3 45.8 33.3 75.9 45.9 18.8 163.8 37.3 3.5 0.6 0.2 57.7 0.3 32.4 0.2 0.0 0.1 0.3 0.0 0.2 0.0 0.1 0.2 0.0 0.2 0.0 0.2 0.5 0.2 0.1 0.9 0.0 0.3 81.3 79.2 87.9 95.1 79.5 88.5 97.4 99.8 99.0 105.0 89.4 97.2 12.8 41.7 148.1 25.8 2.6 26.4 17.2 84.5 6.2 54.6 11.5 7.9 49.7 28.6 79.4 7.3 16.7 7.5 5.7 210.1 17.6 116.7 281.3 7.3 8.0 39.8 106.3 97.0 11.1 60.9 46.8 37.3 46.4 4.8 1.3 2.7 49.2 77.3 59.3 48.8 12.0 62.7 120.1 3.7 22.3 1031.8 226.5 7.9 83.6 2.8 2.3 287.6 10.3 4.5 9.7 57.2 132.7 386.3 4.2 14.4 22.8 8.2 186.5 69.5 26.3 107.2 56.4 20.2 16.7 33.6 28.4 13.5 7.1 83.4 65.5 25.3 AMN amnionless ENSG00000166126 "Amnion associated transmembrane protein" Q9BXJ7 14 102922663-102933596 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protein transport, Transport" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 83.5;kidney: 39.8;liver: 37.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 672.6;Intestinal goblet cells: 283.9;Paneth cells: 724.4;Proximal enterocytes: 2014.8;Proximal tubular cells: 348.9;Undifferentiated cells: 272.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.2;CACO-2: 8.1;Hep G2: 9.9;U-698: 3.4" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA000817 Approved "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA000817: AB_1078146" "unprognostic (2.02e-2)" "unprognostic (1.67e-1)" "unprognostic (3.94e-3)" "unprognostic (7.39e-3)" "unprognostic (9.32e-2)" "unprognostic (1.88e-3)" "unprognostic (8.68e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (2.97e-2)" "unprognostic (7.57e-2)" "unprognostic (2.43e-2)" "prognostic favorable (9.62e-5)" "unprognostic (8.02e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (1.66e-1)" 1.4 0.0 0.1 1.1 0.2 0.1 0.5 0.1 0.2 1.5 0.0 33.0 43.5 0.1 0.0 5.6 1.1 1.9 0.0 0.2 0.1 39.8 37.8 1.7 0.1 0.3 0.1 0.1 0.7 0.0 0.5 0.0 0.3 0.7 3.0 0.0 1.2 0.0 0.0 2.3 83.5 0.1 0.1 0.5 8.0 0.8 0.1 0.1 0.8 0.0 0.0 0.3 2.5 0.3 0.3 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 8.1 0.1 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 9.9 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.1 0.7 1.2 0.0 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.1 0.7 0.2 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.2 0.2 0.1 0.3 0.1 0.3 0.1 0.1 0.3 0.2 9.6 0.5 0.7 18.0 13.4 23.4 1.3 12.0 3.3 13.1 2.0 1.5 140.2 6.1 20.2 0.0 2.7 4.7 672.6 33.2 1.8 4.8 8.2 1.1 0.6 19.2 0.8 0.1 0.7 4.1 0.9 61.7 10.5 4.5 1.9 0.4 52.6 0.6 1.7 0.1 283.9 6.1 1.6 2.3 6.3 0.6 3.1 7.2 0.0 0.1 0.2 1.0 0.0 0.1 11.1 724.4 0.7 4.5 28.1 2014.8 348.9 4.5 1.2 0.0 0.5 0.9 21.2 25.7 17.1 20.9 1.4 5.2 0.4 272.4 65.7 ANK1 "ANK, SPH1" ENSG00000029534 "Ankyrin 1" P16157 8 41653220-41896762 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 993.4;tongue: 629.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 164.7;Cone photoreceptor cells: 87.6;Erythroid cells: 250.2;Inhibitory neurons: 176.8;Skeletal myocytes: 51.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory B-cell: 9.2;naive B-cell: 7.8;plasmacytoid DC: 3.4" "Group enriched" "Detected in many" 4 "B-cells: 9.2;dendritic cells: 3.4" "Group enriched" "Detected in many" 4 "HEL: 125.2;K-562: 134.3;RH-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004842, HPA056953" Supported Supported "Intracellular and membrane" NA NA 4200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA004842: AB_1844827, HPA056953: AB_2683284" "unprognostic (1.05e-1)" "unprognostic (1.30e-1)" "unprognostic (4.22e-3)" "unprognostic (2.31e-3)" "unprognostic (1.76e-7)" "unprognostic (2.03e-1)" "unprognostic (2.15e-1)" "unprognostic (2.52e-1)" "unprognostic (2.95e-1)" "unprognostic (3.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-1)" "unprognostic (1.40e-1)" "unprognostic (3.86e-1)" "unprognostic (4.65e-2)" "unprognostic (1.40e-1)" "unprognostic (1.04e-1)" 1.8 1.1 0.4 1.6 2.0 95.2 1.0 34.1 17.3 0.3 0.0 0.5 1.5 0.1 0.1 8.7 0.4 0.8 98.0 0.3 12.5 0.6 0.3 0.7 4.4 26.8 32.6 0.3 0.8 62.1 1.1 2.1 27.1 4.2 0.2 6.3 8.1 0.7 993.4 0.6 0.9 0.3 10.6 2.2 4.4 0.6 8.4 0.7 0.6 629.0 4.0 1.8 0.5 5.4 0.0 16.8 0.5 0.0 0.2 2.9 0.0 4.9 32.8 1.5 0.7 0.1 0.0 7.7 1.5 3.5 0.6 2.8 0.8 0.5 0.7 3.2 0.1 125.2 0.7 0.0 0.1 0.3 0.4 4.2 0.6 0.4 0.0 0.7 0.1 0.0 134.3 2.8 2.1 0.3 0.0 1.6 1.7 0.1 0.1 0.9 160.2 0.8 0.7 0.5 2.2 1.4 0.1 2.3 0.0 5.9 2.0 3.2 0.8 0.5 0.9 27.6 0.2 0.0 0.2 4.7 2.9 0.0 0.0 1.5 0.2 0.0 0.1 0.0 0.4 9.2 0.3 0.4 0.1 7.8 0.0 0.0 0.4 0.1 0.0 3.4 1.0 0.7 0.4 2.0 34.1 17.3 0.3 12.5 26.8 32.6 27.1 10.6 8.4 5.4 5.5 0.0 0.0 1.3 8.3 0.6 1.4 2.2 0.6 15.4 0.3 0.1 164.7 0.0 1.0 0.0 87.6 1.1 0.2 0.1 1.9 0.1 7.0 0.1 0.1 4.6 1.2 250.2 12.9 0.0 0.5 2.9 5.6 0.5 0.0 2.2 0.4 0.1 19.7 3.3 176.8 0.7 2.0 0.8 3.7 6.3 0.3 2.6 0.0 3.7 0.4 1.0 0.0 7.1 2.0 1.1 1.2 0.4 5.7 1.3 0.1 0.3 0.6 5.5 0.0 51.6 5.7 0.2 1.0 0.1 0.0 0.4 1.7 0.1 0.0 1.8 ANKRD26 "KIAA1074, THC2" ENSG00000107890 "Ankyrin repeat domain 26" Q9UPS8 10 26973793-27100494 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 130.6;Cone photoreceptor cells: 200.1;Excitatory neurons: 136.8;Inhibitory neurons: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA040654, HPA041460" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "HPA040654: AB_10795370, HPA041460: AB_10795120" "unprognostic (1.92e-1)" "unprognostic (3.41e-1)" "unprognostic (2.99e-1)" "unprognostic (1.46e-1)" "unprognostic (1.02e-1)" "unprognostic (2.09e-2)" "unprognostic (1.86e-5)" "unprognostic (2.96e-2)" "unprognostic (1.01e-1)" "unprognostic (4.08e-2)" "unprognostic (1.53e-2)" "unprognostic (1.03e-2)" "unprognostic (2.53e-3)" "unprognostic (5.35e-2)" "unprognostic (1.04e-2)" "unprognostic (1.99e-2)" "unprognostic (2.99e-1)" 2.3 2.6 4.7 1.6 5.4 1.5 3.8 5.9 8.6 3.9 5.0 2.5 1.7 3.3 3.0 2.0 3.0 2.0 4.1 4.4 4.0 2.7 2.8 1.9 3.5 4.7 3.8 4.0 2.6 4.0 4.6 3.2 2.7 2.6 2.8 10.0 2.3 2.5 6.7 2.5 2.0 2.5 2.8 2.5 2.2 4.0 4.9 3.1 2.7 7.5 2.2 2.2 2.7 5.8 7.7 5.4 9.8 3.7 6.1 6.7 3.4 10.1 3.7 9.2 8.5 5.2 5.1 17.9 3.1 4.7 6.5 8.1 9.6 4.7 11.0 7.4 7.2 1.1 7.9 7.9 4.5 4.5 1.2 4.7 2.9 9.5 3.2 7.5 8.4 5.5 14.8 4.8 9.3 4.3 5.5 2.8 3.9 2.8 3.5 6.6 13.8 4.3 5.7 3.1 8.5 4.7 9.6 2.0 8.1 7.1 8.5 3.1 7.6 7.7 5.2 9.9 5.7 1.9 2.6 11.7 7.3 9.9 3.5 1.0 0.2 0.2 0.2 0.1 0.7 1.2 0.4 0.4 0.3 0.6 1.6 0.5 0.1 1.6 0.1 2.1 0.4 0.2 4.7 5.4 5.9 8.6 4.4 4.0 4.7 3.8 2.7 2.8 4.9 5.8 19.5 22.4 28.8 130.6 14.3 4.2 7.6 9.0 8.6 77.8 13.5 17.7 70.9 7.2 19.4 3.7 200.1 24.8 8.6 8.3 5.9 14.5 19.0 47.7 38.6 20.4 20.9 6.3 136.8 13.1 13.1 21.3 8.2 16.5 5.1 43.5 13.6 8.3 11.9 79.1 185.9 9.3 10.2 5.7 5.4 6.4 30.4 11.8 3.6 45.0 12.4 45.0 18.6 87.0 67.2 11.3 4.2 27.1 7.8 5.3 12.1 5.6 49.5 117.9 32.9 30.1 15.6 60.7 57.2 8.9 8.0 13.7 12.9 46.1 14.6 5.0 ANO6 "DKFZp313M0720, TMEM16F" ENSG00000177119 "Anoctamin 6" Q4KMQ2 12 45215987-45482280 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038958 Approved Approved "Plasma membrane,Cytosol" NA NA 47000 "Cluster 14: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 32: U-937 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA038958: AB_10672835" "prognostic unfavorable (7.56e-5)" "prognostic unfavorable (3.82e-4)" "unprognostic (2.16e-1)" "unprognostic (1.75e-2)" "unprognostic (1.29e-1)" "unprognostic (9.82e-3)" "unprognostic (7.43e-2)" "unprognostic (3.01e-3)" "unprognostic (7.55e-2)" "unprognostic (2.84e-3)" "unprognostic (1.41e-3)" "unprognostic (3.02e-1)" "unprognostic (2.68e-2)" "unprognostic (1.26e-3)" "unprognostic (1.26e-1)" "unprognostic (4.20e-2)" "unprognostic (1.28e-1)" 86.4 25.9 7.4 16.8 8.0 9.8 27.5 7.9 8.4 28.9 13.8 29.9 36.2 38.9 25.6 25.0 27.2 31.6 27.7 7.2 10.5 36.2 56.9 40.2 13.4 10.4 8.5 56.6 25.3 58.8 6.9 50.5 10.1 29.9 15.0 3.6 25.4 37.1 56.0 12.0 51.4 48.4 9.0 16.0 13.8 11.8 9.1 24.9 13.2 46.3 12.8 35.0 16.0 9.3 41.5 44.3 25.7 35.4 119.1 61.7 97.4 57.4 72.5 38.4 36.3 71.9 61.5 21.1 52.2 92.0 34.9 54.0 24.1 32.3 45.6 31.4 16.9 25.0 17.8 62.1 37.8 39.5 19.4 51.7 31.9 33.0 48.7 95.4 52.6 44.5 19.3 34.0 42.7 11.2 41.5 13.2 28.6 0.0 18.0 23.4 33.3 24.4 36.9 63.1 11.7 39.9 59.9 36.8 27.9 67.7 43.3 62.8 70.6 41.2 26.1 41.8 29.3 18.3 21.5 25.8 37.3 122.8 33.4 3.1 5.9 1.4 2.4 6.9 2.5 1.4 2.2 2.0 5.5 1.2 2.0 1.3 0.6 2.3 7.1 2.7 3.0 4.2 7.4 8.0 7.9 8.4 7.2 10.5 10.4 8.5 10.1 9.0 9.1 9.3 65.1 60.9 11.8 54.9 10.0 30.5 20.3 27.7 23.3 1.1 23.0 18.7 23.4 30.0 21.5 18.4 0.0 34.0 14.5 2.5 3.9 38.4 1.3 13.3 32.1 37.5 8.4 8.0 49.8 37.4 28.0 44.2 21.4 26.0 12.7 20.2 52.5 88.3 19.9 0.0 49.0 11.5 12.2 56.3 22.9 3.5 51.3 46.0 17.8 68.4 29.1 8.2 15.5 110.6 3.0 73.3 10.0 40.6 12.2 29.5 70.3 23.4 16.5 0.3 39.5 45.9 52.1 3.5 4.3 25.1 22.0 24.6 17.3 6.7 14.6 30.5 ASXL1 KIAA0978 ENSG00000171456 "ASXL transcriptional regulator 1" Q8IXJ9 20 32358330-32439319 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor" "Cancer-related genes, Craniosynostosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064156 Approved Nucleoplasm,Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "HPA064156: AB_2685200" "unprognostic (1.49e-1)" "unprognostic (5.97e-2)" "unprognostic (8.36e-2)" "prognostic unfavorable (2.86e-4)" "unprognostic (6.69e-2)" "prognostic favorable (9.16e-4)" "unprognostic (2.01e-3)" "unprognostic (2.89e-1)" "unprognostic (1.49e-1)" "unprognostic (1.38e-1)" "unprognostic (4.32e-2)" "unprognostic (3.21e-2)" "unprognostic (1.84e-3)" "unprognostic (5.47e-2)" "unprognostic (1.90e-1)" "unprognostic (4.82e-2)" "unprognostic (1.06e-1)" 31.6 24.6 13.4 18.1 14.4 36.9 30.5 15.0 14.4 30.6 20.2 31.6 12.2 26.8 15.6 17.2 28.6 13.7 21.8 14.1 15.6 28.7 32.8 36.0 24.0 15.8 14.2 32.3 32.9 13.1 19.2 17.3 13.8 24.8 13.2 19.7 21.0 13.3 30.1 23.2 27.8 18.4 13.8 35.0 24.7 37.2 15.1 27.4 32.0 16.4 25.0 26.4 24.2 17.1 59.2 33.6 52.7 28.2 23.6 28.6 45.6 35.4 33.0 64.1 48.6 99.8 35.2 54.4 24.5 47.3 62.2 39.5 45.3 37.8 53.2 70.6 24.1 88.9 53.6 55.7 21.6 38.5 36.1 32.4 25.1 46.1 35.6 33.3 37.4 45.3 45.2 29.1 31.9 18.4 51.7 30.3 12.9 27.7 38.9 30.8 62.1 24.8 27.1 28.4 23.7 38.2 68.9 23.5 31.7 27.9 32.7 27.0 39.9 69.1 59.4 32.3 43.2 33.9 38.6 39.3 34.0 100.2 27.8 0.1 0.6 1.0 2.6 0.5 2.5 4.8 3.6 3.9 0.8 3.3 3.5 4.0 0.5 1.5 0.6 2.7 9.0 1.5 13.4 14.4 15.0 14.4 14.1 15.6 15.8 14.2 13.8 13.8 15.1 17.1 92.3 51.3 35.5 54.9 63.3 40.0 51.8 8.6 50.7 21.4 52.9 48.6 19.8 15.7 17.9 27.6 52.1 18.0 55.2 18.8 25.4 13.5 97.8 59.4 80.1 65.6 7.2 40.8 61.4 12.6 16.5 49.8 30.5 86.2 18.3 57.7 41.0 34.7 21.3 18.5 80.3 14.1 16.2 21.2 42.2 84.9 25.4 33.5 78.2 75.9 16.7 11.6 20.6 78.4 125.9 15.6 13.7 14.7 94.6 49.6 29.9 31.7 20.8 30.7 6.6 96.7 62.7 31.0 16.1 34.6 30.5 5.9 67.2 36.4 17.5 40.5 ATRX "JMS, MRX52, RAD54, XH2, XNP" ENSG00000085224 "ATRX chromatin remodeler" P46100 X 77504880-77786233 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001906, CAB009372, HPA064684, CAB068176" Supported Supported "Nuclear bodies" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" "CAB009372: AB_2061023, CAB068176: AB_2665665, HPA001906: AB_1078249, HPA064684: AB_2685321" "unprognostic (1.77e-2)" "unprognostic (1.55e-1)" "unprognostic (6.65e-2)" "unprognostic (4.37e-2)" "unprognostic (1.67e-1)" "unprognostic (9.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.15e-2)" "unprognostic (6.04e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (5.80e-2)" "unprognostic (5.14e-3)" "unprognostic (1.50e-1)" "unprognostic (6.19e-2)" "unprognostic (1.76e-2)" "unprognostic (2.24e-1)" 18.0 15.9 17.3 17.6 20.4 29.9 18.1 32.9 20.4 18.0 21.4 12.7 11.2 21.2 14.8 13.3 11.8 14.7 15.5 19.2 19.8 16.9 13.2 13.4 22.6 15.0 20.1 24.9 13.4 23.2 8.5 16.6 16.6 19.2 13.5 26.8 14.0 14.8 19.1 15.6 10.9 15.6 16.4 22.8 16.5 6.6 22.6 25.7 20.0 26.9 18.6 14.1 9.9 19.7 36.0 55.1 60.1 45.0 31.8 38.1 21.2 29.4 27.3 21.8 25.9 19.6 30.7 48.5 29.9 32.5 39.9 30.0 44.6 18.1 37.5 27.3 30.8 29.3 67.2 16.2 16.1 38.4 10.2 25.5 20.2 32.2 30.4 29.4 41.9 30.3 34.9 53.3 29.3 27.6 30.2 25.0 42.0 17.6 42.5 48.6 76.3 26.0 25.6 46.4 33.1 55.5 60.5 23.1 21.9 37.2 18.6 20.8 55.8 32.8 76.1 34.4 21.0 16.3 52.9 42.1 23.0 30.9 27.8 44.0 10.5 22.7 26.0 13.3 25.2 31.2 24.0 20.9 8.1 32.4 24.6 20.1 33.2 23.2 20.0 20.7 22.2 9.7 17.3 20.4 32.9 20.4 19.2 19.8 15.0 20.1 16.6 16.4 22.6 19.7 201.0 160.3 230.1 157.4 176.6 92.4 112.2 71.3 114.9 220.1 87.8 86.7 277.8 60.1 101.5 71.7 212.7 72.2 176.9 49.0 23.5 91.8 4.7 103.1 195.5 162.8 126.8 105.8 197.8 83.1 51.0 134.3 114.2 137.3 113.1 261.4 97.8 56.7 70.9 158.2 246.9 78.0 69.2 87.0 101.6 12.7 162.4 113.1 62.2 195.8 149.0 112.3 183.4 202.5 237.1 92.0 47.6 208.0 183.9 120.8 49.2 37.2 102.6 245.4 92.1 174.7 160.0 19.8 52.8 78.7 84.4 59.8 158.0 312.4 73.3 112.0 B2M ENSG00000166710 Beta-2-microglobulin P61769 15 44711487-44718851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Immunity "Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 31919.3;NK-cells: 24726.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002572, HPA006361" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1790000000 2100000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus, Plasma membrane" Cytosol "CAB002572: AB_563434, HPA006361: AB_1078278" "unprognostic (9.45e-2)" "unprognostic (5.63e-2)" "unprognostic (3.02e-1)" "unprognostic (8.14e-2)" "unprognostic (1.18e-1)" "unprognostic (4.82e-2)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (2.44e-3)" "unprognostic (2.02e-2)" "unprognostic (4.77e-2)" "unprognostic (2.39e-1)" "unprognostic (5.25e-2)" "unprognostic (1.97e-2)" "unprognostic (2.17e-2)" 3160.2 3214.7 697.6 5686.5 705.1 7839.2 2606.9 711.8 1145.0 2539.9 789.6 5139.0 5180.7 2192.2 1735.6 2283.9 1648.3 4948.8 2327.2 651.0 769.9 2462.6 6206.2 6159.2 9311.8 889.5 763.2 1945.7 1310.9 1940.5 318.4 3502.0 815.3 2345.0 5593.5 139.3 5657.1 1784.5 931.7 3015.6 5693.3 2545.3 838.3 7896.1 4878.2 615.6 771.9 4217.4 2340.8 2026.5 5333.4 5753.1 549.4 909.5 1735.4 378.9 226.0 633.6 4348.7 4719.4 1662.5 2045.5 4961.9 3609.7 6561.4 425.3 5417.9 554.8 2567.9 1948.8 2410.2 2537.0 497.2 878.7 1226.2 4762.2 435.9 2956.9 2263.6 600.3 3609.3 2074.5 3328.6 2735.9 609.8 1075.7 1044.4 2442.6 1884.1 965.4 611.9 3649.1 2195.5 476.9 1518.4 3213.8 206.5 629.8 1014.3 2240.2 1926.6 4789.2 2425.5 3486.4 254.1 179.1 1288.4 1571.2 1338.5 394.3 655.3 6180.6 2548.7 4531.4 676.5 5389.2 2193.3 4771.7 7118.6 1683.1 5384.6 3783.6 2567.3 48105.4 18117.1 33178.9 20639.1 17775.0 20836.8 15768.0 23783.0 22245.1 9978.8 11988.4 17122.9 22791.8 50453.6 18779.6 19034.9 12052.6 29659.1 56957.2 697.6 705.1 711.8 1145.0 651.0 769.9 889.5 763.2 815.3 838.3 771.9 909.5 12048.3 3387.8 3505.1 28.7 8472.8 7843.7 3197.1 8420.8 1628.8 33.3 2399.5 2015.2 1068.8 3593.1 5347.4 2100.3 27.1 1354.6 14028.8 8753.6 1038.9 13898.6 43.1 2073.7 2414.0 8385.6 2266.0 2087.2 7.3 9034.5 4397.5 3691.1 1981.7 2282.2 3029.5 1270.6 6835.7 3832.6 11985.7 5.0 22.0 5982.6 8701.4 12536.8 14507.0 158.8 3018.0 10687.9 6744.8 368.2 31919.3 322.0 24726.3 95.0 129.2 10115.7 7085.6 1688.8 11026.6 5300.4 18327.7 3122.5 8367.9 52.5 4016.7 2055.2 4107.1 64.2 72.1 1541.4 8619.8 804.8 14266.2 3229.8 3063.4 8248.6 BPGM ENSG00000172331 "Bisphosphoglycerate mutase" P07738 7 134646811-134679816 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Congenital erythrocytosis, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 87.3" "Group enriched" "Detected in all" 4 "Distal tubular cells: 129.1;Erythroid cells: 456.6;Syncytiotrophoblasts: 368.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 118.2;RT4: 186.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016493, HPA028735" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA 81000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 15: RT4 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA016493: AB_1845414, HPA028735: AB_10600791" "unprognostic (2.56e-1)" "prognostic favorable (7.95e-4)" "unprognostic (3.19e-1)" "unprognostic (3.94e-1)" "unprognostic (1.78e-1)" "unprognostic (5.22e-2)" "unprognostic (3.81e-3)" "unprognostic (1.96e-1)" "unprognostic (7.74e-2)" "unprognostic (4.67e-3)" "unprognostic (7.42e-2)" "unprognostic (5.69e-2)" "prognostic favorable (1.54e-8)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (2.73e-1)" "unprognostic (3.78e-2)" 11.4 12.6 16.3 9.1 17.1 87.3 12.4 17.9 20.5 12.5 15.8 12.9 8.4 9.6 18.5 26.9 8.5 12.9 13.5 16.5 19.0 35.1 13.1 14.0 11.1 17.9 17.8 7.1 8.4 35.3 18.1 47.0 18.2 13.5 10.0 19.9 17.8 17.9 37.8 10.7 8.0 12.1 19.6 12.5 11.9 14.7 17.7 16.3 11.9 27.0 26.2 39.0 17.2 18.5 14.0 16.3 21.7 29.6 24.3 14.4 21.9 41.3 49.9 15.7 23.2 6.5 18.5 17.1 12.0 23.2 30.9 11.2 23.3 22.7 27.6 118.2 19.9 9.8 15.4 7.8 16.7 18.8 12.4 14.2 20.0 29.7 16.0 24.0 58.0 20.8 28.8 20.9 37.8 6.6 30.7 26.0 22.7 27.7 15.3 23.2 15.5 12.4 36.1 186.8 18.7 31.1 19.3 23.1 21.7 23.1 15.1 11.8 44.7 25.1 6.0 33.7 33.9 33.9 41.2 21.5 43.3 17.7 43.7 61.1 16.4 48.9 23.3 22.2 16.7 19.3 15.0 20.7 17.5 18.9 20.7 21.1 30.2 18.5 23.0 11.4 21.1 23.6 16.3 17.1 17.9 20.5 16.5 19.0 17.9 17.8 18.2 19.6 17.7 18.5 17.6 9.6 25.5 6.5 15.7 39.0 18.5 60.6 10.8 19.2 15.9 18.7 25.0 18.6 52.3 27.6 2.1 44.5 43.0 5.0 129.1 45.9 3.4 10.0 7.0 18.8 13.1 456.6 8.0 18.2 32.7 17.0 4.1 8.5 24.7 6.6 10.0 4.7 15.1 20.2 9.3 4.6 36.7 11.7 10.5 7.2 10.2 11.8 23.2 5.6 15.7 25.6 47.4 7.5 11.6 49.0 4.6 12.0 14.2 26.0 5.5 68.8 50.5 13.5 6.6 12.0 22.1 33.9 21.8 13.5 13.2 368.9 25.0 7.8 4.8 19.2 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1 DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 42.5;Granulosa cells: 38.2;Spermatocytes: 105.8;Spermatogonia: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3" "Group enriched" "Detected in all" 6 "dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 3.1 1.8 4.2 7.5 7.2 13.0 3.6 4.7 5.2 2.7 2.7 6.8 3.2 3.1 2.2 4.0 3.7 1.9 3.0 3.6 4.1 2.0 5.6 3.2 10.3 5.6 5.0 2.8 2.8 5.9 2.8 3.8 6.0 2.4 7.4 8.2 3.2 1.6 4.2 6.0 5.1 3.9 3.7 3.9 3.6 13.0 5.5 14.5 7.8 3.7 11.2 2.8 2.4 10.8 44.1 69.1 37.8 30.1 6.0 13.4 36.6 50.6 21.5 41.9 39.3 42.3 33.4 100.8 9.1 19.0 49.0 49.5 51.9 28.3 69.5 46.9 38.0 48.1 54.0 37.1 1.3 86.0 39.9 3.8 4.5 63.1 20.0 10.6 22.3 46.6 73.7 42.2 39.7 30.0 72.0 27.8 20.5 29.1 18.7 49.0 79.8 40.8 15.4 42.1 25.8 27.4 38.8 12.5 19.4 25.5 33.9 39.6 13.8 37.2 29.6 49.0 53.2 20.1 51.2 75.5 29.6 49.6 39.4 6.8 14.7 2.2 1.5 4.7 1.5 1.2 1.5 1.2 10.9 2.1 1.3 1.5 11.3 1.5 2.0 1.7 0.5 17.5 4.2 7.2 4.7 5.2 3.6 4.1 5.6 5.0 6.0 3.7 5.5 10.8 5.0 0.0 2.8 9.4 5.8 2.9 4.5 1.9 1.2 10.3 4.4 5.2 10.1 5.7 3.5 1.8 22.9 12.8 8.1 6.2 0.0 3.0 11.9 14.0 6.3 4.7 0.0 42.5 3.0 1.1 18.2 7.4 6.1 4.2 8.2 38.2 5.3 18.3 10.1 11.8 4.4 7.5 0.0 3.9 2.8 8.0 2.5 6.4 0.0 4.7 4.9 2.4 5.2 3.0 18.7 1.7 2.4 1.5 16.6 2.3 1.1 1.0 10.0 22.8 6.6 13.7 5.5 105.8 73.5 8.2 2.3 4.0 4.7 9.7 12.7 3.4 BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2 DNA repair associated" P51587 13 32315086-32400268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 115.4;Spermatogonia: 85.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.0 1.3 0.0 5.8 0.5 0.0 0.0 0.2 0.2 0.7 0.5 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.3 0.3 2.1 0.1 0.1 0.1 0.1 0.0 0.0 1.0 0.1 0.1 0.8 0.0 0.2 0.0 0.0 0.7 0.5 0.3 0.1 0.9 0.6 2.7 0.2 3.1 0.2 0.0 2.0 0.5 0.2 0.1 4.7 4.0 6.0 5.0 0.6 1.4 7.0 4.8 3.1 5.5 5.0 10.6 6.0 15.9 3.2 2.1 7.6 6.1 5.5 2.9 10.5 10.5 3.1 10.3 2.5 3.5 0.1 15.4 4.9 0.2 0.0 10.3 6.9 0.4 4.5 8.1 7.0 5.5 6.4 5.1 11.8 8.3 8.3 4.9 2.3 11.4 17.3 3.0 1.4 5.4 2.4 4.6 5.9 2.4 2.2 2.2 2.9 7.3 1.3 6.3 6.8 7.0 6.7 2.0 3.3 8.0 2.7 5.7 5.8 0.0 0.3 1.5 0.5 0.7 0.1 1.7 0.4 0.4 0.3 2.2 0.5 0.4 0.8 0.5 0.8 3.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 4.4 9.6 2.6 0.0 12.4 2.5 3.3 2.5 2.2 0.0 4.3 3.3 1.9 0.0 1.8 0.0 0.0 14.1 10.5 4.8 0.0 2.5 5.2 4.4 6.3 5.5 1.2 29.5 0.7 1.6 12.7 5.8 10.7 4.6 3.8 26.9 1.4 0.8 9.5 0.0 0.5 4.4 0.0 7.5 11.0 4.4 2.1 14.4 3.6 4.7 20.1 0.3 0.0 0.0 0.6 1.2 1.8 1.2 27.8 1.2 1.0 0.6 2.9 0.0 13.1 8.3 5.3 115.4 85.6 8.0 1.3 5.5 7.9 4.2 7.8 2.3 BRIP1 "BACH1, FANCJ, OF" ENSG00000136492 "BRCA1 interacting protein C-terminal helicase 1" Q9BX63 17 61679139-61863528 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.2;lymphoid tissue: 5.9;testis: 7.0" "Group enriched" "Detected in many" 12 "Early spermatids: 186.2;Late spermatids: 194.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005474 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear membrane" "HPA005474: AB_2667333" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "prognostic favorable (3.45e-5)" "unprognostic (6.85e-4)" "unprognostic (3.09e-1)" "prognostic favorable (3.62e-4)" "unprognostic (2.60e-3)" "unprognostic (5.60e-2)" "unprognostic (5.66e-3)" "unprognostic (6.71e-2)" "unprognostic (1.50e-3)" "unprognostic (2.75e-2)" "unprognostic (3.41e-12)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" "unprognostic (3.96e-2)" "unprognostic (3.62e-3)" 0.3 0.3 0.8 1.7 0.6 7.2 0.9 1.3 0.9 0.4 0.0 1.7 2.0 0.8 0.4 1.5 0.3 0.6 0.1 0.5 0.2 0.3 1.6 0.4 2.8 0.3 0.0 1.1 0.3 0.1 0.0 0.8 0.4 0.4 1.9 0.5 0.4 0.2 0.1 2.0 1.9 0.9 0.0 0.7 0.9 7.0 0.2 5.9 0.3 0.1 3.3 0.7 0.6 0.8 26.6 9.4 25.0 14.1 0.9 2.1 5.5 23.6 13.3 24.6 31.8 9.5 8.0 14.9 5.2 4.9 7.7 9.2 12.8 4.5 33.3 3.8 15.8 15.5 14.4 10.5 0.2 20.3 8.8 0.6 0.4 20.2 5.1 3.4 5.0 14.8 11.6 10.5 14.4 88.9 32.5 6.7 5.3 5.9 7.3 19.7 50.1 7.1 3.0 12.8 10.0 24.2 9.4 3.0 3.3 9.1 8.3 7.3 4.5 36.9 26.5 13.5 26.6 6.3 13.3 16.6 7.3 9.3 8.8 1.0 0.1 0.4 0.1 0.0 0.1 0.5 0.3 0.1 0.1 0.6 0.4 0.2 0.3 0.1 0.1 0.1 1.0 0.1 0.8 0.6 1.3 0.9 0.5 0.2 0.3 0.0 0.4 0.0 0.2 0.8 0.2 0.0 0.5 1.0 1.6 2.3 1.3 0.8 0.6 0.3 1.1 1.8 0.6 0.0 4.0 0.0 0.0 2.0 2.0 1.8 0.0 0.3 186.2 0.7 1.7 0.8 0.0 7.4 4.6 0.2 3.0 2.0 2.0 1.6 0.0 15.5 0.4 3.4 1.7 0.0 3.3 1.8 0.0 0.8 1.1 194.1 1.2 1.0 3.6 2.8 0.6 0.2 1.0 1.5 1.0 0.8 0.1 1.2 4.8 0.4 1.4 0.2 0.8 0.2 0.0 2.5 1.8 12.1 6.0 2.9 0.4 0.3 2.3 2.1 4.7 0.7 C3 "ARMD9, C3a, C3b, CPAMD1" ENSG00000125730 "Complement C3" P01024 19 6677704-6730562 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Fatty acid metabolism, Immunity, Inflammatory response, Innate immunity, Lipid metabolism" "Age-related macular degeneration, Disease variant, FDA approved drug targets, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 4761.3" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 4512.2" "Cancer enriched" "Detected in all" 5 "liver cancer: 1213.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "non-classical monocyte: 13.3" "Lineage enriched" "Detected in many" 4 "monocytes: 13.3" "Group enriched" "Detected in many" 7 "BJ hTERT+: 357.8;EFO-21: 738.6;Hep G2: 795.3;HSkMC: 534.8;SiHa: 209.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003563, CAB004209, HPA020432" Enhanced "Secreted to blood" NA NA 1260000000000 200000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB004209: AB_627277, HPA003563: AB_1847117, HPA020432: AB_1847118" "unprognostic (3.26e-3)" "unprognostic (3.91e-1)" "unprognostic (3.92e-1)" "unprognostic (5.98e-3)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "prognostic favorable (8.11e-4)" "unprognostic (1.99e-1)" "unprognostic (9.26e-2)" "unprognostic (5.80e-2)" "unprognostic (8.12e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.63e-2)" "unprognostic (2.49e-2)" "unprognostic (6.03e-3)" "unprognostic (3.88e-1)" 585.2 286.5 46.0 194.3 53.7 1.5 213.9 47.8 46.0 237.5 31.5 128.9 22.9 82.9 41.1 76.4 350.3 354.9 221.6 36.5 81.8 51.4 4761.3 176.0 68.2 143.3 99.2 228.1 182.7 17.9 21.8 17.7 116.4 35.4 76.5 11.7 155.6 57.4 36.6 51.4 156.4 123.0 89.9 7.1 107.9 41.1 103.4 34.1 92.4 52.0 126.4 363.3 101.3 121.9 65.0 23.0 0.0 0.1 10.8 36.0 74.7 5.2 357.8 6.8 12.6 3.6 49.5 1.9 738.6 0.3 54.2 46.6 0.2 43.1 6.9 24.0 0.5 3.1 31.2 795.3 16.3 6.2 9.1 534.8 12.8 60.8 27.3 9.5 0.0 0.0 2.1 0.8 0.2 1.0 0.6 1.6 1.5 0.7 0.1 0.4 5.0 0.3 32.1 6.2 0.5 0.5 209.5 0.1 0.5 0.1 17.2 8.8 3.5 5.7 7.4 4.8 3.6 1.6 4.8 4.5 75.1 4.5 0.3 1.7 1.3 0.6 0.3 2.5 0.2 0.5 0.2 0.1 0.7 0.5 0.2 0.2 3.0 1.3 13.3 0.5 0.1 0.9 46.0 53.7 47.8 46.0 36.5 81.8 143.3 99.2 116.4 89.9 103.4 121.9 36.4 76.9 473.9 0.7 29.4 27.5 14.7 141.5 0.6 0.7 19.5 23.4 14.5 783.5 422.5 16.5 0.0 1.4 2.0 0.2 5.9 494.1 45.9 23.0 63.5 26.2 0.0 209.9 0.4 136.7 1.4 482.2 17.9 57.7 5.1 0.1 124.9 4512.2 34.4 0.0 0.5 0.9 20.3 164.5 44.8 97.5 226.2 45.1 35.6 70.3 14.6 1.2 0.0 0.5 0.6 376.4 0.2 10.9 3.9 13.3 1.9 53.6 177.5 4.6 6.6 20.1 49.1 4.0 7.7 5.2 21.9 2.7 15.0 0.1 0.4 38.2 CBLIF "GIF, IF, IFMH, INF, TCN3" ENSG00000134812 "Cobalamin binding intrinsic factor" P27352 11 59829273-59845499 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1859 "stomach 1: 1575.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "stomach cancer: 10.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039908, HPA040774" Enhanced "Secreted to digestive system" NA NA "Cluster 4: Stomach - Digestion" "HPA039908: AB_10796335, HPA040774: AB_10795626" "unprognostic (2.78e-4)" "unprognostic (1.04e-1)" "unprognostic (2.45e-1)" "unprognostic (3.59e-1)" "unprognostic (1.66e-1)" 0.8 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.6 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1575.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CD46 "MCP, MGC26544, MIC10, TLX, TRA2.10" ENSG00000117335 "CD46 molecule" P15529 1 207752054-207795513 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Complement pathway, Fertilization, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 296.7;eosinophil: 382.4;neutrophil: 401.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 401.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB010401, HPA016903" Enhanced Approved "Plasma membrane" NA NA 1000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "CAB010401: AB_2291289, HPA016903: AB_1846309" "unprognostic (1.42e-2)" "prognostic unfavorable (8.54e-5)" "unprognostic (3.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.28e-2)" "unprognostic (6.30e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "unprognostic (2.74e-1)" "unprognostic (8.79e-2)" "unprognostic (2.50e-1)" "unprognostic (6.78e-3)" "prognostic favorable (2.38e-4)" "unprognostic (1.76e-1)" "unprognostic (8.23e-2)" "unprognostic (1.49e-2)" 98.6 237.4 30.0 64.0 35.0 80.5 128.4 33.5 39.5 74.0 61.4 103.1 124.6 62.1 77.1 102.2 110.0 73.8 64.9 30.2 34.4 173.2 133.9 129.1 58.2 37.4 33.6 61.2 112.5 310.6 41.8 221.5 38.1 167.4 103.2 72.6 166.9 107.4 47.4 47.7 98.6 67.1 34.8 79.6 117.4 40.5 36.3 44.4 86.8 58.1 66.6 97.2 68.2 41.5 130.0 71.7 66.1 30.8 202.9 199.2 99.9 95.0 137.3 61.3 82.5 71.3 335.4 19.8 94.3 95.3 84.5 170.7 50.0 130.5 93.0 99.9 70.9 42.9 73.8 128.6 128.8 94.8 142.8 172.9 189.6 92.9 72.5 144.4 174.2 76.8 91.8 83.4 95.7 61.3 45.4 82.8 75.6 76.9 70.9 30.2 104.7 123.0 251.4 252.6 66.5 45.4 120.5 266.8 160.1 130.8 210.2 79.8 150.9 65.6 57.7 139.2 109.9 111.2 144.3 60.1 95.8 61.2 63.0 296.7 79.8 382.4 50.1 82.4 68.9 43.5 63.3 55.8 47.3 34.1 71.1 60.5 401.8 46.9 87.5 24.9 60.5 102.4 30.0 35.0 33.5 39.5 30.2 34.4 37.4 33.6 38.1 34.8 36.3 41.5 186.0 201.9 241.1 59.7 60.3 52.9 89.3 87.2 108.1 63.0 144.3 85.7 61.4 75.8 177.8 145.3 66.7 247.3 94.0 105.2 15.6 77.4 227.7 206.1 67.0 106.7 72.8 46.9 61.0 79.9 76.2 70.5 97.9 231.3 114.5 78.1 77.8 120.9 59.9 40.4 73.6 91.1 87.5 78.9 63.1 36.9 47.2 91.6 62.2 82.4 88.7 25.3 39.1 112.1 153.9 72.8 117.7 44.0 76.0 144.5 92.6 54.4 208.8 87.3 52.6 69.7 89.3 17.1 20.2 104.5 45.9 343.7 89.9 99.4 115.9 165.7 CDAN1 "CDA-I, CDAI" ENSG00000140326 "Codanin 1" Q8IWY9 15 42723544-42737128 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 19.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039404, HPA040787" Supported Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane" "HPA039404: AB_10673530, HPA040787: AB_2677137" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (5.79e-3)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" "unprognostic (7.71e-2)" "prognostic unfavorable (1.07e-4)" "unprognostic (7.17e-2)" "unprognostic (9.82e-2)" "unprognostic (1.24e-1)" "unprognostic (2.95e-2)" "unprognostic (1.26e-1)" "unprognostic (4.35e-3)" "unprognostic (2.05e-1)" "unprognostic (1.16e-1)" "unprognostic (9.20e-3)" "unprognostic (2.04e-1)" 4.0 5.0 2.1 3.6 2.2 8.1 4.3 4.3 3.1 7.7 3.2 4.5 2.8 5.9 4.4 4.1 6.1 2.5 2.9 2.1 0.9 3.2 4.0 3.5 4.2 3.0 1.5 11.3 4.8 3.5 5.1 3.2 2.7 6.9 2.5 2.6 5.4 3.5 4.2 4.9 4.2 2.8 0.7 4.6 4.5 6.3 1.4 5.2 5.1 2.8 3.4 5.8 5.6 2.6 8.1 5.4 7.2 10.4 6.3 5.4 8.6 10.4 4.3 9.9 7.2 13.6 4.2 3.9 11.2 5.8 9.7 15.5 7.7 4.7 2.9 9.9 7.2 14.5 10.3 5.3 4.7 10.8 13.2 7.4 5.2 6.3 4.5 6.1 7.6 13.0 18.9 5.7 8.2 4.5 8.4 14.2 3.6 7.7 8.5 11.9 9.0 3.4 3.1 7.9 5.9 6.8 8.2 11.3 1.7 4.6 8.6 15.9 5.6 10.4 9.2 8.6 12.1 11.2 12.7 8.7 5.4 15.8 8.6 1.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 2.1 2.2 4.3 3.1 2.1 0.9 3.0 1.5 2.7 0.7 1.4 2.6 2.0 0.0 3.7 4.6 2.4 1.9 2.0 1.5 1.8 3.3 3.2 1.8 2.2 2.8 1.5 7.3 4.2 3.0 2.6 1.9 0.0 1.5 0.4 2.0 2.8 2.3 4.8 1.7 7.6 1.8 1.6 2.9 3.6 2.0 1.3 9.0 3.9 3.6 2.1 1.7 6.3 1.6 4.1 2.5 0.9 1.2 4.4 1.6 0.0 4.7 1.5 4.5 2.1 5.5 3.8 1.6 0.5 4.9 2.5 2.3 2.2 1.3 1.9 4.7 19.7 3.4 2.4 5.4 2.1 2.8 1.3 2.2 2.5 4.6 2.6 1.7 CDIN1 "C15orf41, FLJ22851, HH114, MGC11326" ENSG00000186073 "CDAN1 interacting nuclease 1" Q9Y2V0 15 36579626-36810248 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 78.6;tongue: 34.5" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 97.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061023 Uncertain Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA061023: AB_2684417" "unprognostic (1.82e-1)" "unprognostic (1.14e-1)" "unprognostic (1.10e-2)" "unprognostic (4.92e-2)" "unprognostic (2.93e-3)" "unprognostic (2.27e-2)" "unprognostic (2.37e-2)" "unprognostic (2.02e-2)" "unprognostic (3.40e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-3)" "unprognostic (9.14e-2)" "unprognostic (3.74e-6)" "unprognostic (1.22e-2)" "unprognostic (4.54e-2)" "unprognostic (1.62e-4)" "unprognostic (1.58e-1)" 2.8 5.1 2.9 2.4 7.9 0.7 2.9 4.3 4.1 5.9 1.6 5.6 6.7 6.8 1.8 9.4 4.1 4.0 78.6 2.5 3.5 2.8 3.7 2.5 2.4 3.9 3.4 4.3 2.2 2.4 2.3 2.1 4.3 6.0 3.2 9.6 5.0 6.6 12.0 5.6 3.3 9.5 2.9 2.2 3.3 7.1 3.4 4.2 2.5 34.5 3.6 9.5 8.3 4.9 19.0 10.0 12.4 4.7 13.5 15.6 5.1 8.9 4.5 11.1 9.1 13.9 7.4 3.0 8.8 22.1 8.1 33.8 13.0 7.7 12.7 1.5 9.1 9.9 9.0 10.3 11.8 8.4 7.1 12.0 8.3 9.5 5.2 8.5 10.7 9.6 12.9 3.1 15.4 8.6 2.6 4.9 6.8 8.6 5.1 7.9 3.5 2.0 7.4 25.8 7.1 4.4 5.7 5.5 4.8 9.0 5.5 13.1 7.6 10.8 5.9 7.3 2.5 7.2 11.2 13.7 13.7 15.0 10.2 0.0 0.5 0.3 2.5 1.3 2.2 2.1 1.9 2.4 1.4 2.2 2.3 1.9 0.0 3.3 0.4 1.1 5.1 1.1 2.9 7.9 4.3 4.1 2.5 3.5 3.9 3.4 4.3 2.9 3.4 4.9 1.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.6 0.0 0.0 0.0 0.0 8.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 6.6 1.4 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 10.8 0.2 0.0 0.0 0.0 CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952084 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "liver: 2613.2" "Cell type enhanced" "Detected in many" "Ductal cells: 873.6;Exocrine glandular cells: 197.3;Hepatocytes: 284.0;Pancreatic endocrine cells: 318.0;Proximal enterocytes: 139.7" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 15.0;ASC TERT1: 23.0;EFO-21: 25.1;fHDF/TERT166: 14.1;HSkMC: 19.1;U-87 MG: 10.1" "Low region specificity" "Detected in all" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" NA NA 879000000 120000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favorable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" 143.7 18.0 3.6 32.8 3.6 0.1 28.5 3.4 9.9 16.3 3.9 22.3 28.1 8.2 14.2 24.1 53.7 0.8 42.6 3.7 3.4 58.7 2613.2 39.2 4.2 4.1 3.7 9.9 51.8 0.2 17.7 5.0 3.8 60.3 14.5 1.4 43.3 0.0 3.0 7.7 73.1 48.3 3.4 12.9 54.5 2.1 3.7 1.9 15.5 0.7 6.7 17.8 9.2 3.6 0.5 1.9 0.1 0.0 15.0 23.0 0.1 0.0 0.2 1.1 0.0 0.1 8.6 0.1 25.1 14.1 0.6 6.0 0.0 1.8 1.2 1.0 0.3 0.7 0.4 0.5 0.0 1.0 0.4 19.1 0.4 0.6 0.5 1.3 0.2 0.1 0.3 0.7 0.1 0.2 0.1 0.3 0.4 0.0 0.4 0.3 0.3 1.3 1.7 0.5 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 3.4 1.2 0.4 0.4 0.7 2.1 1.0 10.1 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 3.6 3.4 9.9 3.7 3.4 4.1 3.7 3.8 3.4 3.7 3.6 1.0 0.0 16.9 0.0 2.6 0.8 0.9 64.8 11.4 0.3 4.9 0.9 0.4 44.3 127.3 5.5 0.0 0.1 0.0 3.7 3.9 873.6 0.0 1.9 0.4 3.9 2.4 16.0 0.2 197.3 0.2 34.6 20.9 1.2 0.0 0.0 11.7 284.0 1.0 0.0 0.2 8.5 18.3 19.7 1.0 0.0 2.8 1.1 0.0 5.6 18.1 0.4 0.0 0.0 0.0 318.0 10.6 0.0 0.1 8.6 139.7 17.1 75.4 0.7 0.0 1.0 12.6 0.1 0.1 3.9 1.8 1.6 1.6 0.0 12.4 4.5 CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196652043-196747504 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 1676.3" "Group enriched" "Detected in many" 4 "Fibroblasts: 448.0;Hepatocytes: 1114.8;Leydig cells: 283.9" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 18.7" "Lineage enriched" "Detected in single" 26 "T-cells: 18.7" "Cell line enhanced" "Detected in many" "HHSteC: 123.1;HSkMC: 119.5;hTERT-RPE1: 374.9;RT4: 227.0" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" NA NA 396000000000 100000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: AB_2676271, HPA049176: AB_2680663, HPA053326: AB_2682113" "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" 125.3 42.1 18.1 32.7 21.5 1.3 66.9 20.0 29.6 76.8 43.0 51.0 30.5 12.8 15.9 63.8 24.2 133.6 301.5 18.1 18.6 25.5 1676.3 70.8 27.4 19.3 19.0 165.1 14.0 6.4 16.0 26.1 19.9 23.0 80.2 4.3 126.7 24.0 21.1 74.5 52.1 32.5 19.5 13.9 46.9 14.3 21.6 12.1 102.5 84.0 25.9 149.9 27.0 21.1 0.0 64.9 0.0 0.0 96.5 54.7 0.1 25.8 63.1 3.5 13.5 0.1 11.9 0.3 9.6 0.1 0.2 2.2 0.0 23.6 2.6 1.3 0.0 20.0 74.7 0.0 123.1 0.9 0.3 119.5 0.3 18.4 7.9 374.9 79.2 0.0 74.4 2.7 89.4 0.1 0.5 0.1 0.4 0.0 0.1 0.2 89.8 21.0 0.0 227.0 0.0 0.1 0.4 0.0 0.1 0.6 0.1 0.0 5.6 73.6 0.9 0.8 0.8 0.8 0.0 0.3 13.1 0.2 5.8 0.0 0.1 0.0 2.0 0.0 18.7 0.0 6.6 4.0 0.2 0.0 0.4 1.5 0.7 0.0 0.0 0.0 0.0 1.1 18.1 21.5 20.0 29.6 18.1 18.6 19.3 19.0 19.9 19.5 21.6 21.1 73.9 9.6 17.6 0.7 4.2 44.2 63.6 140.6 14.2 2.4 1.3 3.4 10.9 35.8 141.1 5.5 0.0 0.0 3.1 0.1 0.0 6.2 2.6 2.3 3.8 49.8 0.0 52.6 0.6 0.8 0.0 448.0 8.6 1.9 3.8 6.9 47.8 1114.8 1.1 0.0 1.0 0.0 14.2 43.8 62.1 7.4 283.9 5.7 44.4 38.4 0.3 0.3 0.0 0.0 0.2 5.3 0.0 138.8 2.6 13.0 0.0 0.5 115.6 1.4 6.6 94.2 59.6 1.4 1.0 10.9 38.2 0.1 13.2 26.3 0.0 61.5 CFHR1 "CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2" ENSG00000244414 "Complement factor H related 1" Q03591 1 196819731-196832189 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 272 "liver: 2081.3" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 320.0" "Cancer enriched" "Detected in single" 798 "liver cancer: 182.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.0;HeLa: 1.2;HL-60: 2.0;U-266/70: 2.4" "Not detected" "Not detected" "HPA038915, HPA038922, HPA040726" Supported Approved Vesicles "Secreted to blood" NA NA 13000000000 "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA038915: AB_2676269, HPA038922: AB_2676271, HPA040726: AB_2677101" "unprognostic (2.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.50e-2)" "unprognostic (1.88e-2)" "prognostic favorable (8.71e-6)" "unprognostic (3.02e-1)" "unprognostic (3.70e-1)" "unprognostic (2.50e-1)" "unprognostic (8.48e-2)" "unprognostic (7.21e-4)" "unprognostic (7.01e-4)" "unprognostic (1.13e-1)" "unprognostic (6.41e-2)" 1.5 0.6 0.1 1.8 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.2 7.6 2081.3 0.1 6.7 0.1 0.8 0.3 0.3 0.0 0.1 0.1 0.4 0.2 0.2 0.2 0.1 0.0 0.2 0.1 0.7 0.2 0.1 6.1 0.2 0.1 0.2 0.0 0.1 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.9 0.3 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.1 0.1 0.0 2.4 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.8 0.4 0.1 0.2 0.1 0.5 3.2 0.0 0.0 2.2 0.4 0.1 0.0 0.0 1.2 0.0 0.1 1.8 11.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 18.7 0.0 0.0 0.0 9.9 0.0 0.0 0.0 6.0 15.0 320.0 5.6 0.0 0.4 0.0 0.0 16.9 0.4 0.2 1.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 41.0 2.1 0.3 1.5 0.0 0.0 0.3 1.4 5.6 0.1 0.1 CFHR3 "CFHL3, DOWN16, FHR-3, FHR3, HLF4" ENSG00000116785 "Complement factor H related 3" Q02985 1 196774813-196795407 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 582 "liver: 505.7" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 205.5" "Cancer enriched" "Detected in single" 80 "liver cancer: 27.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.7;SuSa: 1.5;T-47d: 3.6;U-266/70: 6.4" "Secreted to blood" NA NA 582000000 3100000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (1.73e-1)" "unprognostic (2.11e-1)" "unprognostic (7.16e-2)" "unprognostic (6.77e-2)" "unprognostic (4.46e-1)" "unprognostic (4.20e-3)" "prognostic favorable (2.86e-5)" "unprognostic (1.78e-1)" "unprognostic (2.05e-2)" "unprognostic (1.98e-1)" "unprognostic (1.19e-2)" "unprognostic (6.11e-3)" "unprognostic (2.06e-10)" "unprognostic (2.67e-4)" "unprognostic (3.00e-1)" "unprognostic (3.29e-2)" "unprognostic (1.32e-1)" 0.8 0.2 0.1 0.2 0.2 0.1 0.2 0.0 0.4 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.4 505.7 0.2 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.1 0.1 0.3 0.0 0.3 0.1 0.0 0.4 0.1 0.6 0.0 0.7 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.6 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.4 0.0 0.9 0.0 0.0 0.0 0.3 0.0 1.5 3.6 0.0 0.0 0.1 0.2 0.3 0.0 6.4 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.5 1.8 16.0 0.1 0.0 0.1 1.7 0.0 0.0 0.0 0.0 7.1 205.5 0.0 0.0 0.1 0.0 0.0 8.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.7 CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109801999 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1098.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 108.7;Hepatocytes: 592.5;Muller glia cells: 147.8;Proximal tubular cells: 223.6" "Cancer enhanced" "Detected in all" "liver cancer: 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 106.1;Hep G2: 179.8;HSkMC: 67.4;RPTEC TERT1: 190.6" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" NA NA 12000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" 45.1 50.2 8.1 12.6 8.2 0.1 17.4 7.7 13.2 36.8 10.4 7.4 38.0 39.2 80.3 9.3 74.0 73.0 25.0 8.3 9.6 224.9 1098.8 50.7 8.9 15.6 10.2 32.1 26.0 3.1 8.4 24.1 10.7 8.3 6.4 53.0 15.0 26.7 3.9 2.7 22.3 24.3 10.5 33.1 14.4 8.8 9.2 2.3 14.5 4.6 7.5 34.1 8.3 10.6 0.0 0.6 0.0 0.3 0.0 0.2 0.1 1.5 1.4 0.1 0.2 0.0 106.1 0.0 32.9 0.0 0.5 0.0 0.0 0.0 0.0 34.8 0.7 0.0 0.4 179.8 6.2 0.3 0.0 67.4 0.0 0.1 0.0 3.6 4.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 190.6 0.5 0.0 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.0 0.1 18.8 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 8.2 7.7 13.2 8.3 9.6 15.6 10.2 10.7 10.5 9.2 10.6 48.1 12.8 50.9 3.6 4.0 1.0 12.2 15.2 0.6 3.4 2.1 5.6 2.3 108.7 36.2 64.4 2.1 0.1 0.3 1.7 31.3 69.3 0.2 34.1 46.4 57.7 0.0 2.7 0.3 30.9 0.2 34.3 8.2 33.6 3.8 72.1 55.0 592.5 0.7 1.7 0.2 1.9 0.0 16.7 1.5 0.8 16.8 2.0 0.0 4.7 1.6 147.8 0.0 0.0 0.3 30.8 2.4 0.0 0.0 3.8 17.0 223.6 8.4 7.3 0.0 1.3 9.4 1.6 0.5 1.9 1.1 0.3 3.4 18.5 4.1 12.6 COX4I2 "COX4-2, COX4B, COX4L2, COXIV-2, dJ857M17.2" ENSG00000131055 "Cytochrome c oxidase subunit 4I2" Q96KJ9 20 31637912-31645006 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 49.1;placenta: 115.4" "Group enriched" "Detected in some" 5 "Sertoli cells: 414.2;Smooth muscle cells: 191.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "SH-SY5Y: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (2.64e-1)" "unprognostic (2.09e-2)" "unprognostic (2.76e-3)" "unprognostic (2.18e-2)" "unprognostic (4.51e-2)" "prognostic favorable (6.04e-5)" "unprognostic (5.60e-2)" "unprognostic (1.13e-1)" "unprognostic (2.51e-1)" "unprognostic (7.45e-2)" "unprognostic (1.04e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (9.78e-4)" "unprognostic (1.11e-1)" "unprognostic (3.30e-3)" "unprognostic (1.43e-1)" "unprognostic (5.59e-2)" 19.1 1.1 6.7 1.7 6.7 0.0 15.9 6.5 9.1 4.8 6.1 4.7 1.9 7.5 3.9 5.4 4.9 10.6 39.7 6.5 6.7 10.9 1.1 49.1 4.7 6.8 7.0 2.9 2.3 9.3 2.2 115.4 7.0 10.1 2.7 1.1 3.6 4.7 8.7 4.9 5.8 7.1 6.6 1.7 4.2 1.5 7.0 1.8 14.7 19.4 3.0 7.7 6.7 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 6.7 6.5 9.1 6.5 6.7 6.8 7.0 7.0 6.6 7.0 6.6 55.0 0.0 0.0 0.0 0.5 6.4 0.3 0.0 2.2 0.4 0.9 1.9 2.7 0.0 0.0 0.0 0.0 1.1 0.3 0.1 0.0 0.0 0.2 0.1 0.7 23.5 0.0 0.0 0.0 0.0 0.3 9.5 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 7.5 0.7 3.7 0.5 8.8 2.8 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.7 414.2 4.6 191.6 0.1 1.0 0.8 6.7 2.5 1.0 1.0 0.0 0.3 CUBN "gp280, IFCR, MGA1" ENSG00000107611 Cubilin O60494 10 16823966-17129811 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Protein transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 140.4" "Group enriched" "Detected in many" 7 "Proximal enterocytes: 257.7;Proximal tubular cells: 325.0" "Cancer enriched" "Detected in some" 15 "renal cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 14.8;ASC TERT1: 3.0;SK-MEL-30: 2.8;WM-115: 5.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004133, HPA043854" Enhanced "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA004133: AB_2732398, HPA043854: AB_2732510" "unprognostic (1.75e-1)" "unprognostic (2.35e-1)" "unprognostic (2.12e-3)" "unprognostic (8.61e-4)" "unprognostic (9.54e-2)" "unprognostic (2.78e-2)" "unprognostic (2.88e-2)" "unprognostic (7.03e-2)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.47e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.24e-3)" "unprognostic (1.97e-1)" "unprognostic (2.00e-1)" "unprognostic (1.93e-1)" 0.7 0.8 0.8 0.4 0.9 0.4 0.8 0.8 0.7 1.2 1.3 0.5 0.2 0.7 3.1 0.2 2.1 0.3 0.6 0.8 0.8 140.4 0.1 0.6 0.8 2.5 1.7 2.5 0.5 0.6 2.2 2.6 2.4 1.1 0.2 3.0 0.7 0.4 0.3 0.8 28.0 0.4 1.7 0.9 0.4 2.0 1.0 1.7 3.8 0.5 0.7 0.4 0.7 0.6 0.0 0.0 1.5 14.8 0.5 3.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.8 1.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.6 1.5 0.6 0.1 0.2 0.2 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.3 0.0 0.0 2.8 0.1 0.0 0.1 1.6 0.1 0.2 0.3 0.1 0.5 0.0 0.0 0.4 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.9 0.8 0.7 0.8 0.8 2.5 1.7 2.4 1.7 1.0 0.6 3.2 0.0 1.5 23.8 3.7 0.5 0.4 0.2 0.6 2.9 0.6 0.6 1.7 0.0 3.2 5.5 2.1 0.0 3.3 0.1 13.7 0.0 37.3 3.1 2.2 5.7 0.0 0.0 8.4 0.2 0.0 2.3 0.0 2.2 0.0 2.2 1.4 0.0 0.1 0.0 9.0 3.7 0.0 0.3 0.4 31.8 2.8 3.1 7.2 7.5 0.1 6.5 1.0 9.0 5.5 0.1 5.0 1.2 1.6 0.4 257.7 325.0 3.5 4.0 0.0 19.0 1.6 1.1 0.9 0.1 0.9 0.1 2.9 1.2 1.2 0.2 CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 889.6;liver: 2472.