Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [nTPM]"	"Tissue RNA - adrenal gland [nTPM]"	"Tissue RNA - amygdala [nTPM]"	"Tissue RNA - appendix [nTPM]"	"Tissue RNA - basal ganglia [nTPM]"	"Tissue RNA - bone marrow [nTPM]"	"Tissue RNA - breast [nTPM]"	"Tissue RNA - cerebellum [nTPM]"	"Tissue RNA - cerebral cortex [nTPM]"	"Tissue RNA - cervix [nTPM]"	"Tissue RNA - choroid plexus [nTPM]"	"Tissue RNA - colon [nTPM]"	"Tissue RNA - duodenum [nTPM]"	"Tissue RNA - endometrium 1 [nTPM]"	"Tissue RNA - epididymis [nTPM]"	"Tissue RNA - esophagus [nTPM]"	"Tissue RNA - fallopian tube [nTPM]"	"Tissue RNA - gallbladder [nTPM]"	"Tissue RNA - heart muscle [nTPM]"	"Tissue RNA - hippocampal formation [nTPM]"	"Tissue RNA - hypothalamus [nTPM]"	"Tissue RNA - kidney [nTPM]"	"Tissue RNA - liver [nTPM]"	"Tissue RNA - lung [nTPM]"	"Tissue RNA - lymph node [nTPM]"	"Tissue RNA - medulla oblongata [nTPM]"	"Tissue RNA - midbrain [nTPM]"	"Tissue RNA - ovary [nTPM]"	"Tissue RNA - pancreas [nTPM]"	"Tissue RNA - parathyroid gland [nTPM]"	"Tissue RNA - pituitary gland [nTPM]"	"Tissue RNA - placenta [nTPM]"	"Tissue RNA - pons [nTPM]"	"Tissue RNA - prostate [nTPM]"	"Tissue RNA - rectum [nTPM]"	"Tissue RNA - retina [nTPM]"	"Tissue RNA - salivary gland [nTPM]"	"Tissue RNA - seminal vesicle [nTPM]"	"Tissue RNA - skeletal muscle [nTPM]"	"Tissue RNA - skin 1 [nTPM]"	"Tissue RNA - small intestine [nTPM]"	"Tissue RNA - smooth muscle [nTPM]"	"Tissue RNA - spinal cord [nTPM]"	"Tissue RNA - spleen [nTPM]"	"Tissue RNA - stomach 1 [nTPM]"	"Tissue RNA - testis [nTPM]"	"Tissue RNA - thalamus [nTPM]"	"Tissue RNA - thymus [nTPM]"	"Tissue RNA - thyroid gland [nTPM]"	"Tissue RNA - tongue [nTPM]"	"Tissue RNA - tonsil [nTPM]"	"Tissue RNA - urinary bladder [nTPM]"	"Tissue RNA - vagina [nTPM]"	"Tissue RNA - white matter [nTPM]"	"Cell RNA - A-431 [nTPM]"	"Cell RNA - A549 [nTPM]"	"Cell RNA - AF22 [nTPM]"	"Cell RNA - AN3-CA [nTPM]"	"Cell RNA - ASC diff [nTPM]"	"Cell RNA - ASC TERT1 [nTPM]"	"Cell RNA - BEWO [nTPM]"	"Cell RNA - BJ [nTPM]"	"Cell RNA - BJ hTERT+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]"	"Cell RNA - CACO-2 [nTPM]"	"Cell RNA - CAPAN-2 [nTPM]"	"Cell RNA - Daudi [nTPM]"	"Cell RNA - EFO-21 [nTPM]"	"Cell RNA - fHDF/TERT166 [nTPM]"	"Cell RNA - GAMG [nTPM]"	"Cell RNA - HaCaT [nTPM]"	"Cell RNA - HAP1 [nTPM]"	"Cell RNA - HBEC3-KT [nTPM]"	"Cell RNA - HBF TERT88 [nTPM]"	"Cell RNA - HDLM-2 [nTPM]"	"Cell RNA - HEK 293 [nTPM]"	"Cell RNA - HEL [nTPM]"	"Cell RNA - HeLa [nTPM]"	"Cell RNA - Hep G2 [nTPM]"	"Cell RNA - HHSteC [nTPM]"	"Cell RNA - HL-60 [nTPM]"	"Cell RNA - HMC-1 [nTPM]"	"Cell RNA - HSkMC [nTPM]"	"Cell RNA - hTCEpi [nTPM]"	"Cell RNA - hTEC/SVTERT24-B [nTPM]"	"Cell RNA - hTERT-HME1 [nTPM]"	"Cell RNA - hTERT-RPE1 [nTPM]"	"Cell RNA - HUVEC TERT2 [nTPM]"	"Cell RNA - JURKAT [nTPM]"	"Cell RNA - K-562 [nTPM]"	"Cell RNA - Karpas-707 [nTPM]"	"Cell RNA - LHCN-M2 [nTPM]"	"Cell RNA - MCF7 [nTPM]"	"Cell RNA - MOLT-4 [nTPM]"	"Cell RNA - NB-4 [nTPM]"	"Cell RNA - NTERA-2 [nTPM]"	"Cell RNA - OE19 [nTPM]"	"Cell RNA - PC-3 [nTPM]"	"Cell RNA - REH [nTPM]"	"Cell RNA - RH-30 [nTPM]"	"Cell RNA - RPMI-8226 [nTPM]"	"Cell RNA - RPTEC TERT1 [nTPM]"	"Cell RNA - RT4 [nTPM]"	"Cell RNA - SCLC-21H [nTPM]"	"Cell RNA - SH-SY5Y [nTPM]"	"Cell RNA - SiHa [nTPM]"	"Cell RNA - SK-BR-3 [nTPM]"	"Cell RNA - SK-MEL-30 [nTPM]"	"Cell RNA - SuSa [nTPM]"	"Cell RNA - T-47d [nTPM]"	"Cell RNA - THP-1 [nTPM]"	"Cell RNA - TIME [nTPM]"	"Cell RNA - U-138 MG [nTPM]"	"Cell RNA - U-2 OS [nTPM]"	"Cell RNA - U-2197 [nTPM]"	"Cell RNA - U-251 MG [nTPM]"	"Cell RNA - U-266/70 [nTPM]"	"Cell RNA - U-266/84 [nTPM]"	"Cell RNA - U-698 [nTPM]"	"Cell RNA - U-87 MG [nTPM]"	"Cell RNA - U-937 [nTPM]"	"Cell RNA - WM-115 [nTPM]"	"Blood RNA - basophil [nTPM]"	"Blood RNA - classical monocyte [nTPM]"	"Blood RNA - eosinophil [nTPM]"	"Blood RNA - gdT-cell [nTPM]"	"Blood RNA - intermediate monocyte [nTPM]"	"Blood RNA - MAIT T-cell [nTPM]"	"Blood RNA - memory B-cell [nTPM]"	"Blood RNA - memory CD4 T-cell [nTPM]"	"Blood RNA - memory CD8 T-cell [nTPM]"	"Blood RNA - myeloid DC [nTPM]"	"Blood RNA - naive B-cell [nTPM]"	"Blood RNA - naive CD4 T-cell [nTPM]"	"Blood RNA - naive CD8 T-cell [nTPM]"	"Blood RNA - neutrophil [nTPM]"	"Blood RNA - NK-cell [nTPM]"	"Blood RNA - non-classical monocyte [nTPM]"	"Blood RNA - plasmacytoid DC [nTPM]"	"Blood RNA - T-reg [nTPM]"	"Blood RNA - total PBMC [nTPM]"	"Brain RNA - amygdala [nTPM]"	"Brain RNA - basal ganglia [nTPM]"	"Brain RNA - cerebellum [nTPM]"	"Brain RNA - cerebral cortex [nTPM]"	"Brain RNA - hippocampal formation [nTPM]"	"Brain RNA - hypothalamus [nTPM]"	"Brain RNA - medulla oblongata [nTPM]"	"Brain RNA - midbrain [nTPM]"	"Brain RNA - pons [nTPM]"	"Brain RNA - spinal cord [nTPM]"	"Brain RNA - thalamus [nTPM]"	"Brain RNA - white matter [nTPM]"	"Single Cell Type RNA - Adipocytes [nTPM]"	"Single Cell Type RNA - Alveolar cells type 1 [nTPM]"	"Single Cell Type RNA - Alveolar cells type 2 [nTPM]"	"Single Cell Type RNA - Astrocytes [nTPM]"	"Single Cell Type RNA - B-cells [nTPM]"	"Single Cell Type RNA - Basal keratinocytes [nTPM]"	"Single Cell Type RNA - Basal prostatic cells [nTPM]"	"Single Cell Type RNA - Basal respiratory cells [nTPM]"	"Single Cell Type RNA - Basal squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Bipolar cells [nTPM]"	"Single Cell Type RNA - Breast glandular cells [nTPM]"	"Single Cell Type RNA - Breast myoepithelial cells [nTPM]"	"Single Cell Type RNA - Cardiomyocytes [nTPM]"	"Single Cell Type RNA - Cholangiocytes [nTPM]"	"Single Cell Type RNA - Club cells [nTPM]"	"Single Cell Type RNA - Collecting duct cells [nTPM]"	"Single Cell Type RNA - Cone photoreceptor cells [nTPM]"	"Single Cell Type RNA - Cytotrophoblasts [nTPM]"	"Single Cell Type RNA - dendritic cells [nTPM]"	"Single Cell Type RNA - Distal enterocytes [nTPM]"	"Single Cell Type RNA - Distal tubular cells [nTPM]"	"Single Cell Type RNA - Ductal cells [nTPM]"	"Single Cell Type RNA - Early spermatids [nTPM]"	"Single Cell Type RNA - Endometrial ciliated cells [nTPM]"	"Single Cell Type RNA - Endometrial stromal cells [nTPM]"	"Single Cell Type RNA - Endothelial cells [nTPM]"	"Single Cell Type RNA - Enteroendocrine cells [nTPM]"	"Single Cell Type RNA - Erythroid cells [nTPM]"	"Single Cell Type RNA - Excitatory neurons [nTPM]"	"Single Cell Type RNA - Exocrine glandular cells [nTPM]"	"Single Cell Type RNA - Extravillous trophoblasts [nTPM]"	"Single Cell Type RNA - Fibroblasts [nTPM]"	"Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]"	"Single Cell Type RNA - Glandular and luminal cells [nTPM]"	"Single Cell Type RNA - granulocytes [nTPM]"	"Single Cell Type RNA - Granulosa cells [nTPM]"	"Single Cell Type RNA - Hepatic stellate cells [nTPM]"	"Single Cell Type RNA - Hepatocytes [nTPM]"	"Single Cell Type RNA - Hofbauer cells [nTPM]"	"Single Cell Type RNA - Horizontal cells [nTPM]"	"Single Cell Type RNA - Inhibitory neurons [nTPM]"	"Single Cell Type RNA - Intestinal goblet cells [nTPM]"	"Single Cell Type RNA - Ionocytes [nTPM]"	"Single Cell Type RNA - Kupffer cells [nTPM]"	"Single Cell Type RNA - Langerhans cells [nTPM]"	"Single Cell Type RNA - Late spermatids [nTPM]"	"Single Cell Type RNA - Leydig cells [nTPM]"	"Single Cell Type RNA - Macrophages [nTPM]"	"Single Cell Type RNA - Melanocytes [nTPM]"	"Single Cell Type RNA - Microglial cells [nTPM]"	"Single Cell Type RNA - monocytes [nTPM]"	"Single Cell Type RNA - Muller glia cells [nTPM]"	"Single Cell Type RNA - NK-cells [nTPM]"	"Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]"	"Single Cell Type RNA - Oligodendrocytes [nTPM]"	"Single Cell Type RNA - Pancreatic endocrine cells [nTPM]"	"Single Cell Type RNA - Paneth cells [nTPM]"	"Single Cell Type RNA - Peritubular cells [nTPM]"	"Single Cell Type RNA - Plasma cells [nTPM]"	"Single Cell Type RNA - Prostatic glandular cells [nTPM]"	"Single Cell Type RNA - Proximal enterocytes [nTPM]"	"Single Cell Type RNA - Proximal tubular cells [nTPM]"	"Single Cell Type RNA - Respiratory ciliated cells [nTPM]"	"Single Cell Type RNA - Rod photoreceptor cells [nTPM]"	"Single Cell Type RNA - Sertoli cells [nTPM]"	"Single Cell Type RNA - Skeletal myocytes [nTPM]"	"Single Cell Type RNA - Smooth muscle cells [nTPM]"	"Single Cell Type RNA - Spermatocytes [nTPM]"	"Single Cell Type RNA - Spermatogonia [nTPM]"	"Single Cell Type RNA - Squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Suprabasal keratinocytes [nTPM]"	"Single Cell Type RNA - Syncytiotrophoblasts [nTPM]"	"Single Cell Type RNA - T-cells [nTPM]"	"Single Cell Type RNA - Theca cells [nTPM]"	"Single Cell Type RNA - Undifferentiated cells [nTPM]"	"Single Cell Type RNA - Urothelial cells [nTPM]"
AASS	"LKRSDH, LORSDH"	ENSG00000008311	"Aminoadipate-semialdehyde synthase"	Q9UDR5	7	122064583-122144308	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		"Multifunctional enzyme, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 44.3"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 145.9;Hepatocytes: 113.9;Oligodendrocyte precursor cells: 106.1;Oligodendrocytes: 132.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"AN3-CA: 41.5;NTERA-2: 55.3;SuSa: 37.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA020637, HPA020728, HPA020734"	Enhanced		Approved	Nucleoplasm,Vesicles,Mitochondria		Yes	No		19000		"Cluster 15: Liver - Metabolism"	"Cluster 12: NES - Nervous system development"	"Cluster 64: Astrocytes - Nervous system maintenance"	Mitochondria	"Nucleoplasm, Vesicles"	"HPA020637: AB_1844415, HPA020728: AB_1844416, HPA020734: AB_1844417"	"unprognostic (4.84e-2)"	"unprognostic (2.29e-1)"	"unprognostic (7.91e-4)"	"unprognostic (6.08e-2)"	"unprognostic (1.49e-2)"	"unprognostic (8.00e-2)"	"prognostic favorable (9.81e-4)"	"unprognostic (4.48e-3)"	"unprognostic (2.38e-1)"	"unprognostic (1.47e-1)"	"unprognostic (1.98e-1)"	"unprognostic (1.99e-1)"	"unprognostic (7.76e-3)"	"unprognostic (8.56e-3)"	"unprognostic (1.55e-1)"	"unprognostic (6.50e-2)"	"unprognostic (2.67e-1)"	9.7	5.9	10.0	1.8	12.2	0.2	8.4	10.3	14.4	8.2	15.5	5.2	0.9	9.5	7.5	3.2	11.7	2.1	9.2	9.4	10.6	13.9	44.3	6.3	1.4	11.6	11.0	25.2	4.8	7.1	3.5	3.2	11.4	5.4	1.4	3.7	3.5	4.8	8.6	2.8	3.6	4.4	10.1	2.9	5.5	2.2	11.0	1.5	4.7	6.2	1.4	6.9	6.2	11.8	0.1	0.0	21.9	41.5	27.3	13.5	9.4	5.4	8.0	7.3	9.1	12.6	0.1	0.0	0.2	6.6	8.3	4.1	33.5	16.8	9.6	0.0	12.2	9.4	4.3	12.5	22.0	0.0	2.9	12.2	0.5	9.2	7.1	18.9	19.8	12.1	2.7	15.5	5.1	0.1	0.9	0.0	55.3	0.1	1.7	11.8	16.3	0.3	5.3	2.4	2.7	0.7	1.5	0.0	5.3	37.8	0.5	0.0	8.1	13.6	3.4	7.0	8.3	3.5	3.0	0.0	4.9	0.8	5.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	10.0	12.2	10.3	14.4	9.4	10.6	11.6	11.0	11.4	10.1	11.0	11.8	16.0	9.6	37.8	145.9	2.1	6.2	9.0	2.8	14.8	7.0	8.7	6.3	9.7	14.3	5.6	14.7	16.7	11.6	1.5	0.6	0.0	2.7	12.2	4.1	24.0	11.7	3.0	5.2	5.0	1.8	3.3	14.4	5.6	7.7	3.8	18.1	24.7	113.9	1.5	11.8	4.4	2.6	2.0	2.2	2.5	7.4	19.0	1.4	12.4	35.6	0.0	8.9	0.0	106.1	132.5	2.3	2.5	24.5	1.6	4.7	5.4	8.6	0.9	3.3	19.7	38.9	15.8	12.4	2.4	7.8	4.7	5.1	2.1	8.0	1.9	4.8
ACADL	"ACAD4, LCAD"	ENSG00000115361	"Acyl-CoA dehydrogenase long chain"	P28330	2	210187126-210225447	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 28.0;pancreas: 28.4"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 70.9;Early spermatids: 85.6;Late spermatids: 69.4;Leydig cells: 46.9;Peritubular cells: 46.6;Proximal tubular cells: 31.5"	"Group enriched"	"Detected in many"	8	"liver cancer: 2.2;prostate cancer: 6.8;renal cancer: 8.8;thyroid cancer: 4.6"	"Low region specificity"	"Detected in some"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HeLa: 2.4;RPTEC TERT1: 2.6;SuSa: 2.3;U-2 OS: 1.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA011990	Enhanced	Supported				NA	NA				"Cluster 29: Non-specific - Vesicular transport"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 10: Non-specific - Unknown function"			"HPA011990: AB_1844465"	"unprognostic (6.29e-3)"	"unprognostic (7.61e-2)"		"unprognostic (1.40e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.33e-2)"	"unprognostic (7.66e-3)"	"unprognostic (3.24e-1)"	"unprognostic (1.55e-1)"	"unprognostic (1.75e-1)"	"unprognostic (1.66e-1)"	"unprognostic (1.99e-1)"	"prognostic favorable (1.58e-11)"	"unprognostic (4.22e-3)"	"unprognostic (1.18e-4)"	"unprognostic (8.81e-3)"	"unprognostic (1.06e-1)"	11.9	1.1	0.8	0.1	0.8	0.0	8.0	0.7	1.1	3.4	0.9	0.5	0.0	0.7	1.1	0.5	4.0	0.6	3.1	0.7	1.2	19.8	28.0	10.1	0.0	0.8	0.8	12.7	28.4	4.5	2.9	1.0	0.8	20.6	0.1	0.0	6.8	4.8	9.5	2.8	0.4	0.1	0.8	0.0	5.6	3.1	0.7	1.5	23.7	5.0	0.0	1.0	3.8	0.9	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0	0.9	0.0	2.4	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.0	2.6	0.5	0.0	0.1	0.0	0.0	0.0	2.3	0.0	0.0	0.0	0.0	1.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.8	0.7	1.1	0.7	1.2	0.8	0.8	0.8	0.8	0.7	0.9	0.2	28.9	70.9	1.0	0.0	0.6	1.4	1.1	1.2	0.2	1.3	0.5	1.1	8.6	7.6	22.0	2.1	8.8	0.0	0.0	15.6	4.0	85.6	7.1	0.4	0.2	0.0	0.0	0.2	11.9	0.3	4.9	3.6	5.9	2.5	0.8	0.7	23.0	0.5	0.0	13.3	0.0	0.0	0.3	0.4	69.4	46.9	0.4	0.0	4.7	0.0	0.2	0.0	7.5	0.3	3.9	0.0	46.6	0.0	8.2	0.0	31.5	2.4	0.2	0.0	7.6	13.7	0.7	0.7	0.7	1.0	6.3	0.4	0.1	0.0	0.7
ACADM	"ACAD1, MCAD, MCADH"	ENSG00000117054	"Acyl-CoA dehydrogenase medium chain"	P11310	1	75724431-75787575	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 367.3;skeletal muscle: 380.0;tongue: 475.9"	"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 373.1;Distal tubular cells: 344.4;Hepatocytes: 261.2;Proximal tubular cells: 564.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"Daudi: 289.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006198, HPA026542"	Enhanced		Enhanced	Mitochondria		NA	NA		930000	"Cluster 19: B-cells - Humoral immune response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Mitochondria		"HPA006198: AB_1078087, HPA026542: AB_1844469"	"unprognostic (9.04e-3)"	"unprognostic (2.36e-1)"	"prognostic favorable (7.30e-4)"	"unprognostic (5.09e-3)"	"unprognostic (1.61e-3)"	"unprognostic (5.68e-2)"	"unprognostic (6.75e-2)"	"unprognostic (1.11e-1)"	"unprognostic (8.02e-2)"	"unprognostic (4.95e-2)"	"unprognostic (9.40e-3)"	"unprognostic (3.35e-1)"	"prognostic favorable (3.83e-8)"	"unprognostic (1.27e-1)"	"unprognostic (4.09e-2)"	"unprognostic (3.56e-2)"	"unprognostic (1.24e-1)"	81.9	82.2	25.2	24.3	25.0	17.3	69.9	26.6	42.2	29.3	30.4	46.8	103.9	20.0	25.3	51.3	30.6	27.8	217.8	24.3	25.9	295.9	367.3	22.6	42.6	26.9	26.8	35.7	35.9	66.3	19.2	16.9	25.8	26.8	49.5	21.2	31.4	26.2	380.0	14.4	75.6	25.5	26.2	27.4	52.8	35.7	25.8	29.7	38.4	475.9	44.3	32.7	21.3	25.2	25.8	20.5	61.0	26.8	53.1	42.1	17.5	48.1	40.4	46.1	38.5	38.3	39.5	289.1	40.7	34.4	39.0	22.8	54.9	41.8	57.8	113.0	25.5	94.4	58.5	58.3	36.4	80.0	23.9	50.7	23.5	39.8	22.8	35.0	36.2	56.6	102.3	60.4	50.5	9.6	96.3	40.6	50.2	80.4	49.5	118.8	83.8	30.6	77.9	70.7	33.8	43.0	38.0	111.6	102.0	43.1	32.7	107.6	20.2	29.9	29.6	26.6	78.1	38.6	62.0	128.1	25.8	67.0	35.3	15.3	14.2	19.3	17.1	20.9	27.3	40.7	17.8	21.5	21.4	24.6	20.3	23.6	0.5	25.0	20.4	23.2	19.5	19.5	25.2	25.0	26.6	42.2	24.3	25.9	26.9	26.8	25.8	26.2	25.8	25.2	42.9	57.7	58.3	29.7	56.5	27.3	41.8	69.0	44.3	39.0	49.0	40.9	373.1	52.9	63.0	58.8	25.0	35.8	39.4	42.6	344.4	37.9	55.4	27.1	32.2	36.2	40.7	67.6	51.6	26.5	19.5	47.6	26.0	25.4	44.9	61.5	43.9	261.2	75.7	30.3	46.7	38.7	63.1	45.6	22.2	24.4	46.9	38.2	51.6	19.7	32.8	53.7	29.9	36.2	36.0	21.2	49.7	45.5	74.9	24.2	88.0	564.8	106.7	30.0	0.0	38.6	43.7	76.3	86.1	46.6	27.0	15.3	39.4	72.5	46.7	35.9
ACADS	"ACAD3, SCAD"	ENSG00000122971	"Acyl-CoA dehydrogenase short chain"	P16219	12	120725774-120740008	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 245.5;skeletal muscle: 158.2"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 303.1;Hepatocytes: 203.3;Paneth cells: 185.7;Proximal enterocytes: 435.0;Undifferentiated cells: 185.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"HMC-1: 36.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004799, CAB019284, HPA022271"	Enhanced		Supported	Mitochondria		NA	NA			"Cluster 26: Non-specific - Mitochondria"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 45: Enterocytes - Digestion"	Mitochondria		"CAB019284: , HPA004799: AB_1844471, HPA022271: AB_1844472"	"unprognostic (7.14e-2)"	"unprognostic (3.03e-3)"	"unprognostic (8.15e-2)"	"prognostic favorable (5.05e-4)"	"unprognostic (1.11e-3)"	"unprognostic (5.75e-2)"	"prognostic favorable (2.43e-4)"	"unprognostic (5.65e-2)"	"unprognostic (1.22e-1)"	"unprognostic (2.14e-1)"	"unprognostic (2.69e-2)"	"unprognostic (4.04e-2)"	"prognostic favorable (3.33e-6)"	"unprognostic (1.23e-2)"	"unprognostic (1.81e-1)"	"unprognostic (1.21e-1)"	"prognostic favorable (6.34e-5)"	50.3	52.7	13.3	11.1	15.4	14.3	40.9	13.6	16.6	11.2	13.7	74.0	84.8	10.2	0.9	14.1	10.2	8.5	90.5	12.3	13.8	51.9	245.5	13.4	6.4	14.6	14.2	8.6	33.1	4.7	9.2	7.5	13.1	13.9	21.3	0.9	19.2	7.2	158.2	13.7	73.2	5.8	14.0	31.6	34.5	20.3	16.0	6.6	21.9	79.7	3.4	18.0	12.7	14.8	3.2	11.4	0.6	9.7	12.9	5.1	11.1	4.7	4.6	6.0	4.5	8.9	8.0	0.3	11.9	3.9	2.7	5.2	6.6	2.1	0.8	16.7	8.2	8.2	3.6	19.3	9.3	0.7	36.0	15.4	3.1	2.6	0.2	1.8	6.1	20.6	6.9	0.1	2.7	6.8	11.7	19.2	2.0	10.6	4.6	8.6	4.2	2.2	11.3	18.2	1.1	6.0	9.7	0.0	15.8	0.9	7.7	13.1	6.9	0.2	4.7	4.5	0.9	15.3	9.3	4.1	10.2	7.0	4.1	8.3	15.3	7.5	13.7	16.3	9.3	6.3	12.2	14.2	13.2	8.9	15.3	14.4	1.4	19.9	10.2	11.0	14.7	12.8	13.3	15.4	13.6	16.6	12.3	13.8	14.6	14.2	13.1	14.0	16.0	14.8	18.8	12.8	13.7	10.1	6.7	6.6	9.5	21.1	4.0	1.0	25.0	14.9	44.0	27.1	13.0	18.4	0.0	78.8	9.8	303.1	50.9	35.2	23.5	12.8	8.2	13.4	45.6	38.5	2.3	32.6	31.3	18.1	28.5	10.8	19.1	12.8	19.2	203.3	55.1	1.7	2.8	105.3	20.3	21.0	8.9	36.5	21.5	15.3	17.8	0.0	26.1	13.6	18.6	3.0	3.6	26.7	185.7	18.0	7.9	8.3	435.0	94.8	7.3	0.6	6.6	13.2	12.7	41.5	8.1	9.4	4.5	75.5	11.9	140.6	185.9	12.7
ACADSB	"ACAD7, SBCAD"	ENSG00000196177	"Acyl-CoA dehydrogenase short/branched chain"	P45954	10	123008979-123058290	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 360.1"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 499.5;Proximal tubular cells: 137.9"	"Cancer enhanced"	"Detected in all"		"liver cancer: 32.5"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"Hep G2: 54.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041458, HPA063555"	Enhanced		Supported	Mitochondria		NA	NA		37000	"Cluster 2: Granulocytes - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 2: Hepatocytes - Metabolism"	Mitochondria		"HPA041458: AB_2677491, HPA063555: "	"unprognostic (1.53e-2)"	"unprognostic (1.31e-1)"	"unprognostic (3.91e-3)"	"unprognostic (2.02e-1)"	"unprognostic (1.25e-1)"	"unprognostic (4.87e-2)"	"unprognostic (4.15e-2)"	"unprognostic (1.32e-3)"	"unprognostic (1.30e-1)"	"unprognostic (3.67e-1)"	"prognostic favorable (3.40e-4)"	"unprognostic (9.37e-3)"	"prognostic favorable (6.37e-12)"	"unprognostic (2.69e-1)"	"unprognostic (7.20e-2)"	"unprognostic (1.60e-3)"	"unprognostic (7.14e-2)"	14.8	27.4	8.0	7.1	8.5	3.8	23.9	13.9	10.3	7.8	13.1	15.9	52.4	9.9	7.7	12.6	9.7	7.6	38.5	8.6	6.7	90.2	360.1	12.7	8.2	6.3	7.6	12.8	15.8	33.4	8.8	5.1	6.8	22.7	16.8	12.4	15.7	11.2	42.4	9.8	11.0	8.5	5.9	6.4	14.0	8.4	8.0	7.4	12.3	69.1	10.3	10.8	8.1	8.4	15.4	10.9	7.9	14.5	10.6	13.1	7.0	9.3	18.8	9.2	9.1	9.6	4.9	16.0	6.3	7.9	5.6	6.3	12.5	6.5	15.1	10.6	12.9	8.3	3.3	54.8	7.5	12.0	7.6	9.7	6.5	5.8	5.3	13.5	9.0	13.2	8.1	11.5	11.5	7.1	11.4	9.8	4.8	8.5	6.7	13.4	16.6	5.1	13.1	16.9	1.4	9.1	14.3	4.2	14.4	7.5	12.9	5.8	9.5	4.9	4.4	11.4	11.4	12.9	15.5	8.5	7.6	11.1	3.8	17.4	4.5	11.8	8.8	4.7	10.2	5.5	8.1	7.6	6.4	5.7	7.4	8.3	2.9	8.5	2.9	3.8	7.1	5.7	8.0	8.5	13.9	10.3	8.6	6.7	6.3	7.6	6.8	5.9	8.0	8.4	7.7	28.9	53.1	29.4	11.6	9.3	9.2	8.2	14.2	17.4	58.6	27.8	80.7	37.1	21.1	11.0	10.4	20.1	8.7	11.2	46.9	7.3	7.0	6.8	9.1	8.2	12.1	21.4	39.8	4.8	3.5	10.6	10.7	18.8	3.8	29.1	15.4	499.5	7.3	21.9	49.6	13.7	26.4	17.4	5.9	8.1	13.4	7.1	7.2	12.2	7.9	12.0	7.2	15.6	38.3	4.6	13.1	10.9	9.1	19.8	9.2	137.9	15.2	7.7	19.7	12.3	11.0	8.5	3.7	14.7	13.8	30.1	13.3	18.9	18.3	12.0
ACADVL	"ACAD6, LCACD, VLCAD"	ENSG00000072778	"Acyl-CoA dehydrogenase very long chain"	P49748	17	7217125-7225266	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase	"Cardiomyopathy, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 850.4"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019006, HPA020595"	Enhanced		Supported	Nucleoplasm,Nucleoli,Mitochondria		NA	NA		98000	"Cluster 26: Non-specific - Mitochondria"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 20: HeLa - Mitochondria"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Mitochondria	"Nucleoplasm, Nucleoli"	"HPA019006: AB_1844478, HPA020595: AB_1844479"	"unprognostic (4.81e-2)"	"unprognostic (2.86e-1)"	"unprognostic (2.21e-2)"	"unprognostic (1.09e-2)"	"unprognostic (6.63e-3)"	"unprognostic (1.51e-1)"	"unprognostic (1.89e-2)"	"unprognostic (1.39e-1)"	"unprognostic (1.07e-1)"	"unprognostic (3.21e-1)"	"prognostic favorable (6.87e-4)"	"unprognostic (3.55e-2)"	"unprognostic (1.20e-1)"	"unprognostic (1.34e-1)"	"unprognostic (1.58e-1)"	"unprognostic (4.01e-1)"	"unprognostic (2.84e-3)"	197.9	405.2	120.1	78.7	131.0	103.5	142.9	128.4	126.7	110.5	170.6	157.3	306.2	98.5	44.4	181.0	94.0	92.6	576.8	117.8	125.0	215.3	517.4	106.7	52.0	127.5	125.3	80.9	236.5	159.6	189.6	112.0	124.8	133.2	131.6	34.9	158.5	113.9	850.4	135.7	270.6	110.6	118.2	132.2	186.4	75.9	132.0	83.4	159.3	817.1	82.9	137.1	115.3	122.7	193.7	162.5	65.8	92.4	271.2	99.2	135.9	156.5	169.0	136.9	84.5	67.2	155.3	90.4	109.0	260.0	49.7	147.9	43.8	135.5	119.6	295.9	47.1	50.6	120.9	101.1	131.2	49.0	129.5	112.5	122.0	114.7	178.5	212.6	124.8	111.3	73.3	110.2	222.7	65.3	49.6	68.4	34.3	178.4	91.9	70.4	78.3	227.2	305.1	155.0	19.1	47.3	206.8	224.8	110.8	60.6	102.8	74.9	151.5	127.5	101.6	75.9	149.9	104.5	59.1	5.2	230.7	85.7	94.9	24.2	96.1	121.3	39.1	57.8	35.7	25.2	32.5	43.8	99.9	24.6	23.7	29.1	20.2	37.8	39.3	80.4	31.8	79.4	120.1	131.0	128.4	126.7	117.8	125.0	127.5	125.3	124.8	118.2	132.0	122.7	109.9	60.9	81.9	143.3	72.3	87.3	336.0	322.4	91.6	42.0	157.7	104.5	451.4	138.7	206.7	202.3	62.6	482.9	87.7	484.2	185.9	310.8	133.0	87.2	52.7	77.4	179.3	65.2	40.9	77.0	197.8	118.6	406.7	88.5	88.4	121.1	53.6	365.4	182.4	33.7	33.4	251.8	233.9	67.9	94.6	249.9	124.5	101.5	81.8	34.7	274.9	40.7	73.2	23.1	24.5	106.1	388.9	132.8	172.3	369.0	489.8	345.8	144.1	41.3	105.2	88.3	147.4	114.3	47.8	113.8	87.5	663.3	75.5	169.2	316.8	367.5
ACOX1	PALMCOX	ENSG00000161533	"Acyl-CoA oxidase 1"	Q15067	17	75941507-75979177	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase	"Deafness, Disease variant, Neuropathy"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 191.5"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 199.8;Hepatocytes: 287.4;Proximal enterocytes: 238.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"basophil: 77.2;neutrophil: 113.7"	"Lineage enriched"	"Detected in all"	6	"granulocytes: 113.7"	"Cell line enhanced"	"Detected in all"		"BEWO: 96.9;RT4: 129.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB021094, HPA021192, HPA021195, HPA028759"	Approved		Approved	Nucleoli,Peroxisomes		NA	NA		96000	"Cluster 50: Neutrophils - Cellular senescence"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 15: RT4 - Unknown function"	"Cluster 45: Enterocytes - Digestion"	Peroxisomes	Nucleoli	"CAB021094: AB_10261667, HPA021192: AB_1844527, HPA021195: AB_1844528, HPA028759: AB_10601352"	"unprognostic (7.47e-2)"	"unprognostic (3.69e-1)"	"unprognostic (1.25e-3)"	"unprognostic (1.36e-1)"	"unprognostic (7.49e-2)"	"unprognostic (8.14e-2)"	"unprognostic (3.75e-2)"	"unprognostic (4.95e-2)"	"unprognostic (1.61e-1)"	"unprognostic (5.33e-2)"	"unprognostic (1.25e-1)"	"unprognostic (3.38e-2)"	"prognostic favorable (5.25e-7)"	"unprognostic (3.39e-1)"	"unprognostic (2.41e-2)"	"unprognostic (1.72e-1)"	"unprognostic (4.46e-2)"	37.8	18.1	16.1	10.6	18.2	8.8	17.1	17.4	15.1	11.0	21.3	40.9	62.5	9.3	9.8	30.4	9.9	14.9	23.0	14.3	17.5	40.3	191.5	13.6	6.2	16.6	17.9	9.5	39.7	18.8	12.6	17.3	15.9	18.4	27.1	16.1	15.4	11.8	30.1	24.8	51.4	11.1	17.5	10.5	27.4	9.3	20.6	8.3	17.0	29.2	12.1	19.5	12.7	18.9	16.3	24.5	7.2	9.9	34.0	14.4	96.9	11.8	11.3	12.9	14.8	16.4	24.0	9.1	14.0	17.9	12.5	9.9	28.7	12.4	19.2	10.0	9.5	10.9	13.1	47.2	19.4	9.7	7.8	24.0	9.4	15.7	9.2	13.1	32.3	13.6	12.3	8.9	14.0	45.3	26.3	7.0	4.9	36.8	19.8	13.4	21.3	10.2	20.7	129.1	8.7	12.6	30.6	46.5	11.4	21.2	32.6	11.3	20.9	18.2	13.4	15.2	11.5	14.4	11.0	4.0	10.0	9.7	11.4	77.2	18.3	5.2	6.9	14.2	8.2	5.4	6.6	8.8	10.3	4.5	7.2	7.1	113.7	7.2	9.4	9.4	9.3	8.0	16.1	18.2	17.4	15.1	14.3	17.5	16.6	17.9	15.9	17.5	20.6	18.9	28.0	28.9	25.0	25.1	10.8	13.5	15.9	26.1	21.1	27.4	19.4	13.5	47.4	51.5	23.4	23.9	22.9	37.7	12.1	199.8	21.5	22.9	11.6	18.1	16.7	18.8	34.4	21.5	17.8	40.6	46.5	19.8	88.7	24.1	17.1	21.4	21.8	287.4	25.4	18.5	18.8	44.5	24.4	35.4	14.1	7.1	29.8	23.7	14.2	15.0	36.3	61.9	9.2	22.1	18.2	34.2	100.0	47.0	18.3	24.0	238.7	107.8	17.4	28.4	0.0	18.4	17.2	5.5	11.0	28.5	30.3	43.2	13.2	17.1	41.9	31.7
