Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [nTPM]"	"Tissue RNA - adrenal gland [nTPM]"	"Tissue RNA - amygdala [nTPM]"	"Tissue RNA - appendix [nTPM]"	"Tissue RNA - basal ganglia [nTPM]"	"Tissue RNA - bone marrow [nTPM]"	"Tissue RNA - breast [nTPM]"	"Tissue RNA - cerebellum [nTPM]"	"Tissue RNA - cerebral cortex [nTPM]"	"Tissue RNA - cervix [nTPM]"	"Tissue RNA - choroid plexus [nTPM]"	"Tissue RNA - colon [nTPM]"	"Tissue RNA - duodenum [nTPM]"	"Tissue RNA - endometrium 1 [nTPM]"	"Tissue RNA - epididymis [nTPM]"	"Tissue RNA - esophagus [nTPM]"	"Tissue RNA - fallopian tube [nTPM]"	"Tissue RNA - gallbladder [nTPM]"	"Tissue RNA - heart muscle [nTPM]"	"Tissue RNA - hippocampal formation [nTPM]"	"Tissue RNA - hypothalamus [nTPM]"	"Tissue RNA - kidney [nTPM]"	"Tissue RNA - liver [nTPM]"	"Tissue RNA - lung [nTPM]"	"Tissue RNA - lymph node [nTPM]"	"Tissue RNA - medulla oblongata [nTPM]"	"Tissue RNA - midbrain [nTPM]"	"Tissue RNA - ovary [nTPM]"	"Tissue RNA - pancreas [nTPM]"	"Tissue RNA - parathyroid gland [nTPM]"	"Tissue RNA - pituitary gland [nTPM]"	"Tissue RNA - placenta [nTPM]"	"Tissue RNA - pons [nTPM]"	"Tissue RNA - prostate [nTPM]"	"Tissue RNA - rectum [nTPM]"	"Tissue RNA - retina [nTPM]"	"Tissue RNA - salivary gland [nTPM]"	"Tissue RNA - seminal vesicle [nTPM]"	"Tissue RNA - skeletal muscle [nTPM]"	"Tissue RNA - skin 1 [nTPM]"	"Tissue RNA - small intestine [nTPM]"	"Tissue RNA - smooth muscle [nTPM]"	"Tissue RNA - spinal cord [nTPM]"	"Tissue RNA - spleen [nTPM]"	"Tissue RNA - stomach 1 [nTPM]"	"Tissue RNA - testis [nTPM]"	"Tissue RNA - thalamus [nTPM]"	"Tissue RNA - thymus [nTPM]"	"Tissue RNA - thyroid gland [nTPM]"	"Tissue RNA - tongue [nTPM]"	"Tissue RNA - tonsil [nTPM]"	"Tissue RNA - urinary bladder [nTPM]"	"Tissue RNA - vagina [nTPM]"	"Tissue RNA - white matter [nTPM]"	"Cell RNA - A-431 [nTPM]"	"Cell RNA - A549 [nTPM]"	"Cell RNA - AF22 [nTPM]"	"Cell RNA - AN3-CA [nTPM]"	"Cell RNA - ASC diff [nTPM]"	"Cell RNA - ASC TERT1 [nTPM]"	"Cell RNA - BEWO [nTPM]"	"Cell RNA - BJ [nTPM]"	"Cell RNA - BJ hTERT+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]"	"Cell RNA - CACO-2 [nTPM]"	"Cell RNA - CAPAN-2 [nTPM]"	"Cell RNA - Daudi [nTPM]"	"Cell RNA - EFO-21 [nTPM]"	"Cell RNA - fHDF/TERT166 [nTPM]"	"Cell RNA - GAMG [nTPM]"	"Cell RNA - HaCaT [nTPM]"	"Cell RNA - HAP1 [nTPM]"	"Cell RNA - HBEC3-KT [nTPM]"	"Cell RNA - HBF TERT88 [nTPM]"	"Cell RNA - HDLM-2 [nTPM]"	"Cell RNA - HEK 293 [nTPM]"	"Cell RNA - HEL [nTPM]"	"Cell RNA - HeLa [nTPM]"	"Cell RNA - Hep G2 [nTPM]"	"Cell RNA - HHSteC [nTPM]"	"Cell RNA - HL-60 [nTPM]"	"Cell RNA - HMC-1 [nTPM]"	"Cell RNA - HSkMC [nTPM]"	"Cell RNA - hTCEpi [nTPM]"	"Cell RNA - hTEC/SVTERT24-B [nTPM]"	"Cell RNA - hTERT-HME1 [nTPM]"	"Cell RNA - hTERT-RPE1 [nTPM]"	"Cell RNA - HUVEC TERT2 [nTPM]"	"Cell RNA - JURKAT [nTPM]"	"Cell RNA - K-562 [nTPM]"	"Cell RNA - Karpas-707 [nTPM]"	"Cell RNA - LHCN-M2 [nTPM]"	"Cell RNA - MCF7 [nTPM]"	"Cell RNA - MOLT-4 [nTPM]"	"Cell RNA - NB-4 [nTPM]"	"Cell RNA - NTERA-2 [nTPM]"	"Cell RNA - OE19 [nTPM]"	"Cell RNA - PC-3 [nTPM]"	"Cell RNA - REH [nTPM]"	"Cell RNA - RH-30 [nTPM]"	"Cell RNA - RPMI-8226 [nTPM]"	"Cell RNA - RPTEC TERT1 [nTPM]"	"Cell RNA - RT4 [nTPM]"	"Cell RNA - SCLC-21H [nTPM]"	"Cell RNA - SH-SY5Y [nTPM]"	"Cell RNA - SiHa [nTPM]"	"Cell RNA - SK-BR-3 [nTPM]"	"Cell RNA - SK-MEL-30 [nTPM]"	"Cell RNA - SuSa [nTPM]"	"Cell RNA - T-47d [nTPM]"	"Cell RNA - THP-1 [nTPM]"	"Cell RNA - TIME [nTPM]"	"Cell RNA - U-138 MG [nTPM]"	"Cell RNA - U-2 OS [nTPM]"	"Cell RNA - U-2197 [nTPM]"	"Cell RNA - U-251 MG [nTPM]"	"Cell RNA - U-266/70 [nTPM]"	"Cell RNA - U-266/84 [nTPM]"	"Cell RNA - U-698 [nTPM]"	"Cell RNA - U-87 MG [nTPM]"	"Cell RNA - U-937 [nTPM]"	"Cell RNA - WM-115 [nTPM]"	"Blood RNA - basophil [nTPM]"	"Blood RNA - classical monocyte [nTPM]"	"Blood RNA - eosinophil [nTPM]"	"Blood RNA - gdT-cell [nTPM]"	"Blood RNA - intermediate monocyte [nTPM]"	"Blood RNA - MAIT T-cell [nTPM]"	"Blood RNA - memory B-cell [nTPM]"	"Blood RNA - memory CD4 T-cell [nTPM]"	"Blood RNA - memory CD8 T-cell [nTPM]"	"Blood RNA - myeloid DC [nTPM]"	"Blood RNA - naive B-cell [nTPM]"	"Blood RNA - naive CD4 T-cell [nTPM]"	"Blood RNA - naive CD8 T-cell [nTPM]"	"Blood RNA - neutrophil [nTPM]"	"Blood RNA - NK-cell [nTPM]"	"Blood RNA - non-classical monocyte [nTPM]"	"Blood RNA - plasmacytoid DC [nTPM]"	"Blood RNA - T-reg [nTPM]"	"Blood RNA - total PBMC [nTPM]"	"Brain RNA - amygdala [nTPM]"	"Brain RNA - basal ganglia [nTPM]"	"Brain RNA - cerebellum [nTPM]"	"Brain RNA - cerebral cortex [nTPM]"	"Brain RNA - hippocampal formation [nTPM]"	"Brain RNA - hypothalamus [nTPM]"	"Brain RNA - medulla oblongata [nTPM]"	"Brain RNA - midbrain [nTPM]"	"Brain RNA - pons [nTPM]"	"Brain RNA - spinal cord [nTPM]"	"Brain RNA - thalamus [nTPM]"	"Brain RNA - white matter [nTPM]"	"Single Cell Type RNA - Adipocytes [nTPM]"	"Single Cell Type RNA - Alveolar cells type 1 [nTPM]"	"Single Cell Type RNA - Alveolar cells type 2 [nTPM]"	"Single Cell Type RNA - Astrocytes [nTPM]"	"Single Cell Type RNA - B-cells [nTPM]"	"Single Cell Type RNA - Basal keratinocytes [nTPM]"	"Single Cell Type RNA - Basal prostatic cells [nTPM]"	"Single Cell Type RNA - Basal respiratory cells [nTPM]"	"Single Cell Type RNA - Basal squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Bipolar cells [nTPM]"	"Single Cell Type RNA - Breast glandular cells [nTPM]"	"Single Cell Type RNA - Breast myoepithelial cells [nTPM]"	"Single Cell Type RNA - Cardiomyocytes [nTPM]"	"Single Cell Type RNA - Cholangiocytes [nTPM]"	"Single Cell Type RNA - Club cells [nTPM]"	"Single Cell Type RNA - Collecting duct cells [nTPM]"	"Single Cell Type RNA - Cone photoreceptor cells [nTPM]"	"Single Cell Type RNA - Cytotrophoblasts [nTPM]"	"Single Cell Type RNA - dendritic cells [nTPM]"	"Single Cell Type RNA - Distal enterocytes [nTPM]"	"Single Cell Type RNA - Distal tubular cells [nTPM]"	"Single Cell Type RNA - Ductal cells [nTPM]"	"Single Cell Type RNA - Early spermatids [nTPM]"	"Single Cell Type RNA - Endometrial ciliated cells [nTPM]"	"Single Cell Type RNA - Endometrial stromal cells [nTPM]"	"Single Cell Type RNA - Endothelial cells [nTPM]"	"Single Cell Type RNA - Enteroendocrine cells [nTPM]"	"Single Cell Type RNA - Erythroid cells [nTPM]"	"Single Cell Type RNA - Excitatory neurons [nTPM]"	"Single Cell Type RNA - Exocrine glandular cells [nTPM]"	"Single Cell Type RNA - Extravillous trophoblasts [nTPM]"	"Single Cell Type RNA - Fibroblasts [nTPM]"	"Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]"	"Single Cell Type RNA - Glandular and luminal cells [nTPM]"	"Single Cell Type RNA - granulocytes [nTPM]"	"Single Cell Type RNA - Granulosa cells [nTPM]"	"Single Cell Type RNA - Hepatic stellate cells [nTPM]"	"Single Cell Type RNA - Hepatocytes [nTPM]"	"Single Cell Type RNA - Hofbauer cells [nTPM]"	"Single Cell Type RNA - Horizontal cells [nTPM]"	"Single Cell Type RNA - Inhibitory neurons [nTPM]"	"Single Cell Type RNA - Intestinal goblet cells [nTPM]"	"Single Cell Type RNA - Ionocytes [nTPM]"	"Single Cell Type RNA - Kupffer cells [nTPM]"	"Single Cell Type RNA - Langerhans cells [nTPM]"	"Single Cell Type RNA - Late spermatids [nTPM]"	"Single Cell Type RNA - Leydig cells [nTPM]"	"Single Cell Type RNA - Macrophages [nTPM]"	"Single Cell Type RNA - Melanocytes [nTPM]"	"Single Cell Type RNA - Microglial cells [nTPM]"	"Single Cell Type RNA - monocytes [nTPM]"	"Single Cell Type RNA - Muller glia cells [nTPM]"	"Single Cell Type RNA - NK-cells [nTPM]"	"Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]"	"Single Cell Type RNA - Oligodendrocytes [nTPM]"	"Single Cell Type RNA - Pancreatic endocrine cells [nTPM]"	"Single Cell Type RNA - Paneth cells [nTPM]"	"Single Cell Type RNA - Peritubular cells [nTPM]"	"Single Cell Type RNA - Plasma cells [nTPM]"	"Single Cell Type RNA - Prostatic glandular cells [nTPM]"	"Single Cell Type RNA - Proximal enterocytes [nTPM]"	"Single Cell Type RNA - Proximal tubular cells [nTPM]"	"Single Cell Type RNA - Respiratory ciliated cells [nTPM]"	"Single Cell Type RNA - Rod photoreceptor cells [nTPM]"	"Single Cell Type RNA - Sertoli cells [nTPM]"	"Single Cell Type RNA - Skeletal myocytes [nTPM]"	"Single Cell Type RNA - Smooth muscle cells [nTPM]"	"Single Cell Type RNA - Spermatocytes [nTPM]"	"Single Cell Type RNA - Spermatogonia [nTPM]"	"Single Cell Type RNA - Squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Suprabasal keratinocytes [nTPM]"	"Single Cell Type RNA - Syncytiotrophoblasts [nTPM]"	"Single Cell Type RNA - T-cells [nTPM]"	"Single Cell Type RNA - Theca cells [nTPM]"	"Single Cell Type RNA - Undifferentiated cells [nTPM]"	"Single Cell Type RNA - Urothelial cells [nTPM]"