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 1371.0;Distal tubular cells: 2156.1;Hepatocytes: 3376.3;Proximal enterocytes: 1856.4;Proximal tubular cells: 3630.6" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1117.0;RT4: 513.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" 309.5 109.6 38.4 31.2 39.7 25.3 253.5 42.2 45.2 86.0 37.6 146.5 438.2 44.9 176.2 78.1 81.9 301.2 84.8 37.5 38.8 889.6 2472.0 356.6 43.7 43.1 39.7 223.9 461.3 236.0 58.5 81.8 41.9 95.9 103.4 10.3 59.1 122.8 41.4 118.4 381.7 46.7 40.8 75.6 194.8 57.9 40.0 51.6 42.5 42.1 35.2 155.5 68.3 43.5 78.8 130.8 67.4 0.6 1117.0 198.2 89.5 52.6 113.8 111.0 163.8 156.2 82.7 95.6 36.7 97.6 54.4 170.6 0.1 73.1 86.9 179.8 91.7 34.9 65.6 418.1 174.6 67.3 44.1 334.1 57.4 63.0 32.3 66.0 63.6 85.8 58.6 35.0 93.7 140.9 38.3 80.5 30.4 110.0 86.8 93.6 21.9 2.3 111.9 513.2 190.4 79.7 51.4 137.1 65.8 56.6 271.5 63.7 57.9 0.6 85.8 26.6 68.1 24.6 109.2 30.3 67.0 19.2 64.3 4.1 29.5 7.5 51.3 36.3 116.2 93.7 55.6 60.2 53.7 112.7 54.5 68.6 3.7 36.3 45.7 47.8 48.8 43.2 38.4 39.7 42.2 45.2 37.5 38.8 43.1 39.7 41.9 40.8 40.0 43.5 169.7 637.8 1371.0 11.4 76.0 98.0 82.1 368.6 50.7 9.9 345.8 213.2 90.7 836.4 1053.2 842.4 4.2 229.3 29.4 197.0 2156.1 239.4 7.5 163.1 76.6 119.9 164.2 180.0 13.1 504.6 169.8 141.4 208.9 345.6 39.9 55.0 177.4 3376.3 97.4 8.4 12.6 236.5 457.7 128.6 72.9 26.7 158.1 60.8 90.7 10.3 224.1 39.2 32.0 14.1 22.7 266.7 358.9 149.7 33.4 142.0 1856.4 3630.6 619.5 14.0 52.6 49.6 85.0 15.3 42.0 141.2 223.9 44.5 52.6 1123.6 329.9 220.7 CYB5R3 DIA1 ENSG00000100243 "Cytochrome b5 reductase 3" P00387 22 42617840-42649392 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 830.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001566 Approved Supported "Endoplasmic reticulum" NA NA 1500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "HPA001566: AB_1078601" "unprognostic (4.73e-2)" "unprognostic (2.93e-1)" "unprognostic (1.79e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.45e-1)" "unprognostic (8.22e-3)" "unprognostic (3.01e-1)" "unprognostic (2.72e-2)" "unprognostic (6.76e-2)" "unprognostic (3.33e-3)" "unprognostic (1.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-1)" "unprognostic (5.24e-2)" 404.4 310.5 147.1 87.4 152.9 82.7 272.2 145.7 189.9 237.3 115.0 192.4 94.8 248.4 58.8 152.4 174.0 139.5 374.3 138.7 163.9 182.9 279.4 201.3 76.3 194.7 174.2 218.3 89.1 62.0 137.4 107.8 169.9 181.4 74.9 27.3 149.8 239.3 203.0 233.6 138.1 200.2 154.8 101.4 182.0 142.7 156.7 54.0 157.8 140.5 72.3 216.7 210.0 160.2 125.5 78.6 126.6 78.6 830.9 654.7 74.4 359.2 330.0 262.2 232.4 104.0 95.6 58.8 156.6 668.8 113.8 112.4 85.3 178.0 133.7 63.9 187.3 83.6 127.3 202.4 211.0 118.4 149.5 397.4 138.1 188.9 124.5 190.8 220.0 74.0 73.5 296.3 361.9 137.9 116.8 108.4 51.0 129.2 142.7 84.9 153.8 131.3 202.0 90.6 56.1 73.2 118.6 113.2 134.0 92.6 90.6 112.0 340.9 282.0 175.3 192.3 137.9 78.3 91.2 72.4 328.8 67.8 237.9 126.3 104.0 300.3 75.9 135.3 76.6 110.1 72.8 83.9 154.0 102.7 50.8 54.0 53.8 63.5 176.7 140.8 95.0 86.4 147.1 152.9 145.7 189.9 138.7 163.9 194.7 174.2 169.9 154.8 156.7 160.2 238.5 86.6 62.2 17.0 51.7 110.1 95.5 184.8 27.3 16.7 52.3 73.2 106.4 105.8 100.9 60.7 4.2 110.0 37.0 90.5 49.0 216.4 4.8 51.4 82.9 161.5 83.7 113.9 12.3 107.0 199.3 183.4 38.2 65.4 62.8 57.8 180.2 230.4 108.3 16.8 16.1 45.8 142.4 50.6 112.0 17.0 253.9 67.7 176.1 25.3 112.5 91.0 33.0 7.1 26.4 156.8 85.6 280.6 36.7 82.3 116.9 110.8 53.3 18.4 190.7 62.5 202.5 23.8 45.5 57.5 112.7 117.9 43.0 233.1 55.2 96.4 CYCS "CYC, HCS" ENSG00000172115 "Cytochrome c, somatic" P99999 7 25118656-25125260 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Electron transport, Respiratory chain, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 799.8" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1663.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004222, CAB005126, CAB018597" Enhanced Supported Mitochondria NA NA 170000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "CAB004222: AB_627385, CAB005126: AB_2090472, CAB018597: AB_627383" "unprognostic (3.06e-2)" "unprognostic (3.39e-1)" "unprognostic (3.32e-2)" "unprognostic (4.11e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.81e-4)" "unprognostic (4.44e-2)" "unprognostic (7.04e-3)" "unprognostic (5.67e-2)" "unprognostic (6.22e-2)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.30e-5)" "unprognostic (1.18e-1)" "unprognostic (4.94e-2)" "unprognostic (8.75e-3)" "unprognostic (7.04e-2)" 86.0 115.6 65.8 89.2 70.4 85.0 59.2 79.8 101.7 45.3 87.6 263.6 150.1 42.3 41.5 105.9 43.0 52.9 476.8 72.1 82.8 174.6 115.7 54.3 63.8 71.0 72.9 48.1 38.5 226.2 57.0 43.0 69.4 54.3 238.8 153.9 58.0 60.1 483.7 47.6 120.1 91.1 70.2 48.0 108.1 61.1 83.4 74.0 74.6 799.8 89.4 119.8 60.1 71.7 336.4 185.1 195.0 273.7 108.7 83.1 199.6 314.4 128.0 229.2 264.5 307.4 222.2 383.8 152.9 138.5 678.3 385.8 396.5 295.0 401.2 115.0 179.1 318.6 208.9 218.7 170.2 739.0 271.1 111.2 257.5 230.9 492.9 99.4 209.5 232.2 597.1 397.9 246.0 155.1 408.6 284.4 365.1 746.3 343.0 282.1 235.3 364.5 360.9 322.5 392.6 190.3 164.5 689.0 267.9 338.7 359.5 436.6 152.8 209.3 383.3 329.8 591.8 401.4 507.3 860.5 281.0 526.4 606.7 65.3 56.2 42.8 68.0 106.0 82.5 102.5 62.2 71.6 105.7 90.0 58.6 70.2 8.2 73.3 96.8 81.5 87.5 83.0 65.8 70.4 79.8 101.7 72.1 82.8 71.0 72.9 69.4 70.2 83.4 71.7 244.3 83.3 118.6 42.4 337.6 689.8 818.3 698.5 237.9 163.1 210.6 179.6 770.0 144.4 314.2 183.9 77.2 192.6 304.4 827.5 1663.0 278.3 496.4 154.8 120.2 183.3 384.9 162.6 53.2 216.0 351.0 257.3 287.5 197.5 212.6 68.7 81.0 210.8 353.0 132.9 64.6 522.5 502.5 141.5 715.2 161.8 90.1 329.2 590.5 16.9 245.8 220.9 197.8 17.1 24.2 303.8 570.5 93.6 358.7 551.9 392.8 638.6 146.1 195.2 138.1 294.7 962.3 423.1 211.1 402.7 715.2 349.3 349.7 146.9 600.2 884.1 DIAPH1 "DFNA1, hDIA1, LFHL1" ENSG00000131504 "Diaphanous related formin 1" O60610 5 141515016-141619055 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hearing Actin-binding "Cancer-related genes, Deafness, Disease variant, Epilepsy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 172.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 564.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004916, HPA076913" Approved Uncertain "Plasma membrane,Cytosol" NA NA 2000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA004916: AB_1847668, HPA076913: " "unprognostic (6.79e-2)" "unprognostic (2.99e-1)" "unprognostic (2.12e-3)" "unprognostic (3.73e-2)" "unprognostic (4.18e-2)" "unprognostic (1.54e-1)" "unprognostic (2.08e-1)" "unprognostic (4.54e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "prognostic unfavorable (7.81e-5)" "unprognostic (2.88e-3)" "prognostic favorable (1.29e-5)" "unprognostic (1.64e-2)" "unprognostic (1.84e-2)" "unprognostic (7.00e-2)" "unprognostic (1.65e-1)" 27.9 20.3 21.0 42.1 22.5 90.2 24.2 18.3 20.9 24.4 40.0 31.0 40.6 18.5 44.3 58.0 25.2 30.0 34.9 21.5 25.7 38.1 91.7 51.3 67.0 18.8 19.9 12.9 37.3 44.6 24.5 25.1 20.1 14.7 31.1 28.4 36.1 19.3 172.0 47.3 36.5 18.7 18.0 36.3 45.1 19.9 27.4 68.5 33.1 55.7 66.4 47.1 30.4 18.6 147.8 92.6 53.2 68.4 40.4 54.5 71.3 59.5 62.2 67.7 70.2 318.1 131.6 156.5 88.1 85.5 103.0 157.9 116.9 191.5 84.8 88.9 66.6 282.6 121.4 103.6 37.7 198.9 564.7 34.4 102.1 94.5 95.5 30.5 87.0 234.8 101.2 106.9 67.7 141.5 217.2 256.8 51.6 75.2 61.6 240.1 87.1 87.6 129.8 158.5 69.4 37.3 146.2 184.6 59.5 47.5 77.5 92.1 52.8 93.9 49.9 52.1 119.9 54.2 94.4 111.7 50.2 153.7 57.8 23.6 12.8 29.8 32.6 14.0 21.2 9.3 20.3 25.3 12.6 9.1 14.8 23.9 13.7 13.7 15.1 10.0 18.7 15.4 21.0 22.5 18.3 20.9 21.5 25.7 18.8 19.9 20.1 18.0 27.4 18.6 33.9 48.1 46.8 11.8 40.0 52.6 60.8 22.4 21.6 17.3 35.1 23.1 18.6 22.8 48.0 44.1 54.2 20.9 96.9 60.5 5.9 62.7 27.9 42.3 18.9 39.0 5.4 52.6 44.1 98.0 31.9 25.9 76.0 83.0 46.9 14.5 16.8 91.6 17.1 6.7 33.6 23.1 12.2 38.4 60.6 9.0 11.8 78.5 19.6 24.4 54.6 12.1 115.4 25.6 9.1 122.9 35.7 10.9 54.1 77.3 35.2 13.9 30.4 69.0 13.1 15.4 26.4 18.3 26.1 38.7 59.7 52.1 92.8 18.3 30.1 91.2 DNMT3A ENSG00000119772 "DNA methyltransferase 3 alpha" Q9Y6K1 2 25227855-25342590 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 127.2;Horizontal cells: 95.9;Rod photoreceptor cells: 143.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 59.6;REH: 59.5;SH-SY5Y: 71.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009469, HPA026588" Approved Supported Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB009469: AB_2093990, HPA026588: AB_1847812" "unprognostic (2.38e-1)" "unprognostic (2.94e-1)" "unprognostic (5.65e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (8.38e-2)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-1)" "prognostic favorable (1.18e-4)" "unprognostic (2.35e-2)" "prognostic unfavorable (2.49e-4)" "unprognostic (1.43e-1)" "unprognostic (1.87e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-2)" 5.6 9.0 8.9 9.8 12.6 8.7 6.2 9.3 10.7 9.1 2.4 11.3 6.7 9.3 8.7 6.0 7.5 6.3 5.9 8.8 7.9 11.3 5.3 7.3 11.1 9.0 7.6 13.0 8.3 4.2 11.5 15.7 8.6 7.2 6.6 15.4 6.2 5.9 21.0 4.9 8.9 7.1 5.2 13.4 8.5 5.2 9.4 20.6 6.9 10.2 9.0 7.3 6.2 11.3 1.6 8.1 34.6 8.3 3.8 2.7 45.2 1.9 2.2 4.7 3.8 21.1 13.2 0.0 4.7 4.7 3.5 2.2 3.8 5.2 2.8 5.7 4.3 14.7 12.8 25.4 8.8 2.9 7.6 8.2 2.6 6.0 2.2 9.1 19.5 34.0 18.0 2.9 3.5 20.6 33.7 36.5 59.6 14.3 4.2 59.5 32.5 3.8 2.9 3.4 18.6 71.5 2.7 19.6 6.2 29.5 2.1 16.2 6.8 5.4 4.7 1.0 2.5 5.6 5.1 19.6 2.2 8.4 5.5 2.8 1.0 2.1 2.7 1.7 4.0 1.3 1.7 2.4 1.3 1.6 4.6 3.9 2.5 5.5 2.7 2.3 1.9 1.2 8.9 12.6 9.3 10.7 8.8 7.9 9.0 7.6 8.6 5.2 9.4 11.3 18.5 6.4 13.1 28.1 11.0 5.2 10.2 6.6 5.7 73.3 12.1 9.8 15.8 5.7 9.9 20.2 127.2 40.6 15.3 6.3 5.9 16.9 1.6 13.3 19.1 20.5 13.1 15.8 49.4 9.8 10.7 16.4 9.7 10.7 37.4 37.3 11.0 6.4 23.2 95.9 43.2 11.4 2.0 14.2 3.9 1.9 19.3 13.7 7.2 38.4 7.4 20.6 13.4 36.7 63.4 9.3 9.4 15.4 9.8 12.4 6.2 6.6 7.3 143.5 19.7 15.1 14.3 2.8 14.6 8.1 2.6 32.2 19.6 26.1 12.1 10.2 EGLN1 "C1orf12, HIFPH2, PHD2, SM-20, ZMYND6" ENSG00000135766 "Egl-9 family hypoxia inducible factor 1" Q9GZT9 1 231363751-231422287 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 190.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 29.1" "Lineage enriched" "Detected in many" 15 "granulocytes: 29.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022129 Approved NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA022129: AB_1848046" "unprognostic (4.20e-1)" "prognostic unfavorable (2.99e-7)" "unprognostic (8.86e-2)" "unprognostic (1.26e-1)" "unprognostic (3.87e-1)" "unprognostic (1.67e-1)" "unprognostic (1.20e-1)" "unprognostic (3.87e-3)" "unprognostic (1.91e-1)" "unprognostic (3.99e-1)" "unprognostic (6.63e-2)" "unprognostic (9.71e-2)" "unprognostic (3.82e-2)" "unprognostic (1.23e-1)" "unprognostic (1.55e-1)" "unprognostic (5.65e-2)" "unprognostic (1.81e-2)" 32.8 35.6 37.5 18.1 40.8 20.0 23.9 38.8 43.2 26.3 31.6 30.0 34.0 30.8 24.5 33.6 24.2 28.2 58.7 39.9 37.2 38.8 56.5 19.1 21.1 41.6 39.0 37.5 40.0 39.0 9.3 42.6 36.8 23.8 26.1 49.9 22.0 30.3 190.7 48.6 35.5 27.6 40.9 27.6 19.1 17.1 43.4 16.7 25.5 153.4 21.3 27.0 12.0 40.9 54.2 59.9 17.5 33.7 44.8 29.4 15.8 22.7 42.2 36.3 49.4 41.3 48.0 15.5 41.7 42.4 31.7 25.1 26.8 30.1 61.0 18.6 42.5 6.7 23.5 37.7 31.5 38.5 8.1 25.4 27.5 24.9 34.2 58.6 49.3 18.5 33.9 37.9 38.3 12.2 8.9 14.4 18.4 33.4 21.0 20.0 21.7 22.7 48.0 23.4 15.9 45.3 32.9 41.4 83.1 11.2 22.4 112.8 54.3 44.3 20.8 40.5 47.2 65.7 46.4 14.7 60.4 14.0 59.4 4.2 0.5 3.1 1.2 1.0 0.7 0.7 0.9 0.8 0.8 0.7 1.0 1.8 29.1 1.6 1.8 0.7 0.5 0.4 37.5 40.8 38.8 43.2 39.9 37.2 41.6 39.0 36.8 40.9 43.4 40.9 64.7 19.2 23.2 36.6 19.8 58.5 15.0 10.7 33.0 32.3 19.4 13.3 111.9 67.2 11.6 18.4 37.5 16.2 16.6 57.6 35.2 37.8 1.2 18.5 20.2 60.6 12.7 8.2 43.9 36.2 34.2 25.9 15.3 21.2 10.1 55.6 28.9 70.6 16.9 62.2 52.6 24.6 16.2 24.1 45.3 5.0 16.1 29.8 26.6 44.0 19.0 56.9 12.3 46.3 48.3 36.6 30.9 23.0 23.9 15.1 43.2 52.3 13.5 44.0 19.7 36.4 36.6 13.1 20.9 24.9 57.5 10.4 24.9 16.0 23.5 21.3 EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 412.0;placenta: 445.6" "Cell type enhanced" "Detected in many" "Adipocytes: 831.5;Endothelial cells: 425.8;Hepatic stellate cells: 538.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.6;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.6" "Cell line enhanced" "Detected in many" "BEWO: 267.3;BJ hTERT+: 266.7;HHSteC: 326.3;RT4: 339.8;TIME: 337.8;U-138 MG: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA031200: AB_2673785, HPA069697: AB_2732139" "unprognostic (1.74e-1)" "unprognostic (9.47e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (8.67e-2)" "unprognostic (6.00e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.29e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.66e-3)" "unprognostic (7.75e-2)" "unprognostic (7.56e-2)" "unprognostic (1.36e-1)" 296.0 52.1 53.4 66.1 48.6 2.3 166.7 44.6 47.7 72.9 139.1 57.1 46.3 87.9 26.0 72.7 80.1 83.2 122.1 39.2 44.7 89.5 110.1 412.0 47.9 60.5 54.2 34.5 59.6 79.4 25.9 445.6 60.2 51.8 42.6 53.6 40.0 66.3 80.5 42.9 50.9 71.7 45.6 84.6 42.8 20.0 75.4 17.9 138.1 153.6 40.3 94.9 47.8 44.6 32.2 33.5 2.1 2.5 153.8 98.6 267.3 98.7 266.7 55.6 60.1 5.8 5.5 0.1 23.8 188.5 55.2 15.2 0.6 79.0 41.3 0.9 1.6 0.0 10.3 71.8 326.3 0.1 19.8 145.0 106.9 108.7 75.8 41.0 193.1 0.7 3.1 0.2 34.2 27.8 0.9 0.8 1.3 22.4 18.5 1.0 3.7 10.5 34.5 339.8 1.4 68.5 77.4 175.5 21.0 68.3 11.7 14.1 337.8 284.0 8.1 38.3 8.4 0.2 0.2 0.1 207.4 5.4 7.4 20.6 0.1 8.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.1 53.4 48.6 44.6 47.7 39.2 44.7 60.5 54.2 60.2 45.6 75.4 44.6 831.5 76.9 151.7 28.4 4.1 48.2 69.8 108.6 43.9 4.5 27.4 29.5 79.2 32.9 124.9 3.7 10.4 126.2 6.6 112.6 1.9 23.0 12.9 36.1 32.7 425.8 4.2 18.7 1.2 52.4 299.9 76.8 32.1 67.6 41.2 2.3 538.7 78.0 55.5 0.0 1.6 13.9 22.4 60.9 30.3 52.7 12.5 21.4 28.4 155.5 0.6 95.5 0.0 31.2 1.3 26.1 53.7 6.4 3.9 57.8 45.9 30.2 31.7 59.3 282.7 23.3 250.5 1.5 4.6 65.0 33.2 349.7 15.9 4.7 23.6 85.7 EPB41 "4.1R, EL1" ENSG00000159023 "Erythrocyte membrane protein band 4.1" P11171 1 28887091-29120046 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Cell division, Mitosis, Transport" "Actin-binding, Calmodulin-binding" "Elliptocytosis, Hereditary hemolytic anemia, Pyropoikilocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 80.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 151.6;Cone photoreceptor cells: 137.6;Erythroid cells: 187.1;Rod photoreceptor cells: 171.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 42.2" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 136.3;K-562: 136.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "cerebellum: 105.6" "HPA028076, HPA028096, HPA028412, HPA028414" Supported Supported "Nuclear bodies,Plasma membrane,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No 1100000 "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cell Junctions" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA028076: AB_2672476, HPA028096: , HPA028412: AB_2672592, HPA028414: AB_10601366" "unprognostic (2.16e-1)" "unprognostic (1.96e-1)" "unprognostic (8.92e-3)" "prognostic unfavorable (4.58e-4)" "unprognostic (5.00e-2)" "prognostic favorable (5.87e-4)" "unprognostic (5.01e-3)" "unprognostic (5.40e-3)" "unprognostic (2.52e-2)" "unprognostic (6.65e-2)" "unprognostic (7.81e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (2.66e-2)" "unprognostic (2.42e-1)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" 11.0 10.2 1.8 21.9 18.3 63.3 14.1 42.2 6.0 14.5 4.9 23.6 17.7 10.2 5.3 16.6 6.3 15.0 9.7 1.2 4.7 12.7 21.7 15.1 37.4 8.2 5.6 16.3 18.8 15.5 4.7 7.2 8.5 15.0 23.1 80.0 19.1 9.1 15.9 15.3 23.3 9.9 3.5 22.9 27.0 10.4 4.7 69.0 15.2 13.8 37.0 15.5 1.9 3.0 27.0 6.9 62.3 29.4 5.2 0.8 19.5 6.9 10.1 8.4 10.5 16.8 31.2 49.1 17.2 9.2 13.5 11.9 78.7 6.6 8.6 86.4 23.8 136.3 19.7 28.6 10.1 45.8 88.2 1.7 18.4 8.2 13.8 19.9 14.1 73.5 136.5 36.2 0.1 8.8 72.3 30.4 62.0 44.1 10.0 110.9 28.2 68.3 7.7 33.3 78.0 60.5 19.7 19.2 43.3 21.7 14.7 18.2 1.2 0.3 13.3 12.9 13.4 52.5 72.4 85.2 12.1 47.8 6.8 33.3 3.2 21.4 12.9 1.1 15.4 17.2 18.3 14.1 4.4 13.6 22.1 12.7 44.2 10.9 1.5 4.4 28.9 15.3 1.8 18.3 42.2 6.0 1.2 4.7 8.2 5.6 8.5 3.5 4.7 3.0 25.3 19.2 71.7 20.2 58.2 10.5 8.6 7.8 15.4 151.6 20.0 12.2 21.5 20.0 16.8 16.5 137.6 2.4 75.3 26.5 17.6 17.1 16.4 11.3 4.1 15.1 41.6 187.1 76.3 18.7 4.2 7.9 29.6 29.1 24.1 24.9 17.5 30.0 7.1 21.9 61.7 29.0 16.2 23.7 9.0 22.7 2.1 32.4 0.0 78.7 29.3 15.7 85.5 7.5 4.8 28.6 20.3 2.2 46.7 12.2 32.8 13.4 15.2 171.4 13.1 2.8 8.5 39.3 55.7 14.9 16.8 4.1 71.6 4.2 33.0 12.6 EPB42 "MGC116735, MGC116737, PA" ENSG00000166947 "Erythrocyte membrane protein band 4.2" P16452 15 43197227-43221018 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape, Erythrocyte maturation" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "bone marrow: 98.9" "Cell type enriched" "Detected in many" 33 "Erythroid cells: 480.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 91 "HEL: 85.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040261 Supported Uncertain Nucleoplasm,Cytosol NA NA 1400000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Cytosol" "HPA040261: AB_10673441" "unprognostic (8.45e-2)" "unprognostic (4.66e-1)" "unprognostic (4.15e-1)" "unprognostic (1.13e-1)" "unprognostic (2.28e-1)" "unprognostic (1.99e-1)" "unprognostic (1.54e-1)" "unprognostic (1.59e-3)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" "unprognostic (5.27e-3)" "unprognostic (1.31e-1)" "unprognostic (1.48e-5)" "unprognostic (1.70e-2)" "unprognostic (1.20e-1)" "unprognostic (5.88e-2)" "unprognostic (3.47e-3)" 3.1 0.0 0.0 0.0 0.0 98.9 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 2.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 1.9 1.5 0.5 0.0 4.0 0.0 0.0 0.6 1.5 0.5 0.0 6.2 4.5 0.0 1.5 0.0 0.0 14.4 0.0 0.0 1.2 0.0 480.0 0.1 0.0 2.3 0.8 0.0 0.0 4.5 0.0 2.5 1.1 1.1 6.7 0.1 0.9 4.1 2.2 2.8 10.5 2.8 1.1 1.8 0.0 3.6 2.5 14.4 0.0 0.0 0.0 1.7 0.7 0.4 1.5 2.4 0.0 0.6 8.4 6.6 1.0 1.0 13.5 4.6 0.0 2.8 6.7 3.8 0.0 0.8 2.0 EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 114.7;Hepatic stellate cells: 66.8;Hofbauer cells: 42.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.70e-1)" "unprognostic (1.50e-2)" "unprognostic (5.60e-2)" "unprognostic (9.00e-2)" "prognostic favorable (3.17e-5)" "unprognostic (6.37e-3)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-1)" "unprognostic (7.48e-2)" "unprognostic (1.01e-3)" 6.5 17.5 6.0 1.4 6.3 22.4 5.0 6.7 8.2 7.1 7.7 2.7 1.4 3.3 13.6 1.3 6.7 2.3 9.7 6.3 6.0 21.6 10.7 6.4 2.2 6.1 6.1 3.1 11.8 23.2 8.2 8.0 6.4 4.6 1.7 3.3 3.3 7.3 2.3 1.6 2.3 1.8 6.0 11.9 7.8 1.8 6.2 1.7 30.2 1.5 1.6 3.1 3.7 6.3 3.7 1.2 3.6 4.2 5.3 3.4 2.1 2.2 7.0 3.6 4.5 1.3 1.4 2.5 4.0 4.1 5.0 0.9 2.8 1.4 4.1 2.1 1.6 14.3 1.3 2.1 3.8 2.9 5.5 2.4 0.5 4.8 3.3 8.5 8.5 5.3 12.5 12.0 4.1 3.3 2.7 3.5 1.9 2.0 9.6 7.2 6.3 5.6 3.4 1.9 1.4 11.0 1.5 2.0 6.4 3.7 3.6 4.9 3.5 1.9 2.6 6.6 2.1 6.0 4.7 2.8 10.5 2.9 2.1 9.3 3.7 3.0 1.7 4.6 3.6 2.0 3.4 2.5 2.1 1.2 3.7 2.2 10.2 0.8 7.3 0.1 3.3 2.4 6.0 6.3 6.7 8.2 6.3 6.0 6.1 6.1 6.4 6.0 6.2 6.3 6.1 19.2 18.8 24.8 11.5 2.3 4.0 2.0 2.8 3.8 3.6 6.1 6.5 5.7 3.1 20.2 0.0 2.2 5.2 1.3 3.9 2.2 0.8 9.9 6.8 13.5 8.4 114.7 2.2 3.3 12.2 9.8 15.3 13.9 26.6 1.2 66.8 3.5 42.4 1.7 3.0 3.5 2.0 17.0 4.0 0.6 2.8 15.4 8.8 7.5 4.6 7.9 11.3 1.0 1.6 3.1 0.4 4.1 3.8 1.8 0.2 1.0 2.9 2.5 19.7 3.8 18.5 5.1 7.7 1.6 1.0 3.0 9.6 2.6 1.8 1.2 ERCC4 "FANCQ, RAD1, XPF" ENSG00000175595 "ERCC excision repair 4, endonuclease catalytic subunit" Q92889 16 13920154-13952348 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Cockayne syndrome, Disease variant, Dwarfism, Fanconi anemia, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 18.5" "Cell type enhanced" "Detected in many" "Early spermatids: 140.7;Late spermatids: 117.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000156, HPA045828" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Plasma membrane" "CAB000156: , HPA045828: AB_2679463" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "unprognostic (2.12e-3)" "unprognostic (9.41e-2)" "unprognostic (3.35e-1)" "unprognostic (1.40e-2)" "unprognostic (1.64e-2)" "unprognostic (2.26e-1)" "unprognostic (3.59e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (8.49e-2)" "unprognostic (5.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (6.30e-2)" "unprognostic (5.88e-4)" 2.7 3.9 4.7 3.3 5.2 2.5 2.8 6.7 5.4 3.3 4.3 1.9 1.7 3.3 2.8 2.9 3.5 3.0 3.6 4.3 4.9 2.9 3.2 2.7 3.3 5.1 4.8 4.3 2.7 3.9 1.6 2.6 4.9 3.6 2.2 4.1 2.8 2.9 18.5 3.0 1.9 3.6 4.4 3.7 2.6 5.5 5.4 4.2 4.4 3.3 2.9 2.6 1.5 6.8 4.7 5.5 5.3 7.5 8.7 8.1 4.0 6.1 6.4 5.4 6.8 2.1 4.5 7.8 8.6 5.4 4.8 5.8 8.0 4.1 8.3 10.7 4.7 3.8 6.7 5.2 7.9 5.2 4.2 6.1 5.7 7.1 6.0 5.3 7.2 4.6 6.1 8.8 7.6 3.9 7.0 3.4 3.9 2.4 3.1 7.8 10.8 9.7 3.3 3.2 4.3 5.1 7.5 6.0 5.8 4.2 7.5 3.9 7.9 7.8 5.7 7.0 5.4 7.9 9.9 5.2 7.6 6.2 8.1 4.9 2.3 2.3 2.6 2.7 2.9 2.5 2.4 2.0 2.3 3.1 2.4 2.6 2.7 3.6 2.4 3.2 2.5 1.1 4.7 5.2 6.7 5.4 4.3 4.9 5.1 4.8 4.9 4.4 5.4 6.8 14.0 19.2 13.5 16.6 11.3 4.8 6.1 18.3 10.2 0.0 10.0 9.5 8.6 14.3 12.7 5.5 0.0 17.3 9.7 3.3 9.8 11.6 140.7 18.6 19.0 13.5 9.6 12.0 20.4 8.4 6.2 13.0 5.1 7.4 1.3 17.8 17.2 17.7 11.7 0.0 21.2 4.8 10.2 13.6 6.5 117.9 14.9 11.4 10.6 8.4 14.4 0.0 17.5 12.1 20.1 9.9 1.7 21.1 14.4 10.2 4.4 13.3 26.1 0.0 26.3 17.3 12.2 49.4 28.9 9.2 5.5 12.3 11.8 18.0 6.0 4.7 ETV6 TEL ENSG00000139083 "ETS variant transcription factor 6" P41212 12 11649674-11895377 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 137.2;Microglial cells: 216.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 85.1;NB-4: 45.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000264 Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoli Cytosol "HPA000264: AB_611466" "unprognostic (4.03e-3)" "unprognostic (3.08e-2)" "unprognostic (7.54e-3)" "unprognostic (2.60e-1)" "unprognostic (2.07e-1)" "unprognostic (1.35e-3)" "unprognostic (2.74e-2)" "unprognostic (4.02e-2)" "unprognostic (3.16e-1)" "unprognostic (9.46e-2)" "prognostic unfavorable (9.38e-5)" "unprognostic (1.15e-1)" "prognostic unfavorable (4.66e-8)" "unprognostic (1.33e-2)" "unprognostic (5.99e-2)" "unprognostic (8.92e-2)" "prognostic favorable (1.54e-5)" 16.9 8.8 4.8 16.3 4.4 40.9 20.0 4.8 5.6 9.4 3.6 15.2 7.5 7.9 11.1 9.5 8.0 9.7 6.6 4.2 4.7 9.2 9.3 16.2 12.8 9.2 6.0 5.0 9.6 5.6 5.3 8.1 6.9 13.5 11.2 2.6 33.3 6.8 5.5 24.3 14.1 9.2 6.8 16.7 8.4 3.5 6.8 17.3 8.9 2.7 14.7 15.0 8.4 6.3 5.6 7.5 6.7 11.6 5.0 4.7 8.1 4.1 6.9 5.2 6.1 0.5 25.9 4.7 4.0 7.0 6.1 7.1 3.0 12.4 6.2 85.1 1.4 29.9 4.0 2.8 6.2 32.0 31.2 9.3 7.5 5.1 10.5 9.9 15.9 21.3 2.3 15.3 4.7 3.6 18.1 45.3 10.9 5.9 2.0 5.1 6.3 12.3 11.9 34.8 1.3 6.8 8.1 7.7 7.7 10.6 2.6 19.9 18.1 11.6 9.8 3.9 8.8 6.7 5.5 2.6 7.6 0.2 13.6 6.2 4.5 5.9 1.1 5.6 1.6 2.3 1.7 1.1 3.5 1.7 1.0 0.6 9.8 2.1 6.8 5.3 1.2 1.2 4.8 4.4 4.8 5.6 4.2 4.7 9.2 6.0 6.9 6.8 6.8 6.3 38.3 6.4 9.6 84.2 37.7 14.9 31.8 27.2 10.8 3.1 66.7 57.8 9.1 21.5 30.7 14.7 6.2 15.0 21.5 45.7 1.9 17.9 17.6 45.3 17.5 37.5 32.4 33.6 63.6 35.9 4.3 12.9 20.9 69.7 10.8 24.0 38.6 10.9 18.3 0.0 117.7 28.9 22.4 53.3 137.2 4.5 7.8 62.6 28.4 216.4 55.7 4.3 8.2 106.6 37.0 38.6 31.6 10.9 71.4 34.2 15.4 11.5 39.3 3.9 19.7 17.6 34.2 0.6 5.4 17.3 22.4 8.6 20.9 21.5 22.5 71.8 F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 160.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 113.6;Hepatocytes: 195.1;Leydig cells: 215.9;Peritubular cells: 236.2" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 14.4;BJ hTERT+: 11.5;CACO-2: 12.7;fHDF/TERT166: 13.1;Hep G2: 59.6;HHSteC: 11.5;SH-SY5Y: 27.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 13000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" 21.3 8.5 1.1 1.5 1.2 0.0 11.7 2.5 2.0 53.8 1.4 5.6 10.9 13.2 16.4 8.9 23.9 10.9 40.7 1.1 1.8 4.1 160.0 14.4 3.2 2.6 1.5 27.9 7.1 0.2 4.5 4.4 2.5 12.8 2.0 0.9 5.1 7.1 6.8 20.7 11.9 2.7 1.3 3.2 8.6 10.1 1.4 1.4 8.3 6.6 1.3 11.9 25.8 1.1 0.1 0.0 2.5 0.4 8.0 8.1 0.1 14.4 11.5 0.8 0.3 12.7 0.1 0.1 0.5 13.1 1.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 59.6 11.5 0.0 0.3 8.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 1.5 0.1 0.0 0.3 0.0 1.3 0.2 0.3 0.1 0.0 0.0 0.2 1.0 27.9 0.1 0.5 0.1 0.6 0.6 0.1 0.0 0.0 0.8 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 2.5 2.0 1.1 1.8 2.6 1.5 2.5 1.3 1.4 1.1 7.0 0.0 0.0 1.3 0.6 15.7 0.1 0.0 0.0 1.1 0.4 0.3 9.1 4.3 0.0 1.8 0.0 0.6 0.0 0.1 0.0 0.1 2.9 1.9 45.9 3.8 17.9 2.7 1.3 0.0 0.4 113.6 6.1 1.0 1.3 2.2 7.9 195.1 1.4 6.7 1.4 5.0 0.0 4.8 25.0 9.6 215.9 1.3 19.6 5.6 0.6 4.5 0.0 0.5 0.1 0.3 6.5 236.2 0.0 0.3 28.3 6.4 0.0 1.2 52.6 14.5 40.9 2.3 1.2 0.5 15.3 1.1 1.9 2.4 2.2 0.4 F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186266189-186289681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 243.2" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 27.6;Hepatocytes: 75.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "Hep G2: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039808 Approved Vesicles "Secreted to blood" NA NA 4400000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA039808: AB_2676693" "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.0 0.2 17.1 0.2 0.1 0.0 0.0 13.1 0.0 0.2 0.0 27.6 243.2 8.4 0.0 0.0 0.3 0.3 58.9 0.0 0.2 0.0 0.1 0.0 0.1 0.7 0.0 0.2 0.7 0.0 8.7 0.0 0.0 0.1 0.8 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.2 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 27.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.3 2.5 1.8 0.0 0.0 0.2 0.3 11.7 2.3 0.0 0.0 0.0 0.1 0.0 5.3 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.7 0.0 0.0 0.6 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.0 1.1 5.5 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 F12 ENSG00000131187 "Coagulation factor XII" P00748 5 177402141-177409564 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 226 "liver: 604.6" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 523.0" "Cancer enriched" "Detected in many" 21 "liver cancer: 171.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "classical monocyte: 1.2;eosinophil: 3.6" "Group enriched" "Detected in many" 5 "granulocytes: 3.6;monocytes: 1.2" "Cell line enhanced" "Detected in some" "HDLM-2: 7.1;MCF7: 9.0;PC-3: 6.4;SH-SY5Y: 4.3;U-937: 4.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA003825 Approved "Secreted to blood" NA NA 1040000 7000000000 "Cluster 52: Eosinophils - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" "HPA003825: AB_1078790" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (2.93e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "prognostic favorable (4.63e-5)" "unprognostic (6.97e-2)" "unprognostic (1.26e-2)" "unprognostic (3.96e-2)" "unprognostic (4.41e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (4.11e-2)" "unprognostic (3.69e-1)" "unprognostic (3.40e-6)" "unprognostic (6.48e-2)" 0.4 0.1 1.4 0.1 1.2 2.6 0.3 0.1 1.3 0.4 0.1 0.5 0.5 0.2 0.0 1.9 0.3 0.1 0.4 1.5 0.8 0.8 604.6 0.6 0.0 0.8 0.6 0.0 0.6 0.1 0.6 0.1 0.9 0.3 0.1 0.0 0.4 0.0 0.0 0.9 0.5 0.0 0.4 1.0 0.1 1.2 0.8 0.0 0.2 0.0 0.1 0.2 0.8 0.8 0.7 1.6 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 1.0 0.0 0.3 0.0 0.2 1.1 0.5 0.3 0.0 7.1 1.4 1.1 0.3 0.7 0.2 0.6 2.4 0.2 1.0 0.0 0.3 0.1 0.2 1.6 0.3 2.5 0.0 9.0 0.1 2.1 0.0 2.1 6.4 0.5 0.2 1.5 0.9 0.0 2.0 4.3 0.2 0.7 0.6 0.0 0.3 0.0 0.0 0.1 0.8 0.0 0.2 0.4 0.0 0.0 0.0 4.6 0.5 0.0 1.2 3.6 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.5 0.5 0.0 0.5 1.4 1.2 0.1 1.3 1.5 0.8 0.8 0.6 0.9 0.4 0.8 0.8 0.5 0.0 0.0 0.3 5.3 33.1 7.7 15.3 35.9 0.6 12.7 17.5 1.0 17.2 3.9 1.8 4.2 0.0 4.0 27.6 0.0 6.5 23.3 2.2 0.9 2.2 10.3 19.6 2.6 4.2 0.4 1.1 3.6 1.7 0.0 0.2 16.8 523.0 0.5 0.0 0.8 12.3 8.2 16.7 6.1 42.1 0.6 1.0 8.8 0.0 1.2 0.7 2.1 1.5 0.6 11.1 22.0 0.0 8.5 7.2 60.7 16.1 3.6 0.9 0.0 0.5 1.1 12.0 23.6 57.5 54.3 0.1 4.0 0.1 34.8 7.6 F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144084-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 232.8;placenta: 489.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 863.3;Langerhans cells: 205.1;Macrophages: 232.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 141.1;myeloid DC: 179.6" "Group enriched" "Detected in many" 184 "dendritic cells: 179.6;granulocytes: 50.2;monocytes: 141.1" "Cell line enhanced" "Detected in some" "AF22: 24.0;LHCN-M2: 8.9;RH-30: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA001804, CAB002155" Enhanced "Secreted to blood" NA NA 1400000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 4: Macrophages - Innate immune response" "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" 232.8 57.9 2.6 52.3 4.2 16.1 46.9 1.3 13.0 50.4 28.5 45.9 9.7 18.5 5.6 51.2 29.1 52.7 39.2 2.1 3.6 21.0 3.0 38.7 30.0 8.3 4.6 10.7 10.0 13.3 8.1 489.2 6.9 8.8 63.9 21.6 18.8 13.4 10.3 22.7 22.0 89.6 2.6 8.8 25.4 17.8 3.7 20.9 17.1 32.8 12.5 144.5 12.1 4.0 0.0 0.1 24.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.9 0.0 0.1 0.2 0.0 0.0 0.0 0.0 43.8 0.8 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 50.2 141.1 1.4 0.5 25.4 0.6 0.4 0.3 0.4 179.6 0.4 0.4 0.2 32.9 0.3 0.7 12.5 0.3 364.9 2.6 4.2 1.3 13.0 2.1 3.6 8.3 4.6 6.9 2.6 3.7 4.0 2.0 0.0 1.9 0.3 1.8 18.7 0.0 0.0 0.6 0.1 0.3 0.4 10.6 5.7 0.0 0.0 0.0 5.0 4.5 0.0 0.0 0.0 5.1 0.6 10.6 3.8 0.0 1.3 3.9 0.0 5.6 13.7 0.0 0.4 1.3 0.0 2.9 0.9 863.3 0.0 1.4 0.0 0.0 92.4 205.1 5.8 4.4 232.0 19.6 64.6 53.1 0.9 6.2 0.5 0.7 0.1 0.0 0.7 1.2 0.0 0.0 11.0 2.2 6.5 59.2 2.5 3.3 1.6 0.9 1.2 15.2 10.1 2.6 0.4 0.0 0.1 F13B FXIIIB ENSG00000143278 "Coagulation factor XIII B chain" P05160 1 197038741-197067260 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 211 "liver: 200.2" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 54.9" "Cancer enriched" "Detected in single" 816 "liver cancer: 46.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003827, HPA052139" Supported "Secreted to blood" NA NA 4700000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "HPA003827: AB_1078794, HPA052139: AB_2681744" "unprognostic (1.46e-1)" "prognostic favorable (6.78e-5)" "unprognostic (1.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 200.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 54.9 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 F2 ENSG00000180210 "Coagulation factor II, thrombin" P00734 11 46719196-46739506 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1518 "liver: 1217.3" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 991.0" "Cancer enriched" "Detected in some" 110 "liver cancer: 508.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "Hep G2: 281.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016780, HPA051476, HPA054698" Enhanced "Secreted to blood" NA NA 108000000000 41000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016780: , HPA051476: AB_2681498, HPA054698: AB_2682578" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" "unprognostic (2.81e-1)" "unprognostic (2.23e-2)" "unprognostic (3.94e-2)" "unprognostic (5.79e-2)" "unprognostic (8.29e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.75e-12)" "unprognostic (5.65e-3)" "unprognostic (5.80e-2)" "unprognostic (1.54e-3)" 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.2 1217.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.9 0.0 0.2 2.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.2 281.0 0.0 1.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.3 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.2 0.0 37.5 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 21.8 991.0 0.0 0.0 0.2 0.2 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.0 0.0 0.0 0.1 F5 ENSG00000198734 "Coagulation factor V" P12259 1 169511951-169586588 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 142.8;liver: 176.2;placenta: 46.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Cytotrophoblasts: 82.7;Hepatocytes: 253.4;Syncytiotrophoblasts: 59.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 69.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "classical monocyte: 4.1;eosinophil: 8.1;neutrophil: 7.0;T-reg: 6.2" "Group enriched" "Detected in many" 13 "granulocytes: 8.1;monocytes: 4.1;T-cells: 6.2" "Group enriched" "Detected in some" 23 "Hep G2: 32.8;OE19: 125.5" "Group enriched" "Detected in many" 5 "basal ganglia: 2.7;hippocampal formation: 6.6;pons and medulla: 4.4;thalamus: 5.4" "Group enriched" "Detected in all" 7 "amygdala: 39.9;basal ganglia: 35.0;cerebral cortex: 67.9;hippocampal formation: 61.4;olfactory bulb: 27.6" HPA002036 Approved "Golgi apparatus" "Secreted to blood" NA NA 7670000000 13000000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA002036: AB_1078787" "unprognostic (3.67e-2)" "unprognostic (2.77e-4)" "unprognostic (5.42e-2)" "unprognostic (2.56e-4)" "unprognostic (2.03e-1)" "unprognostic (2.39e-4)" "unprognostic (3.46e-3)" "unprognostic (9.25e-3)" "unprognostic (2.02e-1)" "unprognostic (8.99e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.15e-2)" "unprognostic (3.41e-1)" "unprognostic (4.31e-1)" 1.1 0.0 0.3 3.2 1.4 3.7 0.6 4.4 1.3 0.1 142.8 0.3 0.9 0.1 0.2 0.2 3.5 17.6 2.7 4.4 1.6 1.5 176.2 0.9 2.2 1.9 2.2 0.0 0.8 0.0 1.6 46.9 2.4 1.3 0.6 1.0 6.2 0.0 0.2 1.3 0.3 1.1 0.8 1.8 4.9 0.5 2.2 0.5 0.4 0.2 2.3 3.8 0.1 4.2 0.0 0.6 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 32.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 125.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.1 8.1 0.0 0.2 0.0 0.0 1.4 0.2 0.4 0.0 0.3 0.0 7.0 0.0 0.0 0.0 6.2 1.1 0.3 1.4 4.4 1.3 4.4 1.6 1.9 2.2 2.4 0.8 2.2 4.2 0.0 3.2 0.6 1.6 0.7 0.1 6.1 0.0 0.0 0.3 0.7 0.3 9.4 74.4 1.9 0.0 2.1 82.7 0.1 0.3 0.0 2.4 2.4 0.9 0.0 2.4 25.2 0.0 5.4 0.2 2.3 5.3 4.1 0.2 0.0 2.8 3.6 253.4 5.3 0.0 2.6 0.1 0.0 12.3 0.4 0.3 0.0 7.1 3.6 0.0 18.2 1.0 2.1 0.5 1.0 1.9 0.0 0.0 0.1 1.8 0.0 0.2 3.1 0.1 0.0 2.4 0.2 0.5 0.5 0.0 0.0 59.5 2.5 0.0 0.0 11.8 F7 ENSG00000057593 "Coagulation factor VII" P08709 13 113105788-113120685 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "liver: 160.2" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 149.3" "Cancer enriched" "Detected in some" 17 "liver cancer: 41.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "CACO-2: 11.5;Hep G2: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA004826 Approved Mitochondria "Secreted to blood" NA NA 351000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA004826: AB_10602805" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-3)" "unprognostic (3.81e-1)" "unprognostic (4.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.35e-3)" "unprognostic (3.36e-3)" "unprognostic (1.09e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" 0.2 0.0 0.4 0.1 0.3 0.0 0.2 0.5 0.7 1.1 0.2 0.1 0.5 0.1 0.6 0.1 0.5 0.0 0.2 0.3 0.7 0.4 160.2 0.1 0.0 0.3 0.5 0.4 0.1 0.2 0.4 0.1 0.3 0.4 0.0 0.2 0.3 0.0 0.0 0.4 0.8 0.0 0.2 0.1 0.1 1.5 0.6 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.5 0.7 0.3 0.7 0.3 0.5 0.3 0.2 0.6 0.3 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.6 0.3 0.5 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.0 8.0 0.3 0.2 0.0 0.4 0.0 0.2 0.0 0.3 2.2 149.3 0.1 0.0 0.5 0.4 0.0 2.8 0.7 0.2 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 1.1 0.3 0.0 0.2 0.0 0.5 0.1 3.2 4.1 0.0 0.1 0.1 0.2 0.1 0.3 0.0 F8 "DXS1253E, F8C, FVIII, HEMA" ENSG00000185010 "Coagulation factor VIII" P00451 X 154835788-155026940 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Hemophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 53.2" "Group enriched" "Detected in many" 10 "Adipocytes: 118.6;Endothelial cells: 120.4;Hepatic stellate cells: 371.2" "Cancer enhanced" "Detected in all" "renal cancer: 7.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 16.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB018777 Enhanced "Secreted to blood" NA NA 25000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB018777: AB_640320" "unprognostic (2.09e-1)" "unprognostic (5.66e-4)" "unprognostic (4.94e-2)" "unprognostic (8.32e-5)" "unprognostic (1.26e-1)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" "unprognostic (8.27e-2)" "unprognostic (6.58e-2)" "unprognostic (1.68e-1)" "unprognostic (1.67e-2)" "unprognostic (5.58e-2)" "unprognostic (1.24e-2)" "unprognostic (2.16e-3)" "unprognostic (1.69e-1)" "unprognostic (1.17e-2)" "unprognostic (4.44e-2)" 29.4 15.2 7.8 2.5 8.6 2.1 19.3 7.4 11.2 7.5 9.9 9.6 2.9 10.9 9.1 4.0 7.9 5.0 53.2 8.2 8.5 14.1 20.1 16.7 4.7 8.6 8.4 14.5 11.6 5.6 6.4 3.3 8.6 9.0 3.8 6.2 4.7 7.5 20.6 3.6 5.0 6.3 7.8 17.9 5.7 6.1 8.9 3.2 10.9 28.1 3.7 8.1 3.7 7.8 6.1 4.5 0.9 2.1 6.5 10.1 0.7 2.9 1.8 2.0 3.4 0.3 6.8 12.0 9.5 3.0 4.7 0.8 1.0 1.0 1.8 5.1 1.9 2.4 2.8 0.2 3.0 2.1 5.6 7.2 0.6 1.8 2.4 3.5 1.2 5.7 1.1 9.0 10.0 2.7 1.7 1.9 1.6 1.8 4.5 1.4 1.5 1.8 1.8 1.3 3.7 2.8 7.0 0.8 3.9 1.0 2.1 4.9 1.5 10.3 5.5 16.6 3.7 5.3 5.1 6.0 9.4 12.3 5.5 4.6 2.8 0.9 5.2 2.4 10.3 2.1 3.1 5.5 2.7 1.9 1.6 4.1 4.4 3.3 2.4 0.4 4.6 2.7 7.8 8.6 7.4 11.2 8.2 8.5 8.6 8.4 8.6 7.8 8.9 7.8 118.6 0.0 6.3 13.1 2.3 1.8 2.5 1.6 4.0 8.1 3.7 4.2 17.7 7.2 1.9 3.7 2.1 0.9 2.0 0.6 7.9 3.1 1.4 1.5 1.5 120.4 0.0 8.4 7.2 0.7 0.7 6.8 0.0 1.5 1.3 8.2 371.2 11.8 3.2 6.7 5.0 0.6 0.0 19.9 1.1 3.3 11.5 3.0 0.0 8.4 2.4 6.8 2.1 7.5 6.0 4.5 0.1 5.3 2.0 1.4 0.9 11.4 2.4 3.5 6.6 11.1 13.0 2.3 3.4 1.5 1.1 0.1 4.0 4.3 0.4 2.1 F9 FIX ENSG00000101981 "Coagulation factor IX" P00740 X 139530739-139563459 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets, Hemophilia, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2467 "liver: 704.9" "Cell type enriched" "Detected in some" 32 "Hepatocytes: 609.1" "Cancer enriched" "Detected in single" 1354 "liver cancer: 67.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 8200000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 15: Hepatocytes - Hemostasis" "prognostic favorable (6.69e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 704.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 609.1 0.0 0.0 0.1 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "FA complementation group A" O15360 16 89737549-89816657 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.2;testis: 21.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 44.1;Spermatogonia: 38.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA063236: AB_2684966" "unprognostic (5.99e-2)" "unprognostic (5.68e-2)" "unprognostic (2.36e-1)" "unprognostic (5.12e-2)" "unprognostic (1.87e-1)" "unprognostic (7.11e-2)" "unprognostic (1.45e-4)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (4.82e-3)" "unprognostic (8.48e-4)" "unprognostic (7.82e-10)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" 1.4 1.9 1.7 6.7 1.9 20.2 1.9 2.4 3.3 2.1 1.5 5.5 5.2 1.2 0.8 6.6 2.0 1.2 1.6 1.8 1.2 2.9 6.1 3.4 12.5 1.4 1.1 1.4 1.9 1.4 1.9 4.1 1.5 1.7 6.2 1.0 2.1 0.6 0.7 5.2 5.6 2.1 1.1 6.7 3.6 21.6 1.5 8.1 1.7 0.6 13.5 2.2 2.7 1.9 23.2 34.8 40.8 35.7 2.6 5.2 31.2 28.2 15.3 46.5 19.5 30.6 37.3 56.2 12.9 9.8 15.5 34.7 27.7 21.1 48.8 13.4 46.5 16.6 49.1 63.4 1.7 17.1 17.5 1.7 2.2 37.8 12.0 6.6 14.9 28.0 40.9 16.9 24.6 53.6 34.6 73.7 26.5 31.5 21.3 61.4 32.8 10.3 11.8 21.5 36.3 19.7 41.9 12.3 5.4 23.3 22.4 30.4 11.1 37.0 38.9 20.9 30.0 15.1 19.0 56.3 17.5 37.8 36.1 2.5 7.4 9.9 4.2 8.5 3.0 7.0 2.4 3.7 6.2 4.6 0.6 2.6 9.4 8.2 9.2 0.4 9.2 4.2 1.7 1.9 2.4 3.3 1.8 1.2 1.4 1.1 1.5 1.1 1.5 1.9 1.5 0.0 1.1 0.7 9.6 3.4 1.6 2.6 0.0 8.1 3.0 2.0 2.9 0.0 3.5 16.5 10.4 16.0 12.3 5.1 1.9 2.0 5.9 2.8 3.5 2.1 1.8 20.8 10.0 1.6 9.9 3.3 9.2 3.4 2.5 19.0 5.3 4.7 8.8 3.3 5.7 8.1 2.0 4.1 3.1 4.1 1.5 6.8 0.0 1.0 3.0 1.1 21.6 3.0 1.7 1.9 1.7 0.0 21.1 1.3 6.6 10.4 6.4 7.7 0.0 2.7 3.5 44.1 38.5 3.8 1.8 25.3 9.3 6.8 11.4 2.6 FANCB "FAAP95, FAB, FLJ34064" ENSG00000181544 "FA complementation group B" Q8NB91 X 14835961-14873069 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.4;brain: 3.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 12.4;Oligodendrocytes: 33.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003124 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA003124: AB_1078813" "unprognostic (3.49e-2)" "unprognostic (1.92e-3)" "unprognostic (1.16e-2)" "unprognostic (8.42e-3)" "unprognostic (7.99e-2)" "unprognostic (2.42e-2)" "unprognostic (4.05e-5)" "unprognostic (6.93e-3)" "unprognostic (1.77e-3)" "unprognostic (7.70e-3)" "unprognostic (2.76e-4)" "unprognostic (1.03e-1)" "unprognostic (1.25e-11)" "unprognostic (4.46e-2)" "unprognostic (1.92e-1)" "unprognostic (6.88e-2)" "unprognostic (5.96e-2)" 0.2 0.1 2.1 0.7 3.3 3.4 0.5 1.2 1.6 0.3 0.0 0.3 0.2 0.3 0.1 0.4 0.2 0.1 0.1 0.8 1.0 0.1 0.1 0.2 1.2 1.7 2.2 0.4 0.1 0.1 0.0 0.8 1.8 0.2 0.5 0.0 0.2 0.1 0.1 0.3 0.2 0.3 1.5 0.4 0.2 0.2 3.1 1.4 0.2 0.1 1.3 0.3 0.3 3.8 7.3 5.0 4.8 3.9 0.3 1.1 1.7 11.2 3.0 8.8 9.9 3.5 5.3 10.6 1.9 4.4 6.6 7.0 11.3 4.1 15.0 5.1 5.9 4.1 7.9 1.7 0.1 5.8 3.3 0.1 0.4 9.0 2.0 0.9 4.4 3.5 7.3 7.2 5.2 3.5 5.7 3.2 6.1 3.0 7.1 5.1 11.4 5.2 0.8 2.6 3.1 3.5 5.7 2.4 3.2 11.2 3.6 2.0 1.8 6.7 3.7 14.5 6.8 1.8 3.9 7.2 3.0 4.1 14.3 0.3 0.2 0.2 0.2 0.1 0.1 0.7 0.1 0.3 0.2 0.5 0.1 0.1 0.4 0.4 0.1 0.2 0.4 0.2 2.1 3.3 1.2 1.6 0.8 1.0 1.7 2.2 1.8 1.5 3.1 3.8 1.9 3.2 0.5 1.0 5.2 1.7 1.1 1.5 0.6 3.0 1.6 3.3 0.4 0.0 1.8 0.0 0.0 7.0 6.2 0.9 0.0 1.2 0.4 2.1 2.7 1.9 0.0 5.0 6.3 1.5 12.4 2.0 1.5 2.3 3.8 6.6 1.4 0.3 3.6 3.3 4.8 0.8 4.1 0.3 1.8 0.6 1.2 2.7 0.0 2.8 1.0 0.4 3.1 3.0 33.1 0.7 0.1 1.2 6.5 0.7 0.2 0.4 1.2 0.5 0.0 2.4 2.3 5.2 4.2 3.8 1.0 3.8 4.1 0.7 1.8 1.5 FANCC "FA3, FAC, FACC" ENSG00000158169 "FA complementation group C" Q00597 9 95099054-95426796 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 24.6" "Cell type enhanced" "Detected in many" "Early spermatids: 178.6;Hepatocytes: 42.6;Late spermatids: 87.8;Microglial cells: 49.6;Oligodendrocytes: 48.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 8.