Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [nTPM]"	"Tissue RNA - adrenal gland [nTPM]"	"Tissue RNA - amygdala [nTPM]"	"Tissue RNA - appendix [nTPM]"	"Tissue RNA - basal ganglia [nTPM]"	"Tissue RNA - bone marrow [nTPM]"	"Tissue RNA - breast [nTPM]"	"Tissue RNA - cerebellum [nTPM]"	"Tissue RNA - cerebral cortex [nTPM]"	"Tissue RNA - cervix [nTPM]"	"Tissue RNA - choroid plexus [nTPM]"	"Tissue RNA - colon [nTPM]"	"Tissue RNA - duodenum [nTPM]"	"Tissue RNA - endometrium 1 [nTPM]"	"Tissue RNA - epididymis [nTPM]"	"Tissue RNA - esophagus [nTPM]"	"Tissue RNA - fallopian tube [nTPM]"	"Tissue RNA - gallbladder [nTPM]"	"Tissue RNA - heart muscle [nTPM]"	"Tissue RNA - hippocampal formation [nTPM]"	"Tissue RNA - hypothalamus [nTPM]"	"Tissue RNA - kidney [nTPM]"	"Tissue RNA - liver [nTPM]"	"Tissue RNA - lung [nTPM]"	"Tissue RNA - lymph node [nTPM]"	"Tissue RNA - medulla oblongata [nTPM]"	"Tissue RNA - midbrain [nTPM]"	"Tissue RNA - ovary [nTPM]"	"Tissue RNA - pancreas [nTPM]"	"Tissue RNA - parathyroid gland [nTPM]"	"Tissue RNA - pituitary gland [nTPM]"	"Tissue RNA - placenta [nTPM]"	"Tissue RNA - pons [nTPM]"	"Tissue RNA - prostate [nTPM]"	"Tissue RNA - rectum [nTPM]"	"Tissue RNA - retina [nTPM]"	"Tissue RNA - salivary gland [nTPM]"	"Tissue RNA - seminal vesicle [nTPM]"	"Tissue RNA - skeletal muscle [nTPM]"	"Tissue RNA - skin 1 [nTPM]"	"Tissue RNA - small intestine [nTPM]"	"Tissue RNA - smooth muscle [nTPM]"	"Tissue RNA - spinal cord [nTPM]"	"Tissue RNA - spleen [nTPM]"	"Tissue RNA - stomach 1 [nTPM]"	"Tissue RNA - testis [nTPM]"	"Tissue RNA - thalamus [nTPM]"	"Tissue RNA - thymus [nTPM]"	"Tissue RNA - thyroid gland [nTPM]"	"Tissue RNA - tongue [nTPM]"	"Tissue RNA - tonsil [nTPM]"	"Tissue RNA - urinary bladder [nTPM]"	"Tissue RNA - vagina [nTPM]"	"Tissue RNA - white matter [nTPM]"	"Cell RNA - A-431 [nTPM]"	"Cell RNA - A549 [nTPM]"	"Cell RNA - AF22 [nTPM]"	"Cell RNA - AN3-CA [nTPM]"	"Cell RNA - ASC diff [nTPM]"	"Cell RNA - ASC TERT1 [nTPM]"	"Cell RNA - BEWO [nTPM]"	"Cell RNA - BJ [nTPM]"	"Cell RNA - BJ hTERT+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]"	"Cell RNA - CACO-2 [nTPM]"	"Cell RNA - CAPAN-2 [nTPM]"	"Cell RNA - Daudi [nTPM]"	"Cell RNA - EFO-21 [nTPM]"	"Cell RNA - fHDF/TERT166 [nTPM]"	"Cell RNA - GAMG [nTPM]"	"Cell RNA - HaCaT [nTPM]"	"Cell RNA - HAP1 [nTPM]"	"Cell RNA - HBEC3-KT [nTPM]"	"Cell RNA - HBF TERT88 [nTPM]"	"Cell RNA - HDLM-2 [nTPM]"	"Cell RNA - HEK 293 [nTPM]"	"Cell RNA - HEL [nTPM]"	"Cell RNA - HeLa [nTPM]"	"Cell RNA - Hep G2 [nTPM]"	"Cell RNA - HHSteC [nTPM]"	"Cell RNA - HL-60 [nTPM]"	"Cell RNA - HMC-1 [nTPM]"	"Cell RNA - HSkMC [nTPM]"	"Cell RNA - hTCEpi [nTPM]"	"Cell RNA - hTEC/SVTERT24-B [nTPM]"	"Cell RNA - hTERT-HME1 [nTPM]"	"Cell RNA - hTERT-RPE1 [nTPM]"	"Cell RNA - HUVEC TERT2 [nTPM]"	"Cell RNA - JURKAT [nTPM]"	"Cell RNA - K-562 [nTPM]"	"Cell RNA - Karpas-707 [nTPM]"	"Cell RNA - LHCN-M2 [nTPM]"	"Cell RNA - MCF7 [nTPM]"	"Cell RNA - MOLT-4 [nTPM]"	"Cell RNA - NB-4 [nTPM]"	"Cell RNA - NTERA-2 [nTPM]"	"Cell RNA - OE19 [nTPM]"	"Cell RNA - PC-3 [nTPM]"	"Cell RNA - REH [nTPM]"	"Cell RNA - RH-30 [nTPM]"	"Cell RNA - RPMI-8226 [nTPM]"	"Cell RNA - RPTEC TERT1 [nTPM]"	"Cell RNA - RT4 [nTPM]"	"Cell RNA - SCLC-21H [nTPM]"	"Cell RNA - SH-SY5Y [nTPM]"	"Cell RNA - SiHa [nTPM]"	"Cell RNA - SK-BR-3 [nTPM]"	"Cell RNA - SK-MEL-30 [nTPM]"	"Cell RNA - SuSa [nTPM]"	"Cell RNA - T-47d [nTPM]"	"Cell RNA - THP-1 [nTPM]"	"Cell RNA - TIME [nTPM]"	"Cell RNA - U-138 MG [nTPM]"	"Cell RNA - U-2 OS [nTPM]"	"Cell RNA - U-2197 [nTPM]"	"Cell RNA - U-251 MG [nTPM]"	"Cell RNA - U-266/70 [nTPM]"	"Cell RNA - U-266/84 [nTPM]"	"Cell RNA - U-698 [nTPM]"	"Cell RNA - U-87 MG [nTPM]"	"Cell RNA - U-937 [nTPM]"	"Cell RNA - WM-115 [nTPM]"	"Blood RNA - basophil [nTPM]"	"Blood RNA - classical monocyte [nTPM]"	"Blood RNA - eosinophil [nTPM]"	"Blood RNA - gdT-cell [nTPM]"	"Blood RNA - intermediate monocyte [nTPM]"	"Blood RNA - MAIT T-cell [nTPM]"	"Blood RNA - memory B-cell [nTPM]"	"Blood RNA - memory CD4 T-cell [nTPM]"	"Blood RNA - memory CD8 T-cell [nTPM]"	"Blood RNA - myeloid DC [nTPM]"	"Blood RNA - naive B-cell [nTPM]"	"Blood RNA - naive CD4 T-cell [nTPM]"	"Blood RNA - naive CD8 T-cell [nTPM]"	"Blood RNA - neutrophil [nTPM]"	"Blood RNA - NK-cell [nTPM]"	"Blood RNA - non-classical monocyte [nTPM]"	"Blood RNA - plasmacytoid DC [nTPM]"	"Blood RNA - T-reg [nTPM]"	"Blood RNA - total PBMC [nTPM]"	"Brain RNA - amygdala [nTPM]"	"Brain RNA - basal ganglia [nTPM]"	"Brain RNA - cerebellum [nTPM]"	"Brain RNA - cerebral cortex [nTPM]"	"Brain RNA - hippocampal formation [nTPM]"	"Brain RNA - hypothalamus [nTPM]"	"Brain RNA - medulla oblongata [nTPM]"	"Brain RNA - midbrain [nTPM]"	"Brain RNA - pons [nTPM]"	"Brain RNA - spinal cord [nTPM]"	"Brain RNA - thalamus [nTPM]"	"Brain RNA - white matter [nTPM]"	"Single Cell Type RNA - Adipocytes [nTPM]"	"Single Cell Type RNA - Alveolar cells type 1 [nTPM]"	"Single Cell Type RNA - Alveolar cells type 2 [nTPM]"	"Single Cell Type RNA - Astrocytes [nTPM]"	"Single Cell Type RNA - B-cells [nTPM]"	"Single Cell Type RNA - Basal keratinocytes [nTPM]"	"Single Cell Type RNA - Basal prostatic cells [nTPM]"	"Single Cell Type RNA - Basal respiratory cells [nTPM]"	"Single Cell Type RNA - Basal squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Bipolar cells [nTPM]"	"Single Cell Type RNA - Breast glandular cells [nTPM]"	"Single Cell Type RNA - Breast myoepithelial cells [nTPM]"	"Single Cell Type RNA - Cardiomyocytes [nTPM]"	"Single Cell Type RNA - Cholangiocytes [nTPM]"	"Single Cell Type RNA - Club cells [nTPM]"	"Single Cell Type RNA - Collecting duct cells [nTPM]"	"Single Cell Type RNA - Cone photoreceptor cells [nTPM]"	"Single Cell Type RNA - Cytotrophoblasts [nTPM]"	"Single Cell Type RNA - dendritic cells [nTPM]"	"Single Cell Type RNA - Distal enterocytes [nTPM]"	"Single Cell Type RNA - Distal tubular cells [nTPM]"	"Single Cell Type RNA - Ductal cells [nTPM]"	"Single Cell Type RNA - Early spermatids [nTPM]"	"Single Cell Type RNA - Endometrial ciliated cells [nTPM]"	"Single Cell Type RNA - Endometrial stromal cells [nTPM]"	"Single Cell Type RNA - Endothelial cells [nTPM]"	"Single Cell Type RNA - Enteroendocrine cells [nTPM]"	"Single Cell Type RNA - Erythroid cells [nTPM]"	"Single Cell Type RNA - Excitatory neurons [nTPM]"	"Single Cell Type RNA - Exocrine glandular cells [nTPM]"	"Single Cell Type RNA - Extravillous trophoblasts [nTPM]"	"Single Cell Type RNA - Fibroblasts [nTPM]"	"Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]"	"Single Cell Type RNA - Glandular and luminal cells [nTPM]"	"Single Cell Type RNA - granulocytes [nTPM]"	"Single Cell Type RNA - Granulosa cells [nTPM]"	"Single Cell Type RNA - Hepatic stellate cells [nTPM]"	"Single Cell Type RNA - Hepatocytes [nTPM]"	"Single Cell Type RNA - Hofbauer cells [nTPM]"	"Single Cell Type RNA - Horizontal cells [nTPM]"	"Single Cell Type RNA - Inhibitory neurons [nTPM]"	"Single Cell Type RNA - Intestinal goblet cells [nTPM]"	"Single Cell Type RNA - Ionocytes [nTPM]"	"Single Cell Type RNA - Kupffer cells [nTPM]"	"Single Cell Type RNA - Langerhans cells [nTPM]"	"Single Cell Type RNA - Late spermatids [nTPM]"	"Single Cell Type RNA - Leydig cells [nTPM]"	"Single Cell Type RNA - Macrophages [nTPM]"	"Single Cell Type RNA - Melanocytes [nTPM]"	"Single Cell Type RNA - Microglial cells [nTPM]"	"Single Cell Type RNA - monocytes [nTPM]"	"Single Cell Type RNA - Muller glia cells [nTPM]"	"Single Cell Type RNA - NK-cells [nTPM]"	"Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]"	"Single Cell Type RNA - Oligodendrocytes [nTPM]"	"Single Cell Type RNA - Pancreatic endocrine cells [nTPM]"	"Single Cell Type RNA - Paneth cells [nTPM]"	"Single Cell Type RNA - Peritubular cells [nTPM]"	"Single Cell Type RNA - Plasma cells [nTPM]"	"Single Cell Type RNA - Prostatic glandular cells [nTPM]"	"Single Cell Type RNA - Proximal enterocytes [nTPM]"	"Single Cell Type RNA - Proximal tubular cells [nTPM]"	"Single Cell Type RNA - Respiratory ciliated cells [nTPM]"	"Single Cell Type RNA - Rod photoreceptor cells [nTPM]"	"Single Cell Type RNA - Sertoli cells [nTPM]"	"Single Cell Type RNA - Skeletal myocytes [nTPM]"	"Single Cell Type RNA - Smooth muscle cells [nTPM]"	"Single Cell Type RNA - Spermatocytes [nTPM]"	"Single Cell Type RNA - Spermatogonia [nTPM]"	"Single Cell Type RNA - Squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Suprabasal keratinocytes [nTPM]"	"Single Cell Type RNA - Syncytiotrophoblasts [nTPM]"	"Single Cell Type RNA - T-cells [nTPM]"	"Single Cell Type RNA - Theca cells [nTPM]"	"Single Cell Type RNA - Undifferentiated cells [nTPM]"	"Single Cell Type RNA - Urothelial cells [nTPM]"
CHEK2	"bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53"	ENSG00000183765	"Checkpoint kinase 2"	O96017	22	28687743-28742422	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Spermatogonia: 31.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA001878, CAB002030"	Enhanced		Supported	"Nucleoplasm,Golgi apparatus"		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	"Golgi apparatus"	"CAB002030: AB_563660, HPA001878: AB_1078514"	"unprognostic (1.54e-1)"	"unprognostic (2.20e-1)"	"unprognostic (5.83e-2)"	"unprognostic (2.93e-2)"	"unprognostic (2.42e-1)"	"unprognostic (3.83e-2)"	"unprognostic (1.49e-3)"	"unprognostic (5.08e-3)"	"unprognostic (3.33e-3)"	"unprognostic (9.62e-3)"	"unprognostic (1.28e-2)"	"unprognostic (3.13e-1)"	"prognostic unfavorable (7.80e-9)"	"unprognostic (2.38e-2)"	"unprognostic (1.78e-1)"	"unprognostic (7.27e-2)"	"unprognostic (6.79e-3)"	4.5	6.2	2.4	8.8	2.5	15.4	5.8	2.4	3.7	5.0	2.8	8.8	6.3	4.1	7.3	7.2	3.7	4.7	4.2	2.3	2.8	4.5	6.3	4.4	12.1	2.6	2.6	8.2	2.3	1.3	2.7	7.8	2.8	4.1	10.9	0.4	3.2	3.8	1.3	6.7	7.0	4.8	2.6	6.7	4.1	8.5	2.8	9.4	3.3	1.1	12.0	6.8	5.0	2.9	30.7	9.7	31.1	32.4	10.1	42.7	18.7	15.2	19.9	18.7	27.8	29.1	21.8	36.3	13.0	11.5	21.6	32.1	42.7	29.0	25.0	24.6	31.2	45.3	25.5	46.2	9.4	33.4	38.0	18.6	13.5	25.0	23.0	14.1	25.4	29.4	30.5	33.9	19.8	39.2	24.6	61.5	40.6	41.3	21.6	52.6	18.2	42.7	17.1	11.2	17.8	9.7	16.7	31.4	17.4	22.8	22.6	32.2	7.8	17.1	19.4	14.3	9.1	21.8	28.3	65.4	17.1	34.9	21.0	9.9	4.0	1.2	1.1	8.1	2.4	11.9	2.1	2.1	8.2	7.8	4.0	2.6	0.6	3.4	4.1	6.1	2.8	3.6	2.4	2.5	2.4	3.7	2.3	2.8	2.6	2.6	2.8	2.6	2.8	2.9	2.3	9.6	4.8	2.9	5.5	6.4	5.3	8.3	8.6	1.1	3.2	3.9	1.8	0.0	5.0	1.8	0.0	15.4	1.1	3.8	0.0	1.8	7.0	2.9	10.1	3.0	1.2	11.2	2.9	1.4	13.6	12.4	5.1	7.0	3.8	7.4	2.5	1.3	9.7	0.0	1.2	5.3	8.2	2.4	8.5	1.2	6.2	5.1	1.8	2.8	3.9	0.8	6.2	0.0	1.0	1.0	4.7	4.5	11.4	2.7	3.0	3.9	2.9	1.1	0.0	10.2	3.0	6.7	31.2	8.3	2.3	3.4	3.3	5.7	10.0	4.5
