[{"Gene":"CHEK2","Gene synonym":["bA444G7","CDS1","CHK2","HuCds1","PP1425","RAD53"],"Ensembl":"ENSG00000183765","Gene description":"Checkpoint kinase 2","Uniprot":["O96017"],"Chromosome":"22","Position":"28687743-28742422","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cell cycle","Cell division","DNA damage","DNA repair","Mitosis","Transcription","Transcription regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatogonia":"31.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001878","CAB002030"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB002030":"AB_563660","HPA001878":"AB_1078514"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.80e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.5","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"8.8","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"15.4","Tissue RNA - breast [nTPM]":"5.8","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"5.0","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"6.3","Tissue RNA - endometrium 1 [nTPM]":"4.1","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"4.7","Tissue RNA - heart muscle [nTPM]":"4.2","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"4.5","Tissue RNA - liver [nTPM]":"6.3","Tissue RNA - lung [nTPM]":"4.4","Tissue RNA - lymph node [nTPM]":"12.1","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"1.3","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"2.8","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"6.7","Tissue RNA - small intestine [nTPM]":"7.0","Tissue RNA - smooth muscle [nTPM]":"4.8","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"4.1","Tissue RNA - testis [nTPM]":"8.5","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"3.3","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"12.0","Tissue RNA - urinary bladder [nTPM]":"6.8","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"30.7","Cell RNA - A549 [nTPM]":"9.7","Cell RNA - AF22 [nTPM]":"31.1","Cell RNA - AN3-CA [nTPM]":"32.4","Cell RNA - ASC diff [nTPM]":"10.1","Cell RNA - ASC TERT1 [nTPM]":"42.7","Cell RNA - BEWO [nTPM]":"18.7","Cell RNA - BJ [nTPM]":"15.2","Cell RNA - BJ hTERT+ [nTPM]":"19.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.8","Cell RNA - CACO-2 [nTPM]":"29.1","Cell RNA - CAPAN-2 [nTPM]":"21.8","Cell RNA - Daudi [nTPM]":"36.3","Cell RNA - EFO-21 [nTPM]":"13.0","Cell RNA - fHDF\/TERT166 [nTPM]":"11.5","Cell RNA - GAMG [nTPM]":"21.6","Cell RNA - HaCaT [nTPM]":"32.1","Cell RNA - HAP1 [nTPM]":"42.7","Cell RNA - HBEC3-KT [nTPM]":"29.0","Cell RNA - HBF TERT88 [nTPM]":"25.0","Cell RNA - HDLM-2 [nTPM]":"24.6","Cell RNA - HEK 293 [nTPM]":"31.2","Cell RNA - HEL [nTPM]":"45.3","Cell RNA - HeLa [nTPM]":"25.5","Cell RNA - Hep G2 [nTPM]":"46.2","Cell RNA - HHSteC [nTPM]":"9.4","Cell RNA - HL-60 [nTPM]":"33.4","Cell RNA - HMC-1 [nTPM]":"38.0","Cell RNA - HSkMC [nTPM]":"18.6","Cell RNA - hTCEpi [nTPM]":"13.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.0","Cell RNA - hTERT-HME1 [nTPM]":"23.0","Cell RNA - hTERT-RPE1 [nTPM]":"14.1","Cell RNA - HUVEC TERT2 [nTPM]":"25.4","Cell RNA - JURKAT [nTPM]":"29.4","Cell RNA - K-562 [nTPM]":"30.5","Cell RNA - Karpas-707 [nTPM]":"33.9","Cell RNA - LHCN-M2 [nTPM]":"19.8","Cell RNA - MCF7 [nTPM]":"39.2","Cell RNA - MOLT-4 [nTPM]":"24.6","Cell RNA - NB-4 [nTPM]":"61.5","Cell RNA - NTERA-2 [nTPM]":"40.6","Cell RNA - OE19 [nTPM]":"41.3","Cell RNA - PC-3 [nTPM]":"21.6","Cell RNA - REH [nTPM]":"52.6","Cell RNA - RH-30 [nTPM]":"18.2","Cell RNA - RPMI-8226 [nTPM]":"42.7","Cell RNA - RPTEC TERT1 [nTPM]":"17.1","Cell RNA - RT4 [nTPM]":"11.2","Cell RNA - SCLC-21H [nTPM]":"17.8","Cell RNA - SH-SY5Y [nTPM]":"9.7","Cell RNA - SiHa [nTPM]":"16.7","Cell RNA - SK-BR-3 [nTPM]":"31.4","Cell RNA - SK-MEL-30 [nTPM]":"17.4","Cell RNA - SuSa [nTPM]":"22.8","Cell RNA - T-47d [nTPM]":"22.6","Cell RNA - THP-1 [nTPM]":"32.2","Cell RNA - TIME [nTPM]":"7.8","Cell RNA - U-138 MG [nTPM]":"17.1","Cell RNA - U-2 OS [nTPM]":"19.4","Cell RNA - U-2197 [nTPM]":"14.3","Cell RNA - U-251 MG [nTPM]":"9.1","Cell RNA - U-266\/70 [nTPM]":"21.8","Cell RNA - U-266\/84 [nTPM]":"28.3","Cell RNA - U-698 [nTPM]":"65.4","Cell RNA - U-87 MG [nTPM]":"17.1","Cell RNA - U-937 [nTPM]":"34.9","Cell RNA - WM-115 [nTPM]":"21.0","Blood RNA - basophil [nTPM]":"9.9","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"8.1","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"11.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"8.2","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"3.4","Blood RNA - non-classical monocyte [nTPM]":"4.1","Blood RNA - plasmacytoid DC [nTPM]":"6.1","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.8","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"2.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"5.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"7.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.6","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.0","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"7.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.4","Single Cell Type RNA - Langerhans cells [nTPM]":"8.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"4.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"11.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.0","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"31.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"CHRM3","Gene synonym":[],"Ensembl":"ENSG00000133019","Gene description":"Cholinergic receptor muscarinic 3","Uniprot":["P20309"],"Chromosome":"1","Position":"239386565-239915452","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.8","salivary gland":"17.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"28","RNA single cell type specific nTPM":{"Excitatory neurons":"802.9","Inhibitory neurons":"624.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPMI-8226":"17.2","SH-SY5Y":"53.5","U-266\/70":"21.7","U-266\/84":"16.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024106","HPA048036"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA024106":"AB_1854211","HPA048036":"AB_2680238"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"7.3","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"11.8","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"7.5","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.1","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"10.6","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"17.5","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"1.5","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"2.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"7.0","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"5.8","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"3.8","Cell RNA - HBF TERT88 [nTPM]":"2.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"3.7","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.1","Cell RNA - Karpas-707 [nTPM]":"9.1","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"4.6","Cell RNA - PC-3 [nTPM]":"9.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"17.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"53.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"4.0","Cell RNA - T-47d [nTPM]":"1.8","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"2.3","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"21.7","Cell RNA - U-266\/84 [nTPM]":"16.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"7.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"11.8","Brain RNA - hippocampal formation [nTPM]":"7.5","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"6.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"19.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"19.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"802.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"624.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.6","Single Cell Type RNA - Paneth cells [nTPM]":"25.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"12.9","Single Cell Type RNA - Spermatogonia [nTPM]":"3.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"EDNRB","Gene synonym":["ETB","HSCR","HSCR2"],"Ensembl":"ENSG00000136160","Gene description":"Endothelin receptor type B","Uniprot":["P24530"],"Chromosome":"13","Position":"77895481-77975529","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Albinism","Deafness","Disease variant","FDA approved drug targets","Hirschsprung disease","Waardenburg syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"127.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"120.5","Astrocytes":"126.3","Hepatic stellate cells":"112.5","Melanocytes":"110.3","Muller glia cells":"116.2","Sertoli cells":"216.9","Skeletal myocytes":"81.3","Smooth muscle cells":"102.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"127.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"68.0","ASC diff":"50.5","SK-MEL-30":"66.0","U-266\/70":"40.7","WM-115":"131.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017842","HPA027546"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB017842":null,"HPA027546":"AB_2672327"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.20e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-3"},"Tissue RNA - adipose tissue [nTPM]":"58.8","Tissue RNA - adrenal gland [nTPM]":"41.2","Tissue RNA - amygdala [nTPM]":"34.7","Tissue RNA - appendix [nTPM]":"19.5","Tissue RNA - basal ganglia [nTPM]":"50.8","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"39.8","Tissue RNA - cerebellum [nTPM]":"44.6","Tissue RNA - cerebral cortex [nTPM]":"26.1","Tissue RNA - cervix [nTPM]":"18.7","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"20.0","Tissue RNA - endometrium 1 [nTPM]":"13.1","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"8.2","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"14.9","Tissue RNA - heart muscle [nTPM]":"28.1","Tissue RNA - hippocampal formation [nTPM]":"27.5","Tissue RNA - hypothalamus [nTPM]":"51.6","Tissue RNA - kidney [nTPM]":"33.0","Tissue RNA - liver [nTPM]":"50.9","Tissue RNA - lung [nTPM]":"51.2","Tissue RNA - lymph node [nTPM]":"10.4","Tissue RNA - medulla oblongata [nTPM]":"76.2","Tissue RNA - midbrain [nTPM]":"66.0","Tissue RNA - ovary [nTPM]":"4.7","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"15.3","Tissue RNA - pituitary gland [nTPM]":"9.6","Tissue RNA - placenta [nTPM]":"127.8","Tissue RNA - pons [nTPM]":"47.9","Tissue RNA - prostate [nTPM]":"25.3","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"17.9","Tissue RNA - salivary gland [nTPM]":"27.0","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"11.3","Tissue RNA - skin 1 [nTPM]":"12.5","Tissue RNA - small intestine [nTPM]":"21.9","Tissue RNA - smooth muscle [nTPM]":"12.9","Tissue RNA - spinal cord [nTPM]":"97.2","Tissue RNA - spleen [nTPM]":"16.8","Tissue RNA - stomach 1 [nTPM]":"10.6","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"64.9","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"31.8","Tissue RNA - tongue [nTPM]":"18.8","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"15.5","Tissue RNA - white matter [nTPM]":"78.7","Cell RNA - A-431 [nTPM]":"5.7","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"68.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"50.5","Cell RNA - ASC TERT1 [nTPM]":"2.0","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"25.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"13.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"66.0","Cell RNA - SuSa [nTPM]":"8.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"40.7","Cell RNA - U-266\/84 [nTPM]":"24.9","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"131.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"34.7","Brain RNA - basal ganglia [nTPM]":"50.8","Brain RNA - cerebellum [nTPM]":"44.6","Brain RNA - cerebral cortex [nTPM]":"26.1","Brain RNA - hippocampal formation [nTPM]":"27.5","Brain RNA - hypothalamus [nTPM]":"51.6","Brain RNA - medulla oblongata [nTPM]":"76.2","Brain RNA - midbrain [nTPM]":"66.0","Brain RNA - pons [nTPM]":"47.9","Brain RNA - spinal cord [nTPM]":"97.2","Brain RNA - thalamus [nTPM]":"64.9","Brain RNA - white matter [nTPM]":"78.7","Single Cell Type RNA - Adipocytes [nTPM]":"120.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.0","Single Cell Type RNA - Astrocytes [nTPM]":"126.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.7","Single Cell Type RNA - Endothelial cells [nTPM]":"73.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.9","Single Cell Type RNA - Fibroblasts [nTPM]":"51.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.9","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"112.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"18.7","Single Cell Type RNA - Langerhans cells [nTPM]":"10.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"79.9","Single Cell Type RNA - Macrophages [nTPM]":"5.2","Single Cell Type RNA - Melanocytes [nTPM]":"110.3","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"116.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.4","Single Cell Type RNA - Sertoli cells [nTPM]":"216.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"81.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"102.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.7","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"2.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"EPCAM","Gene synonym":["17-1A","323\/A3","CD326","CO-17A","EGP-2","EGP34","EGP40","Ep-CAM","ESA","GA733-2","HEA125","KS1\/4","KSA","Ly74","M4S1","MH99","MIC18","MK-1","MOC31","TACST-1","TACSTD1","TROP1"],"Ensembl":"ENSG00000119888","Gene description":"Epithelial cell adhesion molecule","Uniprot":["P16422"],"Chromosome":"2","Position":"47345158-47387601","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Tumor antigen"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Hereditary nonpolyposis colorectal cancer"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"806.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"2317.0","Ductal cells":"999.6","Intestinal goblet cells":"1378.2","Paneth cells":"2437.0","Proximal enterocytes":"2681.1","Undifferentiated cells":"1607.