Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ALOXE3 "E-LOX, eLOX3" ENSG00000179148 "Arachidonate lipoxygenase 3" Q9BYJ1 17 8095900-8119047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "skin 1: 56.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.1;Pancreatic endocrine cells: 6.3;Prostatic glandular cells: 1.8;Spermatocytes: 1.8;Spermatogonia: 1.7;Suprabasal keratinocytes: 1.8" "Group enriched" "Detected in some" 4 "cervical cancer: 1.1;head and neck cancer: 3.9;melanoma: 1.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 6.4;HBEC3-KT: 10.1;hTCEpi: 7.3;hTERT-HME1: 13.7;T-47d: 4.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA023120, HPA078597" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "HPA023120: AB_10959300, HPA078597: AB_2732385" "unprognostic (2.40e-1)" "unprognostic (3.01e-2)" "unprognostic (1.87e-3)" "unprognostic (2.09e-4)" "unprognostic (1.07e-2)" "unprognostic (4.06e-2)" "unprognostic (3.56e-4)" "unprognostic (3.60e-1)" "unprognostic (4.65e-2)" "unprognostic (3.82e-2)" "unprognostic (3.72e-1)" "unprognostic (3.66e-5)" "unprognostic (9.81e-2)" "unprognostic (2.55e-1)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" 0.0 0.0 0.5 0.0 0.3 0.0 1.6 1.9 2.1 0.6 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.4 0.2 0.1 0.7 0.1 0.0 0.1 0.3 0.0 0.1 56.2 0.0 0.0 0.1 0.0 0.0 0.8 1.0 0.0 0.0 0.0 1.2 0.0 1.8 0.5 6.4 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.4 0.1 0.5 0.2 0.2 0.1 2.9 0.4 0.8 10.1 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.3 0.1 13.7 0.0 0.0 0.9 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.7 0.0 0.0 4.4 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 1.9 2.1 0.7 0.4 0.8 0.7 0.7 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 2.1 1.2 0.0 0.0 0.6 0.5 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.4 0.1 0.1 0.2 0.0 0.0 1.2 0.9 1.2 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.8 1.7 0.3 1.8 1.1 0.0 0.0 0.0 0.6 AMACR "P504S, RACE" ENSG00000242110 "Alpha-methylacyl-CoA racemase" Q9UHK6 5 33986165-34008104 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 134.3;liver: 180.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.7;Hepatocytes: 21.6;Late spermatids: 21.6;Proximal tubular cells: 38.5" "Group enriched" "Detected in all" 4 "liver cancer: 8.8;prostate cancer: 34.5;renal cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 175.4;U-266/84: 98.0" "Low region specificity" "Detected in all" "CAB001809, HPA019527, HPA020912" Enhanced Supported "Vesicles,Plasma membrane" NA NA 70000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "CAB001809: AB_2305454, HPA019527: AB_10669651, HPA020912: AB_10670034" "unprognostic (8.96e-2)" "unprognostic (5.20e-3)" "prognostic favorable (7.11e-4)" "unprognostic (9.55e-2)" "unprognostic (1.39e-1)" "unprognostic (9.12e-3)" "unprognostic (1.68e-1)" "unprognostic (5.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-1)" "unprognostic (5.59e-5)" "unprognostic (1.95e-2)" "unprognostic (5.52e-3)" "unprognostic (6.32e-2)" "unprognostic (3.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" 8.6 15.0 5.9 5.0 5.5 3.0 6.4 4.6 6.0 6.5 4.6 40.0 18.0 4.7 9.6 15.6 6.2 20.5 10.1 5.4 7.8 134.3 180.6 9.2 3.6 5.9 6.4 7.8 13.8 13.0 5.7 7.7 6.6 39.3 42.9 12.0 60.7 12.5 19.2 4.9 15.9 7.0 5.8 5.4 34.8 4.3 8.4 4.8 8.3 14.9 5.6 8.8 8.5 5.8 12.7 20.2 11.1 14.3 7.7 11.9 19.1 16.6 12.2 7.6 5.7 66.1 15.1 4.1 8.7 23.6 28.6 5.8 2.8 12.0 7.7 12.7 10.9 9.8 13.7 19.0 5.4 6.0 3.0 18.1 6.0 9.7 3.6 10.7 8.5 8.3 3.8 14.7 22.4 9.6 5.0 7.6 10.0 9.4 32.9 6.0 18.6 6.5 33.2 62.4 6.1 8.7 27.6 19.3 16.9 9.1 14.9 5.9 15.6 24.6 5.4 6.2 13.6 175.4 98.0 7.4 7.0 12.1 18.8 0.3 6.0 9.3 8.3 8.0 7.0 7.1 7.2 6.4 8.9 5.2 6.6 4.8 10.0 8.7 14.2 4.6 7.9 6.0 5.9 5.5 4.6 6.0 5.4 7.8 5.9 6.4 6.6 5.8 8.4 5.8 0.8 3.2 4.1 0.0 2.2 0.4 0.4 0.9 1.8 4.3 1.4 0.9 1.1 8.6 3.7 1.8 0.0 1.0 2.2 19.7 5.9 0.8 8.9 2.3 1.2 3.0 4.2 2.1 0.0 3.8 1.0 2.9 4.1 1.5 0.0 1.2 1.1 21.6 1.1 5.0 0.0 5.1 4.1 0.9 0.2 21.6 0.6 1.2 0.0 0.0 1.5 9.3 3.1 0.0 0.0 2.6 4.5 2.2 1.6 0.6 4.7 38.5 3.1 0.9 0.0 1.7 3.7 0.7 0.7 3.4 0.6 0.3 1.5 1.2 4.4 0.4 BPGM ENSG00000172331 "Bisphosphoglycerate mutase" P07738 7 134646811-134679816 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Congenital erythrocytosis, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 87.3" "Group enriched" "Detected in all" 4 "Distal tubular cells: 129.1;Erythroid cells: 456.6;Syncytiotrophoblasts: 368.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 118.2;RT4: 186.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016493, HPA028735" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA 81000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 15: RT4 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA016493: AB_1845414, HPA028735: AB_10600791" "unprognostic (2.56e-1)" "prognostic favorable (7.95e-4)" "unprognostic (3.19e-1)" "unprognostic (3.94e-1)" "unprognostic (1.78e-1)" "unprognostic (5.22e-2)" "unprognostic (3.81e-3)" "unprognostic (1.96e-1)" "unprognostic (7.74e-2)" "unprognostic (4.67e-3)" "unprognostic (7.42e-2)" "unprognostic (5.69e-2)" "prognostic favorable (1.54e-8)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (2.73e-1)" "unprognostic (3.78e-2)" 11.4 12.6 16.3 9.1 17.1 87.3 12.4 17.9 20.5 12.5 15.8 12.9 8.4 9.6 18.5 26.9 8.5 12.9 13.5 16.5 19.0 35.1 13.1 14.0 11.1 17.9 17.8 7.1 8.4 35.3 18.1 47.0 18.2 13.5 10.0 19.9 17.8 17.9 37.8 10.7 8.0 12.1 19.6 12.5 11.9 14.7 17.7 16.3 11.9 27.0 26.2 39.0 17.2 18.5 14.0 16.3 21.7 29.6 24.3 14.4 21.9 41.3 49.9 15.7 23.2 6.5 18.5 17.1 12.0 23.2 30.9 11.2 23.3 22.7 27.6 118.2 19.9 9.8 15.4 7.8 16.7 18.8 12.4 14.2 20.0 29.7 16.0 24.0 58.0 20.8 28.8 20.9 37.8 6.6 30.7 26.0 22.7 27.7 15.3 23.2 15.5 12.4 36.1 186.8 18.7 31.1 19.3 23.1 21.7 23.1 15.1 11.8 44.7 25.1 6.0 33.7 33.9 33.9 41.2 21.5 43.3 17.7 43.7 61.1 16.4 48.9 23.3 22.2 16.7 19.3 15.0 20.7 17.5 18.9 20.7 21.1 30.2 18.5 23.0 11.4 21.1 23.6 16.3 17.1 17.9 20.5 16.5 19.0 17.9 17.8 18.2 19.6 17.7 18.5 17.6 9.6 25.5 6.5 15.7 39.0 18.5 60.6 10.8 19.2 15.9 18.7 25.0 18.6 52.3 27.6 2.1 44.5 43.0 5.0 129.1 45.9 3.4 10.0 7.0 18.8 13.1 456.6 8.0 18.2 32.7 17.0 4.1 8.5 24.7 6.6 10.0 4.7 15.1 20.2 9.3 4.6 36.7 11.7 10.5 7.2 10.2 11.8 23.2 5.6 15.7 25.6 47.4 7.5 11.6 49.0 4.6 12.0 14.2 26.0 5.5 68.8 50.5 13.5 6.6 12.0 22.1 33.9 21.8 13.5 13.2 368.9 25.0 7.8 4.8 19.2 CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "CF transmembrane conductance regulator" P13569 7 117287120-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.6;intestine: 42.7;pancreas: 210.7" "Group enriched" "Detected in many" 4 "Ductal cells: 485.4;Ionocytes: 252.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "CACO-2: 29.5;MOLT-4: 98.9;U-266/70: 49.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB001951: , HPA021939: AB_1846578, HPA079652: " "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" 0.4 0.0 0.5 4.7 2.0 0.0 0.4 0.7 1.3 8.5 0.0 42.7 36.2 1.1 1.1 0.8 2.2 54.6 0.1 0.3 0.7 2.1 1.6 8.2 0.0 1.1 0.7 0.0 210.7 0.2 0.1 0.6 0.7 2.2 40.7 0.0 21.5 0.5 0.0 1.9 19.9 2.0 1.7 0.0 3.1 1.7 1.0 0.1 0.1 0.0 0.3 0.7 0.0 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 98.9 0.1 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 49.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.7 1.3 0.3 0.7 1.1 0.7 0.7 1.7 1.0 2.9 0.0 6.4 65.6 0.0 0.5 0.0 2.0 2.6 0.0 0.5 0.5 0.0 2.4 55.8 17.8 0.0 0.0 0.0 0.0 45.8 0.0 485.4 3.2 9.6 1.2 0.4 7.2 0.0 2.2 4.5 0.0 0.3 4.1 19.8 1.3 0.1 0.0 0.4 0.0 0.0 1.1 13.9 252.3 0.0 0.0 2.6 0.3 0.1 0.0 1.0 6.7 0.5 0.0 0.5 23.8 14.8 86.4 0.0 0.0 4.0 8.6 0.0 5.6 0.0 0.0 0.0 1.6 2.2 0.5 0.0 0.0 0.0 0.3 0.1 87.3 5.8 CRELD1 "AVSD2, CIRRIN" ENSG00000163703 "Cysteine rich with EGF like domains 1" Q96HD1 3 9933816-9945406 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 110.3;hTERT-RPE1: 77.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026964 Uncertain Approved Nucleoli,Cytosol "Intracellular and membrane" NA NA 19000000 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Nucleoli "HPA026964: AB_10602210" "unprognostic (3.06e-2)" "unprognostic (1.08e-1)" "unprognostic (2.69e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (8.07e-4)" "unprognostic (3.03e-1)" "unprognostic (3.59e-1)" "unprognostic (2.85e-2)" "unprognostic (1.24e-2)" "unprognostic (1.19e-1)" "unprognostic (1.92e-2)" "unprognostic (4.59e-2)" "unprognostic (1.14e-2)" "unprognostic (6.31e-2)" "unprognostic (9.51e-2)" "unprognostic (2.89e-1)" "unprognostic (3.78e-2)" 32.7 37.3 63.6 11.4 63.5 9.3 24.8 69.1 94.4 27.7 59.1 57.5 14.0 31.3 17.0 18.0 34.9 16.5 73.2 63.9 65.7 43.0 57.1 27.5 12.4 64.7 63.0 32.5 27.6 22.7 70.9 17.9 66.3 47.6 12.1 16.4 26.3 34.5 48.9 20.1 25.9 22.2 58.6 28.6 35.6 23.6 65.5 10.5 67.6 26.4 9.2 33.6 24.4 68.2 6.4 8.1 19.3 8.8 30.1 17.6 110.3 26.7 8.0 6.1 11.7 11.1 20.7 8.4 57.6 17.7 27.7 4.5 10.4 17.6 4.9 15.2 9.2 7.3 15.2 28.2 68.7 3.3 29.3 21.7 32.3 15.2 13.6 77.2 28.8 11.1 9.5 10.4 6.1 15.5 3.6 19.3 5.7 30.1 6.6 4.8 3.1 21.6 25.9 9.9 6.9 26.7 12.6 10.3 24.3 27.5 27.9 17.0 21.7 12.1 19.5 16.2 6.3 10.7 14.2 15.2 27.3 7.8 13.0 12.3 10.2 9.3 11.9 9.8 12.2 7.9 8.9 11.5 6.9 8.7 11.3 10.4 1.8 13.8 12.9 12.3 7.2 9.5 63.6 63.5 69.1 94.4 63.9 65.7 64.7 63.0 66.3 58.6 65.5 68.2 24.7 19.2 17.5 43.4 14.1 9.7 26.2 48.5 15.9 21.5 17.5 15.0 41.9 31.5 24.0 16.5 16.7 23.7 15.1 10.9 7.9 19.6 6.8 10.3 7.0 20.2 27.0 7.8 38.0 4.4 11.5 20.1 19.4 12.9 21.0 18.8 19.2 14.9 20.6 32.0 37.1 19.1 38.7 8.8 9.0 10.1 32.0 10.0 12.4 15.0 13.9 18.3 27.8 14.6 21.7 8.7 20.4 26.4 15.3 31.4 18.8 11.1 13.2 15.8 26.3 11.0 17.1 68.0 26.5 9.6 12.4 22.2 15.4 11.2 15.4 20.2 CRELD2 MGC11256 ENSG00000184164 "Cysteine rich with EGF like domains 2" Q6UXH1 22 49918167-49927540 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 349.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000603, CAB025604" Approved "Intracellular and membrane" NA NA 480000 "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 55: Plasma cells - Humoral immune response" "CAB025604: , HPA000603: AB_1078565" "unprognostic (1.12e-1)" "unprognostic (7.35e-2)" "unprognostic (1.10e-1)" "prognostic favorable (2.42e-7)" "unprognostic (5.04e-2)" "unprognostic (5.43e-2)" "unprognostic (3.21e-3)" "unprognostic (2.71e-1)" "unprognostic (3.60e-1)" "unprognostic (1.24e-1)" "unprognostic (2.57e-2)" "unprognostic (7.97e-2)" "prognostic unfavorable (1.34e-9)" "unprognostic (6.13e-2)" "unprognostic (3.01e-1)" "unprognostic (7.30e-2)" "unprognostic (4.02e-1)" 29.0 28.5 17.7 25.8 20.6 18.1 24.1 19.3 20.1 25.4 19.2 29.6 26.4 31.5 41.8 26.6 28.2 13.6 33.0 18.3 21.4 26.7 97.8 31.5 19.1 22.1 19.9 23.5 123.3 13.0 65.5 14.4 21.5 27.3 16.4 7.7 39.5 17.1 15.8 17.0 26.8 15.8 19.0 40.3 46.0 43.2 24.9 15.4 67.4 7.6 15.2 27.1 21.3 21.9 37.5 25.5 29.3 96.6 30.6 34.6 39.1 76.4 46.0 41.9 35.5 44.7 44.0 20.4 59.6 66.2 42.3 36.4 37.1 38.3 18.0 11.0 60.1 11.2 37.3 55.8 126.1 44.1 41.4 31.8 33.6 36.4 30.6 29.5 42.9 21.8 16.5 79.5 31.8 119.3 17.2 46.2 21.1 73.9 54.7 41.1 51.9 46.4 20.3 33.6 19.0 53.5 64.9 75.2 32.0 19.3 30.8 51.8 32.7 35.5 59.2 33.1 23.9 65.4 16.9 17.9 52.6 32.5 57.3 33.5 12.4 17.2 17.2 14.9 17.7 29.2 14.9 23.2 13.7 28.1 12.4 10.2 6.4 35.4 8.9 52.2 11.3 12.9 17.7 20.6 19.3 20.1 18.3 21.4 22.1 19.9 21.5 19.0 24.9 21.9 42.4 6.4 16.1 12.7 82.6 32.8 34.4 49.0 10.2 34.7 35.3 34.2 17.7 31.5 39.6 9.2 25.0 32.4 65.6 45.6 7.9 41.2 112.5 28.4 41.5 32.2 39.9 12.4 9.7 63.2 120.5 56.8 50.4 37.0 36.2 27.0 47.2 63.9 74.6 25.2 10.9 136.3 26.4 25.7 47.0 25.8 44.1 33.8 96.0 6.5 27.8 41.7 80.3 9.5 16.2 51.2 35.1 41.3 349.6 82.4 28.2 16.6 37.4 32.0 13.1 25.7 39.7 143.5 104.8 21.6 30.7 55.1 53.0 41.0 55.7 43.8 CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 89.7;intestine: 83.4;liver: 146.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 91.4;Cytotrophoblasts: 116.2;Hepatocytes: 58.3;Oligodendrocytes: 68.5;Proximal enterocytes: 134.6;Syncytiotrophoblasts: 240.9" "Cancer enhanced" "Detected in many" "renal cancer: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "OE19: 16.9;RT4: 62.3;SK-BR-3: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "unprognostic (7.29e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (5.54e-7)" "unprognostic (4.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.25e-1)" "unprognostic (9.70e-2)" 1.2 0.4 18.3 1.2 22.1 0.1 9.3 23.6 19.1 2.3 8.4 19.0 34.1 1.0 0.8 13.1 0.9 2.0 89.7 14.7 19.4 3.0 146.2 1.4 0.2 20.7 20.7 0.0 2.2 0.0 0.9 22.3 18.9 3.3 21.3 3.5 14.5 0.7 25.3 8.9 83.4 1.8 20.2 0.1 4.7 0.6 28.0 0.5 0.1 6.4 0.7 5.8 3.6 21.8 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.7 0.1 1.2 0.3 2.8 0.0 0.8 0.0 3.5 0.9 0.0 0.9 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.1 0.5 0.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 3.2 0.0 0.0 1.5 16.9 2.6 0.0 6.3 0.0 3.4 62.3 0.9 3.8 0.1 16.4 0.6 0.1 4.1 0.0 0.0 2.2 2.5 0.0 0.9 1.9 0.1 0.0 0.5 0.0 6.9 0.0 0.0 0.0 0.1 0.0 0.6 0.8 0.3 0.2 0.0 0.4 2.9 2.6 0.0 0.4 0.0 0.6 0.0 0.4 18.3 22.1 23.6 19.1 14.7 19.4 20.7 20.7 18.9 20.2 28.0 21.8 0.0 3.2 4.1 35.6 0.7 0.4 1.7 5.5 7.4 0.0 5.1 3.0 91.4 11.5 28.9 0.0 0.0 116.2 0.1 26.4 0.0 9.5 22.7 3.1 1.7 1.3 9.0 0.0 0.1 0.9 9.3 2.3 4.1 7.7 0.0 1.5 0.0 58.3 7.0 0.0 0.4 18.7 6.1 0.8 0.3 23.3 0.0 0.2 0.0 1.9 0.6 12.5 0.0 29.7 68.5 2.0 18.1 0.0 0.3 1.5 134.6 2.5 20.1 0.9 0.0 0.7 1.0 0.3 0.2 7.3 2.3 240.9 0.2 0.4 24.1 2.1 CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 101.3;stomach 1: 120.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.0;Gastric mucus-secreting cells: 110.6;Intestinal goblet cells: 29.2;Langerhans cells: 73.0;Proximal enterocytes: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.7;myeloid DC: 84.4" "Group enriched" "Detected in many" 131 "dendritic cells: 84.4;monocytes: 24.7" "Cell line enhanced" "Detected in many" "A549: 99.4;CACO-2: 49.8;HaCaT: 50.3;NTERA-2: 69.6;OE19: 158.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA049227: AB_2680681, HPA069248: AB_2732128" "unprognostic (1.49e-2)" "unprognostic (7.45e-2)" "unprognostic (2.45e-2)" "unprognostic (6.03e-2)" "unprognostic (3.93e-2)" "unprognostic (7.46e-2)" "unprognostic (1.27e-2)" "unprognostic (4.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.54e-2)" "unprognostic (6.25e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" 1.8 1.1 1.4 6.7 1.4 1.8 0.9 3.1 1.5 2.7 1.2 26.7 101.3 0.5 0.2 14.5 6.3 5.5 0.5 1.3 4.1 1.1 1.4 7.1 1.7 6.3 10.0 0.3 0.6 0.7 1.2 1.6 6.1 1.3 18.6 0.2 5.0 0.9 0.2 3.7 65.3 1.7 2.2 6.1 120.4 0.8 3.6 3.2 0.6 0.2 13.2 3.6 4.0 2.5 3.8 99.4 0.0 0.1 0.0 0.0 4.5 0.6 0.8 1.0 0.2 49.8 13.6 0.2 10.4 0.7 0.1 50.3 16.6 25.0 0.4 0.0 0.3 12.9 5.1 19.1 19.4 0.0 0.4 0.8 1.4 1.4 0.8 0.2 0.8 4.3 5.8 0.2 0.0 2.0 0.3 0.2 69.6 158.6 12.5 0.2 0.0 0.9 1.5 20.4 0.1 0.6 9.1 0.0 0.0 27.8 12.2 4.7 10.6 0.1 4.0 1.7 0.0 0.5 0.0 0.0 0.5 2.1 0.1 0.0 24.7 0.0 0.0 5.9 0.4 0.0 0.0 0.1 84.4 0.0 0.0 0.0 0.2 0.1 3.7 3.2 0.0 11.4 1.4 1.4 3.1 1.5 1.3 4.1 6.3 10.0 6.1 2.2 3.6 2.5 0.3 0.0 6.9 1.0 0.7 2.5 2.0 18.2 23.3 0.0 0.1 0.3 1.2 0.0 7.6 1.8 0.0 24.9 0.1 31.0 0.0 0.7 0.3 7.4 0.3 0.4 0.0 0.0 0.4 1.0 1.1 0.8 110.6 0.3 1.3 0.1 0.4 0.0 14.5 0.0 0.5 29.2 0.0 5.7 73.0 0.0 0.0 16.0 0.0 1.0 7.2 0.0 0.0 0.5 0.1 23.7 22.3 0.0 0.4 0.5 50.7 0.2 10.8 0.0 0.0 0.3 0.9 0.1 0.4 4.0 2.8 10.3 0.3 0.0 14.1 0.5 DCT TYRP2 ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436811-94479682 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 107.4" "Cell type enriched" "Detected in some" 23 "Melanocytes: 3552.1" "Cancer enriched" "Detected in some" 215 "melanoma: 155.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 272 "SK-MEL-30: 257.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Vesicles "CAB017634: AB_1130818, HPA010742: , HPA010743: AB_1847519, HPA010800: AB_1847520" "unprognostic (5.99e-2)" "unprognostic (1.67e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (3.64e-3)" "unprognostic (1.06e-2)" "unprognostic (6.18e-5)" "unprognostic (6.97e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-3)" "unprognostic (2.42e-1)" 0.4 0.4 0.6 0.0 1.0 0.1 3.0 0.4 0.7 0.2 0.2 0.3 0.0 0.3 0.9 0.0 0.9 0.1 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.6 0.6 0.4 0.4 0.0 1.6 0.0 0.5 0.3 0.0 0.9 1.5 0.3 0.4 107.4 0.1 0.1 0.6 0.1 0.1 0.6 0.6 0.5 0.2 0.1 0.0 0.2 0.3 0.5 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 257.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.7 0.6 0.6 0.6 0.6 0.5 0.6 0.6 0.5 0.0 0.0 0.0 23.5 0.0 152.3 0.1 0.0 0.0 1.0 0.3 0.5 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.5 0.1 1.2 0.0 0.0 16.1 0.2 0.0 1.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 25.5 23.8 0.9 0.0 3552.1 1.9 0.0 3.5 0.0 6.6 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.5 1.0 0.5 0.8 0.0 33.4 0.0 0.9 0.1 0.0 0.0 DSE "DS-Epi1, DSEPI, SART2" ENSG00000111817 "Dermatan sulfate epimerase" Q9UL01 6 116254173-116444861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 112.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 5.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014764 Uncertain "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "HPA014764: AB_1856587" "unprognostic (1.28e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (3.23e-3)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.02e-2)" "unprognostic (7.81e-2)" "prognostic unfavorable (6.34e-4)" "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (6.19e-3)" "unprognostic (2.54e-2)" "unprognostic (2.06e-1)" "unprognostic (1.10e-2)" 27.8 10.7 3.6 26.8 4.5 18.4 18.3 3.9 4.4 13.8 10.4 7.7 6.4 10.5 8.3 13.7 14.6 14.9 12.4 3.2 4.3 8.6 11.3 15.3 16.4 7.0 5.8 13.8 3.8 11.1 6.0 23.1 5.6 8.5 8.0 3.5 6.9 10.2 6.9 13.8 9.0 15.0 4.6 18.6 6.4 6.1 8.5 10.3 6.6 10.7 9.7 19.7 14.3 5.9 32.7 7.0 23.6 22.2 62.0 40.7 26.5 37.6 88.2 46.4 67.4 0.2 8.9 0.9 3.3 66.3 46.4 60.8 3.3 88.7 60.1 33.9 14.6 2.2 9.8 0.3 69.0 1.5 1.7 86.8 37.4 51.5 50.0 24.0 27.7 8.3 0.8 14.4 22.4 1.0 4.4 1.8 12.7 0.2 1.8 5.6 21.6 15.6 30.4 2.2 7.8 5.9 36.4 0.1 0.8 16.2 0.3 3.9 10.5 46.4 13.4 11.8 30.6 3.1 1.1 1.6 24.6 4.0 5.5 0.4 2.0 0.1 0.6 2.5 0.3 2.0 0.5 0.3 5.9 2.1 0.6 0.3 1.6 0.1 1.6 2.7 0.1 0.8 3.6 4.5 3.9 4.4 3.2 4.3 7.0 5.8 5.6 4.6 8.5 5.9 9.4 16.0 4.1 64.9 15.4 52.0 26.4 42.2 78.6 6.3 7.4 10.7 8.3 2.8 20.7 3.7 0.0 2.9 16.5 0.3 7.9 4.8 52.2 11.0 21.9 15.4 1.2 11.4 46.8 8.5 7.0 73.7 3.6 3.1 22.8 100.9 56.4 5.7 39.8 1.7 48.9 0.6 8.2 83.6 77.1 24.9 55.0 112.2 10.6 51.5 79.4 3.4 5.2 73.4 86.4 13.6 0.4 30.1 8.9 32.0 0.4 7.7 30.3 3.0 32.9 16.4 33.4 6.1 5.5 76.6 39.9 4.9 14.0 17.2 1.0 51.0 EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "EBP cholestenol delta-isomerase" Q15125 X 48521799-48528716 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease variant, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 328.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 674.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" 10.2 73.3 16.7 17.1 17.2 48.3 17.4 18.5 17.8 19.4 22.0 50.6 85.5 11.0 17.3 41.3 14.3 10.5 32.5 16.8 18.7 44.0 328.5 24.4 18.8 24.4 16.6 12.7 26.0 44.0 7.2 8.2 24.2 40.6 57.5 10.7 25.0 11.7 9.5 27.8 54.2 14.9 15.8 16.9 31.6 14.2 15.9 28.2 14.4 10.6 32.7 14.1 23.3 16.0 224.5 96.4 107.4 77.0 74.5 39.2 50.5 48.2 43.6 64.3 93.9 169.9 382.7 115.9 35.2 41.3 83.5 230.3 217.5 293.8 49.8 85.8 149.7 50.1 115.2 139.3 57.8 179.2 138.2 51.3 108.6 112.9 86.4 22.5 46.5 98.1 77.6 119.5 50.7 163.7 119.1 199.9 118.2 88.3 199.1 93.8 10.3 363.7 175.6 68.8 110.0 59.6 175.4 122.6 31.2 91.5 122.9 71.1 46.6 33.1 56.2 132.9 63.1 47.5 72.1 107.7 78.7 239.7 40.6 96.1 37.7 97.1 129.4 53.4 104.5 71.5 90.5 116.7 53.5 57.2 76.5 99.7 7.3 63.9 57.2 105.4 103.1 93.6 16.7 17.2 18.5 17.8 16.8 18.7 24.4 16.6 24.2 15.8 15.9 16.0 15.2 32.1 49.8 2.9 38.9 37.1 58.2 245.6 23.3 23.8 57.8 26.2 49.9 77.2 116.6 53.3 8.4 55.9 74.5 140.3 39.2 91.7 10.5 30.5 14.7 26.1 30.0 48.8 7.4 239.1 113.0 21.4 36.2 56.5 40.6 41.2 27.1 674.6 65.0 8.4 10.3 96.8 93.6 30.2 36.0 11.8 13.4 31.9 37.4 4.7 34.8 19.3 101.0 5.0 5.1 156.7 137.3 14.7 54.4 46.4 171.9 99.7 34.8 23.3 13.1 12.5 23.6 8.7 22.7 47.6 45.5 37.5 57.1 128.7 149.1 71.1 ECI1 DCI ENSG00000167969 "Enoyl-CoA delta isomerase 1" P42126 16 2239402-2252300 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 301.3;Hepatocytes: 246.5;Proximal tubular cells: 272.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041746, HPA043227" Enhanced Enhanced Mitochondria NA NA 7300000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041746: AB_10960693, HPA043227: AB_10960273" "unprognostic (4.99e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.75e-1)" "unprognostic (2.92e-3)" "unprognostic (8.90e-2)" "unprognostic (2.85e-2)" "prognostic favorable (1.07e-4)" "unprognostic (1.98e-1)" "unprognostic (2.17e-1)" "unprognostic (5.14e-3)" "unprognostic (6.32e-2)" "unprognostic (2.66e-2)" "prognostic favorable (8.99e-8)" "unprognostic (2.61e-2)" "unprognostic (3.31e-1)" "unprognostic (1.97e-1)" "unprognostic (6.08e-3)" 51.5 57.3 35.9 12.7 39.2 19.6 52.0 38.6 45.9 46.2 61.6 74.0 59.9 44.9 10.6 57.0 50.7 11.3 189.7 32.1 38.0 123.2 235.7 37.2 13.8 39.1 37.8 38.6 74.7 43.8 50.4 14.6 35.0 56.6 15.0 12.8 78.7 24.2 220.6 49.7 58.8 9.3 37.3 35.3 69.5 18.2 42.0 13.4 105.0 87.8 9.5 50.3 43.6 36.5 29.5 68.0 25.7 107.4 9.6 13.6 96.6 29.5 19.1 23.1 33.7 120.0 88.0 42.3 71.2 17.7 16.9 71.6 29.6 27.5 3.2 74.2 157.1 12.9 61.7 151.7 87.3 38.6 6.0 25.2 63.1 18.9 41.7 16.4 23.6 1.1 71.7 87.1 8.0 119.1 4.0 57.8 60.1 46.8 68.8 134.3 27.7 207.1 45.5 32.5 88.8 56.2 70.0 131.4 92.7 12.6 84.7 67.7 19.6 18.4 68.0 19.9 33.0 95.8 61.0 72.2 23.9 35.4 26.2 1.7 3.6 1.6 1.9 3.8 3.1 4.4 2.8 1.6 3.0 4.9 3.4 2.9 2.0 3.6 2.5 3.6 4.0 0.8 35.9 39.2 38.6 45.9 32.1 38.0 39.1 37.8 35.0 37.3 42.0 36.5 47.1 3.2 28.2 13.4 28.0 21.3 115.6 11.3 21.1 53.2 77.2 95.1 92.3 94.4 15.0 77.3 43.8 179.6 20.5 151.7 301.3 35.1 10.9 128.2 54.8 28.2 45.5 61.7 4.2 36.9 80.7 33.1 33.1 122.8 5.7 62.2 34.2 246.5 47.9 21.9 6.7 105.9 20.3 31.0 23.8 5.3 24.5 29.8 39.2 4.7 17.5 89.9 5.2 13.0 10.0 33.2 91.1 24.0 36.8 72.8 176.1 272.3 14.6 77.6 0.0 73.4 42.7 6.3 19.6 32.9 22.3 109.9 21.7 50.2 104.7 110.5 ECI2 "ACBD2, DRS1, HCA88, PECI" ENSG00000198721 "Enoyl-CoA delta isomerase 2" O75521 6 4115693-4135597 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 422.7" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 293.6;Distal tubular cells: 428.4;Proximal tubular cells: 577.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022130, HPA031626" Enhanced Enhanced Peroxisomes,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Peroxisomes, Mitochondria" "HPA022130: AB_1855176, HPA031626: AB_2673965" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (1.71e-2)" "unprognostic (1.04e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.17e-3)" "unprognostic (4.97e-2)" "unprognostic (9.49e-2)" "unprognostic (3.95e-3)" "unprognostic (3.17e-2)" "unprognostic (5.75e-2)" "prognostic favorable (2.04e-6)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (8.45e-2)" "unprognostic (1.34e-1)" 53.6 123.6 43.9 21.0 47.7 21.5 65.0 46.5 63.7 60.0 50.5 53.3 64.0 44.9 102.1 26.7 49.2 40.1 150.9 42.4 47.8 236.0 422.7 28.6 20.0 45.0 45.6 71.4 159.8 53.2 52.6 37.7 44.2 45.2 55.4 31.8 29.9 36.3 198.4 22.7 59.6 35.5 45.3 30.1 103.5 30.9 49.0 33.5 37.0 236.4 21.8 31.6 26.8 45.5 82.8 45.1 72.8 161.0 89.7 131.4 8.8 114.0 116.7 122.1 107.7 34.0 12.4 3.6 139.6 126.0 111.0 41.6 83.6 67.4 179.5 30.4 95.8 44.0 59.7 186.8 51.3 40.4 20.7 90.6 40.6 106.2 58.4 166.0 262.9 136.2 146.2 31.1 118.6 33.4 113.9 100.7 49.5 8.1 158.7 108.8 90.8 1.5 67.2 16.8 1.8 33.7 6.8 48.2 107.6 131.0 109.8 18.9 268.6 92.4 49.8 82.7 69.8 46.8 88.7 8.4 47.9 34.7 73.0 19.2 36.4 17.4 41.5 28.4 57.1 45.8 48.8 58.3 58.9 51.9 59.8 59.2 1.2 66.0 43.3 45.3 57.9 41.1 43.9 47.7 46.5 63.7 42.4 47.8 45.0 45.6 44.2 45.3 49.0 45.5 61.0 28.9 25.2 17.0 24.4 18.2 48.6 50.3 22.2 14.3 33.3 41.0 165.8 78.6 40.1 36.8 12.5 293.6 29.3 32.0 428.4 53.2 63.1 60.8 43.1 48.0 52.1 77.6 10.7 175.5 29.0 55.2 34.7 57.0 23.4 68.6 53.9 162.2 64.3 18.5 11.9 41.6 20.3 22.0 19.2 50.6 63.3 23.5 35.6 14.0 34.7 77.7 21.6 8.5 18.2 80.4 37.5 50.8 28.3 24.7 120.6 577.0 83.6 46.4 26.3 46.8 33.9 46.5 35.6 24.9 12.8 101.9 41.2 224.0 60.8 22.3 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "kidney: 144.3;liver: 344.5" "Group enriched" "Detected in many" 10 "Hepatocytes: 289.0;Proximal tubular cells: 147.1" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 10.8 4.3 2.1 3.0 2.9 1.2 4.1 3.9 2.7 3.5 9.2 14.2 21.5 2.8 3.5 5.5 3.6 4.4 10.7 2.1 3.1 144.3 344.5 4.3 2.1 3.2 4.1 2.6 9.9 7.8 1.5 3.2 3.0 6.3 10.8 1.6 5.7 2.2 1.7 4.5 12.9 3.7 2.5 3.7 10.4 2.7 3.1 2.1 6.5 5.6 2.8 3.6 2.1 2.8 12.3 5.0 1.4 0.0 7.3 6.1 1.5 5.7 1.8 3.7 4.1 21.9 7.5 0.0 22.1 5.7 1.4 5.8 0.0 4.8 7.6 16.2 5.2 8.6 1.3 22.5 4.7 1.0 0.2 8.7 6.0 3.7 3.4 5.0 5.5 0.0 5.7 6.1 7.2 6.4 0.2 5.1 3.0 4.3 6.3 0.0 9.9 0.5 15.4 6.8 4.4 6.4 11.2 6.4 10.5 12.1 23.7 10.1 2.6 2.4 3.6 1.9 0.5 1.7 5.6 0.5 0.8 3.9 4.0 0.1 0.9 0.0 0.6 0.8 0.4 0.5 0.4 0.9 2.4 0.0 0.6 1.0 0.0 1.2 0.8 1.0 0.6 0.4 2.1 2.9 3.9 2.7 2.1 3.1 3.2 4.1 3.0 2.5 3.1 2.8 4.9 16.0 10.9 20.9 4.5 1.5 1.4 1.9 1.2 0.7 3.2 2.3 19.2 17.2 3.9 20.2 4.2 8.9 0.4 17.8 19.6 2.1 0.2 6.5 5.1 3.9 7.7 9.7 4.9 6.8 2.9 1.6 8.6 3.1 0.0 6.1 13.6 289.0 4.4 0.0 5.7 12.8 0.0 10.5 1.0 0.7 0.6 2.7 3.6 4.7 9.4 1.9 0.0 3.5 8.0 3.7 9.3 0.4 0.8 2.5 15.0 147.1 4.0 1.2 0.0 1.1 2.4 3.7 4.2 4.9 0.4 1.4 2.2 3.6 10.8 1.8 FKBP10 "FKBP6, FKBP65, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FKBP prolyl isomerase 10" Q96AY3 17 41812680-41823213 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 79.1;Fibroblasts: 100.0;Sertoli cells: 59.2;Smooth muscle cells: 65.3;Theca cells: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 551.