ABCB11	"ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP"	ENSG00000073734	"ATP binding cassette subfamily B member 11"	O95342	2	168915498-169031324	"Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	Transport	Translocase	"Disease variant, Intrahepatic cholestasis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	13	"liver: 80.8"	"Cell type enhanced"	"Detected in some"		"Alveolar cells type 1: 41.7;Alveolar cells type 2: 44.1;Club cells: 19.3;Early spermatids: 16.5;granulocytes: 24.0;Hepatocytes: 20.4"	"Cancer enriched"	"Detected in single"	87	"liver cancer: 6.7"	"Low region specificity"	"Detected in single"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"NB-4: 1.6;RT4: 1.6;TIME: 1.1"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA019035	Enhanced		Uncertain	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA				"Cluster 62: Liver - Hemostasis"	"Cluster 24: NB-4 - Immune response"	"Cluster 11: Alveolar cells - Smell perception"	"Nucleoplasm, Plasma membrane, Cytosol"		"HPA019035: AB_1844429"	"unprognostic (7.78e-2)"	"unprognostic (3.92e-1)"	"unprognostic (8.31e-2)"	"unprognostic (2.56e-1)"	"unprognostic (1.13e-1)"	"unprognostic (5.10e-2)"	"unprognostic (1.00e-2)"	"unprognostic (9.71e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.72e-2)"	"unprognostic (5.64e-3)"	"unprognostic (3.71e-1)"	"unprognostic (5.26e-6)"	"unprognostic (7.12e-2)"	"unprognostic (1.82e-1)"		"unprognostic (1.94e-1)"	1.5	0.0	0.3	0.1	0.3	0.0	0.6	0.3	0.5	0.0	0.2	1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.2	0.0	80.8	0.0	0.1	1.0	0.6	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.4	0.4	0.1	0.0	0.0	1.1	0.0	0.0	0.3	0.1	0.0	6.2	0.2	0.0	0.0	0.0	0.1	1.1	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	1.6	0.0	0.1	0.4	0.1	0.1	0.0	0.0	1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	1.1	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.3	0.3	0.5	0.2	0.2	1.0	0.6	0.5	0.3	0.2	0.3	0.0	41.7	44.1	1.3	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.4	0.0	19.3	0.0	0.0	0.0	0.0	0.7	0.0	0.1	16.5	0.1	0.0	1.8	0.0	2.7	0.8	0.0	0.0	6.6	0.0	0.0	24.0	0.0	0.0	20.4	0.0	0.0	0.3	0.0	0.0	0.3	0.0	9.1	0.0	3.8	0.0	0.0	0.0	0.5	0.0	0.0	0.3	0.6	0.0	0.0	0.0	0.1	0.0	0.0	8.9	0.1	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.1	2.6	0.2	0.0	0.6
ABCB4	"GBD1, MDR2, MDR3, PFIC-3, PGY3"	ENSG00000005471	"ATP binding cassette subfamily B member 4"	P21439	7	87401696-87480435	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Lipid transport, Transport"	Translocase	"Disease variant, Intrahepatic cholestasis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	16	"liver: 123.2"	"Cell type enriched"	"Detected in some"	6	"Hepatocytes: 256.1"	"Cancer enriched"	"Detected in some"	11	"liver cancer: 16.3"	"Low region specificity"	"Detected in single"			"Group enriched"	"Detected in some"	5	"memory B-cell: 4.4;naive B-cell: 8.1"	"Lineage enriched"	"Detected in many"	7	"B-cells: 8.1"	"Group enriched"	"Detected in some"	5	"SH-SY5Y: 12.9;WM-115: 25.7"	"Low region specificity"	"Detected in many"							"HPA049395, HPA053288"	Enhanced		Approved	"Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites"		NA	NA			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 62: Liver - Hemostasis"	"Cluster 17: WM-115 - Nervous system development"	"Cluster 2: Hepatocytes - Metabolism"	"Nucleoplasm, Plasma membrane, Actin filaments"	"Focal adhesion sites"	"HPA049395: AB_2680745, HPA053288: AB_2682102"	"unprognostic (7.92e-2)"	"unprognostic (8.87e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.90e-1)"	"unprognostic (8.95e-2)"	"unprognostic (1.06e-2)"	"unprognostic (2.35e-3)"	"unprognostic (9.91e-2)"	"unprognostic (3.53e-1)"	"unprognostic (1.19e-1)"	"unprognostic (2.44e-3)"	"unprognostic (8.43e-2)"	"unprognostic (2.83e-2)"	"unprognostic (8.01e-3)"	"unprognostic (7.12e-2)"	"unprognostic (2.11e-2)"	"unprognostic (2.47e-1)"	0.7	7.4	0.8	2.5	0.6	0.9	0.5	0.6	0.9	0.3	0.4	1.1	0.4	0.2	0.6	0.6	0.2	0.8	6.6	0.8	0.6	0.6	123.2	0.2	5.9	0.9	0.6	0.4	0.1	0.0	0.2	0.2	1.0	0.5	1.2	0.4	0.6	0.4	7.5	1.4	2.1	0.3	0.6	5.0	0.6	1.0	0.7	0.7	0.5	4.8	5.2	1.2	0.5	0.7	0.0	0.0	3.0	0.0	0.0	0.0	0.0	0.1	2.3	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.4	0.4	0.0	4.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.4	0.0	0.0	0.0	0.4	0.0	0.0	0.1	0.2	12.9	0.0	0.6	2.6	0.5	0.2	0.6	0.0	0.2	1.7	0.1	0.0	0.0	0.0	3.2	0.2	0.0	25.7	0.0	0.0	0.0	0.0	0.0	0.0	4.4	0.0	0.0	1.2	8.1	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.2	0.8	0.6	0.6	0.9	0.8	0.6	0.9	0.6	1.0	0.6	0.7	0.7	1.3	0.0	0.5	0.3	22.0	1.0	0.0	0.0	0.0	0.0	0.0	0.1	10.2	0.0	0.0	1.8	0.0	1.1	0.1	0.2	0.0	0.1	0.6	0.2	0.2	1.0	0.0	0.4	0.6	0.0	0.3	2.0	0.0	0.2	0.0	0.0	3.3	256.1	0.5	38.7	1.8	0.0	0.0	5.0	1.2	0.4	0.0	1.0	10.6	3.7	0.1	0.0	0.0	0.5	0.0	0.1	0.1	0.4	0.3	0.0	0.5	0.7	0.0	0.2	0.0	0.6	1.2	1.2	0.2	0.0	0.4	0.1	0.7	0.0	0.2	0.0