ACOX2	"BRCACOX, BRCOX, THCCox"	ENSG00000168306	"Acyl-CoA oxidase 2"	Q99424	3	58505136-58537283	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	4	"liver: 177.3"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 89.0;Proximal enterocytes: 27.9;Proximal tubular cells: 51.0"	"Cancer enhanced"	"Detected in many"		"liver cancer: 25.0"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"ASC diff: 16.4;ASC TERT1: 25.9;fHDF/TERT166: 9.2;Hep G2: 10.8;HSkMC: 17.4"	"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"HPA038280, HPA064845"	Enhanced		Approved	Vesicles,Cytosol		No	No		29000		"Cluster 85: Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 2: Hepatocytes - Metabolism"	Vesicles	Cytosol	"HPA038280: AB_10672623, HPA064845: AB_2685368"	"unprognostic (6.62e-2)"	"unprognostic (2.10e-1)"	"unprognostic (1.08e-1)"	"unprognostic (2.51e-2)"	"unprognostic (8.34e-2)"	"unprognostic (1.48e-2)"	"unprognostic (8.67e-3)"	"unprognostic (6.45e-2)"	"unprognostic (1.00e-1)"	"unprognostic (1.85e-1)"	"unprognostic (1.70e-3)"	"unprognostic (1.26e-2)"	"unprognostic (1.68e-3)"	"unprognostic (4.00e-3)"	"unprognostic (2.34e-1)"	"unprognostic (1.26e-1)"	"unprognostic (5.63e-3)"	8.8	8.3	4.1	2.1	4.6	0.1	5.8	4.4	4.5	9.3	16.8	12.9	25.4	9.4	5.8	6.3	10.8	8.2	16.7	4.3	4.5	42.1	177.3	6.2	1.7	5.3	4.8	11.2	4.6	9.6	4.6	3.4	4.4	10.8	8.3	1.8	7.2	9.8	8.2	2.9	21.6	11.2	4.5	1.4	4.0	4.9	4.9	4.0	16.1	17.0	1.2	8.7	6.0	4.1	0.0	0.0	0.2	0.0	16.4	25.9	4.7	3.1	0.2	0.0	0.4	0.8	0.0	0.0	0.0	9.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	10.8	2.3	0.0	0.0	17.4	0.0	0.0	0.0	2.0	0.1	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.2	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.1	4.6	4.4	4.5	4.3	4.5	5.3	4.8	4.4	4.5	4.9	4.1	1.9	3.2	5.8	11.1	0.6	0.6	7.6	0.5	5.7	0.3	1.3	3.8	14.3	4.3	0.9	3.7	0.0	0.7	0.0	4.2	15.6	0.3	0.1	0.4	1.3	1.6	3.0	2.7	0.6	1.9	0.4	8.6	2.0	0.2	1.3	8.6	6.1	89.0	5.2	1.7	0.6	5.1	0.0	1.9	0.4	1.8	10.8	1.7	0.0	1.0	0.5	10.8	0.0	0.5	0.0	0.4	0.8	8.6	0.1	0.6	27.9	51.0	0.0	0.8	6.6	7.0	5.2	0.4	0.4	3.0	0.3	0.8	0.3	9.6	4.6	3.8
ACOX3		ENSG00000087008	"Acyl-CoA oxidase 3, pristanoyl"	O15254	4	8366282-8440723	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Syncytiotrophoblasts: 74.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA035840, HPA035841"	Uncertain		Supported	Peroxisomes		NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"	Peroxisomes		"HPA035840: AB_10696514, HPA035841: AB_10671940"	"unprognostic (3.07e-2)"	"unprognostic (5.51e-2)"	"unprognostic (1.12e-1)"	"prognostic favorable (2.16e-4)"	"unprognostic (5.52e-2)"	"unprognostic (1.81e-3)"	"unprognostic (2.21e-1)"	"unprognostic (3.37e-2)"	"unprognostic (2.27e-1)"	"unprognostic (4.43e-2)"	"unprognostic (4.81e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.46e-2)"	"unprognostic (3.58e-2)"	"unprognostic (2.84e-1)"	"unprognostic (1.69e-1)"	"unprognostic (2.65e-1)"	7.7	8.8	5.8	6.4	5.2	4.4	12.2	3.8	7.2	9.5	5.9	8.4	8.9	5.6	4.3	26.6	6.6	5.9	16.2	5.3	4.9	6.5	14.9	7.2	6.6	5.9	4.6	7.5	12.0	7.1	4.5	8.4	4.7	10.5	6.3	3.8	15.4	8.4	6.4	12.5	8.9	11.4	4.2	5.3	10.1	2.9	5.0	4.6	8.5	5.6	8.5	10.1	13.7	7.1	8.9	9.6	10.5	14.1	11.0	18.7	17.2	11.1	15.1	18.5	16.1	4.8	11.7	11.9	11.7	22.8	25.0	5.4	4.6	14.4	14.3	4.1	4.5	5.2	8.2	14.8	18.3	10.7	9.4	18.9	12.1	16.7	6.5	13.3	22.1	13.1	7.0	10.6	16.1	8.2	11.4	15.6	5.9	11.3	16.4	11.8	17.3	14.3	11.2	12.4	5.1	11.7	14.2	7.2	7.3	8.6	7.2	14.9	21.7	18.2	5.9	7.5	11.8	7.9	5.6	5.4	23.2	13.1	11.8	0.1	13.2	3.3	6.1	15.2	6.3	5.4	7.1	7.8	17.8	4.9	6.5	6.7	3.1	9.5	14.4	21.4	10.4	9.4	5.8	5.2	3.8	7.2	5.3	4.9	5.9	4.6	4.7	4.2	5.0	7.1	6.2	6.4	5.9	14.7	4.8	4.5	7.6	12.3	8.6	8.2	11.6	7.6	9.4	10.0	9.8	11.0	33.3	23.9	7.7	10.9	3.9	17.3	4.4	13.1	4.2	5.6	1.8	3.0	13.2	13.7	9.3	6.6	10.2	10.0	0.0	21.7	4.6	14.2	10.2	1.7	14.2	4.9	14.2	4.1	4.4	3.3	6.8	5.3	5.4	6.5	7.6	3.8	2.1	12.5	14.5	16.9	7.4	11.3	5.6	9.1	18.3	8.2	11.2	18.6	0.0	3.8	6.9	2.4	2.3	14.1	5.8	74.6	6.0	6.0	7.5	11.4
ADH1A	ADH1	ENSG00000187758	"Alcohol dehydrogenase 1A (class I), alpha polypeptide"	P07327	4	99276369-99291003	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	306	"liver: 2739.1"	"Cell type enriched"	"Detected in some"	12	"Hepatocytes: 200.9"	"Cancer enriched"	"Detected in some"	251	"liver cancer: 165.9"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	7	"ASC diff: 8.2"									"CAB009562, HPA047814, HPA060902"	Enhanced		Approved	"Plasma membrane,Cytosol"		NA	NA		38000000		"Cluster 60: Liver - Hemostasis & Lipid metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 2: Hepatocytes - Metabolism"	"Plasma membrane, Cytosol"		"CAB009562: AB_2257984, HPA047814: AB_2680163, HPA060902: AB_2684384"	"unprognostic (5.89e-2)"	"unprognostic (6.16e-2)"		"unprognostic (1.20e-1)"	"unprognostic (2.07e-1)"	"unprognostic (4.40e-1)"	"prognostic favorable (2.38e-4)"	"unprognostic (2.78e-3)"		"unprognostic (4.25e-1)"	"unprognostic (4.79e-3)"	"unprognostic (6.21e-2)"	"unprognostic (9.36e-2)"	"unprognostic (3.25e-2)"	"unprognostic (1.40e-1)"		"unprognostic (2.86e-2)"	7.2	1.6	0.0	0.4	0.0	0.0	1.3	0.0	0.0	0.0	0.0	0.3	8.9	0.3	0.5	0.1	0.5	6.6	0.3	0.0	0.0	0.7	2739.1	0.8	0.0	0.1	0.1	0.1	1.1	0.0	0.3	0.1	0.0	0.0	0.3	0.0	0.2	0.0	0.1	0.1	1.8	0.0	0.1	0.3	0.4	0.3	0.0	0.0	0.1	1.0	0.1	0.3	0.1	0.1	0.0	0.0	0.0	0.0	8.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.4	15.7	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	1.5	0.1	0.1	0.3	0.0	10.7	0.0	0.0	0.0	2.8	0.0	0.0	0.0	0.0	8.6	200.9	0.0	0.0	0.0	0.0	0.0	9.2	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.3	0.2	0.1	0.0	0.0	0.5	0.0	0.0	0.0
ADH1B	ADH2	ENSG00000196616	"Alcohol dehydrogenase 1B (class I), beta polypeptide"	P00325	4	99304971-99352760	"Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 1501.5;liver: 5858.7"	"Cell type enriched"	"Detected in many"	6	"Hepatocytes: 4153.7"	"Cancer enriched"	"Detected in many"	31	"liver cancer: 223.1"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	7	"ASC diff: 6574.3"									"HPA047814, HPA060902"	Supported		Approved	"Plasma membrane,Cytosol"		NA	NA		39000000		"Cluster 85: Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 2: Hepatocytes - Metabolism"	"Plasma membrane, Cytosol"		"HPA047814: AB_2680163, HPA060902: AB_2684384"	"unprognostic (5.13e-2)"	"unprognostic (9.80e-3)"	"unprognostic (6.59e-2)"	"unprognostic (5.56e-2)"	"unprognostic (9.49e-2)"	"unprognostic (5.53e-2)"	"unprognostic (1.54e-3)"	"unprognostic (1.04e-2)"	"unprognostic (6.51e-2)"	"unprognostic (2.73e-2)"	"unprognostic (7.47e-3)"	"unprognostic (7.79e-2)"	"prognostic unfavorable (7.87e-4)"	"unprognostic (4.60e-3)"	"unprognostic (2.33e-1)"	"unprognostic (2.58e-1)"	"unprognostic (1.60e-2)"	1501.5	140.2	2.2	36.4	3.4	0.1	924.6	1.9	9.0	41.0	13.5	202.2	38.5	161.4	74.8	105.8	385.0	145.1	215.3	2.0	1.9	66.7	5858.7	373.2	25.8	4.7	2.2	117.7	49.1	7.8	24.2	6.8	3.2	26.7	114.7	0.1	67.9	26.7	66.6	159.2	237.1	73.4	4.4	72.7	141.1	2.8	2.2	19.8	94.5	228.2	16.0	287.9	118.7	2.4	0.0	0.0	0.0	0.0	6574.3	956.7	0.2	0.0	2.0	0.0	0.0	0.0	0.0	0.7	0.1	1.1	0.0	0.0	0.5	1.4	0.0	0.1	0.0	1.1	0.1	0.0	26.9	3.0	0.0	216.8	0.1	0.0	0.8	0.0	0.0	0.0	0.5	0.0	0.1	0.0	0.1	0.5	0.1	0.0	0.0	0.1	3.2	0.1	0.0	0.0	0.1	0.2	1.3	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.5	0.2	0.2	0.3	1.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.2	3.4	1.9	9.0	2.0	1.9	4.7	2.2	3.2	4.4	2.2	2.4	29.0	0.0	3.4	0.0	8.1	22.3	0.5	0.1	6.8	0.1	1.1	2.5	12.2	110.1	2.3	0.0	0.0	0.1	1.5	0.0	0.0	0.0	0.6	0.1	0.9	14.7	0.0	115.0	0.0	0.0	0.1	633.1	11.2	0.0	1.3	0.0	96.8	4153.7	0.1	0.0	0.0	0.0	0.0	98.8	25.4	0.6	55.3	3.5	28.4	1.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.4	7.1	0.7	0.0	0.1	0.2	0.1	6.6	15.0	47.9	0.0	0.1	10.4	13.1	0.1	8.9	0.1	0.0	0.2
ADH1C	ADH3	ENSG00000248144	"Alcohol dehydrogenase 1C (class I), gamma polypeptide"	P00326	4	99336497-99352746	"Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	21	"intestine: 598.1;liver: 2062.2;stomach 1: 570.6"	"Cell type enhanced"	"Detected in many"		"Exocrine glandular cells: 699.4;Gastric mucus-secreting cells: 611.2;Hepatocytes: 440.6;Undifferentiated cells: 420.5"	"Cancer enriched"	"Detected in many"	7	"liver cancer: 238.2"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"A549: 2.1;ASC TERT1: 3.6;HSkMC: 11.9;RPMI-8226: 2.1"									"HPA047814, HPA060902"	Supported		Supported	"Plasma membrane,Cytosol"		NA	NA		31000000		"Cluster 85: Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 1: Pancreatic cells - Digestion"	"Plasma membrane, Cytosol"		"HPA047814: AB_2680163, HPA060902: AB_2684384"	"unprognostic (3.98e-2)"	"unprognostic (9.88e-3)"	"unprognostic (7.04e-2)"	"unprognostic (1.90e-1)"	"unprognostic (5.14e-1)"	"unprognostic (1.57e-1)"	"prognostic favorable (4.55e-4)"	"prognostic favorable (2.99e-4)"	"unprognostic (8.25e-2)"	"unprognostic (8.89e-3)"	"unprognostic (7.95e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.12e-1)"	"unprognostic (1.21e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.70e-1)"	"unprognostic (9.37e-2)"	22.9	0.8	0.1	29.8	0.1	0.0	19.2	0.1	0.1	4.7	0.0	329.5	598.1	5.1	7.2	5.1	5.8	51.6	5.9	0.1	0.0	19.6	2062.2	2.9	0.6	0.1	0.1	4.0	16.7	0.1	1.6	0.1	0.1	9.4	191.9	0.0	19.3	6.2	23.9	0.7	190.7	16.3	0.1	0.7	570.6	0.8	0.1	0.5	2.9	31.1	0.5	5.9	3.6	0.2	0.0	2.1	0.0	0.0	1.4	3.6	0.9	0.0	0.5	0.0	0.0	0.0	0.0	0.1	0.1	0.2	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.4	0.3	0.0	0.2	1.1	0.3	11.9	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.1	0.0	0.0	0.3	0.8	0.2	0.0	0.1	0.1	0.8	2.1	0.8	0.0	0.3	1.1	0.5	0.7	0.0	0.0	0.2	0.0	0.1	0.0	0.4	0.3	0.1	0.1	0.0	0.3	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.1	0.1	0.0	0.1	0.1	0.1	0.1	0.1	0.2	2.1	3.2	7.3	0.7	1.3	0.0	4.0	0.0	25.0	0.0	0.1	0.3	1.0	64.3	24.8	29.5	0.0	0.0	0.1	108.4	0.0	159.5	2.3	1.3	0.8	1.2	21.6	29.5	0.3	699.4	0.0	21.1	611.2	1.3	0.0	0.0	13.2	440.6	0.0	0.0	0.2	86.3	0.0	13.2	0.0	1.0	10.5	0.8	0.0	0.0	2.0	0.0	0.0	0.5	0.1	66.3	120.8	0.0	0.6	3.1	59.4	1.4	43.7	0.0	0.0	1.3	2.0	0.0	0.7	10.6	0.0	0.0	1.8	1.6	420.5	3.6
ADH4	ADH-2	ENSG00000198099	"Alcohol dehydrogenase 4 (class II), pi polypeptide"	P08319	4	99123657-99157792	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	31	"liver: 5151.4"	"Cell type enriched"	"Detected in some"	21	"Hepatocytes: 975.2"	"Cancer enriched"	"Detected in some"	60	"liver cancer: 230.7"	"Low region specificity"	"Detected in some"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	13	"Hep G2: 22.2"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			HPA020525	Enhanced		Uncertain	Nucleoplasm,Cytosol		NA	NA		20000000	"Cluster 34: Basophils - Unknown function"	"Cluster 60: Liver - Hemostasis & Lipid metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 2: Hepatocytes - Metabolism"	"Nucleoplasm, Cytosol"		"HPA020525: AB_1844609"	"unprognostic (2.75e-1)"	"unprognostic (1.69e-2)"	"unprognostic (1.85e-2)"	"unprognostic (5.54e-3)"	"unprognostic (2.14e-2)"	"unprognostic (1.33e-2)"	"prognostic favorable (7.08e-6)"	"unprognostic (1.49e-1)"		"unprognostic (1.39e-2)"	"unprognostic (6.91e-2)"	"unprognostic (1.88e-1)"	"unprognostic (2.34e-2)"	"unprognostic (7.16e-3)"	"unprognostic (2.20e-1)"		"unprognostic (5.89e-3)"	2.1	0.8	0.5	0.4	0.4	0.4	4.3	1.2	1.0	1.5	0.0	0.6	164.1	0.2	0.5	0.8	0.3	0.4	0.2	0.4	0.7	1.5	5151.4	0.2	0.2	0.1	0.1	0.1	0.4	0.1	0.0	0.2	0.1	0.3	0.6	0.8	2.6	0.5	0.6	0.9	22.9	0.1	0.0	0.6	0.6	1.0	0.5	0.0	0.4	2.1	0.1	0.3	3.4	0.2	0.1	0.2	0.1	0.2	0.1	0.0	0.2	0.1	0.0	0.0	0.0	0.1	0.1	0.4	0.2	0.0	0.1	0.1	0.0	0.1	0.2	0.0	0.0	0.4	0.4	22.2	0.0	1.6	0.2	0.2	0.0	0.1	0.1	0.1	0.0	0.1	0.3	0.8	0.0	0.1	0.1	0.5	0.3	0.0	0.1	0.1	1.6	0.5	0.0	0.1	0.1	0.2	1.5	0.3	0.0	0.1	0.4	0.0	0.1	0.4	0.1	0.3	0.0	0.4	0.4	0.6	0.0	0.5	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.4	1.2	1.0	0.4	0.7	0.1	0.1	0.1	0.0	0.5	0.2	0.0	0.0	0.0	0.0	2.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	21.5	0.2	1.8	0.0	0.0	0.0	0.8	0.0	0.0	26.9	0.7	0.6	1.1	0.0	45.5	0.1	0.6	0.0	1.0	0.0	0.3	0.0	0.0	16.1	975.2	0.0	0.0	0.0	1.1	0.0	27.0	0.0	3.7	0.3	0.1	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.9	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.0	1.9	0.0	0.8	0.0
ADH5	"ADH-3, ADHX, FDH, GSNOR"	ENSG00000197894	"Alcohol dehydrogenase 5 (class III), chi polypeptide"	P11766	4	99070978-99088801	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA044578, HPA061919"	Approved					NA	NA		5300000	"Cluster 48: NK-cells - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 39: Non-specific - Basic cellular processes"			"HPA044578: AB_2679002, HPA061919: AB_2684638"	"unprognostic (1.05e-1)"	"unprognostic (1.63e-2)"	"unprognostic (1.14e-3)"	"prognostic favorable (9.90e-5)"	"unprognostic (2.63e-1)"	"unprognostic (1.58e-2)"	"unprognostic (1.11e-1)"	"unprognostic (9.48e-2)"	"prognostic unfavorable (3.54e-4)"	"unprognostic (1.47e-1)"	"unprognostic (1.02e-2)"	"unprognostic (1.22e-1)"	"prognostic favorable (4.58e-10)"	"unprognostic (1.79e-3)"	"unprognostic (9.05e-2)"	"unprognostic (1.15e-2)"	"unprognostic (1.13e-1)"	141.5	71.3	48.3	52.5	48.2	28.5	111.9	48.0	56.0	92.7	55.8	158.8	94.2	134.8	142.2	114.4	95.9	69.3	124.3	45.9	54.6	175.4	264.1	73.5	51.3	47.6	48.5	118.4	49.4	50.1	41.4	60.9	47.9	116.2	100.8	36.0	65.4	124.6	80.9	54.8	94.3	118.0	49.7	51.6	91.3	52.2	48.6	83.3	79.2	75.8	55.5	158.9	73.9	51.4	84.0	66.9	194.8	110.0	344.7	316.0	116.6	136.6	237.6	143.8	125.2	77.1	96.7	96.5	77.5	197.8	92.8	69.8	135.0	188.7	137.7	69.9	56.6	67.1	83.3	306.7	332.2	118.4	51.9	287.3	143.1	108.3	84.7	151.0	112.8	99.8	125.8	53.3	192.3	94.9	160.4	105.4	156.7	20.6	79.8	115.4	108.9	50.9	230.2	96.0	74.0	97.0	82.7	96.6	155.9	141.8	78.2	82.2	85.4	130.5	82.9	86.4	95.2	55.9	74.4	135.4	134.2	77.4	135.7	21.8	21.2	35.8	32.6	18.9	29.5	26.0	35.3	30.4	23.8	26.2	34.0	31.9	3.0	51.3	14.1	20.5	49.5	32.8	48.3	48.2	48.0	56.0	45.9	54.6	47.6	48.5	47.9	49.7	48.6	51.4	69.0	105.8	78.2	22.9	48.1	39.6	85.9	257.5	109.3	31.8	32.1	74.3	127.4	78.6	94.3	55.2	10.4	290.1	51.8	80.4	197.6	94.8	24.0	146.9	159.1	56.3	79.7	45.8	14.3	83.8	277.2	131.2	37.8	113.0	26.6	83.3	47.2	188.0	118.1	38.7	12.0	101.8	87.5	48.6	27.1	22.0	187.4	43.4	53.4	15.9	63.2	152.4	77.2	27.6	13.9	78.4	86.0	255.1	41.5	34.9	95.2	316.0	56.8	46.5	111.7	55.6	127.7	30.5	48.5	74.9	23.0	83.0	58.5	147.0	104.8	68.1
ADH6	ADH-5	ENSG00000172955	"Alcohol dehydrogenase 6 (class V)"	P28332	4	99202638-99219537	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	13	"liver: 703.8"	"Group enriched"	"Detected in some"	6	"Hepatocytes: 325.5;Proximal tubular cells: 92.4"	"Cancer enriched"	"Detected in many"	18	"liver cancer: 46.9"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	5	"Hep G2: 44.7"	"Not detected"	"Not detected"							"HPA067946, HPA069081"	Enhanced					NA	NA		3400000		"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 2: Hepatocytes - Metabolism"			"HPA067946: AB_2732776, HPA069081: AB_2732127"	"unprognostic (1.38e-2)"	"unprognostic (1.83e-2)"	"unprognostic (5.82e-2)"	"unprognostic (1.49e-3)"	"unprognostic (8.49e-2)"	"unprognostic (1.08e-1)"	"unprognostic (5.11e-3)"	"unprognostic (2.40e-1)"	"unprognostic (3.60e-2)"	"unprognostic (1.35e-1)"	"unprognostic (9.72e-3)"	"unprognostic (1.67e-1)"	"unprognostic (3.66e-3)"	"unprognostic (1.35e-1)"	"unprognostic (2.43e-1)"	"unprognostic (8.74e-3)"	"unprognostic (3.86e-3)"	0.2	0.0	0.1	0.6	0.0	0.0	0.1	0.0	0.0	0.2	0.0	8.2	41.5	0.3	0.0	0.3	9.2	7.7	0.0	0.0	0.0	52.3	703.8	0.2	0.2	0.1	0.2	0.0	0.3	0.0	0.0	0.2	0.1	0.1	8.6	0.0	0.0	0.1	0.0	1.8	22.6	0.3	0.1	0.1	0.3	0.2	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.3	0.0	0.5	0.2	0.2	0.0	0.0	0.0	0.3	0.0	0.0	0.0	2.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	44.7	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2	0.3	0.1	9.0	0.1	0.0	0.3	0.1	0.0	0.0	0.1	0.0	0.0	0.1	0.2	0.0	0.0	0.0	0.1	0.0	0.2	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.1	0.1	0.0	0.3	0.0	0.0	0.5	0.0	0.7	0.5	0.1	0.5	0.0	0.0	0.0	0.0	0.3	15.7	1.1	5.5	0.0	0.0	0.0	7.8	7.9	0.3	0.0	11.2	0.3	0.4	12.1	0.0	0.1	0.2	0.0	0.1	0.0	0.4	0.0	0.0	7.1	325.5	0.0	0.0	0.1	8.9	8.2	5.3	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	2.2	0.0	0.0	0.0	31.1	92.4	15.6	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.1	0.0	0.9	0.0	12.7	0.1
ADH7	ADH-4	ENSG00000196344	"Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide"	P40394	4	99412261-99435737	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	5	"esophagus: 196.3"	"Group enriched"	"Detected in some"	4	"Basal respiratory cells: 89.0;Club cells: 64.1;Squamous epithelial cells: 209.1"	"Cancer enhanced"	"Detected in some"		"cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	7	"ASC TERT1: 1.0;HaCaT: 1.2"	"Not detected"	"Not detected"							HPA039695	Enhanced		Supported	"Plasma membrane,Cytosol"		NA	NA				"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 61: Squamous epithelial cells - Keratinization"	"Plasma membrane, Cytosol"		"HPA039695: AB_10795681"		"unprognostic (1.02e-2)"			"unprognostic (8.64e-2)"	"unprognostic (4.86e-2)"	"unprognostic (5.66e-3)"	"unprognostic (4.50e-2)"	"unprognostic (1.66e-1)"					"unprognostic (2.02e-1)"			"unprognostic (1.88e-2)"	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.6	0.0	0.0	0.0	0.0	0.0	196.3	0.1	0.0	0.0	0.0	0.0	0.0	0.5	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	22.8	0.0	0.0	0.7	0.0	0.0	0.0	0.0	27.3	0.0	0.0	0.2	0.0	0.0	38.1	0.3	4.6	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.0	89.0	21.1	0.0	0.0	0.0	0.2	0.0	64.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.0	0.1	0.0	0.0	0.1	7.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.1	0.0	18.3	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	1.2	0.6	0.0	0.0	26.2	0.0	0.0	0.0	2.3	0.0	0.0	209.1	0.0	0.0	0.0	0.0	0.0	1.0
ADHFE1	FLJ32430	ENSG00000147576	"Alcohol dehydrogenase iron containing 1"	Q8IWW8	8	66432492-66468907	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 31.2;skeletal muscle: 29.2;tongue: 31.3"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 76.4;Cardiomyocytes: 41.6;Syncytiotrophoblasts: 116.4"	"Cancer enhanced"	"Detected in many"		"liver cancer: 7.9"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"ASC diff: 1.2;RPTEC TERT1: 1.5"					"Low region specificity"	"Detected in all"			HPA023062	Enhanced		Approved	Vesicles		NA	NA			"Cluster 24: B-cells - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"	Vesicles		"HPA023062: AB_1844611"	"prognostic favorable (5.76e-5)"	"unprognostic (8.69e-2)"	"unprognostic (6.71e-2)"	"unprognostic (2.70e-1)"	"unprognostic (1.14e-1)"	"unprognostic (1.22e-1)"	"prognostic favorable (9.90e-5)"	"unprognostic (7.76e-3)"	"unprognostic (2.88e-1)"	"unprognostic (1.32e-1)"	"unprognostic (1.59e-1)"	"unprognostic (9.43e-2)"	"prognostic favorable (4.55e-5)"	"unprognostic (1.37e-2)"	"unprognostic (2.06e-1)"	"unprognostic (4.66e-2)"	"unprognostic (5.94e-3)"	7.0	2.3	8.7	0.3	8.5	0.0	3.9	7.2	11.7	2.3	10.4	3.9	0.6	2.0	1.3	1.3	5.6	0.7	24.5	8.2	8.2	6.6	31.2	2.1	0.3	8.3	8.5	5.1	9.4	5.0	2.6	1.1	8.1	5.2	0.7	1.5	2.3	1.5	29.2	1.1	2.5	0.2	7.8	1.8	11.0	1.7	8.7	0.3	2.7	31.3	0.3	4.4	1.8	8.5	0.0	0.0	0.0	0.0	1.2	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.6	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.6	0.0	0.0	0.1	0.0	0.3	0.0	0.0	0.8	0.0	0.0	0.5	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.1	0.0	0.0	0.1	0.3	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.6	0.2	0.0	0.2	0.0	0.5	0.1	0.0	0.3	0.0	0.4	0.1	0.3	0.0	0.7	0.0	0.0	0.0	0.0	8.7	8.5	7.2	11.7	8.2	8.2	8.3	8.5	8.1	7.8	8.7	8.5	1.5	9.6	20.1	76.4	1.8	1.0	4.1	2.7	3.4	1.7	4.6	4.6	41.6	14.3	9.6	9.2	10.4	8.8	6.5	1.0	11.7	1.5	0.5	2.5	1.6	3.3	3.6	2.5	8.3	0.6	0.9	5.3	8.6	2.5	8.8	6.1	6.1	27.1	2.5	0.0	13.2	2.0	4.1	2.1	2.8	1.6	23.9	2.1	0.0	14.0	2.0	7.6	6.2	21.6	19.2	0.9	5.8	27.1	3.0	3.5	4.1	14.8	14.3	8.5	0.0	7.8	5.2	0.5	0.6	1.9	1.0	116.4	10.0	2.5	2.4	2.5
ADI1	"APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, mtnD, SIPL"	ENSG00000182551	"Acireductone dioxygenase 1"	Q9BV57	2	3497366-3519531	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Amino-acid biosynthesis, Methionine biosynthesis"	"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 590.7"	"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 888.3;Hepatocytes: 1234.6;Proximal tubular cells: 1546.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA035403, HPA035404"	Approved		Supported	"Nucleoplasm,Golgi apparatus"		NA	NA		130000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 85: Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Nucleoplasm	"Golgi apparatus"	"HPA035403: AB_10603576, HPA035404: AB_2674611"	"unprognostic (2.19e-2)"	"unprognostic (1.68e-2)"	"unprognostic (2.60e-2)"	"unprognostic (1.75e-1)"	"unprognostic (3.65e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.16e-3)"	"unprognostic (4.23e-3)"	"unprognostic (2.36e-3)"	"unprognostic (4.00e-3)"	"unprognostic (2.97e-2)"	"unprognostic (1.50e-1)"	"unprognostic (1.90e-2)"	"unprognostic (1.56e-1)"	"unprognostic (9.94e-2)"	"unprognostic (6.76e-2)"	"unprognostic (8.74e-2)"	55.1	76.9	31.1	28.0	32.6	31.7	50.4	31.7	42.1	54.2	43.3	58.3	105.2	45.6	43.3	48.2	45.2	66.7	146.4	32.0	31.0	200.2	590.7	44.6	30.1	33.0	32.2	50.0	34.9	49.6	33.5	41.3	33.6	101.1	52.3	17.1	53.6	55.9	121.1	35.7	68.9	37.9	31.6	57.2	82.4	16.7	31.6	26.9	36.5	56.0	34.5	57.9	36.5	34.7	46.5	64.5	55.9	50.2	187.5	85.0	91.9	95.6	124.1	102.7	74.5	86.9	59.2	22.1	143.4	109.5	21.4	45.1	62.9	49.0	59.2	39.5	131.4	67.6	42.2	184.1	165.4	71.2	151.3	91.4	72.3	55.0	63.7	45.3	75.8	36.1	51.8	45.3	87.4	137.8	25.6	147.1	44.4	131.9	86.4	27.1	31.3	128.2	90.2	83.3	57.0	54.0	53.0	75.0	37.2	36.8	55.6	95.5	54.1	75.9	29.0	35.9	56.6	35.4	91.6	88.7	58.6	115.5	41.0	87.6	134.3	336.9	28.5	126.5	31.8	66.8	67.4	26.7	127.7	53.4	79.3	25.6	59.4	54.5	117.4	186.3	67.4	189.0	31.1	32.6	31.7	42.1	32.0	31.0	33.0	32.2	33.6	31.6	31.6	34.7	44.8	67.3	111.1	25.1	73.1	76.0	154.5	107.8	92.2	9.2	103.0	88.9	275.8	338.8	109.5	152.6	14.6	395.0	80.6	140.1	888.3	157.2	8.8	65.9	116.3	61.6	57.2	123.1	9.4	87.2	247.1	129.1	66.3	116.3	41.8	75.1	207.8	1234.6	263.2	8.4	15.0	146.1	236.0	168.8	67.6	23.8	137.0	90.0	204.5	7.5	108.2	197.2	40.2	5.5	19.0	79.7	272.5	210.3	97.4	143.6	409.8	1546.8	38.0	15.3	164.3	45.5	109.3	5.3	11.3	113.6	76.9	381.4	53.0	120.8	147.2	156.9
ADO	"C10orf22, FLJ14547"	ENSG00000181915	"2-aminoethanethiol dioxygenase"	Q96SZ5	10	62804720-62808479	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Group enriched"	"Detected in many"	6	"Early spermatids: 186.2;Late spermatids: 317.6;Spermatocytes: 90.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in all"		"PC-3: 99.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA039194, HPA040437"	Approved					NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 21: Non-specific - Transcription"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 31: Spermatids - Spermatogenesis"			"HPA039194: AB_10794994, HPA040437: AB_10795633"	"unprognostic (4.41e-2)"	"unprognostic (1.44e-1)"	"unprognostic (9.25e-2)"	"unprognostic (1.73e-2)"	"unprognostic (1.54e-2)"	"unprognostic (1.57e-1)"	"prognostic unfavorable (8.01e-5)"	"unprognostic (4.48e-2)"	"unprognostic (1.19e-1)"	"unprognostic (1.29e-1)"	"unprognostic (4.24e-2)"	"unprognostic (8.64e-2)"	"unprognostic (8.68e-2)"	"unprognostic (4.11e-2)"	"unprognostic (7.46e-2)"	"unprognostic (2.64e-1)"	"unprognostic (4.59e-2)"	8.9	8.4	12.8	7.6	17.8	5.1	9.2	20.5	17.0	8.4	7.5	7.2	7.0	8.7	13.1	6.7	7.0	7.4	14.5	11.8	14.6	11.3	7.4	7.7	10.0	19.7	17.7	10.5	7.9	12.4	4.0	7.2	18.3	9.7	6.3	10.5	6.4	8.8	11.7	6.1	6.5	9.3	19.0	8.5	7.4	37.6	16.3	8.9	11.9	17.4	9.9	8.6	4.9	28.0	14.3	10.3	20.1	33.2	21.6	16.3	11.9	17.3	20.5	18.2	19.7	16.2	11.2	13.3	8.9	17.8	14.4	21.6	21.0	13.3	19.3	18.3	15.8	9.1	10.8	13.7	22.3	31.3	22.8	14.0	25.3	19.1	30.7	27.8	14.0	17.3	16.8	12.5	24.4	13.6	20.5	30.5	18.7	13.7	99.1	23.9	16.1	8.2	17.6	9.0	20.9	34.3	17.4	23.8	36.4	16.1	15.5	21.5	12.1	18.3	18.9	15.0	29.0	22.8	44.8	21.1	22.2	32.8	12.0	0.8	0.8	0.2	0.4	1.3	0.8	1.3	0.5	0.6	0.9	0.8	0.4	0.8	0.0	0.8	0.9	0.6	0.3	0.4	12.8	17.8	20.5	17.0	11.8	14.6	19.7	17.7	18.3	19.0	16.3	28.0	7.6	9.6	7.3	3.9	7.2	15.9	11.9	4.3	9.6	23.4	9.9	7.1	32.2	5.7	4.3	14.7	6.2	9.1	8.5	5.3	19.6	6.6	186.2	2.7	13.2	9.0	4.9	4.0	9.5	5.3	7.9	11.5	8.2	4.4	2.5	9.2	10.8	3.7	12.7	32.0	7.8	6.8	0.0	11.9	13.3	317.6	10.5	10.9	12.4	3.7	11.3	12.5	7.2	6.0	22.4	7.5	3.4	26.7	3.2	12.1	4.8	15.8	5.6	17.7	13.1	13.0	11.7	90.5	8.4	9.4	21.7	3.8	8.9	12.5	8.4	10.8
