[{"Gene":"ACP2","Gene synonym":["LAP"],"Ensembl":"ENSG00000134575","Gene description":"Acid phosphatase 2, lysosomal","Uniprot":["P11117"],"Chromosome":"11","Position":"47239302-47248906","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"89.3","Hofbauer cells":"113.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"69.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"69.9"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.2","Tissue RNA - adrenal gland [nTPM]":"36.6","Tissue RNA - amygdala [nTPM]":"17.3","Tissue RNA - appendix [nTPM]":"22.9","Tissue RNA - basal ganglia [nTPM]":"17.1","Tissue RNA - bone marrow [nTPM]":"6.4","Tissue RNA - breast [nTPM]":"21.8","Tissue RNA - cerebellum [nTPM]":"17.0","Tissue RNA - cerebral cortex [nTPM]":"18.5","Tissue RNA - cervix [nTPM]":"16.5","Tissue RNA - choroid plexus [nTPM]":"22.1","Tissue RNA - colon [nTPM]":"23.3","Tissue RNA - duodenum [nTPM]":"42.9","Tissue RNA - endometrium 1 [nTPM]":"15.8","Tissue RNA - epididymis [nTPM]":"29.8","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"19.6","Tissue RNA - heart muscle [nTPM]":"21.7","Tissue RNA - hippocampal formation [nTPM]":"19.8","Tissue RNA - hypothalamus [nTPM]":"26.0","Tissue RNA - kidney [nTPM]":"27.4","Tissue RNA - liver [nTPM]":"80.5","Tissue RNA - lung [nTPM]":"21.4","Tissue RNA - lymph node [nTPM]":"29.4","Tissue RNA - medulla oblongata [nTPM]":"20.8","Tissue RNA - midbrain [nTPM]":"19.6","Tissue RNA - ovary [nTPM]":"11.1","Tissue RNA - pancreas [nTPM]":"45.9","Tissue RNA - parathyroid gland [nTPM]":"21.3","Tissue RNA - pituitary gland [nTPM]":"21.3","Tissue RNA - placenta [nTPM]":"28.7","Tissue RNA - pons [nTPM]":"23.1","Tissue RNA - prostate [nTPM]":"25.4","Tissue RNA - rectum [nTPM]":"18.1","Tissue RNA - retina [nTPM]":"11.9","Tissue RNA - salivary gland [nTPM]":"50.3","Tissue RNA - seminal vesicle [nTPM]":"18.3","Tissue RNA - skeletal muscle [nTPM]":"14.0","Tissue RNA - skin 1 [nTPM]":"11.4","Tissue RNA - small intestine [nTPM]":"31.9","Tissue RNA - smooth muscle [nTPM]":"16.9","Tissue RNA - spinal cord [nTPM]":"16.9","Tissue RNA - spleen [nTPM]":"29.1","Tissue RNA - stomach 1 [nTPM]":"24.8","Tissue RNA - testis [nTPM]":"12.2","Tissue RNA - thalamus [nTPM]":"22.0","Tissue RNA - thymus [nTPM]":"13.7","Tissue RNA - thyroid gland [nTPM]":"19.3","Tissue RNA - tongue [nTPM]":"14.8","Tissue RNA - tonsil [nTPM]":"15.3","Tissue RNA - urinary bladder [nTPM]":"22.0","Tissue RNA - vagina [nTPM]":"13.1","Tissue RNA - white matter [nTPM]":"17.2","Cell RNA - A-431 [nTPM]":"16.5","Cell RNA - A549 [nTPM]":"33.5","Cell RNA - AF22 [nTPM]":"31.9","Cell RNA - AN3-CA [nTPM]":"28.2","Cell RNA - ASC diff [nTPM]":"28.1","Cell RNA - ASC TERT1 [nTPM]":"13.6","Cell RNA - BEWO [nTPM]":"24.4","Cell RNA - BJ [nTPM]":"26.6","Cell RNA - BJ hTERT+ [nTPM]":"47.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"49.4","Cell RNA - CACO-2 [nTPM]":"23.3","Cell RNA - CAPAN-2 [nTPM]":"26.3","Cell RNA - Daudi [nTPM]":"4.3","Cell RNA - EFO-21 [nTPM]":"21.9","Cell RNA - fHDF\/TERT166 [nTPM]":"34.2","Cell RNA - GAMG [nTPM]":"14.3","Cell RNA - HaCaT [nTPM]":"23.7","Cell RNA - HAP1 [nTPM]":"16.9","Cell RNA - HBEC3-KT [nTPM]":"24.6","Cell RNA - HBF TERT88 [nTPM]":"22.5","Cell RNA - HDLM-2 [nTPM]":"85.5","Cell RNA - HEK 293 [nTPM]":"29.1","Cell RNA - HEL [nTPM]":"11.1","Cell RNA - HeLa [nTPM]":"48.1","Cell RNA - Hep G2 [nTPM]":"24.6","Cell RNA - HHSteC [nTPM]":"38.4","Cell RNA - HL-60 [nTPM]":"16.4","Cell RNA - HMC-1 [nTPM]":"27.1","Cell RNA - HSkMC [nTPM]":"34.1","Cell RNA - hTCEpi [nTPM]":"15.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.6","Cell RNA - hTERT-HME1 [nTPM]":"14.5","Cell RNA - hTERT-RPE1 [nTPM]":"28.3","Cell RNA - HUVEC TERT2 [nTPM]":"34.9","Cell RNA - JURKAT [nTPM]":"14.1","Cell RNA - K-562 [nTPM]":"20.3","Cell RNA - Karpas-707 [nTPM]":"33.9","Cell RNA - LHCN-M2 [nTPM]":"31.5","Cell RNA - MCF7 [nTPM]":"26.8","Cell RNA - MOLT-4 [nTPM]":"13.4","Cell RNA - NB-4 [nTPM]":"14.2","Cell RNA - NTERA-2 [nTPM]":"21.5","Cell RNA - OE19 [nTPM]":"24.8","Cell RNA - PC-3 [nTPM]":"20.0","Cell RNA - REH [nTPM]":"10.8","Cell RNA - RH-30 [nTPM]":"43.1","Cell RNA - RPMI-8226 [nTPM]":"36.2","Cell RNA - RPTEC TERT1 [nTPM]":"34.9","Cell RNA - RT4 [nTPM]":"37.6","Cell RNA - SCLC-21H [nTPM]":"16.7","Cell RNA - SH-SY5Y [nTPM]":"26.0","Cell RNA - SiHa [nTPM]":"36.8","Cell RNA - SK-BR-3 [nTPM]":"80.1","Cell RNA - SK-MEL-30 [nTPM]":"19.2","Cell RNA - SuSa [nTPM]":"16.3","Cell RNA - T-47d [nTPM]":"49.0","Cell RNA - THP-1 [nTPM]":"14.0","Cell RNA - TIME [nTPM]":"21.0","Cell RNA - U-138 MG [nTPM]":"23.9","Cell RNA - U-2 OS [nTPM]":"19.8","Cell RNA - U-2197 [nTPM]":"31.4","Cell RNA - U-251 MG [nTPM]":"38.4","Cell RNA - U-266\/70 [nTPM]":"28.1","Cell RNA - U-266\/84 [nTPM]":"40.0","Cell RNA - U-698 [nTPM]":"3.6","Cell RNA - U-87 MG [nTPM]":"35.0","Cell RNA - U-937 [nTPM]":"8.2","Cell RNA - WM-115 [nTPM]":"37.6","Blood RNA - basophil [nTPM]":"12.5","Blood RNA - classical monocyte [nTPM]":"16.9","Blood RNA - eosinophil [nTPM]":"7.2","Blood RNA - gdT-cell [nTPM]":"12.3","Blood RNA - intermediate monocyte [nTPM]":"69.9","Blood RNA - MAIT T-cell [nTPM]":"9.4","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"7.6","Blood RNA - memory CD8 T-cell [nTPM]":"11.1","Blood RNA - myeloid DC [nTPM]":"15.1","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"6.6","Blood RNA - naive CD8 T-cell [nTPM]":"5.7","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"48.2","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"10.9","Brain RNA - amygdala [nTPM]":"17.3","Brain RNA - basal ganglia [nTPM]":"17.1","Brain RNA - cerebellum [nTPM]":"17.0","Brain RNA - cerebral cortex [nTPM]":"18.5","Brain RNA - hippocampal formation [nTPM]":"19.8","Brain RNA - hypothalamus [nTPM]":"26.0","Brain RNA - medulla oblongata [nTPM]":"20.8","Brain RNA - midbrain [nTPM]":"19.6","Brain RNA - pons [nTPM]":"23.1","Brain RNA - spinal cord [nTPM]":"16.9","Brain RNA - thalamus [nTPM]":"22.0","Brain RNA - white matter [nTPM]":"17.2","Single Cell Type RNA - Adipocytes [nTPM]":"13.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.6","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"5.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"42.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"29.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.3","Single Cell Type RNA - dendritic cells [nTPM]":"2.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"50.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.6","Single Cell Type RNA - Endothelial cells [nTPM]":"18.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"60.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"33.3","Single Cell Type RNA - Fibroblasts [nTPM]":"15.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"45.7","Single Cell Type RNA - Hepatocytes [nTPM]":"89.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"113.5","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.7","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"80.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.5","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"33.8","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"29.8","Single Cell Type RNA - Muller glia cells [nTPM]":"20.6","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.5","Single Cell Type RNA - Paneth cells [nTPM]":"29.5","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"21.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"55.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.5","Single Cell Type RNA - Spermatocytes [nTPM]":"11.8","Single Cell Type RNA - Spermatogonia [nTPM]":"19.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.3","Single Cell Type RNA - T-cells [nTPM]":"5.8","Single Cell Type RNA - Theca cells [nTPM]":"25.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.3","Single Cell Type RNA - Urothelial cells [nTPM]":"8.6"},{"Gene":"AGA","Gene synonym":["ASRG"],"Ensembl":"ENSG00000038002","Gene description":"Aspartylglucosaminidase","Uniprot":["P20933"],"Chromosome":"4","Position":"177430774-177442437","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"77.5","Karpas-707":"111.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031415","HPA031417"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"36000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031415":"AB_10603578","HPA031417":"AB_10670967"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.61e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.4","Tissue RNA - adrenal gland [nTPM]":"13.3","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"9.1","Tissue RNA - basal ganglia [nTPM]":"10.4","Tissue RNA - bone marrow [nTPM]":"15.4","Tissue RNA - breast [nTPM]":"21.1","Tissue RNA - cerebellum [nTPM]":"9.8","Tissue RNA - cerebral cortex [nTPM]":"12.0","Tissue RNA - cervix [nTPM]":"9.2","Tissue RNA - choroid plexus [nTPM]":"16.2","Tissue RNA - colon [nTPM]":"13.1","Tissue RNA - duodenum [nTPM]":"9.6","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"30.2","Tissue RNA - esophagus [nTPM]":"15.9","Tissue RNA - fallopian tube [nTPM]":"8.4","Tissue RNA - gallbladder [nTPM]":"13.1","Tissue RNA - heart muscle [nTPM]":"7.5","Tissue RNA - hippocampal formation [nTPM]":"8.4","Tissue RNA - hypothalamus [nTPM]":"9.9","Tissue RNA - kidney [nTPM]":"15.3","Tissue RNA - liver [nTPM]":"18.7","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"12.2","Tissue RNA - medulla oblongata [nTPM]":"11.4","Tissue RNA - midbrain [nTPM]":"9.1","Tissue RNA - ovary [nTPM]":"10.2","Tissue RNA - pancreas [nTPM]":"15.1","Tissue RNA - parathyroid gland [nTPM]":"17.1","Tissue RNA - pituitary gland [nTPM]":"6.1","Tissue RNA - placenta [nTPM]":"8.4","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"11.8","Tissue RNA - rectum [nTPM]":"13.1","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"14.9","Tissue RNA - seminal vesicle [nTPM]":"9.8","Tissue RNA - skeletal muscle [nTPM]":"9.0","Tissue RNA - skin 1 [nTPM]":"20.6","Tissue RNA - small intestine [nTPM]":"12.4","Tissue RNA - smooth muscle [nTPM]":"9.5","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"10.3","Tissue RNA - stomach 1 [nTPM]":"16.2","Tissue RNA - testis [nTPM]":"13.2","Tissue RNA - thalamus [nTPM]":"8.6","Tissue RNA - thymus [nTPM]":"11.1","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"15.6","Tissue RNA - urinary bladder [nTPM]":"10.9","Tissue RNA - vagina [nTPM]":"8.2","Tissue RNA - white matter [nTPM]":"13.7","Cell RNA - A-431 [nTPM]":"5.4","Cell RNA - A549 [nTPM]":"11.9","Cell RNA - AF22 [nTPM]":"13.3","Cell RNA - AN3-CA [nTPM]":"18.8","Cell RNA - ASC diff [nTPM]":"14.9","Cell RNA - ASC TERT1 [nTPM]":"13.2","Cell RNA - BEWO [nTPM]":"9.0","Cell RNA - BJ [nTPM]":"39.5","Cell RNA - BJ hTERT+ [nTPM]":"77.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.8","Cell RNA - CACO-2 [nTPM]":"6.2","Cell RNA - CAPAN-2 [nTPM]":"26.2","Cell RNA - Daudi [nTPM]":"26.9","Cell RNA - EFO-21 [nTPM]":"7.2","Cell RNA - fHDF\/TERT166 [nTPM]":"30.0","Cell RNA - GAMG [nTPM]":"9.7","Cell RNA - HaCaT [nTPM]":"6.5","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"13.0","Cell RNA - HBF TERT88 [nTPM]":"39.4","Cell RNA - HDLM-2 [nTPM]":"17.3","Cell RNA - HEK 293 [nTPM]":"7.5","Cell RNA - HEL [nTPM]":"11.2","Cell RNA - HeLa [nTPM]":"11.9","Cell RNA - Hep G2 [nTPM]":"17.3","Cell RNA - HHSteC [nTPM]":"10.0","Cell RNA - HL-60 [nTPM]":"19.6","Cell RNA - HMC-1 [nTPM]":"7.4","Cell RNA - HSkMC [nTPM]":"9.6","Cell RNA - hTCEpi [nTPM]":"22.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.7","Cell RNA - hTERT-HME1 [nTPM]":"6.5","Cell RNA - hTERT-RPE1 [nTPM]":"18.0","Cell RNA - HUVEC TERT2 [nTPM]":"18.7","Cell RNA - JURKAT [nTPM]":"11.4","Cell RNA - K-562 [nTPM]":"10.3","Cell RNA - Karpas-707 [nTPM]":"111.6","Cell RNA - LHCN-M2 [nTPM]":"8.0","Cell RNA - MCF7 [nTPM]":"14.6","Cell RNA - MOLT-4 [nTPM]":"15.9","Cell RNA - NB-4 [nTPM]":"12.0","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"10.5","Cell RNA - PC-3 [nTPM]":"12.2","Cell RNA - REH [nTPM]":"5.0","Cell RNA - RH-30 [nTPM]":"5.4","Cell RNA - RPMI-8226 [nTPM]":"4.0","Cell RNA - RPTEC TERT1 [nTPM]":"20.5","Cell RNA - RT4 [nTPM]":"12.9","Cell RNA - SCLC-21H [nTPM]":"7.3","Cell RNA - SH-SY5Y [nTPM]":"16.4","Cell RNA - SiHa [nTPM]":"11.9","Cell RNA - SK-BR-3 [nTPM]":"10.3","Cell RNA - SK-MEL-30 [nTPM]":"32.2","Cell RNA - SuSa [nTPM]":"9.9","Cell RNA - T-47d [nTPM]":"23.3","Cell RNA - THP-1 [nTPM]":"39.8","Cell RNA - TIME [nTPM]":"6.1","Cell RNA - U-138 MG [nTPM]":"13.9","Cell RNA - U-2 OS [nTPM]":"12.3","Cell RNA - U-2197 [nTPM]":"6.6","Cell RNA - U-251 MG [nTPM]":"15.2","Cell RNA - U-266\/70 [nTPM]":"21.2","Cell RNA - U-266\/84 [nTPM]":"17.4","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"22.3","Cell RNA - U-937 [nTPM]":"22.0","Cell RNA - WM-115 [nTPM]":"16.0","Blood RNA - basophil [nTPM]":"26.4","Blood RNA - classical monocyte [nTPM]":"15.3","Blood RNA - eosinophil [nTPM]":"23.9","Blood RNA - gdT-cell [nTPM]":"15.6","Blood RNA - intermediate monocyte [nTPM]":"27.5","Blood RNA - MAIT T-cell [nTPM]":"17.9","Blood RNA - memory B-cell [nTPM]":"13.9","Blood RNA - memory CD4 T-cell [nTPM]":"16.6","Blood RNA - memory CD8 T-cell [nTPM]":"18.8","Blood RNA - myeloid DC [nTPM]":"14.8","Blood RNA - naive B-cell [nTPM]":"12.9","Blood RNA - naive CD4 T-cell [nTPM]":"14.8","Blood RNA - naive CD8 T-cell [nTPM]":"21.3","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"12.7","Blood RNA - non-classical monocyte [nTPM]":"35.8","Blood RNA - plasmacytoid DC [nTPM]":"15.8","Blood RNA - T-reg [nTPM]":"17.8","Blood RNA - total PBMC [nTPM]":"15.1","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"10.4","Brain RNA - cerebellum [nTPM]":"9.8","Brain RNA - cerebral cortex [nTPM]":"12.0","Brain RNA - hippocampal formation [nTPM]":"8.4","Brain RNA - hypothalamus [nTPM]":"9.9","Brain RNA - medulla oblongata [nTPM]":"11.4","Brain RNA - midbrain [nTPM]":"9.1","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"8.6","Brain RNA - white matter [nTPM]":"13.7","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.5","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"20.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"3.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"21.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.3","Single Cell Type RNA - dendritic cells [nTPM]":"17.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"28.2","Single Cell Type RNA - Early spermatids [nTPM]":"13.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.5","Single Cell Type RNA - Endothelial cells [nTPM]":"10.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.0","Single Cell Type RNA - Fibroblasts [nTPM]":"16.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.5","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"23.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.1","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.2","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"15.4","Single Cell Type RNA - Langerhans cells [nTPM]":"23.3","Single Cell Type RNA - Late spermatids [nTPM]":"9.2","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"15.9","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"23.8","Single Cell Type RNA - Muller glia cells [nTPM]":"19.1","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.4","Single Cell Type RNA - Paneth cells [nTPM]":"9.1","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"48.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.1","Single Cell Type RNA - Spermatocytes [nTPM]":"35.8","Single Cell Type RNA - Spermatogonia [nTPM]":"36.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.7","Single Cell Type RNA - T-cells [nTPM]":"22.5","Single Cell Type RNA - Theca cells [nTPM]":"14.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.6","Single Cell Type RNA - Urothelial cells [nTPM]":"17.7"},{"Gene":"ARSA","Gene synonym":[],"Ensembl":"ENSG00000100299","Gene description":"Arylsulfatase A","Uniprot":["P15289"],"Chromosome":"22","Position":"50622754-50628173","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Ichthyosis","Leukodystrophy","Metachromatic leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"127.5","Plasma cells":"132.0","Proximal enterocytes":"93.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"80.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005554","CAB025183"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5600000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB025183":null,"HPA005554":"AB_1078220"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.96e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-3"},"Tissue RNA - adipose tissue [nTPM]":"28.8","Tissue RNA - adrenal gland [nTPM]":"25.1","Tissue RNA - amygdala [nTPM]":"14.4","Tissue RNA - appendix [nTPM]":"15.6","Tissue RNA - basal ganglia [nTPM]":"18.0","Tissue RNA - bone marrow [nTPM]":"18.4","Tissue RNA - breast [nTPM]":"27.2","Tissue RNA - cerebellum [nTPM]":"16.8","Tissue RNA - cerebral cortex [nTPM]":"21.8","Tissue RNA - cervix [nTPM]":"21.3","Tissue RNA - choroid plexus [nTPM]":"27.5","Tissue RNA - colon [nTPM]":"31.3","Tissue RNA - duodenum [nTPM]":"30.8","Tissue RNA - endometrium 1 [nTPM]":"22.4","Tissue RNA - epididymis [nTPM]":"8.6","Tissue RNA - esophagus [nTPM]":"28.1","Tissue RNA - fallopian tube [nTPM]":"25.1","Tissue RNA - gallbladder [nTPM]":"15.7","Tissue RNA - heart muscle [nTPM]":"33.0","Tissue RNA - hippocampal formation [nTPM]":"14.9","Tissue RNA - hypothalamus [nTPM]":"15.2","Tissue RNA - kidney [nTPM]":"31.4","Tissue RNA - liver [nTPM]":"42.8","Tissue RNA - lung [nTPM]":"29.1","Tissue RNA - lymph node [nTPM]":"19.8","Tissue RNA - medulla oblongata [nTPM]":"20.0","Tissue RNA - midbrain [nTPM]":"15.9","Tissue RNA - ovary [nTPM]":"11.3","Tissue RNA - pancreas [nTPM]":"46.7","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"34.7","Tissue RNA - placenta [nTPM]":"10.9","Tissue RNA - pons [nTPM]":"19.1","Tissue RNA - prostate [nTPM]":"28.9","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"39.6","Tissue RNA - seminal vesicle [nTPM]":"16.2","Tissue RNA - skeletal muscle [nTPM]":"25.3","Tissue RNA - skin 1 [nTPM]":"17.5","Tissue RNA - small intestine [nTPM]":"33.8","Tissue RNA - smooth muscle [nTPM]":"6.5","Tissue RNA - spinal cord [nTPM]":"16.3","Tissue RNA - spleen [nTPM]":"44.5","Tissue RNA - stomach 1 [nTPM]":"30.3","Tissue RNA - testis [nTPM]":"54.0","Tissue RNA - thalamus [nTPM]":"19.4","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"32.3","Tissue RNA - tongue [nTPM]":"5.1","Tissue RNA - tonsil [nTPM]":"9.5","Tissue RNA - urinary bladder [nTPM]":"23.9","Tissue RNA - vagina [nTPM]":"24.7","Tissue RNA - white matter [nTPM]":"21.0","Cell RNA - A-431 [nTPM]":"8.5","Cell RNA - A549 [nTPM]":"11.0","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"10.9","Cell RNA - ASC diff [nTPM]":"41.8","Cell RNA - ASC TERT1 [nTPM]":"21.8","Cell RNA - BEWO [nTPM]":"13.5","Cell RNA - BJ [nTPM]":"13.0","Cell RNA - BJ hTERT+ [nTPM]":"15.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.3","Cell RNA - CACO-2 [nTPM]":"3.3","Cell RNA - CAPAN-2 [nTPM]":"12.9","Cell RNA - Daudi [nTPM]":"5.3","Cell RNA - EFO-21 [nTPM]":"8.2","Cell RNA - fHDF\/TERT166 [nTPM]":"22.9","Cell RNA - GAMG [nTPM]":"10.8","Cell RNA - HaCaT [nTPM]":"12.8","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"12.3","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"2.7","Cell RNA - HEK 293 [nTPM]":"8.0","Cell RNA - HEL [nTPM]":"3.4","Cell RNA - HeLa [nTPM]":"14.3","Cell RNA - Hep G2 [nTPM]":"12.5","Cell RNA - HHSteC [nTPM]":"28.3","Cell RNA - HL-60 [nTPM]":"5.2","Cell RNA - HMC-1 [nTPM]":"32.7","Cell RNA - HSkMC [nTPM]":"26.0","Cell RNA - hTCEpi [nTPM]":"24.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.5","Cell RNA - hTERT-HME1 [nTPM]":"6.3","Cell RNA - hTERT-RPE1 [nTPM]":"19.9","Cell RNA - HUVEC TERT2 [nTPM]":"12.8","Cell RNA - JURKAT [nTPM]":"11.5","Cell RNA - K-562 [nTPM]":"3.5","Cell RNA - Karpas-707 [nTPM]":"80.4","Cell RNA - LHCN-M2 [nTPM]":"12.1","Cell RNA - MCF7 [nTPM]":"9.6","Cell RNA - MOLT-4 [nTPM]":"4.6","Cell RNA - NB-4 [nTPM]":"5.8","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"9.0","Cell RNA - PC-3 [nTPM]":"11.2","Cell RNA - REH [nTPM]":"4.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"26.7","Cell RNA - RPTEC TERT1 [nTPM]":"9.9","Cell RNA - RT4 [nTPM]":"13.5","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"8.2","Cell RNA - SiHa [nTPM]":"18.2","Cell RNA - SK-BR-3 [nTPM]":"17.2","Cell RNA - SK-MEL-30 [nTPM]":"10.1","Cell RNA - SuSa [nTPM]":"5.1","Cell RNA - T-47d [nTPM]":"7.7","Cell RNA - THP-1 [nTPM]":"6.6","Cell RNA - TIME [nTPM]":"22.1","Cell RNA - U-138 MG [nTPM]":"3.8","Cell RNA - U-2 OS [nTPM]":"15.1","Cell RNA - U-2197 [nTPM]":"14.9","Cell RNA - U-251 MG [nTPM]":"4.1","Cell RNA - U-266\/70 [nTPM]":"18.4","Cell RNA - U-266\/84 [nTPM]":"1.9","Cell RNA - U-698 [nTPM]":"4.5","Cell RNA - U-87 MG [nTPM]":"11.7","Cell RNA - U-937 [nTPM]":"4.3","Cell RNA - WM-115 [nTPM]":"13.6","Blood RNA - basophil [nTPM]":"10.4","Blood RNA - classical monocyte [nTPM]":"27.7","Blood RNA - eosinophil [nTPM]":"36.1","Blood RNA - gdT-cell [nTPM]":"17.3","Blood RNA - intermediate monocyte [nTPM]":"33.3","Blood RNA - MAIT T-cell [nTPM]":"15.1","Blood RNA - memory B-cell [nTPM]":"10.4","Blood RNA - memory CD4 T-cell [nTPM]":"12.4","Blood RNA - memory CD8 T-cell [nTPM]":"14.2","Blood RNA - myeloid DC [nTPM]":"22.7","Blood RNA - naive B-cell [nTPM]":"12.5","Blood RNA - naive CD4 T-cell [nTPM]":"7.3","Blood RNA - naive CD8 T-cell [nTPM]":"10.0","Blood RNA - neutrophil [nTPM]":"60.4","Blood RNA - NK-cell [nTPM]":"8.9","Blood RNA - non-classical monocyte [nTPM]":"43.2","Blood RNA - plasmacytoid DC [nTPM]":"32.1","Blood RNA - T-reg [nTPM]":"18.2","Blood RNA - total PBMC [nTPM]":"16.3","Brain RNA - amygdala [nTPM]":"14.4","Brain RNA - basal ganglia [nTPM]":"18.0","Brain RNA - cerebellum [nTPM]":"16.8","Brain RNA - cerebral cortex [nTPM]":"21.8","Brain RNA - hippocampal formation [nTPM]":"14.9","Brain RNA - hypothalamus [nTPM]":"15.2","Brain RNA - medulla oblongata [nTPM]":"20.0","Brain RNA - midbrain [nTPM]":"15.9","Brain RNA - pons [nTPM]":"19.1","Brain RNA - spinal cord [nTPM]":"16.3","Brain RNA - thalamus [nTPM]":"19.4","Brain RNA - white matter [nTPM]":"21.0","Single Cell Type RNA - Adipocytes [nTPM]":"22.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.9","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"22.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"5.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"15.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.5","Single Cell Type RNA - dendritic cells [nTPM]":"14.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"85.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"29.4","Single Cell Type RNA - Early spermatids [nTPM]":"62.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.3","Single Cell Type RNA - Endothelial cells [nTPM]":"13.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.7","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.9","Single Cell Type RNA - Fibroblasts [nTPM]":"19.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.3","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"15.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"28.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.8","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.6","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"29.0","Single Cell Type RNA - Langerhans cells [nTPM]":"9.5","Single Cell Type RNA - Late spermatids [nTPM]":"127.5","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"29.2","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"28.7","Single Cell Type RNA - Muller glia cells [nTPM]":"10.3","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.2","Single Cell Type RNA - Paneth cells [nTPM]":"75.2","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"132.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"93.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.9","Single Cell Type RNA - Spermatocytes [nTPM]":"48.3","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.3","Single Cell Type RNA - T-cells [nTPM]":"17.2","Single Cell Type RNA - Theca cells [nTPM]":"7.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.0","Single Cell Type RNA - Urothelial cells [nTPM]":"16.1"},{"Gene":"ARSB","Gene synonym":[],"Ensembl":"ENSG00000113273","Gene description":"Arylsulfatase B","Uniprot":["P15848"],"Chromosome":"5","Position":"78777209-78986087","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Ichthyosis","Leukodystrophy","Metachromatic leukodystrophy","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"40.8","Excitatory neurons":"37.4","Inhibitory neurons":"42.5","Microglial cells":"40.3","Oligodendrocyte precursor cells":"71.4","Oligodendrocytes":"56.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"25.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"7.8","granulocytes":"25.6","monocytes":"8.3"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037770","HPA037771"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA037770":"AB_10671719","HPA037771":"AB_10671720"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.42e-4"},"Tissue RNA - adipose tissue [nTPM]":"6.9","Tissue RNA - adrenal gland [nTPM]":"4.5","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"8.1","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"8.1","Tissue RNA - breast [nTPM]":"2.6","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"5.5","Tissue RNA - duodenum [nTPM]":"3.1","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"2.9","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"8.3","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"21.3","Tissue RNA - liver [nTPM]":"7.6","Tissue RNA - lung [nTPM]":"7.0","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"5.3","Tissue RNA - ovary [nTPM]":"2.2","Tissue RNA - pancreas [nTPM]":"4.6","Tissue RNA - parathyroid gland [nTPM]":"6.6","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"11.5","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"6.7","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"3.8","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"14.1","Tissue RNA - spinal cord [nTPM]":"4.3","Tissue RNA - spleen [nTPM]":"5.2","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"4.2","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"8.0","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"5.0","Cell RNA - A549 [nTPM]":"11.3","Cell RNA - AF22 [nTPM]":"18.6","Cell RNA - AN3-CA [nTPM]":"6.3","Cell RNA - ASC diff [nTPM]":"41.9","Cell RNA - ASC TERT1 [nTPM]":"16.4","Cell RNA - BEWO [nTPM]":"16.7","Cell RNA - BJ [nTPM]":"29.2","Cell RNA - BJ hTERT+ [nTPM]":"23.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.0","Cell RNA - CACO-2 [nTPM]":"9.9","Cell RNA - CAPAN-2 [nTPM]":"8.4","Cell RNA - Daudi [nTPM]":"6.5","Cell RNA - EFO-21 [nTPM]":"31.5","Cell RNA - fHDF\/TERT166 [nTPM]":"25.5","Cell RNA - GAMG [nTPM]":"29.0","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"7.0","Cell RNA - HBEC3-KT [nTPM]":"7.4","Cell RNA - HBF TERT88 [nTPM]":"18.5","Cell RNA - HDLM-2 [nTPM]":"55.6","Cell RNA - HEK 293 [nTPM]":"6.2","Cell RNA - HEL [nTPM]":"9.2","Cell RNA - HeLa [nTPM]":"11.2","Cell RNA - Hep G2 [nTPM]":"40.1","Cell RNA - HHSteC [nTPM]":"9.7","Cell RNA - HL-60 [nTPM]":"10.5","Cell RNA - HMC-1 [nTPM]":"10.4","Cell RNA - HSkMC [nTPM]":"19.4","Cell RNA - hTCEpi [nTPM]":"2.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.7","Cell RNA - hTERT-HME1 [nTPM]":"6.5","Cell RNA - hTERT-RPE1 [nTPM]":"15.6","Cell RNA - HUVEC TERT2 [nTPM]":"22.4","Cell RNA - JURKAT [nTPM]":"3.9","Cell RNA - K-562 [nTPM]":"2.0","Cell RNA - Karpas-707 [nTPM]":"12.9","Cell RNA - LHCN-M2 [nTPM]":"19.6","Cell RNA - MCF7 [nTPM]":"9.2","Cell RNA - MOLT-4 [nTPM]":"5.8","Cell RNA - NB-4 [nTPM]":"19.3","Cell RNA - NTERA-2 [nTPM]":"5.6","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"7.7","Cell RNA - RH-30 [nTPM]":"10.9","Cell RNA - RPMI-8226 [nTPM]":"5.9","Cell RNA - RPTEC TERT1 [nTPM]":"12.0","Cell RNA - RT4 [nTPM]":"6.2","Cell RNA - SCLC-21H [nTPM]":"6.8","Cell RNA - SH-SY5Y [nTPM]":"15.9","Cell RNA - SiHa [nTPM]":"20.3","Cell RNA - SK-BR-3 [nTPM]":"6.2","Cell RNA - SK-MEL-30 [nTPM]":"12.1","Cell RNA - SuSa [nTPM]":"12.7","Cell RNA - T-47d [nTPM]":"6.9","Cell RNA - THP-1 [nTPM]":"26.2","Cell RNA - TIME [nTPM]":"16.2","Cell RNA - U-138 MG [nTPM]":"17.5","Cell RNA - U-2 OS [nTPM]":"10.4","Cell RNA - U-2197 [nTPM]":"7.6","Cell RNA - U-251 MG [nTPM]":"26.4","Cell RNA - U-266\/70 [nTPM]":"14.8","Cell RNA - U-266\/84 [nTPM]":"28.0","Cell RNA - U-698 [nTPM]":"7.2","Cell RNA - U-87 MG [nTPM]":"21.6","Cell RNA - U-937 [nTPM]":"21.4","Cell RNA - WM-115 [nTPM]":"40.3","Blood RNA - basophil [nTPM]":"19.0","Blood RNA - classical monocyte [nTPM]":"8.3","Blood RNA - eosinophil [nTPM]":"25.6","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"6.7","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"2.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"7.8","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"4.6","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"5.6","Blood RNA - plasmacytoid DC [nTPM]":"5.7","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"2.7","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"5.3","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"4.3","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"40.8","Single Cell Type RNA - B-cells [nTPM]":"5.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - dendritic cells [nTPM]":"5.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"16.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"3.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.7","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"25.2","Single Cell Type RNA - Langerhans cells [nTPM]":"14.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"15.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"16.1","Single Cell Type RNA - Muller glia cells [nTPM]":"3.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"71.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"56.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"3.4","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"ASAH1","Gene synonym":["AC","ACDase","ASAH","FLJ21558","PHP32"],"Ensembl":"ENSG00000104763","Gene description":"N-acylsphingosine amidohydrolase 1","Uniprot":["Q13510"],"Chromosome":"8","Position":"18055992-18084998","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"573.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"777.0","Hofbauer cells":"921.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"392.8","SK-MEL-30":"590.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005468"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"400000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA005468":"AB_1845062"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.08e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-3"},"Tissue RNA - adipose tissue [nTPM]":"214.3","Tissue RNA - adrenal gland [nTPM]":"71.9","Tissue RNA - amygdala [nTPM]":"50.1","Tissue RNA - appendix [nTPM]":"51.6","Tissue RNA - basal ganglia [nTPM]":"51.5","Tissue RNA - bone marrow [nTPM]":"107.7","Tissue RNA - breast [nTPM]":"95.8","Tissue RNA - cerebellum [nTPM]":"62.1","Tissue RNA - cerebral cortex [nTPM]":"50.8","Tissue RNA - cervix [nTPM]":"98.5","Tissue RNA - choroid plexus [nTPM]":"62.6","Tissue RNA - colon [nTPM]":"84.3","Tissue RNA - duodenum [nTPM]":"54.7","Tissue RNA - endometrium 1 [nTPM]":"55.8","Tissue RNA - epididymis [nTPM]":"131.5","Tissue RNA - esophagus [nTPM]":"73.2","Tissue RNA - fallopian tube [nTPM]":"70.4","Tissue RNA - gallbladder [nTPM]":"99.1","Tissue RNA - heart muscle [nTPM]":"573.9","Tissue RNA - hippocampal formation [nTPM]":"49.9","Tissue RNA - hypothalamus [nTPM]":"66.2","Tissue RNA - kidney [nTPM]":"204.0","Tissue RNA - liver [nTPM]":"60.9","Tissue RNA - lung [nTPM]":"190.3","Tissue RNA - lymph node [nTPM]":"65.9","Tissue RNA - medulla oblongata [nTPM]":"66.0","Tissue RNA - midbrain [nTPM]":"59.4","Tissue RNA - ovary [nTPM]":"50.1","Tissue RNA - pancreas [nTPM]":"49.6","Tissue RNA - parathyroid gland [nTPM]":"117.8","Tissue RNA - pituitary gland [nTPM]":"83.6","Tissue RNA - placenta [nTPM]":"121.5","Tissue RNA - pons [nTPM]":"69.0","Tissue RNA - prostate [nTPM]":"84.3","Tissue RNA - rectum [nTPM]":"87.0","Tissue RNA - retina [nTPM]":"79.5","Tissue RNA - salivary gland [nTPM]":"66.6","Tissue RNA - seminal vesicle [nTPM]":"77.9","Tissue RNA - skeletal muscle [nTPM]":"66.0","Tissue RNA - skin 1 [nTPM]":"52.6","Tissue RNA - small intestine [nTPM]":"56.8","Tissue RNA - smooth muscle [nTPM]":"61.7","Tissue RNA - spinal cord [nTPM]":"66.3","Tissue RNA - spleen [nTPM]":"85.4","Tissue RNA - stomach 1 [nTPM]":"61.2","Tissue RNA - testis [nTPM]":"18.2","Tissue RNA - thalamus [nTPM]":"59.1","Tissue RNA - thymus [nTPM]":"26.0","Tissue RNA - thyroid gland [nTPM]":"325.5","Tissue RNA - tongue [nTPM]":"70.7","Tissue RNA - tonsil [nTPM]":"57.7","Tissue RNA - urinary bladder [nTPM]":"112.8","Tissue RNA - vagina [nTPM]":"54.8","Tissue RNA - white matter [nTPM]":"102.2","Cell RNA - A-431 [nTPM]":"48.1","Cell RNA - A549 [nTPM]":"66.4","Cell RNA - AF22 [nTPM]":"25.9","Cell RNA - AN3-CA [nTPM]":"63.3","Cell RNA - ASC diff [nTPM]":"392.8","Cell RNA - ASC TERT1 [nTPM]":"46.0","Cell RNA - BEWO [nTPM]":"39.2","Cell RNA - BJ [nTPM]":"48.2","Cell RNA - BJ hTERT+ [nTPM]":"67.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.0","Cell RNA - CACO-2 [nTPM]":"35.4","Cell RNA - CAPAN-2 [nTPM]":"66.1","Cell RNA - Daudi [nTPM]":"30.2","Cell RNA - EFO-21 [nTPM]":"60.3","Cell RNA - fHDF\/TERT166 [nTPM]":"54.5","Cell RNA - GAMG [nTPM]":"159.1","Cell RNA - HaCaT [nTPM]":"62.6","Cell RNA - HAP1 [nTPM]":"15.0","Cell RNA - HBEC3-KT [nTPM]":"25.3","Cell RNA - HBF TERT88 [nTPM]":"28.4","Cell RNA - HDLM-2 [nTPM]":"22.9","Cell RNA - HEK 293 [nTPM]":"38.9","Cell RNA - HEL [nTPM]":"134.4","Cell RNA - HeLa [nTPM]":"46.7","Cell RNA - Hep G2 [nTPM]":"96.7","Cell RNA - HHSteC [nTPM]":"107.5","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"140.7","Cell RNA - HSkMC [nTPM]":"100.2","Cell RNA - hTCEpi [nTPM]":"86.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.6","Cell RNA - hTERT-HME1 [nTPM]":"22.9","Cell RNA - hTERT-RPE1 [nTPM]":"53.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.2","Cell RNA - JURKAT [nTPM]":"50.6","Cell RNA - K-562 [nTPM]":"24.3","Cell RNA - Karpas-707 [nTPM]":"61.7","Cell RNA - LHCN-M2 [nTPM]":"67.9","Cell RNA - MCF7 [nTPM]":"46.0","Cell RNA - MOLT-4 [nTPM]":"15.5","Cell RNA - NB-4 [nTPM]":"48.3","Cell RNA - NTERA-2 [nTPM]":"30.3","Cell RNA - OE19 [nTPM]":"105.2","Cell RNA - PC-3 [nTPM]":"40.5","Cell RNA - REH [nTPM]":"19.4","Cell RNA - RH-30 [nTPM]":"25.5","Cell RNA - RPMI-8226 [nTPM]":"41.4","Cell RNA - RPTEC TERT1 [nTPM]":"112.0","Cell RNA - RT4 [nTPM]":"273.0","Cell RNA - SCLC-21H [nTPM]":"40.4","Cell RNA - SH-SY5Y [nTPM]":"55.0","Cell RNA - SiHa [nTPM]":"43.8","Cell RNA - SK-BR-3 [nTPM]":"145.2","Cell RNA - SK-MEL-30 [nTPM]":"590.5","Cell RNA - SuSa [nTPM]":"35.6","Cell RNA - T-47d [nTPM]":"47.9","Cell RNA - THP-1 [nTPM]":"31.3","Cell RNA - TIME [nTPM]":"43.6","Cell RNA - U-138 MG [nTPM]":"30.3","Cell RNA - U-2 OS [nTPM]":"43.1","Cell RNA - U-2197 [nTPM]":"55.8","Cell RNA - U-251 MG [nTPM]":"23.7","Cell RNA - U-266\/70 [nTPM]":"75.5","Cell RNA - U-266\/84 [nTPM]":"184.3","Cell RNA - U-698 [nTPM]":"22.0","Cell RNA - U-87 MG [nTPM]":"89.5","Cell RNA - U-937 [nTPM]":"61.3","Cell RNA - WM-115 [nTPM]":"24.6","Blood RNA - basophil [nTPM]":"285.2","Blood RNA - classical monocyte [nTPM]":"455.4","Blood RNA - eosinophil [nTPM]":"318.7","Blood RNA - gdT-cell [nTPM]":"47.6","Blood RNA - intermediate monocyte [nTPM]":"676.4","Blood RNA - MAIT T-cell [nTPM]":"43.1","Blood RNA - memory B-cell [nTPM]":"83.9","Blood RNA - memory CD4 T-cell [nTPM]":"35.5","Blood RNA - memory CD8 T-cell [nTPM]":"36.1","Blood RNA - myeloid DC [nTPM]":"175.1","Blood RNA - naive B-cell [nTPM]":"65.9","Blood RNA - naive CD4 T-cell [nTPM]":"40.8","Blood RNA - naive CD8 T-cell [nTPM]":"37.9","Blood RNA - neutrophil [nTPM]":"627.6","Blood RNA - NK-cell [nTPM]":"60.5","Blood RNA - non-classical monocyte [nTPM]":"731.4","Blood RNA - plasmacytoid DC [nTPM]":"33.0","Blood RNA - T-reg [nTPM]":"43.7","Blood RNA - total PBMC [nTPM]":"407.2","Brain RNA - amygdala [nTPM]":"50.1","Brain RNA - basal ganglia [nTPM]":"51.5","Brain RNA - cerebellum [nTPM]":"62.1","Brain RNA - cerebral cortex [nTPM]":"50.8","Brain RNA - hippocampal formation [nTPM]":"49.9","Brain RNA - hypothalamus [nTPM]":"66.2","Brain RNA - medulla oblongata [nTPM]":"66.0","Brain RNA - midbrain [nTPM]":"59.4","Brain RNA - pons [nTPM]":"69.0","Brain RNA - spinal cord [nTPM]":"66.3","Brain RNA - thalamus [nTPM]":"59.1","Brain RNA - white matter [nTPM]":"102.2","Single Cell Type RNA - Adipocytes [nTPM]":"98.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"317.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"405.0","Single Cell Type RNA - Astrocytes [nTPM]":"36.9","Single Cell Type RNA - B-cells [nTPM]":"92.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"58.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"83.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"103.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.3","Single Cell Type RNA - Bipolar cells [nTPM]":"97.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"105.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"87.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"777.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"100.1","Single Cell Type RNA - Club cells [nTPM]":"280.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"450.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"177.4","Single Cell Type RNA - dendritic cells [nTPM]":"67.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"83.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"150.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"85.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"51.5","Single Cell Type RNA - Endothelial cells [nTPM]":"79.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"98.1","Single Cell Type RNA - Erythroid cells [nTPM]":"106.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"104.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"65.2","Single Cell Type RNA - Fibroblasts [nTPM]":"122.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"133.8","Single Cell Type RNA - granulocytes [nTPM]":"257.0","Single Cell Type RNA - Granulosa cells [nTPM]":"49.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"134.6","Single Cell Type RNA - Hepatocytes [nTPM]":"50.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"921.2","Single Cell Type RNA - Horizontal cells [nTPM]":"77.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"99.3","Single Cell Type RNA - Ionocytes [nTPM]":"201.4","Single Cell Type RNA - Kupffer cells [nTPM]":"564.3","Single Cell Type RNA - Langerhans cells [nTPM]":"89.9","Single Cell Type RNA - Late spermatids [nTPM]":"6.0","Single Cell Type RNA - Leydig cells [nTPM]":"88.6","Single Cell Type RNA - Macrophages [nTPM]":"524.6","Single Cell Type RNA - Melanocytes [nTPM]":"318.4","Single Cell Type RNA - Microglial cells [nTPM]":"56.2","Single Cell Type RNA - monocytes [nTPM]":"259.2","Single Cell Type RNA - Muller glia cells [nTPM]":"532.6","Single Cell Type RNA - NK-cells [nTPM]":"53.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"49.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"64.7","Single Cell Type RNA - Paneth cells [nTPM]":"125.5","Single Cell Type RNA - Peritubular cells [nTPM]":"105.7","Single Cell Type RNA - Plasma cells [nTPM]":"87.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"87.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"77.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"304.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"147.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"88.0","Single Cell Type RNA - Sertoli cells [nTPM]":"177.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"74.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"157.0","Single Cell Type RNA - Spermatocytes [nTPM]":"14.0","Single Cell Type RNA - Spermatogonia [nTPM]":"63.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"84.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"64.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"148.2","Single Cell Type RNA - T-cells [nTPM]":"61.3","Single Cell Type RNA - Theca cells [nTPM]":"53.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"89.7","Single Cell Type RNA - Urothelial cells [nTPM]":"139.9"},{"Gene":"CLN3","Gene synonym":["BTN1","BTS","JNCL"],"Ensembl":"ENSG00000188603","Gene description":"CLN3 lysosomal\/endosomal transmembrane protein, battenin","Uniprot":["Q13286"],"Chromosome":"16","Position":"28474111-28495575","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"315.9","Extravillous trophoblasts":"106.9","Syncytiotrophoblasts":"451.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"178.0","SK-BR-3":"186.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063280"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063280":"AB_2684975"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.1","Tissue RNA - adrenal gland [nTPM]":"30.5","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"19.6","Tissue RNA - basal ganglia [nTPM]":"14.2","Tissue RNA - bone marrow [nTPM]":"13.4","Tissue RNA - breast [nTPM]":"21.4","Tissue RNA - cerebellum [nTPM]":"14.2","Tissue RNA - cerebral cortex [nTPM]":"16.0","Tissue RNA - cervix [nTPM]":"16.9","Tissue RNA - choroid plexus [nTPM]":"16.5","Tissue RNA - colon [nTPM]":"38.3","Tissue RNA - duodenum [nTPM]":"21.9","Tissue RNA - endometrium 1 [nTPM]":"15.9","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"22.2","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"15.2","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"13.2","Tissue RNA - hypothalamus [nTPM]":"13.6","Tissue RNA - kidney [nTPM]":"21.2","Tissue RNA - liver [nTPM]":"31.9","Tissue RNA - lung [nTPM]":"23.6","Tissue RNA - lymph node [nTPM]":"13.8","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"16.8","Tissue RNA - pancreas [nTPM]":"27.7","Tissue RNA - parathyroid gland [nTPM]":"30.0","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"36.9","Tissue RNA - pons [nTPM]":"15.1","Tissue RNA - prostate [nTPM]":"17.3","Tissue RNA - rectum [nTPM]":"29.2","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"34.5","Tissue RNA - seminal vesicle [nTPM]":"21.0","Tissue RNA - skeletal muscle [nTPM]":"14.5","Tissue RNA - skin 1 [nTPM]":"24.1","Tissue RNA - small intestine [nTPM]":"25.7","Tissue RNA - smooth muscle [nTPM]":"13.3","Tissue RNA - spinal cord [nTPM]":"13.5","Tissue RNA - spleen [nTPM]":"20.4","Tissue RNA - stomach 1 [nTPM]":"26.1","Tissue RNA - testis [nTPM]":"7.9","Tissue RNA - thalamus [nTPM]":"15.6","Tissue RNA - thymus [nTPM]":"14.0","Tissue RNA - thyroid gland [nTPM]":"24.7","Tissue RNA - tongue [nTPM]":"13.8","Tissue RNA - tonsil [nTPM]":"12.1","Tissue RNA - urinary bladder [nTPM]":"19.3","Tissue RNA - vagina [nTPM]":"15.6","Tissue RNA - white matter [nTPM]":"17.1","Cell RNA - A-431 [nTPM]":"23.1","Cell RNA - A549 [nTPM]":"39.2","Cell RNA - AF22 [nTPM]":"15.4","Cell RNA - AN3-CA [nTPM]":"38.4","Cell RNA - ASC diff [nTPM]":"41.1","Cell RNA - ASC TERT1 [nTPM]":"19.9","Cell RNA - BEWO [nTPM]":"178.0","Cell RNA - BJ [nTPM]":"14.8","Cell RNA - BJ hTERT+ [nTPM]":"40.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.9","Cell RNA - CACO-2 [nTPM]":"19.7","Cell RNA - CAPAN-2 [nTPM]":"52.9","Cell RNA - Daudi [nTPM]":"16.0","Cell RNA - EFO-21 [nTPM]":"45.8","Cell RNA - fHDF\/TERT166 [nTPM]":"24.8","Cell RNA - GAMG [nTPM]":"52.0","Cell RNA - HaCaT [nTPM]":"23.5","Cell RNA - HAP1 [nTPM]":"25.8","Cell RNA - HBEC3-KT [nTPM]":"24.7","Cell RNA - HBF TERT88 [nTPM]":"12.9","Cell RNA - HDLM-2 [nTPM]":"38.0","Cell RNA - HEK 293 [nTPM]":"38.5","Cell RNA - HEL [nTPM]":"15.6","Cell RNA - HeLa [nTPM]":"24.1","Cell RNA - Hep G2 [nTPM]":"60.6","Cell RNA - HHSteC [nTPM]":"60.5","Cell RNA - HL-60 [nTPM]":"23.3","Cell RNA - HMC-1 [nTPM]":"64.7","Cell RNA - HSkMC [nTPM]":"28.0","Cell RNA - hTCEpi [nTPM]":"66.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.9","Cell RNA - hTERT-HME1 [nTPM]":"14.7","Cell RNA - hTERT-RPE1 [nTPM]":"26.3","Cell RNA - HUVEC TERT2 [nTPM]":"32.9","Cell RNA - JURKAT [nTPM]":"24.9","Cell RNA - K-562 [nTPM]":"30.9","Cell RNA - Karpas-707 [nTPM]":"55.0","Cell RNA - LHCN-M2 [nTPM]":"28.8","Cell RNA - MCF7 [nTPM]":"61.9","Cell RNA - MOLT-4 [nTPM]":"20.7","Cell RNA - NB-4 [nTPM]":"45.1","Cell RNA - NTERA-2 [nTPM]":"21.8","Cell RNA - OE19 [nTPM]":"35.3","Cell RNA - PC-3 [nTPM]":"26.0","Cell RNA - REH [nTPM]":"37.2","Cell RNA - RH-30 [nTPM]":"13.4","Cell RNA - RPMI-8226 [nTPM]":"54.5","Cell RNA - RPTEC TERT1 [nTPM]":"30.2","Cell RNA - RT4 [nTPM]":"53.0","Cell RNA - SCLC-21H [nTPM]":"20.8","Cell RNA - SH-SY5Y [nTPM]":"19.6","Cell RNA - SiHa [nTPM]":"5.7","Cell RNA - SK-BR-3 [nTPM]":"186.5","Cell RNA - SK-MEL-30 [nTPM]":"18.3","Cell RNA - SuSa [nTPM]":"14.0","Cell RNA - T-47d [nTPM]":"62.2","Cell RNA - THP-1 [nTPM]":"32.4","Cell RNA - TIME [nTPM]":"20.2","Cell RNA - U-138 MG [nTPM]":"19.2","Cell RNA - U-2 OS [nTPM]":"10.1","Cell RNA - U-2197 [nTPM]":"24.9","Cell RNA - U-251 MG [nTPM]":"22.5","Cell RNA - U-266\/70 [nTPM]":"58.3","Cell RNA - U-266\/84 [nTPM]":"64.2","Cell RNA - U-698 [nTPM]":"15.9","Cell RNA - U-87 MG [nTPM]":"28.4","Cell RNA - U-937 [nTPM]":"47.3","Cell RNA - WM-115 [nTPM]":"11.9","Blood RNA - basophil [nTPM]":"63.4","Blood RNA - classical monocyte [nTPM]":"59.8","Blood RNA - eosinophil [nTPM]":"98.4","Blood RNA - gdT-cell [nTPM]":"57.6","Blood RNA - intermediate monocyte [nTPM]":"47.6","Blood RNA - MAIT T-cell [nTPM]":"42.7","Blood RNA - memory B-cell [nTPM]":"24.3","Blood RNA - memory CD4 T-cell [nTPM]":"43.6","Blood RNA - memory CD8 T-cell [nTPM]":"53.6","Blood RNA - myeloid DC [nTPM]":"63.8","Blood RNA - naive B-cell [nTPM]":"29.3","Blood RNA - naive CD4 T-cell [nTPM]":"38.3","Blood RNA - naive CD8 T-cell [nTPM]":"40.6","Blood RNA - neutrophil [nTPM]":"23.8","Blood RNA - NK-cell [nTPM]":"41.2","Blood RNA - non-classical monocyte [nTPM]":"38.7","Blood RNA - plasmacytoid DC [nTPM]":"68.1","Blood RNA - T-reg [nTPM]":"53.5","Blood RNA - total PBMC [nTPM]":"46.6","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"14.2","Brain RNA - cerebellum [nTPM]":"14.2","Brain RNA - cerebral cortex [nTPM]":"16.0","Brain RNA - hippocampal formation [nTPM]":"13.2","Brain RNA - hypothalamus [nTPM]":"13.6","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"15.1","Brain RNA - spinal cord [nTPM]":"13.5","Brain RNA - thalamus [nTPM]":"15.6","Brain RNA - white matter [nTPM]":"17.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.9","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"10.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"10.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"315.9","Single Cell Type RNA - dendritic cells [nTPM]":"25.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"46.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"11.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.0","Single Cell Type RNA - Erythroid cells [nTPM]":"17.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"106.9","Single Cell Type RNA - Fibroblasts [nTPM]":"9.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.6","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"7.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"39.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"70.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"36.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"17.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"17.5","Single Cell Type RNA - Muller glia cells [nTPM]":"25.0","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"43.7","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"53.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"8.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"451.4","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"3.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"50.2","Single Cell Type RNA - Urothelial cells [nTPM]":"13.3"},{"Gene":"CLN5","Gene synonym":[],"Ensembl":"ENSG00000102805","Gene description":"CLN5 intracellular trafficking protein","Uniprot":["O75503"],"Chromosome":"13","Position":"76990660-77019143","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"128.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041788"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"470000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041788":"AB_10962726"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.52e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.9","Tissue RNA - adrenal gland [nTPM]":"19.8","Tissue RNA - amygdala [nTPM]":"13.9","Tissue RNA - appendix [nTPM]":"14.4","Tissue RNA - basal ganglia [nTPM]":"12.8","Tissue RNA - bone marrow [nTPM]":"13.3","Tissue RNA - breast [nTPM]":"21.8","Tissue RNA - cerebellum [nTPM]":"27.0","Tissue RNA - cerebral cortex [nTPM]":"18.9","Tissue RNA - cervix [nTPM]":"25.1","Tissue RNA - choroid plexus [nTPM]":"17.0","Tissue RNA - colon [nTPM]":"16.1","Tissue RNA - duodenum [nTPM]":"11.3","Tissue RNA - endometrium 1 [nTPM]":"19.1","Tissue RNA - epididymis [nTPM]":"41.9","Tissue RNA - esophagus [nTPM]":"10.9","Tissue RNA - fallopian tube [nTPM]":"24.5","Tissue RNA - gallbladder [nTPM]":"25.2","Tissue RNA - heart muscle [nTPM]":"14.2","Tissue RNA - hippocampal formation [nTPM]":"13.5","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"50.5","Tissue RNA - liver [nTPM]":"35.5","Tissue RNA - lung [nTPM]":"20.5","Tissue RNA - lymph node [nTPM]":"19.8","Tissue RNA - medulla oblongata [nTPM]":"12.5","Tissue RNA - midbrain [nTPM]":"11.6","Tissue RNA - ovary [nTPM]":"26.6","Tissue RNA - pancreas [nTPM]":"16.8","Tissue RNA - parathyroid gland [nTPM]":"45.6","Tissue RNA - pituitary gland [nTPM]":"14.4","Tissue RNA - placenta [nTPM]":"23.3","Tissue RNA - pons [nTPM]":"12.2","Tissue RNA - prostate [nTPM]":"22.3","Tissue RNA - rectum [nTPM]":"16.5","Tissue RNA - retina [nTPM]":"24.1","Tissue RNA - salivary gland [nTPM]":"21.4","Tissue RNA - seminal vesicle [nTPM]":"22.7","Tissue RNA - skeletal muscle [nTPM]":"8.4","Tissue RNA - skin 1 [nTPM]":"14.6","Tissue RNA - small intestine [nTPM]":"13.6","Tissue RNA - smooth muscle [nTPM]":"15.9","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"16.7","Tissue RNA - stomach 1 [nTPM]":"18.8","Tissue RNA - testis [nTPM]":"16.1","Tissue RNA - thalamus [nTPM]":"13.0","Tissue RNA - thymus [nTPM]":"18.3","Tissue RNA - thyroid gland [nTPM]":"72.9","Tissue RNA - tongue [nTPM]":"10.7","Tissue RNA - tonsil [nTPM]":"18.5","Tissue RNA - urinary bladder [nTPM]":"18.8","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"19.0","Cell RNA - A-431 [nTPM]":"25.0","Cell RNA - A549 [nTPM]":"11.7","Cell RNA - AF22 [nTPM]":"16.4","Cell RNA - AN3-CA [nTPM]":"13.7","Cell RNA - ASC diff [nTPM]":"74.4","Cell RNA - ASC TERT1 [nTPM]":"48.5","Cell RNA - BEWO [nTPM]":"21.1","Cell RNA - BJ [nTPM]":"23.7","Cell RNA - BJ hTERT+ [nTPM]":"43.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.9","Cell RNA - CACO-2 [nTPM]":"12.3","Cell RNA - CAPAN-2 [nTPM]":"23.2","Cell RNA - Daudi [nTPM]":"9.7","Cell RNA - EFO-21 [nTPM]":"17.3","Cell RNA - fHDF\/TERT166 [nTPM]":"33.5","Cell RNA - GAMG [nTPM]":"21.0","Cell RNA - HaCaT [nTPM]":"25.0","Cell RNA - HAP1 [nTPM]":"11.5","Cell RNA - HBEC3-KT [nTPM]":"25.5","Cell RNA - HBF TERT88 [nTPM]":"20.0","Cell RNA - HDLM-2 [nTPM]":"18.4","Cell RNA - HEK 293 [nTPM]":"21.5","Cell RNA - HEL [nTPM]":"13.9","Cell RNA - HeLa [nTPM]":"13.1","Cell RNA - Hep G2 [nTPM]":"12.2","Cell RNA - HHSteC [nTPM]":"33.8","Cell RNA - HL-60 [nTPM]":"19.5","Cell RNA - HMC-1 [nTPM]":"20.4","Cell RNA - HSkMC [nTPM]":"43.6","Cell RNA - hTCEpi [nTPM]":"28.