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.8" "Cell line enhanced" "Detected in all" "RH-30: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017793, HPA030771" Approved Supported Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "CAB017793: , HPA030771: AB_2673604" "unprognostic (1.48e-2)" "unprognostic (4.33e-2)" "unprognostic (1.10e-1)" "unprognostic (2.63e-1)" "unprognostic (2.14e-1)" "unprognostic (1.32e-2)" "unprognostic (3.41e-3)" "unprognostic (1.26e-2)" "unprognostic (7.45e-3)" "unprognostic (1.37e-1)" "unprognostic (8.00e-3)" "unprognostic (3.19e-2)" "prognostic favorable (6.03e-6)" "unprognostic (2.35e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (5.71e-2)" 2.6 1.7 1.7 3.1 2.4 3.3 3.4 8.9 2.7 4.1 1.7 4.0 5.5 3.2 1.1 3.5 2.8 3.7 2.7 1.8 2.3 6.8 24.6 4.0 2.7 3.9 2.3 2.3 4.4 1.5 3.5 3.1 3.2 3.5 4.3 2.4 3.0 1.5 3.6 5.9 6.2 2.1 1.7 2.3 3.6 9.5 2.4 4.2 3.1 1.2 2.6 3.0 3.2 3.9 21.5 14.6 18.7 16.9 2.0 5.4 11.7 8.1 5.7 14.1 13.9 16.2 9.3 12.7 6.4 7.2 10.6 25.5 21.1 8.5 8.4 12.9 10.1 9.8 16.6 9.6 2.7 11.6 11.3 4.9 3.8 11.1 5.4 3.9 8.4 10.1 14.9 5.7 10.3 17.1 9.7 5.8 9.6 23.2 8.9 17.3 47.1 7.0 6.4 6.8 26.2 13.1 18.9 7.4 4.2 8.2 6.9 8.6 4.0 13.0 17.1 14.5 14.1 5.9 12.0 6.8 6.6 9.8 15.9 8.8 0.3 0.0 0.9 0.6 0.9 0.6 0.4 0.9 0.3 0.6 0.7 0.7 0.1 0.1 1.3 0.9 0.4 0.5 1.7 2.4 8.9 2.7 1.8 2.3 3.9 2.3 3.2 1.7 2.4 3.9 3.0 3.2 2.2 9.4 2.2 2.5 2.7 1.2 2.8 6.1 3.5 3.7 1.9 5.7 2.3 0.0 4.2 3.0 2.7 3.3 1.9 4.4 178.6 3.5 5.5 4.3 0.0 3.0 22.1 4.1 5.0 3.3 2.0 4.7 5.7 3.9 5.0 42.6 2.0 10.1 13.8 4.0 0.0 3.5 1.3 87.8 6.5 1.6 1.8 49.6 2.8 2.1 1.0 32.2 48.9 3.1 1.0 2.2 4.4 3.0 5.6 8.9 1.0 4.5 0.0 4.1 2.3 19.4 13.2 4.0 2.7 2.3 2.1 4.5 4.7 2.5 FANCD2 "FA-D2, FACD, FAD, FANCD" ENSG00000144554 "FA complementation group D2" Q9BXW9 3 10026414-10101932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Spermatocytes: 62.5;Spermatogonia: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 120.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016117, HPA063742" Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" No No "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB016117: AB_2278211, HPA063742: AB_2685110" "unprognostic (3.25e-2)" "unprognostic (1.09e-1)" "unprognostic (6.21e-2)" "unprognostic (1.12e-2)" "unprognostic (2.92e-1)" "unprognostic (3.36e-2)" "unprognostic (1.08e-5)" "unprognostic (2.96e-2)" "unprognostic (1.59e-3)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.23e-2)" "unprognostic (9.14e-2)" "unprognostic (4.41e-10)" "unprognostic (9.11e-3)" "unprognostic (3.99e-1)" "unprognostic (7.76e-2)" "unprognostic (2.89e-2)" 1.1 0.7 2.7 7.7 2.1 17.8 3.4 1.6 5.3 1.5 1.1 4.0 3.2 2.0 0.7 2.5 2.6 2.0 0.5 3.4 1.6 0.9 1.1 1.9 12.2 3.9 1.4 3.6 0.8 0.8 0.5 4.7 3.0 1.9 6.4 3.1 4.9 1.0 4.8 4.5 4.0 2.0 2.4 6.4 3.5 11.8 2.3 9.8 1.9 0.4 13.0 2.3 1.3 5.1 24.1 25.4 46.5 13.2 2.4 3.5 120.7 22.0 9.8 31.3 25.4 18.8 23.0 46.7 9.8 7.0 25.1 20.2 48.8 16.7 31.0 22.6 33.0 63.6 39.6 17.9 0.4 48.1 37.9 1.2 2.6 34.1 18.4 4.2 18.4 39.3 39.6 51.6 23.1 27.2 40.6 17.9 56.1 18.1 17.6 43.4 37.7 32.5 10.3 26.7 13.0 25.3 26.4 20.1 8.3 33.5 31.0 29.4 10.6 24.6 28.4 15.1 31.5 21.7 46.4 77.2 14.1 47.7 43.2 2.7 0.6 1.9 0.6 0.5 0.6 2.4 0.9 0.5 0.4 3.2 1.1 0.9 1.5 1.0 1.4 1.8 1.5 0.5 2.7 2.1 1.6 5.3 3.4 1.6 3.9 1.4 3.0 2.4 2.3 5.1 0.7 0.0 0.5 0.7 12.5 4.6 3.5 2.9 2.8 3.1 4.5 2.7 2.0 1.5 1.9 1.8 10.4 12.7 5.6 3.1 0.0 1.9 5.9 2.6 1.5 2.1 1.2 25.2 3.0 3.5 15.2 2.6 2.0 3.4 1.3 11.8 3.3 1.5 5.7 0.0 2.6 3.2 6.1 3.8 7.0 8.0 2.1 3.7 3.6 1.9 4.9 0.6 1.0 1.5 2.4 1.8 3.6 1.5 8.1 2.2 0.5 0.7 2.0 5.6 19.7 2.6 2.1 62.5 30.2 4.1 2.7 7.0 5.2 1.6 7.6 3.1 FANCE "FACE, FAE" ENSG00000112039 "FA complementation group E" Q9HB96 6 35452338-35467102 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 22.1;Extravillous trophoblasts: 104.8;Syncytiotrophoblasts: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB014893 Enhanced Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 32: U-937 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB014893: " "unprognostic (2.66e-1)" "unprognostic (8.01e-3)" "unprognostic (7.73e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.80e-3)" "prognostic unfavorable (2.08e-9)" "unprognostic (8.90e-2)" "unprognostic (5.70e-3)" "unprognostic (8.41e-2)" "unprognostic (1.52e-1)" "unprognostic (2.91e-2)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (3.05e-1)" "unprognostic (2.44e-2)" "unprognostic (5.14e-2)" 4.6 1.5 2.6 3.2 2.5 5.8 5.0 2.8 3.1 7.1 2.0 3.1 2.1 3.7 3.4 8.6 4.8 1.5 3.3 2.3 2.9 2.1 1.3 4.1 4.5 2.7 2.6 7.8 3.5 4.0 3.1 9.3 2.6 3.8 3.0 1.8 4.3 2.7 11.0 13.8 3.5 3.1 2.4 3.8 3.4 8.7 2.7 2.6 3.0 3.1 5.7 4.0 7.7 2.7 9.9 4.2 12.8 27.6 9.2 15.9 34.6 11.4 9.6 14.8 12.1 11.1 5.3 33.0 7.5 6.7 11.2 7.2 13.7 9.8 13.9 11.0 11.9 23.8 11.7 6.8 4.8 12.6 8.2 10.1 28.6 17.7 27.7 3.9 8.7 12.6 21.3 11.6 12.2 11.4 5.8 16.6 4.7 10.6 7.0 18.8 12.3 12.1 3.1 10.0 12.1 11.4 6.4 9.1 10.0 11.9 8.8 43.7 5.6 16.7 14.5 10.9 18.1 7.4 29.3 11.6 3.9 24.3 16.8 0.0 0.2 0.2 0.4 0.1 0.7 0.1 0.6 0.9 0.1 0.5 0.3 0.3 0.0 0.5 0.1 0.4 0.3 0.2 2.6 2.5 2.8 3.1 2.3 2.9 2.7 2.6 2.6 2.4 2.7 2.7 7.0 6.4 0.0 1.0 2.4 8.8 4.1 4.7 1.8 1.1 2.0 2.8 2.7 0.0 1.6 0.0 0.0 22.1 2.0 1.6 0.0 1.7 0.3 1.9 2.4 3.7 1.2 2.5 0.4 0.8 104.8 2.8 1.1 3.4 0.0 5.2 1.4 0.7 6.0 0.0 0.9 3.6 0.0 0.8 1.3 0.6 1.5 1.4 1.8 2.8 0.5 1.9 1.0 0.5 1.0 1.1 0.4 0.7 3.1 5.8 1.1 0.3 0.1 2.0 0.0 4.0 3.4 8.2 13.2 4.6 7.1 46.7 2.2 3.4 4.4 3.5 FANCF FAF ENSG00000183161 "FA complementation group F" Q9NPI8 11 22622533-22625823 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Distal tubular cells: 45.0;Early spermatids: 168.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008899 Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA008899: " "unprognostic (1.16e-2)" "unprognostic (4.10e-2)" "unprognostic (2.33e-2)" "unprognostic (1.37e-2)" "unprognostic (4.55e-2)" "unprognostic (8.84e-2)" "prognostic unfavorable (2.27e-4)" "unprognostic (4.29e-2)" "unprognostic (1.11e-1)" "unprognostic (2.74e-3)" "unprognostic (3.95e-1)" "unprognostic (1.67e-1)" "unprognostic (2.29e-1)" "unprognostic (3.73e-2)" "unprognostic (1.81e-1)" "unprognostic (9.14e-2)" "unprognostic (7.64e-3)" 2.1 3.8 3.8 5.6 3.8 2.8 5.2 4.1 3.9 4.9 6.1 5.6 7.9 3.9 8.5 2.8 8.9 3.2 3.6 3.5 4.2 5.0 4.2 3.4 8.2 4.2 4.3 6.1 8.1 4.9 3.7 3.0 3.9 4.6 5.9 5.1 6.1 4.8 1.2 5.1 7.6 2.5 4.1 6.3 7.1 4.9 4.6 9.3 5.6 1.1 7.7 3.5 2.1 4.5 2.3 6.7 8.6 9.5 4.5 5.4 3.5 4.3 5.3 5.0 5.5 4.3 3.5 11.3 1.2 4.5 8.9 9.6 7.2 7.5 2.5 18.5 3.3 4.3 2.7 7.0 5.2 8.0 4.6 5.2 14.1 1.7 7.7 8.5 8.1 15.9 10.9 13.8 3.2 7.0 20.4 7.5 9.8 19.2 8.4 17.0 4.1 12.8 9.7 8.7 32.0 15.1 2.4 7.7 7.8 9.2 15.5 7.1 5.7 5.0 5.1 9.3 6.4 8.0 11.0 3.4 8.1 3.2 11.8 12.3 7.6 16.8 15.3 8.1 18.0 16.1 14.3 14.9 9.2 20.9 19.3 16.2 1.1 15.0 8.7 13.5 10.7 10.6 3.8 3.8 4.1 3.9 3.5 4.2 4.2 4.3 3.9 4.1 4.6 4.5 4.7 3.2 2.2 2.3 13.9 3.3 6.2 8.8 6.8 15.2 7.1 6.0 5.7 18.6 6.3 3.7 10.4 11.6 15.3 10.2 45.0 18.8 168.1 14.1 6.8 6.3 3.5 8.0 2.6 18.7 7.5 5.4 10.7 6.8 2.5 9.6 6.4 10.7 6.9 16.8 3.3 16.5 10.2 6.9 2.6 25.5 9.6 6.7 5.4 5.6 11.3 13.1 22.6 0.5 6.2 10.7 10.3 9.8 7.1 5.6 13.2 22.5 24.4 18.0 6.6 3.2 5.3 23.1 16.7 10.1 2.3 2.3 11.2 11.1 15.8 2.4 FANCG "FAG, XRCC9" ENSG00000221829 "FA complementation group G" O15287 9 35073835-35079942 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 20.6;Spermatogonia: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008105, HPA045335" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" Nucleoli "CAB008105: AB_2231542, HPA045335: AB_2679292" "unprognostic (9.41e-2)" "unprognostic (2.62e-2)" "unprognostic (1.82e-1)" "unprognostic (1.05e-1)" "unprognostic (2.09e-1)" "unprognostic (5.83e-3)" "prognostic unfavorable (2.02e-4)" "unprognostic (8.92e-2)" "unprognostic (1.42e-2)" "unprognostic (2.27e-3)" "unprognostic (9.01e-2)" "unprognostic (5.62e-2)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.14e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" 3.4 3.1 2.8 5.1 2.8 12.4 4.5 3.6 3.8 5.1 2.1 4.3 4.9 4.2 2.3 5.9 5.8 3.3 1.9 2.7 2.7 3.9 2.9 3.3 7.7 2.8 2.7 6.2 6.3 4.7 3.0 4.5 2.7 3.9 4.0 2.4 4.3 4.1 2.3 6.5 4.6 4.5 2.5 5.5 4.1 6.4 2.7 12.2 4.0 1.7 6.9 3.5 4.6 3.4 34.7 40.7 30.4 28.3 6.4 10.2 25.0 23.6 16.3 44.9 42.5 20.1 21.2 33.4 15.8 7.7 33.1 20.5 25.3 22.0 17.6 38.7 14.8 24.5 45.5 13.2 1.8 24.5 26.9 8.1 4.1 39.5 18.2 8.0 23.8 40.7 15.7 44.3 23.5 31.5 43.2 34.5 32.5 26.4 30.1 43.8 35.2 23.1 10.9 14.6 14.4 26.1 15.7 22.3 8.3 13.4 28.4 17.2 13.4 21.0 42.8 28.3 33.1 12.4 24.0 20.6 19.2 18.5 30.1 10.5 0.7 6.7 6.1 2.2 5.3 5.6 4.8 4.6 1.9 5.4 3.6 3.8 1.1 7.8 2.0 4.2 8.2 3.1 2.8 2.8 3.6 3.8 2.7 2.7 2.8 2.7 2.7 2.5 2.7 3.4 3.2 3.2 4.6 6.8 4.9 4.5 6.1 3.9 10.2 4.7 5.9 5.0 1.5 2.8 3.3 3.7 4.2 15.0 4.1 3.0 3.9 4.9 0.4 2.3 3.8 4.4 1.8 11.6 3.0 2.3 20.6 5.1 1.5 3.6 14.0 10.3 4.2 1.1 7.7 5.0 3.3 4.1 2.0 1.3 4.7 0.6 3.4 2.3 3.6 1.0 2.8 4.0 3.1 0.5 4.1 1.9 2.4 4.1 14.1 4.4 3.5 2.3 1.3 3.1 0.0 3.0 3.9 14.7 20.7 8.5 2.6 6.6 4.9 2.8 6.7 5.2 FANCI "FLJ10719, KIAA1794" ENSG00000140525 "FA complementation group I" Q9NVI1 15 89243945-89317261 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.4;lymphoid tissue: 44.2;testis: 32.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.6;Spermatocytes: 69.5;Spermatogonia: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 23.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039972, HPA040379" Approved Enhanced Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA039972: AB_10673265, HPA040379: AB_2676951" "unprognostic (6.88e-2)" "unprognostic (1.37e-2)" "unprognostic (1.66e-1)" "unprognostic (2.50e-2)" "unprognostic (2.99e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.82e-3)" "unprognostic (1.15e-2)" "unprognostic (4.59e-3)" "prognostic unfavorable (3.59e-4)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.71e-13)" "unprognostic (2.40e-2)" "unprognostic (2.72e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-1)" 3.2 2.1 1.6 13.0 1.3 31.4 6.0 3.8 2.5 3.3 0.0 10.5 6.0 4.7 1.1 8.1 3.4 3.0 1.7 1.7 0.7 1.7 2.9 3.4 23.9 1.2 0.9 3.8 3.0 3.0 0.6 11.3 1.7 3.6 12.4 5.4 2.8 2.0 0.8 8.0 7.3 6.9 0.6 6.0 6.7 32.6 1.3 44.2 2.0 0.8 26.6 5.4 3.7 1.7 108.2 122.4 127.8 86.1 10.8 16.0 78.5 101.4 58.3 123.6 150.5 96.8 95.4 198.8 53.4 33.8 79.3 143.9 196.8 69.0 116.2 127.8 123.5 197.2 176.7 45.8 1.7 146.0 96.3 8.6 6.8 87.1 44.4 17.6 51.7 120.2 139.2 142.3 83.5 61.5 150.9 49.6 101.1 70.3 44.5 130.6 187.1 84.6 28.5 196.8 93.9 80.8 105.2 73.3 46.7 85.7 81.2 64.8 35.4 103.2 103.8 94.9 155.8 93.3 209.5 151.9 38.5 125.7 104.7 23.4 2.3 3.0 4.7 3.0 2.8 3.5 4.7 6.5 2.2 3.6 3.3 5.6 3.1 5.1 4.3 4.1 11.8 3.1 1.6 1.3 3.8 2.5 1.7 0.7 1.2 0.9 1.7 0.6 1.3 1.7 2.6 3.2 1.5 3.6 3.8 4.2 2.6 4.0 0.6 2.4 2.9 2.7 3.9 0.0 3.3 1.8 0.0 17.0 3.9 4.2 0.0 2.0 7.9 5.0 3.7 3.0 1.2 48.6 7.0 2.9 18.3 3.9 5.6 4.5 2.5 14.9 6.8 0.8 8.1 1.7 5.8 5.9 0.0 3.0 3.8 7.9 3.4 4.8 1.8 1.9 3.3 11.6 1.0 9.0 6.9 2.5 1.2 1.5 13.9 2.0 1.3 1.0 6.3 1.9 6.6 3.6 4.0 69.5 60.2 9.2 2.4 12.4 8.1 2.5 9.1 2.8 FANCL "FAAP43, FLJ10335, PHF9, Pog" ENSG00000115392 "FA complementation group L" Q9NW38 2 58159243-58241372 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 81.4;Oligodendrocytes: 188.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033842, HPA036685, HPA036686" Supported Approved "Nuclear bodies,Vesicles" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies" Vesicles "CAB033842: AB_1122766, HPA036685: AB_10672474, HPA036686: AB_10670844" "unprognostic (3.02e-1)" "unprognostic (5.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-3)" "unprognostic (6.24e-2)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.81e-7)" "unprognostic (4.71e-2)" "unprognostic (2.63e-2)" "unprognostic (1.31e-2)" "unprognostic (3.50e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (1.12e-7)" "unprognostic (1.50e-1)" "unprognostic (1.39e-1)" "unprognostic (9.08e-3)" "prognostic favorable (7.80e-5)" 8.5 35.3 39.4 11.0 49.5 15.1 19.5 35.3 39.4 18.6 27.2 12.1 11.5 19.9 18.4 11.5 13.9 12.0 13.0 34.1 45.1 12.2 21.7 9.6 14.8 51.6 40.3 24.8 14.5 14.0 44.3 12.5 55.4 14.7 14.8 24.6 18.7 10.7 9.1 17.9 12.8 13.5 40.9 16.8 13.1 19.1 41.2 13.2 17.1 9.1 12.6 11.7 14.6 68.6 48.6 35.0 69.4 34.0 11.9 15.1 36.9 34.8 21.5 33.8 43.5 30.9 59.4 33.4 43.8 11.4 46.3 27.5 39.0 26.4 56.0 78.8 61.7 54.8 49.5 42.1 13.0 53.3 29.0 11.8 12.4 24.8 9.7 29.9 27.0 23.5 51.9 29.6 23.2 24.6 18.9 65.8 75.2 77.4 7.2 35.2 52.5 26.1 29.9 47.2 78.1 39.3 49.5 20.2 33.8 37.0 18.7 35.4 15.9 30.0 45.0 22.3 39.0 30.4 20.6 19.7 63.7 35.7 46.6 3.2 3.0 4.9 3.7 5.6 3.0 9.1 3.2 4.2 5.9 9.3 1.0 2.3 0.8 7.6 4.3 5.3 4.8 2.2 39.4 49.5 35.3 39.4 34.1 45.1 51.6 40.3 55.4 40.9 41.2 68.6 16.7 19.2 20.0 18.6 9.4 10.3 13.9 26.1 11.4 16.6 12.5 15.4 16.4 8.6 16.1 9.2 4.2 29.1 4.8 7.2 11.7 9.7 2.5 11.1 15.8 14.8 9.0 14.5 45.0 4.2 14.0 12.2 15.3 6.2 10.8 25.8 13.2 12.5 10.9 8.4 38.4 15.0 30.5 6.3 4.6 3.6 10.8 7.0 26.6 34.7 6.8 22.8 3.1 81.4 188.9 4.6 13.3 14.3 9.7 6.2 21.7 5.7 23.2 18.7 13.1 10.8 12.4 52.6 37.9 9.5 6.8 7.4 5.6 13.2 16.0 9.3 FANCM "FAAP250, KIAA1596" ENSG00000187790 "FA complementation group M" Q8IYD8 14 45135930-45200890 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 65.5;Late spermatids: 206.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055144 Supported Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA055144: AB_2682715" "unprognostic (8.40e-2)" "unprognostic (6.70e-2)" "unprognostic (3.99e-2)" "unprognostic (4.32e-2)" "unprognostic (2.15e-1)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (1.18e-1)" "unprognostic (1.57e-2)" "unprognostic (8.52e-2)" "unprognostic (1.14e-1)" "unprognostic (1.23e-2)" "unprognostic (7.55e-2)" "unprognostic (2.90e-1)" "unprognostic (1.71e-1)" "unprognostic (8.94e-2)" "unprognostic (1.13e-2)" 1.9 1.6 0.8 2.2 1.6 5.6 2.8 1.9 2.2 2.0 0.3 1.6 1.3 2.4 2.2 1.9 1.6 1.8 1.3 1.0 0.9 1.8 1.5 1.7 3.3 1.0 0.8 2.9 1.1 1.5 0.8 1.9 1.2 1.6 1.8 2.8 1.4 1.9 1.6 2.6 1.2 1.9 0.7 2.3 1.4 7.6 1.1 4.1 1.5 2.3 2.6 1.5 1.5 1.2 8.2 7.0 8.1 7.5 6.4 3.5 6.5 10.3 4.1 8.1 10.1 11.3 6.2 10.6 5.8 2.6 4.5 10.6 9.5 4.4 11.0 7.6 5.4 5.1 7.8 6.4 1.1 13.0 6.1 2.2 1.6 8.1 5.1 1.8 7.1 6.6 9.1 8.9 6.9 8.1 9.5 9.2 3.2 6.3 11.6 9.0 12.7 4.5 3.4 5.8 7.3 1.9 9.4 7.6 4.0 5.1 8.0 6.0 5.6 11.8 11.0 10.6 8.1 4.4 8.7 10.3 2.3 7.9 7.0 6.6 0.7 2.5 2.0 2.0 1.1 4.3 1.3 0.7 0.6 2.0 2.0 1.7 1.0 1.1 0.9 1.7 1.0 0.6 0.8 1.6 1.9 2.2 1.0 0.9 1.0 0.8 1.2 0.7 1.1 1.2 6.5 0.0 3.1 9.8 8.3 2.7 1.1 1.9 4.6 6.3 3.9 2.4 8.3 1.5 3.1 1.8 2.1 7.6 5.6 1.7 0.0 2.2 65.5 3.5 5.8 5.1 0.0 12.8 21.0 2.7 3.5 4.6 5.1 3.0 1.3 9.4 5.7 1.7 3.5 3.3 15.6 1.6 4.1 3.8 2.9 206.1 9.0 4.0 3.6 18.7 5.9 4.8 3.1 20.1 22.7 2.4 0.8 5.3 8.4 0.8 1.5 1.9 1.1 6.9 6.6 4.7 6.0 26.5 14.0 4.4 1.8 2.3 5.6 9.5 3.2 0.7 FGA ENSG00000171560 "Fibrinogen alpha chain" P02671 4 154583128-154590745 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 388 "liver: 18396.9" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 17365.8" "Cancer enriched" "Detected in many" 43 "liver cancer: 2431.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 429.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016776, HPA051370, HPA064755" Supported Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 407000000 140000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB016776: , HPA051370: AB_2681458, HPA064755: AB_2685345" "unprognostic (5.95e-2)" "unprognostic (6.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.29e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.23e-6)" "unprognostic (4.20e-1)" "unprognostic (1.41e-1)" 2.1 1.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.5 0.0 0.6 0.6 0.7 0.9 13.2 1.2 0.0 0.0 18.8 18396.9 5.3 0.1 0.0 0.0 0.7 18.8 0.0 0.5 0.9 0.0 0.4 0.0 0.0 0.5 0.0 0.5 0.6 0.9 0.0 0.0 9.9 47.4 3.7 0.0 0.1 0.4 0.0 0.1 0.6 0.7 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 0.0 2.7 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.4 0.1 429.3 0.0 6.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.5 6.1 0.0 0.0 0.5 0.2 0.1 3.5 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 1.0 0.0 1.9 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 414.6 3.2 0.0 0.0 0.0 0.0 0.0 1.9 38.6 28.3 0.1 0.2 8.1 0.0 205.9 0.0 1.8 0.1 0.1 1.1 1.3 0.0 0.0 238.8 17365.8 0.1 0.0 0.0 0.0 0.0 328.3 0.0 46.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 1.2 0.0 0.0 0.0 2.3 9.5 0.0 0.0 0.0 0.1 17.4 0.7 0.0 0.0 0.1 17.6 0.0 0.0 0.0 FGB ENSG00000171564 "Fibrinogen beta chain" P02675 4 154563011-154572807 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 373 "liver: 17944.9" "Cell type enriched" "Detected in some" 40 "Hepatocytes: 17273.6" "Cancer enriched" "Detected in many" 42 "liver cancer: 2262.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "Hep G2: 249.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001900, HPA001901, CAB008624" Enhanced Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 110000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB008624: AB_1615610, HPA001900: AB_1078865, HPA001901: AB_1078864" "unprognostic (1.16e-1)" "unprognostic (3.89e-2)" "unprognostic (4.65e-2)" "unprognostic (3.44e-1)" "unprognostic (2.20e-3)" "unprognostic (1.42e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.72e-5)" "unprognostic (2.48e-2)" "unprognostic (7.91e-2)" 2.0 0.8 0.0 0.0 0.0 0.1 2.8 0.0 0.0 1.3 0.0 0.5 0.0 0.6 0.3 0.6 0.8 0.4 1.4 0.0 0.0 48.0 17944.9 0.5 0.1 0.0 0.0 0.6 3.3 0.0 0.5 1.0 0.0 0.4 0.0 0.0 0.4 0.0 0.5 0.5 1.2 0.0 0.0 12.1 6.8 0.5 0.0 0.3 0.4 0.0 0.1 0.5 0.7 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 2.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.2 0.1 249.9 0.0 5.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.8 0.0 0.9 0.0 2.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 39.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.6 251.6 0.0 3.7 0.0 0.0 0.0 0.0 1.9 10.6 0.5 0.6 0.8 13.1 1.8 302.1 0.0 3.8 0.2 0.0 0.0 5.9 0.0 0.0 318.1 17273.6 0.3 0.0 0.0 0.0 0.0 421.7 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.7 0.0 0.0 0.0 FGG ENSG00000171557 "Fibrinogen gamma chain" P02679 4 154604134-154612967 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 330 "liver: 16556.3" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 10221.7" "Cancer enriched" "Detected in many" 19 "liver cancer: 1503.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "Hep G2: 735.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027529, CAB033120, HPA074638" Supported Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 267000000000 73000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB033120: AB_2103818, HPA027529: AB_10601322, HPA074638: " "unprognostic (1.26e-2)" "unprognostic (4.77e-3)" "unprognostic (6.33e-3)" "unprognostic (3.69e-3)" "unprognostic (2.18e-3)" "unprognostic (9.63e-2)" "unprognostic (7.57e-3)" "prognostic unfavorable (1.00e-6)" "unprognostic (1.75e-3)" "unprognostic (3.21e-1)" "unprognostic (1.14e-1)" 1.7 34.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.3 0.0 0.4 0.0 0.4 0.2 0.6 0.7 25.0 1.2 0.0 0.0 8.8 16556.3 50.2 0.1 0.0 0.0 1.4 15.8 0.0 0.4 6.3 0.0 0.4 0.0 0.0 0.4 0.3 0.4 0.5 0.6 0.0 0.0 9.1 8.7 3.0 0.1 0.3 0.4 0.0 0.0 0.5 0.6 0.1 0.0 13.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.2 0.0 1.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.5 0.4 735.3 0.2 8.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.3 0.0 0.6 0.0 0.0 0.3 6.4 0.0 0.0 0.6 0.0 0.0 5.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.5 0.1 0.1 1.7 0.0 3.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 19.2 214.4 0.0 31.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 633.4 2.5 0.0 0.0 0.0 0.0 0.1 0.0 21.9 4.3 0.0 0.1 9.2 0.0 157.7 0.0 48.5 0.2 0.5 0.0 0.1 11.4 1.1 202.4 10221.7 0.2 0.0 0.0 0.0 0.0 289.5 0.0 0.5 0.0 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 161.8 0.0 0.0 0.0 0.0 0.0 1.6 1.5 0.0 0.0 0.0 0.1 2.0 0.6 0.0 0.0 0.4 17.3 0.2 0.0 0.0 FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 65.7;Endothelial cells: 84.2;Hepatic stellate cells: 64.6;Kupffer cells: 86.4;Microglial cells: 231.4;monocytes: 68.4;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 113.9;HUVEC TERT2: 60.5;REH: 49.8;TIME: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" 10.2 1.9 3.7 10.9 2.3 12.2 6.0 2.1 2.8 5.7 1.2 3.7 3.2 4.6 1.1 2.8 2.7 6.1 6.2 1.8 2.9 2.1 2.8 10.8 12.3 4.7 2.7 1.2 1.7 3.5 0.7 12.5 4.3 1.9 2.9 0.5 2.2 2.2 2.8 1.7 4.0 5.9 3.5 35.8 4.3 0.9 3.9 17.2 2.9 6.6 10.4 6.7 1.9 2.8 0.2 0.0 5.6 0.0 0.8 1.0 0.1 3.3 9.2 3.8 3.1 0.0 0.0 18.5 31.7 11.1 1.1 0.1 0.8 13.5 4.1 9.0 0.2 113.9 0.5 0.0 6.0 13.7 14.6 0.8 1.1 7.7 17.3 11.1 60.5 25.6 0.0 23.3 0.8 0.0 13.3 8.1 1.8 0.0 3.1 49.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 20.4 63.0 0.7 0.0 0.2 3.5 7.3 16.4 16.6 0.1 31.8 5.2 34.5 15.5 24.5 10.1 15.3 11.9 6.8 8.9 8.2 19.1 6.0 3.7 8.2 11.8 12.3 19.1 3.3 11.1 20.1 3.7 2.3 2.1 2.8 1.8 2.9 4.7 2.7 4.3 3.5 3.9 2.8 53.4 6.4 5.3 0.3 65.7 5.1 0.3 1.7 2.2 0.0 0.7 1.3 5.5 5.7 0.1 1.8 0.0 0.4 43.1 0.0 0.0 0.0 0.5 0.4 0.6 84.2 0.0 23.4 0.3 0.0 0.4 5.9 2.0 0.3 22.8 0.0 64.6 1.3 43.2 0.0 1.5 0.1 0.0 86.4 24.7 0.5 1.8 60.3 7.2 231.4 68.4 0.1 93.7 4.0 0.7 0.0 0.0 0.7 56.9 0.3 0.0 0.4 0.8 0.4 6.6 2.1 3.1 0.2 0.1 0.6 4.1 0.3 52.8 0.9 0.2 0.4 FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 1203.7;intestine: 1462.2" "Cell type enhanced" "Detected in many" "Peritubular cells: 500.6;Sertoli cells: 420.7;Smooth muscle cells: 459.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Enhanced "Plasma membrane,Actin filaments,Cytosol" NA NA 730000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: AB_2797215, HPA001016: , HPA001115: AB_1078871, HPA002925: AB_1078869" "unprognostic (1.39e-1)" "unprognostic (9.40e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (6.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.23e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.49e-3)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.88e-4)" 267.4 55.9 14.4 223.2 18.5 157.9 164.2 15.2 43.0 392.1 54.7 1462.2 89.9 1203.7 35.5 454.7 609.4 137.9 108.4 14.8 23.0 70.5 21.2 238.9 65.0 39.9 19.9 236.7 50.5 13.4 30.5 79.2 24.4 369.2 86.9 9.0 80.3 617.2 49.7 124.7 354.6 706.6 21.1 102.7 508.0 33.7 34.0 48.1 85.6 31.2 38.1 1053.9 286.4 21.5 947.2 719.2 246.7 316.1 209.8 278.4 400.9 614.0 680.1 552.5 489.8 469.2 169.4 80.5 1551.4 966.4 970.1 528.3 224.0 538.1 152.7 333.6 77.8 262.2 914.9 159.7 375.9 309.3 324.9 266.1 126.1 825.5 327.0 533.8 417.1 94.9 74.7 538.7 401.3 210.7 148.5 93.1 258.3 97.9 470.9 147.8 221.2 71.6 197.2 193.4 52.9 119.7 515.8 80.2 381.1 187.3 79.1 96.3 1016.6 625.2 586.8 640.0 1147.1 333.7 212.8 162.3 580.3 202.4 638.7 7.6 24.9 11.8 32.6 23.1 21.2 10.2 15.6 29.2 22.4 4.6 6.0 14.3 3.6 10.5 34.2 2.7 20.7 56.2 14.4 18.5 15.2 43.0 14.8 23.0 39.9 19.9 24.4 21.1 34.0 21.5 105.1 57.7 38.7 30.0 76.9 124.3 85.9 127.8 85.4 3.5 40.9 153.5 34.5 38.6 26.1 35.0 0.0 24.6 257.7 2.6 1.9 272.0 2.1 33.8 186.3 107.0 1.8 39.7 11.8 133.1 90.9 137.9 13.3 55.8 26.0 334.5 81.8 4.3 120.3 11.8 8.6 2.5 22.4 141.0 263.0 13.7 122.4 227.7 88.9 30.9 207.9 39.4 270.8 8.0 2.6 347.4 1.5 500.6 98.7 96.1 1.9 3.0 9.1 4.3 420.7 118.3 459.3 4.1 8.9 48.8 73.6 20.0 172.3 134.7 3.3 35.3 FYB1 "ADAP, FYB, FYB-120/130, SLAP-130" ENSG00000082074 "FYN binding protein 1" O15117 5 39105252-39274528 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 53.0;lymphoid tissue: 112.8" "Cell type enhanced" "Detected in many" "dendritic cells: 142.9;Extravillous trophoblasts: 88.7;Hofbauer cells: 157.0;Macrophages: 104.2;T-cells: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1670.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HEL: 61.5;JURKAT: 211.9;MOLT-4: 212.9;REH: 61.3;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025336, HPA026796, HPA067427" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 6200000 "Cluster 1: Neutrophils - Mixed function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Nucleoplasm "CAB025336: , HPA026796: AB_10964126, HPA067427: " "unprognostic (5.65e-2)" "unprognostic (2.92e-2)" "unprognostic (1.56e-2)" "unprognostic (6.26e-2)" "unprognostic (4.08e-1)" "unprognostic (3.29e-2)" "unprognostic (2.60e-1)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "unprognostic (5.63e-2)" "unprognostic (5.35e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (2.40e-1)" "unprognostic (4.14e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-1)" 10.2 5.8 5.7 82.5 5.5 53.0 5.1 6.3 9.3 6.6 7.4 10.0 9.1 3.8 10.5 5.7 3.6 16.8 2.4 5.4 7.9 5.0 13.6 17.6 85.8 16.7 19.1 2.7 1.8 2.1 1.5 17.9 15.8 4.2 11.0 0.5 7.4 3.0 1.2 2.0 15.0 11.6 9.3 73.0 12.2 3.3 13.3 112.8 2.6 2.7 63.0 17.1 1.8 13.9 0.2 4.2 0.0 0.0 0.5 0.0 21.1 0.1 1.2 0.3 0.4 0.4 0.3 0.3 0.0 0.0 8.0 16.4 0.0 0.3 0.1 0.3 0.0 61.5 0.0 0.1 0.0 23.3 18.6 0.3 0.4 0.0 0.4 0.1 0.0 211.9 0.0 0.0 0.0 0.0 212.9 13.5 0.2 0.1 0.1 61.3 0.0 0.3 1.0 3.5 0.1 0.0 0.1 0.5 6.5 1.4 0.0 5.2 0.0 0.0 0.2 0.2 0.2 0.4 0.0 4.5 0.0 81.4 0.2 151.3 359.0 354.6 76.3 406.5 52.9 1.8 216.7 134.5 127.6 1.3 271.7 169.8 1670.8 89.9 483.9 30.8 231.5 400.1 5.7 5.5 6.3 9.3 5.4 7.9 16.7 19.1 15.8 9.3 13.3 13.9 4.4 16.0 24.7 0.0 6.2 0.0 0.0 0.0 0.0 0.0 3.2 7.6 0.0 0.0 5.6 14.7 0.0 28.8 142.9 0.0 9.8 0.4 0.0 0.7 1.1 4.3 0.0 0.0 0.0 0.0 88.7 3.8 0.0 1.0 15.2 0.1 0.0 0.0 157.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.2 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 35.9 3.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 40.2 119.3 0.1 0.0 0.0 G6PD G6PD1 ENSG00000160211 "Glucose-6-phosphate dehydrogenase" P11413 X 154531391-154547572 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 105.9" "Cell type enhanced" "Detected in many" "monocytes: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 412.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 412.7" "Cell line enhanced" "Detected in all" "A549: 2333.8;MCF7: 883.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000247, HPA000834" Enhanced Enhanced "Centriolar satellite,Cytosol" No No 2400000 "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Centriolar satellite" "HPA000247: AB_1078978, HPA000834: AB_1078977" "unprognostic (1.73e-2)" "unprognostic (1.53e-3)" "unprognostic (1.13e-2)" "unprognostic (1.02e-1)" "unprognostic (7.78e-2)" "unprognostic (4.34e-2)" "prognostic unfavorable (9.45e-13)" "unprognostic (2.78e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-2)" "unprognostic (1.09e-1)" "unprognostic (3.66e-1)" "unprognostic (2.89e-3)" "unprognostic (2.83e-1)" "unprognostic (1.94e-1)" "unprognostic (1.47e-1)" "unprognostic (7.25e-2)" 40.7 39.1 19.9 30.2 21.8 105.9 31.9 20.5 28.3 20.6 20.0 13.9 13.1 21.6 13.3 54.3 19.3 46.5 14.3 21.3 22.7 12.7 6.5 29.4 28.9 25.4 22.2 24.1 13.0 9.6 27.5 13.7 24.5 12.2 13.1 26.1 21.2 14.4 4.2 21.3 12.4 25.6 19.7 26.9 18.1 54.0 26.1 26.2 45.9 5.1 37.2 33.8 22.4 21.9 168.5 2333.8 49.7 189.7 207.2 281.7 43.5 116.0 341.7 120.0 205.8 111.2 61.9 110.9 174.1 274.3 475.9 146.3 79.3 202.5 60.3 111.4 55.0 116.8 517.2 244.6 401.6 117.8 373.5 136.6 58.5 233.9 49.8 185.6 252.5 79.8 69.6 46.3 218.4 883.9 77.5 93.0 35.3 549.5 172.2 74.9 28.4 120.5 357.1 210.9 49.6 62.0 115.9 444.5 99.9 65.0 67.1 99.4 289.8 73.1 250.0 102.5 181.8 58.2 80.0 189.8 200.6 77.5 150.9 166.1 84.9 412.7 50.3 72.1 32.1 16.0 13.7 36.7 40.1 17.0 16.5 28.2 137.4 69.3 63.5 18.9 18.7 72.8 19.9 21.8 20.5 28.3 21.3 22.7 25.4 22.2 24.5 19.7 26.1 21.9 7.9 0.0 17.0 4.6 21.5 12.5 24.3 46.6 8.6 6.2 14.6 8.6 1.1 14.3 22.9 11.0 18.8 29.6 58.9 25.5 29.4 39.3 10.3 7.7 13.7 13.2 9.5 37.7 2.9 29.3 41.2 19.6 23.4 10.7 37.5 26.1 18.2 1.6 45.6 33.7 2.3 11.5 24.4 58.2 26.0 20.8 26.1 56.6 19.6 5.6 112.3 13.6 83.4 3.5 3.7 31.0 11.4 16.1 21.6 23.9 18.5 18.3 10.9 32.5 6.6 7.5 23.6 10.9 32.8 34.4 13.8 36.3 33.8 11.6 13.5 30.5 GATA1 "ERYF1, GATA-1, GF1, NF-E1, NFE1" ENSG00000102145 "GATA binding protein 1" P15976 X 48786562-48794311 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "bone marrow: 59.9" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 165.6" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "eosinophil: 471.7" "Lineage enriched" "Detected in single" 1877 "granulocytes: 471.7" "Group enriched" "Detected in some" 9 "HEL: 221.5;HMC-1: 211.9;K-562: 238.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA000232, HPA000233, CAB009195" Enhanced Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB009195: AB_2232148, HPA000232: AB_1078949, HPA000233: AB_1078951" "unprognostic (1.93e-1)" "unprognostic (7.54e-2)" "unprognostic (8.95e-3)" "unprognostic (3.84e-3)" "unprognostic (2.25e-1)" "unprognostic (3.00e-4)" "unprognostic (4.87e-2)" "unprognostic (3.48e-2)" "unprognostic (4.44e-2)" "unprognostic (1.95e-2)" "unprognostic (6.04e-2)" "unprognostic (7.71e-3)" "unprognostic (4.13e-2)" "unprognostic (2.24e-1)" "unprognostic (2.78e-1)" "unprognostic (9.10e-2)" "unprognostic (2.71e-2)" 0.2 0.1 0.0 0.1 0.2 59.9 0.1 0.2 0.1 0.2 0.0 0.2 0.5 0.3 0.0 0.2 0.1 0.6 0.1 0.0 0.2 0.2 0.3 2.0 0.1 0.3 0.2 0.0 0.0 0.0 0.2 1.0 0.2 0.3 0.3 0.4 0.1 0.1 0.0 0.3 0.5 0.3 0.2 2.0 0.5 1.4 0.2 0.1 0.1 0.4 0.0 0.4 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 221.5 0.0 0.0 0.0 0.2 211.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 238.9 0.4 0.0 0.0 0.1 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 83.6 0.2 471.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.2 0.0 0.0 4.4 0.0 0.2 0.2 0.1 0.0 0.2 0.3 0.2 0.2 0.2 0.2 0.6 0.0 0.0 1.3 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 165.6 0.1 0.0 0.5 0.3 0.0 0.0 37.9 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.4 31.5 0.0 9.2 0.0 0.0 0.1 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.1 1.2 0.2 0.0 0.0 GATA2 NFE1B ENSG00000179348 "GATA binding protein 2" P23769 3 128479427-128493201 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Phagocytosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 261.6;Glandular and luminal cells: 116.5;granulocytes: 638.7;Syncytiotrophoblasts: 321.4" "Group enriched" "Detected in all" 5 "endometrial cancer: 12.7;prostate cancer: 36.7;urothelial cancer: 13.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 330 "basophil: 513.2" "Lineage enriched" "Detected in single" 4344 "granulocytes: 513.2" "Cell line enhanced" "Detected in many" "BEWO: 281.0;HEL: 360.7;HMC-1: 187.4;SH-SY5Y: 325.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005633, CAB024847" Enhanced Supported Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "CAB024847: , HPA005633: AB_1078954" "unprognostic (1.71e-1)" "unprognostic (8.90e-2)" "unprognostic (1.12e-1)" "unprognostic (8.61e-2)" "unprognostic (8.67e-2)" "unprognostic (4.17e-2)" "unprognostic (5.96e-3)" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.12e-2)" "unprognostic (3.58e-2)" "unprognostic (3.04e-1)" "prognostic favorable (2.04e-4)" "unprognostic (2.50e-1)" "unprognostic (8.07e-2)" "unprognostic (2.08e-1)" "prognostic favorable (5.22e-5)" 16.9 9.8 7.1 2.7 5.3 5.1 12.8 3.6 4.6 32.9 2.1 6.6 4.3 42.7 7.1 4.9 49.7 10.7 19.5 3.9 3.4 20.7 1.3 34.8 2.8 8.2 12.2 4.3 13.7 6.9 9.7 22.5 7.9 54.4 2.9 0.1 4.8 52.2 6.4 9.2 8.5 10.8 4.0 11.4 6.6 2.7 8.8 0.8 7.3 5.2 1.2 33.8 23.9 4.1 24.4 5.9 1.3 15.9 2.0 0.6 281.0 53.8 45.2 18.0 6.5 10.0 10.7 0.5 14.8 31.9 1.5 25.5 14.7 0.0 7.6 0.0 8.3 360.7 42.9 16.0 4.0 36.8 187.4 0.3 0.3 0.7 0.3 2.9 28.6 0.2 96.7 0.5 0.4 9.0 0.1 74.2 1.0 0.2 1.8 0.1 7.0 0.4 0.5 21.5 21.8 325.9 13.6 70.1 2.4 14.4 13.5 15.0 52.0 1.2 0.7 12.7 7.4 0.1 0.0 0.2 0.6 2.5 3.7 513.2 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.9 7.1 5.3 3.6 4.6 3.9 3.4 8.2 12.2 7.9 4.0 8.8 4.1 69.0 6.4 27.7 0.0 0.9 4.8 25.5 0.0 1.2 0.2 1.5 1.5 5.7 0.0 1.8 75.4 0.0 63.4 2.3 0.5 1.9 0.2 10.1 74.2 43.2 75.4 3.0 62.4 0.0 14.2 261.6 8.8 0.5 116.5 638.7 0.9 57.5 0.2 10.8 0.0 0.0 0.3 0.0 0.3 4.6 6.4 0.6 7.9 8.8 15.9 0.7 0.1 0.0 0.0 0.0 0.9 0.0 0.4 5.4 29.5 0.0 0.2 0.7 0.2 0.0 2.2 11.0 0.6 4.7 0.9 2.4 321.4 14.0 0.2 0.3 10.5 GCLC "GCS, GLCL, GLCLC" ENSG00000001084 "Glutamate-cysteine ligase catalytic subunit" P48506 6 53497341-53616970 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 152.1" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 220.7;Urothelial cells: 144.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 205.4;Hep G2: 178.2;OE19: 287.5;RT4: 189.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009569, HPA036359, HPA036360" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 5800000 "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nucleoli, Cytosol" "CAB009569: AB_675582, HPA036359: AB_10672243, HPA036360: AB_10669789" "unprognostic (8.41e-2)" "unprognostic (1.27e-2)" "unprognostic (5.65e-2)" "unprognostic (2.42e-1)" "unprognostic (1.58e-1)" "unprognostic (2.76e-1)" "unprognostic (2.60e-1)" "unprognostic (7.50e-2)" "unprognostic (9.94e-3)" "unprognostic (4.67e-3)" "unprognostic (1.30e-1)" "unprognostic (5.23e-2)" "prognostic favorable (3.83e-6)" "unprognostic (3.78e-2)" "unprognostic (8.91e-2)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.30e-2)" 26.7 18.3 18.5 16.6 24.9 37.8 27.2 18.1 23.3 9.5 14.1 22.8 41.9 19.2 10.8 37.0 62.9 32.1 16.4 16.8 18.9 34.1 152.1 10.9 26.2 18.4 19.7 8.5 15.9 18.3 4.8 9.1 20.4 26.9 26.0 14.4 13.1 15.8 11.4 18.8 32.2 16.0 18.2 39.1 32.9 11.3 22.5 13.7 30.0 14.5 24.0 63.7 14.5 36.0 31.3 205.4 16.5 39.1 19.4 8.6 22.1 15.5 24.9 11.4 13.3 30.5 70.7 59.1 28.7 14.1 86.9 43.3 50.7 112.5 15.3 46.9 31.4 39.6 38.3 178.2 22.1 52.8 23.5 13.5 46.6 12.8 56.8 15.0 17.7 50.9 22.4 18.2 5.6 32.9 45.5 20.9 30.6 287.5 19.2 14.9 10.2 52.1 37.0 189.8 47.5 23.3 25.9 40.9 27.8 23.8 28.2 24.6 24.6 10.2 35.5 26.0 23.4 24.1 39.9 34.0 25.6 37.0 17.5 1.2 0.5 0.3 0.5 0.9 0.4 0.8 0.5 1.1 2.3 0.5 0.3 0.6 0.2 4.2 1.0 1.6 0.9 0.3 18.5 24.9 18.1 23.3 16.8 18.9 18.4 19.7 20.4 18.2 22.5 36.0 17.1 0.0 2.4 36.9 12.7 34.8 61.6 56.6 47.3 14.4 23.7 13.6 20.9 38.6 47.4 0.0 25.0 6.4 22.9 22.1 11.7 14.6 2.2 34.8 14.9 14.1 220.7 113.2 22.4 12.8 8.6 13.6 43.8 69.8 2.5 50.9 10.4 118.5 22.7 8.4 30.4 19.4 40.7 87.2 10.9 1.5 6.5 32.1 8.8 24.4 10.6 12.5 17.5 30.2 84.1 15.9 13.2 9.4 10.4 88.3 18.2 27.1 66.5 5.0 13.1 14.0 13.5 3.1 9.2 72.6 24.9 7.8 14.9 26.6 14.8 144.8 GCNT2 "bA360O19.2, bA421M1.1, CCAT, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3" ENSG00000111846 "Glucosaminyl (N-acetyl) transferase 2 (I blood group)" Q8N0V5 6 10492223-10629368 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 13.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Endometrial ciliated cells: 79.1;Glandular and luminal cells: 105.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 1.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 44.2;Hep G2: 19.7;SK-MEL-30: 17.1;SuSa: 21.4" "Region enriched" "Detected in all" 4 "basal ganglia: 61.1" "Low region specificity" "Detected in all" HPA026776 Approved Approved "Golgi apparatus" No No 750000 "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA026776: AB_1849573" "unprognostic (2.47e-1)" "unprognostic (6.87e-3)" "unprognostic (3.12e-1)" "unprognostic (1.42e-2)" "unprognostic (9.31e-2)" "unprognostic (2.51e-1)" "unprognostic (4.11e-2)" "unprognostic (2.39e-1)" "unprognostic (1.27e-1)" "unprognostic (2.11e-2)" "unprognostic (6.28e-4)" "unprognostic (3.96e-2)" "unprognostic (1.58e-3)" "unprognostic (6.54e-2)" "unprognostic (6.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" 0.6 0.3 0.7 1.0 0.6 0.3 10.1 2.5 1.1 4.2 4.5 3.6 5.2 1.4 0.2 1.4 0.8 1.5 6.6 0.8 1.1 5.7 5.1 3.9 1.8 1.2 1.0 0.3 1.3 0.4 1.4 2.6 1.4 13.5 2.0 0.3 4.2 0.3 0.7 1.4 5.8 1.6 0.9 1.5 5.9 2.5 0.9 0.5 1.2 1.8 2.4 1.0 0.7 1.0 6.3 4.9 1.5 4.8 0.0 0.0 9.6 0.0 4.1 1.1 0.5 11.0 5.2 3.5 44.2 0.0 3.2 0.3 0.4 5.1 2.9 3.1 1.8 0.5 2.6 19.7 0.0 1.7 4.7 0.0 0.0 0.5 0.0 2.4 9.1 0.0 0.4 0.0 0.4 0.0 0.0 4.0 4.4 0.0 3.6 0.2 3.8 6.0 16.0 2.9 4.0 1.2 0.0 14.4 17.1 21.4 0.3 0.8 6.4 0.8 0.5 0.0 5.0 0.1 0.0 2.4 0.8 0.3 2.3 1.9 1.1 0.5 0.1 0.8 0.0 0.7 0.1 0.1 0.8 0.4 0.1 0.2 0.1 0.2 0.2 0.2 0.0 0.3 0.7 0.6 2.5 1.1 0.8 1.1 1.2 1.0 1.4 0.9 0.9 1.0 1.4 76.9 32.4 1.0 9.5 4.6 6.6 15.5 9.6 5.1 30.5 16.1 18.4 2.8 28.6 7.3 0.0 27.9 6.4 15.5 11.7 2.9 4.3 79.1 5.5 11.0 2.4 25.9 0.7 24.7 2.1 2.0 16.8 105.5 2.5 0.0 12.8 32.0 15.8 3.3 11.8 5.6 6.1 7.7 9.4 8.2 0.3 7.8 49.8 52.5 11.1 2.4 0.0 18.6 1.1 12.0 11.9 0.0 1.0 16.6 44.3 13.4 27.9 0.6 0.0 0.7 2.2 6.2 27.6 11.2 1.7 10.9 3.1 0.0 16.3 8.1 GFI1B ZNF163B ENSG00000165702 "Growth factor independent 1B transcriptional repressor" Q5VTD9 9 132944000-132991687 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "bone marrow: 39.0" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 99.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 20 "basophil: 195.6;eosinophil: 395.8" "Lineage enriched" "Detected in many" 26 "granulocytes: 395.8" "Group enriched" "Detected in some" 5 "HEL: 168.9;HMC-1: 104.6;K-562: 53.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004420, HPA006291" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "CAB004420: AB_2110132, HPA006291: " "unprognostic (1.79e-2)" "unprognostic (2.90e-4)" "unprognostic (6.54e-2)" "unprognostic (1.76e-1)" "unprognostic (2.33e-1)" "unprognostic (1.54e-2)" "unprognostic (2.53e-3)" "unprognostic (1.05e-1)" "unprognostic (2.47e-1)" "unprognostic (1.54e-1)" "unprognostic (4.61e-2)" "unprognostic (3.71e-2)" "unprognostic (2.17e-1)" "unprognostic (2.53e-1)" "unprognostic (1.53e-2)" "unprognostic (1.41e-1)" 0.0 0.0 0.0 0.3 0.1 39.0 0.0 0.2 0.2 0.0 0.2 0.5 0.9 0.0 0.1 0.1 0.0 0.3 0.2 0.1 0.0 0.0 0.2 1.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.0 0.1 0.1 0.4 0.5 1.0 0.1 0.1 1.8 0.3 2.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 1.9 0.3 23.8 0.0 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 168.9 0.2 0.1 0.0 0.1 104.6 0.0 1.4 0.0 0.2 0.0 0.0 0.0 53.0 0.2 0.0 0.0 0.1 17.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 1.5 0.0 0.0 0.0 195.6 0.3 395.8 0.1 1.9 0.1 0.1 0.1 0.0 1.9 0.2 0.5 0.1 3.9 0.5 15.1 1.0 0.0 12.5 0.0 0.1 0.2 0.2 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.4 0.2 0.0 0.6 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.2 0.0 1.3 0.0 1.8 0.0 0.0 0.1 0.1 0.8 0.0 0.1 3.8 0.0 0.3 0.4 1.2 99.1 0.4 0.0 0.2 0.3 0.0 0.1 14.5 0.4 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.3 0.0 12.9 0.0 15.8 0.0 0.0 0.6 0.0 0.0 0.5 0.2 0.0 24.2 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.3 0.2 1.0 0.6 0.1 GGCX VKCFD1 ENSG00000115486 "Gamma-glutamyl carboxylase" P38435 2 85544720-85561547 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 118.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018284 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA018284: AB_1849641" "unprognostic (4.88e-3)" "unprognostic (1.13e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (1.82e-6)" "unprognostic (5.67e-2)" "unprognostic (1.85e-3)" "unprognostic (2.96e-2)" "unprognostic (3.77e-2)" "unprognostic (5.64e-2)" "unprognostic (2.18e-2)" "unprognostic (6.45e-3)" "unprognostic (5.23e-2)" "unprognostic (8.17e-3)" "unprognostic (7.85e-2)" "unprognostic (2.59e-1)" "unprognostic (7.63e-3)" "unprognostic (9.38e-2)" 13.8 11.0 6.0 8.3 7.4 3.2 10.8 8.3 7.7 10.7 11.7 7.8 7.4 10.5 13.8 9.2 10.5 11.3 9.5 6.9 6.2 16.3 118.8 13.8 6.3 7.4 6.9 12.4 15.8 18.0 7.8 23.4 7.5 10.0 9.9 7.7 14.7 12.1 7.9 9.2 7.3 13.4 7.3 6.2 9.1 4.7 7.0 4.8 12.6 8.6 7.2 12.2 8.8 11.2 17.1 27.2 19.0 21.3 93.8 26.6 42.2 29.9 35.1 21.6 30.4 47.3 20.6 6.1 29.7 49.3 27.1 27.2 13.7 37.7 23.7 10.9 18.7 11.1 17.4 45.2 34.8 7.0 10.1 33.1 22.0 43.8 29.7 35.6 31.0 10.8 13.5 8.7 63.5 22.4 3.5 5.3 8.9 47.7 23.4 6.6 44.6 15.3 30.0 32.5 7.2 12.1 26.8 52.2 28.2 32.1 25.6 6.8 28.6 27.5 23.9 27.1 20.9 6.8 20.1 5.1 26.5 7.1 39.4 3.7 4.2 2.2 1.7 4.4 1.6 0.4 0.7 0.7 2.9 0.4 1.7 1.6 1.7 1.4 2.6 2.4 1.2 2.0 6.0 7.4 8.3 7.7 6.9 6.2 7.4 6.9 7.5 7.3 7.0 11.2 27.1 28.9 40.3 10.1 25.1 18.7 20.6 27.8 13.6 21.6 22.9 19.8 27.9 32.9 24.1 29.5 16.7 60.8 28.4 16.1 7.9 29.9 4.2 16.9 19.4 20.8 14.4 5.7 10.9 39.5 50.2 29.4 11.7 26.8 15.8 17.8 23.9 163.0 31.3 8.4 8.9 17.6 22.4 26.9 29.0 2.2 20.2 24.5 21.4 5.6 29.6 19.5 17.5 9.5 12.6 25.0 12.6 20.3 38.4 16.4 16.2 27.1 16.9 33.6 6.6 42.3 22.8 23.5 11.2 20.0 15.2 53.8 20.8 15.1 16.4 23.6 GLRX5 "C14orf87, GRX5, PR01238" ENSG00000182512 "Glutaredoxin 5" Q86SX6 14 95533503-95544724 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 518.5;Erythroid cells: 1134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042465, HPA063716" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA042465: AB_10794048, HPA063716: AB_2685102" "unprognostic (2.57e-1)" "unprognostic (6.76e-2)" "unprognostic (1.60e-2)" "unprognostic (2.69e-2)" "unprognostic (3.72e-2)" "unprognostic (2.43e-3)" "unprognostic (1.29e-1)" "unprognostic (5.41e-2)" "unprognostic (8.28e-2)" "prognostic favorable (1.08e-5)" "unprognostic (1.85e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.83e-10)" "unprognostic (1.44e-1)" "unprognostic (3.81e-2)" "unprognostic (2.66e-2)" "unprognostic (8.91e-2)" 37.2 52.1 44.1 17.6 44.9 178.8 27.2 43.8 50.2 22.3 46.7 44.8 46.2 19.2 39.0 24.5 23.6 17.5 76.9 46.6 45.8 74.5 105.5 18.3 23.1 43.3 44.5 32.8 31.5 46.3 18.9 37.8 44.3 26.8 37.3 10.1 29.3 29.6 195.0 18.3 33.2 24.4 42.9 20.8 34.2 35.7 46.2 40.3 26.7 168.9 27.0 24.5 15.0 42.9 77.1 92.7 61.4 68.0 74.2 57.5 202.0 54.9 56.1 69.4 69.1 124.8 87.5 111.7 77.4 42.8 39.2 75.5 116.5 79.6 71.5 68.5 94.4 100.3 63.4 202.2 73.5 160.9 96.5 55.4 74.1 49.9 81.1 28.1 76.1 94.4 115.7 88.3 61.2 205.5 133.6 165.9 81.5 89.7 107.8 220.8 184.3 67.8 93.3 89.3 127.9 75.2 54.8 81.3 87.7 59.9 107.7 72.6 55.6 30.5 65.0 77.6 85.7 41.7 57.9 92.0 67.2 99.8 72.2 0.4 2.9 4.8 3.4 4.3 4.9 4.6 4.6 6.0 4.7 5.4 3.7 3.9 1.3 3.9 2.7 9.0 6.2 1.8 44.1 44.9 43.8 50.2 46.6 45.8 43.3 44.5 44.3 42.9 46.2 42.9 78.7 28.9 30.0 7.8 41.1 108.5 58.7 7.5 61.5 38.5 112.8 135.9 150.0 64.3 10.4 95.6 33.3 97.8 66.5 76.3 518.5 15.2 312.0 49.7 61.5 58.9 54.0 1134.9 15.0 15.6 164.9 66.2 46.4 48.3 14.7 110.3 47.2 147.2 58.7 50.5 16.4 72.1 4.1 41.7 58.7 90.2 54.3 50.7 87.2 7.5 21.3 128.1 52.5 12.5 15.2 15.2 39.5 73.7 75.2 108.2 51.8 281.4 9.1 43.0 59.2 61.1 92.7 115.4 79.0 102.2 124.9 53.8 48.8 169.0 88.0 76.6 GP1BA "CD42b, GP1B, GPIbalpha" ENSG00000185245 "Glycoprotein Ib platelet subunit alpha" P07359 17 4932277-4935023 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Bernard Soulier syndrome, Disease variant, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.9;lymphoid tissue: 14.7" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.9;Macrophages: 14.2" "Cancer enhanced" "Detected in many" "testis cancer: 2.8" "Region enriched" "Detected in single" 5 "cerebellum: 2.1" "Immune cell enriched" "Detected in single" 13 "basophil: 7.0" "Lineage enriched" "Detected in single" 43 "granulocytes: 7.0" "Cell line enriched" "Detected in some" 24 "HEL: 71.