CHRM3		ENSG00000133019	"Cholinergic receptor muscarinic 3"	P20309	1	239386565-239915452	"Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins"		"G-protein coupled receptor, Receptor, Transducer"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 11.8;salivary gland: 17.5"	"Group enriched"	"Detected in many"	28	"Excitatory neurons: 802.9;Inhibitory neurons: 624.0"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"RPMI-8226: 17.2;SH-SY5Y: 53.5;U-266/70: 21.7;U-266/84: 16.3"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"HPA024106, HPA048036"	Approved		Supported	"Plasma membrane"		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 22: Non-specific - Unknown function"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	"Plasma membrane"		"HPA024106: AB_1854211, HPA048036: AB_2680238"	"unprognostic (1.63e-1)"	"unprognostic (4.82e-2)"	"unprognostic (1.05e-1)"	"unprognostic (4.11e-3)"	"unprognostic (3.48e-3)"	"unprognostic (5.81e-2)"	"unprognostic (2.30e-3)"	"unprognostic (5.18e-2)"	"unprognostic (1.71e-1)"	"unprognostic (1.27e-1)"	"unprognostic (6.29e-2)"	"unprognostic (6.44e-2)"	"unprognostic (5.34e-4)"	"unprognostic (3.04e-2)"	"unprognostic (2.67e-1)"	"unprognostic (1.02e-1)"	"unprognostic (4.88e-2)"	0.3	0.4	4.6	0.8	7.3	0.2	0.8	0.0	11.8	0.4	0.0	7.0	1.4	1.9	0.4	7.5	0.8	0.7	0.4	7.5	0.0	1.1	0.4	1.1	0.1	0.0	0.0	4.8	10.6	0.5	0.5	0.8	0.0	1.1	2.8	1.7	17.5	3.0	0.0	1.3	1.5	4.1	0.0	0.7	5.0	2.5	4.1	0.1	2.0	0.1	0.1	7.0	0.4	2.9	0.0	0.1	0.4	0.4	0.0	0.0	0.9	0.6	0.1	0.3	0.1	0.0	0.0	0.0	2.1	0.0	0.0	5.8	0.6	3.8	2.7	0.0	3.7	0.6	0.4	0.0	0.0	0.0	0.2	0.0	0.2	0.0	0.0	0.8	0.0	0.0	1.1	9.1	0.9	1.4	0.0	0.0	4.6	4.6	9.1	0.0	1.1	17.2	0.7	0.8	0.1	53.5	0.0	0.1	0.1	4.0	1.8	0.0	0.3	2.3	0.8	0.1	0.5	21.7	16.3	0.0	0.5	0.0	0.3	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.3	0.1	0.0	0.0	0.1	0.0	0.0	0.0	4.6	7.3	0.0	11.8	7.5	0.0	0.0	0.0	0.0	0.0	4.1	2.9	6.1	0.0	3.7	6.2	0.0	0.0	2.1	0.0	0.6	19.0	4.6	3.2	1.2	0.0	0.8	0.0	0.0	3.2	0.3	11.0	1.9	0.4	19.6	0.1	0.1	3.0	3.5	4.6	802.9	17.3	0.7	3.9	11.7	0.2	1.3	7.5	4.2	0.3	0.5	0.0	624.0	6.0	0.0	0.0	0.0	3.9	0.0	0.2	7.2	22.5	0.0	0.3	0.0	8.5	11.2	2.6	25.3	0.4	0.2	2.5	2.2	1.4	1.6	0.6	0.0	0.2	1.1	12.9	3.0	0.2	0.0	0.5	0.1	0.8	15.5	0.2
EDNRB	"ETB, HSCR, HSCR2"	ENSG00000136160	"Endothelin receptor type B"	P24530	13	77895481-77975529	"Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins"		"G-protein coupled receptor, Receptor, Transducer"	"Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"placenta: 127.8"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 120.5;Astrocytes: 126.3;Hepatic stellate cells: 112.5;Melanocytes: 110.3;Muller glia cells: 116.2;Sertoli cells: 216.9;Skeletal myocytes: 81.3;Smooth muscle cells: 102.1"	"Cancer enhanced"	"Detected in all"		"melanoma: 127.7"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"AF22: 68.0;ASC diff: 50.5;SK-MEL-30: 66.0;U-266/70: 40.7;WM-115: 131.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017842, HPA027546"	Approved		Supported	"Plasma membrane,Cytosol"		NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 17: WM-115 - Nervous system development"	"Cluster 48: Smooth muscle cells - ECM organization"	"Plasma membrane"	Cytosol	"CAB017842: , HPA027546: AB_2672327"	"unprognostic (7.75e-2)"	"unprognostic (6.73e-2)"	"unprognostic (1.41e-3)"	"unprognostic (2.59e-2)"	"unprognostic (8.37e-2)"	"unprognostic (2.45e-3)"	"unprognostic (4.17e-3)"	"unprognostic (5.43e-2)"	"unprognostic (1.02e-1)"	"unprognostic (1.38e-2)"	"unprognostic (3.40e-2)"	"unprognostic (3.01e-2)"	"prognostic favorable (7.20e-5)"	"unprognostic (1.59e-2)"	"unprognostic (3.86e-2)"	"unprognostic (4.58e-2)"	"unprognostic (6.77e-3)"	58.8	41.2	34.7	19.5	50.8	0.9	39.8	44.6	26.1	18.7	6.7	13.0	20.0	13.1	3.7	8.2	14.1	14.9	28.1	27.5	51.6	33.0	50.9	51.2	10.4	76.2	66.0	4.7	11.4	15.3	9.6	127.8	47.9	25.3	13.2	17.9	27.0	6.9	11.3	12.5	21.9	12.9	97.2	16.8	10.6	2.3	64.9	4.0	31.8	18.8	4.7	23.6	15.5	78.7	5.7	0.0	68.0	0.0	50.5	2.0	1.0	0.0	0.1	0.0	0.0	25.9	0.0	0.0	2.6	0.0	0.1	0.2	0.0	0.0	0.0	0.3	0.3	0.3	0.0	0.0	3.5	0.0	0.2	13.2	0.0	0.0	0.0	0.1	0.6	0.0	0.2	0.2	1.7	0.0	0.0	0.3	0.0	0.0	0.0	0.2	0.0	0.1	0.7	0.1	0.1	0.5	0.1	0.0	66.0	8.9	0.0	0.3	0.3	0.6	0.1	0.0	0.4	40.7	24.9	0.1	1.2	0.0	131.8	0.0	0.4	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	34.7	50.8	44.6	26.1	27.5	51.6	76.2	66.0	47.9	97.2	64.9	78.7	120.5	12.8	51.0	126.3	0.2	14.8	1.0	0.0	1.2	5.8	1.2	2.8	10.8	0.0	2.5	0.0	6.2	14.7	0.3	0.1	0.0	0.0	2.9	2.9	20.7	73.3	0.0	0.0	1.3	0.0	13.9	51.1	1.1	35.9	6.3	2.1	112.5	1.1	13.4	0.0	1.6	0.0	0.0	18.7	10.6	2.2	79.9	5.2	110.3	6.5	0.1	116.2	0.0	48.2	0.9	0.1	0.0	2.6	0.1	2.6	0.0	0.1	1.5	4.4	216.9	81.3	102.1	0.4	2.1	0.2	7.2	5.7	1.6	2.5	0.0	1.5
EPCAM	"17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1"	ENSG00000119888	"Epithelial cell adhesion molecule"	P16422	2	47345158-47387601	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Tumor antigen"	"Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 806.0"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 2317.0;Ductal cells: 999.6;Intestinal goblet cells: 1378.2;Paneth cells: 2437.0;Proximal enterocytes: 2681.1;Undifferentiated cells: 1607.7"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"A-431: 538.9;CACO-2: 680.9;CAPAN-2: 944.4;OE19: 911.8;RPTEC TERT1: 398.6"	"Low region specificity"	"Detected in some"			"Low region specificity"	"Detected in many"			"CAB003809, HPA026761, CAB030012, CAB055098, HPA067463"	Enhanced		Supported	"Plasma membrane"		NA	NA		22000		"Cluster 9: Intestine - Unknown function"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Plasma membrane"		"CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846"	"unprognostic (6.79e-2)"	"unprognostic (2.28e-1)"	"unprognostic (1.59e-2)"	"unprognostic (1.16e-2)"	"unprognostic (1.61e-1)"	"unprognostic (3.49e-2)"	"unprognostic (2.01e-1)"	"unprognostic (3.61e-2)"	"unprognostic (3.40e-1)"	"prognostic favorable (3.30e-4)"	"unprognostic (5.27e-2)"	"unprognostic (3.28e-2)"	"prognostic favorable (1.04e-6)"	"unprognostic (6.38e-3)"	"unprognostic (1.28e-1)"	"unprognostic (6.45e-3)"	"unprognostic (6.08e-2)"	4.4	12.2	3.1	77.0	4.0	10.2	99.7	1.5	3.1	116.2	1.0	806.0	726.5	33.0	238.9	10.8	114.3	71.1	0.6	3.3	9.2	223.1	3.1	74.7	0.9	2.8	3.2	1.2	125.4	219.5	86.9	1.7	3.4	60.5	751.0	0.6	119.8	52.8	0.1	8.8	769.6	22.2	2.6	1.4	172.4	21.7	10.4	6.4	286.8	0.1	2.8	30.9	4.2	2.6	538.9	5.4	0.4	1.2	0.0	0.0	321.3	0.2	0.0	0.6	0.0	680.9	944.4	0.1	141.5	1.0	0.4	247.3	4.6	62.2	2.0	0.1	56.3	0.3	2.5	261.6	0.1	0.3	0.4	0.0	17.6	0.0	0.0	0.0	0.8	0.0	160.9	0.0	0.3	269.7	0.5	24.0	164.3	911.8	31.4	0.3	0.0	136.9	398.6	231.3	354.0	3.2	4.3	187.7	0.6	132.7	158.3	1.0	0.7	0.3	6.3	2.0	1.1	39.2	0.6	0.8	0.5	0.2	0.3	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	3.1	4.0	1.5	3.1	3.3	9.2	2.8	3.2	3.4	2.6	10.4	2.6	3.7	310.9	148.1	1.3	7.0	9.3	227.6	127.4	14.2	0.5	184.7	112.9	2.0	243.1	222.8	448.8	0.0	16.4	2.3	2317.0	76.3	999.6	8.6	434.7	35.3	5.8	498.1	23.1	1.1	402.8	6.5	6.3	150.3	445.3	32.5	11.8	1.4	0.6	2.9	0.0	0.4	1378.2	486.2	0.0	5.2	5.6	20.5	5.6	35.6	0.0	11.5	15.7	0.0	0.5	1.2	617.5	2437.0	18.8	1.8	257.9	2681.1	195.9	219.0	0.7	13.1	0.5	13.7	83.5	130.3	33.3	10.4	6.0	9.4	70.3	1607.7	230.7
FH		ENSG00000091483	"Fumarate hydratase"	P07954	1	241497603-241519755	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, Tricarboxylic acid cycle"	Lyase	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 276.4"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 173.5;Early spermatids: 226.0;Syncytiotrophoblasts: 166.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017785, HPA025770, HPA025948, HPA027341"	Enhanced	Supported	Enhanced	Mitochondria		NA	NA		1800000	"Cluster 44: Non-specific - Transcription"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria		"CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222"	"unprognostic (1.03e-2)"	"unprognostic (3.82e-2)"	"unprognostic (9.46e-3)"	"unprognostic (2.18e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.07e-1)"	"unprognostic (2.28e-2)"	"unprognostic (1.55e-1)"	"unprognostic (5.14e-2)"	"unprognostic (1.85e-2)"	"unprognostic (1.27e-2)"	"unprognostic (1.09e-1)"	"prognostic favorable (2.76e-7)"	"unprognostic (1.05e-1)"	"unprognostic (1.05e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.24e-2)"	43.4	75.2	30.4	31.0	33.3	31.4	37.3	33.5	42.0	28.9	43.9	66.8	68.2	36.9	26.1	51.1	27.9	23.7	179.0	33.9	33.1	101.8	276.4	26.4	30.0	31.8	31.0	24.9	38.1	95.0	31.1	32.1	32.1	33.5	69.0	58.8	42.0	38.4	213.4	40.3	59.1	42.0	32.4	30.1	53.6	44.4	32.7	31.3	34.6	229.3	40.4	37.5	33.7	33.0	129.2	105.6	97.9	89.0	93.9	110.0	154.9	155.7	121.1	171.6	107.1	152.2	78.0	81.1	100.3	119.9	75.0	178.4	151.7	115.8	148.4	93.5	48.9	76.3	102.2	131.4	84.1	180.2	66.7	80.2	70.7	96.6	108.0	60.2	107.2	175.8	236.3	101.7	126.9	64.3	156.6	120.1	104.5	186.2	223.6	127.4	107.2	365.7	167.4	107.6	125.4	108.4	131.1	153.3	104.0	67.2	117.1	120.9	106.5	76.6	98.9	137.0	264.0	90.3	103.7	97.3	85.7	203.5	112.6	11.9	22.8	4.9	16.1	33.3	21.0	27.2	18.8	15.1	46.7	25.1	22.3	21.1	1.3	18.3	29.1	23.1	23.8	16.7	30.4	33.3	33.5	42.0	33.9	33.1	31.8	31.0	32.1	32.4	32.7	33.0	17.1	38.5	30.2	9.4	25.0	20.0	24.6	69.5	17.1	24.7	19.9	17.5	173.5	35.8	40.0	23.9	14.6	101.6	13.7	44.0	78.2	60.4	226.0	25.4	23.5	18.6	18.0	37.7	12.7	45.0	58.7	25.5	26.5	25.4	19.0	24.9	13.6	80.4	50.7	35.3	14.9	40.6	48.8	18.5	14.4	37.4	23.9	23.9	24.9	8.4	27.9	35.0	10.3	8.0	14.4	29.4	35.7	26.7	41.3	19.0	66.1	86.0	29.2	39.1	39.5	27.7	67.9	84.7	47.1	32.1	18.6	166.1	14.9	48.4	74.2	22.8
FLCN	"BHD, DENND8B, MGC17998, MGC23445"	ENSG00000154803	Folliculin	Q8NFG4	17	17212212-17237188	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"		"GTPase activation"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cone photoreceptor cells: 79.2;Erythroid cells: 81.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB015158, HPA028760"	Supported		Supported	"Plasma membrane,Cytosol"		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 72: Non-specific - Transcription"	"Cluster 18: U-2197 - ECM organization"	"Cluster 6: Erythroid cells - Oxygen transport"	Cytosol	"Plasma membrane"	"CAB015158: AB_2231645, HPA028760: AB_10601323"	"unprognostic (1.99e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.74e-1)"	"unprognostic (3.85e-2)"	"unprognostic (3.69e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.32e-1)"	"unprognostic (3.58e-2)"	"unprognostic (3.90e-1)"	"prognostic favorable (4.49e-4)"	"unprognostic (6.45e-3)"	"unprognostic (2.55e-3)"	"unprognostic (1.92e-1)"	"unprognostic (9.71e-2)"	"unprognostic (2.62e-2)"	"unprognostic (1.65e-1)"	21.8	19.0	19.0	10.7	25.9	17.7	18.9	27.3	31.6	42.5	18.3	43.7	23.3	37.0	14.5	13.8	25.2	17.0	29.2	31.9	14.0	15.3	28.9	26.8	12.4	21.3	15.2	35.3	15.2	13.1	28.6	13.1	22.0	27.1	10.2	7.2	16.4	13.7	42.7	19.3	26.8	14.5	14.0	29.2	22.4	21.0	19.3	8.6	23.8	18.4	8.0	28.2	25.5	28.3	12.0	30.4	11.5	14.9	36.4	20.6	15.8	11.8	19.1	18.0	24.3	24.3	10.4	6.3	13.8	14.0	40.2	14.4	14.0	7.3	9.3	10.9	12.2	12.4	9.1	13.9	33.6	4.9	33.5	30.3	24.0	27.6	20.8	16.4	14.8	9.2	17.7	16.4	17.6	17.5	8.3	8.4	11.2	17.8	8.1	16.9	52.7	7.3	11.0	14.1	13.6	8.8	11.6	7.5	19.3	70.7	11.1	8.8	15.7	40.6	16.6	56.5	14.1	7.7	7.4	5.7	26.0	10.8	16.6	2.4	2.8	1.6	1.6	3.7	2.2	3.6	1.9	1.4	1.4	3.2	2.1	1.9	6.0	2.8	1.4	1.4	2.9	1.8	19.0	25.9	27.3	31.6	31.9	14.0	21.3	15.2	22.0	14.0	19.3	28.3	8.4	25.6	12.6	17.0	9.2	18.4	12.7	5.7	2.8	20.7	13.2	6.5	23.7	14.3	6.2	7.3	79.2	10.9	5.3	25.0	1.9	12.3	14.5	16.8	11.3	12.5	25.7	81.7	31.3	8.3	7.4	20.6	9.7	15.2	1.3	10.3	27.8	24.1	16.6	47.1	23.7	11.0	16.2	21.6	19.2	20.4	28.0	13.2	10.6	18.7	12.2	13.3	6.2	17.1	32.4	9.8	15.6	20.3	4.4	11.6	36.8	6.1	9.1	18.5	19.7	24.8	11.1	6.3	10.8	5.3	18.2	33.8	10.0	16.3	12.6	13.0