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051171, HPA057021" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 22: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA051171: AB_2681371, HPA057021: AB_2683312" "unprognostic (8.30e-2)" "prognostic unfavorable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavorable (3.43e-5)" "prognostic unfavorable (4.99e-4)" 39.4 39.5 20.9 27.1 22.2 0.5 33.5 21.7 26.1 64.0 22.0 29.1 7.6 61.5 16.9 13.9 50.9 46.0 45.6 20.3 22.1 17.7 7.8 37.8 10.9 24.6 21.6 58.4 15.1 48.5 56.7 60.7 22.2 32.6 10.8 6.0 14.7 30.8 7.6 20.4 19.1 55.6 21.9 14.3 18.5 9.0 24.2 4.9 34.9 9.3 4.4 42.2 39.1 21.6 0.7 119.6 110.7 363.3 379.3 441.7 92.0 490.4 497.4 185.6 159.0 62.1 4.8 0.3 6.6 551.9 45.9 0.8 66.7 133.4 77.9 33.0 99.9 48.6 132.1 181.0 411.4 0.0 0.6 476.1 0.5 150.3 115.5 352.6 158.8 0.0 1.9 16.7 157.0 163.2 0.3 0.1 85.4 258.0 38.3 9.9 125.2 15.7 31.7 0.1 26.7 92.1 0.7 349.3 166.0 137.4 54.1 3.1 181.0 219.0 111.5 145.8 76.0 0.8 0.2 0.3 299.7 0.0 213.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.9 22.2 21.7 26.1 20.3 22.1 24.6 21.6 22.2 21.9 24.2 21.6 14.9 0.0 4.8 38.2 0.2 8.5 11.5 2.7 1.2 0.6 10.8 13.2 2.3 1.5 1.4 0.0 0.0 6.1 0.2 0.1 0.0 8.7 0.7 3.0 79.1 34.9 0.0 0.0 0.3 4.7 30.8 100.0 1.5 4.6 0.0 32.9 30.4 0.0 4.7 15.2 0.3 1.3 0.0 0.0 9.7 2.9 46.9 1.5 16.0 15.0 0.0 32.0 0.0 17.1 0.1 2.2 0.1 44.8 0.5 8.2 0.0 0.0 0.1 1.1 59.2 35.2 65.3 0.9 7.6 0.5 5.1 11.9 2.1 54.0 0.6 1.6 FKBP11 FKBP19 ENSG00000134285 "FKBP prolyl isomerase 11" Q9NYL4 12 48921518-48926474 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 495.0" "Cell type enriched" "Detected in many" 4 "Plasma cells: 1153.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 188.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 332.6;Karpas-707: 315.1;OE19: 527.2" "Low region specificity" "Detected in all" HPA041709 Enhanced Approved Centrosome NA NA 170000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Centrosome "HPA041709: AB_10794487" "unprognostic (7.45e-3)" "unprognostic (8.62e-2)" "unprognostic (2.40e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.70e-2)" "unprognostic (2.00e-1)" "unprognostic (3.46e-2)" "unprognostic (1.75e-1)" "unprognostic (7.64e-2)" "unprognostic (3.49e-3)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.15e-1)" "unprognostic (4.51e-1)" "unprognostic (2.79e-1)" "unprognostic (1.54e-1)" 25.6 17.6 4.0 60.2 4.1 34.5 34.5 3.7 4.9 42.4 5.6 57.2 70.8 17.4 86.4 16.2 19.1 25.4 13.1 3.8 12.0 13.8 59.4 23.9 55.4 5.7 6.3 13.8 495.0 4.7 47.2 15.6 5.2 28.9 53.3 2.1 160.2 32.7 2.4 8.0 55.9 26.2 3.8 76.4 70.6 6.1 9.6 16.4 22.9 0.4 77.4 49.2 17.3 4.8 13.6 24.7 3.0 4.5 116.0 141.3 3.8 123.2 183.3 128.0 154.5 78.3 88.3 192.8 2.2 226.8 1.1 60.6 31.6 60.4 77.0 39.1 7.7 6.6 24.7 0.3 332.6 3.2 3.3 165.0 109.8 99.2 171.4 67.2 75.4 53.1 3.0 315.1 49.9 44.7 26.3 5.1 7.4 527.2 33.9 76.5 3.3 280.7 21.0 2.3 35.0 10.6 36.6 66.5 24.4 4.0 2.0 7.0 49.2 21.0 2.8 2.1 2.3 132.3 122.2 108.1 16.1 3.9 33.0 6.0 1.0 2.8 115.7 1.3 188.3 50.5 80.5 92.7 1.9 25.7 38.8 69.9 4.1 26.7 1.1 39.3 33.4 36.3 4.0 4.1 3.7 4.9 3.8 12.0 5.7 6.3 5.2 3.8 9.6 4.8 22.3 16.0 19.1 5.2 229.8 28.3 56.0 48.6 39.3 5.5 45.0 43.3 2.3 30.0 42.8 9.2 39.6 21.5 130.9 23.1 7.9 23.7 18.4 19.2 117.8 32.3 25.1 20.6 5.3 171.7 80.7 64.1 31.6 31.0 12.7 34.0 40.4 96.6 10.9 1.7 3.7 227.7 16.2 15.1 26.1 17.4 27.7 10.1 272.1 0.0 8.0 1.8 158.6 1.5 1.8 59.8 14.3 13.9 1153.9 111.8 14.1 18.0 43.3 14.6 6.6 10.8 88.7 12.0 9.8 23.0 21.3 42.3 145.3 37.5 49.7 45.0 FKBP14 "FKBP22, FLJ20731" ENSG00000106080 "FKBP prolyl isomerase 14" Q9NWM8 7 30010587-30026702 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Deafness, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013329, HPA026829" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" Cytosol "Nucleoplasm, Golgi apparatus" "HPA013329: AB_1848613, HPA026829: AB_10601651" "prognostic unfavorable (1.60e-4)" "unprognostic (1.12e-3)" "unprognostic (6.84e-2)" "unprognostic (1.23e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (6.06e-2)" "unprognostic (7.00e-2)" "unprognostic (6.99e-2)" "unprognostic (2.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.93e-3)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-3)" "prognostic unfavorable (4.25e-4)" 6.5 5.1 3.4 7.0 3.5 4.3 6.4 5.4 3.6 9.9 3.1 4.7 3.0 8.5 10.0 4.7 4.3 6.0 6.8 3.2 3.2 3.1 3.2 4.1 3.1 3.3 3.1 5.4 5.8 6.2 7.7 7.9 3.0 6.8 4.8 7.2 4.3 7.5 2.1 4.7 2.9 13.9 3.0 2.7 4.0 2.2 3.5 1.8 3.3 3.2 3.2 8.9 3.8 3.5 7.0 5.2 14.4 33.6 36.8 46.8 6.5 34.9 32.7 12.0 23.3 4.4 4.3 2.4 16.0 31.0 14.7 14.8 8.1 12.8 23.9 1.3 11.6 5.6 9.2 13.1 18.6 4.0 9.3 29.4 13.1 20.9 24.6 28.2 27.0 3.6 9.2 5.0 21.8 2.9 2.1 4.9 7.5 7.7 9.2 0.1 9.6 8.2 11.8 6.1 3.8 12.5 12.2 27.5 8.8 17.0 6.2 5.3 21.7 12.6 14.6 21.8 14.0 7.6 8.3 4.2 18.0 3.8 40.2 0.5 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.4 0.2 0.0 0.6 0.2 0.1 3.4 3.5 5.4 3.6 3.2 3.2 3.3 3.1 3.0 3.0 3.5 3.5 13.5 19.2 16.0 7.2 7.9 27.4 22.0 15.8 35.9 16.3 13.3 13.0 15.7 5.7 11.7 18.4 27.1 11.6 9.4 5.3 1.9 7.4 0.4 30.4 44.3 12.9 1.2 6.5 19.4 3.7 27.3 40.0 15.3 40.0 2.5 9.1 8.6 6.5 6.0 15.2 12.7 9.7 8.2 2.5 11.2 0.4 13.1 5.7 10.6 10.3 3.6 26.5 2.1 11.6 16.6 5.7 19.0 20.7 43.8 17.8 3.3 2.7 6.0 21.4 6.6 13.8 20.4 1.4 3.4 27.5 18.3 15.7 6.0 20.8 6.1 28.0 FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FKBP prolyl isomerase 1A" P62942 20 1368977-1393164 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Paneth cells: 977.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 675.2;granulocytes: 974.2;monocytes: 1013.4" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 1749.2;TIME: 1929.6" "CAB004639, HPA051798" Uncertain NA NA 12000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004639: AB_425434, HPA051798: AB_2681615" "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "unprognostic (5.22e-3)" "unprognostic (1.28e-2)" "unprognostic (2.66e-1)" "unprognostic (7.18e-3)" "prognostic unfavorable (3.44e-7)" "unprognostic (7.05e-3)" "unprognostic (2.76e-1)" "unprognostic (8.81e-2)" "unprognostic (5.12e-3)" "unprognostic (6.65e-2)" "prognostic unfavorable (6.69e-5)" "unprognostic (1.97e-2)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" 272.7 185.0 138.4 178.8 177.5 167.0 188.2 88.5 163.2 123.0 112.6 158.6 108.9 165.4 150.1 169.8 131.7 104.5 171.4 166.7 115.8 186.7 98.1 235.2 162.7 92.4 98.9 135.1 114.6 123.0 79.5 218.7 95.6 125.4 188.5 11.8 111.0 119.8 110.3 127.3 117.0 225.1 97.8 185.7 118.3 56.9 120.5 188.1 190.9 150.6 202.2 206.8 126.2 118.9 718.1 299.5 172.9 240.3 654.1 771.3 202.9 423.9 337.1 382.7 354.2 278.4 295.2 272.5 149.3 555.7 656.3 337.7 255.1 1007.2 419.7 68.8 170.5 284.2 113.9 473.3 406.4 390.5 168.0 484.7 332.0 410.3 412.6 513.3 1749.2 401.0 271.0 145.8 443.3 125.8 401.9 453.7 307.1 335.3 276.4 307.0 254.1 351.9 540.0 243.4 248.7 173.8 208.0 479.3 728.8 231.8 177.2 293.0 1929.6 1363.6 201.8 278.1 329.5 76.4 168.1 292.9 248.1 332.3 307.5 316.3 870.8 974.2 112.9 1005.8 104.3 128.1 135.5 133.2 675.2 136.2 140.1 132.6 805.0 160.6 1013.4 312.7 195.0 1153.8 138.4 177.5 88.5 163.2 166.7 115.8 92.4 98.9 95.6 97.8 120.5 118.9 779.1 86.6 77.2 0.0 160.6 263.1 211.2 393.3 152.0 17.6 175.6 156.5 59.7 170.1 179.5 172.9 0.0 281.8 148.3 456.2 238.7 432.4 47.7 98.7 183.8 814.8 330.6 196.4 0.0 337.5 702.0 212.2 160.0 122.5 143.5 95.3 623.6 113.5 746.7 35.3 0.0 245.9 329.6 541.8 436.5 52.2 200.0 428.8 241.9 0.0 527.4 52.2 152.4 0.0 0.0 483.6 977.5 162.9 214.8 221.1 210.8 332.1 123.0 11.7 138.1 87.4 224.7 169.3 141.8 329.4 299.3 231.5 150.1 347.3 318.0 245.7 FKBP1B "FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase" ENSG00000119782 "FKBP prolyl isomerase 1B" P68106 2 24049701-24063681 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.9" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;T-reg: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 47.9;NTERA-2: 42.9;SH-SY5Y: 30.7;SuSa: 46.1;TIME: 38.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045572, HPA051798" Uncertain Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "HPA045572: AB_2732521, HPA051798: AB_2681615" "unprognostic (3.01e-3)" "unprognostic (3.35e-1)" "unprognostic (7.05e-2)" "unprognostic (9.89e-3)" "unprognostic (1.47e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-2)" "unprognostic (9.19e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-1)" "unprognostic (9.55e-2)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.43e-2)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" 5.6 4.4 32.5 2.2 36.1 1.6 5.5 26.5 47.9 6.7 23.0 7.1 19.6 4.8 2.7 8.3 3.9 5.4 5.1 39.2 30.9 8.7 6.6 10.5 1.5 27.7 27.6 5.5 7.5 7.0 6.4 4.0 30.3 7.2 3.3 7.7 6.6 6.3 1.4 6.5 6.8 2.7 25.9 2.8 15.0 1.6 32.7 1.6 6.7 1.2 2.3 5.6 8.1 30.5 0.2 2.0 17.2 0.0 10.9 4.7 6.2 5.8 6.0 2.5 3.6 1.2 2.0 0.0 4.3 10.3 15.4 6.8 25.7 20.2 1.6 3.0 16.1 6.0 0.2 47.9 4.5 0.0 14.1 3.9 4.6 5.9 1.1 14.7 16.5 6.8 1.5 0.1 5.9 0.2 2.0 0.0 42.9 1.7 3.0 3.1 1.5 0.2 2.0 1.3 4.1 30.7 0.3 0.1 5.8 46.1 1.2 2.2 38.0 0.0 5.2 0.2 1.4 1.1 0.5 0.0 6.4 0.0 1.3 0.4 0.4 2.2 0.1 0.4 0.0 0.1 0.2 0.2 1.0 1.2 0.0 0.1 0.0 0.1 0.0 0.2 2.8 0.5 32.5 36.1 26.5 47.9 39.2 30.9 27.7 27.6 30.3 25.9 32.7 30.5 9.3 0.0 6.8 2.9 1.8 9.2 14.0 13.7 11.4 2.1 6.5 13.7 0.9 22.8 4.7 7.3 0.0 4.9 2.7 15.8 13.7 27.6 0.6 3.5 5.0 10.9 9.5 7.0 16.9 38.2 31.9 6.9 16.3 7.1 1.3 3.4 15.7 10.2 7.5 1.7 7.8 8.9 2.0 4.0 17.4 2.9 2.8 9.1 28.4 4.7 13.0 31.4 1.0 2.5 1.3 49.8 25.4 4.1 2.4 15.5 10.6 6.8 2.0 3.6 26.3 2.9 10.6 1.6 5.4 9.1 7.4 5.2 4.9 1.4 4.5 19.3 FKBP2 "FKBP-13, FKBP13, PPIase" ENSG00000173486 "FKBP prolyl isomerase 2" P26885 11 64241003-64244132 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 929.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025561, HPA049405" Enhanced Approved "Plasma membrane" "Intracellular and membrane" No No 510000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "CAB025561: , HPA049405: AB_2680749" "unprognostic (4.94e-2)" "unprognostic (1.12e-1)" "unprognostic (5.77e-2)" "unprognostic (2.66e-3)" "unprognostic (7.40e-2)" "unprognostic (1.92e-2)" "unprognostic (8.64e-2)" "unprognostic (1.62e-1)" "unprognostic (3.23e-1)" "unprognostic (5.91e-3)" "unprognostic (5.86e-2)" "unprognostic (7.18e-2)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (5.23e-1)" "unprognostic (2.30e-1)" "unprognostic (3.57e-2)" 64.7 127.6 185.1 77.5 187.6 50.1 58.3 192.7 234.7 113.1 210.8 105.7 136.3 81.1 397.7 68.4 94.4 77.2 117.4 185.0 196.9 122.7 197.3 62.7 70.7 199.9 199.6 75.3 280.1 160.4 200.9 73.1 197.7 92.5 84.2 37.1 208.9 146.7 33.3 60.9 107.3 72.6 183.4 67.5 113.4 74.7 194.3 59.0 187.6 48.4 70.4 85.7 61.6 196.0 101.2 144.8 82.8 165.9 178.5 98.2 94.6 132.9 146.4 108.8 101.4 148.1 257.0 80.8 195.4 186.5 148.2 134.7 70.5 121.0 51.3 101.4 54.5 90.0 196.5 158.3 231.6 74.5 125.5 116.0 169.3 145.4 163.5 156.9 86.9 76.6 61.0 253.6 138.1 186.7 85.1 112.6 92.6 211.1 130.0 70.8 70.9 299.2 198.9 120.7 110.0 91.3 85.4 263.2 147.9 59.5 98.1 69.5 68.9 123.8 100.9 182.8 72.6 128.5 48.6 69.0 156.7 80.6 142.8 276.8 173.1 25.9 178.9 191.2 230.8 170.1 139.2 176.4 172.2 165.0 90.4 131.5 68.6 162.9 162.7 929.1 55.9 126.7 185.1 187.6 192.7 234.7 185.0 196.9 199.9 199.6 197.7 183.4 194.3 196.0 129.5 147.4 168.0 20.9 179.7 164.4 251.0 447.2 125.2 86.4 205.0 185.4 134.7 275.9 270.6 389.9 22.9 279.8 174.4 534.1 412.8 270.8 126.4 212.5 206.3 138.6 342.6 41.4 11.3 254.2 386.9 167.0 179.4 258.5 144.0 146.5 148.5 754.4 228.4 32.0 14.8 508.2 305.2 100.1 201.7 99.0 230.2 140.7 300.6 16.9 151.7 181.7 111.2 11.1 20.6 292.2 424.7 255.1 765.2 315.5 594.7 792.2 241.9 83.3 184.1 138.4 221.3 327.1 282.1 136.6 168.1 620.5 123.6 138.8 339.4 312.0 FKBP3 "FKBP-25, FKBP25" ENSG00000100442 "FKBP prolyl isomerase 3" Q00688 14 45115599-45135319 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 424.4;tongue: 372.0" "Cell type enhanced" "Detected in all" "Late spermatids: 377.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000864, CAB012232, CAB012520" Supported Supported Cytosol NA NA 1300000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB012232: , CAB012520: AB_873554, HPA000864: AB_1078873" "unprognostic (7.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.18e-1)" "unprognostic (9.72e-2)" "unprognostic (1.25e-1)" "unprognostic (9.82e-3)" "unprognostic (3.58e-3)" "unprognostic (2.28e-1)" "unprognostic (5.04e-3)" "unprognostic (1.22e-3)" "unprognostic (7.47e-2)" "unprognostic (6.92e-3)" "unprognostic (1.00e-1)" "unprognostic (3.07e-1)" "unprognostic (1.51e-1)" "unprognostic (1.00e-2)" "unprognostic (1.47e-1)" 40.9 46.8 100.3 35.8 102.3 38.4 50.0 110.1 122.1 38.1 91.8 49.4 44.7 31.4 64.8 54.7 31.4 29.8 109.5 101.9 100.6 66.5 69.7 27.6 53.7 100.7 99.3 35.3 32.8 55.5 56.6 46.9 100.1 57.7 49.1 82.3 37.1 37.9 424.4 38.3 47.8 39.2 99.8 39.9 38.0 52.9 101.4 59.6 40.1 372.0 57.7 43.3 38.6 105.8 161.0 175.3 249.0 132.4 109.0 117.8 98.3 96.2 110.3 149.3 163.5 154.8 134.1 85.1 98.9 110.0 84.1 130.0 188.4 124.8 211.7 123.7 111.0 69.8 138.8 202.6 107.1 122.2 72.8 112.0 127.5 87.2 80.1 136.8 198.0 131.9 102.9 62.1 179.9 196.9 197.5 163.0 126.7 178.3 164.5 187.0 183.7 102.9 242.2 183.7 151.2 59.2 154.8 94.5 156.0 186.4 222.6 89.9 128.7 113.0 195.6 59.9 75.1 104.0 198.8 132.5 68.3 83.0 108.1 23.4 22.4 22.1 18.7 27.3 22.8 29.7 25.0 25.7 33.3 21.8 23.4 26.7 3.6 24.2 29.4 43.0 30.8 20.2 100.3 102.3 110.1 122.1 101.9 100.6 100.7 99.3 100.1 99.8 101.4 105.8 48.3 41.7 46.6 25.8 45.3 47.8 94.4 205.5 45.5 79.3 39.9 46.7 202.5 48.6 101.4 93.8 10.4 320.9 51.2 56.4 252.4 131.1 212.7 55.0 83.3 58.5 56.1 50.9 49.7 73.0 135.4 70.0 36.7 68.1 53.7 75.6 38.2 91.1 131.1 40.4 44.5 71.2 124.1 39.9 43.0 377.4 80.8 53.7 69.4 17.8 110.7 80.7 50.4 21.1 34.3 88.4 53.7 97.8 58.0 76.4 91.8 220.1 73.5 67.4 105.2 71.3 118.5 154.0 111.2 65.0 47.9 165.0 48.8 84.1 96.1 77.6 FKBP4 "FKBP52, FKBP59" ENSG00000004478 "FKBP prolyl isomerase 4" Q02790 12 2794970-2805423 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 372.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006148, CAB017441, HPA062857" Supported Enhanced Nucleoplasm,Cytosol NA NA 480000 "Cluster 44: Non-specific - Transcription" "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "CAB017441: AB_10618759, HPA006148: AB_1078875, HPA062857: AB_2684883" "unprognostic (1.46e-2)" "unprognostic (1.73e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (7.65e-4)" "unprognostic (1.97e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.12e-5)" "prognostic unfavorable (1.44e-4)" "unprognostic (3.43e-1)" "unprognostic (3.25e-2)" "unprognostic (1.72e-1)" "unprognostic (3.14e-1)" "unprognostic (3.89e-2)" "unprognostic (1.59e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (2.22e-1)" 35.4 38.1 92.1 22.3 95.9 24.2 53.1 127.7 372.1 41.7 89.6 35.7 20.3 32.2 44.6 69.3 38.2 24.8 42.7 96.6 104.4 68.1 57.5 38.0 19.8 101.0 101.4 50.4 52.0 47.8 36.1 50.6 106.2 44.4 37.8 52.2 48.1 44.9 69.4 49.8 25.6 40.0 97.8 24.3 58.0 58.4 103.0 25.1 44.4 48.5 29.9 44.6 46.0 141.7 91.6 198.6 56.2 94.9 68.5 40.1 268.3 87.5 31.2 141.2 95.0 199.1 108.3 120.9 24.5 56.6 98.2 121.9 353.3 118.5 168.2 222.6 226.1 133.2 141.8 71.4 52.6 105.5 35.0 36.5 106.6 167.2 165.9 84.0 83.5 119.8 124.9 166.4 57.6 261.5 186.2 94.9 480.0 266.5 141.2 110.0 98.7 72.4 119.5 114.2 80.7 116.0 101.6 272.7 45.3 348.8 368.0 70.3 44.9 69.1 216.4 78.6 224.1 40.9 67.9 177.0 61.4 154.7 72.2 17.0 11.5 6.7 12.5 10.5 13.9 14.0 11.0 11.9 6.4 14.3 11.3 13.5 1.5 9.2 15.5 5.6 11.0 11.1 92.1 95.9 127.7 372.1 96.6 104.4 101.0 101.4 106.2 97.8 103.0 141.7 31.9 6.4 11.5 10.1 39.1 143.9 261.5 38.5 80.8 60.3 133.9 96.3 13.1 54.3 26.8 53.3 75.0 186.1 27.2 111.0 154.6 82.0 125.4 49.7 47.4 43.5 106.1 77.8 12.9 25.9 117.3 42.6 41.8 74.5 38.2 45.3 20.7 49.3 62.0 97.6 15.5 124.9 63.1 17.5 102.1 40.9 34.8 67.7 92.5 4.7 40.2 48.3 25.7 10.1 17.6 60.3 100.1 38.7 47.3 272.4 77.3 141.7 21.1 63.4 85.5 28.3 117.2 149.4 74.4 111.5 132.8 223.3 74.0 38.6 148.7 147.3 FKBP5 "FKBP51, FKBP54, P54, PPIase, Ptg-10" ENSG00000096060 "FKBP prolyl isomerase 5" Q13451 6 35573585-35728583 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 892.7;tongue: 925.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 759.3;ASC TERT1: 468.5;HHSteC: 593.0;HSkMC: 718.3;hTCEpi: 368.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009315, HPA031092, HPA031093, HPA031095" Enhanced Enhanced Nucleoplasm No No 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB009315: AB_2278350, HPA031092: AB_10600195, HPA031093: AB_10601748, HPA031095: AB_2673734" "unprognostic (2.09e-3)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (1.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.72e-1)" "unprognostic (6.30e-3)" "unprognostic (3.70e-3)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (7.48e-3)" "unprognostic (2.18e-3)" "unprognostic (8.31e-2)" "unprognostic (4.22e-2)" "unprognostic (6.90e-3)" 400.1 92.3 18.2 70.1 26.8 26.6 160.4 19.7 32.1 86.4 20.2 110.9 11.3 97.5 63.0 130.6 104.6 78.9 93.7 16.8 20.7 108.8 144.5 92.7 166.7 22.7 23.8 122.1 200.4 227.0 52.9 28.5 23.5 85.0 37.1 25.6 61.0 49.8 892.7 114.0 135.7 81.8 17.0 105.6 129.0 41.4 22.1 229.4 97.2 925.1 80.3 108.9 109.1 26.2 40.0 17.1 73.1 109.7 759.3 468.5 1.2 21.2 1.0 13.6 31.0 29.7 6.9 195.3 19.5 4.1 11.8 0.6 44.1 93.2 32.0 77.7 41.6 84.0 14.1 41.7 593.0 53.3 8.3 718.3 368.6 23.7 220.5 14.8 80.1 38.8 91.3 77.1 144.3 25.3 222.5 99.6 18.9 8.7 12.3 97.7 19.1 95.4 60.2 23.7 27.7 16.8 17.3 19.8 4.2 15.9 108.4 62.2 178.7 19.3 17.3 2.8 29.7 34.9 42.9 243.5 6.6 102.3 7.6 57.6 105.0 70.0 64.4 92.3 78.0 9.7 90.6 68.5 107.5 12.5 133.4 96.7 85.1 45.2 46.8 32.0 37.2 158.5 18.2 26.8 19.7 32.1 16.8 20.7 22.7 23.8 23.5 17.0 22.1 26.2 180.2 12.8 11.3 23.2 42.9 17.6 59.2 20.1 37.0 1.9 32.0 20.8 131.8 74.4 14.2 5.5 0.0 1.2 102.0 14.3 23.5 0.6 9.8 55.7 76.1 57.9 20.9 102.2 25.9 7.9 0.8 97.5 18.8 79.2 38.5 54.7 117.1 225.6 35.1 0.0 2.8 35.5 34.6 384.2 44.8 22.0 160.9 192.2 7.2 66.5 110.3 4.6 44.3 16.6 26.3 2.9 19.3 218.6 66.4 49.9 157.0 27.4 18.2 22.6 144.7 188.1 106.8 14.9 19.1 37.5 21.3 0.4 128.7 2.8 39.5 22.2 FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 149.1;Endometrial stromal cells: 54.8;Fibroblasts: 67.6;Leydig cells: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 155.0;ASC TERT1: 96.7;fHDF/TERT166: 60.9;HSkMC: 64.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.3 5.4 1.5 3.9 1.6 1.4 11.9 2.6 2.8 23.1 1.5 8.3 2.8 27.8 11.3 5.9 15.1 15.4 12.3 1.6 1.8 5.2 8.3 7.8 2.9 1.6 1.5 50.0 2.8 2.7 5.0 13.0 1.5 9.3 6.2 2.1 5.0 13.3 3.8 4.2 4.4 19.2 1.2 3.0 5.4 4.4 1.5 2.5 6.6 6.5 2.8 11.6 10.2 2.1 0.2 1.9 18.5 27.8 155.0 96.7 1.7 33.3 55.0 5.9 19.0 0.3 1.9 5.4 7.3 60.9 5.5 0.3 7.1 2.8 10.3 4.5 3.9 5.7 7.3 5.5 23.7 3.5 3.8 64.7 1.4 24.0 3.4 44.2 19.8 6.6 2.5 3.4 25.2 0.3 6.1 6.0 3.6 3.5 2.9 7.8 31.9 7.7 8.4 0.6 9.7 32.0 7.0 0.2 6.2 12.7 0.5 6.8 18.2 11.0 6.8 12.8 3.2 6.3 7.2 2.6 19.9 8.7 24.3 0.0 0.4 0.0 1.0 0.7 1.2 1.1 0.9 0.7 2.6 0.7 0.9 1.0 0.0 0.6 0.0 2.1 1.1 0.4 1.5 1.6 2.6 2.8 1.6 1.8 1.6 1.5 1.5 1.2 1.5 2.1 16.2 6.4 4.1 2.9 5.4 7.0 9.3 19.6 7.4 4.2 6.7 13.6 16.1 2.8 5.2 7.3 0.0 7.6 2.7 0.7 1.9 10.9 149.1 3.4 54.8 19.3 1.2 4.2 1.6 8.4 22.4 67.6 4.1 3.5 14.0 19.0 15.7 11.9 5.8 5.0 3.7 5.6 14.2 4.4 13.6 27.1 64.0 3.8 17.8 4.7 1.6 4.2 1.0 7.1 4.2 3.9 0.7 48.5 10.3 3.4 0.4 3.7 2.1 3.6 6.6 31.1 37.7 8.5 5.1 3.7 5.8 5.1 5.5 30.4 3.1 4.1 FKBP8 "FKBP38, FKBPr38" ENSG00000105701 "FKBP prolyl isomerase 8" Q14318 19 18531751-18544077 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 719.1;Late spermatids: 1236.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 93.4;neutrophil: 78.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 93.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025346, HPA045177" Supported Supported "Endoplasmic reticulum,Mitochondria,Cytosol" NA NA 10000 "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "Endoplasmic reticulum, Cytosol" "CAB025346: , HPA045177: AB_2679244" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.24e-4)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (9.22e-2)" "unprognostic (2.54e-2)" "unprognostic (2.26e-1)" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "prognostic favorable (7.76e-4)" "unprognostic (8.51e-2)" "unprognostic (1.61e-1)" "unprognostic (2.97e-1)" "unprognostic (6.89e-2)" "unprognostic (1.12e-2)" "unprognostic (2.32e-1)" 206.9 161.5 426.8 79.8 423.7 272.9 197.3 359.7 645.5 235.3 332.7 311.1 85.5 188.6 59.0 238.3 198.1 85.5 244.3 427.4 395.7 194.8 233.7 187.6 97.9 427.6 405.1 263.6 167.2 109.1 312.3 91.2 406.1 249.4 33.6 51.4 200.0 115.3 202.7 185.9 159.2 62.5 381.7 193.6 189.3 378.4 423.4 86.2 205.9 105.5 52.7 228.3 222.4 437.8 196.3 139.0 106.0 201.7 106.2 165.6 266.8 155.0 163.1 116.5 160.2 133.3 259.1 111.6 245.0 191.7 77.7 104.4 65.0 216.5 31.4 136.6 316.5 105.3 175.4 162.3 183.3 105.5 220.6 217.3 204.8 104.0 65.4 216.1 121.9 213.2 222.4 254.8 102.1 329.1 190.4 313.1 216.3 174.6 200.2 197.8 88.4 387.3 154.9 126.6 117.1 213.2 108.8 87.7 197.5 77.8 104.5 299.4 143.2 143.2 130.3 282.1 120.0 194.6 118.2 130.8 321.5 166.7 130.8 18.1 14.7 93.4 14.2 15.5 13.3 10.2 14.6 16.3 11.1 9.8 11.1 12.6 78.0 8.8 19.0 11.3 15.8 30.1 426.8 423.7 359.7 645.5 427.4 395.7 427.6 405.1 406.1 381.7 423.4 437.8 115.9 9.6 1.1 35.3 115.1 95.3 164.1 118.4 68.3 64.8 110.9 107.4 2.0 115.8 58.0 101.2 14.6 246.4 107.0 287.7 248.4 178.4 412.3 65.6 59.2 92.3 205.9 719.1 32.0 126.9 234.8 126.5 80.5 64.6 52.8 125.0 99.6 66.4 237.3 99.3 33.2 156.8 126.1 184.1 145.0 1236.4 203.8 152.1 202.7 8.4 221.9 149.0 183.4 12.5 32.8 166.9 283.4 165.5 127.2 139.4 339.3 290.4 51.9 56.4 98.6 95.7 129.9 193.5 212.4 96.5 117.9 312.9 145.0 121.7 158.3 158.0 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FUOM "C10orf125, FLJ26016, FucM, FucU" ENSG00000148803 "Fucose mutarotase" A2VDF0 10 133355158-133358025 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 228.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 564.7;Hofbauer cells: 172.0;Proximal enterocytes: 690.7;Proximal tubular cells: 368.1" "Cancer enriched" "Detected in all" 5 "liver cancer: 61.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039207 Approved NA NA 2000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "HPA039207: AB_10795033" "unprognostic (1.15e-2)" "unprognostic (1.16e-1)" "unprognostic (4.48e-2)" "unprognostic (7.19e-2)" "unprognostic (4.82e-1)" "unprognostic (2.66e-2)" "unprognostic (1.66e-2)" "unprognostic (2.45e-1)" "unprognostic (6.25e-2)" "unprognostic (7.56e-2)" "unprognostic (4.50e-2)" "unprognostic (8.67e-2)" "unprognostic (3.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.50e-1)" "unprognostic (4.88e-3)" "unprognostic (1.65e-1)" 12.9 8.8 4.2 11.3 4.4 6.6 13.0 4.0 7.2 7.3 8.2 12.0 52.0 5.5 3.2 8.7 7.9 9.6 17.4 4.2 4.6 46.7 228.3 14.1 16.8 5.3 4.7 7.3 18.3 8.0 6.0 5.2 5.7 7.0 5.4 0.3 28.8 3.6 3.0 7.4 46.8 3.6 4.9 23.7 8.5 5.6 5.1 6.1 6.6 2.6 8.0 7.9 7.7 4.8 23.3 7.2 13.6 28.4 3.8 9.2 24.8 18.3 20.7 6.5 8.1 46.4 12.4 0.0 20.7 13.8 0.0 1.2 4.9 6.3 0.5 8.4 4.9 22.3 10.3 50.7 20.1 25.2 14.8 9.6 0.2 2.6 1.4 3.0 9.2 22.9 22.2 29.7 13.9 23.0 3.9 33.6 9.5 13.5 3.2 21.8 0.4 13.0 7.5 0.0 1.4 11.0 6.7 20.6 25.3 6.8 0.2 38.3 18.7 0.1 18.4 0.0 0.1 15.5 2.7 16.7 5.5 10.2 7.1 0.1 68.9 6.5 16.0 73.2 14.7 36.0 14.0 13.4 57.2 34.5 14.9 13.1 3.3 17.1 15.7 79.0 10.4 28.6 4.2 4.4 4.0 7.2 4.2 4.6 5.3 4.7 5.7 4.9 5.1 4.8 20.4 6.4 10.0 0.0 32.7 12.1 9.2 8.5 6.2 0.1 12.2 25.7 10.9 22.8 11.4 9.2 0.0 10.3 25.1 79.2 31.3 13.6 3.7 3.8 9.7 14.1 3.0 24.4 0.6 12.7 9.0 25.6 8.6 7.7 27.3 15.5 25.0 564.7 172.0 0.0 1.2 49.7 6.1 103.0 55.4 10.3 10.2 68.7 26.6 1.9 85.6 3.5 13.4 0.0 1.0 12.5 119.5 3.8 29.6 17.8 690.7 368.1 4.0 1.1 13.1 11.6 14.9 20.2 23.7 10.0 9.9 6.6 21.5 4.1 61.1 12.1 GALE SDR1E1 ENSG00000117308 UDP-galactose-4-epimerase Q14376 1 23795599-23800781 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" Isomerase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 122.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 276.8;Intestinal goblet cells: 149.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070023 Approved "Golgi apparatus,Cytosol" NA NA 16000 "Cluster 27: Non-specific - Gene expression" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Cytosol" "HPA070023: " "unprognostic (1.65e-1)" "unprognostic (1.78e-1)" "unprognostic (5.25e-2)" "unprognostic (1.41e-2)" "unprognostic (3.03e-3)" "unprognostic (1.17e-2)" "unprognostic (3.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.59e-1)" "unprognostic (2.65e-1)" "unprognostic (1.56e-2)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (7.51e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.68e-4)" "unprognostic (1.41e-2)" 8.9 12.8 12.3 16.0 12.5 6.0 12.8 12.2 17.7 22.3 11.5 58.6 54.6 6.7 12.7 63.1 16.6 31.5 7.1 12.5 12.5 34.0 61.2 20.6 7.5 12.5 12.3 4.6 15.2 15.5 6.7 17.8 12.4 11.0 60.0 6.3 59.7 16.4 4.3 9.7 38.3 10.8 12.6 17.6 122.4 8.7 13.2 8.0 4.7 5.4 15.8 20.9 22.2 12.6 60.3 71.5 27.8 44.5 9.8 13.9 26.9 40.7 53.4 68.6 50.9 65.3 195.4 14.3 54.7 23.5 91.9 65.8 24.5 101.8 51.5 29.4 16.2 40.6 34.4 71.6 102.0 18.4 11.6 30.1 53.4 63.4 156.8 69.2 59.5 30.1 45.9 3.8 49.5 64.5 29.0 19.5 7.8 83.1 67.7 33.6 27.1 18.5 112.7 41.4 10.7 24.1 73.9 66.7 70.6 31.1 47.9 14.5 33.7 52.0 74.9 52.0 50.3 18.5 46.4 18.9 53.0 74.5 27.8 1.7 13.5 3.0 8.5 29.3 8.5 5.4 5.0 6.9 19.0 1.7 5.8 4.1 3.4 37.3 37.1 5.2 9.5 8.8 12.3 12.5 12.2 17.7 12.5 12.5 12.5 12.3 12.4 12.6 13.2 12.6 9.6 12.8 49.3 6.8 7.5 7.6 18.8 110.4 6.2 17.2 26.7 10.9 3.5 37.1 90.6 40.5 16.7 54.1 7.4 131.8 35.2 67.6 21.5 19.9 9.1 14.3 12.1 8.2 9.4 114.8 106.3 14.0 276.8 36.2 10.8 17.4 10.8 38.3 99.3 8.4 10.8 149.5 73.2 5.7 6.8 5.0 4.7 12.5 24.9 5.6 19.4 21.2 7.2 4.5 2.1 92.0 109.0 3.4 9.4 24.9 78.6 89.5 37.0 14.8 0.0 3.7 13.1 14.5 9.7 19.6 4.8 96.3 7.6 99.6 73.8 46.0 GALM ENSG00000143891 "Galactose mutarotase" Q96C23 2 38666081-38741237 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 86.5;kidney: 120.2" "Cell type enhanced" "Detected in many" "Peritubular cells: 97.8;Proximal enterocytes: 161.1;Proximal tubular cells: 222.