ABCG8	GBD4	ENSG00000143921	"ATP binding cassette subfamily G member 8"	Q9H221	2	43831942-43882988	"Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters"	"Lipid transport, Transport"	Translocase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	40	"intestine: 31.5;liver: 63.4"	"Group enriched"	"Detected in some"	4	"Hepatocytes: 32.0;Proximal enterocytes: 13.8"	"Cancer enriched"	"Detected in some"	30	"liver cancer: 21.6"	"Low region specificity"	"Detected in single"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in single"	44	"Hep G2: 5.3"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			HPA019556	Uncertain		Approved	Vesicles		NA	NA			"Cluster 11: Basophils - Unknown function"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 2: Hepatocytes - Metabolism"	Vesicles		"HPA019556: AB_1844444"	"unprognostic (1.99e-1)"	"unprognostic (4.49e-1)"	"unprognostic (3.22e-1)"	"unprognostic (1.37e-1)"	"unprognostic (3.09e-2)"	"unprognostic (2.43e-1)"	"unprognostic (1.99e-3)"	"unprognostic (1.27e-1)"	"unprognostic (6.28e-1)"	"unprognostic (6.14e-3)"	"unprognostic (4.69e-1)"	"unprognostic (1.76e-1)"	"unprognostic (2.68e-1)"	"unprognostic (7.86e-3)"	"unprognostic (5.03e-1)"		"unprognostic (1.50e-1)"	0.1	0.0	0.4	0.1	0.3	0.1	0.0	0.2	1.1	0.0	0.0	0.2	29.8	0.1	0.0	0.0	0.2	0.9	0.0	0.2	0.4	0.3	63.4	0.0	0.0	0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.1	0.1	0.0	0.0	0.0	0.1	31.5	0.0	0.0	0.1	0.3	0.0	0.7	0.0	0.1	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	5.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.4	0.3	0.2	1.1	0.2	0.4	0.3	0.1	0.4	0.0	0.7	0.7	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.2	2.8	0.6	1.8	0.0	0.0	0.1	0.0	1.9	0.1	0.0	0.2	0.7	0.6	0.0	2.7	3.6	0.0	0.0	0.2	0.0	0.5	0.0	0.2	0.4	32.0	0.0	0.0	2.8	0.8	0.0	0.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.5	0.4	0.0	5.0	0.0	0.0	0.0	13.8	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.2	0.1	1.2	0.0
ATP8B1	"ATPIC, BRIC, FIC1, PFIC, PFIC1"	ENSG00000081923	"ATPase phospholipid transporting 8B1"	O43520	18	57646426-57803315	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Hearing, Lipid transport, Transport"	Translocase	"Disease variant, Intrahepatic cholestasis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 76.2"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 279.7;Intestinal goblet cells: 180.5;Paneth cells: 116.7;Undifferentiated cells: 185.7;Urothelial cells: 119.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"fHDF/TERT166: 90.2;RT4: 168.1"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA018673, HPA018674"	Enhanced		Supported	"Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol"		NA	NA			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 37: Intestine - Unknown function"	"Cluster 15: RT4 - Unknown function"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Plasma membrane, Cytosol"	"Nucleoplasm, Nuclear bodies"	"HPA018673: AB_1845207, HPA018674: AB_1845208"	"unprognostic (1.83e-1)"	"unprognostic (1.32e-1)"	"prognostic favorable (2.60e-4)"	"unprognostic (8.81e-2)"	"unprognostic (1.32e-3)"	"unprognostic (2.06e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.02e-1)"	"unprognostic (9.62e-3)"	"unprognostic (1.97e-1)"	"unprognostic (3.30e-3)"	"unprognostic (4.55e-3)"	"prognostic favorable (6.35e-4)"	"unprognostic (1.88e-1)"	"unprognostic (2.22e-1)"	"unprognostic (3.25e-1)"	"unprognostic (8.60e-3)"	9.1	5.4	1.3	8.5	2.0	1.2	9.5	3.6	3.9	16.3	3.0	76.2	30.3	5.9	3.5	14.8	10.6	18.0	4.4	1.7	1.1	6.6	7.7	8.3	2.2	2.1	1.1	2.1	23.3	9.7	2.7	6.9	2.0	17.6	61.7	0.6	20.6	11.5	1.9	8.4	38.2	8.3	1.0	4.6	46.1	0.6	1.9	1.5	22.0	1.8	3.6	30.0	13.0	3.0	32.0	10.7	0.1	0.6	10.5	19.2	11.9	62.6	63.6	67.4	40.4	8.0	24.3	1.5	19.3	90.2	22.3	44.9	0.2	13.9	64.3	0.2	1.1	0.2	2.6	2.5	2.2	0.4	0.6	2.9	12.6	20.8	34.0	39.5	33.0	0.3	0.3	0.7	34.1	15.6	0.1	0.3	0.3	35.5	3.3	0.3	0.2	0.0	7.9	168.1	0.8	0.7	1.3	32.5	0.1	0.5	10.3	0.6	35.3	48.3	2.0	7.7	14.2	0.4	0.4	0.5	1.1	0.4	2.8	0.2	0.2	0.1	0.1	0.0	0.1	0.2	0.1	0.0	0.0	0.4	0.1	0.2	0.6	0.0	0.2	0.1	0.0	0.0	1.3	2.0	3.6	3.9	1.7	1.1	2.1	1.1	2.0	1.0	1.9	3.0	25.9	19.2	27.0	11.1	4.1	7.8	66.7	20.6	10.2	0.7	28.4	10.4	5.4	27.1	48.9	40.5	0.0	25.6	0.6	279.7	0.0	27.0	2.8	26.3	4.0	30.8	68.4	0.4	61.2	53.1	2.7	7.1	98.4	40.1	4.5	0.9	33.2	19.1	2.4	6.7	11.7	180.5	22.4	2.8	4.0	0.4	0.3	1.0	7.2	37.5	0.9	0.1	0.0	20.6	10.7	38.5	116.7	0.0	0.9	70.8	58.2	0.2	44.7	1.2	13.1	2.8	20.7	0.3	1.5	28.0	16.3	10.9	1.7	2.3	185.7	119.2