MLH1	"COCA2, FCC2, HNPCC, HNPCC2"	ENSG00000076242	"MutL homolog 1"	P40692	3	36993350-37050846	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013294, HPA052707, HPA060714, CAB070868"	Supported		Enhanced	Nucleoplasm		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 66: Spermatocytes - Spermatogenesis"	Nucleoplasm		"CAB013294: AB_2533406, CAB070868: , HPA052707: AB_2681923, HPA060714: AB_2684348"	"unprognostic (1.26e-2)"	"unprognostic (3.88e-3)"	"unprognostic (2.36e-2)"	"unprognostic (1.82e-1)"	"unprognostic (3.33e-2)"	"unprognostic (1.05e-1)"	"prognostic unfavorable (8.24e-5)"	"unprognostic (3.36e-2)"	"unprognostic (2.18e-1)"	"unprognostic (1.32e-1)"	"unprognostic (8.54e-2)"	"unprognostic (8.63e-3)"	"unprognostic (2.10e-3)"	"unprognostic (4.37e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.02e-2)"	"unprognostic (8.86e-2)"	15.6	17.9	7.3	17.4	8.0	22.1	15.4	7.1	9.1	17.4	7.6	17.4	12.0	16.3	14.0	14.3	14.9	11.1	35.4	6.9	8.3	16.0	19.1	15.8	21.9	8.6	7.4	15.1	16.6	22.4	22.7	14.8	7.6	16.2	14.5	9.6	12.1	14.0	49.1	13.4	13.4	19.2	7.1	18.8	15.5	25.4	7.7	28.4	19.2	42.2	24.3	17.2	14.0	9.0	37.1	56.7	66.7	0.2	25.9	34.5	30.7	54.7	44.4	64.1	62.3	43.4	40.1	92.2	25.0	44.1	33.6	24.7	65.2	45.8	68.5	42.2	32.1	68.1	42.3	54.9	23.2	81.9	40.5	28.4	29.0	54.8	57.8	21.9	37.6	55.0	86.0	32.0	66.2	27.6	81.0	22.2	49.4	38.4	31.6	4.6	90.6	40.2	35.1	39.3	14.2	36.1	52.1	56.9	32.7	33.3	79.9	55.6	28.8	46.0	50.5	44.0	65.9	29.1	93.7	88.1	37.8	71.9	45.7	12.6	12.5	15.1	12.7	22.6	9.8	11.3	7.7	11.4	14.3	9.7	8.4	9.6	2.6	7.8	29.2	5.9	15.0	11.0	7.3	8.0	7.1	9.1	6.9	8.3	8.6	7.4	7.6	7.1	7.7	9.0	10.8	25.6	15.8	22.9	18.5	7.1	12.4	18.7	7.4	18.5	9.6	9.7	41.8	12.8	15.8	11.0	10.4	33.4	16.0	6.1	19.6	14.6	31.3	12.5	11.3	10.7	5.4	19.0	18.5	14.7	26.9	14.4	12.2	9.5	7.6	13.0	13.6	14.9	20.1	3.3	21.6	8.6	16.2	16.3	8.9	13.2	11.1	13.8	8.8	10.3	18.2	15.9	11.3	27.2	31.3	9.3	7.4	13.9	22.1	6.4	5.3	12.9	16.5	18.1	13.1	10.0	14.0	58.6	29.3	9.3	5.5	20.0	15.9	14.8	8.4	6.5
MLH3		ENSG00000119684	"MutL homolog 3"	Q9UHC1	14	75013769-75051532	"Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Disease variant, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Oligodendrocytes: 106.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA060570			Approved	Nucleoplasm		NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 51: Myeloid cells - Hemostasis"	Nucleoplasm		"HPA060570: AB_2684323"	"unprognostic (2.94e-1)"	"unprognostic (6.70e-3)"	"unprognostic (7.14e-3)"	"unprognostic (7.35e-2)"	"unprognostic (7.38e-2)"	"unprognostic (1.55e-1)"	"unprognostic (1.49e-2)"	"unprognostic (1.62e-2)"	"unprognostic (3.77e-2)"	"unprognostic (6.68e-2)"	"unprognostic (1.93e-2)"	"unprognostic (8.42e-2)"	"unprognostic (3.53e-1)"	"unprognostic (2.89e-1)"	"unprognostic (1.68e-1)"	"unprognostic (1.64e-1)"	"unprognostic (7.11e-2)"	4.3	9.4	7.2	5.6	11.7	2.3	7.9	12.7	8.6	7.2	5.8	5.8	5.3	7.4	7.5	5.3	6.5	6.1	6.0	6.3	9.3	7.5	7.3	5.2	6.6	8.1	8.8	8.1	5.3	12.6	5.1	5.8	9.3	7.6	6.6	8.5	5.4	8.6	6.6	4.7	4.8	5.5	7.9	6.4	4.5	6.7	9.0	6.4	11.1	7.8	7.7	5.3	3.2	19.8	13.1	13.5	10.3	1.7	10.6	17.0	10.4	4.5	4.2	7.0	6.3	11.7	16.5	14.2	3.7	5.5	9.2	9.2	0.2	4.3	10.4	14.1	0.2	9.3	8.7	7.1	8.6	4.0	6.3	6.3	10.4	7.2	0.5	8.7	12.0	0.1	8.8	11.4	15.8	11.3	6.3	4.5	8.7	10.6	7.6	11.3	6.3	3.1	17.4	13.4	14.9	10.5	14.4	9.9	0.9	10.3	13.1	9.0	6.1	2.9	5.9	4.3	4.5	14.4	15.0	15.4	10.7	0.4	13.2	5.1	2.6	1.7	4.6	2.1	3.5	3.0	2.5	4.2	2.9	5.9	4.1	3.3	1.1	6.3	1.5	2.4	3.1	5.9	7.2	11.7	12.7	8.6	6.3	9.3	8.1	8.8	9.3	7.9	9.0	19.8	19.4	25.6	17.3	47.3	16.6	7.9	23.3	14.3	8.6	49.8	11.6	11.0	19.5	27.1	15.6	36.8	43.8	16.2	15.0	8.5	7.9	16.4	6.0	13.6	35.3	18.5	13.1	6.7	43.4	11.1	6.8	25.8	6.6	10.8	23.5	40.8	13.6	15.6	10.3	35.3	52.9	12.4	12.2	9.1	6.1	7.9	39.7	47.7	16.0	31.9	14.6	28.5	29.9	51.8	106.7	12.3	12.0	51.1	8.7	16.9	29.2	17.1	17.6	59.3	46.0	29.7	23.3	54.4	10.8	7.9	8.7	10.1	13.6	31.0	18.9	12.2
MSH2	"COCA1, HNPCC, HNPCC1"	ENSG00000095002	"MutS homolog 2"	P43246	2	47403067-47663146	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Cancer enhanced"	"Detected in all"		"testis cancer: 46.2"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009572, HPA066845, CAB070867"	Approved		Supported	Nucleoplasm,Vesicles		NA	Yes		28000	"Cluster 48: NK-cells - Unknown function"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	Vesicles	"CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752"	"unprognostic (2.35e-1)"	"unprognostic (1.54e-2)"	"unprognostic (2.89e-3)"	"prognostic unfavorable (4.44e-4)"	"unprognostic (2.23e-1)"	"unprognostic (6.31e-3)"	"prognostic unfavorable (1.72e-9)"	"unprognostic (1.77e-1)"	"unprognostic (7.09e-3)"	"unprognostic (8.57e-2)"	"prognostic unfavorable (4.63e-4)"	"unprognostic (5.38e-2)"	"unprognostic (3.29e-3)"	"unprognostic (1.20e-3)"	"unprognostic (5.74e-1)"	"unprognostic (8.46e-2)"	"unprognostic (1.48e-1)"	8.1	7.5	8.3	12.8	10.5	15.7	15.7	14.6	10.6	9.7	12.2	11.9	7.8	11.7	14.0	9.5	12.4	5.8	10.1	9.6	9.0	8.2	6.7	8.1	23.7	8.6	8.0	8.7	6.5	14.8	6.2	11.6	9.5	8.6	15.0	34.9	8.5	7.7	7.1	11.1	9.3	8.8	8.5	10.8	8.1	16.2	7.9	32.6	15.8	7.2	25.0	7.9	6.4	8.9	114.3	35.3	103.3	57.9	7.3	21.2	64.3	62.9	33.3	80.9	76.9	72.3	50.1	141.2	84.6	23.8	56.6	49.8	78.6	37.4	122.3	68.1	55.8	99.3	42.3	65.6	7.7	97.7	34.9	12.3	11.2	68.1	19.0	19.1	45.2	3.9	165.1	34.0	63.1	44.2	119.6	75.4	195.7	69.3	45.1	151.1	182.2	84.4	35.8	57.3	85.9	91.6	58.4	49.2	48.0	83.6	46.9	38.8	18.7	55.5	70.9	57.1	74.6	20.8	63.4	180.1	33.1	72.5	35.4	3.0	1.3	4.9	8.0	4.4	9.3	6.7	7.7	10.3	2.5	7.9	12.6	13.1	1.0	14.2	3.9	3.4	11.8	6.5	8.3	10.5	14.6	10.6	9.6	9.0	8.6	8.0	9.5	8.5	7.9	8.9	14.7	9.6	11.5	18.6	13.0	8.3	7.9	14.4	8.6	17.4	7.5	7.1	15.6	5.7	12.6	9.2	45.9	19.9	14.2	6.6	3.9	11.5	17.8	21.0	11.3	13.4	3.5	54.1	59.9	8.4	20.7	12.2	7.1	18.8	12.0	28.2	5.0	1.6	11.4	11.8	58.0	12.1	14.2	4.1	4.6	22.8	5.3	5.1	8.8	16.9	5.5	22.6	17.5	35.7	54.7	7.3	5.0	6.4	12.4	2.8	5.4	4.5	23.3	41.1	0.0	9.8	9.0	56.5	50.8	9.3	6.5	5.1	12.8	24.3	13.5	3.8