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 68.3" "Group enriched" "Detected in all" 5 "granulocytes: 39.1;T-cells: 68.3" "Cell line enhanced" "Detected in many" "Hep G2: 62.7;Karpas-707: 71.1;U-266/70: 76.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035472, HPA035473, HPA064835" Enhanced Approved Nucleoplasm NA NA 620000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA035472: AB_10669906, HPA035473: AB_2674642, HPA064835: AB_2732723" "unprognostic (5.02e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (9.20e-2)" "unprognostic (1.88e-2)" "unprognostic (9.99e-3)" "unprognostic (1.63e-2)" "unprognostic (2.80e-3)" "unprognostic (1.87e-1)" "unprognostic (7.17e-2)" "unprognostic (6.65e-2)" "unprognostic (6.45e-2)" "prognostic favorable (9.06e-5)" "unprognostic (1.70e-2)" "unprognostic (1.62e-1)" "unprognostic (4.34e-1)" "prognostic favorable (1.32e-4)" 9.0 86.5 5.2 12.2 5.1 3.8 10.4 6.0 6.1 9.3 8.3 34.7 71.4 8.1 23.0 5.8 35.8 16.5 13.0 4.9 4.8 120.2 72.5 14.3 16.0 5.4 6.1 15.5 15.0 21.3 3.0 7.7 5.4 10.2 33.3 4.4 8.7 20.8 13.1 3.8 52.8 10.4 5.7 6.6 14.9 4.4 7.0 11.0 15.1 12.3 10.2 10.8 6.4 6.0 0.2 27.1 8.1 0.0 27.3 15.4 14.9 3.2 10.3 7.5 12.2 32.4 14.4 10.9 18.9 15.3 14.5 4.3 11.7 0.7 14.5 49.5 19.3 5.9 7.1 62.7 10.0 2.4 0.4 11.1 0.4 17.5 0.0 10.5 8.2 0.0 17.2 71.1 13.9 0.9 23.4 41.0 12.4 59.2 8.6 15.2 0.6 21.3 9.3 45.1 1.5 11.2 0.1 18.9 14.7 10.2 9.0 5.4 3.4 2.5 0.5 18.6 1.0 76.4 54.3 0.3 17.9 7.0 0.3 39.1 4.8 4.2 21.5 3.3 31.8 6.8 33.1 31.2 10.3 4.7 11.7 10.2 11.3 5.5 0.7 0.8 68.3 11.9 5.2 5.1 6.0 6.1 4.9 4.8 5.4 6.1 5.4 5.7 7.0 6.0 9.7 28.9 11.0 13.4 10.0 6.6 6.7 3.4 10.8 3.6 7.8 4.2 23.4 24.3 6.5 69.9 0.0 23.6 19.0 83.2 25.4 12.1 1.4 28.5 11.6 10.0 13.2 8.2 2.3 15.1 31.4 16.1 17.9 10.1 7.0 16.8 14.6 48.1 94.8 3.3 1.4 40.5 4.1 18.6 43.6 1.3 20.2 34.7 17.8 4.7 9.9 38.2 18.6 0.5 1.3 6.8 64.5 97.8 14.7 5.7 161.1 222.1 14.8 6.8 6.6 16.6 10.4 1.0 2.3 3.2 6.0 6.3 44.0 43.3 80.4 5.7 GLCE "HSEPI, KIAA0836" ENSG00000138604 "Glucuronic acid epimerase" O94923 15 69160584-69272217 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 79.0;Microglial cells: 76.8;Oligodendrocytes: 154.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 35.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 1.9;monocytes: 2.3;T-cells: 2.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 119.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040481, HPA048216" Uncertain Approved Mitochondria "Intracellular and membrane" NA NA 240000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA040481: AB_2677004, HPA048216: AB_2680317" "unprognostic (1.30e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-3)" "unprognostic (7.77e-2)" "unprognostic (1.58e-1)" "unprognostic (5.55e-3)" "unprognostic (1.00e-1)" "unprognostic (2.84e-1)" "unprognostic (1.48e-1)" "unprognostic (2.56e-1)" "unprognostic (7.47e-2)" "unprognostic (1.41e-1)" "unprognostic (2.40e-2)" "unprognostic (1.53e-1)" "unprognostic (6.00e-2)" "unprognostic (5.23e-1)" "unprognostic (4.07e-2)" 9.1 12.2 6.7 5.6 7.8 0.9 8.9 35.8 6.2 8.2 8.4 12.8 14.2 6.4 6.9 10.0 5.5 7.5 6.3 6.0 6.7 13.3 16.8 8.4 3.5 5.7 8.5 12.7 4.7 8.7 6.4 13.4 7.2 5.8 14.2 13.2 10.9 5.8 4.1 10.4 11.5 7.0 7.5 4.4 9.1 3.9 8.8 4.9 4.1 4.9 5.1 6.6 4.6 8.0 9.6 8.5 5.6 9.7 18.6 17.6 2.0 17.6 23.2 13.3 25.2 7.1 23.6 5.8 8.5 14.4 16.8 14.0 12.1 11.4 27.1 2.2 13.4 9.7 15.0 7.2 17.9 4.2 19.0 12.1 7.8 16.6 18.6 9.7 119.4 4.3 3.9 6.0 25.4 5.9 2.6 7.4 2.7 9.7 5.9 5.8 22.6 7.3 12.3 10.1 17.9 3.7 18.0 11.0 38.1 3.8 7.9 5.8 41.8 12.7 15.7 14.3 15.8 2.5 3.7 1.3 12.9 7.0 18.8 0.0 2.1 0.0 0.3 1.6 0.5 0.2 0.8 0.4 1.8 0.2 0.5 0.7 0.0 0.2 2.3 1.9 2.0 0.9 6.7 7.8 35.8 6.2 6.0 6.7 5.7 8.5 7.2 7.5 8.8 8.0 16.9 0.0 15.4 4.9 6.2 4.8 10.1 8.3 26.2 10.3 18.8 19.4 8.1 7.2 8.8 11.0 10.4 22.7 12.1 21.3 5.9 13.0 3.9 4.0 5.4 22.6 20.4 9.4 79.0 13.8 12.7 14.0 28.1 4.9 2.5 11.8 16.4 27.2 16.4 8.4 41.5 27.1 10.2 13.3 4.4 5.1 6.2 10.7 8.8 76.8 13.7 13.1 4.1 35.7 154.9 16.9 28.2 17.7 7.1 5.3 32.4 18.3 18.2 16.6 13.1 6.6 9.4 29.8 25.9 27.9 6.5 33.0 5.9 17.1 26.4 13.3 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 331.0;Late spermatids: 1127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" No No 86000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB018655: AB_2112653, CAB040563: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" 196.9 283.2 83.4 74.5 101.9 222.8 129.0 67.7 130.5 95.0 84.8 162.9 113.7 92.4 27.2 197.8 88.8 87.1 407.2 108.5 73.6 196.8 222.6 91.2 66.4 73.5 58.5 97.0 84.2 166.3 147.2 47.5 69.3 94.4 84.3 156.1 105.1 61.0 416.6 120.1 126.5 78.4 34.0 102.2 122.5 95.9 83.2 50.1 100.8 374.6 76.0 147.9 121.5 95.8 572.9 596.1 58.7 433.3 167.5 121.9 134.1 183.4 132.4 206.3 253.7 314.9 169.6 303.5 311.4 177.9 149.1 343.7 337.7 437.0 259.4 461.0 105.1 382.1 252.3 310.8 108.4 517.6 259.3 173.7 136.6 289.0 132.7 273.3 209.3 230.5 210.3 261.8 140.2 319.2 245.5 133.5 158.0 421.3 174.6 242.7 149.1 649.4 254.1 275.4 304.9 185.8 331.9 634.3 131.7 100.5 144.4 161.7 171.9 80.8 185.5 256.7 312.8 535.5 383.7 318.4 287.4 372.3 170.6 188.8 93.2 331.3 80.4 141.2 99.1 59.9 73.7 93.1 101.0 50.5 61.8 72.8 7.4 58.0 180.3 31.6 83.4 123.4 83.4 101.9 67.7 130.5 108.5 73.6 73.5 58.5 69.3 34.0 83.2 95.8 34.2 28.9 40.0 98.9 43.8 25.9 30.1 104.5 42.7 98.8 34.1 27.2 232.5 42.9 51.4 57.0 75.0 44.5 41.6 76.7 115.4 101.7 331.0 35.9 41.2 38.0 63.7 46.7 121.8 66.9 69.2 47.1 109.1 58.0 23.4 36.1 42.8 89.5 89.6 237.2 127.2 75.8 50.8 52.9 40.5 1127.2 37.0 58.1 35.6 17.8 44.4 32.6 23.7 43.7 87.7 77.6 39.4 30.5 77.1 31.5 111.8 103.0 33.1 68.3 19.7 44.3 65.0 7.8 22.3 139.1 32.8 39.3 64.3 74.8 126.9 37.2 GSTZ1 "GSTZ1-1, MAAI, MAI" ENSG00000100577 "Glutathione S-transferase zeta 1" O43708 14 77320996-77331597 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Isomerase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 263.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 373.2;Late spermatids: 398.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 182.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004701 Approved Approved Nucleoplasm,Cytosol NA NA 340000 "Cluster 18: Basophils - Vesicular transport" "Cluster 62: Liver - Hemostasis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol Nucleoplasm "HPA004701: AB_1078990" "prognostic favorable (4.93e-4)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (2.16e-3)" "unprognostic (4.55e-1)" "unprognostic (3.03e-2)" "unprognostic (8.03e-3)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "prognostic favorable (3.73e-4)" "unprognostic (7.90e-2)" "unprognostic (1.73e-1)" "prognostic favorable (1.12e-7)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (4.12e-1)" "unprognostic (4.92e-2)" 13.9 34.7 11.1 9.7 12.5 9.3 23.2 13.2 16.3 12.7 10.5 21.9 22.5 10.8 22.1 26.9 14.9 11.9 14.3 10.5 12.3 24.5 263.1 7.8 13.5 12.6 11.7 6.5 20.1 26.4 13.3 11.2 12.8 21.1 21.7 5.1 24.1 9.6 47.4 22.1 15.6 7.9 12.3 12.1 18.9 57.8 11.9 14.0 19.5 37.3 17.4 11.9 13.8 14.0 18.8 39.0 27.6 19.9 17.1 23.9 45.8 11.4 11.9 21.6 30.9 13.0 45.2 43.5 14.9 13.6 13.4 24.1 18.9 22.5 20.7 23.2 21.0 20.8 13.3 26.9 26.3 7.8 15.8 22.1 24.0 12.4 20.8 12.0 18.6 24.7 17.5 37.0 14.5 182.1 12.2 16.4 8.2 64.1 30.3 20.2 29.5 34.2 32.5 24.0 30.2 26.2 26.0 49.1 35.6 15.5 81.2 11.1 13.8 17.0 52.5 18.9 8.6 28.2 32.7 35.2 41.9 11.3 20.8 13.4 15.5 9.9 2.6 22.2 2.4 8.2 4.6 3.7 20.7 10.4 3.9 3.1 1.6 5.1 20.1 15.0 7.9 7.4 11.1 12.5 13.2 16.3 10.5 12.3 12.6 11.7 12.8 12.3 11.9 14.0 6.1 6.4 9.6 6.5 13.5 13.4 19.8 26.2 15.9 7.3 36.1 34.2 13.0 47.1 19.0 9.2 4.2 91.4 7.5 34.9 46.9 45.0 125.8 19.4 15.6 11.1 28.8 30.3 2.9 68.0 62.5 15.0 33.1 27.0 3.8 25.7 15.4 373.2 44.6 16.8 3.3 45.7 20.3 38.1 10.9 398.1 11.8 19.0 17.8 3.7 30.4 26.4 4.1 2.0 9.2 41.8 37.4 6.0 13.2 19.8 72.9 77.8 15.0 11.9 0.0 12.3 13.2 51.3 29.4 38.0 14.1 76.2 6.7 55.8 50.3 30.3 HPGDS "GSTS, GSTS1, GSTS1-1, H-PGDS, PGD2, PGDS" ENSG00000163106 "Hematopoietic prostaglandin D synthase" O60760 4 94298535-94342876 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 18.7" "Group enriched" "Detected in many" 18 "granulocytes: 1056.2;Hofbauer cells: 631.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 18.1" "Lineage enriched" "Detected in single" 28 "granulocytes: 18.1" "Group enriched" "Detected in some" 8 "HEL: 46.2;HMC-1: 13.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024035 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 250000 "Cluster 46: Basophils - DNA binding" "Cluster 19: Lung - Lung function" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Vesicles, Cytosol" Nucleoplasm "HPA024035: AB_1855743" "unprognostic (5.71e-2)" "unprognostic (5.80e-3)" "unprognostic (1.17e-1)" "unprognostic (5.36e-3)" "unprognostic (2.76e-1)" "unprognostic (2.38e-4)" "unprognostic (1.01e-2)" "unprognostic (4.41e-3)" "unprognostic (1.35e-1)" "unprognostic (7.75e-4)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (5.15e-3)" "unprognostic (4.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.61e-2)" "unprognostic (6.14e-2)" 3.4 1.9 2.2 1.1 2.1 1.1 4.0 2.3 3.1 3.5 2.1 5.1 5.8 2.4 2.3 2.9 1.4 6.9 1.8 2.3 2.3 1.5 0.8 9.4 0.6 2.7 2.6 0.5 0.5 0.8 0.4 18.7 2.9 2.6 5.3 0.1 1.5 1.3 0.5 3.3 5.6 3.3 2.6 0.3 2.8 0.7 3.1 2.0 0.3 1.7 0.9 4.8 1.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.2 0.0 0.0 0.0 3.5 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.1 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 2.2 2.1 2.3 3.1 2.3 2.3 2.7 2.6 2.9 2.6 3.1 3.5 0.3 12.8 44.7 1.0 0.2 4.1 0.8 0.0 0.6 0.0 0.2 0.8 0.3 0.0 3.7 0.0 0.0 3.6 0.7 0.5 0.0 0.5 0.1 0.2 0.0 2.0 7.1 12.2 0.8 0.0 3.0 3.0 3.6 0.0 1056.2 0.0 0.0 0.0 631.9 0.0 0.6 0.0 0.0 11.4 13.1 0.0 0.3 16.3 3.6 32.8 0.1 0.0 0.0 0.0 0.5 0.1 1.2 0.4 2.1 3.9 0.0 0.0 1.5 0.1 0.0 0.6 0.4 0.0 0.1 0.0 5.4 5.5 20.5 0.3 0.9 0.2 HSD3B1 "HSD3B, HSDB3, SDR11E1" ENSG00000203857 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1" P14060 1 119507198-119515054 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 77.7" "Group enriched" "Detected in some" 8 "Extravillous trophoblasts: 140.8;Syncytiotrophoblasts: 502.0" "Cancer enriched" "Detected in single" 4 "urothelial cancer: 1.6" "Region enhanced" "Detected in some" "basal ganglia: 1.0;cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 64.1;SuSa: 26.5" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (1.53e-1)" "unprognostic (7.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "prognostic favorable (4.59e-5)" 0.1 1.2 0.2 0.0 1.0 0.0 1.5 0.0 1.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 77.7 0.0 0.1 0.5 0.0 0.1 0.0 0.1 4.5 8.7 0.5 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.0 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 7.0 0.7 0.8 26.5 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 23.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 140.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 502.0 0.0 0.1 1.0 0.0 HSD3B2 SDR11E2 ENSG00000203859 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2" P26439 1 119414931-119423035 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Steroidogenesis "Isomerase, Multifunctional enzyme, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "adrenal gland: 2174.8" "Group enriched" "Detected in some" 4 "Granulosa cells: 40.6;Proximal enterocytes: 38.8;Theca cells: 68.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.4" "HPA043261, HPA043264, HPA044028" Supported Uncertain "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (3.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.80e-1)" "unprognostic (2.72e-2)" "unprognostic (8.87e-2)" "unprognostic (3.91e-2)" "unprognostic (3.43e-2)" "unprognostic (1.94e-1)" "unprognostic (6.51e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" 0.2 2174.8 0.3 2.1 0.8 0.0 0.1 0.0 0.7 0.2 0.0 7.7 0.0 0.2 0.0 0.2 0.4 0.0 0.3 0.2 0.0 0.9 1.0 0.5 0.0 0.0 0.0 0.9 0.5 0.0 0.1 3.6 0.1 0.4 1.0 0.0 1.0 0.0 0.1 0.2 38.7 0.1 0.0 0.2 0.3 2.9 0.2 0.5 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 1.4 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.7 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 3.5 0.0 0.0 0.0 40.6 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.0 38.8 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 68.9 1.7 0.0 HSPD1 "GroEL, HSP60, SPG13" ENSG00000144381 "Heat shock protein family D (Hsp60) member 1" P10809 2 197486584-197516737 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, Isomerase" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 790.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 1737.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001523, CAB002775, HPA050025, CAB072816" Supported Enhanced Mitochondria NA NA 18000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB002775: , CAB072816: , HPA001523: AB_1079028, HPA050025: AB_2680995" "unprognostic (2.79e-2)" "unprognostic (1.72e-2)" "unprognostic (5.21e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.59e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (2.25e-4)" "unprognostic (3.51e-2)" "unprognostic (9.91e-2)" "unprognostic (8.63e-3)" "unprognostic (3.47e-2)" "unprognostic (7.83e-3)" "unprognostic (5.64e-3)" "unprognostic (1.73e-2)" "unprognostic (1.52e-1)" "unprognostic (2.61e-2)" "unprognostic (4.10e-2)" 179.4 790.6 188.6 128.3 191.6 110.6 168.8 204.9 401.9 96.9 217.8 170.0 158.1 90.8 89.3 124.5 132.6 69.1 145.0 184.3 198.6 374.9 462.6 136.6 149.2 199.6 198.5 167.6 219.0 159.2 116.0 148.6 205.3 104.5 195.1 71.8 93.9 93.6 162.7 83.3 148.7 104.5 195.1 94.6 155.4 57.6 198.6 99.3 138.7 176.7 172.7 144.6 92.3 201.4 559.7 650.1 541.3 496.9 373.6 389.2 786.5 573.2 304.7 686.1 495.6 2219.1 326.2 1724.4 730.0 304.1 834.2 538.4 2232.9 633.2 943.0 417.0 888.2 1209.8 984.8 2562.8 353.2 1331.4 349.1 445.5 717.1 599.5 1053.2 471.4 542.6 919.1 1535.3 606.8 501.7 690.4 853.6 1304.2 1086.4 735.2 1424.9 1000.1 679.7 1235.5 709.5 539.7 716.5 400.8 582.0 608.5 771.0 1116.3 425.0 789.4 242.2 405.8 570.4 532.8 910.0 331.1 861.4 1399.5 485.7 795.3 456.7 12.1 52.3 11.4 36.4 81.8 71.7 63.8 59.6 54.3 84.6 54.0 81.0 70.3 11.0 62.6 72.1 49.4 51.8 70.6 188.6 191.6 204.9 401.9 184.3 198.6 199.6 198.5 205.3 195.1 198.6 201.4 216.4 166.7 172.5 38.8 220.4 246.6 1737.2 247.5 264.0 75.8 216.0 263.1 239.2 195.9 287.9 79.1 256.5 825.7 197.7 213.7 375.6 235.0 6.2 322.2 304.5 233.9 274.6 241.6 31.9 145.9 419.8 356.0 215.6 445.2 299.5 407.1 63.1 312.5 328.0 95.9 47.2 302.2 166.8 88.6 479.3 12.8 130.5 381.9 163.7 30.0 138.5 125.7 68.0 20.6 35.6 171.4 163.2 113.6 322.9 705.9 160.1 797.1 328.6 117.1 85.5 199.0 471.7 88.5 106.0 262.4 207.1 1001.2 467.2 1017.4 512.1 861.5 HYI HT036 ENSG00000178922 "Hydroxypyruvate isomerase (putative)" Q5T013 1 43450989-43453989 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 232.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 29.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 97.7;HUVEC TERT2: 106.7;U-251 MG: 99.2;WM-115: 105.5" "Low region specificity" "Detected in all" HPA040092 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA040092: AB_10795374" "prognostic favorable (9.18e-4)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.96e-4)" "unprognostic (2.68e-2)" "unprognostic (3.86e-1)" "unprognostic (4.40e-2)" "prognostic unfavorable (5.55e-4)" "unprognostic (2.75e-2)" "unprognostic (1.42e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (2.75e-5)" "unprognostic (5.10e-2)" "unprognostic (7.93e-2)" "unprognostic (3.58e-2)" "prognostic favorable (2.72e-5)" 31.7 22.8 28.1 9.3 29.2 12.1 19.3 29.6 36.3 23.4 27.9 21.3 44.1 23.3 15.4 15.0 24.2 18.7 20.8 27.0 31.2 29.5 44.6 23.0 11.3 30.9 28.9 42.1 53.7 25.2 14.6 10.5 30.9 19.8 12.3 4.1 35.3 47.0 20.8 16.2 34.4 13.2 30.0 12.2 23.9 3.9 28.4 8.8 19.1 10.2 9.2 17.4 15.3 32.4 58.7 7.3 2.2 3.5 9.8 15.1 0.2 48.4 35.7 52.6 34.3 24.2 97.7 0.0 4.1 29.7 25.1 10.9 0.0 45.8 21.6 15.2 20.5 10.2 25.0 0.0 58.8 0.0 0.0 9.4 12.4 64.0 0.0 56.3 106.7 0.5 1.2 0.0 34.5 1.2 9.6 8.8 11.1 5.6 15.5 46.0 0.0 0.3 37.5 2.2 27.2 20.3 56.0 30.4 13.2 8.7 9.2 72.0 59.5 3.7 0.0 12.4 99.2 0.0 0.0 0.0 4.1 13.4 105.5 10.6 1.7 3.7 4.2 1.3 5.5 4.3 7.1 3.3 5.8 5.3 6.6 2.0 0.1 7.5 1.8 29.9 0.7 4.0 28.1 29.2 29.6 36.3 27.0 31.2 30.9 28.9 30.9 30.0 28.4 32.4 29.8 19.2 64.4 5.9 16.1 28.0 45.2 22.8 51.8 16.9 41.0 65.3 0.4 65.8 23.0 57.0 10.4 18.6 19.2 56.6 45.0 106.7 1.2 9.9 23.6 23.2 69.5 21.5 1.4 86.1 115.9 45.7 25.5 18.7 43.2 33.5 25.0 59.0 29.8 8.4 1.9 89.1 16.2 8.5 31.0 4.5 31.7 23.5 40.9 1.9 15.8 45.0 8.2 4.5 4.8 109.6 97.0 30.5 41.7 33.7 232.5 146.9 12.4 16.7 26.3 31.3 58.2 1.4 3.0 27.3 22.0 12.0 12.3 49.8 47.6 38.4 IDI1 ENSG00000067064 "Isopentenyl-diphosphate delta isomerase 1" Q13907 10 1039152-1049119 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039169 Approved NA NA 28000 "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA039169: AB_10674280" "unprognostic (1.61e-2)" "unprognostic (2.59e-2)" "unprognostic (4.58e-2)" "unprognostic (1.97e-1)" "unprognostic (5.72e-3)" "unprognostic (1.27e-1)" "unprognostic (1.76e-2)" "unprognostic (1.97e-1)" "unprognostic (3.72e-2)" "unprognostic (3.88e-2)" "unprognostic (2.59e-1)" "unprognostic (2.26e-1)" "prognostic favorable (1.46e-4)" "unprognostic (9.63e-2)" "unprognostic (2.01e-2)" "unprognostic (2.19e-3)" "unprognostic (2.61e-2)" 32.2 93.7 36.9 36.6 38.9 133.9 152.1 44.6 44.2 24.5 36.9 37.3 66.7 17.0 28.5 50.5 16.7 21.9 24.6 39.9 46.8 41.3 160.2 39.9 39.0 49.4 46.9 26.7 31.3 25.9 43.9 23.4 51.1 50.2 34.3 37.5 26.3 13.4 105.9 37.9 34.8 17.7 42.4 44.0 37.2 25.3 44.0 26.3 21.8 44.7 39.8 20.0 30.8 47.0 89.5 33.4 173.4 42.0 71.1 154.1 25.2 36.7 41.5 42.4 88.7 89.6 136.8 80.9 23.6 40.8 101.7 75.8 97.8 177.8 38.3 27.9 93.8 78.2 50.1 103.2 83.9 30.4 37.5 99.3 73.2 119.3 15.6 18.1 33.4 75.0 54.5 111.1 72.2 72.4 59.1 51.9 69.0 74.6 19.5 67.2 82.0 89.5 185.7 79.7 26.6 31.6 46.4 96.5 100.7 53.5 99.3 103.8 33.4 22.7 12.9 66.8 27.2 64.3 64.7 151.3 28.2 89.4 20.4 76.0 15.1 37.6 27.6 28.3 27.5 25.8 21.0 22.7 13.9 26.0 15.3 22.6 41.4 24.2 33.5 14.4 24.8 26.6 36.9 38.9 44.6 44.2 39.9 46.8 49.4 46.9 51.1 42.4 44.0 47.0 119.2 73.7 144.3 53.8 176.2 89.6 80.4 175.7 58.1 77.4 110.0 70.0 79.0 51.5 109.6 40.5 37.5 63.3 233.5 167.5 150.6 62.9 277.8 61.5 28.6 64.6 106.0 31.1 36.2 102.6 53.6 62.8 79.5 108.2 100.7 60.5 67.1 322.8 86.9 63.9 41.0 107.6 156.6 59.1 63.2 101.5 26.4 88.8 133.4 20.6 55.8 130.9 118.4 47.3 65.1 81.9 130.9 29.7 60.2 116.6 70.5 63.5 65.6 70.3 26.3 62.3 73.4 82.5 37.0 79.2 144.6 187.2 154.9 171.1 65.0 121.2 IDI2 IPPI2 ENSG00000148377 "Isopentenyl-diphosphate delta isomerase 2" Q9BXS1 10 1018910-1025859 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "skeletal muscle: 273.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Glandular and luminal cells: 1.1;Horizontal cells: 1.7;Skeletal myocytes: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041254 Uncertain Vesicles NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Vesicles "HPA041254: AB_10794270" "unprognostic (6.69e-3)" "unprognostic (4.05e-2)" "unprognostic (1.64e-1)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.0 1.2 0.0 0.0 273.8 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.1 0.0 11.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.4 0.3 0.0 0.1 0.2 0.2 0.0 0.6 0.3 0.5 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.9 0.5 0.4 0.2 0.0 0.0 0.3 0.0 0.1 0.1 0.0 1.1 0.0 0.1 0.0 0.0 0.2 1.7 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.2 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 ISYNA1 "Ino1, INOS, IPS" ENSG00000105655 "Inositol-3-phosphate synthase 1" Q9NPH2 19 18434388-18438167 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Inositol biosynthesis, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 223.6;testis: 223.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1141.3;Sertoli cells: 315.5;Syncytiotrophoblasts: 1034.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.5;NK-cells: 14.4;T-cells: 8.9" "Cell line enriched" "Detected in many" 4 "BEWO: 492.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007931, HPA008232, CAB020720" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "CAB020720: , HPA007931: AB_2667940, HPA008232: AB_2668018" "unprognostic (1.87e-2)" "unprognostic (1.86e-1)" "unprognostic (2.98e-2)" "unprognostic (3.16e-2)" "unprognostic (3.88e-1)" "unprognostic (1.81e-2)" "unprognostic (2.49e-1)" "unprognostic (3.12e-1)" "unprognostic (1.74e-1)" "unprognostic (2.28e-2)" "unprognostic (2.73e-2)" "unprognostic (5.08e-2)" "prognostic unfavorable (9.23e-4)" "unprognostic (2.23e-2)" "unprognostic (9.26e-2)" "unprognostic (1.19e-2)" "unprognostic (1.50e-1)" 36.0 32.6 15.2 2.8 13.8 5.8 30.5 12.5 19.5 47.3 223.6 14.2 3.6 44.2 4.4 15.2 78.9 3.7 36.1 19.4 24.5 114.4 13.1 22.2 4.4 16.8 18.8 96.0 40.1 12.8 50.7 46.3 14.2 41.4 0.7 0.9 17.7 26.7 13.2 16.2 16.1 2.8 12.7 35.1 11.3 223.8 25.4 3.0 23.7 3.1 1.8 23.5 31.9 11.3 13.9 42.4 98.6 31.0 0.8 0.2 492.7 6.6 1.0 0.6 0.3 24.5 26.1 0.2 33.5 3.2 0.2 36.6 3.0 0.1 0.0 39.8 116.4 52.0 3.1 80.3 10.2 0.6 1.1 9.4 0.4 2.8 0.4 0.4 6.3 1.1 106.0 2.1 0.0 84.1 4.0 3.4 51.7 14.2 33.7 71.2 0.2 24.6 9.5 0.3 30.4 74.3 1.7 9.9 53.1 20.2 68.2 7.1 18.7 0.5 1.1 0.7 1.6 13.9 7.3 3.2 3.0 1.9 17.7 1.0 0.1 0.0 8.1 0.2 6.2 4.5 8.1 6.9 0.8 2.4 6.2 8.9 0.8 14.4 0.1 2.2 6.2 5.0 15.2 13.8 12.5 19.5 19.4 24.5 16.8 18.8 14.2 12.7 25.4 11.3 38.8 3.2 1.1 2.6 9.0 12.0 82.1 74.9 72.8 0.8 26.1 47.0 4.7 20.0 24.0 47.8 2.1 1141.3 8.4 4.1 52.8 39.4 101.3 33.4 10.9 30.5 64.8 21.5 1.0 8.2 114.0 30.2 7.1 14.8 14.0 36.9 25.7 1.1 84.9 0.0 4.3 4.0 28.5 9.0 7.8 230.1 37.3 4.1 23.2 11.2 5.4 8.6 13.4 0.0 0.3 3.4 1.8 50.4 1.8 21.6 0.7 6.1 23.6 0.7 315.5 5.6 163.6 53.7 21.0 10.6 5.7 1034.6 14.9 14.5 6.2 36.8 KATNA1 ENSG00000186625 "Katanin catalytic subunit A1" O75449 6 149594873-149648972 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 416.6;Late spermatids: 194.2;Spermatocytes: 109.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036207 Approved Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Centriolar satellite" Nucleoplasm "HPA036207: AB_10672238" "unprognostic (1.57e-1)" "unprognostic (2.41e-2)" "unprognostic (2.95e-2)" "unprognostic (3.57e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.57e-7)" "unprognostic (9.78e-2)" "unprognostic (8.89e-2)" "unprognostic (7.40e-2)" "unprognostic (2.70e-2)" "unprognostic (4.50e-2)" "unprognostic (3.92e-2)" "unprognostic (2.10e-1)" "unprognostic (3.37e-1)" "unprognostic (1.74e-3)" "unprognostic (8.85e-2)" 12.9 8.2 7.2 10.3 8.4 19.2 12.6 9.6 9.1 13.3 12.3 13.1 8.5 13.3 9.8 12.5 11.8 9.7 11.6 7.0 7.9 13.2 9.0 11.2 14.1 8.2 7.9 19.5 9.5 7.3 7.4 12.7 8.4 9.9 9.9 16.8 9.7 10.9 23.0 12.3 10.0 12.4 7.9 11.8 10.1 45.1 7.8 17.0 11.2 14.3 15.8 12.0 12.7 9.6 22.5 8.3 18.6 42.1 22.9 32.7 28.9 28.7 24.3 29.4 37.2 17.9 11.4 33.7 16.9 28.4 20.4 17.1 34.5 18.5 37.8 30.4 33.8 42.7 17.6 27.9 31.0 60.0 16.4 22.8 22.5 33.3 27.3 27.3 27.8 44.4 46.1 20.7 26.2 32.0 41.2 40.4 19.1 26.2 15.1 30.5 33.3 15.2 21.6 11.6 13.7 20.7 48.9 15.0 22.2 24.3 14.4 61.6 23.7 14.6 23.4 39.2 33.9 20.4 20.3 43.9 19.8 42.7 26.4 39.8 20.4 29.1 25.9 28.5 22.2 27.7 25.2 25.8 26.1 18.3 21.4 20.9 8.7 18.2 25.6 22.3 34.0 20.5 7.2 8.4 9.6 9.1 7.0 7.9 8.2 7.9 8.4 7.9 7.8 9.6 27.6 16.0 11.3 11.8 20.2 29.3 35.7 23.0 12.5 9.1 17.3 26.9 15.5 10.0 15.0 14.7 29.2 23.6 31.4 12.1 17.6 19.5 416.6 23.2 21.6 19.3 6.0 27.4 8.6 12.4 19.4 25.9 11.7 19.3 20.3 23.9 10.0 7.7 17.4 13.5 9.4 9.7 24.4 12.5 19.4 194.2 21.1 17.3 10.6 7.5 22.1 12.2 27.8 13.6 16.3 15.9 12.5 16.6 9.0 19.4 9.7 20.9 23.8 36.1 6.6 40.0 28.5 109.3 58.8 17.7 28.7 25.6 25.6 17.7 12.1 15.4 KATNAL1 MGC2599 ENSG00000102781 "Katanin catalytic subunit A1 like 1" Q9BW62 13 30202630-30307551 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 144.3;Excitatory neurons: 80.6;Oligodendrocytes: 78.5;Spermatocytes: 59.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 63.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046205 Uncertain Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA046205: AB_10965325" "unprognostic (3.34e-1)" "unprognostic (6.44e-3)" "unprognostic (2.08e-2)" "unprognostic (6.91e-2)" "unprognostic (2.53e-1)" "unprognostic (1.52e-1)" "unprognostic (1.57e-2)" "unprognostic (2.84e-2)" "unprognostic (3.43e-1)" "unprognostic (4.68e-3)" "unprognostic (4.54e-2)" "unprognostic (2.17e-2)" "unprognostic (1.84e-3)" "unprognostic (7.41e-2)" "unprognostic (6.42e-2)" "unprognostic (5.12e-2)" "unprognostic (1.83e-3)" 8.7 3.8 7.0 5.0 8.8 6.5 4.7 7.5 8.9 9.7 0.0 8.7 1.4 9.3 2.7 5.8 4.8 3.8 17.9 8.0 8.1 4.0 3.9 4.9 6.5 7.2 6.4 4.2 1.9 2.2 2.9 3.0 7.0 4.5 4.1 7.9 2.2 5.9 5.1 2.6 2.8 15.0 7.5 3.3 2.8 20.8 8.4 9.2 3.0 6.6 7.1 5.0 5.2 11.8 11.7 9.6 16.5 8.8 12.3 26.0 0.4 47.5 15.2 24.9 19.4 1.9 11.6 18.8 5.5 63.7 31.3 3.2 11.8 12.2 37.5 16.3 4.4 13.4 11.2 4.4 6.5 6.7 8.7 10.1 6.0 28.0 6.8 23.3 26.4 10.2 7.3 8.1 30.8 2.4 15.2 6.1 7.1 0.2 6.1 16.8 19.4 1.9 8.8 0.8 6.8 14.3 12.6 2.6 9.0 13.6 4.1 4.1 24.2 21.8 32.7 12.1 19.3 4.2 8.2 25.8 8.7 6.5 32.1 1.5 0.7 2.9 4.4 0.4 2.1 1.9 3.4 4.4 1.9 4.5 0.8 1.8 0.2 7.7 0.9 5.5 5.8 1.2 7.0 8.8 7.5 8.9 8.0 8.1 7.2 6.4 7.0 7.5 8.4 11.8 12.9 9.6 1.8 30.3 7.2 5.9 3.9 4.7 6.2 10.2 4.0 5.6 41.4 2.8 2.3 5.5 27.1 0.4 6.6 0.3 3.9 6.5 144.3 10.3 26.5 9.3 10.2 16.4 80.6 1.5 0.8 12.3 1.5 3.6 10.1 10.3 7.9 10.6 2.9 21.9 34.5 1.0 0.0 2.8 8.9 50.7 9.0 5.9 17.8 21.5 21.9 9.6 13.4 29.1 78.5 5.7 0.0 5.3 6.4 1.9 0.3 8.4 14.7 18.7 6.6 11.9 13.7 59.0 24.6 5.2 5.7 0.3 9.8 19.2 0.7 1.7 KATNAL2 "DKFZP667C165, MGC33211" ENSG00000167216 "Katanin catalytic subunit A1 like 2" Q8IYT4 18 46917492-47102243 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.2;Early spermatids: 91.8;Inhibitory neurons: 41.8;Late spermatids: 71.4;Oligodendrocytes: 38.7;Spermatocytes: 58.