KRT18		ENSG00000111057	"Keratin 18"	P05783	12	52948871-52952906	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction"		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 3698.8;Ductal cells: 6583.8;Exocrine glandular cells: 4826.1;Extravillous trophoblasts: 5496.7;Pancreatic endocrine cells: 6071.5;Syncytiotrophoblasts: 7643.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in many"	7	"basophil: 76.7"	"Lineage enriched"	"Detected in many"	7	"granulocytes: 76.7"	"Cell line enhanced"	"Detected in many"		"A549: 5639.4;BEWO: 3818.0;CACO-2: 6249.4;CAPAN-2: 4576.4;MCF7: 8470.0;SK-BR-3: 4583.8"	"Low region specificity"	"Detected in many"			"Region enhanced"	"Detected in many"		"spinal cord: 12.1"	"CAB000008, CAB000030, HPA001605"	Enhanced		Supported	Cytosol		NA	NA		140000000	"Cluster 38: Basophils - Unknown function"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 1: Pancreatic cells - Digestion"	Cytosol		"CAB000008: , CAB000030: , HPA001605: AB_2666381"	"unprognostic (1.98e-1)"	"unprognostic (1.03e-1)"	"unprognostic (3.31e-1)"	"unprognostic (1.63e-2)"	"unprognostic (1.25e-1)"	"unprognostic (7.26e-3)"	"unprognostic (4.09e-3)"	"prognostic unfavorable (5.06e-4)"	"unprognostic (8.81e-2)"	"unprognostic (4.17e-1)"	"prognostic unfavorable (1.78e-4)"	"unprognostic (3.05e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.27e-1)"	"unprognostic (2.19e-1)"	"unprognostic (1.11e-2)"	"unprognostic (1.13e-2)"	170.3	29.0	2.6	77.5	1.4	1.5	209.8	5.3	1.6	243.5	34.8	424.1	324.3	27.8	226.0	118.4	193.5	180.6	38.3	2.2	6.9	247.2	519.5	177.8	8.6	26.1	4.3	16.4	570.2	79.5	251.9	474.5	30.3	183.3	492.3	0.6	323.4	129.5	2.1	44.5	370.7	23.4	2.5	28.5	289.9	8.3	13.9	10.3	244.1	1.4	27.8	199.7	62.2	2.5	2065.1	5639.4	1.1	7.9	0.7	1.1	3818.0	313.3	349.5	368.4	104.6	6249.4	4576.4	1.4	839.8	318.4	196.5	487.2	79.1	2228.5	217.9	2.6	138.2	19.4	865.7	1743.9	942.1	0.6	1.3	13.6	202.9	323.8	437.1	1046.9	399.0	3.4	511.4	0.2	0.3	8470.0	3.8	37.3	471.0	2740.1	457.9	3.0	0.3	236.1	1803.3	1144.9	65.6	3.7	512.7	4583.8	18.8	2696.0	2446.8	6.6	137.9	5.0	441.8	6.9	68.3	1.1	7.3	4.3	0.9	1.2	36.4	76.7	0.3	2.4	0.6	0.2	2.2	4.6	4.5	1.2	2.2	7.4	11.1	4.1	3.2	2.5	0.0	0.1	0.4	2.9	2.6	1.4	5.3	1.6	2.2	6.9	26.1	4.3	30.3	2.5	13.9	2.5	14.4	862.2	286.4	0.3	29.8	14.8	1605.7	912.1	447.3	0.1	814.6	615.6	5.3	1252.5	877.3	623.5	0.0	3698.8	14.2	1942.9	275.9	6583.8	1.0	462.3	60.3	77.8	642.3	15.4	0.0	4826.1	5496.7	203.5	971.5	742.4	48.9	51.2	57.1	610.9	308.3	1.7	0.0	2492.6	1969.3	9.8	13.8	3.8	10.5	28.3	208.1	1.0	41.5	6.2	0.0	0.0	0.0	6071.5	2164.1	0.0	13.7	1205.1	1912.3	718.5	500.8	0.6	0.0	0.6	298.6	2.7	26.0	395.7	6.7	7643.5	38.1	45.0	1635.0	1512.1
KRT8	"CARD2, CK8, CYK8, K2C8, K8, KO"	ENSG00000170421	"Keratin 8"	P05787	12	52897187-52949954	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Host-virus interaction"		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 1335.5;stomach 1: 800.1"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 4302.8;Ductal cells: 6037.3;Exocrine glandular cells: 5457.6;Extravillous trophoblasts: 5323.4;Pancreatic endocrine cells: 5278.1;Paneth cells: 4937.3;Proximal enterocytes: 6802.6;Syncytiotrophoblasts: 5268.8"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in some"		"plasmacytoid DC: 1.7"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"A549: 6130.6;BEWO: 3998.7;CACO-2: 7686.4;CAPAN-2: 4774.8;MCF7: 10521.8;SK-BR-3: 5126.4;T-47d: 4325.7"	"Low region specificity"	"Detected in many"			"Region enriched"	"Detected in all"	10	"spinal cord: 44.0"	"CAB000131, CAB001696, HPA049866"	Enhanced		Supported	"Intermediate filaments"		NA	NA		1700000000	"Cluster 15: NK-cells - Transcription"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 16: Pancreatic endocrine cells - Mixed function"	"Intermediate filaments"		"CAB000131: AB_2281144, CAB001696: , HPA049866: AB_2680923"	"unprognostic (5.72e-2)"	"unprognostic (2.29e-1)"	"unprognostic (2.49e-2)"	"unprognostic (1.52e-1)"	"unprognostic (2.76e-2)"	"unprognostic (4.86e-3)"	"unprognostic (3.10e-2)"	"unprognostic (2.52e-2)"	"unprognostic (1.92e-1)"	"unprognostic (4.58e-1)"	"prognostic unfavorable (1.51e-4)"	"unprognostic (8.99e-2)"	"unprognostic (2.08e-2)"	"unprognostic (2.83e-2)"	"unprognostic (3.18e-1)"	"unprognostic (3.68e-1)"	"unprognostic (1.19e-2)"	135.0	43.6	2.2	158.6	1.3	1.0	113.8	2.0	1.6	183.4	21.3	1079.2	1112.0	34.7	66.4	48.2	134.3	217.5	147.8	1.9	1.9	240.2	463.9	172.5	7.9	8.3	4.5	10.3	654.1	59.9	278.7	368.7	8.8	151.6	564.2	0.4	318.0	73.6	1.5	49.3	1335.5	50.6	0.4	16.3	800.1	7.6	4.9	47.6	237.5	0.3	13.8	209.0	36.7	1.7	2787.7	6130.6	0.2	7.8	0.7	3.2	3998.7	11.1	47.9	6.1	6.3	7686.4	4774.8	1.1	1130.2	14.7	6.9	947.1	17.6	752.6	5.9	4.6	130.8	4.3	1184.4	2234.2	212.8	1.2	2.4	9.5	12.6	14.8	50.8	419.9	17.0	1.0	484.7	1.7	0.1	10521.8	6.5	10.6	418.5	2740.6	132.8	3.8	2.2	15.2	1198.1	1354.5	129.9	5.0	1063.2	5126.4	7.8	1263.8	4325.7	10.5	18.8	5.7	443.4	9.3	10.0	1.6	7.0	7.6	3.3	1.7	13.4	1.3	0.1	0.2	0.2	0.2	0.1	0.1	0.1	0.1	0.7	0.2	0.1	0.1	0.4	0.5	0.1	1.7	0.1	0.2	2.2	1.3	2.0	1.6	1.9	1.9	8.3	4.5	8.8	0.4	4.9	1.7	7.7	400.6	176.5	0.3	26.9	6.0	1948.0	684.7	303.3	2.3	521.6	342.8	30.2	1069.5	734.8	491.1	0.0	2208.2	8.5	4302.8	297.4	6037.3	13.9	419.2	41.0	42.3	942.5	8.6	0.5	5457.6	5323.4	94.7	1740.1	557.1	76.3	88.0	24.3	310.9	252.2	1.7	0.5	2876.3	1625.5	9.9	7.2	69.9	8.1	22.2	131.6	0.0	55.0	3.4	1.0	1.0	0.3	5278.1	4937.3	1.9	6.6	994.7	6802.6	569.1	594.8	4.3	0.0	2.2	167.4	2.0	11.4	258.9	1.7	5268.8	33.4	13.4	2337.3	1542.5