AGMO	"FLJ16237, TMEM195"	ENSG00000187546	"Alkylglycerol monooxygenase"	Q6ZNB7	7	15200317-15562015	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	8	"liver: 122.5"	"Cell type enhanced"	"Detected in some"		"Hepatocytes: 83.0;Oligodendrocyte precursor cells: 33.7;Oligodendrocytes: 38.5;Proximal enterocytes: 30.5;Proximal tubular cells: 16.9"	"Cancer enriched"	"Detected in many"	5	"liver cancer: 15.7"	"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in single"		"basophil: 1.4"	"Lineage enriched"	"Detected in single"	8	"granulocytes: 1.4"	"Cell line enhanced"	"Detected in some"		"HSkMC: 3.5;Karpas-707: 7.7;NTERA-2: 3.5;SCLC-21H: 3.2;TIME: 4.0;WM-115: 15.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA057900			Uncertain	Vesicles		NA	NA			"Cluster 10: Basophils - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 17: WM-115 - Nervous system development"	"Cluster 2: Hepatocytes - Metabolism"	Vesicles		"HPA057900: "	"unprognostic (2.82e-1)"	"unprognostic (9.28e-2)"	"unprognostic (5.60e-3)"	"unprognostic (1.44e-4)"	"unprognostic (7.52e-2)"	"unprognostic (1.07e-2)"	"unprognostic (3.61e-2)"	"unprognostic (6.56e-2)"	"unprognostic (3.31e-1)"	"unprognostic (3.35e-1)"	"unprognostic (4.18e-3)"	"unprognostic (3.24e-1)"	"unprognostic (1.64e-1)"	"unprognostic (2.04e-2)"	"unprognostic (3.45e-1)"	"unprognostic (1.00e-1)"	"unprognostic (1.93e-1)"	2.8	0.1	0.9	0.6	2.4	0.1	1.8	0.7	1.9	0.1	0.1	1.2	9.7	0.1	14.5	0.1	0.1	3.6	0.4	0.7	1.4	8.9	122.5	0.2	0.5	1.5	1.4	0.1	0.1	0.0	0.4	0.8	1.5	0.0	0.6	0.1	0.2	0.1	0.3	0.2	14.9	0.1	0.9	0.0	0.3	3.0	1.8	0.2	0.4	0.4	0.1	1.2	0.1	4.1	0.0	2.2	0.0	1.9	0.2	2.7	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.3	0.0	0.0	3.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	7.7	0.0	0.0	0.0	0.1	3.5	0.0	0.0	0.0	0.0	1.2	0.0	0.7	3.2	0.0	0.0	0.0	0.0	2.4	0.0	0.0	4.0	1.3	0.2	0.1	0.0	0.6	0.0	0.0	0.0	0.0	15.4	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.1	0.0	0.0	0.0	0.0	0.9	2.4	0.7	1.9	0.7	1.4	1.5	1.4	1.5	0.9	1.8	4.1	10.0	0.0	0.0	6.8	0.3	0.1	0.1	0.7	0.0	0.0	0.2	0.3	0.1	11.5	0.4	3.7	0.0	0.1	0.1	0.5	0.0	0.0	1.3	0.3	0.1	1.2	1.8	2.7	1.3	0.0	0.2	1.2	0.0	0.0	0.0	0.0	1.1	83.0	0.1	0.0	1.7	0.4	0.0	1.6	0.5	1.0	0.0	0.1	3.6	0.0	0.0	0.0	0.0	33.7	38.5	0.9	0.1	0.0	0.0	0.0	30.5	16.9	0.3	0.0	6.6	0.4	2.4	1.7	6.4	0.1	0.0	0.1	0.2	0.1	0.6	0.0
AKR1A1	"ALR, DD3"	ENSG00000117448	"Aldo-keto reductase family 1 member A1"	P14550	1	45550543-45570049	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Proximal enterocytes: 872.9;Proximal tubular cells: 1215.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB006246, HPA017919, HPA019649, HPA027734"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA		7600000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Cytosol	Nucleoplasm	"CAB006246: AB_425840, HPA017919: AB_1844695, HPA019649: AB_1844696, HPA027734: AB_10600976"	"unprognostic (1.73e-1)"	"prognostic favorable (2.66e-6)"	"unprognostic (4.03e-1)"	"prognostic favorable (2.92e-4)"	"unprognostic (1.17e-1)"	"unprognostic (1.77e-2)"	"unprognostic (6.54e-3)"	"unprognostic (1.31e-3)"	"unprognostic (2.52e-1)"	"unprognostic (1.24e-1)"	"unprognostic (1.83e-1)"	"unprognostic (8.43e-2)"	"unprognostic (4.51e-2)"	"unprognostic (1.56e-2)"	"unprognostic (2.46e-1)"	"unprognostic (2.89e-2)"	"unprognostic (4.57e-2)"	68.8	72.7	37.6	73.4	41.4	48.6	123.1	41.3	38.9	84.0	49.1	106.6	188.7	59.9	90.7	151.9	88.9	61.7	67.6	37.2	41.0	323.5	323.7	75.8	97.3	44.0	39.3	61.8	158.1	60.8	99.4	63.9	44.1	75.9	115.4	23.2	123.0	60.0	46.5	73.5	171.6	79.0	43.3	92.5	112.9	21.1	44.4	77.3	80.7	42.6	117.0	72.3	70.9	53.2	74.3	94.5	91.2	73.7	173.1	124.8	67.9	78.3	178.0	68.8	133.5	40.1	50.3	179.5	68.5	86.2	71.6	94.5	94.0	118.3	60.0	74.3	92.6	101.2	82.2	167.8	152.0	132.4	102.7	140.2	104.7	87.0	157.4	123.4	154.7	125.1	59.4	131.2	77.1	49.1	147.3	61.2	106.0	219.4	68.2	170.1	119.5	211.9	185.5	89.3	117.5	65.3	71.8	271.1	108.5	113.2	80.3	72.3	97.2	30.2	72.0	113.1	54.2	97.0	140.5	87.6	59.1	168.7	26.6	141.8	229.5	45.4	65.3	224.5	71.6	99.8	59.6	63.5	196.8	108.9	51.4	52.4	11.1	66.1	174.8	170.0	81.9	182.7	37.6	41.4	41.3	38.9	37.2	41.0	44.0	39.3	44.1	43.3	44.4	53.2	53.0	48.1	57.3	7.2	96.6	49.2	99.3	210.0	87.6	21.2	121.0	94.7	46.1	95.8	173.8	79.1	37.5	115.2	45.1	113.7	181.9	195.9	5.4	48.7	49.1	58.6	118.4	48.0	8.3	156.5	142.1	82.0	135.5	54.7	112.1	59.2	78.1	294.5	399.3	16.8	7.1	201.9	118.0	141.8	153.7	9.6	68.3	142.1	81.8	20.6	140.3	33.6	49.4	9.0	16.2	123.6	199.9	56.1	187.2	115.1	872.9	1215.0	131.6	38.0	6.6	40.3	132.5	5.9	32.2	158.5	47.0	67.9	49.5	59.0	198.5	129.6
AKR1B1	"ALDR1, AR"	ENSG00000085662	"Aldo-keto reductase family 1 member B"	P15121	7	134442356-134459284	"Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	8	"adrenal gland: 3039.1"	"Cell type enhanced"	"Detected in many"		"Collecting duct cells: 649.2;Cytotrophoblasts: 1105.1;Extravillous trophoblasts: 1284.9;Ionocytes: 697.8;Syncytiotrophoblasts: 2022.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"A549: 1667.3;BJ hTERT+: 3096.2;RPTEC TERT1: 1447.8;U-87 MG: 1343.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA026425, CAB027391, CAB047353, HPA052751"	Enhanced		Supported	Nucleoplasm,Cytosol		No	No		1500000	"Cluster 44: Non-specific - Transcription"	"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 38: Extravillous trophoblasts - Unknown function"	Cytosol	Nucleoplasm	"CAB027391: , CAB047353: , HPA026425: AB_10601563, HPA052751: AB_2681935"	"unprognostic (2.76e-2)"	"unprognostic (2.84e-2)"	"unprognostic (2.02e-2)"	"unprognostic (1.37e-2)"	"unprognostic (6.81e-2)"	"unprognostic (2.26e-1)"	"unprognostic (4.18e-2)"	"unprognostic (5.09e-2)"	"unprognostic (2.51e-3)"	"unprognostic (2.47e-1)"	"unprognostic (2.98e-2)"	"unprognostic (8.78e-2)"	"unprognostic (2.81e-2)"	"prognostic unfavorable (2.44e-5)"	"unprognostic (2.03e-1)"	"unprognostic (1.39e-1)"	"prognostic unfavorable (7.00e-4)"	65.1	3039.1	83.1	38.4	89.3	21.9	52.3	91.8	97.4	41.4	80.9	40.1	20.5	42.4	44.0	28.2	38.7	40.2	208.2	84.1	92.5	218.0	19.3	55.0	74.6	101.6	96.9	60.5	34.4	111.2	76.5	203.7	104.9	34.4	30.9	36.5	41.9	332.7	330.0	26.6	50.8	39.6	91.4	62.8	51.4	44.9	88.7	54.9	44.3	396.9	62.5	67.3	35.0	101.4	184.2	1667.3	186.5	261.4	785.9	212.3	494.6	177.2	3096.2	259.3	335.0	75.8	170.6	0.0	79.2	301.5	1143.3	78.6	204.0	175.3	206.6	65.2	168.2	93.4	225.0	230.1	1117.9	0.1	0.8	196.9	133.4	367.6	98.3	252.8	370.3	181.1	0.1	62.4	292.4	3.5	283.3	131.0	309.2	13.9	1.8	292.9	116.5	138.8	1447.8	915.5	137.1	301.6	1261.5	1.5	134.3	121.3	0.6	140.6	289.6	254.5	116.0	22.7	195.6	168.2	196.9	470.0	1343.5	0.7	153.0	125.7	106.4	5.6	147.6	72.3	135.2	133.0	124.7	144.5	145.3	121.7	162.9	156.7	8.5	119.7	39.2	20.4	94.9	230.2	83.1	89.3	91.8	97.4	84.1	92.5	101.6	96.9	104.9	91.4	88.7	101.4	34.1	12.8	19.4	9.1	50.3	20.6	55.3	66.1	20.5	36.2	11.7	27.9	202.4	25.8	26.4	649.2	8.4	1105.1	35.1	2.3	164.4	112.7	5.0	6.1	20.9	50.9	31.0	20.2	10.5	41.5	1284.9	100.3	20.4	5.9	53.8	59.8	82.1	2.6	394.1	72.3	18.7	15.1	697.8	172.8	53.9	14.5	79.2	127.7	30.2	14.0	76.3	49.3	66.9	5.5	12.4	51.0	4.5	77.5	72.6	25.6	0.3	60.2	24.9	24.1	59.2	98.9	54.5	22.6	100.2	10.5	11.6	2022.4	49.9	70.5	6.7	54.2
AKR1B10	"AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI"	ENSG00000198074	"Aldo-keto reductase family 1 member B10"	O60218	7	134527567-134541412	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 224.5;intestine: 614.8;stomach 1: 432.5"	"Cell type enhanced"	"Detected in many"		"Cholangiocytes: 193.0;Distal enterocytes: 201.0;Gastric mucus-secreting cells: 542.3;Proximal enterocytes: 327.1"	"Cancer enhanced"	"Detected in many"		"liver cancer: 353.4"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	104	"A549: 2959.1;Hep G2: 835.6;OE19: 3141.0"	"Low region specificity"	"Detected in all"							"HPA020280, CAB070163, HPA073633"	Enhanced		Supported	"Plasma membrane,Cytosol"	"Secreted to digestive system"	NA	NA		67000000		"Cluster 37: Intestine - Unknown function"	"Cluster 21: OE19 - Mitochondria"	"Cluster 45: Enterocytes - Digestion"	Cytosol	"Plasma membrane"	"CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620"	"unprognostic (1.29e-2)"	"unprognostic (1.50e-1)"	"prognostic favorable (1.91e-4)"	"unprognostic (6.03e-2)"	"unprognostic (4.67e-2)"	"unprognostic (2.57e-1)"	"unprognostic (2.16e-3)"	"unprognostic (1.01e-1)"	"unprognostic (1.47e-1)"	"unprognostic (3.18e-2)"	"unprognostic (4.65e-3)"	"unprognostic (1.54e-1)"	"prognostic unfavorable (4.80e-9)"	"unprognostic (2.12e-1)"	"unprognostic (2.12e-1)"	"unprognostic (1.43e-2)"	"unprognostic (1.25e-1)"	0.9	5.5	0.1	7.9	0.0	0.2	0.4	0.3	0.1	73.9	0.0	73.4	614.8	0.5	0.1	224.5	0.9	176.1	0.2	0.1	0.1	12.2	40.0	0.4	0.3	0.0	0.0	0.2	0.7	0.0	4.8	0.1	0.1	1.3	45.6	0.1	32.4	0.2	3.7	7.7	354.8	3.2	0.1	0.1	432.5	0.6	0.0	5.5	0.6	5.9	7.7	65.8	145.6	0.2	0.0	2959.1	0.0	0.0	0.7	2.3	9.0	0.3	1.1	0.2	0.0	5.9	0.9	0.0	1.1	1.6	4.6	6.2	0.0	4.0	0.2	0.1	0.0	0.0	1.9	835.6	0.7	0.0	0.6	0.1	13.8	0.7	0.0	4.0	0.5	0.0	0.0	0.0	0.6	5.4	0.1	1.3	0.5	3141.0	2.3	0.3	0.0	2.7	1.5	2.7	1.0	1.5	1.8	1.3	0.1	0.1	0.0	0.1	1.9	1.2	1.2	0.2	1.0	0.4	0.1	0.0	22.2	0.0	0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.3	0.1	0.1	0.1	0.0	0.0	0.1	0.1	0.0	0.2	0.1	0.0	0.0	0.0	1.0	2.8	2.1	52.1	3.4	0.0	0.1	0.0	0.7	193.0	13.5	0.0	0.0	0.3	0.0	201.0	0.0	31.5	0.7	2.9	0.1	0.2	3.5	2.7	0.0	27.5	0.1	4.4	542.3	1.0	0.0	0.0	2.2	62.9	0.0	0.0	0.1	29.5	4.1	0.6	0.3	0.7	3.4	0.3	0.0	0.0	0.6	0.0	0.0	0.0	0.0	66.9	42.5	1.9	1.7	1.0	327.1	3.8	4.8	0.0	0.0	3.7	1.5	0.0	0.1	96.0	10.4	0.3	0.5	0.0	73.0	11.4
AKR1B15		ENSG00000227471	"Aldo-keto reductase family 1 member B15"	C9JRZ8	7	134549110-134579875	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	9	"breast: 166.7"	"Cell type enhanced"	"Detected in some"		"Early spermatids: 2.2;Fibroblasts: 2.9;Late spermatids: 3.6;Skeletal myocytes: 12.5;Syncytiotrophoblasts: 10.4"	"Cancer enhanced"	"Detected in many"		"head and neck cancer: 5.1"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"A549: 15.8;HDLM-2: 12.8;Hep G2: 11.2;SK-BR-3: 5.1;U-87 MG: 6.7"									"HPA020280, HPA073633"	Uncertain		Supported	"Plasma membrane,Cytosol"		NA	NA				"Cluster 5: Breast - Unknown function"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 50: Fibroblasts - ECM organization"	Cytosol	"Plasma membrane"	"HPA020280: AB_10602228, HPA073633: AB_2686620"	"unprognostic (2.35e-1)"	"unprognostic (3.85e-2)"	"unprognostic (9.74e-3)"	"unprognostic (2.74e-2)"	"unprognostic (2.08e-1)"	"prognostic favorable (8.36e-4)"	"prognostic unfavorable (1.80e-5)"	"unprognostic (5.04e-2)"	"unprognostic (2.39e-1)"	"unprognostic (2.75e-1)"	"unprognostic (2.14e-3)"	"unprognostic (1.24e-1)"	"unprognostic (1.22e-7)"	"unprognostic (6.88e-2)"	"unprognostic (4.29e-1)"	"unprognostic (2.99e-3)"	"prognostic unfavorable (1.90e-5)"	0.4	0.1	0.4	0.2	1.4	0.0	166.7	0.3	0.5	1.1	0.0	0.8	14.0	0.0	0.2	3.2	0.0	5.2	0.1	0.4	1.1	0.1	2.1	0.0	0.0	0.6	1.1	0.0	0.0	0.0	0.0	0.8	0.6	0.3	0.6	0.3	1.8	0.0	7.8	1.1	4.5	0.0	0.7	0.0	12.0	0.5	1.4	0.2	0.1	18.8	0.3	0.9	2.6	1.5	0.1	15.8	0.1	0.0	0.6	0.5	0.9	0.0	0.4	0.0	0.0	0.1	0.2	0.1	0.0	0.0	0.7	0.1	0.0	0.1	0.0	12.8	0.0	0.1	0.2	11.2	0.0	0.2	0.5	0.0	0.2	0.0	0.1	0.1	0.0	0.1	0.2	0.5	0.0	0.0	0.2	0.2	3.1	0.4	0.0	0.1	0.2	0.3	0.1	0.1	0.1	0.1	0.6	5.1	0.0	0.1	0.0	0.3	0.0	0.1	0.7	0.3	0.0	0.2	0.2	0.2	6.7	0.2	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	1.4	0.3	0.5	0.4	1.1	0.6	1.1	0.6	0.7	1.4	1.5	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.1	0.0	0.1	0.0	0.8	0.0	0.0	0.5	0.0	0.0	0.0	0.0	2.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.2	2.9	0.0	0.0	0.0	0.9	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.4	3.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	12.5	0.1	0.0	0.7	0.0	0.3	10.4	0.1	0.0	0.0	0.1
AKR1C1	"DD1, DDH, DDH1, HAKRC, MBAB"	ENSG00000187134	"Aldo-keto reductase family 1 member C1"	Q04828	10	4963253-4983283	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 623.2"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 253.8;Basal squamous epithelial cells: 262.4;Cholangiocytes: 284.5;Exocrine glandular cells: 328.0;Hepatocytes: 597.7;Squamous epithelial cells: 229.3;Urothelial cells: 306.0"	"Cancer enhanced"	"Detected in many"		"liver cancer: 64.2;lung cancer: 53.5"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"basophil: 1.5"	"Low lineage specificity"	"Detected in single"			"Group enriched"	"Detected in many"	8	"ASC diff: 2988.3;Hep G2: 5415.7;OE19: 2297.1"									"CAB047303, HPA068265"	Enhanced		Enhanced	"Endoplasmic reticulum,Cytosol"		NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 2: Hepatocytes - Metabolism"	"Endoplasmic reticulum, Cytosol"		"CAB047303: , HPA068265: AB_2685966"	"unprognostic (1.54e-2)"	"prognostic favorable (3.05e-4)"	"unprognostic (4.04e-2)"	"unprognostic (8.38e-2)"	"unprognostic (3.18e-2)"	"unprognostic (7.05e-2)"	"prognostic unfavorable (1.56e-4)"	"unprognostic (1.70e-1)"	"unprognostic (1.63e-1)"	"unprognostic (8.38e-2)"	"unprognostic (4.65e-1)"	"unprognostic (1.82e-2)"	"prognostic favorable (8.03e-9)"	"unprognostic (1.19e-1)"	"unprognostic (1.22e-1)"	"unprognostic (5.72e-2)"	"unprognostic (6.30e-2)"	185.7	14.3	12.3	13.5	16.5	5.8	116.2	16.0	11.5	12.9	6.9	23.2	25.3	6.6	6.6	103.9	11.5	65.7	135.5	10.9	18.7	45.4	623.2	28.9	4.7	22.1	18.4	15.5	23.3	0.8	9.7	1.7	23.2	17.3	12.2	11.5	73.7	12.5	120.4	35.3	23.4	8.7	19.6	4.1	142.9	13.0	22.2	4.6	46.7	27.3	7.8	71.1	31.3	20.3	0.0	429.6	2.4	426.7	2988.3	358.2	0.2	13.7	95.9	5.4	4.1	8.4	0.5	0.0	6.1	97.7	72.5	3.6	1.6	22.4	2.5	0.1	0.2	12.6	65.6	5415.7	30.0	1.8	0.0	183.9	27.3	44.2	26.7	0.4	10.2	2.9	95.8	0.4	74.7	2.4	0.1	0.4	1.2	2297.1	1.5	0.1	0.8	4.2	24.3	81.4	0.4	1.7	23.8	0.7	0.8	1.3	0.5	7.8	85.3	36.0	2.3	97.6	4.5	1.6	0.5	0.3	129.3	12.1	0.9	1.5	0.0	0.3	0.5	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.1	0.4	0.3	0.1	0.0	0.2	0.1	0.2	12.3	16.5	16.0	11.5	10.9	18.7	22.1	18.4	23.2	19.6	22.2	20.3	21.6	67.3	34.4	2.0	2.4	21.2	27.8	253.8	262.4	3.1	7.6	1.0	3.2	284.5	144.5	62.5	0.0	0.1	0.2	5.9	13.7	67.0	24.0	3.3	1.7	17.1	1.8	52.6	3.4	328.0	0.1	176.3	139.1	4.6	4.5	0.8	21.0	597.7	0.4	0.0	3.1	6.8	20.3	16.1	15.6	9.9	151.6	3.3	106.7	13.1	4.6	51.5	0.0	4.5	0.5	120.2	3.6	147.4	0.4	41.3	20.2	61.9	72.2	4.5	0.0	16.4	24.3	1.9	1.1	229.3	20.5	0.1	2.1	6.4	20.3	306.0
AKR1C2	"BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD"	ENSG00000151632	"Aldo-keto reductase family 1 member C2"	P52895	10	4987400-5018031	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Lipid metabolism, Steroid metabolism"	Oxidoreductase	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 341.5;liver: 481.9"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 141.7;Club cells: 128.8;Gastric mucus-secreting cells: 133.5;Hepatocytes: 397.4;Urothelial cells: 271.9"	"Group enriched"	"Detected in many"	6	"cervical cancer: 21.7;head and neck cancer: 31.5;liver cancer: 50.2;lung cancer: 69.0;urothelial cancer: 35.7"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	5	"A549: 2054.8;ASC diff: 2439.5;Hep G2: 3926.2;OE19: 2684.9;RT4: 1178.9"									"CAB047304, HPA068265"	Enhanced		Approved	"Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol"		NA	NA				"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 2: Hepatocytes - Metabolism"	"Nucleoplasm, Cytosol"	"Nucleoli fibrillar center, Endoplasmic reticulum"	"CAB047304: , HPA068265: AB_2685966"	"unprognostic (6.77e-2)"	"unprognostic (8.88e-3)"	"unprognostic (3.02e-2)"	"unprognostic (2.24e-1)"	"unprognostic (1.31e-1)"	"unprognostic (1.72e-2)"	"unprognostic (2.86e-2)"	"unprognostic (8.65e-2)"	"unprognostic (5.03e-2)"	"unprognostic (2.58e-1)"	"unprognostic (1.02e-1)"	"unprognostic (6.25e-3)"	"unprognostic (8.58e-2)"	"unprognostic (1.09e-2)"	"unprognostic (8.60e-3)"	"unprognostic (1.46e-2)"	"unprognostic (8.30e-2)"	341.5	20.8	9.8	10.0	11.6	1.0	205.6	10.7	12.9	17.4	8.1	37.1	29.6	5.6	3.3	202.5	8.6	98.1	83.8	7.2	16.6	43.0	481.9	23.5	2.1	18.7	13.7	10.4	11.8	1.1	8.1	0.8	17.1	11.7	13.3	15.2	116.5	12.9	286.9	42.5	33.7	9.2	11.5	2.1	137.0	11.8	16.8	4.4	38.3	36.5	9.3	253.9	47.0	9.7	0.0	2054.8	2.4	214.1	2439.5	83.4	0.1	0.7	8.6	0.9	2.0	8.1	0.2	0.4	11.5	14.2	10.0	57.8	0.2	10.7	1.2	0.6	0.2	0.7	516.4	3926.2	4.6	0.4	0.9	218.3	126.4	10.5	10.4	0.7	0.9	0.3	81.9	0.3	20.4	3.3	0.2	0.0	0.7	2684.9	0.8	0.3	0.6	34.6	19.0	1178.9	1.2	0.4	21.2	0.3	0.1	0.4	0.5	4.0	8.6	5.1	1.8	74.6	0.8	0.6	0.6	0.3	25.9	30.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	9.8	11.6	10.7	12.9	7.2	16.6	18.7	13.7	17.1	11.5	16.8	9.7	15.2	12.8	2.8	0.0	0.9	11.9	9.5	141.7	20.5	1.9	0.8	1.4	5.5	102.9	128.8	0.0	0.0	0.0	0.0	10.3	0.0	18.3	17.3	0.7	0.5	7.5	1.8	8.0	2.6	103.3	0.1	44.2	133.5	0.8	0.0	0.1	10.8	397.4	0.1	3.3	4.2	5.4	46.8	12.0	7.8	7.8	79.2	1.0	8.8	19.7	0.6	39.6	0.0	5.5	0.3	90.0	6.6	78.6	0.8	23.7	15.9	3.6	40.3	3.0	0.0	5.3	13.9	0.2	0.3	112.9	13.5	0.0	1.3	0.4	8.5	271.9
AKR1C3	"DDX, HAKRB, HSD17B5, KIAA0119, PGFS"	ENSG00000196139	"Aldo-keto reductase family 1 member C3"	P42330	10	5035354-5107686	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"intestine: 441.3"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 393.1;Exocrine glandular cells: 722.5;Proximal enterocytes: 576.9;Proximal tubular cells: 601.8"	"Cancer enhanced"	"Detected in all"		"liver cancer: 83.8"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"basophil: 244.0;gdT-cell: 102.6"	"Group enriched"	"Detected in many"	4	"granulocytes: 244.0;T-cells: 102.6"	"Cell line enhanced"	"Detected in many"		"A549: 1615.1;ASC diff: 811.9;Hep G2: 699.6;OE19: 3025.3;RT4: 639.2"									"CAB010874, HPA068265"	Enhanced		Approved	"Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol"		NA	NA		19000000	"Cluster 38: Basophils - Unknown function"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 21: OE19 - Mitochondria"	"Cluster 1: Pancreatic cells - Digestion"	"Nucleoplasm, Cytosol"	"Nucleoli fibrillar center, Endoplasmic reticulum"	"CAB010874: AB_476751, HPA068265: AB_2685966"	"unprognostic (4.20e-3)"	"unprognostic (2.70e-2)"	"unprognostic (8.92e-2)"	"unprognostic (1.53e-1)"	"unprognostic (1.05e-1)"	"unprognostic (1.81e-3)"	"prognostic unfavorable (1.96e-4)"	"unprognostic (1.41e-1)"	"unprognostic (6.74e-2)"	"unprognostic (5.08e-2)"	"unprognostic (1.31e-1)"	"unprognostic (4.33e-2)"	"prognostic unfavorable (1.22e-4)"	"unprognostic (4.45e-1)"	"unprognostic (3.70e-2)"	"unprognostic (1.79e-3)"	"unprognostic (4.24e-3)"	164.4	50.2	31.1	25.4	34.6	42.3	115.2	32.1	42.4	21.9	30.2	185.9	441.3	25.9	4.4	53.2	42.1	261.1	42.9	31.5	35.6	177.7	268.0	48.3	7.6	30.3	33.9	17.8	36.4	22.5	10.4	4.7	32.3	10.3	98.0	19.1	40.5	19.4	116.9	27.0	270.9	39.2	30.3	3.8	237.4	10.0	31.5	37.4	26.4	34.8	6.6	84.7	22.2	31.1	0.1	1615.1	1.1	413.0	811.9	292.2	1.0	0.0	21.4	0.4	1.4	47.6	24.5	0.2	78.7	19.4	45.0	11.5	1.5	28.8	1.1	3.0	0.5	3.2	438.4	699.6	4.3	0.7	0.2	160.9	57.1	20.0	0.7	25.8	28.1	3.4	10.8	0.0	42.6	3.8	9.8	2.6	0.7	3025.3	4.3	3.3	9.6	43.7	149.0	639.2	1.0	2.9	232.2	0.0	0.3	0.9	0.5	0.2	221.7	5.2	4.7	87.8	3.1	0.7	0.7	0.3	45.8	62.8	4.4	244.0	2.9	4.8	102.6	0.9	6.9	0.0	19.0	18.7	2.1	0.5	11.6	8.9	7.3	21.1	1.4	39.6	21.4	42.4	31.1	34.6	32.1	42.4	31.5	35.6	30.3	33.9	32.3	30.3	31.5	31.1	144.2	44.8	5.3	4.9	4.3	12.0	3.7	393.1	2.8	2.0	15.8	5.5	3.9	0.0	172.9	36.8	0.0	0.4	64.4	133.8	43.0	114.6	3.3	67.5	4.5	67.5	19.2	34.9	2.5	722.5	0.0	44.3	158.0	66.4	5.7	0.1	0.0	0.0	1.6	1.7	3.2	65.9	61.1	0.0	14.0	4.9	78.3	14.8	21.4	7.5	4.1	132.7	202.9	14.6	0.0	266.1	219.6	106.8	3.1	1.3	576.9	601.8	112.8	5.3	26.3	15.5	20.3	0.5	4.3	20.2	10.7	0.0	14.4	7.8	196.9	46.4
AKR1C4	"3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581"	ENSG00000198610	"Aldo-keto reductase family 1 member C4"	P17516	10	5195462-5218949	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	17	"liver: 717.5"	"Cell type enriched"	"Detected in some"	16	"Hepatocytes: 613.3"	"Cancer enriched"	"Detected in some"	86	"liver cancer: 108.4"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	4	"HDLM-2: 6.6;OE19: 2.9"									"HPA044720, HPA068265"	Uncertain		Approved	"Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol"		NA	NA		3800000		"Cluster 60: Liver - Hemostasis & Lipid metabolism"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 2: Hepatocytes - Metabolism"	"Nucleoplasm, Cytosol"	"Nucleoli fibrillar center, Endoplasmic reticulum"	"HPA044720: AB_2679058, HPA068265: AB_2685966"	"unprognostic (2.21e-1)"	"unprognostic (3.04e-1)"	"unprognostic (5.15e-2)"	"unprognostic (1.25e-1)"		"unprognostic (5.99e-2)"	"unprognostic (9.40e-2)"	"unprognostic (2.32e-1)"		"unprognostic (1.26e-1)"	"unprognostic (1.52e-2)"		"unprognostic (1.29e-1)"	"unprognostic (3.31e-1)"	"unprognostic (7.34e-2)"		"unprognostic (1.45e-2)"	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	2.5	0.0	0.2	0.0	0.4	41.8	0.0	0.0	0.0	0.3	717.5	0.0	0.0	0.1	0.1	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	0.1	1.1	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.8	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.6	0.0	0.3	0.2	1.1	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	2.9	0.0	0.0	0.4	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	37.1	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.2	7.2	0.2	0.0	0.8	0.0	13.5	0.0	0.7	0.0	0.7	0.0	0.0	0.0	0.0	13.6	613.3	0.0	0.0	0.0	0.6	0.0	14.5	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.4	0.1	0.0	0.2	1.0	1.5	0.0	0.0	0.1	0.0	2.1	0.4	0.0	0.0	0.0	0.8	0.0	0.0	0.1
AKR1D1	SRD5B1	ENSG00000122787	"Aldo-keto reductase family 1 member D1"	P51857	7	138002324-138118305	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism"	Oxidoreductase	"Disease variant, FDA approved drug targets, Intrahepatic cholestasis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	83	"liver: 426.9"	"Group enriched"	"Detected in some"	31	"Early spermatids: 65.4;Hepatocytes: 110.3;Late spermatids: 126.1"	"Cancer enriched"	"Detected in single"	77	"liver cancer: 20.1"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in single"	21	"Hep G2: 12.6"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			HPA057002	Enhanced		Approved	Nucleoplasm,Cytosol		No	NA		61000	"Cluster 17: Basophils - Unknown function"	"Cluster 62: Liver - Hemostasis"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 2: Hepatocytes - Metabolism"	Nucleoplasm	Cytosol	"HPA057002: AB_2683308"	"unprognostic (2.38e-1)"	"unprognostic (1.65e-2)"			"unprognostic (1.02e-2)"	"unprognostic (1.52e-2)"	"prognostic favorable (9.91e-5)"	"unprognostic (6.11e-2)"	"unprognostic (2.31e-1)"	"unprognostic (1.30e-1)"	"unprognostic (6.87e-2)"	"unprognostic (2.94e-1)"	"unprognostic (9.68e-3)"	"unprognostic (2.90e-1)"	"unprognostic (5.80e-2)"	"unprognostic (3.11e-1)"	"unprognostic (1.67e-2)"	0.0	0.1	0.2	0.0	0.1	0.2	5.1	0.3	0.3	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.2	0.0	0.1	426.9	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.8	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.4	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.1	12.6	0.0	0.1	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.7	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.6	0.1	0.1	0.1	0.0	0.0	0.2	0.1	0.3	0.3	0.2	0.0	0.2	0.1	0.2	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.2	0.1	0.3	0.0	0.0	0.0	0.1	0.0	0.3	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	65.4	0.0	0.0	0.3	0.0	0.0	0.2	0.0	0.0	0.2	0.0	0.1	0.0	0.0	1.4	110.3	0.4	0.0	0.2	0.2	0.0	3.2	0.4	126.1	0.3	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.4	0.1	0.1	0.0	0.1	0.0	0.0	0.0	0.9	0.1	1.6	0.3	0.0	0.0	0.3	0.3	0.0	0.0	0.2