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 21.5;Daudi: 28.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040712, HPA042029" Approved Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Intermediate filaments" "HPA040712: AB_2677092, HPA042029: AB_2677807" "unprognostic (3.40e-1)" "unprognostic (7.75e-2)" "unprognostic (9.00e-3)" "unprognostic (9.28e-2)" "unprognostic (1.74e-2)" "unprognostic (6.55e-3)" "unprognostic (6.97e-2)" "unprognostic (1.28e-2)" "unprognostic (3.90e-2)" "unprognostic (5.36e-2)" "unprognostic (9.52e-6)" "unprognostic (1.28e-1)" "prognostic favorable (1.24e-7)" "unprognostic (1.64e-1)" "unprognostic (7.14e-4)" "unprognostic (1.06e-3)" "unprognostic (1.61e-1)" 5.3 3.4 9.6 1.8 11.1 2.7 4.0 14.4 14.7 3.4 23.1 2.6 1.4 2.3 5.5 2.6 7.1 4.4 4.4 9.1 9.2 10.4 6.9 3.3 3.2 10.6 11.5 3.3 2.9 18.0 8.0 1.7 11.2 4.3 2.5 10.8 4.4 2.7 6.1 7.4 2.2 1.8 8.6 3.7 2.2 15.5 10.3 1.9 17.5 2.9 2.1 2.3 3.1 12.9 2.7 5.7 3.5 21.5 7.1 7.9 1.6 2.4 2.1 1.9 2.5 0.2 7.5 28.2 2.2 4.2 2.6 0.9 6.9 0.7 1.6 2.6 3.7 1.3 2.0 0.4 2.8 1.7 2.4 16.5 2.6 3.5 0.9 4.9 0.7 12.8 1.0 2.3 11.5 2.7 1.9 3.7 7.6 4.0 3.9 7.8 1.5 0.1 6.4 0.4 7.6 8.8 2.7 0.5 1.0 11.9 15.5 16.7 1.5 7.1 0.7 2.7 1.7 1.8 1.5 19.7 3.7 18.0 13.4 0.1 0.1 0.1 0.2 0.2 0.2 0.5 0.2 0.1 0.0 0.6 0.3 0.3 0.2 0.1 0.2 0.1 0.0 0.0 9.6 11.1 14.4 14.7 9.1 9.2 10.6 11.5 11.2 8.6 10.3 12.9 3.7 0.0 1.1 84.2 1.0 1.5 3.0 2.9 8.0 9.9 1.6 1.3 2.9 1.5 5.2 3.7 6.2 0.0 0.2 2.5 13.7 0.9 91.8 22.6 6.2 2.5 0.0 1.7 28.2 0.2 0.0 3.1 3.6 1.6 0.0 3.9 2.2 4.2 3.6 11.8 41.8 0.7 2.0 1.9 0.9 71.4 1.5 1.5 3.6 18.7 0.9 2.6 0.0 26.7 38.7 0.2 0.3 2.2 0.4 1.0 0.2 12.1 35.2 2.3 0.0 7.5 1.9 58.7 4.6 2.8 1.1 0.1 0.6 2.6 2.3 1.9 LSS OSC ENSG00000160285 "Lanosterol synthase" P48449 21 46188141-46228824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Isomerase "Cataract, Disease variant, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 132.0;Oligodendrocytes: 158.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 234.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032060, HPA032062, CAB034116" Supported NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB034116: AB_2138611, HPA032060: AB_10671085, HPA032062: AB_2674134" "unprognostic (2.78e-3)" "unprognostic (8.53e-3)" "unprognostic (6.95e-2)" "unprognostic (2.07e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (2.74e-2)" "unprognostic (1.33e-2)" "unprognostic (1.72e-1)" "unprognostic (1.58e-2)" "unprognostic (1.68e-2)" "unprognostic (2.02e-2)" "unprognostic (2.34e-2)" "prognostic unfavorable (6.80e-4)" "unprognostic (1.92e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.07e-4)" 29.3 38.9 20.0 10.8 30.8 5.7 22.3 38.9 33.5 20.8 7.1 22.9 28.5 26.6 12.1 39.7 18.0 9.0 25.1 15.7 26.2 10.7 54.8 24.1 9.4 62.3 40.7 30.3 19.4 12.2 25.9 8.0 65.7 24.0 10.7 6.8 16.1 12.4 29.0 27.6 17.4 12.2 28.4 7.6 23.3 17.5 40.4 12.3 10.2 19.5 8.0 20.2 19.6 58.7 70.4 22.2 70.9 30.6 94.1 90.6 20.3 26.8 186.4 32.1 62.7 73.9 54.4 15.4 22.3 51.7 234.6 32.7 63.2 110.9 12.9 14.9 34.5 37.7 38.6 48.3 85.5 13.7 25.1 89.0 41.4 59.7 25.6 22.2 26.9 72.1 37.4 87.3 27.8 23.8 29.9 19.7 115.4 11.3 20.1 34.9 21.9 92.2 82.8 38.1 41.4 36.7 31.4 24.0 27.5 30.6 38.0 33.7 40.8 37.9 30.2 33.8 21.1 31.8 29.5 30.6 39.7 59.4 16.6 4.6 2.1 2.2 4.0 1.8 2.8 3.1 2.9 4.9 2.4 1.5 2.4 3.6 0.0 1.7 1.5 5.0 1.4 3.6 20.0 30.8 38.9 33.5 15.7 26.2 62.3 40.7 65.7 28.4 40.4 58.7 13.8 12.8 36.8 66.6 7.2 37.0 3.8 30.2 8.0 16.0 15.3 8.0 13.7 14.3 18.7 11.0 4.2 3.7 11.8 10.4 0.0 10.5 6.5 6.6 16.4 10.3 19.7 16.8 21.2 17.2 6.7 19.7 13.3 14.6 3.8 20.6 11.4 132.0 9.7 23.5 24.2 11.6 16.2 7.5 13.7 6.6 21.1 4.9 21.4 21.5 12.0 7.5 5.2 22.1 158.8 14.0 2.7 13.5 6.3 16.2 5.0 4.1 11.0 16.4 0.0 9.8 8.5 20.3 18.1 12.6 54.0 6.3 7.9 18.0 10.9 4.6 MCEE "GLOD2, MCE" ENSG00000124370 "Methylmalonyl-CoA epimerase" Q96PE7 2 71109684-71130239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 92.0;Proximal tubular cells: 77.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035196 Approved Nucleoli "Intracellular and membrane" No No 29000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoli "HPA035196: AB_10601871" "unprognostic (7.65e-2)" "unprognostic (8.20e-2)" "unprognostic (3.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.35e-1)" "prognostic favorable (4.76e-4)" "prognostic favorable (5.78e-4)" "unprognostic (4.86e-3)" "unprognostic (6.48e-2)" "unprognostic (1.08e-1)" "unprognostic (7.43e-3)" "unprognostic (8.59e-2)" "unprognostic (9.40e-3)" "unprognostic (4.90e-2)" "unprognostic (3.55e-1)" "unprognostic (6.51e-2)" "unprognostic (5.38e-2)" 17.8 30.0 8.9 12.3 9.7 9.1 32.7 10.5 12.5 22.1 15.4 20.1 20.1 13.1 30.5 26.3 14.8 14.2 35.9 8.9 9.4 33.7 69.8 13.7 14.7 9.5 9.1 18.5 36.1 35.6 24.1 17.6 9.9 23.9 23.9 12.3 42.8 17.8 36.5 28.4 16.9 12.2 9.7 16.0 23.5 6.0 9.4 13.3 14.1 61.7 15.5 16.5 21.9 11.7 12.1 5.2 10.6 7.6 34.3 46.6 30.2 18.5 23.3 9.2 13.9 14.7 14.8 18.7 5.5 18.5 7.0 12.5 12.4 9.6 9.5 17.1 10.7 12.7 16.3 42.5 19.5 14.5 10.3 31.3 13.5 6.2 12.3 20.5 10.6 14.6 17.1 31.9 9.1 15.5 10.9 16.9 9.6 33.1 14.6 12.8 12.3 35.2 14.8 10.4 11.9 8.8 6.9 40.1 18.1 12.1 31.7 13.4 13.7 10.6 8.3 10.9 7.5 30.7 13.1 20.0 17.5 23.7 9.9 20.3 23.2 27.6 15.4 25.6 21.9 21.6 19.3 15.5 19.9 16.7 17.6 15.0 6.1 16.5 25.3 23.9 35.3 14.6 8.9 9.7 10.5 12.5 8.9 9.4 9.5 9.1 9.9 9.7 9.4 11.7 11.1 25.6 13.4 13.7 12.8 8.5 10.5 18.4 21.6 2.6 37.5 27.3 75.2 25.8 18.2 5.5 2.1 36.2 11.2 14.0 92.0 13.3 1.1 17.2 16.2 9.0 9.0 12.0 13.3 18.4 36.8 23.3 17.3 20.2 0.0 5.2 12.8 73.0 15.1 5.0 14.5 32.5 18.3 10.4 8.7 1.0 29.2 9.4 14.2 14.0 9.1 7.3 5.2 16.1 20.8 9.6 16.2 17.7 42.0 11.0 35.0 77.1 19.4 8.6 26.3 12.7 17.9 3.7 5.1 25.6 20.9 11.4 10.1 16.9 23.0 11.9 MIF "GIF, GLIF" ENSG00000240972 "Macrophage migration inhibitory factor" P14174 22 23894383-23895227 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Isomerase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 2032.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 4974.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003868, CAB005284" Approved Enhanced Nucleoplasm,Cytosol "Secreted to blood" No No 13800000 5000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "CAB005284: AB_648587, HPA003868: AB_1079290" "unprognostic (1.68e-1)" "unprognostic (7.79e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" "unprognostic (1.33e-1)" "unprognostic (1.36e-2)" "unprognostic (9.48e-2)" "unprognostic (1.22e-3)" "unprognostic (2.17e-2)" "unprognostic (1.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.28e-2)" "unprognostic (2.19e-2)" "unprognostic (1.20e-1)" "unprognostic (1.55e-1)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" 233.3 467.9 195.8 119.5 200.0 146.0 223.3 209.3 450.0 235.0 204.3 194.3 98.9 205.3 49.8 514.2 219.4 20.9 290.8 245.2 289.7 530.3 484.6 208.2 61.5 225.2 224.7 223.7 255.7 127.8 368.0 100.4 217.2 318.7 35.2 23.8 233.6 132.8 99.3 302.5 171.7 43.4 250.8 204.5 230.7 113.5 204.2 65.0 274.0 19.5 46.2 255.8 316.7 369.4 1698.3 605.3 122.2 499.0 58.9 111.3 590.7 581.2 154.7 298.9 382.1 526.4 364.4 761.3 499.8 83.1 115.2 788.1 155.0 546.8 51.5 642.2 4974.4 286.2 534.6 1126.5 225.3 1077.2 758.6 230.9 354.9 173.8 103.5 248.8 241.3 589.4 466.9 540.1 122.2 1476.0 827.0 2345.5 532.8 488.6 2365.8 1040.4 127.9 2398.8 294.7 179.6 1080.9 1290.4 380.3 531.9 1374.7 37.6 671.2 442.6 424.7 232.5 1227.9 127.3 9.9 1647.2 732.5 1020.9 967.5 484.6 477.9 484.2 543.5 443.5 872.4 579.5 1250.8 1527.9 1221.7 983.3 796.9 1378.9 1040.4 928.4 166.8 1158.9 383.3 977.1 1258.3 1803.3 195.8 200.0 209.3 450.0 245.2 289.7 225.2 224.7 217.2 250.8 204.2 369.4 161.2 157.0 199.4 21.5 433.4 672.2 295.5 1134.8 1027.2 28.3 856.0 778.2 0.3 479.0 489.1 693.4 2.1 462.7 171.3 317.9 1649.4 859.0 190.5 733.7 485.3 248.5 348.9 455.7 17.1 377.7 885.0 336.2 606.5 844.3 180.3 192.2 261.6 885.2 278.8 21.9 24.1 432.5 697.8 207.7 505.2 153.9 336.1 232.6 773.7 19.7 217.0 59.5 155.5 17.6 52.8 649.9 360.4 302.8 1337.1 269.8 476.8 2032.7 404.6 33.2 138.1 338.1 349.7 21.3 124.2 1511.3 758.8 686.0 386.3 227.6 473.0 256.1 MMUT "MCM, MUT" ENSG00000146085 "Methylmalonyl-CoA mutase" P22033 6 49430360-49463253 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 199.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 62.5;Cytotrophoblasts: 26.5;Extravillous trophoblasts: 13.3;Hofbauer cells: 12.4;Syncytiotrophoblasts: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035971, HPA035972" Enhanced Approved Mitochondria,Cytosol NA NA 150000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol Mitochondria "HPA035971: AB_10696648, HPA035972: AB_2674895" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.17e-2)" "unprognostic (3.72e-2)" "unprognostic (3.18e-3)" "unprognostic (1.20e-1)" "unprognostic (1.16e-2)" "unprognostic (1.16e-2)" "unprognostic (3.62e-2)" "unprognostic (1.89e-2)" "unprognostic (6.57e-2)" "unprognostic (9.89e-2)" "prognostic favorable (8.71e-13)" "unprognostic (5.38e-2)" "unprognostic (3.78e-1)" "unprognostic (6.01e-3)" "unprognostic (1.91e-1)" 19.8 23.3 12.1 11.5 13.2 8.6 18.4 14.2 16.2 14.0 19.3 22.6 27.1 15.2 15.6 17.9 13.9 14.2 31.0 12.1 13.5 50.6 199.0 12.5 11.8 13.0 12.7 24.2 24.6 31.1 11.7 13.2 13.2 20.8 21.5 17.2 18.7 15.8 23.6 15.0 20.1 14.9 14.1 9.4 20.1 14.6 13.3 12.2 19.2 36.1 11.2 13.0 11.9 16.3 23.9 8.3 24.6 28.8 47.8 45.1 13.6 20.9 27.3 21.6 31.7 9.7 12.1 21.9 16.3 22.4 32.6 13.3 27.6 14.8 30.2 18.9 20.0 11.7 17.5 25.4 34.8 15.1 10.8 27.4 21.6 22.0 25.4 19.3 21.1 23.4 21.6 25.6 25.7 15.0 17.9 14.9 10.5 25.0 6.0 15.8 30.8 30.7 24.9 22.6 22.7 15.8 23.0 16.3 35.7 25.6 14.2 23.9 15.4 20.0 14.6 27.4 28.7 10.0 12.2 18.8 28.1 17.6 17.9 16.0 6.5 11.4 6.4 8.8 8.2 7.6 7.7 8.1 7.8 6.9 9.6 7.2 3.8 12.5 14.7 5.5 10.9 5.8 12.1 13.2 14.2 16.2 12.1 13.5 13.0 12.7 13.2 14.1 13.3 16.3 6.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.5 0.0 0.0 0.0 0.0 26.5 2.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 13.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 33.4 0.6 0.0 0.0 0.0 MPI ENSG00000178802 "Mannose phosphate isomerase" P34949 15 74890005-74902219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007200 Approved Approved "Plasma membrane,Cytosol" NA NA 350000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "HPA007200: AB_1854079" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.65e-3)" "unprognostic (7.34e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (1.79e-1)" "unprognostic (2.76e-1)" "unprognostic (3.20e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (3.34e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.09e-1)" "unprognostic (6.58e-2)" 18.9 50.5 45.4 16.7 47.3 11.7 20.1 52.2 49.2 23.9 41.1 31.8 45.6 23.6 35.3 27.7 27.8 16.0 44.8 46.6 47.9 31.2 39.1 14.9 20.9 55.5 50.1 30.6 31.8 31.1 22.9 16.2 56.2 27.5 31.4 33.6 23.7 22.9 52.2 16.5 33.0 22.5 45.7 23.0 20.9 26.2 50.0 23.2 23.2 70.9 24.2 24.2 19.5 47.1 27.2 36.9 29.8 34.0 66.7 32.2 26.0 22.8 37.2 38.4 53.4 36.7 35.0 38.3 48.6 33.6 30.6 65.9 60.0 66.7 36.2 29.4 74.9 68.8 35.3 39.9 47.5 32.0 19.4 43.1 16.9 36.2 64.4 58.1 52.9 45.2 23.4 30.7 50.1 23.2 34.6 14.2 16.4 40.9 31.0 35.0 28.0 94.9 45.5 30.4 55.7 24.4 26.7 47.5 28.7 43.5 65.3 21.9 24.1 22.9 19.4 17.3 22.6 75.0 48.4 25.1 47.9 45.8 17.1 2.3 16.2 5.7 28.2 17.0 37.0 27.4 38.3 32.6 23.0 31.9 56.0 40.8 2.7 43.1 15.5 19.1 53.1 29.0 45.4 47.3 52.2 49.2 46.6 47.9 55.5 50.1 56.2 45.7 50.0 47.1 5.6 6.4 15.0 7.8 10.8 1.9 7.6 16.4 5.2 23.4 9.2 10.7 54.1 7.2 10.9 14.7 4.2 31.8 9.1 28.3 15.6 19.6 18.9 5.6 9.2 9.6 10.8 4.2 4.9 8.8 11.4 10.9 6.1 8.5 15.2 13.3 6.1 18.8 23.9 35.3 6.1 19.0 8.2 7.2 2.2 31.3 11.1 6.6 3.6 3.7 9.7 20.7 12.3 2.0 6.9 12.2 33.2 8.6 11.8 7.2 70.1 31.4 7.8 16.7 6.6 8.2 10.1 34.5 9.0 9.1 2.7 16.3 11.1 21.0 16.4 6.2 MRI1 "MGC3207, MRDI, mtnA, Ypr118w" ENSG00000037757 "Methylthioribose-1-phosphate isomerase 1" Q9BV20 19 13764522-13774282 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042744, CAB045988" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No 880000 "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "CAB045988: AB_2145566, HPA042744: AB_2678141" "unprognostic (1.16e-1)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.14e-2)" "unprognostic (1.05e-1)" "unprognostic (3.24e-1)" "unprognostic (1.57e-2)" "unprognostic (4.27e-3)" "unprognostic (1.61e-1)" "unprognostic (8.98e-2)" "unprognostic (1.50e-3)" "unprognostic (1.75e-2)" "unprognostic (1.18e-2)" "unprognostic (1.67e-1)" "unprognostic (1.77e-1)" "unprognostic (1.28e-1)" 15.8 19.2 7.9 9.0 8.2 9.5 18.5 9.3 8.5 24.8 7.0 17.3 9.6 21.6 4.1 20.5 21.8 5.3 12.9 7.6 7.5 22.3 23.8 15.8 10.5 8.9 7.7 24.4 19.6 7.8 18.0 11.9 8.7 19.3 6.4 5.3 20.5 8.8 11.6 26.0 21.1 5.2 7.1 23.1 18.3 3.6 8.4 7.8 23.0 4.4 8.7 17.6 22.4 10.9 14.7 9.3 5.5 13.1 6.1 9.5 13.0 17.9 9.3 13.8 12.4 9.9 11.5 7.9 6.5 6.6 7.3 25.4 24.5 15.5 10.8 12.6 39.3 6.6 18.5 12.0 4.7 20.3 14.8 9.9 9.4 7.1 6.0 14.3 13.7 7.9 11.6 0.6 7.4 18.7 21.9 14.3 9.1 6.0 27.2 20.5 7.6 17.4 8.1 11.4 10.4 9.9 6.6 13.9 14.5 7.7 11.1 8.2 8.2 8.2 7.6 29.3 8.8 11.0 11.3 2.4 6.8 22.5 9.7 3.4 1.8 0.7 1.7 1.7 1.8 1.5 1.7 2.2 1.4 1.6 1.3 1.1 1.6 1.8 1.1 2.7 1.5 1.3 7.9 8.2 9.3 8.5 7.6 7.5 8.9 7.7 8.7 7.1 8.4 10.9 9.2 9.6 19.8 15.0 10.8 11.1 8.9 10.8 6.8 4.3 9.0 8.4 0.9 8.6 13.4 16.5 8.4 13.2 17.2 8.1 5.9 9.2 0.7 11.5 14.4 13.8 9.1 13.3 22.3 12.7 8.7 12.3 14.3 14.2 13.3 9.9 12.8 10.0 7.2 1.7 19.6 9.3 6.1 7.2 8.4 1.7 17.4 7.4 1.8 9.4 10.5 5.0 17.5 18.1 15.2 6.8 11.0 15.1 13.3 4.7 16.5 10.5 19.2 9.3 26.3 10.8 13.3 0.3 4.5 13.3 11.4 5.3 16.0 22.2 9.8 6.8 NAXE "AIBP, APOA1BP, MGC119143, MGC119144, MGC119145, YJEFN1" ENSG00000163382 "NAD(P)HX epimerase" Q8NCW5 1 156591756-156609507 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Lipid transport, Transport" Isomerase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 136.7;Distal tubular cells: 201.5;Ductal cells: 112.8;Exocrine glandular cells: 100.1;Proximal tubular cells: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043766, HPA048164" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA043766: AB_2678660, HPA048164: AB_2680294" "unprognostic (1.27e-1)" "unprognostic (2.34e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.38e-2)" "unprognostic (5.32e-2)" "unprognostic (2.46e-3)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (3.08e-3)" "unprognostic (3.23e-2)" "unprognostic (3.14e-2)" "unprognostic (2.15e-2)" "unprognostic (8.05e-2)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-1)" 47.1 74.8 61.0 20.9 63.7 22.2 47.9 66.1 69.6 56.8 71.1 62.9 45.5 68.8 88.7 58.0 59.5 26.5 111.1 60.9 64.3 83.8 86.5 43.6 27.0 62.7 64.8 46.5 69.7 104.7 70.0 23.7 61.8 62.5 41.6 17.4 53.9 48.3 71.8 55.8 48.3 39.7 64.7 43.2 67.5 40.8 63.5 30.6 59.8 68.2 34.3 55.0 47.8 70.5 114.2 155.4 43.9 84.4 64.0 43.8 55.5 29.5 62.3 69.5 72.6 130.6 76.8 62.4 113.4 52.5 55.9 111.1 49.4 99.0 47.5 81.2 98.5 58.1 76.2 86.1 75.1 60.0 60.9 44.2 123.7 87.9 81.9 53.4 95.4 104.7 54.7 70.1 71.6 209.6 83.3 98.0 43.1 158.1 118.2 87.7 40.2 212.6 93.0 93.6 114.7 102.9 90.4 172.4 141.6 66.4 178.3 117.5 51.1 45.1 64.8 64.6 70.6 180.1 110.3 53.0 63.1 37.0 70.4 25.4 96.3 52.9 121.2 111.3 121.3 236.2 109.4 124.3 89.1 186.5 122.8 114.9 11.4 141.3 89.1 225.7 110.1 186.6 61.0 63.7 66.1 69.6 60.9 64.3 62.7 64.8 61.8 64.7 63.5 70.5 29.5 41.7 32.9 0.0 14.8 0.0 0.0 0.0 0.0 0.0 87.5 96.0 0.0 0.0 23.5 68.0 0.0 136.7 28.7 0.0 201.5 112.8 0.0 27.3 29.9 18.4 0.0 0.0 0.0 100.1 43.1 27.2 0.0 32.0 5.1 53.5 0.0 0.0 92.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 40.8 0.0 0.0 0.0 0.0 91.0 0.0 0.0 6.2 0.0 0.0 219.6 11.7 0.0 0.0 0.0 24.5 0.0 0.0 0.0 0.0 81.3 13.4 48.1 0.0 0.0 NKTR p104 ENSG00000114857 "Natural killer cell triggering receptor" P30414 3 42600655-42648735 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022120, HPA051576" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 42: Non-specific - Transcription" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane, Cytosol" "HPA022120: AB_1854513, HPA051576: AB_2681540" "unprognostic (2.73e-3)" "unprognostic (3.11e-1)" "unprognostic (2.33e-1)" "unprognostic (2.06e-1)" "unprognostic (5.27e-3)" "prognostic favorable (1.26e-4)" "unprognostic (4.62e-2)" "unprognostic (5.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.01e-4)" "prognostic unfavorable (5.02e-4)" "unprognostic (3.82e-1)" "unprognostic (4.57e-1)" "unprognostic (1.40e-1)" "prognostic favorable (1.05e-5)" 17.4 19.2 16.4 17.6 18.7 46.5 19.3 22.3 17.1 28.4 17.9 17.7 13.2 18.4 22.4 17.0 23.0 11.4 17.8 15.0 20.3 18.2 21.1 23.9 22.1 20.5 16.4 29.0 22.1 10.6 36.5 11.1 17.6 23.2 13.4 41.3 17.5 10.5 19.5 32.6 25.4 10.7 14.0 36.7 16.3 18.0 18.2 15.4 25.4 10.4 20.0 18.3 22.6 27.8 15.1 7.7 32.3 15.6 16.6 19.3 14.9 22.8 6.8 9.9 12.9 14.7 13.3 25.9 10.7 9.1 9.0 12.6 16.1 8.4 19.2 11.0 13.1 31.4 30.5 24.6 7.3 25.4 19.9 9.6 12.2 18.4 10.5 19.1 17.4 7.1 30.3 20.2 18.6 6.9 17.8 35.5 23.1 7.6 12.3 17.3 12.0 10.5 15.7 12.7 9.4 8.5 24.1 11.1 4.8 16.3 17.5 17.8 28.0 18.0 13.1 21.4 23.2 17.2 21.7 17.7 10.1 30.0 11.3 7.8 3.6 7.5 5.7 4.6 5.3 5.5 5.6 4.9 2.9 5.3 5.6 4.9 5.3 7.0 6.8 5.1 5.3 2.3 16.4 18.7 22.3 17.1 15.0 20.3 20.5 16.4 17.6 14.0 18.2 27.8 221.8 109.0 141.4 169.4 129.5 59.0 60.3 57.8 66.0 200.0 76.3 69.8 68.7 65.8 73.2 88.3 246.0 72.5 156.0 60.3 17.6 47.3 23.9 114.4 125.5 166.2 71.8 76.6 143.5 38.8 51.1 83.3 86.6 132.4 96.8 210.0 110.7 58.6 45.9 132.9 170.0 70.2 61.1 53.8 70.2 21.8 167.7 78.9 51.6 194.9 97.4 101.9 163.7 180.0 267.2 47.6 59.2 134.3 131.3 77.5 106.8 17.0 53.3 279.9 92.1 103.5 88.9 246.2 186.1 42.4 57.3 31.3 164.4 104.5 75.0 54.2 P4HB "DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB" ENSG00000185624 "Prolyl 4-hydroxylase subunit beta" P07237 17 81843159-81860856 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chaperone, Isomerase" "Craniosynostosis, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1856.8;pancreas: 2446.9" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 1077.9;Extravillous trophoblasts: 1349.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012463, HPA018884" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No No 110000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB012463: , HPA018884: AB_1854896" "unprognostic (9.47e-3)" "unprognostic (1.09e-2)" "unprognostic (2.99e-2)" "unprognostic (7.14e-3)" "unprognostic (7.75e-3)" "unprognostic (1.05e-2)" "unprognostic (1.30e-1)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (4.73e-3)" "unprognostic (1.43e-1)" "unprognostic (3.93e-2)" "prognostic unfavorable (2.30e-11)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (4.99e-3)" "unprognostic (3.19e-3)" 266.5 507.8 34.6 209.8 35.7 517.1 225.5 39.1 35.7 272.0 59.6 258.4 640.2 206.5 133.0 618.7 183.4 202.0 318.4 31.7 50.2 270.7 1856.8 301.3 104.0 48.9 37.1 187.8 2446.9 144.3 330.0 334.3 40.8 335.8 173.6 23.3 948.1 184.2 328.5 370.4 554.7 179.8 39.8 428.6 539.2 68.8 58.7 89.3 244.8 150.8 137.9 233.7 322.9 43.7 690.3 580.7 236.8 687.5 813.4 726.7 593.6 1038.5 1081.1 741.9 934.5 550.4 576.9 264.4 501.8 1120.2 407.5 464.1 248.8 647.4 254.1 145.8 320.5 355.2 362.9 953.6 1010.8 1146.4 613.4 618.8 494.8 478.2 596.7 843.0 1250.1 182.1 273.6 978.2 559.5 566.4 260.5 723.2 157.7 791.0 463.8 261.8 342.5 614.0 453.2 492.8 248.7 301.1 586.1 1693.1 808.1 289.6 855.3 1601.2 644.1 980.5 503.1 574.3 586.6 743.5 407.9 204.8 1372.0 591.3 825.4 198.3 268.1 163.0 202.6 154.4 209.8 83.9 138.9 165.7 174.7 68.1 74.9 114.6 72.9 157.0 115.3 311.5 105.6 372.4 34.6 35.7 39.1 35.7 31.7 50.2 48.9 37.1 40.8 39.8 58.7 43.7 122.3 102.5 162.1 23.2 151.4 120.1 163.6 371.0 140.6 59.2 283.0 170.8 24.1 247.4 211.7 112.2 33.3 790.2 208.9 420.7 41.1 671.9 43.5 78.4 196.8 153.9 199.9 140.9 15.3 1077.9 1349.1 272.5 388.9 209.1 99.1 210.4 190.2 840.7 435.9 62.2 16.2 610.9 189.2 186.9 125.5 64.9 141.4 180.3 136.9 20.6 263.3 122.7 230.7 13.6 19.6 575.2 465.6 112.1 664.3 310.6 914.2 105.0 91.3 54.3 157.8 103.4 226.7 83.4 94.1 302.3 144.6 1001.2 138.8 378.4 475.4 220.8 PDIA2 "PDA2, PDI, PDIP, PDIR" ENSG00000185615 "Protein disulfide isomerase family A member 2" Q13087 16 283164-287215 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "pancreas: 2509.7" "Cell type enriched" "Detected in some" 4 "Exocrine glandular cells: 294.9" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 28.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.9;HEK 293: 7.9;Hep G2: 6.7;Karpas-707: 2.9;MCF7: 4.6;SH-SY5Y: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051692, HPA053492" Enhanced "Intracellular and membrane" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" "HPA051692: AB_2681575, HPA053492: AB_2682169" "unprognostic (3.46e-2)" "unprognostic (7.98e-3)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" "unprognostic (2.17e-2)" "unprognostic (6.27e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-1)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (2.90e-2)" "unprognostic (1.58e-14)" "unprognostic (3.06e-2)" "unprognostic (1.66e-1)" "unprognostic (8.75e-2)" "unprognostic (2.87e-2)" 2.8 0.6 64.4 0.4 70.1 0.6 0.8 80.5 96.0 0.6 61.2 2.7 23.9 0.3 0.9 0.9 0.7 0.1 4.4 64.2 66.7 0.6 0.6 0.7 0.2 76.6 67.1 1.5 2509.7 0.0 7.6 2.5 73.2 1.0 0.3 2.4 1.0 0.1 0.6 0.4 7.1 0.0 69.9 0.3 191.7 1.0 68.7 0.0 0.4 0.0 0.5 0.5 0.6 88.5 0.0 1.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.1 0.1 3.9 0.1 0.5 0.0 7.9 0.0 0.3 6.7 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.1 0.0 0.3 2.9 0.1 4.6 0.1 0.4 0.2 1.6 0.0 0.1 0.0 0.9 0.0 0.0 1.6 3.7 0.0 0.1 0.0 0.5 1.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.4 70.1 80.5 96.0 64.2 66.7 76.6 67.1 73.2 69.9 68.7 88.5 0.0 0.0 0.5 1.6 1.9 0.5 0.0 0.0 0.0 4.2 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.1 0.3 0.1 0.0 0.0 12.4 294.9 1.3 5.5 65.7 0.1 0.0 0.1 0.0 0.0 0.4 0.0 14.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.9 1.6 0.6 0.0 2.0 22.2 25.5 1.4 0.4 0.2 0.0 3.9 1.1 0.0 0.5 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.5 0.0 0.0 1.4 0.0 PDIA3 "ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC" ENSG00000167004 "Protein disulfide isomerase family A member 3" P30101 15 43746410-43773278 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1048.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002645, HPA003230, CAB011199, CAB015181, CAB075744" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" NA NA 200000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB011199: AB_609902, CAB015181: AB_2160857, CAB075744: AB_2665750, HPA002645: AB_1079031, HPA003230: AB_1079030" "unprognostic (9.20e-2)" "unprognostic (1.21e-3)" "unprognostic (1.34e-1)" "prognostic favorable (2.05e-4)" "unprognostic (2.40e-2)" "prognostic unfavorable (8.95e-5)" "unprognostic (1.67e-1)" "unprognostic (8.60e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.11e-8)" "unprognostic (1.82e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (6.63e-2)" 17.0 16.6 7.5 16.5 8.0 27.1 15.6 9.2 7.6 24.7 13.9 20.6 23.6 16.4 44.7 18.9 15.4 13.5 17.3 7.7 9.8 15.3 34.5 16.8 18.7 9.3 8.2 16.5 36.0 22.6 16.2 23.8 9.1 25.2 22.5 8.4 21.6 19.1 7.6 17.3 21.4 17.0 9.0 12.5 20.4 10.8 9.3 9.6 56.0 4.1 12.3 15.6 15.2 9.8 29.4 11.9 24.6 55.1 48.9 51.9 70.8 58.6 62.1 46.0 56.7 33.6 32.1 33.8 37.4 72.9 30.8 47.8 31.8 61.5 39.7 24.3 44.7 47.2 17.6 30.9 80.1 26.0 33.8 33.6 49.8 35.0 58.5 54.0 81.3 11.1 27.7 17.4 45.5 11.1 9.1 30.4 24.4 48.5 44.0 17.9 36.7 26.2 39.3 26.0 22.9 25.4 48.7 49.0 19.4 25.0 33.1 28.1 50.9 37.7 18.9 29.7 29.1 7.1 8.6 33.9 48.1 41.2 28.8 11.6 8.8 13.3 12.1 9.2 12.8 5.4 6.8 9.5 8.3 6.1 6.0 7.1 2.4 12.7 9.9 17.6 5.8 15.8 7.5 8.0 9.2 7.6 7.7 9.8 9.3 8.2 9.1 9.0 9.3 9.8 224.9 192.3 183.9 31.6 177.8 192.2 313.7 665.2 114.4 56.5 137.9 95.5 58.3 124.4 427.7 167.3 41.7 655.2 319.6 228.7 70.5 401.2 24.3 178.8 300.3 223.7 186.1 95.3 29.2 390.4 807.8 350.7 261.0 328.5 261.6 255.1 233.1 342.2 426.0 70.7 38.3 523.1 231.9 157.3 292.2 26.7 253.5 246.5 243.7 36.5 258.0 128.3 279.1 29.7 38.8 279.9 196.8 276.8 341.1 286.5 234.3 129.1 245.6 61.9 124.9 138.4 389.7 186.4 147.6 138.9 148.5 1048.8 237.8 390.8 335.4 291.7 PDIA4 "ERP70, ERP72" ENSG00000155660 "Protein disulfide isomerase family A member 4" P13667 7 149003062-149028662 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 386.7;Hepatocytes: 595.4;Plasma cells: 556.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006139, HPA006140, CAB017368" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 15000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB017368: AB_10621725, HPA006139: AB_1848256, HPA006140: AB_1848257" "unprognostic (1.98e-1)" "unprognostic (1.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (9.69e-4)" "unprognostic (1.