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"538.9","CACO-2":"680.9","CAPAN-2":"944.4","OE19":"911.8","RPTEC TERT1":"398.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003809","HPA026761","CAB030012","CAB055098","HPA067463"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"22000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB003809":"AB_562285","CAB030012":"AB_756075","CAB055098":"AB_2335685","HPA026761":"AB_1848198","HPA067463":"AB_2685846"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.30e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.4","Tissue RNA - adrenal gland [nTPM]":"12.2","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"77.0","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"10.2","Tissue RNA - breast [nTPM]":"99.7","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"116.2","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"806.0","Tissue RNA - duodenum [nTPM]":"726.5","Tissue RNA - endometrium 1 [nTPM]":"33.0","Tissue RNA - epididymis [nTPM]":"238.9","Tissue RNA - esophagus [nTPM]":"10.8","Tissue RNA - fallopian tube [nTPM]":"114.3","Tissue RNA - gallbladder [nTPM]":"71.1","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"223.1","Tissue RNA - liver [nTPM]":"3.1","Tissue RNA - lung [nTPM]":"74.7","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"125.4","Tissue RNA - parathyroid gland [nTPM]":"219.5","Tissue RNA - pituitary gland [nTPM]":"86.9","Tissue RNA - placenta [nTPM]":"1.7","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"60.5","Tissue RNA - rectum [nTPM]":"751.0","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"119.8","Tissue RNA - seminal vesicle [nTPM]":"52.8","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"8.8","Tissue RNA - small intestine [nTPM]":"769.6","Tissue RNA - smooth muscle [nTPM]":"22.2","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"172.4","Tissue RNA - testis [nTPM]":"21.7","Tissue RNA - thalamus [nTPM]":"10.4","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"286.8","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"30.9","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"538.9","Cell RNA - A549 [nTPM]":"5.4","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"1.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"321.3","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"680.9","Cell RNA - CAPAN-2 [nTPM]":"944.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"141.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"247.3","Cell RNA - HAP1 [nTPM]":"4.6","Cell RNA - HBEC3-KT [nTPM]":"62.2","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"56.3","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"261.6","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"17.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.8","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"160.9","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"269.7","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"24.0","Cell RNA - NTERA-2 [nTPM]":"164.3","Cell RNA - OE19 [nTPM]":"911.8","Cell RNA - PC-3 [nTPM]":"31.4","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"136.9","Cell RNA - RPTEC TERT1 [nTPM]":"398.6","Cell RNA - RT4 [nTPM]":"231.3","Cell RNA - SCLC-21H [nTPM]":"354.0","Cell RNA - SH-SY5Y [nTPM]":"3.2","Cell RNA - SiHa [nTPM]":"4.3","Cell RNA - SK-BR-3 [nTPM]":"187.7","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"132.7","Cell RNA - T-47d [nTPM]":"158.3","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"6.3","Cell RNA - U-2197 [nTPM]":"2.0","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"39.2","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"10.4","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"3.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"310.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"148.1","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"7.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"227.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"127.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"184.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"112.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"243.1","Single Cell Type RNA - Club cells [nTPM]":"222.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"448.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.4","Single Cell Type RNA - dendritic cells [nTPM]":"2.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"2317.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"76.3","Single Cell Type RNA - Ductal cells [nTPM]":"999.6","Single Cell Type RNA - Early spermatids [nTPM]":"8.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"434.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.3","Single Cell Type RNA - Endothelial cells [nTPM]":"5.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"498.1","Single Cell Type RNA - Erythroid cells [nTPM]":"23.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"402.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.5","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"150.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"445.3","Single Cell Type RNA - granulocytes [nTPM]":"32.5","Single Cell Type RNA - Granulosa cells [nTPM]":"11.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1378.2","Single Cell Type RNA - Ionocytes [nTPM]":"486.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.2","Single Cell Type RNA - Late spermatids [nTPM]":"5.6","Single Cell Type RNA - Leydig cells [nTPM]":"20.5","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"11.5","Single Cell Type RNA - Muller glia cells [nTPM]":"15.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"617.5","Single Cell Type RNA - Paneth cells [nTPM]":"2437.0","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"1.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"257.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2681.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"195.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"219.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.7","Single Cell Type RNA - Spermatocytes [nTPM]":"83.5","Single Cell Type RNA - Spermatogonia [nTPM]":"130.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - T-cells [nTPM]":"9.4","Single Cell Type RNA - Theca cells [nTPM]":"70.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1607.7","Single Cell Type RNA - Urothelial cells [nTPM]":"230.7"},{"Gene":"FH","Gene synonym":[],"Ensembl":"ENSG00000091483","Gene description":"Fumarate hydratase","Uniprot":["P07954"],"Chromosome":"1","Position":"241497603-241519755","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Tricarboxylic acid cycle"],"Molecular function":["Lyase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"276.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"173.5","Early spermatids":"226.0","Syncytiotrophoblasts":"166.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017785","HPA025770","HPA025948","HPA027341"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB017785":null,"HPA025770":"AB_10599603","HPA025948":"AB_10602177","HPA027341":"AB_10601222"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"43.4","Tissue RNA - adrenal gland [nTPM]":"75.2","Tissue RNA - amygdala [nTPM]":"30.4","Tissue RNA - appendix [nTPM]":"31.0","Tissue RNA - basal ganglia [nTPM]":"33.3","Tissue RNA - bone marrow [nTPM]":"31.4","Tissue RNA - breast [nTPM]":"37.3","Tissue RNA - cerebellum [nTPM]":"33.5","Tissue RNA - cerebral cortex [nTPM]":"42.0","Tissue RNA - cervix [nTPM]":"28.9","Tissue RNA - choroid plexus [nTPM]":"43.9","Tissue RNA - colon [nTPM]":"66.8","Tissue RNA - duodenum [nTPM]":"68.2","Tissue RNA - endometrium 1 [nTPM]":"36.9","Tissue RNA - epididymis [nTPM]":"26.1","Tissue RNA - esophagus [nTPM]":"51.1","Tissue RNA - fallopian tube [nTPM]":"27.9","Tissue RNA - gallbladder [nTPM]":"23.7","Tissue RNA - heart muscle [nTPM]":"179.0","Tissue RNA - hippocampal formation [nTPM]":"33.9","Tissue RNA - hypothalamus [nTPM]":"33.1","Tissue RNA - kidney [nTPM]":"101.8","Tissue RNA - liver [nTPM]":"276.4","Tissue RNA - lung [nTPM]":"26.4","Tissue RNA - lymph node [nTPM]":"30.0","Tissue RNA - medulla oblongata [nTPM]":"31.8","Tissue RNA - midbrain [nTPM]":"31.0","Tissue RNA - ovary [nTPM]":"24.9","Tissue RNA - pancreas [nTPM]":"38.1","Tissue RNA - parathyroid gland [nTPM]":"95.0","Tissue RNA - pituitary gland [nTPM]":"31.1","Tissue RNA - placenta [nTPM]":"32.1","Tissue RNA - pons [nTPM]":"32.1","Tissue RNA - prostate [nTPM]":"33.5","Tissue RNA - rectum [nTPM]":"69.0","Tissue RNA - retina [nTPM]":"58.8","Tissue RNA - salivary gland [nTPM]":"42.0","Tissue RNA - seminal vesicle [nTPM]":"38.4","Tissue RNA - skeletal muscle [nTPM]":"213.4","Tissue RNA - skin 1 [nTPM]":"40.3","Tissue RNA - small intestine [nTPM]":"59.1","Tissue RNA - smooth muscle [nTPM]":"42.0","Tissue RNA - spinal cord [nTPM]":"32.4","Tissue RNA - spleen [nTPM]":"30.1","Tissue RNA - stomach 1 [nTPM]":"53.6","Tissue RNA - testis [nTPM]":"44.4","Tissue RNA - thalamus [nTPM]":"32.7","Tissue RNA - thymus [nTPM]":"31.3","Tissue RNA - thyroid gland [nTPM]":"34.6","Tissue RNA - tongue [nTPM]":"229.3","Tissue RNA - tonsil [nTPM]":"40.4","Tissue RNA - urinary bladder [nTPM]":"37.5","Tissue RNA - vagina [nTPM]":"33.7","Tissue RNA - white matter [nTPM]":"33.0","Cell RNA - A-431 [nTPM]":"129.2","Cell RNA - A549 [nTPM]":"105.6","Cell RNA - AF22 [nTPM]":"97.9","Cell RNA - AN3-CA [nTPM]":"89.0","Cell RNA - ASC diff [nTPM]":"93.9","Cell RNA - ASC TERT1 [nTPM]":"110.0","Cell RNA - BEWO [nTPM]":"154.9","Cell RNA - BJ [nTPM]":"155.7","Cell RNA - BJ hTERT+ [nTPM]":"121.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"171.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"107.1","Cell RNA - CACO-2 [nTPM]":"152.2","Cell RNA - CAPAN-2 [nTPM]":"78.0","Cell RNA - Daudi [nTPM]":"81.1","Cell RNA - EFO-21 [nTPM]":"100.3","Cell RNA - fHDF\/TERT166 [nTPM]":"119.9","Cell RNA - GAMG [nTPM]":"75.0","Cell RNA - HaCaT [nTPM]":"178.4","Cell RNA - HAP1 [nTPM]":"151.7","Cell RNA - HBEC3-KT [nTPM]":"115.8","Cell RNA - HBF TERT88 [nTPM]":"148.4","Cell RNA - HDLM-2 [nTPM]":"93.5","Cell RNA - HEK 293 [nTPM]":"48.9","Cell RNA - HEL [nTPM]":"76.3","Cell RNA - HeLa [nTPM]":"102.2","Cell RNA - Hep G2 [nTPM]":"131.4","Cell RNA - HHSteC [nTPM]":"84.1","Cell RNA - HL-60 [nTPM]":"180.2","Cell RNA - HMC-1 [nTPM]":"66.7","Cell RNA - HSkMC [nTPM]":"80.2","Cell RNA - hTCEpi [nTPM]":"70.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"96.6","Cell RNA - hTERT-HME1 [nTPM]":"108.0","Cell RNA - hTERT-RPE1 [nTPM]":"60.2","Cell RNA - HUVEC TERT2 [nTPM]":"107.2","Cell RNA - JURKAT [nTPM]":"175.8","Cell RNA - K-562 [nTPM]":"236.3","Cell RNA - Karpas-707 [nTPM]":"101.7","Cell RNA - LHCN-M2 [nTPM]":"126.9","Cell RNA - MCF7 [nTPM]":"64.3","Cell RNA - MOLT-4 [nTPM]":"156.6","Cell RNA - NB-4 [nTPM]":"120.1","Cell RNA - NTERA-2 [nTPM]":"104.5","Cell RNA - OE19 [nTPM]":"186.2","Cell RNA - PC-3 [nTPM]":"223.6","Cell RNA - REH [nTPM]":"127.4","Cell RNA - RH-30 [nTPM]":"107.2","Cell RNA - RPMI-8226 [nTPM]":"365.7","Cell RNA - RPTEC TERT1 [nTPM]":"167.4","Cell RNA - RT4 [nTPM]":"107.6","Cell RNA - SCLC-21H [nTPM]":"125.4","Cell RNA - SH-SY5Y [nTPM]":"108.4","Cell RNA - SiHa [nTPM]":"131.1","Cell RNA - SK-BR-3 [nTPM]":"153.3","Cell RNA - SK-MEL-30 [nTPM]":"104.0","Cell RNA - SuSa [nTPM]":"67.2","Cell RNA - T-47d [nTPM]":"117.1","Cell RNA - THP-1 [nTPM]":"120.9","Cell RNA - TIME [nTPM]":"106.5","Cell RNA - U-138 MG [nTPM]":"76.6","Cell RNA - U-2 OS [nTPM]":"98.9","Cell RNA - U-2197 [nTPM]":"137.0","Cell RNA - U-251 MG [nTPM]":"264.0","Cell RNA - U-266\/70 [nTPM]":"90.3","Cell RNA - U-266\/84 [nTPM]":"103.7","Cell RNA - U-698 [nTPM]":"97.3","Cell RNA - U-87 MG [nTPM]":"85.7","Cell RNA - U-937 [nTPM]":"203.5","Cell RNA - WM-115 [nTPM]":"112.6","Blood RNA - basophil [nTPM]":"11.9","Blood RNA - classical monocyte [nTPM]":"22.8","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"16.1","Blood RNA - intermediate monocyte [nTPM]":"33.3","Blood RNA - MAIT T-cell [nTPM]":"21.0","Blood RNA - memory B-cell [nTPM]":"27.2","Blood RNA - memory CD4 T-cell [nTPM]":"18.8","Blood RNA - memory CD8 T-cell [nTPM]":"15.1","Blood RNA - myeloid DC [nTPM]":"46.7","Blood RNA - naive B-cell [nTPM]":"25.1","Blood RNA - naive CD4 T-cell [nTPM]":"22.3","Blood RNA - naive CD8 T-cell [nTPM]":"21.1","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"18.3","Blood RNA - non-classical monocyte [nTPM]":"29.1","Blood RNA - plasmacytoid DC [nTPM]":"23.1","Blood RNA - T-reg [nTPM]":"23.8","Blood RNA - total PBMC [nTPM]":"16.7","Brain RNA - amygdala [nTPM]":"30.4","Brain RNA - basal ganglia [nTPM]":"33.3","Brain RNA - cerebellum [nTPM]":"33.5","Brain RNA - cerebral cortex [nTPM]":"42.0","Brain RNA - hippocampal formation [nTPM]":"33.9","Brain RNA - hypothalamus [nTPM]":"33.1","Brain RNA - medulla oblongata [nTPM]":"31.8","Brain RNA - midbrain [nTPM]":"31.0","Brain RNA - pons [nTPM]":"32.1","Brain RNA - spinal cord [nTPM]":"32.4","Brain RNA - thalamus [nTPM]":"32.7","Brain RNA - white matter [nTPM]":"33.0","Single Cell Type RNA - Adipocytes [nTPM]":"17.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.2","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"25.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"69.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"24.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"173.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"40.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"101.6","Single Cell Type RNA - dendritic cells [nTPM]":"13.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"78.2","Single Cell Type RNA - Ductal cells [nTPM]":"60.4","Single Cell Type RNA - Early spermatids [nTPM]":"226.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.5","Single Cell Type RNA - Endothelial cells [nTPM]":"18.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"37.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"45.