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.9","Cell RNA - hTERT-HME1 [nTPM]":"18.7","Cell RNA - hTERT-RPE1 [nTPM]":"37.1","Cell RNA - HUVEC TERT2 [nTPM]":"33.0","Cell RNA - JURKAT [nTPM]":"13.5","Cell RNA - K-562 [nTPM]":"9.4","Cell RNA - Karpas-707 [nTPM]":"17.2","Cell RNA - LHCN-M2 [nTPM]":"43.2","Cell RNA - MCF7 [nTPM]":"7.7","Cell RNA - MOLT-4 [nTPM]":"11.6","Cell RNA - NB-4 [nTPM]":"12.5","Cell RNA - NTERA-2 [nTPM]":"10.7","Cell RNA - OE19 [nTPM]":"48.6","Cell RNA - PC-3 [nTPM]":"10.4","Cell RNA - REH [nTPM]":"9.5","Cell RNA - RH-30 [nTPM]":"14.4","Cell RNA - RPMI-8226 [nTPM]":"9.0","Cell RNA - RPTEC TERT1 [nTPM]":"42.6","Cell RNA - RT4 [nTPM]":"13.8","Cell RNA - SCLC-21H [nTPM]":"7.3","Cell RNA - SH-SY5Y [nTPM]":"11.3","Cell RNA - SiHa [nTPM]":"14.1","Cell RNA - SK-BR-3 [nTPM]":"17.4","Cell RNA - SK-MEL-30 [nTPM]":"26.3","Cell RNA - SuSa [nTPM]":"21.3","Cell RNA - T-47d [nTPM]":"19.0","Cell RNA - THP-1 [nTPM]":"26.0","Cell RNA - TIME [nTPM]":"31.2","Cell RNA - U-138 MG [nTPM]":"13.2","Cell RNA - U-2 OS [nTPM]":"10.4","Cell RNA - U-2197 [nTPM]":"15.4","Cell RNA - U-251 MG [nTPM]":"14.2","Cell RNA - U-266\/70 [nTPM]":"21.7","Cell RNA - U-266\/84 [nTPM]":"30.0","Cell RNA - U-698 [nTPM]":"12.2","Cell RNA - U-87 MG [nTPM]":"35.4","Cell RNA - U-937 [nTPM]":"13.5","Cell RNA - WM-115 [nTPM]":"29.2","Blood RNA - basophil [nTPM]":"58.4","Blood RNA - classical monocyte [nTPM]":"15.6","Blood RNA - eosinophil [nTPM]":"39.4","Blood RNA - gdT-cell [nTPM]":"3.5","Blood RNA - intermediate monocyte [nTPM]":"22.4","Blood RNA - MAIT T-cell [nTPM]":"3.1","Blood RNA - memory B-cell [nTPM]":"13.2","Blood RNA - memory CD4 T-cell [nTPM]":"17.0","Blood RNA - memory CD8 T-cell [nTPM]":"6.0","Blood RNA - myeloid DC [nTPM]":"10.8","Blood RNA - naive B-cell [nTPM]":"14.5","Blood RNA - naive CD4 T-cell [nTPM]":"21.5","Blood RNA - naive CD8 T-cell [nTPM]":"13.3","Blood RNA - neutrophil [nTPM]":"11.4","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"27.7","Blood RNA - plasmacytoid DC [nTPM]":"11.0","Blood RNA - T-reg [nTPM]":"25.6","Blood RNA - total PBMC [nTPM]":"14.1","Brain RNA - amygdala [nTPM]":"13.9","Brain RNA - basal ganglia [nTPM]":"12.8","Brain RNA - cerebellum [nTPM]":"27.0","Brain RNA - cerebral cortex [nTPM]":"18.9","Brain RNA - hippocampal formation [nTPM]":"13.5","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"12.5","Brain RNA - midbrain [nTPM]":"11.6","Brain RNA - pons [nTPM]":"12.2","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"13.0","Brain RNA - white matter [nTPM]":"19.0","Single Cell Type RNA - Adipocytes [nTPM]":"30.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.4","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"29.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"75.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"19.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"59.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"68.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.2","Single Cell Type RNA - dendritic cells [nTPM]":"15.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"39.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.0","Single Cell Type RNA - Endothelial cells [nTPM]":"24.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.8","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"128.5","Single Cell Type RNA - Fibroblasts [nTPM]":"36.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.8","Single Cell Type RNA - granulocytes [nTPM]":"22.2","Single Cell Type RNA - Granulosa cells [nTPM]":"23.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.7","Single Cell Type RNA - Hepatocytes [nTPM]":"33.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"48.1","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.6","Single Cell Type RNA - Ionocytes [nTPM]":"97.6","Single Cell Type RNA - Kupffer cells [nTPM]":"22.4","Single Cell Type RNA - Langerhans cells [nTPM]":"16.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.5","Single Cell Type RNA - Leydig cells [nTPM]":"49.7","Single Cell Type RNA - Macrophages [nTPM]":"22.7","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"31.5","Single Cell Type RNA - Muller glia cells [nTPM]":"50.4","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.0","Single Cell Type RNA - Paneth cells [nTPM]":"14.4","Single Cell Type RNA - Peritubular cells [nTPM]":"47.4","Single Cell Type RNA - Plasma cells [nTPM]":"18.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"44.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"48.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.2","Single Cell Type RNA - Spermatocytes [nTPM]":"25.8","Single Cell Type RNA - Spermatogonia [nTPM]":"34.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.4","Single Cell Type RNA - T-cells [nTPM]":"15.2","Single Cell Type RNA - Theca cells [nTPM]":"34.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.4","Single Cell Type RNA - Urothelial cells [nTPM]":"21.8"},{"Gene":"CLN6","Gene synonym":["FLJ20561","HsT18960","nclf"],"Ensembl":"ENSG00000128973","Gene description":"CLN6 transmembrane ER protein","Uniprot":["Q9NWW5"],"Chromosome":"15","Position":"68206992-68257211","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"181.8","Hofbauer cells":"88.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066046","HPA066759"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoli","Vesicles"],"Antibody RRID":{"HPA066046":"AB_2685604","HPA066759":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"17.6","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"14.8","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"29.9","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"13.3","Tissue RNA - cerebral cortex [nTPM]":"14.9","Tissue RNA - cervix [nTPM]":"11.0","Tissue RNA - choroid plexus [nTPM]":"13.2","Tissue RNA - colon [nTPM]":"17.5","Tissue RNA - duodenum [nTPM]":"14.6","Tissue RNA - endometrium 1 [nTPM]":"9.8","Tissue RNA - epididymis [nTPM]":"6.8","Tissue RNA - esophagus [nTPM]":"16.9","Tissue RNA - fallopian tube [nTPM]":"9.8","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"9.3","Tissue RNA - hippocampal formation [nTPM]":"12.1","Tissue RNA - hypothalamus [nTPM]":"12.6","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"22.7","Tissue RNA - lung [nTPM]":"13.2","Tissue RNA - lymph node [nTPM]":"16.2","Tissue RNA - medulla oblongata [nTPM]":"13.3","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"6.8","Tissue RNA - pancreas [nTPM]":"19.1","Tissue RNA - parathyroid gland [nTPM]":"10.4","Tissue RNA - pituitary gland [nTPM]":"10.1","Tissue RNA - placenta [nTPM]":"11.6","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"12.4","Tissue RNA - rectum [nTPM]":"14.9","Tissue RNA - retina [nTPM]":"11.8","Tissue RNA - salivary gland [nTPM]":"14.8","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"17.0","Tissue RNA - skin 1 [nTPM]":"14.7","Tissue RNA - small intestine [nTPM]":"14.6","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"12.8","Tissue RNA - spleen [nTPM]":"20.7","Tissue RNA - stomach 1 [nTPM]":"13.3","Tissue RNA - testis [nTPM]":"10.9","Tissue RNA - thalamus [nTPM]":"13.0","Tissue RNA - thymus [nTPM]":"11.6","Tissue RNA - thyroid gland [nTPM]":"12.9","Tissue RNA - tongue [nTPM]":"7.3","Tissue RNA - tonsil [nTPM]":"16.7","Tissue RNA - urinary bladder [nTPM]":"10.7","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"14.5","Cell RNA - A-431 [nTPM]":"38.2","Cell RNA - A549 [nTPM]":"93.1","Cell RNA - AF22 [nTPM]":"23.9","Cell RNA - AN3-CA [nTPM]":"33.9","Cell RNA - ASC diff [nTPM]":"14.5","Cell RNA - ASC TERT1 [nTPM]":"11.8","Cell RNA - BEWO [nTPM]":"57.1","Cell RNA - BJ [nTPM]":"35.3","Cell RNA - BJ hTERT+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.9","Cell RNA - CACO-2 [nTPM]":"72.1","Cell RNA - CAPAN-2 [nTPM]":"60.5","Cell RNA - Daudi [nTPM]":"57.6","Cell RNA - EFO-21 [nTPM]":"17.2","Cell RNA - fHDF\/TERT166 [nTPM]":"21.4","Cell RNA - GAMG [nTPM]":"31.7","Cell RNA - HaCaT [nTPM]":"69.5","Cell RNA - HAP1 [nTPM]":"69.8","Cell RNA - HBEC3-KT [nTPM]":"34.5","Cell RNA - HBF TERT88 [nTPM]":"17.0","Cell RNA - HDLM-2 [nTPM]":"38.5","Cell RNA - HEK 293 [nTPM]":"82.3","Cell RNA - HEL [nTPM]":"84.3","Cell RNA - HeLa [nTPM]":"66.1","Cell RNA - Hep G2 [nTPM]":"54.3","Cell RNA - HHSteC [nTPM]":"29.7","Cell RNA - HL-60 [nTPM]":"95.6","Cell RNA - HMC-1 [nTPM]":"58.1","Cell RNA - HSkMC [nTPM]":"20.8","Cell RNA - hTCEpi [nTPM]":"11.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.7","Cell RNA - hTERT-HME1 [nTPM]":"23.7","Cell RNA - hTERT-RPE1 [nTPM]":"9.0","Cell RNA - HUVEC TERT2 [nTPM]":"29.1","Cell RNA - JURKAT [nTPM]":"33.1","Cell RNA - K-562 [nTPM]":"56.9","Cell RNA - Karpas-707 [nTPM]":"116.0","Cell RNA - LHCN-M2 [nTPM]":"33.6","Cell RNA - MCF7 [nTPM]":"103.8","Cell RNA - MOLT-4 [nTPM]":"44.0","Cell RNA - NB-4 [nTPM]":"69.4","Cell RNA - NTERA-2 [nTPM]":"57.1","Cell RNA - OE19 [nTPM]":"67.3","Cell RNA - PC-3 [nTPM]":"38.3","Cell RNA - REH [nTPM]":"42.1","Cell RNA - RH-30 [nTPM]":"71.8","Cell RNA - RPMI-8226 [nTPM]":"80.6","Cell RNA - RPTEC TERT1 [nTPM]":"36.2","Cell RNA - RT4 [nTPM]":"97.0","Cell RNA - SCLC-21H [nTPM]":"48.2","Cell RNA - SH-SY5Y [nTPM]":"20.0","Cell RNA - SiHa [nTPM]":"39.5","Cell RNA - SK-BR-3 [nTPM]":"61.7","Cell RNA - SK-MEL-30 [nTPM]":"34.3","Cell RNA - SuSa [nTPM]":"18.0","Cell RNA - T-47d [nTPM]":"33.1","Cell RNA - THP-1 [nTPM]":"95.5","Cell RNA - TIME [nTPM]":"19.3","Cell RNA - U-138 MG [nTPM]":"48.1","Cell RNA - U-2 OS [nTPM]":"55.7","Cell RNA - U-2197 [nTPM]":"35.8","Cell RNA - U-251 MG [nTPM]":"127.2","Cell RNA - U-266\/70 [nTPM]":"81.3","Cell RNA - U-266\/84 [nTPM]":"97.3","Cell RNA - U-698 [nTPM]":"47.4","Cell RNA - U-87 MG [nTPM]":"30.0","Cell RNA - U-937 [nTPM]":"115.4","Cell RNA - WM-115 [nTPM]":"47.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"8.8","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"13.0","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"2.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.2","Blood RNA - memory CD8 T-cell [nTPM]":"4.3","Blood RNA - myeloid DC [nTPM]":"5.2","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"10.5","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"16.1","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"13.3","Brain RNA - cerebral cortex [nTPM]":"14.9","Brain RNA - hippocampal formation [nTPM]":"12.1","Brain RNA - hypothalamus [nTPM]":"12.6","Brain RNA - medulla oblongata [nTPM]":"13.3","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"12.8","Brain RNA - thalamus [nTPM]":"13.0","Brain RNA - white matter [nTPM]":"14.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"13.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"181.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.8","Single Cell Type RNA - dendritic cells [nTPM]":"7.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.8","Single Cell Type RNA - Endothelial cells [nTPM]":"9.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.1","Single Cell Type RNA - Erythroid cells [nTPM]":"32.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.4","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"5.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"21.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"88.4","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.5","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"24.2","Single Cell Type RNA - Langerhans cells [nTPM]":"14.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"11.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"12.9","Single Cell Type RNA - Muller glia cells [nTPM]":"16.9","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.6","Single Cell Type RNA - Paneth cells [nTPM]":"26.0","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"33.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"19.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.8","Single Cell Type RNA - T-cells [nTPM]":"9.5","Single Cell Type RNA - Theca cells [nTPM]":"5.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.6","Single Cell Type RNA - Urothelial cells [nTPM]":"16.3"},{"Gene":"CLN8","Gene synonym":["C8orf61","EPMR","FLJ39417","TLCD6"],"Ensembl":"ENSG00000182372","Gene description":"CLN8 transmembrane ER and ERGIC protein","Uniprot":["Q9UBY8"],"Chromosome":"8","Position":"1755778-1801711","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"136.8","Syncytiotrophoblasts":"131.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"76.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"76.7"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.36e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.4","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"11.4","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"15.7","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"4.3","Tissue RNA - cerebellum [nTPM]":"14.6","Tissue RNA - cerebral cortex [nTPM]":"12.4","Tissue RNA - cervix [nTPM]":"4.7","Tissue RNA - choroid plexus [nTPM]":"6.6","Tissue RNA - colon [nTPM]":"4.9","Tissue RNA - duodenum [nTPM]":"5.0","Tissue RNA - endometrium 1 [nTPM]":"3.2","Tissue RNA - epididymis [nTPM]":"11.2","Tissue RNA - esophagus [nTPM]":"9.8","Tissue RNA - fallopian tube [nTPM]":"3.3","Tissue RNA - gallbladder [nTPM]":"7.5","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"10.6","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"8.9","Tissue RNA - lung [nTPM]":"8.9","Tissue RNA - lymph node [nTPM]":"6.5","Tissue RNA - medulla oblongata [nTPM]":"18.2","Tissue RNA - midbrain [nTPM]":"15.2","Tissue RNA - ovary [nTPM]":"2.5","Tissue RNA - pancreas [nTPM]":"10.1","Tissue RNA - parathyroid gland [nTPM]":"8.0","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"6.0","Tissue RNA - pons [nTPM]":"18.5","Tissue RNA - prostate [nTPM]":"3.8","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"3.8","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"3.6","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"13.2","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"16.9","Tissue RNA - spleen [nTPM]":"7.9","Tissue RNA - stomach 1 [nTPM]":"6.8","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"15.1","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"3.3","Tissue RNA - tonsil [nTPM]":"7.2","Tissue RNA - urinary bladder [nTPM]":"4.4","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"24.3","Cell RNA - A-431 [nTPM]":"3.6","Cell RNA - A549 [nTPM]":"8.5","Cell RNA - AF22 [nTPM]":"6.2","Cell RNA - AN3-CA [nTPM]":"6.5","Cell RNA - ASC diff [nTPM]":"8.3","Cell RNA - ASC TERT1 [nTPM]":"8.4","Cell RNA - BEWO [nTPM]":"14.8","Cell RNA - BJ [nTPM]":"8.3","Cell RNA - BJ hTERT+ [nTPM]":"5.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.2","Cell RNA - CACO-2 [nTPM]":"8.6","Cell RNA - CAPAN-2 [nTPM]":"10.0","Cell RNA - Daudi [nTPM]":"4.4","Cell RNA - EFO-21 [nTPM]":"2.3","Cell RNA - fHDF\/TERT166 [nTPM]":"8.2","Cell RNA - GAMG [nTPM]":"5.6","Cell RNA - HaCaT [nTPM]":"13.7","Cell RNA - HAP1 [nTPM]":"4.9","Cell RNA - HBEC3-KT [nTPM]":"15.6","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"3.6","Cell RNA - HEL [nTPM]":"4.4","Cell RNA - HeLa [nTPM]":"3.2","Cell RNA - Hep G2 [nTPM]":"4.9","Cell RNA - HHSteC [nTPM]":"4.7","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"19.1","Cell RNA - HSkMC [nTPM]":"8.4","Cell RNA - hTCEpi [nTPM]":"12.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.8","Cell RNA - hTERT-HME1 [nTPM]":"4.1","Cell RNA - hTERT-RPE1 [nTPM]":"10.1","Cell RNA - HUVEC TERT2 [nTPM]":"9.2","Cell RNA - JURKAT [nTPM]":"3.2","Cell RNA - K-562 [nTPM]":"6.0","Cell RNA - Karpas-707 [nTPM]":"2.6","Cell RNA - LHCN-M2 [nTPM]":"13.1","Cell RNA - MCF7 [nTPM]":"9.0","Cell RNA - MOLT-4 [nTPM]":"6.0","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"6.1","Cell RNA - OE19 [nTPM]":"14.0","Cell RNA - PC-3 [nTPM]":"7.3","Cell RNA - REH [nTPM]":"4.2","Cell RNA - RH-30 [nTPM]":"4.3","Cell RNA - RPMI-8226 [nTPM]":"3.4","Cell RNA - RPTEC TERT1 [nTPM]":"7.8","Cell RNA - RT4 [nTPM]":"15.4","Cell RNA - SCLC-21H [nTPM]":"3.2","Cell RNA - SH-SY5Y [nTPM]":"3.9","Cell RNA - SiHa [nTPM]":"3.5","Cell RNA - SK-BR-3 [nTPM]":"8.1","Cell RNA - SK-MEL-30 [nTPM]":"4.6","Cell RNA - SuSa [nTPM]":"12.7","Cell RNA - T-47d [nTPM]":"16.2","Cell RNA - THP-1 [nTPM]":"4.2","Cell RNA - TIME [nTPM]":"17.3","Cell RNA - U-138 MG [nTPM]":"11.3","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"5.2","Cell RNA - U-266\/70 [nTPM]":"1.5","Cell RNA - U-266\/84 [nTPM]":"5.4","Cell RNA - U-698 [nTPM]":"5.0","Cell RNA - U-87 MG [nTPM]":"11.4","Cell RNA - U-937 [nTPM]":"7.3","Cell RNA - WM-115 [nTPM]":"16.9","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"10.6","Blood RNA - eosinophil [nTPM]":"4.7","Blood RNA - gdT-cell [nTPM]":"6.4","Blood RNA - intermediate monocyte [nTPM]":"13.6","Blood RNA - MAIT T-cell [nTPM]":"7.1","Blood RNA - memory B-cell [nTPM]":"10.3","Blood RNA - memory CD4 T-cell [nTPM]":"6.9","Blood RNA - memory CD8 T-cell [nTPM]":"4.5","Blood RNA - myeloid DC [nTPM]":"10.6","Blood RNA - naive B-cell [nTPM]":"14.0","Blood RNA - naive CD4 T-cell [nTPM]":"6.7","Blood RNA - naive CD8 T-cell [nTPM]":"4.4","Blood RNA - neutrophil [nTPM]":"3.7","Blood RNA - NK-cell [nTPM]":"5.1","Blood RNA - non-classical monocyte [nTPM]":"12.5","Blood RNA - plasmacytoid DC [nTPM]":"76.7","Blood RNA - T-reg [nTPM]":"8.0","Blood RNA - total PBMC [nTPM]":"6.4","Brain RNA - amygdala [nTPM]":"11.4","Brain RNA - basal ganglia [nTPM]":"15.7","Brain RNA - cerebellum [nTPM]":"14.6","Brain RNA - cerebral cortex [nTPM]":"12.4","Brain RNA - hippocampal formation [nTPM]":"10.6","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"18.2","Brain RNA - midbrain [nTPM]":"15.2","Brain RNA - pons [nTPM]":"18.5","Brain RNA - spinal cord [nTPM]":"16.9","Brain RNA - thalamus [nTPM]":"15.1","Brain RNA - white matter [nTPM]":"24.3","Single Cell Type RNA - Adipocytes [nTPM]":"18.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"30.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"54.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"71.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Bipolar cells [nTPM]":"27.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"37.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.0","Single Cell Type RNA - dendritic cells [nTPM]":"115.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"27.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.9","Single Cell Type RNA - Endothelial cells [nTPM]":"34.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.7","Single Cell Type RNA - Erythroid cells [nTPM]":"40.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.0","Single Cell Type RNA - Fibroblasts [nTPM]":"32.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.2","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"17.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.8","Single Cell Type RNA - Hepatocytes [nTPM]":"28.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.1","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.5","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"54.6","Single Cell Type RNA - Langerhans cells [nTPM]":"136.8","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"69.8","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"22.3","Single Cell Type RNA - Muller glia cells [nTPM]":"13.9","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.3","Single Cell Type RNA - Paneth cells [nTPM]":"20.7","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"76.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.8","Single Cell Type RNA - Spermatocytes [nTPM]":"34.4","Single Cell Type RNA - Spermatogonia [nTPM]":"23.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"63.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"131.6","Single Cell Type RNA - T-cells [nTPM]":"22.0","Single Cell Type RNA - Theca cells [nTPM]":"16.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.4","Single Cell Type RNA - Urothelial cells [nTPM]":"61.2"},{"Gene":"CTNS","Gene synonym":["CTNS-LSB","PQLC4","SLC66A4"],"Ensembl":"ENSG00000040531","Gene description":"Cystinosin, lysosomal cystine transporter","Uniprot":["O60931"],"Chromosome":"17","Position":"3636459-3663103","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Melanin biosynthesis","Protein transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"35.5","Late spermatids":"29.3","Theca cells":"30.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"34.3","granulocytes":"27.9","monocytes":"10.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"144.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046947"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles","Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA046947":"AB_2679872"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.33e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.39e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.3","Tissue RNA - adrenal gland [nTPM]":"19.5","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"10.0","Tissue RNA - basal ganglia [nTPM]":"17.0","Tissue RNA - bone marrow [nTPM]":"10.2","Tissue RNA - breast [nTPM]":"9.6","Tissue RNA - cerebellum [nTPM]":"13.5","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"20.3","Tissue RNA - choroid plexus [nTPM]":"12.1","Tissue RNA - colon [nTPM]":"8.3","Tissue RNA - duodenum [nTPM]":"12.2","Tissue RNA - endometrium 1 [nTPM]":"11.3","Tissue RNA - epididymis [nTPM]":"6.4","Tissue RNA - esophagus [nTPM]":"8.7","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"13.1","Tissue RNA - heart muscle [nTPM]":"10.5","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"10.3","Tissue RNA - kidney [nTPM]":"15.2","Tissue RNA - liver [nTPM]":"15.9","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"10.0","Tissue RNA - medulla oblongata [nTPM]":"16.5","Tissue RNA - midbrain [nTPM]":"16.8","Tissue RNA - ovary [nTPM]":"12.1","Tissue RNA - pancreas [nTPM]":"27.0","Tissue RNA - parathyroid gland [nTPM]":"13.6","Tissue RNA - pituitary gland [nTPM]":"9.6","Tissue RNA - placenta [nTPM]":"12.9","Tissue RNA - pons [nTPM]":"18.0","Tissue RNA - prostate [nTPM]":"10.8","Tissue RNA - rectum [nTPM]":"7.2","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"12.0","Tissue RNA - seminal vesicle [nTPM]":"11.6","Tissue RNA - skeletal muscle [nTPM]":"15.3","Tissue RNA - skin 1 [nTPM]":"19.2","Tissue RNA - small intestine [nTPM]":"11.0","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"10.9","Tissue RNA - spleen [nTPM]":"12.1","Tissue RNA - stomach 1 [nTPM]":"15.0","Tissue RNA - testis [nTPM]":"24.8","Tissue RNA - thalamus [nTPM]":"13.2","Tissue RNA - thymus [nTPM]":"8.8","Tissue RNA - thyroid gland [nTPM]":"9.2","Tissue RNA - tongue [nTPM]":"7.4","Tissue RNA - tonsil [nTPM]":"9.5","Tissue RNA - urinary bladder [nTPM]":"9.1","Tissue RNA - vagina [nTPM]":"9.4","Tissue RNA - white matter [nTPM]":"28.0","Cell RNA - A-431 [nTPM]":"17.6","Cell RNA - A549 [nTPM]":"37.0","Cell RNA - AF22 [nTPM]":"22.6","Cell RNA - AN3-CA [nTPM]":"18.2","Cell RNA - ASC diff [nTPM]":"34.5","Cell RNA - ASC TERT1 [nTPM]":"16.9","Cell RNA - BEWO [nTPM]":"13.0","Cell RNA - BJ [nTPM]":"19.6","Cell RNA - BJ hTERT+ [nTPM]":"28.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.0","Cell RNA - CACO-2 [nTPM]":"21.0","Cell RNA - CAPAN-2 [nTPM]":"16.0","Cell RNA - Daudi [nTPM]":"10.2","Cell RNA - EFO-21 [nTPM]":"17.8","Cell RNA - fHDF\/TERT166 [nTPM]":"11.6","Cell RNA - GAMG [nTPM]":"55.9","Cell RNA - HaCaT [nTPM]":"40.1","Cell RNA - HAP1 [nTPM]":"19.8","Cell RNA - HBEC3-KT [nTPM]":"12.1","Cell RNA - HBF TERT88 [nTPM]":"12.6","Cell RNA - HDLM-2 [nTPM]":"144.3","Cell RNA - HEK 293 [nTPM]":"33.7","Cell RNA - HEL [nTPM]":"10.8","Cell RNA - HeLa [nTPM]":"32.2","Cell RNA - Hep G2 [nTPM]":"19.3","Cell RNA - HHSteC [nTPM]":"46.5","Cell RNA - HL-60 [nTPM]":"8.0","Cell RNA - HMC-1 [nTPM]":"81.3","Cell RNA - HSkMC [nTPM]":"23.8","Cell RNA - hTCEpi [nTPM]":"14.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.2","Cell RNA - hTERT-HME1 [nTPM]":"15.4","Cell RNA - hTERT-RPE1 [nTPM]":"28.1","Cell RNA - HUVEC TERT2 [nTPM]":"22.2","Cell RNA - JURKAT [nTPM]":"18.7","Cell RNA - K-562 [nTPM]":"12.6","Cell RNA - Karpas-707 [nTPM]":"15.9","Cell RNA - LHCN-M2 [nTPM]":"16.6","Cell RNA - MCF7 [nTPM]":"15.1","Cell RNA - MOLT-4 [nTPM]":"7.8","Cell RNA - NB-4 [nTPM]":"7.9","Cell RNA - NTERA-2 [nTPM]":"9.8","Cell RNA - OE19 [nTPM]":"12.2","Cell RNA - PC-3 [nTPM]":"16.8","Cell RNA - REH [nTPM]":"16.4","Cell RNA - RH-30 [nTPM]":"9.3","Cell RNA - RPMI-8226 [nTPM]":"23.0","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"16.2","Cell RNA - SCLC-21H [nTPM]":"3.9","Cell RNA - SH-SY5Y [nTPM]":"17.2","Cell RNA - SiHa [nTPM]":"19.2","Cell RNA - SK-BR-3 [nTPM]":"24.4","Cell RNA - SK-MEL-30 [nTPM]":"20.3","Cell RNA - SuSa [nTPM]":"19.0","Cell RNA - T-47d [nTPM]":"17.1","Cell RNA - THP-1 [nTPM]":"7.7","Cell RNA - TIME [nTPM]":"24.2","Cell RNA - U-138 MG [nTPM]":"17.2","Cell RNA - U-2 OS [nTPM]":"11.6","Cell RNA - U-2197 [nTPM]":"40.3","Cell RNA - U-251 MG [nTPM]":"13.3","Cell RNA - U-266\/70 [nTPM]":"12.4","Cell RNA - U-266\/84 [nTPM]":"20.0","Cell RNA - U-698 [nTPM]":"4.2","Cell RNA - U-87 MG [nTPM]":"28.1","Cell RNA - U-937 [nTPM]":"7.8","Cell RNA - WM-115 [nTPM]":"11.8","Blood RNA - basophil [nTPM]":"27.9","Blood RNA - classical monocyte [nTPM]":"10.4","Blood RNA - eosinophil [nTPM]":"21.8","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"6.9","Blood RNA - MAIT T-cell [nTPM]":"4.9","Blood RNA - memory B-cell [nTPM]":"5.8","Blood RNA - memory CD4 T-cell [nTPM]":"4.0","Blood RNA - memory CD8 T-cell [nTPM]":"5.7","Blood RNA - myeloid DC [nTPM]":"9.7","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"3.1","Blood RNA - NK-cell [nTPM]":"5.2","Blood RNA - non-classical monocyte [nTPM]":"7.1","Blood RNA - plasmacytoid DC [nTPM]":"34.3","Blood RNA - T-reg [nTPM]":"4.3","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"17.0","Brain RNA - cerebellum [nTPM]":"13.5","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"10.3","Brain RNA - medulla oblongata [nTPM]":"16.5","Brain RNA - midbrain [nTPM]":"16.8","Brain RNA - pons [nTPM]":"18.0","Brain RNA - spinal cord [nTPM]":"10.9","Brain RNA - thalamus [nTPM]":"13.2","Brain RNA - white matter [nTPM]":"28.0","Single Cell Type RNA - Adipocytes [nTPM]":"4.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"4.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.1","Single Cell Type RNA - dendritic cells [nTPM]":"5.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.7","Single Cell Type RNA - Early spermatids [nTPM]":"35.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"5.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.3","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"6.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"7.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.2","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"29.3","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"12.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"10.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.5","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"3.3","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"4.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"19.7","Single Cell Type RNA - Spermatogonia [nTPM]":"8.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"30.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"CTSA","Gene synonym":["GSL","PPGB"],"Ensembl":"ENSG00000064601","Gene description":"Cathepsin A","Uniprot":["P10619"],"Chromosome":"20","Position":"45890144-45898824","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"368.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"445.6","Proximal enterocytes":"301.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"856.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB024930","HPA031068","HPA072487"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB024930":null,"HPA031068":"AB_10601205","HPA072487":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.95e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"80.4","Tissue RNA - adrenal gland [nTPM]":"368.3","Tissue RNA - amygdala [nTPM]":"56.8","Tissue RNA - appendix [nTPM]":"75.3","Tissue RNA - basal ganglia [nTPM]":"58.1","Tissue RNA - bone marrow [nTPM]":"75.6","Tissue RNA - breast [nTPM]":"61.9","Tissue RNA - cerebellum [nTPM]":"63.6","Tissue RNA - cerebral cortex [nTPM]":"65.6","Tissue RNA - cervix [nTPM]":"47.6","Tissue RNA - choroid plexus [nTPM]":"96.0","Tissue RNA - colon [nTPM]":"178.6","Tissue RNA - duodenum [nTPM]":"100.9","Tissue RNA - endometrium 1 [nTPM]":"55.1","Tissue RNA - epididymis [nTPM]":"39.0","Tissue RNA - esophagus [nTPM]":"60.4","Tissue RNA - fallopian tube [nTPM]":"39.3","Tissue RNA - gallbladder [nTPM]":"89.7","Tissue RNA - heart muscle [nTPM]":"97.2","Tissue RNA - hippocampal formation [nTPM]":"59.7","Tissue RNA - hypothalamus [nTPM]":"63.8","Tissue RNA - kidney [nTPM]":"188.1","Tissue RNA - liver [nTPM]":"95.7","Tissue RNA - lung [nTPM]":"90.9","Tissue RNA - lymph node [nTPM]":"61.6","Tissue RNA - medulla oblongata [nTPM]":"62.6","Tissue RNA - midbrain [nTPM]":"59.1","Tissue RNA - ovary [nTPM]":"62.2","Tissue RNA - pancreas [nTPM]":"52.9","Tissue RNA - parathyroid gland [nTPM]":"104.4","Tissue RNA - pituitary gland [nTPM]":"43.8","Tissue RNA - placenta [nTPM]":"76.4","Tissue RNA - pons [nTPM]":"61.4","Tissue RNA - prostate [nTPM]":"38.5","Tissue RNA - rectum [nTPM]":"170.4","Tissue RNA - retina [nTPM]":"44.0","Tissue RNA - salivary gland [nTPM]":"61.3","Tissue RNA - seminal vesicle [nTPM]":"48.4","Tissue RNA - skeletal muscle [nTPM]":"56.0","Tissue RNA - skin 1 [nTPM]":"95.2","Tissue RNA - small intestine [nTPM]":"109.2","Tissue RNA - smooth muscle [nTPM]":"67.3","Tissue RNA - spinal cord [nTPM]":"59.4","Tissue RNA - spleen [nTPM]":"108.5","Tissue RNA - stomach 1 [nTPM]":"63.3","Tissue RNA - testis [nTPM]":"33.5","Tissue RNA - thalamus [nTPM]":"70.2","Tissue RNA - thymus [nTPM]":"23.0","Tissue RNA - thyroid gland [nTPM]":"47.4","Tissue RNA - tongue [nTPM]":"61.7","Tissue RNA - tonsil [nTPM]":"58.8","Tissue RNA - urinary bladder [nTPM]":"82.8","Tissue RNA - vagina [nTPM]":"49.2","Tissue RNA - white matter [nTPM]":"68.4","Cell RNA - A-431 [nTPM]":"111.9","Cell RNA - A549 [nTPM]":"114.1","Cell RNA - AF22 [nTPM]":"17.6","Cell RNA - AN3-CA [nTPM]":"89.2","Cell RNA - ASC diff [nTPM]":"856.5","Cell RNA - ASC TERT1 [nTPM]":"438.6","Cell RNA - BEWO [nTPM]":"47.0","Cell RNA - BJ [nTPM]":"150.3","Cell RNA - BJ hTERT+ [nTPM]":"424.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"169.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"217.5","Cell RNA - CACO-2 [nTPM]":"214.4","Cell RNA - CAPAN-2 [nTPM]":"291.8","Cell RNA - Daudi [nTPM]":"24.1","Cell RNA - EFO-21 [nTPM]":"176.2","Cell RNA - fHDF\/TERT166 [nTPM]":"299.9","Cell RNA - GAMG [nTPM]":"638.1","Cell RNA - HaCaT [nTPM]":"168.6","Cell RNA - HAP1 [nTPM]":"55.9","Cell RNA - HBEC3-KT [nTPM]":"105.6","Cell RNA - HBF TERT88 [nTPM]":"95.7","Cell RNA - HDLM-2 [nTPM]":"47.6","Cell RNA - HEK 293 [nTPM]":"53.6","Cell RNA - HEL [nTPM]":"54.3","Cell RNA - HeLa [nTPM]":"53.4","Cell RNA - Hep G2 [nTPM]":"375.9","Cell RNA - HHSteC [nTPM]":"187.3","Cell RNA - HL-60 [nTPM]":"98.0","Cell RNA - HMC-1 [nTPM]":"240.9","Cell RNA - HSkMC [nTPM]":"349.0","Cell RNA - hTCEpi [nTPM]":"123.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"107.9","Cell RNA - hTERT-HME1 [nTPM]":"22.5","Cell RNA - hTERT-RPE1 [nTPM]":"421.9","Cell RNA - HUVEC TERT2 [nTPM]":"190.1","Cell RNA - JURKAT [nTPM]":"28.2","Cell RNA - K-562 [nTPM]":"61.0","Cell RNA - Karpas-707 [nTPM]":"355.1","Cell RNA - LHCN-M2 [nTPM]":"186.9","Cell RNA - MCF7 [nTPM]":"232.1","Cell RNA - MOLT-4 [nTPM]":"25.8","Cell RNA - NB-4 [nTPM]":"82.4","Cell RNA - NTERA-2 [nTPM]":"19.4","Cell RNA - OE19 [nTPM]":"172.6","Cell RNA - PC-3 [nTPM]":"272.1","Cell RNA - REH [nTPM]":"37.8","Cell RNA - RH-30 [nTPM]":"107.3","Cell RNA - RPMI-8226 [nTPM]":"135.7","Cell RNA - RPTEC TERT1 [nTPM]":"138.2","Cell RNA - RT4 [nTPM]":"96.7","Cell RNA - SCLC-21H [nTPM]":"36.9","Cell RNA - SH-SY5Y [nTPM]":"37.8","Cell RNA - SiHa [nTPM]":"263.2","Cell RNA - SK-BR-3 [nTPM]":"450.3","Cell RNA - SK-MEL-30 [nTPM]":"444.4","Cell RNA - SuSa [nTPM]":"51.5","Cell RNA - T-47d [nTPM]":"108.5","Cell RNA - THP-1 [nTPM]":"141.8","Cell RNA - TIME [nTPM]":"172.5","Cell RNA - U-138 MG [nTPM]":"335.0","Cell RNA - U-2 OS [nTPM]":"76.2","Cell RNA - U-2197 [nTPM]":"178.9","Cell RNA - U-251 MG [nTPM]":"123.7","Cell RNA - U-266\/70 [nTPM]":"162.1","Cell RNA - U-266\/84 [nTPM]":"238.5","Cell RNA - U-698 [nTPM]":"15.7","Cell RNA - U-87 MG [nTPM]":"599.3","Cell RNA - U-937 [nTPM]":"128.6","Cell RNA - WM-115 [nTPM]":"142.4","Blood RNA - basophil [nTPM]":"480.7","Blood RNA - classical monocyte [nTPM]":"305.9","Blood RNA - eosinophil [nTPM]":"530.5","Blood RNA - gdT-cell [nTPM]":"44.9","Blood RNA - intermediate monocyte [nTPM]":"168.8","Blood RNA - MAIT T-cell [nTPM]":"185.5","Blood RNA - memory B-cell [nTPM]":"42.0","Blood RNA - memory CD4 T-cell [nTPM]":"75.6","Blood RNA - memory CD8 T-cell [nTPM]":"78.3","Blood RNA - myeloid DC [nTPM]":"102.4","Blood RNA - naive B-cell [nTPM]":"25.7","Blood RNA - naive CD4 T-cell [nTPM]":"26.6","Blood RNA - naive CD8 T-cell [nTPM]":"39.8","Blood RNA - neutrophil [nTPM]":"152.4","Blood RNA - NK-cell [nTPM]":"81.2","Blood RNA - non-classical monocyte [nTPM]":"120.1","Blood RNA - plasmacytoid DC [nTPM]":"40.6","Blood RNA - T-reg [nTPM]":"155.4","Blood RNA - total PBMC [nTPM]":"378.1","Brain RNA - amygdala [nTPM]":"56.8","Brain RNA - basal ganglia [nTPM]":"58.1","Brain RNA - cerebellum [nTPM]":"63.6","Brain RNA - cerebral cortex [nTPM]":"65.6","Brain RNA - hippocampal formation [nTPM]":"59.7","Brain RNA - hypothalamus [nTPM]":"63.8","Brain RNA - medulla oblongata [nTPM]":"62.6","Brain RNA - midbrain [nTPM]":"59.1","Brain RNA - pons [nTPM]":"61.4","Brain RNA - spinal cord [nTPM]":"59.4","Brain RNA - thalamus [nTPM]":"70.2","Brain RNA - white matter [nTPM]":"68.4","Single Cell Type RNA - Adipocytes [nTPM]":"53.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.6","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"38.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"38.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"88.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"58.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"65.8","Single Cell Type RNA - Club cells [nTPM]":"64.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"104.1","Single Cell Type RNA - dendritic cells [nTPM]":"27.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"445.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"246.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.5","Single Cell Type RNA - Endothelial cells [nTPM]":"56.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"54.0","Single Cell Type RNA - Erythroid cells [nTPM]":"22.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"166.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"109.2","Single Cell Type RNA - Fibroblasts [nTPM]":"86.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.4","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"50.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"102.1","Single Cell Type RNA - Hepatocytes [nTPM]":"67.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"297.1","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"74.5","Single Cell Type RNA - Ionocytes [nTPM]":"95.6","Single Cell Type RNA - Kupffer cells [nTPM]":"177.1","Single Cell Type RNA - Langerhans cells [nTPM]":"25.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"32.9","Single Cell Type RNA - Macrophages [nTPM]":"273.1","Single Cell Type RNA - Melanocytes [nTPM]":"112.1","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"135.6","Single Cell Type RNA - Muller glia cells [nTPM]":"86.6","Single Cell Type RNA - NK-cells [nTPM]":"37.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"135.0","Single Cell Type RNA - Paneth cells [nTPM]":"216.0","Single Cell Type RNA - Peritubular cells [nTPM]":"27.4","Single Cell Type RNA - Plasma cells [nTPM]":"41.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"301.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"245.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"46.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"54.5","Single Cell Type RNA - Spermatocytes [nTPM]":"15.3","Single Cell Type RNA - Spermatogonia [nTPM]":"31.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"144.1","Single Cell Type RNA - T-cells [nTPM]":"49.1","Single Cell Type RNA - Theca cells [nTPM]":"91.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"113.9","Single Cell Type RNA - Urothelial cells [nTPM]":"36.2"},{"Gene":"CTSC","Gene synonym":["DPP1","PALS","PLS"],"Ensembl":"ENSG00000109861","Gene description":"Cathepsin C","Uniprot":["P53634"],"Chromosome":"11","Position":"88265069-88359684","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"900.7","Club cells":"471.8","Hofbauer cells":"1100.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"1078.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025364","HPA066610","HPA068434"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB025364":null,"HPA066610":"AB_2685694","HPA068434":"AB_2685989"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.30e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.80e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"173.2","Tissue RNA - adrenal gland [nTPM]":"60.7","Tissue RNA - amygdala [nTPM]":"9.9","Tissue RNA - appendix [nTPM]":"185.1","Tissue RNA - basal ganglia [nTPM]":"9.6","Tissue RNA - bone marrow [nTPM]":"71.7","Tissue RNA - breast [nTPM]":"63.4","Tissue RNA - cerebellum [nTPM]":"11.1","Tissue RNA - cerebral cortex [nTPM]":"24.9","Tissue RNA - cervix [nTPM]":"77.9","Tissue RNA - choroid plexus [nTPM]":"14.2","Tissue RNA - colon [nTPM]":"143.1","Tissue RNA - duodenum [nTPM]":"121.0","Tissue RNA - endometrium 1 [nTPM]":"43.9","Tissue RNA - epididymis [nTPM]":"28.5","Tissue RNA - esophagus [nTPM]":"63.3","Tissue RNA - fallopian tube [nTPM]":"54.0","Tissue RNA - gallbladder [nTPM]":"182.0","Tissue RNA - heart muscle [nTPM]":"38.5","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"10.1","Tissue RNA - kidney [nTPM]":"234.7","Tissue RNA - liver [nTPM]":"82.0","Tissue RNA - lung [nTPM]":"272.6","Tissue RNA - lymph node [nTPM]":"243.7","Tissue RNA - medulla oblongata [nTPM]":"14.0","Tissue RNA - midbrain [nTPM]":"11.9","Tissue RNA - ovary [nTPM]":"22.1","Tissue RNA - pancreas [nTPM]":"52.2","Tissue RNA - parathyroid gland [nTPM]":"42.4","Tissue RNA - pituitary gland [nTPM]":"39.3","Tissue RNA - placenta [nTPM]":"253.3","Tissue RNA - pons [nTPM]":"13.3","Tissue RNA - prostate [nTPM]":"26.0","Tissue RNA - rectum [nTPM]":"191.5","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"131.6","Tissue RNA - seminal vesicle [nTPM]":"28.9","Tissue RNA - skeletal muscle [nTPM]":"18.8","Tissue RNA - skin 1 [nTPM]":"29.6","Tissue RNA - small intestine [nTPM]":"128.8","Tissue RNA - smooth muscle [nTPM]":"88.9","Tissue RNA - spinal cord [nTPM]":"11.5","Tissue RNA - spleen [nTPM]":"197.2","Tissue RNA - stomach 1 [nTPM]":"73.6","Tissue RNA - testis [nTPM]":"22.8","Tissue RNA - thalamus [nTPM]":"19.5","Tissue RNA - thymus [nTPM]":"63.7","Tissue RNA - thyroid gland [nTPM]":"43.6","Tissue RNA - tongue [nTPM]":"31.9","Tissue RNA - tonsil [nTPM]":"140.6","Tissue RNA - urinary bladder [nTPM]":"176.3","Tissue RNA - vagina [nTPM]":"43.3","Tissue RNA - white matter [nTPM]":"21.3","Cell RNA - A-431 [nTPM]":"80.3","Cell RNA - A549 [nTPM]":"75.9","Cell RNA - AF22 [nTPM]":"27.6","Cell RNA - AN3-CA [nTPM]":"69.9","Cell RNA - ASC diff [nTPM]":"103.7","Cell RNA - ASC TERT1 [nTPM]":"286.1","Cell RNA - BEWO [nTPM]":"218.4","Cell RNA - BJ [nTPM]":"626.5","Cell RNA - BJ hTERT+ [nTPM]":"1078.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"372.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"270.3","Cell RNA - CACO-2 [nTPM]":"194.7","Cell RNA - CAPAN-2 [nTPM]":"361.3","Cell RNA - Daudi [nTPM]":"117.3","Cell RNA - EFO-21 [nTPM]":"278.9","Cell RNA - fHDF\/TERT166 [nTPM]":"365.2","Cell RNA - GAMG [nTPM]":"84.3","Cell RNA - HaCaT [nTPM]":"133.6","Cell RNA - HAP1 [nTPM]":"50.4","Cell RNA - HBEC3-KT [nTPM]":"269.2","Cell RNA - HBF TERT88 [nTPM]":"341.9","Cell RNA - HDLM-2 [nTPM]":"204.7","Cell RNA - HEK 293 [nTPM]":"82.8","Cell RNA - HEL [nTPM]":"144.5","Cell RNA - HeLa [nTPM]":"188.0","Cell RNA - Hep G2 [nTPM]":"233.5","Cell RNA - HHSteC [nTPM]":"140.2","Cell RNA - HL-60 [nTPM]":"188.9","Cell RNA - HMC-1 [nTPM]":"108.7","Cell RNA - HSkMC [nTPM]":"419.1","Cell RNA - hTCEpi [nTPM]":"198.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"284.5","Cell RNA - hTERT-HME1 [nTPM]":"697.4","Cell RNA - hTERT-RPE1 [nTPM]":"302.1","Cell RNA - HUVEC TERT2 [nTPM]":"377.6","Cell RNA - JURKAT [nTPM]":"122.3","Cell RNA - K-562 [nTPM]":"155.3","Cell RNA - Karpas-707 [nTPM]":"145.4","Cell RNA - LHCN-M2 [nTPM]":"54.8","Cell RNA - MCF7 [nTPM]":"14.8","Cell RNA - MOLT-4 [nTPM]":"89.1","Cell RNA - NB-4 [nTPM]":"295.1","Cell RNA - NTERA-2 [nTPM]":"172.2","Cell RNA - OE19 [nTPM]":"551.5","Cell RNA - PC-3 [nTPM]":"244.9","Cell RNA - REH [nTPM]":"113.6","Cell RNA - RH-30 [nTPM]":"30.7","Cell RNA - RPMI-8226 [nTPM]":"227.0","Cell RNA - RPTEC TERT1 [nTPM]":"451.3","Cell RNA - RT4 [nTPM]":"106.6","Cell RNA - SCLC-21H [nTPM]":"8.8","Cell RNA - SH-SY5Y [nTPM]":"66.8","Cell RNA - SiHa [nTPM]":"81.2","Cell RNA - SK-BR-3 [nTPM]":"114.9","Cell RNA - SK-MEL-30 [nTPM]":"80.6","Cell RNA - SuSa [nTPM]":"185.4","Cell RNA - T-47d [nTPM]":"27.9","Cell RNA - THP-1 [nTPM]":"152.7","Cell RNA - TIME [nTPM]":"149.3","Cell RNA - U-138 MG [nTPM]":"23.5","Cell RNA - U-2 OS [nTPM]":"190.5","Cell RNA - U-2197 [nTPM]":"156.8","Cell RNA - U-251 MG [nTPM]":"364.6","Cell RNA - U-266\/70 [nTPM]":"61.9","Cell RNA - U-266\/84 [nTPM]":"81.0","Cell RNA - U-698 [nTPM]":"122.9","Cell RNA - U-87 MG [nTPM]":"56.8","Cell RNA - U-937 [nTPM]":"435.8","Cell RNA - WM-115 [nTPM]":"122.4","Blood RNA - basophil [nTPM]":"85.5","Blood RNA - classical monocyte [nTPM]":"203.8","Blood RNA - eosinophil [nTPM]":"309.7","Blood RNA - gdT-cell [nTPM]":"230.1","Blood RNA - intermediate monocyte [nTPM]":"415.6","Blood RNA - MAIT T-cell [nTPM]":"194.9","Blood RNA - memory B-cell [nTPM]":"47.2","Blood RNA - memory CD4 T-cell [nTPM]":"99.6","Blood RNA - memory CD8 T-cell [nTPM]":"198.2","Blood RNA - myeloid DC [nTPM]":"209.9","Blood RNA - naive B-cell [nTPM]":"26.3","Blood RNA - naive CD4 T-cell [nTPM]":"49.5","Blood RNA - naive CD8 T-cell [nTPM]":"115.3","Blood RNA - neutrophil [nTPM]":"215.0","Blood RNA - NK-cell [nTPM]":"200.5","Blood RNA - non-classical monocyte [nTPM]":"582.9","Blood RNA - plasmacytoid DC [nTPM]":"425.0","Blood RNA - T-reg [nTPM]":"162.7","Blood RNA - total PBMC [nTPM]":"243.3","Brain RNA - amygdala [nTPM]":"9.9","Brain RNA - basal ganglia [nTPM]":"9.6","Brain RNA - cerebellum [nTPM]":"11.1","Brain RNA - cerebral cortex [nTPM]":"24.9","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"10.1","Brain RNA - medulla oblongata [nTPM]":"14.0","Brain RNA - midbrain [nTPM]":"11.9","Brain RNA - pons [nTPM]":"13.3","Brain RNA - spinal cord [nTPM]":"11.5","Brain RNA - thalamus [nTPM]":"19.5","Brain RNA - white matter [nTPM]":"21.3","Single Cell Type RNA - Adipocytes [nTPM]":"78.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"88.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"40.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"900.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"52.9","Single Cell Type RNA - Club cells [nTPM]":"471.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"414.1","Single Cell Type RNA - dendritic cells [nTPM]":"330.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"29.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"135.6","Single Cell Type RNA - Endothelial cells [nTPM]":"94.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"29.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"90.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"159.2","Single Cell Type RNA - Fibroblasts [nTPM]":"114.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.2","Single Cell Type RNA - granulocytes [nTPM]":"75.3","Single Cell Type RNA - Granulosa cells [nTPM]":"25.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"15.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"1100.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.4","Single Cell Type RNA - Ionocytes [nTPM]":"158.7","Single Cell Type RNA - Kupffer cells [nTPM]":"344.7","Single Cell Type RNA - Langerhans cells [nTPM]":"200.7","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"198.5","Single Cell Type RNA - Macrophages [nTPM]":"391.7","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"61.8","Single Cell Type RNA - monocytes [nTPM]":"185.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"299.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.8","Single Cell Type RNA - Paneth cells [nTPM]":"72.3","Single Cell Type RNA - Peritubular cells [nTPM]":"25.6","Single Cell Type RNA - Plasma cells [nTPM]":"78.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"166.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"93.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"150.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"11.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"227.3","Single Cell Type RNA - T-cells [nTPM]":"170.6","Single Cell Type RNA - Theca cells [nTPM]":"286.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"44.9","Single Cell Type RNA - Urothelial cells [nTPM]":"16.1"},{"Gene":"CTSD","Gene synonym":["CLN10","CPSD"],"Ensembl":"ENSG00000117984","Gene description":"Cathepsin D","Uniprot":["P07339"],"Chromosome":"11","Position":"1752752-1764573","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":["Alzheimer disease","Cancer-related genes","Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"1475.9","Hofbauer cells":"3763.5","Macrophages":"1512.6","Proximal enterocytes":"1699.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"2596.6","hTERT-RPE1":"2780.1","SK-BR-3":"2488.5"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000109","HPA003001"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000109":null,"HPA003001":"AB_1078404"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.46e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.93e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Tissue RNA - adipose tissue [nTPM]":"318.6","Tissue RNA - adrenal gland [nTPM]":"734.6","Tissue RNA - amygdala [nTPM]":"147.0","Tissue RNA - appendix [nTPM]":"204.9","Tissue RNA - basal ganglia [nTPM]":"181.9","Tissue RNA - bone marrow [nTPM]":"499.0","Tissue RNA - breast [nTPM]":"244.0","Tissue RNA - cerebellum [nTPM]":"186.0","Tissue RNA - cerebral cortex [nTPM]":"156.5","Tissue RNA - cervix [nTPM]":"270.8","Tissue RNA - choroid plexus [nTPM]":"672.7","Tissue RNA - colon [nTPM]":"298.0","Tissue RNA - duodenum [nTPM]":"387.6","Tissue RNA - endometrium 1 [nTPM]":"170.7","Tissue RNA - epididymis [nTPM]":"82.8","Tissue RNA - esophagus [nTPM]":"319.4","Tissue RNA - fallopian tube [nTPM]":"171.6","Tissue RNA - gallbladder [nTPM]":"438.4","Tissue RNA - heart muscle [nTPM]":"444.1","Tissue RNA - hippocampal formation [nTPM]":"187.8","Tissue RNA - hypothalamus [nTPM]":"223.6","Tissue RNA - kidney [nTPM]":"691.6","Tissue RNA - liver [nTPM]":"464.8","Tissue RNA - lung [nTPM]":"539.6","Tissue RNA - lymph node [nTPM]":"241.0","Tissue RNA - medulla oblongata [nTPM]":"247.6","Tissue RNA - midbrain [nTPM]":"206.6","Tissue RNA - ovary [nTPM]":"130.7","Tissue RNA - pancreas [nTPM]":"284.8","Tissue RNA - parathyroid gland [nTPM]":"137.3","Tissue RNA - pituitary gland [nTPM]":"131.5","Tissue RNA - placenta [nTPM]":"180.7","Tissue RNA - pons [nTPM]":"228.6","Tissue RNA - prostate [nTPM]":"138.2","Tissue RNA - rectum [nTPM]":"153.4","Tissue RNA - retina [nTPM]":"48.3","Tissue RNA - salivary gland [nTPM]":"422.1","Tissue RNA - seminal vesicle [nTPM]":"231.7","Tissue RNA - skeletal muscle [nTPM]":"590.3","Tissue RNA - skin 1 [nTPM]":"340.9","Tissue RNA - small intestine [nTPM]":"398.3","Tissue RNA - smooth muscle [nTPM]":"105.0","Tissue RNA - spinal cord [nTPM]":"188.9","Tissue RNA - spleen [nTPM]":"442.0","Tissue RNA - stomach 1 [nTPM]":"287.2","Tissue RNA - testis [nTPM]":"88.9","Tissue RNA - thalamus [nTPM]":"334.4","Tissue RNA - thymus [nTPM]":"78.1","Tissue RNA - thyroid gland [nTPM]":"182.1","Tissue RNA - tongue [nTPM]":"178.2","Tissue RNA - tonsil [nTPM]":"123.1","Tissue RNA - urinary bladder [nTPM]":"296.4","Tissue RNA - vagina [nTPM]":"307.5","Tissue RNA - white matter [nTPM]":"367.1","Cell RNA - A-431 [nTPM]":"204.6","Cell RNA - A549 [nTPM]":"578.9","Cell RNA - AF22 [nTPM]":"51.4","Cell RNA - AN3-CA [nTPM]":"246.2","Cell RNA - ASC diff [nTPM]":"586.5","Cell RNA - ASC TERT1 [nTPM]":"206.3","Cell RNA - BEWO [nTPM]":"112.1","Cell RNA - BJ [nTPM]":"149.4","Cell RNA - BJ hTERT+ [nTPM]":"362.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"161.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"182.8","Cell RNA - CACO-2 [nTPM]":"147.5","Cell RNA - CAPAN-2 [nTPM]":"2596.6","Cell RNA - Daudi [nTPM]":"49.2","Cell RNA - EFO-21 [nTPM]":"376.8","Cell RNA - fHDF\/TERT166 [nTPM]":"285.8","Cell RNA - GAMG [nTPM]":"1265.6","Cell RNA - HaCaT [nTPM]":"1072.2","Cell RNA - HAP1 [nTPM]":"63.7","Cell RNA - HBEC3-KT [nTPM]":"142.6","Cell RNA - HBF TERT88 [nTPM]":"35.8","Cell RNA - HDLM-2 [nTPM]":"206.7","Cell RNA - HEK 293 [nTPM]":"222.9","Cell RNA - HEL [nTPM]":"70.4","Cell RNA - HeLa [nTPM]":"92.5","Cell RNA - Hep G2 [nTPM]":"196.5","Cell RNA - HHSteC [nTPM]":"736.2","Cell RNA - HL-60 [nTPM]":"171.4","Cell RNA - HMC-1 [nTPM]":"787.7","Cell RNA - HSkMC [nTPM]":"350.9","Cell RNA - hTCEpi [nTPM]":"621.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"82.5","Cell RNA - hTERT-HME1 [nTPM]":"136.9","Cell RNA - hTERT-RPE1 [nTPM]":"2780.1","Cell RNA - HUVEC TERT2 [nTPM]":"128.2","Cell RNA - JURKAT [nTPM]":"62.1","Cell RNA - K-562 [nTPM]":"89.2","Cell RNA - Karpas-707 [nTPM]":"267.6","Cell RNA - LHCN-M2 [nTPM]":"263.3","Cell RNA - MCF7 [nTPM]":"832.6","Cell RNA - MOLT-4 [nTPM]":"47.0","Cell RNA - NB-4 [nTPM]":"110.9","Cell RNA - NTERA-2 [nTPM]":"153.1","Cell RNA - OE19 [nTPM]":"719.7","Cell RNA - PC-3 [nTPM]":"247.9","Cell RNA - REH [nTPM]":"62.5","Cell RNA - RH-30 [nTPM]":"72.5","Cell RNA - RPMI-8226 [nTPM]":"191.2","Cell RNA - RPTEC TERT1 [nTPM]":"586.6","Cell RNA - RT4 [nTPM]":"610.8","Cell RNA - SCLC-21H [nTPM]":"84.2","Cell RNA - SH-SY5Y [nTPM]":"94.8","Cell RNA - SiHa [nTPM]":"173.3","Cell RNA - SK-BR-3 [nTPM]":"2488.5","Cell RNA - SK-MEL-30 [nTPM]":"535.0","Cell RNA - SuSa [nTPM]":"68.6","Cell RNA - T-47d [nTPM]":"1022.8","Cell RNA - THP-1 [nTPM]":"232.6","Cell RNA - TIME [nTPM]":"170.3","Cell RNA - U-138 MG [nTPM]":"556.8","Cell RNA - U-2 OS [nTPM]":"92.9","Cell RNA - U-2197 [nTPM]":"79.0","Cell RNA - U-251 MG [nTPM]":"216.7","Cell RNA - U-266\/70 [nTPM]":"432.0","Cell RNA - U-266\/84 [nTPM]":"382.3","Cell RNA - U-698 [nTPM]":"26.8","Cell RNA - U-87 MG [nTPM]":"867.7","Cell RNA - U-937 [nTPM]":"468.6","Cell RNA - WM-115 [nTPM]":"509.6","Blood RNA - basophil [nTPM]":"211.2","Blood RNA - classical monocyte [nTPM]":"578.7","Blood RNA - eosinophil [nTPM]":"170.1","Blood RNA - gdT-cell [nTPM]":"156.5","Blood RNA - intermediate monocyte [nTPM]":"309.9","Blood RNA - MAIT T-cell [nTPM]":"90.6","Blood RNA - memory B-cell [nTPM]":"28.8","Blood RNA - memory CD4 T-cell [nTPM]":"72.1","Blood RNA - memory CD8 T-cell [nTPM]":"110.3","Blood RNA - myeloid DC [nTPM]":"144.5","Blood RNA - naive B-cell [nTPM]":"18.8","Blood RNA - naive CD4 T-cell [nTPM]":"82.5","Blood RNA - naive CD8 T-cell [nTPM]":"107.4","Blood RNA - neutrophil [nTPM]":"319.5","Blood RNA - NK-cell [nTPM]":"192.3","Blood RNA - non-classical monocyte [nTPM]":"265.2","Blood RNA - plasmacytoid DC [nTPM]":"120.3","Blood RNA - T-reg [nTPM]":"89.2","Blood RNA - total PBMC [nTPM]":"489.1","Brain RNA - amygdala [nTPM]":"147.0","Brain RNA - basal ganglia [nTPM]":"181.9","Brain RNA - cerebellum [nTPM]":"186.0","Brain RNA - cerebral cortex [nTPM]":"156.5","Brain RNA - hippocampal formation [nTPM]":"187.8","Brain RNA - hypothalamus [nTPM]":"223.6","Brain RNA - medulla oblongata [nTPM]":"247.6","Brain RNA - midbrain [nTPM]":"206.6","Brain RNA - pons [nTPM]":"228.6","Brain RNA - spinal cord [nTPM]":"188.9","Brain RNA - thalamus [nTPM]":"334.4","Brain RNA - white matter [nTPM]":"367.1","Single Cell Type RNA - Adipocytes [nTPM]":"139.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"112.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"228.6","Single Cell Type RNA - Astrocytes [nTPM]":"48.3","Single Cell Type RNA - B-cells [nTPM]":"62.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"72.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"223.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"473.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"71.7","Single Cell Type RNA - Bipolar cells [nTPM]":"168.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"108.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"113.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"251.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"314.5","Single Cell Type RNA - Club cells [nTPM]":"459.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"548.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"110.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"211.7","Single Cell Type RNA - dendritic cells [nTPM]":"156.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1475.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"109.5","Single Cell Type RNA - Ductal cells [nTPM]":"911.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"118.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"67.4","Single Cell Type RNA - Endothelial cells [nTPM]":"128.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"159.6","Single Cell Type RNA - Erythroid cells [nTPM]":"132.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"370.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"165.0","Single Cell Type RNA - Fibroblasts [nTPM]":"157.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"237.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"203.4","Single Cell Type RNA - granulocytes [nTPM]":"474.3","Single Cell Type RNA - Granulosa cells [nTPM]":"119.