MSH6	GTBP	ENSG00000116062	"MutS homolog 6"	P52701	2	47695530-47810063	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Host-virus interaction"	DNA-binding	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Granulosa cells: 119.6;Theca cells: 114.9"	"Cancer enhanced"	"Detected in all"		"testis cancer: 31.8"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009091, HPA028376, HPA028446, CAB070870"	Enhanced		Supported	"Nucleoplasm,Golgi apparatus,Vesicles"		NA	Yes		15000	"Cluster 44: Non-specific - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 40: Granulosa cells - Unknown function"	Nucleoplasm	"Golgi apparatus, Vesicles"	"CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182"	"unprognostic (5.10e-2)"	"unprognostic (5.87e-3)"	"unprognostic (3.29e-2)"	"prognostic unfavorable (1.34e-4)"	"unprognostic (1.98e-1)"	"unprognostic (3.09e-2)"	"prognostic unfavorable (7.86e-4)"	"unprognostic (1.79e-1)"	"unprognostic (2.35e-3)"	"unprognostic (1.01e-1)"	"unprognostic (1.74e-3)"	"unprognostic (8.99e-2)"	"prognostic unfavorable (1.06e-7)"	"unprognostic (1.22e-1)"	"unprognostic (2.31e-1)"	"unprognostic (9.68e-2)"	"unprognostic (3.48e-2)"	11.7	22.7	9.3	17.7	13.7	24.0	16.2	15.0	12.7	15.5	12.7	13.0	9.0	27.7	10.2	11.7	17.8	10.9	9.3	8.9	11.5	12.1	19.8	11.6	28.4	12.7	11.7	53.0	31.3	17.0	9.8	20.3	13.0	15.0	12.4	21.6	10.8	15.6	10.5	13.1	9.8	27.2	10.7	12.7	10.9	35.3	11.3	36.3	17.2	11.2	31.0	12.8	12.2	19.9	116.5	77.6	128.4	37.5	42.3	46.3	67.9	63.6	51.1	60.2	59.8	67.2	41.4	158.1	84.5	59.5	82.0	46.0	130.3	74.3	82.1	80.7	69.0	117.0	60.8	71.1	28.8	131.5	37.8	38.6	28.3	60.7	41.6	53.8	40.8	5.3	115.9	69.8	61.8	85.5	144.2	80.1	130.7	81.3	37.7	219.6	204.3	84.7	44.5	76.2	92.8	100.3	79.1	40.4	42.7	124.3	54.6	42.6	33.4	72.2	92.3	54.6	80.6	63.8	79.3	276.2	61.9	77.9	42.4	7.7	3.7	3.8	4.8	6.2	5.5	4.3	5.5	5.0	5.5	4.2	8.4	4.5	2.5	5.9	6.4	2.7	5.3	3.6	9.3	13.7	15.0	12.7	8.9	11.5	12.7	11.7	13.0	10.7	11.3	19.9	19.8	28.9	21.4	5.9	19.2	25.2	22.0	12.3	31.9	25.4	14.4	15.1	8.6	2.8	21.8	7.3	35.5	35.6	20.7	7.4	3.9	15.7	46.4	27.1	31.1	18.4	4.8	47.1	8.5	9.6	21.8	24.0	8.6	31.7	17.7	119.6	13.6	10.2	13.0	15.2	12.1	9.7	20.3	5.6	13.2	17.5	25.4	16.8	3.6	7.5	10.0	22.7	8.2	9.5	27.4	9.1	3.7	22.6	31.1	16.1	2.6	6.7	22.1	31.4	6.6	27.4	33.0	54.3	48.8	22.0	17.5	9.6	19.8	114.9	12.1	11.7
PMS2	"H_DJ0042M02.9, HNPCC4, MLH4, PMSL2"	ENSG00000122512	"PMS1 homolog 2, mismatch repair system component"	P54278	7	5970925-6009106	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010235, HPA066490, HPA070310"	Approved		Enhanced	Nucleoplasm		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 34: Non-specific - Transcription"	"Cluster 23: AN3-CA - Transcription regulation"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Nucleoplasm		"CAB010235: AB_2167281, HPA066490: AB_2685677, HPA070310: AB_2686250"	"unprognostic (5.13e-2)"	"unprognostic (6.55e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.43e-3)"	"unprognostic (5.14e-2)"	"unprognostic (1.29e-1)"	"unprognostic (7.36e-2)"	"unprognostic (1.02e-1)"	"unprognostic (7.43e-2)"	"unprognostic (2.35e-1)"	"unprognostic (1.86e-1)"	"unprognostic (7.38e-2)"	"prognostic favorable (1.23e-5)"	"unprognostic (5.31e-2)"	"unprognostic (2.01e-2)"	"unprognostic (3.67e-2)"	"unprognostic (2.81e-2)"	5.3	5.1	6.7	5.3	7.2	5.8	6.5	6.3	7.6	4.8	2.8	4.8	5.7	4.9	5.0	5.3	5.7	4.0	4.1	7.4	5.8	10.4	4.7	4.4	8.4	5.3	5.6	5.7	3.9	11.0	4.6	4.8	5.5	5.2	4.7	8.4	5.7	5.5	4.5	11.9	5.3	5.3	4.4	5.9	5.0	4.0	5.2	8.8	9.2	3.5	8.9	5.1	4.9	7.0	15.1	16.7	12.9	32.2	9.0	13.6	10.9	7.8	5.8	6.6	5.6	14.0	9.9	28.2	8.7	10.9	17.2	19.6	19.2	6.6	8.0	11.3	7.2	12.0	12.5	10.1	15.9	15.8	9.4	15.1	14.8	5.4	22.3	11.4	13.7	15.2	22.9	12.6	11.9	15.5	5.2	17.1	13.3	7.6	9.6	16.3	15.3	14.0	16.4	11.0	11.9	25.7	13.3	23.0	16.2	18.0	27.1	11.8	12.4	9.3	21.2	14.2	14.6	19.8	32.8	27.5	7.2	15.3	22.9	5.0	2.9	1.9	4.5	4.1	4.9	3.4	3.5	3.8	3.0	3.4	4.4	3.4	1.4	2.3	1.8	3.1	3.4	3.4	6.7	7.2	6.3	7.6	7.4	5.8	5.3	5.6	5.5	4.4	5.2	7.0	12.2	12.8	8.2	11.4	13.6	5.0	9.3	10.9	15.9	13.2	10.7	11.3	3.2	12.8	9.7	11.0	22.9	9.4	15.2	1.8	35.2	5.5	9.9	11.0	14.6	10.1	5.4	8.4	14.0	3.3	6.3	6.6	8.2	11.8	5.1	11.4	7.9	7.6	5.2	30.3	12.2	2.2	10.2	7.1	5.9	6.6	12.8	6.3	7.2	5.6	8.7	7.8	20.6	3.5	8.3	4.7	2.6	10.1	9.6	12.6	2.2	39.5	9.3	14.3	26.3	10.0	8.0	34.5	11.7	10.5	8.1	12.7	11.4	11.9	2.6	11.1