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.7","Single Cell Type RNA - Fibroblasts [nTPM]":"25.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.4","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"80.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"50.7","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.6","Single Cell Type RNA - Ionocytes [nTPM]":"48.8","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"14.4","Single Cell Type RNA - Late spermatids [nTPM]":"37.4","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"23.9","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"27.9","Single Cell Type RNA - Muller glia cells [nTPM]":"35.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.4","Single Cell Type RNA - Paneth cells [nTPM]":"35.7","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"41.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.1","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"67.9","Single Cell Type RNA - Spermatocytes [nTPM]":"84.7","Single Cell Type RNA - Spermatogonia [nTPM]":"47.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"166.1","Single Cell Type RNA - T-cells [nTPM]":"14.9","Single Cell Type RNA - Theca cells [nTPM]":"48.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"74.2","Single Cell Type RNA - Urothelial cells [nTPM]":"22.8"},{"Gene":"FLCN","Gene synonym":["BHD","DENND8B","MGC17998","MGC23445"],"Ensembl":"ENSG00000154803","Gene description":"Folliculin","Uniprot":["Q8NFG4"],"Chromosome":"17","Position":"17212212-17237188","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"79.2","Erythroid cells":"81.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015158","HPA028760"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB015158":"AB_2231645","HPA028760":"AB_10601323"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.49e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.8","Tissue RNA - adrenal gland [nTPM]":"19.0","Tissue RNA - amygdala [nTPM]":"19.0","Tissue RNA - appendix [nTPM]":"10.7","Tissue RNA - basal ganglia [nTPM]":"25.9","Tissue RNA - bone marrow [nTPM]":"17.7","Tissue RNA - breast [nTPM]":"18.9","Tissue RNA - cerebellum [nTPM]":"27.3","Tissue RNA - cerebral cortex [nTPM]":"31.6","Tissue RNA - cervix [nTPM]":"42.5","Tissue RNA - choroid plexus [nTPM]":"18.3","Tissue RNA - colon [nTPM]":"43.7","Tissue RNA - duodenum [nTPM]":"23.3","Tissue RNA - endometrium 1 [nTPM]":"37.0","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"13.8","Tissue RNA - fallopian tube [nTPM]":"25.2","Tissue RNA - gallbladder [nTPM]":"17.0","Tissue RNA - heart muscle [nTPM]":"29.2","Tissue RNA - hippocampal formation [nTPM]":"31.9","Tissue RNA - hypothalamus [nTPM]":"14.0","Tissue RNA - kidney [nTPM]":"15.3","Tissue RNA - liver [nTPM]":"28.9","Tissue RNA - lung [nTPM]":"26.8","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"21.3","Tissue RNA - midbrain [nTPM]":"15.2","Tissue RNA - ovary [nTPM]":"35.3","Tissue RNA - pancreas [nTPM]":"15.2","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"28.6","Tissue RNA - placenta [nTPM]":"13.1","Tissue RNA - pons [nTPM]":"22.0","Tissue RNA - prostate [nTPM]":"27.1","Tissue RNA - rectum [nTPM]":"10.2","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"16.4","Tissue RNA - seminal vesicle [nTPM]":"13.7","Tissue RNA - skeletal muscle [nTPM]":"42.7","Tissue RNA - skin 1 [nTPM]":"19.3","Tissue RNA - small intestine [nTPM]":"26.8","Tissue RNA - smooth muscle [nTPM]":"14.5","Tissue RNA - spinal cord [nTPM]":"14.0","Tissue RNA - spleen [nTPM]":"29.2","Tissue RNA - stomach 1 [nTPM]":"22.4","Tissue RNA - testis [nTPM]":"21.0","Tissue RNA - thalamus [nTPM]":"19.3","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"23.8","Tissue RNA - tongue [nTPM]":"18.4","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"28.2","Tissue RNA - vagina [nTPM]":"25.5","Tissue RNA - white matter [nTPM]":"28.3","Cell RNA - A-431 [nTPM]":"12.0","Cell RNA - A549 [nTPM]":"30.4","Cell RNA - AF22 [nTPM]":"11.5","Cell RNA - AN3-CA [nTPM]":"14.9","Cell RNA - ASC diff [nTPM]":"36.4","Cell RNA - ASC TERT1 [nTPM]":"20.6","Cell RNA - BEWO [nTPM]":"15.8","Cell RNA - BJ [nTPM]":"11.8","Cell RNA - BJ hTERT+ [nTPM]":"19.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.3","Cell RNA - CACO-2 [nTPM]":"24.3","Cell RNA - CAPAN-2 [nTPM]":"10.4","Cell RNA - Daudi [nTPM]":"6.3","Cell RNA - EFO-21 [nTPM]":"13.8","Cell RNA - fHDF\/TERT166 [nTPM]":"14.0","Cell RNA - GAMG [nTPM]":"40.2","Cell RNA - HaCaT [nTPM]":"14.4","Cell RNA - HAP1 [nTPM]":"14.0","Cell RNA - HBEC3-KT [nTPM]":"7.3","Cell RNA - HBF TERT88 [nTPM]":"9.3","Cell RNA - HDLM-2 [nTPM]":"10.9","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"12.4","Cell RNA - HeLa [nTPM]":"9.1","Cell RNA - Hep G2 [nTPM]":"13.9","Cell RNA - HHSteC [nTPM]":"33.6","Cell RNA - HL-60 [nTPM]":"4.9","Cell RNA - HMC-1 [nTPM]":"33.5","Cell RNA - HSkMC [nTPM]":"30.3","Cell RNA - hTCEpi [nTPM]":"24.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.6","Cell RNA - hTERT-HME1 [nTPM]":"20.8","Cell RNA - hTERT-RPE1 [nTPM]":"16.4","Cell RNA - HUVEC TERT2 [nTPM]":"14.8","Cell RNA - JURKAT [nTPM]":"9.2","Cell RNA - K-562 [nTPM]":"17.7","Cell RNA - Karpas-707 [nTPM]":"16.4","Cell RNA - LHCN-M2 [nTPM]":"17.6","Cell RNA - MCF7 [nTPM]":"17.5","Cell RNA - MOLT-4 [nTPM]":"8.3","Cell RNA - NB-4 [nTPM]":"8.4","Cell RNA - NTERA-2 [nTPM]":"11.2","Cell RNA - OE19 [nTPM]":"17.8","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"16.9","Cell RNA - RH-30 [nTPM]":"52.7","Cell RNA - RPMI-8226 [nTPM]":"7.3","Cell RNA - RPTEC TERT1 [nTPM]":"11.0","Cell RNA - RT4 [nTPM]":"14.1","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"8.8","Cell RNA - SiHa [nTPM]":"11.6","Cell RNA - SK-BR-3 [nTPM]":"7.5","Cell RNA - SK-MEL-30 [nTPM]":"19.3","Cell RNA - SuSa [nTPM]":"70.7","Cell RNA - T-47d [nTPM]":"11.1","Cell RNA - THP-1 [nTPM]":"8.8","Cell RNA - TIME [nTPM]":"15.7","Cell RNA - U-138 MG [nTPM]":"40.6","Cell RNA - U-2 OS [nTPM]":"16.6","Cell RNA - U-2197 [nTPM]":"56.5","Cell RNA - U-251 MG [nTPM]":"14.1","Cell RNA - U-266\/70 [nTPM]":"7.7","Cell RNA - U-266\/84 [nTPM]":"7.4","Cell RNA - U-698 [nTPM]":"5.7","Cell RNA - U-87 MG [nTPM]":"26.0","Cell RNA - U-937 [nTPM]":"10.8","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"3.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"6.0","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"19.0","Brain RNA - basal ganglia [nTPM]":"25.9","Brain RNA - cerebellum [nTPM]":"27.3","Brain RNA - cerebral cortex [nTPM]":"31.6","Brain RNA - hippocampal formation [nTPM]":"31.9","Brain RNA - hypothalamus [nTPM]":"14.0","Brain RNA - medulla oblongata [nTPM]":"21.3","Brain RNA - midbrain [nTPM]":"15.2","Brain RNA - pons [nTPM]":"22.0","Brain RNA - spinal cord [nTPM]":"14.0","Brain RNA - thalamus [nTPM]":"19.3","Brain RNA - white matter [nTPM]":"28.3","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"9.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"20.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"79.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - dendritic cells [nTPM]":"5.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.3","Single Cell Type RNA - Early spermatids [nTPM]":"14.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"12.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.7","Single Cell Type RNA - Erythroid cells [nTPM]":"81.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"20.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.8","Single Cell Type RNA - Hepatocytes [nTPM]":"24.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.6","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"21.6","Single Cell Type RNA - Langerhans cells [nTPM]":"19.2","Single Cell Type RNA - Late spermatids [nTPM]":"20.4","Single Cell Type RNA - Leydig cells [nTPM]":"28.0","Single Cell Type RNA - Macrophages [nTPM]":"13.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"12.2","Single Cell Type RNA - Muller glia cells [nTPM]":"13.3","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.8","Single Cell Type RNA - Paneth cells [nTPM]":"15.6","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"4.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.1","Single Cell Type RNA - Spermatocytes [nTPM]":"6.3","Single Cell Type RNA - Spermatogonia [nTPM]":"10.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.8","Single Cell Type RNA - T-cells [nTPM]":"10.0","Single Cell Type RNA - Theca cells [nTPM]":"16.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.6","Single Cell Type RNA - Urothelial cells [nTPM]":"13.0"},{"Gene":"MLH1","Gene synonym":["COCA2","FCC2","HNPCC","HNPCC2"],"Ensembl":"ENSG00000076242","Gene description":"MutL homolog 1","Uniprot":["P40692"],"Chromosome":"3","Position":"36993350-37050846","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary nonpolyposis colorectal cancer","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013294","HPA052707","HPA060714","CAB070868"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB013294":"AB_2533406","CAB070868":null,"HPA052707":"AB_2681923","HPA060714":"AB_2684348"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.24e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"17.9","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"17.4","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"22.1","Tissue RNA - breast [nTPM]":"15.4","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"9.1","Tissue RNA - cervix [nTPM]":"17.4","Tissue RNA - choroid plexus [nTPM]":"7.6","Tissue RNA - colon [nTPM]":"17.4","Tissue RNA - duodenum [nTPM]":"12.0","Tissue RNA - endometrium 1 [nTPM]":"16.3","Tissue RNA - epididymis [nTPM]":"14.0","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"11.1","Tissue RNA - heart muscle [nTPM]":"35.4","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"8.3","Tissue RNA - kidney [nTPM]":"16.0","Tissue RNA - liver [nTPM]":"19.1","Tissue RNA - lung [nTPM]":"15.8","Tissue RNA - lymph node [nTPM]":"21.9","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"15.1","Tissue RNA - pancreas [nTPM]":"16.6","Tissue RNA - parathyroid gland [nTPM]":"22.4","Tissue RNA - pituitary gland [nTPM]":"22.7","Tissue RNA - placenta [nTPM]":"14.8","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"14.5","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"12.1","Tissue RNA - seminal vesicle [nTPM]":"14.0","Tissue RNA - skeletal muscle [nTPM]":"49.1","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"19.2","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"18.8","Tissue RNA - stomach 1 [nTPM]":"15.5","Tissue RNA - testis [nTPM]":"25.4","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"28.4","Tissue RNA - thyroid gland [nTPM]":"19.2","Tissue RNA - tongue [nTPM]":"42.2","Tissue RNA - tonsil [nTPM]":"24.3","Tissue RNA - urinary bladder [nTPM]":"17.2","Tissue RNA - vagina [nTPM]":"14.0","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"37.1","Cell RNA - A549 [nTPM]":"56.7","Cell RNA - AF22 [nTPM]":"66.7","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"25.9","Cell RNA - ASC TERT1 [nTPM]":"34.5","Cell RNA - BEWO [nTPM]":"30.7","Cell RNA - BJ [nTPM]":"54.7","Cell RNA - BJ hTERT+ [nTPM]":"44.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.3","Cell RNA - CACO-2 [nTPM]":"43.4","Cell RNA - CAPAN-2 [nTPM]":"40.1","Cell RNA - Daudi [nTPM]":"92.2","Cell RNA - EFO-21 [nTPM]":"25.0","Cell RNA - fHDF\/TERT166 [nTPM]":"44.1","Cell RNA - GAMG [nTPM]":"33.6","Cell RNA - HaCaT [nTPM]":"24.7","Cell RNA - HAP1 [nTPM]":"65.2","Cell RNA - HBEC3-KT [nTPM]":"45.8","Cell RNA - HBF TERT88 [nTPM]":"68.5","Cell RNA - HDLM-2 [nTPM]":"42.2","Cell RNA - HEK 293 [nTPM]":"32.1","Cell RNA - HEL [nTPM]":"68.1","Cell RNA - HeLa [nTPM]":"42.3","Cell RNA - Hep G2 [nTPM]":"54.9","Cell RNA - HHSteC [nTPM]":"23.2","Cell RNA - HL-60 [nTPM]":"81.9","Cell RNA - HMC-1 [nTPM]":"40.5","Cell RNA - HSkMC [nTPM]":"28.4","Cell RNA - hTCEpi [nTPM]":"29.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"54.8","Cell RNA - hTERT-HME1 [nTPM]":"57.8","Cell RNA - hTERT-RPE1 [nTPM]":"21.9","Cell RNA - HUVEC TERT2 [nTPM]":"37.6","Cell RNA - JURKAT [nTPM]":"55.0","Cell RNA - K-562 [nTPM]":"86.0","Cell RNA - Karpas-707 [nTPM]":"32.0","Cell RNA - LHCN-M2 [nTPM]":"66.2","Cell RNA - MCF7 [nTPM]":"27.6","Cell RNA - MOLT-4 [nTPM]":"81.0","Cell RNA - NB-4 [nTPM]":"22.2","Cell RNA - NTERA-2 [nTPM]":"49.4","Cell RNA - OE19 [nTPM]":"38.4","Cell RNA - PC-3 [nTPM]":"31.6","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"90.6","Cell RNA - RPMI-8226 [nTPM]":"40.2","Cell RNA - RPTEC TERT1 [nTPM]":"35.1","Cell RNA - RT4 [nTPM]":"39.3","Cell RNA - SCLC-21H [nTPM]":"14.2","Cell RNA - SH-SY5Y [nTPM]":"36.1","Cell RNA - SiHa [nTPM]":"52.1","Cell RNA - SK-BR-3 [nTPM]":"56.9","Cell RNA - SK-MEL-30 [nTPM]":"32.7","Cell RNA - SuSa [nTPM]":"33.3","Cell RNA - T-47d [nTPM]":"79.9","Cell RNA - THP-1 [nTPM]":"55.6","Cell RNA - TIME [nTPM]":"28.8","Cell RNA - U-138 MG [nTPM]":"46.0","Cell RNA - U-2 OS [nTPM]":"50.5","Cell RNA - U-2197 [nTPM]":"44.0","Cell RNA - U-251 MG [nTPM]":"65.9","Cell RNA - U-266\/70 [nTPM]":"29.1","Cell RNA - U-266\/84 [nTPM]":"93.7","Cell RNA - U-698 [nTPM]":"88.1","Cell RNA - U-87 MG [nTPM]":"37.8","Cell RNA - U-937 [nTPM]":"71.9","Cell RNA - WM-115 [nTPM]":"45.7","Blood RNA - basophil [nTPM]":"12.6","Blood RNA - classical monocyte [nTPM]":"12.5","Blood RNA - eosinophil [nTPM]":"15.1","Blood RNA - gdT-cell [nTPM]":"12.7","Blood RNA - intermediate monocyte [nTPM]":"22.6","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"11.3","Blood RNA - memory CD4 T-cell [nTPM]":"7.7","Blood RNA - memory CD8 T-cell [nTPM]":"11.4","Blood RNA - myeloid DC [nTPM]":"14.3","Blood RNA - naive B-cell [nTPM]":"9.7","Blood RNA - naive CD4 T-cell [nTPM]":"8.4","Blood RNA - naive CD8 T-cell [nTPM]":"9.6","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"7.8","Blood RNA - non-classical monocyte [nTPM]":"29.2","Blood RNA - plasmacytoid DC [nTPM]":"5.9","Blood RNA - T-reg [nTPM]":"15.0","Blood RNA - total PBMC [nTPM]":"11.0","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"9.1","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"8.3","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"10.