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"695.7","Single Cell Type RNA - Hepatocytes [nTPM]":"678.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"3763.5","Single Cell Type RNA - Horizontal cells [nTPM]":"264.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"418.2","Single Cell Type RNA - Ionocytes [nTPM]":"498.5","Single Cell Type RNA - Kupffer cells [nTPM]":"1187.8","Single Cell Type RNA - Langerhans cells [nTPM]":"67.5","Single Cell Type RNA - Late spermatids [nTPM]":"14.6","Single Cell Type RNA - Leydig cells [nTPM]":"108.4","Single Cell Type RNA - Macrophages [nTPM]":"1512.6","Single Cell Type RNA - Melanocytes [nTPM]":"227.7","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"382.6","Single Cell Type RNA - Muller glia cells [nTPM]":"179.0","Single Cell Type RNA - NK-cells [nTPM]":"256.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"392.3","Single Cell Type RNA - Paneth cells [nTPM]":"832.5","Single Cell Type RNA - Peritubular cells [nTPM]":"128.2","Single Cell Type RNA - Plasma cells [nTPM]":"122.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"111.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1699.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"311.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"270.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"102.1","Single Cell Type RNA - Sertoli cells [nTPM]":"111.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"70.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"135.2","Single Cell Type RNA - Spermatocytes [nTPM]":"26.6","Single Cell Type RNA - Spermatogonia [nTPM]":"63.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"141.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"82.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"471.3","Single Cell Type RNA - T-cells [nTPM]":"155.0","Single Cell Type RNA - Theca cells [nTPM]":"96.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"399.1","Single Cell Type RNA - Urothelial cells [nTPM]":"357.8"},{"Gene":"CTSF","Gene synonym":["CATSF","CLN13"],"Ensembl":"ENSG00000174080","Gene description":"Cathepsin F","Uniprot":["Q9UBX1"],"Chromosome":"11","Position":"66563464-66568879","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"320.9","Muller glia cells":"196.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SiHa":"23.1","SK-MEL-30":"59.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002141","HPA031431"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5800000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":["Endoplasmic reticulum","Plasma membrane"],"Antibody RRID":{"CAB002141":"AB_563471","HPA031431":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.92e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Tissue RNA - adipose tissue [nTPM]":"57.8","Tissue RNA - adrenal gland [nTPM]":"70.0","Tissue RNA - amygdala [nTPM]":"68.1","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"76.3","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"62.2","Tissue RNA - cerebellum [nTPM]":"74.5","Tissue RNA - cerebral cortex [nTPM]":"74.0","Tissue RNA - cervix [nTPM]":"78.8","Tissue RNA - choroid plexus [nTPM]":"90.2","Tissue RNA - colon [nTPM]":"76.7","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"89.2","Tissue RNA - epididymis [nTPM]":"21.9","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"70.8","Tissue RNA - gallbladder [nTPM]":"10.0","Tissue RNA - heart muscle [nTPM]":"100.2","Tissue RNA - hippocampal formation [nTPM]":"63.2","Tissue RNA - hypothalamus [nTPM]":"74.2","Tissue RNA - kidney [nTPM]":"46.9","Tissue RNA - liver [nTPM]":"66.0","Tissue RNA - lung [nTPM]":"32.9","Tissue RNA - lymph node [nTPM]":"3.6","Tissue RNA - medulla oblongata [nTPM]":"75.0","Tissue RNA - midbrain [nTPM]":"70.3","Tissue RNA - ovary [nTPM]":"99.1","Tissue RNA - pancreas [nTPM]":"31.7","Tissue RNA - parathyroid gland [nTPM]":"20.0","Tissue RNA - pituitary gland [nTPM]":"43.3","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"68.4","Tissue RNA - prostate [nTPM]":"53.5","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"26.2","Tissue RNA - salivary gland [nTPM]":"55.7","Tissue RNA - seminal vesicle [nTPM]":"17.1","Tissue RNA - skeletal muscle [nTPM]":"91.9","Tissue RNA - skin 1 [nTPM]":"44.4","Tissue RNA - small intestine [nTPM]":"29.5","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"77.2","Tissue RNA - spleen [nTPM]":"25.0","Tissue RNA - stomach 1 [nTPM]":"54.3","Tissue RNA - testis [nTPM]":"109.7","Tissue RNA - thalamus [nTPM]":"71.0","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"40.6","Tissue RNA - tongue [nTPM]":"27.6","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"56.6","Tissue RNA - vagina [nTPM]":"58.7","Tissue RNA - white matter [nTPM]":"86.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"17.0","Cell RNA - AF22 [nTPM]":"3.1","Cell RNA - AN3-CA [nTPM]":"5.4","Cell RNA - ASC diff [nTPM]":"14.2","Cell RNA - ASC TERT1 [nTPM]":"8.6","Cell RNA - BEWO [nTPM]":"3.4","Cell RNA - BJ [nTPM]":"13.0","Cell RNA - BJ hTERT+ [nTPM]":"11.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"2.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"21.3","Cell RNA - fHDF\/TERT166 [nTPM]":"10.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.2","Cell RNA - HAP1 [nTPM]":"6.8","Cell RNA - HBEC3-KT [nTPM]":"2.6","Cell RNA - HBF TERT88 [nTPM]":"4.8","Cell RNA - HDLM-2 [nTPM]":"3.7","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"7.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"9.9","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"4.4","Cell RNA - HSkMC [nTPM]":"22.3","Cell RNA - hTCEpi [nTPM]":"9.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"1.6","Cell RNA - hTERT-RPE1 [nTPM]":"13.7","Cell RNA - HUVEC TERT2 [nTPM]":"3.8","Cell RNA - JURKAT [nTPM]":"2.0","Cell RNA - K-562 [nTPM]":"5.4","Cell RNA - Karpas-707 [nTPM]":"1.6","Cell RNA - LHCN-M2 [nTPM]":"5.2","Cell RNA - MCF7 [nTPM]":"4.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"1.7","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"3.7","Cell RNA - PC-3 [nTPM]":"9.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.5","Cell RNA - RPTEC TERT1 [nTPM]":"7.1","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"4.3","Cell RNA - SH-SY5Y [nTPM]":"6.9","Cell RNA - SiHa [nTPM]":"23.1","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"59.5","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"7.4","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"3.3","Cell RNA - U-138 MG [nTPM]":"1.8","Cell RNA - U-2 OS [nTPM]":"2.9","Cell RNA - U-2197 [nTPM]":"1.5","Cell RNA - U-251 MG [nTPM]":"1.2","Cell RNA - U-266\/70 [nTPM]":"21.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"4.1","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"6.4","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"4.6","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"68.1","Brain RNA - basal ganglia [nTPM]":"76.3","Brain RNA - cerebellum [nTPM]":"74.5","Brain RNA - cerebral cortex [nTPM]":"74.0","Brain RNA - hippocampal formation [nTPM]":"63.2","Brain RNA - hypothalamus [nTPM]":"74.2","Brain RNA - medulla oblongata [nTPM]":"75.0","Brain RNA - midbrain [nTPM]":"70.3","Brain RNA - pons [nTPM]":"68.4","Brain RNA - spinal cord [nTPM]":"77.2","Brain RNA - thalamus [nTPM]":"71.0","Brain RNA - white matter [nTPM]":"86.6","Single Cell Type RNA - Adipocytes [nTPM]":"36.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.6","Single Cell Type RNA - Astrocytes [nTPM]":"31.3","Single Cell Type RNA - B-cells [nTPM]":"5.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"62.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"37.5","Single Cell Type RNA - Bipolar cells [nTPM]":"107.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"80.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"57.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"7.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.6","Single Cell Type RNA - dendritic cells [nTPM]":"9.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"13.1","Single Cell Type RNA - Early spermatids [nTPM]":"163.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.8","Single Cell Type RNA - Endothelial cells [nTPM]":"27.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"11.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.5","Single Cell Type RNA - Fibroblasts [nTPM]":"118.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.3","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"52.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"56.0","Single Cell Type RNA - Hepatocytes [nTPM]":"67.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.9","Single Cell Type RNA - Horizontal cells [nTPM]":"134.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.1","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"21.5","Single Cell Type RNA - Langerhans cells [nTPM]":"32.8","Single Cell Type RNA - Late spermatids [nTPM]":"320.9","Single Cell Type RNA - Leydig cells [nTPM]":"145.7","Single Cell Type RNA - Macrophages [nTPM]":"13.1","Single Cell Type RNA - Melanocytes [nTPM]":"156.5","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"3.1","Single Cell Type RNA - Muller glia cells [nTPM]":"196.6","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.9","Single Cell Type RNA - Paneth cells [nTPM]":"3.2","Single Cell Type RNA - Peritubular cells [nTPM]":"121.9","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"50.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"44.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"77.9","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"62.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.9","Single Cell Type RNA - Spermatocytes [nTPM]":"169.6","Single Cell Type RNA - Spermatogonia [nTPM]":"43.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.7","Single Cell Type RNA - T-cells [nTPM]":"9.5","Single Cell Type RNA - Theca cells [nTPM]":"30.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"32.9"},{"Gene":"CTSK","Gene synonym":["CTSO","CTSO2","PKND","PYCD"],"Ensembl":"ENSG00000143387","Gene description":"Cathepsin K","Uniprot":["P43235"],"Chromosome":"1","Position":"150794880-150809577","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"420.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"372.4","Langerhans cells":"123.6","Leydig cells":"119.0","Melanocytes":"97.8","Peritubular cells":"149.7","Theca cells":"80.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"18.1"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"monocytes":"1.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"ASC diff":"2284.0","ASC TERT1":"813.2","BJ hTERT+":"1949.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050346"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA050346":"AB_2681101"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"224.1","Tissue RNA - adrenal gland [nTPM]":"12.5","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"33.1","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"3.1","Tissue RNA - breast [nTPM]":"227.7","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"18.1","Tissue RNA - cervix [nTPM]":"420.6","Tissue RNA - choroid plexus [nTPM]":"16.4","Tissue RNA - colon [nTPM]":"68.6","Tissue RNA - duodenum [nTPM]":"13.8","Tissue RNA - endometrium 1 [nTPM]":"334.0","Tissue RNA - epididymis [nTPM]":"44.9","Tissue RNA - esophagus [nTPM]":"46.0","Tissue RNA - fallopian tube [nTPM]":"74.0","Tissue RNA - gallbladder [nTPM]":"299.2","Tissue RNA - heart muscle [nTPM]":"35.8","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"12.7","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"36.4","Tissue RNA - lymph node [nTPM]":"42.1","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"78.4","Tissue RNA - pancreas [nTPM]":"10.6","Tissue RNA - parathyroid gland [nTPM]":"6.1","Tissue RNA - pituitary gland [nTPM]":"14.6","Tissue RNA - placenta [nTPM]":"18.9","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"34.1","Tissue RNA - rectum [nTPM]":"61.8","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"53.3","Tissue RNA - seminal vesicle [nTPM]":"38.0","Tissue RNA - skeletal muscle [nTPM]":"15.7","Tissue RNA - skin 1 [nTPM]":"219.8","Tissue RNA - small intestine [nTPM]":"63.8","Tissue RNA - smooth muscle [nTPM]":"141.6","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"20.2","Tissue RNA - stomach 1 [nTPM]":"41.7","Tissue RNA - testis [nTPM]":"15.1","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"34.7","Tissue RNA - tongue [nTPM]":"46.3","Tissue RNA - tonsil [nTPM]":"48.7","Tissue RNA - urinary bladder [nTPM]":"210.5","Tissue RNA - vagina [nTPM]":"176.2","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"1.4","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"2284.0","Cell RNA - ASC TERT1 [nTPM]":"813.2","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"55.2","Cell RNA - BJ hTERT+ [nTPM]":"1949.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.3","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"129.8","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"11.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"156.5","Cell RNA - hTCEpi [nTPM]":"1.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.5","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"137.6","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"1.4","Cell RNA - LHCN-M2 [nTPM]":"1.5","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"3.0","Cell RNA - NTERA-2 [nTPM]":"10.2","Cell RNA - OE19 [nTPM]":"1.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"3.2","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"2.9","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"29.3","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"1.7","Cell RNA - U-698 [nTPM]":"3.6","Cell RNA - U-87 MG [nTPM]":"184.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"9.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"18.1","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"17.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"68.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"12.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.3","Single Cell Type RNA - dendritic cells [nTPM]":"2.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"59.0","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.5","Single Cell Type RNA - Fibroblasts [nTPM]":"372.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"77.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.4","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.6","Single Cell Type RNA - Langerhans cells [nTPM]":"123.6","Single Cell Type RNA - Late spermatids [nTPM]":"4.4","Single Cell Type RNA - Leydig cells [nTPM]":"119.0","Single Cell Type RNA - Macrophages [nTPM]":"8.7","Single Cell Type RNA - Melanocytes [nTPM]":"97.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.7","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"149.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"5.4","Single Cell Type RNA - Theca cells [nTPM]":"80.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"DNAJC5","Gene synonym":["CLN4","DNAJC5A","FLJ00118","FLJ13070"],"Ensembl":"ENSG00000101152","Gene description":"DnaJ heat shock protein family (Hsp40) member C5","Uniprot":["Q9H3Z4"],"Chromosome":"20","Position":"63895126-63936031","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"123.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012139","HPA012737","HPA013154"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA012139":null,"HPA012737":"AB_1847293","HPA013154":"AB_1847292"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.82e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.70e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.6","Tissue RNA - adrenal gland [nTPM]":"22.1","Tissue RNA - amygdala [nTPM]":"30.8","Tissue RNA - appendix [nTPM]":"10.7","Tissue RNA - basal ganglia [nTPM]":"33.0","Tissue RNA - bone marrow [nTPM]":"16.9","Tissue RNA - breast [nTPM]":"11.1","Tissue RNA - cerebellum [nTPM]":"10.2","Tissue RNA - cerebral cortex [nTPM]":"39.1","Tissue RNA - cervix [nTPM]":"11.4","Tissue RNA - choroid plexus [nTPM]":"2.1","Tissue RNA - colon [nTPM]":"17.6","Tissue RNA - duodenum [nTPM]":"11.5","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"5.7","Tissue RNA - esophagus [nTPM]":"42.0","Tissue RNA - fallopian tube [nTPM]":"11.6","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"25.8","Tissue RNA - hippocampal formation [nTPM]":"36.2","Tissue RNA - hypothalamus [nTPM]":"31.0","Tissue RNA - kidney [nTPM]":"17.7","Tissue RNA - liver [nTPM]":"12.8","Tissue RNA - lung [nTPM]":"18.0","Tissue RNA - lymph node [nTPM]":"9.9","Tissue RNA - medulla oblongata [nTPM]":"27.9","Tissue RNA - midbrain [nTPM]":"23.9","Tissue RNA - ovary [nTPM]":"8.8","Tissue RNA - pancreas [nTPM]":"22.7","Tissue RNA - parathyroid gland [nTPM]":"21.2","Tissue RNA - pituitary gland [nTPM]":"28.5","Tissue RNA - placenta [nTPM]":"8.4","Tissue RNA - pons [nTPM]":"30.4","Tissue RNA - prostate [nTPM]":"16.7","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"28.1","Tissue RNA - salivary gland [nTPM]":"16.2","Tissue RNA - seminal vesicle [nTPM]":"11.5","Tissue RNA - skeletal muscle [nTPM]":"14.5","Tissue RNA - skin 1 [nTPM]":"19.2","Tissue RNA - small intestine [nTPM]":"17.5","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"20.8","Tissue RNA - testis [nTPM]":"10.7","Tissue RNA - thalamus [nTPM]":"26.8","Tissue RNA - thymus [nTPM]":"8.4","Tissue RNA - thyroid gland [nTPM]":"16.8","Tissue RNA - tongue [nTPM]":"9.5","Tissue RNA - tonsil [nTPM]":"8.5","Tissue RNA - urinary bladder [nTPM]":"13.4","Tissue RNA - vagina [nTPM]":"16.9","Tissue RNA - white matter [nTPM]":"25.7","Cell RNA - A-431 [nTPM]":"25.2","Cell RNA - A549 [nTPM]":"23.7","Cell RNA - AF22 [nTPM]":"19.8","Cell RNA - AN3-CA [nTPM]":"18.8","Cell RNA - ASC diff [nTPM]":"19.4","Cell RNA - ASC TERT1 [nTPM]":"15.9","Cell RNA - BEWO [nTPM]":"14.6","Cell RNA - BJ [nTPM]":"28.6","Cell RNA - BJ hTERT+ [nTPM]":"27.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.8","Cell RNA - CACO-2 [nTPM]":"52.7","Cell RNA - CAPAN-2 [nTPM]":"30.2","Cell RNA - Daudi [nTPM]":"9.8","Cell RNA - EFO-21 [nTPM]":"31.6","Cell RNA - fHDF\/TERT166 [nTPM]":"28.2","Cell RNA - GAMG [nTPM]":"22.7","Cell RNA - HaCaT [nTPM]":"36.4","Cell RNA - HAP1 [nTPM]":"15.9","Cell RNA - HBEC3-KT [nTPM]":"53.6","Cell RNA - HBF TERT88 [nTPM]":"16.0","Cell RNA - HDLM-2 [nTPM]":"8.2","Cell RNA - HEK 293 [nTPM]":"11.3","Cell RNA - HEL [nTPM]":"19.3","Cell RNA - HeLa [nTPM]":"17.4","Cell RNA - Hep G2 [nTPM]":"25.8","Cell RNA - HHSteC [nTPM]":"18.1","Cell RNA - HL-60 [nTPM]":"19.2","Cell RNA - HMC-1 [nTPM]":"43.5","Cell RNA - HSkMC [nTPM]":"18.0","Cell RNA - hTCEpi [nTPM]":"39.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.9","Cell RNA - hTERT-HME1 [nTPM]":"11.7","Cell RNA - hTERT-RPE1 [nTPM]":"19.1","Cell RNA - HUVEC TERT2 [nTPM]":"24.2","Cell RNA - JURKAT [nTPM]":"16.5","Cell RNA - K-562 [nTPM]":"19.2","Cell RNA - Karpas-707 [nTPM]":"8.9","Cell RNA - LHCN-M2 [nTPM]":"22.6","Cell RNA - MCF7 [nTPM]":"17.3","Cell RNA - MOLT-4 [nTPM]":"21.1","Cell RNA - NB-4 [nTPM]":"30.9","Cell RNA - NTERA-2 [nTPM]":"7.1","Cell RNA - OE19 [nTPM]":"21.0","Cell RNA - PC-3 [nTPM]":"26.5","Cell RNA - REH [nTPM]":"21.0","Cell RNA - RH-30 [nTPM]":"10.9","Cell RNA - RPMI-8226 [nTPM]":"10.7","Cell RNA - RPTEC TERT1 [nTPM]":"16.4","Cell RNA - RT4 [nTPM]":"22.6","Cell RNA - SCLC-21H [nTPM]":"21.4","Cell RNA - SH-SY5Y [nTPM]":"13.9","Cell RNA - SiHa [nTPM]":"30.8","Cell RNA - SK-BR-3 [nTPM]":"48.7","Cell RNA - SK-MEL-30 [nTPM]":"17.8","Cell RNA - SuSa [nTPM]":"11.6","Cell RNA - T-47d [nTPM]":"23.5","Cell RNA - THP-1 [nTPM]":"75.9","Cell RNA - TIME [nTPM]":"43.7","Cell RNA - U-138 MG [nTPM]":"42.6","Cell RNA - U-2 OS [nTPM]":"14.4","Cell RNA - U-2197 [nTPM]":"20.4","Cell RNA - U-251 MG [nTPM]":"21.5","Cell RNA - U-266\/70 [nTPM]":"11.1","Cell RNA - U-266\/84 [nTPM]":"5.6","Cell RNA - U-698 [nTPM]":"13.6","Cell RNA - U-87 MG [nTPM]":"42.9","Cell RNA - U-937 [nTPM]":"25.3","Cell RNA - WM-115 [nTPM]":"25.4","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"3.2","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"3.1","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"3.1","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"30.8","Brain RNA - basal ganglia [nTPM]":"33.0","Brain RNA - cerebellum [nTPM]":"10.2","Brain RNA - cerebral cortex [nTPM]":"39.1","Brain RNA - hippocampal formation [nTPM]":"36.2","Brain RNA - hypothalamus [nTPM]":"31.0","Brain RNA - medulla oblongata [nTPM]":"27.9","Brain RNA - midbrain [nTPM]":"23.9","Brain RNA - pons [nTPM]":"30.4","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"26.8","Brain RNA - white matter [nTPM]":"25.7","Single Cell Type RNA - Adipocytes [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.8","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"10.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"60.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"23.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.5","Single Cell Type RNA - dendritic cells [nTPM]":"19.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"71.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"20.5","Single Cell Type RNA - Early spermatids [nTPM]":"48.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.5","Single Cell Type RNA - Endothelial cells [nTPM]":"18.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"32.4","Single Cell Type RNA - Erythroid cells [nTPM]":"10.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.4","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"12.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.9","Single Cell Type RNA - Hepatocytes [nTPM]":"27.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"43.5","Single Cell Type RNA - Horizontal cells [nTPM]":"79.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"38.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.3","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"51.0","Single Cell Type RNA - Langerhans cells [nTPM]":"24.8","Single Cell Type RNA - Late spermatids [nTPM]":"123.5","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"31.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"36.9","Single Cell Type RNA - Muller glia cells [nTPM]":"27.9","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"59.0","Single Cell Type RNA - Paneth cells [nTPM]":"41.1","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"17.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"62.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"47.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.1","Single Cell Type RNA - Spermatocytes [nTPM]":"13.5","Single Cell Type RNA - Spermatogonia [nTPM]":"13.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.2","Single Cell Type RNA - T-cells [nTPM]":"15.0","Single Cell Type RNA - Theca cells [nTPM]":"13.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.4","Single Cell Type RNA - Urothelial cells [nTPM]":"64.5"},{"Gene":"FUCA1","Gene synonym":[],"Ensembl":"ENSG00000179163","Gene description":"Alpha-L-fucosidase 1","Uniprot":["P04066"],"Chromosome":"1","Position":"23845077-23868290","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"181.7","Distal enterocytes":"226.6","Paneth cells":"221.0","Proximal enterocytes":"210.9","Syncytiotrophoblasts":"200.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"165.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046542","HPA056371"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"60000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046542":"AB_2679691","HPA056371":"AB_2683108"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.45e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.70e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Tissue RNA - adipose tissue [nTPM]":"34.2","Tissue RNA - adrenal gland [nTPM]":"34.4","Tissue RNA - amygdala [nTPM]":"8.3","Tissue RNA - appendix [nTPM]":"49.8","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"7.7","Tissue RNA - breast [nTPM]":"26.3","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"11.2","Tissue RNA - cervix [nTPM]":"54.5","Tissue RNA - choroid plexus [nTPM]":"23.8","Tissue RNA - colon [nTPM]":"124.2","Tissue RNA - duodenum [nTPM]":"90.3","Tissue RNA - endometrium 1 [nTPM]":"20.7","Tissue RNA - epididymis [nTPM]":"113.0","Tissue RNA - esophagus [nTPM]":"17.0","Tissue RNA - fallopian tube [nTPM]":"51.1","Tissue RNA - gallbladder [nTPM]":"46.6","Tissue RNA - heart muscle [nTPM]":"20.6","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"78.2","Tissue RNA - liver [nTPM]":"104.8","Tissue RNA - lung [nTPM]":"55.1","Tissue RNA - lymph node [nTPM]":"168.2","Tissue RNA - medulla oblongata [nTPM]":"9.5","Tissue RNA - midbrain [nTPM]":"8.8","Tissue RNA - ovary [nTPM]":"23.8","Tissue RNA - pancreas [nTPM]":"23.9","Tissue RNA - parathyroid gland [nTPM]":"56.9","Tissue RNA - pituitary gland [nTPM]":"17.6","Tissue RNA - placenta [nTPM]":"72.6","Tissue RNA - pons [nTPM]":"9.6","Tissue RNA - prostate [nTPM]":"50.2","Tissue RNA - rectum [nTPM]":"140.7","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"40.8","Tissue RNA - seminal vesicle [nTPM]":"60.4","Tissue RNA - skeletal muscle [nTPM]":"15.8","Tissue RNA - skin 1 [nTPM]":"14.9","Tissue RNA - small intestine [nTPM]":"81.3","Tissue RNA - smooth muscle [nTPM]":"26.7","Tissue RNA - spinal cord [nTPM]":"9.3","Tissue RNA - spleen [nTPM]":"71.8","Tissue RNA - stomach 1 [nTPM]":"63.9","Tissue RNA - testis [nTPM]":"27.7","Tissue RNA - thalamus [nTPM]":"10.8","Tissue RNA - thymus [nTPM]":"26.8","Tissue RNA - thyroid gland [nTPM]":"70.6","Tissue RNA - tongue [nTPM]":"17.7","Tissue RNA - tonsil [nTPM]":"94.1","Tissue RNA - urinary bladder [nTPM]":"74.9","Tissue RNA - vagina [nTPM]":"13.2","Tissue RNA - white matter [nTPM]":"12.8","Cell RNA - A-431 [nTPM]":"15.9","Cell RNA - A549 [nTPM]":"10.6","Cell RNA - AF22 [nTPM]":"2.2","Cell RNA - AN3-CA [nTPM]":"31.9","Cell RNA - ASC diff [nTPM]":"4.2","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"11.0","Cell RNA - BJ [nTPM]":"16.6","Cell RNA - BJ hTERT+ [nTPM]":"34.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.6","Cell RNA - CACO-2 [nTPM]":"14.5","Cell RNA - CAPAN-2 [nTPM]":"165.1","Cell RNA - Daudi [nTPM]":"23.9","Cell RNA - EFO-21 [nTPM]":"40.9","Cell RNA - fHDF\/TERT166 [nTPM]":"21.3","Cell RNA - GAMG [nTPM]":"18.8","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"15.3","Cell RNA - HBEC3-KT [nTPM]":"35.4","Cell RNA - HBF TERT88 [nTPM]":"22.4","Cell RNA - HDLM-2 [nTPM]":"16.9","Cell RNA - HEK 293 [nTPM]":"25.6","Cell RNA - HEL [nTPM]":"19.7","Cell RNA - HeLa [nTPM]":"9.2","Cell RNA - Hep G2 [nTPM]":"32.7","Cell RNA - HHSteC [nTPM]":"14.2","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"62.7","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"19.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.2","Cell RNA - hTERT-HME1 [nTPM]":"8.1","Cell RNA - hTERT-RPE1 [nTPM]":"55.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.9","Cell RNA - JURKAT [nTPM]":"13.3","Cell RNA - K-562 [nTPM]":"9.3","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"20.6","Cell RNA - MCF7 [nTPM]":"17.5","Cell RNA - MOLT-4 [nTPM]":"5.0","Cell RNA - NB-4 [nTPM]":"17.7","Cell RNA - NTERA-2 [nTPM]":"5.4","Cell RNA - OE19 [nTPM]":"48.1","Cell RNA - PC-3 [nTPM]":"16.9","Cell RNA - REH [nTPM]":"26.9","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"26.2","Cell RNA - RPTEC TERT1 [nTPM]":"63.5","Cell RNA - RT4 [nTPM]":"40.5","Cell RNA - SCLC-21H [nTPM]":"10.9","Cell RNA - SH-SY5Y [nTPM]":"10.6","Cell RNA - SiHa [nTPM]":"47.9","Cell RNA - SK-BR-3 [nTPM]":"18.5","Cell RNA - SK-MEL-30 [nTPM]":"26.2","Cell RNA - SuSa [nTPM]":"17.9","Cell RNA - T-47d [nTPM]":"13.6","Cell RNA - THP-1 [nTPM]":"7.8","Cell RNA - TIME [nTPM]":"1.8","Cell RNA - U-138 MG [nTPM]":"5.8","Cell RNA - U-2 OS [nTPM]":"9.0","Cell RNA - U-2197 [nTPM]":"38.9","Cell RNA - U-251 MG [nTPM]":"5.6","Cell RNA - U-266\/70 [nTPM]":"28.5","Cell RNA - U-266\/84 [nTPM]":"31.0","Cell RNA - U-698 [nTPM]":"8.5","Cell RNA - U-87 MG [nTPM]":"14.5","Cell RNA - U-937 [nTPM]":"58.9","Cell RNA - WM-115 [nTPM]":"9.5","Blood RNA - basophil [nTPM]":"54.8","Blood RNA - classical monocyte [nTPM]":"100.4","Blood RNA - eosinophil [nTPM]":"51.9","Blood RNA - gdT-cell [nTPM]":"27.2","Blood RNA - intermediate monocyte [nTPM]":"99.9","Blood RNA - MAIT T-cell [nTPM]":"23.1","Blood RNA - memory B-cell [nTPM]":"23.8","Blood RNA - memory CD4 T-cell [nTPM]":"19.5","Blood RNA - memory CD8 T-cell [nTPM]":"22.9","Blood RNA - myeloid DC [nTPM]":"44.0","Blood RNA - naive B-cell [nTPM]":"14.1","Blood RNA - naive CD4 T-cell [nTPM]":"18.9","Blood RNA - naive CD8 T-cell [nTPM]":"22.0","Blood RNA - neutrophil [nTPM]":"12.8","Blood RNA - NK-cell [nTPM]":"44.6","Blood RNA - non-classical monocyte [nTPM]":"91.1","Blood RNA - plasmacytoid DC [nTPM]":"25.4","Blood RNA - T-reg [nTPM]":"21.4","Blood RNA - total PBMC [nTPM]":"64.8","Brain RNA - amygdala [nTPM]":"8.3","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"11.2","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"9.5","Brain RNA - midbrain [nTPM]":"8.8","Brain RNA - pons [nTPM]":"9.6","Brain RNA - spinal cord [nTPM]":"9.3","Brain RNA - thalamus [nTPM]":"10.8","Brain RNA - white matter [nTPM]":"12.8","Single Cell Type RNA - Adipocytes [nTPM]":"12.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.6","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"10.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"99.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"77.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"84.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"181.7","Single Cell Type RNA - dendritic cells [nTPM]":"13.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"226.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"64.1","Single Cell Type RNA - Early spermatids [nTPM]":"61.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.8","Single Cell Type RNA - Endothelial cells [nTPM]":"11.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"20.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"50.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.2","Single Cell Type RNA - Fibroblasts [nTPM]":"16.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.3","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"11.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.7","Single Cell Type RNA - Hepatocytes [nTPM]":"42.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"156.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.4","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"121.0","Single Cell Type RNA - Langerhans cells [nTPM]":"13.5","Single Cell Type RNA - Late spermatids [nTPM]":"24.4","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"85.4","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"29.6","Single Cell Type RNA - Muller glia cells [nTPM]":"13.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.9","Single Cell Type RNA - Paneth cells [nTPM]":"221.0","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"210.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.2","Single Cell Type RNA - Spermatocytes [nTPM]":"109.0","Single Cell Type RNA - Spermatogonia [nTPM]":"24.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"200.6","Single Cell Type RNA - T-cells [nTPM]":"11.2","Single Cell Type RNA - Theca cells [nTPM]":"34.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"79.5","Single Cell Type RNA - Urothelial cells [nTPM]":"40.3"},{"Gene":"GALC","Gene synonym":[],"Ensembl":"ENSG00000054983","Gene description":"Galactosylceramidase","Uniprot":["P54803"],"Chromosome":"14","Position":"87837820-87993665","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"68.4","Kupffer cells":"72.1","Late spermatids":"77.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"84.3","HMC-1":"78.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022196"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"53000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022196":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.0","Tissue RNA - adrenal gland [nTPM]":"17.2","Tissue RNA - amygdala [nTPM]":"20.0","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"23.3","Tissue RNA - bone marrow [nTPM]":"23.2","Tissue RNA - breast [nTPM]":"13.3","Tissue RNA - cerebellum [nTPM]":"22.1","Tissue RNA - cerebral cortex [nTPM]":"26.1","Tissue RNA - cervix [nTPM]":"12.0","Tissue RNA - choroid plexus [nTPM]":"20.8","Tissue RNA - colon [nTPM]":"15.1","Tissue RNA - duodenum [nTPM]":"33.3","Tissue RNA - endometrium 1 [nTPM]":"11.1","Tissue RNA - epididymis [nTPM]":"12.2","Tissue RNA - esophagus [nTPM]":"6.6","Tissue RNA - fallopian tube [nTPM]":"20.7","Tissue RNA - gallbladder [nTPM]":"18.4","Tissue RNA - heart muscle [nTPM]":"13.5","Tissue RNA - hippocampal formation [nTPM]":"18.5","Tissue RNA - hypothalamus [nTPM]":"21.6","Tissue RNA - kidney [nTPM]":"21.3","Tissue RNA - liver [nTPM]":"12.1","Tissue RNA - lung [nTPM]":"23.9","Tissue RNA - lymph node [nTPM]":"11.7","Tissue RNA - medulla oblongata [nTPM]":"23.0","Tissue RNA - midbrain [nTPM]":"22.6","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"10.8","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"16.8","Tissue RNA - pons [nTPM]":"23.9","Tissue RNA - prostate [nTPM]":"14.3","Tissue RNA - rectum [nTPM]":"17.3","Tissue RNA - retina [nTPM]":"18.4","Tissue RNA - salivary gland [nTPM]":"8.1","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"8.0","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"34.4","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"22.3","Tissue RNA - spleen [nTPM]":"15.4","Tissue RNA - stomach 1 [nTPM]":"16.4","Tissue RNA - testis [nTPM]":"24.0","Tissue RNA - thalamus [nTPM]":"20.8","Tissue RNA - thymus [nTPM]":"9.7","Tissue RNA - thyroid gland [nTPM]":"24.5","Tissue RNA - tongue [nTPM]":"12.9","Tissue RNA - tonsil [nTPM]":"7.9","Tissue RNA - urinary bladder [nTPM]":"13.6","Tissue RNA - vagina [nTPM]":"7.5","Tissue RNA - white matter [nTPM]":"30.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"19.5","Cell RNA - AF22 [nTPM]":"7.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"23.8","Cell RNA - ASC TERT1 [nTPM]":"21.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"9.1","Cell RNA - BJ hTERT+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.9","Cell RNA - CACO-2 [nTPM]":"10.8","Cell RNA - CAPAN-2 [nTPM]":"84.3","Cell RNA - Daudi [nTPM]":"5.3","Cell RNA - EFO-21 [nTPM]":"26.4","Cell RNA - fHDF\/TERT166 [nTPM]":"8.7","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.0","Cell RNA - HBF TERT88 [nTPM]":"10.2","Cell RNA - HDLM-2 [nTPM]":"2.7","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"29.8","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"19.5","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"78.4","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"6.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"22.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"10.0","Cell RNA - Karpas-707 [nTPM]":"3.9","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"4.5","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"35.4","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"13.4","Cell RNA - RT4 [nTPM]":"7.8","Cell RNA - SCLC-21H [nTPM]":"6.7","Cell RNA - SH-SY5Y [nTPM]":"15.6","Cell RNA - SiHa [nTPM]":"24.6","Cell RNA - SK-BR-3 [nTPM]":"4.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"17.2","Cell RNA - T-47d [nTPM]":"20.4","Cell RNA - THP-1 [nTPM]":"20.5","Cell RNA - TIME [nTPM]":"19.7","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"5.6","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"4.2","Cell RNA - U-266\/84 [nTPM]":"8.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.3","Cell RNA - U-937 [nTPM]":"6.8","Cell RNA - WM-115 [nTPM]":"19.2","Blood RNA - basophil [nTPM]":"25.3","Blood RNA - classical monocyte [nTPM]":"15.2","Blood RNA - eosinophil [nTPM]":"34.2","Blood RNA - gdT-cell [nTPM]":"11.1","Blood RNA - intermediate monocyte [nTPM]":"16.6","Blood RNA - MAIT T-cell [nTPM]":"24.0","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"8.3","Blood RNA - memory CD8 T-cell [nTPM]":"10.8","Blood RNA - myeloid DC [nTPM]":"8.9","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.0","Blood RNA - naive CD8 T-cell [nTPM]":"7.0","Blood RNA - neutrophil [nTPM]":"11.9","Blood RNA - NK-cell [nTPM]":"16.3","Blood RNA - non-classical monocyte [nTPM]":"13.4","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"5.3","Blood RNA - total PBMC [nTPM]":"11.7","Brain RNA - amygdala [nTPM]":"20.0","Brain RNA - basal ganglia [nTPM]":"23.3","Brain RNA - cerebellum [nTPM]":"22.1","Brain RNA - cerebral cortex [nTPM]":"26.1","Brain RNA - hippocampal formation [nTPM]":"18.5","Brain RNA - hypothalamus [nTPM]":"21.6","Brain RNA - medulla oblongata [nTPM]":"23.0","Brain RNA - midbrain [nTPM]":"22.6","Brain RNA - pons [nTPM]":"23.9","Brain RNA - spinal cord [nTPM]":"22.3","Brain RNA - thalamus [nTPM]":"20.8","Brain RNA - white matter [nTPM]":"30.6","Single Cell Type RNA - Adipocytes [nTPM]":"11.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.0","Single Cell Type RNA - Astrocytes [nTPM]":"26.8","Single Cell Type RNA - B-cells [nTPM]":"8.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"10.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"8.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - dendritic cells [nTPM]":"27.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.8","Single Cell Type RNA - Early spermatids [nTPM]":"51.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.9","Single Cell Type RNA - Endothelial cells [nTPM]":"11.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"13.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.7","Single Cell Type RNA - Fibroblasts [nTPM]":"15.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.8","Single Cell Type RNA - granulocytes [nTPM]":"68.4","Single Cell Type RNA - Granulosa cells [nTPM]":"15.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"6.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.6","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"72.1","Single Cell Type RNA - Langerhans cells [nTPM]":"11.8","Single Cell Type RNA - Late spermatids [nTPM]":"77.9","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"25.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"26.7","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.1","Single Cell Type RNA - Paneth cells [nTPM]":"20.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"9.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"14.9","Single Cell Type RNA - Spermatogonia [nTPM]":"10.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - T-cells [nTPM]":"21.2","Single Cell Type RNA - Theca cells [nTPM]":"12.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.7","Single Cell Type RNA - Urothelial cells [nTPM]":"7.9"},{"Gene":"GALNS","Gene synonym":["GALNAC6S","GAS"],"Ensembl":"ENSG00000141012","Gene description":"Galactosamine (N-acetyl)-6-sulfatase","Uniprot":["P34059"],"Chromosome":"16","Position":"88813734-88856970","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Dwarfism","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"51.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"11.3","granulocytes":"31.3","monocytes":"17.4"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026404","HPA042433","HPA074225"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB026404":null,"HPA042433":"AB_2732499","HPA074225":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.66e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.2","Tissue RNA - adrenal gland [nTPM]":"12.8","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"9.3","Tissue RNA - basal ganglia [nTPM]":"10.0","Tissue RNA - bone marrow [nTPM]":"22.2","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"10.0","Tissue RNA - cerebral cortex [nTPM]":"11.5","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"22.1","Tissue RNA - colon [nTPM]":"10.0","Tissue RNA - duodenum [nTPM]":"10.6","Tissue RNA - endometrium 1 [nTPM]":"7.4","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"8.8","Tissue RNA - fallopian tube [nTPM]":"11.4","Tissue RNA - gallbladder [nTPM]":"9.7","Tissue RNA - heart muscle [nTPM]":"11.0","Tissue RNA - hippocampal formation [nTPM]":"10.6","Tissue RNA - hypothalamus [nTPM]":"12.0","Tissue RNA - kidney [nTPM]":"8.6","Tissue RNA - liver [nTPM]":"8.1","Tissue RNA - lung [nTPM]":"10.4","Tissue RNA - lymph node [nTPM]":"7.4","Tissue RNA - medulla oblongata [nTPM]":"12.6","Tissue RNA - midbrain [nTPM]":"16.4","Tissue RNA - ovary [nTPM]":"6.7","Tissue RNA - pancreas [nTPM]":"5.0","Tissue RNA - parathyroid gland [nTPM]":"8.6","Tissue RNA - pituitary gland [nTPM]":"11.9","Tissue RNA - placenta [nTPM]":"8.6","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"3.3","Tissue RNA - salivary gland [nTPM]":"8.3","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"6.4","Tissue RNA - skin 1 [nTPM]":"8.4","Tissue RNA - small intestine [nTPM]":"10.6","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"10.8","Tissue RNA - spleen [nTPM]":"9.1","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"26.3","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"4.8","Tissue RNA - thyroid gland [nTPM]":"9.1","Tissue RNA - tongue [nTPM]":"3.6","Tissue RNA - tonsil [nTPM]":"5.6","Tissue RNA - urinary bladder [nTPM]":"9.0","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"12.0","Cell RNA - A-431 [nTPM]":"5.7","Cell RNA - A549 [nTPM]":"42.7","Cell RNA - AF22 [nTPM]":"6.2","Cell RNA - AN3-CA [nTPM]":"43.4","Cell RNA - ASC diff [nTPM]":"47.1","Cell RNA - ASC TERT1 [nTPM]":"22.4","Cell RNA - BEWO [nTPM]":"41.9","Cell RNA - BJ [nTPM]":"17.9","Cell RNA - BJ hTERT+ [nTPM]":"27.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.7","Cell RNA - CACO-2 [nTPM]":"22.7","Cell RNA - CAPAN-2 [nTPM]":"36.8","Cell RNA - Daudi [nTPM]":"7.1","Cell RNA - EFO-21 [nTPM]":"37.1","Cell RNA - fHDF\/TERT166 [nTPM]":"29.2","Cell RNA - GAMG [nTPM]":"28.8","Cell RNA - HaCaT [nTPM]":"33.0","Cell RNA - HAP1 [nTPM]":"9.0","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"11.4","Cell RNA - HDLM-2 [nTPM]":"4.7","Cell RNA - HEK 293 [nTPM]":"13.8","Cell RNA - HEL [nTPM]":"4.5","Cell RNA - HeLa [nTPM]":"17.0","Cell RNA - Hep G2 [nTPM]":"13.2","Cell RNA - HHSteC [nTPM]":"31.5","Cell RNA - HL-60 [nTPM]":"3.6","Cell RNA - HMC-1 [nTPM]":"28.5","Cell RNA - HSkMC [nTPM]":"31.4","Cell RNA - hTCEpi [nTPM]":"26.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.4","Cell RNA - hTERT-HME1 [nTPM]":"6.0","Cell RNA - hTERT-RPE1 [nTPM]":"27.0","Cell RNA - HUVEC TERT2 [nTPM]":"16.4","Cell RNA - JURKAT [nTPM]":"7.8","Cell RNA - K-562 [nTPM]":"9.9","Cell RNA - Karpas-707 [nTPM]":"4.1","Cell RNA - LHCN-M2 [nTPM]":"11.3","Cell RNA - MCF7 [nTPM]":"33.3","Cell RNA - MOLT-4 [nTPM]":"9.2","Cell RNA - NB-4 [nTPM]":"15.0","Cell RNA - NTERA-2 [nTPM]":"14.2","Cell RNA - OE19 [nTPM]":"14.3","Cell RNA - PC-3 [nTPM]":"19.6","Cell RNA - REH [nTPM]":"19.6","Cell RNA - RH-30 [nTPM]":"5.4","Cell RNA - RPMI-8226 [nTPM]":"12.1","Cell RNA - RPTEC TERT1 [nTPM]":"11.9","Cell RNA - RT4 [nTPM]":"13.2","Cell RNA - SCLC-21H [nTPM]":"15.8","Cell RNA - SH-SY5Y [nTPM]":"12.2","Cell RNA - SiHa [nTPM]":"42.4","Cell RNA - SK-BR-3 [nTPM]":"4.0","Cell RNA - SK-MEL-30 [nTPM]":"21.9","Cell RNA - SuSa [nTPM]":"14.4","Cell RNA - T-47d [nTPM]":"27.3","Cell RNA - THP-1 [nTPM]":"32.5","Cell RNA - TIME [nTPM]":"31.3","Cell RNA - U-138 MG [nTPM]":"41.8","Cell RNA - U-2 OS [nTPM]":"31.5","Cell RNA - U-2197 [nTPM]":"43.2","Cell RNA - U-251 MG [nTPM]":"10.0","Cell RNA - U-266\/70 [nTPM]":"4.3","Cell RNA - U-266\/84 [nTPM]":"4.5","Cell RNA - U-698 [nTPM]":"12.6","Cell RNA - U-87 MG [nTPM]":"45.2","Cell RNA - U-937 [nTPM]":"29.7","Cell RNA - WM-115 [nTPM]":"25.4","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"17.4","Blood RNA - eosinophil [nTPM]":"31.3","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"12.5","Blood RNA - MAIT T-cell [nTPM]":"3.9","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"11.3","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.1","Blood RNA - neutrophil [nTPM]":"21.7","Blood RNA - NK-cell [nTPM]":"4.0","Blood RNA - non-classical monocyte [nTPM]":"9.6","Blood RNA - plasmacytoid DC [nTPM]":"4.7","Blood RNA - T-reg [nTPM]":"4.6","Blood RNA - total PBMC [nTPM]":"8.5","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"10.0","Brain RNA - cerebellum [nTPM]":"10.0","Brain RNA - cerebral cortex [nTPM]":"11.5","Brain RNA - hippocampal formation [nTPM]":"10.6","Brain RNA - hypothalamus [nTPM]":"12.0","Brain RNA - medulla oblongata [nTPM]":"12.6","Brain RNA - midbrain [nTPM]":"16.4","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"10.8","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"12.0","Single Cell Type RNA - Adipocytes [nTPM]":"4.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"5.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"11.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.9","Single Cell Type RNA - dendritic cells [nTPM]":"8.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.7","Single Cell Type RNA - Early spermatids [nTPM]":"21.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.0","Single Cell Type RNA - Fibroblasts [nTPM]":"13.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"11.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"6.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.7","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.3","Single Cell Type RNA - Late spermatids [nTPM]":"37.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"11.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"18.2","Single Cell Type RNA - Muller glia cells [nTPM]":"8.8","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.6","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"9.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"51.3","Single Cell Type RNA - Spermatogonia [nTPM]":"42.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.9","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"16.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.8"},{"Gene":"GBA","Gene synonym":["GBA1","GLUC"],"Ensembl":"ENSG00000177628","Gene description":"Glucosylceramidase beta","Uniprot":["P04062"],"Chromosome":"1","Position":"155234452-155244699","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Sphingolipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Glycosidase","Glycosyltransferase","Hydrolase","Transferase"],"Disease involvement":["Disease variant","Gaucher disease","Ichthyosis","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"65.2","Syncytiotrophoblasts":"59.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006667","CAB037171","CAB037289"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"470000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037171":"AB_1078958","CAB037289":"AB_1078957","HPA006667":"AB_1078979"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.9","Tissue RNA - adrenal gland [nTPM]":"37.9","Tissue RNA - amygdala [nTPM]":"22.5","Tissue RNA - appendix [nTPM]":"24.8","Tissue RNA - basal ganglia [nTPM]":"24.4","Tissue RNA - bone marrow [nTPM]":"41.7","Tissue RNA - breast [nTPM]":"25.1","Tissue RNA - cerebellum [nTPM]":"25.9","Tissue RNA - cerebral cortex [nTPM]":"24.3","Tissue RNA - cervix [nTPM]":"26.7","Tissue RNA - choroid plexus [nTPM]":"27.4","Tissue RNA - colon [nTPM]":"35.1","Tissue RNA - duodenum [nTPM]":"23.9","Tissue RNA - endometrium 1 [nTPM]":"22.9","Tissue RNA - epididymis [nTPM]":"50.2","Tissue RNA - esophagus [nTPM]":"27.6","Tissue RNA - fallopian tube [nTPM]":"20.5","Tissue RNA - gallbladder [nTPM]":"28.3","Tissue RNA - heart muscle [nTPM]":"19.1","Tissue RNA - hippocampal formation [nTPM]":"26.1","Tissue RNA - hypothalamus [nTPM]":"27.7","Tissue RNA - kidney [nTPM]":"33.6","Tissue RNA - liver [nTPM]":"33.7","Tissue RNA - lung [nTPM]":"28.3","Tissue RNA - lymph node [nTPM]":"19.9","Tissue RNA - medulla oblongata [nTPM]":"27.3","Tissue RNA - midbrain [nTPM]":"28.0","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"33.4","Tissue RNA - parathyroid gland [nTPM]":"103.1","Tissue RNA - pituitary gland [nTPM]":"43.8","Tissue RNA - placenta [nTPM]":"39.2","Tissue RNA - pons [nTPM]":"36.2","Tissue RNA - prostate [nTPM]":"23.3","Tissue RNA - rectum [nTPM]":"39.8","Tissue RNA - retina [nTPM]":"12.4","Tissue RNA - salivary gland [nTPM]":"26.8","Tissue RNA - seminal vesicle [nTPM]":"33.6","Tissue RNA - skeletal muscle [nTPM]":"9.1","Tissue RNA - skin 1 [nTPM]":"33.4","Tissue RNA - small intestine [nTPM]":"22.5","Tissue RNA - smooth muscle [nTPM]":"29.7","Tissue RNA - spinal cord [nTPM]":"25.0","Tissue RNA - spleen [nTPM]":"29.0","Tissue RNA - stomach 1 [nTPM]":"22.7","Tissue RNA - testis [nTPM]":"8.8","Tissue RNA - thalamus [nTPM]":"29.2","Tissue RNA - thymus [nTPM]":"19.7","Tissue RNA - thyroid gland [nTPM]":"37.7","Tissue RNA - tongue [nTPM]":"13.6","Tissue RNA - tonsil [nTPM]":"28.0","Tissue RNA - urinary bladder [nTPM]":"27.1","Tissue RNA - vagina [nTPM]":"21.9","Tissue RNA - white matter [nTPM]":"29.5","Cell RNA - A-431 [nTPM]":"38.0","Cell RNA - A549 [nTPM]":"72.2","Cell RNA - AF22 [nTPM]":"25.1","Cell RNA - AN3-CA [nTPM]":"34.2","Cell RNA - ASC diff [nTPM]":"254.8","Cell RNA - ASC TERT1 [nTPM]":"55.8","Cell RNA - BEWO [nTPM]":"29.3","Cell RNA - BJ [nTPM]":"65.4","Cell RNA - BJ hTERT+ [nTPM]":"230.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"95.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"119.0","Cell RNA - CACO-2 [nTPM]":"43.2","Cell RNA - CAPAN-2 [nTPM]":"135.7","Cell RNA - Daudi [nTPM]":"26.3","Cell RNA - EFO-21 [nTPM]":"70.4","Cell RNA - fHDF\/TERT166 [nTPM]":"153.7","Cell RNA - GAMG [nTPM]":"152.0","Cell RNA - HaCaT [nTPM]":"76.2","Cell RNA - HAP1 [nTPM]":"35.9","Cell RNA - HBEC3-KT [nTPM]":"46.4","Cell RNA - HBF TERT88 [nTPM]":"50.3","Cell RNA - HDLM-2 [nTPM]":"55.5","Cell RNA - HEK 293 [nTPM]":"25.1","Cell RNA - HEL [nTPM]":"21.8","Cell RNA - HeLa [nTPM]":"45.1","Cell RNA - Hep G2 [nTPM]":"23.2","Cell RNA - HHSteC [nTPM]":"73.6","Cell RNA - HL-60 [nTPM]":"25.8","Cell RNA - HMC-1 [nTPM]":"87.0","Cell RNA - HSkMC [nTPM]":"73.4","Cell RNA - hTCEpi [nTPM]":"38.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"199.7","Cell RNA - hTERT-HME1 [nTPM]":"30.2","Cell RNA - hTERT-RPE1 [nTPM]":"100.2","Cell RNA - HUVEC TERT2 [nTPM]":"85.6","Cell RNA - JURKAT [nTPM]":"22.2","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"42.9","Cell RNA - LHCN-M2 [nTPM]":"113.5","Cell RNA - MCF7 [nTPM]":"82.6","Cell RNA - MOLT-4 [nTPM]":"32.5","Cell RNA - NB-4 [nTPM]":"11.9","Cell RNA - NTERA-2 [nTPM]":"16.3","Cell RNA - OE19 [nTPM]":"61.9","Cell RNA - PC-3 [nTPM]":"51.2","Cell RNA - REH [nTPM]":"26.8","Cell RNA - RH-30 [nTPM]":"41.9","Cell RNA - RPMI-8226 [nTPM]":"108.1","Cell RNA - RPTEC TERT1 [nTPM]":"63.9","Cell RNA - RT4 [nTPM]":"29.0","Cell RNA - SCLC-21H [nTPM]":"23.9","Cell RNA - SH-SY5Y [nTPM]":"33.5","Cell RNA - SiHa [nTPM]":"57.4","Cell RNA - SK-BR-3 [nTPM]":"136.4","Cell RNA - SK-MEL-30 [nTPM]":"145.3","Cell RNA - SuSa [nTPM]":"45.6","Cell RNA - T-47d [nTPM]":"102.6","Cell RNA - THP-1 [nTPM]":"63.3","Cell RNA - TIME [nTPM]":"65.7","Cell RNA - U-138 MG [nTPM]":"71.7","Cell RNA - U-2 OS [nTPM]":"31.7","Cell RNA - U-2197 [nTPM]":"91.9","Cell RNA - U-251 MG [nTPM]":"53.7","Cell RNA - U-266\/70 [nTPM]":"86.2","Cell RNA - U-266\/84 [nTPM]":"78.6","Cell RNA - U-698 [nTPM]":"20.4","Cell RNA - U-87 MG [nTPM]":"126.6","Cell RNA - U-937 [nTPM]":"23.4","Cell RNA - WM-115 [nTPM]":"56.4","Blood RNA - basophil [nTPM]":"21.4","Blood RNA - classical monocyte [nTPM]":"36.0","Blood RNA - eosinophil [nTPM]":"15.3","Blood RNA - gdT-cell [nTPM]":"20.8","Blood RNA - intermediate monocyte [nTPM]":"35.8","Blood RNA - MAIT T-cell [nTPM]":"13.2","Blood RNA - memory B-cell [nTPM]":"11.1","Blood RNA - memory CD4 T-cell [nTPM]":"15.7","Blood RNA - memory CD8 T-cell [nTPM]":"13.8","Blood RNA - myeloid DC [nTPM]":"22.4","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"11.0","Blood RNA - naive CD8 T-cell [nTPM]":"11.7","Blood RNA - neutrophil [nTPM]":"28.9","Blood RNA - NK-cell [nTPM]":"11.6","Blood RNA - non-classical monocyte [nTPM]":"37.2","Blood RNA - plasmacytoid DC [nTPM]":"12.5","Blood RNA - T-reg [nTPM]":"23.4","Blood RNA - total PBMC [nTPM]":"23.3","Brain RNA - amygdala [nTPM]":"22.5","Brain RNA - basal ganglia [nTPM]":"24.4","Brain RNA - cerebellum [nTPM]":"25.9","Brain RNA - cerebral cortex [nTPM]":"24.3","Brain RNA - hippocampal formation [nTPM]":"26.1","Brain RNA - hypothalamus [nTPM]":"27.7","Brain RNA - medulla oblongata [nTPM]":"27.3","Brain RNA - midbrain [nTPM]":"28.0","Brain RNA - pons [nTPM]":"36.2","Brain RNA - spinal cord [nTPM]":"25.0","Brain RNA - thalamus [nTPM]":"29.2","Brain RNA - white matter [nTPM]":"29.5","Single Cell Type RNA - Adipocytes [nTPM]":"6.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"8.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.7","Single Cell Type RNA - dendritic cells [nTPM]":"6.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"30.