AKR1E2	"AKR1CL2, AKRDC1, htAKR, HTSP1, MGC10612"	ENSG00000165568	"Aldo-keto reductase family 1 member E2"	Q96JD6	10	4786629-4848062	"Enzymes, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"testis: 19.0"	"Group enriched"	"Detected in some"	5	"Early spermatids: 153.8;Late spermatids: 174.2"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"JURKAT: 12.3;RT4: 10.4;U-2197: 19.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA037821, HPA037822"	Enhanced		Supported	"Nucleoplasm,Golgi apparatus"		NA	NA			"Cluster 10: Basophils - Unknown function"	"Cluster 78: Testis - Spermatogenesis"	"Cluster 18: U-2197 - ECM organization"	"Cluster 34: Spermatids - Unknown function"	"Nucleoplasm, Golgi apparatus"		"HPA037821: AB_2675687, HPA037822: AB_10671722"	"unprognostic (2.33e-2)"	"unprognostic (2.59e-2)"	"unprognostic (1.68e-2)"	"unprognostic (8.27e-2)"	"unprognostic (7.33e-2)"	"unprognostic (1.99e-1)"	"unprognostic (1.44e-1)"	"unprognostic (7.42e-3)"	"unprognostic (7.47e-2)"	"unprognostic (2.77e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.53e-1)"	"unprognostic (3.06e-2)"	"unprognostic (2.74e-1)"	"unprognostic (2.04e-2)"	"unprognostic (1.62e-4)"	"unprognostic (5.62e-2)"	2.0	0.8	1.7	0.7	1.8	2.1	3.1	1.5	2.3	1.8	0.0	1.3	1.4	1.1	0.9	1.4	1.0	1.3	1.9	2.0	2.4	0.9	0.5	2.0	0.8	1.6	2.0	0.7	2.1	1.0	0.5	1.8	2.7	0.9	1.2	3.5	1.1	1.8	1.5	1.2	1.0	2.1	0.5	1.2	1.5	19.0	1.6	0.7	3.3	0.8	0.5	1.1	1.3	1.6	0.5	5.9	2.2	1.0	0.0	0.0	0.1	2.3	0.2	0.1	0.1	9.0	0.8	0.0	0.0	6.0	0.0	0.7	0.2	0.0	0.0	0.0	0.0	0.0	0.2	0.0	2.7	0.0	0.0	1.1	6.2	1.1	0.0	0.0	6.5	12.3	5.6	0.0	0.0	5.4	0.7	0.0	2.2	6.9	4.4	0.0	0.0	0.0	1.6	10.4	0.0	4.8	8.2	2.4	4.7	2.4	4.6	2.6	4.1	0.0	2.0	19.5	0.0	2.8	0.0	0.0	0.1	0.0	1.4	0.9	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.4	0.0	0.3	0.1	0.0	0.0	0.0	0.4	0.0	0.0	1.7	1.8	1.5	2.3	2.0	2.4	1.6	2.0	2.7	0.5	1.6	1.6	0.9	0.0	0.0	1.6	0.2	0.0	0.1	0.5	0.6	0.2	1.1	0.6	0.8	0.0	0.6	1.8	0.0	0.1	0.1	0.0	0.0	0.3	153.8	0.5	0.7	1.4	0.0	1.3	7.1	0.0	0.0	2.2	0.0	0.6	0.0	0.6	2.2	0.0	1.2	1.7	8.9	0.1	0.0	0.6	0.6	174.2	2.8	0.8	3.6	5.6	0.6	0.3	0.0	9.0	0.0	0.1	0.1	1.5	0.0	0.2	0.0	0.5	0.3	1.2	0.0	0.8	1.2	32.0	10.0	0.7	0.1	0.0	0.2	0.2	0.1	0.5
AKR7A2	AFAR	ENSG00000053371	"Aldo-keto reductase family 7 member A2"	O43488	1	19303965-19312144	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Proximal tubular cells: 711.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"											"CAB032587, CAB032841, HPA064638"	Enhanced		Supported	"Golgi apparatus,Cytosol"		NA	NA		950000	"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 35: Non-specific - Unknown function"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Cytosol	"Golgi apparatus"	"CAB032587: AB_673379, CAB032841: AB_2224545, HPA064638: AB_2685307"	"unprognostic (1.06e-1)"	"unprognostic (3.48e-2)"	"unprognostic (7.23e-2)"	"unprognostic (5.76e-2)"	"unprognostic (9.92e-2)"	"unprognostic (1.09e-1)"	"unprognostic (1.14e-2)"	"unprognostic (3.14e-3)"	"unprognostic (1.99e-1)"	"unprognostic (2.50e-2)"	"unprognostic (5.11e-2)"	"unprognostic (7.11e-2)"	"prognostic favorable (2.67e-4)"	"unprognostic (3.72e-2)"	"unprognostic (8.53e-2)"	"unprognostic (1.01e-1)"	"prognostic unfavorable (8.59e-4)"	33.3	67.9	45.3	17.5	48.0	25.0	33.8	47.4	44.2	57.2	66.2	46.4	81.1	34.7	22.4	47.8	48.4	29.1	39.1	45.9	46.1	76.7	62.7	24.6	25.3	48.8	49.4	45.7	47.9	32.7	32.6	19.0	44.9	31.6	27.5	16.0	31.4	27.7	55.4	37.1	56.8	22.6	49.2	28.3	42.7	33.1	48.2	31.3	28.6	39.6	20.5	29.6	38.5	54.1	65.3	40.2	43.3	40.2	67.0	64.7	28.8	47.6	57.6	65.0	58.2	51.5	53.6	46.8	49.6	64.2	36.6	50.8	48.7	71.5	30.5	37.5	77.4	29.4	37.5	83.3	51.9	32.9	22.9	64.8	55.5	50.0	30.6	61.5	55.8	60.2	43.6	42.6	67.7	64.9	64.2	31.9	12.4	90.8	50.1	66.7	54.0	83.2	64.2	28.3	80.9	30.2	51.8	46.1	84.6	24.6	91.9	112.7	44.2	40.6	42.7	44.0	36.2	51.4	34.8	57.9	87.6	74.4	58.5	0.7	82.2	40.6	61.4	69.7	71.7	63.8	54.4	54.2	113.5	57.6	61.7	54.1	9.5	69.4	54.1	98.8	78.9	73.7	45.3	48.0	47.4	44.2	45.9	46.1	48.8	49.4	44.9	49.2	48.2	54.1	47.6	16.0	22.3	15.3	42.6	24.3	73.2	56.4	37.5	33.1	94.6	98.8	27.7	98.7	31.7	77.3	6.2	167.5	52.8	95.0	254.3	64.0	94.6	85.8	35.8	35.3	99.7	33.4	8.6	36.2	99.8	67.9	44.9	33.4	10.2	62.5	43.2	90.6	104.6	21.9	7.5	97.9	46.8	58.4	34.2	57.6	77.3	47.6	53.4	5.6	64.6	128.7	63.8	5.5	9.2	39.4	131.5	67.7	36.3	39.3	273.8	711.5	61.0	30.1	46.0	57.8	54.4	56.3	24.9	76.0	34.1	102.6	40.4	88.4	136.4	62.3
ALDH18A1	"GSAS, P5CS, PYCS, SPG9"	ENSG00000059573	"Aldehyde dehydrogenase 18 family member A1"	P54886	10	95605941-95656711	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Amino-acid biosynthesis, Proline biosynthesis"	"Kinase, Multifunctional enzyme, Oxidoreductase, Transferase"	"Disease variant, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"salivary gland: 120.1"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 80.5;Granulosa cells: 81.6;Proximal enterocytes: 79.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA008333, HPA012604"	Approved		Enhanced	Mitochondria		NA	NA		48000	"Cluster 16: MAIT-cells - Unknown function"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 40: Granulosa cells - Unknown function"	Mitochondria		"HPA008333: AB_1078125, HPA012604: AB_1844721"	"unprognostic (5.97e-3)"	"unprognostic (2.08e-2)"	"unprognostic (5.75e-2)"	"prognostic favorable (4.20e-4)"	"unprognostic (1.60e-2)"	"unprognostic (1.06e-1)"	"unprognostic (8.30e-3)"	"unprognostic (7.08e-2)"	"unprognostic (4.06e-2)"	"unprognostic (8.04e-2)"	"unprognostic (1.30e-1)"	"unprognostic (1.81e-1)"	"prognostic unfavorable (3.60e-9)"	"unprognostic (1.02e-3)"	"unprognostic (6.57e-2)"	"unprognostic (1.29e-3)"	"unprognostic (6.43e-2)"	15.3	16.1	12.2	21.2	12.6	16.7	20.2	12.4	13.1	33.4	21.0	51.9	89.3	18.5	30.9	21.0	21.9	25.2	11.5	12.2	13.6	17.7	24.3	10.8	22.0	12.4	14.7	16.7	61.8	33.5	28.2	26.3	13.1	24.2	49.3	11.4	120.1	24.9	4.3	22.4	73.1	26.3	12.7	12.1	40.5	11.7	14.0	17.2	37.5	5.5	26.9	25.2	14.3	13.1	66.5	61.6	57.9	152.7	76.0	72.9	62.2	75.6	112.8	75.1	93.7	124.4	51.6	223.7	68.9	119.7	36.2	85.6	117.1	77.8	84.6	64.0	92.0	71.2	40.5	177.9	49.7	125.6	76.1	77.0	46.8	61.5	119.1	124.5	79.9	82.6	67.5	46.0	57.1	95.0	114.5	80.5	68.6	109.2	60.7	105.9	66.3	76.9	88.3	49.7	57.5	56.9	60.1	47.1	56.9	66.0	70.5	57.9	66.7	31.1	49.0	80.9	88.2	52.4	41.7	135.8	60.4	142.8	40.7	0.1	2.6	0.2	27.3	5.2	28.7	23.0	24.5	28.3	9.6	16.1	20.7	23.1	0.5	26.3	8.3	5.9	25.8	15.5	12.2	12.6	12.4	13.1	12.2	13.6	12.4	14.7	13.1	12.7	14.0	13.1	4.6	6.4	9.2	7.2	12.6	11.2	8.3	8.9	14.2	6.3	15.6	12.4	4.6	11.5	14.3	20.2	0.0	43.9	6.7	80.5	1.9	13.7	1.3	12.7	18.1	8.0	19.8	17.9	15.7	21.1	31.6	16.2	18.8	16.9	8.2	81.6	5.3	27.3	11.5	10.1	13.6	41.3	8.2	3.5	3.8	1.6	9.3	3.5	16.0	11.2	2.6	7.1	8.2	17.6	12.8	11.7	56.4	12.0	30.1	18.4	79.4	8.4	15.2	3.4	0.0	10.5	10.1	8.2	9.9	17.6	8.1	30.2	9.0	10.8	38.7	9.4
ALDH1A1	"ALDH1, PUMB1, RALDH1"	ENSG00000165092	"Aldehyde dehydrogenase 1 family member A1"	P00352	9	72900671-73080442	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 1500.8"	"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 389.4;Hepatocytes: 624.4;Leydig cells: 406.4;Proximal tubular cells: 375.4;Respiratory ciliated cells: 583.7"	"Cancer enhanced"	"Detected in all"		"liver cancer: 399.1"	"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in many"	6	"classical monocyte: 87.3"	"Lineage enriched"	"Detected in many"	33	"monocytes: 87.3"	"Cell line enhanced"	"Detected in many"		"A549: 4019.8;Hep G2: 1269.3;RPTEC TERT1: 710.6"	"Low region specificity"	"Detected in all"			"Region enriched"	"Detected in all"	6	"midbrain: 378.3"	"HPA002123, CAB020690"	Enhanced	Approved	Enhanced	Cytosol		NA	NA		58000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 85: Liver - Metabolism"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 2: Hepatocytes - Metabolism"	Cytosol		"CAB020690: , HPA002123: AB_1844722"	"unprognostic (8.46e-3)"	"prognostic favorable (7.77e-5)"	"unprognostic (5.59e-2)"	"unprognostic (1.69e-1)"	"unprognostic (1.49e-2)"	"unprognostic (8.71e-2)"	"unprognostic (3.64e-2)"	"unprognostic (3.98e-2)"	"unprognostic (4.53e-2)"	"unprognostic (6.83e-2)"	"unprognostic (4.45e-2)"	"unprognostic (3.73e-1)"	"unprognostic (3.24e-3)"	"unprognostic (2.20e-1)"	"unprognostic (2.36e-1)"	"unprognostic (2.96e-2)"	"unprognostic (1.90e-3)"	109.4	182.4	51.3	28.4	71.9	31.8	64.3	125.1	72.4	121.8	35.7	218.2	549.7	139.3	583.4	41.3	184.3	175.4	53.7	64.6	62.1	335.4	1500.8	142.6	31.2	93.4	370.7	222.7	498.1	24.3	164.4	32.0	84.7	57.2	88.8	0.4	104.5	245.4	66.7	17.2	304.3	117.0	104.2	77.5	568.5	149.5	74.5	19.8	211.7	83.0	21.6	31.6	90.7	106.1	0.0	4019.8	0.4	0.0	22.4	0.2	1.4	139.6	0.0	0.1	0.1	136.2	0.0	0.1	50.5	0.0	0.3	2.6	0.0	0.2	0.1	0.4	0.1	232.1	0.6	1269.3	13.7	0.6	0.3	6.7	0.1	0.0	0.0	0.3	143.0	0.0	16.9	0.0	153.3	7.2	0.2	1.8	0.7	7.2	0.4	0.5	44.0	1.8	710.6	1.1	0.3	1.4	0.3	0.4	2.9	0.2	0.0	0.5	0.7	0.0	3.5	0.5	0.3	0.4	0.2	1.0	0.0	1.7	0.4	0.0	87.3	1.4	0.0	14.9	0.0	0.0	0.2	0.1	1.4	0.7	0.0	0.0	2.6	0.0	1.1	1.0	0.0	30.3	51.3	71.9	125.1	72.4	64.6	62.1	93.4	370.7	84.7	104.2	74.5	106.1	4.9	96.1	107.6	31.3	6.9	2.7	18.3	168.3	1.2	0.4	12.6	1.7	4.3	187.3	361.1	115.8	0.0	1.7	0.1	20.2	389.4	71.6	12.6	6.3	125.2	26.4	54.9	96.1	3.5	349.7	1.0	102.7	258.4	8.1	158.9	0.2	133.5	624.4	134.4	0.0	0.5	168.9	138.4	109.6	5.1	37.8	406.4	61.7	7.2	17.8	46.0	0.0	2.1	0.0	0.7	128.4	77.4	207.3	1.3	2.0	267.4	375.4	583.7	0.3	26.3	334.2	28.6	8.6	4.6	21.5	3.1	2.5	8.8	129.6	131.7	26.5
ALDH1A2	RALDH2	ENSG00000128918	"Aldehyde dehydrogenase 1 family member A2"	O94788	15	57953424-58497866	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"endometrium 1: 82.2;fallopian tube: 74.5"	"Group enriched"	"Detected in many"	4	"Early spermatids: 115.7;Endometrial stromal cells: 142.2;Late spermatids: 48.7;Microglial cells: 42.2;Spermatocytes: 78.9"	"Low cancer specificity"	"Detected in many"			"Group enriched"	"Detected in many"	4	"cerebral cortex: 13.1;hippocampal formation: 8.4"	"Immune cell enriched"	"Detected in some"	15	"neutrophil: 32.6"	"Lineage enriched"	"Detected in single"	62	"granulocytes: 32.6"	"Group enriched"	"Detected in some"	5	"AN3-CA: 402.4;HEK 293: 128.8;JURKAT: 387.2;K-562: 316.2;MOLT-4: 408.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			HPA010022	Approved					NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 36: Stromal cells - Cell proliferation"			"HPA010022: AB_1844723"	"unprognostic (1.11e-2)"	"unprognostic (2.52e-2)"	"unprognostic (2.00e-1)"	"unprognostic (3.09e-1)"	"unprognostic (1.44e-2)"	"unprognostic (1.16e-2)"	"unprognostic (1.04e-4)"	"unprognostic (1.08e-1)"	"unprognostic (9.03e-3)"	"unprognostic (6.92e-3)"	"unprognostic (5.48e-2)"	"unprognostic (6.19e-2)"	"unprognostic (2.57e-3)"	"unprognostic (3.18e-2)"	"unprognostic (4.95e-2)"	"unprognostic (1.99e-2)"	"unprognostic (1.80e-3)"	21.3	3.9	1.9	2.9	1.4	4.0	5.9	2.1	13.1	52.3	3.4	1.7	0.7	82.2	7.8	2.4	74.5	24.0	28.4	8.4	0.9	19.5	2.6	7.8	0.6	1.7	1.6	24.0	3.2	29.8	14.6	5.2	1.9	21.0	0.7	6.0	2.0	53.3	10.7	1.7	1.3	31.9	1.8	4.3	0.7	57.6	2.5	2.8	1.4	3.0	0.4	4.0	12.9	1.1	1.2	0.0	0.0	402.4	0.0	0.0	0.1	0.0	5.7	0.6	1.3	0.0	0.3	0.4	3.9	0.0	0.1	1.0	11.8	0.0	0.7	0.0	128.8	0.0	2.7	0.7	0.3	0.0	3.0	2.3	0.0	0.0	0.0	0.0	21.4	387.2	316.2	0.0	0.0	0.0	408.5	0.1	0.7	11.2	19.6	0.0	0.8	0.0	70.7	2.0	0.8	0.1	0.4	0.4	1.9	0.4	0.2	0.1	0.9	0.3	1.0	3.8	0.0	0.3	0.0	0.0	0.2	0.2	0.1	2.1	0.5	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	32.6	0.0	0.3	0.0	0.0	0.0	1.9	1.4	2.1	13.1	8.4	0.9	1.7	1.6	1.9	1.8	2.5	1.1	13.1	6.4	13.9	0.0	0.0	0.6	1.9	0.2	0.0	1.1	1.1	0.9	2.4	20.0	3.4	7.3	0.0	0.3	0.1	5.2	13.7	11.6	115.7	6.8	142.2	7.6	0.0	0.0	5.8	0.4	0.3	17.6	0.0	3.6	1.3	0.3	10.8	17.4	2.2	0.0	9.6	0.1	0.0	1.6	0.8	48.7	5.3	3.0	1.8	42.2	0.7	10.1	0.0	0.0	1.2	0.7	0.3	5.3	0.0	1.3	0.3	0.3	1.4	0.3	0.0	8.3	3.3	78.9	14.7	0.2	0.4	0.5	1.0	0.1	0.7	1.3
ALDH1A3	"ALDH6, RALDH3"	ENSG00000184254	"Aldehyde dehydrogenase 1 family member A3"	P47895	15	100877714-100916626	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, Microphthalmia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"prostate: 134.5;urinary bladder: 125.1"	"Cell type enhanced"	"Detected in many"		"Basal prostatic cells: 175.4;Endometrial stromal cells: 247.9;Leydig cells: 194.5;Prostatic glandular cells: 580.3;Urothelial cells: 468.7"	"Cancer enriched"	"Detected in many"	5	"prostate cancer: 80.5"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"A-431: 363.3;HaCaT: 441.7;HBEC3-KT: 1096.9;hTERT-RPE1: 347.7;U-2197: 619.0;U-87 MG: 484.7;WM-115: 516.1"	"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in many"	4	"olfactory bulb: 4.5;spinal cord: 15.8"	"HPA046271, HPA064749"	Enhanced		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 2: Granulocytes - Unknown function"	"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 22: Epithelial cell types - Mixed function"	Nucleoplasm	Cytosol	"HPA046271: AB_10965992, HPA064749: AB_2685344"	"unprognostic (6.87e-2)"	"unprognostic (2.23e-1)"	"unprognostic (6.20e-3)"	"unprognostic (1.21e-3)"	"unprognostic (1.76e-2)"	"unprognostic (1.14e-1)"	"unprognostic (6.28e-2)"	"unprognostic (5.46e-2)"	"unprognostic (9.62e-2)"	"unprognostic (4.53e-2)"	"unprognostic (3.64e-2)"	"unprognostic (2.56e-1)"	"unprognostic (1.25e-2)"	"unprognostic (2.61e-2)"	"unprognostic (2.12e-1)"	"unprognostic (7.34e-2)"	"unprognostic (6.07e-3)"	83.7	11.4	3.0	41.5	2.7	0.6	30.5	4.7	5.2	37.1	16.2	16.6	15.0	8.2	30.3	28.7	24.9	17.0	12.4	3.1	1.9	8.2	5.3	9.8	3.0	4.8	3.4	6.1	15.0	9.0	7.5	8.4	2.6	134.5	8.9	0.3	93.7	49.3	5.9	3.9	25.2	40.8	2.8	3.1	12.8	16.6	3.3	1.6	2.5	6.9	15.7	125.1	22.3	3.9	363.3	43.5	0.6	0.7	75.0	32.8	1.4	3.2	3.2	1.9	0.8	1.0	285.8	2.6	4.7	97.1	55.7	441.7	8.8	1096.9	6.7	0.1	2.0	1.7	20.1	0.3	25.5	1.4	1.9	23.5	29.8	24.4	4.5	347.7	4.0	0.0	0.7	2.4	1.8	3.8	0.2	1.2	9.0	9.6	316.3	0.7	4.2	2.3	0.2	283.6	0.3	25.4	113.9	94.9	33.3	3.6	9.3	3.2	58.3	0.3	1.0	619.0	14.2	0.7	3.4	1.5	484.7	0.2	516.1	0.3	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	3.0	2.7	4.7	5.2	3.1	1.9	4.8	3.4	2.6	2.8	3.3	3.9	10.0	16.0	6.3	0.3	0.5	0.6	175.4	70.5	4.6	0.0	64.6	18.9	2.0	1.5	141.6	103.0	0.0	9.6	0.9	1.0	3.9	70.5	1.2	20.6	247.9	11.6	3.5	0.0	2.9	1.4	0.5	48.9	1.1	11.7	5.7	0.0	1.8	0.1	1.2	0.0	2.3	2.1	30.5	0.0	1.3	8.5	194.5	3.3	0.0	1.0	0.6	0.0	0.0	36.7	4.6	29.4	0.0	135.4	0.0	580.3	0.1	0.7	78.7	0.0	13.1	20.4	11.5	0.5	0.9	2.9	1.6	4.9	2.0	1.5	0.8	468.7
ALDH1B1	"ALDH5, ALDHX"	ENSG00000137124	"Aldehyde dehydrogenase 1 family member B1"	P30837	9	38392702-38398661	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 172.7;smooth muscle: 128.0"	"Cell type enhanced"	"Detected in many"		"Cholangiocytes: 85.8;Ductal cells: 64.1;Hepatocytes: 128.1;Proximal tubular cells: 165.0;Theca cells: 91.7;Undifferentiated cells: 71.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"OE19: 183.3"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA021037, HPA077080"	Enhanced		Supported	Nucleoplasm,Mitochondria,Cytosol		NA	NA		500000	"Cluster 27: Non-specific - Gene expression"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria	"Nucleoplasm, Cytosol"	"HPA021037: AB_1844724, HPA077080: "	"unprognostic (4.16e-1)"	"unprognostic (1.98e-2)"	"unprognostic (5.84e-2)"	"unprognostic (1.55e-3)"	"unprognostic (2.47e-2)"	"unprognostic (4.48e-3)"	"unprognostic (2.84e-3)"	"unprognostic (2.70e-2)"	"unprognostic (1.91e-1)"	"unprognostic (1.35e-1)"	"unprognostic (2.09e-1)"	"unprognostic (1.00e-1)"	"prognostic favorable (2.05e-4)"	"unprognostic (1.04e-1)"	"unprognostic (1.63e-1)"	"prognostic unfavorable (1.17e-5)"	"unprognostic (2.89e-2)"	21.2	10.4	3.2	31.4	3.2	2.9	8.9	4.1	4.0	8.5	6.4	61.5	22.9	57.7	5.7	32.7	34.9	29.0	14.7	2.7	4.8	59.2	172.7	7.3	5.1	3.5	3.3	12.6	11.3	8.5	2.5	5.2	4.3	36.9	35.5	1.5	11.1	54.5	55.8	6.3	24.8	128.0	3.4	7.2	28.2	8.3	4.0	5.1	15.4	35.9	5.6	85.1	10.5	4.1	72.2	65.5	19.8	31.8	27.6	32.5	15.8	33.6	16.9	27.8	28.3	44.2	13.7	45.2	19.7	47.4	42.0	10.0	66.0	71.4	27.4	50.8	28.5	22.4	44.7	132.2	20.0	36.0	24.0	39.0	15.3	22.6	19.5	56.6	26.8	10.6	65.6	42.8	42.8	27.3	0.1	14.4	59.1	183.3	29.0	14.9	119.9	34.5	25.1	31.7	43.3	19.9	25.7	16.7	19.4	20.6	15.9	27.9	18.2	31.9	52.4	26.9	42.5	6.5	13.2	17.8	16.4	36.0	22.1	0.3	4.2	0.2	6.7	9.2	9.6	5.5	6.5	6.1	9.5	2.6	5.1	6.2	1.0	8.0	11.9	1.2	5.0	5.3	3.2	3.2	4.1	4.0	2.7	4.8	3.5	3.3	4.3	3.4	4.0	4.1	3.3	9.6	1.7	0.0	3.7	1.0	5.7	9.4	2.2	1.2	3.7	4.2	6.6	85.8	3.8	16.5	2.1	2.0	1.2	12.8	17.6	64.1	0.6	2.3	6.4	4.7	15.6	12.8	0.5	6.9	46.6	6.6	8.2	3.4	8.9	12.8	8.9	128.1	7.2	0.0	1.1	25.5	6.1	4.1	2.4	2.2	6.5	4.2	0.0	0.0	5.5	2.1	0.0	0.5	0.5	15.0	7.7	6.8	3.7	6.1	10.3	165.0	0.3	0.7	0.0	6.0	16.1	0.6	0.8	2.1	1.0	1.8	3.3	91.7	71.7	2.8
ALDH1L1	"10-fTHF, FDH, FTHFD"	ENSG00000144908	"Aldehyde dehydrogenase 1 family member L1"	O75891	3	126103562-126197994	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"One-carbon metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 369.7"	"Group enriched"	"Detected in many"	4	"Hepatocytes: 633.3;Proximal tubular cells: 197.4"	"Cancer enriched"	"Detected in many"	4	"liver cancer: 40.4"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"ASC diff: 36.5;Hep G2: 78.1;Karpas-707: 82.0;RPMI-8226: 45.0;RT4: 219.1;U-266/70: 44.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA036900, HPA050139"	Enhanced	Supported	Supported	Cytosol		No	No		3000000		"Cluster 15: Liver - Metabolism"	"Cluster 15: RT4 - Unknown function"	"Cluster 2: Hepatocytes - Metabolism"	Cytosol		"HPA036900: AB_10672273, HPA050139: AB_2681031"	"unprognostic (5.93e-2)"	"unprognostic (1.22e-1)"	"unprognostic (9.12e-2)"	"unprognostic (2.68e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.10e-1)"	"unprognostic (7.12e-2)"	"unprognostic (1.29e-1)"	"unprognostic (3.05e-2)"	"unprognostic (4.73e-2)"	"unprognostic (3.05e-3)"	"unprognostic (8.40e-2)"	"prognostic favorable (2.42e-8)"	"unprognostic (3.60e-1)"	"unprognostic (1.47e-1)"	"unprognostic (7.03e-3)"	"unprognostic (7.93e-2)"	76.4	37.2	53.4	2.0	63.2	0.4	28.8	55.9	63.6	15.6	37.7	10.1	0.2	7.2	2.5	6.6	16.0	2.3	26.5	47.5	56.2	116.6	369.7	3.1	0.3	56.7	52.9	45.3	44.3	15.1	4.5	0.0	53.0	14.6	5.4	8.7	88.6	6.9	90.7	3.5	5.6	2.0	48.4	0.4	9.5	15.0	53.9	3.7	2.6	59.9	4.6	28.3	6.4	46.0	1.3	0.0	0.0	0.0	36.5	0.0	0.4	0.3	1.5	0.4	0.6	0.0	3.2	2.6	10.2	0.0	2.1	0.4	0.6	1.5	0.7	0.0	0.2	0.1	0.3	78.1	10.6	10.6	0.2	0.3	0.8	0.0	0.0	0.3	0.0	0.0	0.0	82.0	1.6	0.0	0.0	0.2	0.3	1.1	0.0	0.1	0.2	45.0	0.7	219.1	0.4	0.3	1.3	10.6	0.0	0.6	0.1	0.0	0.3	1.4	6.2	0.0	0.1	44.8	14.8	0.4	0.2	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	53.4	63.2	55.9	63.6	47.5	56.2	56.7	52.9	53.0	48.4	53.9	46.0	0.8	0.0	6.0	92.7	4.6	0.1	53.5	9.1	1.8	0.2	14.4	2.2	16.1	38.6	44.0	12.9	0.0	0.0	0.1	7.2	72.4	2.9	22.3	57.2	5.2	4.6	1.2	34.7	0.6	5.6	0.2	9.1	0.0	3.6	27.8	12.4	17.2	633.3	0.1	0.0	3.0	17.6	2.0	24.5	1.9	35.0	26.4	9.3	3.6	3.7	0.0	40.0	0.0	11.1	0.2	2.2	0.4	22.6	0.0	12.2	0.8	197.4	32.2	1.4	6.6	10.5	5.3	1.6	4.3	1.7	0.0	0.1	2.8	0.9	5.6	61.7
ALDH1L2	"FLJ38508, mtFDH"	ENSG00000136010	"Aldehyde dehydrogenase 1 family member L2"	Q3SY69	12	105019784-105107643	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"One-carbon metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"pancreas: 40.7;salivary gland: 13.0"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 23.1;Inhibitory neurons: 24.0;Oligodendrocyte precursor cells: 25.1;Plasma cells: 14.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"ASC diff: 62.8;ASC TERT1: 85.2;fHDF/TERT166: 102.4;HHSteC: 55.6;HSkMC: 69.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA039481, HPA059282"	Approved		Enhanced	Mitochondria		No	No				"Cluster 25: Pancreas - Digestion"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 50: Fibroblasts - ECM organization"	Mitochondria		"HPA039481: AB_10795465, HPA059282: AB_2732633"	"unprognostic (5.99e-2)"	"unprognostic (1.42e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.36e-3)"	"unprognostic (1.76e-1)"	"unprognostic (8.86e-2)"	"unprognostic (1.75e-1)"	"unprognostic (2.92e-1)"	"unprognostic (5.74e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.61e-1)"	"unprognostic (8.19e-8)"	"unprognostic (3.21e-3)"	"unprognostic (1.33e-1)"	"unprognostic (2.53e-3)"	"unprognostic (2.52e-5)"	3.7	0.6	1.3	3.1	1.2	0.6	2.3	2.3	1.6	5.3	0.7	2.2	2.6	2.0	1.0	1.3	1.5	2.8	1.9	1.1	1.6	0.4	0.2	1.8	1.0	1.4	1.3	0.6	40.7	0.6	1.3	1.1	1.5	3.6	2.3	0.7	13.0	4.6	0.8	1.0	1.4	4.2	1.8	0.7	3.3	1.1	1.6	0.5	2.1	1.2	1.7	3.4	1.5	2.5	13.0	1.3	0.7	27.3	62.8	85.2	1.6	40.8	26.0	5.2	13.5	1.6	0.0	0.0	1.6	102.4	0.2	0.1	0.1	1.0	6.5	0.0	0.3	0.8	0.1	3.4	55.6	5.3	0.1	69.7	3.1	13.6	25.2	0.0	3.0	0.2	2.1	37.7	10.6	0.0	0.0	0.3	1.6	0.0	0.3	0.0	0.1	4.3	0.0	0.0	9.4	4.5	0.0	8.3	20.5	0.4	6.0	44.0	0.3	3.9	3.8	0.0	2.2	45.5	12.8	0.1	16.2	19.2	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.3	1.2	2.3	1.6	1.1	1.6	1.4	1.3	1.5	1.8	1.6	2.5	1.4	0.0	0.6	3.3	2.6	0.5	0.1	0.7	0.0	1.7	0.3	1.1	1.6	0.0	0.2	0.0	0.0	0.2	1.5	0.1	0.0	0.3	4.1	0.7	8.5	0.9	0.0	0.0	23.1	9.8	0.6	10.5	1.5	1.6	0.0	0.1	1.1	0.0	0.4	5.0	24.0	0.0	0.0	0.6	1.7	5.9	3.7	1.0	5.4	1.0	4.0	1.3	0.0	25.1	8.5	3.7	0.0	6.8	14.6	0.4	0.0	0.1	0.2	0.8	0.0	3.6	8.4	1.7	0.1	0.0	0.6	0.3	0.9	0.1	0.1	0.2
ALDH2		ENSG00000111275	"Aldehyde dehydrogenase 2 family member"	P05091	12	111766887-111817532	"Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 857.7"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 857.0;monocytes: 940.8;Proximal tubular cells: 882.0"	"Cancer enhanced"	"Detected in all"		"liver cancer: 71.5"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"classical monocyte: 212.0;myeloid DC: 213.2"	"Group enriched"	"Detected in many"	4	"dendritic cells: 213.2;monocytes: 212.0"	"Cell line enhanced"	"Detected in many"		"ASC diff: 86.8;HHSteC: 97.0;OE19: 152.2;SK-BR-3: 201.0;THP-1: 92.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA051065	Approved					NA	NA		2200000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 15: Liver - Metabolism"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA051065: AB_2681332"	"unprognostic (9.22e-3)"	"unprognostic (1.20e-2)"	"unprognostic (4.14e-3)"	"prognostic favorable (2.63e-4)"	"unprognostic (1.16e-1)"	"unprognostic (1.32e-3)"	"prognostic favorable (3.95e-7)"	"unprognostic (5.62e-3)"	"unprognostic (3.00e-1)"	"unprognostic (1.16e-1)"	"unprognostic (8.22e-2)"	"unprognostic (1.51e-1)"	"prognostic favorable (5.24e-6)"	"unprognostic (9.70e-2)"	"unprognostic (3.40e-1)"	"unprognostic (1.50e-2)"	"prognostic unfavorable (7.71e-4)"	303.8	102.4	139.7	39.8	146.1	29.2	77.2	136.5	163.5	25.0	123.3	73.3	73.7	30.1	21.3	73.6	32.3	37.4	111.3	132.2	139.7	177.7	857.7	111.6	18.7	140.7	144.9	42.0	23.3	2.6	23.3	7.0	141.1	34.6	72.3	29.2	32.4	29.5	130.8	127.9	74.8	30.2	143.0	20.6	101.5	13.0	151.8	27.1	30.8	165.7	52.9	50.0	29.0	144.5	8.8	13.1	18.7	31.9	86.8	13.0	60.9	9.3	16.8	4.3	3.1	23.5	12.1	0.5	45.3	20.8	11.9	16.2	0.1	4.6	2.7	0.6	6.1	0.7	8.4	64.7	97.0	0.9	0.9	23.9	22.6	14.8	0.3	17.7	26.9	0.9	17.9	3.0	4.1	0.5	1.0	23.4	24.8	152.2	2.1	0.6	0.4	1.9	31.4	0.6	7.5	23.1	22.8	201.0	0.2	33.7	20.3	92.1	1.1	0.4	16.5	0.6	0.4	5.5	3.0	25.7	22.0	0.8	0.4	6.5	212.0	51.1	0.7	93.0	0.9	6.2	0.3	0.7	213.2	5.2	0.7	0.5	10.7	3.4	25.4	70.6	0.5	123.5	139.7	146.1	136.5	163.5	132.2	139.7	140.7	144.9	141.1	143.0	151.8	144.5	27.7	147.4	242.7	51.2	22.6	60.0	205.2	311.1	80.8	78.7	35.0	23.7	378.9	165.8	243.1	66.2	18.8	62.4	48.6	260.3	399.2	127.5	4.3	27.8	24.5	66.2	55.2	42.1	11.7	218.0	127.5	103.1	200.3	47.7	30.9	29.0	139.6	857.0	129.2	35.3	18.2	231.0	101.7	278.5	124.1	10.6	79.9	189.3	35.6	26.2	940.8	130.2	8.2	14.1	6.8	130.2	366.5	149.0	12.5	84.4	384.3	882.0	89.4	42.6	46.0	46.0	67.6	3.0	3.9	105.1	124.7	42.1	13.1	81.0	272.6	150.4