LBR	"DHCR14B, TDRD18"	ENSG00000143815	"Lamin B receptor"	Q14739	1	225401502-225428925	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	"DNA-binding, Oxidoreductase, Receptor"	"Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Erythroid cells: 248.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA062236	Enhanced		Supported	"Nuclear membrane"		NA	Yes			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 6: Erythroid cells - Oxygen transport"	"Nuclear membrane"		"HPA062236: AB_2684721"	"unprognostic (2.57e-1)"	"unprognostic (1.57e-1)"	"unprognostic (2.14e-3)"	"unprognostic (1.32e-2)"	"unprognostic (7.96e-2)"	"unprognostic (1.98e-1)"	"prognostic unfavorable (7.30e-4)"	"unprognostic (3.60e-2)"	"unprognostic (1.11e-2)"	"unprognostic (3.43e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.99e-1)"	"unprognostic (6.42e-2)"	"unprognostic (2.08e-1)"	"unprognostic (5.45e-1)"	"unprognostic (8.32e-2)"	"unprognostic (2.78e-1)"	28.6	9.1	8.8	53.2	9.7	95.7	17.1	9.3	11.9	27.3	9.2	61.4	40.7	47.0	44.4	29.7	31.8	21.7	10.0	8.5	10.1	19.4	47.3	19.2	81.6	12.0	9.8	19.4	16.9	5.6	6.5	27.6	11.2	23.8	46.2	5.3	11.1	36.7	9.8	13.8	39.9	41.4	10.2	41.5	28.2	20.5	9.5	105.5	11.8	12.8	70.7	32.3	23.0	13.1	122.2	42.0	154.9	69.3	64.8	39.7	77.3	31.2	39.2	65.0	69.0	87.2	207.2	248.4	66.6	32.8	38.6	88.8	114.2	32.9	98.5	142.2	107.1	61.4	40.4	81.5	39.9	274.7	105.5	34.3	21.3	58.9	52.0	33.1	82.9	117.4	189.6	164.6	44.4	16.3	254.9	156.6	140.6	121.8	14.2	164.9	141.4	234.0	75.6	52.7	40.6	53.4	52.7	39.6	26.6	68.2	53.3	181.0	50.5	17.6	91.7	49.3	115.9	56.6	83.0	274.5	24.3	120.5	61.2	83.6	44.3	67.3	43.6	31.6	50.9	39.0	43.5	48.8	38.4	39.5	42.4	52.9	211.4	41.3	25.2	21.5	61.9	69.8	8.8	9.7	9.3	11.9	8.5	10.1	12.0	9.8	11.2	10.2	9.5	13.1	98.1	28.9	36.4	13.4	86.4	27.0	33.4	17.3	21.6	4.5	11.9	11.0	8.5	48.6	34.4	31.3	6.2	40.5	98.3	33.4	5.9	23.6	1.2	31.5	31.0	53.1	27.0	248.9	10.5	19.8	23.9	29.0	29.0	53.9	10.1	24.0	48.5	73.6	44.4	11.8	14.3	43.0	12.2	88.5	18.1	3.4	33.8	71.7	26.6	19.7	56.0	11.6	82.4	37.2	34.1	20.6	24.6	32.4	74.0	32.9	19.3	26.0	26.0	10.4	39.5	13.9	46.6	21.0	26.7	68.4	35.5	11.1	81.3	13.2	73.8	36.7
NR1H4	"FXR, HRR-1, HRR1, RIP14"	ENSG00000012504	"Nuclear receptor subfamily 1 group H member 4"	Q96RI1	12	100473708-100564414	"Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters"	"Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation"	"Activator, DNA-binding, Receptor, Repressor"	"Disease variant, FDA approved drug targets, Intrahepatic cholestasis"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 39.1;liver: 120.6"	"Cell type enhanced"	"Detected in some"		"Cholangiocytes: 92.9;Hepatocytes: 105.1;Proximal enterocytes: 331.0;Proximal tubular cells: 153.8"	"Group enriched"	"Detected in some"	11	"liver cancer: 18.7;renal cancer: 12.6"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	30	"Hep G2: 28.3;HHSteC: 14.1;RPTEC TERT1: 44.9"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA047699			Approved	Nucleoplasm		NA	NA				"Cluster 85: Liver - Metabolism"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 45: Enterocytes - Digestion"	Nucleoplasm		"HPA047699: AB_10965320"			"unprognostic (1.78e-1)"		"unprognostic (1.81e-1)"		"unprognostic (6.68e-2)"	"unprognostic (2.49e-1)"		"unprognostic (1.60e-1)"	"unprognostic (9.39e-2)"	"unprognostic (2.01e-1)"	"unprognostic (1.88e-2)"	"unprognostic (1.16e-1)"	"unprognostic (2.43e-1)"		"unprognostic (3.77e-3)"	0.2	22.6	0.1	1.4	0.1	0.4	1.0	0.5	0.4	0.2	1.8	8.3	29.6	0.1	0.1	0.2	0.2	12.6	0.4	0.2	0.1	28.2	120.6	0.4	0.3	0.1	0.1	14.0	3.1	0.0	1.4	0.0	0.1	0.3	1.6	0.3	0.3	0.0	0.3	0.5	39.1	0.8	0.0	0.4	0.5	0.7	0.2	0.1	0.3	0.1	0.2	6.5	0.1	0.5	0.0	0.9	0.1	0.3	0.0	0.1	0.4	0.0	0.0	0.0	0.0	0.1	0.2	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.3	28.3	14.1	0.1	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.2	0.1	0.0	0.6	0.1	0.0	0.0	44.9	0.4	0.2	0.0	0.0	0.1	0.1	0.0	0.0	0.2	0.0	0.0	0.2	0.1	0.0	0.1	0.1	0.2	0.0	0.3	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.5	0.4	0.2	0.1	0.1	0.1	0.1	0.0	0.2	0.5	0.0	0.0	0.0	0.3	1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	92.9	0.0	22.0	0.0	0.0	0.0	8.0	43.0	11.5	0.7	0.0	0.0	0.3	0.0	2.7	0.4	0.0	0.0	0.5	0.0	0.0	0.0	0.6	8.9	105.1	0.0	0.0	1.6	17.0	0.0	3.5	0.0	2.0	0.9	0.8	0.0	1.0	0.0	0.0	0.0	0.5	0.3	0.4	19.9	0.0	0.0	0.0	331.0	153.8	0.0	0.0	0.0	0.0	0.1	0.4	1.3	0.0	0.0	0.0	0.9	1.1	30.4	3.7