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.6","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.9","Single Cell Type RNA - Fibroblasts [nTPM]":"18.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.9","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"7.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"23.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"65.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"33.3","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"26.8","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"22.8","Single Cell Type RNA - Muller glia cells [nTPM]":"11.7","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.5","Single Cell Type RNA - Paneth cells [nTPM]":"15.8","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"19.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.6","Single Cell Type RNA - Spermatocytes [nTPM]":"22.5","Single Cell Type RNA - Spermatogonia [nTPM]":"12.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.4","Single Cell Type RNA - T-cells [nTPM]":"8.5","Single Cell Type RNA - Theca cells [nTPM]":"6.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.5"},{"Gene":"GLA","Gene synonym":["GALA"],"Ensembl":"ENSG00000102393","Gene description":"Galactosidase alpha","Uniprot":["P06280"],"Chromosome":"X","Position":"101393273-101408012","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"229.9","Plasma cells":"171.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"328.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000237","HPA000966"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000237":"AB_1078968","HPA000966":"AB_1078969"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.62e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.16e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"21.5","Tissue RNA - amygdala [nTPM]":"5.2","Tissue RNA - appendix [nTPM]":"12.7","Tissue RNA - basal ganglia [nTPM]":"5.4","Tissue RNA - bone marrow [nTPM]":"25.1","Tissue RNA - breast [nTPM]":"26.7","Tissue RNA - cerebellum [nTPM]":"6.6","Tissue RNA - cerebral cortex [nTPM]":"6.9","Tissue RNA - cervix [nTPM]":"13.8","Tissue RNA - choroid plexus [nTPM]":"6.2","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"22.4","Tissue RNA - endometrium 1 [nTPM]":"10.9","Tissue RNA - epididymis [nTPM]":"17.5","Tissue RNA - esophagus [nTPM]":"9.3","Tissue RNA - fallopian tube [nTPM]":"15.2","Tissue RNA - gallbladder [nTPM]":"11.8","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"5.6","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"15.6","Tissue RNA - liver [nTPM]":"12.7","Tissue RNA - lung [nTPM]":"17.2","Tissue RNA - lymph node [nTPM]":"13.2","Tissue RNA - medulla oblongata [nTPM]":"7.0","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"9.2","Tissue RNA - pancreas [nTPM]":"6.7","Tissue RNA - parathyroid gland [nTPM]":"31.7","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"22.1","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"7.9","Tissue RNA - rectum [nTPM]":"15.3","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"10.0","Tissue RNA - seminal vesicle [nTPM]":"39.3","Tissue RNA - skeletal muscle [nTPM]":"6.2","Tissue RNA - skin 1 [nTPM]":"9.2","Tissue RNA - small intestine [nTPM]":"13.5","Tissue RNA - smooth muscle [nTPM]":"15.4","Tissue RNA - spinal cord [nTPM]":"6.5","Tissue RNA - spleen [nTPM]":"13.2","Tissue RNA - stomach 1 [nTPM]":"9.3","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"6.9","Tissue RNA - thymus [nTPM]":"12.0","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"15.6","Tissue RNA - urinary bladder [nTPM]":"14.7","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"8.1","Cell RNA - A-431 [nTPM]":"30.5","Cell RNA - A549 [nTPM]":"117.9","Cell RNA - AF22 [nTPM]":"30.8","Cell RNA - AN3-CA [nTPM]":"31.9","Cell RNA - ASC diff [nTPM]":"68.9","Cell RNA - ASC TERT1 [nTPM]":"26.8","Cell RNA - BEWO [nTPM]":"13.8","Cell RNA - BJ [nTPM]":"34.1","Cell RNA - BJ hTERT+ [nTPM]":"51.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"63.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"176.3","Cell RNA - CACO-2 [nTPM]":"64.7","Cell RNA - CAPAN-2 [nTPM]":"45.9","Cell RNA - Daudi [nTPM]":"33.6","Cell RNA - EFO-21 [nTPM]":"70.0","Cell RNA - fHDF\/TERT166 [nTPM]":"35.3","Cell RNA - GAMG [nTPM]":"151.8","Cell RNA - HaCaT [nTPM]":"70.3","Cell RNA - HAP1 [nTPM]":"65.9","Cell RNA - HBEC3-KT [nTPM]":"38.3","Cell RNA - HBF TERT88 [nTPM]":"53.8","Cell RNA - HDLM-2 [nTPM]":"19.3","Cell RNA - HEK 293 [nTPM]":"47.1","Cell RNA - HEL [nTPM]":"18.3","Cell RNA - HeLa [nTPM]":"87.9","Cell RNA - Hep G2 [nTPM]":"78.4","Cell RNA - HHSteC [nTPM]":"19.2","Cell RNA - HL-60 [nTPM]":"26.7","Cell RNA - HMC-1 [nTPM]":"328.1","Cell RNA - HSkMC [nTPM]":"24.3","Cell RNA - hTCEpi [nTPM]":"11.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"72.9","Cell RNA - hTERT-HME1 [nTPM]":"21.6","Cell RNA - hTERT-RPE1 [nTPM]":"17.4","Cell RNA - HUVEC TERT2 [nTPM]":"50.9","Cell RNA - JURKAT [nTPM]":"18.2","Cell RNA - K-562 [nTPM]":"28.6","Cell RNA - Karpas-707 [nTPM]":"71.2","Cell RNA - LHCN-M2 [nTPM]":"60.8","Cell RNA - MCF7 [nTPM]":"52.3","Cell RNA - MOLT-4 [nTPM]":"24.4","Cell RNA - NB-4 [nTPM]":"53.7","Cell RNA - NTERA-2 [nTPM]":"48.2","Cell RNA - OE19 [nTPM]":"72.5","Cell RNA - PC-3 [nTPM]":"46.4","Cell RNA - REH [nTPM]":"18.2","Cell RNA - RH-30 [nTPM]":"39.5","Cell RNA - RPMI-8226 [nTPM]":"81.5","Cell RNA - RPTEC TERT1 [nTPM]":"95.1","Cell RNA - RT4 [nTPM]":"61.9","Cell RNA - SCLC-21H [nTPM]":"11.5","Cell RNA - SH-SY5Y [nTPM]":"19.4","Cell RNA - SiHa [nTPM]":"78.6","Cell RNA - SK-BR-3 [nTPM]":"34.6","Cell RNA - SK-MEL-30 [nTPM]":"30.9","Cell RNA - SuSa [nTPM]":"54.4","Cell RNA - T-47d [nTPM]":"15.2","Cell RNA - THP-1 [nTPM]":"51.2","Cell RNA - TIME [nTPM]":"29.9","Cell RNA - U-138 MG [nTPM]":"20.7","Cell RNA - U-2 OS [nTPM]":"23.8","Cell RNA - U-2197 [nTPM]":"52.6","Cell RNA - U-251 MG [nTPM]":"27.0","Cell RNA - U-266\/70 [nTPM]":"23.0","Cell RNA - U-266\/84 [nTPM]":"26.3","Cell RNA - U-698 [nTPM]":"25.4","Cell RNA - U-87 MG [nTPM]":"36.9","Cell RNA - U-937 [nTPM]":"39.9","Cell RNA - WM-115 [nTPM]":"23.1","Blood RNA - basophil [nTPM]":"22.5","Blood RNA - classical monocyte [nTPM]":"37.3","Blood RNA - eosinophil [nTPM]":"11.9","Blood RNA - gdT-cell [nTPM]":"6.9","Blood RNA - intermediate monocyte [nTPM]":"38.5","Blood RNA - MAIT T-cell [nTPM]":"9.0","Blood RNA - memory B-cell [nTPM]":"8.8","Blood RNA - memory CD4 T-cell [nTPM]":"5.6","Blood RNA - memory CD8 T-cell [nTPM]":"8.8","Blood RNA - myeloid DC [nTPM]":"29.8","Blood RNA - naive B-cell [nTPM]":"9.0","Blood RNA - naive CD4 T-cell [nTPM]":"5.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.9","Blood RNA - neutrophil [nTPM]":"21.6","Blood RNA - NK-cell [nTPM]":"5.6","Blood RNA - non-classical monocyte [nTPM]":"40.6","Blood RNA - plasmacytoid DC [nTPM]":"10.9","Blood RNA - T-reg [nTPM]":"7.3","Blood RNA - total PBMC [nTPM]":"20.4","Brain RNA - amygdala [nTPM]":"5.2","Brain RNA - basal ganglia [nTPM]":"5.4","Brain RNA - cerebellum [nTPM]":"6.6","Brain RNA - cerebral cortex [nTPM]":"6.9","Brain RNA - hippocampal formation [nTPM]":"5.6","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"7.0","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"6.5","Brain RNA - thalamus [nTPM]":"6.9","Brain RNA - white matter [nTPM]":"8.1","Single Cell Type RNA - Adipocytes [nTPM]":"31.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.2","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"65.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"19.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.4","Single Cell Type RNA - dendritic cells [nTPM]":"25.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"22.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"57.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.5","Single Cell Type RNA - Endothelial cells [nTPM]":"30.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.9","Single Cell Type RNA - Erythroid cells [nTPM]":"12.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.3","Single Cell Type RNA - Fibroblasts [nTPM]":"66.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"97.6","Single Cell Type RNA - granulocytes [nTPM]":"31.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"93.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"28.5","Single Cell Type RNA - Langerhans cells [nTPM]":"229.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"115.7","Single Cell Type RNA - Melanocytes [nTPM]":"88.9","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"30.3","Single Cell Type RNA - Muller glia cells [nTPM]":"17.5","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.4","Single Cell Type RNA - Paneth cells [nTPM]":"25.3","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"171.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"70.8","Single Cell Type RNA - Spermatocytes [nTPM]":"6.4","Single Cell Type RNA - Spermatogonia [nTPM]":"5.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"75.5","Single Cell Type RNA - T-cells [nTPM]":"33.2","Single Cell Type RNA - Theca cells [nTPM]":"19.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.2","Single Cell Type RNA - Urothelial cells [nTPM]":"27.9"},{"Gene":"GLB1","Gene synonym":["EBP","ELNR1"],"Ensembl":"ENSG00000170266","Gene description":"Galactosidase beta 1","Uniprot":["P16278"],"Chromosome":"3","Position":"32996609-33097202","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Gangliosidosis","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"857.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008382","HPA040610","HPA069503"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB008382":"AB_590642","HPA040610":"AB_2677039","HPA069503":"AB_2686142"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.0","Tissue RNA - adrenal gland [nTPM]":"36.1","Tissue RNA - amygdala [nTPM]":"12.1","Tissue RNA - appendix [nTPM]":"27.8","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"21.9","Tissue RNA - breast [nTPM]":"20.5","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"14.8","Tissue RNA - cervix [nTPM]":"33.4","Tissue RNA - choroid plexus [nTPM]":"16.0","Tissue RNA - colon [nTPM]":"43.5","Tissue RNA - duodenum [nTPM]":"43.0","Tissue RNA - endometrium 1 [nTPM]":"21.9","Tissue RNA - epididymis [nTPM]":"103.6","Tissue RNA - esophagus [nTPM]":"15.4","Tissue RNA - fallopian tube [nTPM]":"28.2","Tissue RNA - gallbladder [nTPM]":"32.0","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"14.8","Tissue RNA - kidney [nTPM]":"46.0","Tissue RNA - liver [nTPM]":"48.2","Tissue RNA - lung [nTPM]":"42.7","Tissue RNA - lymph node [nTPM]":"25.8","Tissue RNA - medulla oblongata [nTPM]":"14.3","Tissue RNA - midbrain [nTPM]":"12.9","Tissue RNA - ovary [nTPM]":"21.4","Tissue RNA - pancreas [nTPM]":"30.8","Tissue RNA - parathyroid gland [nTPM]":"59.4","Tissue RNA - pituitary gland [nTPM]":"18.5","Tissue RNA - placenta [nTPM]":"53.8","Tissue RNA - pons [nTPM]":"15.4","Tissue RNA - prostate [nTPM]":"23.2","Tissue RNA - rectum [nTPM]":"45.6","Tissue RNA - retina [nTPM]":"14.9","Tissue RNA - salivary gland [nTPM]":"25.3","Tissue RNA - seminal vesicle [nTPM]":"29.3","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"15.8","Tissue RNA - small intestine [nTPM]":"31.0","Tissue RNA - smooth muscle [nTPM]":"30.6","Tissue RNA - spinal cord [nTPM]":"12.4","Tissue RNA - spleen [nTPM]":"24.4","Tissue RNA - stomach 1 [nTPM]":"35.5","Tissue RNA - testis [nTPM]":"13.5","Tissue RNA - thalamus [nTPM]":"13.5","Tissue RNA - thymus [nTPM]":"17.5","Tissue RNA - thyroid gland [nTPM]":"52.8","Tissue RNA - tongue [nTPM]":"10.8","Tissue RNA - tonsil [nTPM]":"23.0","Tissue RNA - urinary bladder [nTPM]":"31.8","Tissue RNA - vagina [nTPM]":"16.2","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"37.4","Cell RNA - A549 [nTPM]":"63.6","Cell RNA - AF22 [nTPM]":"39.8","Cell RNA - AN3-CA [nTPM]":"48.3","Cell RNA - ASC diff [nTPM]":"241.9","Cell RNA - ASC TERT1 [nTPM]":"123.7","Cell RNA - BEWO [nTPM]":"857.2","Cell RNA - BJ [nTPM]":"59.1","Cell RNA - BJ hTERT+ [nTPM]":"157.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"73.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"95.1","Cell RNA - CACO-2 [nTPM]":"91.3","Cell RNA - CAPAN-2 [nTPM]":"86.5","Cell RNA - Daudi [nTPM]":"17.9","Cell RNA - EFO-21 [nTPM]":"50.9","Cell RNA - fHDF\/TERT166 [nTPM]":"120.9","Cell RNA - GAMG [nTPM]":"53.9","Cell RNA - HaCaT [nTPM]":"35.1","Cell RNA - HAP1 [nTPM]":"38.1","Cell RNA - HBEC3-KT [nTPM]":"75.5","Cell RNA - HBF TERT88 [nTPM]":"53.7","Cell RNA - HDLM-2 [nTPM]":"104.9","Cell RNA - HEK 293 [nTPM]":"33.0","Cell RNA - HEL [nTPM]":"69.9","Cell RNA - HeLa [nTPM]":"35.3","Cell RNA - Hep G2 [nTPM]":"47.4","Cell RNA - HHSteC [nTPM]":"124.3","Cell RNA - HL-60 [nTPM]":"50.5","Cell RNA - HMC-1 [nTPM]":"69.9","Cell RNA - HSkMC [nTPM]":"144.9","Cell RNA - hTCEpi [nTPM]":"70.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"67.0","Cell RNA - hTERT-HME1 [nTPM]":"39.2","Cell RNA - hTERT-RPE1 [nTPM]":"144.1","Cell RNA - HUVEC TERT2 [nTPM]":"116.5","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"64.3","Cell RNA - Karpas-707 [nTPM]":"67.0","Cell RNA - LHCN-M2 [nTPM]":"81.8","Cell RNA - MCF7 [nTPM]":"44.6","Cell RNA - MOLT-4 [nTPM]":"29.6","Cell RNA - NB-4 [nTPM]":"31.6","Cell RNA - NTERA-2 [nTPM]":"26.4","Cell RNA - OE19 [nTPM]":"78.0","Cell RNA - PC-3 [nTPM]":"27.0","Cell RNA - REH [nTPM]":"24.7","Cell RNA - RH-30 [nTPM]":"26.4","Cell RNA - RPMI-8226 [nTPM]":"86.6","Cell RNA - RPTEC TERT1 [nTPM]":"78.4","Cell RNA - RT4 [nTPM]":"54.4","Cell RNA - SCLC-21H [nTPM]":"12.0","Cell RNA - SH-SY5Y [nTPM]":"40.3","Cell RNA - SiHa [nTPM]":"75.0","Cell RNA - SK-BR-3 [nTPM]":"120.2","Cell RNA - SK-MEL-30 [nTPM]":"74.4","Cell RNA - SuSa [nTPM]":"69.3","Cell RNA - T-47d [nTPM]":"80.3","Cell RNA - THP-1 [nTPM]":"130.2","Cell RNA - TIME [nTPM]":"67.7","Cell RNA - U-138 MG [nTPM]":"46.8","Cell RNA - U-2 OS [nTPM]":"32.2","Cell RNA - U-2197 [nTPM]":"65.2","Cell RNA - U-251 MG [nTPM]":"50.1","Cell RNA - U-266\/70 [nTPM]":"53.2","Cell RNA - U-266\/84 [nTPM]":"87.9","Cell RNA - U-698 [nTPM]":"5.9","Cell RNA - U-87 MG [nTPM]":"99.6","Cell RNA - U-937 [nTPM]":"71.2","Cell RNA - WM-115 [nTPM]":"36.7","Blood RNA - basophil [nTPM]":"43.9","Blood RNA - classical monocyte [nTPM]":"146.2","Blood RNA - eosinophil [nTPM]":"86.4","Blood RNA - gdT-cell [nTPM]":"29.2","Blood RNA - intermediate monocyte [nTPM]":"125.8","Blood RNA - MAIT T-cell [nTPM]":"40.4","Blood RNA - memory B-cell [nTPM]":"37.9","Blood RNA - memory CD4 T-cell [nTPM]":"34.3","Blood RNA - memory CD8 T-cell [nTPM]":"31.8","Blood RNA - myeloid DC [nTPM]":"166.5","Blood RNA - naive B-cell [nTPM]":"35.6","Blood RNA - naive CD4 T-cell [nTPM]":"17.9","Blood RNA - naive CD8 T-cell [nTPM]":"21.8","Blood RNA - neutrophil [nTPM]":"56.6","Blood RNA - NK-cell [nTPM]":"26.0","Blood RNA - non-classical monocyte [nTPM]":"92.1","Blood RNA - plasmacytoid DC [nTPM]":"35.1","Blood RNA - T-reg [nTPM]":"77.1","Blood RNA - total PBMC [nTPM]":"91.9","Brain RNA - amygdala [nTPM]":"12.1","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"14.8","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"14.8","Brain RNA - medulla oblongata [nTPM]":"14.3","Brain RNA - midbrain [nTPM]":"12.9","Brain RNA - pons [nTPM]":"15.4","Brain RNA - spinal cord [nTPM]":"12.4","Brain RNA - thalamus [nTPM]":"13.5","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"8.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.3","Single Cell Type RNA - Astrocytes [nTPM]":"39.2","Single Cell Type RNA - B-cells [nTPM]":"18.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"60.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"11.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"43.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"100.1","Single Cell Type RNA - dendritic cells [nTPM]":"14.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"53.5","Single Cell Type RNA - Early spermatids [nTPM]":"24.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.0","Single Cell Type RNA - Endothelial cells [nTPM]":"17.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.9","Single Cell Type RNA - Erythroid cells [nTPM]":"20.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"46.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"35.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"55.3","Single Cell Type RNA - Fibroblasts [nTPM]":"29.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.1","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"20.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"39.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"79.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.5","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"43.9","Single Cell Type RNA - Langerhans cells [nTPM]":"13.9","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"41.7","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"64.6","Single Cell Type RNA - Muller glia cells [nTPM]":"16.5","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.1","Single Cell Type RNA - Paneth cells [nTPM]":"43.4","Single Cell Type RNA - Peritubular cells [nTPM]":"21.1","Single Cell Type RNA - Plasma cells [nTPM]":"19.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"6.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.1","Single Cell Type RNA - T-cells [nTPM]":"18.7","Single Cell Type RNA - Theca cells [nTPM]":"51.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.0","Single Cell Type RNA - Urothelial cells [nTPM]":"12.1"},{"Gene":"GM2A","Gene synonym":["SAP-3"],"Ensembl":"ENSG00000196743","Gene description":"GM2 ganglioside activator","Uniprot":["P17900"],"Chromosome":"5","Position":"151212150-151270440","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Gangliosidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"224.7","Hofbauer cells":"100.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"30.9","dendritic cells":"39.6","monocytes":"40.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"207.1","HBEC3-KT":"291.8","hTCEpi":"287.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008063"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008063":"AB_1849842"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.77e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"17.4","Tissue RNA - adrenal gland [nTPM]":"20.5","Tissue RNA - amygdala [nTPM]":"29.3","Tissue RNA - appendix [nTPM]":"30.0","Tissue RNA - basal ganglia [nTPM]":"39.7","Tissue RNA - bone marrow [nTPM]":"20.6","Tissue RNA - breast [nTPM]":"28.0","Tissue RNA - cerebellum [nTPM]":"38.9","Tissue RNA - cerebral cortex [nTPM]":"31.1","Tissue RNA - cervix [nTPM]":"30.8","Tissue RNA - choroid plexus [nTPM]":"17.9","Tissue RNA - colon [nTPM]":"19.7","Tissue RNA - duodenum [nTPM]":"15.8","Tissue RNA - endometrium 1 [nTPM]":"15.1","Tissue RNA - epididymis [nTPM]":"30.8","Tissue RNA - esophagus [nTPM]":"56.2","Tissue RNA - fallopian tube [nTPM]":"15.4","Tissue RNA - gallbladder [nTPM]":"23.4","Tissue RNA - heart muscle [nTPM]":"26.2","Tissue RNA - hippocampal formation [nTPM]":"27.1","Tissue RNA - hypothalamus [nTPM]":"34.3","Tissue RNA - kidney [nTPM]":"11.4","Tissue RNA - liver [nTPM]":"24.8","Tissue RNA - lung [nTPM]":"39.0","Tissue RNA - lymph node [nTPM]":"61.4","Tissue RNA - medulla oblongata [nTPM]":"42.6","Tissue RNA - midbrain [nTPM]":"37.9","Tissue RNA - ovary [nTPM]":"21.3","Tissue RNA - pancreas [nTPM]":"14.9","Tissue RNA - parathyroid gland [nTPM]":"28.3","Tissue RNA - pituitary gland [nTPM]":"6.6","Tissue RNA - placenta [nTPM]":"57.9","Tissue RNA - pons [nTPM]":"44.3","Tissue RNA - prostate [nTPM]":"21.1","Tissue RNA - rectum [nTPM]":"26.3","Tissue RNA - retina [nTPM]":"11.7","Tissue RNA - salivary gland [nTPM]":"17.0","Tissue RNA - seminal vesicle [nTPM]":"17.9","Tissue RNA - skeletal muscle [nTPM]":"7.2","Tissue RNA - skin 1 [nTPM]":"81.8","Tissue RNA - small intestine [nTPM]":"16.3","Tissue RNA - smooth muscle [nTPM]":"20.0","Tissue RNA - spinal cord [nTPM]":"39.0","Tissue RNA - spleen [nTPM]":"36.0","Tissue RNA - stomach 1 [nTPM]":"15.8","Tissue RNA - testis [nTPM]":"11.6","Tissue RNA - thalamus [nTPM]":"36.2","Tissue RNA - thymus [nTPM]":"72.3","Tissue RNA - thyroid gland [nTPM]":"13.0","Tissue RNA - tongue [nTPM]":"10.5","Tissue RNA - tonsil [nTPM]":"77.9","Tissue RNA - urinary bladder [nTPM]":"40.3","Tissue RNA - vagina [nTPM]":"49.5","Tissue RNA - white matter [nTPM]":"46.7","Cell RNA - A-431 [nTPM]":"22.3","Cell RNA - A549 [nTPM]":"14.8","Cell RNA - AF22 [nTPM]":"15.1","Cell RNA - AN3-CA [nTPM]":"71.7","Cell RNA - ASC diff [nTPM]":"98.0","Cell RNA - ASC TERT1 [nTPM]":"48.2","Cell RNA - BEWO [nTPM]":"207.1","Cell RNA - BJ [nTPM]":"35.0","Cell RNA - BJ hTERT+ [nTPM]":"75.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.6","Cell RNA - CACO-2 [nTPM]":"30.3","Cell RNA - CAPAN-2 [nTPM]":"26.1","Cell RNA - Daudi [nTPM]":"71.9","Cell RNA - EFO-21 [nTPM]":"35.1","Cell RNA - fHDF\/TERT166 [nTPM]":"26.9","Cell RNA - GAMG [nTPM]":"51.1","Cell RNA - HaCaT [nTPM]":"60.0","Cell RNA - HAP1 [nTPM]":"16.7","Cell RNA - HBEC3-KT [nTPM]":"291.8","Cell RNA - HBF TERT88 [nTPM]":"27.2","Cell RNA - HDLM-2 [nTPM]":"41.4","Cell RNA - HEK 293 [nTPM]":"10.5","Cell RNA - HEL [nTPM]":"11.7","Cell RNA - HeLa [nTPM]":"16.8","Cell RNA - Hep G2 [nTPM]":"37.9","Cell RNA - HHSteC [nTPM]":"23.7","Cell RNA - HL-60 [nTPM]":"19.1","Cell RNA - HMC-1 [nTPM]":"117.1","Cell RNA - HSkMC [nTPM]":"65.4","Cell RNA - hTCEpi [nTPM]":"287.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.4","Cell RNA - hTERT-HME1 [nTPM]":"16.4","Cell RNA - hTERT-RPE1 [nTPM]":"26.0","Cell RNA - HUVEC TERT2 [nTPM]":"27.6","Cell RNA - JURKAT [nTPM]":"85.1","Cell RNA - K-562 [nTPM]":"11.4","Cell RNA - Karpas-707 [nTPM]":"30.7","Cell RNA - LHCN-M2 [nTPM]":"30.1","Cell RNA - MCF7 [nTPM]":"9.6","Cell RNA - MOLT-4 [nTPM]":"38.4","Cell RNA - NB-4 [nTPM]":"18.0","Cell RNA - NTERA-2 [nTPM]":"10.2","Cell RNA - OE19 [nTPM]":"11.4","Cell RNA - PC-3 [nTPM]":"32.3","Cell RNA - REH [nTPM]":"17.7","Cell RNA - RH-30 [nTPM]":"7.1","Cell RNA - RPMI-8226 [nTPM]":"46.3","Cell RNA - RPTEC TERT1 [nTPM]":"18.4","Cell RNA - RT4 [nTPM]":"43.3","Cell RNA - SCLC-21H [nTPM]":"3.9","Cell RNA - SH-SY5Y [nTPM]":"13.4","Cell RNA - SiHa [nTPM]":"29.1","Cell RNA - SK-BR-3 [nTPM]":"133.0","Cell RNA - SK-MEL-30 [nTPM]":"58.3","Cell RNA - SuSa [nTPM]":"52.0","Cell RNA - T-47d [nTPM]":"30.7","Cell RNA - THP-1 [nTPM]":"22.5","Cell RNA - TIME [nTPM]":"24.6","Cell RNA - U-138 MG [nTPM]":"46.0","Cell RNA - U-2 OS [nTPM]":"17.6","Cell RNA - U-2197 [nTPM]":"38.3","Cell RNA - U-251 MG [nTPM]":"10.6","Cell RNA - U-266\/70 [nTPM]":"75.2","Cell RNA - U-266\/84 [nTPM]":"96.8","Cell RNA - U-698 [nTPM]":"187.0","Cell RNA - U-87 MG [nTPM]":"53.1","Cell RNA - U-937 [nTPM]":"30.1","Cell RNA - WM-115 [nTPM]":"19.4","Blood RNA - basophil [nTPM]":"7.6","Blood RNA - classical monocyte [nTPM]":"40.4","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"13.6","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"30.9","Blood RNA - memory CD4 T-cell [nTPM]":"4.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"39.6","Blood RNA - naive B-cell [nTPM]":"29.8","Blood RNA - naive CD4 T-cell [nTPM]":"6.1","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"8.7","Blood RNA - NK-cell [nTPM]":"4.4","Blood RNA - non-classical monocyte [nTPM]":"3.4","Blood RNA - plasmacytoid DC [nTPM]":"28.0","Blood RNA - T-reg [nTPM]":"5.4","Blood RNA - total PBMC [nTPM]":"18.6","Brain RNA - amygdala [nTPM]":"29.3","Brain RNA - basal ganglia [nTPM]":"39.7","Brain RNA - cerebellum [nTPM]":"38.9","Brain RNA - cerebral cortex [nTPM]":"31.1","Brain RNA - hippocampal formation [nTPM]":"27.1","Brain RNA - hypothalamus [nTPM]":"34.3","Brain RNA - medulla oblongata [nTPM]":"42.6","Brain RNA - midbrain [nTPM]":"37.9","Brain RNA - pons [nTPM]":"44.3","Brain RNA - spinal cord [nTPM]":"39.0","Brain RNA - thalamus [nTPM]":"36.2","Brain RNA - white matter [nTPM]":"46.7","Single Cell Type RNA - Adipocytes [nTPM]":"5.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"25.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Bipolar cells [nTPM]":"5.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"29.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.6","Single Cell Type RNA - dendritic cells [nTPM]":"8.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.8","Single Cell Type RNA - Endothelial cells [nTPM]":"7.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"224.7","Single Cell Type RNA - Fibroblasts [nTPM]":"10.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.7","Single Cell Type RNA - granulocytes [nTPM]":"69.6","Single Cell Type RNA - Granulosa cells [nTPM]":"16.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"24.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"100.8","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"55.7","Single Cell Type RNA - Langerhans cells [nTPM]":"32.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"67.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"52.5","Single Cell Type RNA - Muller glia cells [nTPM]":"8.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.0","Single Cell Type RNA - Paneth cells [nTPM]":"4.7","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"28.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"4.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.5","Single Cell Type RNA - T-cells [nTPM]":"5.6","Single Cell Type RNA - Theca cells [nTPM]":"6.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.7","Single Cell Type RNA - Urothelial cells [nTPM]":"36.5"},{"Gene":"GNE","Gene synonym":["IBM2","Uae1"],"Ensembl":"ENSG00000159921","Gene description":"Glucosamine (UDP-N-acetyl)-2-epimerase\/N-acetylmannosamine kinase","Uniprot":["Q9Y223"],"Chromosome":"9","Position":"36214441-36277042","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Allosteric enzyme","Hydrolase","Kinase","Multifunctional enzyme","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"48.4","liver":"90.5","salivary gland":"55.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"59.3","Hepatocytes":"119.3","Intestinal goblet cells":"88.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPTEC TERT1":"107.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007045","HPA027258"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007045":"AB_1079003","HPA027258":"AB_1849873"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.28e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"9.0","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"8.7","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"15.5","Tissue RNA - breast [nTPM]":"15.8","Tissue RNA - cerebellum [nTPM]":"8.9","Tissue RNA - cerebral cortex [nTPM]":"6.5","Tissue RNA - cervix [nTPM]":"11.3","Tissue RNA - choroid plexus [nTPM]":"7.9","Tissue RNA - colon [nTPM]":"34.0","Tissue RNA - duodenum [nTPM]":"4.3","Tissue RNA - endometrium 1 [nTPM]":"10.3","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"11.6","Tissue RNA - fallopian tube [nTPM]":"9.1","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"5.5","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"10.0","Tissue RNA - liver [nTPM]":"90.5","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"7.3","Tissue RNA - medulla oblongata [nTPM]":"7.7","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"14.8","Tissue RNA - pancreas [nTPM]":"10.2","Tissue RNA - parathyroid gland [nTPM]":"6.1","Tissue RNA - pituitary gland [nTPM]":"4.8","Tissue RNA - placenta [nTPM]":"14.2","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"15.3","Tissue RNA - rectum [nTPM]":"48.4","Tissue RNA - retina [nTPM]":"8.0","Tissue RNA - salivary gland [nTPM]":"55.3","Tissue RNA - seminal vesicle [nTPM]":"7.2","Tissue RNA - skeletal muscle [nTPM]":"7.9","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"7.6","Tissue RNA - smooth muscle [nTPM]":"11.7","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"6.2","Tissue RNA - thyroid gland [nTPM]":"6.9","Tissue RNA - tongue [nTPM]":"15.3","Tissue RNA - tonsil [nTPM]":"9.5","Tissue RNA - urinary bladder [nTPM]":"14.2","Tissue RNA - vagina [nTPM]":"7.5","Tissue RNA - white matter [nTPM]":"10.5","Cell RNA - A-431 [nTPM]":"9.9","Cell RNA - A549 [nTPM]":"44.4","Cell RNA - AF22 [nTPM]":"20.1","Cell RNA - AN3-CA [nTPM]":"17.1","Cell RNA - ASC diff [nTPM]":"22.5","Cell RNA - ASC TERT1 [nTPM]":"22.4","Cell RNA - BEWO [nTPM]":"29.9","Cell RNA - BJ [nTPM]":"13.5","Cell RNA - BJ hTERT+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.1","Cell RNA - CACO-2 [nTPM]":"10.5","Cell RNA - CAPAN-2 [nTPM]":"32.6","Cell RNA - Daudi [nTPM]":"13.5","Cell RNA - EFO-21 [nTPM]":"14.2","Cell RNA - fHDF\/TERT166 [nTPM]":"24.2","Cell RNA - GAMG [nTPM]":"50.5","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"15.3","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"21.8","Cell RNA - HDLM-2 [nTPM]":"25.1","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"11.0","Cell RNA - HeLa [nTPM]":"26.0","Cell RNA - Hep G2 [nTPM]":"15.2","Cell RNA - HHSteC [nTPM]":"15.4","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"31.2","Cell RNA - HSkMC [nTPM]":"14.4","Cell RNA - hTCEpi [nTPM]":"4.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.0","Cell RNA - hTERT-HME1 [nTPM]":"30.6","Cell RNA - hTERT-RPE1 [nTPM]":"14.3","Cell RNA - HUVEC TERT2 [nTPM]":"8.4","Cell RNA - JURKAT [nTPM]":"20.7","Cell RNA - K-562 [nTPM]":"14.4","Cell RNA - Karpas-707 [nTPM]":"27.3","Cell RNA - LHCN-M2 [nTPM]":"19.3","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"19.1","Cell RNA - NB-4 [nTPM]":"6.3","Cell RNA - NTERA-2 [nTPM]":"11.8","Cell RNA - OE19 [nTPM]":"6.7","Cell RNA - PC-3 [nTPM]":"23.7","Cell RNA - REH [nTPM]":"15.5","Cell RNA - RH-30 [nTPM]":"16.3","Cell RNA - RPMI-8226 [nTPM]":"3.8","Cell RNA - RPTEC TERT1 [nTPM]":"107.7","Cell RNA - RT4 [nTPM]":"19.4","Cell RNA - SCLC-21H [nTPM]":"16.7","Cell RNA - SH-SY5Y [nTPM]":"15.2","Cell RNA - SiHa [nTPM]":"13.7","Cell RNA - SK-BR-3 [nTPM]":"5.3","Cell RNA - SK-MEL-30 [nTPM]":"12.6","Cell RNA - SuSa [nTPM]":"7.1","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"12.0","Cell RNA - TIME [nTPM]":"12.2","Cell RNA - U-138 MG [nTPM]":"12.7","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"15.5","Cell RNA - U-251 MG [nTPM]":"12.2","Cell RNA - U-266\/70 [nTPM]":"11.7","Cell RNA - U-266\/84 [nTPM]":"26.0","Cell RNA - U-698 [nTPM]":"7.0","Cell RNA - U-87 MG [nTPM]":"17.0","Cell RNA - U-937 [nTPM]":"9.8","Cell RNA - WM-115 [nTPM]":"18.2","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"8.9","Brain RNA - cerebral cortex [nTPM]":"6.5","Brain RNA - hippocampal formation [nTPM]":"5.5","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"7.7","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"10.5","Single Cell Type RNA - Adipocytes [nTPM]":"9.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.0","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"7.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"8.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"16.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.6","Single Cell Type RNA - dendritic cells [nTPM]":"4.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"59.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.1","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.5","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.5","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.6","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"9.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"119.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.9","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"88.1","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"5.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"6.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.3","Single Cell Type RNA - Paneth cells [nTPM]":"20.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"7.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.8","Single Cell Type RNA - T-cells [nTPM]":"5.7","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.8","Single Cell Type RNA - Urothelial cells [nTPM]":"13.4"},{"Gene":"GNPTAB","Gene synonym":["GNPTA","KIAA1208","MGC4170"],"Ensembl":"ENSG00000111670","Gene description":"N-acetylglucosamine-1-phosphate transferase subunits alpha and beta","Uniprot":["Q3T906"],"Chromosome":"12","Position":"101745499-101830959","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mucolipidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"192.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014558","HPA042343"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA014558":"AB_2732409","HPA042343":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.48e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"18.8","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"22.2","Tissue RNA - bone marrow [nTPM]":"23.9","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"14.4","Tissue RNA - cerebral cortex [nTPM]":"20.0","Tissue RNA - cervix [nTPM]":"17.4","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"29.6","Tissue RNA - duodenum [nTPM]":"14.2","Tissue RNA - endometrium 1 [nTPM]":"11.8","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"8.8","Tissue RNA - gallbladder [nTPM]":"14.8","Tissue RNA - heart muscle [nTPM]":"21.5","Tissue RNA - hippocampal formation [nTPM]":"22.7","Tissue RNA - hypothalamus [nTPM]":"10.8","Tissue RNA - kidney [nTPM]":"14.5","Tissue RNA - liver [nTPM]":"9.4","Tissue RNA - lung [nTPM]":"27.0","Tissue RNA - lymph node [nTPM]":"20.6","Tissue RNA - medulla oblongata [nTPM]":"8.5","Tissue RNA - midbrain [nTPM]":"11.1","Tissue RNA - ovary [nTPM]":"7.2","Tissue RNA - pancreas [nTPM]":"11.3","Tissue RNA - parathyroid gland [nTPM]":"23.0","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"14.8","Tissue RNA - pons [nTPM]":"9.7","Tissue RNA - prostate [nTPM]":"20.1","Tissue RNA - rectum [nTPM]":"30.3","Tissue RNA - retina [nTPM]":"13.0","Tissue RNA - salivary gland [nTPM]":"54.3","Tissue RNA - seminal vesicle [nTPM]":"13.0","Tissue RNA - skeletal muscle [nTPM]":"16.4","Tissue RNA - skin 1 [nTPM]":"25.1","Tissue RNA - small intestine [nTPM]":"16.2","Tissue RNA - smooth muscle [nTPM]":"15.9","Tissue RNA - spinal cord [nTPM]":"8.9","Tissue RNA - spleen [nTPM]":"19.0","Tissue RNA - stomach 1 [nTPM]":"21.3","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"12.4","Tissue RNA - thymus [nTPM]":"34.1","Tissue RNA - thyroid gland [nTPM]":"13.9","Tissue RNA - tongue [nTPM]":"25.9","Tissue RNA - tonsil [nTPM]":"17.8","Tissue RNA - urinary bladder [nTPM]":"19.3","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"18.2","Cell RNA - A549 [nTPM]":"17.5","Cell RNA - AF22 [nTPM]":"6.4","Cell RNA - AN3-CA [nTPM]":"10.9","Cell RNA - ASC diff [nTPM]":"52.3","Cell RNA - ASC TERT1 [nTPM]":"24.8","Cell RNA - BEWO [nTPM]":"19.6","Cell RNA - BJ [nTPM]":"25.4","Cell RNA - BJ hTERT+ [nTPM]":"52.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.2","Cell RNA - CACO-2 [nTPM]":"13.5","Cell RNA - CAPAN-2 [nTPM]":"12.4","Cell RNA - Daudi [nTPM]":"38.1","Cell RNA - EFO-21 [nTPM]":"17.9","Cell RNA - fHDF\/TERT166 [nTPM]":"35.1","Cell RNA - GAMG [nTPM]":"20.1","Cell RNA - HaCaT [nTPM]":"23.2","Cell RNA - HAP1 [nTPM]":"29.8","Cell RNA - HBEC3-KT [nTPM]":"32.8","Cell RNA - HBF TERT88 [nTPM]":"38.4","Cell RNA - HDLM-2 [nTPM]":"18.1","Cell RNA - HEK 293 [nTPM]":"15.6","Cell RNA - HEL [nTPM]":"16.3","Cell RNA - HeLa [nTPM]":"15.4","Cell RNA - Hep G2 [nTPM]":"19.3","Cell RNA - HHSteC [nTPM]":"9.7","Cell RNA - HL-60 [nTPM]":"15.0","Cell RNA - HMC-1 [nTPM]":"31.7","Cell RNA - HSkMC [nTPM]":"19.3","Cell RNA - hTCEpi [nTPM]":"17.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.5","Cell RNA - hTERT-HME1 [nTPM]":"13.8","Cell RNA - hTERT-RPE1 [nTPM]":"61.4","Cell RNA - HUVEC TERT2 [nTPM]":"44.0","Cell RNA - JURKAT [nTPM]":"30.0","Cell RNA - K-562 [nTPM]":"25.9","Cell RNA - Karpas-707 [nTPM]":"11.0","Cell RNA - LHCN-M2 [nTPM]":"23.4","Cell RNA - MCF7 [nTPM]":"27.8","Cell RNA - MOLT-4 [nTPM]":"45.6","Cell RNA - NB-4 [nTPM]":"21.0","Cell RNA - NTERA-2 [nTPM]":"22.0","Cell RNA - OE19 [nTPM]":"22.6","Cell RNA - PC-3 [nTPM]":"12.5","Cell RNA - REH [nTPM]":"10.6","Cell RNA - RH-30 [nTPM]":"32.6","Cell RNA - RPMI-8226 [nTPM]":"51.2","Cell RNA - RPTEC TERT1 [nTPM]":"39.5","Cell RNA - RT4 [nTPM]":"46.8","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"11.2","Cell RNA - SiHa [nTPM]":"42.3","Cell RNA - SK-BR-3 [nTPM]":"29.7","Cell RNA - SK-MEL-30 [nTPM]":"60.7","Cell RNA - SuSa [nTPM]":"23.5","Cell RNA - T-47d [nTPM]":"30.6","Cell RNA - THP-1 [nTPM]":"9.8","Cell RNA - TIME [nTPM]":"43.6","Cell RNA - U-138 MG [nTPM]":"23.1","Cell RNA - U-2 OS [nTPM]":"12.5","Cell RNA - U-2197 [nTPM]":"19.6","Cell RNA - U-251 MG [nTPM]":"14.4","Cell RNA - U-266\/70 [nTPM]":"30.0","Cell RNA - U-266\/84 [nTPM]":"32.9","Cell RNA - U-698 [nTPM]":"21.5","Cell RNA - U-87 MG [nTPM]":"26.4","Cell RNA - U-937 [nTPM]":"21.8","Cell RNA - WM-115 [nTPM]":"14.6","Blood RNA - basophil [nTPM]":"8.6","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"18.8","Blood RNA - intermediate monocyte [nTPM]":"3.6","Blood RNA - MAIT T-cell [nTPM]":"6.2","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.0","Blood RNA - memory CD8 T-cell [nTPM]":"10.3","Blood RNA - myeloid DC [nTPM]":"7.1","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"5.1","Blood RNA - naive CD8 T-cell [nTPM]":"7.9","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"17.0","Blood RNA - non-classical monocyte [nTPM]":"4.6","Blood RNA - plasmacytoid DC [nTPM]":"6.9","Blood RNA - T-reg [nTPM]":"3.3","Blood RNA - total PBMC [nTPM]":"3.7","Brain RNA - amygdala [nTPM]":"18.8","Brain RNA - basal ganglia [nTPM]":"22.2","Brain RNA - cerebellum [nTPM]":"14.4","Brain RNA - cerebral cortex [nTPM]":"20.0","Brain RNA - hippocampal formation [nTPM]":"22.7","Brain RNA - hypothalamus [nTPM]":"10.8","Brain RNA - medulla oblongata [nTPM]":"8.5","Brain RNA - midbrain [nTPM]":"11.1","Brain RNA - pons [nTPM]":"9.7","Brain RNA - spinal cord [nTPM]":"8.9","Brain RNA - thalamus [nTPM]":"12.4","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"25.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"65.0","Single Cell Type RNA - Astrocytes [nTPM]":"35.9","Single Cell Type RNA - B-cells [nTPM]":"42.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"23.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"27.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.7","Single Cell Type RNA - dendritic cells [nTPM]":"107.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"68.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.7","Single Cell Type RNA - Endothelial cells [nTPM]":"21.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"19.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"84.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.0","Single Cell Type RNA - Fibroblasts [nTPM]":"18.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.6","Single Cell Type RNA - granulocytes [nTPM]":"122.8","Single Cell Type RNA - Granulosa cells [nTPM]":"24.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"9.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"46.7","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"83.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.6","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"46.7","Single Cell Type RNA - Langerhans cells [nTPM]":"17.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"17.1","Single Cell Type RNA - Macrophages [nTPM]":"41.2","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"43.5","Single Cell Type RNA - Muller glia cells [nTPM]":"26.9","Single Cell Type RNA - NK-cells [nTPM]":"192.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"135.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.7","Single Cell Type RNA - Paneth cells [nTPM]":"129.3","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"63.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.9","Single Cell Type RNA - Spermatocytes [nTPM]":"12.4","Single Cell Type RNA - Spermatogonia [nTPM]":"33.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - T-cells [nTPM]":"63.4","Single Cell Type RNA - Theca cells [nTPM]":"30.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"49.7","Single Cell Type RNA - Urothelial cells [nTPM]":"46.5"},{"Gene":"GNPTG","Gene synonym":["C16orf27","c316G12.3","CAB56184","GNPTAG"],"Ensembl":"ENSG00000090581","Gene description":"N-acetylglucosamine-1-phosphate transferase subunit gamma","Uniprot":["Q9UJJ9"],"Chromosome":"16","Position":"1351931-1364113","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Mucolipidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"135.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004055"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"560000000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA004055":"AB_1079006"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"34.8","Tissue RNA - adrenal gland [nTPM]":"94.0","Tissue RNA - amygdala [nTPM]":"33.5","Tissue RNA - appendix [nTPM]":"19.3","Tissue RNA - basal ganglia [nTPM]":"41.3","Tissue RNA - bone marrow [nTPM]":"25.0","Tissue RNA - breast [nTPM]":"34.5","Tissue RNA - cerebellum [nTPM]":"37.8","Tissue RNA - cerebral cortex [nTPM]":"43.3","Tissue RNA - cervix [nTPM]":"31.4","Tissue RNA - choroid plexus [nTPM]":"43.2","Tissue RNA - colon [nTPM]":"27.9","Tissue RNA - duodenum [nTPM]":"17.7","Tissue RNA - endometrium 1 [nTPM]":"29.7","Tissue RNA - epididymis [nTPM]":"28.9","Tissue RNA - esophagus [nTPM]":"23.6","Tissue RNA - fallopian tube [nTPM]":"28.5","Tissue RNA - gallbladder [nTPM]":"23.7","Tissue RNA - heart muscle [nTPM]":"28.7","Tissue RNA - hippocampal formation [nTPM]":"32.6","Tissue RNA - hypothalamus [nTPM]":"34.8","Tissue RNA - kidney [nTPM]":"37.1","Tissue RNA - liver [nTPM]":"40.9","Tissue RNA - lung [nTPM]":"28.4","Tissue RNA - lymph node [nTPM]":"27.9","Tissue RNA - medulla oblongata [nTPM]":"38.8","Tissue RNA - midbrain [nTPM]":"35.5","Tissue RNA - ovary [nTPM]":"35.7","Tissue RNA - pancreas [nTPM]":"39.6","Tissue RNA - parathyroid gland [nTPM]":"40.2","Tissue RNA - pituitary gland [nTPM]":"32.9","Tissue RNA - placenta [nTPM]":"20.9","Tissue RNA - pons [nTPM]":"39.3","Tissue RNA - prostate [nTPM]":"29.9","Tissue RNA - rectum [nTPM]":"16.2","Tissue RNA - retina [nTPM]":"15.6","Tissue RNA - salivary gland [nTPM]":"42.9","Tissue RNA - seminal vesicle [nTPM]":"20.7","Tissue RNA - skeletal muscle [nTPM]":"34.6","Tissue RNA - skin 1 [nTPM]":"37.2","Tissue RNA - small intestine [nTPM]":"30.9","Tissue RNA - smooth muscle [nTPM]":"14.9","Tissue RNA - spinal cord [nTPM]":"35.1","Tissue RNA - spleen [nTPM]":"38.3","Tissue RNA - stomach 1 [nTPM]":"34.8","Tissue RNA - testis [nTPM]":"21.4","Tissue RNA - thalamus [nTPM]":"35.7","Tissue RNA - thymus [nTPM]":"13.3","Tissue RNA - thyroid gland [nTPM]":"33.9","Tissue RNA - tongue [nTPM]":"16.9","Tissue RNA - tonsil [nTPM]":"14.4","Tissue RNA - urinary bladder [nTPM]":"28.8","Tissue RNA - vagina [nTPM]":"26.5","Tissue RNA - white matter [nTPM]":"44.5","Cell RNA - A-431 [nTPM]":"13.3","Cell RNA - A549 [nTPM]":"21.2","Cell RNA - AF22 [nTPM]":"15.3","Cell RNA - AN3-CA [nTPM]":"26.9","Cell RNA - ASC diff [nTPM]":"135.2","Cell RNA - ASC TERT1 [nTPM]":"50.3","Cell RNA - BEWO [nTPM]":"20.1","Cell RNA - BJ [nTPM]":"38.3","Cell RNA - BJ hTERT+ [nTPM]":"49.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.4","Cell RNA - CACO-2 [nTPM]":"19.1","Cell RNA - CAPAN-2 [nTPM]":"37.0","Cell RNA - Daudi [nTPM]":"8.4","Cell RNA - EFO-21 [nTPM]":"43.0","Cell RNA - fHDF\/TERT166 [nTPM]":"51.8","Cell RNA - GAMG [nTPM]":"22.5","Cell RNA - HaCaT [nTPM]":"24.0","Cell RNA - HAP1 [nTPM]":"9.2","Cell RNA - HBEC3-KT [nTPM]":"22.4","Cell RNA - HBF TERT88 [nTPM]":"7.6","Cell RNA - HDLM-2 [nTPM]":"27.0","Cell RNA - HEK 293 [nTPM]":"20.2","Cell RNA - HEL [nTPM]":"11.3","Cell RNA - HeLa [nTPM]":"73.9","Cell RNA - Hep G2 [nTPM]":"33.0","Cell RNA - HHSteC [nTPM]":"57.6","Cell RNA - HL-60 [nTPM]":"18.2","Cell RNA - HMC-1 [nTPM]":"43.2","Cell RNA - HSkMC [nTPM]":"67.3","Cell RNA - hTCEpi [nTPM]":"38.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.2","Cell RNA - hTERT-HME1 [nTPM]":"20.3","Cell RNA - hTERT-RPE1 [nTPM]":"41.6","Cell RNA - HUVEC TERT2 [nTPM]":"27.5","Cell RNA - JURKAT [nTPM]":"15.2","Cell RNA - K-562 [nTPM]":"13.7","Cell RNA - Karpas-707 [nTPM]":"48.4","Cell RNA - LHCN-M2 [nTPM]":"24.6","Cell RNA - MCF7 [nTPM]":"30.7","Cell RNA - MOLT-4 [nTPM]":"8.7","Cell RNA - NB-4 [nTPM]":"18.7","Cell RNA - NTERA-2 [nTPM]":"14.4","Cell RNA - OE19 [nTPM]":"33.9","Cell RNA - PC-3 [nTPM]":"11.8","Cell RNA - REH [nTPM]":"30.5","Cell RNA - RH-30 [nTPM]":"12.9","Cell RNA - RPMI-8226 [nTPM]":"38.6","Cell RNA - RPTEC TERT1 [nTPM]":"37.3","Cell RNA - RT4 [nTPM]":"17.1","Cell RNA - SCLC-21H [nTPM]":"12.0","Cell RNA - SH-SY5Y [nTPM]":"15.5","Cell RNA - SiHa [nTPM]":"38.5","Cell RNA - SK-BR-3 [nTPM]":"39.2","Cell RNA - SK-MEL-30 [nTPM]":"28.7","Cell RNA - SuSa [nTPM]":"8.5","Cell RNA - T-47d [nTPM]":"36.9","Cell RNA - THP-1 [nTPM]":"27.3","Cell RNA - TIME [nTPM]":"27.0","Cell RNA - U-138 MG [nTPM]":"29.8","Cell RNA - U-2 OS [nTPM]":"25.5","Cell RNA - U-2197 [nTPM]":"24.6","Cell RNA - U-251 MG [nTPM]":"19.1","Cell RNA - U-266\/70 [nTPM]":"50.6","Cell RNA - U-266\/84 [nTPM]":"40.4","Cell RNA - U-698 [nTPM]":"17.7","Cell RNA - U-87 MG [nTPM]":"24.4","Cell RNA - U-937 [nTPM]":"15.6","Cell RNA - WM-115 [nTPM]":"20.3","Blood RNA - basophil [nTPM]":"70.5","Blood RNA - classical monocyte [nTPM]":"77.0","Blood RNA - eosinophil [nTPM]":"49.5","Blood RNA - gdT-cell [nTPM]":"43.3","Blood RNA - intermediate monocyte [nTPM]":"74.4","Blood RNA - MAIT T-cell [nTPM]":"39.6","Blood RNA - memory B-cell [nTPM]":"32.1","Blood RNA - memory CD4 T-cell [nTPM]":"36.7","Blood RNA - memory CD8 T-cell [nTPM]":"40.8","Blood RNA - myeloid DC [nTPM]":"61.5","Blood RNA - naive B-cell [nTPM]":"31.1","Blood RNA - naive CD4 T-cell [nTPM]":"33.4","Blood RNA - naive CD8 T-cell [nTPM]":"30.8","Blood RNA - neutrophil [nTPM]":"32.0","Blood RNA - NK-cell [nTPM]":"32.6","Blood RNA - non-classical monocyte [nTPM]":"73.9","Blood RNA - plasmacytoid DC [nTPM]":"52.2","Blood RNA - T-reg [nTPM]":"46.9","Blood RNA - total PBMC [nTPM]":"49.7","Brain RNA - amygdala [nTPM]":"33.5","Brain RNA - basal ganglia [nTPM]":"41.3","Brain RNA - cerebellum [nTPM]":"37.8","Brain RNA - cerebral cortex [nTPM]":"43.3","Brain RNA - hippocampal formation [nTPM]":"32.6","Brain RNA - hypothalamus [nTPM]":"34.8","Brain RNA - medulla oblongata [nTPM]":"38.8","Brain RNA - midbrain [nTPM]":"35.5","Brain RNA - pons [nTPM]":"39.3","Brain RNA - spinal cord [nTPM]":"35.1","Brain RNA - thalamus [nTPM]":"35.7","Brain RNA - white matter [nTPM]":"44.5","Single Cell Type RNA - Adipocytes [nTPM]":"39.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"41.7","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"31.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"46.7","Single Cell Type RNA - Bipolar cells [nTPM]":"15.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"43.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.0","Single Cell Type RNA - dendritic cells [nTPM]":"34.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"27.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.8","Single Cell Type RNA - Endothelial cells [nTPM]":"25.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.3","Single Cell Type RNA - Fibroblasts [nTPM]":"49.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"47.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.7","Single Cell Type RNA - granulocytes [nTPM]":"24.6","Single Cell Type RNA - Granulosa cells [nTPM]":"21.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.7","Single Cell Type RNA - Hepatocytes [nTPM]":"35.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"50.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.0","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"43.4","Single Cell Type RNA - Langerhans cells [nTPM]":"41.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"30.1","Single Cell Type RNA - Macrophages [nTPM]":"47.8","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"25.7","Single Cell Type RNA - Muller glia cells [nTPM]":"31.0","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.8","Single Cell Type RNA - Paneth cells [nTPM]":"32.9","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"76.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"41.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.9","Single Cell Type RNA - Spermatocytes [nTPM]":"25.4","Single Cell Type RNA - Spermatogonia [nTPM]":"24.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"48.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.1","Single Cell Type RNA - T-cells [nTPM]":"30.6","Single Cell Type RNA - Theca cells [nTPM]":"20.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.7","Single Cell Type RNA - Urothelial cells [nTPM]":"24.5"},{"Gene":"GNS","Gene synonym":[],"Ensembl":"ENSG00000135677","Gene description":"Glucosamine (N-acetyl)-6-sulfatase","Uniprot":["P15586"],"Chromosome":"12","Position":"64713445-64759431","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"198.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"228.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013695","CAB026011","HPA048508"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"510000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026011":null,"HPA013695":"AB_1849741","HPA048508":"AB_2680423"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.76e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"106.1","Tissue RNA - adrenal gland [nTPM]":"174.7","Tissue RNA - amygdala [nTPM]":"18.0","Tissue RNA - appendix [nTPM]":"56.4","Tissue RNA - basal ganglia [nTPM]":"19.9","Tissue RNA - bone marrow [nTPM]":"25.4","Tissue RNA - breast [nTPM]":"51.9","Tissue RNA - cerebellum [nTPM]":"20.4","Tissue RNA - cerebral cortex [nTPM]":"21.3","Tissue RNA - cervix [nTPM]":"58.9","Tissue RNA - choroid plexus [nTPM]":"80.7","Tissue RNA - colon [nTPM]":"35.3","Tissue RNA - duodenum [nTPM]":"34.6","Tissue RNA - endometrium 1 [nTPM]":"49.5","Tissue RNA - epididymis [nTPM]":"38.5","Tissue RNA - esophagus [nTPM]":"26.2","Tissue RNA - fallopian tube [nTPM]":"43.8","Tissue RNA - gallbladder [nTPM]":"63.7","Tissue RNA - heart muscle [nTPM]":"52.9","Tissue RNA - hippocampal formation [nTPM]":"17.2","Tissue RNA - hypothalamus [nTPM]":"26.4","Tissue RNA - kidney [nTPM]":"132.0","Tissue RNA - liver [nTPM]":"56.2","Tissue RNA - lung [nTPM]":"71.5","Tissue RNA - lymph node [nTPM]":"41.0","Tissue RNA - medulla oblongata [nTPM]":"30.0","Tissue RNA - midbrain [nTPM]":"23.3","Tissue RNA - ovary [nTPM]":"64.3","Tissue RNA - pancreas [nTPM]":"24.1","Tissue RNA - parathyroid gland [nTPM]":"76.8","Tissue RNA - pituitary gland [nTPM]":"23.0","Tissue RNA - placenta [nTPM]":"80.2","Tissue RNA - pons [nTPM]":"25.5","Tissue RNA - prostate [nTPM]":"38.5","Tissue RNA - rectum [nTPM]":"36.9","Tissue RNA - retina [nTPM]":"25.1","Tissue RNA - salivary gland [nTPM]":"32.9","Tissue RNA - seminal vesicle [nTPM]":"47.7","Tissue RNA - skeletal muscle [nTPM]":"30.1","Tissue RNA - skin 1 [nTPM]":"26.3","Tissue RNA - small intestine [nTPM]":"41.4","Tissue RNA - smooth muscle [nTPM]":"69.2","Tissue RNA - spinal cord [nTPM]":"22.5","Tissue RNA - spleen [nTPM]":"51.2","Tissue RNA - stomach 1 [nTPM]":"34.6","Tissue RNA - testis [nTPM]":"31.8","Tissue RNA - thalamus [nTPM]":"27.3","Tissue RNA - thymus [nTPM]":"20.5","Tissue RNA - thyroid gland [nTPM]":"72.8","Tissue RNA - tongue [nTPM]":"29.0","Tissue RNA - tonsil [nTPM]":"26.9","Tissue RNA - urinary bladder [nTPM]":"63.7","Tissue RNA - vagina [nTPM]":"27.6","Tissue RNA - white matter [nTPM]":"31.2","Cell RNA - A-431 [nTPM]":"41.0","Cell RNA - A549 [nTPM]":"61.3","Cell RNA - AF22 [nTPM]":"50.7","Cell RNA - AN3-CA [nTPM]":"81.4","Cell RNA - ASC diff [nTPM]":"240.0","Cell RNA - ASC TERT1 [nTPM]":"145.2","Cell RNA - BEWO [nTPM]":"108.8","Cell RNA - BJ [nTPM]":"92.0","Cell RNA - BJ hTERT+ [nTPM]":"213.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"108.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"117.1","Cell RNA - CACO-2 [nTPM]":"55.9","Cell RNA - CAPAN-2 [nTPM]":"53.3","Cell RNA - Daudi [nTPM]":"17.4","Cell RNA - EFO-21 [nTPM]":"117.0","Cell RNA - fHDF\/TERT166 [nTPM]":"117.8","Cell RNA - GAMG [nTPM]":"133.3","Cell RNA - HaCaT [nTPM]":"33.1","Cell RNA - HAP1 [nTPM]":"49.1","Cell RNA - HBEC3-KT [nTPM]":"52.6","Cell RNA - HBF TERT88 [nTPM]":"119.5","Cell RNA - HDLM-2 [nTPM]":"51.4","Cell RNA - HEK 293 [nTPM]":"36.6","Cell RNA - HEL [nTPM]":"41.4","Cell RNA - HeLa [nTPM]":"45.4","Cell RNA - Hep G2 [nTPM]":"36.4","Cell RNA - HHSteC [nTPM]":"109.3","Cell RNA - HL-60 [nTPM]":"30.6","Cell RNA - HMC-1 [nTPM]":"346.2","Cell RNA - HSkMC [nTPM]":"139.6","Cell RNA - hTCEpi [nTPM]":"62.