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.11e-2)" "unprognostic (5.11e-2)" "unprognostic (3.24e-3)" "unprognostic (6.08e-3)" "unprognostic (3.20e-2)" "prognostic unfavorable (5.20e-9)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" 50.3 30.0 22.8 91.5 27.5 35.7 38.2 31.1 24.1 92.8 33.6 84.8 74.1 58.6 163.5 38.9 81.6 53.5 40.4 22.1 31.2 49.5 241.7 48.5 59.0 35.3 29.3 47.3 112.6 26.4 44.6 92.0 34.2 69.3 85.5 8.4 56.1 47.4 9.3 30.0 66.3 71.9 29.6 63.6 95.6 30.8 33.8 46.7 234.1 10.1 72.4 65.6 33.3 49.8 251.3 236.0 249.8 703.3 223.2 158.2 358.2 343.5 230.5 194.8 314.5 196.6 661.5 179.4 748.2 287.0 532.2 160.1 170.6 329.1 168.9 129.0 99.0 86.6 62.7 436.6 298.4 198.5 233.9 156.4 145.1 213.6 169.8 251.7 401.0 90.6 143.6 476.1 173.4 276.4 190.9 226.0 371.1 510.9 134.0 123.6 192.5 440.5 228.2 194.9 79.1 207.6 313.0 223.7 124.1 295.7 127.4 151.9 220.6 152.1 84.5 372.0 247.5 357.5 173.7 125.5 354.2 231.1 528.9 74.4 80.5 51.0 130.4 85.6 135.4 99.1 83.7 100.8 77.6 58.2 77.4 82.7 11.0 91.9 91.4 251.8 68.7 160.6 22.8 27.5 31.1 24.1 22.1 31.2 35.3 29.3 34.2 29.6 33.8 49.8 43.3 28.9 36.2 6.8 87.9 34.7 88.0 142.5 29.0 4.2 50.8 31.5 31.0 95.8 92.4 42.3 4.2 177.8 86.9 135.4 15.6 129.0 3.1 91.1 93.1 57.0 61.6 41.2 3.2 91.0 386.7 102.8 119.8 107.1 57.8 72.0 81.4 595.4 147.9 0.0 5.7 282.9 61.1 84.7 49.6 5.5 59.0 55.3 87.2 9.4 51.8 15.6 68.0 4.5 11.9 94.5 88.6 42.9 556.7 108.1 71.3 66.3 114.8 6.7 32.9 35.2 66.0 47.6 86.1 29.2 28.6 230.4 46.7 52.4 155.6 72.4 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 4700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 17.9 23.6 0.3 15.2 0.3 17.9 13.8 0.2 1.4 14.5 2.7 20.1 13.9 12.4 30.2 6.1 14.0 19.6 9.9 0.6 0.8 14.5 80.2 17.7 11.1 0.5 0.6 11.5 26.6 10.7 12.7 47.4 0.4 32.3 25.0 4.2 13.7 7.9 4.2 8.8 12.8 17.0 0.3 10.1 33.4 15.3 0.9 4.5 30.8 4.3 12.0 17.9 9.5 0.7 24.0 14.6 17.7 21.5 80.3 71.9 95.0 44.9 74.5 24.5 66.9 47.8 21.6 0.0 57.6 69.9 15.7 12.5 7.8 27.4 25.7 1.1 8.8 10.4 3.9 56.7 33.2 26.5 1.4 62.3 40.2 16.6 34.5 26.1 84.0 10.1 13.6 60.4 16.9 29.6 7.2 31.3 13.1 54.5 15.6 6.7 13.0 67.5 20.7 13.9 19.3 11.4 22.0 24.0 40.4 28.7 21.4 32.3 47.2 6.2 19.5 29.4 12.3 18.1 5.0 10.8 20.2 21.0 21.5 0.0 9.3 0.3 1.4 2.4 2.3 3.5 1.0 0.8 5.5 1.1 0.6 0.6 0.2 0.5 0.5 12.8 0.0 2.3 0.3 0.3 0.2 1.4 0.6 0.8 0.5 0.6 0.4 0.3 0.9 0.7 17.2 19.2 30.7 2.6 5.6 5.0 6.0 6.4 3.4 13.1 6.9 4.7 2.7 35.8 11.3 5.5 39.6 41.8 3.1 5.4 0.0 32.2 1.6 5.4 13.1 24.3 8.4 5.5 9.6 28.6 133.6 20.7 30.5 21.1 3.8 7.3 37.5 50.1 12.1 0.0 7.1 36.9 0.0 7.8 5.5 2.0 24.2 4.4 8.8 5.6 5.0 2.3 0.0 1.0 2.5 11.9 7.6 22.2 40.1 18.1 3.5 5.3 6.4 28.4 13.1 3.6 17.6 1.3 1.5 3.4 4.1 50.2 3.1 23.3 15.1 4.5 PDIA6 "ERp5, P5, TXNDC7" ENSG00000143870 "Protein disulfide isomerase family A member 6" Q15084 2 10783391-10837977 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1202.1;Plasma cells: 883.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034347, HPA034652, HPA034653" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 15000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Cytosol" "CAB034347: AB_2299360, HPA034652: AB_2674263, HPA034653: AB_10601982" "unprognostic (8.16e-2)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.20e-4)" "prognostic unfavorable (3.63e-5)" "unprognostic (3.17e-2)" "unprognostic (1.02e-2)" "unprognostic (5.25e-3)" "unprognostic (6.03e-3)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (6.59e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-2)" "unprognostic (3.69e-3)" 118.3 112.3 54.5 155.8 64.6 140.8 124.9 57.1 66.7 178.8 71.2 156.0 122.4 131.6 418.5 98.2 133.5 96.7 113.4 55.9 60.8 130.3 260.5 103.8 118.1 61.1 55.4 99.8 252.1 149.7 74.0 171.3 60.7 127.4 171.6 48.0 184.1 135.5 59.3 64.3 121.5 155.5 60.9 107.4 155.4 55.1 62.6 86.6 363.3 59.4 153.7 130.9 75.7 66.4 287.0 304.6 425.7 672.6 535.6 459.4 753.4 677.8 625.9 348.3 465.1 435.1 548.5 460.9 464.7 668.9 674.1 228.0 324.1 568.3 371.1 363.2 253.4 374.2 228.4 713.2 577.5 387.9 268.9 334.2 428.4 338.1 603.3 642.1 798.0 171.8 328.0 963.6 348.7 338.8 150.5 400.8 356.6 923.4 236.4 355.7 433.0 846.4 498.3 339.9 272.0 543.2 267.6 387.0 396.2 547.8 136.8 648.5 395.0 324.4 409.8 296.3 399.1 900.0 596.6 297.1 438.5 479.6 464.8 276.1 200.0 95.5 198.4 210.9 219.0 197.6 154.2 187.6 215.0 161.0 74.3 125.1 35.0 241.6 161.4 268.9 174.4 319.2 54.5 64.6 57.1 66.7 55.9 60.8 61.1 55.4 60.7 60.9 62.6 66.4 217.1 57.7 124.2 17.6 193.9 103.0 294.2 552.8 61.5 69.1 121.1 91.7 35.9 148.7 264.6 196.8 29.2 456.3 164.6 125.8 43.0 338.6 8.2 146.5 382.9 176.2 157.7 89.2 47.4 240.6 1202.1 228.2 138.1 255.0 131.3 210.6 211.3 355.6 413.1 42.1 30.5 276.3 170.9 155.7 149.8 16.2 121.2 145.9 199.3 15.0 132.1 106.5 142.2 32.6 25.3 175.4 131.2 135.1 883.2 385.4 99.9 149.6 145.8 60.1 85.5 96.9 225.3 98.5 117.9 95.4 102.6 554.1 125.7 254.3 248.3 265.3 PGAM1 "PGAM-B, PGAMA" ENSG00000171314 "Phosphoglycerate mutase 1" P18669 10 97426191-97433444 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 791.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042528, HPA060483" Approved Supported Nucleoplasm NA NA 120000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "HPA042528: AB_2678039, HPA060483: AB_2684292" "prognostic unfavorable (2.04e-4)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.64e-1)" "unprognostic (5.64e-2)" "unprognostic (1.16e-1)" "unprognostic (9.47e-3)" "unprognostic (7.60e-3)" "unprognostic (1.74e-3)" "unprognostic (3.22e-1)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "unprognostic (2.48e-2)" "unprognostic (1.48e-1)" "unprognostic (5.74e-2)" "unprognostic (4.94e-2)" "unprognostic (1.19e-1)" "unprognostic (2.61e-3)" 149.0 294.7 228.7 153.6 249.7 180.0 122.1 252.9 265.0 184.3 275.1 162.9 151.5 153.7 98.6 436.7 117.2 106.6 275.7 256.1 266.0 167.6 182.5 121.7 165.7 241.7 242.7 133.3 81.8 191.3 150.8 156.6 280.9 107.3 141.9 420.7 164.7 156.5 56.5 206.9 141.4 177.9 228.3 139.6 133.2 87.5 278.8 124.9 86.9 70.2 229.7 186.6 233.3 224.7 1160.6 538.9 364.0 697.9 336.7 307.7 494.1 722.4 938.4 830.2 1148.3 589.4 335.4 609.1 482.7 619.2 333.4 706.8 639.8 1051.4 998.1 567.2 611.7 393.6 386.4 667.5 248.4 570.0 503.9 303.2 422.5 552.7 408.7 1118.9 610.8 447.2 262.0 334.0 884.8 478.3 514.7 697.8 559.0 331.8 637.8 384.2 333.6 484.0 646.0 431.1 79.1 370.1 388.6 229.2 381.2 564.9 625.0 472.9 463.8 441.5 385.2 394.8 844.0 499.0 593.1 556.1 1023.3 937.5 209.3 242.5 433.5 572.7 217.0 366.6 192.3 134.8 183.8 216.9 309.7 114.7 117.5 164.9 312.6 149.4 422.7 110.5 265.6 580.2 228.7 249.7 252.9 265.0 256.1 266.0 241.7 242.7 280.9 228.3 278.8 224.7 92.9 44.8 44.4 23.8 122.2 187.0 173.1 394.2 124.1 403.5 77.8 76.7 22.9 85.8 140.8 106.7 77.2 495.8 122.3 233.9 358.1 321.8 15.1 50.2 113.7 145.9 48.1 71.1 29.4 205.8 791.9 146.0 68.8 72.0 103.4 109.5 96.8 193.7 395.1 387.0 35.7 116.7 152.5 170.0 129.1 27.0 149.5 174.6 131.6 16.9 376.9 404.4 174.0 14.1 19.9 295.7 132.9 234.3 254.9 175.2 283.0 274.8 72.1 300.5 203.8 73.1 199.9 38.0 114.7 253.3 204.7 372.6 138.0 257.8 176.4 269.6 PGAM2 PGAM-M ENSG00000164708 "Phosphoglycerate mutase 2" P15259 7 44062727-44065567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "heart muscle: 1132.9;skeletal muscle: 4350.5;tongue: 1754.5" "Group enriched" "Detected in many" 6 "Early spermatids: 539.1;Late spermatids: 1891.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "SCLC-21H: 65.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA043801, HPA050314, HPA060173" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA 38000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Nucleoli, Cytosol" "HPA043801: , HPA050314: AB_2732558, HPA060173: AB_2684215" 4.1 3.7 32.9 0.1 37.7 0.1 2.9 40.9 43.1 2.8 28.9 2.1 2.0 1.8 0.7 58.9 2.3 2.4 1132.9 29.3 45.0 10.6 1.8 2.0 0.3 33.8 39.8 2.0 2.1 4.0 13.5 0.1 46.0 16.5 0.3 4.3 33.6 0.6 4350.5 1.8 1.3 0.5 30.8 1.2 1.7 193.9 46.8 23.9 5.1 1754.5 0.5 0.7 1.9 39.8 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 65.8 7.0 0.0 0.3 0.4 0.1 0.7 0.0 0.0 0.0 0.2 0.1 0.0 1.0 0.7 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 32.9 37.7 40.9 43.1 29.3 45.0 33.8 39.8 46.0 30.8 46.8 39.8 0.7 0.0 0.0 6.8 1.2 1.1 0.3 0.1 0.6 15.6 0.2 0.6 0.0 0.0 0.3 0.0 10.4 0.0 0.0 0.2 80.3 0.1 539.1 4.0 0.4 1.5 22.9 0.0 0.1 0.5 0.0 0.6 1.5 5.6 0.0 0.4 0.0 0.3 0.0 0.0 0.7 0.4 4.1 0.3 1.4 1891.7 7.8 1.5 1.8 1.9 0.0 5.6 0.0 1.0 0.5 0.3 1.2 6.0 1.4 0.2 0.4 9.2 0.1 4.6 26.3 78.3 18.6 187.6 7.0 0.2 0.6 0.0 0.6 0.1 0.2 0.5 PGAM4 "dJ1000K24.1, PGAM-B, PGAM1, PGAM3" ENSG00000226784 "Phosphoglycerate mutase family member 4" Q8N0Y7 X 77967949-77969638 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 2.3;Basal respiratory cells: 1.6;Langerhans cells: 1.5;Melanocytes: 3.6;Suprabasal keratinocytes: 2.4" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A-431: 1.3" "HPA042528, HPA060483" Uncertain Uncertain Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA042528: AB_2678039, HPA060483: AB_2684292" "unprognostic (3.10e-2)" "unprognostic (2.41e-2)" "unprognostic (5.25e-2)" "unprognostic (3.18e-2)" "unprognostic (4.37e-2)" "unprognostic (4.21e-2)" "unprognostic (7.71e-2)" "unprognostic (1.89e-2)" "unprognostic (1.78e-1)" "unprognostic (7.52e-3)" "unprognostic (3.19e-2)" "unprognostic (1.14e-1)" "unprognostic (4.20e-2)" "unprognostic (1.20e-1)" "unprognostic (4.15e-2)" "unprognostic (1.10e-1)" "unprognostic (2.76e-3)" 0.1 0.2 0.1 0.2 0.1 0.4 0.1 0.0 0.4 0.1 0.0 0.1 0.2 0.1 0.0 0.3 0.1 0.0 0.2 0.3 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.4 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.1 1.3 0.4 0.1 0.4 0.0 0.0 0.6 0.2 0.0 0.2 0.2 0.0 0.1 0.1 0.4 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.3 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.8 1.0 0.3 0.0 0.1 0.3 0.1 0.4 0.1 0.1 0.0 0.6 0.2 0.1 0.5 0.2 0.2 0.2 0.0 0.2 0.4 0.4 1.0 0.5 0.4 0.3 1.0 0.7 0.1 0.5 1.0 1.5 0.5 1.0 0.4 0.3 0.5 0.5 0.8 0.3 0.3 0.5 0.6 0.4 1.1 0.2 0.9 1.7 0.1 0.1 0.0 0.4 0.3 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 1.6 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.4 0.1 0.1 0.0 0.0 0.0 PGM1 ENSG00000079739 "Phosphoglucomutase 1" P36871 1 63593411-63660245 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Congenital disorder of glycosylation, Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 1559.1;tongue: 788.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 238.4;Extravillous trophoblasts: 185.9;Hepatocytes: 214.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004666, HPA024190, HPA024637, HPA046329" Enhanced Supported Cytosol NA NA 21000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "CAB004666: AB_425590, HPA024190: AB_1855266, HPA024637: AB_1855267, HPA046329: AB_2679625" "unprognostic (2.50e-1)" "unprognostic (2.26e-3)" "unprognostic (1.74e-2)" "unprognostic (5.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-2)" "unprognostic (1.86e-3)" "unprognostic (2.42e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.74e-5)" "unprognostic (7.07e-2)" "unprognostic (1.55e-2)" "unprognostic (6.58e-3)" "unprognostic (1.37e-1)" "unprognostic (2.46e-1)" "unprognostic (9.74e-3)" 113.7 70.8 31.6 20.7 34.7 21.5 57.4 34.3 38.4 33.9 53.1 58.9 60.8 22.9 19.2 49.3 17.0 30.3 178.9 31.4 34.0 52.2 279.8 42.6 14.7 44.7 34.1 51.0 112.2 65.3 31.8 26.9 32.7 46.6 49.9 22.6 41.8 49.7 1559.1 30.6 55.1 41.4 31.9 14.7 30.6 11.1 36.5 14.3 27.5 788.0 19.4 38.4 22.1 30.2 113.4 47.0 17.3 57.0 111.0 81.4 138.6 45.7 61.8 48.9 79.0 38.8 51.3 35.8 93.2 71.2 107.4 26.5 24.0 96.3 55.9 44.0 32.1 75.3 72.6 40.3 91.6 66.8 4.3 103.4 60.7 57.1 88.5 129.8 29.6 36.3 0.1 46.3 78.8 6.9 19.6 36.7 78.3 3.4 73.9 26.8 80.0 11.8 70.0 35.3 10.4 66.7 100.0 103.0 157.4 78.6 32.4 25.2 3.1 71.6 36.0 64.0 39.4 29.1 45.5 57.8 117.0 58.0 31.5 46.0 33.2 49.2 40.5 22.4 32.7 22.4 23.5 31.0 48.4 11.8 21.0 24.7 38.7 43.9 21.2 13.9 20.4 35.4 31.6 34.7 34.3 38.4 31.4 34.0 44.7 34.1 32.7 31.9 36.5 30.2 8.4 93.0 29.4 48.3 16.9 17.8 29.0 58.8 47.8 9.2 33.8 21.8 139.2 48.6 24.2 16.5 10.4 76.6 14.2 81.8 88.0 55.9 32.0 8.2 12.1 12.7 13.1 5.7 17.9 238.4 185.9 37.0 27.0 13.5 5.1 134.3 15.0 214.4 24.6 0.0 26.3 47.5 20.3 17.0 10.8 8.5 22.1 13.5 26.6 4.7 32.8 75.8 29.9 32.2 9.8 70.5 31.6 38.0 40.4 29.2 90.2 74.8 17.0 11.4 13.1 53.4 25.5 5.6 10.1 57.3 18.2 58.8 19.0 20.2 81.5 19.0 PGM2 FLJ10983 ENSG00000169299 "Phosphoglucomutase 2" Q96G03 4 37826660-37862937 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Muller glia cells: 334.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040676 Uncertain Approved "Intermediate filaments" NA NA 1700000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" "Intermediate filaments" "HPA040676: AB_2677076" "unprognostic (3.11e-2)" "unprognostic (1.01e-2)" "prognostic favorable (2.14e-5)" "unprognostic (2.29e-1)" "unprognostic (3.94e-1)" "unprognostic (5.44e-2)" "unprognostic (1.70e-2)" "unprognostic (2.09e-3)" "unprognostic (5.32e-2)" "unprognostic (7.02e-2)" "unprognostic (5.37e-2)" "unprognostic (2.22e-2)" "unprognostic (6.72e-3)" "unprognostic (3.21e-2)" "unprognostic (1.88e-1)" "unprognostic (9.97e-2)" "unprognostic (1.02e-1)" 8.2 11.2 3.2 9.5 3.2 10.1 8.8 4.6 4.5 10.9 4.5 9.8 7.6 10.1 4.9 36.6 7.9 11.3 5.6 4.9 3.1 8.0 14.8 6.9 10.0 3.4 3.0 6.9 4.4 8.4 3.0 11.7 3.6 7.8 9.0 18.2 7.7 5.2 1.2 17.5 7.8 13.7 3.5 8.3 6.1 5.3 3.1 10.2 9.7 1.9 22.7 18.9 16.4 3.7 27.4 9.5 14.6 16.6 10.2 12.4 19.8 32.6 18.9 27.8 26.4 18.0 19.2 38.0 15.5 17.8 34.9 13.8 36.0 32.0 65.1 23.0 21.0 40.1 15.2 12.3 23.2 44.2 26.5 17.0 36.0 22.0 18.6 16.2 41.6 31.2 53.6 6.2 24.3 15.6 49.8 49.6 17.3 19.2 15.5 35.8 23.1 14.8 15.7 52.3 31.8 10.8 17.5 23.3 12.0 19.5 21.5 45.4 37.0 19.7 24.9 27.3 67.1 14.0 38.4 40.3 10.9 56.2 32.9 19.8 27.5 67.2 9.8 22.4 11.5 9.4 8.0 11.1 31.9 5.5 7.7 9.8 33.6 28.1 18.2 7.1 14.9 17.0 3.2 3.2 4.6 4.5 4.9 3.1 3.4 3.0 3.6 3.5 3.1 3.7 16.9 0.0 8.2 5.2 13.8 14.7 14.3 32.9 17.6 7.8 12.6 6.9 4.5 14.3 23.1 3.7 0.0 31.9 11.9 10.6 5.9 16.0 0.9 9.0 12.7 22.9 7.2 8.0 8.3 11.8 37.8 10.3 5.6 14.7 12.7 56.4 42.5 9.7 37.9 6.7 5.6 9.2 4.1 24.4 15.2 2.0 8.4 24.5 5.4 4.7 46.1 334.1 13.4 8.0 0.9 14.5 6.7 9.8 10.5 17.7 6.9 10.4 9.8 16.0 13.1 5.8 23.8 0.6 2.1 42.5 32.1 79.8 14.7 19.8 12.9 20.4 PGM3 "AGM1, DKFZP434B187, PAGM" ENSG00000013375 "Phosphoglucomutase 3" O95394 6 83161150-83193936 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004998, HPA029759, HPA029760" Enhanced Approved Nucleoplasm,Cytosol NA NA 220000 "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Cytosol" "CAB004998: AB_425591, HPA029759: AB_10600305, HPA029760: AB_10601109" "prognostic unfavorable (8.78e-4)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.45e-2)" "unprognostic (3.03e-2)" "unprognostic (1.51e-2)" "unprognostic (4.04e-2)" "unprognostic (1.09e-3)" "unprognostic (6.72e-3)" "unprognostic (3.11e-1)" "prognostic favorable (9.96e-4)" "unprognostic (4.00e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.39e-7)" "unprognostic (2.21e-1)" "unprognostic (7.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.22e-3)" 23.6 21.0 12.0 18.1 12.9 9.3 18.0 20.2 15.2 24.4 19.6 18.0 15.8 17.1 34.5 12.3 13.4 24.6 14.3 9.7 10.5 13.6 38.3 16.8 11.2 10.9 10.2 22.7 46.1 13.3 28.2 47.5 13.1 51.0 23.4 26.8 35.8 20.3 6.7 10.9 18.2 18.5 6.6 11.5 24.9 32.3 11.1 8.2 25.6 8.6 15.2 19.0 12.3 15.9 35.1 23.4 41.8 51.0 68.9 72.9 48.9 118.1 82.9 55.2 83.3 60.1 16.1 18.3 24.7 112.3 53.0 20.1 38.4 49.5 104.6 14.6 37.8 22.7 41.9 105.0 77.6 22.6 11.2 46.2 40.1 96.6 120.0 55.5 64.6 12.1 74.9 19.6 61.0 39.1 3.7 14.7 18.8 31.8 31.6 16.2 92.5 11.3 42.0 36.0 16.9 26.3 34.8 28.5 20.9 61.8 27.0 25.5 94.2 38.3 21.2 74.9 60.5 36.5 16.1 13.0 29.7 17.7 58.4 10.8 4.1 2.7 2.6 3.5 3.9 4.6 2.8 3.4 3.6 2.5 4.5 4.7 1.8 3.5 4.5 4.2 2.1 2.3 12.0 12.9 20.2 15.2 9.7 10.5 10.9 10.2 13.1 6.6 11.1 15.9 14.3 28.9 27.7 14.4 13.0 15.8 29.2 28.5 5.7 16.4 19.9 15.0 6.8 15.7 36.1 11.0 10.4 32.4 12.7 15.9 7.9 31.7 67.7 17.0 35.1 13.8 16.1 6.9 25.1 49.6 71.1 46.1 23.9 36.4 5.1 25.4 14.3 32.6 17.6 8.4 29.4 35.5 18.3 6.0 8.7 20.9 33.5 8.6 10.6 15.9 10.1 25.9 2.1 41.2 36.8 37.9 19.7 18.4 44.1 56.5 16.1 23.2 22.2 21.1 6.6 22.1 26.6 75.5 34.2 11.6 15.6 64.4 10.1 12.2 17.6 25.6 PIN1 dod ENSG00000127445 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 1" Q13526 19 9835257-9849689 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 782.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004528, CAB009326, HPA068650, HPA070887" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 120000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "CAB004528: AB_628132, CAB009326: AB_2237080, HPA068650: AB_2686014, HPA070887: " "unprognostic (2.54e-1)" "unprognostic (6.14e-3)" "unprognostic (6.50e-2)" "unprognostic (4.36e-2)" "unprognostic (1.71e-2)" "unprognostic (6.50e-3)" "unprognostic (1.90e-1)" "unprognostic (2.86e-2)" "unprognostic (2.67e-1)" "unprognostic (7.23e-3)" "prognostic favorable (3.25e-4)" "unprognostic (9.43e-2)" "prognostic favorable (7.80e-5)" "unprognostic (2.20e-2)" "unprognostic (2.56e-1)" "unprognostic (3.13e-2)" "unprognostic (1.21e-2)" 55.3 90.1 130.7 31.2 140.6 48.1 52.3 132.5 201.4 59.4 99.9 83.2 36.4 61.7 7.2 59.5 63.7 13.0 105.5 149.6 141.4 70.1 63.2 49.0 26.4 152.6 134.4 54.6 43.5 28.2 69.2 20.5 156.7 74.7 9.3 20.6 39.6 22.0 90.4 54.3 49.0 16.7 113.9 53.8 61.1 98.4 133.8 42.3 44.8 33.4 12.4 67.4 52.4 132.7 116.8 104.5 75.4 70.8 25.8 22.9 45.1 85.3 35.7 60.9 58.3 97.5 36.1 72.0 132.0 31.7 63.8 58.4 52.2 49.6 19.3 153.9 223.5 187.0 137.2 85.5 41.9 88.0 105.0 31.5 33.5 39.5 18.7 45.7 49.9 124.1 86.1 105.4 37.3 81.0 133.7 338.6 72.8 47.8 156.8 120.6 79.4 121.2 44.5 56.4 95.1 112.4 82.0 40.5 96.6 30.8 51.9 104.3 87.3 85.6 68.3 133.6 139.1 135.0 137.0 97.1 90.9 111.3 107.2 280.9 181.0 397.6 170.1 202.0 159.8 165.5 165.5 171.8 171.4 176.5 130.5 146.0 114.0 192.2 195.8 316.9 245.5 214.7 130.7 140.6 132.5 201.4 149.6 141.4 152.6 134.4 156.7 113.9 133.8 132.7 73.8 28.9 20.5 11.1 48.8 48.3 65.7 153.9 23.3 77.3 56.1 62.0 79.6 44.3 67.4 62.5 12.5 119.4 81.3 82.3 164.4 101.5 270.5 75.9 57.6 65.6 99.9 78.9 41.3 108.6 98.1 66.5 38.7 40.6 63.5 83.6 56.4 45.8 140.7 60.6 39.2 70.6 160.7 54.7 75.2 782.4 90.1 60.6 124.5 20.6 131.6 87.9 138.0 11.6 24.3 113.7 81.2 129.8 74.3 68.9 97.0 143.8 104.5 76.0 65.7 52.3 98.6 186.7 94.7 54.0 65.9 55.0 77.8 81.8 69.2 58.5 PIN4 "EPVH, PAR14, PAR17" ENSG00000102309 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 4" Q9Y237 X 72181353-72302926 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054483, HPA064504" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA054483: AB_2682503, HPA064504: AB_2685274" "unprognostic (2.47e-1)" "unprognostic (6.97e-3)" "unprognostic (1.65e-1)" "unprognostic (3.77e-2)" "unprognostic (8.42e-2)" "unprognostic (1.30e-2)" "unprognostic (1.14e-2)" "prognostic favorable (6.37e-4)" "unprognostic (1.56e-1)" "unprognostic (2.13e-2)" "unprognostic (2.49e-1)" "unprognostic (9.54e-2)" "unprognostic (2.09e-3)" "unprognostic (1.92e-1)" "prognostic favorable (2.58e-4)" "unprognostic (3.34e-3)" "prognostic favorable (2.66e-4)" 14.1 14.8 23.5 10.4 24.0 8.7 16.9 25.2 36.3 15.2 24.0 16.2 11.5 14.7 21.5 14.4 12.9 7.3 19.0 23.6 24.8 19.7 28.6 10.6 10.5 24.4 24.2 16.1 13.1 20.4 13.9 11.8 24.2 15.6 12.7 18.3 16.1 10.1 19.4 10.6 12.7 10.8 24.0 13.9 15.8 5.7 23.8 17.5 16.5 20.4 11.1 13.2 14.9 25.4 36.8 41.2 42.5 29.9 28.1 23.4 23.1 24.6 26.8 28.7 29.1 20.8 26.4 11.2 68.6 25.2 39.2 25.8 38.6 43.0 35.6 26.9 83.3 18.8 51.1 55.3 14.9 29.9 14.8 15.7 22.5 32.0 11.1 32.4 29.1 32.5 32.1 46.6 20.4 43.4 25.3 49.9 30.3 42.4 36.7 25.8 34.7 32.3 37.1 24.7 27.0 48.1 28.5 13.3 27.0 32.0 20.3 25.9 30.7 13.4 19.9 36.8 17.7 15.4 18.5 17.9 38.5 28.3 14.7 42.7 37.1 40.6 41.8 41.1 41.7 49.2 43.7 40.3 38.0 45.6 44.1 44.8 15.7 41.1 39.4 44.6 58.1 39.6 23.5 24.0 25.2 36.3 23.6 24.8 24.4 24.2 24.2 24.0 23.8 25.4 68.3 67.3 48.2 14.0 44.4 43.2 63.3 167.9 36.5 26.7 67.2 94.5 84.9 78.6 89.4 119.5 8.4 162.8 44.5 99.2 181.9 125.0 13.5 78.6 66.7 71.5 92.7 71.7 17.8 117.9 89.0 59.9 45.3 56.6 57.6 46.3 92.4 288.5 110.3 28.6 17.8 93.7 128.1 72.9 44.9 9.3 74.6 50.7 60.5 7.5 69.6 90.7 80.3 16.6 27.3 136.3 114.9 81.3 38.7 51.5 162.0 296.1 95.9 42.9 85.5 65.9 94.6 19.6 42.6 51.3 46.9 120.7 44.8 53.9 88.5 54.8 PMM1 Sec53 ENSG00000100417 "Phosphomannomutase 1" Q92871 22 41576900-41589871 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030712, HPA074950" Uncertain Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA030712: AB_10669600, HPA074950: " "unprognostic (2.66e-1)" "prognostic favorable (5.92e-4)" "unprognostic (3.25e-2)" "prognostic favorable (6.09e-6)" "unprognostic (1.25e-1)" "unprognostic (2.85e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "unprognostic (1.78e-1)" "prognostic favorable (2.05e-4)" "unprognostic (6.56e-3)" "unprognostic (5.76e-3)" "unprognostic (2.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.40e-2)" "unprognostic (2.70e-1)" 47.0 51.7 49.0 12.0 50.4 26.2 39.0 47.0 65.0 34.4 41.2 33.6 37.7 26.9 19.2 73.7 34.7 18.8 26.5 49.5 52.1 59.4 64.2 33.8 17.5 46.9 47.2 48.1 45.0 15.4 19.5 14.2 51.2 26.5 20.3 13.6 23.3 20.2 16.2 33.2 33.8 19.9 47.8 13.7 65.7 32.6 49.8 14.3 13.8 11.4 16.8 31.7 28.0 49.7 16.0 29.0 19.6 42.5 54.3 84.0 23.0 61.7 69.8 56.0 61.0 23.0 15.3 14.9 20.3 74.4 40.0 23.4 25.8 40.0 31.1 31.2 38.6 3.8 34.8 49.2 85.8 22.6 23.8 70.4 38.2 58.3 24.2 61.9 9.3 23.8 16.9 51.9 76.5 42.0 17.1 32.5 6.2 75.1 38.2 13.1 20.7 30.7 24.0 17.1 5.8 11.2 50.5 18.1 75.2 15.2 20.3 24.4 7.5 63.2 34.3 59.4 32.8 33.2 34.0 24.3 70.3 18.8 38.7 21.0 22.0 44.8 27.7 18.5 22.3 17.8 27.6 22.8 23.2 20.5 29.4 21.1 28.8 13.4 22.9 9.2 49.4 18.8 49.0 50.4 47.0 65.0 49.5 52.1 46.9 47.2 51.2 47.8 49.8 49.7 7.8 35.3 106.4 16.3 15.0 14.8 10.2 22.5 20.5 16.7 22.8 29.3 12.4 82.9 25.8 35.0 6.2 57.1 10.0 104.8 107.6 31.8 17.1 77.7 34.2 6.9 48.7 19.3 14.9 11.0 91.1 33.3 36.2 51.4 3.8 60.9 8.9 83.5 34.5 28.6 10.9 58.1 14.2 14.4 13.5 15.3 28.0 16.3 44.4 3.7 21.9 67.1 16.5 4.0 7.1 10.8 117.0 30.5 17.7 8.5 176.1 138.5 34.8 22.6 39.5 18.9 36.9 72.6 10.9 23.1 14.1 65.3 21.0 37.9 55.3 8.2 PMM2 "CDG1, CDG1a, CDGS, PMI, PMI1" ENSG00000140650 "Phosphomannomutase 2" O15305 16 8788823-8849325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "basophil: 210.5" "Lineage enriched" "Detected in all" 13 "granulocytes: 210.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040852, HPA063649" Approved Approved Nucleoplasm,Cytosol NA NA 21000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA040852: AB_10794069, HPA063649: AB_2685074" "unprognostic (8.62e-3)" "unprognostic (8.00e-3)" "prognostic favorable (1.04e-4)" "unprognostic (3.58e-2)" "unprognostic (1.79e-1)" "unprognostic (1.98e-2)" "unprognostic (6.09e-2)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (5.14e-3)" "unprognostic (2.62e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (1.22e-1)" "unprognostic (2.50e-2)" "unprognostic (6.89e-2)" "unprognostic (5.02e-2)" 18.5 18.3 3.3 15.1 4.6 6.4 16.7 3.3 4.2 13.7 8.4 26.0 25.0 10.6 11.9 29.0 10.7 10.6 13.2 3.8 3.5 16.7 51.8 13.8 13.7 3.6 3.7 7.5 36.5 10.2 12.1 15.5 3.5 14.2 26.0 1.5 22.6 7.4 9.7 16.2 21.3 12.5 3.5 14.0 19.6 4.5 3.9 9.6 11.3 5.9 14.2 21.7 15.7 3.6 26.1 56.5 12.3 32.7 21.8 33.7 27.4 39.8 47.3 38.8 41.6 42.5 31.5 41.0 16.3 69.4 20.2 35.1 25.3 48.5 39.2 30.7 29.0 13.6 33.0 73.8 40.4 36.9 31.6 50.4 33.7 41.1 37.9 18.1 40.1 24.5 18.9 39.6 26.0 68.3 37.9 33.9 52.8 60.0 35.8 47.2 27.4 82.8 43.5 45.0 23.5 43.7 32.7 71.4 23.9 19.5 46.4 31.7 47.7 27.8 31.5 76.6 39.5 48.2 43.3 51.5 23.4 45.5 38.0 210.5 16.5 3.2 7.9 13.0 11.7 9.5 7.0 10.2 12.1 7.8 7.7 7.5 26.5 6.2 8.4 10.9 5.7 10.9 3.3 4.6 3.3 4.2 3.8 3.5 3.6 3.7 3.5 3.5 3.9 3.6 16.5 16.0 24.1 12.7 18.4 3.8 11.6 7.7 14.8 4.7 10.6 9.5 3.1 4.3 28.8 0.0 14.6 8.9 11.9 11.2 9.8 16.3 0.9 15.9 32.0 11.7 7.7 9.0 29.3 28.5 11.9 16.6 23.9 38.5 22.8 12.9 2.5 12.8 5.5 1.7 26.1 21.2 2.0 4.7 1.7 0.9 6.2 10.4 1.8 21.5 9.6 2.5 9.2 22.6 21.6 23.3 9.7 2.2 49.5 12.6 12.3 17.4 16.8 9.0 0.0 13.5 9.8 2.0 4.2 27.0 4.1 10.7 16.0 13.1 12.6 14.9 PPIA CYPA ENSG00000196262 "Peptidylprolyl isomerase A" P62937 7 44796680-44824564 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB004655, HPA058345" Uncertain "Secreted to blood" NA NA 230000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "CAB004655: AB_425607, HPA058345: AB_2683685" "unprognostic (3.