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002496, HPA013316" Supported NA NA 1600000000 "Cluster 34: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "CAB002496: AB_563748, HPA013316: AB_1855459" "unprognostic (4.87e-4)" "unprognostic (8.21e-2)" "unprognostic (2.81e-2)" "unprognostic (6.11e-3)" "unprognostic (1.50e-2)" "unprognostic (1.59e-3)" "unprognostic (7.30e-3)" "unprognostic (5.58e-2)" "unprognostic (2.19e-1)" "unprognostic (1.64e-1)" "unprognostic (6.54e-4)" "unprognostic (1.27e-1)" "unprognostic (4.85e-3)" "unprognostic (4.58e-3)" "unprognostic (2.56e-1)" "unprognostic (3.53e-4)" "unprognostic (8.35e-2)" 0.5 0.1 0.1 3.8 0.4 4.9 0.4 2.1 0.2 0.4 0.1 0.7 1.2 0.3 0.0 0.5 0.4 0.3 0.5 0.1 0.0 0.5 0.8 1.5 14.7 0.1 0.0 0.4 0.3 0.0 0.2 0.3 0.1 0.4 0.5 2.3 0.9 0.0 2.7 2.4 1.8 0.0 0.0 3.6 0.8 0.4 0.1 0.6 0.4 0.0 7.7 0.4 0.5 0.0 0.1 2.3 0.5 0.3 0.0 0.0 1.1 0.3 0.0 0.0 0.0 2.2 0.3 2.3 0.7 0.0 0.0 2.3 0.0 0.0 0.0 0.8 1.8 71.6 1.2 0.0 0.0 0.4 2.5 0.0 0.0 0.0 0.0 0.7 0.0 1.3 0.7 0.7 0.0 0.8 0.6 0.3 0.3 0.2 0.4 1.2 0.5 0.3 0.0 1.4 0.1 0.3 0.9 0.0 0.3 0.6 2.9 1.3 0.3 0.4 0.4 1.5 0.2 1.2 0.5 1.7 1.0 1.1 0.7 7.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 2.2 0.1 0.4 2.1 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.3 1.5 0.6 0.4 0.0 1.8 0.2 0.5 1.1 0.0 0.2 0.0 2.1 0.3 0.4 0.1 3.9 0.2 0.3 0.8 1.8 0.5 0.0 1.7 0.2 0.0 0.2 0.7 0.0 2.4 0.0 0.1 2.5 0.9 0.1 0.0 0.2 0.0 0.0 0.9 3.3 0.6 0.3 14.2 0.0 0.0 2.6 0.3 1.0 0.0 0.1 0.0 0.0 1.9 0.3 0.4 0.3 0.9 0.0 2.7 0.0 1.4 0.5 1.0 0.6 0.0 1.8 0.3 1.0 0.1 0.1 0.3 GP1BB "CD42c, GPIbbeta" ENSG00000203618 "Glycoprotein Ib platelet subunit beta" P13224 22 19723539-19724771 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Bernard Soulier syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.2;heart muscle: 27.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 74.0;neutrophil: 74.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 74.5" "Cell line enriched" "Detected in some" 4 "K-562: 85.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA 4400000 "Cluster 34: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" 2.7 2.0 39.0 0.2 40.1 2.7 2.5 26.1 51.0 9.2 11.1 2.9 0.0 4.8 0.0 11.2 4.4 0.0 27.1 53.2 18.3 2.9 1.2 4.1 0.2 16.2 15.4 6.3 2.2 2.5 22.1 0.2 15.6 3.4 0.0 0.6 2.4 0.0 1.4 24.4 1.4 0.1 7.9 10.1 2.3 4.2 28.0 0.1 3.1 0.5 0.1 1.6 7.2 22.9 0.0 1.1 1.6 0.7 0.0 0.0 0.2 1.5 0.0 0.1 0.4 0.0 0.1 0.2 0.3 0.0 0.3 0.8 0.1 0.1 0.0 0.0 7.7 4.1 0.1 0.0 0.0 0.0 10.3 0.2 0.1 0.3 0.0 0.0 0.0 0.2 85.4 0.1 0.5 0.1 0.3 19.2 0.4 0.1 2.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.9 1.3 0.2 0.0 2.9 0.1 0.0 0.8 0.0 0.0 0.0 0.2 0.0 74.0 8.5 12.5 1.6 3.1 0.8 0.5 0.5 0.2 3.6 0.9 1.0 0.8 74.5 1.1 0.6 12.6 2.2 417.7 39.0 40.1 26.1 51.0 53.2 18.3 16.2 15.4 15.6 7.9 28.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GP6 GPVI ENSG00000088053 "Glycoprotein VI platelet" Q9HCN6 19 55013705-55038264 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Early spermatids: 14.3;Excitatory neurons: 9.9;Inhibitory neurons: 10.2;Late spermatids: 8.7;Macrophages: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HEL: 9.4;K-562: 4.1;U-2 OS: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047611, HPA066482" Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA 44000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "HPA047611: , HPA066482: AB_2685674" "unprognostic (3.06e-3)" "unprognostic (4.58e-2)" "unprognostic (1.74e-5)" "unprognostic (1.94e-1)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "unprognostic (7.50e-4)" "unprognostic (2.81e-1)" "unprognostic (1.00e-1)" "unprognostic (4.18e-2)" "unprognostic (3.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.53e-1)" "unprognostic (2.62e-1)" "unprognostic (3.32e-2)" "unprognostic (5.44e-3)" "unprognostic (2.70e-2)" 0.1 0.0 0.1 0.0 0.1 0.9 0.2 0.7 0.5 0.5 0.0 0.2 0.0 0.2 0.0 1.4 0.4 0.0 0.7 0.1 0.0 0.5 0.2 0.9 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 0.1 0.4 0.0 0.2 0.4 0.1 0.1 1.2 0.1 0.0 0.0 0.9 0.2 2.7 0.0 0.0 0.4 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.3 9.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 2.5 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.2 0.1 0.1 0.7 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.3 0.3 0.0 2.0 0.3 0.4 0.7 1.5 0.3 0.0 6.2 0.1 0.4 0.7 0.0 0.1 14.3 1.4 0.4 1.2 0.0 0.0 9.9 0.4 0.3 0.6 0.0 2.2 1.3 0.8 3.3 0.2 0.1 3.3 10.2 0.0 0.0 0.8 0.2 8.7 0.3 10.3 0.0 1.0 0.3 0.4 2.1 1.5 1.5 0.2 0.1 0.0 0.0 0.4 0.1 0.0 1.9 2.6 0.0 0.4 0.2 1.4 1.2 0.0 0.1 0.5 0.4 0.0 0.3 0.7 GP9 "CD42a, GPIX" ENSG00000169704 "Glycoprotein IX platelet" P14770 3 129060779-129062406 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Bernard Soulier syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.1;lung: 3.2;lymphoid tissue: 8.9" "Cell type enriched" "Detected in some" 8 "Macrophages: 151.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "basophil: 29.5;neutrophil: 13.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 29.5" "Cell line enriched" "Detected in some" 14 "HEL: 85.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063182 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 2600000 "Cluster 34: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" Nucleoplasm "HPA063182: AB_2684956" "unprognostic (1.70e-1)" "unprognostic (3.97e-1)" "unprognostic (1.10e-1)" "unprognostic (3.80e-2)" "unprognostic (2.50e-2)" "unprognostic (3.24e-1)" "unprognostic (2.53e-2)" "unprognostic (8.47e-2)" "unprognostic (8.70e-2)" 0.1 0.0 0.0 0.0 0.0 5.1 0.1 0.0 0.3 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.1 1.8 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 1.2 0.2 0.2 0.7 0.3 0.0 0.0 0.3 0.6 0.1 0.1 0.0 13.9 0.0 0.2 3.0 0.0 51.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.0 0.0 14.4 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 2.9 0.1 1.7 0.0 0.0 0.6 0.0 1.3 0.0 18.3 0.0 151.9 0.0 0.0 4.1 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.7 0.3 0.0 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 331.0;Late spermatids: 1127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" No No 86000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB018655: AB_2112653, CAB040563: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" 196.9 283.2 83.4 74.5 101.9 222.8 129.0 67.7 130.5 95.0 84.8 162.9 113.7 92.4 27.2 197.8 88.8 87.1 407.2 108.5 73.6 196.8 222.6 91.2 66.4 73.5 58.5 97.0 84.2 166.3 147.2 47.5 69.3 94.4 84.3 156.1 105.1 61.0 416.6 120.1 126.5 78.4 34.0 102.2 122.5 95.9 83.2 50.1 100.8 374.6 76.0 147.9 121.5 95.8 572.9 596.1 58.7 433.3 167.5 121.9 134.1 183.4 132.4 206.3 253.7 314.9 169.6 303.5 311.4 177.9 149.1 343.7 337.7 437.0 259.4 461.0 105.1 382.1 252.3 310.8 108.4 517.6 259.3 173.7 136.6 289.0 132.7 273.3 209.3 230.5 210.3 261.8 140.2 319.2 245.5 133.5 158.0 421.3 174.6 242.7 149.1 649.4 254.1 275.4 304.9 185.8 331.9 634.3 131.7 100.5 144.4 161.7 171.9 80.8 185.5 256.7 312.8 535.5 383.7 318.4 287.4 372.3 170.6 188.8 93.2 331.3 80.4 141.2 99.1 59.9 73.7 93.1 101.0 50.5 61.8 72.8 7.4 58.0 180.3 31.6 83.4 123.4 83.4 101.9 67.7 130.5 108.5 73.6 73.5 58.5 69.3 34.0 83.2 95.8 34.2 28.9 40.0 98.9 43.8 25.9 30.1 104.5 42.7 98.8 34.1 27.2 232.5 42.9 51.4 57.0 75.0 44.5 41.6 76.7 115.4 101.7 331.0 35.9 41.2 38.0 63.7 46.7 121.8 66.9 69.2 47.1 109.1 58.0 23.4 36.1 42.8 89.5 89.6 237.2 127.2 75.8 50.8 52.9 40.5 1127.2 37.0 58.1 35.6 17.8 44.4 32.6 23.7 43.7 87.7 77.6 39.4 30.5 77.1 31.5 111.8 103.0 33.1 68.3 19.7 44.3 65.0 7.8 22.3 139.1 32.8 39.3 64.3 74.8 126.9 37.2 GPX1 ENSG00000233276 "Glutathione peroxidase 1" P07203 3 49357176-49358353 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3273.8;Kupffer cells: 3971.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1534.3;granulocytes: 1010.7;monocytes: 1337.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011582, HPA044758" Approved Supported Cytosol NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "CAB011582: AB_2112120, HPA044758: AB_2679076" "unprognostic (1.50e-2)" "unprognostic (4.34e-3)" "unprognostic (1.25e-1)" "prognostic favorable (7.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (6.73e-3)" "unprognostic (5.03e-2)" "unprognostic (3.40e-2)" "unprognostic (2.48e-1)" "unprognostic (5.46e-2)" "unprognostic (1.53e-1)" "unprognostic (7.64e-3)" "unprognostic (9.14e-3)" "unprognostic (3.16e-2)" "unprognostic (5.72e-3)" "unprognostic (7.64e-3)" 321.4 200.0 178.3 151.9 186.6 246.7 151.5 190.2 298.9 90.9 247.3 86.9 122.2 82.2 17.8 134.3 86.5 91.1 95.5 173.1 198.9 152.9 281.6 168.3 174.3 234.0 213.0 61.9 74.4 35.2 85.7 121.2 208.3 107.0 42.7 8.3 113.1 53.9 157.1 70.4 113.6 70.4 218.0 195.9 92.9 31.5 217.6 75.3 82.1 61.7 86.6 116.8 94.9 256.3 322.8 189.2 72.6 95.4 113.5 205.9 225.9 217.7 114.7 151.5 80.1 157.8 229.7 0.6 301.6 139.8 181.7 93.2 98.8 660.3 31.6 200.2 271.6 224.8 190.2 397.4 575.6 161.0 594.4 455.9 267.6 292.4 221.5 190.0 341.5 78.6 0.5 179.3 125.9 0.8 51.2 407.0 441.3 147.4 510.5 190.8 93.8 120.3 258.2 385.6 87.7 178.5 249.5 1.5 287.3 75.7 1.5 559.5 546.5 209.7 236.0 385.8 453.6 1.1 127.9 116.3 390.5 436.3 507.8 1010.7 1337.0 707.6 69.8 483.7 100.9 314.2 127.7 83.7 1093.1 276.8 118.4 116.2 136.4 107.4 275.8 1534.3 233.3 1401.2 178.3 186.6 190.2 298.9 173.1 198.9 234.0 213.0 208.3 218.0 217.6 256.3 0.0 109.0 323.5 6.2 148.1 249.7 432.8 985.0 92.2 32.1 0.0 0.0 0.0 220.2 616.7 0.0 10.4 499.9 491.5 229.5 0.0 0.0 300.7 0.0 0.0 227.8 251.3 364.1 12.8 0.0 830.3 131.0 73.4 0.0 480.6 0.0 585.7 888.1 3273.8 1.7 17.9 285.0 386.6 3971.6 965.7 1102.9 134.5 1305.5 273.9 41.2 828.6 63.4 138.0 8.0 7.6 0.0 179.0 67.0 82.4 481.0 349.9 0.0 490.0 14.6 210.4 150.6 151.8 12.7 169.4 112.1 154.1 278.8 112.2 0.0 367.3 517.0 GSS ENSG00000100983 "Glutathione synthetase" P48637 20 34928432-34956027 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 164.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054508, HPA059315" Enhanced Supported Nucleoplasm NA NA 28000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA054508: AB_2682509, HPA059315: AB_2683976" "unprognostic (5.80e-2)" "unprognostic (1.50e-1)" "unprognostic (1.14e-1)" "unprognostic (7.21e-2)" "unprognostic (3.63e-2)" "unprognostic (5.68e-2)" "prognostic unfavorable (7.21e-5)" "unprognostic (2.90e-2)" "unprognostic (8.52e-2)" "unprognostic (3.64e-1)" "unprognostic (6.49e-2)" "unprognostic (1.50e-1)" "prognostic favorable (7.31e-6)" "unprognostic (3.35e-3)" "unprognostic (1.96e-1)" "unprognostic (1.42e-3)" "unprognostic (1.52e-1)" 18.8 46.9 24.2 17.7 25.6 27.1 23.8 21.4 26.2 21.1 24.6 41.1 30.4 17.4 67.7 43.4 26.9 17.9 24.8 25.4 25.3 42.7 44.8 21.7 15.9 23.7 25.1 14.3 15.7 27.7 26.4 19.8 25.5 34.2 40.6 15.7 28.9 18.6 20.4 34.6 28.4 19.1 22.9 23.7 28.5 23.7 25.9 21.5 23.2 16.9 18.5 22.9 26.1 25.4 63.7 75.7 36.2 51.2 41.4 42.8 51.5 52.9 48.7 81.6 67.1 139.9 75.5 44.8 68.6 54.9 78.7 58.7 53.6 134.8 68.5 20.9 30.4 176.1 46.8 140.1 58.1 44.8 59.5 45.3 141.8 77.0 128.8 36.3 58.4 59.5 87.1 35.7 100.6 70.1 72.5 63.5 21.4 83.2 96.0 64.8 72.7 106.9 117.7 63.9 71.0 41.3 93.6 86.5 70.9 19.7 106.5 40.5 46.7 93.1 52.5 61.7 46.5 35.7 35.9 49.1 79.4 48.6 56.7 17.5 36.2 8.7 30.4 39.2 27.6 12.8 24.0 31.4 43.6 8.7 27.7 23.7 8.4 29.3 36.6 23.9 32.6 29.0 24.2 25.6 21.4 26.2 25.4 25.3 23.7 25.1 25.5 22.9 25.9 25.4 10.6 19.2 10.5 13.4 9.9 26.3 32.5 72.4 38.7 23.0 32.8 20.8 17.1 27.1 38.1 25.8 10.4 79.4 19.1 58.1 25.4 51.6 55.6 14.8 18.2 16.1 23.4 26.9 12.2 47.2 52.5 19.3 37.2 16.4 17.7 80.1 10.0 27.3 59.9 35.3 13.8 50.6 48.8 17.2 17.3 164.1 10.2 26.8 16.0 5.6 31.0 29.6 19.6 10.1 9.9 39.8 40.1 18.4 19.6 21.4 33.8 121.5 18.1 16.9 26.3 12.0 21.0 14.7 18.9 38.1 24.2 49.0 20.6 52.1 77.7 33.0 HBA1 HBA-T3 ENSG00000206172 "Hemoglobin subunit alpha 1" P69905 16 176680-177522 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "bone marrow: 24344.4" "Cell type enriched" "Detected in many" 51 "Erythroid cells: 224916.4" "Group enriched" "Detected in many" 4 "endometrial cancer: 2.6;glioma: 6.3;ovarian cancer: 2.6;stomach cancer: 2.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 142.6;plasmacytoid DC: 101.1" "Group enriched" "Detected in all" 5 "dendritic cells: 101.1;granulocytes: 142.6" "Group enriched" "Detected in some" 36 "HEL: 3355.8;K-562: 2416.8" "CAB032534, HPA043780" Enhanced NA NA 14000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "CAB032534: AB_2294993, HPA043780: AB_2678667" "unprognostic (1.16e-1)" "unprognostic (1.45e-2)" "unprognostic (8.87e-2)" "unprognostic (9.78e-3)" "unprognostic (3.02e-1)" "unprognostic (1.44e-1)" "unprognostic (1.67e-1)" "unprognostic (1.35e-1)" "unprognostic (6.21e-3)" "unprognostic (1.92e-2)" "unprognostic (1.64e-1)" "unprognostic (1.02e-2)" "unprognostic (3.59e-2)" "unprognostic (3.79e-1)" "unprognostic (6.61e-2)" "unprognostic (2.67e-2)" "unprognostic (9.56e-2)" 893.7 183.0 112.1 82.0 216.3 24344.4 316.6 159.4 246.9 237.7 340.5 141.4 10.6 41.4 2.4 244.9 350.9 60.1 1766.9 56.9 92.1 1405.5 1100.4 2201.7 5.0 141.5 169.4 159.7 100.5 5.1 465.7 1992.7 183.4 170.1 11.5 3.1 138.1 43.7 234.0 194.6 85.0 7.0 211.1 5527.7 135.9 104.8 125.3 20.7 609.2 1123.2 3.6 167.2 351.2 113.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 58.1 0.0 5.7 2.1 0.0 0.4 0.0 3.5 0.0 0.0 0.0 0.2 3355.8 0.0 37.1 0.0 1.3 0.0 0.3 0.0 0.0 0.7 0.0 0.0 1.7 2416.8 0.0 0.0 14.7 0.5 0.3 0.4 1.0 0.0 0.1 1.4 79.1 0.0 1.0 7.4 5.3 2.8 0.0 0.0 0.0 1.1 0.0 8.3 0.0 0.0 0.9 0.0 0.0 0.4 0.8 0.0 0.2 0.0 8.5 7.4 48.2 26.3 0.2 0.7 7.5 3.1 8.7 10.0 4.5 8.3 25.7 142.6 13.4 0.8 101.1 0.3 2806.3 112.1 216.3 159.4 246.9 56.9 92.1 141.5 169.4 183.4 211.1 125.3 113.5 72.7 0.0 0.0 0.0 56.8 10.6 0.1 0.0 0.0 0.4 11.3 12.3 1.8 55.8 0.1 0.0 0.0 0.0 93.2 3.2 7.9 0.0 6.0 0.5 0.5 20.4 1.2 224916.4 0.0 0.0 0.0 57.9 0.0 0.4 0.0 0.1 151.0 78.8 0.0 0.0 0.0 5.7 0.0 436.7 64.1 22.4 0.0 234.0 4338.2 0.0 12.7 1.3 1166.9 0.0 0.0 0.1 2.8 0.4 0.5 0.2 0.2 11.1 0.0 16.5 0.0 8.7 58.7 1.5 7.6 0.0 13.2 0.0 155.7 0.0 3.2 0.0 HBA2 HBA-T2 ENSG00000188536 "Hemoglobin subunit alpha 2" P69905 16 172876-173710 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 38218.6" "Cell type enriched" "Detected in many" 22 "Erythroid cells: 198314.0" "Cancer enhanced" "Detected in all" "glioma: 59.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 315.1;neutrophil: 955.3;plasmacytoid DC: 486.7" "Group enriched" "Detected in all" 7 "dendritic cells: 486.7;granulocytes: 955.3" "Group enriched" "Detected in some" 18 "HEL: 1196.2;K-562: 328.3" "CAB038417, HPA043780" Enhanced NA NA 14000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "CAB038417: , HPA043780: AB_2678667" "unprognostic (1.57e-1)" "unprognostic (7.02e-2)" "unprognostic (2.59e-2)" "unprognostic (2.13e-1)" "unprognostic (3.59e-1)" "unprognostic (3.18e-1)" "unprognostic (3.39e-2)" "unprognostic (2.12e-1)" "unprognostic (4.99e-2)" "unprognostic (4.43e-1)" "unprognostic (1.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.72e-3)" "unprognostic (1.36e-1)" "unprognostic (2.11e-1)" "unprognostic (4.73e-2)" "unprognostic (8.92e-2)" 1592.0 322.5 162.6 186.3 292.4 38218.6 545.3 268.0 377.0 573.3 570.7 254.0 21.6 85.9 5.9 432.5 570.5 147.6 2590.3 86.6 156.5 2302.8 1853.6 4204.3 9.7 210.6 249.2 288.5 141.3 11.4 807.8 3618.9 260.6 302.7 26.7 4.0 305.4 131.9 568.3 188.5 154.3 12.9 316.4 8125.4 264.0 185.0 185.4 34.6 1192.5 1744.6 10.1 325.2 632.8 179.9 0.0 0.2 0.0 0.0 0.0 0.7 0.4 0.4 0.1 0.0 0.0 3.2 0.0 1.9 4.9 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.6 1196.2 0.5 0.0 0.0 0.2 1.7 0.4 0.1 0.4 0.0 0.0 0.0 0.1 328.3 0.0 0.1 0.6 0.0 0.3 0.1 0.5 0.0 0.0 0.0 43.4 0.0 0.9 11.9 9.7 1.1 0.0 0.0 0.1 1.4 0.2 5.6 0.0 0.3 0.4 0.0 0.4 0.0 0.0 0.3 0.6 0.2 119.6 28.1 315.1 99.6 1.7 3.7 39.2 8.5 7.1 42.5 19.1 22.8 73.9 955.3 49.5 3.3 486.7 1.0 15003.3 162.6 292.4 268.0 377.0 86.6 156.5 210.6 249.2 260.6 316.4 185.4 179.9 184.7 3.2 1.5 0.0 97.6 44.4 0.4 0.1 0.6 1.7 20.2 22.2 6.8 70.1 0.7 0.0 0.0 0.0 162.2 6.9 54.8 0.0 3.4 0.6 0.8 50.9 3.0 198314.0 0.0 0.0 0.0 241.0 4.1 0.9 1.3 0.3 142.8 131.2 0.0 0.0 0.0 7.5 4.1 770.6 149.6 16.9 0.0 402.9 8790.3 0.0 37.5 2.3 954.7 0.0 0.0 0.0 3.6 0.0 0.3 0.2 0.1 29.6 2.5 58.6 0.0 25.2 171.5 1.0 9.9 1.1 44.6 0.0 306.3 0.1 5.0 0.1 HBB "beta-globin, CD113t-C" ENSG00000244734 "Hemoglobin subunit beta" P68871 11 5225464-5229395 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Hypotensive agent, Vasoactive" "Congenital dyserythropoietic anemia, Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "bone marrow: 133301.6" "Cell type enriched" "Detected in many" 24 "Erythroid cells: 672352.3" "Group enriched" "Detected in all" 4 "cervical cancer: 66.4;glioma: 244.6;renal cancer: 65.1" "Region enriched" "Detected in all" 11 "cerebral cortex: 3368.5" "Group enriched" "Detected in all" 5 "neutrophil: 658.1;plasmacytoid DC: 379.7" "Group enriched" "Detected in all" 11 "dendritic cells: 379.7;granulocytes: 658.1" "Cell line enhanced" "Detected in some" "HEL: 6.0;SCLC-21H: 5.0;SH-SY5Y: 6.4;U-266/70: 23.1;U-266/84: 4.2" "CAB009526, HPA043234" Enhanced NA NA 10000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 6: Erythroid cells - Oxygen transport" "CAB009526: AB_2143058, HPA043234: AB_2678378" "unprognostic (2.41e-1)" "unprognostic (8.55e-2)" "unprognostic (2.40e-1)" "unprognostic (4.40e-2)" "unprognostic (1.14e-1)" "unprognostic (3.22e-1)" "unprognostic (4.88e-2)" "unprognostic (7.46e-2)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (8.11e-3)" "unprognostic (2.40e-2)" "unprognostic (5.81e-2)" "unprognostic (1.42e-1)" "unprognostic (8.87e-3)" "unprognostic (6.41e-2)" 1641.5 481.4 155.7 217.3 219.2 133301.6 637.4 235.7 3368.5 546.2 384.6 278.2 28.8 78.8 45.6 505.7 829.6 792.7 2658.8 108.9 154.4 2333.1 1907.3 4039.6 26.8 209.6 243.5 289.0 158.5 50.5 808.2 6345.0 303.0 312.0 148.9 31.0 548.1 290.6 578.8 135.3 169.8 66.3 316.2 9225.9 269.1 170.6 171.4 196.8 1152.0 12902.5 40.3 320.1 633.5 180.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.2 0.0 0.0 0.0 0.8 0.2 0.4 0.0 0.0 0.4 0.3 0.0 0.0 5.0 6.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 23.1 4.2 0.0 0.0 0.0 0.0 99.5 25.3 73.7 37.8 1.3 4.0 21.5 6.8 1.1 35.2 13.8 13.7 39.9 658.1 47.9 5.0 379.7 1.4 22388.9 155.7 219.2 235.7 3368.5 108.9 154.4 209.6 243.5 303.0 316.2 171.4 180.7 441.7 3.2 8.4 0.0 280.5 157.0 2.3 5.1 0.0 4.0 54.7 72.0 3.4 217.3 4.5 7.3 4.2 2.2 369.9 5.2 50.9 0.0 0.0 6.8 6.6 151.7 3.6 672352.3 0.0 0.0 11.3 276.1 0.0 5.1 0.0 4.6 443.4 420.5 7.3 3.3 0.0 7.2 6.1 1452.1 702.6 0.0 0.0 1091.0 27383.1 0.0 72.7 9.7 38.1 0.0 0.0 0.1 3.5 0.0 1.9 0.0 0.1 272.4 84.9 117.8 0.0 126.0 396.8 0.0 0.0 0.0 252.5 2.2 769.8 0.3 3.0 0.1 HBG1 HBG-T2 ENSG00000213934 "Hemoglobin subunit gamma 1" P69891 11 5248269-5249857 "Human disease related genes, Predicted intracellular proteins" "Oxygen transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 66 "placenta: 367.3" "Cell type enriched" "Detected in single" 76 "Macrophages: 22.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 48 "K-562: 3611.8" HPA043234 Approved NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 51: Myeloid cells - Hemostasis" "HPA043234: AB_2678378" "unprognostic (3.17e-2)" 1.5 0.5 0.1 0.0 0.2 0.3 0.5 0.1 0.7 1.0 0.1 0.4 0.2 0.4 0.0 0.4 0.3 0.0 2.1 0.1 0.2 1.3 1.3 3.0 0.0 0.3 0.2 0.4 0.4 0.0 0.6 367.3 0.3 0.4 0.0 0.0 0.2 0.0 0.9 0.3 0.3 0.0 0.1 5.5 0.4 0.2 0.1 0.9 1.0 2.3 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3611.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.1 0.2 0.1 0.7 0.1 0.2 0.3 0.2 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 HBG2 HBG-T1 ENSG00000196565 "Hemoglobin subunit gamma 2" P69892 11 5253188-5505605 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Oxygen transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 132 "placenta: 10310.3" "Group enriched" "Detected in some" 17 "Erythroid cells: 66.1;Macrophages: 74.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 192 "HEL: 8197.4;K-562: 8088.4" "CAB016143, HPA043234" Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 51: Myeloid cells - Hemostasis" "CAB016143: AB_2295004, HPA043234: AB_2678378" "unprognostic (4.48e-3)" "unprognostic (2.42e-1)" "unprognostic (6.24e-2)" "unprognostic (1.41e-1)" "unprognostic (8.94e-2)" "unprognostic (4.22e-1)" "unprognostic (5.29e-1)" "unprognostic (3.95e-2)" "unprognostic (2.99e-1)" "unprognostic (3.52e-2)" "unprognostic (4.27e-1)" "unprognostic (3.75e-2)" "unprognostic (7.70e-5)" "unprognostic (1.64e-1)" "unprognostic (2.65e-1)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" 6.8 1.6 1.6 0.5 2.0 78.2 2.5 1.5 4.7 4.2 2.0 2.8 1.4 1.1 0.5 2.0 2.0 5.3 8.2 1.8 1.1 5.9 6.1 16.4 0.3 1.1 1.2 2.2 9.3 0.8 3.1 10310.3 1.1 1.5 0.1 0.4 3.7 0.2 4.2 1.2 0.9 4.4 0.7 27.3 3.3 0.8 1.2 2.4 4.8 0.6 0.4 0.4 3.1 2.0 0.4 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.3 1.4 0.0 0.2 23.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 8197.4 0.5 0.4 0.0 1.5 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 8088.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 8.0 8.9 1.9 0.1 0.3 0.2 0.0 0.0 42.3 0.1 0.6 3.0 0.1 0.6 1.9 1.9 0.0 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 6.5 1.6 2.0 1.5 4.7 1.8 1.1 1.1 1.2 1.1 0.7 1.2 2.0 2.2 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 1.5 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 1.8 0.0 0.0 1.0 0.0 66.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 1.4 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.6 0.3 74.6 0.0 0.0 1.5 0.0 1.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.3 0.2 1.5 0.9 0.0 0.0 0.0 0.6 0.3 0.0 0.1 HK1 ENSG00000156515 "Hexokinase 1" P19367 10 69269984-69401884 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycolysis, Immunity, Inflammatory response, Innate immunity" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Mental retardation, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 374.0;Horizontal cells: 304.5;Late spermatids: 1034.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007043, HPA007044, CAB010052" Supported Supported Mitochondria NA NA 560000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "CAB010052: AB_627721, HPA007043: AB_1850652, HPA007044: AB_1079049" "unprognostic (8.80e-2)" "unprognostic (1.78e-1)" "unprognostic (2.03e-1)" "unprognostic (2.00e-3)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.37e-3)" "unprognostic (7.25e-2)" "unprognostic (1.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.86e-2)" 47.0 24.4 61.0 45.0 65.7 60.3 40.6 58.0 76.6 54.7 64.2 60.1 13.1 41.3 11.2 129.9 37.0 25.7 150.8 69.1 62.7 49.2 8.5 48.1 34.1 56.7 59.8 19.9 12.3 25.0 44.9 49.3 71.1 52.9 31.9 147.6 67.1 53.1 193.5 102.6 29.2 49.8 40.0 40.3 61.6 77.2 53.5 44.9 71.0 146.7 47.6 74.3 80.9 54.1 101.6 56.6 74.2 71.1 81.0 60.4 47.1 98.3 256.5 128.5 138.0 16.3 11.0 7.3 75.8 165.9 92.9 86.2 69.9 220.0 122.0 67.5 54.5 250.0 58.3 1.1 91.7 5.1 181.2 91.5 125.8 184.5 407.6 160.8 135.4 36.8 424.5 51.3 178.7 167.7 29.7 13.1 113.8 51.7 247.0 44.8 45.0 0.6 88.7 117.4 75.7 88.7 112.6 215.4 65.2 104.3 117.7 16.5 140.4 190.5 86.4 106.5 139.6 61.1 42.8 17.4 247.3 130.4 56.1 68.7 88.8 44.6 41.5 125.2 69.0 33.5 47.9 47.6 81.0 19.9 41.7 33.9 20.9 31.2 135.4 9.1 58.1 110.4 61.0 65.7 58.0 76.6 69.1 62.7 56.7 59.8 71.1 40.0 53.5 54.1 26.1 25.6 32.4 38.2 26.5 48.3 50.5 37.8 43.9 83.9 33.1 21.7 130.6 4.3 34.2 27.6 54.2 70.6 14.6 30.3 13.7 28.6 374.0 32.6 28.0 37.9 18.7 104.8 53.8 30.6 93.3 30.3 41.3 34.5 23.4 72.6 26.7 1.1 49.4 304.5 49.8 28.7 44.7 41.7 21.9 1034.1 15.2 51.3 37.4 29.0 35.3 32.9 20.6 14.1 3.5 54.6 11.1 18.4 19.1 29.1 0.7 1.1 30.7 95.5 19.7 22.2 43.1 5.3 6.2 86.0 51.7 118.9 30.5 28.3 19.3 43.5 HRG "HPRG, HRGP" ENSG00000113905 "Histidine rich glycoprotein" P04196 3 186660216-186678234 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Blood coagulation, Chemotaxis, Fibrinolysis, Hemostasis" Heparin-binding "Disease variant, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 173 "liver: 5433.2" "Cell type enriched" "Detected in some" 29 "Hepatocytes: 479.7" "Cancer enriched" "Detected in some" 262 "liver cancer: 406.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 2.7;RH-30: 3.0;SiHa: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050269, HPA054598" Supported "Secreted to blood" NA NA 120000000000 28000000000 "Cluster 62: Liver - Hemostasis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 15: Hepatocytes - Hemostasis" "HPA050269: AB_2681068, HPA054598: AB_2682539" "unprognostic (2.67e-1)" "unprognostic (1.74e-2)" "unprognostic (7.58e-5)" "prognostic favorable (9.64e-5)" "unprognostic (1.44e-1)" "unprognostic (2.98e-3)" "unprognostic (2.22e-1)" "unprognostic (1.55e-2)" "unprognostic (1.14e-1)" "unprognostic (5.50e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 31.4 5433.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 3.0 0.0 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.7 0.0 3.7 0.0 0.0 0.0 0.0 5.9 0.0 0.1 0.0 0.0 0.6 0.0 10.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.7 479.7 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1" O75874 2 208236229-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 536.3" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 320.2;Granulosa cells: 257.5;Hepatocytes: 328.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 768.1;RT4: 524.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 16000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies, Cytosol" "CAB033218: AB_2123166, CAB062556: AB_2665593, HPA035248: AB_10600714, HPA057936: AB_2683559" "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (6.93e-5)" "unprognostic (3.32e-1)" "unprognostic (2.20e-3)" "unprognostic (8.03e-2)" "unprognostic (5.54e-2)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.45e-5)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" 150.8 230.8 24.0 37.5 23.9 10.7 63.0 24.6 30.9 67.9 40.8 124.9 179.4 22.9 164.9 92.2 36.6 69.5 25.3 23.5 26.1 122.0 536.3 49.8 33.3 26.4 25.7 84.4 39.9 42.0 16.7 82.5 25.9 214.6 131.2 35.0 59.3 79.1 25.7 23.6 117.4 43.8 25.5 40.1 113.6 57.0 30.0 21.8 45.5 28.1 29.8 153.1 39.9 30.6 66.5 109.6 152.5 63.3 275.1 191.4 86.7 26.3 122.3 44.2 107.3 176.1 159.1 13.1 168.8 84.4 181.6 101.4 112.4 130.7 43.0 8.8 41.7 56.7 87.3 768.1 367.3 37.0 54.7 169.5 278.0 102.7 74.2 69.8 126.1 37.2 58.1 44.5 68.9 42.8 26.3 66.2 284.5 479.7 43.9 25.2 54.8 37.8 206.3 524.0 25.9 45.2 100.5 99.7 351.7 161.2 37.9 111.0 81.1 45.2 44.1 65.3 29.6 20.8 34.5 16.9 148.2 226.7 37.0 12.4 70.1 11.0 9.1 32.3 10.6 10.6 8.2 10.9 50.9 10.1 6.7 7.8 13.8 17.2 15.5 18.8 15.1 29.9 24.0 23.9 24.6 30.9 23.5 26.1 26.4 25.7 25.9 25.5 30.0 30.6 13.9 12.8 49.5 39.2 20.2 12.4 18.8 60.5 52.3 19.5 61.8 31.5 21.8 45.8 69.1 29.5 25.0 320.2 23.7 106.8 21.5 31.1 13.8 31.0 23.4 22.0 58.4 30.3 16.6 86.5 178.8 29.6 76.0 108.8 14.0 257.5 39.7 328.2 175.3 11.8 16.2 98.4 57.0 130.2 23.8 11.2 24.5 71.7 26.6 19.7 47.8 25.4 18.6 66.4 20.0 44.8 55.5 29.3 13.7 53.2 181.2 108.5 21.9 56.6 13.1 7.8 23.6 8.0 26.2 82.4 14.9 95.6 19.8 127.1 129.3 46.7 IDH2 ENSG00000182054 "Isocitrate dehydrogenase (NADP(+)) 2" P48735 15 90083045-90102477 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 492.6;skeletal muscle: 1302.3;tongue: 1611.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 732.5;Distal tubular cells: 1168.0;Extravillous trophoblasts: 586.7;Syncytiotrophoblasts: 573.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 425.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007831 Enhanced Supported Mitochondria NA NA 5200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA007831: AB_1851397" "unprognostic (2.45e-2)" "prognostic favorable (5.15e-5)" "unprognostic (2.92e-1)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (8.46e-2)" "unprognostic (3.83e-2)" "unprognostic (2.55e-3)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.76e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-3)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" 32.8 10.5 56.5 60.2 67.8 161.1 51.1 57.1 59.8 36.6 76.6 95.9 97.2 29.0 12.5 140.6 32.7 31.7 492.6 47.2 55.0 208.3 274.7 32.0 77.1 61.0 61.3 13.6 128.7 104.0 15.5 87.3 54.4 76.2 84.1 5.4 163.1 90.4 1302.3 61.8 84.3 79.8 52.9 36.8 175.7 5.3 71.6 148.7 16.0 1611.3 66.0 53.3 49.4 57.6 61.3 33.5 169.9 169.8 23.3 28.3 144.5 74.5 110.8 68.0 72.6 16.1 51.1 72.7 21.0 61.2 65.1 20.8 25.1 22.4 32.0 143.8 16.9 122.9 12.7 119.7 28.1 85.1 118.2 59.7 12.7 16.3 13.0 82.1 141.0 246.4 18.9 59.3 53.0 175.3 425.0 131.2 51.8 81.9 14.3 352.0 122.4 213.7 105.6 71.3 244.5 125.3 92.1 359.8 29.9 94.2 290.9 256.9 34.0 120.4 17.0 16.1 34.9 101.5 20.5 9.0 38.4 175.0 71.2 45.0 112.8 75.6 105.9 199.1 53.2 70.1 77.0 120.1 136.9 47.7 42.9 71.8 22.9 99.9 252.1 79.4 72.4 163.4 56.5 67.8 57.1 59.8 47.2 55.0 61.0 61.3 54.4 52.9 71.6 57.6 16.9 6.4 21.0 40.1 64.2 39.9 98.8 91.6 12.5 6.2 90.5 48.1 445.9 114.4 95.8 75.4 10.4 732.5 84.0 70.0 1168.0 252.8 5.6 96.4 25.7 41.6 61.7 193.8 11.8 288.8 586.7 44.7 88.2 50.9 31.6 29.2 38.2 283.1 263.7 10.1 8.3 158.3 229.9 77.7 101.1 3.2 14.0 79.0 58.7 5.6 85.3 20.9 119.4 16.6 27.3 116.6 105.0 35.3 185.9 170.3 69.6 205.0 167.9 5.4 13.1 60.8 73.4 0.6 15.6 113.3 67.1 573.0 88.1 14.7 305.1 140.1 IFNG ENSG00000111537 "Interferon gamma" P01579 12 68154768-68159740 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense, Growth regulation" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.5;lymphoid tissue: 7.4" "Group enriched" "Detected in many" 12 "dendritic cells: 283.2;T-cells: 200.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "gdT-cell: 5.5;memory CD4 T-cell: 2.4;memory CD8 T-cell: 6.6;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB010344 Approved "Secreted to blood" NA NA 1470 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 7: Non-specific - Mitochondria" "CAB010344: AB_2123447" "unprognostic (2.16e-4)" "unprognostic (1.93e-3)" "unprognostic (9.21e-2)" "unprognostic (1.04e-4)" "unprognostic (5.14e-1)" "unprognostic (3.96e-3)" "unprognostic (1.33e-1)" "unprognostic (3.17e-4)" "unprognostic (7.79e-2)" "unprognostic (7.97e-3)" "unprognostic (1.63e-2)" "unprognostic (5.36e-2)" "unprognostic (7.62e-9)" "unprognostic (3.54e-2)" "unprognostic (5.36e-1)" "unprognostic (6.32e-2)" "unprognostic (7.38e-3)" 0.7 0.7 0.1 3.5 0.2 11.5 0.3 0.0 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.0 0.0 0.3 1.5 1.8 7.4 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.9 0.2 0.0 0.0 0.3 0.2 0.0 1.3 0.4 0.1 0.1 0.5 0.3 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 2.4 6.6 0.0 0.4 0.5 3.7 0.1 0.9 0.0 0.0 0.1 0.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.7 0.0 0.0 0.0 3.1 3.2 1.3 0.0 0.0 0.0 4.8 5.5 0.2 1.5 0.0 0.0 0.0 0.0 283.2 0.1 0.0 0.0 0.2 1.0 1.1 1.3 0.0 0.4 0.0 0.0 0.0 1.5 6.1 1.1 0.0 0.0 1.4 1.2 0.1 0.0 0.0 0.5 0.0 4.4 5.5 0.0 0.0 10.4 7.2 0.0 0.0 0.0 19.6 0.0 0.1 0.0 1.1 0.0 10.9 0.2 0.0 0.3 0.0 0.0 0.0 1.0 2.9 0.0 0.0 0.8 4.0 0.0 200.1 0.0 0.2 0.2 ITGA2 CD49B ENSG00000164171 "Integrin subunit alpha 2" P17301 5 52989340-53094779 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 406.2;Oligodendrocytes: 370.9;Pancreatic endocrine cells: 558.7;Prostatic glandular cells: 299.3;Urothelial cells: 363.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 91.4;HaCaT: 92.5;hTERT-RPE1: 83.2;HUVEC TERT2: 83.5;TIME: 71.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017690, HPA060991, HPA063556" Enhanced Approved Nucleoplasm,Cytosol Yes No 43000000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "CAB017690: AB_1124939, HPA060991: AB_2684405, HPA063556: AB_2685040" "unprognostic (8.35e-2)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "unprognostic (1.07e-1)" "unprognostic (1.22e-1)" "unprognostic (3.70e-2)" "unprognostic (2.67e-3)" "unprognostic (2.38e-2)" "unprognostic (1.87e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (4.27e-1)" "unprognostic (3.88e-2)" "unprognostic (2.87e-2)" "unprognostic (1.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.11e-1)" 1.4 12.8 2.4 4.9 6.7 0.4 7.8 4.4 3.7 5.0 0.9 6.1 7.7 4.9 7.4 11.0 2.6 9.0 1.1 2.4 4.2 9.8 0.5 12.5 0.9 4.8 4.9 1.0 1.6 9.3 1.2 4.8 5.4 6.6 5.9 2.4 10.4 11.1 0.5 17.1 7.7 2.4 3.3 6.8 7.5 0.4 4.8 4.3 2.3 0.7 4.6 15.6 8.0 12.9 60.4 15.4 1.3 0.8 3.9 7.1 4.5 60.2 91.4 2.2 3.6 29.0 41.8 0.1 9.8 25.4 33.5 92.5 4.9 67.1 8.5 0.0 4.4 4.3 3.7 17.5 13.3 0.7 1.3 2.9 11.4 59.2 10.5 83.2 83.5 3.1 0.1 0.2 1.6 11.4 0.6 0.1 3.7 15.7 29.6 0.0 0.4 0.1 18.9 32.0 0.6 3.2 3.2 4.1 6.1 2.3 9.6 0.2 71.2 10.8 6.3 1.7 12.1 0.0 0.1 0.1 64.0 0.0 48.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.4 6.7 4.4 3.7 2.4 4.2 4.8 4.9 5.4 3.3 4.8 12.9 7.4 57.7 13.7 9.1 0.6 151.0 406.2 141.3 56.9 2.7 24.4 39.0 1.3 15.7 133.2 53.3 4.2 1.9 0.9 23.2 9.8 144.0 0.1 20.3 5.0 39.0 13.8 0.0 0.5 169.3 2.2 11.6 13.3 90.6 1.3 45.4 5.3 0.2 0.3 0.0 0.9 37.8 20.3 0.0 6.1 0.2 1.2 2.5 12.4 14.0 1.1 14.7 0.0 0.0 370.9 558.7 20.3 0.0 2.6 299.3 20.6 3.8 103.6 4.3 0.0 4.4 12.1 0.0 1.3 57.0 37.2 0.4 5.8 23.7 30.9 363.9 ITGA2B "CD41, CD41B, GP2B, PPP1R93" ENSG00000005961 "Integrin subunit alpha 2b" P08514 17 44372180-44389649 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.6;epididymis: 10.7;lymphoid tissue: 11.2" "Cell type enhanced" "Detected in many" "Early spermatids: 16.1;Erythroid cells: 43.5;granulocytes: 17.8;Late spermatids: 24.8;Macrophages: 23.0" "Cancer enhanced" "Detected in some" "testis cancer: 2.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "basophil: 64.5" "Lineage enriched" "Detected in single" 75 "granulocytes: 64.5" "Group enriched" "Detected in some" 14 "HEL: 404.6;HMC-1: 631.7" "Not detected" "Not detected" "CAB018611, HPA031168, HPA031169, HPA031170, HPA031171" Enhanced Approved "Plasma membrane" NA NA 90000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "CAB018611: AB_2265153, HPA031168: AB_10664706, HPA031169: AB_10669671, HPA031170: AB_10696214, HPA031171: AB_10669773" "unprognostic (6.11e-2)" "unprognostic (3.23e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-2)" "unprognostic (1.59e-2)" "unprognostic (3.98e-3)" "unprognostic (4.23e-5)" "unprognostic (1.25e-1)" "unprognostic (1.33e-2)" "unprognostic (7.22e-2)" "unprognostic (2.97e-3)" "unprognostic (1.30e-1)" "unprognostic (8.83e-9)" "unprognostic (7.82e-2)" "unprognostic (1.85e-1)" "unprognostic (1.95e-1)" "unprognostic (2.25e-1)" 0.8 0.2 3.7 0.2 3.6 16.6 0.4 4.0 4.8 1.5 3.8 0.3 0.0 0.9 10.7 0.3 1.5 0.8 1.4 3.5 3.6 1.0 0.5 5.1 0.2 3.6 3.5 1.5 0.1 1.3 1.9 1.1 3.6 0.6 0.1 1.6 0.1 0.8 0.6 0.1 0.3 0.2 3.3 11.2 0.3 2.9 3.5 0.1 3.1 1.1 0.1 0.2 0.7 3.7 0.5 0.7 2.2 0.3 0.1 0.3 18.4 0.3 0.1 0.8 0.6 0.0 0.2 0.0 0.3 0.0 0.2 0.6 1.8 0.0 0.4 0.4 1.1 404.6 0.3 1.3 0.0 0.2 631.7 0.4 0.0 0.2 0.0 0.0 0.0 0.3 0.7 1.1 0.0 0.7 0.5 36.4 0.8 0.0 0.7 0.7 0.2 0.0 0.0 0.1 0.4 1.0 0.5 0.5 0.1 1.5 4.5 0.9 0.3 0.2 0.7 0.0 0.0 0.4 0.2 0.3 0.4 0.3 0.8 64.5 0.3 4.0 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 4.5 0.0 0.0 0.8 0.0 19.3 3.7 3.6 4.0 4.8 3.5 3.6 3.6 3.5 3.6 3.3 3.5 3.7 0.3 0.0 1.5 1.0 0.4 0.3 0.4 0.1 1.8 5.1 0.2 1.1 1.5 1.5 1.3 5.5 8.4 1.3 0.1 0.6 0.0 0.0 16.1 1.0 0.7 2.1 0.0 43.5 4.1 0.0 1.4 1.1 0.0 3.2 17.8 0.1 3.6 0.0 0.2 3.3 2.8 0.0 0.0 3.1 0.7 24.8 1.8 23.0 0.0 1.0 2.9 1.3 0.0 9.5 4.6 0.1 0.0 1.9 0.1 0.3 0.0 0.0 0.0 3.0 0.0 1.8 0.7 3.4 7.4 0.5 0.0 0.7 0.6 0.1 0.3 0.3 ITGB3 "CD61, GP3A, GPIIIa" ENSG00000259207 "Integrin subunit beta 3" P05106 17 47253827-47313743 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 51.4" "Cell type enhanced" "Detected in some" "Early spermatids: 3.9;Late spermatids: 8.8;Macrophages: 15.8;Proximal tubular cells: 4.6;Sertoli cells: 6.6" "Group enriched" "Detected in many" 6 "melanoma: 7.5;renal cancer: 3.6;thyroid cancer: 11.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 19 "basophil: 5.4;neutrophil: 2.5" "Lineage enriched" "Detected in single" 26 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "EFO-21: 167.8;HEL: 163.4;RPTEC TERT1: 109.8;U-87 MG: 78.3;WM-115: 255.9" HPA027852 Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 38000000 "Cluster 34: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" Nucleoplasm "HPA027852: AB_10601760" "unprognostic (1.13e-2)" "unprognostic (1.97e-3)" "unprognostic (2.47e-1)" "unprognostic (3.00e-2)" "unprognostic (1.91e-2)" "unprognostic (6.04e-3)" "unprognostic (3.70e-1)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-1)" "unprognostic (6.35e-2)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.03e-2)" "unprognostic (2.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-3)" 8.0 0.6 0.3 9.5 0.7 6.2 5.3 0.7 1.0 3.8 1.0 16.9 3.5 13.2 2.6 4.2 7.6 3.5 5.5 0.5 0.8 15.0 3.4 5.6 0.9 2.3 1.0 1.5 0.7 1.2 1.2 4.5 2.0 4.8 7.0 0.9 2.6 16.1 1.5 2.7 5.8 22.9 1.2 2.9 3.8 2.5 1.2 0.3 51.4 2.4 1.2 9.6 2.6 1.1 0.1 1.5 0.7 0.1 8.6 3.8 0.1 4.7 23.1 9.6 8.6 0.3 0.1 0.6 167.8 1.2 13.4 0.0 0.1 0.0 12.6 3.4 0.0 163.4 0.5 0.0 7.8 0.0 0.2 3.4 0.0 54.6 1.4 6.7 43.6 2.5 0.5 0.3 2.1 0.0 1.0 0.1 0.1 0.0 0.8 0.0 4.2 0.0 109.8 0.2 0.0 0.5 5.6 0.0 33.2 8.8 0.1 0.2 47.1 2.1 2.4 1.3 11.7 0.2 0.1 1.1 78.3 0.0 255.9 5.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.1 0.1 0.1 0.0 6.8 0.3 0.7 0.7 1.0 0.5 0.8 2.3 1.0 2.0 1.2 1.2 1.1 1.3 0.0 0.0 0.0 0.5 0.1 0.2 0.9 0.0 0.0 0.1 0.3 0.8 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 3.9 0.8 0.9 3.1 0.0 0.0 0.4 0.4 0.0 2.1 0.0 0.9 0.0 0.6 1.8 0.7 0.8 0.0 0.6 0.0 0.0 0.3 0.7 8.8 0.3 15.8 0.0 1.0 0.4 0.0 0.0 0.0 0.4 1.5 0.0 1.2 0.0 0.3 0.0 4.6 0.2 0.0 6.6 0.3 2.1 0.0 2.0 0.1 0.4 1.2 0.3 0.4 0.0 0.2 JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5129948 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.4;Inhibitory neurons: 122.3;Microglial cells: 106.8;Oligodendrocyte precursor cells: 69.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 132.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 132.5" "Group enriched" "Detected in many" 5 "ASC diff: 42.2;HDLM-2: 75.0;HEL: 154.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" No No "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: AB_2677151, HPA043870: AB_2678708" "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" 15.6 7.6 3.2 19.2 3.7 21.7 8.9 6.3 9.1 8.5 1.1 6.7 6.5 11.3 8.6 8.8 8.0 10.5 24.5 2.7 3.1 6.8 4.5 10.9 18.2 3.3 1.8 11.5 3.8 6.5 2.9 11.0 2.0 6.8 6.5 12.8 4.0 6.2 9.8 11.2 7.7 9.5 3.5 17.6 13.4 9.8 1.7 7.5 4.8 8.9 12.7 11.7 9.1 3.9 6.8 3.7 3.7 6.3 42.2 12.4 1.1 9.1 8.6 7.2 4.6 1.2 2.0 0.3 2.1 5.4 5.4 2.3 4.4 5.1 4.9 75.0 1.4 154.7 7.6 1.7 10.0 10.5 7.1 9.5 2.1 2.8 4.5 7.6 6.6 5.1 10.9 17.4 11.6 2.2 2.9 12.8 3.3 3.3 4.3 5.1 8.2 2.2 4.7 3.5 4.2 2.4 2.6 3.5 2.8 3.6 2.0 15.4 13.1 10.2 3.6 10.7 6.4 3.1 6.4 1.5 13.6 4.7 5.3 132.5 20.5 38.2 5.6 20.1 4.5 5.6 4.1 3.1 26.5 4.9 2.2 2.8 19.2 9.6 16.4 9.7 4.5 7.7 3.2 3.7 6.3 9.1 2.7 3.1 3.3 1.8 2.0 3.5 1.7 3.9 14.3 16.0 7.9 31.6 12.9 9.7 3.3 4.9 10.8 8.0 5.2 3.4 30.0 0.0 6.7 7.3 8.4 1.9 13.9 11.7 1.9 3.3 8.6 5.1 11.2 9.4 3.0 19.8 93.4 3.9 0.9 8.9 38.7 5.6 14.0 11.4 4.6 1.9 14.2 8.4 122.3 4.5 0.0 33.6 28.8 7.1 23.6 38.9 5.4 106.8 49.5 12.6 8.2 69.9 42.3 7.0 20.9 33.4 10.7 3.0 3.9 3.3 7.1 11.2 0.0 9.7 12.5 15.0 5.5 11.6 8.4 3.4 10.4 5.1 4.1 4.5 KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43781257 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 130.8" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 231.1;Syncytiotrophoblasts: 763.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.7;WM-115: 258.6" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 17: WM-115 - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA013367: , HPA053841: AB_2682278, HPA059622: AB_2684085" "unprognostic (1.23e-2)" "unprognostic (3.22e-2)" "unprognostic (4.29e-1)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.98e-2)" "unprognostic (7.33e-2)" "unprognostic (1.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (9.96e-3)" "prognostic unfavorable (1.05e-14)" "unprognostic (3.70e-2)" "unprognostic (2.17e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.75e-4)" 3.6 0.7 1.7 11.8 1.9 18.3 12.4 1.3 1.8 11.8 1.4 18.5 6.4 1.6 1.8 6.5 5.8 3.5 1.1 1.5 1.6 1.4 0.8 7.3 12.5 1.6 1.6 0.6 1.0 0.0 0.7 14.3 1.7 28.6 6.2 0.2 130.8 7.5 0.4 29.1 26.0 0.7 1.9 20.5 35.1 2.7 2.0 5.0 2.1 0.2 9.2 18.2 6.5 2.3 22.4 35.2 0.1 0.2 0.0 2.2 55.0 0.8 1.7 0.7 0.1 0.5 85.7 6.7 9.8 0.9 9.1 13.6 0.0 28.8 1.7 40.9 0.0 29.8 48.6 0.5 0.0 0.3 0.3 0.0 2.9 1.3 6.6 52.7 0.0 0.3 2.6 2.3 0.3 18.7 4.8 17.9 0.2 43.1 42.4 16.8 0.7 21.0 13.0 55.3 0.2 0.1 62.2 70.1 32.6 1.7 0.3 15.1 1.5 12.6 75.9 0.4 45.3 0.1 1.4 2.6 45.9 5.1 258.6 5.8 21.1 0.0 0.5 35.3 0.7 37.3 10.4 5.0 30.7 21.6 6.6 6.3 1.1 0.0 20.1 0.9 15.2 11.2 1.7 1.9 1.3 1.8 1.5 1.6 1.6 1.6 1.7 1.9 2.0 2.3 1.6 0.0 1.9 1.3 24.7 2.8 45.7 79.5 3.4 0.2 69.7 56.6 0.4 7.2 18.4 1.8 4.2 231.1 4.1 22.0 0.0 5.9 1.2 1.7 0.2 4.0 0.0 32.4 1.5 3.9 14.1 2.3 57.1 4.2 0.0 0.0 0.4 0.0 43.7 0.0 1.1 8.9 2.0 7.2 78.2 0.3 0.0 23.3 21.4 1.0 2.5 0.1 1.0 0.5 0.8 63.8 22.3 0.0 22.4 63.5 1.0 0.1 2.2 0.5 0.0 0.3 1.4 0.4 1.4 2.1 2.3 763.3 9.5 0.0 51.1 65.6 KLF1 EKLF ENSG00000105610 "Kruppel like factor 1" Q13351 19 12884422-12887201 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "bone marrow: 41.2" "Cell type enriched" "Detected in some" 199 "Erythroid cells: 519.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 8 "monocytes: 1.9" "Group enriched" "Detected in some" 29 "HEL: 61.6;K-562: 150.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA051850 Enhanced Supported Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "HPA051850: AB_2616460" "unprognostic (1.17e-1)" "unprognostic (1.38e-4)" "unprognostic (2.96e-1)" "unprognostic (1.17e-3)" "unprognostic (7.13e-2)" "unprognostic (3.90e-4)" "unprognostic (3.25e-2)" "unprognostic (3.19e-2)" "unprognostic (1.97e-1)" "unprognostic (1.08e-2)" "unprognostic (6.51e-2)" "unprognostic (7.71e-2)" "unprognostic (2.69e-3)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" "unprognostic (3.76e-1)" "unprognostic (2.44e-1)" 0.0 0.0 0.1 0.0 0.1 41.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.4 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 2.8 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 61.6 0.0 0.0 0.0 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 150.5 0.0 0.0 0.2 0.3 0.4 0.7 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.4 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 3.6 0.0 0.0 0.6 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.6 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 519.2 0.0 0.0 0.9 0.7 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.1 0.0 0.1 0.1 KLKB1 KLK3 ENSG00000164344 "Kallikrein B1" P03952 4 186208979-186258471 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Inflammatory response" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "liver: 328.4" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 280.5" "Cancer enriched" "Detected in some" 17 "liver cancer: 27.