PRKAR1A	"CNC1, PRKAR1, TSE1"	ENSG00000108946	"Protein kinase cAMP-dependent type I regulatory subunit alpha"	P10644	17	68511780-68551319	"Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Cushing syndrome, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 606.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB019378, HPA049979"	Approved		Approved	Cytosol		NA	NA		1800000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 54: Cardiomyocytes - Muscle contraction"	Cytosol		"CAB019378: , HPA049979: AB_2680980"	"unprognostic (8.69e-2)"	"unprognostic (6.97e-2)"	"unprognostic (5.34e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.68e-1)"	"unprognostic (4.39e-2)"	"unprognostic (2.61e-1)"	"unprognostic (6.42e-2)"	"unprognostic (2.27e-1)"	"unprognostic (2.30e-1)"	"unprognostic (1.19e-2)"	"unprognostic (5.55e-2)"	"unprognostic (8.56e-3)"	"unprognostic (6.26e-2)"	"unprognostic (6.92e-2)"	"unprognostic (3.29e-2)"	"unprognostic (1.11e-1)"	125.9	158.2	72.0	124.1	83.2	57.1	118.4	76.7	119.1	151.2	97.3	70.0	51.7	145.5	122.3	98.5	141.3	125.2	430.0	89.0	102.1	164.3	150.8	163.7	111.4	85.6	91.8	202.8	63.1	300.2	88.0	164.3	105.0	114.5	79.1	132.2	169.7	137.6	250.6	63.8	58.7	132.1	71.7	121.7	86.9	130.8	91.8	109.4	173.6	147.4	103.6	136.4	67.6	93.5	95.5	180.0	225.9	136.1	294.6	331.7	33.9	125.7	257.9	192.2	168.6	70.5	125.5	96.3	84.3	276.7	196.8	77.2	168.8	204.2	273.8	65.8	60.4	149.1	154.0	233.0	213.0	115.8	160.2	239.1	207.4	222.3	185.9	215.0	324.6	80.8	68.5	147.2	236.4	181.0	128.2	60.9	83.9	97.7	121.4	88.1	373.6	106.7	292.4	204.3	81.8	110.3	115.4	207.6	496.8	208.5	162.8	161.1	232.2	269.4	127.6	123.3	119.0	121.6	93.5	142.4	163.0	107.8	171.8	149.6	108.3	189.4	48.6	101.0	48.8	42.8	35.9	43.6	105.9	32.3	32.1	35.9	208.2	76.1	120.9	34.7	50.9	113.5	72.0	83.2	76.7	119.1	89.0	102.1	85.6	91.8	105.0	71.7	91.8	93.5	134.1	147.4	263.4	38.5	126.0	142.8	100.1	136.8	116.7	99.6	106.8	65.4	606.2	81.5	156.4	252.0	66.7	77.4	127.4	58.1	178.1	80.7	407.9	142.9	116.4	131.8	136.9	52.5	76.1	52.0	86.8	163.2	78.5	110.3	185.0	78.2	158.1	120.7	146.1	139.7	78.4	53.3	136.3	176.2	171.1	93.7	133.6	151.1	192.1	46.9	142.3	125.1	78.2	57.3	76.3	74.6	51.5	190.7	95.6	85.3	27.1	210.1	307.7	59.9	85.5	123.2	210.9	219.8	54.2	122.4	131.7	82.5	117.3	184.0	43.9	112.8
SLC29A3	"ENT3, FLJ11160"	ENSG00000198246	"Solute carrier family 29 member 3"	Q9BZD2	10	71319259-71381423	"Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters"	Transport		"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 46.1;Extravillous trophoblasts: 45.3;Hofbauer cells: 34.7;Syncytiotrophoblasts: 31.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"BEWO: 31.8;Hep G2: 35.9;RT4: 29.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA046085, HPA054976, HPA057905"	Approved		Enhanced	"Golgi apparatus,Vesicles"		NA	NA			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 47: Cytotrophoblasts - Unknown function"	"Golgi apparatus, Vesicles"		"HPA046085: AB_2679531, HPA054976: AB_2682659, HPA057905: AB_2683550"	"unprognostic (1.73e-1)"	"unprognostic (2.38e-3)"	"unprognostic (3.23e-3)"	"unprognostic (1.07e-1)"	"unprognostic (3.06e-2)"	"unprognostic (1.73e-2)"	"prognostic unfavorable (6.07e-6)"	"unprognostic (1.28e-1)"	"unprognostic (4.71e-1)"	"unprognostic (1.81e-1)"	"unprognostic (2.53e-1)"	"unprognostic (3.80e-2)"	"prognostic unfavorable (5.53e-5)"	"unprognostic (3.37e-1)"	"unprognostic (1.36e-1)"	"prognostic favorable (1.16e-4)"	"unprognostic (3.43e-3)"	4.7	2.6	3.1	4.1	3.9	1.1	4.8	3.7	3.7	7.3	2.7	4.4	2.1	6.8	2.5	2.2	5.8	4.4	2.4	3.0	3.6	2.5	9.4	6.7	7.1	4.7	3.7	9.7	5.2	3.5	1.7	11.2	4.2	5.1	3.5	0.3	4.9	2.9	1.4	2.6	3.7	5.1	4.2	6.5	6.1	3.7	4.4	3.7	3.8	0.6	3.8	9.8	4.4	5.0	2.1	12.3	1.8	7.8	6.8	5.3	31.8	2.3	2.2	0.7	0.4	13.8	8.8	7.4	6.4	4.7	3.2	18.3	5.7	2.9	0.1	5.6	5.6	2.2	1.0	35.9	3.3	1.8	4.5	5.2	12.9	0.3	0.6	1.5	3.2	8.5	6.5	6.8	0.9	19.1	4.2	3.8	4.2	19.2	4.5	5.7	0.6	5.9	2.3	29.5	8.5	9.6	6.4	20.3	1.7	5.2	3.2	4.0	5.2	0.2	3.8	2.3	0.1	1.8	3.1	4.0	7.6	24.0	1.3	4.2	19.3	2.2	5.4	15.3	4.6	4.9	4.5	5.1	29.1	1.9	3.5	5.0	1.5	9.4	10.3	20.2	5.5	9.5	3.1	3.9	3.7	3.7	3.0	3.6	4.7	3.7	4.2	4.2	4.4	5.0	2.0	3.2	1.1	2.0	3.1	0.3	1.5	4.0	1.8	2.3	2.7	3.8	0.8	1.5	3.8	0.0	0.0	46.1	6.3	2.6	0.0	6.1	3.6	1.8	3.2	1.8	1.8	4.2	2.4	8.9	45.3	4.7	7.1	2.4	2.5	10.2	3.3	5.4	34.7	0.0	1.3	2.5	8.2	11.8	4.4	15.2	2.8	10.9	1.8	16.9	8.5	3.0	3.1	2.5	2.7	7.9	13.1	1.5	6.0	3.2	0.1	2.0	2.6	0.4	0.0	0.2	2.5	0.6	5.0	0.7	0.0	31.7	2.9	10.0	2.5	1.7
SMARCA4	"BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2"	ENSG00000127616	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4"	P51532	19	10960932-11079426	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Neurogenesis, Transcription, Transcription regulation"	"Activator, Chromatin regulator, Helicase, Hydrolase, Repressor, RNA-binding"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 372.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004208, HPA048340"	Supported		Supported	"Nucleoplasm,Nucleoli fibrillar center,Nucleoli rim"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 14: REH - Unknown function"	"Cluster 43: Cardiomyocytes - Nuclear processes"	Nucleoplasm	"Nucleoli fibrillar center, Nucleoli rim"	"CAB004208: AB_626762, HPA048340: "	"unprognostic (2.68e-1)"	"unprognostic (4.85e-2)"	"unprognostic (1.71e-1)"	"unprognostic (3.43e-3)"	"unprognostic (1.40e-1)"	"unprognostic (6.33e-3)"	"prognostic unfavorable (1.11e-4)"	"unprognostic (7.19e-2)"	"unprognostic (7.29e-2)"	"unprognostic (1.73e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.15e-2)"	"unprognostic (6.80e-3)"	"unprognostic (6.83e-3)"	"unprognostic (5.44e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.29e-1)"	13.8	16.2	14.4	22.6	14.3	31.8	13.0	15.3	23.7	16.1	13.2	18.1	19.9	14.5	9.5	32.9	20.8	13.3	16.2	15.4	9.6	15.7	8.6	17.9	27.0	10.4	10.4	14.9	18.3	22.9	11.1	20.2	11.0	17.7	