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.86e-2)" "unprognostic (9.27e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (2.27e-6)" "unprognostic (1.12e-3)" "unprognostic (3.30e-2)" "unprognostic (3.92e-2)" "unprognostic (8.68e-3)" "unprognostic (2.52e-1)" "unprognostic (6.35e-3)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" "unprognostic (7.84e-2)" "unprognostic (1.16e-1)" 1148.4 1085.6 1707.2 714.4 1757.6 1052.9 1368.0 1733.9 2245.6 943.7 1718.8 1352.6 603.7 854.8 981.6 2149.0 771.3 548.8 781.6 1785.4 1791.4 1412.8 1318.6 1099.2 1067.1 1857.4 1728.1 799.5 967.7 1286.3 670.1 805.9 1860.7 766.1 1196.0 496.7 1020.3 782.9 566.1 1516.0 953.4 943.4 1767.2 1134.4 896.7 366.0 1742.4 2333.2 884.9 517.9 1647.3 1339.3 1208.7 1822.8 2141.8 3020.1 3731.1 2509.6 2798.6 4154.8 1115.0 3173.6 4588.0 5531.3 5393.2 3414.3 3127.1 4614.1 1893.1 3828.8 6554.2 3209.5 4495.7 5727.5 5062.6 2674.3 3204.3 1883.6 3911.6 4682.5 2255.3 3890.0 2246.2 3103.5 3820.5 3988.9 4295.5 2888.1 5717.2 3277.9 3933.2 3789.6 5790.6 3665.7 4667.5 7562.4 4612.9 7628.9 3689.2 3554.4 2050.1 5969.7 8018.9 4215.4 2548.3 2218.7 2500.5 7185.8 2493.3 4091.8 4303.8 5202.3 2587.0 2865.0 3656.5 2027.1 4050.5 3861.7 6522.3 9409.0 2614.0 4314.6 4455.2 475.6 1239.3 594.8 1421.6 1449.2 1534.2 2104.8 1500.3 1491.1 2196.1 1769.5 1217.2 1394.4 133.3 1349.0 1374.8 2618.5 2085.4 3631.4 1707.2 1757.6 1733.9 2245.6 1785.4 1791.4 1857.4 1728.1 1860.7 1767.2 1742.4 1822.8 713.8 794.9 759.9 37.2 1037.1 866.6 867.8 1097.5 1878.1 94.3 1226.2 1628.0 47.6 526.1 743.6 603.2 18.8 852.7 1067.7 658.4 1414.6 1172.4 78.2 539.3 770.8 719.7 529.6 1120.3 57.3 1218.7 1683.7 672.4 820.1 862.1 622.1 650.0 669.7 766.9 1582.1 111.0 50.4 1003.5 587.9 1110.0 786.1 81.4 582.2 988.1 691.9 41.2 1283.2 221.6 995.9 27.2 79.8 1222.6 715.0 613.1 1215.3 922.1 831.6 1636.8 481.4 101.5 394.4 588.7 942.7 366.7 246.1 2608.3 990.4 609.2 924.5 1157.5 1262.6 947.0 PPIAL4A "COAS2, PPIAL4, PPIAL4B" ENSG00000263353 "Peptidylprolyl isomerase A like 4A" Q9Y536 1 120889746-120890405 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 9 "Distal tubular cells: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 1.6;NB-4: 1.8;SK-BR-3: 1.9" HPA058345 Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA058345: AB_2683685" "unprognostic (3.49e-3)" "unprognostic (2.78e-2)" "unprognostic (1.45e-1)" "unprognostic (1.42e-1)" "unprognostic (4.17e-1)" "unprognostic (1.77e-1)" "unprognostic (2.09e-1)" "unprognostic (1.42e-2)" "unprognostic (7.94e-3)" "unprognostic (1.72e-2)" "unprognostic (1.91e-1)" "unprognostic (7.11e-2)" "unprognostic (5.32e-2)" "unprognostic (3.66e-2)" "unprognostic (1.55e-1)" "unprognostic (1.83e-2)" "unprognostic (1.74e-1)" 0.0 0.2 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.7 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.4 0.8 1.8 1.0 0.0 0.0 0.3 0.6 0.8 0.0 0.0 0.4 0.1 0.1 1.9 0.2 0.0 1.3 1.1 0.3 1.2 0.4 1.2 0.7 0.5 0.4 1.0 1.1 0.7 1.3 0.0 0.4 0.2 0.4 0.4 0.4 0.8 0.6 0.7 0.9 0.6 0.4 0.7 0.0 0.7 0.3 0.9 0.7 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPIAL4C ENSG00000263464 "Peptidylprolyl isomerase A like 4C" A0A0B4J2A2 1 149583865-149584464 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.4;lymphoid tissue: 2.2" "Cell type enriched" "Detected in single" 5 "Cardiomyocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 18.8;THP-1: 22.5" HPA058345 Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA058345: AB_2683685" "unprognostic (3.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (7.93e-2)" "unprognostic (5.98e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-1)" "unprognostic (6.61e-2)" "unprognostic (2.25e-1)" 0.3 1.9 0.5 2.2 0.5 0.2 0.4 0.7 0.9 0.4 0.4 0.8 3.4 0.9 0.0 0.1 0.1 0.1 0.0 0.5 0.5 0.7 0.3 1.0 2.1 0.5 0.5 0.2 0.0 0.2 0.2 0.8 0.5 0.4 0.2 0.0 0.0 0.1 0.5 0.3 1.8 0.1 0.4 1.7 0.8 0.0 0.5 0.0 0.1 0.0 0.8 0.1 0.1 0.5 4.1 0.0 0.5 3.2 0.2 0.5 2.8 0.5 0.2 1.2 0.9 0.0 6.4 1.9 2.4 0.0 3.1 4.5 0.0 0.3 0.8 4.8 0.0 0.4 0.0 0.0 0.1 1.1 1.7 0.2 1.0 0.8 0.4 0.0 0.0 0.2 0.9 6.1 0.9 0.7 7.4 18.8 7.6 0.8 0.1 7.2 0.1 12.2 0.0 0.0 5.0 6.8 0.8 13.1 7.9 0.0 6.1 22.5 0.0 4.4 6.1 3.2 10.5 4.4 6.9 11.9 5.0 5.8 9.8 1.6 3.8 1.6 4.1 5.2 4.8 7.0 4.6 4.5 8.0 6.2 3.8 5.0 0.3 3.3 3.6 8.3 6.1 12.0 0.5 0.5 0.7 0.9 0.5 0.5 0.5 0.5 0.5 0.4 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPIAL4D ENSG00000256374 "Peptidylprolyl isomerase A like 4D" F5H284 1 145241630-145242124 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Langerhans cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA058345 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "HPA058345: AB_2683685" "unprognostic (9.32e-2)" "unprognostic (1.33e-1)" "unprognostic (3.05e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.8 0.1 0.6 1.9 0.6 2.4 1.2 0.8 1.7 1.6 1.1 1.5 0.0 1.2 1.3 1.7 2.2 3.3 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 PPIAL4E ENSG00000271567 "Peptidylprolyl isomerase A like 4E" A0A075B759 1 144372875-144373659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058345 Uncertain NA NA "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA058345: AB_2683685" "unprognostic (6.97e-2)" "unprognostic (5.22e-2)" "unprognostic (2.28e-1)" 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PPIAL4F ENSG00000279782 "Peptidylprolyl isomerase A like 4F" P0DN26 1 144592868-144593652 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058345 Uncertain NA NA "HPA058345: AB_2683685" "unprognostic (1.08e-1)" "unprognostic (2.22e-2)" "unprognostic (2.02e-1)" 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPIAL4G ENSG00000236334 "Peptidylprolyl isomerase A like 4G" P0DN37 1 148482548-148483302 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.8;Langerhans cells: 7.4;NK-cells: 9.2;Suprabasal keratinocytes: 12.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HL-60: 1.9;TIME: 1.9" HPA058345 Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 6: Brain - Smell perception" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "HPA058345: AB_2683685" "unprognostic (2.17e-3)" "unprognostic (3.63e-1)" "unprognostic (4.83e-1)" "unprognostic (2.26e-1)" "unprognostic (2.37e-1)" "unprognostic (2.11e-1)" "unprognostic (3.95e-1)" "unprognostic (2.67e-2)" "unprognostic (1.79e-1)" 0.1 0.5 0.7 0.5 0.4 1.0 0.1 1.5 0.7 0.0 0.1 0.2 0.7 0.1 0.4 0.0 0.0 0.0 0.1 0.4 0.3 0.3 0.1 0.3 0.7 0.2 0.3 0.3 0.1 0.1 0.0 0.0 0.3 0.3 0.1 1.1 0.4 0.0 0.9 0.7 0.7 0.0 0.1 0.4 0.4 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.8 0.9 0.1 1.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.7 0.0 1.9 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.4 1.1 0.0 0.3 0.0 0.9 0.4 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.8 1.4 0.2 0.6 0.9 0.0 1.9 0.2 1.1 1.2 0.3 1.1 0.8 0.9 0.0 0.5 0.4 0.2 0.2 0.5 1.2 0.4 0.7 1.2 0.8 0.7 0.4 0.8 0.6 0.7 0.0 2.2 1.7 0.3 1.1 0.6 0.7 0.4 1.5 0.7 0.4 0.3 0.2 0.3 0.3 0.1 0.5 0.6 0.1 0.0 0.6 0.0 1.0 6.8 0.4 0.8 0.0 1.8 0.3 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.1 1.4 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 1.3 0.1 0.4 0.5 0.2 1.7 0.0 0.0 0.0 1.2 7.4 0.3 0.0 0.2 1.8 0.0 0.4 0.2 9.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.1 1.1 0.0 0.5 2.6 0.0 0.1 0.0 12.5 0.1 3.2 0.1 0.0 0.2 PPIAL4H ENSG00000270339 "Peptidylprolyl isomerase A like 4H" A0A075B767 1 146344131-146344790 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "THP-1: 1.2" HPA058345 Uncertain NA NA "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "HPA058345: AB_2683685" "unprognostic (1.35e-1)" "unprognostic (2.13e-3)" "unprognostic (2.34e-1)" "unprognostic (2.76e-2)" "unprognostic (2.34e-1)" "unprognostic (2.84e-2)" 0.0 0.0 1.1 0.0 1.0 0.0 0.1 2.4 1.6 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.0 0.0 0.0 0.1 0.8 0.8 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 2.4 1.6 1.1 1.0 0.8 0.8 0.8 0.8 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPIB "B, CYP-S1, CYPB, OI9, PPIase, SCYLP" ENSG00000166794 "Peptidylprolyl isomerase B" P23284 15 64155740-64163134 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Isomerase, Rotamase" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1473.7;Plasma cells: 2242.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011487, HPA012720" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" "Secreted to blood" No No 33000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" Nucleoplasm "CAB011487: AB_443295, HPA012720: AB_1847399" "unprognostic (3.00e-3)" "unprognostic (5.65e-3)" "unprognostic (2.81e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.65e-1)" "unprognostic (1.07e-3)" "unprognostic (3.69e-2)" "unprognostic (1.27e-2)" "unprognostic (7.19e-2)" "unprognostic (8.80e-3)" "unprognostic (2.87e-1)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.02e-11)" "unprognostic (7.05e-2)" "unprognostic (3.77e-2)" "unprognostic (1.82e-1)" "unprognostic (3.90e-2)" 375.5 377.5 230.7 449.5 240.3 571.9 361.9 247.9 259.2 611.5 257.2 401.0 365.0 383.9 899.0 298.8 401.5 379.2 262.0 229.7 256.9 312.3 737.4 351.1 344.5 258.1 241.4 386.2 644.2 345.4 416.8 515.2 255.1 375.7 411.3 72.3 513.1 488.6 62.2 205.5 334.3 482.4 247.0 360.5 375.0 110.0 254.9 315.6 672.8 91.1 346.4 510.9 295.6 262.6 675.6 847.9 736.7 1666.7 2577.0 1492.3 641.9 1570.3 2108.3 1248.7 1472.3 1242.6 1223.1 653.6 1227.4 2513.0 1235.3 1067.7 1384.6 1080.4 641.1 406.2 491.0 914.5 915.3 1643.7 2682.9 915.0 778.1 1374.2 1149.4 725.9 1751.3 1516.7 1539.2 301.1 645.9 2174.7 966.0 1102.6 280.6 1404.9 625.1 1879.0 529.5 520.6 784.1 3347.9 1312.7 1062.6 410.5 647.7 726.0 1224.5 1194.2 1086.0 727.6 2767.0 927.6 1213.7 975.8 679.2 1079.4 1152.5 1269.5 693.4 1129.0 1478.0 1238.2 716.7 712.5 491.7 929.6 547.3 931.8 827.8 645.0 762.4 930.9 541.4 411.3 558.0 347.5 668.1 369.3 2643.5 569.3 1512.3 230.7 240.3 247.9 259.2 229.7 256.9 258.1 241.4 255.1 247.0 254.9 262.6 389.3 125.0 209.0 16.6 375.3 160.2 426.2 614.6 234.5 34.5 264.3 303.8 0.8 270.2 328.7 272.2 31.3 625.9 560.0 271.0 90.1 665.1 19.0 295.8 910.1 285.0 297.0 172.6 10.2 566.4 1473.7 627.8 441.4 494.2 181.2 540.4 322.7 473.2 630.1 45.4 15.8 603.9 205.4 216.9 333.4 29.5 456.3 316.6 281.1 19.7 299.1 149.1 368.7 35.2 37.0 435.1 338.9 393.1 2242.6 569.3 338.6 287.4 168.2 43.7 230.1 204.3 445.6 38.4 76.6 337.0 144.8 1118.9 352.3 674.0 477.2 422.3 PPIC CYPC ENSG00000168938 "Peptidylprolyl isomerase C" P45877 5 123023250-123036725 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 251.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 229.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039163 Approved "Intracellular and membrane" NA NA 3700000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA039163: AB_2676374" "unprognostic (7.81e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" "unprognostic (7.49e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (3.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.70e-1)" "unprognostic (2.38e-1)" "unprognostic (4.27e-2)" "unprognostic (2.43e-2)" 37.0 20.6 5.3 16.4 5.6 0.2 30.4 6.8 7.0 42.3 12.2 41.4 37.3 31.0 36.5 46.8 14.8 33.5 44.4 5.2 5.8 24.9 28.9 27.0 7.6 6.4 6.3 16.2 30.3 20.9 6.2 48.3 6.2 23.4 49.9 4.9 31.7 24.0 41.2 20.2 32.3 45.2 6.1 7.7 22.4 9.0 6.7 5.8 47.2 33.3 14.2 45.8 28.8 5.8 19.6 16.8 6.4 136.2 229.7 104.6 26.9 54.4 42.3 27.8 56.7 28.1 128.6 0.0 94.2 147.1 83.3 21.9 18.9 68.6 22.1 0.1 33.1 27.8 60.7 32.8 58.9 0.0 14.7 65.8 51.5 32.5 34.0 49.9 58.1 0.0 7.9 0.0 20.1 116.5 0.1 0.3 11.6 120.9 29.0 0.0 14.5 0.0 87.7 67.0 8.5 14.9 106.7 51.1 12.1 77.8 72.0 61.8 64.8 52.9 32.7 18.5 23.9 0.2 0.1 0.4 45.9 0.2 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.6 6.8 7.0 5.2 5.8 6.4 6.3 6.2 6.1 6.7 5.8 214.1 32.1 16.5 6.2 1.6 47.4 52.3 251.7 30.7 16.9 63.9 47.5 46.4 61.5 149.0 73.5 4.2 60.1 0.6 134.0 29.4 201.5 1.7 52.4 94.8 106.5 12.7 0.0 0.8 126.4 65.2 198.2 55.0 50.8 1.3 54.2 80.7 57.8 43.2 0.0 2.2 177.1 207.5 4.2 40.3 4.2 112.5 6.9 32.0 5.6 3.2 2.8 0.0 1.0 0.3 90.3 181.0 100.1 0.6 48.2 189.0 81.7 110.5 4.4 39.5 22.7 87.5 41.6 37.8 118.6 49.3 25.0 3.4 61.2 117.0 81.5 PPID CYP-40 ENSG00000171497 "Peptidylprolyl isomerase D" Q08752 4 158709127-158723396 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Protein transport, Transport" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019520, HPA019692" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA 480000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA019520: AB_1847400, HPA019692: AB_1847401" "unprognostic (4.26e-2)" "unprognostic (2.03e-2)" "unprognostic (8.91e-3)" "unprognostic (8.17e-3)" "unprognostic (1.50e-1)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.62e-2)" "unprognostic (4.72e-2)" "unprognostic (5.92e-2)" "unprognostic (4.54e-2)" "unprognostic (1.46e-2)" "unprognostic (2.66e-3)" "unprognostic (8.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.64e-1)" "unprognostic (1.09e-1)" 26.8 38.3 38.0 24.4 40.2 25.1 22.8 40.4 77.6 25.4 46.4 33.9 50.6 24.2 19.0 27.7 24.1 18.8 49.6 40.1 44.2 39.5 87.6 19.8 28.6 39.0 39.4 24.2 31.7 17.0 28.6 21.6 40.2 23.5 20.3 36.2 23.3 18.7 88.9 36.1 45.3 18.9 39.6 29.1 29.0 24.1 42.2 24.3 23.9 45.5 25.8 27.4 24.0 46.9 46.7 42.3 41.8 57.7 60.7 45.2 63.1 44.9 24.3 40.3 30.4 55.4 30.9 48.9 19.7 42.0 63.4 35.1 127.9 51.5 48.8 162.9 44.4 87.5 36.5 76.9 46.8 55.6 63.0 28.9 41.2 34.6 51.5 52.0 44.6 81.9 111.0 84.4 45.5 44.6 80.0 49.9 57.9 75.5 55.8 35.9 20.7 41.7 44.6 23.0 70.2 47.1 33.8 69.2 65.6 60.0 31.9 52.2 43.7 40.1 45.3 44.7 60.2 48.3 107.2 62.0 51.1 59.4 41.1 68.8 23.9 55.2 31.1 35.4 36.0 22.3 30.2 29.1 26.4 25.4 30.9 32.0 32.9 40.5 37.7 26.9 37.0 28.0 38.0 40.2 40.4 77.6 40.1 44.2 39.0 39.4 40.2 39.6 42.2 46.9 29.2 6.4 13.4 13.1 24.8 10.1 29.7 17.5 9.1 30.2 19.1 20.8 59.7 25.8 27.9 27.6 22.9 41.5 38.7 17.1 37.2 39.2 39.0 66.1 39.9 25.1 19.6 17.4 24.3 23.0 49.5 24.3 14.3 28.5 32.3 24.4 17.2 18.5 41.9 75.7 28.6 28.3 22.4 17.0 14.7 23.1 20.5 26.0 14.2 9.4 51.6 23.3 48.4 15.1 28.3 29.5 27.4 22.6 22.3 31.6 39.7 33.7 62.3 32.3 6.6 17.7 58.2 96.0 77.5 16.9 11.8 47.6 33.7 33.7 32.0 20.2 PPIE "CyP-33, MGC111222, MGC3736" ENSG00000084072 "Peptidylprolyl isomerase E" Q9UNP9 1 39692182-39763914 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA019357, HPA020131" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA019357: AB_2670131, HPA020131: AB_1847405" "unprognostic (2.94e-1)" "unprognostic (4.32e-2)" "unprognostic (6.34e-2)" "unprognostic (6.97e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.52e-2)" "unprognostic (2.69e-1)" "unprognostic (3.88e-3)" "unprognostic (1.25e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (5.86e-2)" "unprognostic (3.95e-1)" "unprognostic (9.06e-2)" "unprognostic (1.00e-1)" 26.0 27.9 22.3 16.1 22.9 18.5 26.8 22.7 26.5 31.4 20.2 41.1 18.3 33.8 24.9 31.8 35.0 18.1 33.3 22.3 22.8 33.0 33.7 23.3 27.2 22.6 22.0 36.7 40.2 23.8 27.7 20.7 22.9 32.3 22.5 20.9 26.2 23.6 43.1 29.5 29.2 25.4 23.7 32.7 31.7 41.8 22.3 20.6 29.1 30.3 28.2 36.4 29.5 24.6 24.5 34.4 37.2 25.7 40.9 36.9 14.3 40.8 42.7 58.7 56.4 32.8 64.8 68.4 52.2 47.9 34.5 32.8 57.1 52.3 68.8 41.1 38.4 75.6 37.4 9.7 50.9 68.4 36.3 32.8 47.2 53.9 21.0 42.0 54.5 52.8 74.8 39.5 46.6 24.7 34.2 42.1 39.9 49.7 31.5 41.4 28.4 38.4 37.8 37.2 47.7 42.3 43.8 31.5 28.4 49.7 40.9 155.8 35.8 36.3 35.3 48.4 57.1 55.8 66.4 52.5 27.0 86.4 52.3 38.3 62.8 32.6 83.9 64.8 82.8 107.5 89.4 83.8 74.1 109.2 103.5 82.4 6.0 123.2 70.0 63.8 101.3 122.5 22.3 22.9 22.7 26.5 22.3 22.8 22.6 22.0 22.9 23.7 22.3 24.6 28.2 32.1 36.7 10.7 37.0 24.9 43.1 69.8 23.9 25.9 30.3 47.5 31.8 21.5 62.1 33.1 14.6 62.5 39.3 22.8 66.5 57.5 29.2 34.6 27.7 28.7 28.8 38.3 7.7 48.4 59.3 34.0 16.3 23.4 55.2 44.1 37.9 31.1 56.1 23.5 8.8 32.9 40.7 33.4 26.9 76.3 29.8 30.0 39.2 8.4 46.8 34.0 58.7 8.0 13.6 40.0 24.1 45.1 31.7 32.0 39.3 69.8 63.4 29.7 59.2 23.3 40.1 76.1 51.4 24.5 26.3 34.8 36.6 36.3 35.9 32.9 PPIF "Cyp-D, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355334 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Necrosis" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 370.9;Macrophages: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 75.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria NA NA 320000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA077416: AB_2686840" "unprognostic (2.21e-1)" "unprognostic (5.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.72e-3)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (3.45e-1)" "unprognostic (4.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (9.37e-3)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (1.69e-3)" "unprognostic (4.88e-2)" 62.7 227.7 42.7 42.8 48.4 168.8 42.4 57.9 69.6 27.6 63.7 50.0 36.3 14.0 7.2 66.0 22.9 19.5 119.1 38.1 45.2 63.3 174.9 29.1 32.3 49.0 56.2 19.3 86.9 77.6 18.3 27.1 48.8 18.8 52.4 8.9 39.5 45.5 99.5 71.9 31.3 21.0 50.6 58.7 98.2 35.0 57.1 28.3 26.0 133.6 55.5 60.0 35.1 60.8 220.4 90.6 62.3 123.5 57.0 73.6 79.8 124.2 161.2 265.7 249.6 213.5 102.7 224.8 68.0 87.4 188.6 127.8 195.3 115.4 410.5 72.2 186.4 352.8 87.5 380.7 96.4 245.7 80.4 173.2 81.3 264.5 262.3 86.5 47.5 86.4 351.6 268.3 91.6 111.7 64.1 204.2 53.0 99.6 500.6 109.8 96.4 114.7 103.9 200.0 124.1 92.0 63.6 253.8 97.9 40.5 111.4 187.2 43.5 116.1 106.3 137.9 242.0 124.7 137.7 181.9 114.5 313.9 32.0 15.2 34.3 18.0 10.4 27.5 10.9 19.1 9.1 9.6 43.3 7.7 8.1 7.9 75.0 9.0 10.4 5.4 10.0 16.6 42.7 48.4 57.9 69.6 38.1 45.2 49.0 56.2 48.8 50.6 57.1 60.8 8.4 6.4 6.8 7.2 32.7 42.6 30.2 23.8 31.3 4.0 41.8 40.8 124.6 14.3 14.4 12.9 6.2 99.4 26.4 39.9 92.0 42.1 14.5 12.4 24.0 10.1 21.6 37.0 4.1 28.0 127.1 25.1 78.0 15.5 13.4 73.4 6.1 98.5 91.1 8.4 5.7 69.5 18.3 40.3 370.9 14.1 6.2 160.8 35.6 4.7 32.0 13.0 5.2 5.5 15.0 39.8 26.6 6.0 48.7 41.4 21.3 41.2 12.6 5.2 19.7 18.2 28.6 14.8 22.5 52.9 37.6 142.3 23.9 60.2 81.1 34.2 PPIG "CARS-Cyp, SCAF10, SRCyp" ENSG00000138398 "Peptidylprolyl isomerase G" Q13427 2 169584342-169641406 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021788, HPA057469" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" Cytosol "HPA021788: AB_1847408, HPA057469: AB_2683445" "unprognostic (2.70e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (3.49e-2)" "unprognostic (1.55e-3)" "unprognostic (3.66e-2)" "unprognostic (2.15e-3)" "unprognostic (3.15e-3)" "unprognostic (2.47e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (4.56e-4)" "unprognostic (5.23e-2)" "unprognostic (3.29e-1)" "unprognostic (3.41e-2)" "unprognostic (3.39e-2)" 26.0 23.2 23.1 28.4 22.1 54.2 27.5 28.8 58.6 27.6 22.9 26.3 26.6 28.8 31.5 27.5 23.6 22.0 25.6 21.5 29.9 29.2 47.1 24.7 36.9 24.6 25.6 26.5 21.2 32.6 25.8 28.0 24.3 27.9 26.0 29.3 26.5 22.9 27.6 25.4 29.7 21.7 22.9 32.3 27.4 20.1 23.7 36.1 29.9 26.2 35.4 26.3 26.5 25.9 56.4 25.5 70.8 35.9 35.4 42.5 63.7 58.9 42.3 45.0 45.9 66.3 58.9 94.8 52.5 44.1 55.5 50.5 56.6 48.4 65.6 68.0 45.7 129.9 36.7 88.3 34.4 136.8 58.9 36.6 54.0 58.5 64.6 40.6 50.4 53.5 142.7 76.2 49.5 43.5 101.0 81.9 100.8 45.3 25.1 90.7 71.7 90.5 53.9 81.2 60.5 41.2 63.4 47.2 68.9 52.9 44.2 78.7 52.7 53.9 43.7 38.4 52.6 41.1 65.3 126.8 38.5 68.1 54.1 31.9 22.5 36.7 22.8 25.1 26.7 32.9 30.9 29.2 18.2 38.4 33.4 27.6 40.4 21.1 31.4 30.0 26.8 17.0 23.1 22.1 28.8 58.6 21.5 29.9 24.6 25.6 24.3 22.9 23.7 25.9 159.7 221.2 175.1 53.5 188.8 151.4 191.4 185.9 101.3 204.6 120.8 156.1 148.4 107.2 169.5 93.8 54.2 170.0 160.1 91.6 80.3 103.1 11.0 104.6 142.3 141.1 104.8 163.5 82.4 103.3 177.0 142.4 66.8 126.3 179.1 115.8 121.7 181.2 151.7 220.4 81.8 135.8 116.0 130.3 126.5 15.6 142.0 129.6 110.3 46.9 152.4 137.6 133.9 53.8 69.7 93.9 118.0 146.7 130.1 161.8 121.1 113.8 132.2 109.1 164.3 150.2 193.9 276.4 183.8 108.3 172.8 205.5 166.7 147.1 149.9 167.7 PPIH "CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP" ENSG00000171960 "Peptidylprolyl isomerase H" O43447 1 42658335-42676758 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059019 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "HPA059019: AB_2683885" "unprognostic (7.93e-3)" "unprognostic (5.49e-3)" "unprognostic (2.53e-2)" "unprognostic (6.42e-2)" "unprognostic (3.79e-2)" "unprognostic (1.95e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (1.09e-1)" "unprognostic (2.37e-2)" "unprognostic (1.82e-2)" "unprognostic (2.84e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.78e-9)" "unprognostic (6.59e-3)" "unprognostic (4.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" 22.9 23.2 22.1 27.8 23.1 56.8 27.7 23.7 29.5 24.8 20.8 33.2 24.4 23.5 25.4 36.4 23.5 17.9 25.8 23.0 22.5 22.1 17.5 22.4 44.5 22.2 22.0 25.8 19.2 18.3 13.4 24.7 22.7 21.2 32.8 22.4 23.9 18.3 19.8 27.5 27.8 21.5 21.8 32.3 23.4 22.9 22.5 60.3 26.0 21.1 50.4 26.6 25.8 23.3 105.8 66.4 80.1 113.3 24.9 51.5 101.4 67.6 50.1 127.4 114.4 98.1 111.8 171.5 85.9 52.8 61.7 82.3 150.8 108.2 133.9 150.2 119.7 156.4 104.4 98.6 21.4 322.0 90.7 31.2 57.5 117.9 90.6 49.1 60.6 161.2 205.7 91.7 63.8 84.2 250.1 451.0 200.4 100.4 77.7 136.8 150.2 152.2 64.1 64.8 59.2 113.5 59.6 101.1 77.4 100.8 54.5 465.0 48.1 53.2 143.1 77.0 171.7 60.0 140.2 319.6 62.8 294.9 94.8 29.7 15.1 33.3 35.0 23.5 33.3 33.6 35.7 39.9 20.7 32.9 36.1 43.5 3.6 36.4 21.8 25.9 38.2 25.0 22.1 23.1 23.7 29.5 23.0 22.5 22.2 22.0 22.7 21.8 22.5 23.3 31.3 19.2 20.7 9.8 48.1 28.9 48.2 51.7 38.7 10.0 30.1 44.4 14.1 11.5 25.8 22.0 4.2 62.5 37.7 15.7 45.0 29.4 33.2 23.4 27.4 25.1 21.5 49.8 12.7 26.4 104.5 25.5 27.5 21.6 31.0 46.9 19.2 11.2 52.1 5.0 9.6 27.3 34.6 18.6 25.6 7.3 29.2 28.5 16.0 9.4 26.2 22.2 52.5 11.6 11.6 25.8 17.6 21.4 45.6 28.0 16.1 34.1 19.6 16.1 19.7 21.5 42.0 19.7 32.3 54.6 21.5 37.9 42.7 46.4 40.0 38.7 PPIL1 CYPL1 ENSG00000137168 "Peptidylprolyl isomerase like 1" Q9Y3C6 6 36854827-36874803 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 58.7;Extravillous trophoblasts: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062916 Supported Nucleoli NA NA 21000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli "HPA062916: AB_2684904" "unprognostic (3.51e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-3)" "unprognostic (1.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.81e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (2.01e-1)" "unprognostic (3.37e-2)" "prognostic favorable (4.90e-4)" "unprognostic (6.58e-2)" "unprognostic (5.49e-2)" "unprognostic (8.99e-2)" "unprognostic (1.30e-1)" "unprognostic (2.30e-1)" "unprognostic (3.39e-2)" "unprognostic (2.15e-2)" 12.4 21.7 20.3 19.1 21.9 11.4 18.4 22.6 27.3 15.0 23.8 14.7 13.2 15.7 19.1 17.0 23.0 10.7 42.8 20.0 25.2 18.9 21.5 10.5 21.9 22.0 22.0 17.7 14.3 21.7 12.0 22.3 23.3 16.8 17.6 29.1 19.5 17.6 18.5 9.5 11.3 22.9 24.1 9.5 12.9 23.2 22.2 18.6 33.2 20.7 24.6 20.5 8.0 22.8 69.2 50.0 111.2 78.5 19.7 31.5 77.5 60.9 41.0 82.7 70.0 89.7 39.7 87.7 75.5 41.9 105.5 55.4 135.1 92.7 96.2 81.3 114.6 102.7 33.6 147.7 53.5 89.3 40.8 24.7 48.7 62.3 118.9 31.8 75.5 79.1 202.4 48.0 63.3 71.2 101.9 69.8 92.3 108.5 57.9 79.4 100.2 92.0 63.2 53.5 140.0 68.5 41.8 51.4 102.5 83.5 76.3 100.2 44.0 66.7 69.0 58.5 98.8 57.0 145.2 153.0 23.7 183.7 139.4 1.6 4.8 1.3 14.7 6.2 19.7 10.3 12.1 13.9 9.2 7.4 13.4 15.9 1.2 7.3 3.4 7.8 10.2 9.8 20.3 21.9 22.6 27.3 20.0 25.2 22.0 22.0 23.3 24.1 22.2 22.8 5.7 6.4 7.5 2.9 10.8 3.1 18.6 12.2 5.7 16.9 9.0 10.5 45.8 8.6 8.3 5.5 4.2 58.7 6.6 3.3 23.5 25.7 32.0 10.3 14.2 12.3 3.6 22.7 6.5 20.3 72.3 12.2 7.7 7.7 10.8 16.3 5.0 8.2 30.1 16.8 8.6 11.4 4.1 3.3 3.6 11.7 6.8 6.4 7.2 1.9 9.2 41.0 11.3 7.5 5.4 22.1 5.5 12.4 15.0 13.5 3.3 17.1 13.5 15.5 6.6 6.1 12.8 25.7 51.0 10.6 4.5 25.3 9.2 21.1 11.9 8.6 PPIL3 CyPJ ENSG00000240344 "Peptidylprolyl isomerase like 3" Q9H2H8 2 200870907-200889303 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040765, HPA062187" Approved Approved Nucleoplasm,Nucleoli NA NA 120000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "HPA040765: AB_2677125, HPA062187: AB_2684706" "unprognostic (8.96e-3)" "unprognostic (6.07e-2)" "unprognostic (5.34e-2)" "unprognostic (8.16e-2)" "unprognostic (2.69e-2)" "unprognostic (9.61e-2)" "unprognostic (8.31e-2)" "unprognostic (8.05e-2)" "unprognostic (1.40e-2)" "prognostic favorable (1.19e-4)" "unprognostic (5.23e-2)" "unprognostic (6.60e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.14e-1)" "unprognostic (5.96e-2)" "unprognostic (2.21e-2)" "unprognostic (4.87e-2)" 13.0 16.4 15.2 19.8 14.9 35.1 25.4 17.0 22.3 15.7 13.9 19.0 14.6 20.2 28.4 18.6 22.5 13.0 18.2 14.6 16.8 18.4 21.9 15.0 32.2 15.7 15.5 35.4 12.1 14.0 14.9 17.7 16.8 15.1 19.5 25.8 17.1 18.2 18.0 18.0 18.1 12.4 15.4 17.5 19.0 21.1 15.5 30.1 20.8 11.1 32.5 16.2 12.5 18.2 19.9 18.3 53.0 23.5 42.5 90.8 17.5 32.0 35.3 37.1 37.2 13.0 37.5 19.5 32.0 35.4 41.9 24.6 19.3 38.1 33.2 41.4 43.8 84.0 48.3 90.6 21.3 79.7 39.8 32.7 37.7 30.3 47.1 62.0 25.3 38.4 67.4 46.3 46.3 32.4 61.7 67.2 32.9 19.8 28.9 23.3 30.5 29.1 49.6 30.4 22.2 21.1 31.3 29.9 51.7 62.3 24.6 36.9 34.2 51.4 28.8 31.2 26.2 45.5 51.0 94.2 39.6 36.2 33.7 36.2 17.5 19.7 17.5 16.4 25.5 35.2 20.9 17.7 30.9 26.7 25.3 27.6 4.5 31.8 23.1 25.6 30.3 14.6 15.2 14.9 17.0 22.3 14.6 16.8 15.7 15.5 16.8 15.4 15.5 18.2 12.5 0.0 11.5 16.0 33.6 31.7 43.1 71.5 37.5 12.0 23.7 28.2 18.5 15.7 30.4 16.5 10.4 50.3 24.8 9.7 56.7 26.0 44.1 16.1 21.4 16.2 9.5 25.5 19.3 16.1 51.6 22.1 16.3 13.4 26.0 17.2 13.6 19.4 47.0 3.3 18.1 25.3 48.8 32.1 59.1 9.5 36.7 26.8 28.4 9.4 30.2 23.1 37.0 15.1 19.7 18.2 18.1 28.2 24.5 15.9 25.4 59.7 28.7 11.9 19.7 18.2 39.6 45.7 22.6 34.5 46.3 30.8 31.1 8.9 29.4 35.6 PPIL4 ENSG00000131013 "Peptidylprolyl isomerase like 4" Q8WUA2 6 149504495-149546043 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031599, HPA031600" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "HPA031599: AB_2673950, HPA031600: AB_10600928" "unprognostic (6.12e-2)" "unprognostic (4.90e-2)" "unprognostic (3.85e-2)" "unprognostic (8.42e-2)" "unprognostic (7.53e-2)" "unprognostic (6.36e-3)" "unprognostic (2.91e-3)" "unprognostic (2.22e-1)" "unprognostic (4.22e-2)" "unprognostic (1.09e-1)" "unprognostic (2.38e-1)" "unprognostic (4.62e-2)" "unprognostic (3.88e-2)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" "unprognostic (8.50e-2)" "unprognostic (7.94e-2)" 19.6 19.2 12.3 15.6 15.0 36.4 20.3 19.8 18.3 18.1 9.6 15.4 14.2 20.1 25.7 13.7 16.5 18.9 15.9 13.1 18.0 17.9 22.9 16.1 17.2 10.6 12.8 27.3 14.8 18.8 18.8 22.7 10.9 19.2 16.0 13.1 15.8 15.2 10.7 14.4 14.6 14.7 11.1 17.4 16.4 16.3 17.0 18.5 25.7 11.5 17.1 20.9 16.9 15.8 22.7 12.0 41.0 34.7 23.8 30.9 38.1 43.8 41.1 46.4 49.2 25.1 22.8 23.8 29.4 33.9 27.9 20.1 31.5 16.5 73.1 34.7 29.7 26.4 27.0 43.9 37.3 49.2 21.6 24.3 27.8 47.6 39.7 26.2 25.7 17.1 58.1 14.0 36.5 24.2 28.1 41.8 32.6 22.6 18.5 37.2 37.7 11.9 35.6 17.0 24.1 18.4 52.0 22.4 31.7 28.2 26.5 35.1 31.0 30.8 24.3 55.1 42.3 18.4 9.9 37.0 26.3 38.7 45.5 34.1 17.1 20.4 15.1 19.9 21.0 23.7 19.5 17.5 18.2 17.9 24.5 18.8 14.5 32.0 19.3 17.9 23.7 16.5 12.3 15.0 19.8 18.3 13.1 18.0 10.6 12.8 10.9 11.1 17.0 15.8 54.8 67.3 70.7 25.1 49.7 48.8 56.4 49.0 30.7 46.2 29.5 34.9 45.6 18.6 59.7 46.0 8.4 50.4 48.4 16.9 43.0 42.0 24.4 57.6 55.7 43.2 23.3 25.4 37.3 26.3 46.2 76.2 20.9 48.2 77.1 30.9 33.5 21.3 37.3 28.6 34.7 22.9 48.8 25.2 43.8 12.0 61.8 38.3 40.9 21.5 45.5 42.0 28.8 27.2 41.1 32.2 21.9 56.1 29.4 33.8 19.7 37.6 71.9 37.1 52.6 66.1 70.5 75.9 59.3 22.5 45.3 65.3 53.4 47.7 22.3 43.0 PPWD1 KIAA0073 ENSG00000113593 "Peptidylprolyl isomerase domain and WD repeat containing 1" Q96BP3 5 65563236-65587549 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019353, HPA019360" Enhanced Supported "Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Nuclear bodies" "HPA019353: AB_1855668, HPA019360: AB_1855669" "unprognostic (3.31e-2)" "unprognostic (2.07e-2)" "unprognostic (6.78e-2)" "unprognostic (2.85e-1)" "unprognostic (9.61e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (2.19e-4)" "unprognostic (1.37e-1)" "unprognostic (4.97e-2)" "unprognostic (1.09e-1)" "unprognostic (7.84e-3)" "unprognostic (5.72e-2)" "prognostic unfavorable (6.72e-4)" "unprognostic (2.40e-1)" "unprognostic (1.18e-1)" "unprognostic (2.15e-1)" "unprognostic (1.30e-2)" 15.0 12.1 12.3 18.2 14.6 27.6 17.2 16.5 16.4 17.3 13.4 14.7 13.4 19.0 17.8 13.5 16.1 15.7 13.5 12.4 13.2 13.0 15.5 14.9 30.0 13.6 12.8 22.9 14.0 15.5 14.7 19.6 13.4 15.0 19.2 14.7 12.7 13.7 13.2 22.2 17.1 13.2 12.9 22.6 14.4 18.1 13.0 32.9 16.3 15.6 26.0 13.7 15.2 18.5 36.5 23.6 35.1 35.2 30.6 36.9 38.8 34.5 25.3 36.5 45.5 37.8 35.4 41.5 28.5 24.3 49.1 32.3 38.4 35.5 49.8 35.7 32.3 26.0 40.0 31.1 25.9 23.9 26.4 29.2 15.3 35.5 25.5 27.0 32.3 31.6 35.3 28.8 28.8 35.8 40.0 31.6 24.7 15.2 13.3 35.4 46.7 35.1 21.2 29.5 18.1 14.8 34.8 14.5 33.1 26.8 21.5 30.8 24.9 20.2 29.2 22.4 52.9 17.1 26.3 45.5 22.3 35.8 21.4 35.0 15.1 31.6 26.1 19.3 32.0 25.8 29.1 29.9 21.2 19.1 36.1 31.0 14.3 26.5 24.0 11.8 38.1 23.4 12.3 14.6 16.5 16.4 12.4 13.2 13.6 12.8 13.4 12.9 13.0 18.5 25.1 28.9 22.4 28.1 36.0 12.4 14.9 15.4 18.2 14.2 9.1 12.8 19.8 7.2 22.1 11.0 8.4 27.7 27.0 6.9 9.8 8.7 76.8 16.4 28.7 20.7 9.6 21.5 37.2 7.7 14.4 21.1 15.8 13.8 11.4 32.6 18.9 6.0 11.8 6.7 46.8 14.9 8.2 16.4 11.9 41.7 20.2 15.2 14.2 23.4 22.6 11.8 23.7 42.3 67.1 8.9 14.7 18.8 29.4 6.6 10.0 7.9 17.8 20.9 6.6 19.9 17.8 32.5 33.7 13.2 11.8 25.2 35.4 15.8 11.4 9.0 PTGDS "L-PGDS, PGDS" ENSG00000107317 "Prostaglandin D2 synthase" P41222 9 136975092-136981742 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Mast cell degranulation, Prostaglandin biosynthesis, Prostaglandin metabolism, Transport" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 4898.3;testis: 3242.2" "Group enriched" "Detected in many" 11 "Leydig cells: 38051.3;Peritubular cells: 65156.