ALDH3A1	ALDH3	ENSG00000108602	"Aldehyde dehydrogenase 3 family member A1"	P30838	17	19737984-19748943	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 496.1;salivary gland: 128.0;stomach 1: 224.8"	"Group enriched"	"Detected in many"	4	"Basal respiratory cells: 389.5;Basal squamous epithelial cells: 274.3;Club cells: 150.1;Gastric mucus-secreting cells: 437.9;Respiratory ciliated cells: 412.7;Squamous epithelial cells: 342.2"	"Cancer enhanced"	"Detected in many"		"head and neck cancer: 64.4;lung cancer: 60.4"	"Low region specificity"	"Detected in some"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	23	"A549: 5094.7;OE19: 6071.6"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"CAB045957, HPA051150, HPA063783"	Enhanced		Supported	"Nucleoplasm,Vesicles,Plasma membrane,Cytosol"		No	No		52000	"Cluster 22: NK-cells - Unknown function"	"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 21: OE19 - Mitochondria"	"Cluster 61: Squamous epithelial cells - Keratinization"	"Plasma membrane, Cytosol"	"Nucleoplasm, Vesicles"	"CAB045957: AB_11127164, HPA051150: AB_2681364, HPA063783: AB_2685122"	"unprognostic (3.11e-5)"	"unprognostic (1.20e-2)"	"unprognostic (1.08e-1)"	"unprognostic (7.04e-3)"	"unprognostic (4.36e-3)"	"prognostic favorable (7.55e-5)"	"unprognostic (3.12e-1)"	"unprognostic (3.84e-1)"	"unprognostic (2.10e-1)"	"unprognostic (1.67e-1)"	"unprognostic (2.69e-3)"	"unprognostic (5.54e-2)"	"unprognostic (1.72e-1)"	"unprognostic (3.84e-2)"	"unprognostic (1.83e-1)"	"unprognostic (2.88e-2)"	"unprognostic (7.23e-2)"	1.7	1.0	0.4	1.3	0.7	0.1	3.2	0.3	0.4	6.7	17.5	4.5	6.2	0.3	0.2	496.1	5.5	10.3	0.3	1.0	0.4	1.3	1.9	10.9	0.5	0.6	2.1	0.4	0.5	0.0	0.9	0.0	0.5	1.9	3.3	0.1	128.0	1.5	1.3	72.6	3.5	0.4	0.9	0.9	224.8	1.6	1.3	0.6	0.5	0.3	33.7	6.2	22.3	0.9	0.1	5094.7	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.1	0.2	10.7	246.5	0.0	2.7	0.5	2.0	29.3	0.7	12.8	0.0	0.0	0.8	0.1	116.6	1.0	0.3	0.1	0.5	0.0	14.9	0.5	0.4	0.2	0.5	0.0	0.0	0.0	0.0	9.7	0.1	0.3	0.4	6071.6	19.8	0.0	0.0	0.0	0.0	87.0	0.2	0.6	24.8	0.0	0.0	0.2	0.2	0.9	0.6	0.3	0.8	0.0	0.0	0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.4	0.0	0.0	0.0	0.0	0.4	0.7	0.3	0.4	1.0	0.4	0.6	2.1	0.5	0.9	1.3	0.9	0.7	3.2	5.5	0.0	0.7	44.1	46.8	389.5	274.3	0.0	0.1	1.5	0.4	2.8	150.1	0.0	0.0	0.0	0.0	5.1	0.0	1.4	1.5	12.4	0.2	1.3	1.8	0.0	0.1	0.5	0.0	1.6	437.9	0.8	2.5	0.3	1.4	3.2	0.2	0.0	0.0	4.8	83.4	0.3	1.8	5.2	0.9	1.0	0.0	0.0	0.0	1.9	0.0	0.0	0.1	9.5	4.7	1.9	3.2	5.8	3.4	5.0	412.7	0.2	0.0	1.7	20.1	1.7	8.6	342.2	32.0	0.0	0.5	0.2	8.4	64.3
ALDH3A2	"ALDH10, FALDH, SLS"	ENSG00000072210	"Aldehyde dehydrogenase 3 family member A2"	P51648	17	19648136-19685760	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase	"Disease variant, Ichthyosis, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 288.6"	"Cell type enhanced"	"Detected in all"		"Basal squamous epithelial cells: 287.4;Squamous epithelial cells: 232.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"OE19: 285.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA014769, CAB020692"	Enhanced		Approved	"Endoplasmic reticulum,Cytosol"		NA	NA		32000	"Cluster 14: Monocytes - Unknown function"	"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 21: OE19 - Mitochondria"	"Cluster 61: Squamous epithelial cells - Keratinization"	"Endoplasmic reticulum, Cytosol"		"CAB020692: , HPA014769: AB_1844728"	"unprognostic (1.42e-1)"	"unprognostic (7.62e-2)"	"unprognostic (7.77e-2)"	"unprognostic (2.49e-2)"	"unprognostic (4.59e-1)"	"unprognostic (1.64e-1)"	"unprognostic (1.59e-1)"	"unprognostic (1.31e-2)"	"unprognostic (2.23e-1)"	"unprognostic (3.93e-3)"	"unprognostic (2.40e-1)"	"unprognostic (2.63e-1)"	"prognostic favorable (3.85e-8)"	"unprognostic (4.12e-2)"	"unprognostic (1.55e-1)"	"unprognostic (1.42e-2)"	"unprognostic (1.26e-1)"	75.2	203.0	23.1	15.2	32.5	9.3	34.9	24.8	27.7	49.4	71.7	49.6	68.1	29.4	41.7	131.3	38.3	70.5	44.6	29.0	27.9	173.0	288.6	59.1	14.9	23.3	26.3	32.3	52.3	40.6	21.9	11.8	23.5	75.0	36.5	40.8	61.7	41.5	53.0	207.6	71.8	30.2	25.1	19.4	81.5	26.9	24.8	23.0	75.1	100.9	36.4	24.2	40.5	33.6	27.7	147.0	29.2	58.5	88.7	89.4	19.1	12.3	29.9	24.4	27.6	63.2	52.5	12.3	35.9	50.5	29.3	99.0	59.8	125.2	19.9	36.2	42.5	5.3	120.9	142.8	12.2	30.6	5.4	42.9	137.6	22.9	12.2	49.7	49.2	25.5	2.2	0.6	37.3	45.3	0.7	25.2	32.3	285.4	78.5	38.6	64.1	25.3	17.5	132.3	46.3	30.4	98.9	38.4	35.3	152.2	78.1	35.0	46.7	10.1	28.7	68.8	45.6	11.3	28.6	15.5	47.4	0.3	48.3	0.8	21.1	17.5	6.3	18.3	9.9	5.2	6.0	6.1	20.7	4.9	6.8	6.3	2.2	15.0	20.6	1.3	11.3	11.0	23.1	32.5	24.8	27.7	29.0	27.9	23.3	26.3	23.5	25.1	24.8	33.6	22.1	176.3	86.5	14.7	13.3	57.1	143.9	85.1	287.4	15.3	13.6	24.0	54.1	105.8	86.5	33.1	12.5	12.5	8.2	48.9	43.0	97.5	79.6	47.5	13.4	19.5	16.2	8.2	30.5	52.0	4.6	39.9	87.7	36.9	29.7	34.6	13.6	116.7	24.6	6.7	20.1	27.7	26.4	21.7	15.1	19.5	55.9	23.5	7.2	13.1	25.7	105.9	8.2	19.6	29.1	43.9	28.7	80.5	28.6	104.2	90.6	119.2	59.2	21.4	13.1	70.1	22.1	15.5	24.0	232.6	90.2	1.4	13.2	29.1	46.0	51.4
ALDH3B1	ALDH7	ENSG00000006534	"Aldehyde dehydrogenase 3 family member B1"	P43353	11	68008578-68029282	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 46.5"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 115.4;Alveolar cells type 2: 58.4;Endometrial ciliated cells: 54.5;Kupffer cells: 59.0;Respiratory ciliated cells: 211.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"eosinophil: 163.2"	"Group enriched"	"Detected in many"	10	"dendritic cells: 67.5;granulocytes: 163.2;monocytes: 125.8"	"Cell line enhanced"	"Detected in many"		"A549: 154.4;CAPAN-2: 154.9;RPMI-8226: 85.9;U-87 MG: 89.1"	"Low region specificity"	"Detected in all"							HPA038525	Uncertain					NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 49: Ciliated cells - Cilium organization"			"HPA038525: AB_2676062"	"unprognostic (3.50e-1)"	"unprognostic (4.22e-1)"	"prognostic unfavorable (1.18e-4)"	"unprognostic (1.56e-2)"	"unprognostic (9.66e-3)"	"unprognostic (9.73e-2)"	"unprognostic (7.93e-3)"	"unprognostic (2.62e-1)"	"unprognostic (2.01e-1)"	"unprognostic (1.06e-1)"	"prognostic unfavorable (6.07e-4)"	"unprognostic (8.27e-2)"	"unprognostic (6.49e-3)"	"unprognostic (1.00e-1)"	"unprognostic (2.75e-2)"	"unprognostic (6.69e-3)"	"unprognostic (1.06e-1)"	12.7	26.7	2.9	10.6	4.5	46.5	5.5	5.1	4.2	11.4	8.9	9.8	23.4	6.4	0.9	13.9	39.6	8.8	4.0	2.5	3.8	16.3	4.1	44.4	5.6	6.0	5.6	3.6	8.0	0.6	7.7	11.7	4.9	4.7	6.5	0.5	11.1	4.1	2.0	5.7	18.0	5.6	4.5	20.0	20.7	2.1	5.4	1.3	2.5	1.7	2.6	10.8	8.9	6.2	11.4	154.4	1.1	3.3	9.9	31.0	26.8	15.1	24.8	10.9	5.3	5.7	154.9	0.7	26.9	35.9	15.3	12.9	0.3	2.1	2.7	0.4	0.9	1.6	64.3	13.4	61.0	9.1	0.5	22.5	6.8	5.4	14.6	24.6	0.6	0.8	0.4	27.3	17.8	9.5	0.9	9.0	1.2	76.1	9.2	3.7	5.9	85.9	17.9	1.5	1.8	0.8	35.7	29.7	15.2	0.8	34.3	19.7	16.2	15.7	21.3	76.2	5.3	0.4	3.0	0.2	89.1	24.5	7.4	47.6	91.0	163.2	0.2	125.8	0.3	0.4	0.2	0.2	67.5	0.5	0.2	0.1	26.6	11.8	118.1	7.0	0.1	47.7	2.9	4.5	5.1	4.2	2.5	3.8	6.0	5.6	4.9	4.5	5.4	6.2	0.4	115.4	58.4	1.0	1.4	2.2	2.7	8.4	1.2	0.5	1.7	1.3	3.1	20.0	53.6	5.5	0.0	0.8	2.9	6.6	0.0	7.4	21.6	54.5	9.2	1.8	2.4	7.8	0.2	2.5	8.2	6.5	12.8	5.1	25.2	2.0	1.4	2.3	34.0	3.3	0.1	9.0	12.2	59.0	10.6	10.0	1.8	33.1	3.6	1.9	30.9	2.1	1.0	0.5	5.7	19.3	7.5	1.5	1.3	3.1	36.2	30.1	211.6	0.4	0.0	6.9	6.5	0.4	0.4	1.0	1.0	0.7	2.2	0.0	9.8	6.2
ALDH3B2	ALDH8	ENSG00000132746	"Aldehyde dehydrogenase 3 family member B2"	P48448	11	67662160-67681224	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"breast: 73.0;esophagus: 152.2;skin 1: 123.0;vagina: 41.0"	"Cell type enhanced"	"Detected in some"		"Breast glandular cells: 26.2;Endometrial ciliated cells: 12.6;Glandular and luminal cells: 28.1;Squamous epithelial cells: 53.3;Suprabasal keratinocytes: 14.8;Syncytiotrophoblasts: 14.6"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	5	"MCF7: 71.9;SK-BR-3: 70.7"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			HPA045132	Approved					NA	NA				"Cluster 11: Squamous epithelial cells - Epithelial cell function"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 61: Squamous epithelial cells - Keratinization"			"HPA045132: AB_10795993"	"unprognostic (2.25e-1)"	"unprognostic (2.41e-1)"	"unprognostic (1.65e-1)"	"unprognostic (8.65e-2)"		"unprognostic (2.13e-1)"	"unprognostic (6.09e-2)"	"unprognostic (3.12e-2)"	"unprognostic (6.32e-2)"	"unprognostic (1.48e-1)"	"unprognostic (5.56e-2)"	"unprognostic (1.24e-2)"	"unprognostic (1.40e-2)"	"unprognostic (2.59e-2)"	"unprognostic (1.61e-1)"	"unprognostic (1.15e-2)"	"unprognostic (5.92e-2)"	0.3	0.0	0.1	0.1	0.0	0.2	73.0	0.0	0.0	14.4	0.0	0.1	0.1	0.8	6.8	152.2	4.6	0.3	0.1	0.0	0.0	0.7	0.1	0.4	0.0	0.0	0.0	0.0	0.3	5.2	0.1	3.2	0.0	3.3	0.1	0.5	17.3	4.8	0.3	123.0	0.0	0.1	0.0	0.0	0.3	0.1	0.0	2.4	0.0	0.0	21.1	8.3	41.0	0.0	0.2	0.0	0.1	0.1	0.0	0.0	7.9	0.0	0.0	0.1	0.0	1.3	3.5	3.3	0.1	0.0	0.1	3.1	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	1.3	0.0	6.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	71.9	6.8	0.0	0.1	9.0	0.0	0.0	0.0	1.9	0.0	13.0	0.0	0.1	0.0	70.7	0.1	0.4	15.3	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	2.3	0.0	0.0	1.7	1.2	4.9	1.2	0.0	26.2	7.2	0.4	0.0	7.3	5.5	0.0	10.6	0.2	0.0	1.9	1.1	0.0	12.6	2.6	0.2	0.0	0.0	0.1	0.2	10.6	0.2	0.0	28.1	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	2.0	0.0	0.8	0.0	0.0	0.2	1.8	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	1.1	0.0	0.0	2.8	0.0	0.0	0.0	0.5	0.0	0.0	53.3	14.8	14.6	0.2	0.0	0.0	7.6
ALDH4A1	"ALDH4, P5CDh"	ENSG00000159423	"Aldehyde dehydrogenase 4 family member A1"	P30038	1	18871430-18902724	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Proline metabolism"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"kidney: 200.4;liver: 436.6"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 78.0;Hepatocytes: 385.1;Proximal tubular cells: 279.4;Syncytiotrophoblasts: 86.6"	"Cancer enhanced"	"Detected in all"		"liver cancer: 72.0"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in all"		"Hep G2: 83.7;SK-BR-3: 85.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004645, HPA006401, HPA072759"	Enhanced		Supported	Mitochondria		NA	NA		58000	"Cluster 7: Monocytes - Unknown function"	"Cluster 15: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Mitochondria		"CAB004645: AB_425775, HPA006401: AB_1844731, HPA072759: "	"unprognostic (1.17e-1)"	"prognostic favorable (5.06e-4)"	"unprognostic (1.38e-2)"	"unprognostic (4.16e-2)"	"unprognostic (3.15e-1)"	"unprognostic (7.67e-2)"	"unprognostic (1.28e-1)"	"unprognostic (6.18e-2)"	"unprognostic (1.92e-1)"	"unprognostic (1.09e-2)"	"unprognostic (1.02e-1)"	"unprognostic (2.06e-1)"	"unprognostic (4.27e-3)"	"unprognostic (9.41e-3)"	"unprognostic (3.83e-1)"	"unprognostic (2.69e-3)"	"unprognostic (9.34e-2)"	70.8	16.1	73.9	3.9	88.9	11.7	21.6	73.8	95.9	12.6	106.5	6.8	1.6	9.8	4.7	36.3	8.3	5.5	33.0	68.2	73.8	200.4	436.6	6.2	3.4	72.9	82.8	7.3	4.6	23.0	9.7	13.2	70.0	29.5	2.7	6.5	9.1	27.1	74.2	19.2	4.7	7.1	65.6	7.5	12.5	3.2	92.4	11.7	7.1	74.8	4.2	19.3	16.8	66.1	12.7	17.8	9.5	29.2	40.0	5.7	25.2	13.1	7.1	11.8	9.5	13.7	8.9	8.8	16.6	15.6	5.7	34.0	16.7	35.4	4.5	4.8	15.9	5.9	5.0	83.7	12.6	4.4	15.1	15.6	19.2	6.5	6.6	9.0	13.5	14.0	21.0	5.7	8.1	32.3	4.3	20.2	4.7	26.0	10.1	27.9	8.4	10.0	12.1	32.0	19.6	7.6	21.9	85.0	16.1	14.7	38.7	6.3	11.3	10.2	14.0	12.2	4.5	7.1	17.9	2.5	3.4	33.7	13.5	0.0	2.7	1.5	0.6	3.6	0.5	0.8	0.3	0.8	4.4	0.7	0.2	0.5	0.3	0.1	2.0	1.5	0.6	1.5	73.9	88.9	73.8	95.9	68.2	73.8	72.9	82.8	70.0	65.6	92.4	66.1	2.6	0.0	2.8	27.1	4.3	7.5	17.9	12.5	17.6	3.7	9.8	8.5	20.9	34.3	2.9	46.0	10.4	78.0	2.0	2.0	46.9	6.5	0.5	1.1	1.7	3.1	2.4	32.2	1.2	0.9	12.6	3.2	7.7	3.9	4.5	2.1	15.4	385.1	13.8	20.2	1.6	3.6	6.1	17.2	1.4	0.6	1.2	4.7	3.6	1.9	10.9	14.0	1.0	5.5	1.3	2.5	1.8	2.6	4.4	12.0	0.3	279.4	1.7	4.8	6.6	2.6	4.7	2.2	3.9	21.7	5.4	86.6	2.6	4.5	4.0	9.5
ALDH5A1	"SSADH, SSDH"	ENSG00000112294	"Aldehyde dehydrogenase 5 family member A1"	P51649	6	24494867-24537207	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 98.8"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 90.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"Daudi: 136.6;U-698: 173.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA029715, HPA029716"	Enhanced		Supported	Mitochondria		NA	NA		50000	"Cluster 30: Non-specific - Translation"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Mitochondria		"HPA029715: AB_10599994, HPA029716: AB_10601876"	"unprognostic (7.43e-2)"	"unprognostic (1.12e-3)"	"unprognostic (1.80e-1)"	"unprognostic (1.22e-1)"	"unprognostic (2.23e-1)"	"unprognostic (3.27e-1)"	"prognostic favorable (7.61e-6)"	"unprognostic (2.38e-2)"	"unprognostic (2.17e-2)"	"prognostic favorable (6.20e-4)"	"unprognostic (1.43e-2)"	"unprognostic (1.21e-1)"	"prognostic favorable (3.68e-4)"	"unprognostic (1.04e-2)"	"unprognostic (1.16e-1)"	"unprognostic (2.00e-2)"	"unprognostic (1.08e-2)"	9.4	6.1	27.8	5.9	28.9	4.4	5.2	25.0	32.7	5.4	18.8	8.5	11.8	4.8	3.7	7.3	19.0	5.1	14.5	26.5	32.8	27.8	98.8	6.4	13.6	26.7	35.0	7.3	8.2	19.4	5.8	2.4	27.3	8.2	7.1	11.0	5.2	5.2	57.9	9.5	8.0	3.1	29.4	6.8	7.7	4.5	34.0	26.8	17.0	33.8	12.9	6.7	8.4	24.9	11.5	9.3	6.5	10.1	0.1	0.0	11.7	0.8	2.0	2.4	1.6	35.1	2.5	136.6	21.1	1.0	2.2	0.1	10.5	1.3	1.5	14.7	20.2	20.7	5.9	42.4	1.6	32.2	2.7	1.0	4.4	0.2	0.0	7.1	0.1	34.7	10.4	0.0	1.8	23.3	40.4	19.0	2.7	18.4	5.5	46.1	1.4	1.3	7.7	19.6	11.7	10.5	12.1	1.2	13.2	2.8	19.4	17.5	0.2	1.1	6.7	0.3	7.1	19.4	32.2	173.7	0.2	9.8	1.4	0.3	0.0	0.1	1.0	0.0	1.9	2.2	1.4	1.5	0.1	2.0	3.8	3.4	0.2	0.8	0.1	2.4	0.9	0.7	27.8	28.9	25.0	32.7	26.5	32.8	26.7	35.0	27.3	29.4	34.0	24.9	2.9	16.0	25.3	14.0	9.7	1.7	5.6	8.2	2.2	12.9	7.5	3.4	34.8	11.5	9.4	7.3	16.7	6.1	7.4	6.1	1.9	1.6	0.8	15.2	5.0	3.7	8.4	16.0	18.1	1.0	5.2	3.5	5.6	5.4	7.0	13.5	6.8	90.7	3.9	16.8	32.4	11.7	2.0	3.8	1.8	0.3	3.4	1.7	1.8	8.4	0.2	11.8	3.1	11.6	2.4	1.3	7.7	4.5	12.2	4.1	13.4	26.8	12.8	6.9	0.0	6.9	2.3	1.7	6.6	8.7	3.0	1.9	5.4	8.0	17.0	13.1
ALDH6A1	MMSDH	ENSG00000119711	"Aldehyde dehydrogenase 6 family member A1"	Q02252	14	74056847-74084492	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"		Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in all"	5	"kidney: 379.1;liver: 367.1"	"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 201.5;Hepatocytes: 523.6;Proximal tubular cells: 962.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"eosinophil: 43.2"	"Lineage enriched"	"Detected in all"	4	"granulocytes: 43.2"	"Cell line enhanced"	"Detected in all"		"T-47d: 57.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA029072, HPA029073, HPA029074, HPA029075"	Enhanced		Enhanced	Mitochondria		No	No		37000	"Cluster 2: Granulocytes - Unknown function"	"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 6: T47d - Mammary gland"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Mitochondria		"HPA029072: AB_10599176, HPA029073: AB_10601877, HPA029074: AB_10601000, HPA029075: AB_10602005"	"unprognostic (1.45e-1)"	"unprognostic (5.38e-2)"	"unprognostic (6.89e-2)"	"unprognostic (6.95e-3)"	"unprognostic (1.46e-1)"	"unprognostic (7.93e-2)"	"unprognostic (1.11e-3)"	"prognostic favorable (4.22e-4)"	"unprognostic (1.58e-1)"	"unprognostic (9.10e-2)"	"unprognostic (3.11e-2)"	"unprognostic (2.13e-1)"	"prognostic favorable (2.00e-15)"	"unprognostic (4.59e-1)"	"unprognostic (1.92e-1)"	"unprognostic (6.05e-3)"	"unprognostic (1.12e-1)"	38.7	14.7	58.6	4.8	66.0	3.3	14.4	58.8	59.3	17.3	61.4	15.2	26.6	11.4	9.8	9.8	12.8	9.4	40.3	51.0	54.0	379.1	367.1	9.4	5.1	63.3	54.0	28.3	23.4	37.0	6.6	7.6	55.6	25.4	15.8	15.2	19.8	16.1	27.5	6.2	23.4	9.0	56.4	5.4	24.0	17.1	69.8	5.7	28.3	34.8	5.3	11.4	7.0	62.6	8.9	7.8	11.0	23.5	39.3	19.2	17.5	6.3	11.8	6.8	11.5	17.3	10.2	10.5	13.6	13.5	5.3	4.8	24.9	7.0	14.5	9.5	3.5	5.1	8.0	19.2	45.0	2.7	2.4	28.2	12.0	8.7	20.7	17.0	12.0	23.7	8.1	14.7	4.6	36.2	7.6	4.0	8.7	32.6	5.2	15.1	11.2	14.6	9.2	5.8	4.4	7.0	21.0	21.9	5.7	18.0	57.5	9.6	3.8	7.4	9.0	11.7	2.4	9.3	18.9	10.2	9.9	3.2	7.3	29.1	6.2	43.2	6.9	4.8	10.6	7.2	7.8	8.4	9.2	6.1	9.9	7.0	2.4	9.7	4.2	5.3	6.1	4.9	58.6	66.0	58.8	59.3	51.0	54.0	63.3	54.0	55.6	56.4	69.8	62.6	15.4	38.5	60.4	24.5	11.8	9.2	26.8	10.0	20.5	20.6	28.4	18.9	81.4	67.2	22.9	66.2	4.2	31.0	7.1	18.9	201.5	11.6	23.4	26.2	27.5	27.0	16.9	28.6	5.5	3.1	14.8	25.9	34.7	90.2	7.6	27.1	87.4	523.6	17.7	11.8	10.0	39.3	8.2	26.5	8.9	19.0	28.9	13.4	24.9	1.9	15.8	98.5	9.2	12.5	23.4	4.1	16.3	48.2	8.0	27.6	55.3	962.4	15.4	17.0	13.1	25.6	16.9	11.0	4.2	25.2	7.4	30.6	11.0	10.2	35.7	17.2
ALDH7A1	"ATQ1, EPD, PDE"	ENSG00000164904	"Aldehyde dehydrogenase 7 family member A1"	P49419	5	126531200-126595362	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, Epilepsy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 162.2"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 414.1;Proximal tubular cells: 302.1;Syncytiotrophoblasts: 222.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"plasmacytoid DC: 6.4"	"Lineage enriched"	"Detected in many"	5	"dendritic cells: 6.4"	"Cell line enhanced"	"Detected in many"		"HBEC3-KT: 256.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA023296, HPA053675"	Enhanced		Supported	Mitochondria,Cytosol		Yes	No		430000	"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 15: Liver - Metabolism"	"Cluster 23: AN3-CA - Transcription regulation"	"Cluster 47: Cytotrophoblasts - Unknown function"	Mitochondria	Cytosol	"HPA023296: AB_1844738, HPA053675: "	"unprognostic (1.37e-1)"	"unprognostic (9.67e-2)"	"unprognostic (2.07e-2)"	"unprognostic (2.20e-2)"	"unprognostic (4.15e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.58e-3)"	"unprognostic (9.49e-3)"	"unprognostic (7.61e-2)"	"unprognostic (7.08e-2)"	"unprognostic (2.10e-1)"	"unprognostic (1.33e-1)"	"prognostic favorable (3.08e-4)"	"unprognostic (1.51e-1)"	"unprognostic (3.70e-1)"	"unprognostic (3.10e-3)"	"unprognostic (4.93e-2)"	23.7	38.3	46.6	9.1	47.6	1.8	47.1	43.7	45.8	32.7	40.7	29.5	23.7	25.1	8.8	35.9	28.8	19.1	27.9	44.7	43.2	115.1	162.2	15.7	8.6	43.1	43.5	65.3	27.0	34.0	8.8	44.9	42.6	42.0	27.4	19.7	40.6	27.9	12.2	29.4	21.0	23.6	44.8	7.0	23.6	12.3	44.0	18.3	47.6	26.5	17.1	18.1	20.9	45.2	64.9	41.9	116.6	193.4	95.5	56.4	147.8	76.1	93.4	86.5	110.5	118.6	60.7	0.0	75.5	60.0	36.1	47.1	36.5	256.2	78.8	0.1	44.6	12.3	63.1	102.1	46.3	0.2	0.0	69.0	59.2	67.3	47.7	64.2	70.0	0.0	0.0	0.1	77.1	42.1	2.6	0.3	79.4	47.5	35.2	38.9	131.8	0.0	81.2	48.4	39.4	47.2	0.0	41.1	44.7	89.0	75.2	2.7	86.1	24.8	75.6	28.8	53.1	0.1	0.1	0.4	13.4	0.2	40.6	0.7	0.2	0.1	0.1	0.0	0.2	0.8	0.2	0.1	1.8	0.6	1.2	0.6	0.1	0.1	0.0	6.4	0.0	0.4	46.6	47.6	43.7	45.8	44.7	43.2	43.1	43.5	42.6	44.8	44.0	45.2	17.6	16.0	29.3	99.3	5.0	25.9	59.5	110.0	87.0	23.6	40.6	91.1	39.9	27.1	43.5	42.3	22.9	414.1	3.7	15.2	76.3	43.5	31.4	18.7	44.3	19.1	21.7	5.2	16.0	13.8	107.8	34.0	27.0	21.4	7.0	50.4	18.9	74.6	51.1	25.2	21.5	25.9	20.3	9.4	7.6	41.7	25.4	9.1	55.2	12.2	7.5	102.1	0.0	41.7	30.0	12.6	15.6	37.2	2.0	27.5	23.4	302.1	23.4	13.6	19.7	19.4	25.8	1.0	5.1	59.2	16.1	222.3	4.6	39.3	46.4	50.4
ALDH8A1	ALDH12	ENSG00000118514	"Aldehyde dehydrogenase 8 family member A1"	Q9H2A2	6	134917393-134950115	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	16	"kidney: 72.2;liver: 247.2"	"Group enriched"	"Detected in some"	4	"Hepatocytes: 142.5;Proximal tubular cells: 136.9"	"Group enriched"	"Detected in some"	7	"liver cancer: 26.3;renal cancer: 17.6"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"basophil: 2.5"	"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in some"		"HEK 293: 2.9;Hep G2: 2.9;K-562: 3.0;RPTEC TERT1: 3.3;U-266/70: 2.8"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in some"			"HPA026292, HPA055414"	Enhanced		Approved	Nucleoplasm,Centrosome		NA	NA		110000	"Cluster 46: Basophils - DNA binding"	"Cluster 85: Liver - Metabolism"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Centrosome	Nucleoplasm	"HPA026292: AB_1844741, HPA055414: AB_2682810"	"unprognostic (1.12e-1)"	"unprognostic (1.48e-1)"	"unprognostic (1.88e-1)"	"unprognostic (1.75e-1)"	"unprognostic (2.70e-2)"	"unprognostic (6.32e-2)"	"unprognostic (4.30e-3)"	"unprognostic (1.12e-1)"	"unprognostic (3.98e-2)"	"unprognostic (1.64e-1)"	"unprognostic (2.39e-2)"	"unprognostic (3.99e-2)"	"prognostic favorable (9.87e-4)"	"unprognostic (1.25e-2)"	"unprognostic (1.36e-1)"	"unprognostic (2.36e-2)"	"unprognostic (5.86e-5)"	1.3	1.3	6.4	0.7	7.1	2.4	1.2	6.9	9.8	1.5	2.2	3.3	0.8	1.2	2.1	0.8	1.0	0.9	0.7	6.5	3.8	72.2	247.2	0.9	0.6	5.3	4.4	0.5	0.9	0.4	0.8	0.5	6.2	1.7	0.8	2.8	0.8	0.8	3.6	1.7	1.1	0.9	3.1	1.3	1.2	0.5	5.4	0.7	0.6	0.3	0.6	1.9	0.9	8.3	0.1	0.5	0.8	0.5	0.2	0.1	0.6	0.2	0.2	0.0	0.5	0.2	0.3	0.1	0.2	0.0	0.1	0.6	0.6	0.0	0.4	0.6	2.9	2.0	2.1	2.9	0.3	0.8	1.0	0.8	0.9	0.2	0.4	0.6	0.2	0.8	3.0	1.1	0.1	0.0	0.9	1.0	0.2	0.2	0.3	0.0	0.2	0.2	3.3	0.4	0.8	0.2	0.1	0.0	0.5	0.2	0.3	0.2	0.2	0.2	1.6	0.6	0.8	2.8	1.0	0.5	0.3	0.7	0.2	2.5	0.3	0.3	0.4	0.1	0.1	0.4	0.4	0.2	0.0	0.4	0.3	0.3	0.8	0.8	0.1	0.4	0.5	0.3	6.4	7.1	6.9	9.8	6.5	3.8	5.3	4.4	6.2	3.1	5.4	8.3	0.3	3.2	0.6	3.6	0.8	0.0	0.2	0.2	0.0	2.6	0.7	0.9	0.6	1.5	0.7	31.3	0.0	0.2	0.3	0.1	19.6	0.2	0.1	0.4	0.4	0.7	0.0	0.0	14.3	0.0	1.7	0.4	0.0	1.6	0.0	0.5	2.5	142.5	0.1	3.3	12.9	0.1	0.0	2.5	0.3	0.0	0.0	0.8	0.0	1.0	0.7	0.3	0.0	3.0	9.6	0.0	0.1	0.0	0.3	0.1	0.0	136.9	0.0	1.8	0.0	1.2	0.5	0.0	0.0	0.0	0.4	0.0	0.9	0.5	0.2	0.1
ALDH9A1	"ALDH4, ALDH7, ALDH9, E3"	ENSG00000143149	"Aldehyde dehydrogenase 9 family member A1"	P49189	1	165662216-165698863	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Muller glia cells: 311.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"											"HPA006077, HPA010873"	Approved		Approved	Cytosol	"Intracellular and membrane"	NA	NA		2000000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 39: Non-specific - Basic cellular processes"	Cytosol		"HPA006077: , HPA010873: AB_1078126"	"unprognostic (2.24e-1)"	"unprognostic (3.16e-2)"	"unprognostic (4.17e-2)"	"unprognostic (1.25e-1)"	"unprognostic (3.21e-2)"	"unprognostic (1.25e-1)"	"unprognostic (4.14e-2)"	"unprognostic (4.87e-2)"	"unprognostic (2.30e-1)"	"unprognostic (1.83e-1)"	"prognostic favorable (4.56e-4)"	"unprognostic (5.51e-2)"	"unprognostic (9.05e-2)"	"unprognostic (1.67e-1)"	"unprognostic (1.49e-1)"	"unprognostic (1.43e-1)"	"unprognostic (2.15e-1)"	119.2	105.5	49.6	29.8	51.0	24.8	76.8	49.3	60.3	51.5	62.5	45.7	54.8	38.6	93.4	105.6	50.2	32.0	48.2	47.4	57.5	142.4	206.5	38.5	40.3	50.5	52.1	53.6	44.0	81.9	39.9	38.0	51.4	65.3	50.6	46.4	104.1	45.6	93.6	54.7	48.6	42.0	50.7	37.9	39.5	63.4	49.3	39.0	123.0	56.4	60.1	39.4	43.9	55.6	55.7	53.5	48.7	44.1	152.1	132.8	40.7	71.9	101.5	70.8	61.0	33.4	40.7	0.1	67.1	64.8	34.9	42.8	40.0	70.3	83.0	25.9	50.6	35.3	34.7	36.5	78.2	56.0	36.1	86.0	34.8	75.2	62.5	97.8	62.2	45.9	56.9	48.4	111.7	33.4	37.6	57.6	71.3	145.1	64.7	31.7	62.0	74.3	92.5	52.0	57.7	39.8	51.4	57.1	67.4	65.6	108.8	84.0	61.9	42.5	41.5	52.4	37.1	44.7	62.5	54.8	47.9	52.6	41.7	61.8	35.2	50.9	45.5	37.7	48.8	49.9	43.8	49.6	34.5	46.8	43.8	50.4	51.3	43.0	45.3	21.6	69.8	45.6	49.6	51.0	49.3	60.3	47.4	57.5	50.5	52.1	51.4	50.7	49.3	55.6	56.2	16.0	47.6	12.7	43.3	32.6	43.3	43.8	68.3	25.0	83.0	54.6	46.5	55.8	36.8	51.5	22.9	48.5	39.3	43.9	97.8	42.9	45.4	27.7	39.1	49.4	55.8	28.2	5.6	37.0	76.4	60.6	36.2	20.4	38.0	60.9	59.3	158.8	61.9	13.5	8.3	56.9	32.6	59.1	24.9	39.8	95.4	43.8	56.9	6.5	34.6	311.5	39.1	12.1	12.2	32.2	33.1	115.5	34.8	39.6	80.3	204.4	59.4	28.9	26.3	32.5	40.1	85.6	49.9	123.8	51.9	38.2	43.7	148.4	63.6	28.3
ALKBH1	"ABH, alkB, ALKBH, hABH"	ENSG00000100601	"AlkB homolog 1, histone H2A dioxygenase"	Q13686	14	77672404-77708023	"Enzymes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, RNA repair, Translation regulation"	"Dioxygenase, Lyase, Multifunctional enzyme, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA044087, HPA060061"	Approved		Supported	"Nucleoplasm,Endoplasmic reticulum"	"Intracellular and membrane"	NA	NA			"Cluster 34: Basophils - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 66: Spermatocytes - Spermatogenesis"	Nucleoplasm	"Endoplasmic reticulum"	"HPA044087: AB_2678803, HPA060061: "	"unprognostic (1.92e-2)"	"unprognostic (8.38e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.37e-3)"	"unprognostic (3.41e-2)"	"unprognostic (5.03e-2)"	"unprognostic (3.74e-3)"	"unprognostic (7.45e-3)"	"unprognostic (2.68e-2)"	"unprognostic (3.95e-2)"	"unprognostic (5.05e-3)"	"unprognostic (2.16e-2)"	"prognostic favorable (1.80e-4)"	"unprognostic (1.65e-3)"	"unprognostic (1.46e-1)"	"unprognostic (2.63e-1)"	"unprognostic (2.44e-2)"	2.7	2.7	2.8	1.8	3.2	1.2	3.5	3.9	3.5	3.4	2.7	2.8	2.5	2.3	2.1	2.6	2.9	2.2	4.1	3.0	3.5	3.0	3.6	2.2	3.5	2.8	3.2	2.9	2.6	3.3	1.5	3.9	2.9	3.1	3.4	2.9	2.1	3.1	5.7	2.6	2.1	2.9	3.0	2.3	2.5	3.0	3.2	4.4	3.1	7.4	4.1	3.1	2.2	3.3	5.2	7.5	6.0	4.1	6.3	6.8	7.4	5.3	6.8	11.3	12.7	7.7	3.1	7.9	2.9	4.8	5.3	4.5	13.2	5.7	13.2	5.4	5.1	4.2	4.0	6.4	8.9	4.5	2.6	5.8	9.2	6.6	10.5	5.0	9.4	6.1	6.6	4.4	6.1	8.1	6.0	5.7	6.6	7.7	9.6	6.0	6.0	5.3	6.4	4.5	7.6	5.7	4.3	4.5	5.7	4.9	10.9	4.5	4.3	4.7	4.7	5.2	4.3	5.4	9.4	7.6	3.2	6.3	4.7	10.7	3.0	1.4	2.9	3.5	2.4	3.4	2.7	2.8	3.0	2.7	2.8	2.2	0.8	3.6	2.4	1.6	3.3	2.2	2.8	3.2	3.9	3.5	3.0	3.5	2.8	3.2	2.9	3.0	3.2	3.3	6.5	0.0	3.9	13.1	7.3	8.4	5.7	6.2	6.8	4.1	5.4	4.4	7.5	1.5	4.5	1.8	2.1	9.9	3.5	4.2	9.8	6.2	4.8	4.4	4.5	5.7	2.4	4.2	15.9	7.0	8.8	5.5	2.6	3.8	9.5	6.1	2.2	3.9	7.6	0.0	15.8	4.9	6.1	5.2	5.0	4.2	6.5	7.7	5.4	5.6	6.6	7.8	4.1	16.1	19.4	6.8	1.5	5.3	4.9	4.5	7.0	6.5	5.5	5.3	6.6	4.2	5.6	21.1	15.9	4.4	5.4	12.2	5.6	5.1	4.8	3.7