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"111.5","Cell RNA - hTERT-HME1 [nTPM]":"49.3","Cell RNA - hTERT-RPE1 [nTPM]":"342.0","Cell RNA - HUVEC TERT2 [nTPM]":"200.1","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"28.8","Cell RNA - Karpas-707 [nTPM]":"117.2","Cell RNA - LHCN-M2 [nTPM]":"156.8","Cell RNA - MCF7 [nTPM]":"32.6","Cell RNA - MOLT-4 [nTPM]":"8.1","Cell RNA - NB-4 [nTPM]":"17.9","Cell RNA - NTERA-2 [nTPM]":"19.4","Cell RNA - OE19 [nTPM]":"102.8","Cell RNA - PC-3 [nTPM]":"53.2","Cell RNA - REH [nTPM]":"23.8","Cell RNA - RH-30 [nTPM]":"77.3","Cell RNA - RPMI-8226 [nTPM]":"53.7","Cell RNA - RPTEC TERT1 [nTPM]":"91.5","Cell RNA - RT4 [nTPM]":"116.2","Cell RNA - SCLC-21H [nTPM]":"33.7","Cell RNA - SH-SY5Y [nTPM]":"37.3","Cell RNA - SiHa [nTPM]":"119.6","Cell RNA - SK-BR-3 [nTPM]":"56.6","Cell RNA - SK-MEL-30 [nTPM]":"82.4","Cell RNA - SuSa [nTPM]":"65.8","Cell RNA - T-47d [nTPM]":"102.2","Cell RNA - THP-1 [nTPM]":"40.4","Cell RNA - TIME [nTPM]":"185.1","Cell RNA - U-138 MG [nTPM]":"104.5","Cell RNA - U-2 OS [nTPM]":"54.8","Cell RNA - U-2197 [nTPM]":"101.8","Cell RNA - U-251 MG [nTPM]":"54.4","Cell RNA - U-266\/70 [nTPM]":"112.1","Cell RNA - U-266\/84 [nTPM]":"143.4","Cell RNA - U-698 [nTPM]":"14.9","Cell RNA - U-87 MG [nTPM]":"151.1","Cell RNA - U-937 [nTPM]":"58.4","Cell RNA - WM-115 [nTPM]":"72.1","Blood RNA - basophil [nTPM]":"51.7","Blood RNA - classical monocyte [nTPM]":"136.9","Blood RNA - eosinophil [nTPM]":"27.5","Blood RNA - gdT-cell [nTPM]":"29.3","Blood RNA - intermediate monocyte [nTPM]":"158.4","Blood RNA - MAIT T-cell [nTPM]":"21.9","Blood RNA - memory B-cell [nTPM]":"13.0","Blood RNA - memory CD4 T-cell [nTPM]":"15.9","Blood RNA - memory CD8 T-cell [nTPM]":"22.6","Blood RNA - myeloid DC [nTPM]":"78.2","Blood RNA - naive B-cell [nTPM]":"10.0","Blood RNA - naive CD4 T-cell [nTPM]":"16.4","Blood RNA - naive CD8 T-cell [nTPM]":"16.4","Blood RNA - neutrophil [nTPM]":"56.6","Blood RNA - NK-cell [nTPM]":"18.4","Blood RNA - non-classical monocyte [nTPM]":"228.5","Blood RNA - plasmacytoid DC [nTPM]":"19.3","Blood RNA - T-reg [nTPM]":"13.0","Blood RNA - total PBMC [nTPM]":"101.9","Brain RNA - amygdala [nTPM]":"18.0","Brain RNA - basal ganglia [nTPM]":"19.9","Brain RNA - cerebellum [nTPM]":"20.4","Brain RNA - cerebral cortex [nTPM]":"21.3","Brain RNA - hippocampal formation [nTPM]":"17.2","Brain RNA - hypothalamus [nTPM]":"26.4","Brain RNA - medulla oblongata [nTPM]":"30.0","Brain RNA - midbrain [nTPM]":"23.3","Brain RNA - pons [nTPM]":"25.5","Brain RNA - spinal cord [nTPM]":"22.5","Brain RNA - thalamus [nTPM]":"27.3","Brain RNA - white matter [nTPM]":"31.2","Single Cell Type RNA - Adipocytes [nTPM]":"52.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.7","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"11.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"10.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"59.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"24.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"103.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.3","Single Cell Type RNA - dendritic cells [nTPM]":"18.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"36.2","Single Cell Type RNA - Early spermatids [nTPM]":"24.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.5","Single Cell Type RNA - Endothelial cells [nTPM]":"50.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.9","Single Cell Type RNA - Erythroid cells [nTPM]":"15.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.7","Single Cell Type RNA - Fibroblasts [nTPM]":"40.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.9","Single Cell Type RNA - granulocytes [nTPM]":"48.1","Single Cell Type RNA - Granulosa cells [nTPM]":"36.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"58.5","Single Cell Type RNA - Hepatocytes [nTPM]":"57.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"81.0","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.6","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"198.8","Single Cell Type RNA - Langerhans cells [nTPM]":"46.5","Single Cell Type RNA - Late spermatids [nTPM]":"24.5","Single Cell Type RNA - Leydig cells [nTPM]":"34.8","Single Cell Type RNA - Macrophages [nTPM]":"107.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"79.0","Single Cell Type RNA - Muller glia cells [nTPM]":"20.1","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.0","Single Cell Type RNA - Paneth cells [nTPM]":"15.7","Single Cell Type RNA - Peritubular cells [nTPM]":"37.2","Single Cell Type RNA - Plasma cells [nTPM]":"16.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"60.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"64.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.9","Single Cell Type RNA - Spermatocytes [nTPM]":"11.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.1","Single Cell Type RNA - T-cells [nTPM]":"13.2","Single Cell Type RNA - Theca cells [nTPM]":"30.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.2","Single Cell Type RNA - Urothelial cells [nTPM]":"19.2"},{"Gene":"GRN","Gene synonym":["CLN11","PCDGF","PGRN"],"Ensembl":"ENSG00000030582","Gene description":"Granulin precursor","Uniprot":["P28799"],"Chromosome":"17","Position":"44345246-44353106","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"1420.7","Kupffer cells":"892.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"2057.5","intermediate monocyte":"1122.4","myeloid DC":"1534.2","neutrophil":"851.2","non-classical monocyte":"548.1","plasmacytoid DC":"1331.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"1534.2","granulocytes":"851.2","monocytes":"2057.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008763","CAB019394","HPA028747"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endosomes","Lysosomes"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":138000000,"Blood concentration - Conc. blood MS [pg\/L]":"110000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Lysosomes"],"Subcellular additional location":["Endosomes"],"Antibody RRID":{"CAB019394":null,"HPA008763":"AB_1850339","HPA028747":"AB_10603767"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.78e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"158.9","Tissue RNA - adrenal gland [nTPM]":"123.2","Tissue RNA - amygdala [nTPM]":"61.5","Tissue RNA - appendix [nTPM]":"160.4","Tissue RNA - basal ganglia [nTPM]":"67.2","Tissue RNA - bone marrow [nTPM]":"478.5","Tissue RNA - breast [nTPM]":"120.7","Tissue RNA - cerebellum [nTPM]":"67.7","Tissue RNA - cerebral cortex [nTPM]":"97.3","Tissue RNA - cervix [nTPM]":"156.7","Tissue RNA - choroid plexus [nTPM]":"73.9","Tissue RNA - colon [nTPM]":"189.8","Tissue RNA - duodenum [nTPM]":"130.9","Tissue RNA - endometrium 1 [nTPM]":"108.3","Tissue RNA - epididymis [nTPM]":"134.0","Tissue RNA - esophagus [nTPM]":"534.0","Tissue RNA - fallopian tube [nTPM]":"87.1","Tissue RNA - gallbladder [nTPM]":"157.3","Tissue RNA - heart muscle [nTPM]":"153.0","Tissue RNA - hippocampal formation [nTPM]":"61.0","Tissue RNA - hypothalamus [nTPM]":"69.7","Tissue RNA - kidney [nTPM]":"167.4","Tissue RNA - liver [nTPM]":"118.9","Tissue RNA - lung [nTPM]":"309.5","Tissue RNA - lymph node [nTPM]":"183.2","Tissue RNA - medulla oblongata [nTPM]":"81.0","Tissue RNA - midbrain [nTPM]":"71.5","Tissue RNA - ovary [nTPM]":"73.8","Tissue RNA - pancreas [nTPM]":"108.9","Tissue RNA - parathyroid gland [nTPM]":"87.8","Tissue RNA - pituitary gland [nTPM]":"84.4","Tissue RNA - placenta [nTPM]":"183.2","Tissue RNA - pons [nTPM]":"87.6","Tissue RNA - prostate [nTPM]":"111.7","Tissue RNA - rectum [nTPM]":"110.3","Tissue RNA - retina [nTPM]":"12.5","Tissue RNA - salivary gland [nTPM]":"262.9","Tissue RNA - seminal vesicle [nTPM]":"100.6","Tissue RNA - skeletal muscle [nTPM]":"60.6","Tissue RNA - skin 1 [nTPM]":"189.7","Tissue RNA - small intestine [nTPM]":"179.0","Tissue RNA - smooth muscle [nTPM]":"91.9","Tissue RNA - spinal cord [nTPM]":"71.8","Tissue RNA - spleen [nTPM]":"349.8","Tissue RNA - stomach 1 [nTPM]":"127.9","Tissue RNA - testis [nTPM]":"59.4","Tissue RNA - thalamus [nTPM]":"94.3","Tissue RNA - thymus [nTPM]":"67.8","Tissue RNA - thyroid gland [nTPM]":"127.7","Tissue RNA - tongue [nTPM]":"45.9","Tissue RNA - tonsil [nTPM]":"107.8","Tissue RNA - urinary bladder [nTPM]":"150.0","Tissue RNA - vagina [nTPM]":"198.3","Tissue RNA - white matter [nTPM]":"97.3","Cell RNA - A-431 [nTPM]":"119.3","Cell RNA - A549 [nTPM]":"197.5","Cell RNA - AF22 [nTPM]":"52.7","Cell RNA - AN3-CA [nTPM]":"159.5","Cell RNA - ASC diff [nTPM]":"443.2","Cell RNA - ASC TERT1 [nTPM]":"231.8","Cell RNA - BEWO [nTPM]":"181.2","Cell RNA - BJ [nTPM]":"147.3","Cell RNA - BJ hTERT+ [nTPM]":"447.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"231.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"309.8","Cell RNA - CACO-2 [nTPM]":"86.3","Cell RNA - CAPAN-2 [nTPM]":"294.0","Cell RNA - Daudi [nTPM]":"364.0","Cell RNA - EFO-21 [nTPM]":"299.4","Cell RNA - fHDF\/TERT166 [nTPM]":"217.6","Cell RNA - GAMG [nTPM]":"312.9","Cell RNA - HaCaT [nTPM]":"185.3","Cell RNA - HAP1 [nTPM]":"68.6","Cell RNA - HBEC3-KT [nTPM]":"334.5","Cell RNA - HBF TERT88 [nTPM]":"75.8","Cell RNA - HDLM-2 [nTPM]":"55.8","Cell RNA - HEK 293 [nTPM]":"186.8","Cell RNA - HEL [nTPM]":"38.4","Cell RNA - HeLa [nTPM]":"93.8","Cell RNA - Hep G2 [nTPM]":"175.2","Cell RNA - HHSteC [nTPM]":"245.5","Cell RNA - HL-60 [nTPM]":"61.6","Cell RNA - HMC-1 [nTPM]":"493.6","Cell RNA - HSkMC [nTPM]":"332.4","Cell RNA - hTCEpi [nTPM]":"450.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"188.1","Cell RNA - hTERT-HME1 [nTPM]":"106.0","Cell RNA - hTERT-RPE1 [nTPM]":"391.2","Cell RNA - HUVEC TERT2 [nTPM]":"269.8","Cell RNA - JURKAT [nTPM]":"64.3","Cell RNA - K-562 [nTPM]":"75.1","Cell RNA - Karpas-707 [nTPM]":"51.3","Cell RNA - LHCN-M2 [nTPM]":"148.8","Cell RNA - MCF7 [nTPM]":"183.1","Cell RNA - MOLT-4 [nTPM]":"32.8","Cell RNA - NB-4 [nTPM]":"172.8","Cell RNA - NTERA-2 [nTPM]":"44.3","Cell RNA - OE19 [nTPM]":"110.5","Cell RNA - PC-3 [nTPM]":"334.0","Cell RNA - REH [nTPM]":"97.7","Cell RNA - RH-30 [nTPM]":"180.8","Cell RNA - RPMI-8226 [nTPM]":"433.0","Cell RNA - RPTEC TERT1 [nTPM]":"248.2","Cell RNA - RT4 [nTPM]":"145.9","Cell RNA - SCLC-21H [nTPM]":"54.7","Cell RNA - SH-SY5Y [nTPM]":"74.7","Cell RNA - SiHa [nTPM]":"201.0","Cell RNA - SK-BR-3 [nTPM]":"92.7","Cell RNA - SK-MEL-30 [nTPM]":"360.9","Cell RNA - SuSa [nTPM]":"138.0","Cell RNA - T-47d [nTPM]":"209.4","Cell RNA - THP-1 [nTPM]":"229.0","Cell RNA - TIME [nTPM]":"340.7","Cell RNA - U-138 MG [nTPM]":"437.6","Cell RNA - U-2 OS [nTPM]":"104.6","Cell RNA - U-2197 [nTPM]":"300.5","Cell RNA - U-251 MG [nTPM]":"97.8","Cell RNA - U-266\/70 [nTPM]":"116.3","Cell RNA - U-266\/84 [nTPM]":"313.9","Cell RNA - U-698 [nTPM]":"122.3","Cell RNA - U-87 MG [nTPM]":"268.1","Cell RNA - U-937 [nTPM]":"149.6","Cell RNA - WM-115 [nTPM]":"124.2","Blood RNA - basophil [nTPM]":"215.1","Blood RNA - classical monocyte [nTPM]":"2057.5","Blood RNA - eosinophil [nTPM]":"176.5","Blood RNA - gdT-cell [nTPM]":"35.1","Blood RNA - intermediate monocyte [nTPM]":"1122.4","Blood RNA - MAIT T-cell [nTPM]":"27.8","Blood RNA - memory B-cell [nTPM]":"174.0","Blood RNA - memory CD4 T-cell [nTPM]":"37.1","Blood RNA - memory CD8 T-cell [nTPM]":"31.1","Blood RNA - myeloid DC [nTPM]":"1534.2","Blood RNA - naive B-cell [nTPM]":"112.2","Blood RNA - naive CD4 T-cell [nTPM]":"27.8","Blood RNA - naive CD8 T-cell [nTPM]":"26.5","Blood RNA - neutrophil [nTPM]":"851.2","Blood RNA - NK-cell [nTPM]":"30.6","Blood RNA - non-classical monocyte [nTPM]":"548.1","Blood RNA - plasmacytoid DC [nTPM]":"1331.9","Blood RNA - T-reg [nTPM]":"55.4","Blood RNA - total PBMC [nTPM]":"1613.4","Brain RNA - amygdala [nTPM]":"61.5","Brain RNA - basal ganglia [nTPM]":"67.2","Brain RNA - cerebellum [nTPM]":"67.7","Brain RNA - cerebral cortex [nTPM]":"97.3","Brain RNA - hippocampal formation [nTPM]":"61.0","Brain RNA - hypothalamus [nTPM]":"69.7","Brain RNA - medulla oblongata [nTPM]":"81.0","Brain RNA - midbrain [nTPM]":"71.5","Brain RNA - pons [nTPM]":"87.6","Brain RNA - spinal cord [nTPM]":"71.8","Brain RNA - thalamus [nTPM]":"94.3","Brain RNA - white matter [nTPM]":"97.3","Single Cell Type RNA - Adipocytes [nTPM]":"113.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"83.3","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"82.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"112.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"151.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"574.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"97.9","Single Cell Type RNA - Bipolar cells [nTPM]":"23.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"85.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"69.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"90.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"133.0","Single Cell Type RNA - Club cells [nTPM]":"332.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"218.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"429.1","Single Cell Type RNA - dendritic cells [nTPM]":"195.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"494.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"447.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"103.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"83.8","Single Cell Type RNA - Endothelial cells [nTPM]":"170.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"124.3","Single Cell Type RNA - Erythroid cells [nTPM]":"38.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"307.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"324.1","Single Cell Type RNA - Fibroblasts [nTPM]":"149.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"83.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"372.5","Single Cell Type RNA - granulocytes [nTPM]":"75.5","Single Cell Type RNA - Granulosa cells [nTPM]":"90.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"207.8","Single Cell Type RNA - Hepatocytes [nTPM]":"84.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1420.7","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"214.6","Single Cell Type RNA - Ionocytes [nTPM]":"146.5","Single Cell Type RNA - Kupffer cells [nTPM]":"892.0","Single Cell Type RNA - Langerhans cells [nTPM]":"360.8","Single Cell Type RNA - Late spermatids [nTPM]":"6.8","Single Cell Type RNA - Leydig cells [nTPM]":"60.9","Single Cell Type RNA - Macrophages [nTPM]":"699.2","Single Cell Type RNA - Melanocytes [nTPM]":"208.1","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"501.6","Single Cell Type RNA - Muller glia cells [nTPM]":"58.9","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"285.3","Single Cell Type RNA - Paneth cells [nTPM]":"581.7","Single Cell Type RNA - Peritubular cells [nTPM]":"57.2","Single Cell Type RNA - Plasma cells [nTPM]":"65.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"70.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"312.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"120.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"70.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.8","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"45.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"83.3","Single Cell Type RNA - Spermatocytes [nTPM]":"25.1","Single Cell Type RNA - Spermatogonia [nTPM]":"72.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"255.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"96.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"640.0","Single Cell Type RNA - T-cells [nTPM]":"30.8","Single Cell Type RNA - Theca cells [nTPM]":"89.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"274.5","Single Cell Type RNA - Urothelial cells [nTPM]":"175.6"},{"Gene":"GUSB","Gene synonym":[],"Ensembl":"ENSG00000169919","Gene description":"Glucuronidase beta","Uniprot":["P08236"],"Chromosome":"7","Position":"65960684-65982215","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"213.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036322","HPA036323"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"330000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036322":"AB_10670796","HPA036323":"AB_2675059"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Tissue RNA - adipose tissue [nTPM]":"28.4","Tissue RNA - adrenal gland [nTPM]":"18.2","Tissue RNA - amygdala [nTPM]":"11.0","Tissue RNA - appendix [nTPM]":"22.3","Tissue RNA - basal ganglia [nTPM]":"12.3","Tissue RNA - bone marrow [nTPM]":"84.2","Tissue RNA - breast [nTPM]":"80.9","Tissue RNA - cerebellum [nTPM]":"12.0","Tissue RNA - cerebral cortex [nTPM]":"16.1","Tissue RNA - cervix [nTPM]":"26.7","Tissue RNA - choroid plexus [nTPM]":"14.3","Tissue RNA - colon [nTPM]":"38.2","Tissue RNA - duodenum [nTPM]":"36.1","Tissue RNA - endometrium 1 [nTPM]":"26.2","Tissue RNA - epididymis [nTPM]":"41.8","Tissue RNA - esophagus [nTPM]":"16.4","Tissue RNA - fallopian tube [nTPM]":"24.6","Tissue RNA - gallbladder [nTPM]":"27.6","Tissue RNA - heart muscle [nTPM]":"19.6","Tissue RNA - hippocampal formation [nTPM]":"10.7","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"25.1","Tissue RNA - liver [nTPM]":"104.0","Tissue RNA - lung [nTPM]":"35.7","Tissue RNA - lymph node [nTPM]":"25.6","Tissue RNA - medulla oblongata [nTPM]":"13.2","Tissue RNA - midbrain [nTPM]":"12.2","Tissue RNA - ovary [nTPM]":"19.9","Tissue RNA - pancreas [nTPM]":"33.6","Tissue RNA - parathyroid gland [nTPM]":"30.3","Tissue RNA - pituitary gland [nTPM]":"12.6","Tissue RNA - placenta [nTPM]":"48.2","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"41.9","Tissue RNA - retina [nTPM]":"9.7","Tissue RNA - salivary gland [nTPM]":"32.9","Tissue RNA - seminal vesicle [nTPM]":"21.2","Tissue RNA - skeletal muscle [nTPM]":"10.9","Tissue RNA - skin 1 [nTPM]":"18.8","Tissue RNA - small intestine [nTPM]":"29.8","Tissue RNA - smooth muscle [nTPM]":"19.1","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"34.0","Tissue RNA - stomach 1 [nTPM]":"38.1","Tissue RNA - testis [nTPM]":"19.5","Tissue RNA - thalamus [nTPM]":"13.0","Tissue RNA - thymus [nTPM]":"22.7","Tissue RNA - thyroid gland [nTPM]":"27.7","Tissue RNA - tongue [nTPM]":"14.4","Tissue RNA - tonsil [nTPM]":"24.0","Tissue RNA - urinary bladder [nTPM]":"27.3","Tissue RNA - vagina [nTPM]":"15.4","Tissue RNA - white matter [nTPM]":"13.5","Cell RNA - A-431 [nTPM]":"67.0","Cell RNA - A549 [nTPM]":"26.5","Cell RNA - AF22 [nTPM]":"25.2","Cell RNA - AN3-CA [nTPM]":"56.3","Cell RNA - ASC diff [nTPM]":"80.9","Cell RNA - ASC TERT1 [nTPM]":"49.1","Cell RNA - BEWO [nTPM]":"35.3","Cell RNA - BJ [nTPM]":"21.3","Cell RNA - BJ hTERT+ [nTPM]":"56.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"42.1","Cell RNA - CACO-2 [nTPM]":"37.0","Cell RNA - CAPAN-2 [nTPM]":"67.8","Cell RNA - Daudi [nTPM]":"30.9","Cell RNA - EFO-21 [nTPM]":"32.3","Cell RNA - fHDF\/TERT166 [nTPM]":"26.8","Cell RNA - GAMG [nTPM]":"24.1","Cell RNA - HaCaT [nTPM]":"27.5","Cell RNA - HAP1 [nTPM]":"16.5","Cell RNA - HBEC3-KT [nTPM]":"25.1","Cell RNA - HBF TERT88 [nTPM]":"26.8","Cell RNA - HDLM-2 [nTPM]":"27.3","Cell RNA - HEK 293 [nTPM]":"34.1","Cell RNA - HEL [nTPM]":"41.5","Cell RNA - HeLa [nTPM]":"40.9","Cell RNA - Hep G2 [nTPM]":"27.3","Cell RNA - HHSteC [nTPM]":"39.7","Cell RNA - HL-60 [nTPM]":"89.6","Cell RNA - HMC-1 [nTPM]":"67.1","Cell RNA - HSkMC [nTPM]":"33.4","Cell RNA - hTCEpi [nTPM]":"26.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.3","Cell RNA - hTERT-HME1 [nTPM]":"33.3","Cell RNA - hTERT-RPE1 [nTPM]":"54.5","Cell RNA - HUVEC TERT2 [nTPM]":"39.3","Cell RNA - JURKAT [nTPM]":"18.0","Cell RNA - K-562 [nTPM]":"63.2","Cell RNA - Karpas-707 [nTPM]":"213.5","Cell RNA - LHCN-M2 [nTPM]":"30.5","Cell RNA - MCF7 [nTPM]":"50.3","Cell RNA - MOLT-4 [nTPM]":"34.2","Cell RNA - NB-4 [nTPM]":"92.0","Cell RNA - NTERA-2 [nTPM]":"17.9","Cell RNA - OE19 [nTPM]":"103.0","Cell RNA - PC-3 [nTPM]":"21.0","Cell RNA - REH [nTPM]":"34.4","Cell RNA - RH-30 [nTPM]":"55.9","Cell RNA - RPMI-8226 [nTPM]":"172.4","Cell RNA - RPTEC TERT1 [nTPM]":"29.4","Cell RNA - RT4 [nTPM]":"42.8","Cell RNA - SCLC-21H [nTPM]":"36.2","Cell RNA - SH-SY5Y [nTPM]":"32.7","Cell RNA - SiHa [nTPM]":"55.6","Cell RNA - SK-BR-3 [nTPM]":"129.1","Cell RNA - SK-MEL-30 [nTPM]":"72.3","Cell RNA - SuSa [nTPM]":"29.9","Cell RNA - T-47d [nTPM]":"71.1","Cell RNA - THP-1 [nTPM]":"88.8","Cell RNA - TIME [nTPM]":"28.5","Cell RNA - U-138 MG [nTPM]":"55.3","Cell RNA - U-2 OS [nTPM]":"49.3","Cell RNA - U-2197 [nTPM]":"21.8","Cell RNA - U-251 MG [nTPM]":"53.6","Cell RNA - U-266\/70 [nTPM]":"119.6","Cell RNA - U-266\/84 [nTPM]":"151.9","Cell RNA - U-698 [nTPM]":"50.0","Cell RNA - U-87 MG [nTPM]":"41.0","Cell RNA - U-937 [nTPM]":"116.3","Cell RNA - WM-115 [nTPM]":"68.3","Blood RNA - basophil [nTPM]":"26.0","Blood RNA - classical monocyte [nTPM]":"80.1","Blood RNA - eosinophil [nTPM]":"65.7","Blood RNA - gdT-cell [nTPM]":"32.0","Blood RNA - intermediate monocyte [nTPM]":"103.0","Blood RNA - MAIT T-cell [nTPM]":"28.4","Blood RNA - memory B-cell [nTPM]":"27.7","Blood RNA - memory CD4 T-cell [nTPM]":"24.7","Blood RNA - memory CD8 T-cell [nTPM]":"28.4","Blood RNA - myeloid DC [nTPM]":"80.5","Blood RNA - naive B-cell [nTPM]":"22.6","Blood RNA - naive CD4 T-cell [nTPM]":"16.8","Blood RNA - naive CD8 T-cell [nTPM]":"19.5","Blood RNA - neutrophil [nTPM]":"13.2","Blood RNA - NK-cell [nTPM]":"46.6","Blood RNA - non-classical monocyte [nTPM]":"93.5","Blood RNA - plasmacytoid DC [nTPM]":"34.2","Blood RNA - T-reg [nTPM]":"34.5","Blood RNA - total PBMC [nTPM]":"51.4","Brain RNA - amygdala [nTPM]":"11.0","Brain RNA - basal ganglia [nTPM]":"12.3","Brain RNA - cerebellum [nTPM]":"12.0","Brain RNA - cerebral cortex [nTPM]":"16.1","Brain RNA - hippocampal formation [nTPM]":"10.7","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"13.2","Brain RNA - midbrain [nTPM]":"12.2","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"13.0","Brain RNA - white matter [nTPM]":"13.5","Single Cell Type RNA - Adipocytes [nTPM]":"53.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"58.7","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"33.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"51.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Bipolar cells [nTPM]":"12.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"48.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"81.9","Single Cell Type RNA - dendritic cells [nTPM]":"32.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"52.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"41.1","Single Cell Type RNA - Early spermatids [nTPM]":"59.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.5","Single Cell Type RNA - Endothelial cells [nTPM]":"39.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.0","Single Cell Type RNA - Erythroid cells [nTPM]":"47.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.2","Single Cell Type RNA - Fibroblasts [nTPM]":"49.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"49.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"49.4","Single Cell Type RNA - granulocytes [nTPM]":"36.8","Single Cell Type RNA - Granulosa cells [nTPM]":"38.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.9","Single Cell Type RNA - Hepatocytes [nTPM]":"72.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"126.4","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"51.6","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"88.1","Single Cell Type RNA - Langerhans cells [nTPM]":"33.2","Single Cell Type RNA - Late spermatids [nTPM]":"46.7","Single Cell Type RNA - Leydig cells [nTPM]":"43.2","Single Cell Type RNA - Macrophages [nTPM]":"78.0","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"44.8","Single Cell Type RNA - Muller glia cells [nTPM]":"28.0","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.4","Single Cell Type RNA - Paneth cells [nTPM]":"49.5","Single Cell Type RNA - Peritubular cells [nTPM]":"28.6","Single Cell Type RNA - Plasma cells [nTPM]":"87.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"43.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.0","Single Cell Type RNA - Spermatocytes [nTPM]":"49.6","Single Cell Type RNA - Spermatogonia [nTPM]":"31.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.9","Single Cell Type RNA - T-cells [nTPM]":"32.2","Single Cell Type RNA - Theca cells [nTPM]":"24.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"44.3","Single Cell Type RNA - Urothelial cells [nTPM]":"29.6"},{"Gene":"HEXA","Gene synonym":[],"Ensembl":"ENSG00000213614","Gene description":"Hexosaminidase subunit alpha","Uniprot":["P06865"],"Chromosome":"15","Position":"72340924-72376420","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Gangliosidosis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"234.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018082","HPA054583"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA018082":null,"HPA054583":"AB_2682531"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.63e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"49.8","Tissue RNA - adrenal gland [nTPM]":"56.1","Tissue RNA - amygdala [nTPM]":"18.3","Tissue RNA - appendix [nTPM]":"37.6","Tissue RNA - basal ganglia [nTPM]":"21.1","Tissue RNA - bone marrow [nTPM]":"110.0","Tissue RNA - breast [nTPM]":"58.5","Tissue RNA - cerebellum [nTPM]":"20.4","Tissue RNA - cerebral cortex [nTPM]":"21.6","Tissue RNA - cervix [nTPM]":"73.8","Tissue RNA - choroid plexus [nTPM]":"28.5","Tissue RNA - colon [nTPM]":"55.1","Tissue RNA - duodenum [nTPM]":"49.8","Tissue RNA - endometrium 1 [nTPM]":"42.6","Tissue RNA - epididymis [nTPM]":"164.6","Tissue RNA - esophagus [nTPM]":"24.8","Tissue RNA - fallopian tube [nTPM]":"47.8","Tissue RNA - gallbladder [nTPM]":"76.7","Tissue RNA - heart muscle [nTPM]":"54.3","Tissue RNA - hippocampal formation [nTPM]":"19.9","Tissue RNA - hypothalamus [nTPM]":"20.1","Tissue RNA - kidney [nTPM]":"90.1","Tissue RNA - liver [nTPM]":"79.4","Tissue RNA - lung [nTPM]":"84.2","Tissue RNA - lymph node [nTPM]":"54.2","Tissue RNA - medulla oblongata [nTPM]":"23.0","Tissue RNA - midbrain [nTPM]":"21.3","Tissue RNA - ovary [nTPM]":"39.3","Tissue RNA - pancreas [nTPM]":"30.6","Tissue RNA - parathyroid gland [nTPM]":"54.0","Tissue RNA - pituitary gland [nTPM]":"26.3","Tissue RNA - placenta [nTPM]":"102.0","Tissue RNA - pons [nTPM]":"24.6","Tissue RNA - prostate [nTPM]":"45.3","Tissue RNA - rectum [nTPM]":"67.0","Tissue RNA - retina [nTPM]":"32.1","Tissue RNA - salivary gland [nTPM]":"45.0","Tissue RNA - seminal vesicle [nTPM]":"53.3","Tissue RNA - skeletal muscle [nTPM]":"22.1","Tissue RNA - skin 1 [nTPM]":"21.8","Tissue RNA - small intestine [nTPM]":"41.2","Tissue RNA - smooth muscle [nTPM]":"59.5","Tissue RNA - spinal cord [nTPM]":"21.7","Tissue RNA - spleen [nTPM]":"54.7","Tissue RNA - stomach 1 [nTPM]":"45.1","Tissue RNA - testis [nTPM]":"35.6","Tissue RNA - thalamus [nTPM]":"27.0","Tissue RNA - thymus [nTPM]":"38.1","Tissue RNA - thyroid gland [nTPM]":"76.5","Tissue RNA - tongue [nTPM]":"33.2","Tissue RNA - tonsil [nTPM]":"42.4","Tissue RNA - urinary bladder [nTPM]":"71.6","Tissue RNA - vagina [nTPM]":"19.7","Tissue RNA - white matter [nTPM]":"29.9","Cell RNA - A-431 [nTPM]":"39.8","Cell RNA - A549 [nTPM]":"66.4","Cell RNA - AF22 [nTPM]":"27.8","Cell RNA - AN3-CA [nTPM]":"53.8","Cell RNA - ASC diff [nTPM]":"223.6","Cell RNA - ASC TERT1 [nTPM]":"253.1","Cell RNA - BEWO [nTPM]":"39.7","Cell RNA - BJ [nTPM]":"54.8","Cell RNA - BJ hTERT+ [nTPM]":"274.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"115.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"182.8","Cell RNA - CACO-2 [nTPM]":"34.6","Cell RNA - CAPAN-2 [nTPM]":"282.7","Cell RNA - Daudi [nTPM]":"32.9","Cell RNA - EFO-21 [nTPM]":"50.9","Cell RNA - fHDF\/TERT166 [nTPM]":"110.0","Cell RNA - GAMG [nTPM]":"59.9","Cell RNA - HaCaT [nTPM]":"77.1","Cell RNA - HAP1 [nTPM]":"74.5","Cell RNA - HBEC3-KT [nTPM]":"34.6","Cell RNA - HBF TERT88 [nTPM]":"72.5","Cell RNA - HDLM-2 [nTPM]":"26.5","Cell RNA - HEK 293 [nTPM]":"30.0","Cell RNA - HEL [nTPM]":"41.4","Cell RNA - HeLa [nTPM]":"60.4","Cell RNA - Hep G2 [nTPM]":"60.9","Cell RNA - HHSteC [nTPM]":"172.9","Cell RNA - HL-60 [nTPM]":"99.9","Cell RNA - HMC-1 [nTPM]":"113.1","Cell RNA - HSkMC [nTPM]":"216.7","Cell RNA - hTCEpi [nTPM]":"101.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.4","Cell RNA - hTERT-HME1 [nTPM]":"89.3","Cell RNA - hTERT-RPE1 [nTPM]":"210.3","Cell RNA - HUVEC TERT2 [nTPM]":"107.4","Cell RNA - JURKAT [nTPM]":"48.4","Cell RNA - K-562 [nTPM]":"65.1","Cell RNA - Karpas-707 [nTPM]":"197.6","Cell RNA - LHCN-M2 [nTPM]":"156.0","Cell RNA - MCF7 [nTPM]":"33.9","Cell RNA - MOLT-4 [nTPM]":"21.7","Cell RNA - NB-4 [nTPM]":"50.0","Cell RNA - NTERA-2 [nTPM]":"16.0","Cell RNA - OE19 [nTPM]":"128.9","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"22.3","Cell RNA - RH-30 [nTPM]":"60.6","Cell RNA - RPMI-8226 [nTPM]":"75.3","Cell RNA - RPTEC TERT1 [nTPM]":"129.1","Cell RNA - RT4 [nTPM]":"61.6","Cell RNA - SCLC-21H [nTPM]":"23.8","Cell RNA - SH-SY5Y [nTPM]":"26.4","Cell RNA - SiHa [nTPM]":"136.5","Cell RNA - SK-BR-3 [nTPM]":"126.6","Cell RNA - SK-MEL-30 [nTPM]":"307.3","Cell RNA - SuSa [nTPM]":"56.1","Cell RNA - T-47d [nTPM]":"23.4","Cell RNA - THP-1 [nTPM]":"123.9","Cell RNA - TIME [nTPM]":"54.1","Cell RNA - U-138 MG [nTPM]":"171.9","Cell RNA - U-2 OS [nTPM]":"70.7","Cell RNA - U-2197 [nTPM]":"160.1","Cell RNA - U-251 MG [nTPM]":"59.3","Cell RNA - U-266\/70 [nTPM]":"104.7","Cell RNA - U-266\/84 [nTPM]":"151.8","Cell RNA - U-698 [nTPM]":"33.4","Cell RNA - U-87 MG [nTPM]":"62.1","Cell RNA - U-937 [nTPM]":"130.4","Cell RNA - WM-115 [nTPM]":"85.3","Blood RNA - basophil [nTPM]":"24.2","Blood RNA - classical monocyte [nTPM]":"84.6","Blood RNA - eosinophil [nTPM]":"60.1","Blood RNA - gdT-cell [nTPM]":"43.8","Blood RNA - intermediate monocyte [nTPM]":"35.7","Blood RNA - MAIT T-cell [nTPM]":"38.7","Blood RNA - memory B-cell [nTPM]":"41.1","Blood RNA - memory CD4 T-cell [nTPM]":"28.8","Blood RNA - memory CD8 T-cell [nTPM]":"38.9","Blood RNA - myeloid DC [nTPM]":"98.0","Blood RNA - naive B-cell [nTPM]":"38.0","Blood RNA - naive CD4 T-cell [nTPM]":"22.5","Blood RNA - naive CD8 T-cell [nTPM]":"33.2","Blood RNA - neutrophil [nTPM]":"8.1","Blood RNA - NK-cell [nTPM]":"51.3","Blood RNA - non-classical monocyte [nTPM]":"13.3","Blood RNA - plasmacytoid DC [nTPM]":"37.3","Blood RNA - T-reg [nTPM]":"28.2","Blood RNA - total PBMC [nTPM]":"63.0","Brain RNA - amygdala [nTPM]":"18.3","Brain RNA - basal ganglia [nTPM]":"21.1","Brain RNA - cerebellum [nTPM]":"20.4","Brain RNA - cerebral cortex [nTPM]":"21.6","Brain RNA - hippocampal formation [nTPM]":"19.9","Brain RNA - hypothalamus [nTPM]":"20.1","Brain RNA - medulla oblongata [nTPM]":"23.0","Brain RNA - midbrain [nTPM]":"21.3","Brain RNA - pons [nTPM]":"24.6","Brain RNA - spinal cord [nTPM]":"21.7","Brain RNA - thalamus [nTPM]":"27.0","Brain RNA - white matter [nTPM]":"29.9","Single Cell Type RNA - Adipocytes [nTPM]":"68.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"62.4","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"46.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"33.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"94.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"42.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"68.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"66.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"106.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"150.2","Single Cell Type RNA - dendritic cells [nTPM]":"54.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"88.3","Single Cell Type RNA - Early spermatids [nTPM]":"20.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.2","Single Cell Type RNA - Endothelial cells [nTPM]":"50.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"47.2","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"68.0","Single Cell Type RNA - Fibroblasts [nTPM]":"78.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.6","Single Cell Type RNA - granulocytes [nTPM]":"29.9","Single Cell Type RNA - Granulosa cells [nTPM]":"49.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.5","Single Cell Type RNA - Hepatocytes [nTPM]":"42.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"234.3","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"46.3","Single Cell Type RNA - Ionocytes [nTPM]":"81.4","Single Cell Type RNA - Kupffer cells [nTPM]":"92.8","Single Cell Type RNA - Langerhans cells [nTPM]":"75.0","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"74.3","Single Cell Type RNA - Macrophages [nTPM]":"118.1","Single Cell Type RNA - Melanocytes [nTPM]":"94.3","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"60.3","Single Cell Type RNA - Muller glia cells [nTPM]":"38.4","Single Cell Type RNA - NK-cells [nTPM]":"82.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"39.1","Single Cell Type RNA - Paneth cells [nTPM]":"74.6","Single Cell Type RNA - Peritubular cells [nTPM]":"44.8","Single Cell Type RNA - Plasma cells [nTPM]":"37.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"68.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"66.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"56.9","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.7","Single Cell Type RNA - Spermatocytes [nTPM]":"24.3","Single Cell Type RNA - Spermatogonia [nTPM]":"32.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"157.6","Single Cell Type RNA - T-cells [nTPM]":"36.7","Single Cell Type RNA - Theca cells [nTPM]":"45.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"50.6","Single Cell Type RNA - Urothelial cells [nTPM]":"27.5"},{"Gene":"HEXB","Gene synonym":[],"Ensembl":"ENSG00000049860","Gene description":"Hexosaminidase subunit beta","Uniprot":["P07686"],"Chromosome":"5","Position":"74640023-74722647","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Gangliosidosis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"466.5","Hofbauer cells":"340.2","Syncytiotrophoblasts":"493.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"746.0","GAMG":"646.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055409","HPA056010"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"40000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055409":"AB_2682808","HPA056010":"AB_2683008"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.36e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Tissue RNA - adipose tissue [nTPM]":"92.2","Tissue RNA - adrenal gland [nTPM]":"72.0","Tissue RNA - amygdala [nTPM]":"22.1","Tissue RNA - appendix [nTPM]":"59.7","Tissue RNA - basal ganglia [nTPM]":"25.3","Tissue RNA - bone marrow [nTPM]":"59.9","Tissue RNA - breast [nTPM]":"83.0","Tissue RNA - cerebellum [nTPM]":"22.3","Tissue RNA - cerebral cortex [nTPM]":"32.5","Tissue RNA - cervix [nTPM]":"97.6","Tissue RNA - choroid plexus [nTPM]":"39.4","Tissue RNA - colon [nTPM]":"105.0","Tissue RNA - duodenum [nTPM]":"99.0","Tissue RNA - endometrium 1 [nTPM]":"71.5","Tissue RNA - epididymis [nTPM]":"321.4","Tissue RNA - esophagus [nTPM]":"38.5","Tissue RNA - fallopian tube [nTPM]":"66.7","Tissue RNA - gallbladder [nTPM]":"99.0","Tissue RNA - heart muscle [nTPM]":"84.3","Tissue RNA - hippocampal formation [nTPM]":"23.1","Tissue RNA - hypothalamus [nTPM]":"26.2","Tissue RNA - kidney [nTPM]":"81.6","Tissue RNA - liver [nTPM]":"137.5","Tissue RNA - lung [nTPM]":"111.3","Tissue RNA - lymph node [nTPM]":"47.0","Tissue RNA - medulla oblongata [nTPM]":"23.8","Tissue RNA - midbrain [nTPM]":"22.9","Tissue RNA - ovary [nTPM]":"62.4","Tissue RNA - pancreas [nTPM]":"103.6","Tissue RNA - parathyroid gland [nTPM]":"94.2","Tissue RNA - pituitary gland [nTPM]":"46.6","Tissue RNA - placenta [nTPM]":"319.4","Tissue RNA - pons [nTPM]":"24.7","Tissue RNA - prostate [nTPM]":"98.7","Tissue RNA - rectum [nTPM]":"116.9","Tissue RNA - retina [nTPM]":"33.6","Tissue RNA - salivary gland [nTPM]":"123.4","Tissue RNA - seminal vesicle [nTPM]":"54.0","Tissue RNA - skeletal muscle [nTPM]":"43.3","Tissue RNA - skin 1 [nTPM]":"54.3","Tissue RNA - small intestine [nTPM]":"75.4","Tissue RNA - smooth muscle [nTPM]":"76.1","Tissue RNA - spinal cord [nTPM]":"23.2","Tissue RNA - spleen [nTPM]":"64.7","Tissue RNA - stomach 1 [nTPM]":"88.4","Tissue RNA - testis [nTPM]":"19.6","Tissue RNA - thalamus [nTPM]":"28.2","Tissue RNA - thymus [nTPM]":"29.1","Tissue RNA - thyroid gland [nTPM]":"89.6","Tissue RNA - tongue [nTPM]":"38.4","Tissue RNA - tonsil [nTPM]":"40.4","Tissue RNA - urinary bladder [nTPM]":"94.6","Tissue RNA - vagina [nTPM]":"64.1","Tissue RNA - white matter [nTPM]":"30.4","Cell RNA - A-431 [nTPM]":"147.3","Cell RNA - A549 [nTPM]":"111.0","Cell RNA - AF22 [nTPM]":"39.4","Cell RNA - AN3-CA [nTPM]":"131.8","Cell RNA - ASC diff [nTPM]":"746.0","Cell RNA - ASC TERT1 [nTPM]":"232.3","Cell RNA - BEWO [nTPM]":"122.3","Cell RNA - BJ [nTPM]":"173.5","Cell RNA - BJ hTERT+ [nTPM]":"590.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"175.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"375.2","Cell RNA - CACO-2 [nTPM]":"130.6","Cell RNA - CAPAN-2 [nTPM]":"194.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"133.0","Cell RNA - fHDF\/TERT166 [nTPM]":"152.2","Cell RNA - GAMG [nTPM]":"646.3","Cell RNA - HaCaT [nTPM]":"115.2","Cell RNA - HAP1 [nTPM]":"43.2","Cell RNA - HBEC3-KT [nTPM]":"185.2","Cell RNA - HBF TERT88 [nTPM]":"228.7","Cell RNA - HDLM-2 [nTPM]":"79.2","Cell RNA - HEK 293 [nTPM]":"72.6","Cell RNA - HEL [nTPM]":"19.1","Cell RNA - HeLa [nTPM]":"101.4","Cell RNA - Hep G2 [nTPM]":"101.5","Cell RNA - HHSteC [nTPM]":"216.5","Cell RNA - HL-60 [nTPM]":"16.2","Cell RNA - HMC-1 [nTPM]":"152.3","Cell RNA - HSkMC [nTPM]":"206.7","Cell RNA - hTCEpi [nTPM]":"108.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"180.7","Cell RNA - hTERT-HME1 [nTPM]":"121.3","Cell RNA - hTERT-RPE1 [nTPM]":"275.9","Cell RNA - HUVEC TERT2 [nTPM]":"204.5","Cell RNA - JURKAT [nTPM]":"47.3","Cell RNA - K-562 [nTPM]":"54.3","Cell RNA - Karpas-707 [nTPM]":"236.9","Cell RNA - LHCN-M2 [nTPM]":"194.9","Cell RNA - MCF7 [nTPM]":"145.7","Cell RNA - MOLT-4 [nTPM]":"19.8","Cell RNA - NB-4 [nTPM]":"36.6","Cell RNA - NTERA-2 [nTPM]":"36.8","Cell RNA - OE19 [nTPM]":"142.7","Cell RNA - PC-3 [nTPM]":"47.8","Cell RNA - REH [nTPM]":"43.9","Cell RNA - RH-30 [nTPM]":"56.2","Cell RNA - RPMI-8226 [nTPM]":"191.8","Cell RNA - RPTEC TERT1 [nTPM]":"119.8","Cell RNA - RT4 [nTPM]":"130.4","Cell RNA - SCLC-21H [nTPM]":"24.5","Cell RNA - SH-SY5Y [nTPM]":"30.4","Cell RNA - SiHa [nTPM]":"134.2","Cell RNA - SK-BR-3 [nTPM]":"92.6","Cell RNA - SK-MEL-30 [nTPM]":"180.0","Cell RNA - SuSa [nTPM]":"68.8","Cell RNA - T-47d [nTPM]":"99.1","Cell RNA - THP-1 [nTPM]":"108.6","Cell RNA - TIME [nTPM]":"118.5","Cell RNA - U-138 MG [nTPM]":"112.1","Cell RNA - U-2 OS [nTPM]":"26.6","Cell RNA - U-2197 [nTPM]":"207.8","Cell RNA - U-251 MG [nTPM]":"165.6","Cell RNA - U-266\/70 [nTPM]":"102.6","Cell RNA - U-266\/84 [nTPM]":"191.3","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"257.9","Cell RNA - U-937 [nTPM]":"143.6","Cell RNA - WM-115 [nTPM]":"209.8","Blood RNA - basophil [nTPM]":"86.2","Blood RNA - classical monocyte [nTPM]":"343.2","Blood RNA - eosinophil [nTPM]":"99.1","Blood RNA - gdT-cell [nTPM]":"69.3","Blood RNA - intermediate monocyte [nTPM]":"129.9","Blood RNA - MAIT T-cell [nTPM]":"80.7","Blood RNA - memory B-cell [nTPM]":"45.2","Blood RNA - memory CD4 T-cell [nTPM]":"56.1","Blood RNA - memory CD8 T-cell [nTPM]":"64.0","Blood RNA - myeloid DC [nTPM]":"310.8","Blood RNA - naive B-cell [nTPM]":"28.1","Blood RNA - naive CD4 T-cell [nTPM]":"52.6","Blood RNA - naive CD8 T-cell [nTPM]":"51.3","Blood RNA - neutrophil [nTPM]":"125.2","Blood RNA - NK-cell [nTPM]":"42.4","Blood RNA - non-classical monocyte [nTPM]":"82.5","Blood RNA - plasmacytoid DC [nTPM]":"93.4","Blood RNA - T-reg [nTPM]":"73.2","Blood RNA - total PBMC [nTPM]":"269.0","Brain RNA - amygdala [nTPM]":"22.1","Brain RNA - basal ganglia [nTPM]":"25.3","Brain RNA - cerebellum [nTPM]":"22.3","Brain RNA - cerebral cortex [nTPM]":"32.5","Brain RNA - hippocampal formation [nTPM]":"23.1","Brain RNA - hypothalamus [nTPM]":"26.2","Brain RNA - medulla oblongata [nTPM]":"23.8","Brain RNA - midbrain [nTPM]":"22.9","Brain RNA - pons [nTPM]":"24.7","Brain RNA - spinal cord [nTPM]":"23.2","Brain RNA - thalamus [nTPM]":"28.2","Brain RNA - white matter [nTPM]":"30.4","Single Cell Type RNA - Adipocytes [nTPM]":"49.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"31.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"82.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"103.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"10.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"82.9","Single Cell Type RNA - Club cells [nTPM]":"63.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"466.5","Single Cell Type RNA - dendritic cells [nTPM]":"32.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"68.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"151.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.4","Single Cell Type RNA - Endothelial cells [nTPM]":"56.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.8","Single Cell Type RNA - Erythroid cells [nTPM]":"23.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"125.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"175.4","Single Cell Type RNA - Fibroblasts [nTPM]":"107.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.9","Single Cell Type RNA - granulocytes [nTPM]":"69.8","Single Cell Type RNA - Granulosa cells [nTPM]":"19.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"74.3","Single Cell Type RNA - Hepatocytes [nTPM]":"70.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"340.2","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"56.7","Single Cell Type RNA - Ionocytes [nTPM]":"107.8","Single Cell Type RNA - Kupffer cells [nTPM]":"127.3","Single Cell Type RNA - Langerhans cells [nTPM]":"134.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"85.1","Single Cell Type RNA - Macrophages [nTPM]":"168.8","Single Cell Type RNA - Melanocytes [nTPM]":"72.9","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"114.2","Single Cell Type RNA - Muller glia cells [nTPM]":"35.4","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"65.8","Single Cell Type RNA - Paneth cells [nTPM]":"54.8","Single Cell Type RNA - Peritubular cells [nTPM]":"72.2","Single Cell Type RNA - Plasma cells [nTPM]":"71.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"74.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"99.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"79.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.3","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"493.6","Single Cell Type RNA - T-cells [nTPM]":"35.3","Single Cell Type RNA - Theca cells [nTPM]":"31.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"81.8","Single Cell Type RNA - Urothelial cells [nTPM]":"71.0"},{"Gene":"HGSNAT","Gene synonym":["FLJ32731","HGNAT","TMEM76"],"Ensembl":"ENSG00000165102","Gene description":"Heparan-alpha-glucosaminide N-acetyltransferase","Uniprot":["Q68CP4"],"Chromosome":"8","Position":"43140464-43202855","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029578"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029578":"AB_10602423"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.46e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.33e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.3","Tissue RNA - adrenal gland [nTPM]":"20.0","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"17.5","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"21.7","Tissue RNA - breast [nTPM]":"27.8","Tissue RNA - cerebellum [nTPM]":"10.6","Tissue RNA - cerebral cortex [nTPM]":"13.5","Tissue RNA - cervix [nTPM]":"35.0","Tissue RNA - choroid plexus [nTPM]":"13.8","Tissue RNA - colon [nTPM]":"25.4","Tissue RNA - duodenum [nTPM]":"18.4","Tissue RNA - endometrium 1 [nTPM]":"30.1","Tissue RNA - epididymis [nTPM]":"30.6","Tissue RNA - esophagus [nTPM]":"24.0","Tissue RNA - fallopian tube [nTPM]":"29.0","Tissue RNA - gallbladder [nTPM]":"25.9","Tissue RNA - heart muscle [nTPM]":"23.3","Tissue RNA - hippocampal formation [nTPM]":"13.3","Tissue RNA - hypothalamus [nTPM]":"17.6","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"26.6","Tissue RNA - lung [nTPM]":"24.5","Tissue RNA - lymph node [nTPM]":"11.7","Tissue RNA - medulla oblongata [nTPM]":"13.3","Tissue RNA - midbrain [nTPM]":"12.0","Tissue RNA - ovary [nTPM]":"35.9","Tissue RNA - pancreas [nTPM]":"29.9","Tissue RNA - parathyroid gland [nTPM]":"22.7","Tissue RNA - pituitary gland [nTPM]":"30.7","Tissue RNA - placenta [nTPM]":"28.4","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"26.9","Tissue RNA - rectum [nTPM]":"17.2","Tissue RNA - retina [nTPM]":"12.5","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"23.3","Tissue RNA - skeletal muscle [nTPM]":"14.4","Tissue RNA - skin 1 [nTPM]":"35.4","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"25.1","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"17.6","Tissue RNA - stomach 1 [nTPM]":"23.2","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"15.8","Tissue RNA - thymus [nTPM]":"11.3","Tissue RNA - thyroid gland [nTPM]":"26.9","Tissue RNA - tongue [nTPM]":"17.6","Tissue RNA - tonsil [nTPM]":"15.7","Tissue RNA - urinary bladder [nTPM]":"25.2","Tissue RNA - vagina [nTPM]":"28.7","Tissue RNA - white matter [nTPM]":"13.0","Cell RNA - A-431 [nTPM]":"27.4","Cell RNA - A549 [nTPM]":"36.0","Cell RNA - AF22 [nTPM]":"8.9","Cell RNA - AN3-CA [nTPM]":"18.0","Cell RNA - ASC diff [nTPM]":"71.7","Cell RNA - ASC TERT1 [nTPM]":"53.8","Cell RNA - BEWO [nTPM]":"13.3","Cell RNA - BJ [nTPM]":"30.5","Cell RNA - BJ hTERT+ [nTPM]":"36.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.3","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"39.2","Cell RNA - Daudi [nTPM]":"14.8","Cell RNA - EFO-21 [nTPM]":"20.5","Cell RNA - fHDF\/TERT166 [nTPM]":"42.9","Cell RNA - GAMG [nTPM]":"15.2","Cell RNA - HaCaT [nTPM]":"15.5","Cell RNA - HAP1 [nTPM]":"4.0","Cell RNA - HBEC3-KT [nTPM]":"18.5","Cell RNA - HBF TERT88 [nTPM]":"12.7","Cell RNA - HDLM-2 [nTPM]":"6.4","Cell RNA - HEK 293 [nTPM]":"6.9","Cell RNA - HEL [nTPM]":"16.3","Cell RNA - HeLa [nTPM]":"22.2","Cell RNA - Hep G2 [nTPM]":"8.1","Cell RNA - HHSteC [nTPM]":"23.0","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"36.2","Cell RNA - hTCEpi [nTPM]":"25.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.7","Cell RNA - hTERT-HME1 [nTPM]":"24.9","Cell RNA - hTERT-RPE1 [nTPM]":"34.5","Cell RNA - HUVEC TERT2 [nTPM]":"39.2","Cell RNA - JURKAT [nTPM]":"7.0","Cell RNA - K-562 [nTPM]":"7.5","Cell RNA - Karpas-707 [nTPM]":"22.1","Cell RNA - LHCN-M2 [nTPM]":"40.4","Cell RNA - MCF7 [nTPM]":"10.0","Cell RNA - MOLT-4 [nTPM]":"14.8","Cell RNA - NB-4 [nTPM]":"7.2","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"16.3","Cell RNA - PC-3 [nTPM]":"5.4","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"16.1","Cell RNA - RPMI-8226 [nTPM]":"7.7","Cell RNA - RPTEC TERT1 [nTPM]":"36.1","Cell RNA - RT4 [nTPM]":"22.8","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"14.0","Cell RNA - SiHa [nTPM]":"39.0","Cell RNA - SK-BR-3 [nTPM]":"12.6","Cell RNA - SK-MEL-30 [nTPM]":"17.4","Cell RNA - SuSa [nTPM]":"19.0","Cell RNA - T-47d [nTPM]":"43.7","Cell RNA - THP-1 [nTPM]":"20.9","Cell RNA - TIME [nTPM]":"46.3","Cell RNA - U-138 MG [nTPM]":"33.2","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"20.9","Cell RNA - U-251 MG [nTPM]":"12.7","Cell RNA - U-266\/70 [nTPM]":"17.9","Cell RNA - U-266\/84 [nTPM]":"18.2","Cell RNA - U-698 [nTPM]":"6.1","Cell RNA - U-87 MG [nTPM]":"26.8","Cell RNA - U-937 [nTPM]":"6.3","Cell RNA - WM-115 [nTPM]":"20.8","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"8.8","Blood RNA - eosinophil [nTPM]":"9.4","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"5.4","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"15.8","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"8.8","Blood RNA - non-classical monocyte [nTPM]":"8.6","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"5.0","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"10.6","Brain RNA - cerebral cortex [nTPM]":"13.5","Brain RNA - hippocampal formation [nTPM]":"13.3","Brain RNA - hypothalamus [nTPM]":"17.6","Brain RNA - medulla oblongata [nTPM]":"13.3","Brain RNA - midbrain [nTPM]":"12.0","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"15.8","Brain RNA - white matter [nTPM]":"13.0","Single Cell Type RNA - Adipocytes [nTPM]":"39.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.9","Single Cell Type RNA - Astrocytes [nTPM]":"48.0","Single Cell Type RNA - B-cells [nTPM]":"26.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"50.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"17.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.2","Single Cell Type RNA - dendritic cells [nTPM]":"30.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"26.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.1","Single Cell Type RNA - Endothelial cells [nTPM]":"37.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.1","Single Cell Type RNA - Erythroid cells [nTPM]":"15.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.4","Single Cell Type RNA - Fibroblasts [nTPM]":"34.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.5","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"51.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"23.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.2","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"76.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"34.3","Single Cell Type RNA - Langerhans cells [nTPM]":"58.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"35.1","Single Cell Type RNA - Macrophages [nTPM]":"43.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"33.5","Single Cell Type RNA - Muller glia cells [nTPM]":"13.5","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.9","Single Cell Type RNA - Paneth cells [nTPM]":"17.0","Single Cell Type RNA - Peritubular cells [nTPM]":"31.6","Single Cell Type RNA - Plasma cells [nTPM]":"19.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.1","Single Cell Type RNA - T-cells [nTPM]":"25.0","Single Cell Type RNA - Theca cells [nTPM]":"37.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.7","Single Cell Type RNA - Urothelial cells [nTPM]":"17.7"},{"Gene":"HYAL1","Gene synonym":["HYAL-1","LUCA1"],"Ensembl":"ENSG00000114378","Gene description":"Hyaluronidase 1","Uniprot":["Q12794"],"Chromosome":"3","Position":"50299890-50312381","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"201.6","lymphoid tissue":"95.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"30.0","Hepatic stellate cells":"33.2","Hepatocytes":"137.1","Proximal tubular cells":"58.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"37.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"3.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Hep G2":"100.9","SK-BR-3":"28.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002112"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"590000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002112":"AB_1857412"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.07e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.56e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.4","Tissue RNA - adrenal gland [nTPM]":"21.5","Tissue RNA - amygdala [nTPM]":"5.0","Tissue RNA - appendix [nTPM]":"2.8","Tissue RNA - basal ganglia [nTPM]":"4.5","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"9.2","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"10.8","Tissue RNA - choroid plexus [nTPM]":"18.3","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"8.2","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"68.2","Tissue RNA - hippocampal formation [nTPM]":"4.5","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"49.4","Tissue RNA - liver [nTPM]":"201.6","Tissue RNA - lung [nTPM]":"30.7","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"5.4","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"3.0","Tissue RNA - pancreas [nTPM]":"9.4","Tissue RNA - parathyroid gland [nTPM]":"19.9","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"5.6","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"7.3","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"15.0","Tissue RNA - skin 1 [nTPM]":"21.1","Tissue RNA - small intestine [nTPM]":"6.0","Tissue RNA - smooth muscle [nTPM]":"5.9","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"95.1","Tissue RNA - stomach 1 [nTPM]":"19.4","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"5.8","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"8.3","Tissue RNA - tongue [nTPM]":"19.0","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"4.8","Tissue RNA - vagina [nTPM]":"12.3","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"2.9","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"11.4","Cell RNA - CAPAN-2 [nTPM]":"3.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"6.6","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"8.6","Cell RNA - Hep G2 [nTPM]":"100.9","Cell RNA - HHSteC [nTPM]":"4.4","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"3.9","Cell RNA - hTCEpi [nTPM]":"13.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"7.1","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"28.0","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"2.4","Cell RNA - T-47d [nTPM]":"2.