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 27 "plasmacytoid DC: 1386.8" "Lineage enriched" "Detected in many" 27 "dendritic cells: 1386.8" "Group enriched" "Detected in some" 6 "HHSteC: 518.7;HSkMC: 252.0" "HPA004938, CAB009916, HPA067456" Uncertain "Secreted to blood" NA NA 2500000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "CAB009916: AB_2174617, HPA004938: AB_1855745, HPA067456: " "unprognostic (2.79e-2)" "unprognostic (3.96e-3)" "unprognostic (9.70e-2)" "unprognostic (5.71e-3)" "unprognostic (6.50e-2)" "unprognostic (1.43e-3)" "unprognostic (2.85e-1)" "unprognostic (2.01e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.19e-7)" "unprognostic (8.49e-3)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (3.21e-2)" 391.1 297.1 1849.2 247.1 2423.8 9.9 121.1 2440.1 2559.6 1675.5 1508.4 84.8 31.5 320.4 735.9 172.5 492.1 396.7 4898.3 1760.9 2034.8 466.5 80.2 607.8 824.1 2339.4 2228.2 66.8 113.2 9.1 398.4 227.8 2318.0 727.0 17.7 146.1 97.8 813.1 108.3 164.9 205.9 99.7 1999.6 317.5 93.0 3242.2 2264.9 127.4 55.1 60.0 306.0 230.3 1181.0 2580.3 0.1 0.0 0.1 0.0 5.4 16.7 8.8 0.3 0.0 0.0 0.0 0.0 0.2 0.6 4.0 24.0 0.0 0.8 0.6 0.2 0.0 0.0 0.0 0.0 1.4 0.3 518.7 0.3 1.3 252.0 0.1 0.0 0.0 1.8 0.0 0.0 0.6 1.0 0.2 0.0 0.0 6.6 0.9 8.2 0.0 0.1 0.2 1.6 0.0 0.0 1.6 2.0 0.0 0.6 0.0 0.1 0.6 68.3 0.7 0.2 0.2 2.1 0.1 0.3 0.0 0.1 3.9 0.0 0.9 0.0 0.3 0.4 50.5 1.0 3.4 0.3 4.3 6.3 1.8 0.2 0.9 9.9 2.3 3.8 0.2 1386.8 1.4 11.2 1849.2 2423.8 2440.1 2559.6 1760.9 2034.8 2339.4 2228.2 2318.0 1999.6 2264.9 2580.3 29.3 0.0 0.6 665.0 1.5 70.4 3.2 0.1 5.7 46.8 6.6 14.7 333.6 8.6 0.1 138.0 52.1 14.4 1863.6 0.2 68.4 0.3 215.9 29.7 1156.5 167.8 0.0 13.5 4.0 0.0 55.0 1584.0 1.1 20.1 1.3 0.3 46.1 1.6 57.3 21.9 12.8 0.0 0.0 3.4 161.8 1230.9 38051.3 57.0 209.9 176.1 4.6 4625.8 583.9 63.3 850.4 1.7 0.0 65156.8 6.0 20.7 0.0 1.1 0.0 130.3 164.3 787.4 124.8 130.7 111.1 12.0 80.1 35.4 61.3 0.1 0.0 14.5 PTGES "MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12" ENSG00000148344 "Prostaglandin E synthase" O14684 9 129738331-129753042 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 84.2;urinary bladder: 78.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 101.2;Cytotrophoblasts: 146.0;Extravillous trophoblasts: 293.1;Syncytiotrophoblasts: 276.2" "Cancer enhanced" "Detected in all" "urothelial cancer: 69.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 28.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "ASC diff: 147.7;BEWO: 162.7;GAMG: 292.8;HaCaT: 216.3;SK-BR-3: 157.6;U-2197: 404.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045064 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA045064: AB_10795889" "unprognostic (2.92e-3)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (2.54e-2)" "unprognostic (1.94e-3)" "unprognostic (1.25e-1)" "unprognostic (5.38e-3)" "unprognostic (1.24e-3)" "unprognostic (2.92e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.22e-1)" "unprognostic (4.66e-2)" "unprognostic (9.78e-3)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (5.20e-2)" 36.7 1.4 4.1 13.9 3.6 7.8 25.5 3.9 4.5 26.1 3.5 9.2 2.8 3.7 19.0 17.8 5.4 9.0 8.5 4.5 5.1 8.1 0.7 7.8 7.6 6.1 5.8 2.2 1.6 42.1 1.9 58.4 7.1 13.7 4.2 0.0 30.8 84.2 1.3 42.3 9.1 4.1 4.1 2.5 7.1 16.9 4.7 4.2 3.7 1.1 30.7 78.6 20.0 3.5 1.5 94.9 0.1 46.6 147.7 51.9 162.7 7.4 64.2 1.1 1.7 5.6 71.7 0.1 2.7 18.0 292.8 216.3 0.7 7.2 0.6 0.3 0.5 0.0 62.5 0.4 3.5 0.0 0.0 30.9 49.0 0.9 0.3 1.4 0.0 0.9 0.0 0.1 0.7 1.7 0.2 0.0 1.2 46.7 8.2 0.2 0.0 0.3 5.3 102.2 0.8 3.6 87.1 157.6 0.8 6.3 83.3 0.0 0.5 0.1 0.4 404.8 0.0 0.0 0.0 0.0 78.8 0.1 0.7 28.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 4.0 0.0 0.0 0.3 4.1 3.6 3.9 4.5 4.5 5.1 6.1 5.8 7.1 4.1 4.7 3.5 3.4 0.0 0.0 0.3 0.3 17.8 8.9 101.2 10.8 0.0 29.7 19.7 0.1 0.0 53.2 3.7 0.0 146.0 0.6 0.0 1.9 13.4 0.6 1.6 2.3 4.0 7.3 0.0 1.0 1.1 293.1 70.7 0.0 5.0 1.3 61.5 0.0 0.0 17.5 0.0 2.8 6.6 30.5 0.0 21.6 0.4 0.3 13.2 14.2 7.5 7.2 0.0 0.0 0.0 0.2 8.1 0.2 0.0 0.3 8.2 0.3 0.5 6.7 0.0 0.0 0.8 13.5 0.3 0.0 5.5 43.0 276.2 0.8 0.2 0.4 49.2 PTGES2 "C9orf15, FLJ14038" ENSG00000148334 "Prostaglandin E synthase 2" Q9H7Z7 9 128120693-128128462 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 700.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020631, HPA020733" Approved Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA020631: AB_1855887, HPA020733: AB_2670508" "unprognostic (1.23e-1)" "unprognostic (1.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (1.68e-2)" "unprognostic (5.13e-3)" "unprognostic (2.56e-1)" "unprognostic (1.57e-1)" "unprognostic (7.10e-2)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.83e-7)" "unprognostic (2.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" 18.1 49.8 31.6 15.6 33.9 6.5 16.0 29.1 45.8 18.1 32.4 30.6 27.5 21.6 4.0 35.3 17.6 11.4 95.0 35.6 33.0 36.4 37.7 14.8 17.6 31.5 31.5 16.1 37.6 35.2 41.4 9.7 32.1 24.6 9.2 10.0 26.1 16.8 117.9 20.9 23.8 7.5 27.3 21.1 29.6 14.5 31.5 11.9 23.5 78.7 9.7 22.3 22.0 31.7 46.1 114.0 15.5 54.4 13.5 12.8 47.9 30.7 20.6 48.6 24.9 86.9 75.6 43.5 45.7 15.9 36.9 108.8 22.5 47.1 6.5 28.3 62.3 21.0 92.7 79.5 41.0 42.1 39.5 18.6 32.3 39.5 26.9 14.2 31.6 47.8 50.2 26.4 16.7 130.0 56.9 75.6 42.7 58.7 113.9 39.6 26.5 111.6 32.8 33.1 69.1 45.6 47.3 86.3 34.2 6.7 78.7 23.5 34.0 46.3 50.2 62.8 63.1 48.9 25.5 38.3 39.1 33.2 44.5 1.4 3.3 0.7 3.1 3.7 3.8 3.8 2.2 3.5 4.3 2.7 2.4 3.0 0.6 2.7 1.8 5.8 3.1 1.9 31.6 33.9 29.1 45.8 35.6 33.0 31.5 31.5 32.1 27.3 31.5 31.7 18.8 16.0 6.4 10.4 32.0 22.9 38.1 32.7 25.0 37.8 34.2 36.3 700.2 51.5 25.9 23.9 20.9 82.1 30.8 86.1 146.8 74.6 2.1 12.7 20.9 29.4 45.1 13.2 15.5 51.8 62.1 32.7 46.4 17.3 14.7 31.9 13.9 37.8 57.6 37.0 15.8 62.2 46.8 25.3 43.6 4.8 30.7 30.8 56.9 3.7 105.7 21.9 38.1 12.1 7.2 57.6 60.4 21.8 45.4 68.0 93.4 99.3 9.3 44.8 19.7 17.8 37.2 3.6 45.6 48.3 24.6 66.6 25.6 84.1 105.5 52.9 PTGES3 "cPGES, p23, TEBP" ENSG00000110958 "Prostaglandin E synthase 3" Q15185 12 56663341-56688408 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034319, HPA038672, HPA038673" Enhanced Approved Nucleoplasm,Cytosol NA NA 660000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 65: Brain - Ion transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "CAB034319: AB_2175206, HPA038672: AB_10697395, HPA038673: AB_10670786" "prognostic unfavorable (2.15e-5)" "unprognostic (2.60e-1)" "unprognostic (8.67e-3)" "unprognostic (7.07e-2)" "unprognostic (2.24e-1)" "unprognostic (2.96e-3)" "prognostic unfavorable (4.44e-6)" "unprognostic (4.33e-3)" "unprognostic (3.64e-2)" "prognostic favorable (4.36e-4)" "unprognostic (2.73e-2)" "unprognostic (2.31e-2)" "unprognostic (3.05e-3)" "unprognostic (1.01e-1)" "unprognostic (2.17e-1)" "unprognostic (2.28e-1)" "unprognostic (2.07e-1)" 141.7 128.0 198.0 137.2 210.0 150.2 171.2 217.0 454.6 168.2 185.5 169.9 151.7 172.9 159.0 161.3 217.6 114.9 122.8 195.5 215.6 180.5 218.6 133.9 157.2 214.9 213.0 250.0 121.9 133.7 111.7 164.9 218.5 141.6 172.8 118.0 124.0 147.6 208.6 123.5 155.4 138.8 213.0 125.0 117.1 135.0 204.3 167.2 162.3 158.5 185.0 158.7 145.8 278.0 616.6 528.8 416.5 249.8 300.2 270.3 634.3 392.8 298.5 494.5 366.9 452.5 629.6 676.0 588.5 338.3 331.7 385.4 790.0 514.2 621.8 509.8 529.8 529.7 309.5 524.4 219.4 637.9 367.2 197.0 367.3 375.1 450.3 468.5 518.1 425.7 866.0 628.2 490.4 385.3 636.5 602.1 714.7 538.3 609.3 549.2 392.3 914.4 436.8 473.2 538.4 313.8 401.7 570.1 355.8 546.5 658.3 526.9 314.0 294.7 341.8 358.3 552.8 262.8 777.5 540.4 321.1 516.7 543.8 141.1 166.1 107.1 130.9 261.6 172.3 172.3 170.6 156.7 160.2 127.0 167.3 147.7 64.7 132.2 346.2 135.3 191.6 316.1 198.0 210.0 217.0 454.6 195.5 215.6 214.9 213.0 218.5 213.0 204.3 278.0 265.8 179.5 137.1 39.5 251.0 386.6 826.7 248.5 272.6 128.3 208.5 197.1 166.0 178.7 161.4 189.4 77.2 457.2 245.6 246.5 373.7 310.4 42.5 493.7 221.5 242.1 261.3 452.0 43.4 214.8 676.3 268.7 143.2 291.3 234.2 224.5 188.8 187.0 349.9 112.7 41.3 295.9 201.4 209.5 363.6 107.9 238.9 261.7 282.8 47.8 283.3 244.1 178.2 38.7 71.4 220.8 207.1 213.3 299.8 657.6 218.9 343.8 345.5 128.0 144.7 185.1 337.7 558.4 348.4 350.4 377.6 566.0 359.3 219.0 358.9 556.3 PTGIS "CYP8A1, PGIS" ENSG00000124212 "Prostaglandin I2 synthase" Q16647 20 49503874-49568137 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 80.7;urinary bladder: 81.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 28.1;Fibroblasts: 70.8;Hepatic stellate cells: 117.8;Leydig cells: 26.8;Peritubular cells: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 45.1;ASC TERT1: 45.2;U-2197: 143.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009517, HPA014193, HPA052244" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB009517: AB_2173209, HPA014193: AB_1855746, HPA052244: AB_2732574" "unprognostic (7.68e-2)" "unprognostic (1.90e-1)" "unprognostic (5.09e-3)" "unprognostic (1.38e-2)" "unprognostic (1.80e-2)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (1.29e-2)" "unprognostic (1.25e-1)" "unprognostic (4.02e-2)" "unprognostic (2.45e-2)" "unprognostic (5.22e-2)" "prognostic unfavorable (4.74e-8)" "unprognostic (2.29e-2)" "unprognostic (7.61e-2)" "unprognostic (4.89e-3)" "prognostic unfavorable (9.99e-5)" 43.2 4.7 0.7 9.0 2.5 0.3 24.0 0.3 1.9 29.5 1.8 38.9 3.2 79.0 16.1 16.5 80.7 31.3 40.4 0.5 0.8 4.0 6.0 18.2 0.7 0.6 0.4 38.1 2.5 0.3 0.9 1.1 0.4 22.2 6.6 0.2 7.6 8.3 4.0 7.2 10.5 40.5 0.6 0.5 17.9 5.1 1.0 0.3 7.8 2.4 0.8 81.7 18.2 0.6 0.0 0.1 1.9 0.1 45.1 45.2 0.5 1.0 5.7 0.2 0.0 0.0 0.0 0.1 18.4 13.7 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.1 3.3 0.0 0.6 0.0 15.1 0.7 0.0 0.0 0.1 0.1 0.0 0.1 0.2 8.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.4 0.1 0.2 0.0 8.2 0.1 0.0 0.0 0.8 2.4 143.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.7 2.5 0.3 1.9 0.5 0.8 0.6 0.4 0.4 0.6 1.0 0.6 5.3 3.2 2.7 0.0 0.0 3.7 0.7 0.0 0.0 1.1 2.2 1.3 5.0 2.8 1.9 3.7 0.0 0.3 0.3 0.0 0.0 0.6 1.8 0.0 0.9 28.1 0.0 2.7 2.7 0.0 0.2 70.8 1.5 0.1 0.0 25.0 117.8 1.0 0.3 0.0 2.4 0.0 0.0 3.1 6.7 3.3 26.8 1.0 1.8 6.5 0.1 0.4 0.0 1.0 0.2 1.2 0.0 104.9 0.3 0.4 0.0 0.2 2.2 4.5 0.0 7.9 3.5 0.7 1.4 0.5 4.8 0.3 1.0 0.5 0.0 0.6 PTPA "PPP2R4, PR53" ENSG00000119383 "Protein phosphatase 2 phosphatase activator" Q15257 9 129110950-129148946 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 51.9;Collecting duct cells: 53.3;Cytotrophoblasts: 49.5;Distal tubular cells: 54.8;Ductal cells: 70.3;Exocrine glandular cells: 62.3;Hofbauer cells: 53.9;Pancreatic endocrine cells: 61.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005695, CAB022068, CAB035999" Approved Enhanced Nucleoplasm,Cytosol NA NA 4300000 "Cluster 39: Non-specific - mRNA processing" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "CAB022068: , CAB035999: , HPA005695: AB_1855658" "unprognostic (4.97e-2)" "unprognostic (1.70e-2)" "unprognostic (1.13e-2)" "prognostic favorable (6.50e-5)" "unprognostic (1.56e-2)" "unprognostic (1.15e-1)" "unprognostic (6.65e-2)" "unprognostic (6.44e-3)" "unprognostic (2.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.01e-2)" "unprognostic (1.92e-2)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" 47.2 118.0 157.8 56.2 154.0 52.9 60.9 136.2 185.0 73.5 124.6 105.2 49.6 87.4 55.8 116.8 77.3 49.3 176.7 158.5 141.6 125.5 154.2 72.6 49.9 151.3 148.8 63.8 70.4 146.7 73.1 49.8 147.6 119.0 51.3 43.4 97.1 86.8 340.8 73.7 57.1 92.1 143.2 82.8 83.5 124.5 162.7 59.1 75.3 206.2 54.9 71.1 62.2 148.5 108.9 183.9 111.0 219.9 74.4 94.5 118.3 115.5 120.2 144.8 100.1 103.4 135.4 113.9 83.3 187.3 173.1 184.1 110.9 138.2 100.6 198.6 68.1 64.6 193.6 101.7 229.1 113.1 147.2 114.6 133.1 109.8 101.8 230.9 146.5 120.3 102.0 124.7 117.1 293.8 103.0 76.6 186.8 301.0 193.0 108.3 93.7 216.2 159.0 119.8 120.6 86.9 220.4 237.3 147.3 99.4 253.4 55.0 101.7 127.6 113.8 129.9 165.2 114.9 284.1 96.8 153.2 79.1 180.7 7.6 19.2 9.8 20.8 18.4 19.9 10.8 15.8 18.5 23.0 13.4 13.8 13.9 6.1 20.4 18.3 16.4 16.9 20.4 157.8 154.0 136.2 185.0 158.5 141.6 151.3 148.8 147.6 143.2 162.7 148.5 19.8 3.2 8.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 51.9 38.6 0.0 0.0 3.1 53.3 0.0 49.5 9.2 0.0 54.8 70.3 0.0 33.7 21.8 19.0 0.0 0.0 0.0 62.3 44.2 12.2 0.0 32.9 8.8 24.8 0.0 0.0 53.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 21.7 0.0 0.0 0.0 0.0 61.8 0.0 0.0 0.9 0.0 0.0 41.9 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 37.9 4.0 31.8 0.0 0.0 PUS1 ENSG00000177192 "Pseudouridine synthase 1" Q9Y606 12 131929200-131945896 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" Isomerase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051636, HPA057593" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA051636: AB_2681560, HPA057593: AB_2683479" "unprognostic (2.72e-1)" "unprognostic (9.13e-2)" "unprognostic (1.81e-1)" "unprognostic (2.69e-2)" "unprognostic (8.12e-3)" "unprognostic (8.07e-2)" "unprognostic (4.57e-3)" "unprognostic (7.34e-2)" "unprognostic (1.01e-1)" "unprognostic (3.34e-1)" "unprognostic (2.06e-1)" "unprognostic (5.30e-2)" "prognostic unfavorable (3.49e-8)" "unprognostic (1.80e-3)" "unprognostic (8.06e-2)" "unprognostic (8.59e-2)" "unprognostic (1.56e-2)" 12.5 14.9 10.1 14.9 8.4 23.0 10.4 8.2 10.2 9.7 7.6 11.9 9.7 12.5 14.0 16.5 11.2 7.1 8.7 8.9 5.9 13.0 21.6 9.0 18.5 7.1 5.1 8.6 14.8 5.4 8.7 6.4 6.2 10.9 7.9 5.0 9.3 6.8 14.2 14.4 14.0 7.4 4.4 15.8 12.7 13.0 6.9 8.6 9.5 4.8 10.6 14.2 10.7 9.2 45.3 58.1 13.7 24.0 13.0 21.5 82.2 34.5 14.2 25.4 16.3 64.5 28.7 53.2 38.3 18.6 19.9 56.0 44.4 32.2 16.3 24.0 90.6 54.0 30.9 56.9 34.0 93.5 47.4 21.7 25.6 28.9 24.8 12.3 25.0 36.8 68.0 15.6 14.9 77.9 61.9 83.4 71.5 36.7 87.3 57.8 19.2 55.4 20.8 61.7 37.5 20.8 28.6 38.9 32.5 13.1 42.5 99.3 22.7 20.2 43.3 43.1 50.0 43.5 35.5 64.5 20.7 73.6 28.4 1.0 1.3 0.2 2.0 1.0 1.5 4.6 1.7 2.1 1.1 4.2 2.4 1.3 1.1 5.6 0.9 3.0 1.8 0.9 10.1 8.4 8.2 10.2 8.9 5.9 7.1 5.1 6.2 4.4 6.9 9.2 7.0 0.0 6.1 9.8 10.7 29.6 22.3 8.4 6.2 6.2 10.7 10.5 5.3 8.6 6.2 5.5 22.9 13.9 11.7 10.9 5.9 12.3 0.9 6.6 10.1 11.1 14.4 13.2 11.9 9.6 19.1 8.3 15.3 7.7 16.5 11.7 6.1 12.9 15.2 0.0 8.4 20.1 10.2 7.3 8.1 3.0 7.8 7.2 7.2 9.4 8.8 4.4 6.2 5.0 7.1 16.3 6.9 9.4 8.8 35.4 4.0 13.7 4.9 10.0 6.6 15.9 9.3 18.5 19.7 14.7 22.7 8.6 9.5 14.3 18.8 21.4 PUS10 "CCDC139, FLJ32312" ENSG00000162927 "Pseudouridine synthase 10" Q3MIT2 2 60940222-61018259 "Enzymes, Predicted intracellular proteins" "tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044736, HPA049582" Approved Approved "Nucleoplasm,Nuclear bodies,Mitochondria" No No "Cluster 18: Basophils - Vesicular transport" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nuclear bodies, Mitochondria" "HPA044736: AB_2679066, HPA049582: AB_2680824" "unprognostic (1.90e-3)" "unprognostic (1.35e-1)" "unprognostic (3.49e-2)" "unprognostic (2.44e-4)" "unprognostic (1.77e-1)" "unprognostic (1.86e-2)" "unprognostic (1.25e-1)" "unprognostic (1.72e-2)" "unprognostic (2.90e-2)" "unprognostic (8.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.45e-1)" "unprognostic (1.16e-4)" "unprognostic (1.07e-1)" "unprognostic (6.60e-2)" "unprognostic (9.45e-2)" "unprognostic (1.15e-3)" 3.6 3.7 2.7 4.1 2.7 5.1 5.4 2.9 3.4 3.0 3.2 3.6 7.5 3.3 6.4 2.7 3.7 4.1 3.7 2.7 2.5 4.8 15.0 4.9 6.8 2.7 2.6 4.8 4.0 3.9 2.9 3.2 3.0 4.8 4.4 3.9 3.8 2.6 3.1 4.9 9.3 2.7 2.9 4.8 3.4 4.5 2.9 4.5 6.9 1.8 6.8 2.6 1.6 3.6 3.2 1.7 4.9 8.4 4.1 4.6 5.3 6.1 5.5 6.0 5.6 4.8 4.4 12.8 6.3 3.4 5.4 4.2 5.7 4.9 7.4 10.0 2.9 9.0 2.5 15.9 7.6 10.6 5.8 5.3 6.0 4.2 9.4 7.7 7.9 9.1 9.2 6.4 4.6 2.7 8.0 8.7 4.4 3.0 3.5 7.7 6.6 4.7 4.3 6.3 2.8 3.9 5.0 9.7 9.9 3.5 3.4 6.3 5.9 5.7 4.6 3.9 4.7 8.1 3.8 23.6 5.0 6.8 6.5 9.1 1.2 1.1 2.3 1.3 2.5 3.0 1.4 1.6 0.9 1.7 1.7 1.9 2.3 3.1 4.8 3.0 1.0 1.1 2.7 2.7 2.9 3.4 2.7 2.5 2.7 2.6 3.0 2.9 2.9 3.6 6.6 0.0 14.3 20.5 6.8 2.4 3.5 3.3 1.8 6.6 5.9 2.8 5.1 1.5 4.3 3.7 0.0 7.0 8.1 11.9 7.9 3.7 1.6 6.2 4.3 5.8 1.2 5.9 28.3 5.1 4.7 3.1 5.1 8.5 0.0 9.9 4.6 16.3 5.8 1.7 21.7 2.5 4.1 5.7 2.1 1.8 3.1 4.6 1.8 14.0 9.0 7.0 7.2 19.1 24.4 3.5 3.0 1.5 4.6 3.8 26.7 6.3 7.7 7.1 6.6 3.1 3.0 13.9 13.4 3.9 2.3 12.4 6.6 8.2 4.5 10.6 PUS3 FKSG32 ENSG00000110060 "Pseudouridine synthase 3" Q9BZE2 11 125893485-125903221 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" Isomerase "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038040, HPA063802" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "HPA038040: AB_10697092, HPA063802: AB_2685126" "unprognostic (5.89e-2)" "unprognostic (7.24e-2)" "unprognostic (1.29e-1)" "unprognostic (4.37e-3)" "unprognostic (4.59e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (7.67e-2)" "unprognostic (1.77e-1)" "unprognostic (8.92e-3)" "unprognostic (4.47e-3)" "unprognostic (3.37e-2)" "unprognostic (1.06e-1)" "unprognostic (2.08e-3)" "unprognostic (9.95e-2)" "unprognostic (1.32e-1)" "unprognostic (1.13e-1)" "unprognostic (2.44e-1)" 8.3 8.4 7.1 8.2 7.8 3.3 9.4 8.4 11.6 7.7 6.7 8.5 10.9 7.8 9.7 9.0 7.4 6.5 7.1 7.1 8.7 9.0 33.2 6.1 9.2 7.8 7.8 7.3 17.8 7.0 8.5 6.7 7.3 8.7 7.9 8.4 7.7 5.4 15.0 9.5 6.8 9.7 7.0 7.6 10.1 7.2 8.5 11.0 9.3 15.2 10.5 10.1 6.3 7.6 6.5 7.9 23.2 24.9 24.3 29.7 11.0 21.1 17.0 11.6 13.2 24.0 23.2 31.4 33.3 9.2 17.1 22.5 37.6 19.7 11.5 28.2 18.2 31.2 9.5 18.6 24.6 20.5 9.2 23.1 23.4 13.7 29.8 16.2 21.0 23.5 34.0 16.1 13.0 4.0 23.7 23.6 19.8 47.0 15.8 4.8 20.5 18.4 20.3 9.5 27.1 25.7 13.1 21.4 11.7 16.5 43.2 13.8 15.3 24.0 10.1 11.9 17.3 12.4 20.1 33.6 6.7 31.9 17.1 14.2 10.5 9.9 13.4 10.8 15.3 13.3 13.1 12.8 9.2 14.8 17.0 16.0 4.2 14.9 14.0 8.0 15.0 8.3 7.1 7.8 8.4 11.6 7.1 8.7 7.8 7.8 7.3 7.0 8.5 7.6 8.5 9.6 11.5 3.6 9.5 12.9 12.2 10.6 8.0 9.3 7.3 9.4 5.4 11.5 13.6 5.5 29.2 9.7 7.4 3.6 5.9 17.8 7.7 4.4 8.9 10.5 4.8 14.5 2.9 27.2 12.7 6.1 9.2 4.4 12.7 6.1 10.4 33.0 8.2 5.0 3.4 4.6 10.2 5.0 2.9 6.3 7.8 5.5 1.8 1.9 9.9 9.8 6.2 2.5 3.8 15.0 3.9 7.9 6.7 9.1 10.2 16.9 6.2 10.9 6.6 9.9 10.1 7.8 7.2 6.7 11.8 14.0 7.9 12.8 6.5 10.9 RENBP "RBP, RNBP" ENSG00000102032 "Renin binding protein" P51606 X 153935269-153944687 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 43.0;lymphoid tissue: 67.0" "Cell type enhanced" "Detected in many" "granulocytes: 127.7;Hofbauer cells: 183.4;Kupffer cells: 70.7;Proximal tubular cells: 204.2" "Cancer enhanced" "Detected in all" "melanoma: 57.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "granulocytes: 2.7;monocytes: 1.6" "Cell line enhanced" "Detected in many" "EFO-21: 35.5;HMC-1: 121.4;SK-MEL-30: 86.4;U-266/84: 74.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000428, HPA000522" Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000428: AB_1079799, HPA000522: AB_1079798" "unprognostic (3.08e-1)" "prognostic favorable (3.95e-4)" "unprognostic (1.12e-2)" "unprognostic (3.29e-1)" "unprognostic (8.83e-3)" "unprognostic (1.85e-1)" "unprognostic (5.22e-2)" "unprognostic (1.02e-2)" "unprognostic (2.18e-2)" "unprognostic (1.15e-1)" "unprognostic (6.47e-3)" "unprognostic (1.99e-1)" "prognostic favorable (3.08e-5)" "unprognostic (2.39e-2)" "unprognostic (6.57e-2)" "unprognostic (4.25e-2)" "unprognostic (8.51e-2)" 22.2 19.2 14.6 13.5 18.2 10.9 11.1 16.0 20.6 5.0 12.3 13.8 8.4 3.9 2.5 2.9 5.6 6.2 11.5 14.6 18.8 43.0 5.3 24.6 16.5 18.4 19.8 1.7 1.8 2.1 6.0 10.3 18.0 3.8 4.2 2.2 5.8 2.0 2.2 9.7 13.9 4.7 15.2 67.0 5.9 1.2 19.4 6.2 5.4 0.1 6.3 6.2 4.5 19.6 0.0 0.0 3.3 0.1 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 35.5 0.0 0.1 0.0 7.1 0.0 0.0 0.0 1.5 28.2 0.0 2.3 20.4 0.0 121.4 0.8 0.0 0.0 0.0 0.0 0.0 1.0 8.2 10.3 0.0 0.6 7.5 0.3 0.4 0.3 0.0 13.6 0.0 0.1 0.0 0.0 0.1 2.0 0.0 0.0 86.4 3.0 0.3 9.9 1.3 0.0 0.8 0.0 0.1 12.5 74.8 5.0 2.5 13.3 9.8 1.7 0.9 2.7 0.1 0.7 0.1 0.4 0.0 0.0 0.1 0.2 0.4 0.2 2.0 0.1 1.6 0.3 0.0 0.5 14.6 18.2 16.0 20.6 14.6 18.8 18.4 19.8 18.0 15.2 19.4 19.6 1.9 0.0 2.2 7.2 8.0 4.7 1.3 0.3 0.6 2.4 0.4 0.6 1.0 2.8 0.4 9.2 0.0 1.3 2.6 0.4 37.2 1.4 0.1 0.1 0.5 10.7 1.8 3.0 0.2 0.4 6.0 4.5 0.0 0.3 127.7 1.3 52.1 0.8 183.4 15.2 1.7 1.0 0.0 70.7 13.3 0.4 0.3 49.2 28.4 6.5 40.7 10.7 8.2 0.5 6.2 0.5 5.3 0.4 4.0 1.4 12.3 204.2 0.2 0.8 13.1 2.2 4.9 0.1 1.4 0.4 2.0 2.9 7.5 0.7 0.7 0.6 RPE ENSG00000197713 Ribulose-5-phosphate-3-epimerase Q96AT9 2 210002565-210022260 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036498, HPA036499" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 130000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "Nucleoplasm, Plasma membrane" "HPA036498: AB_2675157, HPA036499: AB_10670109" "unprognostic (5.07e-2)" "unprognostic (8.15e-2)" "unprognostic (3.06e-1)" "unprognostic (2.34e-3)" "unprognostic (2.00e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (1.42e-6)" "unprognostic (1.59e-3)" "unprognostic (1.69e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (2.33e-2)" "unprognostic (2.55e-2)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "unprognostic (2.89e-1)" "unprognostic (5.84e-2)" 21.9 27.6 15.9 20.1 20.0 19.4 25.4 18.3 21.7 19.7 11.9 24.0 21.8 22.6 22.3 29.1 21.0 19.8 14.5 16.2 14.7 30.0 27.4 17.9 25.1 11.0 13.3 25.4 15.1 21.0 17.2 29.4 12.8 22.5 31.8 17.8 20.6 31.1 11.0 19.7 19.8 29.3 14.6 19.2 24.2 15.3 16.5 22.9 29.5 27.4 29.4 27.4 17.4 23.1 62.4 81.0 47.5 47.9 71.3 68.0 85.4 80.2 60.9 67.9 93.1 118.7 92.1 39.9 50.6 58.8 104.1 59.9 69.7 81.9 103.3 49.7 47.8 78.2 112.3 112.3 98.8 80.7 56.1 51.7 75.4 83.2 107.5 60.2 94.8 39.1 79.7 57.2 55.5 106.7 43.5 63.5 68.2 121.4 59.8 52.4 58.4 56.7 78.6 94.7 56.6 31.4 70.2 63.7 52.3 85.6 54.4 85.2 80.0 96.7 66.9 47.5 73.8 31.9 49.5 88.6 69.6 76.0 62.5 20.2 40.2 19.1 23.1 51.0 19.8 20.2 17.7 21.7 69.5 21.6 23.4 21.0 3.7 77.2 34.8 25.4 26.7 28.8 15.9 20.0 18.3 21.7 16.2 14.7 11.0 13.3 12.8 14.6 16.5 23.1 14.9 6.4 7.5 14.4 13.1 16.6 15.2 21.6 13.1 13.2 13.2 10.3 6.2 10.0 20.1 18.4 20.9 35.4 18.1 14.0 31.3 24.5 10.7 13.5 17.4 14.3 10.2 17.2 61.9 17.5 42.8 17.4 14.3 11.2 6.3 18.1 18.2 17.5 37.0 10.1 44.7 14.6 14.2 19.4 45.8 11.8 11.1 17.2 14.2 15.0 19.7 8.9 26.8 27.2 39.2 19.4 11.6 14.7 12.2 19.9 14.2 48.6 15.9 12.7 6.6 11.1 16.1 14.7 17.4 20.1 20.3 25.6 10.5 24.8 21.3 14.8 RPE65 "BCO3, LCA2, rd12, RP20" ENSG00000116745 "Retinoid isomerohydrolase RPE65" Q16518 1 68428822-68449954 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Hydrolase, Isomerase" "Disease variant, FDA approved drug targets, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.2;choroid plexus: 4.5;retina: 8.4;seminal vesicle: 4.5" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 10.4;Rod photoreceptor cells: 17.8" "Group enriched" "Detected in some" 10 "glioma: 5.8;head and neck cancer: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.4;PC-3: 5.6;U-2 OS: 1.3" "Group enriched" "Detected in many" 4 "amygdala: 3.2;basal ganglia: 2.5;cerebral cortex: 3.9;hippocampal formation: 2.5" "Low region specificity" "Detected in many" NA NA "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.59e-1)" "unprognostic (1.88e-1)" "unprognostic (3.15e-1)" "prognostic favorable (9.75e-4)" "unprognostic (4.55e-2)" "unprognostic (5.91e-2)" "unprognostic (6.59e-4)" "unprognostic (2.98e-2)" "unprognostic (1.57e-1)" "unprognostic (8.24e-2)" "unprognostic (3.21e-4)" "unprognostic (2.11e-1)" "unprognostic (2.05e-1)" "unprognostic (3.48e-2)" "unprognostic (8.40e-3)" 0.0 0.0 1.5 0.0 0.8 0.0 0.4 0.5 0.5 0.2 4.5 0.1 0.2 0.6 0.1 0.3 0.3 0.1 0.0 0.7 3.0 0.0 0.0 0.0 0.0 1.1 5.2 0.0 0.0 0.0 0.0 0.0 2.0 1.8 0.1 8.4 0.1 4.5 0.0 0.0 0.0 0.2 1.7 0.1 0.3 0.1 4.