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.8","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"18.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"18.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"15.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.4","Single Cell Type RNA - dendritic cells [nTPM]":"16.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"14.6","Single Cell Type RNA - Early spermatids [nTPM]":"31.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"10.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"19.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.9","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.5","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"13.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"14.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"16.3","Single Cell Type RNA - Langerhans cells [nTPM]":"8.9","Single Cell Type RNA - Late spermatids [nTPM]":"13.2","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"18.2","Single Cell Type RNA - Muller glia cells [nTPM]":"15.9","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.3","Single Cell Type RNA - Paneth cells [nTPM]":"7.4","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"22.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.0","Single Cell Type RNA - Spermatocytes [nTPM]":"58.6","Single Cell Type RNA - Spermatogonia [nTPM]":"29.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"14.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.5"},{"Gene":"MLH3","Gene synonym":[],"Ensembl":"ENSG00000119684","Gene description":"MutL homolog 3","Uniprot":["Q9UHC1"],"Chromosome":"14","Position":"75013769-75051532","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary nonpolyposis colorectal cancer"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"106.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060570"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA060570":"AB_2684323"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"9.4","Tissue RNA - amygdala [nTPM]":"7.2","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"11.7","Tissue RNA - bone marrow [nTPM]":"2.3","Tissue RNA - breast [nTPM]":"7.9","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"8.6","Tissue RNA - cervix [nTPM]":"7.2","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"5.8","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"7.4","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"6.5","Tissue RNA - gallbladder [nTPM]":"6.1","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"6.3","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"7.3","Tissue RNA - lung [nTPM]":"5.2","Tissue RNA - lymph node [nTPM]":"6.6","Tissue RNA - medulla oblongata [nTPM]":"8.1","Tissue RNA - midbrain [nTPM]":"8.8","Tissue RNA - ovary [nTPM]":"8.1","Tissue RNA - pancreas [nTPM]":"5.3","Tissue RNA - parathyroid gland [nTPM]":"12.6","Tissue RNA - pituitary gland [nTPM]":"5.1","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"9.3","Tissue RNA - prostate [nTPM]":"7.6","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"5.4","Tissue RNA - seminal vesicle [nTPM]":"8.6","Tissue RNA - skeletal muscle [nTPM]":"6.6","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"4.8","Tissue RNA - smooth muscle [nTPM]":"5.5","Tissue RNA - spinal cord [nTPM]":"7.9","Tissue RNA - spleen [nTPM]":"6.4","Tissue RNA - stomach 1 [nTPM]":"4.5","Tissue RNA - testis [nTPM]":"6.7","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"11.1","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"5.3","Tissue RNA - vagina [nTPM]":"3.2","Tissue RNA - white matter [nTPM]":"19.8","Cell RNA - A-431 [nTPM]":"13.1","Cell RNA - A549 [nTPM]":"13.5","Cell RNA - AF22 [nTPM]":"10.3","Cell RNA - AN3-CA [nTPM]":"1.7","Cell RNA - ASC diff [nTPM]":"10.6","Cell RNA - ASC TERT1 [nTPM]":"17.0","Cell RNA - BEWO [nTPM]":"10.4","Cell RNA - BJ [nTPM]":"4.5","Cell RNA - BJ hTERT+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.3","Cell RNA - CACO-2 [nTPM]":"11.7","Cell RNA - CAPAN-2 [nTPM]":"16.5","Cell RNA - Daudi [nTPM]":"14.2","Cell RNA - EFO-21 [nTPM]":"3.7","Cell RNA - fHDF\/TERT166 [nTPM]":"5.5","Cell RNA - GAMG [nTPM]":"9.2","Cell RNA - HaCaT [nTPM]":"9.2","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"4.3","Cell RNA - HBF TERT88 [nTPM]":"10.4","Cell RNA - HDLM-2 [nTPM]":"14.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"9.3","Cell RNA - HeLa [nTPM]":"8.7","Cell RNA - Hep G2 [nTPM]":"7.1","Cell RNA - HHSteC [nTPM]":"8.6","Cell RNA - HL-60 [nTPM]":"4.0","Cell RNA - HMC-1 [nTPM]":"6.3","Cell RNA - HSkMC [nTPM]":"6.3","Cell RNA - hTCEpi [nTPM]":"10.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.2","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"8.7","Cell RNA - HUVEC TERT2 [nTPM]":"12.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"8.8","Cell RNA - Karpas-707 [nTPM]":"11.4","Cell RNA - LHCN-M2 [nTPM]":"15.8","Cell RNA - MCF7 [nTPM]":"11.3","Cell RNA - MOLT-4 [nTPM]":"6.3","Cell RNA - NB-4 [nTPM]":"4.5","Cell RNA - NTERA-2 [nTPM]":"8.7","Cell RNA - OE19 [nTPM]":"10.6","Cell RNA - PC-3 [nTPM]":"7.6","Cell RNA - REH [nTPM]":"11.3","Cell RNA - RH-30 [nTPM]":"6.3","Cell RNA - RPMI-8226 [nTPM]":"3.1","Cell RNA - RPTEC TERT1 [nTPM]":"17.4","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"14.9","Cell RNA - SH-SY5Y [nTPM]":"10.5","Cell RNA - SiHa [nTPM]":"14.4","Cell RNA - SK-BR-3 [nTPM]":"9.9","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"10.3","Cell RNA - T-47d [nTPM]":"13.1","Cell RNA - THP-1 [nTPM]":"9.0","Cell RNA - TIME [nTPM]":"6.1","Cell RNA - U-138 MG [nTPM]":"2.9","Cell RNA - U-2 OS [nTPM]":"5.9","Cell RNA - U-2197 [nTPM]":"4.3","Cell RNA - U-251 MG [nTPM]":"4.5","Cell RNA - U-266\/70 [nTPM]":"14.4","Cell RNA - U-266\/84 [nTPM]":"15.0","Cell RNA - U-698 [nTPM]":"15.4","Cell RNA - U-87 MG [nTPM]":"10.7","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"13.2","Blood RNA - basophil [nTPM]":"5.1","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"1.7","Blood RNA - gdT-cell [nTPM]":"4.6","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"3.5","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.2","Blood RNA - myeloid DC [nTPM]":"2.9","Blood RNA - naive B-cell [nTPM]":"5.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.3","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"6.3","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"2.4","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"5.9","Brain RNA - amygdala [nTPM]":"7.2","Brain RNA - basal ganglia [nTPM]":"11.7","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"8.6","Brain RNA - hippocampal formation [nTPM]":"6.3","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"8.1","Brain RNA - midbrain [nTPM]":"8.8","Brain RNA - pons [nTPM]":"9.3","Brain RNA - spinal cord [nTPM]":"7.9","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"19.8","Single Cell Type RNA - Adipocytes [nTPM]":"19.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.3","Single Cell Type RNA - Astrocytes [nTPM]":"47.3","Single Cell Type RNA - B-cells [nTPM]":"16.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"49.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"15.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.2","Single Cell Type RNA - dendritic cells [nTPM]":"15.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.4","Single Cell Type RNA - Early spermatids [nTPM]":"6.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.3","Single Cell Type RNA - Endothelial cells [nTPM]":"18.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"6.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.8","Single Cell Type RNA - Fibroblasts [nTPM]":"25.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.8","Single Cell Type RNA - granulocytes [nTPM]":"23.5","Single Cell Type RNA - Granulosa cells [nTPM]":"40.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"15.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.3","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"52.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.4","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.1","Single Cell Type RNA - Langerhans cells [nTPM]":"6.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"39.7","Single Cell Type RNA - Macrophages [nTPM]":"47.7","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"14.6","Single Cell Type RNA - Muller glia cells [nTPM]":"28.5","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"51.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"106.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.3","Single Cell Type RNA - Paneth cells [nTPM]":"12.0","Single Cell Type RNA - Peritubular cells [nTPM]":"51.1","Single Cell Type RNA - Plasma cells [nTPM]":"8.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.3","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.3","Single Cell Type RNA - Spermatocytes [nTPM]":"54.4","Single Cell Type RNA - Spermatogonia [nTPM]":"10.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.1","Single Cell Type RNA - T-cells [nTPM]":"13.6","Single Cell Type RNA - Theca cells [nTPM]":"31.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.9","Single Cell Type RNA - Urothelial cells [nTPM]":"12.2"},{"Gene":"MSH2","Gene synonym":["COCA1","HNPCC","HNPCC1"],"Ensembl":"ENSG00000095002","Gene description":"MutS homolog 2","Uniprot":["P43246"],"Chromosome":"2","Position":"47403067-47663146","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary nonpolyposis colorectal cancer","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"46.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009572","HPA066845","CAB070867"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB009572":"AB_2144828","CAB070867":null,"HPA066845":"AB_2732752"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.44e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.1","Tissue RNA - adrenal gland [nTPM]":"7.5","Tissue RNA - amygdala [nTPM]":"8.3","Tissue RNA - appendix [nTPM]":"12.8","Tissue RNA - basal ganglia [nTPM]":"10.5","Tissue RNA - bone marrow [nTPM]":"15.7","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"14.6","Tissue RNA - cerebral cortex [nTPM]":"10.6","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"11.9","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"11.7","Tissue RNA - epididymis [nTPM]":"14.0","Tissue RNA - esophagus [nTPM]":"9.5","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"9.6","Tissue RNA - hypothalamus [nTPM]":"9.0","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"6.7","Tissue RNA - lung [nTPM]":"8.1","Tissue RNA - lymph node [nTPM]":"23.7","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"8.0","Tissue RNA - ovary [nTPM]":"8.7","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"14.8","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"11.6","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"8.6","Tissue RNA - rectum [nTPM]":"15.0","Tissue RNA - retina [nTPM]":"34.9","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"11.1","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"8.8","Tissue RNA - spinal cord [nTPM]":"8.5","Tissue RNA - spleen [nTPM]":"10.8","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"16.2","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"32.6","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"25.0","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"8.9","Cell RNA - A-431 [nTPM]":"114.3","Cell RNA - A549 [nTPM]":"35.3","Cell RNA - AF22 [nTPM]":"103.3","Cell RNA - AN3-CA [nTPM]":"57.9","Cell RNA - ASC diff [nTPM]":"7.3","Cell RNA - ASC TERT1 [nTPM]":"21.2","Cell RNA - BEWO [nTPM]":"64.3","Cell RNA - BJ [nTPM]":"62.9","Cell RNA - BJ hTERT+ [nTPM]":"33.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"80.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"76.9","Cell RNA - CACO-2 [nTPM]":"72.3","Cell RNA - CAPAN-2 [nTPM]":"50.1","Cell RNA - Daudi [nTPM]":"141.2","Cell RNA - EFO-21 [nTPM]":"84.6","Cell RNA - fHDF\/TERT166 [nTPM]":"23.8","Cell RNA - GAMG [nTPM]":"56.6","Cell RNA - HaCaT [nTPM]":"49.8","Cell RNA - HAP1 [nTPM]":"78.6","Cell RNA - HBEC3-KT [nTPM]":"37.4","Cell RNA - HBF TERT88 [nTPM]":"122.3","Cell RNA - HDLM-2 [nTPM]":"68.1","Cell RNA - HEK 293 [nTPM]":"55.8","Cell RNA - HEL [nTPM]":"99.3","Cell RNA - HeLa [nTPM]":"42.3","Cell RNA - Hep G2 [nTPM]":"65.6","Cell RNA - HHSteC [nTPM]":"7.7","Cell RNA - HL-60 [nTPM]":"97.7","Cell RNA - HMC-1 [nTPM]":"34.9","Cell RNA - HSkMC [nTPM]":"12.3","Cell RNA - hTCEpi [nTPM]":"11.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.1","Cell RNA - hTERT-HME1 [nTPM]":"19.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.1","Cell RNA - HUVEC TERT2 [nTPM]":"45.2","Cell RNA - JURKAT [nTPM]":"3.9","Cell RNA - K-562 [nTPM]":"165.1","Cell RNA - Karpas-707 [nTPM]":"34.0","Cell RNA - LHCN-M2 [nTPM]":"63.1","Cell RNA - MCF7 [nTPM]":"44.2","Cell RNA - MOLT-4 [nTPM]":"119.6","Cell RNA - NB-4 [nTPM]":"75.4","Cell RNA - NTERA-2 [nTPM]":"195.7","Cell RNA - OE19 [nTPM]":"69.3","Cell RNA - PC-3 [nTPM]":"45.1","Cell RNA - REH [nTPM]":"151.1","Cell RNA - RH-30 [nTPM]":"182.2","Cell RNA - RPMI-8226 [nTPM]":"84.4","Cell RNA - RPTEC TERT1 [nTPM]":"35.8","Cell RNA - RT4 [nTPM]":"57.3","Cell RNA - SCLC-21H [nTPM]":"85.9","Cell RNA - SH-SY5Y [nTPM]":"91.6","Cell RNA - SiHa [nTPM]":"58.4","Cell RNA - SK-BR-3 [nTPM]":"49.2","Cell RNA - SK-MEL-30 [nTPM]":"48.0","Cell RNA - SuSa [nTPM]":"83.6","Cell RNA - T-47d [nTPM]":"46.9","Cell RNA - THP-1 [nTPM]":"38.8","Cell RNA - TIME [nTPM]":"18.7","Cell RNA - U-138 MG [nTPM]":"55.5","Cell RNA - U-2 OS [nTPM]":"70.9","Cell RNA - U-2197 [nTPM]":"57.1","Cell RNA - U-251 MG [nTPM]":"74.6","Cell RNA - U-266\/70 [nTPM]":"20.8","Cell RNA - U-266\/84 [nTPM]":"63.4","Cell RNA - U-698 [nTPM]":"180.1","Cell RNA - U-87 MG [nTPM]":"33.1","Cell RNA - U-937 [nTPM]":"72.5","Cell RNA - WM-115 [nTPM]":"35.4","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"8.0","Blood RNA - intermediate monocyte [nTPM]":"4.4","Blood RNA - MAIT T-cell [nTPM]":"9.3","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"7.7","Blood RNA - memory CD8 T-cell [nTPM]":"10.3","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"7.9","Blood RNA - naive CD4 T-cell [nTPM]":"12.6","Blood RNA - naive CD8 T-cell [nTPM]":"13.1","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"14.2","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"11.8","Blood RNA - total PBMC [nTPM]":"6.5","Brain RNA - amygdala [nTPM]":"8.3","Brain RNA - basal ganglia [nTPM]":"10.5","Brain RNA - cerebellum [nTPM]":"14.6","Brain RNA - cerebral cortex [nTPM]":"10.6","Brain RNA - hippocampal formation [nTPM]":"9.6","Brain RNA - hypothalamus [nTPM]":"9.0","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"8.0","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"8.5","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"8.9","Single Cell Type RNA - Adipocytes [nTPM]":"14.