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 3.1;SCLC-21H: 2.1;U-937: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 28900000000 5300000000 "Cluster 62: Liver - Hemostasis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (4.80e-2)" "unprognostic (4.53e-3)" "unprognostic (4.36e-2)" "unprognostic (4.17e-2)" "unprognostic (5.93e-2)" "unprognostic (1.90e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-1)" "unprognostic (8.14e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-2)" "unprognostic (1.15e-1)" "unprognostic (1.45e-2)" "unprognostic (6.01e-2)" "unprognostic (7.30e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" 0.6 1.8 5.9 0.3 6.5 0.0 0.6 6.0 7.6 1.4 9.3 2.3 2.8 0.6 1.0 0.4 1.3 2.5 2.6 6.3 6.2 7.7 328.4 1.0 0.7 7.0 6.5 0.7 4.8 1.0 3.6 0.2 6.4 1.7 1.4 13.1 0.7 0.6 2.4 0.3 2.6 0.6 6.1 2.4 0.8 2.0 6.0 0.4 1.9 1.8 0.4 1.5 0.9 6.3 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.1 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.5 6.0 7.6 6.3 6.2 7.0 6.5 6.4 6.1 6.0 6.3 0.1 0.0 0.0 48.3 0.7 0.0 0.1 0.2 0.6 5.1 0.3 0.5 4.3 14.3 0.1 1.8 16.7 0.0 0.5 0.6 0.0 1.8 2.8 0.6 0.2 1.0 3.0 2.7 10.2 0.5 0.0 0.4 0.0 0.4 0.0 0.2 5.7 280.5 0.2 0.0 15.6 0.4 0.0 4.4 0.0 2.2 0.6 0.3 0.0 6.5 0.1 10.6 2.1 8.0 7.7 0.4 1.4 0.0 0.1 0.0 2.6 1.6 1.1 5.1 0.0 0.6 0.3 1.3 1.3 0.1 0.0 0.0 0.6 0.1 0.7 0.1 LBR "DHCR14B, TDRD18" ENSG00000143815 "Lamin B receptor" Q14739 1 225401502-225428925 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "DNA-binding, Oxidoreductase, Receptor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 248.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062236 Enhanced Supported "Nuclear membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear membrane" "HPA062236: AB_2684721" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (2.14e-3)" "unprognostic (1.32e-2)" "unprognostic (7.96e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (7.30e-4)" "unprognostic (3.60e-2)" "unprognostic (1.11e-2)" "unprognostic (3.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (6.42e-2)" "unprognostic (2.08e-1)" "unprognostic (5.45e-1)" "unprognostic (8.32e-2)" "unprognostic (2.78e-1)" 28.6 9.1 8.8 53.2 9.7 95.7 17.1 9.3 11.9 27.3 9.2 61.4 40.7 47.0 44.4 29.7 31.8 21.7 10.0 8.5 10.1 19.4 47.3 19.2 81.6 12.0 9.8 19.4 16.9 5.6 6.5 27.6 11.2 23.8 46.2 5.3 11.1 36.7 9.8 13.8 39.9 41.4 10.2 41.5 28.2 20.5 9.5 105.5 11.8 12.8 70.7 32.3 23.0 13.1 122.2 42.0 154.9 69.3 64.8 39.7 77.3 31.2 39.2 65.0 69.0 87.2 207.2 248.4 66.6 32.8 38.6 88.8 114.2 32.9 98.5 142.2 107.1 61.4 40.4 81.5 39.9 274.7 105.5 34.3 21.3 58.9 52.0 33.1 82.9 117.4 189.6 164.6 44.4 16.3 254.9 156.6 140.6 121.8 14.2 164.9 141.4 234.0 75.6 52.7 40.6 53.4 52.7 39.6 26.6 68.2 53.3 181.0 50.5 17.6 91.7 49.3 115.9 56.6 83.0 274.5 24.3 120.5 61.2 83.6 44.3 67.3 43.6 31.6 50.9 39.0 43.5 48.8 38.4 39.5 42.4 52.9 211.4 41.3 25.2 21.5 61.9 69.8 8.8 9.7 9.3 11.9 8.5 10.1 12.0 9.8 11.2 10.2 9.5 13.1 98.1 28.9 36.4 13.4 86.4 27.0 33.4 17.3 21.6 4.5 11.9 11.0 8.5 48.6 34.4 31.3 6.2 40.5 98.3 33.4 5.9 23.6 1.2 31.5 31.0 53.1 27.0 248.9 10.5 19.8 23.9 29.0 29.0 53.9 10.1 24.0 48.5 73.6 44.4 11.8 14.3 43.0 12.2 88.5 18.1 3.4 33.8 71.7 26.6 19.7 56.0 11.6 82.4 37.2 34.1 20.6 24.6 32.4 74.0 32.9 19.3 26.0 26.0 10.4 39.5 13.9 46.6 21.0 26.7 68.4 35.5 11.1 81.3 13.2 73.8 36.7 LMAN1 "ERGIC-53, ERGIC53, F5F8D, FMFD1, gp58, MCFD1, MR60" ENSG00000074695 "Lectin, mannose binding 1" P49257 18 59327823-59359265 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 502.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002320, CAB037163" Supported Supported "Endoplasmic reticulum,Vesicles" NA NA 18000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Endoplasmic reticulum" "CAB037163: AB_532237, HPA002320: AB_1079256" "unprognostic (5.64e-2)" "unprognostic (8.96e-3)" "unprognostic (4.20e-3)" "unprognostic (1.61e-1)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (1.65e-1)" "unprognostic (5.40e-3)" "unprognostic (1.16e-1)" "unprognostic (2.03e-1)" "unprognostic (2.40e-2)" "unprognostic (1.06e-1)" "unprognostic (5.79e-2)" "unprognostic (4.28e-2)" "unprognostic (5.37e-3)" "unprognostic (7.05e-2)" "unprognostic (3.71e-3)" 36.0 43.3 14.8 39.4 16.4 21.7 43.8 16.9 19.4 66.0 20.1 34.1 45.7 46.1 52.9 31.1 48.8 31.9 42.6 13.8 19.4 64.5 181.1 33.6 28.4 17.1 16.0 43.3 53.1 74.3 32.7 54.8 17.4 58.4 39.3 40.0 69.0 43.7 33.3 20.3 49.1 37.7 16.2 27.4 59.3 21.2 16.0 32.1 86.5 41.1 34.8 40.1 21.2 20.4 90.6 52.7 55.1 46.4 125.6 215.6 110.7 159.6 227.9 105.7 140.5 52.7 85.2 16.0 110.7 191.0 75.7 108.1 79.0 90.5 191.0 61.7 50.4 52.5 65.4 109.5 148.9 183.6 77.0 144.7 106.8 102.5 208.1 198.1 108.1 54.3 89.7 173.6 104.2 24.5 53.5 37.9 37.8 45.8 64.5 60.0 100.1 176.0 58.9 67.6 37.5 40.9 80.6 78.0 91.6 76.8 57.8 70.8 89.8 170.5 59.9 55.2 94.0 131.6 71.3 76.2 179.1 96.0 142.6 6.0 2.5 0.7 7.3 3.7 10.0 7.1 7.9 7.7 3.5 5.1 7.5 7.7 0.3 10.0 2.1 8.8 9.6 4.0 14.8 16.4 16.9 19.4 13.8 19.4 17.1 16.0 17.4 16.2 16.0 20.4 120.0 102.5 97.1 15.0 104.0 69.8 120.3 213.5 84.8 39.2 104.5 97.2 134.6 71.4 171.2 80.9 106.3 149.3 86.7 32.8 21.5 130.6 28.1 117.5 203.7 97.7 51.6 49.6 17.2 84.6 304.8 162.4 106.0 200.7 33.6 96.9 75.0 394.0 80.2 58.9 22.1 181.4 107.8 41.9 40.1 10.3 110.6 52.5 67.6 22.5 53.5 76.8 54.6 20.1 33.5 71.6 45.5 85.4 502.1 214.1 95.5 75.6 164.7 66.7 65.7 95.4 142.3 47.2 65.1 80.7 57.0 231.2 69.5 149.6 89.7 129.5 MAD2L2 "FANCV, MAD2B, POLZ2, REV7" ENSG00000116670 "Mitotic arrest deficient 2 like 2" Q9UI95 1 11674480-11691650 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 148.1;Late spermatids: 522.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008110, HPA024176, HPA024612" Approved Supported Nucleoli,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" Cytosol Nucleoli "CAB008110: AB_217976, HPA024176: AB_2671467, HPA024612: " "unprognostic (1.26e-2)" "unprognostic (2.55e-1)" "unprognostic (2.43e-1)" "unprognostic (3.27e-1)" "unprognostic (2.41e-1)" "unprognostic (6.84e-2)" "unprognostic (3.04e-3)" "unprognostic (1.48e-1)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (4.60e-2)" "unprognostic (1.24e-1)" "unprognostic (9.09e-3)" "unprognostic (1.54e-1)" "unprognostic (9.27e-2)" "unprognostic (8.43e-2)" "unprognostic (2.36e-1)" 25.6 19.5 30.3 22.2 32.0 59.8 25.2 33.2 35.9 23.5 27.6 24.6 11.6 19.3 15.0 14.6 20.4 13.4 26.5 30.2 33.1 37.7 49.8 29.6 27.7 34.9 30.2 21.7 39.9 13.3 22.7 10.6 31.7 22.3 7.5 5.0 28.6 11.2 49.3 23.5 17.1 15.5 31.6 25.2 28.8 64.3 35.3 55.1 15.4 31.5 26.1 23.1 17.8 35.9 62.8 57.2 90.8 106.8 28.6 55.1 37.3 56.5 64.8 110.4 97.8 75.2 59.2 87.6 67.6 58.1 64.4 27.4 115.1 60.1 60.5 133.3 129.6 40.1 87.5 93.4 50.2 80.5 62.7 36.1 60.7 81.0 68.9 41.6 51.4 116.7 165.6 138.3 55.5 94.6 365.6 381.3 235.1 25.9 91.2 245.6 100.2 109.6 40.8 13.5 167.8 118.1 93.6 36.5 168.1 61.2 52.6 172.1 26.8 90.7 114.1 85.6 81.8 109.5 82.0 233.7 67.2 281.5 71.8 45.3 85.2 42.8 82.1 97.3 66.8 58.5 55.4 64.8 100.8 43.8 37.0 54.9 36.7 43.3 86.8 139.1 69.9 92.0 30.3 32.0 33.2 35.9 30.2 33.1 34.9 30.2 31.7 31.6 35.3 35.9 24.8 0.0 5.0 4.2 26.1 38.6 26.5 35.7 18.8 5.7 26.9 26.9 15.9 11.5 14.1 14.7 4.2 18.2 49.6 3.7 50.9 40.8 148.1 8.4 21.6 28.2 34.0 69.5 1.7 76.6 50.7 30.6 12.2 11.4 14.0 17.3 29.6 59.1 41.7 11.8 2.3 10.6 54.9 36.4 88.1 522.5 31.1 32.5 48.0 1.9 82.6 10.8 53.5 4.0 5.5 40.7 4.5 17.0 42.9 35.8 4.5 29.6 6.0 3.5 39.5 25.1 26.5 76.0 40.6 14.3 34.7 8.3 37.7 18.8 8.6 17.6 MASTL "FLJ14813, Gwl, THC2" ENSG00000120539 "Microtubule associated serine/threonine kinase like" Q96GX5 10 27154824-27187953 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027175, HPA054273" Approved Enhanced Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027175: AB_1853591, HPA054273: AB_2682433" "unprognostic (4.10e-2)" "unprognostic (6.89e-2)" "unprognostic (1.22e-2)" "unprognostic (3.14e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.52e-6)" "unprognostic (2.19e-2)" "unprognostic (4.00e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.81e-5)" "unprognostic (3.78e-2)" "prognostic unfavorable (1.71e-6)" "unprognostic (1.55e-3)" "unprognostic (2.27e-1)" "unprognostic (2.66e-1)" "unprognostic (1.79e-1)" 5.0 3.9 1.7 6.2 1.9 18.7 5.3 2.3 2.3 3.8 2.1 4.1 4.4 3.9 4.5 5.9 3.0 3.9 2.5 1.9 2.0 3.9 4.9 4.0 8.9 2.0 2.0 3.4 3.3 6.0 3.1 6.5 2.1 3.1 5.2 2.7 4.1 3.0 2.3 6.0 4.3 4.5 1.6 4.6 4.7 6.5 2.0 10.4 4.7 2.2 7.1 4.5 4.3 2.3 29.4 22.0 43.8 15.5 6.2 9.1 25.4 43.3 18.0 68.4 83.8 26.7 27.2 22.4 16.1 18.4 33.5 26.8 27.9 16.0 48.2 20.2 26.5 26.9 14.5 15.5 3.8 10.4 19.8 5.6 7.5 41.6 7.9 9.0 14.7 18.2 21.1 49.9 41.5 17.9 34.8 11.2 32.0 15.9 8.9 22.2 71.9 18.9 17.4 10.6 19.2 26.8 26.0 17.6 19.1 28.1 17.2 21.4 12.6 17.0 36.3 44.0 37.4 5.9 10.3 34.7 18.3 31.1 14.8 0.2 1.8 1.7 0.7 1.7 1.1 1.1 0.9 0.7 1.0 1.6 0.9 0.8 2.3 1.0 1.8 1.1 1.6 0.8 1.7 1.9 2.3 2.3 1.9 2.0 2.0 2.0 2.1 1.6 2.0 2.3 4.3 6.4 7.8 2.6 7.4 11.0 4.9 4.4 4.0 1.7 4.2 4.8 3.0 2.8 7.0 1.8 0.0 8.6 10.1 7.0 0.0 4.0 3.0 9.7 5.3 4.6 4.2 7.8 4.3 2.5 24.9 7.3 6.1 17.9 12.7 6.9 2.5 2.5 5.8 3.3 4.3 3.7 4.1 7.8 19.3 1.7 3.1 11.3 0.0 3.7 5.1 1.8 3.1 3.5 4.9 4.4 2.9 2.6 7.1 5.0 2.8 1.9 4.0 1.0 0.0 3.8 5.3 14.9 14.1 10.9 9.9 6.2 11.6 5.4 4.5 6.6 MCFD2 "F5F8D, LMAN1IP, SDNSF" ENSG00000180398 "Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit" Q8NI22 2 46901870-46941855 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 253.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022410, HPA034593" Supported "Intracellular and membrane" NA NA 1200000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "CAB022410: , HPA034593: AB_2674239" "unprognostic (1.16e-2)" "unprognostic (5.71e-3)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" "unprognostic (2.50e-1)" "unprognostic (2.87e-2)" "unprognostic (3.98e-2)" "unprognostic (3.10e-2)" "unprognostic (3.93e-2)" "unprognostic (8.32e-2)" "unprognostic (1.56e-3)" "unprognostic (1.82e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.64e-4)" 52.0 155.5 41.3 35.6 43.1 34.7 55.1 38.1 40.3 50.4 69.5 32.2 32.5 54.5 42.1 45.9 41.9 44.9 42.3 41.3 46.8 59.4 111.8 45.0 32.1 33.5 41.3 79.2 104.1 52.5 38.7 70.1 41.6 54.0 26.9 83.3 149.7 82.9 83.3 26.0 33.4 52.5 28.0 44.6 33.9 30.9 48.6 30.8 121.0 84.6 34.2 41.2 29.2 34.7 147.7 86.9 74.7 59.7 151.5 215.1 115.4 248.4 254.1 129.4 116.8 116.9 109.4 96.4 297.7 294.7 154.3 81.8 67.0 127.0 207.7 64.5 67.2 101.9 87.1 182.5 236.5 94.8 158.6 163.2 77.8 206.7 178.7 247.9 210.8 28.0 199.3 56.0 266.8 48.7 56.9 67.6 63.9 102.3 84.1 68.3 133.2 106.7 80.3 59.3 23.9 62.2 93.1 46.9 116.0 86.3 33.1 80.6 341.1 298.3 130.5 97.0 164.2 42.0 43.8 76.4 320.2 88.0 100.8 27.2 21.4 29.7 9.6 23.3 12.2 12.5 10.9 10.2 18.4 12.8 14.3 9.8 12.0 9.9 18.3 16.9 9.7 14.0 41.3 43.1 38.1 40.3 41.3 46.8 33.5 41.3 41.6 28.0 48.6 34.7 50.8 105.8 89.1 16.6 29.6 48.2 56.5 65.3 36.5 69.3 64.4 48.5 70.3 38.6 68.8 47.8 39.6 75.5 25.4 26.6 21.5 88.6 144.3 76.4 60.2 64.7 26.8 28.2 19.6 178.5 64.5 70.1 20.4 69.9 50.5 44.1 53.9 155.1 54.5 38.7 23.8 28.5 18.3 40.5 31.3 113.7 62.7 39.2 12.4 7.5 33.8 253.2 12.3 16.1 16.2 152.7 23.1 59.5 43.8 82.4 42.2 41.3 69.6 51.3 65.7 63.9 55.4 48.9 32.6 39.6 44.9 102.1 23.4 74.3 22.8 75.8 MPL "CD110, THPOR, TPOR" ENSG00000117400 "MPL proto-oncogene, thrombopoietin receptor" P40238 1 43337818-43354466 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Erythroid cells: 3.0;Excitatory neurons: 2.0;Oligodendrocytes: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enriched" "Detected in some" 57 "HEL: 77.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Low region specificity" "Detected in many" HPA007619 Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Nuclear membrane" "HPA007619: AB_1854080" "unprognostic (2.74e-1)" "unprognostic (6.56e-2)" "unprognostic (2.95e-1)" "unprognostic (8.71e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.22e-2)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (5.94e-4)" "unprognostic (1.51e-1)" "unprognostic (1.19e-4)" "unprognostic (2.39e-1)" "unprognostic (3.26e-1)" "unprognostic (1.03e-4)" "unprognostic (1.42e-1)" 0.6 0.4 0.8 0.2 1.7 1.8 0.4 0.8 1.3 0.3 0.1 0.3 0.3 0.7 1.2 0.5 0.8 0.3 1.0 0.6 1.2 0.4 0.4 0.6 0.2 1.2 1.0 2.9 0.8 0.4 0.0 0.3 1.1 0.9 0.4 1.5 0.4 0.7 0.6 0.5 0.2 0.7 0.7 0.4 0.5 1.2 1.1 0.1 0.9 0.3 0.1 0.2 0.0 2.8 0.4 0.7 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.3 0.1 0.3 0.1 0.0 0.6 0.0 0.2 0.0 0.4 0.1 77.4 1.2 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.5 0.1 0.1 0.2 0.0 0.2 0.7 0.6 0.4 0.2 0.6 0.1 0.2 0.2 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.2 1.4 0.1 0.1 0.3 0.1 1.8 0.8 1.7 0.8 1.3 0.6 1.2 1.2 1.0 1.1 0.7 1.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MYH9 "DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA" ENSG00000100345 "Myosin heavy chain 9" P35579 22 36281280-36387967 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Alport syndrome, Cancer-related genes, Cataract, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 1343.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001644, CAB015386, HPA064783" Enhanced Supported "Nuclear bodies,Plasma membrane,Actin filaments,Cytosol" No No 410000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments" "Nuclear bodies, Cytosol" "CAB015386: AB_784698, HPA001644: AB_1079439, HPA064783: AB_2732721" "unprognostic (1.38e-1)" "unprognostic (9.12e-2)" "unprognostic (4.21e-2)" "unprognostic (6.34e-2)" "unprognostic (1.49e-1)" "unprognostic (3.90e-2)" "unprognostic (9.56e-2)" "unprognostic (8.28e-2)" "unprognostic (5.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (9.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.62e-1)" "unprognostic (2.59e-2)" 295.9 95.5 42.3 181.1 42.1 245.9 231.5 40.6 54.7 181.2 65.5 192.6 107.0 356.4 39.3 153.8 182.2 134.5 161.1 50.8 39.4 140.7 101.6 286.2 161.7 52.7 51.7 121.1 160.3 55.0 52.6 166.5 48.1 131.8 89.8 9.7 177.2 98.4 84.0 160.6 163.5 174.1 48.8 232.5 135.8 38.2 52.1 125.1 141.2 46.3 104.1 168.8 166.8 48.2 612.2 277.0 86.2 74.2 156.8 195.1 437.3 398.4 507.5 554.6 413.2 302.1 170.3 156.9 230.1 666.1 265.0 412.7 125.2 779.4 559.6 356.1 120.9 302.6 294.3 259.9 481.1 346.9 463.8 233.0 234.7 751.9 626.4 540.3 461.8 113.2 67.3 205.8 448.9 161.9 124.4 204.0 51.7 171.1 169.2 233.3 267.3 146.7 314.5 581.5 129.6 53.0 559.7 217.0 251.6 218.5 162.4 177.1 1343.7 1222.6 370.3 237.5 731.5 135.2 114.7 129.0 463.2 172.3 363.1 72.6 25.2 64.7 32.4 19.8 28.4 13.4 23.5 26.4 17.2 11.9 18.3 20.4 41.2 9.0 26.5 8.0 26.3 54.5 42.3 42.1 40.6 54.7 50.8 39.4 52.7 51.7 48.1 48.8 52.1 48.2 303.9 118.6 87.1 12.7 108.4 144.0 182.4 123.1 72.8 2.6 90.5 89.4 62.6 80.1 89.7 92.0 2.1 87.0 151.7 359.8 7.9 309.4 35.8 89.7 121.6 258.7 73.8 51.9 42.5 245.8 193.1 82.9 123.8 194.7 93.1 117.1 132.8 102.8 100.4 82.4 6.7 131.0 59.0 119.6 124.2 37.4 68.0 168.8 85.4 61.8 196.6 11.9 137.0 7.5 33.3 344.6 186.8 211.4 125.9 184.4 159.8 27.5 51.5 5.3 203.8 39.9 275.2 6.9 10.4 133.6 135.1 46.4 213.2 141.3 139.5 134.3 NBEAL2 KIAA0540 ENSG00000160796 "Neurobeachin like 2" Q6ZNJ1 3 46979666-47009704 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.2" "Cell type enriched" "Detected in many" 4 "Gastric mucus-secreting cells: 144.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 4.4" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.4" "Cell line enhanced" "Detected in many" "HEL: 69.1;SK-BR-3: 64.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051969 Approved NA NA 31000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA051969: " "unprognostic (3.83e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-1)" "unprognostic (3.37e-2)" "unprognostic (5.99e-3)" "prognostic favorable (4.60e-4)" "unprognostic (1.71e-2)" "unprognostic (1.00e-1)" "unprognostic (4.17e-1)" "unprognostic (6.27e-2)" "unprognostic (5.29e-2)" "unprognostic (1.06e-3)" "unprognostic (3.75e-1)" "unprognostic (6.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.80e-1)" "unprognostic (1.34e-2)" 16.7 16.0 4.0 23.3 3.6 92.1 19.3 3.3 5.7 34.3 4.4 21.5 12.8 10.5 4.6 103.2 14.7 11.0 15.2 3.3 3.4 36.9 11.2 54.0 20.9 4.2 3.8 7.9 40.7 6.7 11.3 4.8 4.5 21.5 8.4 0.8 35.6 8.4 6.5 86.0 31.0 5.6 3.8 70.0 42.5 6.3 4.6 11.2 14.7 2.9 15.8 16.6 56.8 3.7 20.2 22.1 4.0 11.3 2.3 0.8 12.9 2.8 1.7 3.8 2.5 19.4 14.2 17.4 7.7 2.4 3.7 13.0 8.3 9.0 1.9 15.4 12.4 69.1 27.8 12.2 2.2 11.9 48.5 1.9 14.8 3.9 6.0 4.6 34.2 36.2 14.6 26.3 1.9 31.2 20.5 32.7 10.6 31.9 10.0 21.6 0.5 23.0 9.1 41.1 6.1 9.9 2.4 64.4 5.7 4.9 31.5 19.9 25.3 0.3 11.7 5.1 8.9 20.1 20.7 16.3 5.1 55.0 2.9 0.2 0.6 0.4 0.5 0.6 0.1 0.0 0.2 0.5 0.1 0.0 0.1 0.1 4.4 0.4 0.4 0.1 0.2 0.3 4.0 3.6 3.3 5.7 3.3 3.4 4.2 3.8 4.5 3.8 4.6 3.7 15.0 12.8 9.4 7.8 10.0 3.3 5.5 2.4 5.7 1.3 16.3 18.2 4.3 8.6 9.3 33.1 18.8 2.2 30.8 15.1 1.9 22.9 1.4 20.0 4.1 9.8 7.2 10.3 4.0 23.1 1.1 3.0 144.3 23.9 6.3 5.1 11.7 1.2 11.1 0.0 1.5 11.5 4.1 12.9 8.3 1.0 1.2 27.9 0.0 6.5 14.6 1.5 26.8 1.0 1.4 31.4 5.6 0.0 14.2 6.2 3.4 1.3 6.6 1.9 13.1 3.4 3.5 0.5 2.4 33.6 8.0 1.9 26.3 4.5 15.1 21.0 NRAS N-ras ENSG00000213281 "NRAS proto-oncogene, GTPase" P01111 1 114704469-114716771 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010157, HPA049830, CAB079912" Uncertain Supported "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010157: AB_632073, CAB079912: AB_2784586, HPA049830: AB_2680903" "unprognostic (4.75e-2)" "unprognostic (2.81e-1)" "unprognostic (1.09e-3)" "unprognostic (2.11e-2)" "unprognostic (8.59e-3)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-7)" "unprognostic (7.76e-3)" "unprognostic (1.57e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (6.60e-3)" "prognostic unfavorable (7.87e-4)" "unprognostic (2.68e-1)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (3.33e-2)" 19.0 9.1 10.3 25.7 11.2 58.5 18.0 11.5 12.3 12.5 8.6 27.8 21.5 12.4 7.8 20.7 10.3 17.2 8.3 10.2 12.2 20.9 24.9 18.5 30.4 12.3 12.1 9.6 11.4 9.0 4.3 28.3 12.3 11.4 26.6 6.6 10.9 7.1 7.7 19.8 22.5 14.1 11.7 18.6 21.8 9.6 11.4 39.0 16.1 7.8 29.7 22.2 8.6 13.4 93.7 24.9 65.2 24.9 26.4 56.3 46.5 43.5 48.4 79.5 89.0 50.4 33.9 70.4 56.3 58.9 55.4 26.0 88.2 70.6 113.4 96.5 34.2 47.8 34.5 60.2 52.3 120.0 71.0 51.1 56.1 91.5 66.2 25.0 102.8 54.6 77.3 78.5 71.0 248.9 83.5 46.4 111.0 30.2 17.9 62.9 116.0 44.1 70.6 49.5 39.4 59.0 44.7 36.4 107.1 75.4 31.9 96.2 79.2 43.3 82.2 81.5 90.3 137.7 101.6 81.6 86.4 64.6 159.0 38.7 12.8 12.6 11.7 19.2 10.5 12.8 9.3 11.6 12.6 10.5 9.9 12.9 3.4 15.5 17.6 9.6 13.4 13.1 10.3 11.2 11.5 12.3 10.2 12.2 12.3 12.1 12.3 11.7 11.4 13.4 22.7 16.0 16.5 8.1 25.9 30.7 31.2 23.1 15.4 5.2 18.5 13.6 5.6 18.6 19.3 22.0 8.4 22.4 27.7 49.2 13.7 34.1 3.9 22.9 24.7 29.2 24.6 31.6 5.8 31.5 50.4 16.1 29.0 38.0 31.1 22.2 33.2 29.7 49.2 5.0 5.2 28.1 30.5 44.9 30.7 5.9 8.1 30.4 23.2 9.4 41.6 7.8 22.6 5.0 8.1 51.4 32.9 6.4 39.6 30.6 28.1 39.4 23.1 3.3 6.6 12.8 15.3 7.3 15.4 24.6 36.2 31.2 21.9 13.8 28.8 40.2 NT5C3A "cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1" ENSG00000122643 "5'-nucleotidase, cytosolic IIIA" Q9H0P0 7 33014114-33062797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 87.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 191.0;Paneth cells: 186.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010520, HPA010630, HPA029058" Uncertain Supported "Nucleoplasm,Nuclear bodies,Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 10000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Endoplasmic reticulum, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA010520: , HPA010630: AB_2668319, HPA029058: AB_10601380" "unprognostic (7.50e-2)" "unprognostic (3.10e-1)" "unprognostic (1.14e-1)" "unprognostic (2.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (3.25e-2)" "unprognostic (3.12e-2)" "unprognostic (2.82e-3)" "unprognostic (2.08e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (9.37e-2)" "unprognostic (2.05e-1)" "unprognostic (2.12e-3)" "unprognostic (3.43e-3)" 12.4 14.3 11.4 26.1 11.4 32.6 21.3 15.2 15.6 12.6 10.8 51.9 40.0 16.9 14.3 18.6 15.9 23.4 16.6 11.5 11.5 22.4 11.8 17.6 30.8 11.1 11.8 13.4 21.4 9.7 7.5 16.3 11.5 12.3 51.0 20.4 9.7 10.0 87.4 28.7 37.3 13.2 12.7 22.9 27.0 9.5 12.0 22.5 17.1 51.0 45.8 23.8 14.4 13.1 42.2 27.6 25.2 29.6 21.2 16.1 20.3 44.8 30.5 29.2 38.9 19.9 115.1 100.4 27.7 29.6 48.3 63.8 28.3 30.8 40.4 16.2 36.2 54.7 36.5 28.7 23.3 55.6 36.9 21.7 23.8 35.9 63.0 16.4 22.2 33.2 43.3 24.8 37.3 29.9 25.0 87.8 27.8 47.1 31.2 25.9 22.9 60.0 87.8 39.8 28.1 37.0 31.1 52.4 66.6 24.5 35.2 33.5 19.8 25.1 20.9 42.6 55.7 50.6 69.0 54.8 20.6 34.9 42.5 112.5 25.9 82.5 26.6 32.7 30.6 64.0 34.2 30.8 22.1 63.6 34.5 29.1 103.8 28.2 39.2 20.6 56.2 37.9 11.4 11.4 15.2 15.6 11.5 11.5 11.1 11.8 11.5 12.7 12.0 13.1 39.1 22.4 13.7 30.7 85.1 46.8 40.9 85.3 47.8 23.9 22.6 18.9 16.9 32.9 40.4 16.5 41.7 36.9 42.5 191.0 29.4 34.4 5.7 40.9 21.0 40.8 119.6 127.1 45.3 79.0 31.6 35.2 42.8 21.4 17.7 38.3 30.0 18.9 25.0 1.7 49.4 98.9 40.7 31.2 23.5 5.0 33.8 111.4 26.6 29.0 37.0 23.4 55.6 48.2 52.4 48.3 186.6 22.2 43.8 45.7 91.8 84.8 53.7 27.1 13.1 30.7 24.9 46.4 24.0 35.5 38.9 28.3 53.7 23.3 71.0 65.9 P2RY12 "HORK3, P2Y12, SP1999" ENSG00000169313 "Purinergic receptor P2Y12" Q9H244 3 151336843-151384753 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.8;lymphoid tissue: 9.8" "Cell type enriched" "Detected in some" 27 "Microglial cells: 421.6" "Cancer enriched" "Detected in many" 14 "glioma: 17.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 8.3" "Group enriched" "Detected in many" 11 "dendritic cells: 3.2;monocytes: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013796, HPA014518" Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 68: Oligodendrocytes - Mixed function" "HPA013796: AB_1854884, HPA014518: AB_2669027" "unprognostic (2.39e-2)" "unprognostic (1.60e-3)" "unprognostic (5.93e-2)" "unprognostic (1.77e-1)" "unprognostic (2.41e-2)" "unprognostic (2.52e-2)" "unprognostic (8.09e-2)" "unprognostic (1.72e-3)" "unprognostic (6.46e-2)" "unprognostic (8.64e-4)" "unprognostic (4.84e-2)" "unprognostic (5.96e-2)" "unprognostic (2.03e-1)" "unprognostic (8.92e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-2)" "unprognostic (4.04e-1)" 8.6 4.0 4.8 1.9 5.1 0.5 3.7 5.1 6.1 1.3 2.4 1.6 1.2 0.7 0.6 1.2 2.5 2.2 1.3 5.7 6.9 0.6 2.5 2.5 9.8 10.2 8.1 1.6 0.8 1.6 0.3 2.3 11.8 0.9 1.4 0.3 2.9 2.0 0.1 0.4 2.8 1.6 11.5 5.5 1.1 0.2 8.5 0.9 0.5 0.6 8.7 1.1 0.4 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 8.3 0.0 0.3 0.0 0.0 3.2 0.5 0.0 0.0 0.3 0.0 2.2 0.3 0.0 1.3 4.8 5.1 5.1 6.1 5.7 6.9 10.2 8.1 11.8 11.5 8.5 13.8 0.2 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 2.1 0.0 0.0 2.6 0.0 0.0 0.0 3.1 0.0 421.6 0.7 0.4 0.0 15.6 4.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 PALB2 "FANCN, FLJ21816" ENSG00000083093 "Partner and localizer of BRCA2" Q86YC2 16 23603160-23641310 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB014895, HPA057000" Approved Supported Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB014895: , HPA057000: AB_2683307" "unprognostic (1.11e-1)" "unprognostic (5.67e-3)" "prognostic favorable (2.83e-5)" "unprognostic (1.43e-2)" "unprognostic (6.22e-2)" "unprognostic (1.61e-2)" "unprognostic (2.00e-3)" "unprognostic (5.18e-2)" "unprognostic (2.46e-2)" "unprognostic (2.00e-2)" "prognostic unfavorable (2.35e-5)" "unprognostic (2.05e-2)" "unprognostic (1.04e-2)" "unprognostic (2.72e-1)" "unprognostic (1.25e-1)" "unprognostic (7.20e-2)" "unprognostic (3.21e-1)" 5.8 5.6 6.2 4.4 6.5 3.5 6.4 9.8 10.7 7.1 6.2 6.1 6.5 5.6 5.6 10.1 5.4 3.3 4.7 6.2 6.1 7.9 9.9 4.8 6.3 6.0 6.2 6.2 6.0 5.8 5.1 3.8 6.2 5.3 5.3 8.6 6.0 4.0 5.4 9.0 7.0 4.0 5.7 7.8 5.7 9.8 6.6 6.4 5.3 4.8 6.9 6.6 7.2 7.0 17.3 13.1 15.4 10.8 12.6 9.4 13.9 12.0 18.4 19.7 23.6 11.2 17.3 18.2 8.7 8.6 15.0 15.2 13.9 19.8 23.4 10.8 8.1 11.2 18.2 31.8 11.7 20.5 17.3 11.2 20.3 18.7 20.7 10.9 10.6 17.1 23.4 9.4 17.2 17.4 21.2 21.3 34.3 12.5 7.6 24.2 18.9 24.7 15.2 15.2 11.2 11.3 12.5 13.5 16.7 13.4 12.9 13.9 7.7 23.1 8.7 11.2 13.2 11.2 19.0 18.3 15.4 14.8 14.3 6.4 1.8 1.8 2.1 2.3 2.6 1.8 2.4 2.7 2.0 1.4 2.6 2.1 0.1 2.1 4.5 1.5 1.7 1.1 6.2 6.5 9.8 10.7 6.2 6.1 6.0 6.2 6.2 5.7 6.6 7.0 4.7 12.8 4.2 8.5 5.1 0.9 3.5 5.4 2.2 4.8 4.0 3.7 4.8 2.8 8.2 3.7 4.2 2.9 3.8 2.4 3.9 5.8 6.8 2.3 5.1 4.8 1.2 4.6 7.4 5.0 2.0 4.4 4.1 2.6 5.1 7.7 3.3 4.7 3.7 1.7 8.0 3.4 2.0 5.0 1.5 3.6 4.7 5.1 1.8 5.6 8.4 4.8 5.2 7.1 5.9 8.6 2.5 6.4 4.2 5.3 4.6 5.4 8.3 7.5 6.6 4.7 3.0 30.0 17.7 5.4 2.7 1.2 3.7 6.9 4.8 4.1 PGK1 ENSG00000102144 "Phosphoglycerate kinase 1" P00558 X 77910739-78129295 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 1126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010065, HPA045385, HPA073644, HPA073656" Approved NA NA 170000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB010065: AB_628116, HPA045385: AB_2679306, HPA073644: AB_2732231, HPA073656: AB_2732235" "prognostic unfavorable (7.05e-8)" "prognostic unfavorable (2.69e-5)" "unprognostic (1.21e-1)" "unprognostic (8.30e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.65e-6)" "prognostic unfavorable (2.74e-4)" "unprognostic (1.13e-2)" "unprognostic (1.27e-1)" "unprognostic (6.66e-2)" "prognostic unfavorable (8.34e-4)" "unprognostic (5.66e-2)" "unprognostic (2.99e-1)" "unprognostic (8.99e-3)" "unprognostic (3.58e-1)" "unprognostic (2.90e-2)" "unprognostic (6.57e-2)" 120.7 141.8 87.3 149.0 94.1 252.8 89.1 103.2 119.0 100.2 117.2 127.4 123.4 72.3 73.0 154.1 79.3 110.1 247.4 92.7 109.2 233.5 143.8 117.1 139.0 104.8 95.1 61.9 61.1 188.8 30.0 138.6 109.5 92.8 143.1 298.8 93.2 101.8 452.0 92.6 119.1 116.7 102.4 97.2 86.1 29.2 111.1 158.3 105.6 266.7 189.6 148.4 49.4 101.3 943.0 426.7 139.7 283.8 236.1 190.0 331.3 469.2 324.0 402.9 670.0 390.2 287.7 373.9 473.7 326.5 479.5 397.6 624.8 729.3 800.7 229.8 246.6 290.3 657.8 341.8 258.0 671.8 309.2 238.5 302.2 366.7 192.7 646.1 418.8 361.9 308.5 553.4 557.4 371.2 593.5 506.0 433.3 628.5 800.7 421.8 374.4 1157.0 423.8 385.4 208.0 286.6 486.3 409.0 422.9 352.6 214.8 347.9 340.2 428.1 294.3 433.4 329.0 609.5 1221.7 391.5 1207.0 750.5 286.6 170.6 360.2 321.1 121.9 382.0 135.9 128.4 144.3 132.9 333.7 101.2 130.9 140.7 281.9 140.3 527.0 130.2 168.4 606.0 87.3 94.1 103.2 119.0 92.7 109.2 104.8 95.1 109.5 102.4 111.1 101.3 166.3 150.6 168.6 20.2 174.8 144.3 272.2 1126.6 122.3 211.3 72.4 67.2 480.4 140.2 436.9 174.7 77.2 298.4 200.6 196.5 471.6 715.8 19.3 123.7 112.4 182.3 102.4 95.9 32.5 236.4 746.4 131.3 95.3 145.1 195.5 98.1 139.6 200.2 499.0 309.6 37.0 164.3 518.8 298.4 188.8 12.1 94.8 310.4 167.2 25.3 499.3 245.7 131.8 20.1 21.9 510.2 149.9 127.2 214.8 118.3 221.5 566.0 235.6 188.8 124.9 84.0 191.8 8.8 57.4 138.4 119.1 349.6 251.9 278.7 203.5 225.8 PIEZO1 "FAM38A, KIAA0233" ENSG00000103335 "Piezo type mechanosensitive ion channel component 1" Q92508 16 88715338-88785220 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Pancreatic endocrine cells: 85.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 270.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA047185 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA047185: AB_2679973" "unprognostic (1.76e-1)" "prognostic unfavorable (2.37e-4)" "unprognostic (1.77e-1)" "unprognostic (1.12e-2)" "unprognostic (4.08e-2)" "unprognostic (2.34e-2)" "unprognostic (2.64e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (4.39e-2)" "prognostic unfavorable (3.78e-4)" "unprognostic (3.51e-2)" "unprognostic (3.05e-2)" "prognostic unfavorable (8.89e-7)" "unprognostic (2.04e-1)" "unprognostic (3.59e-2)" "unprognostic (2.86e-2)" "unprognostic (3.74e-1)" 79.0 26.4 15.2 20.5 16.0 29.8 65.1 16.5 19.0 30.7 10.4 86.7 7.7 40.4 0.5 48.4 38.1 9.0 29.4 12.9 13.8 57.2 48.2 67.2 14.8 25.0 17.6 15.8 21.9 5.2 6.8 18.6 22.5 49.4 4.8 1.7 33.3 11.2 6.8 48.8 41.1 14.3 17.6 55.2 38.0 5.2 17.4 7.2 32.4 4.3 5.9 65.3 40.4 21.2 42.0 42.1 6.5 31.3 27.6 30.0 155.2 99.9 43.9 36.1 14.0 61.3 68.5 34.2 68.2 48.4 18.0 88.4 13.9 36.0 7.3 33.8 56.0 58.3 77.9 49.4 41.6 26.4 9.3 24.6 19.4 28.3 23.3 21.3 43.9 56.1 80.4 42.8 21.2 270.1 32.7 91.2 14.7 19.7 25.7 77.7 9.3 86.9 16.4 61.1 12.8 3.4 130.5 68.0 17.8 6.5 93.0 76.5 120.1 86.0 49.6 58.4 51.6 8.7 21.1 21.2 67.9 46.5 52.2 1.8 5.0 3.3 8.1 9.7 7.8 2.3 6.0 5.5 9.7 3.1 1.0 2.5 0.1 1.0 13.1 1.7 5.0 3.9 15.2 16.0 16.5 19.0 12.9 13.8 25.0 17.6 22.5 17.6 17.4 21.2 69.1 73.7 19.8 27.1 14.3 19.1 12.9 27.6 5.2 2.2 23.5 16.3 5.0 10.0 17.1 58.8 16.7 6.7 16.8 19.3 0.0 37.3 1.6 6.2 15.4 45.0 21.0 12.6 0.4 21.7 30.5 13.7 25.0 9.9 8.8 0.7 55.3 22.0 23.6 3.3 0.5 29.5 10.2 16.8 19.0 1.0 5.6 21.8 16.0 21.5 15.6 1.5 3.1 16.6 5.0 85.9 18.0 2.6 30.8 48.3 8.1 5.5 9.7 4.1 0.0 30.3 9.0 0.3 2.0 18.9 15.9 5.1 21.6 5.6 12.0 21.8 PIGA GPI3 ENSG00000165195 "Phosphatidylinositol glycan anchor biosynthesis class A" P37287 X 15319452-15335554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 83.5;Suprabasal keratinocytes: 55.0;Urothelial cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 22.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001174 Approved NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "HPA001174: AB_2666220" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.92e-2)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (2.99e-3)" "unprognostic (2.24e-2)" "unprognostic (7.37e-3)" "unprognostic (3.93e-3)" "prognostic unfavorable (7.64e-4)" "unprognostic (1.85e-3)" "unprognostic (5.97e-3)" "unprognostic (2.24e-1)" "unprognostic (3.94e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-2)" 2.1 2.9 2.2 2.9 2.7 9.2 3.1 2.0 3.6 2.8 0.8 3.7 1.9 3.0 3.5 5.1 2.8 3.7 2.0 1.6 1.8 3.8 4.5 6.7 3.5 2.8 2.7 2.4 4.0 3.3 0.6 3.6 2.2 2.7 3.7 4.5 4.6 1.7 1.3 1.4 2.4 2.5 2.2 2.0 2.8 2.6 2.3 4.0 4.4 1.3 4.7 10.3 1.9 5.8 14.5 8.3 9.1 5.0 2.6 2.8 7.0 3.7 5.7 7.4 7.3 9.2 6.5 6.6 2.9 2.9 9.0 5.8 14.3 11.4 12.6 6.1 9.5 5.5 11.0 5.8 4.5 8.8 2.9 3.3 8.1 10.0 16.0 2.4 5.0 5.2 6.4 7.0 5.1 9.2 9.0 3.4 4.7 5.5 8.2 3.0 12.4 10.7 5.6 9.4 6.2 9.4 6.9 6.8 14.4 8.7 6.6 7.4 4.2 6.2 2.4 14.0 7.3 5.4 7.2 9.9 9.4 5.6 7.9 22.9 3.8 4.3 2.6 6.3 3.7 3.0 4.1 2.6 3.9 2.1 3.8 2.9 5.2 1.8 8.6 2.6 4.1 2.7 2.2 2.7 2.0 3.6 1.6 1.8 2.8 2.7 2.2 2.2 2.3 5.8 6.4 19.2 83.5 6.8 7.2 29.6 41.9 10.6 13.6 3.5 13.2 10.5 6.9 5.7 20.1 3.7 0.0 6.3 7.4 8.4 11.7 7.6 5.4 30.8 9.8 7.9 10.7 9.3 2.2 5.8 10.2 12.7 17.9 45.6 33.6 3.0 3.6 4.4 8.8 3.3 2.0 5.0 2.0 8.4 43.4 4.4 3.1 18.1 28.4 2.8 3.6 4.2 4.1 1.0 7.7 8.3 5.1 3.0 5.5 32.0 2.1 6.6 19.8 3.0 13.1 10.6 16.3 2.7 3.7 35.5 55.0 28.0 11.7 2.9 6.0 62.2 PLG ENSG00000122194 Plasminogen P00747 6 160702238-160754097 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 2666.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 1772.7" "Cancer enriched" "Detected in some" 84 "liver cancer: 180.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000668, CAB016678, HPA021602, HPA048823" Supported "Secreted to blood" NA NA 140000000000 45000000000 "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" "CAB000668: , CAB016678: AB_1621208, HPA021602: AB_1855453, HPA048823: AB_2680532" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.44e-1)" "unprognostic (8.54e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (6.28e-2)" "unprognostic (7.25e-2)" "prognostic favorable (4.22e-4)" "unprognostic (3.97e-3)" "unprognostic (5.21e-2)" "unprognostic (2.33e-2)" 0.4 0.4 0.3 0.2 0.4 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.3 0.2 0.0 0.1 2.4 0.5 0.1 0.2 0.3 240.9 2666.4 0.4 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.1 0.9 0.0 0.1 0.2 0.1 0.0 0.0 0.5 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.5 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.6 30.0 0.0 1.8 0.0 0.0 0.3 0.0 19.6 0.0 0.2 3.0 0.1 1.2 0.0 24.0 0.6 0.0 0.0 0.0 0.0 0.1 1.3 0.0 28.5 1772.7 0.1 0.0 0.5 0.0 0.0 35.4 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 235.7 1.5 0.1 0.0 0.4 0.2 0.4 0.4 0.0 0.0 0.0 2.3 0.1 0.0 0.0 PRKACG PKACg ENSG00000165059 "Protein kinase cAMP-activated catalytic subunit gamma" P22612 9 69012504-69014113 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 152 "testis: 24.6" "Group enriched" "Detected in some" 27 "Early spermatids: 71.0;Late spermatids: 88.4;Spermatocytes: 41.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004530, HPA071185" Supported Uncertain "Cytokinetic bridge,Cytosol" Yes NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Cytokinetic bridge" "CAB004530: AB_628137, HPA071185: AB_2686356" "unprognostic (2.74e-1)" "unprognostic (3.61e-2)" "unprognostic (7.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429242 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "liver: 598.5" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 432.9" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 59.7" "Lineage enriched" "Detected in many" 9 "dendritic cells: 59.7" "Cell line enriched" "Detected in some" 16 "Hep G2: 156.1" "Low region specificity" "Detected in all" "HPA005550, CAB016721, CAB016792" Approved "Secreted to blood" NA NA 5200000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" 0.2 0.0 0.6 0.1 1.1 1.1 0.1 0.6 1.0 0.4 0.0 1.0 0.8 0.1 0.1 0.1 0.2 0.6 0.1 0.6 1.0 14.8 598.5 0.2 0.6 1.6 0.8 0.2 0.3 0.0 0.3 0.1 1.5 0.2 0.6 0.2 0.2 0.1 0.2 0.6 0.8 0.0 0.4 0.4 2.6 0.1 0.8 0.6 0.2 0.0 0.3 0.4 0.2 1.1 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.1 0.0 0.9 0.1 0.4 9.5 0.0 0.3 0.0 0.0 0.2 0.1 7.8 156.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.6 0.4 2.3 0.7 0.0 0.1 0.0 0.0 0.9 0.4 0.0 1.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 6.3 0.0 0.0 59.7 0.0 0.3 0.6 1.1 0.6 1.0 0.6 1.0 1.6 0.8 1.5 0.4 0.8 1.1 0.0 0.0 0.0 0.3 4.1 0.8 0.4 11.2 0.0 0.0 0.1 0.0 0.4 47.1 1.2 0.0 0.0 0.0 24.0 3.9 5.9 0.5 0.1 3.4 0.1 0.6 10.3 18.7 0.1 0.2 0.0 0.7 2.0 0.2 0.0 0.0 12.1 432.9 3.7 0.0 0.5 9.3 0.0 9.3 4.0 0.1 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 8.1 0.0 0.0 0.0 3.8 84.8 3.4 0.0 0.0 0.2 0.3 0.1 0.2 0.0 0.1 0.1 1.1 0.0 1.8 0.3 PROS1 PROS ENSG00000184500 "Protein S" P07225 3 93873051-93980003 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 107.5;heart muscle: 116.6;liver: 283.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 83.1;Hepatocytes: 307.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 64.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 112.3;ASC TERT1: 100.1;HSkMC: 78.2;SK-MEL-30: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007724, HPA023974, CAB032610" Approved "Secreted to blood" NA NA 22500000000 5000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "CAB032610: AB_2237647, HPA007724: AB_1079688, HPA023974: AB_1855738" "unprognostic (2.00e-2)" "unprognostic (2.81e-2)" "unprognostic (9.21e-2)" "unprognostic (8.03e-3)" "unprognostic (3.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.48e-2)" "unprognostic (3.07e-1)" "unprognostic (5.18e-2)" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.35e-4)" "unprognostic (4.90e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.42e-5)" 33.6 8.7 1.7 8.1 1.3 0.3 24.7 1.6 2.7 14.9 107.5 17.3 13.5 16.4 2.0 16.6 19.4 33.7 116.6 3.2 2.2 37.7 283.1 39.2 4.7 2.1 2.4 32.6 5.6 13.5 8.5 32.0 2.2 8.4 21.6 4.6 12.3 10.3 4.9 20.5 20.6 19.2 1.6 11.2 10.5 5.0 2.3 1.5 17.0 16.9 3.7 18.5 15.1 1.7 0.4 2.7 3.0 27.1 112.3 100.1 1.6 4.6 9.4 1.0 6.6 12.7 1.4 0.0 30.0 3.0 18.8 0.0 1.4 0.9 1.8 0.1 7.3 51.4 1.4 29.8 8.7 1.5 1.2 78.2 0.4 4.0 0.6 63.0 7.2 3.7 32.8 0.1 49.2 0.0 0.1 0.0 3.1 2.7 6.5 0.3 1.2 0.0 27.7 0.0 7.6 19.8 5.0 0.0 157.0 0.6 0.0 19.9 9.4 14.8 2.8 8.2 1.7 0.0 0.0 0.0 60.4 30.4 27.8 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 3.2 1.7 1.3 1.6 2.7 3.2 2.2 2.1 2.4 2.2 1.6 2.3 1.7 55.9 64.1 33.8 17.9 1.9 14.8 3.6 2.1 4.0 0.5 1.7 14.0 44.6 14.3 7.5 1.8 10.4 0.6 0.5 7.5 3.9 9.8 3.2 2.1 30.7 47.1 15.7 16.4 28.4 4.4 0.7 83.1 2.0 1.1 30.9 5.0 65.7 307.1 12.8 1.7 19.7 11.6 0.0 31.5 20.6 6.3 28.6 14.6 19.6 27.2 1.3 22.8 0.0 10.6 4.6 5.6 19.3 36.9 0.3 4.5 1.9 42.2 56.6 8.1 13.1 32.4 28.4 0.4 0.7 11.8 33.2 1.6 2.1 10.8 12.6 2.3 RAD51 "BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA" ENSG00000051180 "RAD51 recombinase" Q06609 15 40694774-40732340 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.7;testis: 24.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Extravillous trophoblasts: 67.2;Spermatocytes: 53.6;Spermatogonia: 24.8;Syncytiotrophoblasts: 25.3" "Cancer enhanced" "Detected in all" "testis cancer: 19.9" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010381, HPA039310" Enhanced Supported "Nucleoli rim,Cytosol" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoli rim" Cytosol "CAB010381: AB_2253533, HPA039310: AB_2676434" "prognostic unfavorable (7.94e-4)" "unprognostic (7.20e-3)" "unprognostic (1.22e-1)" "unprognostic (2.72e-2)" "unprognostic (8.23e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (9.33e-4)" "unprognostic (3.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-3)" "unprognostic (2.53e-3)" "unprognostic (0.00e+0)" "unprognostic (2.26e-2)" "unprognostic (2.34e-1)" "unprognostic (9.59e-2)" "unprognostic (1.94e-2)" 0.9 0.6 0.4 5.5 0.5 10.5 1.9 1.7 0.7 1.0 0.6 8.3 3.2 1.2 0.4 4.2 0.7 1.3 0.6 0.4 0.5 0.5 1.3 1.1 11.0 0.4 0.3 0.6 1.4 0.5 0.2 6.8 0.5 0.8 9.1 0.3 1.0 0.3 1.0 3.1 4.1 2.4 0.1 2.4 1.8 24.3 0.3 15.7 0.6 0.5 13.3 1.7 1.5 0.5 33.8 16.1 33.4 16.3 4.4 7.8 31.1 54.9 16.5 43.3 43.8 35.4 22.1 20.4 26.8 20.9 18.9 67.7 56.6 22.1 42.3 39.0 22.2 47.7 28.2 30.4 0.4 37.9 28.5 1.7 2.9 30.0 13.5 6.4 22.5 48.5 59.6 55.8 36.6 28.5 54.4 43.6 35.2 69.2 19.0 61.0 49.0 30.7 15.4 45.3 15.4 27.0 23.6 41.4 8.5 39.2 27.0 39.4 9.9 32.8 22.2 48.7 27.2 12.0 65.1 59.8 16.3 78.0 33.5 1.3 0.6 1.7 2.4 1.3 0.6 1.7 2.5 3.2 1.0 1.1 0.6 1.2 1.2 1.8 1.4 0.9 5.9 1.2 0.4 0.5 1.7 0.7 0.4 0.5 0.4 0.3 0.5 0.1 0.3 0.5 0.0 0.0 0.0 0.3 1.9 3.6 1.5 2.0 0.0 0.8 0.1 0.0 0.9 0.0 1.0 0.0 0.0 35.3 1.4 3.0 0.0 0.0 5.7 0.2 0.2 1.0 0.0 16.0 1.6 0.0 67.2 1.3 2.0 0.2 0.0 0.6 2.2 0.2 12.7 0.0 1.2 5.3 2.0 1.6 1.7 5.3 0.6 0.5 0.0 1.0 0.3 0.3 2.1 0.5 0.6 0.1 5.0 0.7 8.2 0.9 1.0 0.0 0.1 0.0 0.0 0.5 0.9 53.6 24.8 3.9 1.6 25.3 1.2 0.1 8.0 2.1 RAD51C "FANCO, RAD51L2" ENSG00000108384 "RAD51 paralog C" O43502 17 58692573-58735611 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 117.7;Spermatocytes: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 319.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045198 Supported "Nucleoplasm,Vesicles,Cell Junctions,Mitochondria,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Mitochondria, Cytosol" "Vesicles, Cell Junctions" "HPA045198: AB_2679250" "unprognostic (5.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.23e-2)" "unprognostic (6.20e-2)" "unprognostic (1.83e-1)" "unprognostic (4.59e-2)" "prognostic unfavorable (8.68e-5)" "unprognostic (3.65e-2)" "unprognostic (2.91e-2)" "unprognostic (1.03e-2)" "prognostic favorable (5.33e-4)" "unprognostic (2.55e-1)" "unprognostic (2.62e-2)" "unprognostic (7.62e-2)" "unprognostic (2.41e-1)" "unprognostic (9.52e-2)" "unprognostic (2.42e-2)" 10.8 20.2 15.5 10.0 15.7 23.1 15.3 19.0 18.4 10.8 13.4 12.4 7.5 12.6 22.0 13.0 11.2 11.0 25.7 16.4 15.0 12.8 13.3 8.8 22.0 14.9 13.8 12.5 10.6 20.1 10.5 15.1 16.0 17.4 14.5 13.5 10.7 12.0 18.3 10.6 8.7 13.8 13.2 12.2 11.6 20.2 14.6 21.2 12.3 17.3 19.1 10.9 8.6 18.2 63.7 72.1 43.3 48.5 22.9 19.6 100.1 34.2 14.5 43.5 55.3 31.0 39.3 37.4 48.9 23.5 58.8 23.3 59.5 46.6 81.7 91.6 123.0 53.0 84.6 119.4 23.3 69.1 45.0 12.1 42.2 47.8 38.6 24.0 50.0 60.9 83.6 48.5 37.0 319.1 96.8 95.3 12.1 42.5 66.5 62.1 69.5 69.8 26.9 39.6 54.3 49.6 27.3 12.0 53.5 11.1 39.2 71.6 16.5 37.6 100.1 34.3 42.4 44.1 187.2 111.5 38.3 67.1 42.0 27.6 9.2 12.5 15.6 14.3 15.2 18.0 16.9 17.2 15.9 17.3 18.2 17.4 5.1 15.0 12.5 14.3 27.1 11.0 15.5 15.7 19.0 18.4 16.4 15.0 14.9 13.8 16.0 13.2 14.6 18.2 20.5 19.2 13.9 10.1 20.5 11.9 18.7 42.9 15.9 15.0 25.1 34.0 63.7 7.2 20.9 16.5 6.2 67.8 15.0 7.1 58.7 25.7 117.7 17.3 13.0 19.3 6.7 43.8 21.5 18.6 94.1 19.8 7.1 13.0 22.9 23.3 15.7 15.7 33.4 16.8 17.7 11.7 32.6 16.1 47.7 65.4 17.4 21.8 24.9 13.1 18.7 31.3 21.6 23.1 22.8 13.0 10.4 15.4 28.5 17.2 5.7 24.6 14.1 26.9 32.9 14.7 23.9 140.7 98.3 15.9 10.7 36.3 20.5 28.2 15.3 13.9 RASGRP2 CALDAG-GEFI ENSG00000068831 "RAS guanyl releasing protein 2" Q7LDG7 11 64726911-64745456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 147.3;lymphoid tissue: 140.5" "Cell type enhanced" "Detected in many" "B-cells: 125.5;dendritic cells: 86.1;Kupffer cells: 77.3;Macrophages: 72.2;NK-cells: 98.9;Sertoli cells: 131.5" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 103.4;HL-60: 192.8;NB-4: 347.1;REH: 105.0;THP-1: 108.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015635, HPA015667" Approved Supported "Plasma membrane" NA NA 1900000 "Cluster 37: B-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA015635: , HPA015667: AB_1856090" "unprognostic (5.96e-2)" "unprognostic (3.24e-3)" "unprognostic (5.55e-2)" "unprognostic (1.50e-2)" "unprognostic (3.52e-2)" "unprognostic (4.74e-5)" "unprognostic (1.11e-2)" "unprognostic (7.36e-3)" "unprognostic (2.02e-1)" "unprognostic (3.33e-1)" "unprognostic (4.91e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.08e-1)" "unprognostic (5.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.23e-1)" 23.8 10.1 16.1 52.9 35.5 147.3 16.8 9.6 22.4 20.1 7.1 37.5 6.6 28.3 4.6 9.1 29.2 8.7 51.7 13.4 13.4 15.8 10.1 29.5 106.0 12.4 16.3 9.1 4.1 1.0 5.5 10.9 11.9 23.2 5.3 1.3 4.6 18.6 12.2 6.1 86.4 15.0 9.5 140.5 17.5 11.9 20.7 34.6 10.6 10.2 62.0 26.7 15.5 9.8 0.1 0.1 3.0 0.1 0.0 0.3 8.7 1.3 0.2 1.2 0.8 1.5 0.2 62.8 2.7 0.2 0.8 0.7 5.4 0.9 0.3 0.3 1.7 103.4 0.0 0.4 0.3 192.8 35.9 0.0 0.0 0.5 0.0 0.0 0.1 25.9 4.1 1.1 0.0 1.4 45.4 347.1 2.5 0.4 0.0 105.0 0.2 4.4 0.0 0.0 0.5 2.3 0.1 0.1 0.0 2.2 0.6 108.5 0.6 0.0 2.0 1.5 0.1 0.5 0.1 58.9 0.0 58.2 0.0 64.4 34.1 59.9 70.4 88.0 37.3 170.7 72.9 57.2 34.5 100.2 92.7 83.1 70.9 55.3 105.8 85.9 93.8 67.5 16.1 35.5 9.6 22.4 13.4 13.4 12.4 16.3 11.9 9.5 20.7 9.8 27.4 3.2 1.8 2.6 125.5 2.3 0.1 0.0 0.0 2.6 1.6 3.7 53.1 2.8 0.0 0.0 0.0 1.7 86.1 0.1 0.0 0.0 6.6 1.9 27.1 13.5 0.0 24.2 6.0 0.0 1.3 6.6 2.6 1.2 3.8 5.7 31.4 1.7 6.1 0.0 12.2 0.1 0.0 77.3 19.7 19.5 18.0 72.2 0.0 6.5 55.8 0.7 98.9 2.5 0.9 0.0 0.0 47.8 28.6 0.1 0.4 0.9 0.7 2.5 131.5 5.4 56.8 18.0 43.9 0.9 1.3 11.8 61.0 0.8 0.3 0.2 RFWD3 "FANCW, FLJ10520, RNF201" ENSG00000168411 "Ring finger and WD repeat domain 3" Q6PCD5 16 74621399-74666877 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 47.