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"1.9","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"3.1","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"5.0","Brain RNA - basal ganglia [nTPM]":"4.5","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"4.5","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"5.4","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"5.6","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"5.8","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"18.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"2.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"16.5","Single Cell Type RNA - Early spermatids [nTPM]":"8.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"25.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"137.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"7.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"58.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"7.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"IDS","Gene synonym":["ID2S","SIDS"],"Ensembl":"ENSG00000010404","Gene description":"Iduronate 2-sulfatase","Uniprot":["P22304"],"Chromosome":"X","Position":"149476988-149521096","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"323.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"amygdala":"194.3","basal ganglia":"212.9","cerebral cortex":"323.4","hippocampal formation":"320.5","white matter":"109.4"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078003"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078003":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Tissue RNA - adipose tissue [nTPM]":"32.7","Tissue RNA - adrenal gland [nTPM]":"43.3","Tissue RNA - amygdala [nTPM]":"194.3","Tissue RNA - appendix [nTPM]":"29.5","Tissue RNA - basal ganglia [nTPM]":"212.9","Tissue RNA - bone marrow [nTPM]":"47.6","Tissue RNA - breast [nTPM]":"27.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"323.4","Tissue RNA - cervix [nTPM]":"37.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"35.7","Tissue RNA - duodenum [nTPM]":"21.1","Tissue RNA - endometrium 1 [nTPM]":"35.1","Tissue RNA - epididymis [nTPM]":"43.5","Tissue RNA - esophagus [nTPM]":"26.1","Tissue RNA - fallopian tube [nTPM]":"35.7","Tissue RNA - gallbladder [nTPM]":"26.3","Tissue RNA - heart muscle [nTPM]":"42.2","Tissue RNA - hippocampal formation [nTPM]":"320.5","Tissue RNA - hypothalamus [nTPM]":"25.7","Tissue RNA - kidney [nTPM]":"22.7","Tissue RNA - liver [nTPM]":"15.8","Tissue RNA - lung [nTPM]":"40.5","Tissue RNA - lymph node [nTPM]":"31.0","Tissue RNA - medulla oblongata [nTPM]":"9.7","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"45.4","Tissue RNA - pancreas [nTPM]":"23.3","Tissue RNA - parathyroid gland [nTPM]":"57.0","Tissue RNA - pituitary gland [nTPM]":"67.8","Tissue RNA - placenta [nTPM]":"16.3","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"29.4","Tissue RNA - rectum [nTPM]":"20.8","Tissue RNA - retina [nTPM]":"48.6","Tissue RNA - salivary gland [nTPM]":"24.7","Tissue RNA - seminal vesicle [nTPM]":"41.0","Tissue RNA - skeletal muscle [nTPM]":"25.1","Tissue RNA - skin 1 [nTPM]":"37.1","Tissue RNA - small intestine [nTPM]":"27.9","Tissue RNA - smooth muscle [nTPM]":"30.5","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"34.1","Tissue RNA - stomach 1 [nTPM]":"23.0","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"32.3","Tissue RNA - thymus [nTPM]":"17.2","Tissue RNA - thyroid gland [nTPM]":"27.2","Tissue RNA - tongue [nTPM]":"38.9","Tissue RNA - tonsil [nTPM]":"36.0","Tissue RNA - urinary bladder [nTPM]":"32.8","Tissue RNA - vagina [nTPM]":"31.5","Tissue RNA - white matter [nTPM]":"109.4","Cell RNA - A-431 [nTPM]":"46.4","Cell RNA - A549 [nTPM]":"50.7","Cell RNA - AF22 [nTPM]":"19.6","Cell RNA - AN3-CA [nTPM]":"12.7","Cell RNA - ASC diff [nTPM]":"22.1","Cell RNA - ASC TERT1 [nTPM]":"40.9","Cell RNA - BEWO [nTPM]":"9.2","Cell RNA - BJ [nTPM]":"26.6","Cell RNA - BJ hTERT+ [nTPM]":"67.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.9","Cell RNA - CACO-2 [nTPM]":"10.2","Cell RNA - CAPAN-2 [nTPM]":"32.7","Cell RNA - Daudi [nTPM]":"110.0","Cell RNA - EFO-21 [nTPM]":"69.6","Cell RNA - fHDF\/TERT166 [nTPM]":"38.3","Cell RNA - GAMG [nTPM]":"49.1","Cell RNA - HaCaT [nTPM]":"22.6","Cell RNA - HAP1 [nTPM]":"21.3","Cell RNA - HBEC3-KT [nTPM]":"40.5","Cell RNA - HBF TERT88 [nTPM]":"30.1","Cell RNA - HDLM-2 [nTPM]":"40.8","Cell RNA - HEK 293 [nTPM]":"17.7","Cell RNA - HEL [nTPM]":"11.5","Cell RNA - HeLa [nTPM]":"14.7","Cell RNA - Hep G2 [nTPM]":"5.7","Cell RNA - HHSteC [nTPM]":"17.8","Cell RNA - HL-60 [nTPM]":"18.8","Cell RNA - HMC-1 [nTPM]":"101.3","Cell RNA - HSkMC [nTPM]":"21.4","Cell RNA - hTCEpi [nTPM]":"19.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.9","Cell RNA - hTERT-HME1 [nTPM]":"33.1","Cell RNA - hTERT-RPE1 [nTPM]":"95.5","Cell RNA - HUVEC TERT2 [nTPM]":"37.8","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"5.7","Cell RNA - Karpas-707 [nTPM]":"76.6","Cell RNA - LHCN-M2 [nTPM]":"34.7","Cell RNA - MCF7 [nTPM]":"57.9","Cell RNA - MOLT-4 [nTPM]":"19.6","Cell RNA - NB-4 [nTPM]":"9.3","Cell RNA - NTERA-2 [nTPM]":"17.5","Cell RNA - OE19 [nTPM]":"28.8","Cell RNA - PC-3 [nTPM]":"34.3","Cell RNA - REH [nTPM]":"12.4","Cell RNA - RH-30 [nTPM]":"19.4","Cell RNA - RPMI-8226 [nTPM]":"20.7","Cell RNA - RPTEC TERT1 [nTPM]":"27.8","Cell RNA - RT4 [nTPM]":"10.5","Cell RNA - SCLC-21H [nTPM]":"28.9","Cell RNA - SH-SY5Y [nTPM]":"67.6","Cell RNA - SiHa [nTPM]":"9.8","Cell RNA - SK-BR-3 [nTPM]":"22.1","Cell RNA - SK-MEL-30 [nTPM]":"32.0","Cell RNA - SuSa [nTPM]":"33.2","Cell RNA - T-47d [nTPM]":"6.9","Cell RNA - THP-1 [nTPM]":"7.9","Cell RNA - TIME [nTPM]":"44.3","Cell RNA - U-138 MG [nTPM]":"29.9","Cell RNA - U-2 OS [nTPM]":"31.3","Cell RNA - U-2197 [nTPM]":"50.1","Cell RNA - U-251 MG [nTPM]":"70.8","Cell RNA - U-266\/70 [nTPM]":"54.5","Cell RNA - U-266\/84 [nTPM]":"47.3","Cell RNA - U-698 [nTPM]":"79.3","Cell RNA - U-87 MG [nTPM]":"138.0","Cell RNA - U-937 [nTPM]":"44.3","Cell RNA - WM-115 [nTPM]":"22.1","Blood RNA - basophil [nTPM]":"117.5","Blood RNA - classical monocyte [nTPM]":"56.9","Blood RNA - eosinophil [nTPM]":"171.7","Blood RNA - gdT-cell [nTPM]":"70.9","Blood RNA - intermediate monocyte [nTPM]":"63.0","Blood RNA - MAIT T-cell [nTPM]":"53.2","Blood RNA - memory B-cell [nTPM]":"35.2","Blood RNA - memory CD4 T-cell [nTPM]":"43.1","Blood RNA - memory CD8 T-cell [nTPM]":"54.0","Blood RNA - myeloid DC [nTPM]":"48.7","Blood RNA - naive B-cell [nTPM]":"27.0","Blood RNA - naive CD4 T-cell [nTPM]":"28.4","Blood RNA - naive CD8 T-cell [nTPM]":"42.9","Blood RNA - neutrophil [nTPM]":"261.1","Blood RNA - NK-cell [nTPM]":"37.2","Blood RNA - non-classical monocyte [nTPM]":"73.9","Blood RNA - plasmacytoid DC [nTPM]":"36.8","Blood RNA - T-reg [nTPM]":"74.0","Blood RNA - total PBMC [nTPM]":"63.0","Brain RNA - amygdala [nTPM]":"194.3","Brain RNA - basal ganglia [nTPM]":"212.9","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"323.4","Brain RNA - hippocampal formation [nTPM]":"320.5","Brain RNA - hypothalamus [nTPM]":"25.7","Brain RNA - medulla oblongata [nTPM]":"9.7","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"32.3","Brain RNA - white matter [nTPM]":"109.4","Single Cell Type RNA - Adipocytes [nTPM]":"53.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"99.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"64.4","Single Cell Type RNA - Astrocytes [nTPM]":"55.8","Single Cell Type RNA - B-cells [nTPM]":"150.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"60.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"44.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"178.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"43.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"58.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"82.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.2","Single Cell Type RNA - dendritic cells [nTPM]":"158.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"66.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"50.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.8","Single Cell Type RNA - Endothelial cells [nTPM]":"44.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"168.4","Single Cell Type RNA - Erythroid cells [nTPM]":"19.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"232.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"74.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.7","Single Cell Type RNA - Fibroblasts [nTPM]":"78.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"49.5","Single Cell Type RNA - granulocytes [nTPM]":"226.2","Single Cell Type RNA - Granulosa cells [nTPM]":"25.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"60.3","Single Cell Type RNA - Hepatocytes [nTPM]":"33.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.0","Single Cell Type RNA - Horizontal cells [nTPM]":"222.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"243.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.0","Single Cell Type RNA - Ionocytes [nTPM]":"73.2","Single Cell Type RNA - Kupffer cells [nTPM]":"94.8","Single Cell Type RNA - Langerhans cells [nTPM]":"109.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"72.7","Single Cell Type RNA - Macrophages [nTPM]":"98.4","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"63.7","Single Cell Type RNA - monocytes [nTPM]":"120.9","Single Cell Type RNA - Muller glia cells [nTPM]":"55.0","Single Cell Type RNA - NK-cells [nTPM]":"146.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"95.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"85.0","Single Cell Type RNA - Paneth cells [nTPM]":"50.3","Single Cell Type RNA - Peritubular cells [nTPM]":"89.5","Single Cell Type RNA - Plasma cells [nTPM]":"98.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"71.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"74.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"112.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.5","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"68.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"65.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"143.0","Single Cell Type RNA - T-cells [nTPM]":"183.9","Single Cell Type RNA - Theca cells [nTPM]":"16.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.1","Single Cell Type RNA - Urothelial cells [nTPM]":"96.9"},{"Gene":"IDUA","Gene synonym":["MPS1","MPSI"],"Ensembl":"ENSG00000127415","Gene description":"Alpha-L-iduronidase","Uniprot":["P35475"],"Chromosome":"4","Position":"986997-1004564","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"19.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/70":"29.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025901","HPA046979","HPA054254"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB025901":null,"HPA046979":"AB_2679888","HPA054254":"AB_2682429"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.87e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.04e-5"},"Tissue RNA - adipose tissue [nTPM]":"13.5","Tissue RNA - adrenal gland [nTPM]":"17.6","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"16.1","Tissue RNA - cerebellum [nTPM]":"9.2","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"10.3","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"15.4","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"11.6","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"15.9","Tissue RNA - liver [nTPM]":"13.6","Tissue RNA - lung [nTPM]":"13.9","Tissue RNA - lymph node [nTPM]":"3.5","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"17.0","Tissue RNA - pancreas [nTPM]":"21.0","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"17.2","Tissue RNA - placenta [nTPM]":"1.7","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"18.5","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"16.6","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"8.9","Tissue RNA - small intestine [nTPM]":"14.3","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"18.9","Tissue RNA - stomach 1 [nTPM]":"17.1","Tissue RNA - testis [nTPM]":"5.6","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"17.0","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"1.3","Tissue RNA - urinary bladder [nTPM]":"12.0","Tissue RNA - vagina [nTPM]":"13.9","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"1.8","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"1.1","Cell RNA - ASC diff [nTPM]":"12.7","Cell RNA - ASC TERT1 [nTPM]":"3.6","Cell RNA - BEWO [nTPM]":"5.3","Cell RNA - BJ [nTPM]":"10.7","Cell RNA - BJ hTERT+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"10.7","Cell RNA - fHDF\/TERT166 [nTPM]":"5.0","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"6.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"5.8","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"4.6","Cell RNA - HSkMC [nTPM]":"9.3","Cell RNA - hTCEpi [nTPM]":"3.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"2.2","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"11.9","Cell RNA - PC-3 [nTPM]":"5.5","Cell RNA - REH [nTPM]":"2.7","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"3.5","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"3.3","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"5.7","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"1.2","Cell RNA - THP-1 [nTPM]":"2.3","Cell RNA - TIME [nTPM]":"9.3","Cell RNA - U-138 MG [nTPM]":"9.0","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"2.6","Cell RNA - U-251 MG [nTPM]":"1.2","Cell RNA - U-266\/70 [nTPM]":"29.0","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"7.8","Cell RNA - U-937 [nTPM]":"3.3","Cell RNA - WM-115 [nTPM]":"1.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"9.2","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"8.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"5.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"4.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.7","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"13.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.6","Single Cell Type RNA - Macrophages [nTPM]":"7.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"6.9","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"15.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"5.6","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"7.9"},{"Gene":"LAMP2","Gene synonym":["CD107b"],"Ensembl":"ENSG00000005893","Gene description":"Lysosomal associated membrane protein 2","Uniprot":["P13473"],"Chromosome":"X","Position":"120426148-120469365","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"507.2","Syncytiotrophoblasts":"402.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"556.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"556.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005272","HPA029100"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"520000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB005272":"AB_647855","HPA029100":"AB_10795022"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"},"Tissue RNA - adipose tissue [nTPM]":"54.2","Tissue RNA - adrenal gland [nTPM]":"68.7","Tissue RNA - amygdala [nTPM]":"80.3","Tissue RNA - appendix [nTPM]":"38.3","Tissue RNA - basal ganglia [nTPM]":"144.2","Tissue RNA - bone marrow [nTPM]":"62.8","Tissue RNA - breast [nTPM]":"56.3","Tissue RNA - cerebellum [nTPM]":"109.1","Tissue RNA - cerebral cortex [nTPM]":"135.5","Tissue RNA - cervix [nTPM]":"64.9","Tissue RNA - choroid plexus [nTPM]":"52.7","Tissue RNA - colon [nTPM]":"39.2","Tissue RNA - duodenum [nTPM]":"44.3","Tissue RNA - endometrium 1 [nTPM]":"44.3","Tissue RNA - epididymis [nTPM]":"55.1","Tissue RNA - esophagus [nTPM]":"79.4","Tissue RNA - fallopian tube [nTPM]":"44.1","Tissue RNA - gallbladder [nTPM]":"69.6","Tissue RNA - heart muscle [nTPM]":"45.3","Tissue RNA - hippocampal formation [nTPM]":"81.6","Tissue RNA - hypothalamus [nTPM]":"101.8","Tissue RNA - kidney [nTPM]":"85.5","Tissue RNA - liver [nTPM]":"129.9","Tissue RNA - lung [nTPM]":"54.2","Tissue RNA - lymph node [nTPM]":"34.1","Tissue RNA - medulla oblongata [nTPM]":"113.0","Tissue RNA - midbrain [nTPM]":"112.6","Tissue RNA - ovary [nTPM]":"49.1","Tissue RNA - pancreas [nTPM]":"57.8","Tissue RNA - parathyroid gland [nTPM]":"64.2","Tissue RNA - pituitary gland [nTPM]":"32.2","Tissue RNA - placenta [nTPM]":"47.9","Tissue RNA - pons [nTPM]":"120.6","Tissue RNA - prostate [nTPM]":"62.2","Tissue RNA - rectum [nTPM]":"35.0","Tissue RNA - retina [nTPM]":"32.6","Tissue RNA - salivary gland [nTPM]":"102.1","Tissue RNA - seminal vesicle [nTPM]":"55.1","Tissue RNA - skeletal muscle [nTPM]":"111.6","Tissue RNA - skin 1 [nTPM]":"67.2","Tissue RNA - small intestine [nTPM]":"42.4","Tissue RNA - smooth muscle [nTPM]":"42.8","Tissue RNA - spinal cord [nTPM]":"100.5","Tissue RNA - spleen [nTPM]":"39.5","Tissue RNA - stomach 1 [nTPM]":"51.8","Tissue RNA - testis [nTPM]":"26.2","Tissue RNA - thalamus [nTPM]":"100.9","Tissue RNA - thymus [nTPM]":"59.3","Tissue RNA - thyroid gland [nTPM]":"61.7","Tissue RNA - tongue [nTPM]":"67.4","Tissue RNA - tonsil [nTPM]":"36.6","Tissue RNA - urinary bladder [nTPM]":"43.4","Tissue RNA - vagina [nTPM]":"63.3","Tissue RNA - white matter [nTPM]":"211.7","Cell RNA - A-431 [nTPM]":"53.8","Cell RNA - A549 [nTPM]":"47.5","Cell RNA - AF22 [nTPM]":"40.1","Cell RNA - AN3-CA [nTPM]":"49.7","Cell RNA - ASC diff [nTPM]":"367.0","Cell RNA - ASC TERT1 [nTPM]":"140.9","Cell RNA - BEWO [nTPM]":"91.5","Cell RNA - BJ [nTPM]":"79.3","Cell RNA - BJ hTERT+ [nTPM]":"130.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"77.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"134.4","Cell RNA - CACO-2 [nTPM]":"42.7","Cell RNA - CAPAN-2 [nTPM]":"90.3","Cell RNA - Daudi [nTPM]":"47.9","Cell RNA - EFO-21 [nTPM]":"73.1","Cell RNA - fHDF\/TERT166 [nTPM]":"132.7","Cell RNA - GAMG [nTPM]":"236.2","Cell RNA - HaCaT [nTPM]":"84.9","Cell RNA - HAP1 [nTPM]":"56.7","Cell RNA - HBEC3-KT [nTPM]":"67.2","Cell RNA - HBF TERT88 [nTPM]":"125.5","Cell RNA - HDLM-2 [nTPM]":"43.6","Cell RNA - HEK 293 [nTPM]":"37.2","Cell RNA - HEL [nTPM]":"35.8","Cell RNA - HeLa [nTPM]":"46.4","Cell RNA - Hep G2 [nTPM]":"54.3","Cell RNA - HHSteC [nTPM]":"148.1","Cell RNA - HL-60 [nTPM]":"158.9","Cell RNA - HMC-1 [nTPM]":"73.2","Cell RNA - HSkMC [nTPM]":"151.5","Cell RNA - hTCEpi [nTPM]":"114.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"108.1","Cell RNA - hTERT-HME1 [nTPM]":"75.1","Cell RNA - hTERT-RPE1 [nTPM]":"188.6","Cell RNA - HUVEC TERT2 [nTPM]":"107.5","Cell RNA - JURKAT [nTPM]":"32.5","Cell RNA - K-562 [nTPM]":"42.1","Cell RNA - Karpas-707 [nTPM]":"122.9","Cell RNA - LHCN-M2 [nTPM]":"117.2","Cell RNA - MCF7 [nTPM]":"79.3","Cell RNA - MOLT-4 [nTPM]":"45.3","Cell RNA - NB-4 [nTPM]":"80.2","Cell RNA - NTERA-2 [nTPM]":"29.0","Cell RNA - OE19 [nTPM]":"63.7","Cell RNA - PC-3 [nTPM]":"42.6","Cell RNA - REH [nTPM]":"35.1","Cell RNA - RH-30 [nTPM]":"65.3","Cell RNA - RPMI-8226 [nTPM]":"73.1","Cell RNA - RPTEC TERT1 [nTPM]":"102.3","Cell RNA - RT4 [nTPM]":"36.9","Cell RNA - SCLC-21H [nTPM]":"14.0","Cell RNA - SH-SY5Y [nTPM]":"22.6","Cell RNA - SiHa [nTPM]":"99.7","Cell RNA - SK-BR-3 [nTPM]":"93.0","Cell RNA - SK-MEL-30 [nTPM]":"196.5","Cell RNA - SuSa [nTPM]":"57.4","Cell RNA - T-47d [nTPM]":"64.7","Cell RNA - THP-1 [nTPM]":"173.0","Cell RNA - TIME [nTPM]":"122.5","Cell RNA - U-138 MG [nTPM]":"114.1","Cell RNA - U-2 OS [nTPM]":"58.7","Cell RNA - U-2197 [nTPM]":"176.2","Cell RNA - U-251 MG [nTPM]":"261.5","Cell RNA - U-266\/70 [nTPM]":"68.5","Cell RNA - U-266\/84 [nTPM]":"78.6","Cell RNA - U-698 [nTPM]":"30.2","Cell RNA - U-87 MG [nTPM]":"131.4","Cell RNA - U-937 [nTPM]":"182.4","Cell RNA - WM-115 [nTPM]":"284.4","Blood RNA - basophil [nTPM]":"30.6","Blood RNA - classical monocyte [nTPM]":"114.9","Blood RNA - eosinophil [nTPM]":"224.1","Blood RNA - gdT-cell [nTPM]":"27.1","Blood RNA - intermediate monocyte [nTPM]":"97.1","Blood RNA - MAIT T-cell [nTPM]":"20.6","Blood RNA - memory B-cell [nTPM]":"17.1","Blood RNA - memory CD4 T-cell [nTPM]":"24.3","Blood RNA - memory CD8 T-cell [nTPM]":"24.5","Blood RNA - myeloid DC [nTPM]":"64.2","Blood RNA - naive B-cell [nTPM]":"22.5","Blood RNA - naive CD4 T-cell [nTPM]":"23.4","Blood RNA - naive CD8 T-cell [nTPM]":"21.8","Blood RNA - neutrophil [nTPM]":"556.6","Blood RNA - NK-cell [nTPM]":"31.8","Blood RNA - non-classical monocyte [nTPM]":"96.2","Blood RNA - plasmacytoid DC [nTPM]":"33.4","Blood RNA - T-reg [nTPM]":"33.4","Blood RNA - total PBMC [nTPM]":"66.3","Brain RNA - amygdala [nTPM]":"80.3","Brain RNA - basal ganglia [nTPM]":"144.2","Brain RNA - cerebellum [nTPM]":"109.1","Brain RNA - cerebral cortex [nTPM]":"135.5","Brain RNA - hippocampal formation [nTPM]":"81.6","Brain RNA - hypothalamus [nTPM]":"101.8","Brain RNA - medulla oblongata [nTPM]":"113.0","Brain RNA - midbrain [nTPM]":"112.6","Brain RNA - pons [nTPM]":"120.6","Brain RNA - spinal cord [nTPM]":"100.5","Brain RNA - thalamus [nTPM]":"100.9","Brain RNA - white matter [nTPM]":"211.7","Single Cell Type RNA - Adipocytes [nTPM]":"75.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"53.8","Single Cell Type RNA - Astrocytes [nTPM]":"52.2","Single Cell Type RNA - B-cells [nTPM]":"29.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"100.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"92.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"262.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"64.9","Single Cell Type RNA - Bipolar cells [nTPM]":"17.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"74.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"58.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"173.0","Single Cell Type RNA - Club cells [nTPM]":"155.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"66.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"163.7","Single Cell Type RNA - dendritic cells [nTPM]":"44.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"52.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"217.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"103.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"74.1","Single Cell Type RNA - Endothelial cells [nTPM]":"69.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.6","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"70.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"128.3","Single Cell Type RNA - Fibroblasts [nTPM]":"113.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"168.1","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"46.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"87.8","Single Cell Type RNA - Hepatocytes [nTPM]":"176.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"208.0","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"40.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.6","Single Cell Type RNA - Ionocytes [nTPM]":"134.3","Single Cell Type RNA - Kupffer cells [nTPM]":"133.1","Single Cell Type RNA - Langerhans cells [nTPM]":"80.4","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"113.7","Single Cell Type RNA - Macrophages [nTPM]":"135.5","Single Cell Type RNA - Melanocytes [nTPM]":"131.6","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"132.7","Single Cell Type RNA - Muller glia cells [nTPM]":"116.3","Single Cell Type RNA - NK-cells [nTPM]":"50.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"57.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"507.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"62.5","Single Cell Type RNA - Paneth cells [nTPM]":"54.4","Single Cell Type RNA - Peritubular cells [nTPM]":"109.9","Single Cell Type RNA - Plasma cells [nTPM]":"66.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"100.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"97.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"154.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"75.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.5","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"176.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"61.7","Single Cell Type RNA - Spermatocytes [nTPM]":"6.4","Single Cell Type RNA - Spermatogonia [nTPM]":"13.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"78.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"136.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"402.4","Single Cell Type RNA - T-cells [nTPM]":"34.5","Single Cell Type RNA - Theca cells [nTPM]":"71.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.8","Single Cell Type RNA - Urothelial cells [nTPM]":"92.9"},{"Gene":"LIPA","Gene synonym":["CESD","LAL"],"Ensembl":"ENSG00000107798","Gene description":"Lipase A, lysosomal acid type","Uniprot":["P38571"],"Chromosome":"10","Position":"89213569-89414557","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"398.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"515.0","Kupffer cells":"714.8","Macrophages":"303.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"167.3","intermediate monocyte":"355.1","myeloid DC":"123.6","non-classical monocyte":"198.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"123.6","monocytes":"355.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"354.4","AN3-CA":"367.8","ASC TERT1":"450.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034892","HPA057052"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Nucleoplasm","Nucleoli fibrillar center"],"Antibody RRID":{"CAB034892":"AB_784329","HPA057052":"AB_2683322"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"76.0","Tissue RNA - adrenal gland [nTPM]":"46.3","Tissue RNA - amygdala [nTPM]":"43.5","Tissue RNA - appendix [nTPM]":"66.7","Tissue RNA - basal ganglia [nTPM]":"65.2","Tissue RNA - bone marrow [nTPM]":"39.8","Tissue RNA - breast [nTPM]":"47.8","Tissue RNA - cerebellum [nTPM]":"64.1","Tissue RNA - cerebral cortex [nTPM]":"74.4","Tissue RNA - cervix [nTPM]":"54.0","Tissue RNA - choroid plexus [nTPM]":"39.0","Tissue RNA - colon [nTPM]":"67.7","Tissue RNA - duodenum [nTPM]":"167.6","Tissue RNA - endometrium 1 [nTPM]":"38.8","Tissue RNA - epididymis [nTPM]":"21.7","Tissue RNA - esophagus [nTPM]":"28.6","Tissue RNA - fallopian tube [nTPM]":"37.8","Tissue RNA - gallbladder [nTPM]":"83.5","Tissue RNA - heart muscle [nTPM]":"24.2","Tissue RNA - hippocampal formation [nTPM]":"43.5","Tissue RNA - hypothalamus [nTPM]":"53.1","Tissue RNA - kidney [nTPM]":"44.9","Tissue RNA - liver [nTPM]":"218.9","Tissue RNA - lung [nTPM]":"169.5","Tissue RNA - lymph node [nTPM]":"159.3","Tissue RNA - medulla oblongata [nTPM]":"74.7","Tissue RNA - midbrain [nTPM]":"55.5","Tissue RNA - ovary [nTPM]":"32.7","Tissue RNA - pancreas [nTPM]":"21.4","Tissue RNA - parathyroid gland [nTPM]":"68.9","Tissue RNA - pituitary gland [nTPM]":"12.7","Tissue RNA - placenta [nTPM]":"79.1","Tissue RNA - pons [nTPM]":"82.2","Tissue RNA - prostate [nTPM]":"30.7","Tissue RNA - rectum [nTPM]":"72.0","Tissue RNA - retina [nTPM]":"12.6","Tissue RNA - salivary gland [nTPM]":"22.5","Tissue RNA - seminal vesicle [nTPM]":"33.8","Tissue RNA - skeletal muscle [nTPM]":"11.8","Tissue RNA - skin 1 [nTPM]":"18.7","Tissue RNA - small intestine [nTPM]":"227.5","Tissue RNA - smooth muscle [nTPM]":"47.7","Tissue RNA - spinal cord [nTPM]":"65.4","Tissue RNA - spleen [nTPM]":"398.4","Tissue RNA - stomach 1 [nTPM]":"34.3","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"57.0","Tissue RNA - thymus [nTPM]":"44.5","Tissue RNA - thyroid gland [nTPM]":"31.6","Tissue RNA - tongue [nTPM]":"22.5","Tissue RNA - tonsil [nTPM]":"45.5","Tissue RNA - urinary bladder [nTPM]":"58.4","Tissue RNA - vagina [nTPM]":"19.3","Tissue RNA - white matter [nTPM]":"115.5","Cell RNA - A-431 [nTPM]":"354.4","Cell RNA - A549 [nTPM]":"49.4","Cell RNA - AF22 [nTPM]":"30.7","Cell RNA - AN3-CA [nTPM]":"367.8","Cell RNA - ASC diff [nTPM]":"343.5","Cell RNA - ASC TERT1 [nTPM]":"450.8","Cell RNA - BEWO [nTPM]":"10.0","Cell RNA - BJ [nTPM]":"171.4","Cell RNA - BJ hTERT+ [nTPM]":"194.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"121.5","Cell RNA - CACO-2 [nTPM]":"18.6","Cell RNA - CAPAN-2 [nTPM]":"176.6","Cell RNA - Daudi [nTPM]":"63.9","Cell RNA - EFO-21 [nTPM]":"34.0","Cell RNA - fHDF\/TERT166 [nTPM]":"264.4","Cell RNA - GAMG [nTPM]":"73.7","Cell RNA - HaCaT [nTPM]":"338.7","Cell RNA - HAP1 [nTPM]":"13.8","Cell RNA - HBEC3-KT [nTPM]":"92.8","Cell RNA - HBF TERT88 [nTPM]":"53.6","Cell RNA - HDLM-2 [nTPM]":"86.1","Cell RNA - HEK 293 [nTPM]":"34.7","Cell RNA - HEL [nTPM]":"25.1","Cell RNA - HeLa [nTPM]":"19.1","Cell RNA - Hep G2 [nTPM]":"81.5","Cell RNA - HHSteC [nTPM]":"87.6","Cell RNA - HL-60 [nTPM]":"48.8","Cell RNA - HMC-1 [nTPM]":"48.9","Cell RNA - HSkMC [nTPM]":"190.4","Cell RNA - hTCEpi [nTPM]":"69.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"72.9","Cell RNA - hTERT-HME1 [nTPM]":"40.6","Cell RNA - hTERT-RPE1 [nTPM]":"88.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.9","Cell RNA - JURKAT [nTPM]":"45.4","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"108.5","Cell RNA - LHCN-M2 [nTPM]":"58.3","Cell RNA - MCF7 [nTPM]":"28.2","Cell RNA - MOLT-4 [nTPM]":"45.7","Cell RNA - NB-4 [nTPM]":"34.6","Cell RNA - NTERA-2 [nTPM]":"22.7","Cell RNA - OE19 [nTPM]":"62.4","Cell RNA - PC-3 [nTPM]":"60.0","Cell RNA - REH [nTPM]":"26.4","Cell RNA - RH-30 [nTPM]":"39.0","Cell RNA - RPMI-8226 [nTPM]":"60.5","Cell RNA - RPTEC TERT1 [nTPM]":"69.2","Cell RNA - RT4 [nTPM]":"50.9","Cell RNA - SCLC-21H [nTPM]":"10.5","Cell RNA - SH-SY5Y [nTPM]":"21.8","Cell RNA - SiHa [nTPM]":"41.4","Cell RNA - SK-BR-3 [nTPM]":"49.9","Cell RNA - SK-MEL-30 [nTPM]":"133.9","Cell RNA - SuSa [nTPM]":"20.4","Cell RNA - T-47d [nTPM]":"64.4","Cell RNA - THP-1 [nTPM]":"65.8","Cell RNA - TIME [nTPM]":"26.2","Cell RNA - U-138 MG [nTPM]":"58.8","Cell RNA - U-2 OS [nTPM]":"15.5","Cell RNA - U-2197 [nTPM]":"132.1","Cell RNA - U-251 MG [nTPM]":"44.6","Cell RNA - U-266\/70 [nTPM]":"60.0","Cell RNA - U-266\/84 [nTPM]":"65.7","Cell RNA - U-698 [nTPM]":"25.8","Cell RNA - U-87 MG [nTPM]":"71.4","Cell RNA - U-937 [nTPM]":"112.9","Cell RNA - WM-115 [nTPM]":"82.1","Blood RNA - basophil [nTPM]":"4.2","Blood RNA - classical monocyte [nTPM]":"167.3","Blood RNA - eosinophil [nTPM]":"16.9","Blood RNA - gdT-cell [nTPM]":"40.0","Blood RNA - intermediate monocyte [nTPM]":"355.1","Blood RNA - MAIT T-cell [nTPM]":"40.6","Blood RNA - memory B-cell [nTPM]":"31.9","Blood RNA - memory CD4 T-cell [nTPM]":"35.8","Blood RNA - memory CD8 T-cell [nTPM]":"38.8","Blood RNA - myeloid DC [nTPM]":"123.6","Blood RNA - naive B-cell [nTPM]":"33.4","Blood RNA - naive CD4 T-cell [nTPM]":"36.7","Blood RNA - naive CD8 T-cell [nTPM]":"40.4","Blood RNA - neutrophil [nTPM]":"7.1","Blood RNA - NK-cell [nTPM]":"29.8","Blood RNA - non-classical monocyte [nTPM]":"198.5","Blood RNA - plasmacytoid DC [nTPM]":"25.0","Blood RNA - T-reg [nTPM]":"38.2","Blood RNA - total PBMC [nTPM]":"159.6","Brain RNA - amygdala [nTPM]":"43.5","Brain RNA - basal ganglia [nTPM]":"65.2","Brain RNA - cerebellum [nTPM]":"64.1","Brain RNA - cerebral cortex [nTPM]":"74.4","Brain RNA - hippocampal formation [nTPM]":"43.5","Brain RNA - hypothalamus [nTPM]":"53.1","Brain RNA - medulla oblongata [nTPM]":"74.7","Brain RNA - midbrain [nTPM]":"55.5","Brain RNA - pons [nTPM]":"82.2","Brain RNA - spinal cord [nTPM]":"65.4","Brain RNA - thalamus [nTPM]":"57.0","Brain RNA - white matter [nTPM]":"115.5","Single Cell Type RNA - Adipocytes [nTPM]":"75.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.8","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"35.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"58.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"31.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.8","Single Cell Type RNA - dendritic cells [nTPM]":"31.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"35.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.4","Single Cell Type RNA - Endothelial cells [nTPM]":"56.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.8","Single Cell Type RNA - Erythroid cells [nTPM]":"27.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.9","Single Cell Type RNA - Fibroblasts [nTPM]":"34.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.5","Single Cell Type RNA - granulocytes [nTPM]":"28.5","Single Cell Type RNA - Granulosa cells [nTPM]":"10.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"54.7","Single Cell Type RNA - Hepatocytes [nTPM]":"66.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"515.0","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.9","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"714.8","Single Cell Type RNA - Langerhans cells [nTPM]":"69.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"303.1","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"71.7","Single Cell Type RNA - Muller glia cells [nTPM]":"33.1","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"143.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.3","Single Cell Type RNA - Paneth cells [nTPM]":"12.0","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"15.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"161.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.0","Single Cell Type RNA - Spermatocytes [nTPM]":"5.1","Single Cell Type RNA - Spermatogonia [nTPM]":"13.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"33.1","Single Cell Type RNA - Theca cells [nTPM]":"17.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.1","Single Cell Type RNA - Urothelial cells [nTPM]":"24.0"},{"Gene":"MAN2B1","Gene synonym":["LAMAN","MANB"],"Ensembl":"ENSG00000104774","Gene description":"Mannosidase alpha class 2B member 1","Uniprot":["O00754"],"Chromosome":"19","Position":"12646511-12666742","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Macrophages":"32.8","Plasma cells":"78.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"201.8","intermediate monocyte":"178.8","myeloid DC":"158.8","non-classical monocyte":"138.4","plasmacytoid DC":"187.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"187.5","monocytes":"201.8"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041530","HPA053404"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3200000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041530":"AB_10795639","HPA053404":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Tissue RNA - adipose tissue [nTPM]":"35.8","Tissue RNA - adrenal gland [nTPM]":"21.4","Tissue RNA - amygdala [nTPM]":"5.3","Tissue RNA - appendix [nTPM]":"54.6","Tissue RNA - basal ganglia [nTPM]":"6.4","Tissue RNA - bone marrow [nTPM]":"83.6","Tissue RNA - breast [nTPM]":"24.8","Tissue RNA - cerebellum [nTPM]":"6.6","Tissue RNA - cerebral cortex [nTPM]":"5.9","Tissue RNA - cervix [nTPM]":"19.6","Tissue RNA - choroid plexus [nTPM]":"18.5","Tissue RNA - colon [nTPM]":"30.3","Tissue RNA - duodenum [nTPM]":"31.0","Tissue RNA - endometrium 1 [nTPM]":"21.8","Tissue RNA - epididymis [nTPM]":"9.0","Tissue RNA - esophagus [nTPM]":"19.8","Tissue RNA - fallopian tube [nTPM]":"19.9","Tissue RNA - gallbladder [nTPM]":"28.4","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"7.4","Tissue RNA - kidney [nTPM]":"17.3","Tissue RNA - liver [nTPM]":"23.7","Tissue RNA - lung [nTPM]":"46.8","Tissue RNA - lymph node [nTPM]":"52.1","Tissue RNA - medulla oblongata [nTPM]":"10.3","Tissue RNA - midbrain [nTPM]":"6.7","Tissue RNA - ovary [nTPM]":"16.7","Tissue RNA - pancreas [nTPM]":"39.7","Tissue RNA - parathyroid gland [nTPM]":"16.6","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"24.6","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"20.5","Tissue RNA - rectum [nTPM]":"22.6","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"35.2","Tissue RNA - seminal vesicle [nTPM]":"14.9","Tissue RNA - skeletal muscle [nTPM]":"12.1","Tissue RNA - skin 1 [nTPM]":"28.9","Tissue RNA - small intestine [nTPM]":"33.6","Tissue RNA - smooth muscle [nTPM]":"20.2","Tissue RNA - spinal cord [nTPM]":"8.9","Tissue RNA - spleen [nTPM]":"70.1","Tissue RNA - stomach 1 [nTPM]":"32.7","Tissue RNA - testis [nTPM]":"6.4","Tissue RNA - thalamus [nTPM]":"9.7","Tissue RNA - thymus [nTPM]":"23.1","Tissue RNA - thyroid gland [nTPM]":"16.3","Tissue RNA - tongue [nTPM]":"9.4","Tissue RNA - tonsil [nTPM]":"39.3","Tissue RNA - urinary bladder [nTPM]":"35.6","Tissue RNA - vagina [nTPM]":"16.7","Tissue RNA - white matter [nTPM]":"12.4","Cell RNA - A-431 [nTPM]":"52.4","Cell RNA - A549 [nTPM]":"26.3","Cell RNA - AF22 [nTPM]":"26.4","Cell RNA - AN3-CA [nTPM]":"31.3","Cell RNA - ASC diff [nTPM]":"85.8","Cell RNA - ASC TERT1 [nTPM]":"57.3","Cell RNA - BEWO [nTPM]":"74.0","Cell RNA - BJ [nTPM]":"37.9","Cell RNA - BJ hTERT+ [nTPM]":"79.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.4","Cell RNA - CACO-2 [nTPM]":"21.3","Cell RNA - CAPAN-2 [nTPM]":"21.4","Cell RNA - Daudi [nTPM]":"56.9","Cell RNA - EFO-21 [nTPM]":"44.9","Cell RNA - fHDF\/TERT166 [nTPM]":"30.4","Cell RNA - GAMG [nTPM]":"9.4","Cell RNA - HaCaT [nTPM]":"40.1","Cell RNA - HAP1 [nTPM]":"13.6","Cell RNA - HBEC3-KT [nTPM]":"25.6","Cell RNA - HBF TERT88 [nTPM]":"15.7","Cell RNA - HDLM-2 [nTPM]":"28.5","Cell RNA - HEK 293 [nTPM]":"41.6","Cell RNA - HEL [nTPM]":"19.8","Cell RNA - HeLa [nTPM]":"13.6","Cell RNA - Hep G2 [nTPM]":"34.9","Cell RNA - HHSteC [nTPM]":"43.5","Cell RNA - HL-60 [nTPM]":"131.6","Cell RNA - HMC-1 [nTPM]":"130.2","Cell RNA - HSkMC [nTPM]":"68.5","Cell RNA - hTCEpi [nTPM]":"49.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.5","Cell RNA - hTERT-HME1 [nTPM]":"23.3","Cell RNA - hTERT-RPE1 [nTPM]":"35.6","Cell RNA - HUVEC TERT2 [nTPM]":"31.7","Cell RNA - JURKAT [nTPM]":"21.1","Cell RNA - K-562 [nTPM]":"25.6","Cell RNA - Karpas-707 [nTPM]":"41.9","Cell RNA - LHCN-M2 [nTPM]":"17.8","Cell RNA - MCF7 [nTPM]":"40.9","Cell RNA - MOLT-4 [nTPM]":"17.9","Cell RNA - NB-4 [nTPM]":"74.2","Cell RNA - NTERA-2 [nTPM]":"21.9","Cell RNA - OE19 [nTPM]":"26.2","Cell RNA - PC-3 [nTPM]":"32.8","Cell RNA - REH [nTPM]":"40.8","Cell RNA - RH-30 [nTPM]":"36.1","Cell RNA - RPMI-8226 [nTPM]":"28.8","Cell RNA - RPTEC TERT1 [nTPM]":"38.9","Cell RNA - RT4 [nTPM]":"59.8","Cell RNA - SCLC-21H [nTPM]":"8.2","Cell RNA - SH-SY5Y [nTPM]":"25.5","Cell RNA - SiHa [nTPM]":"37.7","Cell RNA - SK-BR-3 [nTPM]":"32.0","Cell RNA - SK-MEL-30 [nTPM]":"63.0","Cell RNA - SuSa [nTPM]":"15.8","Cell RNA - T-47d [nTPM]":"49.4","Cell RNA - THP-1 [nTPM]":"80.0","Cell RNA - TIME [nTPM]":"42.0","Cell RNA - U-138 MG [nTPM]":"44.8","Cell RNA - U-2 OS [nTPM]":"18.4","Cell RNA - U-2197 [nTPM]":"44.0","Cell RNA - U-251 MG [nTPM]":"36.2","Cell RNA - U-266\/70 [nTPM]":"55.4","Cell RNA - U-266\/84 [nTPM]":"65.5","Cell RNA - U-698 [nTPM]":"28.0","Cell RNA - U-87 MG [nTPM]":"30.4","Cell RNA - U-937 [nTPM]":"127.5","Cell RNA - WM-115 [nTPM]":"51.2","Blood RNA - basophil [nTPM]":"12.2","Blood RNA - classical monocyte [nTPM]":"201.8","Blood RNA - eosinophil [nTPM]":"29.7","Blood RNA - gdT-cell [nTPM]":"31.9","Blood RNA - intermediate monocyte [nTPM]":"178.8","Blood RNA - MAIT T-cell [nTPM]":"35.4","Blood RNA - memory B-cell [nTPM]":"32.9","Blood RNA - memory CD4 T-cell [nTPM]":"28.9","Blood RNA - memory CD8 T-cell [nTPM]":"29.0","Blood RNA - myeloid DC [nTPM]":"158.8","Blood RNA - naive B-cell [nTPM]":"26.4","Blood RNA - naive CD4 T-cell [nTPM]":"15.4","Blood RNA - naive CD8 T-cell [nTPM]":"15.9","Blood RNA - neutrophil [nTPM]":"29.4","Blood RNA - NK-cell [nTPM]":"13.2","Blood RNA - non-classical monocyte [nTPM]":"138.4","Blood RNA - plasmacytoid DC [nTPM]":"187.5","Blood RNA - T-reg [nTPM]":"30.7","Blood RNA - total PBMC [nTPM]":"150.3","Brain RNA - amygdala [nTPM]":"5.3","Brain RNA - basal ganglia [nTPM]":"6.4","Brain RNA - cerebellum [nTPM]":"6.6","Brain RNA - cerebral cortex [nTPM]":"5.9","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"7.4","Brain RNA - medulla oblongata [nTPM]":"10.3","Brain RNA - midbrain [nTPM]":"6.7","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"8.9","Brain RNA - thalamus [nTPM]":"9.7","Brain RNA - white matter [nTPM]":"12.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"25.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - dendritic cells [nTPM]":"20.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.5","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"7.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"3.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"15.4","Single Cell Type RNA - Langerhans cells [nTPM]":"24.7","Single Cell Type RNA - Late spermatids [nTPM]":"11.1","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"32.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"11.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"78.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - T-cells [nTPM]":"9.4","Single Cell Type RNA - Theca cells [nTPM]":"2.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.0"},{"Gene":"MANBA","Gene synonym":[],"Ensembl":"ENSG00000109323","Gene description":"Mannosidase beta","Uniprot":["O00462"],"Chromosome":"4","Position":"102630770-102760994","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Macrophages":"74.0","Microglial cells":"111.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"16.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"5.3","granulocytes":"16.6","monocytes":"9.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"15.5","hTCEpi":"13.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053478"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA053478":"AB_2682165"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.56e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.74e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.1","Tissue RNA - adrenal gland [nTPM]":"12.4","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"7.0","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"2.2","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"6.1","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"6.3","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"10.5","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"8.8","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"5.0","Tissue RNA - placenta [nTPM]":"3.7","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"4.3","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"8.9","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"4.5","Tissue RNA - small intestine [nTPM]":"8.5","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"9.1","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"7.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"8.1","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"2.9","Cell RNA - A549 [nTPM]":"1.4","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"1.6","Cell RNA - ASC diff [nTPM]":"15.5","Cell RNA - ASC TERT1 [nTPM]":"12.1","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"1.1","Cell RNA - BJ hTERT+ [nTPM]":"6.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"3.6","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"2.7","Cell RNA - GAMG [nTPM]":"3.9","Cell RNA - HaCaT [nTPM]":"1.0","Cell RNA - HAP1 [nTPM]":"3.0","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"2.2","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"3.0","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"2.8","Cell RNA - HMC-1 [nTPM]":"8.2","Cell RNA - HSkMC [nTPM]":"3.7","Cell RNA - hTCEpi [nTPM]":"13.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.6","Cell RNA - hTERT-HME1 [nTPM]":"3.4","Cell RNA - hTERT-RPE1 [nTPM]":"8.9","Cell RNA - HUVEC TERT2 [nTPM]":"3.0","Cell RNA - JURKAT [nTPM]":"1.2","Cell RNA - K-562 [nTPM]":"3.6","Cell RNA - Karpas-707 [nTPM]":"2.0","Cell RNA - LHCN-M2 [nTPM]":"3.4","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"2.3","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"1.9","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"1.9","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"3.4","Cell RNA - RT4 [nTPM]":"2.3","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"1.4","Cell RNA - SK-BR-3 [nTPM]":"1.9","Cell RNA - SK-MEL-30 [nTPM]":"1.5","Cell RNA - SuSa [nTPM]":"5.4","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"1.8","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"2.0","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"9.3","Cell RNA - U-251 MG [nTPM]":"1.2","Cell RNA - U-266\/70 [nTPM]":"1.3","Cell RNA - U-266\/84 [nTPM]":"5.8","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"3.1","Cell RNA - U-937 [nTPM]":"1.5","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"4.0","Blood RNA - classical monocyte [nTPM]":"6.8","Blood RNA - eosinophil [nTPM]":"16.6","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"6.1","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"5.3","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"6.1","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"9.1","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"2.2","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"35.6","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"45.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"13.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.3","Single Cell Type RNA - dendritic cells [nTPM]":"14.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.9","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"19.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.3","Single Cell Type RNA - Fibroblasts [nTPM]":"13.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"34.8","Single Cell Type RNA - Granulosa cells [nTPM]":"5.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"17.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"43.6","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"66.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"58.5","Single Cell Type RNA - Langerhans cells [nTPM]":"29.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"74.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"111.5","Single Cell Type RNA - monocytes [nTPM]":"52.8","Single Cell Type RNA - Muller glia cells [nTPM]":"5.2","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"66.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.5","Single Cell Type RNA - Paneth cells [nTPM]":"17.3","Single Cell Type RNA - Peritubular cells [nTPM]":"19.9","Single Cell Type RNA - Plasma cells [nTPM]":"17.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.6","Single Cell Type RNA - T-cells [nTPM]":"16.9","Single Cell Type RNA - Theca cells [nTPM]":"12.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.2","Single Cell Type RNA - Urothelial cells [nTPM]":"9.7"},{"Gene":"MCOLN1","Gene synonym":["ML4","MLIV","MST080","MSTP080","TRPM-L1","TRPML1"],"Ensembl":"ENSG00000090674","Gene description":"Mucolipin 1","Uniprot":["Q9GZU1"],"Chromosome":"19","Position":"7522624-7534009","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Adaptive immunity","Calcium transport","Immunity","Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant","Mucolipidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"109.4","Kupffer cells":"117.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"117.5","classical monocyte":"45.2","eosinophil":"105.7","intermediate monocyte":"95.5","neutrophil":"41.1","non-classical monocyte":"105.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"117.5","monocytes":"105.1"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031763","CAB032637","HPA069495"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB032637":"AB_2142964","HPA031763":"AB_10600822","HPA069495":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.60e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.67e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.2","Tissue RNA - adrenal gland [nTPM]":"37.4","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"10.4","Tissue RNA - breast [nTPM]":"15.3","Tissue RNA - cerebellum [nTPM]":"7.0","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"11.7","Tissue RNA - choroid plexus [nTPM]":"8.3","Tissue RNA - colon [nTPM]":"13.6","Tissue RNA - duodenum [nTPM]":"8.3","Tissue RNA - endometrium 1 [nTPM]":"11.6","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"12.2","Tissue RNA - gallbladder [nTPM]":"10.1","Tissue RNA - heart muscle [nTPM]":"15.7","Tissue RNA - hippocampal formation [nTPM]":"7.0","Tissue RNA - hypothalamus [nTPM]":"7.4","Tissue RNA - kidney [nTPM]":"11.7","Tissue RNA - liver [nTPM]":"14.7","Tissue RNA - lung [nTPM]":"20.3","Tissue RNA - lymph node [nTPM]":"13.2","Tissue RNA - medulla oblongata [nTPM]":"8.2","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"10.0","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"10.2","Tissue RNA - pituitary gland [nTPM]":"21.7","Tissue RNA - placenta [nTPM]":"15.9","Tissue RNA - pons [nTPM]":"9.0","Tissue RNA - prostate [nTPM]":"8.7","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"5.0","Tissue RNA - salivary gland [nTPM]":"12.3","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"22.2","Tissue RNA - skin 1 [nTPM]":"20.8","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"48.2","Tissue RNA - stomach 1 [nTPM]":"12.8","Tissue RNA - testis [nTPM]":"5.6","Tissue RNA - thalamus [nTPM]":"8.2","Tissue RNA - thymus [nTPM]":"6.2","Tissue RNA - thyroid gland [nTPM]":"8.5","Tissue RNA - tongue [nTPM]":"11.7","Tissue RNA - tonsil [nTPM]":"4.1","Tissue RNA - urinary bladder [nTPM]":"15.8","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"11.6","Cell RNA - A549 [nTPM]":"11.7","Cell RNA - AF22 [nTPM]":"5.6","Cell RNA - AN3-CA [nTPM]":"19.1","Cell RNA - ASC diff [nTPM]":"32.0","Cell RNA - ASC TERT1 [nTPM]":"10.3","Cell RNA - BEWO [nTPM]":"16.1","Cell RNA - BJ [nTPM]":"21.2","Cell RNA - BJ hTERT+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.6","Cell RNA - CACO-2 [nTPM]":"9.0","Cell RNA - CAPAN-2 [nTPM]":"10.0","Cell RNA - Daudi [nTPM]":"6.5","Cell RNA - EFO-21 [nTPM]":"25.5","Cell RNA - fHDF\/TERT166 [nTPM]":"14.5","Cell RNA - GAMG [nTPM]":"22.2","Cell RNA - HaCaT [nTPM]":"5.3","Cell RNA - HAP1 [nTPM]":"9.5","Cell RNA - HBEC3-KT [nTPM]":"7.3","Cell RNA - HBF TERT88 [nTPM]":"7.4","Cell RNA - HDLM-2 [nTPM]":"12.7","Cell RNA - HEK 293 [nTPM]":"21.1","Cell RNA - HEL [nTPM]":"5.8","Cell RNA - HeLa [nTPM]":"11.0","Cell RNA - Hep G2 [nTPM]":"7.3","Cell RNA - HHSteC [nTPM]":"28.0","Cell RNA - HL-60 [nTPM]":"6.6","Cell RNA - HMC-1 [nTPM]":"24.5","Cell RNA - HSkMC [nTPM]":"14.5","Cell RNA - hTCEpi [nTPM]":"16.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.1","Cell RNA - hTERT-HME1 [nTPM]":"4.2","Cell RNA - hTERT-RPE1 [nTPM]":"7.9","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"14.2","Cell RNA - K-562 [nTPM]":"10.9","Cell RNA - Karpas-707 [nTPM]":"27.9","Cell RNA - LHCN-M2 [nTPM]":"14.7","Cell RNA - MCF7 [nTPM]":"3.9","Cell RNA - MOLT-4 [nTPM]":"9.1","Cell RNA - NB-4 [nTPM]":"6.6","Cell RNA - NTERA-2 [nTPM]":"12.6","Cell RNA - OE19 [nTPM]":"6.1","Cell RNA - PC-3 [nTPM]":"24.8","Cell RNA - REH [nTPM]":"12.6","Cell RNA - RH-30 [nTPM]":"9.4","Cell RNA - RPMI-8226 [nTPM]":"13.8","Cell RNA - RPTEC TERT1 [nTPM]":"9.6","Cell RNA - RT4 [nTPM]":"9.9","Cell RNA - SCLC-21H [nTPM]":"14.4","Cell RNA - SH-SY5Y [nTPM]":"17.8","Cell RNA - SiHa [nTPM]":"9.1","Cell RNA - SK-BR-3 [nTPM]":"15.8","Cell RNA - SK-MEL-30 [nTPM]":"26.8","Cell RNA - SuSa [nTPM]":"6.1","Cell RNA - T-47d [nTPM]":"9.6","Cell RNA - THP-1 [nTPM]":"11.4","Cell RNA - TIME [nTPM]":"13.5","Cell RNA - U-138 MG [nTPM]":"12.0","Cell RNA - U-2 OS [nTPM]":"6.9","Cell RNA - U-2197 [nTPM]":"48.8","Cell RNA - U-251 MG [nTPM]":"16.0","Cell RNA - U-266\/70 [nTPM]":"21.5","Cell RNA - U-266\/84 [nTPM]":"35.5","Cell RNA - U-698 [nTPM]":"4.7","Cell RNA - U-87 MG [nTPM]":"19.2","Cell RNA - U-937 [nTPM]":"9.2","Cell RNA - WM-115 [nTPM]":"18.4","Blood RNA - basophil [nTPM]":"117.5","Blood RNA - classical monocyte [nTPM]":"45.2","Blood RNA - eosinophil [nTPM]":"105.7","Blood RNA - gdT-cell [nTPM]":"7.7","Blood RNA - intermediate monocyte [nTPM]":"95.5","Blood RNA - MAIT T-cell [nTPM]":"6.3","Blood RNA - memory B-cell [nTPM]":"4.2","Blood RNA - memory CD4 T-cell [nTPM]":"6.5","Blood RNA - memory CD8 T-cell [nTPM]":"6.3","Blood RNA - myeloid DC [nTPM]":"19.2","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"6.0","Blood RNA - naive CD8 T-cell [nTPM]":"6.5","Blood RNA - neutrophil [nTPM]":"41.1","Blood RNA - NK-cell [nTPM]":"10.3","Blood RNA - non-classical monocyte [nTPM]":"105.1","Blood RNA - plasmacytoid DC [nTPM]":"21.1","Blood RNA - T-reg [nTPM]":"10.0","Blood RNA - total PBMC [nTPM]":"17.1","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"7.0","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"7.0","Brain RNA - hypothalamus [nTPM]":"7.4","Brain RNA - medulla oblongata [nTPM]":"8.2","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"9.0","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"8.2","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"15.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"8.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"27.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.6","Single Cell Type RNA - dendritic cells [nTPM]":"12.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"23.7","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.8","Single Cell Type RNA - Endothelial cells [nTPM]":"14.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.0","Single Cell Type RNA - Fibroblasts [nTPM]":"16.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"22.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"13.