ALKBH2	"ABH2, MGC90512"	ENSG00000189046	"AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase"	Q6NS38	12	109088188-109093631	"Enzymes, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB011198, HPA045392, HPA051976"	Approved		Enhanced	Nucleoplasm		NA	NA			"Cluster 30: Non-specific - Translation"	"Cluster 15: Liver - Metabolism"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 39: Non-specific - Basic cellular processes"	Nucleoplasm		"CAB011198: AB_261971, HPA045392: AB_2679309, HPA051976: AB_2681680"	"prognostic favorable (6.67e-5)"	"unprognostic (3.66e-3)"	"unprognostic (1.08e-1)"	"unprognostic (4.64e-2)"	"unprognostic (4.55e-2)"	"unprognostic (4.71e-2)"	"unprognostic (1.69e-1)"	"unprognostic (9.60e-2)"	"unprognostic (3.63e-1)"	"unprognostic (1.85e-1)"	"unprognostic (6.39e-2)"	"unprognostic (6.43e-3)"	"prognostic unfavorable (1.41e-5)"	"unprognostic (1.01e-2)"	"unprognostic (7.88e-2)"	"unprognostic (6.24e-2)"	"prognostic favorable (8.67e-4)"	22.1	14.7	17.0	13.1	18.8	8.5	22.3	17.9	18.5	19.9	15.0	16.7	7.9	21.6	9.3	18.0	20.4	8.2	14.6	17.1	18.1	15.2	31.8	12.3	16.8	18.5	18.3	21.8	19.1	6.1	9.8	7.2	18.6	15.4	9.1	4.5	15.6	11.3	25.3	27.7	15.0	13.8	17.7	15.1	16.8	11.3	18.1	11.3	15.1	12.1	14.0	19.1	18.6	20.8	35.1	58.6	33.0	74.1	22.7	30.3	52.2	22.9	15.2	23.7	26.7	62.3	24.6	53.5	22.1	13.3	11.1	25.1	55.9	23.0	13.8	48.0	50.0	26.8	35.3	57.9	30.1	37.2	23.9	31.4	48.9	22.2	56.5	28.7	9.1	50.5	40.3	31.0	16.3	61.6	34.8	74.5	45.6	36.6	59.1	30.4	32.0	57.7	31.5	48.1	33.8	58.0	24.2	77.4	50.9	12.3	47.5	22.1	9.6	26.0	28.5	25.0	34.1	43.1	54.6	119.2	22.4	31.8	42.7	2.9	8.1	1.4	12.4	11.2	21.8	27.4	18.4	17.5	8.5	27.6	27.1	16.2	1.5	16.7	7.6	21.6	15.8	10.4	17.0	18.8	17.9	18.5	17.1	18.1	18.5	18.3	18.6	17.7	18.1	20.8	23.7	9.6	6.3	4.2	15.9	50.9	52.2	19.4	42.1	3.6	25.2	44.3	6.2	12.8	16.3	9.2	2.1	17.5	12.5	3.1	15.6	26.5	12.2	7.2	27.9	17.3	8.4	10.9	3.5	24.0	25.0	20.6	14.3	8.6	6.3	9.5	6.1	21.4	9.8	5.0	3.6	11.6	18.3	8.2	11.7	5.4	26.8	6.8	26.6	3.7	4.9	11.2	7.2	6.0	7.6	24.1	5.1	17.3	13.1	46.7	7.4	20.2	10.0	7.4	0.0	44.5	26.0	7.9	32.0	35.9	60.0	5.1	12.6	24.5	14.8	25.3
ALKBH3	DEPC-1	ENSG00000166199	"AlkB homolog 3, alpha-ketoglutarate dependent dioxygenase"	Q96Q83	11	43880811-43920274	"Enzymes, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 90.9;Late spermatids: 103.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"							"HPA009674, HPA046489"	Approved		Supported	Nucleoplasm,Mitochondria		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 34: Spermatids - Unknown function"	Nucleoplasm	Mitochondria	"HPA009674: AB_1850460, HPA046489: AB_2679671"	"unprognostic (3.53e-1)"	"unprognostic (2.41e-1)"	"unprognostic (7.43e-3)"	"unprognostic (4.70e-2)"	"unprognostic (6.94e-3)"	"unprognostic (1.89e-1)"	"unprognostic (7.71e-2)"	"unprognostic (5.42e-2)"	"unprognostic (8.56e-2)"	"unprognostic (4.62e-1)"	"unprognostic (5.87e-2)"	"unprognostic (7.02e-2)"	"unprognostic (2.09e-2)"	"unprognostic (1.22e-1)"	"unprognostic (2.31e-1)"	"unprognostic (2.76e-1)"	"unprognostic (1.35e-2)"	20.6	15.7	14.6	9.1	16.0	7.9	20.6	18.3	20.9	21.3	15.7	18.3	10.9	20.5	24.7	18.5	19.5	9.2	15.3	15.3	15.4	16.7	18.5	13.2	13.8	15.5	15.2	22.9	23.6	16.9	18.2	7.3	15.3	21.9	12.8	17.0	19.3	13.5	35.2	23.4	15.9	13.6	15.3	19.6	20.0	20.4	15.2	15.9	15.3	25.8	14.6	19.2	19.9	17.6	15.8	26.0	10.7	0.0	20.3	26.1	0.0	19.5	42.0	36.9	34.7	10.7	12.0	2.6	12.2	28.7	20.5	21.3	14.6	32.3	33.1	0.0	49.6	23.7	17.1	27.4	51.9	44.5	30.5	27.8	55.7	17.0	81.4	15.2	26.5	44.7	33.9	25.9	18.3	18.4	38.6	21.9	20.6	16.2	38.5	11.6	23.8	30.3	21.3	23.2	20.3	16.1	15.7	22.6	37.1	9.7	32.9	26.3	20.6	21.6	12.5	35.7	28.0	23.1	25.1	26.3	31.3	18.3	17.6	34.4	16.4	9.4	19.8	18.4	19.3	18.6	20.9	18.2	23.5	21.8	24.8	22.9	2.9	24.6	29.4	20.9	21.3	17.4	14.6	16.0	18.3	20.9	15.3	15.4	15.5	15.2	15.3	15.3	15.2	17.6	12.0	16.0	10.9	15.0	12.6	10.3	8.8	16.5	10.8	11.5	10.9	12.8	6.8	14.3	13.3	16.5	4.2	3.4	13.7	9.8	31.3	24.6	90.9	6.3	7.3	14.6	9.5	9.9	15.8	32.6	4.6	14.0	10.2	4.8	7.6	12.5	13.2	12.9	19.0	10.1	15.8	11.3	6.1	11.2	7.0	103.3	16.1	13.1	17.8	3.7	14.1	20.4	22.6	13.0	16.1	27.7	8.6	10.5	12.4	9.3	15.5	17.1	14.0	13.0	6.6	9.9	15.3	29.3	12.6	20.6	7.1	2.2	12.7	15.7	12.5	8.3
ALKBH4	FLJ20013	ENSG00000160993	"AlkB homolog 4, lysine demethylase"	Q9NXW9	7	102456238-102464863	"Enzymes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Actin-binding, Chromatin regulator, Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA051422	Approved					NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 32: Brain & Lymphoid tissue - Unknown function"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 39: Non-specific - Basic cellular processes"			"HPA051422: AB_2681480"	"unprognostic (1.18e-2)"	"unprognostic (7.35e-2)"	"unprognostic (3.50e-2)"	"unprognostic (1.75e-2)"	"unprognostic (4.14e-3)"	"unprognostic (3.83e-2)"	"unprognostic (2.71e-3)"	"unprognostic (6.04e-3)"	"unprognostic (1.34e-1)"	"unprognostic (7.25e-3)"	"unprognostic (3.20e-3)"	"unprognostic (1.10e-1)"	"prognostic favorable (3.09e-4)"	"unprognostic (1.44e-2)"	"unprognostic (2.04e-1)"	"unprognostic (2.23e-1)"	"unprognostic (5.44e-2)"	3.4	5.2	8.3	2.9	9.0	5.0	3.6	10.0	9.4	4.3	7.6	3.9	3.9	4.6	3.5	4.2	3.8	2.3	4.2	8.7	8.8	5.0	4.9	2.7	4.3	8.5	8.5	4.0	5.0	6.9	5.1	2.9	8.8	4.1	2.6	2.3	5.0	3.2	4.3	4.9	5.0	2.9	8.6	7.1	4.3	2.7	8.9	4.4	5.8	4.3	3.3	3.7	3.8	9.2	5.4	7.2	5.9	13.9	4.0	4.5	6.5	4.0	6.9	8.4	7.9	8.2	7.1	6.3	6.6	5.7	7.4	4.3	7.6	5.6	6.2	6.3	15.9	6.3	3.3	6.0	6.2	5.6	5.9	6.8	7.6	6.5	2.9	7.2	5.5	10.1	11.2	7.5	5.2	19.6	15.7	17.5	9.0	10.2	10.9	9.3	6.2	11.2	7.0	5.8	7.3	10.9	5.0	15.1	5.6	7.4	6.3	6.6	1.8	8.9	10.2	13.8	8.8	10.2	8.4	11.7	5.2	7.6	9.4	3.7	5.4	3.0	6.1	4.8	6.4	5.2	4.7	8.0	5.4	4.6	4.7	6.1	1.6	9.2	9.8	6.9	4.9	3.4	8.3	9.0	10.0	9.4	8.7	8.8	8.5	8.5	8.8	8.6	8.9	9.2	10.2	6.4	5.8	2.3	7.0	8.3	4.3	12.9	5.2	16.6	8.1	11.7	2.2	11.5	5.9	9.2	4.2	25.6	9.2	7.3	25.4	16.3	1.3	6.8	12.2	10.5	6.1	19.6	5.2	14.9	15.4	10.8	7.7	10.0	3.8	11.7	10.4	9.1	15.3	28.6	6.2	8.1	10.2	12.0	5.8	1.9	14.0	7.2	3.6	2.8	14.6	13.4	25.7	2.0	4.5	11.8	10.6	21.4	8.3	6.3	12.0	18.8	4.6	10.2	0.0	7.6	9.5	11.9	16.9	9.5	7.4	11.1	8.7	17.7	10.1	1.8
ALKBH5	"FLJ20308, OFOXD1"	ENSG00000091542	"AlkB homolog 5, RNA demethylase"	Q6P6C2	17	18183078-18209954	"Enzymes, Predicted intracellular proteins"	"Differentiation, Spermatogenesis"	"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 236.6"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA007196	Approved		Approved	"Nucleoplasm,Golgi apparatus,Cytosol"		NA	NA			"Cluster 26: Non-specific - Mitochondria"	"Cluster 59: Non-specific - Translation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 39: Non-specific - Basic cellular processes"	"Nucleoplasm, Cytosol"	"Golgi apparatus"	"HPA007196: AB_1850461"	"unprognostic (1.07e-1)"	"unprognostic (1.51e-1)"	"unprognostic (2.23e-2)"	"unprognostic (1.48e-2)"	"unprognostic (1.80e-2)"	"unprognostic (1.24e-1)"	"unprognostic (2.23e-1)"	"unprognostic (2.64e-1)"	"unprognostic (1.34e-1)"	"unprognostic (1.94e-2)"	"prognostic favorable (3.75e-4)"	"unprognostic (6.54e-2)"	"unprognostic (3.99e-2)"	"unprognostic (2.88e-2)"	"unprognostic (3.22e-2)"	"unprognostic (4.68e-3)"	"prognostic unfavorable (5.69e-4)"	33.4	40.1	23.7	21.4	21.8	32.6	29.2	18.1	23.5	34.2	17.8	51.1	22.3	45.3	5.2	25.9	43.1	21.6	68.6	20.4	23.4	29.9	33.6	28.8	25.1	23.2	23.7	33.5	36.0	26.6	39.8	17.4	29.5	31.7	10.6	26.5	36.4	25.1	236.6	28.1	31.0	22.0	19.3	26.8	33.6	51.3	26.7	22.2	29.8	98.7	15.8	43.0	29.6	27.4	90.3	86.4	27.8	47.0	37.0	25.0	30.1	41.1	41.8	56.8	51.5	96.1	19.9	53.9	65.4	35.9	29.4	56.2	40.9	33.6	26.8	71.3	74.0	35.4	47.7	41.8	32.5	27.4	53.0	24.3	23.1	41.8	24.7	33.9	31.8	35.3	45.0	20.4	29.8	60.6	60.1	28.6	24.9	28.3	44.4	57.6	56.0	89.0	14.4	31.0	32.5	47.6	44.8	27.2	41.7	90.9	31.4	20.9	38.3	55.8	44.1	87.8	78.0	32.0	25.1	32.2	100.6	38.8	39.0	3.6	7.4	20.4	13.0	7.8	11.9	6.8	13.3	16.1	9.0	10.0	9.5	9.5	4.3	7.2	11.6	5.7	7.4	6.7	23.7	21.8	18.1	23.5	20.4	23.4	23.2	23.7	29.5	19.3	26.7	27.4	37.2	35.3	33.3	17.9	41.1	64.6	29.0	26.8	19.4	80.3	48.7	40.3	93.5	28.6	24.4	27.6	39.6	33.0	59.0	44.9	84.1	27.4	58.9	53.9	36.5	36.6	60.9	24.0	17.0	31.4	44.8	42.4	18.3	36.7	40.7	25.2	35.7	65.2	33.5	119.5	18.1	45.0	22.4	45.3	56.9	42.5	41.0	36.4	49.8	7.5	36.3	76.3	57.7	9.0	24.0	32.8	38.7	51.9	21.1	35.3	47.6	115.2	46.4	58.9	19.7	39.4	47.3	118.7	117.3	20.3	56.0	31.5	48.3	32.7	39.1	28.6
ALOX12	12S-LOX	ENSG00000108839	"Arachidonate 12-lipoxygenase, 12S type"	P18054	17	6996049-7010754	"Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Dioxygenase, Hydrolase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"cervix: 34.6;esophagus: 49.4;vagina: 105.7"	"Cell type enriched"	"Detected in some"	6	"Macrophages: 17.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in some"		"neutrophil: 4.5"	"Low lineage specificity"	"Detected in many"			"Group enriched"	"Detected in many"	5	"A-431: 25.5;HEL: 40.4"	"Region enriched"	"Detected in single"	5	"olfactory bulb: 4.4"					"HPA010691, CAB019287, HPA064819"	Enhanced		Supported	"Nuclear speckles,Vesicles,Cytosol"		NA	NA		49000	"Cluster 9: Neutrophils - Innate immune response"	"Cluster 11: Squamous epithelial cells - Epithelial cell function"	"Cluster 36: HEL - Hemostasis"	"Cluster 51: Myeloid cells - Hemostasis"	Cytosol	"Nuclear speckles, Vesicles"	"CAB019287: , HPA010691: AB_1844756, HPA064819: "	"unprognostic (3.61e-3)"	"unprognostic (6.93e-2)"	"unprognostic (7.17e-5)"	"unprognostic (9.43e-2)"	"unprognostic (6.06e-2)"	"unprognostic (2.25e-3)"	"unprognostic (2.45e-1)"	"unprognostic (3.16e-1)"	"unprognostic (3.02e-2)"	"unprognostic (1.59e-2)"	"unprognostic (3.96e-5)"	"unprognostic (4.01e-3)"	"unprognostic (2.25e-2)"	"unprognostic (1.56e-1)"	"unprognostic (2.87e-1)"	"unprognostic (5.90e-2)"	"unprognostic (3.47e-2)"	1.0	1.5	0.9	3.2	1.5	4.7	0.3	0.1	1.4	34.6	0.6	0.4	1.8	2.2	0.0	49.4	1.2	3.1	1.4	0.4	0.4	0.5	0.2	1.1	3.9	1.3	0.7	1.3	1.9	0.0	0.1	1.1	1.0	0.8	0.1	3.1	20.2	0.0	1.6	21.7	2.0	0.2	0.1	3.3	1.1	1.3	1.2	0.0	1.9	0.1	3.8	1.5	105.7	3.4	25.5	4.2	1.9	1.4	0.0	0.0	1.7	1.6	0.0	0.0	0.0	3.7	0.9	1.3	0.9	0.0	1.4	3.2	0.0	0.1	0.0	2.8	3.2	40.4	6.8	2.8	0.1	0.4	6.5	0.0	0.1	0.0	0.0	2.4	0.0	2.8	2.7	1.4	0.0	0.3	0.5	0.9	1.3	0.2	0.8	1.4	0.8	0.7	0.0	3.2	0.1	0.9	0.7	0.8	0.4	2.4	1.5	1.1	4.6	2.2	1.2	2.1	1.1	0.8	0.3	0.7	1.2	3.0	1.0	2.1	0.9	1.8	0.7	0.4	0.5	1.1	0.5	0.7	0.7	0.6	0.2	0.3	4.5	0.7	0.4	1.3	0.3	13.6	0.9	1.5	0.1	1.4	0.4	0.4	1.3	0.7	1.0	0.1	1.2	3.4	0.0	0.0	0.0	2.0	0.0	0.1	0.2	0.2	0.0	0.0	0.0	0.0	2.2	0.0	0.1	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.2	0.1	0.1	0.1	0.0	0.0	1.1	0.0	0.1	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.0	1.0	0.0	0.0	0.0	0.0	0.1	0.0	17.3	0.0	1.0	0.8	0.0	0.0	2.5	2.4	0.2	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.2	2.5	1.1	0.0	0.1	0.1	0.0	2.0
ALOX15	15-LOX-1	ENSG00000161905	"Arachidonate 15-lipoxygenase"	P16050	17	4630919-4642294	"Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 37.2;fallopian tube: 12.7"	"Group enriched"	"Detected in some"	5	"Club cells: 60.3;Langerhans cells: 72.2;Respiratory ciliated cells: 191.8"	"Cancer enhanced"	"Detected in many"		"cervical cancer: 6.6"	"Low region specificity"	"Detected in some"			"Immune cell enriched"	"Detected in some"	193	"eosinophil: 602.9"	"Lineage enriched"	"Detected in many"	193	"granulocytes: 602.9"	"Group enriched"	"Detected in some"	7	"HMC-1: 15.9;MCF7: 14.7;T-47d: 4.2"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB004962, CAB004963, HPA013859"	Approved					NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"			"CAB004962: , CAB004963: , HPA013859: AB_1844758"	"unprognostic (5.31e-4)"	"unprognostic (1.43e-2)"	"unprognostic (2.81e-2)"	"unprognostic (8.36e-3)"	"unprognostic (2.22e-1)"	"unprognostic (8.60e-2)"	"unprognostic (2.36e-1)"	"unprognostic (2.66e-2)"	"unprognostic (1.70e-2)"	"unprognostic (1.84e-2)"	"unprognostic (2.51e-2)"	"unprognostic (3.77e-1)"	"unprognostic (1.31e-3)"	"unprognostic (1.88e-2)"	"unprognostic (1.30e-1)"	"unprognostic (2.78e-1)"	"unprognostic (1.59e-1)"	37.2	0.0	0.6	1.6	2.0	0.5	3.2	0.0	1.3	0.5	0.0	1.6	1.9	0.0	0.4	0.8	12.7	0.6	2.9	0.5	0.5	0.0	0.1	6.6	1.9	0.3	0.2	0.1	0.0	0.0	3.0	0.1	0.3	0.2	1.0	0.0	0.2	0.3	0.0	2.2	3.3	0.6	0.1	1.4	1.0	1.8	0.4	0.8	0.0	0.0	0.6	1.1	0.1	0.4	1.7	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.2	0.0	0.6	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.1	0.2	0.0	0.0	0.2	0.0	0.0	15.9	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.2	0.0	14.7	0.0	0.3	1.1	1.3	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.1	4.2	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.5	0.0	0.1	0.0	0.2	0.2	602.9	0.0	0.2	0.2	0.1	0.0	0.1	3.1	0.2	0.0	0.1	0.9	0.0	0.1	2.7	0.1	0.4	0.6	2.0	0.0	1.3	0.5	0.5	0.3	0.2	0.3	0.1	0.4	0.4	0.0	0.0	1.1	0.0	0.2	1.5	0.0	13.0	0.0	0.0	1.1	0.1	0.9	11.5	60.3	0.0	0.0	1.8	1.3	0.0	0.0	0.0	19.2	3.0	0.0	0.4	0.0	0.0	0.9	0.0	0.1	3.6	0.0	0.1	1.3	0.0	0.0	0.0	0.6	0.0	0.2	0.0	4.1	0.0	72.2	2.5	0.0	0.6	0.0	0.0	3.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.1	191.8	0.0	0.0	0.1	3.9	1.2	1.2	0.0	0.9	7.4	0.3	0.0	0.0	0.3
ALOX15B	15-LOX-2	ENSG00000179593	"Arachidonate 15-lipoxygenase type B"	O15296	17	8039034-8049134	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Lipid metabolism"	"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"breast: 111.7;prostate: 73.1"	"Cell type enhanced"	"Detected in some"		"Alveolar cells type 2: 75.8;Basal respiratory cells: 22.0;Kupffer cells: 42.2;monocytes: 87.9;Prostatic glandular cells: 25.6;Squamous epithelial cells: 44.4"	"Cancer enriched"	"Detected in all"	5	"prostate cancer: 91.2"	"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	8	"classical monocyte: 3.9;myeloid DC: 4.3"	"Group enriched"	"Detected in many"	8	"dendritic cells: 4.3;monocytes: 3.9"	"Cell line enhanced"	"Detected in some"		"HHSteC: 7.7;HSkMC: 16.6;hTCEpi: 35.1"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			HPA010562	Enhanced		Supported	"Plasma membrane,Cytosol"		NA	NA			"Cluster 25: Monocytes - Inflammatory response"	"Cluster 11: Squamous epithelial cells - Epithelial cell function"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 3: Monocytes - Immune response regulation"	"Plasma membrane, Cytosol"		"HPA010562: AB_2668305"	"unprognostic (1.76e-2)"	"unprognostic (6.47e-2)"	"unprognostic (2.56e-1)"	"unprognostic (2.28e-3)"	"unprognostic (1.67e-2)"	"unprognostic (1.52e-1)"	"unprognostic (1.34e-1)"	"unprognostic (1.52e-1)"	"unprognostic (2.28e-1)"	"unprognostic (1.85e-1)"	"unprognostic (1.44e-2)"	"unprognostic (4.59e-1)"	"unprognostic (1.59e-2)"	"unprognostic (9.37e-2)"	"unprognostic (1.48e-1)"	"unprognostic (2.32e-2)"	"unprognostic (9.49e-2)"	2.2	1.7	0.7	1.3	0.7	0.4	111.7	0.6	2.5	12.0	0.5	2.3	0.1	1.1	0.9	39.1	1.6	0.7	0.7	0.7	0.8	0.5	0.4	24.5	2.9	1.8	0.9	0.7	1.4	0.2	0.5	1.2	1.6	73.1	0.3	0.3	3.7	0.1	0.3	36.9	3.7	0.1	0.9	3.8	4.4	0.5	0.9	0.7	1.9	0.1	7.6	1.7	33.4	1.9	0.1	0.0	0.0	0.1	0.5	0.7	0.3	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	1.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	7.7	0.0	0.0	16.6	35.1	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.3	0.0	0.0	0.0	0.2	0.5	0.0	0.1	0.0	0.9	0.7	0.7	0.6	2.5	0.7	0.8	1.8	0.9	1.6	0.9	0.9	1.9	1.4	0.0	75.8	0.0	0.3	3.1	0.6	22.0	7.4	0.0	19.8	12.3	0.3	1.5	8.2	0.0	0.0	0.2	0.2	0.2	0.0	0.1	1.3	0.0	0.8	0.4	0.0	0.0	0.2	0.4	0.0	0.2	0.0	0.2	1.3	0.0	0.7	0.3	4.2	0.0	0.0	0.0	2.0	42.2	1.1	0.8	0.0	15.4	5.4	0.0	87.9	0.0	0.0	0.0	0.0	0.3	0.0	0.0	1.4	25.6	0.0	0.0	2.2	0.0	0.0	0.1	1.3	0.6	0.8	44.4	1.1	0.8	0.0	0.0	0.0	2.2
ALOX5	5-LOX	ENSG00000012779	"Arachidonate 5-lipoxygenase"	P09917	10	45374176-45446119	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins"	"Leukotriene biosynthesis"	"Dioxygenase, Hydrolase, Oxidoreductase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lung: 72.8;lymphoid tissue: 93.9"	"Cell type enhanced"	"Detected in many"		"B-cells: 63.7;granulocytes: 201.3;Hofbauer cells: 85.0;Kupffer cells: 78.5;Macrophages: 86.5;monocytes: 59.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in some"		"BEWO: 13.9;Daudi: 40.9;HMC-1: 24.0;U-266/70: 30.8;U-698: 11.0"	"Region enriched"	"Detected in single"	4	"white matter: 2.9"	"Low region specificity"	"Detected in all"			HPA071285	Enhanced		Supported	Nucleoplasm		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 64: Macrophages - Immune response"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 57: B-cells - Immune response"	Nucleoplasm		"HPA071285: AB_2686379"	"unprognostic (2.57e-2)"	"unprognostic (2.81e-1)"	"unprognostic (4.82e-2)"	"unprognostic (1.75e-2)"	"unprognostic (7.98e-3)"	"unprognostic (1.26e-1)"	"unprognostic (5.32e-2)"	"unprognostic (8.69e-2)"	"unprognostic (1.86e-2)"	"unprognostic (6.91e-2)"	"unprognostic (5.04e-2)"	"unprognostic (3.42e-1)"	"prognostic unfavorable (1.80e-5)"	"unprognostic (5.59e-3)"	"unprognostic (4.22e-2)"	"unprognostic (1.53e-1)"	"prognostic favorable (7.18e-4)"	16.8	8.4	1.4	8.4	1.1	31.1	12.7	2.8	2.9	6.1	1.0	11.0	3.0	6.9	0.3	10.7	11.1	3.4	6.7	1.2	1.8	8.3	5.5	72.8	6.7	4.1	2.5	2.6	23.2	0.9	3.2	3.6	2.7	11.8	2.3	0.1	14.1	1.5	2.1	5.6	35.8	4.9	2.5	93.9	9.3	2.1	2.2	2.6	4.7	3.7	8.9	40.0	7.9	4.2	0.0	0.0	0.0	0.0	0.0	0.0	13.9	0.0	0.0	0.0	0.0	0.0	7.4	40.9	0.7	0.0	0.0	0.3	0.3	0.0	0.0	0.3	0.1	8.6	0.0	0.0	0.0	0.0	24.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	5.0	0.0	0.0	0.0	0.3	0.0	1.0	0.0	0.1	0.0	2.7	0.0	5.2	0.7	0.0	0.0	0.2	0.0	0.1	0.1	0.6	0.0	0.0	2.2	0.0	0.0	30.8	2.8	11.0	0.0	0.1	0.0	462.5	225.6	317.6	0.3	198.4	0.6	133.9	5.3	1.7	119.7	98.5	0.7	0.5	457.8	0.2	210.5	2.4	1.2	136.1	1.4	1.1	2.8	2.9	1.2	1.8	4.1	2.5	2.7	2.5	2.2	4.2	0.7	16.0	38.4	1.3	63.7	1.1	7.3	0.2	1.2	1.3	7.3	4.3	2.2	12.8	9.5	9.2	2.1	0.7	1.7	1.7	0.0	20.9	0.5	0.7	0.5	3.0	7.1	1.7	2.8	21.6	2.0	1.7	13.7	4.4	201.3	2.2	3.6	1.1	85.0	0.0	1.1	2.0	14.2	78.5	17.8	1.1	0.3	86.5	0.0	47.8	59.5	0.7	4.1	4.0	1.4	18.4	0.6	0.0	13.8	4.0	9.4	0.2	2.6	0.3	13.1	0.3	1.1	0.3	1.1	9.2	1.4	4.1	5.9	0.7	3.2	45.3
AOC1	"ABP, ABP1, DAO"	ENSG00000002726	"Amine oxidase copper containing 1"	P19801	7	150824627-150861504	"Enzymes, Metabolic proteins, Predicted secreted proteins"		"Heparin-binding, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	16	"intestine: 227.2;kidney: 136.5;placenta: 496.7"	"Cell type enhanced"	"Detected in many"		"Collecting duct cells: 272.2;Distal enterocytes: 517.5;Paneth cells: 532.1;Proximal enterocytes: 957.9"	"Group enriched"	"Detected in many"	5	"colorectal cancer: 61.3;endometrial cancer: 39.1;pancreatic cancer: 26.9;renal cancer: 69.4;stomach cancer: 43.2"	"Not detected"	"Not detected"			"Immune cell enriched"	"Detected in some"	12	"eosinophil: 31.2"	"Lineage enriched"	"Detected in many"	22	"granulocytes: 31.2"	"Cell line enhanced"	"Detected in some"		"CAPAN-2: 20.5;HaCaT: 6.2;NB-4: 6.4;RPMI-8226: 7.7;THP-1: 27.1"					"Low region specificity"	"Detected in many"			"HPA031032, HPA031033"	Approved				"Secreted in other tissues"	NA	NA		2500000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 86: Liver & Placenta - Transport via ER"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 45: Enterocytes - Digestion"			"HPA031032: AB_10670150, HPA031033: AB_10669670"	"unprognostic (1.73e-2)"	"unprognostic (2.53e-1)"	"unprognostic (1.58e-2)"	"unprognostic (2.84e-2)"	"unprognostic (6.31e-3)"	"unprognostic (8.31e-3)"	"unprognostic (9.07e-3)"	"unprognostic (6.42e-2)"	"unprognostic (1.21e-1)"	"unprognostic (1.96e-1)"	"unprognostic (3.11e-1)"	"prognostic favorable (1.71e-4)"	"unprognostic (5.32e-3)"	"unprognostic (3.62e-2)"	"unprognostic (1.49e-2)"	"unprognostic (1.69e-1)"	"unprognostic (1.64e-1)"	0.7	0.1	0.3	13.0	0.2	1.9	0.2	0.3	0.3	7.2	0.4	142.2	184.0	2.1	1.9	3.3	0.1	1.8	0.7	0.3	0.2	136.5	5.8	0.6	1.3	0.5	0.5	0.3	1.4	0.0	0.0	496.7	0.5	6.1	94.1	0.1	0.6	1.0	0.1	1.4	227.2	3.4	0.3	0.5	18.0	2.1	0.6	2.1	0.2	0.0	3.8	0.8	0.4	0.5	0.0	0.1	0.1	0.4	0.0	0.0	1.0	0.2	0.0	0.0	0.0	3.2	20.5	0.0	2.7	0.0	1.7	6.2	0.0	0.1	0.0	0.1	0.0	0.1	0.2	0.0	0.0	0.2	0.3	0.0	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.4	0.0	0.3	0.1	6.4	0.2	1.9	0.0	0.0	0.0	7.7	0.3	0.2	2.2	2.5	0.1	0.9	0.0	0.3	0.8	27.1	0.6	0.2	0.1	0.6	0.0	0.2	0.1	0.1	0.2	1.0	0.1	0.2	0.1	31.2	0.0	0.1	0.0	0.0	0.0	0.0	1.4	0.0	0.0	0.0	2.5	0.0	0.0	0.0	0.0	0.1	0.3	0.2	0.3	0.3	0.3	0.2	0.5	0.5	0.5	0.3	0.6	0.5	0.0	0.0	0.0	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.8	0.0	0.8	272.2	0.0	2.1	0.0	517.5	15.6	0.0	7.1	1.9	0.5	0.4	43.3	0.0	0.1	3.3	63.4	0.5	13.7	4.8	5.7	0.0	0.0	0.0	2.8	0.0	0.1	129.7	2.0	0.0	1.7	18.4	0.0	1.0	0.0	0.0	66.2	0.0	0.0	0.0	0.0	3.7	532.1	0.0	0.0	0.7	957.9	145.2	0.2	0.0	0.0	0.0	0.3	3.7	1.3	0.0	0.1	3.4	0.9	0.0	117.9	0.3
AOC2	"DAO2, RAO"	ENSG00000131480	"Amine oxidase copper containing 2"	O75106	17	42844580-42850707	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Catecholamine metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enriched"	"Detected in some"	5	"Early spermatids: 29.5"	"Cancer enhanced"	"Detected in some"		"testis cancer: 3.8"	"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in single"	5	"neutrophil: 1.1"	"Lineage enriched"	"Detected in single"	7	"granulocytes: 1.1"	"Cell line enhanced"	"Detected in many"		"ASC diff: 11.2"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			HPA057779	Uncertain				"Intracellular and membrane"	NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 78: Testis - Spermatogenesis"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 29: Early spermatids - Spermatogenesis"			"HPA057779: "	"unprognostic (3.79e-2)"	"unprognostic (2.33e-1)"	"unprognostic (5.10e-4)"	"unprognostic (1.90e-2)"	"unprognostic (1.48e-2)"	"unprognostic (2.42e-1)"	"unprognostic (4.63e-2)"	"unprognostic (2.63e-2)"	"unprognostic (1.39e-1)"	"unprognostic (3.64e-2)"	"unprognostic (2.16e-2)"	"unprognostic (8.27e-3)"	"unprognostic (4.55e-5)"	"unprognostic (3.55e-2)"	"unprognostic (2.73e-1)"	"unprognostic (1.63e-2)"	"prognostic favorable (2.47e-4)"	5.8	1.1	1.9	0.6	2.1	0.9	2.6	1.9	3.2	1.3	0.6	1.3	0.3	1.0	0.5	0.7	1.6	0.7	0.7	2.4	1.9	1.2	3.4	2.3	0.5	2.0	1.6	1.1	0.7	0.2	2.0	0.4	2.0	1.5	0.2	1.5	0.6	0.5	1.6	1.3	0.8	0.6	1.1	1.6	0.8	4.8	2.0	0.3	0.9	0.6	0.6	1.8	1.2	1.9	0.2	2.3	0.5	2.5	11.2	1.1	6.0	0.8	0.7	1.6	2.2	1.8	0.2	0.9	1.1	0.2	0.7	1.0	2.2	0.6	3.2	2.0	6.0	0.3	1.3	1.9	0.7	0.3	2.2	1.7	2.0	1.5	2.3	0.4	0.4	3.1	0.6	2.1	0.4	0.3	0.5	0.9	0.8	0.2	0.7	1.1	2.3	1.9	0.3	3.6	0.8	0.5	0.1	0.8	3.4	4.6	0.4	0.2	0.4	1.5	3.2	2.0	1.0	4.6	4.9	0.9	0.4	2.2	0.8	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.0	0.0	1.9	2.1	1.9	3.2	2.4	1.9	2.0	1.6	2.0	1.1	2.0	1.9	1.1	0.0	0.5	1.6	0.3	1.0	0.5	0.1	0.0	0.5	0.9	0.9	0.4	0.0	0.7	0.0	2.1	0.1	0.4	0.0	0.0	0.3	29.5	1.4	0.7	1.4	0.0	0.0	1.8	0.4	0.1	0.2	0.0	2.8	0.0	0.5	0.4	0.7	0.1	0.0	1.2	0.2	0.0	0.3	0.6	5.0	0.3	0.3	0.0	0.0	0.0	0.2	0.0	0.0	0.5	0.2	0.1	0.0	0.0	1.2	0.1	0.2	0.4	0.8	0.0	0.5	1.0	2.3	2.1	0.4	1.6	0.0	0.2	0.4	0.2	0.6
AOC3	"HPAO, VAP-1, VAP1"	ENSG00000131471	"Amine oxidase copper containing 3"	Q16853	17	42851184-42858130	"Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"	"Cell adhesion"	Oxidoreductase	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adipose tissue: 422.8"	"Group enriched"	"Detected in many"	4	"Adipocytes: 58.2;Peritubular cells: 74.9;Sertoli cells: 118.3;Smooth muscle cells: 93.0;Theca cells: 74.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	17	"ASC diff: 307.5"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in some"			"HPA000980, CAB025797"	Enhanced		Approved	"Golgi apparatus,Cytosol"	"Secreted - unknown location"	NA	NA		240000000		"Cluster 46: Fibroblasts - ECM organization"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 48: Smooth muscle cells - ECM organization"	Cytosol	"Golgi apparatus"	"CAB025797: , HPA000980: AB_1078170"	"unprognostic (2.20e-1)"	"unprognostic (4.49e-2)"	"prognostic unfavorable (3.68e-4)"	"unprognostic (2.97e-2)"	"unprognostic (1.17e-1)"	"unprognostic (2.64e-1)"	"unprognostic (2.22e-1)"	"unprognostic (2.15e-2)"	"unprognostic (1.48e-1)"	"unprognostic (4.00e-2)"	"unprognostic (2.95e-1)"	"unprognostic (9.02e-2)"	"prognostic unfavorable (1.79e-5)"	"unprognostic (5.61e-2)"	"unprognostic (1.67e-1)"	"unprognostic (8.39e-2)"	"prognostic unfavorable (6.98e-4)"	422.8	48.4	2.6	31.9	3.2	1.4	169.2	2.5	4.2	52.8	2.7	210.8	17.3	95.1	33.5	88.0	84.8	50.7	50.2	2.9	2.5	24.1	19.1	218.6	12.4	2.5	2.5	26.5	12.0	8.4	5.4	28.0	2.6	59.1	41.0	1.7	14.7	103.6	17.8	24.6	57.6	144.8	2.3	21.4	66.6	12.8	2.4	5.9	28.2	22.9	3.9	142.1	50.9	2.5	0.1	1.5	0.2	1.0	307.5	0.3	5.0	0.3	0.1	0.2	0.8	0.9	0.0	0.7	0.7	0.1	0.2	0.5	0.8	0.2	0.8	1.5	5.7	0.4	0.5	18.4	0.8	0.3	1.0	3.3	1.0	0.3	0.8	0.0	0.2	2.2	0.3	1.7	0.6	0.2	0.2	1.4	0.7	0.1	0.4	0.7	0.8	3.0	0.1	2.2	0.3	0.4	0.0	0.2	2.0	2.2	0.1	0.1	0.0	0.3	2.7	1.2	0.4	4.8	5.9	0.6	0.4	2.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	2.6	3.2	2.5	4.2	2.9	2.5	2.5	2.5	2.6	2.3	2.4	2.5	58.2	3.2	6.0	0.0	0.5	2.9	0.1	0.0	2.2	0.0	1.1	2.2	9.5	0.0	1.9	0.0	0.0	0.1	0.4	0.1	0.0	0.2	4.5	0.8	2.3	12.3	0.0	0.0	0.4	0.2	0.1	11.3	0.0	1.4	1.3	2.1	20.7	0.2	1.4	0.0	0.3	0.1	0.0	1.4	2.7	2.6	3.4	0.9	3.6	3.7	0.0	0.2	0.0	0.0	0.1	0.2	0.0	74.9	0.0	0.4	0.1	1.4	1.0	0.4	118.3	2.6	93.0	1.1	1.3	0.7	1.8	0.3	0.6	74.6	0.1	0.3