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048258, HPA075649" Approved Enhanced Nucleoplasm,Cytosol No No "Cluster 42: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA048258: AB_2680332, HPA075649: AB_2686761" "unprognostic (4.79e-2)" "unprognostic (6.45e-3)" "unprognostic (6.35e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-1)" "unprognostic (1.97e-1)" "unprognostic (1.11e-3)" "unprognostic (5.04e-2)" "unprognostic (3.64e-2)" "unprognostic (1.01e-1)" "unprognostic (4.03e-3)" "unprognostic (2.53e-3)" "unprognostic (1.73e-3)" "unprognostic (2.84e-1)" "unprognostic (4.31e-1)" "unprognostic (5.74e-2)" "unprognostic (3.29e-1)" 5.2 3.9 2.5 9.9 3.5 47.7 7.6 4.0 3.2 6.4 4.4 8.0 6.5 6.2 5.3 9.4 6.8 6.5 2.9 2.3 2.9 6.7 5.8 6.1 15.4 3.3 3.1 7.0 10.2 6.8 3.8 8.0 3.2 4.9 9.3 6.2 5.8 5.1 3.3 12.6 6.1 6.1 2.8 8.1 6.2 25.2 3.4 27.1 6.6 2.7 16.7 7.2 6.8 4.7 46.1 57.5 42.6 31.2 8.8 11.9 47.8 40.5 30.9 63.0 54.5 75.4 46.8 63.6 32.1 31.8 31.6 53.9 70.3 42.1 76.9 20.0 42.1 56.3 46.0 43.0 7.6 57.3 56.3 8.6 13.2 79.6 48.7 16.3 27.3 53.2 86.7 27.7 48.1 72.8 84.0 52.2 84.0 26.8 27.7 128.7 28.8 55.9 22.7 47.8 31.5 33.6 65.2 22.8 28.8 38.2 41.7 48.4 26.7 46.0 43.9 26.2 51.4 37.4 75.1 188.3 32.8 43.5 57.0 12.1 4.4 6.5 5.5 4.1 6.1 4.9 4.5 5.1 4.6 5.4 6.7 4.8 4.9 6.2 7.7 3.5 7.2 4.4 2.5 3.5 4.0 3.2 2.3 2.9 3.3 3.1 3.2 2.8 3.4 4.7 6.0 0.0 5.9 4.2 13.2 10.8 6.8 4.0 10.2 6.6 8.4 8.3 3.9 2.8 5.4 1.8 10.4 12.1 15.3 7.6 11.7 6.2 5.4 6.9 5.7 7.2 9.5 22.5 8.9 7.6 8.3 5.9 5.1 6.6 4.5 13.5 11.7 7.4 8.9 3.3 7.1 9.7 2.0 12.2 6.0 6.3 3.7 7.8 16.0 15.0 7.6 3.0 10.3 6.6 15.2 10.0 2.7 4.1 11.6 12.7 4.3 4.6 5.9 6.7 6.6 6.4 5.6 48.5 31.7 9.5 9.2 7.5 10.6 3.6 9.5 11.4 RHAG "CD241, RH50A, SLC42A1" ENSG00000112077 "Rh associated glycoprotein" Q02094 6 49605175-49636839 "CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "bone marrow: 119.6" "Cell type enriched" "Detected in some" 170 "Erythroid cells: 494.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 202 "HEL: 506.0;K-562: 491.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA046051, HPA055331" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Endoplasmic reticulum" "HPA046051: , HPA055331: AB_2682785" "unprognostic (8.16e-2)" "unprognostic (6.86e-2)" "unprognostic (1.25e-3)" "unprognostic (1.65e-1)" 0.2 0.0 0.0 0.0 0.0 119.6 0.0 0.0 0.0 0.7 0.0 0.5 0.1 0.1 0.0 0.1 0.2 0.0 2.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.2 0.2 0.0 0.2 0.6 0.0 0.1 0.4 0.0 0.0 1.7 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 506.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 491.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.4 0.1 0.3 0.0 494.2 0.2 0.2 0.6 0.3 0.0 0.6 2.5 0.0 1.1 0.1 0.5 0.0 0.1 0.0 0.0 0.6 0.3 2.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.4 0.1 0.0 0.0 RPL11 "L11, uL5" ENSG00000142676 "Ribosomal protein L11" P62913 1 23691742-23696835 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA002734 Approved NA NA 420000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 20: HeLa - Mitochondria" "Cluster 32: Non-specific - Translation" "HPA002734: AB_1079838" "prognostic favorable (2.55e-4)" "unprognostic (3.98e-2)" "unprognostic (7.77e-2)" "unprognostic (3.30e-2)" "unprognostic (1.21e-1)" "unprognostic (6.70e-2)" "unprognostic (4.51e-3)" "unprognostic (4.94e-2)" "unprognostic (1.70e-2)" "unprognostic (1.25e-1)" "unprognostic (1.61e-1)" "unprognostic (8.92e-2)" "prognostic unfavorable (5.93e-6)" "unprognostic (8.65e-2)" "unprognostic (2.42e-3)" "unprognostic (5.41e-2)" "unprognostic (1.90e-1)" 2197.5 1349.1 758.6 346.3 785.5 806.8 2374.3 764.5 1074.4 2495.3 749.2 1713.2 317.9 1551.7 1107.6 2043.6 1984.4 265.0 1422.6 736.6 795.9 1543.3 1447.9 1462.7 701.7 809.3 768.6 3879.7 3207.9 637.6 1144.7 507.5 800.5 1788.9 985.9 386.7 1763.2 645.4 1526.0 2752.4 1715.1 689.7 795.4 1949.2 2314.0 460.2 781.0 1219.1 1414.8 880.4 1842.1 1717.0 2090.6 813.7 662.3 1068.4 1257.9 639.1 2123.4 2978.6 437.2 431.4 1845.0 1641.4 1217.1 1937.6 719.7 1370.3 470.9 1511.4 665.7 543.3 1611.2 2187.0 1824.5 492.7 2157.9 633.6 3936.3 2610.9 1589.8 1086.5 499.1 2928.6 3156.8 1394.3 2498.9 2009.5 1767.1 2371.5 747.4 713.2 1768.6 2068.0 650.7 1737.1 313.0 2165.7 1216.9 800.7 608.8 1319.0 1877.2 1173.3 491.0 601.2 337.3 697.8 1360.9 1083.0 514.3 1352.0 524.4 391.2 546.3 672.8 554.2 658.6 643.2 968.8 499.0 1529.0 458.4 1028.5 1455.4 431.6 1270.6 1217.3 2184.9 3261.3 2593.8 1881.3 1736.4 2812.9 3379.5 2575.7 211.5 1567.3 990.9 1725.9 2092.7 5471.7 758.6 785.5 764.5 1074.4 736.6 795.9 809.3 768.6 800.5 795.4 781.0 813.7 3418.4 1179.5 2275.5 43.8 6392.9 6628.5 7570.4 5085.6 5306.4 352.5 7418.2 12717.3 617.0 3247.0 2566.9 1125.5 154.3 4728.5 4068.6 1693.1 4807.1 2915.5 1052.2 1501.4 3771.6 3056.2 2161.7 2833.3 27.2 6657.0 7929.6 2968.4 2193.7 2008.2 2101.5 4064.4 3524.6 3426.2 3894.7 206.9 29.6 3865.1 1462.8 4584.6 6984.2 2224.6 4602.4 3661.8 3758.4 46.9 5264.1 1582.9 3300.8 24.1 64.1 4149.5 3575.9 2083.0 3334.0 6327.0 4545.4 5429.1 1260.7 664.2 1413.4 3920.1 3380.5 604.1 699.6 6295.1 7993.4 4651.9 5029.1 4961.7 4420.7 7534.5 RPL15 "EC45, L15, RPL10, RPLY10, RPYL10" ENSG00000174748 "Ribosomal protein L15" P61313 3 23916591-23924374 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 290000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "unprognostic (8.73e-3)" "unprognostic (3.13e-2)" "unprognostic (1.06e-2)" "unprognostic (5.77e-3)" "unprognostic (1.16e-2)" "unprognostic (8.40e-2)" "unprognostic (1.76e-3)" "unprognostic (4.43e-2)" "unprognostic (1.65e-1)" "unprognostic (1.41e-1)" "unprognostic (3.54e-2)" "unprognostic (6.15e-2)" "unprognostic (1.53e-2)" "unprognostic (1.32e-1)" "unprognostic (1.65e-1)" "unprognostic (1.78e-1)" "unprognostic (2.17e-2)" 1235.0 974.6 932.8 988.5 948.8 3173.3 1985.3 910.8 1017.8 1476.6 865.3 1256.2 916.2 1233.3 1364.2 1590.2 1684.8 1032.7 1064.9 889.6 947.1 924.1 963.9 881.7 2139.0 956.2 935.2 3508.3 2314.0 1132.0 875.3 999.3 954.7 1056.4 1082.2 492.2 2541.7 933.6 1204.2 1598.4 944.7 1146.3 1028.4 1135.6 1189.7 543.9 985.7 2145.3 1420.4 1470.7 1967.5 1622.0 1298.3 983.7 1884.4 1672.6 1865.3 2205.4 2938.4 4771.0 2306.5 1735.1 3111.2 2614.8 2272.5 1911.8 2160.2 3773.1 1663.6 2599.8 1395.8 1246.8 2257.1 3847.8 1873.7 1781.3 3198.5 1482.3 1665.5 2318.9 3919.5 2624.0 1883.9 4784.3 5359.8 2903.6 4909.4 3783.5 3360.8 2616.7 1920.5 3044.4 2731.4 2598.3 3423.7 3345.9 3254.1 2354.3 2745.2 2980.8 1645.5 4025.3 2762.8 2203.8 987.6 2402.2 1020.5 4416.6 3791.8 1655.3 2958.9 5102.2 1849.1 1569.5 2056.3 1645.1 3196.8 2579.1 3758.6 3500.8 1570.9 3483.4 1852.3 897.2 2250.3 454.1 1698.4 1878.9 2960.6 3476.6 2599.4 2357.9 2917.1 3310.7 3182.8 2831.7 263.1 2346.0 1602.6 2369.7 2475.9 6597.8 932.8 948.8 910.8 1017.8 889.6 947.1 956.2 935.2 954.7 1028.4 985.7 983.7 1499.2 746.8 1100.3 44.7 3602.1 7074.5 6959.4 8223.9 3122.1 541.8 6066.8 6379.1 385.1 2546.4 3484.1 1029.9 181.4 4812.5 2798.4 1007.2 4187.0 3163.6 3239.1 1167.3 1989.0 2798.6 1720.1 2338.9 63.9 4491.5 6879.4 2261.8 1083.6 1607.8 1478.8 2969.2 2682.2 1755.9 3583.6 277.6 77.7 2855.1 3013.0 3552.7 6451.3 4965.7 3662.3 2601.6 3966.5 50.6 4609.7 1412.2 2856.9 45.8 91.3 3499.5 2558.2 2337.3 2291.1 7001.0 1750.8 3801.2 1422.6 570.1 1360.8 2679.8 4368.3 1786.6 962.8 4001.9 8678.9 5061.5 2967.3 3017.0 3549.9 7926.6 RPL18 L18 ENSG00000063177 "Ribosomal protein L18" Q07020 19 48615328-48619184 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "NB-4: 16079.5" "Low region specificity" "Detected in all" HPA046572 Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 290000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA046572: AB_2679705" "unprognostic (2.12e-2)" "unprognostic (1.86e-2)" "unprognostic (7.30e-2)" "unprognostic (2.57e-2)" "unprognostic (3.48e-3)" "unprognostic (4.76e-2)" "unprognostic (3.21e-3)" "unprognostic (2.80e-1)" "unprognostic (2.39e-1)" "unprognostic (9.15e-2)" "unprognostic (6.15e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (2.40e-1)" "unprognostic (3.04e-2)" "unprognostic (6.36e-2)" "unprognostic (1.27e-2)" 1000.7 1074.9 985.7 753.7 981.5 1976.6 1333.2 932.2 1170.2 1491.2 910.5 995.0 912.2 1051.5 782.6 1786.5 1415.0 719.4 754.8 924.1 955.5 756.7 974.7 730.6 1740.2 980.7 953.9 3084.6 2343.7 580.6 905.7 746.8 972.6 1262.1 814.4 139.0 1779.2 702.0 1056.9 1944.3 956.6 709.9 999.1 1151.6 1122.4 332.2 993.5 1091.5 880.0 643.0 1399.0 1017.9 1356.0 989.5 1874.4 2697.1 1148.7 1520.6 1267.0 2299.6 1455.1 1042.7 1489.0 1754.3 1471.6 2497.8 1407.6 3436.1 874.1 1007.2 803.9 1400.0 1211.2 2056.9 844.3 1349.6 3380.2 1286.3 1234.0 2438.1 2166.6 1793.6 1309.6 2633.8 3015.8 1031.9 1603.7 1760.0 1836.8 2149.2 1629.3 2043.5 1297.6 2236.5 1926.2 16079.5 1421.6 3171.4 1469.5 2058.1 1073.4 2438.4 1527.9 2370.7 1410.8 1739.1 850.4 2306.0 2082.3 641.1 1241.4 2618.1 1220.9 1032.3 1275.0 727.4 2119.8 1970.9 2939.2 1934.2 649.6 2246.7 1257.7 381.1 1022.8 217.6 1066.6 890.3 1889.0 2384.8 1921.2 1461.0 1380.1 2368.0 2373.9 1981.4 140.7 1357.8 681.2 1451.1 1707.2 3192.5 985.7 981.5 932.2 1170.2 924.1 955.5 980.7 953.9 972.6 999.1 993.5 989.5 1729.2 593.0 983.1 22.9 4066.2 4468.5 4767.6 3561.4 4933.7 393.5 3680.3 5354.2 264.0 1637.1 1809.1 708.1 143.9 3891.0 2534.2 1344.7 1387.2 1853.2 80.5 1067.0 2619.6 1812.4 1673.5 1713.1 21.7 4530.2 5344.1 1765.9 1597.9 1584.8 1021.6 2791.1 1810.1 1426.6 2225.3 134.6 28.2 3186.8 1253.2 2491.6 3341.9 221.3 3248.9 2059.4 2278.5 16.9 2958.8 1413.2 2345.1 22.6 51.3 3022.6 2516.1 1459.7 2801.6 4727.0 2534.3 1832.5 697.3 433.7 1032.1 2596.1 2246.5 283.4 558.4 5421.3 5559.5 4138.0 2961.3 3084.2 3163.6 5183.8 RPL26 L26 ENSG00000161970 "Ribosomal protein L26" P61254 17 8377516-8383213 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030449, CAB037301" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "CAB037301: AB_796168, HPA030449: AB_10602125" "unprognostic (2.02e-2)" "unprognostic (3.73e-1)" "unprognostic (2.12e-1)" "unprognostic (2.76e-1)" "unprognostic (6.82e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (3.95e-1)" "unprognostic (6.59e-3)" "unprognostic (1.16e-1)" "unprognostic (1.12e-1)" "unprognostic (7.15e-2)" "unprognostic (1.96e-3)" "unprognostic (2.73e-1)" "unprognostic (1.08e-1)" "unprognostic (5.44e-2)" "unprognostic (2.38e-1)" 2647.0 1834.7 1444.0 1225.0 1483.6 3862.9 4202.6 1437.9 2302.9 2923.7 1394.3 2148.4 1286.2 1911.1 2229.1 2565.8 2254.3 1396.5 1756.1 1402.1 1503.8 2006.1 1826.0 1615.6 3047.7 1494.3 1433.2 4732.1 3616.6 1250.6 1067.0 1536.3 1496.7 2026.5 2044.1 815.9 2073.2 1272.7 2625.9 3123.9 1921.8 1379.7 1515.1 2060.3 2137.9 548.8 1463.6 2241.2 1926.2 1911.5 2840.0 2178.2 2560.6 1538.3 2791.7 2553.3 2428.3 2899.9 4595.7 7595.7 2377.2 2357.4 3627.6 3234.3 2430.6 2732.4 1406.4 4875.0 2641.6 2899.3 1278.3 3012.9 3173.2 4954.7 3806.7 1824.4 5711.8 1893.9 2682.1 3218.0 5344.6 2835.2 2347.9 6463.5 9908.8 2638.4 7949.9 4443.9 4106.5 2739.0 2210.9 1423.8 3478.6 1967.6 3153.9 3903.4 2275.5 2924.4 1691.8 3097.3 2453.7 3094.4 4394.8 2116.9 1014.7 2144.2 1268.6 2353.7 5882.6 2142.4 2417.5 3740.1 2492.5 1270.3 1564.9 1765.2 4201.2 1119.0 1485.1 2188.6 2074.1 4071.7 1920.7 490.8 1528.6 300.6 1323.8 1277.1 1928.7 2409.5 1960.7 1734.1 1901.2 2152.5 2270.0 2008.9 167.6 1562.4 1173.0 1634.7 1803.3 3235.4 1444.0 1483.6 1437.9 2302.9 1402.1 1503.8 1494.3 1433.2 1496.7 1515.1 1463.6 1538.3 2207.3 897.4 1239.5 29.0 4966.6 5577.5 3390.4 3434.2 4618.4 256.5 5263.8 5691.4 292.0 3039.7 1994.1 1004.2 133.5 4514.0 3481.7 1395.1 3946.3 2664.5 884.0 1146.1 2485.1 2507.8 2284.5 2894.1 39.3 4897.5 7026.7 2100.3 1725.3 1470.3 1868.6 1738.7 3416.5 2960.2 3431.5 136.3 33.9 4440.7 1062.0 5356.7 6335.6 1657.9 4777.0 3085.5 3198.1 45.9 6036.5 747.5 3887.8 22.1 39.7 3561.4 3590.4 2157.9 2546.9 3577.0 3412.0 5475.1 856.5 477.7 1512.0 4011.2 2218.8 568.4 716.4 6164.5 7093.8 4568.3 3804.2 2012.8 4955.7 3367.7 RPL27 L27 ENSG00000131469 "Ribosomal protein L27" P61353 17 42998273-43002959 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Cancer-related genes, Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA002649 Approved Enhanced Nucleoplasm,Nucleoli NA NA 170000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Nucleoli Nucleoplasm "HPA002649: AB_1079840" "unprognostic (8.53e-3)" "unprognostic (7.15e-2)" "unprognostic (3.97e-2)" "unprognostic (2.81e-2)" "unprognostic (4.99e-2)" "unprognostic (4.31e-2)" "unprognostic (1.91e-3)" "unprognostic (7.32e-2)" "unprognostic (9.17e-2)" "unprognostic (1.19e-1)" "unprognostic (5.12e-2)" "unprognostic (3.86e-1)" "prognostic unfavorable (7.80e-8)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" 1871.8 1549.8 1111.3 1009.9 1116.5 2929.2 1962.9 1098.5 1512.7 2052.8 1111.9 1884.1 802.3 1550.5 994.9 1984.2 1652.8 740.8 1495.4 1092.8 1126.1 1276.4 1316.9 1278.5 1999.4 1122.6 1109.6 2598.8 2232.2 850.4 894.8 951.0 1119.0 1483.8 894.1 394.5 1530.7 749.8 2544.6 2726.6 1467.8 854.4 1124.4 1802.0 1559.6 409.4 1127.1 1682.4 1067.7 1510.1 1378.5 1650.9 1820.8 1132.8 2288.0 2867.0 1701.7 2480.6 2983.9 4422.4 2741.5 2594.6 2162.4 2777.2 1979.1 4107.0 1751.0 4309.7 2143.3 2087.9 1477.4 1948.8 2000.9 3363.7 2670.5 1996.4 4741.8 1694.3 2147.4 4431.8 3669.4 4908.1 1698.9 4175.7 2847.4 1867.0 2381.3 2795.0 2356.9 2241.9 3237.8 2584.2 2618.6 2253.4 4127.7 4153.0 2577.8 2634.0 1821.4 2841.1 4775.1 4927.8 2374.2 3092.9 1909.6 2094.8 1016.8 1982.1 4341.5 2299.8 3341.2 5076.5 2617.1 2021.7 1988.7 2497.2 3885.7 2219.6 4004.7 4327.4 1816.5 3030.7 2107.7 1007.1 1762.8 553.5 1773.1 1633.6 2518.3 3055.1 2633.3 2095.8 2115.1 2792.7 2987.8 2673.6 358.7 2155.7 1284.9 2726.2 2059.6 4601.4 1111.3 1116.5 1098.5 1512.7 1092.8 1126.1 1122.6 1109.6 1119.0 1124.4 1127.1 1132.8 770.3 734.0 1103.9 11.1 2217.2 2530.2 2296.2 1759.2 941.8 138.9 1779.8 1725.0 725.8 1302.6 1175.0 518.6 89.6 2093.8 1873.8 948.5 1496.7 1822.6 435.6 524.0 1202.0 1245.7 912.0 1291.4 9.9 3028.9 3551.3 1025.1 510.7 660.9 991.3 983.7 1689.1 1859.0 2118.7 65.6 10.7 2016.4 671.4 2560.1 2977.0 1070.0 2434.3 1522.8 1426.5 22.5 3232.7 722.9 2669.4 7.5 16.3 2450.0 1585.4 1279.6 957.2 2462.7 1301.2 2383.0 574.6 230.6 867.8 1669.6 1874.7 384.8 476.4 1644.1 3371.3 2184.8 1833.0 1266.3 2175.4 2628.2 RPL35 L35 ENSG00000136942 "Ribosomal protein L35" P42766 9 124857880-124861981 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006047 Approved Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA006047: AB_1856443" "unprognostic (1.16e-2)" "unprognostic (5.42e-3)" "unprognostic (3.04e-2)" "unprognostic (3.69e-2)" "unprognostic (1.42e-2)" "unprognostic (9.40e-3)" "unprognostic (2.67e-2)" "unprognostic (2.21e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (1.45e-1)" "unprognostic (1.37e-3)" "unprognostic (6.58e-2)" "unprognostic (2.74e-2)" "unprognostic (1.47e-1)" "unprognostic (2.31e-2)" 1898.8 1508.6 1462.7 973.8 1489.9 2729.0 1959.9 1434.2 1780.8 2116.4 1400.9 1768.2 809.5 1343.7 793.9 2540.7 1694.2 839.0 1467.3 1421.2 1502.6 1380.8 1746.4 1271.3 1990.2 1480.9 1456.2 3011.1 3413.2 853.0 1225.5 743.7 1484.9 1709.2 708.6 273.8 1811.1 736.6 2552.7 3033.7 1383.2 717.4 1498.9 1708.9 1567.2 669.4 1507.0 1569.3 1349.1 1589.5 1380.7 1655.0 2080.7 1516.5 2104.6 3225.4 1780.5 2469.8 1923.1 4033.9 2443.2 1626.3 2589.3 3295.8 2235.0 5370.0 2030.1 3127.8 1631.9 1836.1 1970.9 3986.3 2097.6 3578.7 1209.0 1929.9 3742.5 1266.5 4071.9 3541.9 3433.2 2856.0 1626.0 3759.1 5481.9 1973.9 3480.3 1809.7 2473.6 2927.1 2775.1 3857.2 2523.6 6848.9 3384.5 6510.7 3362.5 6272.1 4016.6 2849.6 2744.6 7026.2 2896.8 2469.0 2412.8 1946.7 1466.3 3452.9 3423.3 876.8 3508.4 4592.6 1269.5 1472.5 1558.9 2578.9 3357.6 2151.5 5523.9 4935.8 2059.7 2982.8 2523.1 753.7 1769.0 695.2 2322.2 1602.3 3101.1 4455.5 3086.5 2676.2 2564.2 4099.1 3218.0 2834.7 221.1 2414.5 1352.2 3650.6 2715.7 7293.7 1462.7 1489.9 1434.2 1780.8 1421.2 1502.6 1480.9 1456.2 1484.9 1498.9 1507.0 1516.5 1202.7 637.8 1152.6 15.3 3024.6 5507.5 4326.2 3639.5 1752.9 221.3 4389.9 4459.0 750.7 1732.9 1653.3 1134.8 85.5 2799.3 2227.9 1319.7 2701.9 2347.8 1562.9 826.5 1969.5 1751.1 1298.1 2073.6 9.0 6137.7 4495.9 1544.5 976.6 1135.5 1308.1 2164.6 2362.3 3182.4 2826.7 109.4 9.7 3044.7 1249.2 3375.2 4877.3 6025.8 2777.4 1833.7 2821.1 11.2 3348.5 925.7 2482.0 9.5 16.2 3542.4 2346.8 1285.2 1756.4 4196.5 2319.0 3772.0 618.9 410.0 992.7 2309.7 3771.2 790.9 905.5 3017.8 7263.3 2464.8 2473.5 1760.1 3346.1 3998.4 RPL35A "eL33, GIG33, L35A" ENSG00000182899 "Ribosomal protein L35a" P18077 3 197950190-197956610 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, tRNA-binding" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 11000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "unprognostic (9.48e-3)" "unprognostic (1.69e-2)" "unprognostic (1.78e-1)" "unprognostic (5.01e-2)" "unprognostic (5.51e-2)" "unprognostic (5.89e-3)" "prognostic unfavorable (9.89e-4)" "unprognostic (2.51e-1)" "unprognostic (3.41e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.43e-4)" "unprognostic (2.54e-2)" "prognostic unfavorable (1.37e-6)" "unprognostic (1.03e-2)" "unprognostic (4.65e-2)" "unprognostic (3.85e-2)" "unprognostic (7.72e-2)" 1060.9 919.0 554.5 548.3 560.9 1161.6 1209.1 556.6 875.5 1438.4 549.5 971.4 520.6 971.4 599.3 1071.3 1200.8 252.4 966.5 543.8 571.1 753.4 643.4 725.7 776.3 560.9 550.3 2394.5 1789.9 502.8 697.1 374.5 562.3 950.7 463.3 326.6 899.8 418.6 879.5 1311.5 830.6 379.1 574.1 927.0 1025.4 358.9 568.7 907.9 754.4 616.9 736.3 892.3 1148.1 574.3 2272.2 669.9 1091.7 982.0 737.1 1529.0 1215.9 1067.3 916.3 1121.8 841.4 2189.3 934.5 1922.7 3792.9 680.8 669.3 1163.5 924.8 990.5 1121.2 439.8 1629.0 1117.0 1082.0 1513.0 1173.4 1973.2 899.3 1383.4 1121.0 605.3 1672.3 1389.3 1085.5 810.5 1049.2 2182.5 1071.6 3132.8 1295.6 2533.4 1729.9 1681.6 1618.3 1221.8 942.7 2976.8 1286.5 1394.9 1052.5 969.8 676.7 2283.5 3031.5 1176.3 3953.6 3116.9 1031.2 652.8 872.6 979.3 2042.8 1709.4 2192.8 2579.9 934.9 3009.7 1045.6 461.7 737.7 233.9 705.6 543.2 1155.3 1223.1 1275.3 970.1 796.3 1105.2 1645.4 1249.0 118.2 741.6 513.4 929.9 878.3 2092.3 554.5 560.9 556.6 875.5 543.8 571.1 560.9 550.3 562.3 574.1 568.7 574.3 1882.9 1060.9 1722.6 24.5 4121.3 5337.3 4473.1 3629.9 3843.2 320.9 5257.9 6722.9 541.7 2116.1 2284.9 941.7 100.1 2684.9 2686.7 1217.3 3470.9 2107.4 1845.9 1520.8 2914.9 2334.0 1638.9 2465.7 23.1 4595.8 4411.0 2262.0 1398.1 1765.7 2045.0 2514.8 3040.2 1877.8 2449.5 156.5 25.7 3361.4 1184.0 3417.8 4894.1 1595.8 4527.5 2304.4 2968.6 28.1 3705.1 1155.2 2747.7 13.6 30.9 3218.5 2744.3 2315.1 2374.0 4080.9 2776.5 3992.3 1300.9 435.6 1610.6 4280.8 2712.8 850.7 723.4 3869.4 6022.9 2692.1 3610.9 2182.6 3544.4 4170.3 RPL5 "L5, PPP1R135, uL18" ENSG00000122406 "Ribosomal protein L5" P46777 1 92832013-92841924 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Cancer-related genes, Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA043717, HPA054444" Approved Supported "Nucleoli,Nucleoli rim,Endoplasmic reticulum,Cytosol" NA NA 430000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Nucleoli, Nucleoli rim" "HPA043717: AB_10964719, HPA054444: AB_2732584" "unprognostic (5.81e-3)" "unprognostic (3.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (9.44e-3)" "unprognostic (1.96e-1)" "unprognostic (1.03e-3)" "unprognostic (9.95e-2)" "unprognostic (8.68e-2)" "unprognostic (1.23e-1)" "unprognostic (3.98e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (6.81e-5)" "unprognostic (2.26e-2)" "unprognostic (3.12e-2)" "unprognostic (1.09e-1)" "unprognostic (3.97e-1)" 1236.3 1035.1 515.2 786.9 538.3 1743.3 1798.7 522.4 778.1 1690.1 510.7 1412.8 798.0 1295.2 1388.7 1185.6 1420.7 647.6 890.3 487.5 544.8 858.2 794.9 794.7 1435.7 527.8 511.9 3356.4 2236.0 695.4 869.5 736.1 541.3 1103.1 982.0 346.6 1189.5 847.1 1115.8 1320.8 960.1 962.1 549.0 899.0 1135.5 374.3 528.7 1351.4 1179.5 830.7 1438.8 1309.6 1274.2 552.5 2211.5 924.6 1611.4 1369.2 2045.7 4096.6 2577.6 1283.0 1703.7 1560.0 1108.9 2467.5 933.6 4112.3 2002.9 1451.6 1477.1 1370.3 1871.2 2405.7 1976.3 1314.2 2557.4 2142.3 1402.4 2303.5 2447.2 3322.0 864.6 3382.6 3711.3 1390.4 3027.2 2813.9 2191.6 2129.9 2706.3 2106.7 1814.5 1247.7 2665.7 3741.2 2497.9 1659.1 1724.1 2407.7 3118.5 2702.2 1912.0 1798.7 1367.2 1632.0 836.3 2298.6 3961.6 1316.4 1268.8 4480.6 1345.5 781.6 1429.6 1498.4 2357.4 1290.8 1314.5 2793.5 531.3 2814.4 544.2 234.9 665.6 101.3 758.7 619.1 1520.2 1320.3 1385.5 1151.0 1138.3 1105.7 1729.8 1570.9 56.7 1005.7 552.2 942.7 1140.0 2356.3 515.2 538.3 522.4 778.1 487.5 544.8 527.8 511.9 541.3 549.0 528.7 552.5 1586.8 653.9 1042.2 29.7 3056.7 2843.0 4383.1 2206.0 3168.8 339.6 3182.0 5498.6 375.2 1522.7 1266.7 412.0 89.6 2557.1 2009.8 595.2 1993.7 1697.1 1438.3 840.8 2334.8 1567.8 1236.6 1980.6 35.0 2708.5 4211.6 1464.3 978.1 1009.8 1041.9 2287.9 1546.3 1087.2 1452.5 146.4 33.8 1986.9 720.2 1758.7 2200.6 1189.4 2829.9 1536.8 1406.9 35.6 2171.5 806.3 1969.1 27.2 37.7 1851.6 1567.8 2156.4 2067.8 3935.4 1225.7 2454.6 571.0 298.8 1051.8 2546.2 2122.7 682.8 501.7 3198.9 2893.0 2613.1 2318.2 2797.0 2572.8 3991.1 RPS10 "MGC88819, S10" ENSG00000124614 "Ribosomal protein S10" P46783 6 34417454-34426069 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 4571.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA047268, HPA048084" Approved Approved Cytosol NA NA 130000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA047268: AB_2680007, HPA048084: AB_2680255" "unprognostic (1.92e-1)" "unprognostic (1.54e-1)" "unprognostic (8.21e-2)" "unprognostic (1.78e-1)" "unprognostic (8.92e-3)" "unprognostic (3.79e-2)" "unprognostic (9.72e-3)" "unprognostic (1.93e-2)" "unprognostic (4.30e-3)" "unprognostic (2.04e-1)" "unprognostic (3.59e-1)" "unprognostic (3.82e-1)" "prognostic unfavorable (2.57e-6)" "unprognostic (4.98e-2)" "unprognostic (7.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.45e-1)" 1437.4 1373.5 1054.1 937.6 1054.4 2688.5 2003.3 1013.6 1284.2 1984.1 1022.8 1472.3 919.9 1332.0 1064.3 1995.2 1606.9 756.7 1024.5 1010.7 1034.1 1114.4 1161.4 1006.5 2137.6 1058.2 1024.2 2878.3 2424.5 633.4 929.2 829.4 1051.3 1432.9 916.2 273.2 1532.7 895.2 1419.3 2399.7 1342.9 909.8 1088.6 1538.6 1455.3 558.6 1091.1 1486.2 1090.6 774.4 1696.6 1470.6 1716.1 1069.7 2314.3 1481.2 1486.9 3397.3 2550.1 3757.4 2454.7 1847.4 2604.3 3061.1 2200.4 3633.8 1140.6 4393.3 1873.0 2105.8 1522.9 1688.8 2814.8 3224.9 1840.0 1869.0 5082.5 1974.1 1475.4 3504.8 3492.4 3158.5 2028.2 4156.0 5548.7 2111.2 3977.8 2642.2 2725.4 2459.5 3452.0 2175.2 2327.1 3633.7 2591.3 4761.0 2242.3 5664.1 2144.7 2409.8 1736.7 4221.2 2314.1 2558.9 2492.6 1515.7 1328.4 2213.1 5332.3 1391.5 2878.1 7936.5 1837.0 1338.8 1699.0 1543.5 3072.5 1764.4 4423.0 3815.8 732.4 4092.2 2465.9 746.2 1242.2 378.2 1406.3 996.8 2067.1 2824.8 2408.2 1994.5 1679.6 2732.8 3083.6 2462.3 251.9 1676.0 963.1 1983.5 1767.5 5386.9 1054.1 1054.4 1013.6 1284.2 1010.7 1034.1 1058.2 1024.2 1051.3 1088.6 1091.1 1069.7 597.4 359.0 714.8 0.0 2967.8 1351.9 563.2 354.6 3754.5 62.0 1279.7 1271.1 65.3 1096.6 494.1 263.0 29.2 1497.5 1221.5 911.7 598.7 1451.9 447.1 169.2 282.1 670.4 1232.9 1778.0 0.0 2404.1 1918.4 612.0 1241.6 181.4 589.1 215.5 1258.9 970.6 1034.5 52.2 0.0 2462.2 130.2 1695.5 1330.7 1537.7 849.0 1006.5 633.3 0.0 1923.1 488.6 1562.3 0.0 0.0 1813.3 1843.4 472.4 2267.5 640.3 2166.8 1066.8 284.9 103.5 263.0 652.5 649.4 268.8 270.0 4571.8 1657.0 1454.1 1851.6 284.8 2985.5 573.4 RPS14 "EMTB, S14" ENSG00000164587 "Ribosomal protein S14" P62263 5 150442635-150449739 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018504 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 810000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA018504: AB_1856463" "unprognostic (5.70e-3)" "unprognostic (1.94e-1)" "unprognostic (6.72e-2)" "unprognostic (8.17e-3)" "unprognostic (7.51e-2)" "unprognostic (2.42e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.36e-1)" "unprognostic (1.31e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-1)" "unprognostic (3.26e-1)" "prognostic unfavorable (8.69e-4)" "unprognostic (1.47e-1)" "unprognostic (8.81e-2)" "unprognostic (2.29e-1)" "unprognostic (8.14e-2)" 1391.9 1014.8 819.9 689.6 838.3 1880.5 1567.1 800.3 929.8 1696.9 799.6 1268.2 563.9 1214.3 1001.9 1525.4 1339.5 469.2 1022.8 786.7 832.9 949.3 1027.8 936.0 1126.0 832.7 803.8 2394.3 2431.0 731.9 809.7 636.1 843.8 1228.1 796.4 300.5 1310.9 690.3 1536.8 2210.9 1198.3 684.3 868.0 1343.1 1319.3 344.8 845.6 1142.5 1013.3 1030.0 1170.9 1289.1 1444.9 851.7 1196.9 1768.7 1201.2 2749.6 1497.8 2857.8 1828.0 815.2 1278.2 1298.3 1158.5 2702.9 1799.1 2098.0 1280.9 1583.7 1411.4 1091.9 1548.1 3878.5 782.1 1066.7 2153.7 879.0 1504.7 2171.0 2252.7 2642.0 1164.7 2193.0 1297.4 1441.2 3088.3 1496.2 1933.8 1975.8 1067.3 1250.1 1720.0 2804.7 1499.8 2478.0 1323.5 1935.2 1959.3 1446.0 1134.7 3166.8 2005.3 1827.0 1339.8 1410.9 634.1 3959.4 3109.0 892.6 1703.5 3152.8 1107.3 925.5 711.0 723.0 1229.2 1511.3 1853.6 1722.2 1174.2 2578.4 634.9 2439.8 6736.3 1518.4 6807.8 4685.2 9622.7 14519.2 11377.7 8377.3 7039.4 12461.6 16778.9 11703.6 982.1 6730.0 4055.3 8079.0 8024.6 34303.5 819.9 838.3 800.3 929.8 786.7 832.9 832.7 803.8 843.8 868.0 845.6 851.7 1954.3 1336.5 2464.0 15.0 5469.0 11670.8 9205.1 9468.6 4143.2 501.8 11009.9 13334.3 1873.1 3179.9 4229.9 1478.7 185.6 7225.8 4299.3 2121.7 4527.4 3485.4 1233.0 1626.2 3782.1 3867.8 2390.3 3230.5 23.3 8687.4 8833.9 3287.4 1852.2 2336.3 2293.4 4816.8 4223.5 4186.4 4707.3 203.6 20.0 5595.6 2931.6 5536.1 9991.5 1739.5 4356.7 3703.4 6474.4 21.5 6224.3 2062.0 4655.1 13.0 31.1 5196.5 4753.4 2235.0 3173.0 7998.6 5612.4 5302.3 1902.7 691.9 1604.1 3185.0 5116.9 726.4 815.9 6399.3 15358.6 7126.8 5488.0 4091.6 6155.8 10058.0 RPS15A S15A ENSG00000134419 "Ribosomal protein S15a" P62244 16 18781295-18790383 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047103 Supported NA NA 210000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "HPA047103: AB_10959516" "unprognostic (1.25e-2)" "unprognostic (2.24e-1)" "unprognostic (9.01e-2)" "unprognostic (4.32e-2)" "unprognostic (8.53e-2)" "unprognostic (6.75e-2)" "unprognostic (5.40e-2)" "unprognostic (2.61e-1)" "unprognostic (3.96e-2)" "unprognostic (1.19e-1)" "unprognostic (4.18e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (7.29e-7)" "unprognostic (1.07e-1)" "unprognostic (2.02e-1)" "unprognostic (1.07e-1)" "unprognostic (6.32e-2)" 1970.0 1316.4 740.7 928.8 746.5 3569.4 3976.1 743.0 1047.9 2330.6 756.0 1675.7 847.1 1456.5 1497.7 1966.7 1828.8 966.6 1259.9 724.5 761.8 1225.1 1479.2 1277.8 2624.3 763.7 745.6 3672.5 2825.0 884.7 861.8 1063.8 768.4 1550.5 1291.3 508.4 1888.5 919.1 2290.4 2650.7 1631.3 927.8 766.3 1903.2 1606.5 471.5 753.7 2503.3 1210.8 1847.2 2069.4 1599.0 1979.1 771.8 1665.9 1632.7 2483.5 1708.0 3039.9 5447.7 1905.0 1623.5 2499.0 2223.5 1758.2 2282.2 1828.8 3795.4 3246.5 2258.0 820.6 1567.7 2367.9 3334.7 2557.8 1538.5 4026.8 1666.6 1734.7 5714.8 3899.2 2810.4 1310.7 5282.8 5288.0 1830.6 3782.4 3411.7 2803.0 2251.7 2437.4 2161.9 2389.3 3901.5 2848.5 3593.9 2324.8 2105.3 1704.5 3870.4 2300.4 4873.8 2757.3 1533.9 1781.7 1390.8 1259.1 2592.9 2737.5 1803.4 2342.6 4322.0 2001.0 1037.6 1004.2 1091.0 1617.6 1951.9 2709.1 3415.2 1339.3 2810.8 1215.2 519.8 1342.8 390.9 1643.8 974.2 2426.6 3134.0 2875.1 2323.1 1708.7 2591.0 3584.0 2850.7 215.0 1946.6 909.4 1602.5 2413.8 5373.8 740.7 746.5 743.0 1047.9 724.5 761.8 763.7 745.6 768.4 766.3 753.7 771.8 2629.8 1083.3 1663.6 11.4 6665.9 5978.3 5499.3 3924.8 5776.0 267.9 7331.7 10612.6 72.1 2372.0 2186.7 866.2 100.1 4677.6 4677.4 1392.4 2952.4 1975.3 1210.8 1172.7 3078.3 2808.5 2157.8 4096.4 11.0 3924.4 6676.0 2500.4 2125.4 1458.1 1587.3 3408.3 3436.1 3628.1 3635.3 119.5 11.6 4611.7 1194.2 5381.3 5449.1 622.7 5241.5 3453.2 2995.4 12.2 5190.0 1097.8 5097.9 13.6 16.0 2845.4 3571.7 2307.6 4358.8 5125.0 3359.1 4622.0 964.4 472.3 1393.7 3419.0 2181.1 798.5 662.3 7088.8 7535.8 4526.0 6066.2 2447.3 4984.8 5522.2 RPS17 "MGC72007, RPS17L, RPS17L1, RPS17L2, S17" ENSG00000182774 "Ribosomal protein S17" P08708 15 82536750-82540459 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 5841.9;Extravillous trophoblasts: 6575.5;Prostatic glandular cells: 6309.4;Urothelial cells: 5768.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055060 Approved Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 340000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA055060: AB_2682686" "unprognostic (3.37e-3)" "unprognostic (1.49e-1)" "unprognostic (2.06e-2)" "unprognostic (6.90e-2)" "unprognostic (2.04e-1)" "unprognostic (1.63e-2)" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (4.49e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.83e-1)" "unprognostic (5.40e-2)" "unprognostic (2.09e-1)" "unprognostic (2.31e-1)" 1722.3 1537.3 1226.9 1519.3 1244.9 3816.2 3065.8 1206.6 1768.4 1818.7 1277.0 1724.0 1318.8 1489.3 1967.3 2266.9 1763.0 881.9 1192.2 1197.9 1253.8 1298.7 1646.6 1132.3 2832.4 1261.6 1218.6 3571.4 3388.7 859.1 987.5 1099.1 1264.1 1418.3 1477.9 477.2 2051.9 967.4 1588.9 2566.0 1319.4 1188.3 1265.4 1560.6 1555.5 375.1 1245.4 2012.1 1216.9 1063.5 2563.2 1567.2 1790.5 1281.2 3535.7 4567.8 3027.7 2844.3 3850.6 6013.0 3418.3 3504.2 3142.7 2924.3 2235.3 5420.6 3683.5 5561.4 3680.3 3142.1 2276.7 4963.3 6162.5 4765.3 2251.9 4262.2 8647.1 3224.4 5009.5 4698.1 5817.4 4197.2 2100.2 5478.2 7877.0 1959.5 6027.1 4520.5 3281.1 3993.8 3909.8 4288.1 3200.3 6205.4 3467.9 7403.5 4567.2 4224.9 2885.2 3333.8 3746.8 4676.4 3425.9 6945.5 2678.6 3325.2 2101.9 4289.8 9110.0 3205.5 3707.5 10012.4 2932.1 2388.1 3534.7 2353.9 6119.2 3312.3 7992.5 5635.5 2580.9 8286.2 2335.3 519.6 1072.5 302.9 1155.2 949.1 1830.0 2371.9 1954.3 1477.4 1685.5 2173.6 2280.0 1986.3 148.5 1335.8 859.0 1700.9 1707.8 3337.5 1226.9 1244.9 1206.6 1768.4 1197.9 1253.8 1261.6 1218.6 1264.1 1265.4 1245.4 1281.2 118.0 814.1 1488.0 8.1 1824.1 43.2 5841.9 11.0 675.6 83.2 1696.6 859.5 428.3 2093.2 1039.5 176.6 50.1 3419.1 1523.2 487.4 545.9 1846.4 75.5 269.9 496.3 1390.0 963.5 1971.9 5.5 3041.8 6575.5 973.4 375.1 305.1 937.3 67.5 2470.1 3241.0 2716.5 42.1 6.3 2545.9 2.0 3330.0 46.3 229.6 4400.2 1201.6 30.2 7.5 3519.0 296.5 3137.0 6.0 10.1 2490.2 2021.5 1873.5 547.9 6309.4 1840.9 1036.8 504.2 121.4 1183.3 2746.2 689.9 611.9 701.6 1140.4 63.9 3414.9 1379.0 53.7 3448.3 5768.6 RPS19 "DBA, eS19, LOH19CR1, S19" ENSG00000105372 "Ribosomal protein S19" P39019 19 41860255-41872925 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063217 Supported Nucleoplasm NA NA 260000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Nucleoplasm "HPA063217: AB_2732699" "unprognostic (8.02e-3)" "unprognostic (9.04e-2)" "unprognostic (5.93e-2)" "unprognostic (1.14e-1)" "unprognostic (7.32e-3)" "unprognostic (1.32e-1)" "unprognostic (2.69e-2)" "unprognostic (9.14e-2)" "unprognostic (1.06e-1)" "unprognostic (6.68e-2)" "unprognostic (5.78e-2)" "unprognostic (9.96e-2)" "prognostic unfavorable (2.32e-8)" "unprognostic (1.16e-1)" "unprognostic (7.55e-2)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" 1929.6 1900.6 1567.9 1417.3 1592.2 2933.3 2052.3 1529.9 2038.1 2531.8 1544.4 2004.3 1389.8 1628.2 679.3 3488.9 2151.1 766.0 1349.4 1501.4 1560.9 1424.1 2262.6 1640.4 2271.7 1631.4 1548.2 3787.9 3981.7 585.6 1015.9 818.9 1606.1 2231.8 1105.1 370.4 1748.9 760.8 1573.4 3885.1 2168.6 767.5 1626.1 2909.0 2099.7 639.3 1585.0 1825.5 1516.5 728.6 1869.1 2025.4 2512.4 1619.6 3536.2 4978.2 3109.1 2770.4 3924.8 5205.4 3456.4 2731.6 3132.5 3378.6 2982.1 3854.2 2341.3 5185.2 2985.2 2483.1 1670.6 1819.8 2701.4 4647.3 1563.5 2183.2 5098.9 2626.1 1471.5 4029.3 6775.6 4355.4 2564.0 7419.1 8959.5 2132.0 3942.4 5453.7 3421.0 4849.8 2911.6 3476.5 2845.7 4010.8 3975.9 3021.3 3619.2 9954.1 2087.6 4372.0 2503.1 2511.1 3188.1 3714.9 2216.7 2693.9 1539.3 4915.7 3951.2 4649.7 2787.7 6840.6 2694.1 2157.5 3396.5 1451.9 4383.8 3886.3 4520.6 5054.3 2348.3 3672.5 2498.9 1309.9 5303.2 586.8 9147.6 9536.3 13783.0 18138.6 13464.4 11872.3 8174.5 17813.4 15114.7 13788.0 724.9 12054.7 12053.9 11257.8 11367.1 30500.3 1567.9 1592.2 1529.9 2038.1 1501.4 1560.9 1631.4 1548.2 1606.1 1626.1 1585.0 1619.6 2154.8 1644.2 2318.8 17.6 7536.2 13338.7 9463.4 12098.6 8008.7 295.5 11387.2 17068.7 680.0 2778.1 4886.7 1430.8 127.2 6635.1 4648.2 1753.9 2641.3 4446.2 482.4 1178.2 3145.6 3665.9 2227.6 2708.0 15.4 8576.4 9609.3 2834.8 2442.4 1645.3 1825.2 4566.6 3793.4 3258.5 4591.9 136.3 20.2 4777.7 3497.2 6041.3 8631.8 1752.6 4036.7 4053.7 4557.0 52.5 5989.0 991.8 4541.7 13.6 42.4 7669.3 4181.6 1892.7 4036.1 8714.9 4183.2 3284.5 1889.5 479.3 1584.3 3428.0 5508.3 608.5 1952.5 7919.1 16952.4 6534.4 6030.8 3718.5 6131.8 8160.5 RPS24 "eS24, S24" ENSG00000138326 "Ribosomal protein S24" P62847 10 78033760-78056813 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA003364, HPA073508" Approved Enhanced "Endoplasmic reticulum,Cytosol" NA NA 90000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA003364: AB_1079847, HPA073508: " "prognostic favorable (1.50e-4)" "unprognostic (1.58e-1)" "unprognostic (4.95e-2)" "unprognostic (1.09e-1)" "unprognostic (6.95e-2)" "unprognostic (8.01e-3)" "unprognostic (3.64e-2)" "unprognostic (1.16e-1)" "unprognostic (1.25e-1)" "unprognostic (9.48e-2)" "unprognostic (1.10e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.10e-10)" "unprognostic (3.18e-2)" "unprognostic (1.38e-1)" "unprognostic (6.65e-2)" "unprognostic (8.22e-2)" 2458.4 1993.8 1538.1 1424.8 1549.0 4673.1 4757.9 1530.6 2756.8 3012.3 1536.9 2576.1 1756.5 2519.4 2811.2 2293.7 2474.3 1606.6 1604.1 1488.8 1645.6 1754.0 2209.3 1458.8 2669.4 1576.3 1569.3 5844.6 2955.3 1438.5 1178.1 1754.5 1586.4 1958.8 2573.9 964.5 2512.4 1637.4 3019.3 3045.0 1693.7 1946.0 1586.5 1916.9 1651.7 776.1 1538.2 2798.0 2252.7 2553.7 2707.5 2652.8 2547.2 1623.3 3390.5 1308.2 3303.3 5221.9 4021.6 7048.4 2884.3 3654.6 5055.0 3773.7 3323.4 1878.5 2339.0 7039.0 1940.5 3205.9 1303.4 2612.8 3847.7 4674.9 3460.7 2403.0 4325.8 2868.1 822.8 1879.0 4533.9 6943.1 1575.6 6732.0 6867.2 2652.4 9675.7 7591.6 4592.2 2981.8 4007.0 1455.6 4191.8 1388.2 3770.5 11229.0 2318.2 5976.0 12085.6 2567.9 3934.7 3482.3 4773.4 1608.2 1658.6 3234.9 1805.2 6010.8 4716.9 3414.2 3356.5 7559.6 3894.3 1175.5 2712.7 1570.9 4896.7 1774.5 3875.7 5354.8 1459.5 9444.0 970.5 1058.0 2124.4 809.3 1585.0 2036.3 2627.9 2796.4 2178.6 2037.5 2932.4 2380.3 2861.9 2644.0 276.9 2801.9 1626.7 2569.0 1916.3 4390.5 1538.1 1549.0 1530.6 2756.8 1488.8 1645.6 1576.3 1569.3 1586.4 1586.5 1538.2 1623.3 2643.8 743.6 1535.6 44.1 4070.7 4105.7 5007.7 2774.6 5333.8 344.3 4139.9 6421.4 617.1 2051.8 1719.2 801.9 108.4 3406.3 3424.5 1200.3 3279.1 2335.3 1414.9 1799.8 4602.7 2194.2 2090.5 3250.6 40.4 4508.1 6260.1 2099.8 2310.4 2451.6 1237.2 3541.5 2346.6 2252.0 3311.9 151.4 42.6 3944.5 880.9 4754.9 4734.0 5440.1 5670.8 3861.9 2031.3 49.6 5590.7 1395.6 3262.7 23.1 45.9 2886.9 3231.4 2588.2 3109.6 4622.7 2703.3 3770.5 768.5 465.7 1268.8 3609.7 2661.0 653.8 709.0 7289.7 4590.1 3541.8 3518.7 4105.6 4384.9 4943.2 RPS26 "eS26, S26" ENSG00000197728 "Ribosomal protein S26" P62854 12 56041351-56044697 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "ovarian cancer: 494.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA043961, HPA055803" Uncertain Enhanced "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA043961: AB_10963579, HPA055803: AB_2682927" "unprognostic (1.59e-1)" "unprognostic (1.40e-1)" "unprognostic (3.36e-1)" "unprognostic (9.58e-2)" "unprognostic (3.74e-1)" "unprognostic (7.84e-3)" "unprognostic (1.53e-1)" "unprognostic (1.65e-1)" "unprognostic (2.25e-1)" "unprognostic (3.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.03e-1)" "unprognostic (2.06e-2)" "unprognostic (1.41e-1)" "unprognostic (4.40e-2)" "unprognostic (2.18e-1)" "unprognostic (7.99e-2)" 720.5 1265.1 387.6 271.7 388.8 395.5 690.2 382.8 480.4 707.7 384.0 731.2 177.1 569.7 410.7 875.4 724.0 123.3 713.0 380.9 416.6 701.8 926.6 521.9 512.9 396.3 399.7 1120.6 1170.2 274.3 476.7 251.6 389.9 627.3 403.3 69.8 592.3 335.9 778.2 857.3 744.1 307.2 383.4 832.0 717.5 208.8 394.0 616.8 544.1 390.6 715.6 734.3 698.0 389.2 639.2 763.3 853.6 319.5 1153.3 1696.4 852.0 633.4 929.5 1027.7 596.0 1182.7 281.7 1408.3 383.5 670.6 339.5 293.2 970.5 544.0 698.1 558.9 1552.8 743.9 482.1 719.0 1062.3 490.5 392.2 1036.9 1705.6 544.3 614.0 404.0 794.3 989.6 517.2 458.1 845.1 983.2 371.8 886.0 839.7 766.7 1710.8 496.7 254.8 884.3 871.4 634.9 318.2 552.4 245.8 542.2 372.2 252.1 479.4 538.6 260.8 255.0 524.3 328.0 518.0 369.3 810.2 770.9 284.0 969.2 334.4 334.8 394.8 262.5 650.7 410.2 723.2 872.3 841.4 711.8 508.4 720.3 898.4 863.6 154.8 607.5 373.0 643.6 963.7 1264.1 387.6 388.8 382.8 480.4 380.9 416.6 396.3 399.7 389.9 383.4 394.0 389.2 1114.5 224.4 237.7 5.2 2483.4 1760.6 852.7 2533.9 3266.8 131.0 1968.1 2542.2 29.2 1425.5 985.7 430.4 62.6 1237.2 1377.0 1803.5 972.4 1031.5 85.4 862.0 876.0 992.0 860.5 1977.9 5.2 2625.0 2835.4 1006.2 1666.7 861.2 514.4 1242.7 1647.4 2125.4 1369.2 75.7 5.1 1406.6 732.4 1557.8 1925.7 57.3 295.4 1146.8 1462.1 6.5 754.7 706.4 563.4 6.6 7.1 1806.8 1756.4 221.5 2590.7 1221.2 2448.3 1503.0 557.4 193.1 309.0 719.1 935.9 305.9 304.0 4236.6 1814.2 1708.2 2103.6 1318.5 1411.0 1000.6 RPS27 "MPS-1, MPS1, S27" ENSG00000177954 "Ribosomal protein S27" P42677 1 153990762-153992155 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA066851 Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA066851: AB_2685737" "prognostic favorable (9.69e-4)" "unprognostic (1.40e-1)" "unprognostic (2.34e-1)" "unprognostic (1.35e-1)" "unprognostic (1.01e-2)" "unprognostic (1.28e-1)" "unprognostic (8.62e-2)" "unprognostic (5.88e-3)" "unprognostic (2.05e-2)" "unprognostic (5.04e-2)" "unprognostic (2.55e-2)" "unprognostic (6.81e-2)" "prognostic unfavorable (4.86e-7)" "unprognostic (1.53e-1)" "unprognostic (1.71e-1)" "unprognostic (2.44e-1)" "unprognostic (8.81e-2)" 5616.3 3455.2 3594.8 2840.3 3661.4 7200.5 8666.0 3567.1 5829.2 7430.2 3632.2 5066.8 1888.2 4501.2 4042.3 4706.9 5856.4 2273.3 3532.4 3573.6 3695.5 4491.5 3641.9 4076.2 7137.0 3672.3 3637.9 12404.9 7506.0 3141.5 3807.8 2215.5 3648.3 5395.9 3581.3 1411.8 4351.2 3444.9 4963.3 7568.0 5438.8 2777.4 3605.2 6878.7 5028.9 1668.1 3632.1 8478.3 4692.8 4124.9 9185.3 5497.1 5730.0 3661.3 3446.4 3986.5 5147.0 2805.0 11901.1 11649.6 3148.9 4096.1 9832.9 5421.0 4866.7 8059.8 3705.0 7817.4 3304.5 6009.8 1792.6 3390.5 4624.1 6847.5 4577.2 3804.0 5945.0 3090.0 5442.0 5323.3 7881.7 6945.8 3888.2 11426.5 13193.2 4334.0 7920.5 8011.4 4546.6 6426.6 3865.0 4112.2 5239.5 8711.2 7513.7 4328.1 6227.9 11540.0 5775.4 4735.7 3753.2 6114.5 5064.7 6938.6 2702.3 5977.7 2340.0 8120.1 7572.9 6970.2 4531.0 13542.1 2672.3 1841.0 3043.3 2963.9 4141.0 8191.3 9166.7 9585.2 3202.5 3805.3 2591.7 12942.7 11463.1 5536.5 28801.5 11225.6 34790.5 56947.7 43040.6 37135.0 13993.9 48738.8 53667.4 42304.0 2458.8 27662.5 10603.9 23115.6 32257.9 76381.9 3594.8 3661.4 3567.1 5829.2 3573.6 3695.5 3672.3 3637.9 3648.3 3605.2 3632.1 3661.3 3187.7 2201.9 3978.4 11.4 13562.6 12494.3 5398.2 7693.2 4868.2 411.9 6937.5 6570.1 939.8 5752.0 4175.1 2155.5 193.9 6037.3 9149.7 2192.5 4431.5 4142.9 2927.6 1809.2 4392.1 3779.0 3022.4 4789.2 5.4 10431.2 6808.0 4116.6 2102.4 2597.5 4306.7 4628.6 6451.6 8222.0 4303.1 191.8 6.0 6849.8 1953.1 9173.5 14035.0 10184.0 7097.1 4890.7 5914.2 5.6 9465.8 1961.9 9527.4 3.0 6.8 6134.0 5941.1 3543.1 3703.6 4365.2 6412.1 6526.1 1955.9 646.0 2734.7 5847.6 4188.0 1563.3 1638.3 4859.8 14322.5 6382.1 11013.6 1757.5 6839.1 4530.7 RPS28 "eS28, S28" ENSG00000233927 "Ribosomal protein S28" P62857 19 8321158-8323340 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast myoepithelial cells: 19765.