PNPLA3	"adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon"	ENSG00000100344	"Patatin like phospholipase domain containing 3"	Q9NST1	22	43923792-43964488	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism"	"Acyltransferase, Hydrolase, Transferase"	"Disease variant, Obesity"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	5	"liver: 31.0"	"Cell type enhanced"	"Detected in some"		"Bipolar cells: 35.9;Cone photoreceptor cells: 18.8;Hepatocytes: 42.3;Rod photoreceptor cells: 37.3"	"Cancer enhanced"	"Detected in many"		"liver cancer: 4.9"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"AF22: 16.7;LHCN-M2: 19.3"	"Region enhanced"	"Detected in many"		"cerebellum: 12.2"	"Not detected"	"Not detected"			HPA058058	Approved		Approved	Nucleoli,Mitochondria,Cytosol		NA	NA				"Cluster 85: Liver - Metabolism"	"Cluster 12: NES - Nervous system development"	"Cluster 9: Photoreceptor cells - Phototransduction"	Nucleoli	"Mitochondria, Cytosol"	"HPA058058: AB_2683590"	"unprognostic (4.74e-3)"	"unprognostic (4.52e-2)"	"unprognostic (1.76e-1)"	"unprognostic (2.31e-1)"	"unprognostic (1.36e-2)"	"unprognostic (1.89e-1)"	"unprognostic (8.93e-2)"	"unprognostic (1.02e-1)"	"unprognostic (2.63e-1)"	"unprognostic (2.93e-1)"	"unprognostic (2.33e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.39e-3)"	"unprognostic (2.52e-3)"	"unprognostic (5.91e-2)"	"unprognostic (2.02e-2)"	"unprognostic (1.01e-1)"	2.6	0.2	0.6	0.5	0.8	0.1	1.6	0.1	1.2	0.6	5.9	0.1	0.8	0.3	0.1	0.2	0.9	0.4	0.2	1.2	0.7	4.5	31.0	0.8	0.3	1.7	1.8	0.3	0.0	0.2	0.0	0.3	2.0	0.0	0.1	6.4	0.7	0.0	1.7	5.8	0.5	0.0	0.2	0.4	0.2	0.4	1.3	0.1	0.1	0.1	0.2	0.0	0.3	0.6	5.1	1.6	16.7	6.8	4.6	5.2	0.5	3.1	1.8	4.1	8.8	5.0	9.0	0.0	2.5	5.2	2.4	4.3	10.6	5.0	3.4	0.0	0.9	0.3	4.5	9.4	7.5	0.0	0.3	6.0	3.8	13.2	0.6	7.0	0.5	0.2	0.0	0.0	19.3	0.7	0.3	0.0	11.5	0.6	0.0	0.1	8.9	0.2	1.7	0.2	1.5	0.1	3.4	1.4	4.8	2.9	5.3	5.8	0.6	1.6	4.9	0.1	0.1	0.1	0.0	0.0	14.3	0.1	6.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.6	0.8	0.1	1.2	1.2	0.7	1.7	1.8	2.0	0.2	1.3	0.6	0.4	0.0	0.0	4.2	0.2	0.4	0.5	2.4	0.0	35.9	0.5	0.1	1.3	10.0	1.4	0.0	18.8	0.0	0.2	0.2	0.0	0.4	0.0	1.5	0.5	0.4	1.8	0.0	1.9	0.0	0.1	0.5	0.0	3.6	0.0	1.9	0.7	42.3	0.7	0.0	1.2	0.8	0.0	2.8	0.3	0.3	0.3	0.9	1.8	0.0	0.0	1.1	0.0	0.0	0.8	2.6	0.0	0.7	0.0	0.7	0.4	5.0	0.1	37.3	0.0	1.0	0.8	0.6	0.6	0.0	0.1	0.0	0.2	1.6	0.4	0.4
SP110	"IFI41, IFI75"	ENSG00000135899	"SP110 nuclear body protein"	Q9HB58	2	230165186-230225729	"Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Host-virus interaction, Transcription, Transcription regulation"	DNA-binding		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 53.7"	"Cell type enhanced"	"Detected in many"		"B-cells: 141.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"BJ hTERT+ SV40 Large T+ RasG12V: 99.3"					"Low region specificity"	"Detected in all"			HPA058554			Supported	Nucleoplasm		No	No			"Cluster 5: Granulocytes - Unknown function"	"Cluster 16: Immune cells - Immune response"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 57: B-cells - Immune response"	Nucleoplasm		"HPA058554: AB_2683754"	"unprognostic (9.72e-2)"	"unprognostic (1.15e-2)"	"unprognostic (5.02e-2)"	"unprognostic (8.33e-4)"	"unprognostic (2.93e-1)"	"unprognostic (1.80e-1)"	"unprognostic (6.65e-2)"	"unprognostic (9.44e-2)"	"unprognostic (9.68e-2)"	"unprognostic (1.46e-2)"	"unprognostic (4.11e-3)"	"unprognostic (2.55e-1)"	"prognostic unfavorable (1.17e-5)"	"unprognostic (2.38e-1)"	"unprognostic (2.66e-2)"	"unprognostic (2.99e-3)"	"unprognostic (9.50e-3)"	14.0	7.3	8.4	38.5	10.3	29.8	11.8	9.4	10.8	11.6	11.5	12.6	11.9	10.5	7.9	9.2	9.6	18.0	8.1	8.1	10.3	11.9	14.8	21.0	53.7	15.3	10.9	16.5	7.9	9.7	5.3	17.5	11.6	9.6	14.0	2.0	17.0	7.6	5.7	7.8	17.6	13.4	12.1	49.8	12.9	3.1	10.9	35.7	7.4	8.4	50.1	18.9	9.3	12.3	8.3	4.4	2.7	4.7	14.2	23.6	8.3	14.8	30.8	70.3	99.3	0.2	12.7	34.5	13.8	15.8	67.0	5.1	9.0	23.0	25.7	30.5	6.0	14.9	6.2	8.9	14.5	22.1	17.1	32.7	11.8	20.8	27.4	13.2	25.3	23.6	5.3	12.1	20.6	4.9	33.0	43.5	8.6	4.2	5.1	20.1	25.4	12.8	56.2	11.1	0.5	5.7	5.7	12.7	32.7	0.9	9.6	18.5	18.8	12.9	7.9	3.2	7.5	12.9	4.6	16.2	14.4	20.6	10.7	92.2	49.7	124.4	55.2	85.8	47.8	142.8	53.5	50.5	44.1	135.8	54.1	58.7	268.6	56.9	143.4	84.4	70.7	48.5	8.4	10.3	9.4	10.8	8.1	10.3	15.3	10.9	11.6	12.1	10.9	12.3	77.8	44.8	23.8	17.3	141.7	9.9	5.2	25.7	16.5	0.4	21.6	19.3	3.7	7.2	19.6	11.0	0.0	3.8	84.0	17.0	13.7	19.9	5.2	17.2	21.3	28.6	6.7	9.7	1.1	28.5	12.7	22.8	9.2	20.1	38.0	21.2	26.4	6.2	26.9	0.0	2.1	11.4	73.2	47.4	25.8	4.2	11.8	62.3	19.6	42.2	56.7	9.7	59.8	19.6	18.2	26.0	11.6	10.1	35.7	3.5	10.7	14.4	21.0	4.9	6.6	8.6	16.2	4.8	2.3	9.8	10.1	4.7	68.8	23.5	6.1	3.0