AOX1	"AO, AOH1"	ENSG00000138356	"Aldehyde oxidase 1"	Q06278	2	200586014-200677064	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"adrenal gland: 300.5;liver: 891.0"	"Cell type enriched"	"Detected in many"	4	"Hepatocytes: 749.1"	"Cancer enriched"	"Detected in many"	9	"liver cancer: 122.5"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"ASC diff: 377.3;ASC TERT1: 191.5;HSkMC: 78.2;hTERT-HME1: 81.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA040199, HPA040215"	Enhanced					NA	NA		3300000		"Cluster 85: Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 2: Hepatocytes - Metabolism"			"HPA040199: AB_10795273, HPA040215: AB_10795360"	"unprognostic (4.39e-2)"	"unprognostic (1.03e-3)"	"unprognostic (1.96e-1)"	"unprognostic (3.15e-2)"	"unprognostic (1.17e-4)"	"unprognostic (1.92e-2)"	"unprognostic (2.34e-2)"	"unprognostic (3.54e-1)"	"unprognostic (1.15e-1)"	"unprognostic (4.93e-2)"	"unprognostic (5.48e-2)"	"unprognostic (2.00e-2)"	"prognostic favorable (6.05e-5)"	"unprognostic (1.33e-2)"	"unprognostic (8.16e-3)"	"unprognostic (3.38e-2)"	"unprognostic (4.99e-3)"	87.6	300.5	0.6	3.2	2.9	0.5	50.2	0.1	2.4	17.9	3.6	12.0	0.8	10.8	12.3	8.2	48.2	9.9	14.9	1.1	1.5	103.2	891.0	19.5	4.7	1.3	1.0	48.0	85.0	1.3	2.8	1.7	1.2	22.3	4.5	0.5	15.3	28.3	12.9	20.1	12.7	7.1	0.5	4.1	14.3	19.4	4.0	2.0	17.7	11.0	1.5	38.6	17.7	3.6	0.6	0.2	0.0	0.0	377.3	191.5	0.2	6.6	12.2	5.4	9.7	0.0	0.1	0.1	0.5	8.4	2.3	0.2	0.1	18.6	22.0	0.2	0.6	0.0	4.6	20.7	25.4	0.9	0.0	78.2	4.6	26.1	81.2	5.4	0.2	0.2	0.2	0.1	18.3	0.5	0.0	0.1	8.0	0.1	5.2	0.0	0.5	0.1	0.2	0.2	0.4	0.3	4.8	0.0	0.3	0.4	0.1	0.2	31.9	13.8	11.2	0.2	2.5	0.2	0.1	2.6	10.7	0.5	1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	2.9	0.1	2.4	1.1	1.5	1.3	1.0	1.2	0.5	4.0	3.6	1.0	3.2	1.1	0.7	3.6	1.8	0.5	1.2	1.2	0.1	0.2	0.3	0.9	17.2	0.1	3.7	0.0	0.1	0.0	0.1	11.7	0.7	0.8	0.4	3.0	2.6	3.0	37.5	0.9	26.2	0.2	22.9	0.0	8.2	0.0	0.1	15.4	749.1	0.4	0.0	2.5	0.1	2.0	19.8	3.6	4.4	74.0	1.7	3.6	1.0	0.0	0.6	0.0	5.0	6.9	11.5	0.0	82.0	0.0	7.5	0.1	162.2	0.1	0.1	0.0	5.3	3.0	0.8	1.3	0.1	1.6	0.0	2.0	2.3	0.1	0.4
ASPDH		ENSG00000204653	"Aspartate dehydrogenase domain containing"	A6ND91	19	50511600-50514690	"Enzymes, Predicted intracellular proteins"	"Pyridine nucleotide biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 40.1;kidney: 39.0;liver: 132.4"	"Group enriched"	"Detected in some"	6	"Hepatocytes: 135.8;Proximal tubular cells: 487.2"	"Cancer enriched"	"Detected in some"	13	"liver cancer: 24.2"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HEK 293: 13.6;MOLT-4: 16.5;SH-SY5Y: 9.2"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA042631, HPA042654"	Approved		Approved	Nucleoplasm,Cytosol		NA	NA		200000		"Cluster 15: Liver - Metabolism"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Nucleoplasm	Cytosol	"HPA042631: AB_10794530, HPA042654: AB_10794383"	"unprognostic (5.79e-2)"	"unprognostic (9.47e-2)"	"unprognostic (8.97e-3)"	"unprognostic (6.13e-3)"	"unprognostic (5.13e-1)"	"unprognostic (3.64e-2)"	"unprognostic (3.15e-3)"	"unprognostic (3.32e-2)"	"unprognostic (2.87e-2)"	"unprognostic (2.09e-2)"	"unprognostic (2.87e-3)"	"unprognostic (6.70e-3)"	"unprognostic (9.65e-3)"	"unprognostic (3.36e-2)"	"unprognostic (1.07e-1)"	"unprognostic (5.31e-4)"	"unprognostic (1.99e-3)"	0.5	2.5	18.1	0.9	20.9	0.5	0.0	23.7	40.1	0.0	7.3	0.2	6.6	0.2	0.0	0.3	0.0	1.7	0.3	19.8	17.3	39.0	132.4	0.2	0.9	17.0	17.5	0.0	0.8	0.0	19.6	0.0	16.8	0.3	0.0	5.4	1.6	0.0	0.3	1.1	2.5	0.0	13.4	0.6	0.3	0.2	22.9	2.4	0.9	0.0	0.0	0.1	0.1	21.9	0.1	2.2	0.0	0.1	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.2	0.7	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.3	13.6	0.0	0.7	3.8	0.0	1.1	1.3	0.0	0.0	0.0	0.0	0.0	0.0	1.6	0.4	1.7	0.0	1.6	16.5	0.1	0.0	0.6	0.2	0.4	0.3	1.1	0.0	0.2	1.7	9.2	0.0	0.0	0.7	0.0	0.0	0.0	0.3	0.0	0.6	0.0	0.0	3.6	0.8	1.8	0.2	2.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	18.1	20.9	23.7	40.1	19.8	17.3	17.0	17.5	16.8	13.4	22.9	21.9	0.0	0.0	0.0	3.3	2.0	0.0	0.0	0.0	0.0	29.8	0.0	0.0	0.4	1.5	0.0	9.2	4.2	0.0	0.0	0.1	45.0	0.0	0.7	0.0	0.0	0.1	7.1	10.7	4.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.8	135.8	0.0	0.0	4.4	0.1	0.0	1.9	0.0	2.5	0.0	3.4	0.0	2.8	0.0	0.7	0.0	0.0	3.3	0.0	0.0	0.0	0.0	0.0	8.8	487.2	0.0	4.4	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	1.1	0.0	0.1	0.0
ASPH	"BAH, CASQ2BP1, HAAH, JCTN"	ENSG00000198363	"Aspartate beta-hydroxylase"	Q12797	8	61500556-61714640	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"		"Dioxygenase, Oxidoreductase"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adipose tissue: 386.9"	"Cell type enhanced"	"Detected in all"		"Muller glia cells: 468.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"plasmacytoid DC: 34.0"	"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"U-87 MG: 890.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA055161, HPA059303"	Uncertain		Enhanced	"Endoplasmic reticulum"		NA	NA		1100000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 20: HeLa - Mitochondria"	"Cluster 5: Muller glia cells - Visual perception"	"Endoplasmic reticulum"		"HPA055161: AB_2682721, HPA059303: AB_2683973"	"unprognostic (8.07e-2)"	"prognostic unfavorable (8.07e-5)"	"unprognostic (1.73e-2)"	"unprognostic (4.48e-2)"	"unprognostic (2.32e-1)"	"unprognostic (1.85e-2)"	"unprognostic (2.82e-2)"	"prognostic unfavorable (3.61e-4)"	"unprognostic (6.39e-2)"	"unprognostic (3.64e-1)"	"prognostic unfavorable (1.75e-4)"	"unprognostic (9.50e-2)"	"prognostic unfavorable (1.57e-5)"	"unprognostic (8.96e-2)"	"unprognostic (1.65e-1)"	"prognostic unfavorable (4.24e-4)"	"unprognostic (2.74e-2)"	386.9	160.3	64.7	50.6	69.2	16.9	106.9	102.3	88.9	65.6	84.4	78.8	45.6	49.3	44.7	71.4	46.9	61.0	111.3	64.5	58.4	59.5	74.9	74.1	20.3	54.0	69.2	62.2	44.7	38.7	36.3	47.9	52.2	48.3	84.9	219.5	101.9	70.2	357.6	35.2	45.5	67.5	44.8	28.6	105.0	16.5	71.8	16.7	97.0	182.7	28.5	112.2	43.8	60.4	460.3	652.3	89.9	55.1	392.1	370.1	31.2	804.0	741.3	336.3	350.1	113.1	594.2	35.3	54.3	474.6	270.3	167.5	56.2	281.1	570.0	13.6	57.0	81.1	372.5	310.3	251.2	12.5	12.9	306.5	61.9	187.6	237.4	657.2	144.8	18.0	22.2	32.1	300.2	97.4	3.3	16.6	51.7	441.6	383.4	22.3	97.0	7.3	206.2	374.0	93.1	32.1	249.9	116.1	101.7	49.0	47.7	22.2	456.7	338.0	174.3	313.0	288.0	20.2	27.1	1.5	890.1	7.5	231.4	1.9	8.3	0.3	2.5	2.9	4.7	5.5	3.5	2.4	10.0	5.0	4.9	2.5	25.4	8.7	1.8	34.0	4.0	4.1	64.7	69.2	102.3	88.9	64.5	58.4	54.0	69.2	52.2	44.8	71.8	60.4	79.1	195.5	244.0	366.6	13.8	47.0	160.7	126.0	68.9	138.3	83.7	58.4	228.6	37.1	157.5	86.5	294.0	118.1	40.3	57.0	15.6	144.2	1.6	51.4	65.8	85.9	116.5	13.0	93.1	180.4	107.1	132.0	73.9	115.4	8.2	34.5	42.8	62.6	72.2	127.9	98.9	215.1	52.9	26.6	44.1	3.1	70.8	48.1	42.7	61.8	20.0	468.8	2.1	154.8	53.5	257.7	32.3	57.6	15.9	148.2	34.3	34.6	66.6	158.8	46.0	114.4	92.7	3.4	16.8	101.7	50.3	48.0	13.6	131.2	67.3	254.2
BBOX1	"BBH, BBOX, G-BBH, gamma-BBH"	ENSG00000129151	"Gamma-butyrobetaine hydroxylase 1"	O75936	11	27040725-27127809	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Carnitine biosynthesis"	"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"kidney: 467.9;liver: 131.9"	"Cell type enriched"	"Detected in many"	7	"Proximal tubular cells: 1623.0"	"Group enriched"	"Detected in many"	6	"glioma: 23.7;renal cancer: 59.4"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	4	"hTCEpi: 13.7;RPTEC TERT1: 7.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA007600, HPA027823"	Enhanced	Approved	Uncertain	"Vesicles,Actin filaments"		NA	NA		35000		"Cluster 7: Kidney - Transmembrane transport"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Vesicles	"Actin filaments"	"HPA007600: AB_1845284, HPA027823: AB_10602394"	"unprognostic (9.96e-3)"	"unprognostic (1.80e-2)"	"unprognostic (8.17e-2)"	"prognostic unfavorable (6.65e-4)"	"unprognostic (7.03e-2)"	"unprognostic (6.66e-2)"	"unprognostic (7.05e-3)"	"unprognostic (1.13e-2)"	"unprognostic (3.03e-1)"	"unprognostic (6.89e-2)"	"unprognostic (2.03e-2)"	"unprognostic (1.60e-1)"	"prognostic favorable (1.45e-5)"	"unprognostic (1.71e-2)"	"unprognostic (2.70e-1)"	"unprognostic (3.22e-1)"	"unprognostic (1.73e-3)"	1.4	0.0	24.3	0.0	23.4	0.0	25.1	28.8	34.0	5.1	17.3	0.2	0.0	0.1	8.1	17.5	9.0	9.6	0.0	22.8	25.6	467.9	131.9	0.3	0.1	27.2	33.1	0.0	0.8	0.0	6.9	0.3	35.0	0.5	0.0	0.4	6.1	4.1	0.9	51.8	0.0	0.0	28.8	0.0	0.2	0.1	25.2	1.1	9.6	0.0	0.6	0.1	11.3	27.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.9	13.7	0.0	0.0	2.6	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	7.5	0.0	0.0	0.0	0.2	2.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	24.3	23.4	28.8	34.0	22.8	25.6	27.2	33.1	35.0	28.8	25.2	27.0	0.1	0.0	0.6	66.3	5.3	8.2	9.0	80.9	0.6	0.0	16.3	11.0	0.0	15.7	18.1	46.0	0.0	0.3	0.2	0.0	223.0	0.7	1.1	10.3	0.1	0.3	0.0	0.0	1.1	0.0	0.0	0.4	0.0	0.9	0.0	0.1	0.4	27.9	0.0	0.0	0.8	0.0	12.2	0.6	1.1	1.1	0.0	7.1	1.8	4.7	0.0	13.8	0.0	2.0	0.3	0.1	0.0	0.4	0.0	0.2	0.0	1623.0	9.4	0.4	0.0	0.0	1.4	0.0	0.6	16.9	35.8	0.3	5.0	0.0	0.0	2.6
BCKDHA	"MSU, OVD1A"	ENSG00000248098	"Branched chain keto acid dehydrogenase E1 subunit alpha"	P12694	19	41397808-41425002	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, Maple syrup urine disease"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Basal squamous epithelial cells: 26.2;Gastric mucus-secreting cells: 23.4;Plasma cells: 25.0;Squamous epithelial cells: 27.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							HPA036640	Supported					NA	NA		7700	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 29: U-266 - Adaptive immune response"	"Cluster 59: Non-specific - Transcription"			"HPA036640: AB_10671964"	"unprognostic (4.50e-2)"	"unprognostic (6.85e-2)"	"unprognostic (1.14e-1)"	"unprognostic (8.58e-3)"	"unprognostic (1.26e-2)"	"prognostic favorable (9.37e-4)"	"unprognostic (2.41e-2)"	"unprognostic (8.55e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.48e-2)"	"unprognostic (1.12e-2)"	"unprognostic (1.53e-1)"	"prognostic favorable (5.33e-10)"	"unprognostic (1.73e-1)"	"unprognostic (1.37e-1)"	"prognostic unfavorable (3.27e-5)"	"unprognostic (9.66e-2)"	33.8	78.4	32.0	19.3	35.5	32.4	25.2	37.0	39.3	24.6	37.0	20.9	19.9	17.9	14.1	65.1	28.8	15.4	90.4	32.5	35.1	44.3	110.0	22.4	24.5	34.4	33.8	25.4	46.1	56.3	24.0	19.0	36.2	23.8	15.0	21.7	40.9	23.1	110.0	31.8	18.7	12.7	33.9	24.4	52.5	27.1	35.7	27.0	41.7	122.0	21.2	21.7	31.9	40.0	42.7	75.1	14.2	44.1	22.2	12.8	17.1	11.9	25.3	24.4	29.9	18.2	36.0	34.6	23.7	15.1	11.0	17.1	15.0	25.9	12.1	36.0	41.0	27.1	35.2	21.3	51.5	25.5	17.7	27.6	37.6	16.9	38.2	36.0	45.0	50.9	25.9	68.9	17.6	41.5	28.0	20.0	12.8	61.1	21.1	27.1	22.8	89.6	29.8	19.8	32.5	38.6	39.6	84.7	34.1	12.1	45.4	81.0	29.3	22.2	23.0	12.0	22.0	131.9	55.1	34.1	81.8	56.6	24.6	61.4	149.4	59.7	49.5	123.9	56.7	46.0	47.0	49.1	154.6	49.5	43.2	44.9	46.4	82.4	95.5	62.6	63.9	125.6	32.0	35.5	37.0	39.3	32.5	35.1	34.4	33.8	36.2	33.9	35.7	40.0	0.6	0.0	13.1	4.9	10.0	0.3	0.1	2.6	26.2	0.2	1.5	0.4	0.1	1.5	5.3	5.5	0.0	1.9	0.9	3.8	3.9	14.7	0.7	0.5	0.6	2.4	6.1	15.5	5.8	11.8	1.7	3.7	23.4	0.7	5.1	0.4	2.5	2.4	2.7	0.0	6.2	7.6	8.2	2.2	0.8	0.9	0.6	6.6	3.6	3.7	12.4	0.4	5.2	4.0	5.7	8.4	3.8	0.4	25.0	0.2	6.7	2.3	1.2	1.2	0.0	0.2	3.6	1.8	0.9	27.2	0.9	2.1	6.3	0.3	7.3	0.1
BCKDHB		ENSG00000083123	"Branched chain keto acid dehydrogenase E1 subunit beta"	P21953	6	80106647-80346270	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, Maple syrup urine disease"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 78.4"	"Cell type enhanced"	"Detected in all"		"Astrocytes: 296.5;Early spermatids: 110.9;Inhibitory neurons: 94.9;Oligodendrocyte precursor cells: 98.5;Oligodendrocytes: 101.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA031580, HPA031956"	Approved		Supported	Nucleoplasm,Nucleoli,Mitochondria	"Intracellular and membrane"	Yes	No			"Cluster 15: NK-cells - Transcription"	"Cluster 85: Liver - Metabolism"	"Cluster 32: U-937 - Innate immune response"	"Cluster 64: Astrocytes - Nervous system maintenance"	Mitochondria	"Nucleoplasm, Nucleoli"	"HPA031580: AB_10696054, HPA031956: "	"unprognostic (4.23e-1)"	"unprognostic (1.61e-1)"	"unprognostic (9.50e-3)"	"unprognostic (9.37e-3)"	"unprognostic (1.66e-1)"	"unprognostic (6.03e-2)"	"unprognostic (6.84e-3)"	"unprognostic (2.30e-2)"	"unprognostic (1.94e-1)"	"unprognostic (7.32e-3)"	"unprognostic (2.67e-1)"	"unprognostic (4.65e-2)"	"prognostic favorable (5.54e-9)"	"unprognostic (2.67e-1)"	"unprognostic (1.12e-1)"	"unprognostic (8.02e-2)"	"unprognostic (1.49e-2)"	19.7	10.7	7.3	7.6	8.3	8.2	22.3	11.5	7.8	11.7	11.6	22.5	11.5	9.2	7.1	10.3	11.5	7.8	18.8	8.8	7.0	31.8	78.4	7.3	8.8	10.7	9.2	14.6	12.9	19.7	7.2	4.8	13.1	15.9	20.7	7.9	26.6	11.3	10.9	8.5	12.4	9.4	11.8	6.3	17.6	13.1	8.7	9.1	15.5	15.3	9.1	11.2	7.6	16.0	13.8	5.1	18.8	25.3	18.6	16.1	14.9	9.7	19.8	15.4	21.0	8.3	18.5	38.9	10.1	23.1	18.0	13.6	10.6	12.7	21.5	48.8	15.6	19.4	12.6	11.3	20.7	27.7	8.3	15.6	12.8	10.7	13.3	13.8	18.6	29.8	16.6	33.8	35.0	7.6	10.3	16.3	14.0	30.1	6.5	25.5	58.3	33.8	43.2	20.7	12.6	17.8	16.2	13.4	9.9	20.6	17.3	21.1	8.0	9.2	6.3	8.5	13.0	24.0	25.2	12.9	11.3	20.4	14.2	3.4	4.2	1.0	10.1	5.1	13.3	10.6	8.3	8.5	8.3	12.7	11.0	11.6	0.8	17.4	5.9	12.9	20.3	6.1	7.3	8.3	11.5	7.8	8.8	7.0	10.7	9.2	13.1	11.8	8.7	16.0	8.4	9.6	21.0	296.5	11.5	8.5	12.5	21.1	15.9	7.8	19.6	14.7	29.3	8.6	18.0	5.5	2.1	17.0	9.1	17.5	27.4	8.2	110.9	8.3	10.3	8.0	12.0	10.3	72.0	10.4	8.3	13.7	15.3	17.6	16.5	19.2	11.0	66.5	12.2	3.3	94.9	31.3	10.2	9.1	9.0	13.7	8.7	5.4	16.0	59.0	7.3	15.5	10.3	98.5	101.7	5.4	10.4	8.6	8.4	6.2	11.5	33.1	13.5	8.7	6.6	11.1	9.4	15.2	5.6	20.1	12.4	10.4	9.9	15.5	17.4	10.9
BCO1	"BCDO, BCDO1, BCMO, BCMO1, FLJ10730"	ENSG00000135697	"Beta-carotene oxygenase 1"	Q9HAY6	16	81238689-81291142	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"choroid plexus: 5.0;intestine: 14.6"	"Cell type enhanced"	"Detected in some"		"Astrocytes: 6.2;Distal enterocytes: 4.8;Excitatory neurons: 8.0;Intestinal goblet cells: 5.5;Proximal enterocytes: 13.6;Proximal tubular cells: 8.8"	"Cancer enhanced"	"Detected in many"		"renal cancer: 3.4"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"A549: 11.5;EFO-21: 8.7;HAP1: 3.3;NTERA-2: 4.6;RPTEC TERT1: 8.6"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			HPA043811			Uncertain	"Actin filaments,Centriolar satellite"		NA	NA				"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	"Actin filaments, Centriolar satellite"		"HPA043811: AB_10962487"	"unprognostic (2.78e-1)"	"unprognostic (3.88e-3)"	"unprognostic (2.61e-1)"	"unprognostic (3.32e-1)"	"unprognostic (4.05e-2)"	"unprognostic (8.01e-4)"	"unprognostic (1.65e-1)"	"unprognostic (2.99e-2)"	"unprognostic (1.58e-3)"	"unprognostic (7.26e-2)"	"unprognostic (2.97e-2)"	"unprognostic (1.08e-3)"	"unprognostic (1.46e-1)"	"unprognostic (1.90e-2)"	"unprognostic (2.48e-1)"	"unprognostic (5.07e-2)"	"unprognostic (1.09e-1)"	0.0	0.0	1.8	0.2	1.3	0.0	0.1	0.0	1.2	0.2	5.0	2.6	9.3	0.6	0.2	0.3	0.4	1.2	0.0	2.5	0.2	3.5	0.8	0.2	0.0	0.4	0.4	0.9	0.3	0.0	0.7	0.0	0.1	0.5	3.0	0.2	0.5	1.5	0.1	0.3	14.6	0.3	0.1	0.0	1.9	0.1	0.7	0.2	0.1	0.0	0.0	0.2	0.4	0.6	0.0	11.5	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.2	0.3	2.3	0.0	8.7	0.0	0.3	0.1	3.3	0.0	0.0	0.1	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	4.6	0.8	0.0	0.0	0.0	0.0	8.6	0.3	0.3	0.0	0.0	0.4	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.8	1.3	0.0	1.2	2.5	0.2	0.4	0.4	0.1	0.1	0.7	0.6	0.0	0.0	0.0	6.2	0.0	0.0	0.3	0.0	0.6	0.0	0.1	0.0	0.2	0.0	0.0	1.8	0.0	0.5	0.0	4.8	0.0	0.6	0.1	0.9	1.1	0.1	1.2	0.0	8.0	0.0	0.0	0.2	0.0	4.0	0.0	0.1	0.4	0.3	0.1	0.0	3.7	5.5	0.0	0.0	0.0	0.3	1.5	0.1	0.0	1.0	0.0	0.0	0.0	2.5	1.0	0.6	2.1	1.2	0.0	0.1	13.6	8.8	0.0	0.0	0.0	0.1	0.1	0.4	0.2	0.7	0.0	0.3	0.1	0.0	3.0	0.7
BCO2	"B-DIOX-II, BCDO2, FLJ34464"	ENSG00000197580	"Beta-carotene oxygenase 2"	Q9BYV7	11	112175510-112224699	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 47.2;liver: 52.3;retina: 55.9"	"Cell type enhanced"	"Detected in many"		"Cone photoreceptor cells: 410.8;Horizontal cells: 134.6;Rod photoreceptor cells: 254.6"	"Low cancer specificity"	"Detected in some"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"CAPAN-2: 5.9;HHSteC: 12.3;U-937: 2.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA061542	Supported					NA	NA			"Cluster 22: NK-cells - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 9: Photoreceptor cells - Phototransduction"			"HPA061542: "	"unprognostic (2.92e-1)"	"unprognostic (1.89e-1)"	"unprognostic (3.76e-2)"	"unprognostic (1.40e-1)"	"unprognostic (1.91e-1)"	"unprognostic (1.50e-2)"	"unprognostic (7.60e-3)"	"unprognostic (1.88e-1)"	"unprognostic (3.18e-2)"	"unprognostic (6.40e-2)"	"unprognostic (2.39e-2)"	"unprognostic (6.91e-2)"	"unprognostic (1.36e-4)"	"unprognostic (2.31e-2)"	"unprognostic (9.86e-2)"	"unprognostic (1.07e-2)"	"unprognostic (1.34e-1)"	3.8	21.3	4.9	0.3	5.8	0.2	0.8	5.0	9.3	2.2	10.0	2.6	0.5	1.6	1.0	3.4	9.7	5.1	47.2	4.8	6.4	2.5	52.3	1.7	0.4	7.4	6.7	1.3	1.1	0.3	4.4	3.8	7.0	1.9	0.5	55.9	0.9	0.9	21.4	1.1	1.7	1.1	5.9	1.1	0.9	3.0	6.5	0.3	2.5	14.3	0.8	2.3	4.6	8.3	0.1	1.0	0.4	0.6	0.4	0.4	0.0	0.3	0.2	0.1	0.5	0.0	5.9	0.4	0.5	0.6	0.6	1.2	0.0	0.2	0.4	0.1	0.1	0.7	0.5	0.4	12.3	0.4	0.2	0.1	2.3	0.1	0.3	1.1	0.0	0.1	0.1	0.3	0.1	0.0	0.5	1.3	0.1	0.6	0.2	0.3	0.1	0.2	0.2	0.2	0.5	0.2	0.4	0.2	0.0	0.1	0.3	0.2	0.0	0.1	0.2	0.1	0.1	0.1	0.0	0.3	0.0	2.6	0.4	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.6	0.1	0.0	0.0	0.0	4.9	5.8	5.0	9.3	4.8	6.4	7.4	6.7	7.0	5.9	6.5	8.3	1.7	3.2	3.1	10.1	2.0	3.3	20.3	8.6	6.8	12.6	2.2	1.5	51.3	58.6	8.2	5.5	410.8	0.3	4.4	5.0	0.0	3.7	3.1	26.5	3.0	4.5	8.3	0.0	50.7	2.1	0.4	16.3	1.1	1.2	5.7	4.0	16.4	83.1	1.0	134.6	51.5	1.6	2.0	2.8	3.8	2.4	4.1	7.9	1.8	47.8	3.7	13.9	7.2	7.1	51.3	1.6	2.6	3.8	1.2	10.3	18.2	1.3	67.6	254.6	0.0	5.0	3.8	8.3	2.5	1.8	3.1	0.7	5.2	6.8	3.5	8.7
BDH1	"BDH, SDR9C1"	ENSG00000161267	"3-hydroxybutyrate dehydrogenase 1"	Q02338	3	197509783-197573323	"Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Allosteric enzyme, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	6	"liver: 324.0"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 112.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"OE19: 44.2;U-937: 75.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA030947, HPA058709"	Enhanced		Approved	Mitochondria		NA	NA			"Cluster 30: Non-specific - Translation"	"Cluster 85: Liver - Metabolism"	"Cluster 32: U-937 - Innate immune response"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Mitochondria		"HPA030947: AB_10669548, HPA058709: AB_2683797"	"unprognostic (2.72e-2)"	"prognostic favorable (1.09e-4)"	"unprognostic (1.13e-1)"	"unprognostic (3.93e-1)"	"unprognostic (3.35e-2)"	"unprognostic (1.07e-1)"	"prognostic favorable (9.86e-7)"	"unprognostic (2.08e-1)"	"unprognostic (3.85e-2)"	"unprognostic (4.53e-2)"	"unprognostic (5.17e-3)"	"unprognostic (5.85e-3)"	"prognostic favorable (7.12e-8)"	"unprognostic (5.62e-2)"	"unprognostic (1.74e-1)"	"unprognostic (6.22e-2)"	"unprognostic (1.02e-1)"	9.6	6.8	14.4	4.1	17.9	7.3	9.7	18.4	19.8	6.8	30.8	45.1	17.4	6.3	3.9	48.0	9.7	3.8	52.4	16.5	14.3	19.2	324.0	5.2	3.9	14.3	13.8	8.2	7.0	15.5	12.6	0.3	14.4	16.2	19.8	9.3	25.3	4.1	21.5	30.4	28.1	2.2	12.9	7.9	16.6	4.5	16.3	6.1	17.7	22.8	7.1	9.9	14.7	14.2	23.7	2.9	1.2	11.3	1.9	0.1	0.0	2.8	2.2	11.4	6.3	20.5	7.5	0.2	33.0	0.7	0.9	10.3	10.0	5.4	4.2	0.3	0.0	12.0	8.3	7.0	8.3	27.0	12.3	3.4	6.0	4.4	9.4	1.2	2.8	13.7	0.0	8.4	0.2	40.9	20.5	18.8	8.2	44.2	4.2	19.6	4.1	31.5	12.3	9.9	20.1	8.8	8.2	1.1	4.5	0.5	26.3	22.7	0.3	0.7	3.9	0.1	21.6	10.4	20.5	0.3	0.7	75.8	1.5	2.9	1.3	0.6	4.6	0.2	6.4	5.1	5.1	4.2	3.5	4.6	7.6	4.7	0.0	4.5	0.2	3.8	3.7	3.4	14.4	17.9	18.4	19.8	16.5	14.3	14.3	13.8	14.4	12.9	16.3	14.2	0.4	3.2	9.4	27.7	7.0	9.3	8.5	10.0	16.5	21.3	20.3	14.7	36.7	17.2	13.8	12.9	20.9	2.0	7.1	68.9	52.8	6.6	9.5	34.1	3.6	2.2	27.2	6.7	60.5	5.6	5.1	2.8	17.3	16.5	1.3	6.6	5.0	112.3	8.9	18.5	58.0	43.2	10.2	5.4	8.5	13.9	5.6	3.5	16.0	8.4	1.0	17.5	11.3	27.2	12.5	3.0	36.4	4.1	5.4	6.5	62.8	30.2	48.0	33.6	0.0	2.4	3.7	16.8	4.9	36.3	10.9	1.9	8.5	10.0	68.7	13.1
BDH2	"DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308"	ENSG00000164039	"3-hydroxybutyrate dehydrogenase 2"	Q9BUT1	4	103077592-103099870	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"kidney: 162.1"	"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 211.3;Proximal tubular cells: 795.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"RPTEC TERT1: 46.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA036028, HPA036029"	Enhanced		Supported	Cytosol		NA	NA			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Cytosol		"HPA036028: AB_10670674, HPA036029: AB_2674909"	"unprognostic (2.12e-2)"	"unprognostic (1.91e-1)"	"unprognostic (1.64e-1)"	"prognostic favorable (5.21e-4)"	"unprognostic (3.92e-1)"	"unprognostic (2.28e-1)"	"unprognostic (3.82e-2)"	"prognostic favorable (1.20e-4)"	"unprognostic (1.71e-1)"	"unprognostic (2.04e-1)"	"unprognostic (4.37e-1)"	"unprognostic (1.95e-1)"	"prognostic favorable (4.45e-13)"	"unprognostic (2.54e-2)"	"unprognostic (1.60e-1)"	"prognostic favorable (7.75e-4)"	"unprognostic (9.69e-3)"	45.0	96.6	23.3	4.3	25.8	3.5	39.7	27.0	27.3	46.6	27.1	31.8	39.4	31.2	16.6	27.2	43.4	14.9	46.6	20.3	27.8	162.1	70.5	35.9	6.7	28.4	26.5	54.8	23.2	30.8	29.2	7.7	27.0	31.9	10.3	8.5	32.8	14.1	24.6	26.1	39.6	9.6	25.2	21.2	38.9	14.8	28.2	17.5	62.9	16.7	7.3	37.1	37.3	26.5	3.1	5.3	26.5	10.0	30.4	29.4	3.4	6.7	17.8	6.9	10.6	3.4	11.8	12.4	11.1	10.2	2.1	1.5	17.3	10.1	8.2	8.2	8.5	1.5	6.4	8.1	15.0	7.4	2.1	24.8	9.1	10.6	2.6	23.0	20.7	14.3	8.0	5.5	24.1	1.0	37.2	6.3	9.6	2.0	2.1	24.5	30.7	7.9	46.4	3.6	4.5	12.0	12.8	6.7	7.9	9.6	5.7	5.3	9.9	10.7	3.4	5.5	3.7	8.1	7.9	12.5	11.8	8.9	5.4	2.6	2.5	0.2	7.6	1.4	8.8	4.8	6.6	6.0	3.2	6.7	9.8	10.4	0.4	6.5	0.2	5.0	10.2	4.0	23.3	25.8	27.0	27.3	20.3	27.8	28.4	26.5	27.0	25.2	28.2	26.5	37.7	32.1	57.8	33.6	10.2	30.3	47.1	59.4	36.5	2.5	31.9	36.1	9.6	64.3	46.9	108.5	0.0	7.9	19.0	18.0	211.3	58.2	1.9	60.6	45.5	30.3	22.9	16.4	1.2	21.3	18.5	75.2	41.8	27.9	19.6	39.1	27.8	71.6	20.4	3.3	3.8	24.4	46.8	10.9	16.9	4.8	69.9	12.5	23.2	14.0	14.9	50.4	14.4	3.5	21.8	23.0	18.6	77.8	8.0	18.9	162.3	795.7	48.7	3.8	13.1	40.9	36.5	0.9	4.0	25.9	26.7	3.4	18.2	52.6	37.6	37.5
BLVRA	BLVR	ENSG00000106605	"Biliverdin reductase A"	P53004	7	43758680-43807342	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Hofbauer cells: 259.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019709, HPA042865, HPA054322"	Approved		Supported	Cytosol		NA	NA		1200000	"Cluster 7: Monocytes - Unknown function"	"Cluster 68: Epididymis - Unknown function"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 4: Macrophages - Innate immune response"	Cytosol		"HPA019709: AB_2670239, HPA042865: AB_10797024, HPA054322: AB_2682450"	"unprognostic (2.47e-2)"	"unprognostic (8.38e-3)"	"unprognostic (1.79e-2)"	"unprognostic (2.16e-3)"	"unprognostic (6.45e-3)"	"unprognostic (5.01e-2)"	"unprognostic (1.63e-2)"	"prognostic favorable (8.65e-4)"	"unprognostic (1.42e-1)"	"unprognostic (1.75e-2)"	"unprognostic (2.93e-1)"	"unprognostic (9.27e-2)"	"unprognostic (1.15e-2)"	"unprognostic (5.63e-3)"	"unprognostic (3.18e-1)"	"unprognostic (2.13e-3)"	"unprognostic (4.56e-2)"	53.2	28.0	31.4	39.7	33.4	65.6	49.9	32.0	40.1	44.3	31.4	61.4	12.5	38.5	129.9	67.5	40.9	33.4	52.7	32.3	34.7	41.3	14.6	62.7	58.6	34.1	33.6	46.6	23.5	54.9	26.2	28.9	34.2	38.4	19.8	25.4	36.5	46.0	59.7	33.4	27.7	54.1	33.1	82.0	35.3	13.1	34.0	43.0	31.3	69.3	52.6	43.5	40.4	32.0	48.6	92.2	26.2	110.5	55.0	72.7	1.3	32.3	99.3	54.0	65.4	22.2	28.3	0.3	60.6	51.5	190.7	62.1	82.1	81.7	46.2	227.3	56.8	104.1	86.6	138.1	139.5	11.8	37.5	49.9	135.7	57.2	37.8	108.5	92.7	51.1	70.2	55.7	41.4	52.5	37.0	6.3	35.9	11.0	104.7	80.4	45.6	261.4	121.1	26.6	34.0	104.4	65.9	65.1	55.2	46.2	146.7	77.7	57.0	49.3	53.9	21.8	56.0	74.7	63.2	0.2	80.8	46.9	78.4	51.1	291.9	169.2	39.1	374.9	36.7	26.9	75.7	64.9	135.4	17.0	39.7	31.0	26.5	22.4	368.4	20.1	82.2	208.5	31.4	33.4	32.0	40.1	32.3	34.7	34.1	33.6	34.2	33.1	34.0	32.0	22.0	60.9	85.0	7.5	10.7	29.1	64.2	102.4	34.1	18.0	29.6	36.1	59.4	17.2	75.7	35.0	2.1	9.7	9.3	0.3	56.7	52.6	0.7	31.6	20.2	27.3	0.0	74.7	8.4	35.1	8.1	39.7	8.2	41.4	111.5	17.2	24.3	1.9	259.1	8.4	11.5	0.4	59.0	136.5	53.7	1.6	37.0	80.4	46.2	2.8	147.3	36.6	13.4	7.5	4.3	25.2	1.2	29.0	16.6	87.9	7.1	110.5	69.6	13.0	46.0	23.0	50.6	3.0	14.2	52.9	34.4	5.2	23.4	4.9	0.6	48.7