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.8 0.5 0.5 0.7 3.0 1.1 5.2 2.0 1.7 4.0 1.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.1 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 1.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 17.8 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RPEL1 ENSG00000235376 "Ribulose-5-phosphate-3-epimerase like 1" Q2QD12 10 103245887-103248016 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.1;Cone photoreceptor cells: 8.4;Ionocytes: 2.0;Rod photoreceptor cells: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036498, HPA036499" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Nucleoplasm, Plasma membrane" "HPA036498: AB_2675157, HPA036499: AB_10670109" "unprognostic (7.52e-2)" "unprognostic (1.69e-1)" "unprognostic (4.78e-2)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (1.83e-1)" "unprognostic (6.01e-2)" "unprognostic (1.15e-1)" "unprognostic (8.91e-2)" "unprognostic (6.59e-2)" "unprognostic (4.34e-1)" "unprognostic (1.14e-1)" "unprognostic (5.69e-2)" "unprognostic (1.62e-1)" "unprognostic (6.72e-2)" "unprognostic (5.06e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.0 3.1 0.0 0.0 1.9 0.0 0.7 0.0 8.4 0.3 1.3 0.5 0.0 0.5 0.1 0.1 0.0 0.3 1.8 0.0 0.6 0.2 0.5 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.6 0.5 2.0 0.0 1.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.5 0.1 0.2 4.4 0.0 0.0 0.4 0.1 0.3 0.0 0.3 0.4 0.1 0.0 0.7 0.0 RPIA ENSG00000153574 "Ribose 5-phosphate isomerase A" P49247 2 88691673-88750929 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.6" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 234.3;Erythroid cells: 167.9;Syncytiotrophoblasts: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042620, HPA057954" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 2500000 "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles, Plasma membrane" "HPA042620: AB_10793980, HPA057954: AB_2683563" "unprognostic (3.35e-2)" "unprognostic (1.35e-2)" "unprognostic (6.96e-2)" "unprognostic (9.24e-2)" "unprognostic (4.31e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (8.70e-2)" "unprognostic (8.82e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (8.53e-6)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-2)" "unprognostic (8.79e-3)" 17.2 11.0 7.4 19.6 7.6 89.6 16.0 8.3 8.9 13.4 8.0 22.7 22.1 13.2 9.5 24.1 14.6 11.7 16.0 7.3 8.2 10.6 7.8 12.2 28.0 7.8 7.5 13.7 17.9 7.4 8.2 33.8 7.5 8.9 23.0 4.1 15.9 8.1 29.9 11.9 18.9 12.5 7.8 19.2 18.9 9.6 8.0 40.4 9.7 17.1 32.4 16.5 12.5 7.9 29.7 17.0 33.7 26.9 23.4 23.9 73.8 16.1 15.1 26.1 17.8 61.1 38.2 150.1 34.3 18.7 35.8 17.7 42.4 13.5 40.9 71.9 55.3 60.2 11.0 60.7 23.7 111.5 42.4 22.1 11.2 23.3 35.9 13.0 37.4 78.7 65.7 25.3 24.8 46.5 123.4 97.2 30.7 97.6 27.7 63.5 40.1 36.8 21.7 47.1 24.0 27.4 19.4 24.8 39.3 18.3 13.5 45.3 21.4 15.5 40.7 51.2 46.7 19.7 17.2 149.3 15.9 99.4 22.5 10.6 16.0 36.4 16.9 16.7 21.4 31.4 23.5 25.1 22.7 23.5 33.4 27.8 3.9 21.9 21.9 10.9 22.0 20.6 7.4 7.6 8.3 8.9 7.3 8.2 7.8 7.5 7.5 7.8 8.0 7.9 38.9 12.8 13.2 4.6 43.2 37.3 21.3 31.2 21.6 8.7 22.2 18.2 13.7 14.3 22.7 20.2 2.1 234.3 37.1 20.6 9.8 21.7 8.1 28.0 23.3 35.0 19.2 167.9 13.3 34.2 98.9 23.5 31.1 43.2 21.6 30.7 24.3 7.1 43.8 13.5 15.7 26.9 26.4 23.1 33.9 4.0 19.9 23.7 40.9 11.2 32.4 5.2 60.8 13.6 13.3 22.8 28.1 18.8 35.8 41.7 20.6 18.7 10.1 4.8 19.7 19.8 18.0 28.4 33.4 37.6 40.9 225.6 38.8 37.8 58.5 43.7 SPAST "ADPSP, FSP2, KIAA1083, SPG4" ENSG00000021574 Spastin Q9UBP0 2 32063556-32157637 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Cell division, Differentiation, Neurogenesis" "Allosteric enzyme, Developmental protein, Isomerase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 55.2;Oligodendrocyte precursor cells: 59.3;Oligodendrocytes: 62.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017311 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA017311: AB_1857415" "unprognostic (1.89e-1)" "unprognostic (1.59e-2)" "unprognostic (5.33e-2)" "unprognostic (3.90e-2)" "unprognostic (3.75e-2)" "unprognostic (4.00e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.26e-2)" "unprognostic (2.35e-2)" "unprognostic (7.39e-2)" "unprognostic (5.98e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (4.15e-4)" "unprognostic (5.71e-2)" "unprognostic (3.04e-1)" "unprognostic (1.53e-2)" "unprognostic (1.13e-1)" 5.8 5.9 9.0 7.2 12.7 9.9 6.2 10.8 12.9 8.6 1.6 7.1 7.4 7.7 5.0 6.9 6.5 6.5 3.9 9.0 10.6 5.9 9.6 6.3 9.7 10.8 11.2 9.1 5.3 6.2 4.4 6.8 10.5 6.3 7.5 6.9 4.2 5.3 7.8 7.4 8.0 7.3 11.6 7.0 6.3 9.8 10.7 14.1 8.5 10.0 9.2 7.3 4.4 13.9 17.5 12.2 19.7 19.5 12.0 14.2 17.8 9.4 13.7 9.7 8.6 16.9 14.8 30.2 8.5 13.1 14.2 12.0 19.5 9.6 11.9 20.7 11.8 33.3 6.0 20.5 11.0 23.2 22.4 7.9 12.3 12.4 11.6 11.7 21.5 9.6 27.6 10.0 10.7 7.4 37.8 19.4 20.5 19.2 7.1 19.8 27.9 19.5 13.0 10.7 27.9 29.9 16.0 13.2 15.9 16.0 8.7 15.8 18.8 10.6 16.2 9.5 11.1 14.7 29.7 23.8 11.6 19.9 13.0 1.8 3.5 3.8 1.8 4.9 2.5 2.4 2.8 2.9 3.9 1.9 2.9 3.0 5.3 3.9 3.8 1.7 4.2 2.5 9.0 12.7 10.8 12.9 9.0 10.6 10.8 11.2 10.5 11.6 10.7 13.9 15.0 9.6 4.4 26.4 12.2 9.6 5.9 7.9 11.4 15.4 11.7 6.9 8.0 8.6 7.9 5.5 22.9 9.6 21.4 11.4 0.0 6.6 4.4 16.9 11.8 11.3 10.8 10.3 38.9 8.0 7.4 8.1 9.7 13.7 10.1 16.7 7.9 12.0 9.7 10.1 55.2 10.8 10.2 17.5 9.9 8.5 8.7 17.6 1.8 36.5 21.1 7.9 18.6 59.3 62.7 10.4 9.8 10.1 12.5 8.7 10.9 7.0 13.0 14.1 0.0 11.9 11.9 16.7 21.2 11.7 13.1 8.1 13.3 10.9 10.4 7.2 SPO11 "CT35, SPATA43, TOPVIA" ENSG00000054796 "SPO11 initiator of meiotic double stranded breaks" Q9Y5K1 20 57329803-57343994 "Enzymes, Plasma proteins, Predicted intracellular proteins" Meiosis "DNA-binding, Hydrolase, Isomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 8.5" "Cell type enriched" "Detected in some" 9 "Spermatocytes: 98.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.2 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SRR "ILV1, ISO1" ENSG00000167720 "Serine racemase" Q9GZT4 17 2303383-2325260 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Isomerase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007529, CAB015343" Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "CAB015343: AB_2195009, HPA007529: AB_2667853" "unprognostic (2.96e-1)" "unprognostic (7.86e-2)" "unprognostic (6.01e-2)" "prognostic favorable (6.20e-5)" "unprognostic (3.05e-1)" "unprognostic (1.57e-2)" "unprognostic (4.32e-2)" "unprognostic (9.97e-2)" "unprognostic (9.09e-2)" "unprognostic (4.85e-2)" "prognostic favorable (8.16e-4)" "unprognostic (5.17e-2)" "prognostic favorable (2.45e-6)" "unprognostic (6.14e-2)" "unprognostic (1.99e-1)" "unprognostic (1.89e-1)" "unprognostic (5.84e-2)" 10.5 7.8 11.0 6.6 11.5 13.9 8.9 12.5 13.1 6.8 13.0 9.4 6.9 7.5 10.3 10.9 8.7 8.3 10.9 9.4 13.4 9.0 8.2 6.1 6.6 11.2 12.4 8.4 11.9 12.3 4.9 5.4 12.7 8.4 7.5 16.6 10.7 7.7 15.6 11.8 5.9 7.0 11.1 6.9 8.0 7.1 12.5 9.0 11.8 6.7 5.4 8.4 5.3 11.8 14.8 27.0 42.7 17.9 24.9 24.4 22.8 29.8 20.2 19.4 20.5 25.3 18.1 27.5 4.1 29.1 14.3 30.2 12.2 11.4 24.6 32.6 26.0 14.6 20.3 9.6 22.5 4.3 8.0 22.9 11.5 41.4 21.0 21.2 28.6 28.2 15.2 19.8 43.9 8.4 28.7 5.8 10.0 13.8 19.9 45.5 48.8 13.3 22.9 6.9 9.2 23.4 26.8 3.3 14.3 14.6 20.7 10.3 21.3 21.4 14.7 24.7 19.0 16.7 26.0 5.1 36.9 13.7 29.8 4.3 8.1 5.6 8.8 8.4 9.1 10.1 11.2 9.1 15.6 10.2 9.2 12.1 1.0 15.7 14.0 11.0 8.8 8.5 11.0 11.5 12.5 13.1 9.4 13.4 11.2 12.4 12.7 11.1 12.5 11.8 5.0 3.2 3.7 3.6 2.1 2.9 3.5 17.4 1.8 8.5 5.5 4.6 4.2 1.5 8.4 1.8 0.0 5.9 3.4 3.0 13.7 9.6 1.9 6.6 5.5 5.4 1.8 5.2 3.5 6.6 3.2 5.7 3.6 4.6 0.0 13.2 8.2 3.2 9.3 16.8 4.9 2.5 12.2 4.6 4.9 1.5 4.1 3.7 5.4 4.7 9.3 11.0 5.2 5.0 7.8 6.7 0.8 5.3 6.1 2.9 2.9 6.3 10.2 5.6 0.0 4.6 6.5 23.3 13.1 4.7 2.4 3.4 2.3 9.7 3.5 4.0 TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.8" "Group enriched" "Detected in many" 4 "granulocytes: 71.0;Hofbauer cells: 88.8;Kupffer cells: 193.6;Macrophages: 132.9;Microglial cells: 191.1;monocytes: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 14 "basophil: 324.3;classical monocyte: 322.4;eosinophil: 333.6;intermediate monocyte: 466.0;myeloid DC: 129.0;neutrophil: 271.1;non-classical monocyte: 423.1" "Group enriched" "Detected in all" 22 "dendritic cells: 129.0;granulocytes: 333.6;monocytes: 466.0" "Cell line enhanced" "Detected in many" "NB-4: 76.7;PC-3: 23.7;RPTEC TERT1: 21.0;U-937: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA031257, HPA031258, HPA031259" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 890000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" "HPA031257: AB_2673812, HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" 13.2 10.8 5.3 28.1 5.1 24.8 8.2 5.4 5.9 5.4 5.8 10.1 10.3 3.2 2.0 5.4 4.9 21.2 3.3 4.5 6.8 5.8 12.8 23.9 12.4 10.0 6.6 2.9 3.6 2.9 2.3 14.2 8.8 6.4 13.0 1.6 9.0 4.0 1.0 1.3 11.9 12.6 8.9 57.8 11.2 1.4 9.7 15.1 1.8 3.3 8.3 13.9 2.1 14.7 0.2 5.4 0.3 0.1 1.2 3.9 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 12.1 0.0 0.3 0.0 0.0 0.0 0.0 9.4 0.7 17.8 0.0 0.0 1.6 6.2 15.3 2.1 0.0 0.0 0.9 1.1 2.3 0.1 0.6 2.2 0.6 0.2 2.4 76.7 0.2 18.0 23.7 2.6 0.0 1.2 21.0 0.0 0.2 1.1 0.2 0.0 0.8 0.0 0.0 14.4 2.0 0.6 0.2 1.4 1.0 4.6 0.9 0.3 0.4 60.8 1.7 324.3 322.4 333.6 7.3 466.0 11.9 8.3 13.5 3.7 129.0 4.5 2.3 1.3 271.1 11.9 423.1 22.6 13.9 216.7 5.3 5.1 5.4 5.9 4.5 6.8 10.0 6.6 8.8 8.9 9.7 14.7 3.9 3.2 10.8 8.1 9.9 0.4 1.2 0.5 2.8 1.0 3.0 3.0 1.1 5.7 1.7 1.8 6.2 0.6 16.4 0.8 9.8 5.2 0.4 1.0 0.6 5.0 1.8 12.8 1.2 9.5 0.5 2.9 7.1 3.8 71.0 0.5 16.8 8.6 88.8 3.3 1.8 1.9 12.2 193.6 19.5 0.7 0.3 132.9 3.6 191.1 63.7 4.9 26.8 3.0 5.9 4.4 7.9 0.0 16.4 5.8 0.2 6.3 1.0 4.1 19.7 1.3 1.7 0.5 0.7 26.2 0.6 0.5 13.4 0.3 2.7 1.2 TMX3 "FLJ20793, KIAA1830, PDIA13, TXNDC10" ENSG00000166479 "Thioredoxin related transmembrane protein 3" Q96JJ7 18 68673688-68715108 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014157 Uncertain "Intracellular and membrane" NA NA 36000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA014157: AB_1858469" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.14e-2)" "unprognostic (9.47e-2)" "unprognostic (6.82e-2)" "unprognostic (7.20e-2)" "unprognostic (4.96e-3)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (5.20e-2)" "unprognostic (9.83e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.69e-2)" "unprognostic (1.53e-2)" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" 22.7 16.2 11.7 24.1 13.0 14.1 19.2 14.2 15.4 15.0 9.9 12.7 18.2 16.6 20.4 14.1 13.8 16.5 20.8 13.5 13.2 14.6 16.2 19.5 27.9 11.1 11.2 13.0 11.9 15.9 9.6 19.8 12.1 17.7 16.3 26.0 10.6 13.0 11.0 16.7 18.8 21.0 11.4 22.6 14.0 11.4 12.1 23.3 17.7 21.0 22.7 20.1 11.2 11.5 11.1 17.4 32.9 25.9 66.6 70.7 24.5 85.7 91.0 61.0 67.7 8.4 31.9 31.4 16.6 125.4 25.9 40.8 21.9 42.9 92.8 30.3 19.6 28.8 27.4 14.7 70.6 62.0 45.7 56.5 27.1 66.2 59.2 61.8 78.4 27.0 18.9 42.5 73.1 6.9 33.3 19.6 13.9 9.1 28.2 30.7 65.5 38.5 51.7 24.2 31.5 24.5 42.0 26.7 31.8 32.4 17.6 52.1 76.4 108.4 30.0 24.7 63.6 28.4 30.4 29.4 65.5 50.1 81.3 2.2 2.9 2.4 3.8 4.7 5.5 3.1 3.9 3.6 4.7 2.1 4.3 4.4 0.7 4.9 3.3 6.4 4.4 2.7 11.7 13.0 14.2 15.4 13.5 13.2 11.1 11.2 12.1 11.4 12.1 11.5 31.4 28.9 27.8 36.2 25.0 20.3 17.2 17.6 12.0 29.1 21.0 15.6 25.1 10.0 18.8 16.5 18.8 15.0 44.3 10.6 1.9 15.2 8.9 18.7 38.5 27.3 18.0 17.0 77.9 10.2 20.8 34.5 13.3 25.6 20.3 24.2 34.2 26.6 18.6 26.9 45.6 13.8 14.2 23.3 26.8 3.3 24.2 23.9 24.9 32.8 18.2 20.5 20.6 49.8 53.1 15.4 15.4 16.6 29.8 19.4 17.5 8.0 28.8 32.5 39.5 23.6 32.0 23.8 28.3 21.7 24.3 12.4 23.3 22.9 9.4 16.6 TOP1 ENSG00000198900 "DNA topoisomerase I" P11387 20 41028822-41124487 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 801.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009058, HPA019039" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No Yes 7600 "Cluster 31: Non-specific - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nucleoli fibrillar center" "CAB009058: AB_2303554, HPA019039: AB_1858187" "unprognostic (1.46e-1)" "unprognostic (8.65e-2)" "unprognostic (1.33e-2)" "unprognostic (1.92e-3)" "unprognostic (5.05e-2)" "unprognostic (1.49e-3)" "prognostic unfavorable (6.42e-4)" "unprognostic (5.86e-2)" "unprognostic (1.51e-1)" "unprognostic (4.60e-2)" "unprognostic (3.74e-3)" "unprognostic (6.51e-2)" "unprognostic (8.65e-2)" "unprognostic (4.70e-2)" "unprognostic (5.14e-1)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" 37.9 36.7 17.4 49.9 18.6 74.9 27.9 21.8 25.1 26.9 25.3 36.9 42.6 27.9 34.4 36.7 22.4 37.2 19.1 18.0 18.9 39.0 47.5 40.0 59.9 18.5 18.4 24.3 28.6 26.7 22.4 50.2 18.1 31.8 37.3 25.5 26.7 24.2 21.3 26.5 42.6 23.9 18.7 38.5 36.5 18.9 18.8 58.9 37.6 20.2 60.6 42.7 28.8 19.2 105.2 71.7 131.4 108.2 52.2 61.8 129.8 92.6 81.0 105.0 94.8 190.5 127.6 296.4 96.4 48.5 112.3 98.9 159.1 147.2 153.0 64.9 81.6 378.6 54.9 139.0 135.4 165.1 124.0 69.8 76.4 102.4 166.8 94.0 111.5 98.1 167.8 98.7 120.9 233.2 235.3 119.7 106.3 104.1 131.6 197.7 123.1 157.7 121.4 95.2 108.6 75.4 145.4 88.3 95.0 94.2 98.6 146.4 109.9 84.7 71.3 78.8 100.9 62.7 75.6 338.3 113.7 91.1 82.0 12.6 9.9 16.8 6.6 10.3 8.3 10.5 7.3 7.0 9.5 10.1 7.7 6.9 19.1 6.3 13.2 18.8 9.0 5.4 17.4 18.6 21.8 25.1 18.0 18.9 18.5 18.4 18.1 18.7 18.8 19.2 116.9 118.6 201.5 66.0 117.6 245.9 338.0 90.3 153.7 98.2 90.5 75.7 49.7 78.6 170.3 99.3 60.5 192.1 137.1 194.1 74.3 94.4 10.0 151.3 167.4 115.1 91.8 486.5 86.9 65.8 175.4 121.4 84.1 259.2 78.6 119.1 67.1 131.7 99.2 72.3 77.4 126.9 69.2 101.2 109.1 12.8 59.7 151.6 72.9 74.9 95.4 88.0 78.2 87.4 90.7 119.2 169.8 69.6 234.1 162.3 94.1 136.2 68.3 87.0 85.5 135.5 130.8 116.8 54.6 129.4 214.2 801.5 111.5 123.7 117.8 237.7 TOP1MT ENSG00000184428 "DNA topoisomerase I mitochondrial" Q969P6 8 143304384-143359979 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "MOLT-4: 197.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001915, HPA021542" Approved Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 32: Non-specific - Translation" Mitochondria "HPA001915: AB_1080331, HPA021542: AB_1858186" "unprognostic (5.02e-3)" "unprognostic (3.79e-2)" "unprognostic (6.57e-2)" "unprognostic (6.92e-3)" "unprognostic (2.32e-2)" "unprognostic (1.04e-2)" "unprognostic (3.05e-3)" "unprognostic (1.44e-1)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.42e-2)" "prognostic unfavorable (1.52e-7)" "unprognostic (3.66e-2)" "unprognostic (3.62e-2)" "unprognostic (8.55e-3)" "unprognostic (5.66e-3)" 14.0 17.4 7.3 9.4 6.1 48.2 13.7 2.5 7.8 23.2 4.0 12.6 7.6 11.7 4.8 18.4 13.4 9.2 7.6 8.5 5.8 14.4 30.3 10.5 12.0 7.0 4.7 32.1 18.9 10.1 9.2 7.4 7.1 13.2 9.7 2.0 14.2 8.1 7.3 22.6 11.6 7.8 2.9 12.6 12.9 23.4 5.4 21.4 21.9 3.4 11.4 17.8 19.1 6.4 25.5 38.3 15.8 59.4 22.0 24.5 28.1 11.6 14.8 20.5 21.1 48.4 35.8 74.2 42.6 16.2 14.7 26.8 33.8 21.3 17.6 29.5 52.4 65.6 21.5 49.5 24.8 44.4 68.4 25.1 22.3 17.4 24.8 17.7 25.0 21.1 80.5 28.2 18.3 106.3 197.8 87.9 27.6 54.9 65.4 24.7 20.7 112.2 15.3 40.4 28.1 34.1 33.2 29.3 61.7 19.3 19.3 72.5 16.5 14.3 57.7 16.4 30.2 15.2 17.0 38.0 24.1 64.9 17.4 31.4 10.5 0.5 6.2 6.3 6.3 28.9 11.3 8.6 35.3 14.4 24.2 18.8 0.7 0.4 1.2 30.9 3.2 9.2 7.3 6.1 2.5 7.8 8.5 5.8 7.0 4.7 7.1 2.9 5.4 6.4 11.4 6.4 8.6 3.3 11.9 23.7 32.3 13.1 14.2 1.2 15.3 11.6 3.3 10.0 10.5 9.2 0.0 11.7 7.3 6.7 7.9 11.4 29.3 3.9 10.9 7.7 4.9 41.3 2.5 9.3 23.6 8.9 5.6 5.8 7.0 24.7 6.4 12.1 11.1 3.3 3.5 11.3 2.0 8.8 24.9 11.1 8.7 9.4 21.4 0.0 9.3 1.4 2.1 1.5 2.9 7.1 11.2 4.5 6.1 29.7 2.8 15.8 3.1 0.2 6.6 13.5 10.0 31.3 36.4 17.8 23.9 10.1 8.6 21.4 20.8 22.8 TOP2A TOP2 ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388525-40417896 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 127.8;testis: 65.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 216.8;Granulosa cells: 117.5;Spermatocytes: 621.2;Spermatogonia: 269.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 2.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 4.2;white matter: 8.0" "Low region specificity" "Detected in some" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002448: AB_564035, HPA006458: AB_1858189, HPA026773: AB_1858190" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-3)" "unprognostic (9.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.92e-6)" "prognostic unfavorable (4.99e-4)" "unprognostic (6.21e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.83e-5)" "unprognostic (5.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" 2.2 2.5 0.2 20.0 0.2 42.0 5.4 0.1 0.7 5.0 1.1 17.8 18.1 3.9 0.3 29.0 1.5 2.6 1.2 0.2 0.2 1.2 2.8 4.1 40.3 0.2 0.8 1.0 0.9 0.3 0.3 15.9 0.5 1.4 19.8 0.1 4.3 0.5 0.3 15.3 17.0 7.6 0.2 9.9 8.9 65.7 1.1 127.8 1.9 0.2 42.5 6.0 9.6 0.4 212.6 275.6 343.1 158.0 16.8 33.9 76.3 283.3 151.5 255.0 224.2 130.5 157.6 339.4 140.1 96.7 152.7 326.5 266.8 113.5 339.5 182.7 177.8 224.8 167.9 216.7 1.6 318.4 228.6 7.4 9.2 179.8 181.4 55.1 136.3 216.5 247.5 225.8 279.2 72.6 372.3 209.6 143.0 152.4 108.3 310.7 531.9 141.3 61.6 133.3 201.6 144.6 229.3 281.4 89.4 198.2 236.9 143.2 90.3 167.0 233.2 195.5 276.7 128.4 154.9 290.7 94.3 214.9 285.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.3 0.3 0.1 0.1 0.0 0.0 0.1 1.4 0.1 0.0 2.4 0.4 0.2 0.2 0.1 0.7 0.2 0.2 0.2 0.8 0.5 0.2 1.1 0.4 1.0 0.0 2.0 0.3 17.4 11.7 3.7 15.0 2.2 0.0 18.7 17.1 1.3 2.8 5.8 0.0 0.0 72.9 6.1 19.8 0.0 0.8 20.3 12.7 15.8 9.3 0.0 216.8 0.2 0.0 92.4 23.3 23.0 10.0 0.0 117.5 20.7 5.4 83.5 0.0 0.1 34.2 18.3 33.9 13.2 19.1 4.7 14.1 1.8 0.0 2.6 0.0 3.1 0.0 0.1 0.3 3.5 1.9 31.3 3.1 3.4 0.1 1.8 0.0 72.3 0.5 19.5 621.2 269.6 45.1 6.1 8.9 14.8 4.3 61.0 6.9 TOP2B ENSG00000077097 "DNA topoisomerase II beta" Q02880 3 25597905-25664907 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Autism spectrum disorder, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 569.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004601, HPA024120, HPA050441" Supported Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB004601: AB_628384, HPA024120: AB_1858191, HPA050441: AB_2681127" "unprognostic (2.90e-2)" "unprognostic (5.17e-2)" "unprognostic (7.21e-3)" "unprognostic (2.42e-1)" "unprognostic (1.60e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (7.86e-2)" "unprognostic (1.89e-1)" "unprognostic (2.84e-1)" "unprognostic (7.14e-2)" "unprognostic (1.08e-1)" "prognostic favorable (2.43e-4)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" "unprognostic (1.49e-1)" "unprognostic (7.93e-2)" 27.1 25.5 15.3 38.9 17.6 49.1 34.7 25.2 16.5 36.2 12.0 30.1 28.8 42.9 25.5 34.1 29.7 26.2 38.5 15.3 16.0 32.1 27.7 28.0 50.4 13.5 16.2 40.6 28.8 53.2 11.7 34.4 15.1 38.7 33.3 112.3 27.1 34.2 29.9 32.4 28.6 34.2 16.4 36.4 32.1 19.5 14.6 82.5 45.8 36.7 46.6 43.7 18.5 25.3 57.6 58.6 125.9 155.3 41.1 51.7 50.1 54.4 69.6 49.4 53.9 30.1 44.6 176.9 37.1 79.2 30.5 47.7 105.6 60.5 82.5 85.5 56.7 268.5 71.2 50.6 28.9 212.8 137.4 37.1 29.7 55.3 48.2 49.8 81.7 118.6 92.0 84.3 64.4 64.0 138.5 52.5 95.9 38.5 44.1 569.9 71.0 82.6 43.9 199.5 63.2 109.7 81.1 57.4 49.9 72.2 59.7 187.1 78.7 68.3 52.6 55.2 58.9 129.6 78.6 185.1 44.9 155.6 46.5 3.2 1.4 2.8 3.0 1.7 3.3 2.0 2.9 3.1 2.2 2.5 3.3 3.0 1.0 3.9 2.6 2.8 2.3 1.1 15.3 17.6 25.2 16.5 15.3 16.0 13.5 16.2 15.1 16.4 14.6 25.3 36.4 64.1 62.7 65.3 47.3 39.1 47.9 30.9 31.3 62.4 44.4 31.9 121.5 34.3 36.1 25.8 56.3 47.8 65.8 29.9 13.7 34.3 3.6 48.0 58.8 36.6 59.3 65.6 77.8 33.4 24.5 40.2 28.5 45.1 34.1 71.4 25.0 35.1 26.2 60.6 89.8 32.3 20.3 40.7 50.1 6.0 39.1 45.3 23.2 43.1 49.8 51.3 68.0 76.4 113.0 35.5 22.2 33.4 46.0 56.2 20.6 25.6 39.2 95.7 32.9 56.5 51.0 94.9 44.0 57.9 37.6 46.7 53.7 48.4 39.2 64.3 TOP3A "TOP3, ZGRF7" ENSG00000177302 "DNA topoisomerase III alpha" Q13472 17 18271428-18315007 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, Disease variant, Dwarfism, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002449 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "CAB002449: AB_564037" "unprognostic (5.49e-2)" "unprognostic (9.04e-2)" "unprognostic (8.99e-2)" "unprognostic (7.24e-3)" "unprognostic (4.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.33e-3)" "unprognostic (6.54e-2)" "unprognostic (2.34e-1)" "unprognostic (2.74e-1)" "prognostic favorable (1.39e-4)" "prognostic unfavorable (4.59e-4)" "unprognostic (5.58e-2)" "unprognostic (8.80e-2)" "unprognostic (3.53e-2)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" 9.4 8.0 1.9 3.3 1.8 5.7 8.6 3.1 2.6 8.6 2.1 7.8 2.3 8.4 1.6 8.6 8.5 2.1 6.0 1.8 1.8 7.0 11.2 7.7 3.6 1.7 1.6 7.5 7.7 2.6 8.9 2.5 1.7 7.7 2.4 2.1 8.1 1.7 10.0 11.3 8.2 2.6 1.4 11.4 7.6 11.7 2.0 4.2 6.7 2.5 3.3 8.5 7.8 2.0 9.3 14.2 9.4 11.1 3.8 4.6 10.9 9.4 4.9 14.2 12.8 22.4 3.4 13.7 6.0 6.5 6.6 11.7 12.6 6.7 11.5 11.6 11.4 13.1 15.2 7.9 4.3 5.8 11.9 2.9 4.6 15.0 8.7 2.9 7.3 11.5 11.3 5.7 6.1 6.4 15.2 5.9 8.7 13.8 6.8 17.4 22.6 14.8 3.2 8.1 7.7 13.6 12.6 8.3 8.4 24.5 16.1 6.5 6.5 10.6 8.1 18.2 15.4 5.8 13.7 10.4 6.6 8.0 10.5 1.1 3.1 3.4 1.8 2.7 1.3 0.7 1.3 1.6 1.3 0.8 1.1 1.2 4.2 2.2 1.5 1.2 1.2 2.0 1.9 1.8 3.1 2.6 1.8 1.8 1.7 1.6 1.7 1.4 2.0 2.0 5.3 6.4 4.8 6.5 9.7 2.0 4.5 4.5 6.8 20.8 6.2 3.9 3.1 5.7 7.4 11.0 39.6 7.4 11.8 4.6 3.9 4.2 7.2 5.0 8.7 6.2 0.0 9.9 16.4 3.7 6.9 6.3 6.6 6.3 5.1 12.1 6.4 7.0 5.4 21.9 17.2 4.2 4.1 12.4 6.3 7.9 8.1 11.6 1.8 12.2 13.9 6.4 15.5 11.6 11.2 3.6 2.8 6.4 12.0 5.8 3.8 2.1 6.5 22.2 13.1 9.3 6.6 26.7 25.5 5.2 3.4 4.4 9.0 13.1 5.9 5.0 TOP3B ENSG00000100038 "DNA topoisomerase III beta" O95985 22 21957025-21982813 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 112.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072114 Approved Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA072114: " "unprognostic (1.03e-1)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (3.37e-1)" "unprognostic (5.04e-2)" "unprognostic (2.27e-1)" "unprognostic (3.93e-1)" "unprognostic (2.15e-2)" "unprognostic (2.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-2)" "unprognostic (1.96e-2)" "unprognostic (1.69e-2)" "unprognostic (1.21e-1)" "unprognostic (3.53e-2)" "unprognostic (1.11e-4)" 10.6 12.0 5.5 10.1 6.9 16.2 11.2 7.5 8.3 17.9 12.2 13.7 11.1 13.5 7.1 14.8 13.5 7.4 11.8 6.0 5.7 13.9 17.0 13.7 12.7 5.9 5.0 20.3 12.7 7.4 12.9 8.4 6.1 16.7 9.9 6.9 13.9 6.8 10.4 14.7 17.7 9.7 4.0 25.0 13.5 11.1 6.3 13.6 14.3 5.7 13.4 11.4 15.5 8.1 22.1 21.1 40.9 16.8 14.8 12.3 25.7 14.2 17.6 32.1 28.3 22.2 9.3 29.9 10.5 14.9 13.4 39.6 18.6 25.2 25.9 15.3 45.4 23.5 31.4 24.1 20.1 32.3 14.9 6.1 37.5 26.8 12.7 18.6 27.1 17.2 112.5 15.7 15.2 22.3 20.6 25.0 17.0 15.8 19.9 31.6 27.1 4.6 15.8 28.9 26.7 19.3 17.4 15.4 13.7 16.4 11.9 20.7 19.9 13.2 27.6 13.0 17.6 23.2 20.8 28.2 10.2 19.4 14.0 1.9 4.3 1.8 5.5 4.4 3.8 4.5 3.6 3.9 4.7 4.9 3.3 3.5 1.5 4.3 2.6 5.4 4.2 3.7 5.5 6.9 7.5 8.3 6.0 5.7 5.9 5.0 6.1 4.0 6.3 8.1 7.2 0.0 2.6 12.1 7.2 1.8 2.6 6.2 2.8 4.6 3.7 3.9 0.2 8.6 5.0 3.7 10.4 5.2 7.2 7.0 1.9 4.8 1.3 5.3 6.7 5.7 4.8 2.1 8.9 4.3 3.6 4.3 12.2 5.0 1.3 15.0 7.9 7.1 4.0 1.7 7.7 5.3 4.1 3.4 3.8 1.8 10.5 5.1 5.4 6.5 4.3 3.1 5.2 4.5 9.2 6.4 4.6 7.5 6.1 3.4 4.5 2.8 8.2 6.1 6.6 4.9 9.6 6.6 4.9 3.6 1.6 4.0 5.9 7.6 5.8 2.9 TPI1 ENSG00000111669 "Triosephosphate isomerase 1" P60174 12 6867119-6870948 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Glycolysis" "Isomerase, Lyase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2470.8;tongue: 2005.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050924, HPA053568" Uncertain Approved Nucleoplasm,Vesicles NA NA 170000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Vesicles "HPA050924: AB_2681276, HPA053568: AB_2682193" "unprognostic (2.85e-1)" "unprognostic (5.58e-3)" "unprognostic (1.65e-1)" "unprognostic (1.62e-2)" "unprognostic (6.94e-2)" "unprognostic (2.31e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (4.14e-3)" "unprognostic (7.49e-2)" "unprognostic (2.13e-2)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (6.54e-4)" "unprognostic (7.04e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" 340.4 588.6 446.2 269.7 480.2 334.8 274.5 476.5 541.9 314.1 446.9 425.6 421.0 240.5 220.2 764.4 248.2 216.8 819.8 481.0 462.0 609.0 536.1 308.6 253.9 459.2 460.4 269.9 238.1 496.4 236.8 287.2 467.2 272.1 435.3 625.0 377.6 273.3 2470.8 410.1 404.5 301.5 429.7 291.4 329.0 239.8 503.5 200.3 269.1 2005.8 410.4 363.8 440.6 454.4 1556.8 1350.5 706.1 1094.6 666.5 696.6 1236.3 1097.5 1184.9 1999.1 2407.5 1409.9 823.0 903.4 212.7 1069.7 1042.4 748.8 1671.0 1812.3 2189.4 1196.4 1265.1 1172.0 924.4 926.2 496.8 1351.5 924.0 764.0 739.7 1537.8 1305.0 2816.1 1233.3 451.0 615.0 336.5 1554.5 1130.0 709.6 1119.5 1741.0 1302.3 855.9 413.5 1156.1 930.7 1261.4 1061.1 497.2 830.0 953.3 977.8 542.7 1452.6 224.4 1003.2 778.2 1068.0 914.6 703.1 1631.7 653.4 285.7 1327.8 2153.1 821.2 784.9 1708.8 2304.1 2375.2 824.6 2402.3 845.7 863.3 820.0 808.0 2656.1 800.9 570.5 703.0 934.3 1387.7 2165.7 482.0 1106.3 4679.5 446.2 480.2 476.5 541.9 481.0 462.0 459.2 460.4 467.2 429.7 503.5 454.4 311.5 134.6 204.2 34.6 290.6 684.8 553.8 1756.4 414.9 284.6 294.3 303.3 552.5 391.7 673.0 389.9 110.5 1017.0 278.2 850.3 1508.5 1361.5 203.0 280.8 307.0 352.0 425.5 243.3 38.4 786.5 1824.0 386.5 408.3 343.9 362.8 364.8 276.6 547.3 937.3 297.8 33.7 567.2 1151.5 386.7 750.4 683.5 279.0 482.8 674.1 18.7 1129.8 739.6 312.0 17.1 26.7 1081.5 889.4 263.3 427.9 556.2 1595.9 1642.7 401.2 298.0 197.2 270.5 551.3 14.9 79.0 690.4 615.9 1530.4 352.9 869.2 827.0 652.5