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"109.4","Single Cell Type RNA - Horizontal cells [nTPM]":"58.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"117.1","Single Cell Type RNA - Langerhans cells [nTPM]":"32.2","Single Cell Type RNA - Late spermatids [nTPM]":"17.0","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"70.6","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"18.0","Single Cell Type RNA - Muller glia cells [nTPM]":"23.0","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.4","Single Cell Type RNA - Paneth cells [nTPM]":"19.3","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.8","Single Cell Type RNA - Spermatocytes [nTPM]":"10.3","Single Cell Type RNA - Spermatogonia [nTPM]":"14.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.6","Single Cell Type RNA - T-cells [nTPM]":"8.7","Single Cell Type RNA - Theca cells [nTPM]":"17.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.4","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"MFSD8","Gene synonym":["CLN7","MGC33302"],"Ensembl":"ENSG00000164073","Gene description":"Major facilitator superfamily domain containing 8","Uniprot":["Q8NHS3"],"Chromosome":"4","Position":"127917799-127966034","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044802"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA044802":"AB_10963221"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.21e-4"},"Tissue RNA - adipose tissue [nTPM]":"4.6","Tissue RNA - adrenal gland [nTPM]":"5.7","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"6.9","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"6.2","Tissue RNA - choroid plexus [nTPM]":"1.1","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"10.0","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"10.0","Tissue RNA - lung [nTPM]":"4.8","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"6.8","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"9.1","Tissue RNA - pituitary gland [nTPM]":"7.1","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"4.4","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"7.6","Tissue RNA - smooth muscle [nTPM]":"5.8","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"7.3","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"7.0","Tissue RNA - tongue [nTPM]":"4.4","Tissue RNA - tonsil [nTPM]":"7.9","Tissue RNA - urinary bladder [nTPM]":"5.3","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"10.9","Cell RNA - A549 [nTPM]":"7.3","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"4.6","Cell RNA - ASC diff [nTPM]":"7.2","Cell RNA - ASC TERT1 [nTPM]":"6.9","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"8.3","Cell RNA - BJ hTERT+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.5","Cell RNA - CACO-2 [nTPM]":"5.2","Cell RNA - CAPAN-2 [nTPM]":"14.3","Cell RNA - Daudi [nTPM]":"5.2","Cell RNA - EFO-21 [nTPM]":"14.5","Cell RNA - fHDF\/TERT166 [nTPM]":"14.3","Cell RNA - GAMG [nTPM]":"14.8","Cell RNA - HaCaT [nTPM]":"7.8","Cell RNA - HAP1 [nTPM]":"10.2","Cell RNA - HBEC3-KT [nTPM]":"7.4","Cell RNA - HBF TERT88 [nTPM]":"14.4","Cell RNA - HDLM-2 [nTPM]":"10.8","Cell RNA - HEK 293 [nTPM]":"7.9","Cell RNA - HEL [nTPM]":"5.7","Cell RNA - HeLa [nTPM]":"9.1","Cell RNA - Hep G2 [nTPM]":"8.0","Cell RNA - HHSteC [nTPM]":"9.4","Cell RNA - HL-60 [nTPM]":"6.0","Cell RNA - HMC-1 [nTPM]":"6.6","Cell RNA - HSkMC [nTPM]":"8.3","Cell RNA - hTCEpi [nTPM]":"2.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.6","Cell RNA - hTERT-HME1 [nTPM]":"7.7","Cell RNA - hTERT-RPE1 [nTPM]":"5.0","Cell RNA - HUVEC TERT2 [nTPM]":"10.6","Cell RNA - JURKAT [nTPM]":"6.6","Cell RNA - K-562 [nTPM]":"9.5","Cell RNA - Karpas-707 [nTPM]":"5.9","Cell RNA - LHCN-M2 [nTPM]":"14.6","Cell RNA - MCF7 [nTPM]":"8.9","Cell RNA - MOLT-4 [nTPM]":"5.0","Cell RNA - NB-4 [nTPM]":"1.9","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"11.8","Cell RNA - PC-3 [nTPM]":"5.2","Cell RNA - REH [nTPM]":"5.3","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"4.7","Cell RNA - RPTEC TERT1 [nTPM]":"7.5","Cell RNA - RT4 [nTPM]":"13.9","Cell RNA - SCLC-21H [nTPM]":"8.5","Cell RNA - SH-SY5Y [nTPM]":"2.9","Cell RNA - SiHa [nTPM]":"9.0","Cell RNA - SK-BR-3 [nTPM]":"12.0","Cell RNA - SK-MEL-30 [nTPM]":"3.5","Cell RNA - SuSa [nTPM]":"6.4","Cell RNA - T-47d [nTPM]":"5.6","Cell RNA - THP-1 [nTPM]":"5.1","Cell RNA - TIME [nTPM]":"6.7","Cell RNA - U-138 MG [nTPM]":"2.9","Cell RNA - U-2 OS [nTPM]":"3.1","Cell RNA - U-2197 [nTPM]":"10.7","Cell RNA - U-251 MG [nTPM]":"7.8","Cell RNA - U-266\/70 [nTPM]":"12.5","Cell RNA - U-266\/84 [nTPM]":"22.1","Cell RNA - U-698 [nTPM]":"9.6","Cell RNA - U-87 MG [nTPM]":"10.3","Cell RNA - U-937 [nTPM]":"5.3","Cell RNA - WM-115 [nTPM]":"8.8","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"3.7","Blood RNA - plasmacytoid DC [nTPM]":"2.2","Blood RNA - T-reg [nTPM]":"3.4","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"9.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.1","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"18.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"17.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"14.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.5","Single Cell Type RNA - dendritic cells [nTPM]":"17.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.5","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"7.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.3","Single Cell Type RNA - Fibroblasts [nTPM]":"8.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.2","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"18.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"10.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.6","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.5","Single Cell Type RNA - Langerhans cells [nTPM]":"3.3","Single Cell Type RNA - Late spermatids [nTPM]":"14.7","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"6.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"10.5","Single Cell Type RNA - Muller glia cells [nTPM]":"8.6","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.8","Single Cell Type RNA - Paneth cells [nTPM]":"9.5","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"19.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"12.6","Single Cell Type RNA - Spermatogonia [nTPM]":"8.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.0","Single Cell Type RNA - T-cells [nTPM]":"13.7","Single Cell Type RNA - Theca cells [nTPM]":"11.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"NAGA","Gene synonym":["D22S674"],"Ensembl":"ENSG00000198951","Gene description":"Alpha-N-acetylgalactosaminidase","Uniprot":["P17050"],"Chromosome":"22","Position":"42058334-42070842","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"65.0","Hofbauer cells":"91.6","Kupffer cells":"64.4","monocytes":"65.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"202.5","intermediate monocyte":"249.1","myeloid DC":"195.2","non-classical monocyte":"257.9","plasmacytoid DC":"119.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"195.2","monocytes":"257.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"190.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000649"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2200000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000649":"AB_1079448"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.4","Tissue RNA - adrenal gland [nTPM]":"12.7","Tissue RNA - amygdala [nTPM]":"9.3","Tissue RNA - appendix [nTPM]":"32.3","Tissue RNA - basal ganglia [nTPM]":"10.4","Tissue RNA - bone marrow [nTPM]":"20.1","Tissue RNA - breast [nTPM]":"13.4","Tissue RNA - cerebellum [nTPM]":"10.3","Tissue RNA - cerebral cortex [nTPM]":"10.1","Tissue RNA - cervix [nTPM]":"20.6","Tissue RNA - choroid plexus [nTPM]":"17.0","Tissue RNA - colon [nTPM]":"26.1","Tissue RNA - duodenum [nTPM]":"20.4","Tissue RNA - endometrium 1 [nTPM]":"17.2","Tissue RNA - epididymis [nTPM]":"12.4","Tissue RNA - esophagus [nTPM]":"17.2","Tissue RNA - fallopian tube [nTPM]":"20.0","Tissue RNA - gallbladder [nTPM]":"22.1","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"14.9","Tissue RNA - liver [nTPM]":"31.9","Tissue RNA - lung [nTPM]":"27.1","Tissue RNA - lymph node [nTPM]":"20.8","Tissue RNA - medulla oblongata [nTPM]":"13.9","Tissue RNA - midbrain [nTPM]":"10.8","Tissue RNA - ovary [nTPM]":"17.0","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"39.2","Tissue RNA - pituitary gland [nTPM]":"11.7","Tissue RNA - placenta [nTPM]":"42.8","Tissue RNA - pons [nTPM]":"12.6","Tissue RNA - prostate [nTPM]":"18.2","Tissue RNA - rectum [nTPM]":"26.7","Tissue RNA - retina [nTPM]":"7.7","Tissue RNA - salivary gland [nTPM]":"17.3","Tissue RNA - seminal vesicle [nTPM]":"18.6","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"24.2","Tissue RNA - smooth muscle [nTPM]":"28.3","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"20.3","Tissue RNA - stomach 1 [nTPM]":"16.6","Tissue RNA - testis [nTPM]":"9.0","Tissue RNA - thalamus [nTPM]":"12.0","Tissue RNA - thymus [nTPM]":"13.9","Tissue RNA - thyroid gland [nTPM]":"15.1","Tissue RNA - tongue [nTPM]":"12.3","Tissue RNA - tonsil [nTPM]":"19.0","Tissue RNA - urinary bladder [nTPM]":"24.8","Tissue RNA - vagina [nTPM]":"13.7","Tissue RNA - white matter [nTPM]":"14.4","Cell RNA - A-431 [nTPM]":"27.8","Cell RNA - A549 [nTPM]":"14.0","Cell RNA - AF22 [nTPM]":"21.7","Cell RNA - AN3-CA [nTPM]":"38.9","Cell RNA - ASC diff [nTPM]":"37.0","Cell RNA - ASC TERT1 [nTPM]":"41.9","Cell RNA - BEWO [nTPM]":"15.9","Cell RNA - BJ [nTPM]":"22.4","Cell RNA - BJ hTERT+ [nTPM]":"45.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"37.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.2","Cell RNA - CACO-2 [nTPM]":"31.4","Cell RNA - CAPAN-2 [nTPM]":"39.9","Cell RNA - Daudi [nTPM]":"13.5","Cell RNA - EFO-21 [nTPM]":"13.5","Cell RNA - fHDF\/TERT166 [nTPM]":"49.1","Cell RNA - GAMG [nTPM]":"22.9","Cell RNA - HaCaT [nTPM]":"19.2","Cell RNA - HAP1 [nTPM]":"16.7","Cell RNA - HBEC3-KT [nTPM]":"27.4","Cell RNA - HBF TERT88 [nTPM]":"22.3","Cell RNA - HDLM-2 [nTPM]":"31.0","Cell RNA - HEK 293 [nTPM]":"21.2","Cell RNA - HEL [nTPM]":"33.5","Cell RNA - HeLa [nTPM]":"20.1","Cell RNA - Hep G2 [nTPM]":"21.5","Cell RNA - HHSteC [nTPM]":"21.5","Cell RNA - HL-60 [nTPM]":"28.1","Cell RNA - HMC-1 [nTPM]":"190.4","Cell RNA - HSkMC [nTPM]":"28.9","Cell RNA - hTCEpi [nTPM]":"23.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.0","Cell RNA - hTERT-HME1 [nTPM]":"14.4","Cell RNA - hTERT-RPE1 [nTPM]":"19.5","Cell RNA - HUVEC TERT2 [nTPM]":"63.4","Cell RNA - JURKAT [nTPM]":"11.6","Cell RNA - K-562 [nTPM]":"12.4","Cell RNA - Karpas-707 [nTPM]":"56.0","Cell RNA - LHCN-M2 [nTPM]":"30.2","Cell RNA - MCF7 [nTPM]":"32.3","Cell RNA - MOLT-4 [nTPM]":"10.4","Cell RNA - NB-4 [nTPM]":"11.5","Cell RNA - NTERA-2 [nTPM]":"5.8","Cell RNA - OE19 [nTPM]":"25.3","Cell RNA - PC-3 [nTPM]":"18.5","Cell RNA - REH [nTPM]":"23.0","Cell RNA - RH-30 [nTPM]":"11.0","Cell RNA - RPMI-8226 [nTPM]":"24.2","Cell RNA - RPTEC TERT1 [nTPM]":"29.4","Cell RNA - RT4 [nTPM]":"32.7","Cell RNA - SCLC-21H [nTPM]":"6.7","Cell RNA - SH-SY5Y [nTPM]":"7.7","Cell RNA - SiHa [nTPM]":"29.8","Cell RNA - SK-BR-3 [nTPM]":"27.0","Cell RNA - SK-MEL-30 [nTPM]":"29.3","Cell RNA - SuSa [nTPM]":"19.1","Cell RNA - T-47d [nTPM]":"40.4","Cell RNA - THP-1 [nTPM]":"50.9","Cell RNA - TIME [nTPM]":"34.4","Cell RNA - U-138 MG [nTPM]":"26.6","Cell RNA - U-2 OS [nTPM]":"31.8","Cell RNA - U-2197 [nTPM]":"17.1","Cell RNA - U-251 MG [nTPM]":"20.7","Cell RNA - U-266\/70 [nTPM]":"30.9","Cell RNA - U-266\/84 [nTPM]":"33.3","Cell RNA - U-698 [nTPM]":"10.9","Cell RNA - U-87 MG [nTPM]":"28.3","Cell RNA - U-937 [nTPM]":"52.7","Cell RNA - WM-115 [nTPM]":"33.4","Blood RNA - basophil [nTPM]":"36.5","Blood RNA - classical monocyte [nTPM]":"202.5","Blood RNA - eosinophil [nTPM]":"25.1","Blood RNA - gdT-cell [nTPM]":"13.6","Blood RNA - intermediate monocyte [nTPM]":"249.1","Blood RNA - MAIT T-cell [nTPM]":"13.8","Blood RNA - memory B-cell [nTPM]":"10.5","Blood RNA - memory CD4 T-cell [nTPM]":"14.1","Blood RNA - memory CD8 T-cell [nTPM]":"12.7","Blood RNA - myeloid DC [nTPM]":"195.2","Blood RNA - naive B-cell [nTPM]":"6.9","Blood RNA - naive CD4 T-cell [nTPM]":"9.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.4","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"18.8","Blood RNA - non-classical monocyte [nTPM]":"257.9","Blood RNA - plasmacytoid DC [nTPM]":"119.8","Blood RNA - T-reg [nTPM]":"18.3","Blood RNA - total PBMC [nTPM]":"121.0","Brain RNA - amygdala [nTPM]":"9.3","Brain RNA - basal ganglia [nTPM]":"10.4","Brain RNA - cerebellum [nTPM]":"10.3","Brain RNA - cerebral cortex [nTPM]":"10.1","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"13.9","Brain RNA - midbrain [nTPM]":"10.8","Brain RNA - pons [nTPM]":"12.6","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"12.0","Brain RNA - white matter [nTPM]":"14.4","Single Cell Type RNA - Adipocytes [nTPM]":"6.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"2.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"11.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.1","Single Cell Type RNA - dendritic cells [nTPM]":"11.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.4","Single Cell Type RNA - Early spermatids [nTPM]":"15.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.8","Single Cell Type RNA - Endothelial cells [nTPM]":"11.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"65.0","Single Cell Type RNA - Fibroblasts [nTPM]":"13.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.2","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"3.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"33.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"91.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"64.4","Single Cell Type RNA - Langerhans cells [nTPM]":"36.3","Single Cell Type RNA - Late spermatids [nTPM]":"17.9","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"52.5","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"65.8","Single Cell Type RNA - Muller glia cells [nTPM]":"5.9","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.0","Single Cell Type RNA - Paneth cells [nTPM]":"23.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"22.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"40.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.0","Single Cell Type RNA - Spermatocytes [nTPM]":"10.7","Single Cell Type RNA - Spermatogonia [nTPM]":"5.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"58.3","Single Cell Type RNA - T-cells [nTPM]":"6.9","Single Cell Type RNA - Theca cells [nTPM]":"6.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.4","Single Cell Type RNA - Urothelial cells [nTPM]":"10.0"},{"Gene":"NAGLU","Gene synonym":["NAG"],"Ensembl":"ENSG00000108784","Gene description":"N-acetyl-alpha-glucosaminidase","Uniprot":["P54802"],"Chromosome":"17","Position":"42536241-42544449","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Mucopolysaccharidosis","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Theca cells":"74.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038815"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038815":"AB_10697398"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.59e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"41.6","Tissue RNA - adrenal gland [nTPM]":"37.9","Tissue RNA - amygdala [nTPM]":"12.5","Tissue RNA - appendix [nTPM]":"14.8","Tissue RNA - basal ganglia [nTPM]":"21.6","Tissue RNA - bone marrow [nTPM]":"20.3","Tissue RNA - breast [nTPM]":"35.3","Tissue RNA - cerebellum [nTPM]":"16.6","Tissue RNA - cerebral cortex [nTPM]":"16.7","Tissue RNA - cervix [nTPM]":"31.1","Tissue RNA - choroid plexus [nTPM]":"28.7","Tissue RNA - colon [nTPM]":"25.1","Tissue RNA - duodenum [nTPM]":"24.3","Tissue RNA - endometrium 1 [nTPM]":"34.7","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"19.5","Tissue RNA - fallopian tube [nTPM]":"27.6","Tissue RNA - gallbladder [nTPM]":"27.4","Tissue RNA - heart muscle [nTPM]":"20.1","Tissue RNA - hippocampal formation [nTPM]":"12.0","Tissue RNA - hypothalamus [nTPM]":"15.0","Tissue RNA - kidney [nTPM]":"39.3","Tissue RNA - liver [nTPM]":"59.3","Tissue RNA - lung [nTPM]":"30.8","Tissue RNA - lymph node [nTPM]":"24.0","Tissue RNA - medulla oblongata [nTPM]":"18.0","Tissue RNA - midbrain [nTPM]":"19.2","Tissue RNA - ovary [nTPM]":"35.2","Tissue RNA - pancreas [nTPM]":"63.8","Tissue RNA - parathyroid gland [nTPM]":"21.3","Tissue RNA - pituitary gland [nTPM]":"22.5","Tissue RNA - placenta [nTPM]":"26.1","Tissue RNA - pons [nTPM]":"20.1","Tissue RNA - prostate [nTPM]":"28.3","Tissue RNA - rectum [nTPM]":"16.4","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"37.7","Tissue RNA - seminal vesicle [nTPM]":"18.4","Tissue RNA - skeletal muscle [nTPM]":"16.0","Tissue RNA - skin 1 [nTPM]":"25.1","Tissue RNA - small intestine [nTPM]":"30.9","Tissue RNA - smooth muscle [nTPM]":"13.8","Tissue RNA - spinal cord [nTPM]":"14.2","Tissue RNA - spleen [nTPM]":"40.7","Tissue RNA - stomach 1 [nTPM]":"35.1","Tissue RNA - testis [nTPM]":"8.7","Tissue RNA - thalamus [nTPM]":"19.5","Tissue RNA - thymus [nTPM]":"17.1","Tissue RNA - thyroid gland [nTPM]":"37.6","Tissue RNA - tongue [nTPM]":"9.7","Tissue RNA - tonsil [nTPM]":"13.4","Tissue RNA - urinary bladder [nTPM]":"28.9","Tissue RNA - vagina [nTPM]":"23.9","Tissue RNA - white matter [nTPM]":"30.0","Cell RNA - A-431 [nTPM]":"16.0","Cell RNA - A549 [nTPM]":"55.3","Cell RNA - AF22 [nTPM]":"10.8","Cell RNA - AN3-CA [nTPM]":"24.6","Cell RNA - ASC diff [nTPM]":"106.6","Cell RNA - ASC TERT1 [nTPM]":"34.5","Cell RNA - BEWO [nTPM]":"36.4","Cell RNA - BJ [nTPM]":"24.0","Cell RNA - BJ hTERT+ [nTPM]":"56.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.7","Cell RNA - CACO-2 [nTPM]":"14.9","Cell RNA - CAPAN-2 [nTPM]":"40.4","Cell RNA - Daudi [nTPM]":"20.3","Cell RNA - EFO-21 [nTPM]":"23.7","Cell RNA - fHDF\/TERT166 [nTPM]":"37.4","Cell RNA - GAMG [nTPM]":"54.7","Cell RNA - HaCaT [nTPM]":"38.3","Cell RNA - HAP1 [nTPM]":"9.7","Cell RNA - HBEC3-KT [nTPM]":"11.7","Cell RNA - HBF TERT88 [nTPM]":"5.5","Cell RNA - HDLM-2 [nTPM]":"15.8","Cell RNA - HEK 293 [nTPM]":"20.2","Cell RNA - HEL [nTPM]":"11.2","Cell RNA - HeLa [nTPM]":"31.3","Cell RNA - Hep G2 [nTPM]":"31.8","Cell RNA - HHSteC [nTPM]":"35.3","Cell RNA - HL-60 [nTPM]":"13.3","Cell RNA - HMC-1 [nTPM]":"27.7","Cell RNA - HSkMC [nTPM]":"41.4","Cell RNA - hTCEpi [nTPM]":"17.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.6","Cell RNA - hTERT-HME1 [nTPM]":"16.9","Cell RNA - hTERT-RPE1 [nTPM]":"27.3","Cell RNA - HUVEC TERT2 [nTPM]":"32.8","Cell RNA - JURKAT [nTPM]":"3.6","Cell RNA - K-562 [nTPM]":"16.6","Cell RNA - Karpas-707 [nTPM]":"39.3","Cell RNA - LHCN-M2 [nTPM]":"27.9","Cell RNA - MCF7 [nTPM]":"38.9","Cell RNA - MOLT-4 [nTPM]":"2.2","Cell RNA - NB-4 [nTPM]":"23.0","Cell RNA - NTERA-2 [nTPM]":"12.6","Cell RNA - OE19 [nTPM]":"34.6","Cell RNA - PC-3 [nTPM]":"7.0","Cell RNA - REH [nTPM]":"8.7","Cell RNA - RH-30 [nTPM]":"23.6","Cell RNA - RPMI-8226 [nTPM]":"47.2","Cell RNA - RPTEC TERT1 [nTPM]":"33.1","Cell RNA - RT4 [nTPM]":"36.1","Cell RNA - SCLC-21H [nTPM]":"16.2","Cell RNA - SH-SY5Y [nTPM]":"24.4","Cell RNA - SiHa [nTPM]":"12.9","Cell RNA - SK-BR-3 [nTPM]":"17.6","Cell RNA - SK-MEL-30 [nTPM]":"20.4","Cell RNA - SuSa [nTPM]":"15.6","Cell RNA - T-47d [nTPM]":"82.1","Cell RNA - THP-1 [nTPM]":"14.1","Cell RNA - TIME [nTPM]":"25.8","Cell RNA - U-138 MG [nTPM]":"59.3","Cell RNA - U-2 OS [nTPM]":"9.7","Cell RNA - U-2197 [nTPM]":"23.8","Cell RNA - U-251 MG [nTPM]":"15.7","Cell RNA - U-266\/70 [nTPM]":"52.6","Cell RNA - U-266\/84 [nTPM]":"25.8","Cell RNA - U-698 [nTPM]":"17.6","Cell RNA - U-87 MG [nTPM]":"35.9","Cell RNA - U-937 [nTPM]":"14.4","Cell RNA - WM-115 [nTPM]":"43.1","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"12.5","Brain RNA - basal ganglia [nTPM]":"21.6","Brain RNA - cerebellum [nTPM]":"16.6","Brain RNA - cerebral cortex [nTPM]":"16.7","Brain RNA - hippocampal formation [nTPM]":"12.0","Brain RNA - hypothalamus [nTPM]":"15.0","Brain RNA - medulla oblongata [nTPM]":"18.0","Brain RNA - midbrain [nTPM]":"19.2","Brain RNA - pons [nTPM]":"20.1","Brain RNA - spinal cord [nTPM]":"14.2","Brain RNA - thalamus [nTPM]":"19.5","Brain RNA - white matter [nTPM]":"30.0","Single Cell Type RNA - Adipocytes [nTPM]":"14.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"9.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"4.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.8","Single Cell Type RNA - dendritic cells [nTPM]":"11.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"18.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.5","Single Cell Type RNA - Endothelial cells [nTPM]":"12.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"4.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.5","Single Cell Type RNA - Fibroblasts [nTPM]":"26.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"40.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"43.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.6","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"26.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"19.0","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"5.9","Single Cell Type RNA - Muller glia cells [nTPM]":"13.2","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.8","Single Cell Type RNA - Paneth cells [nTPM]":"5.4","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"6.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.5","Single Cell Type RNA - T-cells [nTPM]":"6.0","Single Cell Type RNA - Theca cells [nTPM]":"74.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.0"},{"Gene":"NEU1","Gene synonym":["NEU"],"Ensembl":"ENSG00000204386","Gene description":"Neuraminidase 1","Uniprot":["Q99519"],"Chromosome":"6","Position":"31857659-31862905","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Lipid degradation","Lipid metabolism"],"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"197.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"3.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"3.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"5.4","U-266\/84":"9.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015634","HPA021506"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA015634":"AB_1854386","HPA021506":"AB_1854385"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Tissue RNA - adipose tissue [nTPM]":"23.9","Tissue RNA - adrenal gland [nTPM]":"57.2","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"22.4","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"21.2","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"25.1","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"19.5","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"14.9","Tissue RNA - fallopian tube [nTPM]":"16.8","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"22.5","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"43.7","Tissue RNA - liver [nTPM]":"29.9","Tissue RNA - lung [nTPM]":"28.9","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"20.3","Tissue RNA - pancreas [nTPM]":"35.9","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"33.0","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"26.5","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"38.6","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"21.3","Tissue RNA - skin 1 [nTPM]":"20.1","Tissue RNA - small intestine [nTPM]":"24.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"25.3","Tissue RNA - stomach 1 [nTPM]":"29.8","Tissue RNA - testis [nTPM]":"8.2","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"31.8","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"23.2","Tissue RNA - vagina [nTPM]":"16.2","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"1.4","Cell RNA - ASC diff [nTPM]":"1.8","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"1.5","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"5.4","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"2.5","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"1.8","Cell RNA - HSkMC [nTPM]":"1.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.4","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.9","Cell RNA - K-562 [nTPM]":"1.1","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.9","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"1.0","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"3.7","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"65.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"46.3","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"57.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"34.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"45.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"26.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"87.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"55.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"54.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"62.8","Single Cell Type RNA - dendritic cells [nTPM]":"100.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"83.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"114.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"29.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"53.5","Single Cell Type RNA - Endothelial cells [nTPM]":"42.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"113.5","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"57.8","Single Cell Type RNA - Fibroblasts [nTPM]":"73.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"60.8","Single Cell Type RNA - granulocytes [nTPM]":"67.9","Single Cell Type RNA - Granulosa cells [nTPM]":"17.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.7","Single Cell Type RNA - Hepatocytes [nTPM]":"34.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"170.9","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.9","Single Cell Type RNA - Ionocytes [nTPM]":"79.3","Single Cell Type RNA - Kupffer cells [nTPM]":"63.0","Single Cell Type RNA - Langerhans cells [nTPM]":"65.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"27.7","Single Cell Type RNA - Macrophages [nTPM]":"93.0","Single Cell Type RNA - Melanocytes [nTPM]":"71.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"25.8","Single Cell Type RNA - Muller glia cells [nTPM]":"48.8","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.4","Single Cell Type RNA - Paneth cells [nTPM]":"88.1","Single Cell Type RNA - Peritubular cells [nTPM]":"23.3","Single Cell Type RNA - Plasma cells [nTPM]":"81.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"89.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"115.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"59.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"60.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.7","Single Cell Type RNA - Spermatocytes [nTPM]":"5.4","Single Cell Type RNA - Spermatogonia [nTPM]":"10.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"197.0","Single Cell Type RNA - T-cells [nTPM]":"81.7","Single Cell Type RNA - Theca cells [nTPM]":"40.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.1","Single Cell Type RNA - Urothelial cells [nTPM]":"34.6"},{"Gene":"NPC1","Gene synonym":["SLC65A1"],"Ensembl":"ENSG00000141458","Gene description":"NPC intracellular cholesterol transporter 1","Uniprot":["O15118"],"Chromosome":"18","Position":"23506184-23586506","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cholesterol metabolism","Host-virus interaction","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant","Niemann-Pick disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"110.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"182.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"70.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"273.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026618","CAB070132","HPA077445"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB070132":"AB_10001101","HPA026618":"AB_1854580","HPA077445":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Tissue RNA - adipose tissue [nTPM]":"17.5","Tissue RNA - adrenal gland [nTPM]":"76.7","Tissue RNA - amygdala [nTPM]":"35.1","Tissue RNA - appendix [nTPM]":"16.9","Tissue RNA - basal ganglia [nTPM]":"69.6","Tissue RNA - bone marrow [nTPM]":"42.6","Tissue RNA - breast [nTPM]":"20.0","Tissue RNA - cerebellum [nTPM]":"55.3","Tissue RNA - cerebral cortex [nTPM]":"47.8","Tissue RNA - cervix [nTPM]":"16.7","Tissue RNA - choroid plexus [nTPM]":"28.6","Tissue RNA - colon [nTPM]":"13.7","Tissue RNA - duodenum [nTPM]":"14.5","Tissue RNA - endometrium 1 [nTPM]":"16.7","Tissue RNA - epididymis [nTPM]":"15.0","Tissue RNA - esophagus [nTPM]":"20.5","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"15.3","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"41.1","Tissue RNA - hypothalamus [nTPM]":"44.3","Tissue RNA - kidney [nTPM]":"16.8","Tissue RNA - liver [nTPM]":"15.2","Tissue RNA - lung [nTPM]":"29.0","Tissue RNA - lymph node [nTPM]":"20.4","Tissue RNA - medulla oblongata [nTPM]":"73.3","Tissue RNA - midbrain [nTPM]":"55.8","Tissue RNA - ovary [nTPM]":"16.0","Tissue RNA - pancreas [nTPM]":"11.9","Tissue RNA - parathyroid gland [nTPM]":"72.6","Tissue RNA - pituitary gland [nTPM]":"15.0","Tissue RNA - placenta [nTPM]":"27.8","Tissue RNA - pons [nTPM]":"66.6","Tissue RNA - prostate [nTPM]":"13.1","Tissue RNA - rectum [nTPM]":"12.0","Tissue RNA - retina [nTPM]":"28.0","Tissue RNA - salivary gland [nTPM]":"36.8","Tissue RNA - seminal vesicle [nTPM]":"13.2","Tissue RNA - skeletal muscle [nTPM]":"22.9","Tissue RNA - skin 1 [nTPM]":"24.3","Tissue RNA - small intestine [nTPM]":"17.8","Tissue RNA - smooth muscle [nTPM]":"15.1","Tissue RNA - spinal cord [nTPM]":"49.8","Tissue RNA - spleen [nTPM]":"17.1","Tissue RNA - stomach 1 [nTPM]":"20.4","Tissue RNA - testis [nTPM]":"13.7","Tissue RNA - thalamus [nTPM]":"55.8","Tissue RNA - thymus [nTPM]":"12.2","Tissue RNA - thyroid gland [nTPM]":"11.8","Tissue RNA - tongue [nTPM]":"14.1","Tissue RNA - tonsil [nTPM]":"15.6","Tissue RNA - urinary bladder [nTPM]":"15.8","Tissue RNA - vagina [nTPM]":"18.0","Tissue RNA - white matter [nTPM]":"110.6","Cell RNA - A-431 [nTPM]":"21.5","Cell RNA - A549 [nTPM]":"41.4","Cell RNA - AF22 [nTPM]":"17.8","Cell RNA - AN3-CA [nTPM]":"29.3","Cell RNA - ASC diff [nTPM]":"55.8","Cell RNA - ASC TERT1 [nTPM]":"44.6","Cell RNA - BEWO [nTPM]":"40.7","Cell RNA - BJ [nTPM]":"37.3","Cell RNA - BJ hTERT+ [nTPM]":"81.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"84.3","Cell RNA - CACO-2 [nTPM]":"28.1","Cell RNA - CAPAN-2 [nTPM]":"30.7","Cell RNA - Daudi [nTPM]":"18.4","Cell RNA - EFO-21 [nTPM]":"28.0","Cell RNA - fHDF\/TERT166 [nTPM]":"55.0","Cell RNA - GAMG [nTPM]":"132.8","Cell RNA - HaCaT [nTPM]":"59.3","Cell RNA - HAP1 [nTPM]":"22.6","Cell RNA - HBEC3-KT [nTPM]":"63.2","Cell RNA - HBF TERT88 [nTPM]":"35.2","Cell RNA - HDLM-2 [nTPM]":"15.0","Cell RNA - HEK 293 [nTPM]":"17.9","Cell RNA - HEL [nTPM]":"6.8","Cell RNA - HeLa [nTPM]":"35.7","Cell RNA - Hep G2 [nTPM]":"63.2","Cell RNA - HHSteC [nTPM]":"79.2","Cell RNA - HL-60 [nTPM]":"25.0","Cell RNA - HMC-1 [nTPM]":"28.5","Cell RNA - HSkMC [nTPM]":"42.2","Cell RNA - hTCEpi [nTPM]":"61.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"81.7","Cell RNA - hTERT-HME1 [nTPM]":"273.2","Cell RNA - hTERT-RPE1 [nTPM]":"76.8","Cell RNA - HUVEC TERT2 [nTPM]":"40.3","Cell RNA - JURKAT [nTPM]":"20.7","Cell RNA - K-562 [nTPM]":"20.1","Cell RNA - Karpas-707 [nTPM]":"47.5","Cell RNA - LHCN-M2 [nTPM]":"44.2","Cell RNA - MCF7 [nTPM]":"32.4","Cell RNA - MOLT-4 [nTPM]":"10.6","Cell RNA - NB-4 [nTPM]":"14.9","Cell RNA - NTERA-2 [nTPM]":"12.5","Cell RNA - OE19 [nTPM]":"24.4","Cell RNA - PC-3 [nTPM]":"37.3","Cell RNA - REH [nTPM]":"15.3","Cell RNA - RH-30 [nTPM]":"28.1","Cell RNA - RPMI-8226 [nTPM]":"45.0","Cell RNA - RPTEC TERT1 [nTPM]":"88.8","Cell RNA - RT4 [nTPM]":"51.9","Cell RNA - SCLC-21H [nTPM]":"7.5","Cell RNA - SH-SY5Y [nTPM]":"14.5","Cell RNA - SiHa [nTPM]":"44.6","Cell RNA - SK-BR-3 [nTPM]":"62.0","Cell RNA - SK-MEL-30 [nTPM]":"54.3","Cell RNA - SuSa [nTPM]":"27.7","Cell RNA - T-47d [nTPM]":"15.9","Cell RNA - THP-1 [nTPM]":"19.5","Cell RNA - TIME [nTPM]":"50.0","Cell RNA - U-138 MG [nTPM]":"81.1","Cell RNA - U-2 OS [nTPM]":"15.3","Cell RNA - U-2197 [nTPM]":"32.4","Cell RNA - U-251 MG [nTPM]":"32.3","Cell RNA - U-266\/70 [nTPM]":"29.7","Cell RNA - U-266\/84 [nTPM]":"97.1","Cell RNA - U-698 [nTPM]":"12.2","Cell RNA - U-87 MG [nTPM]":"177.7","Cell RNA - U-937 [nTPM]":"21.8","Cell RNA - WM-115 [nTPM]":"37.1","Blood RNA - basophil [nTPM]":"4.4","Blood RNA - classical monocyte [nTPM]":"9.0","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"29.7","Blood RNA - intermediate monocyte [nTPM]":"8.7","Blood RNA - MAIT T-cell [nTPM]":"20.5","Blood RNA - memory B-cell [nTPM]":"5.0","Blood RNA - memory CD4 T-cell [nTPM]":"12.4","Blood RNA - memory CD8 T-cell [nTPM]":"20.7","Blood RNA - myeloid DC [nTPM]":"4.0","Blood RNA - naive B-cell [nTPM]":"6.7","Blood RNA - naive CD4 T-cell [nTPM]":"5.5","Blood RNA - naive CD8 T-cell [nTPM]":"15.0","Blood RNA - neutrophil [nTPM]":"7.9","Blood RNA - NK-cell [nTPM]":"10.5","Blood RNA - non-classical monocyte [nTPM]":"13.8","Blood RNA - plasmacytoid DC [nTPM]":"70.9","Blood RNA - T-reg [nTPM]":"17.4","Blood RNA - total PBMC [nTPM]":"10.6","Brain RNA - amygdala [nTPM]":"35.1","Brain RNA - basal ganglia [nTPM]":"69.6","Brain RNA - cerebellum [nTPM]":"55.3","Brain RNA - cerebral cortex [nTPM]":"47.8","Brain RNA - hippocampal formation [nTPM]":"41.1","Brain RNA - hypothalamus [nTPM]":"44.3","Brain RNA - medulla oblongata [nTPM]":"73.3","Brain RNA - midbrain [nTPM]":"55.8","Brain RNA - pons [nTPM]":"66.6","Brain RNA - spinal cord [nTPM]":"49.8","Brain RNA - thalamus [nTPM]":"55.8","Brain RNA - white matter [nTPM]":"110.6","Single Cell Type RNA - Adipocytes [nTPM]":"18.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"56.1","Single Cell Type RNA - Astrocytes [nTPM]":"32.7","Single Cell Type RNA - B-cells [nTPM]":"9.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"21.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - dendritic cells [nTPM]":"61.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.2","Single Cell Type RNA - Endothelial cells [nTPM]":"16.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.8","Single Cell Type RNA - Fibroblasts [nTPM]":"13.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"53.9","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"31.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"9.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"11.9","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"21.0","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"59.0","Single Cell Type RNA - monocytes [nTPM]":"7.2","Single Cell Type RNA - Muller glia cells [nTPM]":"15.1","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"182.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.4","Single Cell Type RNA - Paneth cells [nTPM]":"22.6","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"15.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"41.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.4","Single Cell Type RNA - Spermatocytes [nTPM]":"13.9","Single Cell Type RNA - Spermatogonia [nTPM]":"25.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.8","Single Cell Type RNA - T-cells [nTPM]":"19.1","Single Cell Type RNA - Theca cells [nTPM]":"52.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"64.0"},{"Gene":"NPC2","Gene synonym":["EDDM1","HE1","NP-C2"],"Ensembl":"ENSG00000119655","Gene description":"NPC intracellular cholesterol transporter 2","Uniprot":["P61916"],"Chromosome":"14","Position":"74476192-74494177","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Niemann-Pick disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"21","RNA tissue specific nTPM":{"epididymis":"16783.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"2034.2","Hofbauer cells":"2898.5","Kupffer cells":"2035.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"769.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"668.7","classical monocyte":"1300.7","intermediate monocyte":"1772.7","myeloid DC":"587.8","neutrophil":"674.2","non-classical monocyte":"1252.1","plasmacytoid DC":"2113.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"2113.2","granulocytes":"674.2","monocytes":"1772.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1619.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000835","CAB032888"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"53000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB032888":"AB_2157036","HPA000835":"AB_1079499"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.83e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.66e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.55e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Tissue RNA - adipose tissue [nTPM]":"260.1","Tissue RNA - adrenal gland [nTPM]":"297.0","Tissue RNA - amygdala [nTPM]":"127.1","Tissue RNA - appendix [nTPM]":"261.3","Tissue RNA - basal ganglia [nTPM]":"145.4","Tissue RNA - bone marrow [nTPM]":"305.3","Tissue RNA - breast [nTPM]":"221.3","Tissue RNA - cerebellum [nTPM]":"152.2","Tissue RNA - cerebral cortex [nTPM]":"190.6","Tissue RNA - cervix [nTPM]":"284.5","Tissue RNA - choroid plexus [nTPM]":"434.0","Tissue RNA - colon [nTPM]":"259.7","Tissue RNA - duodenum [nTPM]":"201.7","Tissue RNA - endometrium 1 [nTPM]":"196.7","Tissue RNA - epididymis [nTPM]":"16783.1","Tissue RNA - esophagus [nTPM]":"185.0","Tissue RNA - fallopian tube [nTPM]":"170.0","Tissue RNA - gallbladder [nTPM]":"356.0","Tissue RNA - heart muscle [nTPM]":"215.1","Tissue RNA - hippocampal formation [nTPM]":"118.1","Tissue RNA - hypothalamus [nTPM]":"156.9","Tissue RNA - kidney [nTPM]":"322.4","Tissue RNA - liver [nTPM]":"202.4","Tissue RNA - lung [nTPM]":"786.0","Tissue RNA - lymph node [nTPM]":"360.3","Tissue RNA - medulla oblongata [nTPM]":"185.7","Tissue RNA - midbrain [nTPM]":"145.6","Tissue RNA - ovary [nTPM]":"283.1","Tissue RNA - pancreas [nTPM]":"219.9","Tissue RNA - parathyroid gland [nTPM]":"241.3","Tissue RNA - pituitary gland [nTPM]":"197.5","Tissue RNA - placenta [nTPM]":"263.1","Tissue RNA - pons [nTPM]":"179.2","Tissue RNA - prostate [nTPM]":"164.2","Tissue RNA - rectum [nTPM]":"220.8","Tissue RNA - retina [nTPM]":"48.6","Tissue RNA - salivary gland [nTPM]":"221.9","Tissue RNA - seminal vesicle [nTPM]":"261.3","Tissue RNA - skeletal muscle [nTPM]":"58.7","Tissue RNA - skin 1 [nTPM]":"181.6","Tissue RNA - small intestine [nTPM]":"193.3","Tissue RNA - smooth muscle [nTPM]":"180.5","Tissue RNA - spinal cord [nTPM]":"151.1","Tissue RNA - spleen [nTPM]":"305.6","Tissue RNA - stomach 1 [nTPM]":"206.8","Tissue RNA - testis [nTPM]":"156.8","Tissue RNA - thalamus [nTPM]":"172.1","Tissue RNA - thymus [nTPM]":"134.4","Tissue RNA - thyroid gland [nTPM]":"444.7","Tissue RNA - tongue [nTPM]":"114.7","Tissue RNA - tonsil [nTPM]":"241.9","Tissue RNA - urinary bladder [nTPM]":"347.4","Tissue RNA - vagina [nTPM]":"187.9","Tissue RNA - white matter [nTPM]":"195.5","Cell RNA - A-431 [nTPM]":"297.2","Cell RNA - A549 [nTPM]":"199.3","Cell RNA - AF22 [nTPM]":"124.8","Cell RNA - AN3-CA [nTPM]":"179.4","Cell RNA - ASC diff [nTPM]":"1619.3","Cell RNA - ASC TERT1 [nTPM]":"498.6","Cell RNA - BEWO [nTPM]":"404.8","Cell RNA - BJ [nTPM]":"194.1","Cell RNA - BJ hTERT+ [nTPM]":"707.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"200.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"398.9","Cell RNA - CACO-2 [nTPM]":"351.7","Cell RNA - CAPAN-2 [nTPM]":"420.3","Cell RNA - Daudi [nTPM]":"78.6","Cell RNA - EFO-21 [nTPM]":"141.6","Cell RNA - fHDF\/TERT166 [nTPM]":"181.9","Cell RNA - GAMG [nTPM]":"372.6","Cell RNA - HaCaT [nTPM]":"595.9","Cell RNA - HAP1 [nTPM]":"170.0","Cell RNA - HBEC3-KT [nTPM]":"405.5","Cell RNA - HBF TERT88 [nTPM]":"188.6","Cell RNA - HDLM-2 [nTPM]":"120.4","Cell RNA - HEK 293 [nTPM]":"126.3","Cell RNA - HEL [nTPM]":"29.6","Cell RNA - HeLa [nTPM]":"96.7","Cell RNA - Hep G2 [nTPM]":"296.2","Cell RNA - HHSteC [nTPM]":"348.6","Cell RNA - HL-60 [nTPM]":"51.0","Cell RNA - HMC-1 [nTPM]":"548.4","Cell RNA - HSkMC [nTPM]":"467.7","Cell RNA - hTCEpi [nTPM]":"388.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"173.7","Cell RNA - hTERT-HME1 [nTPM]":"336.9","Cell RNA - hTERT-RPE1 [nTPM]":"930.2","Cell RNA - HUVEC TERT2 [nTPM]":"298.1","Cell RNA - JURKAT [nTPM]":"87.0","Cell RNA - K-562 [nTPM]":"32.9","Cell RNA - Karpas-707 [nTPM]":"601.4","Cell RNA - LHCN-M2 [nTPM]":"224.0","Cell RNA - MCF7 [nTPM]":"106.9","Cell RNA - MOLT-4 [nTPM]":"70.1","Cell RNA - NB-4 [nTPM]":"75.9","Cell RNA - NTERA-2 [nTPM]":"52.9","Cell RNA - OE19 [nTPM]":"489.0","Cell RNA - PC-3 [nTPM]":"307.9","Cell RNA - REH [nTPM]":"39.5","Cell RNA - RH-30 [nTPM]":"219.1","Cell RNA - RPMI-8226 [nTPM]":"281.6","Cell RNA - RPTEC TERT1 [nTPM]":"511.1","Cell RNA - RT4 [nTPM]":"735.0","Cell RNA - SCLC-21H [nTPM]":"5.5","Cell RNA - SH-SY5Y [nTPM]":"91.3","Cell RNA - SiHa [nTPM]":"296.3","Cell RNA - SK-BR-3 [nTPM]":"120.3","Cell RNA - SK-MEL-30 [nTPM]":"298.0","Cell RNA - SuSa [nTPM]":"359.6","Cell RNA - T-47d [nTPM]":"205.2","Cell RNA - THP-1 [nTPM]":"225.7","Cell RNA - TIME [nTPM]":"268.9","Cell RNA - U-138 MG [nTPM]":"291.9","Cell RNA - U-2 OS [nTPM]":"342.0","Cell RNA - U-2197 [nTPM]":"396.1","Cell RNA - U-251 MG [nTPM]":"188.2","Cell RNA - U-266\/70 [nTPM]":"253.7","Cell RNA - U-266\/84 [nTPM]":"452.5","Cell RNA - U-698 [nTPM]":"24.2","Cell RNA - U-87 MG [nTPM]":"292.1","Cell RNA - U-937 [nTPM]":"168.4","Cell RNA - WM-115 [nTPM]":"163.4","Blood RNA - basophil [nTPM]":"668.7","Blood RNA - classical monocyte [nTPM]":"1300.7","Blood RNA - eosinophil [nTPM]":"274.1","Blood RNA - gdT-cell [nTPM]":"92.2","Blood RNA - intermediate monocyte [nTPM]":"1772.7","Blood RNA - MAIT T-cell [nTPM]":"87.9","Blood RNA - memory B-cell [nTPM]":"295.2","Blood RNA - memory CD4 T-cell [nTPM]":"126.5","Blood RNA - memory CD8 T-cell [nTPM]":"92.3","Blood RNA - myeloid DC [nTPM]":"587.8","Blood RNA - naive B-cell [nTPM]":"241.8","Blood RNA - naive CD4 T-cell [nTPM]":"120.9","Blood RNA - naive CD8 T-cell [nTPM]":"100.5","Blood RNA - neutrophil [nTPM]":"674.2","Blood RNA - NK-cell [nTPM]":"99.5","Blood RNA - non-classical monocyte [nTPM]":"1252.1","Blood RNA - plasmacytoid DC [nTPM]":"2113.2","Blood RNA - T-reg [nTPM]":"187.8","Blood RNA - total PBMC [nTPM]":"1304.5","Brain RNA - amygdala [nTPM]":"127.1","Brain RNA - basal ganglia [nTPM]":"145.4","Brain RNA - cerebellum [nTPM]":"152.2","Brain RNA - cerebral cortex [nTPM]":"190.6","Brain RNA - hippocampal formation [nTPM]":"118.1","Brain RNA - hypothalamus [nTPM]":"156.9","Brain RNA - medulla oblongata [nTPM]":"185.7","Brain RNA - midbrain [nTPM]":"145.6","Brain RNA - pons [nTPM]":"179.2","Brain RNA - spinal cord [nTPM]":"151.1","Brain RNA - thalamus [nTPM]":"172.1","Brain RNA - white matter [nTPM]":"195.5","Single Cell Type RNA - Adipocytes [nTPM]":"154.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"381.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2034.2","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"160.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"374.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"557.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1074.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"170.2","Single Cell Type RNA - Bipolar cells [nTPM]":"9.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"138.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"220.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"55.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"163.0","Single Cell Type RNA - Club cells [nTPM]":"626.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"331.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"228.3","Single Cell Type RNA - dendritic cells [nTPM]":"664.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"301.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"305.2","Single Cell Type RNA - Ductal cells [nTPM]":"500.4","Single Cell Type RNA - Early spermatids [nTPM]":"90.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"123.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"168.5","Single Cell Type RNA - Endothelial cells [nTPM]":"276.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"119.7","Single Cell Type RNA - Erythroid cells [nTPM]":"65.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"279.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"803.3","Single Cell Type RNA - Fibroblasts [nTPM]":"318.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"61.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"161.0","Single Cell Type RNA - granulocytes [nTPM]":"341.4","Single Cell Type RNA - Granulosa cells [nTPM]":"104.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"447.3","Single Cell Type RNA - Hepatocytes [nTPM]":"195.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2898.5","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"264.8","Single Cell Type RNA - Ionocytes [nTPM]":"832.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2035.4","Single Cell Type RNA - Langerhans cells [nTPM]":"750.9","Single Cell Type RNA - Late spermatids [nTPM]":"69.6","Single Cell Type RNA - Leydig cells [nTPM]":"566.7","Single Cell Type RNA - Macrophages [nTPM]":"1462.6","Single Cell Type RNA - Melanocytes [nTPM]":"602.9","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"790.5","Single Cell Type RNA - Muller glia cells [nTPM]":"167.4","Single Cell Type RNA - NK-cells [nTPM]":"117.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"368.3","Single Cell Type RNA - Paneth cells [nTPM]":"405.1","Single Cell Type RNA - Peritubular cells [nTPM]":"291.9","Single Cell Type RNA - Plasma cells [nTPM]":"287.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"357.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"298.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"969.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"393.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.1","Single Cell Type RNA - Sertoli cells [nTPM]":"131.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"118.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"155.9","Single Cell Type RNA - Spermatocytes [nTPM]":"268.1","Single Cell Type RNA - Spermatogonia [nTPM]":"166.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"182.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"320.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"210.4","Single Cell Type RNA - T-cells [nTPM]":"109.9","Single Cell Type RNA - Theca cells [nTPM]":"330.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"298.5","Single Cell Type RNA - Urothelial cells [nTPM]":"521.6"},{"Gene":"PPT1","Gene synonym":["CLN1","INCL","PPT"],"Ensembl":"ENSG00000131238","Gene description":"Palmitoyl-protein thioesterase 1","Uniprot":["P50897"],"Chromosome":"1","Position":"40072710-40097260","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"251.9","Kupffer cells":"315.8","Langerhans cells":"328.8","Macrophages":"271.3","monocytes":"227.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"1254.3","eosinophil":"624.2","intermediate monocyte":"1006.3","myeloid DC":"1091.1","neutrophil":"683.9","non-classical monocyte":"815.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"1091.1","granulocytes":"683.9","monocytes":"1254.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"1082.7","THP-1":"1449.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021546"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA021546":"AB_1855667"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.98e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"69.8","Tissue RNA - adrenal gland [nTPM]":"59.4","Tissue RNA - amygdala [nTPM]":"92.9","Tissue RNA - appendix [nTPM]":"92.7","Tissue RNA - basal ganglia [nTPM]":"95.6","Tissue RNA - bone marrow [nTPM]":"117.5","Tissue RNA - breast [nTPM]":"95.7","Tissue RNA - cerebellum [nTPM]":"100.4","Tissue RNA - cerebral cortex [nTPM]":"135.9","Tissue RNA - cervix [nTPM]":"70.1","Tissue RNA - choroid plexus [nTPM]":"106.1","Tissue RNA - colon [nTPM]":"50.5","Tissue RNA - duodenum [nTPM]":"32.1","Tissue RNA - endometrium 1 [nTPM]":"72.7","Tissue RNA - epididymis [nTPM]":"60.1","Tissue RNA - esophagus [nTPM]":"45.1","Tissue RNA - fallopian tube [nTPM]":"55.4","Tissue RNA - gallbladder [nTPM]":"57.1","Tissue RNA - heart muscle [nTPM]":"45.3","Tissue RNA - hippocampal formation [nTPM]":"93.6","Tissue RNA - hypothalamus [nTPM]":"101.2","Tissue RNA - kidney [nTPM]":"75.8","Tissue RNA - liver [nTPM]":"54.1","Tissue RNA - lung [nTPM]":"128.5","Tissue RNA - lymph node [nTPM]":"93.9","Tissue RNA - medulla oblongata [nTPM]":"97.0","Tissue RNA - midbrain [nTPM]":"96.7","Tissue RNA - ovary [nTPM]":"68.6","Tissue RNA - pancreas [nTPM]":"42.6","Tissue RNA - parathyroid gland [nTPM]":"79.2","Tissue RNA - pituitary gland [nTPM]":"39.0","Tissue RNA - placenta [nTPM]":"74.8","Tissue RNA - pons [nTPM]":"99.6","Tissue RNA - prostate [nTPM]":"73.4","Tissue RNA - rectum [nTPM]":"58.8","Tissue RNA - retina [nTPM]":"89.4","Tissue RNA - salivary gland [nTPM]":"56.8","Tissue RNA - seminal vesicle [nTPM]":"63.2","Tissue RNA - skeletal muscle [nTPM]":"21.3","Tissue RNA - skin 1 [nTPM]":"40.3","Tissue RNA - small intestine [nTPM]":"39.2","Tissue RNA - smooth muscle [nTPM]":"95.3","Tissue RNA - spinal cord [nTPM]":"101.6","Tissue RNA - spleen [nTPM]":"177.0","Tissue RNA - stomach 1 [nTPM]":"45.1","Tissue RNA - testis [nTPM]":"37.6","Tissue RNA - thalamus [nTPM]":"99.1","Tissue RNA - thymus [nTPM]":"78.0","Tissue RNA - thyroid gland [nTPM]":"60.0","Tissue RNA - tongue [nTPM]":"37.1","Tissue RNA - tonsil [nTPM]":"75.1","Tissue RNA - urinary bladder [nTPM]":"79.1","Tissue RNA - vagina [nTPM]":"34.7","Tissue RNA - white matter [nTPM]":"113.5","Cell RNA - A-431 [nTPM]":"115.6","Cell RNA - A549 [nTPM]":"62.5","Cell RNA - AF22 [nTPM]":"93.7","Cell RNA - AN3-CA [nTPM]":"81.0","Cell RNA - ASC diff [nTPM]":"106.5","Cell RNA - ASC TERT1 [nTPM]":"92.1","Cell RNA - BEWO [nTPM]":"209.8","Cell RNA - BJ [nTPM]":"68.4","Cell RNA - BJ hTERT+ [nTPM]":"127.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"153.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"183.3","Cell RNA - CACO-2 [nTPM]":"350.1","Cell RNA - CAPAN-2 [nTPM]":"270.5","Cell RNA - Daudi [nTPM]":"140.1","Cell RNA - EFO-21 [nTPM]":"118.1","Cell RNA - fHDF\/TERT166 [nTPM]":"65.2","Cell RNA - GAMG [nTPM]":"112.2","Cell RNA - HaCaT [nTPM]":"209.5","Cell RNA - HAP1 [nTPM]":"154.9","Cell RNA - HBEC3-KT [nTPM]":"112.7","Cell RNA - HBF TERT88 [nTPM]":"163.6","Cell RNA - HDLM-2 [nTPM]":"186.4","Cell RNA - HEK 293 [nTPM]":"151.4","Cell RNA - HEL [nTPM]":"100.3","Cell RNA - HeLa [nTPM]":"127.2","Cell RNA - Hep G2 [nTPM]":"155.5","Cell RNA - HHSteC [nTPM]":"137.5","Cell RNA - HL-60 [nTPM]":"233.7","Cell RNA - HMC-1 [nTPM]":"158.9","Cell RNA - HSkMC [nTPM]":"103.1","Cell RNA - hTCEpi [nTPM]":"107.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"108.7","Cell RNA - hTERT-HME1 [nTPM]":"126.4","Cell RNA - hTERT-RPE1 [nTPM]":"79.7","Cell RNA - HUVEC TERT2 [nTPM]":"190.9","Cell RNA - JURKAT [nTPM]":"108.8","Cell RNA - K-562 [nTPM]":"167.7","Cell RNA - Karpas-707 [nTPM]":"247.0","Cell RNA - LHCN-M2 [nTPM]":"80.6","Cell RNA - MCF7 [nTPM]":"168.1","Cell RNA - MOLT-4 [nTPM]":"109.8","Cell RNA - NB-4 [nTPM]":"88.3","Cell RNA - NTERA-2 [nTPM]":"258.3","Cell RNA - OE19 [nTPM]":"163.9","Cell RNA - PC-3 [nTPM]":"93.8","Cell RNA - REH [nTPM]":"116.0","Cell RNA - RH-30 [nTPM]":"263.7","Cell RNA - RPMI-8226 [nTPM]":"226.1","Cell RNA - RPTEC TERT1 [nTPM]":"89.2","Cell RNA - RT4 [nTPM]":"152.0","Cell RNA - SCLC-21H [nTPM]":"114.1","Cell RNA - SH-SY5Y [nTPM]":"96.9","Cell RNA - SiHa [nTPM]":"247.9","Cell RNA - SK-BR-3 [nTPM]":"1082.7","Cell RNA - SK-MEL-30 [nTPM]":"298.6","Cell RNA - SuSa [nTPM]":"111.7","Cell RNA - T-47d [nTPM]":"199.3","Cell RNA - THP-1 [nTPM]":"1449.6","Cell RNA - TIME [nTPM]":"85.2","Cell RNA - U-138 MG [nTPM]":"100.7","Cell RNA - U-2 OS [nTPM]":"147.1","Cell RNA - U-2197 [nTPM]":"70.7","Cell RNA - U-251 MG [nTPM]":"174.9","Cell RNA - U-266\/70 [nTPM]":"161.2","Cell RNA - U-266\/84 [nTPM]":"383.8","Cell RNA - U-698 [nTPM]":"133.9","Cell RNA - U-87 MG [nTPM]":"109.4","Cell RNA - U-937 [nTPM]":"408.7","Cell RNA - WM-115 [nTPM]":"155.5","Blood RNA - basophil [nTPM]":"85.7","Blood RNA - classical monocyte [nTPM]":"1254.3","Blood RNA - eosinophil [nTPM]":"624.2","Blood RNA - gdT-cell [nTPM]":"122.2","Blood RNA - intermediate monocyte [nTPM]":"1006.3","Blood RNA - MAIT T-cell [nTPM]":"137.9","Blood RNA - memory B-cell [nTPM]":"118.8","Blood RNA - memory CD4 T-cell [nTPM]":"171.5","Blood RNA - memory CD8 T-cell [nTPM]":"131.3","Blood RNA - myeloid DC [nTPM]":"1091.1","Blood RNA - naive B-cell [nTPM]":"118.6","Blood RNA - naive CD4 T-cell [nTPM]":"227.0","Blood RNA - naive CD8 T-cell [nTPM]":"168.3","Blood RNA - neutrophil [nTPM]":"683.9","Blood RNA - NK-cell [nTPM]":"100.3","Blood RNA - non-classical monocyte [nTPM]":"815.7","Blood RNA - plasmacytoid DC [nTPM]":"101.8","Blood RNA - T-reg [nTPM]":"204.1","Blood RNA - total PBMC [nTPM]":"1586.9","Brain RNA - amygdala [nTPM]":"92.9","Brain RNA - basal ganglia [nTPM]":"95.6","Brain RNA - cerebellum [nTPM]":"100.4","Brain RNA - cerebral cortex [nTPM]":"135.9","Brain RNA - hippocampal formation [nTPM]":"93.6","Brain RNA - hypothalamus [nTPM]":"101.2","Brain RNA - medulla oblongata [nTPM]":"97.0","Brain RNA - midbrain [nTPM]":"96.7","Brain RNA - pons [nTPM]":"99.6","Brain RNA - spinal cord [nTPM]":"101.6","Brain RNA - thalamus [nTPM]":"99.1","Brain RNA - white matter [nTPM]":"113.5","Single Cell Type RNA - Adipocytes [nTPM]":"45.