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"13.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"17.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.9","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.5","Single Cell Type RNA - Early spermatids [nTPM]":"17.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"13.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"54.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"59.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.8","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"28.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"58.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.1","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"22.8","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"5.5","Single Cell Type RNA - Muller glia cells [nTPM]":"22.6","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"54.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.3","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"56.5","Single Cell Type RNA - Spermatogonia [nTPM]":"50.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"24.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.5","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"MSH6","Gene synonym":["GTBP"],"Ensembl":"ENSG00000116062","Gene description":"MutS homolog 6","Uniprot":["P52701"],"Chromosome":"2","Position":"47695530-47810063","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Host-virus interaction"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary nonpolyposis colorectal cancer"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"119.6","Theca cells":"114.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"31.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009091","HPA028376","HPA028446","CAB070870"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"CAB009091":"AB_670083","CAB070870":"AB_2144959","HPA028376":"AB_10598909","HPA028446":"AB_10602182"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.7","Tissue RNA - adrenal gland [nTPM]":"22.7","Tissue RNA - amygdala [nTPM]":"9.3","Tissue RNA - appendix [nTPM]":"17.7","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"24.0","Tissue RNA - breast [nTPM]":"16.2","Tissue RNA - cerebellum [nTPM]":"15.0","Tissue RNA - cerebral cortex [nTPM]":"12.7","Tissue RNA - cervix [nTPM]":"15.5","Tissue RNA - choroid plexus [nTPM]":"12.7","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"9.0","Tissue RNA - endometrium 1 [nTPM]":"27.7","Tissue RNA - epididymis [nTPM]":"10.2","Tissue RNA - esophagus [nTPM]":"11.7","Tissue RNA - fallopian tube [nTPM]":"17.8","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"9.3","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"12.1","Tissue RNA - liver [nTPM]":"19.8","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"28.4","Tissue RNA - medulla oblongata [nTPM]":"12.7","Tissue RNA - midbrain [nTPM]":"11.7","Tissue RNA - ovary [nTPM]":"53.0","Tissue RNA - pancreas [nTPM]":"31.3","Tissue RNA - parathyroid gland [nTPM]":"17.0","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"20.3","Tissue RNA - pons [nTPM]":"13.0","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"12.4","Tissue RNA - retina [nTPM]":"21.6","Tissue RNA - salivary gland [nTPM]":"10.8","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"10.5","Tissue RNA - skin 1 [nTPM]":"13.1","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"27.2","Tissue RNA - spinal cord [nTPM]":"10.7","Tissue RNA - spleen [nTPM]":"12.7","Tissue RNA - stomach 1 [nTPM]":"10.9","Tissue RNA - testis [nTPM]":"35.3","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"36.3","Tissue RNA - thyroid gland [nTPM]":"17.2","Tissue RNA - tongue [nTPM]":"11.2","Tissue RNA - tonsil [nTPM]":"31.0","Tissue RNA - urinary bladder [nTPM]":"12.8","Tissue RNA - vagina [nTPM]":"12.2","Tissue RNA - white matter [nTPM]":"19.9","Cell RNA - A-431 [nTPM]":"116.5","Cell RNA - A549 [nTPM]":"77.6","Cell RNA - AF22 [nTPM]":"128.4","Cell RNA - AN3-CA [nTPM]":"37.5","Cell RNA - ASC diff [nTPM]":"42.3","Cell RNA - ASC TERT1 [nTPM]":"46.3","Cell RNA - BEWO [nTPM]":"67.9","Cell RNA - BJ [nTPM]":"63.6","Cell RNA - BJ hTERT+ [nTPM]":"51.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"60.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.8","Cell RNA - CACO-2 [nTPM]":"67.2","Cell RNA - CAPAN-2 [nTPM]":"41.4","Cell RNA - Daudi [nTPM]":"158.1","Cell RNA - EFO-21 [nTPM]":"84.5","Cell RNA - fHDF\/TERT166 [nTPM]":"59.5","Cell RNA - GAMG [nTPM]":"82.0","Cell RNA - HaCaT [nTPM]":"46.0","Cell RNA - HAP1 [nTPM]":"130.3","Cell RNA - HBEC3-KT [nTPM]":"74.3","Cell RNA - HBF TERT88 [nTPM]":"82.1","Cell RNA - HDLM-2 [nTPM]":"80.7","Cell RNA - HEK 293 [nTPM]":"69.0","Cell RNA - HEL [nTPM]":"117.0","Cell RNA - HeLa [nTPM]":"60.8","Cell RNA - Hep G2 [nTPM]":"71.1","Cell RNA - HHSteC [nTPM]":"28.8","Cell RNA - HL-60 [nTPM]":"131.5","Cell RNA - HMC-1 [nTPM]":"37.8","Cell RNA - HSkMC [nTPM]":"38.6","Cell RNA - hTCEpi [nTPM]":"28.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"60.7","Cell RNA - hTERT-HME1 [nTPM]":"41.6","Cell RNA - hTERT-RPE1 [nTPM]":"53.8","Cell RNA - HUVEC TERT2 [nTPM]":"40.8","Cell RNA - JURKAT [nTPM]":"5.3","Cell RNA - K-562 [nTPM]":"115.9","Cell RNA - Karpas-707 [nTPM]":"69.8","Cell RNA - LHCN-M2 [nTPM]":"61.8","Cell RNA - MCF7 [nTPM]":"85.5","Cell RNA - MOLT-4 [nTPM]":"144.2","Cell RNA - NB-4 [nTPM]":"80.1","Cell RNA - NTERA-2 [nTPM]":"130.7","Cell RNA - OE19 [nTPM]":"81.3","Cell RNA - PC-3 [nTPM]":"37.7","Cell RNA - REH [nTPM]":"219.6","Cell RNA - RH-30 [nTPM]":"204.3","Cell RNA - RPMI-8226 [nTPM]":"84.7","Cell RNA - RPTEC TERT1 [nTPM]":"44.5","Cell RNA - RT4 [nTPM]":"76.2","Cell RNA - SCLC-21H [nTPM]":"92.8","Cell RNA - SH-SY5Y [nTPM]":"100.3","Cell RNA - SiHa [nTPM]":"79.1","Cell RNA - SK-BR-3 [nTPM]":"40.4","Cell RNA - SK-MEL-30 [nTPM]":"42.7","Cell RNA - SuSa [nTPM]":"124.3","Cell RNA - T-47d [nTPM]":"54.6","Cell RNA - THP-1 [nTPM]":"42.6","Cell RNA - TIME [nTPM]":"33.4","Cell RNA - U-138 MG [nTPM]":"72.2","Cell RNA - U-2 OS [nTPM]":"92.3","Cell RNA - U-2197 [nTPM]":"54.6","Cell RNA - U-251 MG [nTPM]":"80.6","Cell RNA - U-266\/70 [nTPM]":"63.8","Cell RNA - U-266\/84 [nTPM]":"79.3","Cell RNA - U-698 [nTPM]":"276.2","Cell RNA - U-87 MG [nTPM]":"61.9","Cell RNA - U-937 [nTPM]":"77.9","Cell RNA - WM-115 [nTPM]":"42.4","Blood RNA - basophil [nTPM]":"7.7","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"4.8","Blood RNA - intermediate monocyte [nTPM]":"6.2","Blood RNA - MAIT T-cell [nTPM]":"5.5","Blood RNA - memory B-cell [nTPM]":"4.3","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"5.5","Blood RNA - naive B-cell [nTPM]":"4.2","Blood RNA - naive CD4 T-cell [nTPM]":"8.4","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"6.4","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"5.3","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"9.3","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"15.0","Brain RNA - cerebral cortex [nTPM]":"12.7","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"12.7","Brain RNA - midbrain [nTPM]":"11.7","Brain RNA - pons [nTPM]":"13.0","Brain RNA - spinal cord [nTPM]":"10.7","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"19.9","Single Cell Type RNA - Adipocytes [nTPM]":"19.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"19.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"25.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"21.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.6","Single Cell Type RNA - dendritic cells [nTPM]":"20.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.7","Single Cell Type RNA - Early spermatids [nTPM]":"46.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"47.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.8","Single Cell Type RNA - Fibroblasts [nTPM]":"24.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.7","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"119.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"10.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.0","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"5.6","Single Cell Type RNA - Langerhans cells [nTPM]":"13.2","Single Cell Type RNA - Late spermatids [nTPM]":"17.5","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"16.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"10.0","Single Cell Type RNA - Muller glia cells [nTPM]":"22.7","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.7","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"31.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.0","Single Cell Type RNA - Spermatocytes [nTPM]":"54.3","Single Cell Type RNA - Spermatogonia [nTPM]":"48.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.6","Single Cell Type RNA - T-cells [nTPM]":"19.8","Single Cell Type RNA - Theca cells [nTPM]":"114.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.1","Single Cell Type RNA - Urothelial cells [nTPM]":"11.7"},{"Gene":"PMS2","Gene synonym":["H_DJ0042M02.9","HNPCC4","MLH4","PMSL2"],"Ensembl":"ENSG00000122512","Gene description":"PMS1 homolog 2, mismatch repair system component","Uniprot":["P54278"],"Chromosome":"7","Position":"5970925-6009106","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Endonuclease","Hydrolase","Nuclease"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary nonpolyposis colorectal cancer","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010235","HPA066490","HPA070310"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB010235":"AB_2167281","HPA066490":"AB_2685677","HPA070310":"AB_2686250"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.23e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.3","Tissue RNA - adrenal gland [nTPM]":"5.1","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"5.3","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"6.3","Tissue RNA - cerebral cortex [nTPM]":"7.6","Tissue RNA - cervix [nTPM]":"4.8","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"4.8","Tissue RNA - duodenum [nTPM]":"5.7","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"5.7","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"4.1","Tissue RNA - hippocampal formation [nTPM]":"7.4","Tissue RNA - hypothalamus [nTPM]":"5.8","Tissue RNA - kidney [nTPM]":"10.4","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"4.4","Tissue RNA - lymph node [nTPM]":"8.4","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"11.0","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"4.8","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"5.2","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"8.4","Tissue RNA - salivary gland [nTPM]":"5.7","Tissue RNA - seminal vesicle [nTPM]":"5.5","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"11.9","Tissue RNA - small intestine [nTPM]":"5.3","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"5.9","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"8.8","Tissue RNA - thyroid gland [nTPM]":"9.2","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"5.1","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"7.0","Cell RNA - A-431 [nTPM]":"15.1","Cell RNA - A549 [nTPM]":"16.7","Cell RNA - AF22 [nTPM]":"12.9","Cell RNA - AN3-CA [nTPM]":"32.2","Cell RNA - ASC diff [nTPM]":"9.0","Cell RNA - ASC TERT1 [nTPM]":"13.6","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"7.8","Cell RNA - BJ hTERT+ [nTPM]":"5.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.6","Cell RNA - CACO-2 [nTPM]":"14.0","Cell RNA - CAPAN-2 [nTPM]":"9.9","Cell RNA - Daudi [nTPM]":"28.2","Cell RNA - EFO-21 [nTPM]":"8.7","Cell RNA - fHDF\/TERT166 [nTPM]":"10.9","Cell RNA - GAMG [nTPM]":"17.2","Cell RNA - HaCaT [nTPM]":"19.6","Cell RNA - HAP1 [nTPM]":"19.2","Cell RNA - HBEC3-KT [nTPM]":"6.6","Cell RNA - HBF TERT88 [nTPM]":"8.0","Cell RNA - HDLM-2 [nTPM]":"11.3","Cell RNA - HEK 293 [nTPM]":"7.2","Cell RNA - HEL [nTPM]":"12.0","Cell RNA - HeLa [nTPM]":"12.5","Cell RNA - Hep G2 [nTPM]":"10.1","Cell RNA - HHSteC [nTPM]":"15.9","Cell RNA - HL-60 [nTPM]":"15.8","Cell RNA - HMC-1 [nTPM]":"9.4","Cell RNA - HSkMC [nTPM]":"15.1","Cell RNA - hTCEpi [nTPM]":"14.