12.9	19.7	25.9	15.6	23.7	28.1	17.2	14.5	3.9	19.5	20.4	30.2	11.8	43.1	20.6	13.9	23.7	17.4	14.7	19.3	92.5	5.0	157.2	149.8	30.3	25.4	68.9	62.7	37.2	74.6	54.9	126.9	4.0	215.4	94.2	54.9	3.0	65.9	123.6	77.5	40.8	89.5	93.3	171.3	76.5	149.6	45.7	125.5	82.0	43.1	36.7	63.1	64.5	33.3	67.5	92.0	156.7	78.3	59.2	188.0	210.0	107.5	159.9	45.1	134.7	220.6	99.5	111.7	47.9	114.8	177.8	161.7	66.6	84.4	73.5	50.1	71.9	93.3	90.9	110.3	57.3	102.5	104.9	160.6	192.2	209.1	62.6	118.5	96.0	5.7	5.8	6.4	9.3	6.9	8.2	5.3	6.8	7.9	6.1	6.8	7.6	7.5	3.4	8.5	10.8	7.9	6.4	4.7	14.4	14.3	15.3	23.7	15.4	9.6	10.4	10.4	11.0	3.9	11.8	19.3	25.4	67.3	72.6	27.4	28.5	37.0	43.7	43.8	24.5	91.3	42.2	28.4	372.9	40.0	62.7	44.1	70.9	65.9	21.2	60.1	41.1	79.8	53.0	58.8	49.2	58.3	63.2	41.8	32.2	61.4	57.3	43.8	50.0	63.5	30.4	75.3	28.5	21.9	42.3	101.0	39.6	47.7	57.0	23.8	21.5	37.6	26.1	30.4	16.0	14.0	43.8	36.1	23.7	32.6	28.1	76.4	41.8	13.5	37.6	66.0	29.8	27.6	62.5	69.1	13.1	45.1	66.4	99.4	86.0	52.2	51.7	61.0	30.4	68.1	60.5	50.1
SMARCB1	"BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1"	ENSG00000099956	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1"	Q12824	22	23786931-23838009	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation"	"Activator, Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease variant, Hypotrichosis, Mental retardation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009196, HPA018248, HPA019127"	Supported		Supported	"Nucleoplasm,Nucleoli fibrillar center"		NA	NA			"Cluster 43: B-cells - Humoral immune response"	"Cluster 72: Non-specific - Transcription"	"Cluster 12: NES - Nervous system development"	"Cluster 57: B-cells - Immune response"	Nucleoplasm	"Nucleoli fibrillar center"	"CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165"	"unprognostic (2.15e-1)"	"unprognostic (5.62e-2)"	"unprognostic (6.60e-3)"	"unprognostic (1.63e-2)"	"unprognostic (4.01e-3)"	"unprognostic (2.14e-1)"	"prognostic unfavorable (6.52e-4)"	"unprognostic (4.10e-1)"	"unprognostic (1.86e-1)"	"unprognostic (1.03e-2)"	"unprognostic (2.10e-2)"	"unprognostic (4.43e-3)"	"prognostic favorable (1.14e-6)"	"unprognostic (1.24e-1)"	"unprognostic (4.58e-2)"	"unprognostic (4.57e-2)"	"unprognostic (7.04e-2)"	35.9	46.4	2.3	6.9	2.5	3.3	40.3	4.1	10.0	51.5	2.7	40.9	8.1	51.4	0.4	51.0	40.4	2.2	44.0	2.3	2.3	47.0	36.9	32.3	5.8	4.3	2.7	63.1	43.9	1.2	48.0	1.2	2.7	36.6	1.1	25.3	44.1	0.6	48.1	50.1	51.7	0.6	2.2	51.7	40.4	68.3	2.3	3.5	41.3	1.8	1.5	37.5	40.9	2.9	2.4	1.6	28.2	2.6	2.7	0.7	5.8	9.2	2.7	2.7	4.3	3.4	2.6	24.2	7.9	1.2	2.9	4.4	6.9	4.6	4.5	4.1	10.5	20.1	3.2	2.1	3.0	21.7	5.6	1.6	3.4	3.2	6.9	1.4	1.4	3.0	5.6	12.9	1.7	6.1	17.6	5.0	8.6	7.2	5.7	11.0	23.1	10.8	2.3	4.5	13.4	10.1	2.2	0.6	17.9	14.8	2.2	3.3	2.2	2.4	9.8	3.8	2.7	13.8	14.3	17.7	1.8	11.3	6.8	7.1	12.8	6.4	4.4	13.4	6.4	24.4	5.5	5.7	12.0	9.2	4.5	3.0	1.1	9.8	16.8	13.3	10.4	8.1	2.3	2.5	4.1	10.0	2.3	2.3	4.3	2.7	2.7	2.2	2.3	2.9	33.6	6.4	8.6	17.0	120.2	50.2	73.3	85.1	51.2	55.4	42.9	49.1	6.1	47.1	37.4	47.8	20.9	120.6	61.8	36.6	84.1	94.6	42.6	40.9	54.9	37.4	71.8	57.8	14.1	77.1	228.1	46.2	41.8	41.1	34.8	112.2	41.0	20.3	76.1	67.3	18.4	54.6	99.7	23.0	41.7	18.9	35.8	36.5	56.9	15.9	51.2	92.4	45.3	17.1	18.1	74.7	53.1	32.0	139.6	74.4	41.9	86.4	28.5	49.6	19.7	47.7	62.8	138.9	163.3	64.5	53.0	160.1	42.0	96.8	65.4	65.1
TP53	"LFS1, p53"	ENSG00000141510	"Tumor protein p53"	P04637	17	7661779-7687538	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters"	"Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876, CAB079965"	Enhanced		Supported	Nucleoplasm,Mitochondria,Cytosol		Yes	No			"Cluster 39: Non-specific - mRNA processing"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 14: REH - Unknown function"	"Cluster 32: Non-specific - Translation"	Nucleoplasm	"Mitochondria, Cytosol"	"CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, CAB079965: , HPA051244: AB_2681403, HPA063532: "	"unprognostic (2.29e-2)"	"unprognostic (8.83e-3)"	"unprognostic (1.26e-2)"	"prognostic favorable (1.35e-4)"	"unprognostic (9.95e-2)"	"unprognostic (4.00e-2)"	"unprognostic (2.79e-3)"	"unprognostic (4.99e-2)"	"unprognostic (2.75e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.30e-1)"	"prognostic unfavorable (5.01e-4)"	"unprognostic (1.86e-3)"	"unprognostic (7.89e-3)"	"unprognostic (8.05e-2)"	"unprognostic (2.74e-1)"	"unprognostic (1.08e-1)"	19.3	13.8	10.4	27.1	12.6	19.6	22.5	10.4	16.5	19.9	10.3	29.0	18.9	24.5	12.8	28.8	31.3	13.2	11.1	10.1	11.4	14.9	16.5	15.1	34.6	18.7	13.6	27.3	18.3	9.4	7.3	23.5	12.5	17.7	27.5	4.1	18.9	15.3	12.3	37.4	20.4	24.6	12.6	31.1	22.6	10.4	12.3	47.2	17.4	6.1	45.4	20.8	19.9	13.3	81.5	145.3	81.1	57.3	37.3	43.9	82.8	28.4	66.1	78.5	100.2	4.2	40.6	190.5	126.9	58.7	77.6	174.9	119.7	80.4	72.8	42.7	76.5	77.6	76.8	70.9	111.5	1.6	37.0	55.7	93.0	38.9	106.5	45.6	79.4	24.7	3.8	6.9	41.5	145.1	130.0	96.3	80.2	10.4	2.4	252.2	56.1	66.2	59.4	87.3	46.0	80.5	94.1	62.6	24.3	39.4	109.2	7.4	100.7	91.6	30.2	1.0	48.3	47.6	37.9	82.5	23.6	9.7	80.1	1.2	21.2	3.4	13.0	21.7	15.9	21.5	13.3	14.6	30.3	19.1	13.7	15.4	2.4	17.5	19.3	27.3	17.3	14.7	10.4	12.6	10.4	16.5	10.1	11.4	18.7	13.6	12.5	12.6	12.3	13.3	21.1	9.6	12.8	16.3	26.0	28.7	14.5	24.6	24.5	2.6	36.1	30.4	2.5	18.6	15.4	20.2	0.0	36.9	24.7	16.9	9.8	24.8	12.8	11.5	29.0	24.5	30.7	21.7	2.1	18.1	39.6	17.0	11.2	19.5	1.3	31.7	22.1	18.0	24.2	0.0	3.2	43.0	18.3	27.8	20.1	3.8	23.0	19.3	12.4	7.5	31.9	4.9	25.7	9.0	8.0	15.8	16.4	17.0	7.8	15.7	10.3	10.1	8.8	2.6	13.1	25.9	20.6	0.5	4.9	28.7	32.8	22.4	16.5	27.4	54.1	11.5