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047132 Approved Approved Cytosol NA NA 730000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Cytosol "HPA047132: AB_10962147" "unprognostic (3.47e-2)" "unprognostic (7.47e-3)" "unprognostic (1.49e-1)" "prognostic favorable (2.47e-4)" "unprognostic (3.09e-2)" "unprognostic (2.84e-3)" "unprognostic (2.16e-1)" "unprognostic (6.34e-2)" "unprognostic (1.56e-1)" "unprognostic (3.61e-2)" "unprognostic (2.80e-2)" "unprognostic (2.19e-2)" "unprognostic (3.22e-1)" "unprognostic (1.17e-1)" "unprognostic (1.40e-2)" "unprognostic (8.82e-2)" "unprognostic (1.81e-2)" 227.9 202.9 129.8 113.7 134.6 286.7 226.8 128.6 189.9 226.5 130.2 188.9 127.8 147.3 52.5 328.4 172.3 94.9 213.0 124.0 129.7 184.6 247.5 171.0 220.2 132.2 129.3 313.0 432.4 72.1 162.7 88.2 129.5 211.1 47.8 20.3 227.8 60.6 252.9 353.8 197.1 42.6 134.1 273.4 219.4 55.7 138.6 117.3 177.4 80.8 98.0 176.7 240.0 131.6 245.9 97.7 86.6 197.5 122.3 183.2 136.6 156.9 141.7 177.6 144.5 133.2 104.7 364.4 189.3 91.7 75.9 183.0 114.9 269.0 25.6 223.2 772.6 176.4 110.4 134.5 219.6 204.6 188.5 294.9 303.7 129.7 116.4 110.9 165.2 279.0 251.6 402.9 80.2 152.5 314.8 725.0 260.8 141.4 587.2 222.7 92.9 390.9 118.6 115.5 165.7 162.3 112.7 206.7 289.3 27.6 157.0 340.9 210.4 147.0 125.1 288.1 266.5 468.3 265.8 248.1 155.7 389.3 101.2 21.3 61.7 13.2 54.5 39.3 76.6 105.0 88.5 64.5 55.9 90.7 98.9 70.0 8.8 44.6 36.3 98.0 61.0 166.2 129.8 134.6 128.6 189.9 124.0 129.7 132.2 129.3 129.5 134.1 138.6 131.6 4308.7 1458.3 2798.6 9.8 6575.7 7900.9 4267.0 4952.1 5103.9 484.0 11594.7 19765.7 382.7 3044.0 2801.5 1340.8 296.1 3851.9 4608.0 2028.0 3335.8 3189.3 262.2 1687.9 4074.7 3610.1 2654.0 3550.8 7.4 7271.1 4542.0 2535.5 2746.2 2586.9 1954.3 4062.9 5016.7 5562.8 4537.9 267.5 9.3 5334.5 1287.8 5745.6 5979.8 559.6 3915.0 3716.8 3523.6 21.5 5150.0 1694.4 3560.3 6.6 14.5 5090.4 4152.6 1644.9 4225.1 3830.4 4316.3 5555.1 1153.6 729.0 1084.7 3477.1 2508.7 367.9 953.1 7848.6 10873.6 4244.9 5017.4 2121.3 5894.5 4043.4 RPS29 "S29, uS14" ENSG00000213741 "Ribosomal protein S29" P62273 14 49570984-49599164 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA004107 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA004107: AB_1079848" "prognostic favorable (2.66e-4)" "unprognostic (1.38e-1)" "unprognostic (1.38e-1)" "unprognostic (1.28e-1)" "unprognostic (4.40e-3)" "unprognostic (4.13e-2)" "unprognostic (9.95e-2)" "unprognostic (4.21e-2)" "unprognostic (2.98e-2)" "unprognostic (1.12e-1)" "unprognostic (8.62e-2)" "unprognostic (1.18e-1)" "unprognostic (2.94e-1)" "unprognostic (3.18e-2)" "unprognostic (1.66e-1)" "unprognostic (7.48e-3)" "unprognostic (7.71e-2)" 2915.6 2346.5 1747.8 1549.0 1785.8 3286.7 3207.7 1739.1 2601.7 3116.1 1718.3 2990.1 1407.8 1886.3 910.5 3294.5 2641.4 401.1 2127.4 1719.9 1762.6 2371.4 2697.6 2200.4 2364.9 1769.5 1741.7 4756.3 4388.2 1049.0 1483.6 887.0 1779.0 2246.8 1122.6 586.1 2625.0 797.7 3625.5 4604.2 3272.8 594.9 1830.7 4088.6 2645.0 1036.8 1800.8 3083.3 1906.9 1770.0 2079.7 2435.8 2777.8 1817.5 3057.7 1984.5 2021.5 1823.8 2271.9 3830.2 2675.3 2042.2 1722.2 1821.1 1483.1 2020.7 2733.7 2772.5 2264.9 1729.0 895.7 2605.0 2373.0 2922.0 2014.3 1811.3 4267.9 2191.4 1630.4 3564.5 2776.6 5612.2 1803.4 4011.6 4623.6 1204.7 3464.6 3181.7 2623.2 4723.4 2489.2 3498.4 1791.5 4047.4 3845.0 3454.4 2484.9 5075.2 5572.2 3178.5 2521.0 3196.6 2248.6 2696.4 1527.3 1753.1 1455.4 2636.2 5088.5 1938.5 3444.4 4786.4 2459.7 1381.7 3726.2 1295.6 1836.9 4014.0 4872.1 3856.3 973.0 2256.8 1363.0 3144.8 4379.9 1967.1 6689.0 3436.4 8449.9 11659.9 12162.6 8749.3 5025.2 10334.9 13471.6 11360.1 968.3 5389.4 3185.1 6778.8 7617.0 26592.8 1747.8 1785.8 1739.1 2601.7 1719.9 1762.6 1769.5 1741.7 1779.0 1830.7 1800.8 1817.5 1348.6 1131.4 2051.0 7.8 5426.0 3418.6 1043.1 2689.6 672.1 235.2 4463.4 3147.6 609.1 2805.3 2104.4 1074.1 129.3 3390.8 4425.2 2370.0 2424.1 2731.6 1371.1 1272.1 2960.5 1727.4 2673.2 2790.5 10.7 7061.8 4966.0 1443.2 650.3 1997.1 3019.4 2592.2 4092.8 7356.4 3048.0 107.7 12.0 6874.6 769.0 5623.6 5164.4 3280.3 3747.1 2396.2 2002.8 10.3 4580.9 1122.2 5206.1 10.1 17.9 5207.4 5628.6 1617.8 1584.1 1084.2 4951.5 3523.5 985.2 355.1 1091.3 1292.9 1159.9 1090.2 994.1 1255.0 4894.6 3673.2 4742.9 954.8 6917.3 1177.5 RPS7 "eS7, S7" ENSG00000171863 "Ribosomal protein S7" P62081 2 3575260-3580920 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056586 Approved Approved "Endoplasmic reticulum,Cytosol" NA Yes 820000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA056586: AB_2683179" "unprognostic (3.28e-3)" "unprognostic (1.85e-1)" "unprognostic (7.07e-2)" "unprognostic (2.29e-1)" "unprognostic (3.00e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (5.27e-4)" "unprognostic (6.41e-2)" "unprognostic (6.02e-3)" "unprognostic (7.08e-2)" "unprognostic (5.60e-2)" "unprognostic (6.27e-2)" "prognostic unfavorable (1.34e-8)" "unprognostic (3.70e-2)" "unprognostic (2.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.55e-1)" 1083.4 764.7 778.0 774.7 787.2 2152.4 2194.5 772.7 1112.6 1124.8 800.2 1044.1 766.0 867.6 1309.0 1281.8 1152.1 642.5 744.5 755.7 779.1 925.4 1082.6 717.6 1622.5 785.1 770.8 2394.6 1624.1 725.0 686.2 939.7 784.8 887.8 1166.3 603.2 1213.7 697.3 906.5 1419.8 866.8 895.3 805.3 964.6 1011.3 396.3 795.7 1665.6 797.7 843.0 1841.7 1038.2 1063.0 798.4 1235.6 1178.5 1778.9 1923.5 1725.8 3754.0 2913.5 1458.3 2527.9 2370.8 1371.5 2053.4 1890.4 4081.0 2369.1 1697.7 1646.1 1321.0 2038.5 2370.0 2077.4 1289.4 2743.3 1496.8 758.2 2998.2 4156.0 2622.8 1489.1 3183.4 3497.5 1475.1 3176.3 2552.1 2816.8 3707.9 2356.3 2015.2 2433.4 1661.0 2930.2 5815.8 2638.6 3679.7 1810.5 2300.9 1812.6 3670.5 2725.7 1487.1 2016.6 3028.5 771.7 2931.1 4670.0 1487.2 1615.3 3727.3 1327.2 1415.1 931.1 987.9 2387.5 2240.1 4420.9 4079.3 1489.6 3113.0 1617.9 337.1 656.8 243.1 808.8 570.7 1192.3 1411.3 1159.2 1036.9 1063.6 1172.7 1254.6 1132.2 129.3 1032.8 553.2 1016.6 1083.5 2065.3 778.0 787.2 772.7 1112.6 755.7 779.1 785.1 770.8 784.8 805.3 795.7 798.4 2544.8 496.8 793.2 28.1 3845.5 3923.3 4252.7 2961.9 3989.5 401.5 4245.2 7977.4 154.5 1720.0 1620.6 647.4 325.2 3627.9 2815.0 730.8 2606.1 2129.9 1517.5 1255.0 3316.9 1997.7 1250.9 2352.4 33.5 3434.0 5702.2 1854.2 1378.2 1489.1 1171.5 2855.2 2067.5 1515.6 2338.1 141.3 37.2 2244.0 929.8 2534.9 3126.0 485.1 2927.6 2110.0 2001.1 50.6 3250.8 1257.2 2634.4 27.6 49.8 2878.9 1747.3 1748.6 2572.7 4420.1 1233.7 4372.3 847.1 741.6 1452.9 1699.5 3261.7 1248.6 775.4 4912.8 5050.7 3716.9 3078.6 3673.3 2604.1 4351.5 RUNX1 "AML1, AMLCR1, CBFA2, PEBP2A2" ENSG00000159216 "RUNX family transcription factor 1" Q01196 21 34787801-36004667 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 175.5;Glandular and luminal cells: 155.8;Microglial cells: 195.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 23.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 23.9" "Cell line enhanced" "Detected in many" "HEL: 251.3;HMC-1: 145.3;JURKAT: 226.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA004176, HPA037912" Enhanced Enhanced Nucleoplasm,Vesicles No No "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Vesicles "HPA004176: AB_1078412, HPA037912: AB_2675733" "unprognostic (4.06e-3)" "unprognostic (2.35e-2)" "unprognostic (1.42e-2)" "unprognostic (1.52e-1)" "unprognostic (5.15e-3)" "unprognostic (2.62e-1)" "unprognostic (5.87e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.12e-3)" "unprognostic (2.33e-2)" "unprognostic (3.47e-2)" "prognostic unfavorable (3.44e-15)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (6.17e-2)" "unprognostic (5.47e-2)" 14.8 3.8 2.9 20.3 2.1 45.5 27.1 2.6 4.0 15.3 5.1 6.7 5.1 3.3 3.1 9.2 4.7 16.0 6.3 2.8 3.2 4.6 7.0 22.4 11.3 6.0 4.3 6.3 4.0 1.5 5.1 8.5 6.5 13.5 6.5 0.3 39.2 3.5 18.9 11.6 6.8 9.2 4.9 10.2 16.9 3.8 9.1 28.2 4.8 1.4 9.9 20.8 12.8 7.9 50.9 3.8 0.1 0.3 12.5 16.0 32.0 28.1 28.4 15.3 11.6 2.5 37.7 24.9 1.8 24.9 25.5 45.0 3.0 33.6 21.4 38.7 3.8 251.3 10.1 11.6 22.9 29.4 145.3 30.9 19.8 46.6 45.6 21.2 8.8 226.3 17.3 14.1 32.7 10.7 119.3 46.5 2.2 27.4 14.5 119.2 84.6 15.3 20.7 19.9 1.4 0.0 28.9 7.2 10.5 6.8 14.7 67.8 37.0 25.1 32.4 37.8 42.8 46.4 20.7 23.3 31.2 63.4 37.4 23.9 3.1 7.1 3.4 1.4 3.2 4.1 3.0 3.2 0.9 3.6 4.5 3.7 3.4 1.5 4.7 3.4 4.5 2.2 2.9 2.1 2.6 4.0 2.8 3.2 6.0 4.3 6.5 4.9 9.1 7.9 6.2 54.5 35.4 1.6 27.0 41.6 52.7 61.2 54.7 2.3 175.5 94.6 3.2 28.6 60.8 20.2 0.0 2.1 39.5 18.7 1.9 39.7 19.4 89.6 21.5 9.2 6.0 47.3 3.5 28.1 21.4 49.2 84.6 155.8 17.7 29.2 4.6 5.4 68.4 0.0 3.2 12.4 28.5 77.0 122.5 27.1 4.7 84.4 28.4 195.8 42.2 0.5 39.1 1.5 1.6 101.0 15.8 4.5 27.7 43.6 8.3 1.6 78.6 0.8 0.0 111.3 51.2 29.0 28.0 53.7 20.2 2.5 41.6 2.7 17.0 75.3 SEC23B "CDA-II, CDAII, CDAN2, HEMPAS" ENSG00000101310 "SEC23 homolog B, COPII coat complex component" Q15437 20 18507520-18561415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008216, HPA069974" Uncertain Supported Vesicles NA Yes 16000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA008216: AB_1079895, HPA069974: AB_2686223" "unprognostic (4.47e-2)" "unprognostic (2.67e-2)" "unprognostic (3.52e-1)" "prognostic favorable (8.25e-4)" "unprognostic (1.24e-1)" "unprognostic (1.33e-1)" "unprognostic (5.44e-3)" "unprognostic (6.01e-2)" "unprognostic (1.39e-1)" "unprognostic (8.75e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-2)" "unprognostic (3.91e-2)" "unprognostic (1.72e-2)" "unprognostic (4.26e-2)" "unprognostic (2.81e-2)" "unprognostic (8.21e-2)" 19.6 38.3 18.7 32.0 27.1 36.0 37.8 24.7 25.9 36.2 27.4 31.6 23.8 17.2 53.8 28.4 29.5 23.1 8.5 19.5 22.4 37.4 30.6 29.7 30.5 27.2 23.8 16.9 57.1 50.6 32.6 24.2 27.2 34.8 32.7 40.7 70.9 35.9 4.1 18.2 23.3 18.5 24.5 25.5 38.2 34.8 23.2 27.6 59.5 6.2 38.0 30.5 12.6 38.9 85.0 93.9 49.8 48.7 32.3 36.6 116.0 69.8 45.3 80.0 68.7 84.9 73.8 37.5 44.9 50.4 107.0 88.5 88.5 120.7 86.2 47.5 43.1 64.9 35.6 130.6 70.5 90.2 78.7 28.0 71.8 118.0 151.4 47.6 50.6 34.0 74.8 82.4 55.1 90.7 59.8 49.5 48.0 118.9 101.6 62.4 77.7 122.1 83.0 85.6 78.8 58.0 83.6 188.9 80.6 62.6 82.3 94.4 45.3 53.1 29.8 58.4 87.1 104.2 155.9 60.1 45.3 47.8 74.4 147.9 94.1 106.0 57.2 95.6 78.7 67.2 56.8 61.4 107.9 61.2 51.3 54.0 48.0 78.8 94.9 80.7 75.4 103.7 18.7 27.1 24.7 25.9 19.5 22.4 27.2 23.8 27.2 24.5 23.2 38.9 8.5 16.0 43.5 15.3 24.7 11.5 21.0 34.3 10.2 21.0 21.5 15.6 3.0 20.0 42.5 31.3 16.7 34.3 36.0 26.2 58.7 36.1 95.6 25.4 12.4 11.3 19.7 7.4 17.9 33.4 30.0 11.7 25.0 31.3 15.9 13.6 11.0 25.6 42.9 13.5 20.5 34.7 26.4 38.7 21.0 11.3 14.3 30.3 23.2 15.0 33.1 23.9 9.2 23.1 27.0 31.8 24.2 10.5 59.0 30.1 11.8 53.2 45.4 20.4 19.7 12.4 12.2 48.7 22.1 15.8 14.2 65.8 21.0 16.0 21.5 28.3 SERPINC1 "AT3, ATIII, MGC22579" ENSG00000117601 "Serpin family C member 1" P01008 1 173903800-173917327 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1341 "liver: 5056.6" "Cell type enriched" "Detected in some" 49 "Hepatocytes: 2707.9" "Cancer enriched" "Detected in some" 871 "liver cancer: 1504.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 37 "Hep G2: 84.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001816, CAB016790, HPA024007" Supported "Secreted to blood" NA NA 120000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB016790: , HPA001816: AB_1079926, HPA024007: AB_1856732" "unprognostic (1.28e-2)" "unprognostic (2.22e-1)" "unprognostic (3.83e-2)" "unprognostic (5.98e-2)" "unprognostic (6.91e-2)" "unprognostic (1.93e-2)" "prognostic favorable (3.40e-5)" "unprognostic (1.75e-2)" "unprognostic (8.67e-2)" "unprognostic (3.48e-2)" "unprognostic (4.74e-2)" "unprognostic (1.91e-1)" "unprognostic (2.36e-2)" "unprognostic (5.28e-3)" "unprognostic (5.80e-2)" "unprognostic (6.35e-2)" "unprognostic (8.21e-2)" 0.3 0.1 0.2 0.0 0.3 0.0 0.1 0.3 0.3 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.3 0.3 0.2 3.7 5056.6 0.3 0.1 0.3 0.2 0.1 0.2 0.0 0.2 0.1 0.3 0.1 0.0 0.7 0.1 0.0 0.3 0.1 0.2 0.0 0.2 1.5 0.2 0.4 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 84.2 0.0 1.6 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.2 1.8 0.1 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.0 1.0 0.1 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.3 0.2 0.3 0.2 0.3 0.2 0.2 0.3 0.1 3.2 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 37.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.0 1.6 0.0 34.7 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.1 42.1 2707.9 0.2 0.0 0.1 0.0 0.0 55.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 4.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.3 3.7 0.0 0.0 0.2 SERPIND1 "D22S673, HC-II, HC2, HCF2, HLS2" ENSG00000099937 "Serpin family D member 1" P05546 22 20774113-20787720 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Chemotaxis, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 1253.1" "Cell type enriched" "Detected in some" 25 "Hepatocytes: 283.7" "Cancer enriched" "Detected in many" 80 "liver cancer: 334.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "Hep G2: 208.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB008639, HPA055767" Supported Approved Vesicles "Secreted to blood" NA NA 50000000000 "Cluster 24: B-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB008639: AB_1618010, HPA055767: AB_2682912" "unprognostic (1.68e-1)" "unprognostic (8.27e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.09e-4)" "unprognostic (5.42e-2)" "unprognostic (1.23e-1)" "unprognostic (1.12e-3)" "unprognostic (1.56e-1)" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (2.88e-1)" "unprognostic (3.94e-9)" "unprognostic (2.01e-1)" "unprognostic (4.66e-2)" "unprognostic (8.36e-3)" "unprognostic (1.46e-1)" 0.3 0.2 0.1 0.0 0.8 0.2 0.4 1.7 0.8 1.0 87.7 0.0 0.0 2.0 0.0 0.1 0.9 0.4 1.1 1.7 0.0 0.3 1253.1 2.5 0.0 0.0 0.0 1.8 0.5 10.1 0.8 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.2 0.0 0.2 0.4 0.1 0.2 0.0 0.7 0.0 0.0 0.8 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 208.2 0.1 0.8 0.5 0.1 0.0 1.6 0.0 0.0 20.4 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 2.4 16.5 0.0 0.7 0.0 0.0 3.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.1 0.0 0.1 0.1 0.0 0.2 7.2 0.2 13.9 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.1 0.3 0.0 0.5 0.1 0.0 0.1 0.8 1.7 0.8 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 11.3 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 2.7 1.6 0.0 0.1 2.3 0.0 0.0 1.3 0.0 3.9 283.7 0.1 0.0 0.9 0.0 0.0 6.3 0.0 0.0 1.2 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.5 3.4 0.0 0.0 SERPINE1 "PAI, PAI1, PLANH1" ENSG00000106366 "Serpin family E member 1" P05121 7 101127104-101139247 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 418.0" "Cell type enhanced" "Detected in many" "Endothelial cells: 165.1;Fibroblasts: 162.1;Pancreatic endocrine cells: 231.8;Smooth muscle cells: 239.3;Syncytiotrophoblasts: 651.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "NK-cell: 9.5" "Lineage enriched" "Detected in single" 20 "NK-cells: 9.5" "Cell line enhanced" "Detected in many" "BJ: 3483.8;HUVEC TERT2: 4014.7;LHCN-M2: 3874.5;TIME: 10032.6;U-138 MG: 4609.6;U-251 MG: 4256.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA050039, CAB068501" Uncertain Approved Cytosol "Secreted to blood" No No 142000000 13000000 "Cluster 22: NK-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB068501: AB_1642775, HPA050039: AB_2680997" "unprognostic (5.02e-2)" "prognostic unfavorable (5.01e-4)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.10e-2)" "unprognostic (9.04e-3)" "prognostic unfavorable (2.84e-5)" "unprognostic (6.80e-3)" "prognostic unfavorable (4.41e-6)" "unprognostic (2.33e-1)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.88e-8)" "prognostic unfavorable (3.27e-6)" "unprognostic (1.05e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (5.51e-4)" 215.5 75.3 3.1 91.6 3.4 1.7 56.2 5.2 12.8 62.1 5.0 31.7 7.4 31.1 1.0 16.4 41.3 360.3 136.0 3.9 6.6 166.2 345.8 260.2 21.3 6.4 3.7 105.6 135.1 11.8 12.3 418.0 4.5 37.8 5.4 4.9 10.6 8.0 17.8 21.2 13.1 74.3 4.8 13.8 30.3 5.5 12.7 6.7 59.5 4.3 3.5 359.9 19.2 6.0 77.3 64.4 1.2 5.1 766.6 1511.0 89.3 3483.8 654.6 1717.6 1487.4 9.4 5.5 2.7 812.6 1117.9 2367.3 18.1 0.4 269.4 1756.2 4.3 0.7 1.1 5.2 61.4 1532.6 0.2 3.8 596.1 106.9 2641.4 1374.8 928.5 4014.7 0.2 6.4 2.5 3874.5 0.4 0.6 2.2 18.2 1.3 41.7 0.6 6.1 4.8 5.1 30.3 1.0 0.8 286.3 77.2 8.3 410.9 3.3 9.9 10032.6 4609.6 204.0 1593.8 4256.0 0.6 2.9 4.2 1150.5 2.4 45.9 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 9.5 0.0 0.3 0.0 0.8 3.1 3.4 5.2 12.8 3.9 6.6 6.4 3.7 4.5 4.8 12.7 6.0 35.8 0.0 7.7 0.0 1.1 40.0 43.7 97.4 14.2 0.3 0.3 2.3 2.5 4.3 11.0 5.5 0.0 56.0 1.0 0.4 0.0 65.1 0.0 4.7 53.8 165.1 5.3 0.0 0.5 4.5 75.1 162.1 0.5 3.2 10.2 12.4 40.4 112.3 15.9 0.0 0.3 0.2 8.2 4.6 9.6 1.1 17.7 11.1 7.2 5.6 1.1 0.7 0.0 0.0 0.0 231.8 0.0 12.0 3.6 9.7 0.1 0.0 8.2 0.3 39.5 55.4 239.3 0.0 0.1 9.0 24.7 651.7 2.3 2.1 0.5 8.1 SERPINF2 "A2AP, AAP, ALPHA-2-PI, API, PLI" ENSG00000167711 "Serpin family F member 2" P08697 17 1742836-1755265 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 1578.5" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1007.7" "Cancer enriched" "Detected in all" 6 "liver cancer: 450.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 44.7" "Lineage enriched" "Detected in many" 23 "dendritic cells: 44.7" "Cell line enriched" "Detected in some" 24 "Hep G2: 145.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001885, CAB024863" Approved "Secreted to blood" NA NA 11900 61000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB024863: , HPA001885: AB_1079922" "unprognostic (2.17e-3)" "unprognostic (2.56e-3)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (3.69e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.18e-1)" "unprognostic (1.09e-3)" "unprognostic (7.05e-2)" "unprognostic (2.81e-1)" "unprognostic (7.68e-3)" "unprognostic (2.93e-1)" 11.6 2.0 1.4 4.3 1.5 0.4 18.3 1.2 2.2 7.1 11.1 4.2 0.7 8.7 101.4 3.0 19.6 0.7 2.5 2.0 1.4 74.1 1578.5 12.9 3.0 1.6 1.6 7.7 9.2 0.1 1.9 0.8 1.7 21.4 0.5 0.5 6.1 32.6 4.3 5.5 11.6 1.8 1.3 7.1 3.7 12.5 1.8 2.6 7.9 0.4 3.5 7.3 5.8 2.2 1.8 6.1 0.0 0.0 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 3.8 0.3 0.9 0.0 0.3 0.9 0.0 3.3 0.0 0.0 0.0 0.1 0.9 145.9 1.1 0.8 0.1 1.6 1.2 0.0 0.7 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.7 0.1 0.3 0.3 0.1 0.9 1.3 0.0 0.3 0.0 0.2 0.6 0.0 1.1 0.0 0.2 0.1 0.3 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.9 1.4 0.0 0.8 0.0 0.5 0.0 0.0 10.7 0.5 0.0 0.0 0.0 1.2 0.0 44.7 0.0 1.2 1.4 1.5 1.2 2.2 2.0 1.4 1.6 1.6 1.7 1.3 1.8 2.2 1.6 3.2 19.6 0.3 5.3 1.5 4.9 10.3 8.0 0.2 20.5 8.8 0.7 27.1 7.0 1.8 6.2 0.2 32.1 0.7 9.8 0.0 0.6 0.1 2.7 3.4 4.2 23.6 1.6 4.9 0.3 2.7 0.0 0.3 1.3 0.3 14.6 1007.7 7.7 0.0 1.9 2.1 12.2 32.2 20.1 0.8 33.8 8.2 1.8 1.0 10.9 0.1 0.0 1.0 0.7 3.8 2.7 26.7 3.2 2.8 2.2 87.5 4.4 0.4 0.0 1.3 1.2 0.4 0.5 1.3 1.6 0.3 2.6 0.0 3.3 1.8 SF3B1 "Hsh155, Prp10, PRPF10, SAP155, SF3b155" ENSG00000115524 "Splicing factor 3b subunit 1" O75533 2 197388515-197435079 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050275 Approved Enhanced "Nuclear speckles" NA NA 94000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA050275: AB_2681071" "unprognostic (6.86e-2)" "unprognostic (2.78e-1)" "unprognostic (2.14e-1)" "unprognostic (3.51e-1)" "unprognostic (4.42e-2)" "unprognostic (1.25e-3)" "unprognostic (2.44e-3)" "unprognostic (3.31e-3)" "unprognostic (1.25e-2)" "unprognostic (2.20e-1)" "unprognostic (6.79e-2)" "unprognostic (1.78e-2)" "unprognostic (2.57e-2)" "unprognostic (9.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" 183.8 173.9 101.7 132.7 112.4 304.8 180.7 120.5 126.1 222.8 136.8 170.9 110.4 195.8 200.0 136.8 183.8 123.2 135.7 98.2 100.8 135.4 168.5 162.8 203.0 105.7 101.9 226.5 200.7 154.9 147.8 165.3 111.0 163.2 147.3 138.4 180.4 133.2 172.4 156.5 231.6 116.5 107.5 287.8 169.2 91.4 104.9 221.9 167.8 144.8 199.3 154.4 167.1 135.8 134.9 105.4 288.6 155.9 222.8 219.2 237.8 172.6 196.7 163.2 205.9 233.0 147.2 247.5 116.6 193.1 165.8 133.7 273.4 151.2 271.8 196.5 154.8 237.5 257.4 294.3 155.4 270.1 198.6 232.1 163.0 175.9 209.3 278.6 205.9 171.0 210.2 174.0 192.3 134.2 251.1 285.6 231.4 167.5 163.8 234.4 197.9 182.9 245.8 286.4 154.2 186.7 174.7 118.2 139.2 345.1 115.2 242.5 186.8 126.9 109.4 123.3 145.8 168.7 238.8 342.0 123.7 174.8 146.5 49.8 50.4 57.5 54.5 51.7 55.4 46.1 46.2 50.9 60.5 44.1 48.7 49.2 60.8 56.7 52.5 37.5 71.3 56.2 101.7 112.4 120.5 126.1 98.2 100.8 105.7 101.9 111.0 107.5 104.9 135.8 175.6 179.5 222.9 92.4 187.4 119.0 172.0 127.1 125.7 103.4 96.4 83.3 129.2 72.9 194.0 92.0 73.0 116.8 224.1 90.1 56.7 104.8 9.2 123.9 191.0 143.1 110.5 109.0 55.5 94.8 102.3 151.6 132.0 179.0 246.9 171.1 107.1 74.4 100.6 94.2 59.7 108.1 89.5 124.7 144.1 20.6 120.2 166.1 76.5 75.9 163.9 111.1 116.4 87.0 121.1 112.0 68.3 104.6 195.6 103.8 84.2 70.5 221.5 98.5 118.3 159.5 227.9 104.6 100.5 94.3 118.8 142.7 216.2 119.4 91.4 156.1 SLC11A2 "DCT1, DMT1, NRAMP2" ENSG00000110911 "Solute carrier family 11 member 2" P49281 12 50979401-51028566 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032139, HPA032140" Uncertain Supported Mitochondria No No "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA032139: AB_10964213, HPA032140: AB_10962932" "unprognostic (4.40e-3)" "unprognostic (1.41e-2)" "unprognostic (1.50e-1)" "unprognostic (2.07e-3)" "unprognostic (2.35e-1)" "unprognostic (1.92e-1)" "unprognostic (2.09e-1)" "prognostic favorable (3.07e-6)" "unprognostic (1.06e-2)" "unprognostic (1.99e-2)" "unprognostic (1.15e-1)" "unprognostic (7.28e-2)" "unprognostic (2.29e-1)" "unprognostic (3.20e-2)" "unprognostic (2.61e-1)" "unprognostic (2.32e-2)" "unprognostic (2.24e-1)" 12.1 17.0 12.8 14.0 21.6 15.9 30.3 19.6 18.1 29.3 12.7 16.4 53.8 15.7 17.6 23.9 21.4 17.7 14.7 13.2 16.5 22.5 25.6 23.2 10.3 22.8 18.3 12.8 22.6 42.5 10.9 23.7 22.9 24.4 16.2 23.1 31.2 19.3 18.4 20.3 13.8 15.3 19.1 8.7 17.8 13.3 18.5 19.2 41.6 20.3 17.2 20.4 13.9 31.1 19.0 22.4 31.4 28.7 33.5 28.6 106.3 19.7 73.9 19.0 21.8 30.6 35.3 11.8 38.8 22.8 35.7 25.3 26.6 19.2 21.9 17.1 17.4 27.4 29.2 35.5 35.7 19.0 54.5 31.6 24.3 32.7 35.1 45.6 22.8 23.6 24.4 5.6 22.4 21.7 21.8 12.9 46.6 19.8 15.5 14.7 28.6 21.1 23.4 27.7 21.6 19.0 16.3 47.1 20.9 36.2 50.8 12.6 26.8 19.2 15.8 21.5 10.9 14.1 20.4 4.7 54.1 10.2 8.3 0.6 4.7 1.9 4.2 6.8 3.7 2.6 3.3 4.3 7.0 3.3 4.6 4.3 2.3 6.0 4.8 2.9 2.9 3.4 12.8 21.6 19.6 18.1 13.2 16.5 22.8 18.3 22.9 19.1 18.5 31.1 9.8 38.5 46.1 32.7 6.9 15.4 24.8 84.0 22.2 26.6 37.6 18.5 15.5 25.8 69.4 57.0 18.8 27.0 11.9 14.0 3.9 30.6 1.5 31.7 11.6 13.1 16.4 64.8 33.6 28.3 22.5 17.3 15.3 43.6 71.4 20.1 11.4 41.3 35.2 28.6 38.1 14.3 42.7 16.9 25.4 1.7 9.6 30.1 26.6 26.2 15.7 26.5 6.2 51.8 94.5 20.6 15.0 8.6 8.2 47.8 13.2 9.0 109.6 17.8 6.6 14.2 13.2 9.0 12.2 14.3 13.4 19.4 10.7 10.4 15.0 23.1 SLC19A2 "THTR1, TRMA" ENSG00000117479 "Solute carrier family 19 member 2" O60779 1 169463909-169485944 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 124.1;tongue: 84.9" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 84.5;Syncytiotrophoblasts: 156.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006119, HPA016599" Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA006119: AB_1079996, HPA016599: AB_1857005" "prognostic favorable (8.41e-4)" "unprognostic (8.82e-2)" "unprognostic (1.90e-1)" "unprognostic (3.29e-3)" "prognostic favorable (2.90e-4)" "unprognostic (4.45e-2)" "unprognostic (9.69e-2)" "unprognostic (1.45e-1)" "unprognostic (2.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (3.60e-2)" "unprognostic (2.14e-2)" 42.2 17.8 3.0 8.3 3.1 8.7 20.9 5.1 4.2 10.5 9.3 11.8 3.5 8.6 6.1 11.3 21.3 25.8 31.2 4.0 3.6 13.0 37.1 19.5 2.6 4.9 3.7 20.5 22.2 24.8 19.0 18.1 4.0 10.5 4.3 7.5 12.5 3.8 124.1 16.5 11.4 6.1 3.7 2.8 19.2 7.8 4.2 4.1 15.7 84.9 2.8 18.1 12.9 3.5 7.4 5.1 11.4 9.0 34.4 12.7 25.0 5.8 4.3 4.6 6.5 20.9 7.6 6.5 6.4 3.9 8.5 7.7 13.9 8.5 5.1 18.8 13.0 6.2 16.7 19.3 18.7 15.8 5.9 15.0 12.2 7.4 18.8 6.4 7.0 11.3 25.3 4.1 7.9 5.0 8.2 7.1 25.8 14.1 7.7 0.0 24.6 7.5 12.2 15.5 9.9 13.3 8.0 13.6 29.2 12.8 8.5 10.1 5.8 5.5 7.7 6.9 11.4 5.6 5.6 2.1 8.1 6.0 7.4 0.0 0.6 1.1 0.3 0.2 1.1 0.4 0.4 0.7 0.7 0.4 1.0 1.0 0.4 0.9 2.0 0.2 0.3 0.2 3.0 3.1 5.1 4.2 4.0 3.6 4.9 3.7 4.0 3.7 4.2 3.5 13.6 9.6 19.3 11.8 7.3 29.6 16.5 4.4 43.9 5.3 34.1 13.6 27.7 7.2 11.4 5.5 2.1 26.9 11.3 10.6 0.0 7.4 4.3 22.6 9.7 3.7 9.0 5.2 15.6 5.3 4.5 52.7 49.5 42.7 10.2 4.1 1.1 29.8 7.0 6.7 22.8 6.4 12.2 2.9 8.8 2.7 6.8 18.3 21.4 7.5 1.0 2.5 2.1 16.1 3.3 9.6 5.4 4.9 14.0 16.5 5.6 2.0 12.7 5.1 0.0 84.5 14.2 6.7 4.1 35.2 50.4 156.4 7.5 3.1 6.7 28.9 SLC25A38 FLJ20551 ENSG00000144659 "Solute carrier family 25 member 38" Q96DW6 3 39383370-39397351 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 73.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041027 Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA041027: AB_10794403" "unprognostic (3.82e-2)" "unprognostic (3.27e-2)" "unprognostic (1.96e-1)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.58e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-2)" "unprognostic (3.94e-2)" "unprognostic (1.94e-1)" "unprognostic (1.26e-2)" "unprognostic (5.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.06e-1)" "prognostic favorable (7.29e-4)" 19.1 35.4 22.2 18.8 23.3 70.0 21.0 25.9 26.8 23.8 33.6 28.1 25.3 27.3 27.6 14.5 27.3 19.4 20.7 22.9 26.3 28.7 58.0 21.0 36.2 24.2 24.1 44.1 45.6 38.7 30.7 15.4 25.3 29.2 36.9 23.0 22.5 23.9 48.2 16.7 25.2 20.3 22.6 27.2 33.8 18.7 26.0 33.6 52.0 35.7 35.4 27.8 19.1 23.3 24.3 38.3 24.3 41.2 56.4 46.4 30.8 33.6 46.1 48.3 43.7 26.3 5.6 67.8 19.6 31.6 40.7 18.4 55.2 40.1 36.0 43.6 45.0 52.0 33.5 40.2 75.6 37.7 33.9 58.8 46.1 46.2 93.2 44.6 31.5 52.8 47.7 40.6 36.4 35.2 44.7 67.0 66.2 35.9 44.3 16.2 26.4 47.7 37.5 45.4 24.3 31.1 11.9 65.9 34.0 44.5 33.5 35.0 26.9 38.3 26.4 56.2 48.9 54.7 93.1 41.9 29.3 48.3 24.7 30.7 9.6 18.1 38.8 5.7 44.7 50.8 39.1 43.3 14.9 37.8 41.7 40.5 1.0 57.0 8.4 18.5 55.3 29.2 22.2 23.3 25.9 26.8 22.9 26.3 24.2 24.1 25.3 22.6 26.0 23.3 10.4 22.4 27.4 8.5 35.6 11.5 13.0 12.5 28.5 13.2 26.1 22.6 16.8 22.8 9.6 27.6 6.2 35.2 33.1 21.9 21.5 15.7 6.5 26.6 16.3 11.1 12.6 73.7 8.9 16.9 32.6 13.7 16.8 38.5 22.2 24.0 9.7 27.0 15.2 5.0 10.1 25.6 12.2 7.0 13.7 12.9 15.5 9.8 12.4 1.9 11.2 18.9 29.9 7.1 6.2 13.4 22.2 13.5 23.3 17.7 23.1 31.3 12.3 12.6 6.6 15.2 14.9 11.0 7.8 19.4 10.2 19.4 36.6 32.8 26.7 8.4 SLC2A1 "CSE, DYT18, DYT9, GLUT, GLUT1, HTLVR" ENSG00000117394 "Solute carrier family 2 member 1" P11166 1 42925353-42958893 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Cancer-related genes, Cataract, Disease variant, Dystonia, Epilepsy, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 98.7;skin 1: 79.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 833.8;Erythroid cells: 520.4;Extravillous trophoblasts: 536.4;Syncytiotrophoblasts: 2482.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 241.0;CACO-2: 219.9;Hep G2: 157.4" "Low region specificity" "Detected in all" "CAB002759, HPA031345, HPA058494" Enhanced Supported Enhanced "Plasma membrane" No No 2000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "CAB002759: , HPA031345: AB_2673835, HPA058494: AB_2683734" "unprognostic (3.60e-2)" "unprognostic (5.85e-3)" "unprognostic (7.59e-2)" "unprognostic (1.31e-2)" "unprognostic (4.10e-3)" "unprognostic (3.22e-2)" "prognostic unfavorable (3.65e-8)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.10e-1)" "unprognostic (4.84e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (1.87e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (1.11e-1)" "unprognostic (9.49e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (4.05e-4)" 6.9 3.6 24.1 2.5 26.1 41.6 7.8 33.7 27.7 28.6 43.6 6.1 0.4 5.1 1.4 54.1 8.2 1.7 10.0 20.6 28.5 14.2 1.7 3.3 1.0 31.9 29.3 5.5 2.1 4.5 4.8 98.7 34.5 6.0 1.0 24.6 17.6 5.1 2.0 79.8 4.6 0.4 24.7 7.5 8.4 2.1 41.2 1.0 3.0 1.5 2.1 19.3 54.2 29.4 60.5 52.9 66.3 6.2 3.5 1.2 241.0 47.8 36.9 15.5 27.8 219.9 96.3 22.2 138.9 6.0 26.5 43.6 12.5 52.3 14.8 16.4 10.3 29.8 20.9 157.4 12.9 16.8 8.1 3.3 21.3 18.3 20.5 96.7 2.9 12.8 81.2 1.5 11.7 46.6 7.4 11.7 35.1 22.1 17.9 8.4 20.6 23.3 21.7 17.9 27.0 23.8 47.7 95.6 11.0 70.0 3.8 16.9 14.9 25.6 28.6 6.1 83.8 5.3 6.5 11.5 57.1 8.2 25.5 0.5 0.1 1.2 10.6 0.3 8.5 10.9 5.1 6.7 3.7 8.3 3.8 4.8 0.2 4.3 0.1 18.4 6.2 4.0 24.1 26.1 33.7 27.7 20.6 28.5 31.9 29.3 34.5 24.7 41.2 29.4 3.1 0.0 1.8 12.7 25.4 286.1 48.8 286.3 66.0 15.8 41.4 21.8 26.7 20.0 159.3 27.6 66.7 833.8 33.5 53.1 5.9 53.2 4.0 112.1 46.0 100.5 18.4 520.4 2.8 11.7 536.4 25.9 11.7 118.9 6.3 6.8 2.2 2.1 84.8 5.0 3.2 22.4 65.1 1.6 34.2 0.3 7.8 5.0 21.4 71.2 36.0 350.1 18.6 8.0 9.9 120.3 51.9 14.7 11.6 31.2 1.9 2.2 118.1 32.1 0.0 9.8 32.1 0.1 2.4 99.1 238.3 2482.5 20.8 5.5 11.8 105.8 SLC30A10 "DKFZp547M236, ZnT-10, ZNT8, ZRC1" ENSG00000196660 "Solute carrier family 30 member 10" Q6XR72 1 219685427-219958647 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 23.9;liver: 33.5" "Cell type enhanced" "Detected in some" "Astrocytes: 20.2;Distal enterocytes: 44.3;Early spermatids: 38.3;Hepatocytes: 21.1;Late spermatids: 36.1;Paneth cells: 14.4;Proximal enterocytes: 13.6" "Cancer enriched" "Detected in some" 14 "liver cancer: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.0;HEL: 1.5;K-562: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064547 Enhanced NA NA "Cluster 42: Non-specific - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA064547: AB_2732715" "unprognostic (7.88e-2)" "unprognostic (1.07e-2)" "unprognostic (1.02e-1)" "unprognostic (7.25e-2)" "unprognostic (1.75e-2)" "unprognostic (3.74e-3)" "unprognostic (6.96e-2)" "unprognostic (3.72e-2)" "unprognostic (1.41e-1)" "unprognostic (1.95e-2)" "unprognostic (5.10e-2)" "unprognostic (3.10e-3)" "unprognostic (4.47e-7)" "unprognostic (3.16e-1)" "unprognostic (6.11e-2)" "unprognostic (6.19e-3)" "unprognostic (5.72e-2)" 0.0 0.0 6.0 0.0 6.1 0.3 0.0 4.4 7.6 0.0 7.4 3.8 23.9 0.0 0.0 0.0 0.0 0.4 0.0 5.9 5.7 0.0 33.5 0.0 0.0 5.4 5.9 0.2 0.0 0.0 0.0 0.0 5.6 0.1 5.0 0.4 0.0 0.0 0.7 0.1 8.9 0.0 4.5 0.0 0.0 0.7 6.5 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.2 0.2 0.2 0.3 0.3 0.3 0.2 0.1 0.1 6.0 6.1 4.4 7.6 5.9 5.7 5.4 5.9 5.6 4.5 6.5 4.7 0.0 0.0 0.0 20.2 0.2 0.3 0.0 0.2 0.0 0.3 0.2 0.0 1.2 1.5 0.1 0.0 0.0 0.1 0.0 44.3 0.0 0.2 38.3 0.0 0.0 1.0 0.0 2.7 4.3 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.4 21.1 0.1 0.0 4.3 0.6 0.0 0.6 0.3 36.1 1.2 0.0 1.8 9.4 0.0 3.1 0.0 3.0 3.3 0.0 14.4 1.5 0.0 0.0 13.6 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.9 0.0 0.1 0.3 0.0 1.3 0.8 0.0 SLC39A14 "KIAA0062, NET34, ZIP14" ENSG00000104635 "Solute carrier family 39 member 14" Q15043 8 22367278-22434129 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 551.3;pancreas: 252.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 266.7;Hepatocytes: 611.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ hTERT+: 321.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016508, HPA056732" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA 1100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Golgi apparatus, Plasma membrane" "HPA016508: AB_1857148, HPA056732: " "unprognostic (1.67e-1)" "unprognostic (6.67e-3)" "prognostic favorable (5.00e-5)" "unprognostic (9.83e-3)" "unprognostic (9.21e-3)" "unprognostic (8.99e-3)" "unprognostic (1.99e-1)" "unprognostic (2.91e-2)" "unprognostic (4.95e-2)" "unprognostic (5.66e-2)" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.79e-7)" "unprognostic (4.88e-2)" "unprognostic (8.73e-2)" "unprognostic (1.63e-2)" "unprognostic (1.11e-3)" 63.5 72.4 13.0 35.5 11.0 1.4 39.8 11.9 13.1 17.3 39.7 48.2 142.2 30.2 6.2 11.6 25.9 32.0 76.7 14.5 22.9 30.8 551.3 23.9 7.6 43.0 30.4 27.7 252.7 12.9 21.5 19.0 25.7 22.3 50.3 18.6 21.8 18.7 43.0 20.0 84.9 33.0 13.3 8.1 80.5 26.5 25.3 6.0 87.7 17.4 6.9 56.0 14.5 14.8 51.8 68.3 18.4 37.6 65.1 54.7 40.1 72.8 321.0 111.3 173.5 226.9 47.9 51.1 39.9 86.1 288.9 55.6 92.8 91.1 181.9 53.1 49.2 40.8 51.0 230.7 154.3 28.5 43.2 58.4 72.6 198.0 136.9 56.3 50.5 36.5 36.2 51.2 57.3 24.0 43.4 18.2 113.4 81.9 49.8 60.1 34.9 110.8 40.8 22.3 31.3 48.7 74.3 31.3 151.4 39.7 25.1 39.4 28.0 137.3 69.2 87.4 75.7 29.2 28.7 66.9 194.3 37.7 81.9 0.0 0.4 2.1 6.7 0.1 7.2 4.0 3.8 5.0 1.5 1.9 4.3 5.9 0.1 2.7 0.1 0.7 3.4 3.4 13.0 11.0 11.9 13.1 14.5 22.9 43.0 30.4 25.7 13.3 25.3 14.8 12.4 3.2 7.7 11.4 9.1 33.3 11.5 10.8 18.8 7.8 20.3 16.6 66.6 41.5 3.8 7.3 2.1 0.4 3.6 91.6 1.9 47.6 0.5 136.1 58.3 32.2 33.4 10.5 26.2 74.7 2.7 58.8 47.9 266.7 0.0 20.8 29.6 611.4 1.8 48.8 24.6 60.6 6.1 15.4 25.8 3.2 23.9 2.9 44.4 6.5 2.7 5.2 2.1 9.0 3.9 47.3 39.1 41.8 13.5 26.5 75.6 24.6 1.1 8.2 0.0 47.1 32.2 0.7 3.0 4.1 21.0 0.5 7.4 14.7 43.5 9.4 SLC46A1 "HCP1, MGC9564, PCFT" ENSG00000076351 "Solute carrier family 46 member 1" Q96NT5 17 28394642-28407197 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 93.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.6;Hepatocytes: 27.8;Hofbauer cells: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "CACO-2: 205.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011614 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "CAB011614: AB_2270597" "unprognostic (1.10e-1)" "unprognostic (8.62e-2)" "unprognostic (1.40e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (9.11e-2)" "unprognostic (4.05e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (3.80e-2)" "unprognostic (1.04e-3)" "unprognostic (6.15e-2)" "unprognostic (2.10e-3)" "unprognostic (2.16e-1)" "unprognostic (2.94e-1)" "unprognostic (2.15e-1)" "unprognostic (1.04e-1)" 6.7 24.8 8.1 5.7 10.6 3.4 5.7 14.7 9.2 5.6 26.7 5.7 93.9 4.6 8.5 2.4 13.4 4.6 4.6 8.0 8.4 7.5 27.3 6.9 5.5 11.2 9.7 8.7 11.2 15.0 15.5 8.2 10.4 7.4 5.6 8.7 12.5 9.0 3.6 2.3 40.5 5.5 9.8 11.1 5.5 3.1 10.0 23.4 6.4 2.8 2.1 5.0 2.6 12.1 5.4 22.5 7.4 12.2 5.9 1.3 22.9 6.3 4.6 5.1 5.7 205.4 6.4 0.4 3.6 3.4 14.8 17.3 8.4 14.1 4.3 13.1 19.6 0.2 14.0 17.6 2.1 0.1 10.1 2.8 25.3 5.3 15.8 7.1 0.4 1.8 8.9 1.2 0.9 7.2 0.1 0.6 4.4 5.2 2.9 0.3 6.0 2.7 4.0 11.8 19.4 10.2 43.6 20.1 2.4 10.1 15.6 3.4 0.6 0.8 8.6 1.2 6.6 9.0 11.1 0.3 1.2 1.3 4.7 5.2 0.9 0.6 0.4 3.0 0.7 1.6 0.4 0.3 1.4 0.8 0.5 0.8 1.0 1.6 2.6 0.5 0.9 0.5 8.1 10.6 14.7 9.2 8.0 8.4 11.2 9.7 10.4 9.8 10.0 12.1 1.2 12.8 5.3 7.5 1.0 0.4 1.9 2.8 4.0 26.6 5.1 6.1 2.3 17.2 2.2 7.3 4.2 20.8 0.2 3.7 0.0 3.5 3.6 18.2 1.8 1.9 1.2 0.4 2.8 4.6 9.7 3.6 3.1 1.5 1.3 4.2 1.8 27.8 25.7 20.2 4.6 2.4 0.0 21.5 1.0 19.5 4.1 8.0 0.0 5.6 2.0 2.2 0.0 8.0 6.9 3.8 3.6 3.4 3.0 2.6 3.9 4.6 4.3 6.0 6.6 3.7 1.4 0.3 0.3 1.2 0.3 4.4 0.6 5.8 1.3 1.6 SLC4A1 "AE1, CD233, DI, EPB3, FR, RTA1A, SW, WD, WR" ENSG00000004939 "Solute carrier family 4 member 1 (Diego blood group)" P02730 17 44248390-44268141 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Blood group antigen" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "bone marrow: 407.2" "Cell type enriched" "Detected in some" 80 "Erythroid cells: 1629.2" "Cancer enriched" "Detected in single" 91 "renal cancer: 16.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 3.0;neutrophil: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "K-562: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015584, CAB034438, HPA063911" Enhanced NA NA 22000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "CAB034438: AB_2123479, HPA015584: AB_1844824, HPA063911: AB_2685151" "unprognostic (1.36e-1)" "unprognostic (1.42e-1)" "unprognostic (3.36e-1)" "unprognostic (2.44e-2)" "unprognostic (2.32e-2)" "unprognostic (1.56e-2)" "unprognostic (1.55e-1)" "unprognostic (1.59e-1)" "unprognostic (1.68e-1)" "unprognostic (1.58e-1)" "unprognostic (6.72e-3)" "unprognostic (1.19e-1)" "unprognostic (9.28e-3)" "unprognostic (1.93e-2)" "unprognostic (2.18e-1)" "unprognostic (1.94e-1)" "unprognostic (2.13e-1)" 0.5 0.3 0.7 0.3 0.7 407.2 0.2 2.2 1.4 0.1 1.7 0.2 0.3 0.1 0.3 0.3 0.1 0.3 0.9 0.6 0.5 72.1 2.2 1.8 0.4 0.8 0.6 0.1 0.2 0.0 0.6 10.9 0.9 0.1 0.1 0.7 0.4 0.1 2.2 0.5 0.2 0.0 0.3 12.8 0.3 0.3 1.1 0.7 0.3 1.5 0.1 0.1 0.1 1.7 0.2 0.0 0.3 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.2 0.4 0.4 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.1 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.8 0.2 0.2 0.1 0.6 0.0 0.3 0.1 0.1 0.4 0.2 0.3 0.3 0.1 0.1 0.6 0.6 0.1 0.3 0.3 0.2 0.2 0.1 0.2 0.1 0.4 0.5 0.2 3.0 0.3 0.5 0.2 0.3 0.2 0.3 0.2 0.2 0.1 0.5 0.2 0.2 2.7 1.1 0.4 0.3 0.1 0.2 0.7 0.7 2.2 1.4 0.6 0.5 0.8 0.6 0.9 0.3 1.1 1.7 0.8 6.4 0.6 0.3 2.0 0.0 1.3 0.0 0.0 0.4 1.0 1.1 0.7 0.0 0.6 20.2 0.0 0.4 0.1 0.2 3.9 0.1 0.8 0.2 0.4 0.7 0.0 1629.2 0.2 0.0 1.6 0.5 0.0 0.5 0.0 0.1 0.7 0.9 1.4 0.0 0.2 0.1 0.0 1.0 0.0 0.0 0.0 1.9 0.0 1.0 0.6 0.2 2.1 0.0 0.0 0.0 0.0 0.4 0.3 0.9 0.2 0.4 0.0 0.2 0.0 1.2 0.2 0.7 0.5 0.0 0.0 0.8 1.5 0.7 0.1 0.6 SLC6A2 "NAT1, NET, NET1, SLC6A5" ENSG00000103546 "Solute carrier family 6 member 2" P23975 16 55655604-55706192 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 149.4" "Group enriched" "Detected in some" 4 "Early spermatids: 4.3;Extravillous trophoblasts: 10.6;Late spermatids: 4.4;Spermatocytes: 11.5;Syncytiotrophoblasts: 5.6" "Cancer enhanced" "Detected in some" "liver cancer: 1.9" "Region enriched" "Detected in some" 10 "pons: 149.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 29 "SH-SY5Y: 489.1" "Region enriched" "Detected in some" 4 "pons and medulla: 7.8" "Region enriched" "Detected in single" 19 "pons: 13.8" "HPA004057, HPA076311, CAB078195" Enhanced Supported Approved Mitochondria,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol Mitochondria "CAB078195: AB_2665806, HPA004057: AB_1080012, HPA076311: AB_2732307" "unprognostic (9.58e-3)" "unprognostic (5.48e-2)" "unprognostic (1.26e-4)" "unprognostic (4.07e-1)" "unprognostic (4.16e-1)" "unprognostic (8.38e-2)" "unprognostic (2.97e-2)" "unprognostic (3.29e-1)" "unprognostic (2.31e-1)" "unprognostic (3.27e-1)" "unprognostic (2.12e-2)" "unprognostic (2.95e-2)" "unprognostic (1.72e-1)" "unprognostic (6.02e-2)" "unprognostic (8.48e-2)" "unprognostic (1.43e-2)" 0.9 21.7 0.1 0.0 0.1 0.0 0.8 0.0 0.2 2.4 0.0 0.2 0.1 5.4 0.2 0.2 0.5 0.1 0.0 0.1 0.0 0.4 0.4 0.1 0.0 3.8 14.6 0.1 0.0 0.5 0.0 12.6 149.4 0.2 0.3 0.0 1.9 0.6 0.0 13.3 0.2 0.8 0.1 0.0 0.1 6.2 0.0 0.1 0.0 0.0 0.1 0.2 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 5.2 3.7 489.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 3.8 14.6 149.4 0.1 0.0 0.5 1.8 0.0 0.0 0.0 0.0 1.5 0.2 0.4 0.0 0.0 0.3 0.1 0.8 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 10.6 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.5 4.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 11.5 0.3 0.0 0.4 5.6 0.0 0.0 0.0 0.1 SLFN14 ENSG00000236320 "Schlafen family member 14" P0C7P3 17 35543985-35560819 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "bone marrow: 3.9" "Group enriched" "Detected in some" 41 "Erythroid cells: 16.8;Macrophages: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HEL: 18.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA022994, HPA023065" Uncertain NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "HPA022994: AB_10670035, HPA023065: AB_2671055" "unprognostic (4.27e-3)" "unprognostic (4.72e-4)" "unprognostic (1.21e-1)" "unprognostic (6.43e-2)" "unprognostic (1.07e-3)" "unprognostic (6.50e-2)" "unprognostic (1.09e-2)" "unprognostic (3.05e-1)" "unprognostic (5.33e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-1)" "unprognostic (7.59e-8)" "unprognostic (1.21e-1)" "unprognostic (2.83e-2)" "unprognostic (1.08e-1)" "unprognostic (1.13e-3)" 0.0 0.0 0.1 0.3 0.1 3.9 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.4 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 18.7 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.8 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SLX4 "BTBD12, FANCP, KIAA1784, KIAA1987" ENSG00000188827 "SLX4 structure-specific endonuclease subunit" Q8IY92 16 3581181-3611606 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049421, HPA066238" Approved Supported "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cell Junctions, Cytosol" "HPA049421: AB_2680759, HPA066238: AB_2685642" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (4.06e-2)" "unprognostic (2.65e-2)" "unprognostic (4.62e-1)" "unprognostic (6.08e-3)" "unprognostic (8.28e-5)" "unprognostic (6.52e-2)" "unprognostic (2.49e-1)" "unprognostic (1.56e-1)" "unprognostic (1.97e-2)" "unprognostic (1.50e-1)" "unprognostic (4.32e-2)" "unprognostic (8.39e-3)" "unprognostic (1.20e-1)" "unprognostic (1.43e-3)" "unprognostic (5.74e-2)" 1.8 2.1 2.1 2.9 1.9 3.0 1.6 7.1 2.7 2.1 0.4 2.3 2.2 2.1 1.3 2.4 2.0 1.1 1.9 2.3 2.1 1.9 1.9 2.1 4.1 2.3 2.0 1.6 1.7 1.1 3.9 1.1 1.8 2.3 0.9 1.7 1.6 1.0 2.7 1.8 2.8 1.2 1.1 3.4 2.2 10.6 1.9 2.7 1.8 1.3 2.9 2.1 2.0 2.1 2.7 8.4 5.3 6.7 2.0 2.1 5.6 4.3 2.2 4.9 5.4 4.2 3.3 10.0 4.2 2.2 3.8 6.0 3.6 3.0 2.9 8.4 4.6 6.8 6.5 2.7 1.8 6.7 9.3 1.5 2.2 4.6 2.6 1.2 3.6 5.6 6.7 5.3 3.9 4.7 4.2 5.9 4.5 1.7 3.1 8.2 8.9 2.8 1.9 1.9 4.5 4.1 3.8 2.6 1.3 2.8 6.5 5.2 4.3 5.6 7.8 4.9 5.1 4.8 4.0 11.4 1.8 6.7 5.7 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 2.1 1.9 7.1 2.7 2.3 2.1 2.3 2.0 1.8 1.1 1.9 2.1 2.7 0.0 2.3 4.6 4.5 0.8 0.8 1.1 4.0 8.7 2.0 1.4 1.7 1.5 3.2 0.0 2.1 1.7 3.4 2.0 0.0 1.5 6.5 5.5 4.2 1.8 0.0 6.5 9.5 2.4 1.6 2.4 3.6 4.6 0.0 4.8 1.1 1.4 2.9 0.0 9.3 2.4 2.0 2.9 1.6 2.3 2.1 5.1 0.0 4.7 2.2 2.7 4.1 7.1 5.5 2.0 0.3 1.9 4.0 0.4 2.3 0.6 2.3 10.1 0.0 4.9 2.5 20.0 9.1 2.3 0.6 1.0 4.4 3.0 2.1 0.6 SPTA1 EL2 ENSG00000163554 "Spectrin alpha, erythrocytic 1" P02549 1 158610704-158686715 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin capping, Actin-binding" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia, Pyropoikilocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 44 "bone marrow: 75.7" "Cell type enriched" "Detected in some" 29 "Erythroid cells: 255.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "K-562: 38.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016193, HPA028048, HPA028253, CAB037246" Enhanced NA NA 11000000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "CAB016193: AB_669050, CAB037246: AB_261445, HPA028048: AB_10603341, HPA028253: AB_2672537" "unprognostic (3.39e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.99e-1)" "unprognostic (1.34e-1)" "unprognostic (3.65e-3)" "unprognostic (1.50e-3)" "unprognostic (9.08e-2)" "unprognostic (2.58e-2)" "unprognostic (2.29e-1)" "unprognostic (9.09e-2)" "unprognostic (6.73e-8)" "unprognostic (6.08e-2)" "unprognostic (6.33e-2)" "unprognostic (1.76e-2)" "unprognostic (5.85e-3)" 0.1 0.0 0.0 0.0 0.0 75.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 38.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 8.7 0.0 0.0 0.3 0.0 255.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.8 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 SPTB ENSG00000070182 "Spectrin beta, erythrocytic" P11277 14 64746283-64879907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.5;skeletal muscle: 123.9;tongue: 69.8" "Cell type enhanced" "Detected in some" "Erythroid cells: 81.0;Excitatory neurons: 16.0;Horizontal cells: 16.8;Inhibitory neurons: 32.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEL: 39.2;K-562: 47.8;U-937: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003394, HPA003398, CAB015169, CAB016232" Enhanced Approved Cytosol NA NA 7800000 "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 37: Myocytes - Muscle contraction" Cytosol "CAB015169: AB_2194363, CAB016232: AB_785785, HPA003394: AB_1080076, HPA003398: AB_1080074" "unprognostic (2.69e-1)" "unprognostic (4.72e-1)" "unprognostic (3.04e-2)" "unprognostic (2.19e-3)" "unprognostic (1.71e-1)" "unprognostic (2.33e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-3)" "unprognostic (2.66e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.39e-2)" "unprognostic (2.97e-1)" "unprognostic (3.44e-2)" "unprognostic (2.18e-2)" 2.2 1.5 5.3 0.2 11.2 62.5 0.3 28.3 11.4 0.3 27.7 0.2 0.1 0.2 5.2 2.0 0.5 0.4 22.7 10.8 4.0 1.0 0.1 0.4 0.0 28.5 5.3 0.2 2.6 11.1 5.3 6.7 28.2 1.5 0.1 1.6 2.2 1.1 123.9 0.2 0.2 0.8 8.5 0.8 0.2 0.7 9.3 0.4 0.1 69.8 0.0 0.2 0.2 4.4 0.3 1.5 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.3 2.3 6.3 0.2 0.0 0.4 3.7 39.2 0.3 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.0 1.4 47.8 0.0 0.0 0.3 0.0 0.3 0.0 0.5 2.1 0.0 0.0 0.2 0.0 0.2 6.1 2.6 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.3 6.7 0.0 0.6 1.5 7.7 0.0 0.1 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 5.3 11.2 28.3 11.4 10.8 4.0 28.5 5.3 28.2 8.5 9.3 4.4 0.1 0.0 0.0 0.7 0.0 0.8 0.7 0.6 0.0 10.3 0.5 0.1 6.3 1.5 0.7 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.4 0.4 0.9 0.4 3.0 81.0 16.0 0.2 0.3 0.8 0.0 0.9 2.5 0.2 0.0 0.0 0.2 16.8 32.1 0.3 0.0 0.0 0.4 0.4 0.3 0.3 1.8 1.9 0.0 5.0 1.0 11.1 2.1 0.3 0.0 1.2 0.1 0.7 0.0 0.2 0.0 2.6 6.6 11.6 3.8 0.1 1.1 0.5 0.4 0.1 0.6 0.4 0.1 0.6 SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 42.0;Gastric mucus-secreting cells: 43.8;Langerhans cells: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 6 "dendritic cells: 1.4;monocytes: 2.4" "Cell line enhanced" "Detected in many" "A549: 110.8;HBEC3-KT: 102.6;RT4: 106.