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.4","Cell RNA - hTERT-HME1 [nTPM]":"22.3","Cell RNA - hTERT-RPE1 [nTPM]":"11.4","Cell RNA - HUVEC TERT2 [nTPM]":"13.7","Cell RNA - JURKAT [nTPM]":"15.2","Cell RNA - K-562 [nTPM]":"22.9","Cell RNA - Karpas-707 [nTPM]":"12.6","Cell RNA - LHCN-M2 [nTPM]":"11.9","Cell RNA - MCF7 [nTPM]":"15.5","Cell RNA - MOLT-4 [nTPM]":"5.2","Cell RNA - NB-4 [nTPM]":"17.1","Cell RNA - NTERA-2 [nTPM]":"13.3","Cell RNA - OE19 [nTPM]":"7.6","Cell RNA - PC-3 [nTPM]":"9.6","Cell RNA - REH [nTPM]":"16.3","Cell RNA - RH-30 [nTPM]":"15.3","Cell RNA - RPMI-8226 [nTPM]":"14.0","Cell RNA - RPTEC TERT1 [nTPM]":"16.4","Cell RNA - RT4 [nTPM]":"11.0","Cell RNA - SCLC-21H [nTPM]":"11.9","Cell RNA - SH-SY5Y [nTPM]":"25.7","Cell RNA - SiHa [nTPM]":"13.3","Cell RNA - SK-BR-3 [nTPM]":"23.0","Cell RNA - SK-MEL-30 [nTPM]":"16.2","Cell RNA - SuSa [nTPM]":"18.0","Cell RNA - T-47d [nTPM]":"27.1","Cell RNA - THP-1 [nTPM]":"11.8","Cell RNA - TIME [nTPM]":"12.4","Cell RNA - U-138 MG [nTPM]":"9.3","Cell RNA - U-2 OS [nTPM]":"21.2","Cell RNA - U-2197 [nTPM]":"14.2","Cell RNA - U-251 MG [nTPM]":"14.6","Cell RNA - U-266\/70 [nTPM]":"19.8","Cell RNA - U-266\/84 [nTPM]":"32.8","Cell RNA - U-698 [nTPM]":"27.5","Cell RNA - U-87 MG [nTPM]":"7.2","Cell RNA - U-937 [nTPM]":"15.3","Cell RNA - WM-115 [nTPM]":"22.9","Blood RNA - basophil [nTPM]":"5.0","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"4.1","Blood RNA - MAIT T-cell [nTPM]":"4.9","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"3.8","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"3.4","Blood RNA - naive CD4 T-cell [nTPM]":"4.4","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"2.3","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"3.4","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"6.3","Brain RNA - cerebral cortex [nTPM]":"7.6","Brain RNA - hippocampal formation [nTPM]":"7.4","Brain RNA - hypothalamus [nTPM]":"5.8","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"7.0","Single Cell Type RNA - Adipocytes [nTPM]":"12.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"13.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"13.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"9.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - dendritic cells [nTPM]":"15.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"9.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.6","Single Cell Type RNA - Endothelial cells [nTPM]":"10.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.8","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"11.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.1","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"6.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"8.7","Single Cell Type RNA - Muller glia cells [nTPM]":"7.8","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"9.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.0","Single Cell Type RNA - Spermatocytes [nTPM]":"34.5","Single Cell Type RNA - Spermatogonia [nTPM]":"11.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - T-cells [nTPM]":"11.4","Single Cell Type RNA - Theca cells [nTPM]":"11.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.6","Single Cell Type RNA - Urothelial cells [nTPM]":"11.1"},{"Gene":"PRKAR1A","Gene synonym":["CNC1","PRKAR1","TSE1"],"Ensembl":"ENSG00000108946","Gene description":"Protein kinase cAMP-dependent type I regulatory subunit alpha","Uniprot":["P10644"],"Chromosome":"17","Position":"68511780-68551319","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Cushing syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"606.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019378","HPA049979"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB019378":null,"HPA049979":"AB_2680980"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"125.9","Tissue RNA - adrenal gland [nTPM]":"158.2","Tissue RNA - amygdala [nTPM]":"72.0","Tissue RNA - appendix [nTPM]":"124.1","Tissue RNA - basal ganglia [nTPM]":"83.2","Tissue RNA - bone marrow [nTPM]":"57.1","Tissue RNA - breast [nTPM]":"118.4","Tissue RNA - cerebellum [nTPM]":"76.7","Tissue RNA - cerebral cortex [nTPM]":"119.1","Tissue RNA - cervix [nTPM]":"151.2","Tissue RNA - choroid plexus [nTPM]":"97.3","Tissue RNA - colon [nTPM]":"70.0","Tissue RNA - duodenum [nTPM]":"51.7","Tissue RNA - endometrium 1 [nTPM]":"145.5","Tissue RNA - epididymis [nTPM]":"122.3","Tissue RNA - esophagus [nTPM]":"98.5","Tissue RNA - fallopian tube [nTPM]":"141.3","Tissue RNA - gallbladder [nTPM]":"125.2","Tissue RNA - heart muscle [nTPM]":"430.0","Tissue RNA - hippocampal formation [nTPM]":"89.0","Tissue RNA - hypothalamus [nTPM]":"102.1","Tissue RNA - kidney [nTPM]":"164.3","Tissue RNA - liver [nTPM]":"150.8","Tissue RNA - lung [nTPM]":"163.7","Tissue RNA - lymph node [nTPM]":"111.4","Tissue RNA - medulla oblongata [nTPM]":"85.6","Tissue RNA - midbrain [nTPM]":"91.8","Tissue RNA - ovary [nTPM]":"202.8","Tissue RNA - pancreas [nTPM]":"63.1","Tissue RNA - parathyroid gland [nTPM]":"300.2","Tissue RNA - pituitary gland [nTPM]":"88.0","Tissue RNA - placenta [nTPM]":"164.3","Tissue RNA - pons [nTPM]":"105.0","Tissue RNA - prostate [nTPM]":"114.5","Tissue RNA - rectum [nTPM]":"79.1","Tissue RNA - retina [nTPM]":"132.2","Tissue RNA - salivary gland [nTPM]":"169.7","Tissue RNA - seminal vesicle [nTPM]":"137.6","Tissue RNA - skeletal muscle [nTPM]":"250.6","Tissue RNA - skin 1 [nTPM]":"63.8","Tissue RNA - small intestine [nTPM]":"58.7","Tissue RNA - smooth muscle [nTPM]":"132.1","Tissue RNA - spinal cord [nTPM]":"71.7","Tissue RNA - spleen [nTPM]":"121.7","Tissue RNA - stomach 1 [nTPM]":"86.9","Tissue RNA - testis [nTPM]":"130.8","Tissue RNA - thalamus [nTPM]":"91.8","Tissue RNA - thymus [nTPM]":"109.4","Tissue RNA - thyroid gland [nTPM]":"173.6","Tissue RNA - tongue [nTPM]":"147.4","Tissue RNA - tonsil [nTPM]":"103.6","Tissue RNA - urinary bladder [nTPM]":"136.4","Tissue RNA - vagina [nTPM]":"67.6","Tissue RNA - white matter [nTPM]":"93.5","Cell RNA - A-431 [nTPM]":"95.5","Cell RNA - A549 [nTPM]":"180.0","Cell RNA - AF22 [nTPM]":"225.9","Cell RNA - AN3-CA [nTPM]":"136.1","Cell RNA - ASC diff [nTPM]":"294.6","Cell RNA - ASC TERT1 [nTPM]":"331.7","Cell RNA - BEWO [nTPM]":"33.9","Cell RNA - BJ [nTPM]":"125.7","Cell RNA - BJ hTERT+ [nTPM]":"257.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"192.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"168.6","Cell RNA - CACO-2 [nTPM]":"70.5","Cell RNA - CAPAN-2 [nTPM]":"125.5","Cell RNA - Daudi [nTPM]":"96.3","Cell RNA - EFO-21 [nTPM]":"84.3","Cell RNA - fHDF\/TERT166 [nTPM]":"276.7","Cell RNA - GAMG [nTPM]":"196.8","Cell RNA - HaCaT [nTPM]":"77.2","Cell RNA - HAP1 [nTPM]":"168.8","Cell RNA - HBEC3-KT [nTPM]":"204.2","Cell RNA - HBF TERT88 [nTPM]":"273.8","Cell RNA - HDLM-2 [nTPM]":"65.8","Cell RNA - HEK 293 [nTPM]":"60.4","Cell RNA - HEL [nTPM]":"149.1","Cell RNA - HeLa [nTPM]":"154.0","Cell RNA - Hep G2 [nTPM]":"233.0","Cell RNA - HHSteC [nTPM]":"213.0","Cell RNA - HL-60 [nTPM]":"115.8","Cell RNA - HMC-1 [nTPM]":"160.2","Cell RNA - HSkMC [nTPM]":"239.1","Cell RNA - hTCEpi [nTPM]":"207.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"222.3","Cell RNA - hTERT-HME1 [nTPM]":"185.9","Cell RNA - hTERT-RPE1 [nTPM]":"215.0","Cell RNA - HUVEC TERT2 [nTPM]":"324.6","Cell RNA - JURKAT [nTPM]":"80.8","Cell RNA - K-562 [nTPM]":"68.5","Cell RNA - Karpas-707 [nTPM]":"147.2","Cell RNA - LHCN-M2 [nTPM]":"236.4","Cell RNA - MCF7 [nTPM]":"181.0","Cell RNA - MOLT-4 [nTPM]":"128.2","Cell RNA - NB-4 [nTPM]":"60.9","Cell RNA - NTERA-2 [nTPM]":"83.9","Cell RNA - OE19 [nTPM]":"97.7","Cell RNA - PC-3 [nTPM]":"121.4","Cell RNA - REH [nTPM]":"88.1","Cell RNA - RH-30 [nTPM]":"373.6","Cell RNA - RPMI-8226 [nTPM]":"106.7","Cell RNA - RPTEC TERT1 [nTPM]":"292.4","Cell RNA - RT4 [nTPM]":"204.3","Cell RNA - SCLC-21H [nTPM]":"81.8","Cell RNA - SH-SY5Y [nTPM]":"110.3","Cell RNA - SiHa [nTPM]":"115.4","Cell RNA - SK-BR-3 [nTPM]":"207.6","Cell RNA - SK-MEL-30 [nTPM]":"496.8","Cell RNA - SuSa [nTPM]":"208.5","Cell RNA - T-47d [nTPM]":"162.8","Cell RNA - THP-1 [nTPM]":"161.1","Cell RNA - TIME [nTPM]":"232.2","Cell RNA - U-138 MG [nTPM]":"269.4","Cell RNA - U-2 OS [nTPM]":"127.6","Cell RNA - U-2197 [nTPM]":"123.3","Cell RNA - U-251 MG [nTPM]":"119.0","Cell RNA - U-266\/70 [nTPM]":"121.6","Cell RNA - U-266\/84 [nTPM]":"93.5","Cell RNA - U-698 [nTPM]":"142.4","Cell RNA - U-87 MG [nTPM]":"163.0","Cell RNA - U-937 [nTPM]":"107.8","Cell RNA - WM-115 [nTPM]":"171.8","Blood RNA - basophil [nTPM]":"149.6","Blood RNA - classical monocyte [nTPM]":"108.3","Blood RNA - eosinophil [nTPM]":"189.4","Blood RNA - gdT-cell [nTPM]":"48.6","Blood RNA - intermediate monocyte [nTPM]":"101.0","Blood RNA - MAIT T-cell [nTPM]":"48.8","Blood RNA - memory B-cell [nTPM]":"42.8","Blood RNA - memory CD4 T-cell [nTPM]":"35.9","Blood RNA - memory CD8 T-cell [nTPM]":"43.6","Blood RNA - myeloid DC [nTPM]":"105.9","Blood RNA - naive B-cell [nTPM]":"32.3","Blood RNA - naive CD4 T-cell [nTPM]":"32.1","Blood RNA - naive CD8 T-cell [nTPM]":"35.9","Blood RNA - neutrophil [nTPM]":"208.2","Blood RNA - NK-cell [nTPM]":"76.1","Blood RNA - non-classical monocyte [nTPM]":"120.9","Blood RNA - plasmacytoid DC [nTPM]":"34.7","Blood RNA - T-reg [nTPM]":"50.9","Blood RNA - total PBMC [nTPM]":"113.5","Brain RNA - amygdala [nTPM]":"72.0","Brain RNA - basal ganglia [nTPM]":"83.2","Brain RNA - cerebellum [nTPM]":"76.7","Brain RNA - cerebral cortex [nTPM]":"119.1","Brain RNA - hippocampal formation [nTPM]":"89.0","Brain RNA - hypothalamus [nTPM]":"102.1","Brain RNA - medulla oblongata [nTPM]":"85.6","Brain RNA - midbrain [nTPM]":"91.8","Brain RNA - pons [nTPM]":"105.0","Brain RNA - spinal cord [nTPM]":"71.7","Brain RNA - thalamus [nTPM]":"91.8","Brain RNA - white matter [nTPM]":"93.5","Single Cell Type RNA - Adipocytes [nTPM]":"134.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"147.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"263.4","Single Cell Type RNA - Astrocytes [nTPM]":"38.5","Single Cell Type RNA - B-cells [nTPM]":"126.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"142.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"100.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"136.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"116.7","Single Cell Type RNA - Bipolar cells [nTPM]":"99.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"106.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"65.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"606.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"81.5","Single Cell Type RNA - Club cells [nTPM]":"156.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"252.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"77.4","Single Cell Type RNA - dendritic cells [nTPM]":"127.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"58.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"178.1","Single Cell Type RNA - Ductal cells [nTPM]":"80.7","Single Cell Type RNA - Early spermatids [nTPM]":"407.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"142.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"116.4","Single Cell Type RNA - Endothelial cells [nTPM]":"131.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"136.9","Single Cell Type RNA - Erythroid cells [nTPM]":"52.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"76.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"52.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"86.8","Single Cell Type RNA - Fibroblasts [nTPM]":"163.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"78.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"110.3","Single Cell Type RNA - granulocytes [nTPM]":"185.0","Single Cell Type RNA - Granulosa cells [nTPM]":"78.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"158.1","Single Cell Type RNA - Hepatocytes [nTPM]":"120.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"146.1","Single Cell Type RNA - Horizontal cells [nTPM]":"139.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"78.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"53.3","Single Cell Type RNA - Ionocytes [nTPM]":"136.3","Single Cell Type RNA - Kupffer cells [nTPM]":"176.2","Single Cell Type RNA - Langerhans cells [nTPM]":"171.1","Single Cell Type RNA - Late spermatids [nTPM]":"93.7","Single Cell Type RNA - Leydig cells [nTPM]":"133.6","Single Cell Type RNA - Macrophages [nTPM]":"151.1","Single Cell Type RNA - Melanocytes [nTPM]":"192.1","Single Cell Type RNA - Microglial cells [nTPM]":"46.9","Single Cell Type RNA - monocytes [nTPM]":"142.3","Single Cell Type RNA - Muller glia cells [nTPM]":"125.1","Single Cell Type RNA - NK-cells [nTPM]":"78.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"57.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"76.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"74.6","Single Cell Type RNA - Paneth cells [nTPM]":"51.5","Single Cell Type RNA - Peritubular cells [nTPM]":"190.7","Single Cell Type RNA - Plasma cells [nTPM]":"95.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"85.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"210.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"307.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.9","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"123.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"210.9","Single Cell Type RNA - Spermatocytes [nTPM]":"219.8","Single Cell Type RNA - Spermatogonia [nTPM]":"54.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"122.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"131.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"82.5","Single Cell Type RNA - T-cells [nTPM]":"117.3","Single Cell Type RNA - Theca cells [nTPM]":"184.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.9","Single Cell Type RNA - Urothelial cells [nTPM]":"112.8"},{"Gene":"SLC29A3","Gene synonym":["ENT3","FLJ11160"],"Ensembl":"ENSG00000198246","Gene description":"Solute carrier family 29 member 3","Uniprot":["Q9BZD2"],"Chromosome":"10","Position":"71319259-71381423","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"46.1","Extravillous trophoblasts":"45.3","Hofbauer cells":"34.7","Syncytiotrophoblasts":"31.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"31.8","Hep G2":"35.9","RT4":"29.