TJP2	"DFNA51, X104, ZO-2, ZO2"	ENSG00000119139	"Tight junction protein 2"	Q9UDY2	9	69121264-69274615	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Disease variant, Intrahepatic cholestasis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Bipolar cells: 212.4;Rod photoreceptor cells: 267.6;Urothelial cells: 244.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"non-classical monocyte: 2.2"	"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in many"		"A-431: 237.5"	"Low region specificity"	"Detected in all"							"HPA001813, CAB009228, HPA070714"	Supported		Enhanced	"Nucleoplasm,Plasma membrane,Cell Junctions"		NA	NA		580000	"Cluster 35: T-regs - Unknown function"	"Cluster 77: Retina - Visual perception"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 56: Bipolar cells - Visual perception"	"Plasma membrane, Cell Junctions"	Nucleoplasm	"CAB009228: AB_2203583, HPA001813: AB_1080764, HPA070714: AB_2732161"	"unprognostic (1.30e-1)"	"unprognostic (7.69e-2)"	"unprognostic (1.23e-3)"	"unprognostic (7.68e-2)"	"unprognostic (2.01e-1)"	"unprognostic (8.83e-3)"	"unprognostic (1.94e-2)"	"unprognostic (1.86e-1)"	"unprognostic (4.82e-2)"	"unprognostic (3.30e-2)"	"unprognostic (2.93e-3)"	"unprognostic (3.60e-1)"	"prognostic favorable (1.78e-14)"	"unprognostic (3.29e-2)"	"unprognostic (6.42e-2)"	"unprognostic (8.15e-3)"	"unprognostic (5.85e-2)"	44.4	14.9	35.1	11.6	45.3	12.0	30.2	44.5	42.6	16.9	25.7	39.0	54.4	19.8	13.1	45.8	23.8	24.4	35.8	38.0	45.4	44.7	64.8	47.6	9.7	52.6	39.9	37.0	21.9	57.9	5.3	18.4	52.6	24.8	35.1	122.0	37.1	21.9	14.1	35.0	49.6	16.1	55.0	5.7	58.3	32.1	39.9	32.5	44.9	15.1	23.1	55.3	22.3	66.3	237.5	6.4	24.4	25.8	92.9	90.3	108.5	37.3	26.7	54.9	29.0	31.8	106.6	33.0	37.0	20.3	31.4	158.3	33.2	79.3	75.9	115.3	20.7	34.5	22.5	165.2	28.9	13.8	59.1	71.3	65.2	43.1	32.4	19.6	143.6	9.9	19.7	24.7	34.3	36.0	5.5	2.3	49.5	194.5	50.0	23.1	26.9	2.9	192.0	194.2	8.3	14.9	13.3	111.2	3.4	55.7	37.0	7.9	196.3	44.3	48.3	32.4	38.6	23.0	5.2	0.9	48.0	19.6	16.1	0.0	0.3	0.0	0.0	0.9	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.1	0.0	2.2	0.1	0.8	0.1	35.1	45.3	44.5	42.6	38.0	45.4	52.6	39.9	52.6	55.0	39.9	66.3	2.9	44.8	22.8	76.4	2.3	65.1	79.1	26.3	4.6	212.4	4.6	1.3	38.5	40.0	33.1	3.7	35.5	27.9	2.7	74.4	0.0	32.5	3.5	7.1	1.7	36.4	11.5	10.5	10.1	24.3	25.6	15.5	64.2	9.9	5.7	0.2	27.5	104.9	5.6	18.5	13.4	45.0	36.7	14.6	28.9	6.7	29.2	8.2	28.4	22.5	9.0	111.1	1.0	21.6	82.5	44.2	65.8	13.9	5.2	115.4	73.4	1.9	51.3	267.6	0.0	4.9	13.1	19.6	18.0	40.6	64.1	43.2	3.2	0.2	50.3	244.5
UTP4	"CIRH1A, CIRHIN, FLJ14728, KIAA1988, NAIC, TEX292"	ENSG00000141076	"UTP4 small subunit processome component"	Q969X6	16	69131291-69231130	"Human disease related genes, Predicted intracellular proteins"	"Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation"		"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Proximal tubular cells: 100.0;Spermatogonia: 49.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"U-698: 398.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041139, HPA043542"	Approved		Supported	"Nucleoli fibrillar center"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 59: Non-specific - Translation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	"Nucleoli fibrillar center"		"HPA041139: AB_10961278, HPA043542: AB_2678542"	"unprognostic (1.82e-1)"	"unprognostic (2.11e-1)"	"unprognostic (1.48e-1)"	"unprognostic (1.89e-2)"	"unprognostic (6.16e-3)"	"prognostic unfavorable (9.05e-5)"	"prognostic unfavorable (8.18e-7)"	"unprognostic (1.31e-1)"	"unprognostic (4.76e-2)"	"prognostic favorable (2.88e-5)"	"unprognostic (2.12e-2)"	"unprognostic (4.45e-2)"	"unprognostic (2.32e-3)"	"unprognostic (9.57e-3)"	"unprognostic (2.12e-1)"	"unprognostic (1.33e-1)"	"unprognostic (3.20e-2)"	25.4	17.4	7.7	17.5	8.6	27.1	21.0	7.3	10.1	16.3	7.3	21.1	10.8	20.6	9.9	23.0	19.5	12.7	19.2	10.3	7.5	31.7	19.1	16.3	19.1	6.1	6.9	18.3	24.1	16.6	14.2	15.5	6.6	16.1	17.6	11.4	15.7	14.4	61.7	20.2	13.9	22.7	5.9	14.0	19.1	31.4	8.0	17.6	23.2	26.3	23.3	28.8	16.8	7.3	79.6	95.6	56.9	79.8	48.5	42.9	94.5	83.7	57.2	152.1	112.8	188.1	68.8	166.4	68.0	57.7	63.1	106.0	130.8	102.7	167.4	33.2	74.6	82.2	58.6	99.7	58.6	96.5	52.7	41.0	55.2	143.0	129.5	40.7	68.6	88.8	169.4	22.9	90.0	96.2	105.4	50.5	139.1	80.3	66.7	174.3	85.3	163.4	63.6	77.7	96.4	67.1	178.3	45.3	48.3	63.3	80.2	53.4	48.2	83.3	83.6	73.4	119.2	59.5	116.1	398.1	56.5	76.5	87.4	4.5	18.6	3.5	26.7	26.1	38.5	30.6	30.0	26.9	25.6	20.1	34.7	31.6	1.7	35.0	19.4	21.6	31.5	30.2	7.7	8.6	7.3	10.1	10.3	7.5	6.1	6.9	6.6	5.9	8.0	7.3	12.1	6.4	11.4	0.0	14.6	0.0	30.0	0.0	28.5	5.7	12.4	11.6	0.0	5.7	9.9	5.5	8.4	18.9	7.4	1.7	9.8	27.4	17.9	7.0	13.2	12.1	0.0	12.4	0.0	25.4	22.1	14.8	10.2	9.0	2.5	12.0	9.3	7.9	16.7	6.7	0.0	6.4	0.0	8.9	0.0	7.6	15.8	9.8	0.0	0.0	8.2	7.6	11.3	0.0	0.0	24.4	5.4	14.7	13.4	26.7	4.5	100.0	5.8	5.7	6.6	26.7	12.8	30.1	49.5	25.1	0.0	12.9	11.0	16.5	10.0	22.6