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004023, HPA030875" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA 3200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 15: RT4 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cell Junctions" "Nucleoplasm, Cytosol" "CAB004023: AB_2106059, HPA030875: AB_2673640" "unprognostic (5.58e-2)" "unprognostic (9.83e-2)" "unprognostic (3.56e-1)" "unprognostic (4.54e-3)" "unprognostic (1.52e-1)" "unprognostic (1.54e-2)" "prognostic unfavorable (4.90e-5)" "unprognostic (3.89e-2)" "unprognostic (7.04e-2)" "unprognostic (8.13e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.63e-4)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.33e-2)" "unprognostic (4.72e-2)" "unprognostic (3.65e-2)" "prognostic favorable (5.22e-5)" 9.7 25.3 5.7 13.3 5.2 8.4 10.1 0.4 6.2 25.1 1.5 30.3 39.8 31.9 3.2 26.1 23.8 27.9 8.8 6.4 5.5 21.4 4.3 16.1 6.3 2.6 3.4 23.6 30.8 11.1 15.9 8.1 2.2 30.8 17.1 5.5 11.8 27.4 2.4 13.0 38.8 17.2 1.7 14.2 39.9 25.2 5.0 6.1 9.8 1.5 8.1 35.6 24.6 3.0 24.6 110.8 24.9 22.6 9.3 14.7 51.6 22.0 18.9 26.3 16.6 41.9 21.5 0.7 13.4 40.2 29.9 43.5 15.1 102.6 10.3 0.1 13.7 6.2 3.9 65.9 22.0 0.3 9.3 15.7 34.2 17.3 22.8 29.4 24.3 14.2 0.6 0.2 4.4 16.7 6.0 0.8 11.7 67.3 98.8 26.5 6.6 0.7 11.0 106.3 23.1 83.6 25.0 34.5 27.2 19.1 31.1 9.0 35.8 31.4 20.9 11.7 20.1 0.3 0.8 0.3 22.1 0.1 24.0 0.0 1.6 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 2.3 1.4 0.0 1.0 5.7 5.2 0.4 6.2 6.4 5.5 2.6 3.4 2.2 1.7 5.0 3.0 1.0 3.2 1.7 3.3 4.1 8.2 12.5 9.5 10.8 6.5 6.2 7.5 2.2 18.6 4.7 12.9 2.1 2.3 4.9 42.0 1.9 12.2 1.8 6.4 10.7 1.4 16.8 0.4 9.5 18.7 8.3 7.2 43.8 12.4 0.0 14.8 1.1 1.6 5.7 3.3 9.1 29.2 8.2 9.4 46.3 3.3 10.8 22.8 1.8 9.4 9.7 4.4 1.0 9.0 0.6 39.1 19.2 17.3 4.3 18.0 36.7 9.3 5.6 5.2 13.1 1.8 6.7 0.3 1.1 11.2 9.1 2.3 1.0 2.9 16.9 36.6 SRSF2 "PR264, SC-35, SC35, SFRS2, SFRS2A" ENSG00000161547 "Serine and arginine rich splicing factor 2" Q01130 17 76734115-76737333 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049905 Supported Approved Nucleoplasm,Cytosol NA NA 180000 "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA049905: AB_2680945" "unprognostic (2.50e-1)" "unprognostic (2.16e-3)" "unprognostic (2.73e-3)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.75e-2)" "unprognostic (4.19e-2)" "prognostic unfavorable (3.53e-8)" "unprognostic (1.19e-1)" "unprognostic (7.79e-3)" "unprognostic (7.03e-3)" "unprognostic (1.92e-1)" "unprognostic (1.07e-3)" "prognostic unfavorable (1.05e-7)" "unprognostic (3.85e-2)" "unprognostic (8.05e-2)" "unprognostic (1.95e-1)" "prognostic favorable (9.87e-4)" 106.0 106.8 27.8 95.5 29.6 184.7 92.1 29.9 34.0 83.6 37.7 100.3 86.2 88.9 64.0 129.5 89.5 42.1 78.5 29.2 32.9 83.0 115.2 95.4 111.6 30.8 28.5 85.6 88.3 48.4 81.9 66.0 30.3 78.0 71.6 53.4 90.6 52.3 91.7 96.5 113.2 49.0 31.3 121.6 94.4 49.5 30.0 94.2 102.1 36.0 100.2 80.0 94.3 36.0 318.7 239.8 289.5 207.5 70.9 58.5 300.5 197.3 146.8 225.4 207.0 257.2 216.8 478.0 143.3 188.7 164.3 279.9 293.3 229.0 230.2 202.3 489.3 357.9 246.6 311.9 79.3 404.4 210.6 65.2 51.1 186.2 54.0 91.1 179.9 212.0 373.4 209.6 183.7 251.0 460.0 440.9 339.5 186.4 340.2 455.0 310.6 360.5 156.5 225.2 247.7 350.8 227.1 196.3 120.4 154.0 238.8 301.6 187.9 206.9 271.3 139.4 330.0 278.2 219.2 552.9 187.3 318.9 177.1 2.5 40.9 10.0 26.0 53.3 26.0 23.5 17.7 26.7 67.0 19.6 20.1 19.4 4.4 35.6 33.6 49.2 24.0 33.0 27.8 29.6 29.9 34.0 29.2 32.9 30.8 28.5 30.3 31.3 30.0 36.0 271.3 118.6 105.6 57.5 396.7 460.8 439.7 205.9 540.1 151.9 291.7 277.9 86.2 148.7 141.5 88.3 91.8 339.4 548.0 233.1 156.5 199.1 203.6 176.8 181.9 204.3 266.3 366.6 51.1 157.3 579.7 233.9 196.7 257.4 218.4 241.7 116.7 125.1 251.3 99.3 55.4 246.9 132.2 143.7 480.4 162.0 159.1 273.5 282.8 63.7 226.9 153.3 196.7 55.8 87.9 189.0 288.7 127.5 492.0 384.8 250.5 128.7 97.4 188.9 118.3 286.8 242.1 272.3 296.8 489.5 443.4 316.0 469.1 185.4 329.4 459.4 STIM1 "D11S4896E, GOK" ENSG00000167323 "Stromal interaction molecule 1" Q13586 11 3854527-4093210 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011088, HPA012123, CAB037128, CAB037288" Enhanced Enhanced "Endoplasmic reticulum" NA NA 1900000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" "CAB037128: AB_1079007, CAB037288: AB_1079008, HPA011088: AB_1849884, HPA012123: AB_1849882" "unprognostic (2.06e-1)" "unprognostic (9.75e-2)" "unprognostic (1.34e-1)" "unprognostic (3.85e-3)" "unprognostic (3.13e-2)" "unprognostic (4.12e-1)" "unprognostic (3.43e-1)" "unprognostic (1.59e-1)" "unprognostic (2.25e-1)" "unprognostic (7.41e-2)" "unprognostic (1.86e-1)" "unprognostic (2.88e-2)" "unprognostic (9.35e-2)" "unprognostic (1.40e-1)" "unprognostic (2.73e-1)" "unprognostic (3.48e-2)" "unprognostic (1.39e-2)" 40.6 18.4 32.9 22.3 31.5 46.4 33.1 18.1 34.5 40.4 30.5 33.7 18.1 39.3 18.2 65.6 39.0 25.1 24.0 30.5 23.1 20.0 38.0 26.8 29.8 17.4 22.9 41.2 30.1 43.7 18.0 17.5 18.9 26.0 24.6 11.4 61.1 24.3 111.9 47.1 31.3 34.3 18.6 31.5 32.2 25.4 26.9 68.6 40.9 49.7 29.7 32.2 40.4 22.4 42.4 48.5 14.1 23.5 60.9 55.4 22.2 31.1 31.0 22.6 28.5 24.3 13.8 44.7 35.4 46.2 50.9 74.3 20.1 21.5 19.3 36.7 30.5 70.1 19.2 36.0 53.0 58.9 40.1 56.8 53.2 32.0 90.7 28.2 31.7 59.6 44.2 80.1 24.7 9.8 55.8 20.7 5.4 23.3 18.1 13.8 22.1 41.7 38.2 23.7 3.4 14.2 51.2 33.5 19.2 22.5 12.7 32.4 34.0 40.2 13.8 42.2 25.1 88.0 71.9 22.5 33.4 24.0 26.0 16.6 11.2 20.0 17.8 14.8 14.5 7.9 13.1 19.5 9.6 11.4 14.8 13.3 16.7 20.8 25.5 8.3 14.7 17.1 32.9 31.5 18.1 34.5 30.5 23.1 17.4 22.9 18.9 18.6 26.9 22.4 20.1 16.0 8.2 53.8 22.2 16.4 7.4 9.5 17.6 5.3 16.5 13.2 4.6 18.6 10.5 5.5 14.6 27.3 35.2 27.9 1.9 12.4 4.9 17.5 35.5 12.6 9.1 18.1 63.5 14.5 13.5 20.2 10.7 24.0 29.8 4.7 20.3 32.6 15.7 16.8 56.3 13.0 12.2 22.2 15.2 9.2 27.4 18.7 17.8 57.1 11.0 16.5 36.0 77.4 5.1 12.3 6.7 11.3 14.8 11.2 7.9 3.6 14.2 3.9 26.3 17.1 18.4 21.4 13.5 50.6 22.3 17.4 28.5 1.6 11.8 11.9 TBXA2R ENSG00000006638 "Thromboxane A2 receptor" P21731 19 3594507-3606875 "Disease related genes, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Adipocytes: 10.8;Endothelial cells: 8.7;Hepatic stellate cells: 30.7;Macrophages: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 9.5;U-2197: 6.8;U-937: 6.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA077366 Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "Nuclear speckles" "HPA077366: AB_2686836" "unprognostic (1.59e-1)" "unprognostic (3.86e-2)" "unprognostic (1.21e-2)" "unprognostic (1.74e-1)" "unprognostic (8.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.52e-2)" "unprognostic (2.17e-3)" "unprognostic (8.41e-2)" "unprognostic (6.25e-2)" "prognostic favorable (7.17e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (4.32e-2)" "unprognostic (9.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.02e-1)" 3.8 8.7 1.3 1.6 1.1 1.0 1.9 1.8 1.3 5.4 1.3 2.3 0.8 5.2 0.4 1.7 3.3 1.0 5.0 1.1 1.1 6.3 6.1 4.4 1.0 1.7 1.3 2.0 0.9 1.2 1.0 3.2 1.5 2.5 0.4 0.5 0.6 1.4 1.4 1.1 3.2 1.8 1.1 7.0 2.5 0.6 1.4 0.3 2.6 0.6 0.3 2.6 3.6 2.1 0.2 0.2 0.3 3.4 0.7 1.7 0.5 2.4 0.6 1.8 1.4 0.1 0.3 0.1 3.5 1.0 1.8 0.2 0.7 0.0 0.7 0.2 0.8 2.3 9.5 0.2 0.9 0.2 4.1 0.8 0.0 2.4 0.0 1.4 0.7 0.1 3.8 0.4 0.3 0.1 0.2 1.2 0.3 0.1 2.1 0.1 0.0 0.1 0.0 0.1 0.1 1.3 0.2 0.4 0.1 0.3 1.5 4.2 2.1 3.8 0.8 6.8 2.3 0.2 0.3 0.2 3.1 6.1 0.9 3.7 0.4 0.4 2.5 0.2 0.3 2.0 0.7 2.2 0.1 11.1 4.3 9.4 4.1 3.3 0.3 0.3 0.2 4.0 1.3 1.1 1.8 1.3 1.1 1.1 1.7 1.3 1.5 1.1 1.4 2.1 10.8 0.0 0.0 0.0 2.6 0.5 0.1 0.0 0.0 0.3 0.1 0.1 1.3 0.0 0.0 1.8 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.1 0.6 8.7 0.0 0.0 0.3 0.0 0.2 2.3 0.0 0.1 0.0 0.2 30.7 0.6 0.9 0.0 0.9 0.0 0.0 1.0 0.3 0.0 0.3 19.2 1.8 1.9 0.3 0.5 1.0 0.5 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 2.5 0.4 1.9 0.1 0.6 0.1 0.8 0.4 0.1 0.0 TERT "EST2, hEST2, TCS1, TP2, TRT" ENSG00000164362 "Telomerase reverse transcriptase" O14746 5 1253147-1295068 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase" "Cancer-related genes, Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Intestinal goblet cells: 1.0;Plasma cells: 2.8;Spermatocytes: 1.5;Spermatogonia: 4.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 438.0;fHDF/TERT166: 429.4;HBEC3-KT: 929.2;hTEC/SVTERT24-B: 560.1;LHCN-M2: 252.2;TIME: 799.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054641, HPA065897" Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "Nuclear speckles, Cytosol" "HPA054641: AB_2682554, HPA065897: AB_2685576" "unprognostic (1.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.24e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-3)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "unprognostic (6.91e-2)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (9.16e-4)" "unprognostic (8.84e-11)" "unprognostic (1.92e-1)" "unprognostic (2.15e-1)" "unprognostic (3.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 213.2 438.0 3.2 0.0 173.9 31.7 59.4 0.3 0.1 3.0 0.2 429.4 0.1 0.1 1.0 929.2 29.1 0.0 1.7 0.1 0.0 0.4 0.1 0.5 1.2 0.0 22.9 560.1 6.8 1.3 1.5 1.8 2.9 0.2 252.2 0.4 0.2 9.4 2.9 0.1 1.3 2.1 0.0 5.4 23.9 0.5 0.2 2.1 0.1 0.0 0.2 0.0 0.1 0.3 799.9 0.0 0.0 0.0 0.0 0.9 0.5 0.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 4.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 TET2 "FLJ20032, KIAA1546" ENSG00000168769 "Tet methylcytosine dioxygenase 2" Q6N021 4 105145875-105279816 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 128.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 55.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 55.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043135 Supported Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA043135: AB_10794177" "unprognostic (6.83e-2)" "unprognostic (3.52e-2)" "unprognostic (1.69e-2)" "unprognostic (9.42e-2)" "unprognostic (4.15e-2)" "unprognostic (5.88e-2)" "unprognostic (6.12e-2)" "unprognostic (1.19e-3)" "unprognostic (1.15e-2)" "unprognostic (1.57e-2)" "unprognostic (5.77e-2)" "unprognostic (7.29e-2)" "unprognostic (2.70e-3)" "unprognostic (6.10e-2)" "unprognostic (1.89e-1)" "unprognostic (9.15e-2)" "unprognostic (7.84e-2)" 4.3 3.1 2.9 10.1 4.4 22.4 5.4 2.5 2.7 6.3 5.8 5.2 6.1 7.2 6.0 7.7 4.9 5.0 3.3 2.1 4.6 4.1 4.2 5.4 5.6 5.3 4.4 4.3 3.7 4.6 1.8 10.2 5.3 4.4 5.9 6.6 4.7 3.3 2.8 11.0 6.0 5.7 2.9 7.2 5.3 1.3 4.1 5.4 4.2 5.2 7.0 5.5 4.5 5.6 5.1 3.1 10.9 11.1 2.1 3.7 4.2 3.1 4.8 4.8 4.7 3.1 6.4 0.5 4.0 4.0 2.1 4.9 9.3 6.1 5.3 6.7 2.9 7.0 6.5 1.6 4.9 15.5 11.8 3.8 7.9 4.5 5.6 8.6 6.4 4.1 7.7 13.6 4.4 3.1 2.5 4.7 2.5 6.2 2.2 8.4 4.7 1.0 4.7 9.4 7.5 5.9 4.2 9.1 0.8 5.9 4.5 11.8 9.1 7.8 6.7 2.1 5.3 9.5 6.8 6.8 4.8 3.8 7.2 30.1 13.6 14.7 3.9 10.4 1.6 5.3 2.3 2.2 10.2 6.3 1.9 2.9 55.5 5.9 13.6 8.9 3.1 3.3 2.9 4.4 2.5 2.7 2.1 4.6 5.3 4.4 5.3 2.9 4.1 5.6 24.5 25.6 29.1 58.8 28.3 14.4 11.0 14.2 12.5 22.8 15.6 13.6 27.9 5.7 23.9 9.2 16.7 23.1 34.1 19.0 7.9 7.0 0.4 22.1 38.3 20.3 23.3 10.9 48.4 7.5 5.7 18.0 21.4 33.2 27.8 15.5 13.6 8.5 14.5 35.3 89.7 15.8 32.6 48.8 93.3 0.9 8.1 98.3 5.4 90.9 48.1 5.8 34.0 112.6 128.3 8.2 18.7 7.2 22.5 12.1 16.3 2.8 22.3 24.3 13.1 47.0 21.7 0.2 1.3 28.4 35.9 34.2 18.9 24.7 14.0 27.5 TF "PRO1557, PRO2086" ENSG00000091513 Transferrin P02787 3 133746040-133796641 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Ion transport, Iron transport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "liver: 7525.8;retina: 2433.0" "Group enriched" "Detected in many" 9 "Hepatocytes: 7205.2;Muller glia cells: 12965.3" "Cancer enriched" "Detected in many" 42 "liver cancer: 783.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 48 "Hep G2: 780.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001527, HPA005692, CAB009538" Enhanced "Secreted to blood" NA NA 19800000000000 98000000000 "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "CAB009538: AB_793365, HPA001527: AB_1080357, HPA005692: AB_1080354" "prognostic favorable (4.05e-4)" "unprognostic (2.45e-2)" "unprognostic (1.78e-1)" "unprognostic (1.50e-1)" "unprognostic (8.99e-2)" "unprognostic (5.18e-2)" "unprognostic (6.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.82e-1)" "unprognostic (3.08e-1)" "unprognostic (1.37e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (2.35e-13)" "unprognostic (2.17e-3)" "unprognostic (5.49e-2)" "unprognostic (3.47e-3)" "unprognostic (9.70e-2)" 80.9 1.2 186.3 1.0 412.5 2.4 13.3 591.8 274.2 2.0 58.9 2.3 0.9 1.7 1.4 11.0 1.4 1.9 12.1 173.7 287.7 3.4 7525.8 1.9 1.3 786.9 385.4 2.1 4.6 2.2 4.4 1.3 628.2 5.4 1.2 2433.0 55.8 1.8 2.1 4.2 1.6 1.5 484.9 2.9 1.9 14.3 398.1 1.2 2.2 2.7 3.0 1.2 2.8 862.1 1.9 1.4 1.8 1.2 5.5 3.4 0.9 1.9 2.0 1.0 0.8 3.4 1.5 1.7 1.6 1.8 1.2 2.1 1.3 1.8 1.5 1.1 0.7 16.3 2.7 780.9 1.3 4.6 2.7 2.4 3.8 1.0 1.7 1.8 2.2 0.9 6.4 2.1 2.6 1.3 1.1 1.2 1.2 1.2 1.8 1.5 2.9 1.2 1.1 3.1 1.9 1.4 2.4 2.6 7.0 1.3 1.9 1.3 2.9 2.4 1.5 1.6 1.1 1.7 3.0 1.4 2.0 1.5 1.6 0.6 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.0 186.3 412.5 591.8 274.2 173.7 287.7 786.9 385.4 628.2 484.9 398.1 862.1 0.7 16.0 32.4 36.2 11.4 1.0 5.6 0.6 0.0 101.3 5.3 4.3 2.7 117.2 22.9 0.0 91.8 0.2 0.2 0.1 1.9 0.7 5.4 0.8 1.0 16.7 0.0 56.2 34.2 1.1 0.3 3.9 0.0 0.6 17.7 1.3 87.4 7205.2 0.1 47.1 34.7 0.0 0.0 124.7 0.3 3.8 0.3 4.7 0.0 9.4 0.6 12965.3 0.0 45.2 1077.2 1.1 0.0 0.4 0.0 18.7 0.0 0.5 22.1 400.4 0.0 11.6 0.4 0.5 0.4 3.6 0.0 0.3 7.8 0.5 0.0 3.0 THBD CD141 ENSG00000178726 Thrombomodulin P07204 20 23045633-23049672 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant, Hemolytic uremic syndrome, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 254.3;Endothelial cells: 200.6;Langerhans cells: 138.1;Leydig cells: 130.8;Macrophages: 130.9;Peritubular cells: 259.2;Squamous epithelial cells: 237.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 24.6" "Group enriched" "Detected in many" 7 "dendritic cells: 10.8;granulocytes: 24.6;monocytes: 9.0" "Cell line enhanced" "Detected in many" "ASC diff: 24.3;CAPAN-2: 39.2;EFO-21: 33.5;HaCaT: 33.1;hTCEpi: 42.6;OE19: 29.8;THP-1: 24.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002425, HPA002982" Supported Approved Nucleoplasm,Cytosol NA NA 5550000 1300000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "CAB002425: AB_563497, HPA002982: AB_1078444" "unprognostic (1.96e-1)" "unprognostic (2.93e-3)" "unprognostic (8.70e-2)" "unprognostic (3.00e-2)" "unprognostic (3.07e-2)" "unprognostic (1.88e-1)" "unprognostic (7.81e-3)" "unprognostic (4.70e-2)" "unprognostic (1.38e-1)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.33e-2)" "unprognostic (2.23e-2)" "unprognostic (7.35e-3)" "unprognostic (3.01e-2)" "unprognostic (7.58e-3)" "unprognostic (9.71e-2)" 65.4 11.4 2.0 19.6 1.8 15.5 25.5 1.6 3.2 16.7 3.4 16.5 5.5 12.6 3.1 36.8 27.5 26.5 31.0 2.4 3.0 19.7 9.7 56.7 14.5 4.1 2.7 6.9 13.2 9.9 20.4 28.5 2.8 8.0 5.9 0.2 10.8 4.6 40.7 71.4 20.0 15.6 3.0 43.6 30.8 7.6 8.5 5.1 35.5 17.5 8.0 20.8 21.0 2.4 11.5 9.9 0.3 0.0 24.3 1.4 0.2 0.2 0.0 0.0 0.0 0.0 39.2 0.0 33.5 3.4 1.7 33.1 0.0 1.8 0.0 0.0 0.1 0.1 1.0 0.0 4.7 0.0 0.2 1.1 42.6 0.7 2.8 23.0 11.0 0.0 4.2 0.0 0.9 0.8 0.0 4.2 0.1 29.8 1.6 0.0 0.0 4.9 0.2 16.2 0.7 0.0 9.4 1.2 17.4 2.9 0.0 24.8 21.7 0.1 0.6 3.2 0.0 0.0 0.0 0.0 2.0 5.8 0.8 0.0 4.1 0.0 0.0 9.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 24.6 2.0 8.7 10.8 0.0 2.0 2.0 1.8 1.6 3.2 2.4 3.0 4.1 2.7 2.8 3.0 8.5 2.4 254.3 22.4 21.4 0.0 2.0 34.3 10.4 9.5 23.3 0.1 3.9 5.3 16.8 1.5 21.3 0.0 0.0 3.2 16.9 0.0 0.0 1.8 0.9 1.9 1.8 200.6 0.0 2.7 0.3 0.2 37.1 46.1 2.6 7.2 7.6 0.2 65.3 0.8 14.9 0.0 0.7 0.4 4.1 32.4 138.1 4.9 130.8 130.9 16.0 1.0 8.1 0.0 0.0 0.0 0.0 9.0 0.0 259.2 2.3 4.5 0.0 0.3 2.5 0.0 6.6 51.4 39.0 0.2 1.0 237.3 98.6 42.4 3.2 2.8 0.1 58.2 TMPRSS6 "FLJ30744, MT2" ENSG00000187045 "Transmembrane serine protease 6" Q8IU80 22 37065436-37109713 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "liver: 128.4" "Group enriched" "Detected in some" 11 "Early spermatids: 61.0;Hepatocytes: 99.9;Late spermatids: 143.9" "Group enriched" "Detected in many" 14 "liver cancer: 51.3;thyroid cancer: 14.1" "Group enriched" "Detected in some" 4 "basal ganglia: 4.4;thalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Hep G2: 5.0;SCLC-21H: 8.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 3.3" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (3.93e-1)" "unprognostic (3.28e-1)" "unprognostic (8.62e-2)" "unprognostic (6.29e-5)" "unprognostic (7.95e-2)" "unprognostic (1.62e-1)" "prognostic favorable (8.16e-6)" "unprognostic (2.44e-1)" "unprognostic (3.07e-1)" "unprognostic (2.41e-1)" "unprognostic (1.16e-2)" "unprognostic (3.58e-2)" "unprognostic (1.15e-7)" "unprognostic (2.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.39e-2)" "unprognostic (3.86e-5)" 0.1 0.1 0.2 0.2 4.4 0.2 0.4 0.1 0.6 0.1 0.0 0.6 2.2 0.1 0.8 0.2 0.5 0.9 0.0 0.2 0.2 0.1 128.4 0.7 0.3 0.2 0.4 0.1 1.3 0.0 13.0 0.7 0.2 0.2 0.5 0.1 0.0 0.0 0.0 2.2 1.0 0.0 0.0 0.2 3.6 7.7 1.3 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.6 0.1 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 0.2 0.1 5.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.9 0.0 0.0 0.2 0.1 0.1 0.3 0.1 0.2 0.0 0.0 8.1 0.3 0.1 0.6 0.0 0.1 0.1 0.0 0.4 0.3 1.0 0.1 0.0 1.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.4 0.1 0.6 0.2 0.2 0.2 0.4 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.3 0.6 0.5 0.0 0.0 0.0 0.0 0.6 0.3 0.5 2.8 0.0 0.0 0.0 0.0 0.1 8.8 0.0 0.2 61.0 0.0 0.0 0.3 5.3 8.0 0.1 0.0 2.6 0.0 2.6 0.0 0.0 0.0 2.5 99.9 0.1 0.0 0.1 1.5 0.0 3.2 0.0 143.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.1 0.3 0.3 0.1 0.6 0.0 TP53 "LFS1, p53" ENSG00000141510 "Tumor protein p53" P04637 17 7661779-7687538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876, CAB079965" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 32: Non-specific - Translation" Nucleoplasm "Mitochondria, Cytosol" "CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, CAB079965: , HPA051244: AB_2681403, HPA063532: " "unprognostic (2.29e-2)" "unprognostic (8.83e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.35e-4)" "unprognostic (9.95e-2)" "unprognostic (4.00e-2)" "unprognostic (2.79e-3)" "unprognostic (4.99e-2)" "unprognostic (2.75e-2)" "unprognostic (2.55e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (1.86e-3)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (2.74e-1)" "unprognostic (1.08e-1)" 19.3 13.8 10.4 27.1 12.6 19.6 22.5 10.4 16.5 19.9 10.3 29.0 18.9 24.5 12.8 28.8 31.3 13.2 11.1 10.1 11.4 14.9 16.5 15.1 34.6 18.7 13.6 27.3 18.3 9.4 7.3 23.5 12.5 17.7 27.5 4.1 18.9 15.3 12.3 37.4 20.4 24.6 12.6 31.1 22.6 10.4 12.3 47.2 17.4 6.1 45.4 20.8 19.9 13.3 81.5 145.3 81.1 57.3 37.3 43.9 82.8 28.4 66.1 78.5 100.2 4.2 40.6 190.5 126.9 58.7 77.6 174.9 119.7 80.4 72.8 42.7 76.5 77.6 76.8 70.9 111.5 1.6 37.0 55.7 93.0 38.9 106.5 45.6 79.4 24.7 3.8 6.9 41.5 145.1 130.0 96.3 80.2 10.4 2.4 252.2 56.1 66.2 59.4 87.3 46.0 80.5 94.1 62.6 24.3 39.4 109.2 7.4 100.7 91.6 30.2 1.0 48.3 47.6 37.9 82.5 23.6 9.7 80.1 1.2 21.2 3.4 13.0 21.7 15.9 21.5 13.3 14.6 30.3 19.1 13.7 15.4 2.4 17.5 19.3 27.3 17.3 14.7 10.4 12.6 10.4 16.5 10.1 11.4 18.7 13.6 12.5 12.6 12.3 13.3 21.1 9.6 12.8 16.3 26.0 28.7 14.5 24.6 24.5 2.6 36.1 30.4 2.5 18.6 15.4 20.2 0.0 36.9 24.7 16.9 9.8 24.8 12.8 11.5 29.0 24.5 30.7 21.7 2.1 18.1 39.6 17.0 11.2 19.5 1.3 31.7 22.1 18.0 24.2 0.0 3.2 43.0 18.3 27.8 20.1 3.8 23.0 19.3 12.4 7.5 31.9 4.9 25.7 9.0 8.0 15.8 16.4 17.0 7.8 15.7 10.3 10.1 8.8 2.6 13.1 25.9 20.6 0.5 4.9 28.7 32.8 22.4 16.5 27.4 54.1 11.5 TPI1 ENSG00000111669 "Triosephosphate isomerase 1" P60174 12 6867119-6870948 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Glycolysis" "Isomerase, Lyase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2470.8;tongue: 2005.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050924, HPA053568" Uncertain Approved Nucleoplasm,Vesicles NA NA 170000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Vesicles "HPA050924: AB_2681276, HPA053568: AB_2682193" "unprognostic (2.85e-1)" "unprognostic (5.58e-3)" "unprognostic (1.65e-1)" "unprognostic (1.62e-2)" "unprognostic (6.94e-2)" "unprognostic (2.31e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (4.14e-3)" "unprognostic (7.49e-2)" "unprognostic (2.13e-2)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (6.54e-4)" "unprognostic (7.04e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" 340.4 588.6 446.2 269.7 480.2 334.8 274.5 476.5 541.9 314.1 446.9 425.6 421.0 240.5 220.2 764.4 248.2 216.8 819.8 481.0 462.0 609.0 536.1 308.6 253.9 459.2 460.4 269.9 238.1 496.4 236.8 287.2 467.2 272.1 435.3 625.0 377.6 273.3 2470.8 410.1 404.5 301.5 429.7 291.4 329.0 239.8 503.5 200.3 269.1 2005.8 410.4 363.8 440.6 454.4 1556.8 1350.5 706.1 1094.6 666.5 696.6 1236.3 1097.5 1184.9 1999.1 2407.5 1409.9 823.0 903.4 212.7 1069.7 1042.4 748.8 1671.0 1812.3 2189.4 1196.4 1265.1 1172.0 924.4 926.2 496.8 1351.5 924.0 764.0 739.7 1537.8 1305.0 2816.1 1233.3 451.0 615.0 336.5 1554.5 1130.0 709.6 1119.5 1741.0 1302.3 855.9 413.5 1156.1 930.7 1261.4 1061.1 497.2 830.0 953.3 977.8 542.7 1452.6 224.4 1003.2 778.2 1068.0 914.6 703.1 1631.7 653.4 285.7 1327.8 2153.1 821.2 784.9 1708.8 2304.1 2375.2 824.6 2402.3 845.7 863.3 820.0 808.0 2656.1 800.9 570.5 703.0 934.3 1387.7 2165.7 482.0 1106.3 4679.5 446.2 480.2 476.5 541.9 481.0 462.0 459.2 460.4 467.2 429.7 503.5 454.4 311.5 134.6 204.2 34.6 290.6 684.8 553.8 1756.4 414.9 284.6 294.3 303.3 552.5 391.7 673.0 389.9 110.5 1017.0 278.2 850.3 1508.5 1361.5 203.0 280.8 307.0 352.0 425.5 243.3 38.4 786.5 1824.0 386.5 408.3 343.9 362.8 364.8 276.6 547.3 937.3 297.8 33.7 567.2 1151.5 386.7 750.4 683.5 279.0 482.8 674.1 18.7 1129.8 739.6 312.0 17.1 26.7 1081.5 889.4 263.3 427.9 556.2 1595.9 1642.7 401.2 298.0 197.2 270.5 551.3 14.9 79.0 690.4 615.9 1530.4 352.9 869.2 827.0 652.5 TSR2 "DT1P1A10, RP1-112K5.2, WGG1" ENSG00000158526 "TSR2 ribosome maturation factor" Q969E8 X 54440404-54448032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030514 Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytosol" "HPA030514: AB_10603457" "unprognostic (1.05e-1)" "unprognostic (1.80e-2)" "unprognostic (1.77e-2)" "unprognostic (1.58e-2)" "unprognostic (2.64e-2)" "unprognostic (5.91e-2)" "unprognostic (7.15e-3)" "unprognostic (8.29e-2)" "unprognostic (4.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.94e-2)" "unprognostic (6.19e-2)" "prognostic favorable (1.21e-6)" "unprognostic (2.27e-1)" "unprognostic (1.13e-1)" "unprognostic (7.93e-3)" "unprognostic (1.80e-3)" 35.2 45.1 50.9 11.2 49.9 11.9 35.6 43.4 59.4 36.8 39.3 42.2 10.2 34.9 23.0 34.6 32.2 7.7 45.5 46.2 52.9 43.8 36.7 30.4 12.6 48.9 48.0 34.6 30.2 25.0 47.1 14.6 47.3 33.3 13.3 27.4 32.6 16.9 51.7 40.7 31.3 13.2 50.3 32.4 38.8 16.5 50.6 14.9 41.1 18.6 15.8 36.3 35.0 47.8 24.1 26.6 23.9 20.6 19.9 13.0 18.7 22.4 17.5 19.6 17.3 26.2 24.1 23.5 15.8 18.2 35.7 24.9 47.9 28.3 24.8 29.8 26.8 19.3 20.8 19.6 12.5 32.7 19.4 12.9 18.0 26.4 27.1 19.7 13.8 22.9 20.5 16.9 19.3 37.9 27.4 29.9 34.6 23.6 33.0 26.5 38.2 19.6 20.6 18.3 25.9 20.5 42.1 19.9 28.0 38.0 45.4 14.7 21.0 16.2 27.1 38.0 19.9 19.8 32.3 29.7 24.4 27.5 23.2 29.7 16.6 32.0 36.3 23.1 30.0 44.8 34.0 33.6 15.1 46.3 42.6 32.3 10.4 29.7 26.0 16.7 40.8 24.9 50.9 49.9 43.4 59.4 46.2 52.9 48.9 48.0 47.3 50.3 50.6 47.8 39.1 25.6 30.2 1.6 39.8 32.8 43.0 42.7 26.7 61.6 27.4 28.6 49.0 28.6 38.6 35.0 27.1 98.5 36.0 26.3 125.2 43.9 1.2 17.7 23.7 35.6 18.1 18.1 5.7 32.9 71.5 33.8 16.8 22.9 45.0 20.3 31.8 25.2 46.6 57.2 5.6 35.5 61.1 18.2 31.4 2.8 34.8 24.6 40.9 6.5 48.6 85.6 44.3 2.5 6.5 38.1 29.5 45.1 22.3 36.7 32.6 64.6 33.8 67.0 46.0 29.8 38.0 20.5 43.3 25.4 31.7 75.9 37.8 36.2 30.9 33.9 TUBB1 dJ543J19.4 ENSG00000101162 "Tubulin beta 1 class VI" Q9H4B7 20 59019429-59026654 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.5;lymphoid tissue: 4.3" "Cell type enriched" "Detected in some" 10 "Macrophages: 191.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 17 "basophil: 63.5;neutrophil: 26.0" "Lineage enriched" "Detected in many" 24 "granulocytes: 63.5" "Cell line enriched" "Detected in some" 19 "HEL: 29.5" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004286, HPA043640, HPA046280" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA 87000000 "Cluster 34: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB004286: AB_2288090, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (3.76e-1)" "unprognostic (2.69e-1)" "unprognostic (6.10e-4)" "unprognostic (1.02e-1)" "unprognostic (5.00e-2)" "unprognostic (2.02e-1)" "unprognostic (5.86e-2)" "unprognostic (7.51e-4)" "unprognostic (1.90e-2)" "unprognostic (2.63e-1)" "unprognostic (6.80e-5)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "unprognostic (2.55e-1)" "unprognostic (1.40e-1)" "unprognostic (2.31e-1)" "unprognostic (1.00e-1)" 0.2 0.2 0.2 0.3 0.2 8.5 0.1 0.5 0.5 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.1 0.3 2.4 0.2 0.3 0.2 0.1 0.1 0.0 0.3 1.1 0.2 0.0 0.0 0.2 0.1 0.0 0.4 0.1 0.2 0.0 0.1 4.3 0.1 0.9 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.3 0.1 0.3 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.2 0.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 29.5 0.8 1.5 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.4 0.0 0.0 0.1 0.3 0.3 0.0 0.1 0.4 0.2 0.1 0.3 0.0 0.3 0.3 0.2 0.2 0.6 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.3 0.1 0.2 0.3 0.2 0.1 0.2 0.4 63.5 2.4 1.9 0.5 0.6 0.4 0.9 0.2 0.0 1.1 0.5 0.4 0.0 26.0 0.2 0.3 2.6 0.5 281.6 0.2 0.2 0.5 0.5 0.1 0.2 0.3 0.2 0.2 0.1 0.2 0.3 0.1 0.0 1.1 0.3 1.4 0.0 0.0 0.0 0.0 1.7 0.1 0.1 0.1 0.0 0.6 0.0 4.2 0.0 3.1 0.0 0.0 0.0 16.0 0.3 0.2 1.5 0.0 19.0 0.2 0.0 0.1 0.1 0.0 0.7 1.3 0.0 3.6 0.2 0.3 0.0 0.2 0.0 0.0 2.8 0.0 5.9 0.3 191.2 0.0 0.0 13.8 0.2 13.4 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.1 1.0 0.1 0.1 0.1 U2AF1 "RN, RNU2AF1, U2AF35, U2AFBP" ENSG00000160201 "U2 small nuclear RNA auxiliary factor 1" Q01081 21 43092956-43107570 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 492.9;Basal respiratory cells: 406.9;Ionocytes: 266.5;Langerhans cells: 374.7;Suprabasal keratinocytes: 433.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 607.7" "Low region specificity" "Detected in all" "HPA044833, HPA052083" Supported Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 36: HEL - Hemostasis" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA044833: AB_10960990, HPA052083: AB_2681720" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (5.98e-2)" "unprognostic (2.87e-2)" "unprognostic (1.36e-1)" "unprognostic (8.06e-2)" "unprognostic (2.76e-2)" "unprognostic (4.29e-4)" "unprognostic (4.81e-4)" "unprognostic (3.42e-2)" "unprognostic (2.31e-3)" "unprognostic (8.85e-2)" "unprognostic (2.14e-6)" "unprognostic (1.08e-1)" "unprognostic (1.40e-2)" "unprognostic (1.72e-1)" "unprognostic (1.26e-2)" 62.9 47.6 36.8 31.1 39.9 85.9 58.7 39.8 46.9 57.6 38.0 79.3 25.8 68.9 27.8 64.3 60.8 18.7 43.0 37.7 41.1 42.8 48.0 57.3 45.2 39.3 40.2 69.3 41.8 32.7 60.1 34.6 38.5 48.0 26.8 28.9 49.1 40.8 74.9 47.5 57.2 35.8 38.3 65.4 58.2 54.4 38.8 61.8 62.6 24.8 55.9 60.7 50.7 40.8 101.1 27.7 250.5 71.3 28.7 38.8 248.1 88.2 82.4 105.4 115.3 486.0 59.8 20.8 35.1 54.3 125.6 33.0 161.1 36.3 104.9 114.6 134.0 607.7 61.2 117.9 77.0 264.0 115.2 45.5 90.6 177.1 100.6 43.5 62.8 238.0 105.8 113.4 97.2 324.4 271.1 358.1 287.6 123.4 108.3 485.1 166.9 211.9 99.8 15.4 125.9 77.6 212.6 98.6 147.6 36.5 125.5 147.5 12.1 79.2 59.6 82.0 236.3 191.4 178.3 48.8 80.3 333.6 118.6 211.9 141.0 153.1 101.2 140.4 106.7 140.2 112.7 95.5 150.4 134.2 112.9 109.1 213.1 93.1 196.9 240.7 149.3 188.7 36.8 39.9 39.8 46.9 37.7 41.1 39.3 40.2 38.5 38.3 38.8 40.8 9.5 19.2 18.1 3.9 37.8 492.9 32.5 406.9 86.6 23.9 5.7 2.8 5.0 17.2 153.5 1.8 43.8 19.5 15.3 16.5 1.9 5.2 3.1 4.2 4.4 51.7 18.2 45.0 5.2 6.0 20.7 51.8 44.4 4.2 28.4 3.8 31.8 16.2 23.2 18.5 4.6 17.0 266.5 33.0 374.7 4.1 18.3 30.6 202.7 4.7 19.3 13.0 27.8 3.0 6.2 4.8 17.0 22.6 60.3 31.1 43.2 3.1 107.6 60.7 6.6 39.1 110.7 16.4 18.9 79.8 433.6 23.8 46.6 1.3 20.2 39.1 UBE2T "FANCT, HSPC150" ENSG00000077152 "Ubiquitin conjugating enzyme E2 T" Q9NPD8 1 202331657-202341980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.5;Erythroid cells: 134.3;Extravillous trophoblasts: 103.4;Spermatocytes: 114.1;Spermatogonia: 113.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002831 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli Nucleoplasm "HPA002831: AB_1080445" "unprognostic (2.38e-3)" "unprognostic (6.37e-2)" "unprognostic (5.27e-2)" "unprognostic (5.19e-2)" "unprognostic (2.81e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.71e-2)" "unprognostic (2.32e-2)" "prognostic favorable (6.90e-6)" "unprognostic (6.28e-3)" "unprognostic (2.85e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (5.37e-3)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (4.86e-2)" 2.3 3.7 6.6 10.4 6.5 28.7 4.5 5.8 13.7 4.1 5.0 13.1 8.7 4.5 4.4 10.6 3.3 2.5 11.3 6.8 7.4 3.5 3.2 3.0 19.0 6.5 6.6 1.0 0.7 4.4 3.0 10.1 6.9 2.1 15.5 2.5 2.7 3.1 17.2 5.3 8.2 9.4 6.0 6.2 4.7 19.3 6.7 47.1 2.9 13.0 18.6 6.3 5.0 6.1 123.3 111.6 167.1 79.8 15.4 27.9 94.2 130.2 72.8 146.0 102.6 79.9 147.1 140.4 50.0 47.0 108.4 98.6 154.1 76.7 131.2 128.1 87.2 85.6 54.0 93.8 6.9 105.2 102.0 9.8 18.1 114.0 47.2 34.3 85.8 157.4 111.0 114.0 116.4 113.3 190.8 135.1 65.4 126.9 57.4 145.0 176.2 122.9 57.1 58.1 131.3 132.8 90.2 112.1 44.8 49.8 117.1 64.6 41.8 65.7 104.6 116.1 159.6 57.8 120.1 182.9 64.5 107.0 139.1 0.0 0.7 1.7 3.3 2.3 2.5 8.5 4.5 3.3 1.7 6.6 6.4 7.1 0.0 1.2 8.9 3.4 10.8 2.4 6.6 6.5 5.8 13.7 6.8 7.4 6.5 6.6 6.9 6.0 6.7 6.1 1.9 0.0 2.2 1.3 13.3 14.3 10.4 29.9 2.8 6.4 6.3 8.6 12.8 0.0 12.1 5.5 0.0 74.5 5.4 10.1 5.9 10.9 24.4 15.7 7.6 5.3 1.2 134.3 8.3 7.5 103.4 11.8 10.7 6.7 8.8 32.2 3.9 2.4 27.7 10.1 6.1 14.4 32.6 1.9 5.4 8.2 3.1 5.8 3.6 1.9 2.6 1.6 0.0 1.0 1.4 10.3 2.9 4.1 32.1 5.2 3.3 12.2 16.2 1.2 6.6 0.8 11.3 114.1 113.1 15.5 10.9 22.4 9.3 12.1 30.5 11.3 VHL VHL1 ENSG00000134086 "Von Hippel-Lindau tumor suppressor" P40337 3 10141778-10153667 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Congenital erythrocytosis, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 146.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031631, HPA031632, HPA068954" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA031631: AB_2673968, HPA031632: AB_2673969, HPA068954: " "prognostic unfavorable (9.02e-5)" "unprognostic (1.10e-1)" "unprognostic (4.46e-3)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (3.55e-1)" "unprognostic (3.03e-2)" "unprognostic (4.36e-2)" "unprognostic (5.82e-3)" "unprognostic (1.81e-2)" "unprognostic (2.51e-1)" "prognostic favorable (7.84e-4)" "unprognostic (1.46e-1)" "unprognostic (2.92e-2)" "unprognostic (1.28e-3)" 14.0 13.7 11.5 21.1 11.0 27.9 14.7 13.6 12.1 11.8 6.7 14.8 15.7 14.1 9.8 12.3 13.4 11.5 7.9 11.8 14.9 12.6 14.1 11.8 29.6 9.4 9.4 12.6 12.7 11.7 9.0 14.1 9.3 14.0 15.7 8.9 14.5 10.2 11.4 14.2 17.2 12.8 9.6 22.5 16.0 13.4 16.6 23.4 15.8 7.7 29.7 12.5 10.9 12.5 19.5 18.2 39.9 24.6 36.0 27.7 146.5 16.8 24.0 21.1 24.5 21.5 23.7 67.9 22.2 23.0 29.9 16.4 37.2 23.6 25.7 33.0 33.7 52.7 30.5 30.6 34.3 47.3 41.3 28.1 26.3 28.0 35.1 28.4 24.6 42.5 48.3 50.3 21.1 35.0 45.5 40.9 26.7 21.1 23.4 57.3 34.6 34.6 25.5 48.7 15.0 49.4 35.0 18.7 21.0 23.9 37.0 59.1 21.3 20.8 27.7 19.6 26.8 35.7 78.1 105.6 23.2 55.3 19.4 4.6 3.2 2.3 2.6 2.2 1.9 2.5 1.8 2.2 2.0 3.3 1.7 1.8 5.6 3.0 2.0 2.3 1.7 1.2 11.5 11.0 13.6 12.1 11.8 14.9 9.4 9.4 9.3 9.6 16.6 12.5 12.4 12.8 12.5 9.1 38.7 14.7 17.8 14.3 24.5 14.7 10.7 6.1 6.1 20.0 9.6 16.5 18.8 16.8 21.9 10.7 7.9 11.8 9.6 13.1 26.1 14.8 14.4 30.5 15.9 5.1 18.7 12.8 20.9 19.9 5.1 18.4 18.9 14.3 14.9 18.5 14.2 11.3 16.2 27.1 45.8 7.3 14.0 32.3 12.4 7.5 31.9 9.1 28.8 12.1 14.9 10.7 11.7 11.3 33.3 23.8 12.3 9.5 9.7 15.3 6.6 17.4 11.9 15.4 24.0 26.7 20.5 17.2 23.5 21.4 10.2 25.9 VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 454.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 749.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 638.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (5.99e-2)" "unprognostic (2.98e-1)" "unprognostic (7.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.49e-2)" "unprognostic (3.23e-3)" "unprognostic (3.02e-2)" "unprognostic (2.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.09e-10)" "unprognostic (1.11e-2)" "unprognostic (6.65e-2)" "unprognostic (3.12e-2)" "unprognostic (9.66e-2)" 99.4 107.6 56.0 38.4 60.4 55.2 87.0 60.3 73.5 111.0 64.9 97.0 44.2 109.9 87.2 51.8 90.8 58.9 99.1 57.4 59.3 122.7 454.9 77.4 35.8 64.4 59.5 115.1 168.0 51.3 115.7 45.6 63.8 76.3 41.1 23.0 92.4 69.8 34.4 81.1 82.3 84.7 59.9 62.2 88.1 55.6 68.5 35.0 76.3 32.2 32.6 100.6 88.0 64.8 73.6 187.7 57.2 165.4 638.0 389.6 68.2 269.0 229.3 128.9 218.5 79.0 83.3 54.9 141.6 331.6 87.2 66.2 79.4 103.5 139.5 81.9 204.8 52.5 239.9 378.2 103.1 104.1 74.1 225.0 54.2 173.4 146.6 336.8 141.0 78.2 70.3 130.6 253.6 271.1 74.4 205.9 106.8 98.0 175.9 132.7 160.3 286.8 127.7 61.8 119.5 146.9 118.7 84.2 137.8 91.2 138.3 123.9 126.8 171.1 61.5 159.6 101.9 76.1 80.2 50.7 445.8 174.5 90.8 77.0 127.5 196.2 118.1 94.7 116.8 91.7 116.7 119.4 127.6 102.6 102.9 101.4 104.0 84.2 98.2 157.4 143.1 112.8 56.0 60.4 60.3 73.5 57.4 59.3 64.4 59.5 63.8 59.9 68.5 64.8 95.1 57.7 51.0 5.9 30.6 84.6 68.0 157.0 10.8 12.3 93.3 117.3 20.9 141.5 64.3 108.5 8.4 85.7 48.1 34.3 62.6 204.2 6.1 25.8 83.7 89.5 67.1 32.4 8.8 129.4 293.6 132.8 10.7 48.8 55.3 60.3 118.9 749.9 184.1 10.1 7.5 44.2 46.8 80.1 94.3 13.9 158.1 66.9 115.6 5.6 107.4 68.8 51.5 6.6 17.6 103.8 28.2 172.3 29.5 59.5 152.9 204.6 33.4 19.3 59.2 78.4 99.8 30.6 34.2 10.7 112.0 39.5 39.7 82.4 49.0 55.2 VWF F8VWF ENSG00000110799 "Von Willebrand factor" P04275 12 5948877-6124770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 904.3;Endothelial cells: 737.5;Hepatic stellate cells: 424.4" "Cancer enhanced" "Detected in all" "renal cancer: 76.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "HUVEC TERT2: 560.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001694, HPA001815, HPA002082, CAB072874, CAB072875" Supported "Secreted to blood" NA NA 28300000000 5600000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB001694: , CAB072874: AB_2665726, CAB072875: AB_2665727, HPA001815: AB_611880, HPA002082: AB_1080575" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.91e-3)" "unprognostic (7.09e-2)" "unprognostic (4.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.92e-2)" "unprognostic (4.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.55e-1)" "unprognostic (3.12e-1)" "unprognostic (2.73e-3)" 151.9 5.9 40.0 20.2 38.8 0.8 117.3 32.9 31.4 46.0 29.2 32.7 12.8 51.1 10.6 21.9 45.7 30.2 137.8 27.4 32.3 9.7 2.1 106.2 22.8 37.6 37.4 22.0 15.0 27.3 6.3 72.7 41.7 27.4 9.2 2.9 18.1 19.2 57.0 23.5 34.5 44.2 32.2 44.1 25.7 10.8 52.4 7.0 50.8 51.6 9.5 39.7 35.5 37.1 0.0 0.0 0.0 0.0 0.7 0.6 0.5 0.0 0.6 0.2 0.4 0.0 0.3 0.0 1.2 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 560.9 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.3 0.5 0.4 0.0 0.1 10.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 40.0 38.8 32.9 31.4 27.4 32.3 37.6 37.4 41.7 32.2 52.4 37.1 904.3 12.8 25.7 3.6 1.0 6.6 0.6 1.3 4.6 0.0 4.5 4.7 112.2 1.5 1.7 11.0 0.0 1.1 2.6 0.0 0.0 0.5 6.8 2.0 1.6 737.5 0.0 2.7 2.9 0.0 0.9 21.1 0.0 2.1 5.7 0.1 424.4 3.3 0.5 0.0 2.2 0.0 4.1 5.3 3.4 15.5 5.9 2.6 5.4 75.9 0.3 0.7 0.0 1.5 4.2 0.0 0.0 0.7 0.0 1.3 0.0 0.1 1.0 1.7 0.0 12.4 34.7 2.9 5.7 4.7 4.3 1.0 2.0 10.6 0.0 1.7 WAS "IMD2, THC, WASP, WASPA" ENSG00000015285 "WASP actin nucleation promoting factor" P42768 X 48676596-48691427 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.4;lymphoid tissue: 83.0" "Cell type enhanced" "Detected in many" "B-cells: 83.2;dendritic cells: 91.7;Hofbauer cells: 111.5;Kupffer cells: 110.7;Macrophages: 118.1;monocytes: 88.2;NK-cells: 84.5;Plasma cells: 57.8;T-cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 37.4" "Group enriched" "Detected in all" 4 "granulocytes: 37.4;monocytes: 9.5" "Cell line enhanced" "Detected in some" "Daudi: 76.5;HEL: 67.6;HMC-1: 157.0;MOLT-4: 70.8;NB-4: 75.7;RPMI-8226: 94.0;THP-1: 68.8;U-266/70: 83.1;U-937: 87.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002022, CAB004290" Enhanced Approved "Plasma membrane,Cytosol" NA NA 600000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "CAB004290: AB_628445, HPA002022: AB_1080581" "unprognostic (1.43e-3)" "unprognostic (2.09e-3)" "unprognostic (2.36e-2)" "prognostic favorable (4.95e-4)" "unprognostic (9.89e-2)" "prognostic favorable (3.78e-4)" "unprognostic (5.12e-3)" "unprognostic (7.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (7.40e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (2.24e-1)" "unprognostic (2.37e-2)" "unprognostic (3.55e-2)" "unprognostic (1.71e-1)" 10.2 5.2 6.3 52.2 5.8 58.4 4.4 5.9 8.1 3.3 6.3 6.4 8.0 2.8 3.0 3.5 5.6 6.9 3.5 6.0 8.0 4.4 7.2 19.1 54.2 11.1 8.2 1.8 2.4 1.4 2.9 9.0 8.6 4.2 5.0 0.4 4.9 2.8 1.4 2.8 23.0 6.1 8.0 83.0 7.0 1.9 8.6 42.0 3.5 3.4 36.2 10.3 3.0 10.8 0.8 0.2 0.4 1.0 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.6 0.9 76.5 0.3 0.0 0.3 2.0 0.3 0.2 0.0 44.2 0.4 67.6 0.9 0.0 0.8 34.9 157.0 0.3 0.1 0.1 0.0 0.0 0.0 40.3 0.7 45.7 0.0 7.6 70.8 75.7 0.4 1.1 0.4 61.1 0.3 94.0 0.1 0.0 0.5 0.9 1.0 0.7 0.5 0.2 0.4 68.8 0.5 0.1 0.4 1.2 0.1 83.1 43.6 53.7 0.5 87.4 0.2 3.3 7.6 37.4 4.6 8.4 3.4 3.0 3.5 3.9 5.7 3.3 3.1 3.5 29.2 3.6 9.5 3.1 5.4 4.0 6.3 5.8 5.9 8.1 6.0 8.0 11.1 8.2 8.6 8.0 8.6 10.8 1.5 3.2 14.3 0.7 83.2 2.4 0.2 0.2 2.2 0.2 1.1 1.8 1.1 0.0 0.1 0.0 0.0 0.9 91.7 0.3 1.9 0.4 0.6 0.4 0.4 2.6 1.2 14.1 0.3 0.4 1.1 1.5 5.6 0.3 48.1 0.2 3.9 1.6 111.5 0.0 0.3 0.2 0.0 110.7 54.5 1.1 0.0 118.1 3.6 4.7 88.2 0.2 84.5 0.5 0.0 0.1 0.1 0.0 57.8 0.2 0.1 1.8 1.6 0.2 0.0 1.0 1.3 1.3 1.1 0.8 1.4 1.4 99.3 0.4 0.1 0.2 XRCC2 FANCU ENSG00000196584 "X-ray repair cross complementing 2" O43543 7 152644776-152676141 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 14.1;Extravillous trophoblasts: 21.2;Granulosa cells: 20.2;Spermatocytes: 31.3;Spermatogonia: 19.1;Syncytiotrophoblasts: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065153 Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Vesicles" "HPA065153: AB_2685422" "unprognostic (9.31e-3)" "unprognostic (8.25e-2)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (9.10e-2)" "unprognostic (2.52e-2)" "unprognostic (3.36e-5)" "unprognostic (9.98e-3)" "unprognostic (5.82e-3)" "unprognostic (4.04e-3)" "unprognostic (1.06e-3)" "unprognostic (2.43e-2)" "unprognostic (1.55e-15)" "unprognostic (4.52e-3)" "unprognostic (3.01e-1)" "unprognostic (5.14e-1)" "unprognostic (1.73e-2)" 0.2 0.2 0.9 2.3 0.6 5.3 1.5 1.6 2.8 0.3 0.0 1.1 1.7 1.1 0.9 1.0 0.5 0.4 1.0 0.6 1.9 0.4 0.4 0.5 2.9 0.6 0.6 1.0 0.0 0.6 0.0 2.1 1.4 0.7 1.7 1.9 0.2 0.4 0.1 1.9 1.5 0.5 1.1 1.0 1.0 3.0 1.0 3.6 0.6 0.0 2.5 0.5 0.1 1.9 16.5 10.4 18.3 15.8 1.1 1.8 15.0 11.8 3.9 8.2 10.3 14.7 12.8 24.8 9.5 3.5 13.7 13.7 12.8 7.1 19.3 8.9 17.3 16.8 15.5 10.0 0.3 27.3 9.3 0.9 1.1 15.6 3.6 2.0 3.8 15.5 34.2 22.8 8.3 12.6 32.4 21.2 21.6 10.8 12.9 22.8 19.3 15.3 3.1 10.3 16.7 18.1 11.7 7.6 5.0 11.3 5.4 8.3 4.2 17.2 6.9 13.3 23.0 8.8 14.5 19.0 11.0 20.9 20.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.6 1.6 2.8 0.6 1.9 0.6 0.6 1.4 1.1 1.0 1.9 0.2 0.0 1.1 1.6 1.9 1.3 1.0 1.0 0.0 4.9 0.8 0.4 2.9 0.0 1.4 1.8 0.0 11.2 0.4 0.9 0.0 1.1 11.7 0.9 1.9 1.1 0.0 14.1 2.3 0.2 21.2 2.5 3.1 1.4 0.0 20.2 1.1 0.2 2.4 0.0 2.0 1.7 2.0 0.6 0.8 4.9 0.9 0.8 0.0 0.0 0.6 1.1 3.1 4.5 2.0 0.5 0.1 1.2 6.1 0.6 0.3 0.3 0.1 2.3 0.0 1.9 1.8 31.3 19.1 2.7 1.4 12.6 2.2 1.2 2.3 1.0 ZRSR2 "U2AF1-RS2, U2AF1L2, URP, ZC3H22" ENSG00000169249 "Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2" Q15696 X 15790472-15823260 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "prognostic favorable (7.96e-4)" "unprognostic (1.54e-2)" "unprognostic (7.31e-2)" "prognostic favorable (8.50e-5)" "unprognostic (8.08e-2)" "unprognostic (1.69e-1)" "unprognostic (6.14e-3)" "unprognostic (5.72e-3)" "unprognostic (8.46e-2)" "unprognostic (3.47e-3)" "unprognostic (6.90e-2)" "unprognostic (2.85e-2)" "prognostic unfavorable (4.87e-5)" "unprognostic (8.14e-2)" "unprognostic (3.04e-1)" "unprognostic (1.65e-2)" "prognostic favorable (2.97e-4)" 15.2 12.1 25.7 17.3 25.1 42.7 16.2 28.8 36.1 24.3 26.5 22.9 11.0 21.3 20.2 13.4 20.2 10.2 17.2 24.4 27.5 16.2 13.3 20.1 29.0 25.9 24.9 22.2 14.3 13.0 24.1 10.8 24.9 18.1 12.5 22.2 13.9 11.9 20.4 15.4 19.8 17.0 23.2 31.8 14.8 5.6 26.0 21.9 17.4 13.1 20.2 18.1 20.1 26.3 14.3 8.9 15.6 14.7 21.9 18.4 6.1 11.4 10.5 10.8 11.0 11.3 11.3 16.1 19.2 10.6 28.3 13.7 15.6 19.9 11.0 12.3 20.0 10.4 22.8 10.1 14.8 24.4 23.9 9.2 17.7 20.0 32.4 21.3 18.9 15.5 17.0 15.3 12.9 17.5 13.0 25.4 20.1 7.5 12.7 15.1 22.0 16.4 12.9 11.0 10.6 11.8 26.7 23.5 17.7 21.4 18.4 13.6 13.2 10.7 7.8 28.7 11.0 12.9 11.7 15.0 8.2 17.0 14.2 38.7 25.7 24.0 17.3 22.6 17.2 34.9 21.6 23.2 15.1 37.2 26.1 18.5 26.9 14.3 22.9 24.6 24.3 10.5 25.7 25.1 28.8 36.1 24.4 27.5 25.9 24.9 24.9 23.2 26.0 26.3 16.7 9.6 17.4 12.1 35.6 11.3 10.2 16.6 12.0 15.3 13.8 12.1 23.9 5.7 17.2 16.5 14.6 6.8 42.3 14.0 23.5 12.8 1.1 27.7 14.3 14.2 16.8 9.9 15.5 14.9 10.2 11.5 4.6 14.1 32.3 9.7 11.0 13.8 19.1 8.4 17.9 16.9 22.4 33.5 19.6 1.6 13.7 25.6 12.4 14.0 30.5 9.6 37.0 10.1 13.7 13.1 8.2 16.6 18.8 7.0 17.3 17.7 23.7 19.5 19.7 13.8 16.2 6.4 8.3 7.8 10.5 7.3 32.2 9.3 13.4 8.0