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046085","HPA054976","HPA057905"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046085":"AB_2679531","HPA054976":"AB_2682659","HPA057905":"AB_2683550"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.07e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.53e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.16e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"2.6","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"4.8","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"7.3","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"4.4","Tissue RNA - duodenum [nTPM]":"2.1","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"2.4","Tissue RNA - hippocampal formation [nTPM]":"3.0","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"9.4","Tissue RNA - lung [nTPM]":"6.7","Tissue RNA - lymph node [nTPM]":"7.1","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"9.7","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"3.5","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"3.7","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"4.2","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"6.1","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"4.4","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"3.8","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"2.1","Cell RNA - A549 [nTPM]":"12.3","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"7.8","Cell RNA - ASC diff [nTPM]":"6.8","Cell RNA - ASC TERT1 [nTPM]":"5.3","Cell RNA - BEWO [nTPM]":"31.8","Cell RNA - BJ [nTPM]":"2.3","Cell RNA - BJ hTERT+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"13.8","Cell RNA - CAPAN-2 [nTPM]":"8.8","Cell RNA - Daudi [nTPM]":"7.4","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"4.7","Cell RNA - GAMG [nTPM]":"3.2","Cell RNA - HaCaT [nTPM]":"18.3","Cell RNA - HAP1 [nTPM]":"5.7","Cell RNA - HBEC3-KT [nTPM]":"2.9","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"5.6","Cell RNA - HEK 293 [nTPM]":"5.6","Cell RNA - HEL [nTPM]":"2.2","Cell RNA - HeLa [nTPM]":"1.0","Cell RNA - Hep G2 [nTPM]":"35.9","Cell RNA - HHSteC [nTPM]":"3.3","Cell RNA - HL-60 [nTPM]":"1.8","Cell RNA - HMC-1 [nTPM]":"4.5","Cell RNA - HSkMC [nTPM]":"5.2","Cell RNA - hTCEpi [nTPM]":"12.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"1.5","Cell RNA - HUVEC TERT2 [nTPM]":"3.2","Cell RNA - JURKAT [nTPM]":"8.5","Cell RNA - K-562 [nTPM]":"6.5","Cell RNA - Karpas-707 [nTPM]":"6.8","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"19.1","Cell RNA - MOLT-4 [nTPM]":"4.2","Cell RNA - NB-4 [nTPM]":"3.8","Cell RNA - NTERA-2 [nTPM]":"4.2","Cell RNA - OE19 [nTPM]":"19.2","Cell RNA - PC-3 [nTPM]":"4.5","Cell RNA - REH [nTPM]":"5.7","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"5.9","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"29.5","Cell RNA - SCLC-21H [nTPM]":"8.5","Cell RNA - SH-SY5Y [nTPM]":"9.6","Cell RNA - SiHa [nTPM]":"6.4","Cell RNA - SK-BR-3 [nTPM]":"20.3","Cell RNA - SK-MEL-30 [nTPM]":"1.7","Cell RNA - SuSa [nTPM]":"5.2","Cell RNA - T-47d [nTPM]":"3.2","Cell RNA - THP-1 [nTPM]":"4.0","Cell RNA - TIME [nTPM]":"5.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"2.3","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"1.8","Cell RNA - U-266\/84 [nTPM]":"3.1","Cell RNA - U-698 [nTPM]":"4.0","Cell RNA - U-87 MG [nTPM]":"7.6","Cell RNA - U-937 [nTPM]":"24.0","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"4.2","Blood RNA - classical monocyte [nTPM]":"19.3","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"5.4","Blood RNA - intermediate monocyte [nTPM]":"15.3","Blood RNA - MAIT T-cell [nTPM]":"4.6","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"4.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.1","Blood RNA - myeloid DC [nTPM]":"29.1","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.0","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"9.4","Blood RNA - non-classical monocyte [nTPM]":"10.3","Blood RNA - plasmacytoid DC [nTPM]":"20.2","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"9.5","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"3.0","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"4.2","Brain RNA - thalamus [nTPM]":"4.4","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"2.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"3.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"10.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"11.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.4","Single Cell Type RNA - Late spermatids [nTPM]":"15.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"10.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"8.5","Single Cell Type RNA - Muller glia cells [nTPM]":"3.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.9","Single Cell Type RNA - Paneth cells [nTPM]":"13.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"6.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"5.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.7","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"10.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"SMARCA4","Gene synonym":["BAF190","BRG1","FLJ39786","hSNF2b","SNF2","SNF2-BETA","SNF2L4","SNF2LB","SWI2"],"Ensembl":"ENSG00000127616","Gene description":"SWI\/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4","Uniprot":["P51532"],"Chromosome":"19","Position":"10960932-11079426","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Helicase","Hydrolase","Repressor","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"372.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004208","HPA048340"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center","Nucleoli rim"],"Antibody RRID":{"CAB004208":"AB_626762","HPA048340":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.8","Tissue RNA - adrenal gland [nTPM]":"16.2","Tissue RNA - amygdala [nTPM]":"14.4","Tissue RNA - appendix [nTPM]":"22.6","Tissue RNA - basal ganglia [nTPM]":"14.3","Tissue RNA - bone marrow [nTPM]":"31.8","Tissue RNA - breast [nTPM]":"13.0","Tissue RNA - cerebellum [nTPM]":"15.3","Tissue RNA - cerebral cortex [nTPM]":"23.7","Tissue RNA - cervix [nTPM]":"16.1","Tissue RNA - choroid plexus [nTPM]":"13.2","Tissue RNA - colon [nTPM]":"18.1","Tissue RNA - duodenum [nTPM]":"19.9","Tissue RNA - endometrium 1 [nTPM]":"14.5","Tissue RNA - epididymis [nTPM]":"9.5","Tissue RNA - esophagus [nTPM]":"32.9","Tissue RNA - fallopian tube [nTPM]":"20.8","Tissue RNA - gallbladder [nTPM]":"13.3","Tissue RNA - heart muscle [nTPM]":"16.2","Tissue RNA - hippocampal formation [nTPM]":"15.4","Tissue RNA - hypothalamus [nTPM]":"9.6","Tissue RNA - kidney [nTPM]":"15.7","Tissue RNA - liver [nTPM]":"8.6","Tissue RNA - lung [nTPM]":"17.9","Tissue RNA - lymph node [nTPM]":"27.0","Tissue RNA - medulla oblongata [nTPM]":"10.4","Tissue RNA - midbrain [nTPM]":"10.4","Tissue RNA - ovary [nTPM]":"14.9","Tissue RNA - pancreas [nTPM]":"18.3","Tissue RNA - parathyroid gland [nTPM]":"22.9","Tissue RNA - pituitary gland [nTPM]":"11.1","Tissue RNA - placenta [nTPM]":"20.2","Tissue RNA - pons [nTPM]":"11.0","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"12.9","Tissue RNA - retina [nTPM]":"19.7","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"23.7","Tissue RNA - skin 1 [nTPM]":"28.1","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"14.5","Tissue RNA - spinal cord [nTPM]":"3.9","Tissue RNA - spleen [nTPM]":"19.5","Tissue RNA - stomach 1 [nTPM]":"20.4","Tissue RNA - testis [nTPM]":"30.2","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"43.1","Tissue RNA - thyroid gland [nTPM]":"20.6","Tissue RNA - tongue [nTPM]":"13.9","Tissue RNA - tonsil [nTPM]":"23.7","Tissue RNA - urinary bladder [nTPM]":"17.4","Tissue RNA - vagina [nTPM]":"14.7","Tissue RNA - white matter [nTPM]":"19.3","Cell RNA - A-431 [nTPM]":"92.5","Cell RNA - A549 [nTPM]":"5.0","Cell RNA - AF22 [nTPM]":"157.2","Cell RNA - AN3-CA [nTPM]":"149.8","Cell RNA - ASC diff [nTPM]":"30.3","Cell RNA - ASC TERT1 [nTPM]":"25.4","Cell RNA - BEWO [nTPM]":"68.9","Cell RNA - BJ [nTPM]":"62.7","Cell RNA - BJ hTERT+ [nTPM]":"37.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"74.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"54.9","Cell RNA - CACO-2 [nTPM]":"126.9","Cell RNA - CAPAN-2 [nTPM]":"4.0","Cell RNA - Daudi [nTPM]":"215.4","Cell RNA - EFO-21 [nTPM]":"94.2","Cell RNA - fHDF\/TERT166 [nTPM]":"54.9","Cell RNA - GAMG [nTPM]":"3.0","Cell RNA - HaCaT [nTPM]":"65.9","Cell RNA - HAP1 [nTPM]":"123.6","Cell RNA - HBEC3-KT [nTPM]":"77.5","Cell RNA - HBF TERT88 [nTPM]":"40.8","Cell RNA - HDLM-2 [nTPM]":"89.5","Cell RNA - HEK 293 [nTPM]":"93.3","Cell RNA - HEL [nTPM]":"171.3","Cell RNA - HeLa [nTPM]":"76.5","Cell RNA - Hep G2 [nTPM]":"149.6","Cell RNA - HHSteC [nTPM]":"45.7","Cell RNA - HL-60 [nTPM]":"125.5","Cell RNA - HMC-1 [nTPM]":"82.0","Cell RNA - HSkMC [nTPM]":"43.1","Cell RNA - hTCEpi [nTPM]":"36.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.1","Cell RNA - hTERT-HME1 [nTPM]":"64.5","Cell RNA - hTERT-RPE1 [nTPM]":"33.3","Cell RNA - HUVEC TERT2 [nTPM]":"67.5","Cell RNA - JURKAT [nTPM]":"92.0","Cell RNA - K-562 [nTPM]":"156.7","Cell RNA - Karpas-707 [nTPM]":"78.3","Cell RNA - LHCN-M2 [nTPM]":"59.2","Cell RNA - MCF7 [nTPM]":"188.0","Cell RNA - MOLT-4 [nTPM]":"210.0","Cell RNA - NB-4 [nTPM]":"107.5","Cell RNA - NTERA-2 [nTPM]":"159.9","Cell RNA - OE19 [nTPM]":"45.1","Cell RNA - PC-3 [nTPM]":"134.7","Cell RNA - REH [nTPM]":"220.6","Cell RNA - RH-30 [nTPM]":"99.5","Cell RNA - RPMI-8226 [nTPM]":"111.7","Cell RNA - RPTEC TERT1 [nTPM]":"47.9","Cell RNA - RT4 [nTPM]":"114.8","Cell RNA - SCLC-21H [nTPM]":"177.8","Cell RNA - SH-SY5Y [nTPM]":"161.7","Cell RNA - SiHa [nTPM]":"66.6","Cell RNA - SK-BR-3 [nTPM]":"84.4","Cell RNA - SK-MEL-30 [nTPM]":"73.5","Cell RNA - SuSa [nTPM]":"50.1","Cell RNA - T-47d [nTPM]":"71.9","Cell RNA - THP-1 [nTPM]":"93.3","Cell RNA - TIME [nTPM]":"90.9","Cell RNA - U-138 MG [nTPM]":"110.3","Cell RNA - U-2 OS [nTPM]":"57.3","Cell RNA - U-2197 [nTPM]":"102.5","Cell RNA - U-251 MG [nTPM]":"104.9","Cell RNA - U-266\/70 [nTPM]":"160.6","Cell RNA - U-266\/84 [nTPM]":"192.2","Cell RNA - U-698 [nTPM]":"209.1","Cell RNA - U-87 MG [nTPM]":"62.6","Cell RNA - U-937 [nTPM]":"118.5","Cell RNA - WM-115 [nTPM]":"96.0","Blood RNA - basophil [nTPM]":"5.7","Blood RNA - classical monocyte [nTPM]":"5.8","Blood RNA - eosinophil [nTPM]":"6.4","Blood RNA - gdT-cell [nTPM]":"9.3","Blood RNA - intermediate monocyte [nTPM]":"6.9","Blood RNA - MAIT T-cell [nTPM]":"8.2","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"6.8","Blood RNA - memory CD8 T-cell [nTPM]":"7.9","Blood RNA - myeloid DC [nTPM]":"6.1","Blood RNA - naive B-cell [nTPM]":"6.8","Blood RNA - naive CD4 T-cell [nTPM]":"7.6","Blood RNA - naive CD8 T-cell [nTPM]":"7.5","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"8.5","Blood RNA - non-classical monocyte [nTPM]":"10.8","Blood RNA - plasmacytoid DC [nTPM]":"7.9","Blood RNA - T-reg [nTPM]":"6.4","Blood RNA - total PBMC [nTPM]":"4.7","Brain RNA - amygdala [nTPM]":"14.4","Brain RNA - basal ganglia [nTPM]":"14.3","Brain RNA - cerebellum [nTPM]":"15.3","Brain RNA - cerebral cortex [nTPM]":"23.7","Brain RNA - hippocampal formation [nTPM]":"15.4","Brain RNA - hypothalamus [nTPM]":"9.6","Brain RNA - medulla oblongata [nTPM]":"10.4","Brain RNA - midbrain [nTPM]":"10.4","Brain RNA - pons [nTPM]":"11.0","Brain RNA - spinal cord [nTPM]":"3.9","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"19.3","Single Cell Type RNA - Adipocytes [nTPM]":"25.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"72.6","Single Cell Type RNA - Astrocytes [nTPM]":"27.4","Single Cell Type RNA - B-cells [nTPM]":"28.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"43.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"43.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"91.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"28.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"372.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"62.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"70.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"65.9","Single Cell Type RNA - dendritic cells [nTPM]":"21.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"60.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"79.8","Single Cell Type RNA - Early spermatids [nTPM]":"53.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"58.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.2","Single Cell Type RNA - Endothelial cells [nTPM]":"58.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"63.2","Single Cell Type RNA - Erythroid cells [nTPM]":"41.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"61.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"57.3","Single Cell Type RNA - Fibroblasts [nTPM]":"43.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"50.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.5","Single Cell Type RNA - granulocytes [nTPM]":"30.4","Single Cell Type RNA - Granulosa cells [nTPM]":"75.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"21.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.3","Single Cell Type RNA - Horizontal cells [nTPM]":"101.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"47.7","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"23.8","Single Cell Type RNA - Langerhans cells [nTPM]":"21.5","Single Cell Type RNA - Late spermatids [nTPM]":"37.6","Single Cell Type RNA - Leydig cells [nTPM]":"26.1","Single Cell Type RNA - Macrophages [nTPM]":"30.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"43.8","Single Cell Type RNA - Muller glia cells [nTPM]":"36.1","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"76.4","Single Cell Type RNA - Paneth cells [nTPM]":"41.8","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"37.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"66.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"62.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"45.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"66.4","Single Cell Type RNA - Spermatocytes [nTPM]":"99.4","Single Cell Type RNA - Spermatogonia [nTPM]":"86.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"52.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"51.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"61.0","Single Cell Type RNA - T-cells [nTPM]":"30.4","Single Cell Type RNA - Theca cells [nTPM]":"68.