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.7","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"33.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"77.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Bipolar cells [nTPM]":"46.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"55.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"37.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"40.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"51.7","Single Cell Type RNA - dendritic cells [nTPM]":"28.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"59.0","Single Cell Type RNA - Early spermatids [nTPM]":"64.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.4","Single Cell Type RNA - Endothelial cells [nTPM]":"49.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.9","Single Cell Type RNA - Erythroid cells [nTPM]":"40.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"66.5","Single Cell Type RNA - Fibroblasts [nTPM]":"56.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.2","Single Cell Type RNA - granulocytes [nTPM]":"84.9","Single Cell Type RNA - Granulosa cells [nTPM]":"34.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.5","Single Cell Type RNA - Hepatocytes [nTPM]":"9.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"251.9","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.1","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"315.8","Single Cell Type RNA - Langerhans cells [nTPM]":"328.8","Single Cell Type RNA - Late spermatids [nTPM]":"87.6","Single Cell Type RNA - Leydig cells [nTPM]":"31.4","Single Cell Type RNA - Macrophages [nTPM]":"271.3","Single Cell Type RNA - Melanocytes [nTPM]":"67.6","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"227.2","Single Cell Type RNA - Muller glia cells [nTPM]":"120.3","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.2","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"39.5","Single Cell Type RNA - Plasma cells [nTPM]":"34.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.3","Single Cell Type RNA - Spermatocytes [nTPM]":"17.5","Single Cell Type RNA - Spermatogonia [nTPM]":"33.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"41.2","Single Cell Type RNA - T-cells [nTPM]":"43.5","Single Cell Type RNA - Theca cells [nTPM]":"39.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.4","Single Cell Type RNA - Urothelial cells [nTPM]":"35.6"},{"Gene":"PSAP","Gene synonym":["GLBA","SAP1","SAP2"],"Ensembl":"ENSG00000197746","Gene description":"Prosaposin","Uniprot":["P07602"],"Chromosome":"10","Position":"71816298-71851325","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":null,"Disease involvement":["Disease variant","Gangliosidosis","Gaucher disease","Leukodystrophy","Metachromatic leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"2792.8","Kupffer cells":"2427.0","Macrophages":"1916.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"11615.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"5104.0","hTERT-RPE1":"6978.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004426","CAB004647"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"88000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB004647":"AB_425625","HPA004426":"AB_1079701"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"1068.6","Tissue RNA - adrenal gland [nTPM]":"1192.2","Tissue RNA - amygdala [nTPM]":"831.4","Tissue RNA - appendix [nTPM]":"874.2","Tissue RNA - basal ganglia [nTPM]":"946.7","Tissue RNA - bone marrow [nTPM]":"834.2","Tissue RNA - breast [nTPM]":"683.8","Tissue RNA - cerebellum [nTPM]":"873.7","Tissue RNA - cerebral cortex [nTPM]":"831.7","Tissue RNA - cervix [nTPM]":"1073.9","Tissue RNA - choroid plexus [nTPM]":"1023.0","Tissue RNA - colon [nTPM]":"667.1","Tissue RNA - duodenum [nTPM]":"475.6","Tissue RNA - endometrium 1 [nTPM]":"879.3","Tissue RNA - epididymis [nTPM]":"951.2","Tissue RNA - esophagus [nTPM]":"605.5","Tissue RNA - fallopian tube [nTPM]":"724.7","Tissue RNA - gallbladder [nTPM]":"1115.6","Tissue RNA - heart muscle [nTPM]":"1413.3","Tissue RNA - hippocampal formation [nTPM]":"830.5","Tissue RNA - hypothalamus [nTPM]":"1081.8","Tissue RNA - kidney [nTPM]":"860.4","Tissue RNA - liver [nTPM]":"906.4","Tissue RNA - lung [nTPM]":"1118.6","Tissue RNA - lymph node [nTPM]":"956.1","Tissue RNA - medulla oblongata [nTPM]":"957.6","Tissue RNA - midbrain [nTPM]":"894.0","Tissue RNA - ovary [nTPM]":"1106.9","Tissue RNA - pancreas [nTPM]":"544.7","Tissue RNA - parathyroid gland [nTPM]":"1167.5","Tissue RNA - pituitary gland [nTPM]":"563.5","Tissue RNA - placenta [nTPM]":"869.3","Tissue RNA - pons [nTPM]":"885.3","Tissue RNA - prostate [nTPM]":"773.9","Tissue RNA - rectum [nTPM]":"625.5","Tissue RNA - retina [nTPM]":"665.2","Tissue RNA - salivary gland [nTPM]":"580.9","Tissue RNA - seminal vesicle [nTPM]":"936.8","Tissue RNA - skeletal muscle [nTPM]":"1409.5","Tissue RNA - skin 1 [nTPM]":"544.4","Tissue RNA - small intestine [nTPM]":"487.7","Tissue RNA - smooth muscle [nTPM]":"1138.6","Tissue RNA - spinal cord [nTPM]":"1025.9","Tissue RNA - spleen [nTPM]":"1045.9","Tissue RNA - stomach 1 [nTPM]":"664.0","Tissue RNA - testis [nTPM]":"489.1","Tissue RNA - thalamus [nTPM]":"1048.8","Tissue RNA - thymus [nTPM]":"672.3","Tissue RNA - thyroid gland [nTPM]":"875.9","Tissue RNA - tongue [nTPM]":"987.5","Tissue RNA - tonsil [nTPM]":"560.4","Tissue RNA - urinary bladder [nTPM]":"941.2","Tissue RNA - vagina [nTPM]":"578.3","Tissue RNA - white matter [nTPM]":"1325.1","Cell RNA - A-431 [nTPM]":"455.9","Cell RNA - A549 [nTPM]":"847.4","Cell RNA - AF22 [nTPM]":"540.4","Cell RNA - AN3-CA [nTPM]":"1121.0","Cell RNA - ASC diff [nTPM]":"5104.0","Cell RNA - ASC TERT1 [nTPM]":"2910.1","Cell RNA - BEWO [nTPM]":"1900.2","Cell RNA - BJ [nTPM]":"799.9","Cell RNA - BJ hTERT+ [nTPM]":"2368.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"620.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"735.9","Cell RNA - CACO-2 [nTPM]":"795.4","Cell RNA - CAPAN-2 [nTPM]":"1131.9","Cell RNA - Daudi [nTPM]":"245.6","Cell RNA - EFO-21 [nTPM]":"1608.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1321.6","Cell RNA - GAMG [nTPM]":"1038.9","Cell RNA - HaCaT [nTPM]":"964.1","Cell RNA - HAP1 [nTPM]":"207.5","Cell RNA - HBEC3-KT [nTPM]":"659.1","Cell RNA - HBF TERT88 [nTPM]":"434.8","Cell RNA - HDLM-2 [nTPM]":"481.4","Cell RNA - HEK 293 [nTPM]":"381.8","Cell RNA - HEL [nTPM]":"288.9","Cell RNA - HeLa [nTPM]":"352.3","Cell RNA - Hep G2 [nTPM]":"459.6","Cell RNA - HHSteC [nTPM]":"1970.7","Cell RNA - HL-60 [nTPM]":"188.8","Cell RNA - HMC-1 [nTPM]":"1596.0","Cell RNA - HSkMC [nTPM]":"1871.8","Cell RNA - hTCEpi [nTPM]":"1479.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"625.7","Cell RNA - hTERT-HME1 [nTPM]":"1177.6","Cell RNA - hTERT-RPE1 [nTPM]":"6978.9","Cell RNA - HUVEC TERT2 [nTPM]":"1128.1","Cell RNA - JURKAT [nTPM]":"345.8","Cell RNA - K-562 [nTPM]":"420.5","Cell RNA - Karpas-707 [nTPM]":"1158.1","Cell RNA - LHCN-M2 [nTPM]":"777.0","Cell RNA - MCF7 [nTPM]":"294.9","Cell RNA - MOLT-4 [nTPM]":"843.8","Cell RNA - NB-4 [nTPM]":"290.1","Cell RNA - NTERA-2 [nTPM]":"249.5","Cell RNA - OE19 [nTPM]":"575.4","Cell RNA - PC-3 [nTPM]":"404.0","Cell RNA - REH [nTPM]":"172.9","Cell RNA - RH-30 [nTPM]":"301.3","Cell RNA - RPMI-8226 [nTPM]":"696.7","Cell RNA - RPTEC TERT1 [nTPM]":"730.3","Cell RNA - RT4 [nTPM]":"764.4","Cell RNA - SCLC-21H [nTPM]":"584.4","Cell RNA - SH-SY5Y [nTPM]":"515.8","Cell RNA - SiHa [nTPM]":"751.1","Cell RNA - SK-BR-3 [nTPM]":"2248.3","Cell RNA - SK-MEL-30 [nTPM]":"3122.2","Cell RNA - SuSa [nTPM]":"700.4","Cell RNA - T-47d [nTPM]":"454.4","Cell RNA - THP-1 [nTPM]":"431.1","Cell RNA - TIME [nTPM]":"1467.0","Cell RNA - U-138 MG [nTPM]":"861.8","Cell RNA - U-2 OS [nTPM]":"610.0","Cell RNA - U-2197 [nTPM]":"587.1","Cell RNA - U-251 MG [nTPM]":"670.5","Cell RNA - U-266\/70 [nTPM]":"1289.0","Cell RNA - U-266\/84 [nTPM]":"1038.7","Cell RNA - U-698 [nTPM]":"435.4","Cell RNA - U-87 MG [nTPM]":"1375.5","Cell RNA - U-937 [nTPM]":"374.4","Cell RNA - WM-115 [nTPM]":"650.0","Blood RNA - basophil [nTPM]":"863.2","Blood RNA - classical monocyte [nTPM]":"10095.9","Blood RNA - eosinophil [nTPM]":"1127.5","Blood RNA - gdT-cell [nTPM]":"424.2","Blood RNA - intermediate monocyte [nTPM]":"11615.6","Blood RNA - MAIT T-cell [nTPM]":"349.8","Blood RNA - memory B-cell [nTPM]":"466.7","Blood RNA - memory CD4 T-cell [nTPM]":"342.9","Blood RNA - memory CD8 T-cell [nTPM]":"368.8","Blood RNA - myeloid DC [nTPM]":"3481.1","Blood RNA - naive B-cell [nTPM]":"425.5","Blood RNA - naive CD4 T-cell [nTPM]":"370.1","Blood RNA - naive CD8 T-cell [nTPM]":"350.6","Blood RNA - neutrophil [nTPM]":"2890.4","Blood RNA - NK-cell [nTPM]":"365.8","Blood RNA - non-classical monocyte [nTPM]":"10148.2","Blood RNA - plasmacytoid DC [nTPM]":"1758.2","Blood RNA - T-reg [nTPM]":"422.8","Blood RNA - total PBMC [nTPM]":"15009.0","Brain RNA - amygdala [nTPM]":"831.4","Brain RNA - basal ganglia [nTPM]":"946.7","Brain RNA - cerebellum [nTPM]":"873.7","Brain RNA - cerebral cortex [nTPM]":"831.7","Brain RNA - hippocampal formation [nTPM]":"830.5","Brain RNA - hypothalamus [nTPM]":"1081.8","Brain RNA - medulla oblongata [nTPM]":"957.6","Brain RNA - midbrain [nTPM]":"894.0","Brain RNA - pons [nTPM]":"885.3","Brain RNA - spinal cord [nTPM]":"1025.9","Brain RNA - thalamus [nTPM]":"1048.8","Brain RNA - white matter [nTPM]":"1325.1","Single Cell Type RNA - Adipocytes [nTPM]":"263.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"253.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"339.0","Single Cell Type RNA - Astrocytes [nTPM]":"136.8","Single Cell Type RNA - B-cells [nTPM]":"173.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"228.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"253.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"487.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"108.1","Single Cell Type RNA - Bipolar cells [nTPM]":"193.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"254.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"158.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"664.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"253.1","Single Cell Type RNA - Club cells [nTPM]":"318.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"476.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"127.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"891.6","Single Cell Type RNA - dendritic cells [nTPM]":"260.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"434.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"70.5","Single Cell Type RNA - Ductal cells [nTPM]":"1043.6","Single Cell Type RNA - Early spermatids [nTPM]":"19.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"147.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"246.6","Single Cell Type RNA - Endothelial cells [nTPM]":"311.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"261.9","Single Cell Type RNA - Erythroid cells [nTPM]":"160.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"86.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"456.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"872.6","Single Cell Type RNA - Fibroblasts [nTPM]":"623.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"187.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"195.2","Single Cell Type RNA - granulocytes [nTPM]":"398.1","Single Cell Type RNA - Granulosa cells [nTPM]":"210.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"426.9","Single Cell Type RNA - Hepatocytes [nTPM]":"509.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"2792.8","Single Cell Type RNA - Horizontal cells [nTPM]":"333.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"93.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"242.2","Single Cell Type RNA - Ionocytes [nTPM]":"343.8","Single Cell Type RNA - Kupffer cells [nTPM]":"2427.0","Single Cell Type RNA - Langerhans cells [nTPM]":"779.7","Single Cell Type RNA - Late spermatids [nTPM]":"54.1","Single Cell Type RNA - Leydig cells [nTPM]":"458.6","Single Cell Type RNA - Macrophages [nTPM]":"1916.9","Single Cell Type RNA - Melanocytes [nTPM]":"663.5","Single Cell Type RNA - Microglial cells [nTPM]":"105.9","Single Cell Type RNA - monocytes [nTPM]":"1528.9","Single Cell Type RNA - Muller glia cells [nTPM]":"495.6","Single Cell Type RNA - NK-cells [nTPM]":"182.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"92.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"117.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"357.7","Single Cell Type RNA - Paneth cells [nTPM]":"298.3","Single Cell Type RNA - Peritubular cells [nTPM]":"551.8","Single Cell Type RNA - Plasma cells [nTPM]":"503.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"244.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"370.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"311.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"297.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"164.3","Single Cell Type RNA - Sertoli cells [nTPM]":"276.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"273.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"263.8","Single Cell Type RNA - Spermatocytes [nTPM]":"55.2","Single Cell Type RNA - Spermatogonia [nTPM]":"126.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"137.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"198.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1073.2","Single Cell Type RNA - T-cells [nTPM]":"138.9","Single Cell Type RNA - Theca cells [nTPM]":"624.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"228.3","Single Cell Type RNA - Urothelial cells [nTPM]":"223.9"},{"Gene":"SGSH","Gene synonym":["HSS","MPS3A","SFMD"],"Ensembl":"ENSG00000181523","Gene description":"N-sulfoglucosamine sulfohydrolase","Uniprot":["P51688"],"Chromosome":"17","Position":"80206716-80220923","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Theca cells":"32.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"62.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023436","HPA023451"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023436":"AB_1856806","HPA023451":"AB_1856807"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.71e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.72e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.10e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.37e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.6","Tissue RNA - adrenal gland [nTPM]":"45.9","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"12.2","Tissue RNA - basal ganglia [nTPM]":"2.3","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"17.2","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"13.5","Tissue RNA - choroid plexus [nTPM]":"8.8","Tissue RNA - colon [nTPM]":"14.8","Tissue RNA - duodenum [nTPM]":"12.7","Tissue RNA - endometrium 1 [nTPM]":"17.2","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"5.4","Tissue RNA - kidney [nTPM]":"15.7","Tissue RNA - liver [nTPM]":"9.5","Tissue RNA - lung [nTPM]":"18.1","Tissue RNA - lymph node [nTPM]":"13.4","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"12.3","Tissue RNA - pancreas [nTPM]":"20.4","Tissue RNA - parathyroid gland [nTPM]":"16.0","Tissue RNA - pituitary gland [nTPM]":"17.0","Tissue RNA - placenta [nTPM]":"12.4","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"19.7","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"21.8","Tissue RNA - seminal vesicle [nTPM]":"11.1","Tissue RNA - skeletal muscle [nTPM]":"7.0","Tissue RNA - skin 1 [nTPM]":"18.9","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"10.6","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"28.4","Tissue RNA - stomach 1 [nTPM]":"17.8","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"21.2","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"6.9","Tissue RNA - urinary bladder [nTPM]":"15.5","Tissue RNA - vagina [nTPM]":"11.5","Tissue RNA - white matter [nTPM]":"1.8","Cell RNA - A-431 [nTPM]":"2.6","Cell RNA - A549 [nTPM]":"7.9","Cell RNA - AF22 [nTPM]":"9.8","Cell RNA - AN3-CA [nTPM]":"15.6","Cell RNA - ASC diff [nTPM]":"22.5","Cell RNA - ASC TERT1 [nTPM]":"20.2","Cell RNA - BEWO [nTPM]":"10.4","Cell RNA - BJ [nTPM]":"16.0","Cell RNA - BJ hTERT+ [nTPM]":"40.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.2","Cell RNA - CACO-2 [nTPM]":"9.0","Cell RNA - CAPAN-2 [nTPM]":"9.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"25.7","Cell RNA - fHDF\/TERT166 [nTPM]":"24.9","Cell RNA - GAMG [nTPM]":"13.2","Cell RNA - HaCaT [nTPM]":"9.9","Cell RNA - HAP1 [nTPM]":"6.2","Cell RNA - HBEC3-KT [nTPM]":"11.7","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"5.3","Cell RNA - HEK 293 [nTPM]":"9.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"22.3","Cell RNA - Hep G2 [nTPM]":"25.0","Cell RNA - HHSteC [nTPM]":"62.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"5.9","Cell RNA - HSkMC [nTPM]":"33.9","Cell RNA - hTCEpi [nTPM]":"12.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.9","Cell RNA - hTERT-HME1 [nTPM]":"10.5","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"50.7","Cell RNA - JURKAT [nTPM]":"4.7","Cell RNA - K-562 [nTPM]":"7.1","Cell RNA - Karpas-707 [nTPM]":"26.2","Cell RNA - LHCN-M2 [nTPM]":"17.9","Cell RNA - MCF7 [nTPM]":"16.2","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"10.0","Cell RNA - PC-3 [nTPM]":"13.2","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"21.1","Cell RNA - RPTEC TERT1 [nTPM]":"20.2","Cell RNA - RT4 [nTPM]":"18.5","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"11.7","Cell RNA - SiHa [nTPM]":"18.4","Cell RNA - SK-BR-3 [nTPM]":"44.1","Cell RNA - SK-MEL-30 [nTPM]":"10.6","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"32.8","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"32.5","Cell RNA - U-138 MG [nTPM]":"31.9","Cell RNA - U-2 OS [nTPM]":"7.0","Cell RNA - U-2197 [nTPM]":"11.4","Cell RNA - U-251 MG [nTPM]":"7.4","Cell RNA - U-266\/70 [nTPM]":"26.1","Cell RNA - U-266\/84 [nTPM]":"3.6","Cell RNA - U-698 [nTPM]":"3.9","Cell RNA - U-87 MG [nTPM]":"13.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"16.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"20.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"12.1","Blood RNA - intermediate monocyte [nTPM]":"8.0","Blood RNA - MAIT T-cell [nTPM]":"16.0","Blood RNA - memory B-cell [nTPM]":"3.5","Blood RNA - memory CD4 T-cell [nTPM]":"10.5","Blood RNA - memory CD8 T-cell [nTPM]":"11.3","Blood RNA - myeloid DC [nTPM]":"20.4","Blood RNA - naive B-cell [nTPM]":"3.8","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"9.3","Blood RNA - non-classical monocyte [nTPM]":"8.0","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"13.5","Blood RNA - total PBMC [nTPM]":"12.7","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"2.3","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"5.4","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"1.8","Single Cell Type RNA - Adipocytes [nTPM]":"7.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.8","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"5.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.2","Single Cell Type RNA - dendritic cells [nTPM]":"5.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.2","Single Cell Type RNA - Endothelial cells [nTPM]":"10.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.7","Single Cell Type RNA - Fibroblasts [nTPM]":"10.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"4.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"13.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"8.4","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.8","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"5.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.0","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"32.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.9"},{"Gene":"SLC17A5","Gene synonym":["AST","ISSD","NSD","SD","SIALIN","SIASD","SLD"],"Ensembl":"ENSG00000119899","Gene description":"Solute carrier family 17 member 5","Uniprot":["Q9NRA2"],"Chromosome":"6","Position":"73593379-73653992","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"parathyroid gland":"310.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"47.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"99.9","ASC TERT1":"74.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044479"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA044479":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.52e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.4","Tissue RNA - adrenal gland [nTPM]":"10.5","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"6.4","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"6.8","Tissue RNA - breast [nTPM]":"13.8","Tissue RNA - cerebellum [nTPM]":"6.2","Tissue RNA - cerebral cortex [nTPM]":"7.0","Tissue RNA - cervix [nTPM]":"10.7","Tissue RNA - choroid plexus [nTPM]":"5.9","Tissue RNA - colon [nTPM]":"20.4","Tissue RNA - duodenum [nTPM]":"16.4","Tissue RNA - endometrium 1 [nTPM]":"9.4","Tissue RNA - epididymis [nTPM]":"44.6","Tissue RNA - esophagus [nTPM]":"8.4","Tissue RNA - fallopian tube [nTPM]":"5.3","Tissue RNA - gallbladder [nTPM]":"10.4","Tissue RNA - heart muscle [nTPM]":"8.5","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"8.5","Tissue RNA - kidney [nTPM]":"31.9","Tissue RNA - liver [nTPM]":"17.6","Tissue RNA - lung [nTPM]":"13.2","Tissue RNA - lymph node [nTPM]":"5.3","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"7.0","Tissue RNA - ovary [nTPM]":"4.0","Tissue RNA - pancreas [nTPM]":"11.6","Tissue RNA - parathyroid gland [nTPM]":"310.5","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"21.7","Tissue RNA - pons [nTPM]":"7.8","Tissue RNA - prostate [nTPM]":"16.8","Tissue RNA - rectum [nTPM]":"22.1","Tissue RNA - retina [nTPM]":"18.3","Tissue RNA - salivary gland [nTPM]":"30.3","Tissue RNA - seminal vesicle [nTPM]":"14.7","Tissue RNA - skeletal muscle [nTPM]":"5.4","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"21.1","Tissue RNA - smooth muscle [nTPM]":"10.6","Tissue RNA - spinal cord [nTPM]":"5.7","Tissue RNA - spleen [nTPM]":"7.0","Tissue RNA - stomach 1 [nTPM]":"14.4","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"4.5","Tissue RNA - thyroid gland [nTPM]":"43.5","Tissue RNA - tongue [nTPM]":"6.2","Tissue RNA - tonsil [nTPM]":"5.6","Tissue RNA - urinary bladder [nTPM]":"12.6","Tissue RNA - vagina [nTPM]":"6.3","Tissue RNA - white matter [nTPM]":"7.6","Cell RNA - A-431 [nTPM]":"7.4","Cell RNA - A549 [nTPM]":"9.9","Cell RNA - AF22 [nTPM]":"9.7","Cell RNA - AN3-CA [nTPM]":"15.6","Cell RNA - ASC diff [nTPM]":"99.9","Cell RNA - ASC TERT1 [nTPM]":"74.2","Cell RNA - BEWO [nTPM]":"12.8","Cell RNA - BJ [nTPM]":"23.8","Cell RNA - BJ hTERT+ [nTPM]":"59.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.0","Cell RNA - CACO-2 [nTPM]":"6.6","Cell RNA - CAPAN-2 [nTPM]":"17.6","Cell RNA - Daudi [nTPM]":"6.8","Cell RNA - EFO-21 [nTPM]":"11.2","Cell RNA - fHDF\/TERT166 [nTPM]":"32.9","Cell RNA - GAMG [nTPM]":"14.8","Cell RNA - HaCaT [nTPM]":"12.6","Cell RNA - HAP1 [nTPM]":"13.7","Cell RNA - HBEC3-KT [nTPM]":"5.9","Cell RNA - HBF TERT88 [nTPM]":"11.2","Cell RNA - HDLM-2 [nTPM]":"4.8","Cell RNA - HEK 293 [nTPM]":"15.5","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"5.1","Cell RNA - Hep G2 [nTPM]":"15.4","Cell RNA - HHSteC [nTPM]":"19.4","Cell RNA - HL-60 [nTPM]":"5.6","Cell RNA - HMC-1 [nTPM]":"10.8","Cell RNA - HSkMC [nTPM]":"34.2","Cell RNA - hTCEpi [nTPM]":"8.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.2","Cell RNA - hTERT-HME1 [nTPM]":"9.7","Cell RNA - hTERT-RPE1 [nTPM]":"26.4","Cell RNA - HUVEC TERT2 [nTPM]":"16.2","Cell RNA - JURKAT [nTPM]":"9.0","Cell RNA - K-562 [nTPM]":"7.1","Cell RNA - Karpas-707 [nTPM]":"7.2","Cell RNA - LHCN-M2 [nTPM]":"22.3","Cell RNA - MCF7 [nTPM]":"4.9","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"3.3","Cell RNA - NTERA-2 [nTPM]":"7.1","Cell RNA - OE19 [nTPM]":"30.9","Cell RNA - PC-3 [nTPM]":"5.7","Cell RNA - REH [nTPM]":"5.0","Cell RNA - RH-30 [nTPM]":"12.1","Cell RNA - RPMI-8226 [nTPM]":"28.5","Cell RNA - RPTEC TERT1 [nTPM]":"16.0","Cell RNA - RT4 [nTPM]":"20.2","Cell RNA - SCLC-21H [nTPM]":"3.8","Cell RNA - SH-SY5Y [nTPM]":"6.7","Cell RNA - SiHa [nTPM]":"4.8","Cell RNA - SK-BR-3 [nTPM]":"14.0","Cell RNA - SK-MEL-30 [nTPM]":"14.4","Cell RNA - SuSa [nTPM]":"14.0","Cell RNA - T-47d [nTPM]":"6.3","Cell RNA - THP-1 [nTPM]":"34.1","Cell RNA - TIME [nTPM]":"23.5","Cell RNA - U-138 MG [nTPM]":"3.0","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"12.1","Cell RNA - U-251 MG [nTPM]":"5.7","Cell RNA - U-266\/70 [nTPM]":"20.4","Cell RNA - U-266\/84 [nTPM]":"30.6","Cell RNA - U-698 [nTPM]":"1.9","Cell RNA - U-87 MG [nTPM]":"10.5","Cell RNA - U-937 [nTPM]":"11.6","Cell RNA - WM-115 [nTPM]":"9.0","Blood RNA - basophil [nTPM]":"13.3","Blood RNA - classical monocyte [nTPM]":"7.9","Blood RNA - eosinophil [nTPM]":"3.3","Blood RNA - gdT-cell [nTPM]":"6.0","Blood RNA - intermediate monocyte [nTPM]":"7.4","Blood RNA - MAIT T-cell [nTPM]":"5.8","Blood RNA - memory B-cell [nTPM]":"3.9","Blood RNA - memory CD4 T-cell [nTPM]":"6.6","Blood RNA - memory CD8 T-cell [nTPM]":"5.8","Blood RNA - myeloid DC [nTPM]":"7.6","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"5.4","Blood RNA - naive CD8 T-cell [nTPM]":"6.0","Blood RNA - neutrophil [nTPM]":"5.7","Blood RNA - NK-cell [nTPM]":"8.9","Blood RNA - non-classical monocyte [nTPM]":"4.8","Blood RNA - plasmacytoid DC [nTPM]":"5.5","Blood RNA - T-reg [nTPM]":"6.6","Blood RNA - total PBMC [nTPM]":"4.9","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"6.2","Brain RNA - cerebral cortex [nTPM]":"7.0","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"8.5","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"7.0","Brain RNA - pons [nTPM]":"7.8","Brain RNA - spinal cord [nTPM]":"5.7","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"7.6","Single Cell Type RNA - Adipocytes [nTPM]":"8.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.7","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"8.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"17.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"46.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.2","Single Cell Type RNA - Early spermatids [nTPM]":"36.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"13.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"47.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.5","Single Cell Type RNA - Fibroblasts [nTPM]":"25.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.6","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"3.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.9","Single Cell Type RNA - Hepatocytes [nTPM]":"32.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"64.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"47.7","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"24.8","Single Cell Type RNA - Langerhans cells [nTPM]":"22.7","Single Cell Type RNA - Late spermatids [nTPM]":"48.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"25.4","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"11.2","Single Cell Type RNA - Muller glia cells [nTPM]":"8.3","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.2","Single Cell Type RNA - Paneth cells [nTPM]":"17.5","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"20.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.1","Single Cell Type RNA - Spermatocytes [nTPM]":"8.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.8","Single Cell Type RNA - T-cells [nTPM]":"11.0","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.2","Single Cell Type RNA - Urothelial cells [nTPM]":"30.7"},{"Gene":"SMPD1","Gene synonym":["ASM"],"Ensembl":"ENSG00000166311","Gene description":"Sphingomyelin phosphodiesterase 1","Uniprot":["P17405"],"Chromosome":"11","Position":"6390440-6394998","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Neurodegeneration","Niemann-Pick disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"131.3","Late spermatids":"200.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"139.1","fHDF\/TERT166":"144.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.72e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.47e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.57e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.8","Tissue RNA - adrenal gland [nTPM]":"36.5","Tissue RNA - amygdala [nTPM]":"38.8","Tissue RNA - appendix [nTPM]":"13.9","Tissue RNA - basal ganglia [nTPM]":"44.7","Tissue RNA - bone marrow [nTPM]":"7.3","Tissue RNA - breast [nTPM]":"20.1","Tissue RNA - cerebellum [nTPM]":"45.1","Tissue RNA - cerebral cortex [nTPM]":"43.0","Tissue RNA - cervix [nTPM]":"21.2","Tissue RNA - choroid plexus [nTPM]":"33.9","Tissue RNA - colon [nTPM]":"25.3","Tissue RNA - duodenum [nTPM]":"16.8","Tissue RNA - endometrium 1 [nTPM]":"20.9","Tissue RNA - epididymis [nTPM]":"14.4","Tissue RNA - esophagus [nTPM]":"20.6","Tissue RNA - fallopian tube [nTPM]":"14.6","Tissue RNA - gallbladder [nTPM]":"21.5","Tissue RNA - heart muscle [nTPM]":"55.8","Tissue RNA - hippocampal formation [nTPM]":"39.1","Tissue RNA - hypothalamus [nTPM]":"43.0","Tissue RNA - kidney [nTPM]":"73.7","Tissue RNA - liver [nTPM]":"95.3","Tissue RNA - lung [nTPM]":"31.3","Tissue RNA - lymph node [nTPM]":"14.6","Tissue RNA - medulla oblongata [nTPM]":"42.7","Tissue RNA - midbrain [nTPM]":"42.6","Tissue RNA - ovary [nTPM]":"17.9","Tissue RNA - pancreas [nTPM]":"32.8","Tissue RNA - parathyroid gland [nTPM]":"34.2","Tissue RNA - pituitary gland [nTPM]":"41.9","Tissue RNA - placenta [nTPM]":"21.6","Tissue RNA - pons [nTPM]":"43.3","Tissue RNA - prostate [nTPM]":"29.4","Tissue RNA - rectum [nTPM]":"14.9","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"29.0","Tissue RNA - seminal vesicle [nTPM]":"20.0","Tissue RNA - skeletal muscle [nTPM]":"37.9","Tissue RNA - skin 1 [nTPM]":"37.9","Tissue RNA - small intestine [nTPM]":"23.8","Tissue RNA - smooth muscle [nTPM]":"17.6","Tissue RNA - spinal cord [nTPM]":"40.9","Tissue RNA - spleen [nTPM]":"21.1","Tissue RNA - stomach 1 [nTPM]":"25.4","Tissue RNA - testis [nTPM]":"14.0","Tissue RNA - thalamus [nTPM]":"47.5","Tissue RNA - thymus [nTPM]":"17.8","Tissue RNA - thyroid gland [nTPM]":"34.0","Tissue RNA - tongue [nTPM]":"29.4","Tissue RNA - tonsil [nTPM]":"11.0","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"21.0","Tissue RNA - white matter [nTPM]":"46.8","Cell RNA - A-431 [nTPM]":"16.4","Cell RNA - A549 [nTPM]":"13.1","Cell RNA - AF22 [nTPM]":"10.1","Cell RNA - AN3-CA [nTPM]":"26.5","Cell RNA - ASC diff [nTPM]":"139.1","Cell RNA - ASC TERT1 [nTPM]":"72.2","Cell RNA - BEWO [nTPM]":"17.1","Cell RNA - BJ [nTPM]":"60.4","Cell RNA - BJ hTERT+ [nTPM]":"95.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.0","Cell RNA - CACO-2 [nTPM]":"22.0","Cell RNA - CAPAN-2 [nTPM]":"11.9","Cell RNA - Daudi [nTPM]":"4.7","Cell RNA - EFO-21 [nTPM]":"27.4","Cell RNA - fHDF\/TERT166 [nTPM]":"144.0","Cell RNA - GAMG [nTPM]":"59.3","Cell RNA - HaCaT [nTPM]":"7.4","Cell RNA - HAP1 [nTPM]":"8.4","Cell RNA - HBEC3-KT [nTPM]":"12.7","Cell RNA - HBF TERT88 [nTPM]":"13.0","Cell RNA - HDLM-2 [nTPM]":"21.0","Cell RNA - HEK 293 [nTPM]":"9.6","Cell RNA - HEL [nTPM]":"5.1","Cell RNA - HeLa [nTPM]":"19.5","Cell RNA - Hep G2 [nTPM]":"6.0","Cell RNA - HHSteC [nTPM]":"62.3","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"37.4","Cell RNA - HSkMC [nTPM]":"96.0","Cell RNA - hTCEpi [nTPM]":"23.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.9","Cell RNA - hTERT-HME1 [nTPM]":"17.7","Cell RNA - hTERT-RPE1 [nTPM]":"100.9","Cell RNA - HUVEC TERT2 [nTPM]":"61.6","Cell RNA - JURKAT [nTPM]":"1.7","Cell RNA - K-562 [nTPM]":"9.1","Cell RNA - Karpas-707 [nTPM]":"30.5","Cell RNA - LHCN-M2 [nTPM]":"58.9","Cell RNA - MCF7 [nTPM]":"17.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"6.5","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"23.2","Cell RNA - PC-3 [nTPM]":"22.3","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"5.5","Cell RNA - RPMI-8226 [nTPM]":"7.0","Cell RNA - RPTEC TERT1 [nTPM]":"23.9","Cell RNA - RT4 [nTPM]":"6.2","Cell RNA - SCLC-21H [nTPM]":"17.0","Cell RNA - SH-SY5Y [nTPM]":"9.7","Cell RNA - SiHa [nTPM]":"27.6","Cell RNA - SK-BR-3 [nTPM]":"19.5","Cell RNA - SK-MEL-30 [nTPM]":"38.5","Cell RNA - SuSa [nTPM]":"12.9","Cell RNA - T-47d [nTPM]":"7.3","Cell RNA - THP-1 [nTPM]":"7.0","Cell RNA - TIME [nTPM]":"53.9","Cell RNA - U-138 MG [nTPM]":"103.0","Cell RNA - U-2 OS [nTPM]":"10.9","Cell RNA - U-2197 [nTPM]":"59.1","Cell RNA - U-251 MG [nTPM]":"15.4","Cell RNA - U-266\/70 [nTPM]":"37.6","Cell RNA - U-266\/84 [nTPM]":"44.0","Cell RNA - U-698 [nTPM]":"3.5","Cell RNA - U-87 MG [nTPM]":"93.7","Cell RNA - U-937 [nTPM]":"10.8","Cell RNA - WM-115 [nTPM]":"47.1","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"6.4","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"5.0","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"10.0","Blood RNA - naive CD8 T-cell [nTPM]":"10.1","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"6.6","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"4.7","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"38.8","Brain RNA - basal ganglia [nTPM]":"44.7","Brain RNA - cerebellum [nTPM]":"45.1","Brain RNA - cerebral cortex [nTPM]":"43.0","Brain RNA - hippocampal formation [nTPM]":"39.1","Brain RNA - hypothalamus [nTPM]":"43.0","Brain RNA - medulla oblongata [nTPM]":"42.7","Brain RNA - midbrain [nTPM]":"42.6","Brain RNA - pons [nTPM]":"43.3","Brain RNA - spinal cord [nTPM]":"40.9","Brain RNA - thalamus [nTPM]":"47.5","Brain RNA - white matter [nTPM]":"46.8","Single Cell Type RNA - Adipocytes [nTPM]":"14.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.4","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"12.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"12.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"12.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.8","Single Cell Type RNA - dendritic cells [nTPM]":"11.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"131.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"53.4","Single Cell Type RNA - Early spermatids [nTPM]":"50.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.0","Single Cell Type RNA - Endothelial cells [nTPM]":"18.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.4","Single Cell Type RNA - Fibroblasts [nTPM]":"31.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.0","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"9.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"88.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.1","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.3","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"15.5","Single Cell Type RNA - Langerhans cells [nTPM]":"6.2","Single Cell Type RNA - Late spermatids [nTPM]":"200.7","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"15.8","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"7.8","Single Cell Type RNA - Muller glia cells [nTPM]":"16.4","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.7","Single Cell Type RNA - Paneth cells [nTPM]":"83.1","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"23.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"75.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.3","Single Cell Type RNA - T-cells [nTPM]":"23.3","Single Cell Type RNA - Theca cells [nTPM]":"10.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.0","Single Cell Type RNA - Urothelial cells [nTPM]":"15.4"},{"Gene":"SUMF1","Gene synonym":["FGE","UNQ3037"],"Ensembl":"ENSG00000144455","Gene description":"Sulfatase modifying factor 1","Uniprot":["Q8NBK3"],"Chromosome":"3","Position":"3700814-4467273","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Ichthyosis","Leukodystrophy","Metachromatic leukodystrophy","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"85.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"116.4","hTERT-RPE1":"117.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038025"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2800000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038025":"AB_10675624"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.79e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.7","Tissue RNA - adrenal gland [nTPM]":"19.5","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"13.1","Tissue RNA - basal ganglia [nTPM]":"12.0","Tissue RNA - bone marrow [nTPM]":"10.2","Tissue RNA - breast [nTPM]":"29.2","Tissue RNA - cerebellum [nTPM]":"10.9","Tissue RNA - cerebral cortex [nTPM]":"12.2","Tissue RNA - cervix [nTPM]":"21.3","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"23.9","Tissue RNA - duodenum [nTPM]":"13.3","Tissue RNA - endometrium 1 [nTPM]":"15.8","Tissue RNA - epididymis [nTPM]":"26.8","Tissue RNA - esophagus [nTPM]":"28.7","Tissue RNA - fallopian tube [nTPM]":"25.6","Tissue RNA - gallbladder [nTPM]":"19.7","Tissue RNA - heart muscle [nTPM]":"12.5","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"39.3","Tissue RNA - liver [nTPM]":"27.4","Tissue RNA - lung [nTPM]":"23.0","Tissue RNA - lymph node [nTPM]":"12.6","Tissue RNA - medulla oblongata [nTPM]":"12.2","Tissue RNA - midbrain [nTPM]":"11.7","Tissue RNA - ovary [nTPM]":"17.4","Tissue RNA - pancreas [nTPM]":"18.9","Tissue RNA - parathyroid gland [nTPM]":"46.8","Tissue RNA - pituitary gland [nTPM]":"14.5","Tissue RNA - placenta [nTPM]":"18.8","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"22.1","Tissue RNA - rectum [nTPM]":"29.6","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"22.8","Tissue RNA - seminal vesicle [nTPM]":"17.7","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"20.3","Tissue RNA - small intestine [nTPM]":"14.1","Tissue RNA - smooth muscle [nTPM]":"20.5","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"16.8","Tissue RNA - stomach 1 [nTPM]":"23.8","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"13.1","Tissue RNA - thymus [nTPM]":"10.6","Tissue RNA - thyroid gland [nTPM]":"28.4","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"13.4","Tissue RNA - urinary bladder [nTPM]":"20.0","Tissue RNA - vagina [nTPM]":"18.5","Tissue RNA - white matter [nTPM]":"13.1","Cell RNA - A-431 [nTPM]":"25.0","Cell RNA - A549 [nTPM]":"20.6","Cell RNA - AF22 [nTPM]":"11.4","Cell RNA - AN3-CA [nTPM]":"6.3","Cell RNA - ASC diff [nTPM]":"116.4","Cell RNA - ASC TERT1 [nTPM]":"61.3","Cell RNA - BEWO [nTPM]":"21.9","Cell RNA - BJ [nTPM]":"34.4","Cell RNA - BJ hTERT+ [nTPM]":"53.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.2","Cell RNA - CACO-2 [nTPM]":"9.6","Cell RNA - CAPAN-2 [nTPM]":"78.9","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"20.3","Cell RNA - fHDF\/TERT166 [nTPM]":"63.0","Cell RNA - GAMG [nTPM]":"24.3","Cell RNA - HaCaT [nTPM]":"13.3","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"39.0","Cell RNA - HBF TERT88 [nTPM]":"25.2","Cell RNA - HDLM-2 [nTPM]":"12.0","Cell RNA - HEK 293 [nTPM]":"10.1","Cell RNA - HEL [nTPM]":"5.4","Cell RNA - HeLa [nTPM]":"18.9","Cell RNA - Hep G2 [nTPM]":"26.2","Cell RNA - HHSteC [nTPM]":"30.0","Cell RNA - HL-60 [nTPM]":"6.1","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"56.6","Cell RNA - hTCEpi [nTPM]":"43.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.2","Cell RNA - hTERT-HME1 [nTPM]":"5.3","Cell RNA - hTERT-RPE1 [nTPM]":"117.9","Cell RNA - HUVEC TERT2 [nTPM]":"44.8","Cell RNA - JURKAT [nTPM]":"8.9","Cell RNA - K-562 [nTPM]":"9.1","Cell RNA - Karpas-707 [nTPM]":"8.4","Cell RNA - LHCN-M2 [nTPM]":"45.8","Cell RNA - MCF7 [nTPM]":"40.2","Cell RNA - MOLT-4 [nTPM]":"3.4","Cell RNA - NB-4 [nTPM]":"9.1","Cell RNA - NTERA-2 [nTPM]":"12.0","Cell RNA - OE19 [nTPM]":"22.8","Cell RNA - PC-3 [nTPM]":"23.4","Cell RNA - REH [nTPM]":"6.3","Cell RNA - RH-30 [nTPM]":"17.0","Cell RNA - RPMI-8226 [nTPM]":"16.0","Cell RNA - RPTEC TERT1 [nTPM]":"86.6","Cell RNA - RT4 [nTPM]":"28.0","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"12.6","Cell RNA - SiHa [nTPM]":"24.6","Cell RNA - SK-BR-3 [nTPM]":"56.8","Cell RNA - SK-MEL-30 [nTPM]":"20.4","Cell RNA - SuSa [nTPM]":"19.5","Cell RNA - T-47d [nTPM]":"75.7","Cell RNA - THP-1 [nTPM]":"15.6","Cell RNA - TIME [nTPM]":"41.4","Cell RNA - U-138 MG [nTPM]":"32.5","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"25.3","Cell RNA - U-251 MG [nTPM]":"21.0","Cell RNA - U-266\/70 [nTPM]":"10.4","Cell RNA - U-266\/84 [nTPM]":"22.8","Cell RNA - U-698 [nTPM]":"1.7","Cell RNA - U-87 MG [nTPM]":"63.2","Cell RNA - U-937 [nTPM]":"13.5","Cell RNA - WM-115 [nTPM]":"24.7","Blood RNA - basophil [nTPM]":"66.1","Blood RNA - classical monocyte [nTPM]":"100.5","Blood RNA - eosinophil [nTPM]":"35.6","Blood RNA - gdT-cell [nTPM]":"38.9","Blood RNA - intermediate monocyte [nTPM]":"81.8","Blood RNA - MAIT T-cell [nTPM]":"35.2","Blood RNA - memory B-cell [nTPM]":"26.6","Blood RNA - memory CD4 T-cell [nTPM]":"31.2","Blood RNA - memory CD8 T-cell [nTPM]":"32.9","Blood RNA - myeloid DC [nTPM]":"86.6","Blood RNA - naive B-cell [nTPM]":"30.7","Blood RNA - naive CD4 T-cell [nTPM]":"39.4","Blood RNA - naive CD8 T-cell [nTPM]":"32.0","Blood RNA - neutrophil [nTPM]":"36.2","Blood RNA - NK-cell [nTPM]":"42.0","Blood RNA - non-classical monocyte [nTPM]":"78.2","Blood RNA - plasmacytoid DC [nTPM]":"45.9","Blood RNA - T-reg [nTPM]":"16.9","Blood RNA - total PBMC [nTPM]":"90.2","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"12.0","Brain RNA - cerebellum [nTPM]":"10.9","Brain RNA - cerebral cortex [nTPM]":"12.2","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"12.2","Brain RNA - midbrain [nTPM]":"11.7","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"13.1","Brain RNA - white matter [nTPM]":"13.1","Single Cell Type RNA - Adipocytes [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.1","Single Cell Type RNA - Astrocytes [nTPM]":"36.9","Single Cell Type RNA - B-cells [nTPM]":"13.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"5.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"16.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.8","Single Cell Type RNA - dendritic cells [nTPM]":"9.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"39.3","Single Cell Type RNA - Early spermatids [nTPM]":"26.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.1","Single Cell Type RNA - Endothelial cells [nTPM]":"13.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"11.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.3","Single Cell Type RNA - Fibroblasts [nTPM]":"25.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.9","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"10.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"18.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"57.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"37.1","Single Cell Type RNA - Langerhans cells [nTPM]":"12.0","Single Cell Type RNA - Late spermatids [nTPM]":"10.7","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"24.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"62.8","Single Cell Type RNA - monocytes [nTPM]":"43.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.8","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"56.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"85.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.0","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"17.3","Single Cell Type RNA - Plasma cells [nTPM]":"11.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.5","Single Cell Type RNA - Spermatocytes [nTPM]":"4.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.4","Single Cell Type RNA - T-cells [nTPM]":"11.6","Single Cell Type RNA - Theca cells [nTPM]":"11.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.6","Single Cell Type RNA - Urothelial cells [nTPM]":"18.3"},{"Gene":"TPP1","Gene synonym":["CLN2","LPIC","SCAR7","TPP-1"],"Ensembl":"ENSG00000166340","Gene description":"Tripeptidyl peptidase 1","Uniprot":["O14773"],"Chromosome":"11","Position":"6612768-6619448","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Neuronal ceroid lipofuscinosis","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"261.6","Kupffer cells":"376.5","Macrophages":"219.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037709","HPA044868"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9500000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037709":"AB_10672913","HPA044868":"AB_2679122"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.31e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.46e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"74.7","Tissue RNA - adrenal gland [nTPM]":"145.9","Tissue RNA - amygdala [nTPM]":"71.0","Tissue RNA - appendix [nTPM]":"74.6","Tissue RNA - basal ganglia [nTPM]":"81.0","Tissue RNA - bone marrow [nTPM]":"111.7","Tissue RNA - breast [nTPM]":"44.3","Tissue RNA - cerebellum [nTPM]":"80.3","Tissue RNA - cerebral cortex [nTPM]":"81.4","Tissue RNA - cervix [nTPM]":"53.8","Tissue RNA - choroid plexus [nTPM]":"120.1","Tissue RNA - colon [nTPM]":"59.1","Tissue RNA - duodenum [nTPM]":"59.9","Tissue RNA - endometrium 1 [nTPM]":"74.0","Tissue RNA - epididymis [nTPM]":"43.1","Tissue RNA - esophagus [nTPM]":"39.5","Tissue RNA - fallopian tube [nTPM]":"47.1","Tissue RNA - gallbladder [nTPM]":"65.1","Tissue RNA - heart muscle [nTPM]":"56.3","Tissue RNA - hippocampal formation [nTPM]":"70.6","Tissue RNA - hypothalamus [nTPM]":"78.4","Tissue RNA - kidney [nTPM]":"71.6","Tissue RNA - liver [nTPM]":"92.7","Tissue RNA - lung [nTPM]":"81.5","Tissue RNA - lymph node [nTPM]":"77.7","Tissue RNA - medulla oblongata [nTPM]":"85.2","Tissue RNA - midbrain [nTPM]":"82.6","Tissue RNA - ovary [nTPM]":"49.7","Tissue RNA - pancreas [nTPM]":"36.2","Tissue RNA - parathyroid gland [nTPM]":"54.2","Tissue RNA - pituitary gland [nTPM]":"63.6","Tissue RNA - placenta [nTPM]":"94.2","Tissue RNA - pons [nTPM]":"81.0","Tissue RNA - prostate [nTPM]":"38.9","Tissue RNA - rectum [nTPM]":"59.7","Tissue RNA - retina [nTPM]":"48.5","Tissue RNA - salivary gland [nTPM]":"42.5","Tissue RNA - seminal vesicle [nTPM]":"57.5","Tissue RNA - skeletal muscle [nTPM]":"31.4","Tissue RNA - skin 1 [nTPM]":"39.5","Tissue RNA - small intestine [nTPM]":"73.3","Tissue RNA - smooth muscle [nTPM]":"92.0","Tissue RNA - spinal cord [nTPM]":"74.7","Tissue RNA - spleen [nTPM]":"135.0","Tissue RNA - stomach 1 [nTPM]":"48.4","Tissue RNA - testis [nTPM]":"20.0","Tissue RNA - thalamus [nTPM]":"83.3","Tissue RNA - thymus [nTPM]":"47.4","Tissue RNA - thyroid gland [nTPM]":"45.7","Tissue RNA - tongue [nTPM]":"39.0","Tissue RNA - tonsil [nTPM]":"60.9","Tissue RNA - urinary bladder [nTPM]":"68.4","Tissue RNA - vagina [nTPM]":"42.8","Tissue RNA - white matter [nTPM]":"90.4","Cell RNA - A-431 [nTPM]":"26.1","Cell RNA - A549 [nTPM]":"48.1","Cell RNA - AF22 [nTPM]":"25.9","Cell RNA - AN3-CA [nTPM]":"50.5","Cell RNA - ASC diff [nTPM]":"309.9","Cell RNA - ASC TERT1 [nTPM]":"160.1","Cell RNA - BEWO [nTPM]":"21.8","Cell RNA - BJ [nTPM]":"50.9","Cell RNA - BJ hTERT+ [nTPM]":"220.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"36.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.0","Cell RNA - CACO-2 [nTPM]":"20.1","Cell RNA - CAPAN-2 [nTPM]":"122.5","Cell RNA - Daudi [nTPM]":"37.4","Cell RNA - EFO-21 [nTPM]":"32.6","Cell RNA - fHDF\/TERT166 [nTPM]":"136.6","Cell RNA - GAMG [nTPM]":"220.2","Cell RNA - HaCaT [nTPM]":"85.8","Cell RNA - HAP1 [nTPM]":"48.3","Cell RNA - HBEC3-KT [nTPM]":"68.7","Cell RNA - HBF TERT88 [nTPM]":"57.9","Cell RNA - HDLM-2 [nTPM]":"37.3","Cell RNA - HEK 293 [nTPM]":"27.6","Cell RNA - HEL [nTPM]":"32.2","Cell RNA - HeLa [nTPM]":"23.8","Cell RNA - Hep G2 [nTPM]":"54.9","Cell RNA - HHSteC [nTPM]":"210.9","Cell RNA - HL-60 [nTPM]":"45.8","Cell RNA - HMC-1 [nTPM]":"182.6","Cell RNA - HSkMC [nTPM]":"231.8","Cell RNA - hTCEpi [nTPM]":"104.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"45.9","Cell RNA - hTERT-HME1 [nTPM]":"102.6","Cell RNA - hTERT-RPE1 [nTPM]":"240.4","Cell RNA - HUVEC TERT2 [nTPM]":"158.8","Cell RNA - JURKAT [nTPM]":"32.9","Cell RNA - K-562 [nTPM]":"59.8","Cell RNA - Karpas-707 [nTPM]":"124.6","Cell RNA - LHCN-M2 [nTPM]":"110.4","Cell RNA - MCF7 [nTPM]":"30.2","Cell RNA - MOLT-4 [nTPM]":"16.6","Cell RNA - NB-4 [nTPM]":"52.4","Cell RNA - NTERA-2 [nTPM]":"18.0","Cell RNA - OE19 [nTPM]":"61.5","Cell RNA - PC-3 [nTPM]":"57.1","Cell RNA - REH [nTPM]":"36.1","Cell RNA - RH-30 [nTPM]":"21.6","Cell RNA - RPMI-8226 [nTPM]":"77.0","Cell RNA - RPTEC TERT1 [nTPM]":"62.8","Cell RNA - RT4 [nTPM]":"38.2","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"20.4","Cell RNA - SiHa [nTPM]":"52.6","Cell RNA - SK-BR-3 [nTPM]":"44.6","Cell RNA - SK-MEL-30 [nTPM]":"91.0","Cell RNA - SuSa [nTPM]":"76.5","Cell RNA - T-47d [nTPM]":"30.8","Cell RNA - THP-1 [nTPM]":"79.7","Cell RNA - TIME [nTPM]":"188.0","Cell RNA - U-138 MG [nTPM]":"119.7","Cell RNA - U-2 OS [nTPM]":"33.1","Cell RNA - U-2197 [nTPM]":"101.1","Cell RNA - U-251 MG [nTPM]":"19.8","Cell RNA - U-266\/70 [nTPM]":"92.3","Cell RNA - U-266\/84 [nTPM]":"95.3","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"139.8","Cell RNA - U-937 [nTPM]":"101.7","Cell RNA - WM-115 [nTPM]":"64.5","Blood RNA - basophil [nTPM]":"67.0","Blood RNA - classical monocyte [nTPM]":"167.1","Blood RNA - eosinophil [nTPM]":"38.2","Blood RNA - gdT-cell [nTPM]":"39.9","Blood RNA - intermediate monocyte [nTPM]":"171.2","Blood RNA - MAIT T-cell [nTPM]":"30.0","Blood RNA - memory B-cell [nTPM]":"35.1","Blood RNA - memory CD4 T-cell [nTPM]":"31.4","Blood RNA - memory CD8 T-cell [nTPM]":"41.0","Blood RNA - myeloid DC [nTPM]":"185.9","Blood RNA - naive B-cell [nTPM]":"37.0","Blood RNA - naive CD4 T-cell [nTPM]":"20.1","Blood RNA - naive CD8 T-cell [nTPM]":"27.2","Blood RNA - neutrophil [nTPM]":"27.5","Blood RNA - NK-cell [nTPM]":"29.1","Blood RNA - non-classical monocyte [nTPM]":"125.1","Blood RNA - plasmacytoid DC [nTPM]":"93.1","Blood RNA - T-reg [nTPM]":"60.3","Blood RNA - total PBMC [nTPM]":"138.8","Brain RNA - amygdala [nTPM]":"71.0","Brain RNA - basal ganglia [nTPM]":"81.0","Brain RNA - cerebellum [nTPM]":"80.3","Brain RNA - cerebral cortex [nTPM]":"81.4","Brain RNA - hippocampal formation [nTPM]":"70.6","Brain RNA - hypothalamus [nTPM]":"78.4","Brain RNA - medulla oblongata [nTPM]":"85.2","Brain RNA - midbrain [nTPM]":"82.6","Brain RNA - pons [nTPM]":"81.0","Brain RNA - spinal cord [nTPM]":"74.7","Brain RNA - thalamus [nTPM]":"83.3","Brain RNA - white matter [nTPM]":"90.4","Single Cell Type RNA - Adipocytes [nTPM]":"32.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.3","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"53.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"24.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"26.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.4","Single Cell Type RNA - dendritic cells [nTPM]":"71.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"55.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"42.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.2","Single Cell Type RNA - Endothelial cells [nTPM]":"40.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.7","Single Cell Type RNA - Erythroid cells [nTPM]":"37.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.3","Single Cell Type RNA - Fibroblasts [nTPM]":"40.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.8","Single Cell Type RNA - granulocytes [nTPM]":"62.2","Single Cell Type RNA - Granulosa cells [nTPM]":"25.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"75.7","Single Cell Type RNA - Hepatocytes [nTPM]":"81.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"261.6","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.3","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"376.5","Single Cell Type RNA - Langerhans cells [nTPM]":"126.5","Single Cell Type RNA - Late spermatids [nTPM]":"11.2","Single Cell Type RNA - Leydig cells [nTPM]":"27.1","Single Cell Type RNA - Macrophages [nTPM]":"219.8","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"156.0","Single Cell Type RNA - Muller glia cells [nTPM]":"37.9","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.4","Single Cell Type RNA - Paneth cells [nTPM]":"44.1","Single Cell Type RNA - Peritubular cells [nTPM]":"26.4","Single Cell Type RNA - Plasma cells [nTPM]":"26.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"99.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"51.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.0","Single Cell Type RNA - T-cells [nTPM]":"42.2","Single Cell Type RNA - Theca cells [nTPM]":"24.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.5","Single Cell Type RNA - Urothelial cells [nTPM]":"26.5"}]