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"60.5","Single Cell Type RNA - Urothelial cells [nTPM]":"50.1"},{"Gene":"SMARCB1","Gene synonym":["BAF47","hSNFS","Ini1","PPP1R144","RDT","Sfh1p","SNF5","SNF5L1","Snr1"],"Ensembl":"ENSG00000099956","Gene description":"SWI\/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1","Uniprot":["Q12824"],"Chromosome":"22","Position":"23786931-23838009","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Host-virus interaction","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Hypotrichosis","Mental retardation","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009196","HPA018248","HPA019127"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"CAB009196":"AB_2191983","HPA018248":"AB_1851162","HPA019127":"AB_1851165"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.52e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"35.9","Tissue RNA - adrenal gland [nTPM]":"46.4","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"40.3","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"10.0","Tissue RNA - cervix [nTPM]":"51.5","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"40.9","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"51.4","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"51.0","Tissue RNA - fallopian tube [nTPM]":"40.4","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"44.0","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"47.0","Tissue RNA - liver [nTPM]":"36.9","Tissue RNA - lung [nTPM]":"32.3","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"63.1","Tissue RNA - pancreas [nTPM]":"43.9","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"48.0","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"36.6","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"25.3","Tissue RNA - salivary gland [nTPM]":"44.1","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"48.1","Tissue RNA - skin 1 [nTPM]":"50.1","Tissue RNA - small intestine [nTPM]":"51.7","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"51.7","Tissue RNA - stomach 1 [nTPM]":"40.4","Tissue RNA - testis [nTPM]":"68.3","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"41.3","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"37.5","Tissue RNA - vagina [nTPM]":"40.9","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"2.4","Cell RNA - A549 [nTPM]":"1.6","Cell RNA - AF22 [nTPM]":"28.2","Cell RNA - AN3-CA [nTPM]":"2.6","Cell RNA - ASC diff [nTPM]":"2.7","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"5.8","Cell RNA - BJ [nTPM]":"9.2","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.3","Cell RNA - CACO-2 [nTPM]":"3.4","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"24.2","Cell RNA - EFO-21 [nTPM]":"7.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"6.9","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"4.5","Cell RNA - HDLM-2 [nTPM]":"4.1","Cell RNA - HEK 293 [nTPM]":"10.5","Cell RNA - HEL [nTPM]":"20.1","Cell RNA - HeLa [nTPM]":"3.2","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"3.0","Cell RNA - HL-60 [nTPM]":"21.7","Cell RNA - HMC-1 [nTPM]":"5.6","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"3.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.2","Cell RNA - hTERT-HME1 [nTPM]":"6.9","Cell RNA - hTERT-RPE1 [nTPM]":"1.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"3.0","Cell RNA - K-562 [nTPM]":"5.6","Cell RNA - Karpas-707 [nTPM]":"12.9","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"6.1","Cell RNA - MOLT-4 [nTPM]":"17.6","Cell RNA - NB-4 [nTPM]":"5.0","Cell RNA - NTERA-2 [nTPM]":"8.6","Cell RNA - OE19 [nTPM]":"7.2","Cell RNA - PC-3 [nTPM]":"5.7","Cell RNA - REH [nTPM]":"11.0","Cell RNA - RH-30 [nTPM]":"23.1","Cell RNA - RPMI-8226 [nTPM]":"10.8","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"4.5","Cell RNA - SCLC-21H [nTPM]":"13.4","Cell RNA - SH-SY5Y [nTPM]":"10.1","Cell RNA - SiHa [nTPM]":"2.2","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"17.9","Cell RNA - SuSa [nTPM]":"14.8","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"2.2","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"13.8","Cell RNA - U-266\/84 [nTPM]":"14.3","Cell RNA - U-698 [nTPM]":"17.7","Cell RNA - U-87 MG [nTPM]":"1.8","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"6.8","Blood RNA - basophil [nTPM]":"7.1","Blood RNA - classical monocyte [nTPM]":"12.8","Blood RNA - eosinophil [nTPM]":"6.4","Blood RNA - gdT-cell [nTPM]":"4.4","Blood RNA - intermediate monocyte [nTPM]":"13.4","Blood RNA - MAIT T-cell [nTPM]":"6.4","Blood RNA - memory B-cell [nTPM]":"24.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.7","Blood RNA - myeloid DC [nTPM]":"12.0","Blood RNA - naive B-cell [nTPM]":"9.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"9.8","Blood RNA - non-classical monocyte [nTPM]":"16.8","Blood RNA - plasmacytoid DC [nTPM]":"13.3","Blood RNA - T-reg [nTPM]":"10.4","Blood RNA - total PBMC [nTPM]":"8.1","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"10.0","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"33.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"120.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"73.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"85.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.2","Single Cell Type RNA - Bipolar cells [nTPM]":"55.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"37.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"120.6","Single Cell Type RNA - dendritic cells [nTPM]":"61.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"84.1","Single Cell Type RNA - Ductal cells [nTPM]":"94.6","Single Cell Type RNA - Early spermatids [nTPM]":"42.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.9","Single Cell Type RNA - Endothelial cells [nTPM]":"37.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"71.8","Single Cell Type RNA - Erythroid cells [nTPM]":"57.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"77.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"228.1","Single Cell Type RNA - Fibroblasts [nTPM]":"46.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.1","Single Cell Type RNA - granulocytes [nTPM]":"34.8","Single Cell Type RNA - Granulosa cells [nTPM]":"112.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.0","Single Cell Type RNA - Hepatocytes [nTPM]":"20.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"76.1","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"54.6","Single Cell Type RNA - Ionocytes [nTPM]":"99.7","Single Cell Type RNA - Kupffer cells [nTPM]":"23.0","Single Cell Type RNA - Langerhans cells [nTPM]":"41.7","Single Cell Type RNA - Late spermatids [nTPM]":"18.9","Single Cell Type RNA - Leydig cells [nTPM]":"35.8","Single Cell Type RNA - Macrophages [nTPM]":"36.5","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"51.2","Single Cell Type RNA - Muller glia cells [nTPM]":"92.4","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"74.7","Single Cell Type RNA - Paneth cells [nTPM]":"53.1","Single Cell Type RNA - Peritubular cells [nTPM]":"32.0","Single Cell Type RNA - Plasma cells [nTPM]":"139.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"74.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"62.8","Single Cell Type RNA - Spermatocytes [nTPM]":"138.9","Single Cell Type RNA - Spermatogonia [nTPM]":"163.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"64.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"53.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"160.1","Single Cell Type RNA - T-cells [nTPM]":"42.0","Single Cell Type RNA - Theca cells [nTPM]":"96.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"65.4","Single Cell Type RNA - Urothelial cells [nTPM]":"65.1"},{"Gene":"TP53","Gene synonym":["LFS1","p53"],"Ensembl":"ENSG00000141510","Gene description":"Tumor protein p53","Uniprot":["P04637"],"Chromosome":"17","Position":"7661779-7687538","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors","Transporters"],"Biological process":["Apoptosis","Biological rhythms","Cell cycle","Host-virus interaction","Necrosis","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002973","CAB039238","CAB039239","HPA051244","HPA063532","CAB072876","CAB079965"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria","Cytosol"],"Antibody RRID":{"CAB002973":"AB_2206626","CAB039238":null,"CAB039239":null,"CAB072876":"AB_2665731","CAB079965":null,"HPA051244":"AB_2681403","HPA063532":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.3","Tissue RNA - adrenal gland [nTPM]":"13.8","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"27.1","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"19.6","Tissue RNA - breast [nTPM]":"22.5","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"16.5","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"10.3","Tissue RNA - colon [nTPM]":"29.0","Tissue RNA - duodenum [nTPM]":"18.9","Tissue RNA - endometrium 1 [nTPM]":"24.5","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"28.8","Tissue RNA - fallopian tube [nTPM]":"31.3","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"11.1","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"11.4","Tissue RNA - kidney [nTPM]":"14.9","Tissue RNA - liver [nTPM]":"16.5","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"34.6","Tissue RNA - medulla oblongata [nTPM]":"18.7","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"27.3","Tissue RNA - pancreas [nTPM]":"18.3","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"27.5","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"15.3","Tissue RNA - skeletal muscle [nTPM]":"12.3","Tissue RNA - skin 1 [nTPM]":"37.4","Tissue RNA - small intestine [nTPM]":"20.4","Tissue RNA - smooth muscle [nTPM]":"24.6","Tissue RNA - spinal cord [nTPM]":"12.6","Tissue RNA - spleen [nTPM]":"31.1","Tissue RNA - stomach 1 [nTPM]":"22.6","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"12.3","Tissue RNA - thymus [nTPM]":"47.2","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"45.4","Tissue RNA - urinary bladder [nTPM]":"20.8","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"81.5","Cell RNA - A549 [nTPM]":"145.3","Cell RNA - AF22 [nTPM]":"81.1","Cell RNA - AN3-CA [nTPM]":"57.3","Cell RNA - ASC diff [nTPM]":"37.3","Cell RNA - ASC TERT1 [nTPM]":"43.9","Cell RNA - BEWO [nTPM]":"82.8","Cell RNA - BJ [nTPM]":"28.4","Cell RNA - BJ hTERT+ [nTPM]":"66.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"78.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"100.2","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"40.6","Cell RNA - Daudi [nTPM]":"190.5","Cell RNA - EFO-21 [nTPM]":"126.9","Cell RNA - fHDF\/TERT166 [nTPM]":"58.7","Cell RNA - GAMG [nTPM]":"77.6","Cell RNA - HaCaT [nTPM]":"174.9","Cell RNA - HAP1 [nTPM]":"119.7","Cell RNA - HBEC3-KT [nTPM]":"80.4","Cell RNA - HBF TERT88 [nTPM]":"72.8","Cell RNA - HDLM-2 [nTPM]":"42.7","Cell RNA - HEK 293 [nTPM]":"76.5","Cell RNA - HEL [nTPM]":"77.6","Cell RNA - HeLa [nTPM]":"76.8","Cell RNA - Hep G2 [nTPM]":"70.9","Cell RNA - HHSteC [nTPM]":"111.5","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"37.0","Cell RNA - HSkMC [nTPM]":"55.7","Cell RNA - hTCEpi [nTPM]":"93.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.9","Cell RNA - hTERT-HME1 [nTPM]":"106.5","Cell RNA - hTERT-RPE1 [nTPM]":"45.6","Cell RNA - HUVEC TERT2 [nTPM]":"79.4","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"3.8","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"41.5","Cell RNA - MCF7 [nTPM]":"145.1","Cell RNA - MOLT-4 [nTPM]":"130.0","Cell RNA - NB-4 [nTPM]":"96.3","Cell RNA - NTERA-2 [nTPM]":"80.2","Cell RNA - OE19 [nTPM]":"10.4","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"252.2","Cell RNA - RH-30 [nTPM]":"56.1","Cell RNA - RPMI-8226 [nTPM]":"66.2","Cell RNA - RPTEC TERT1 [nTPM]":"59.4","Cell RNA - RT4 [nTPM]":"87.3","Cell RNA - SCLC-21H [nTPM]":"46.0","Cell RNA - SH-SY5Y [nTPM]":"80.5","Cell RNA - SiHa [nTPM]":"94.1","Cell RNA - SK-BR-3 [nTPM]":"62.6","Cell RNA - SK-MEL-30 [nTPM]":"24.3","Cell RNA - SuSa [nTPM]":"39.4","Cell RNA - T-47d [nTPM]":"109.2","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"100.7","Cell RNA - U-138 MG [nTPM]":"91.6","Cell RNA - U-2 OS [nTPM]":"30.2","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"48.3","Cell RNA - U-266\/70 [nTPM]":"47.6","Cell RNA - U-266\/84 [nTPM]":"37.9","Cell RNA - U-698 [nTPM]":"82.5","Cell RNA - U-87 MG [nTPM]":"23.6","Cell RNA - U-937 [nTPM]":"9.7","Cell RNA - WM-115 [nTPM]":"80.1","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"21.2","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"21.7","Blood RNA - MAIT T-cell [nTPM]":"15.9","Blood RNA - memory B-cell [nTPM]":"21.5","Blood RNA - memory CD4 T-cell [nTPM]":"13.3","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"30.3","Blood RNA - naive B-cell [nTPM]":"19.1","Blood RNA - naive CD4 T-cell [nTPM]":"13.7","Blood RNA - naive CD8 T-cell [nTPM]":"15.4","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"17.5","Blood RNA - non-classical monocyte [nTPM]":"19.3","Blood RNA - plasmacytoid DC [nTPM]":"27.3","Blood RNA - T-reg [nTPM]":"17.3","Blood RNA - total PBMC [nTPM]":"14.7","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"16.5","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"11.4","Brain RNA - medulla oblongata [nTPM]":"18.7","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"12.6","Brain RNA - thalamus [nTPM]":"12.3","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"21.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"15.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.9","Single Cell Type RNA - dendritic cells [nTPM]":"24.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"24.8","Single Cell Type RNA - Early spermatids [nTPM]":"12.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"24.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.7","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.6","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"31.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"18.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"27.8","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"19.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"31.9","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.8","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - T-cells [nTPM]":"16.5","Single Cell Type RNA - Theca cells [nTPM]":"27.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.1","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"}]