BLVRB	"FLR, SDR43U1"	ENSG00000090013	"Biliverdin reductase B"	P30043	19	40447765-40465764	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 625.2"	"Cell type enhanced"	"Detected in all"		"Erythroid cells: 3131.8;Hofbauer cells: 1099.2;Proximal enterocytes: 864.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"classical monocyte: 465.2"	"Group enriched"	"Detected in all"	7	"dendritic cells: 343.3;monocytes: 465.2"	"Cell line enhanced"	"Detected in many"		"A549: 506.6;K-562: 506.8;OE19: 451.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041698, HPA041937"	Enhanced		Supported	"Nucleoplasm,Vesicles,Plasma membrane,Cytosol"		No	No		370000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 6: Erythroid cells - Oxygen transport"	Cytosol	"Nucleoplasm, Vesicles, Plasma membrane"	"HPA041698: AB_10796781, HPA041937: AB_10794308"	"unprognostic (1.86e-1)"	"unprognostic (1.14e-2)"	"unprognostic (4.23e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.08e-1)"	"unprognostic (2.46e-1)"	"unprognostic (9.92e-2)"	"unprognostic (1.20e-2)"	"unprognostic (8.56e-2)"	"unprognostic (1.35e-1)"	"prognostic unfavorable (3.90e-4)"	"unprognostic (2.30e-1)"	"unprognostic (2.70e-1)"	"unprognostic (2.02e-1)"	"unprognostic (5.11e-2)"	"unprognostic (1.25e-1)"	"unprognostic (3.92e-2)"	115.7	76.8	46.6	48.2	46.9	625.2	93.8	49.4	61.0	86.2	52.1	78.5	75.1	59.0	20.5	188.8	69.3	50.9	125.6	44.5	48.0	103.1	266.2	102.8	58.9	56.0	48.6	66.7	73.2	46.1	25.2	52.1	58.5	74.3	30.3	5.5	89.4	42.2	210.4	83.9	72.2	31.7	49.8	166.7	138.4	10.2	52.3	27.5	64.5	94.1	25.3	81.0	96.5	53.4	227.9	506.6	7.3	77.7	73.7	70.2	57.3	28.0	88.7	39.3	75.4	103.4	203.8	74.3	212.3	56.3	126.8	73.1	30.4	64.6	10.5	123.8	20.0	114.9	73.4	62.4	169.8	1.6	32.2	69.2	119.4	52.4	34.2	40.1	41.8	27.4	506.8	137.0	51.0	359.2	6.1	7.2	1.9	451.4	133.8	54.0	23.4	120.3	50.9	146.5	0.4	10.5	84.5	224.5	84.4	13.2	221.5	17.6	39.2	99.4	103.9	156.4	15.9	71.7	92.1	28.5	259.1	46.2	39.0	45.5	465.2	18.0	29.2	220.9	27.0	58.2	24.3	24.5	343.3	37.5	24.7	19.3	58.4	27.4	117.7	75.8	37.3	259.4	46.6	46.9	49.4	61.0	44.5	48.0	56.0	48.6	58.5	49.8	52.3	53.4	74.6	221.2	164.5	9.4	34.4	129.4	348.5	337.9	103.6	11.2	93.8	143.0	130.5	164.5	184.2	97.5	6.2	84.9	39.5	343.6	266.1	234.2	10.0	56.5	46.3	51.1	44.9	3131.8	5.2	267.3	94.7	112.5	280.3	83.1	43.1	31.0	57.1	680.8	1099.2	10.1	5.1	223.5	158.7	627.7	165.4	23.6	124.2	286.7	144.1	13.1	219.8	88.0	32.0	2.0	5.6	260.4	464.0	94.0	25.7	229.7	864.3	488.3	139.1	13.5	32.9	65.4	146.0	2.6	4.0	160.3	130.4	74.7	34.5	34.7	191.0	260.5
CAT		ENSG00000121691	Catalase	P04040	11	34438934-34472060	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Hydrogen peroxide"	"Mitogen, Oxidoreductase, Peroxidase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 1217.3"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 722.4;Hepatocytes: 443.4;Proximal tubular cells: 333.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in all"	13	"eosinophil: 4736.8"	"Lineage enriched"	"Detected in all"	13	"granulocytes: 4736.8"	"Cell line enhanced"	"Detected in many"		"HL-60: 391.4;THP-1: 321.2;U-937: 265.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB001515, HPA051282, HPA055838"	Enhanced		Enhanced	Vesicles		NA	NA		760000000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 85: Liver - Metabolism"	"Cluster 32: U-937 - Innate immune response"	"Cluster 6: Erythroid cells - Oxygen transport"	Vesicles		"CAB001515: AB_384710, HPA051282: AB_2681419, HPA055838: AB_2682937"	"unprognostic (3.62e-2)"	"unprognostic (2.72e-1)"	"unprognostic (3.59e-3)"	"unprognostic (5.43e-2)"	"unprognostic (4.44e-2)"	"unprognostic (5.80e-3)"	"prognostic favorable (9.67e-4)"	"unprognostic (9.95e-3)"	"unprognostic (3.22e-1)"	"unprognostic (7.23e-2)"	"unprognostic (3.34e-2)"	"unprognostic (9.77e-2)"	"prognostic favorable (1.96e-8)"	"unprognostic (1.01e-1)"	"unprognostic (7.31e-2)"	"unprognostic (4.77e-2)"	"unprognostic (6.59e-3)"	281.3	115.1	27.1	52.1	29.6	407.7	123.6	27.9	35.5	82.0	39.4	82.6	145.1	53.1	34.8	40.1	86.8	59.8	58.1	26.6	29.4	296.6	1217.3	163.2	58.4	35.2	29.4	46.7	86.3	43.2	13.6	78.0	34.3	66.8	71.3	9.8	83.7	64.0	103.8	70.6	136.3	59.4	29.6	78.6	74.1	11.4	29.5	74.9	122.6	136.6	56.7	105.8	39.9	40.8	31.7	34.3	24.5	38.9	233.2	100.6	52.3	39.3	49.8	43.3	47.1	19.7	30.9	78.3	37.5	79.2	63.9	73.9	42.3	42.9	47.3	68.8	38.8	65.6	34.0	113.7	27.6	391.4	31.1	54.5	29.3	13.2	5.1	59.9	53.2	46.2	139.3	31.3	55.1	30.2	81.1	77.4	0.1	148.7	82.6	56.5	117.9	64.9	120.2	117.2	13.1	19.8	44.5	70.6	60.0	0.0	101.4	321.2	38.3	25.9	24.9	65.4	23.8	25.0	15.2	16.8	51.3	265.6	19.3	256.5	324.7	4736.8	54.4	265.1	64.6	133.9	63.7	61.0	353.5	124.1	61.7	66.7	290.2	105.7	298.5	235.8	92.7	397.9	27.1	29.6	27.9	35.5	26.6	29.4	35.2	29.4	34.3	29.6	29.5	40.8	196.9	227.6	275.9	41.1	53.8	28.9	93.7	44.9	27.9	13.5	42.6	36.1	44.9	82.9	66.9	73.5	27.1	96.8	92.0	59.4	225.0	36.0	2.7	72.2	41.4	43.8	48.0	722.4	12.6	26.2	30.0	53.1	54.6	29.3	24.0	38.7	57.1	443.4	138.5	0.0	1.2	56.9	91.6	125.5	95.8	6.2	78.3	93.9	26.6	16.9	253.4	19.5	28.8	22.6	45.6	15.3	44.8	77.5	25.4	37.0	151.6	333.2	96.9	19.4	78.9	46.6	68.0	6.3	11.3	24.4	27.1	40.5	37.7	57.7	95.6	97.5
CBR1	"CBR, SDR21C1"	ENSG00000159228	"Carbonyl reductase 1"	P16152	21	36069941-36073166	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"intestine: 583.9"	"Cell type enhanced"	"Detected in all"		"Basal squamous epithelial cells: 524.2;Distal tubular cells: 757.2;Proximal enterocytes: 1270.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"HPA018433, CAB034291"	Enhanced		Approved	Nucleoplasm,Cytosol		NA	NA		12000000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 45: Intestine - Brush border"	"Cluster 16: U-266 - Nucleosome"	"Cluster 45: Enterocytes - Digestion"	Nucleoplasm	Cytosol	"CAB034291: AB_2070856, HPA018433: AB_1846109"	"prognostic favorable (2.18e-4)"	"unprognostic (9.78e-2)"	"unprognostic (3.25e-2)"	"unprognostic (2.14e-1)"	"unprognostic (6.47e-3)"	"unprognostic (1.69e-1)"	"unprognostic (1.19e-1)"	"unprognostic (6.37e-2)"	"unprognostic (4.56e-2)"	"unprognostic (1.28e-1)"	"unprognostic (7.20e-2)"	"unprognostic (4.00e-1)"	"prognostic favorable (4.75e-4)"	"unprognostic (2.37e-1)"	"unprognostic (2.47e-1)"	"unprognostic (6.13e-3)"	"unprognostic (2.47e-2)"	32.4	95.3	150.0	25.6	200.0	10.1	29.5	186.1	174.1	52.7	207.0	68.6	583.9	41.3	50.5	189.5	34.6	47.1	29.5	154.6	166.7	125.6	252.8	41.1	28.3	173.1	175.1	28.8	36.1	38.6	35.3	27.6	175.6	48.7	50.9	10.2	101.8	42.2	33.6	111.8	345.9	34.4	166.2	39.9	133.5	18.1	180.3	22.7	46.4	23.3	36.7	51.0	85.3	266.6	114.4	180.4	22.6	55.9	115.0	115.3	1.2	123.6	97.0	72.4	86.4	68.9	67.8	28.2	78.7	128.1	137.3	84.6	46.3	132.3	55.7	133.8	95.3	82.5	105.1	48.1	65.7	49.1	77.5	56.1	165.6	70.7	30.8	83.0	78.4	0.0	0.0	21.3	67.6	121.2	24.7	50.7	0.4	0.0	123.3	0.4	0.4	80.5	195.7	60.9	60.5	52.1	121.3	186.3	157.3	17.6	86.1	69.4	71.1	78.8	30.8	202.9	96.1	131.8	268.9	0.7	144.0	48.6	115.6	7.1	134.0	68.6	64.4	198.5	54.6	67.2	79.7	60.8	109.6	61.2	102.6	75.4	9.2	77.3	156.9	39.6	89.0	162.1	150.0	200.0	186.1	174.1	154.6	166.7	173.1	175.1	175.6	166.2	180.3	266.6	26.4	121.8	69.3	17.9	22.5	128.2	63.1	295.2	524.2	11.6	27.7	98.8	20.9	77.2	117.1	95.6	2.1	116.6	15.7	91.2	757.2	93.7	8.9	31.7	45.5	23.1	38.6	32.0	6.5	70.0	80.4	65.7	127.4	45.1	34.9	30.8	41.7	277.2	85.1	3.3	6.8	94.4	396.7	66.6	27.5	4.3	122.7	49.5	90.7	4.7	79.2	69.8	23.7	16.6	128.2	91.8	146.6	132.4	41.3	66.4	1270.3	326.0	121.2	8.3	26.3	51.3	90.7	5.8	17.4	403.5	123.6	89.2	30.7	55.6	145.8	55.0
CBR3	SDR21C2	ENSG00000159231	"Carbonyl reductase 3"	O75828	21	36135079-36146562	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 56.3;salivary gland: 41.4"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 102.5;Basal squamous epithelial cells: 107.0;Peritubular cells: 75.6;Squamous epithelial cells: 230.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Group enriched"	"Detected in many"	9	"B-cells: 23.9;NK-cells: 11.5;T-cells: 33.7"	"Cell line enhanced"	"Detected in many"		"RPMI-8226: 64.9"	"Region enhanced"	"Detected in all"		"basal ganglia: 48.6"	"Low region specificity"	"Detected in many"			HPA018434	Uncertain		Supported	Nucleoplasm,Cytosol		Yes	NA		2800000	"Cluster 30: Non-specific - Translation"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 61: Squamous epithelial cells - Keratinization"	"Nucleoplasm, Cytosol"		"HPA018434: AB_1846110"	"unprognostic (3.64e-3)"	"unprognostic (2.32e-2)"	"unprognostic (1.48e-1)"	"unprognostic (1.46e-1)"	"unprognostic (2.16e-1)"	"unprognostic (1.18e-3)"	"unprognostic (1.22e-1)"	"unprognostic (2.22e-2)"	"unprognostic (6.12e-2)"	"unprognostic (2.98e-2)"	"unprognostic (3.75e-1)"	"unprognostic (9.10e-2)"	"prognostic unfavorable (5.95e-6)"	"unprognostic (3.13e-1)"	"unprognostic (1.80e-1)"	"unprognostic (3.99e-3)"	"unprognostic (1.94e-1)"	17.3	2.3	12.8	4.0	14.7	1.4	15.3	13.9	19.8	12.4	11.2	7.8	3.0	7.5	11.0	56.3	8.8	6.5	6.1	13.2	12.4	2.7	0.8	4.6	2.9	12.8	12.1	11.2	1.6	0.6	2.4	2.9	12.3	9.9	3.6	0.6	41.4	5.1	3.1	21.6	5.4	6.1	12.0	3.1	5.2	3.1	12.2	2.0	4.6	7.8	7.6	11.6	16.8	12.4	33.5	9.5	4.0	8.2	31.0	47.8	5.9	35.4	42.4	40.6	32.1	0.4	6.9	0.0	10.2	37.2	13.7	15.0	5.5	7.2	16.2	45.3	17.2	1.4	10.0	0.3	2.6	0.1	0.1	6.8	0.8	28.1	3.6	19.1	24.9	3.7	0.0	0.3	12.1	25.4	3.1	14.7	3.2	10.3	41.5	6.7	7.6	64.9	13.7	14.2	2.1	2.9	27.3	32.6	53.3	2.2	9.8	3.9	17.1	25.7	2.2	28.8	35.0	1.5	0.6	0.0	26.9	0.9	47.3	0.0	0.6	0.1	2.2	0.5	3.0	23.6	25.1	7.7	2.4	23.9	33.7	23.5	0.9	11.5	1.0	0.7	10.9	11.5	12.8	14.7	13.9	19.8	13.2	12.4	12.8	12.1	12.3	12.0	12.2	12.4	41.7	0.0	3.2	6.8	5.2	71.0	22.1	102.5	107.0	0.8	23.1	38.6	0.2	2.8	23.0	0.0	0.0	1.2	2.9	1.9	9.8	4.7	0.7	13.1	7.5	26.5	0.0	1.7	3.9	0.7	0.3	53.4	7.7	14.7	5.7	1.1	14.3	0.3	8.4	0.0	5.5	12.6	69.2	3.8	41.3	4.0	67.7	5.8	65.8	2.8	20.9	1.9	0.0	1.5	0.5	2.6	1.7	75.6	1.4	43.4	1.3	0.2	13.1	0.6	0.0	21.4	19.7	0.4	0.2	230.4	46.7	0.3	7.0	1.0	8.1	21.1
CDO1		ENSG00000129596	"Cysteine dioxygenase type 1"	Q16878	5	115804733-115816659	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 506.7"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 329.4;Hepatocytes: 149.5;Leydig cells: 91.0;Syncytiotrophoblasts: 481.9;Theca cells: 104.7"	"Group enriched"	"Detected in many"	6	"glioma: 33.6;liver cancer: 74.6"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"memory CD4 T-cell: 1.5"	"Lineage enriched"	"Detected in single"	15	"T-cells: 1.5"	"Cell line enhanced"	"Detected in many"		"AF22: 48.1;ASC diff: 57.9;ASC TERT1: 22.3;GAMG: 17.2;HAP1: 17.1;NTERA-2: 17.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA036573, HPA057503"	Enhanced		Uncertain	Nucleoplasm,Cytosol		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 47: Cytotrophoblasts - Unknown function"	Nucleoplasm	Cytosol	"HPA036573: AB_10696658, HPA057503: AB_2683451"	"unprognostic (2.34e-2)"	"unprognostic (3.31e-2)"	"unprognostic (1.45e-2)"	"unprognostic (2.11e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.32e-1)"	"prognostic favorable (1.91e-5)"	"unprognostic (1.14e-3)"	"unprognostic (2.63e-1)"	"unprognostic (7.23e-2)"	"unprognostic (9.28e-3)"	"unprognostic (6.69e-2)"	"unprognostic (1.58e-1)"	"unprognostic (2.74e-3)"	"unprognostic (3.06e-2)"	"unprognostic (3.70e-1)"	"unprognostic (2.06e-2)"	119.3	18.1	26.1	3.3	28.2	0.2	35.9	24.6	31.2	9.5	109.8	4.8	0.7	8.3	140.3	3.5	13.7	10.5	26.1	28.3	30.7	3.1	506.7	11.7	6.6	23.6	26.2	25.8	14.2	0.7	20.7	35.2	25.6	9.1	1.8	15.9	7.2	72.8	8.5	3.0	4.0	6.2	25.6	3.7	4.1	15.6	26.7	1.3	9.6	19.9	3.1	8.1	5.7	25.6	0.0	0.0	48.1	0.0	57.9	22.3	0.2	1.4	0.4	4.6	4.5	0.0	0.0	0.0	0.0	0.6	17.2	0.1	17.1	0.0	6.6	0.1	8.5	1.7	0.0	1.4	0.2	0.1	0.0	8.5	0.0	0.7	0.0	1.2	6.3	0.0	0.0	0.0	5.5	0.0	1.2	0.2	17.8	0.0	0.0	0.0	3.2	0.1	0.0	0.0	0.0	11.0	0.1	0.0	0.0	4.0	0.0	5.4	0.0	0.0	4.3	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	26.1	28.2	24.6	31.2	28.3	30.7	23.6	26.2	25.6	25.6	26.7	25.6	4.1	0.0	1.3	6.8	0.7	0.8	0.8	0.0	0.6	27.3	1.0	7.1	3.4	0.0	0.0	1.8	6.2	329.4	0.3	0.0	0.0	9.9	6.0	0.3	7.1	3.1	1.8	2.7	12.2	0.2	17.0	27.8	0.0	0.3	0.0	7.5	33.9	149.5	23.4	1.7	16.4	0.0	0.0	5.7	1.6	15.0	91.0	0.6	1.8	1.0	0.6	31.4	0.0	5.5	3.1	0.3	0.0	37.6	0.0	0.9	0.0	2.0	0.0	3.8	13.1	7.3	3.9	1.6	1.4	0.5	1.3	481.9	0.9	104.7	0.0	0.1
CH25H		ENSG00000138135	"Cholesterol 25-hydroxylase"	O95992	10	89205629-89207317	"Enzymes, Metabolic proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 35.3"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 125.9;Basal squamous epithelial cells: 224.3;Macrophages: 47.3;Microglial cells: 40.3;Smooth muscle cells: 59.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"ASC diff: 8.8;ASC TERT1: 4.4;fHDF/TERT166: 32.8;HSkMC: 8.2"	"Not detected"	"Not detected"			"Region enriched"	"Detected in some"	5	"spinal cord: 6.3"							NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 41: Macrophages - Immune response"				"unprognostic (6.07e-3)"	"unprognostic (2.96e-3)"	"unprognostic (1.57e-1)"	"unprognostic (5.11e-2)"	"unprognostic (2.17e-2)"	"unprognostic (2.02e-1)"	"unprognostic (3.15e-2)"	"unprognostic (2.13e-1)"	"unprognostic (2.54e-1)"	"unprognostic (8.65e-3)"	"unprognostic (7.74e-2)"	"unprognostic (4.76e-2)"	"unprognostic (2.62e-5)"	"unprognostic (2.47e-2)"	"unprognostic (1.40e-1)"	"unprognostic (2.32e-2)"	"unprognostic (2.29e-2)"	21.5	5.1	4.3	7.0	5.0	3.1	7.4	6.5	6.6	3.5	4.4	3.6	3.2	1.3	12.6	14.7	6.0	14.6	4.5	4.2	8.4	7.8	3.6	17.2	4.0	18.4	9.5	2.1	1.6	1.1	9.0	4.2	11.4	4.1	5.5	0.4	2.1	1.3	1.8	3.0	5.6	5.5	8.6	2.0	5.8	0.1	6.0	35.3	2.8	1.0	3.7	18.5	2.1	8.2	0.0	0.0	0.0	0.0	8.8	4.4	0.0	0.1	3.1	0.8	0.9	0.0	0.0	0.0	1.1	32.8	0.9	0.1	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	2.8	0.0	0.0	8.2	0.0	0.4	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.8	4.2	0.0	0.2	0.0	0.1	0.0	0.0	3.5	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.3	5.0	6.5	6.6	4.2	8.4	18.4	9.5	11.4	8.6	6.0	8.2	125.9	3.2	3.4	0.3	1.8	6.9	4.4	11.7	224.3	0.0	6.4	1.0	0.6	0.0	10.0	0.0	0.0	0.1	2.7	0.0	0.0	0.0	0.0	1.5	0.9	23.6	0.0	0.0	2.9	0.0	0.2	33.4	2.0	3.1	1.3	0.0	2.5	0.0	10.2	1.7	0.5	0.0	2.0	12.9	8.2	0.0	0.3	47.3	7.2	40.3	0.0	0.6	0.0	0.0	0.4	0.1	0.0	0.7	4.4	1.0	0.0	0.0	4.5	0.5	6.6	3.6	59.3	0.0	0.0	30.8	6.7	0.1	11.6	0.5	0.0	6.2
CHDH		ENSG00000016391	"Choline dehydrogenase"	Q8NE62	3	53812335-53846419	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"kidney: 37.6;liver: 35.8"	"Cell type enhanced"	"Detected in many"		"Cholangiocytes: 52.9;Hepatocytes: 51.8;Proximal enterocytes: 70.1;Proximal tubular cells: 87.8"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	11	"basophil: 3.1;T-reg: 1.3"	"Group enriched"	"Detected in many"	17	"granulocytes: 3.1;T-cells: 1.3"	"Cell line enhanced"	"Detected in many"		"CACO-2: 11.4;Hep G2: 35.8;OE19: 25.3;T-47d: 11.2"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"HPA036633, HPA058130"	Enhanced					NA	NA			"Cluster 10: Basophils - Unknown function"	"Cluster 22: Non-specific - Unknown function"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA036633: AB_10670841, HPA058130: AB_2683615"	"unprognostic (3.40e-3)"	"unprognostic (1.17e-2)"	"unprognostic (2.26e-3)"	"unprognostic (7.17e-3)"	"unprognostic (9.15e-2)"	"unprognostic (1.17e-3)"	"unprognostic (1.10e-1)"	"unprognostic (1.97e-2)"	"unprognostic (2.75e-1)"	"unprognostic (4.35e-3)"	"unprognostic (4.57e-2)"	"unprognostic (5.12e-2)"	"prognostic favorable (1.88e-8)"	"unprognostic (3.37e-2)"	"unprognostic (2.42e-1)"	"unprognostic (8.26e-2)"	"unprognostic (2.29e-2)"	0.6	2.8	13.6	1.8	14.3	0.6	7.3	12.5	11.4	3.7	16.5	8.9	8.4	2.7	1.4	0.9	2.6	2.7	2.4	11.3	10.9	37.6	35.8	2.4	1.0	14.5	13.9	1.3	16.4	8.3	7.8	0.4	10.1	5.8	9.2	1.5	15.0	1.0	3.9	2.4	14.7	0.9	10.3	0.5	8.0	6.9	15.9	0.2	2.6	1.2	1.2	0.4	0.9	12.0	0.4	4.6	1.2	0.1	0.0	0.0	5.2	0.3	0.5	0.0	0.0	11.4	0.8	0.4	0.8	0.8	0.1	0.0	7.4	0.0	0.0	0.0	4.0	0.0	1.7	35.8	0.0	0.1	0.7	0.1	0.0	0.0	0.0	0.6	0.0	0.0	5.7	0.7	0.0	6.9	0.0	0.1	7.2	25.3	0.8	0.0	1.8	8.2	5.1	4.0	3.0	4.0	1.8	0.1	0.0	0.9	11.2	0.1	0.0	0.0	0.8	0.2	1.0	1.0	1.6	0.0	0.0	0.0	0.0	3.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	1.3	0.0	13.6	14.3	12.5	11.4	11.3	10.9	14.5	13.9	10.1	10.3	15.9	12.0	0.6	3.2	6.8	19.6	1.3	6.6	5.6	1.1	1.2	23.8	23.5	19.8	11.3	52.9	5.9	11.0	14.6	3.7	0.4	16.6	7.9	19.4	28.9	3.2	11.0	1.4	47.9	0.0	2.4	13.8	2.3	2.3	21.4	9.4	7.0	2.2	1.4	51.8	0.3	1.7	3.5	38.9	0.0	1.9	2.5	46.2	5.9	2.6	3.6	1.0	0.1	18.8	0.0	27.2	5.2	8.0	15.1	15.4	5.3	19.8	70.1	87.8	3.8	13.4	0.0	1.0	3.4	15.1	2.3	0.7	5.3	0.8	2.4	2.0	45.4	2.2
COQ7	"CAT5, CLK-1"	ENSG00000167186	"Coenzyme Q7, hydroxylase"	Q99807	16	19067614-19080095	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Ubiquinone biosynthesis"	"Monooxygenase, Oxidoreductase"	"Disease variant, Primary mitochondrial disease"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"basophil: 40.4;neutrophil: 126.5"	"Lineage enriched"	"Detected in all"	8	"granulocytes: 126.5"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA067252, HPA071922"	Approved		Approved	"Nucleoplasm,Plasma membrane"		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 45: Enterocytes - Digestion"	"Plasma membrane"	Nucleoplasm	"HPA067252: AB_2685813, HPA071922: AB_2686473"	"unprognostic (1.37e-1)"	"unprognostic (6.89e-3)"	"unprognostic (1.59e-2)"	"unprognostic (6.08e-2)"	"unprognostic (2.44e-2)"	"unprognostic (9.03e-2)"	"unprognostic (1.31e-1)"	"unprognostic (4.42e-2)"	"unprognostic (1.15e-1)"	"unprognostic (7.27e-3)"	"unprognostic (2.15e-1)"	"unprognostic (8.32e-2)"	"prognostic favorable (8.23e-12)"	"unprognostic (2.19e-1)"	"unprognostic (2.76e-1)"	"unprognostic (3.14e-2)"	"unprognostic (5.27e-2)"	10.2	13.6	10.7	7.0	11.2	4.8	13.4	10.9	11.6	10.8	12.5	14.1	12.4	15.6	12.3	12.4	15.5	10.7	23.4	11.0	10.8	14.1	12.3	10.0	8.3	10.6	11.3	20.0	10.3	24.4	9.7	10.0	11.1	17.7	13.2	14.0	10.4	14.7	45.8	7.9	11.8	11.6	10.4	10.0	12.8	20.9	11.3	10.3	16.2	44.9	8.4	10.3	8.8	13.1	23.5	24.8	21.1	12.4	11.6	12.2	17.7	13.5	11.0	18.0	18.5	15.9	19.1	17.8	63.9	10.4	19.4	24.5	29.6	16.9	13.0	15.2	29.9	9.5	22.8	49.3	14.4	22.9	20.1	10.3	14.6	16.8	12.2	14.8	14.8	20.9	26.4	16.2	12.9	42.4	24.0	18.4	16.1	9.1	13.1	29.0	23.3	22.8	15.7	15.5	30.4	17.4	12.6	27.4	16.2	10.2	25.2	30.7	16.3	19.0	10.9	14.1	19.7	15.0	26.2	19.7	20.4	13.1	12.5	40.4	11.4	17.8	9.9	10.6	9.4	16.3	8.9	8.7	12.6	15.3	12.2	10.8	126.5	12.9	12.3	15.6	6.2	5.6	10.7	11.2	10.9	11.6	11.0	10.8	10.6	11.3	11.1	10.4	11.3	13.1	13.3	16.0	12.6	6.2	35.5	11.0	26.3	20.9	13.6	31.2	18.3	21.1	21.8	31.5	14.9	16.5	39.6	21.2	28.7	38.1	45.0	25.2	14.8	23.7	16.2	16.1	24.0	4.8	6.0	18.0	17.9	14.9	32.1	23.2	25.4	31.1	20.7	11.1	23.3	20.2	8.8	39.0	30.5	29.4	12.9	8.5	18.6	18.8	10.6	4.7	11.6	39.5	8.2	5.0	9.4	13.2	30.4	13.9	11.6	17.8	71.5	23.7	24.4	53.9	19.7	20.0	20.2	81.3	53.1	12.8	12.4	32.2	23.9	38.2	39.8	24.0
CP		ENSG00000047457	Ceruloplasmin	P00450	3	149162410-149221829	"Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters"	"Copper transport, Ion transport, Transport"	Oxidoreductase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	8	"liver: 1871.4"	"Cell type enhanced"	"Detected in many"		"Club cells: 558.1;Glandular and luminal cells: 406.0;Hepatocytes: 1687.2;Muller glia cells: 720.5;Respiratory ciliated cells: 318.4"	"Cancer enhanced"	"Detected in many"		"liver cancer: 98.3"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	10	"EFO-21: 318.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001834, CAB008591"	Supported				"Secreted to blood"	NA	NA	160000000000	440000000000		"Cluster 62: Liver - Hemostasis"	"Cluster 38: EFO-21 - Unknown function"	"Cluster 15: Hepatocytes - Hemostasis"			"CAB008591: AB_1613734, HPA001834: AB_1078502"	"unprognostic (3.58e-1)"	"unprognostic (4.24e-1)"	"unprognostic (9.61e-2)"	"unprognostic (1.80e-2)"	"unprognostic (4.14e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.06e-1)"	"unprognostic (2.97e-2)"	"unprognostic (2.07e-1)"	"unprognostic (8.75e-2)"	"unprognostic (6.03e-2)"	"unprognostic (1.70e-1)"	"prognostic unfavorable (1.14e-7)"	"unprognostic (2.68e-2)"	"unprognostic (1.59e-1)"	"unprognostic (2.00e-1)"	"unprognostic (2.70e-1)"	13.0	2.3	17.9	2.2	18.1	0.9	20.8	18.7	29.8	70.2	129.2	13.0	9.8	14.8	0.0	5.6	8.3	1.1	39.2	17.5	33.0	9.5	1871.4	13.4	18.9	28.1	20.3	0.8	6.5	3.9	28.6	3.4	24.9	7.9	16.4	246.5	39.9	0.9	2.6	13.0	20.8	2.4	19.2	23.1	3.0	1.5	20.1	0.5	16.1	8.3	20.0	23.9	2.3	29.0	0.2	18.8	15.6	0.0	3.3	0.1	0.1	0.0	0.2	0.0	0.0	0.1	0.1	0.1	318.8	0.0	29.4	0.1	0.2	0.0	0.0	0.2	0.2	0.0	0.4	32.7	0.0	0.4	0.0	0.1	0.0	0.0	0.1	0.5	0.0	0.0	0.0	0.2	0.0	0.2	0.0	0.2	2.5	5.4	0.0	0.0	0.0	0.4	6.7	16.2	0.0	0.2	0.3	1.0	0.1	0.4	0.0	0.4	0.0	0.2	1.7	0.2	0.2	0.0	0.0	0.9	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	17.9	18.1	18.7	29.8	17.5	33.0	28.1	20.3	24.9	19.2	20.1	29.0	2.3	19.2	76.6	3.3	10.6	3.3	8.3	28.6	0.6	6.9	14.0	0.6	0.6	65.8	558.1	9.2	6.2	0.1	0.3	0.1	0.0	83.4	0.9	190.5	51.0	12.6	0.0	34.7	1.5	21.4	0.2	16.3	0.0	406.0	2.5	0.1	34.6	1687.2	0.6	5.0	1.4	0.2	8.2	44.6	6.9	1.2	0.3	4.0	0.0	6.5	1.6	720.5	1.0	0.5	2.0	69.3	0.0	0.4	0.3	19.5	0.0	0.3	318.4	24.8	0.0	0.8	15.3	0.0	0.1	0.8	2.6	0.3	4.9	0.1	0.1	79.0
CPOX	"CPO, CPX, HCP"	ENSG00000080819	"Coproporphyrinogen oxidase"	P36551	3	98579446-98593648	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"Heme biosynthesis, Porphyrin biosynthesis"	Oxidoreductase	"Disease variant, Hereditary hemolytic anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Erythroid cells: 352.8;Extravillous trophoblasts: 75.9;Oligodendrocytes: 99.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in all"		"HEL: 166.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015736, HPA054448"			Supported	Mitochondria		No	No		170000	"Cluster 26: Non-specific - Mitochondria"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 36: HEL - Hemostasis"	"Cluster 6: Erythroid cells - Oxygen transport"	Mitochondria		"HPA015736: AB_1847194, HPA054448: AB_2682490"	"unprognostic (2.14e-1)"	"unprognostic (1.04e-1)"	"unprognostic (4.07e-2)"	"unprognostic (6.09e-2)"	"unprognostic (2.71e-1)"	"unprognostic (2.34e-2)"	"unprognostic (8.58e-3)"	"unprognostic (7.14e-2)"	"unprognostic (2.53e-2)"	"unprognostic (2.01e-1)"	"unprognostic (1.10e-2)"	"unprognostic (1.86e-2)"	"prognostic unfavorable (1.04e-5)"	"unprognostic (1.62e-1)"	"unprognostic (2.67e-2)"	"unprognostic (2.15e-2)"	"unprognostic (2.57e-1)"	8.1	10.0	19.7	11.4	28.2	44.1	7.2	24.0	31.7	9.1	13.5	10.0	21.2	10.1	7.2	16.1	7.4	8.1	8.6	19.5	22.4	6.5	35.3	7.5	12.3	30.8	24.9	10.7	7.2	9.5	5.4	18.0	29.8	8.4	12.0	4.5	7.6	7.9	11.2	13.1	15.2	9.0	24.5	9.5	9.4	4.7	25.1	12.8	7.1	9.8	12.3	8.1	10.9	41.8	47.9	22.9	19.9	35.4	36.5	26.9	56.6	30.0	21.7	30.7	34.7	38.2	14.7	5.0	33.1	16.2	33.6	34.1	24.9	32.8	51.9	15.4	21.6	166.4	12.9	49.9	18.5	35.7	37.8	21.2	27.0	29.0	12.0	35.9	29.6	20.2	32.2	20.9	29.1	14.8	36.2	30.4	23.4	26.6	41.0	25.4	45.0	22.1	26.2	19.8	13.1	13.0	32.0	10.9	96.2	22.1	16.7	22.5	24.9	45.1	44.0	26.1	22.4	31.6	26.8	26.7	44.6	38.3	33.7	0.0	0.6	0.0	0.3	0.3	0.7	0.5	0.6	0.8	0.5	0.5	0.2	0.8	0.0	0.6	0.2	0.3	0.3	0.2	19.7	28.2	24.0	31.7	19.5	22.4	30.8	24.9	29.8	24.5	25.1	41.8	6.4	3.2	8.7	9.1	5.6	7.4	3.9	7.3	11.4	4.3	6.0	4.6	8.0	7.2	4.2	3.7	8.4	23.9	6.5	7.9	1.9	3.7	0.1	5.2	8.6	7.4	8.4	352.8	17.7	1.7	75.9	9.4	10.2	5.0	1.3	7.0	11.7	36.4	12.7	0.0	12.3	9.1	4.1	11.3	10.0	0.2	7.5	11.4	12.4	11.2	12.7	5.8	3.1	13.0	99.1	3.2	4.1	7.9	10.4	5.2	9.4	6.3	5.0	5.0	13.1	6.4	7.2	0.3	6.1	12.2	10.2	10.7	12.7	9.7	9.9	4.2
CRYL1	"GDH, lambda-CRY, MGC149525, MGC149526"	ENSG00000165475	"Crystallin lambda 1"	Q9Y2S2	13	20403666-20525873	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"kidney: 329.8;liver: 254.1"	"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 485.2;Hepatocytes: 306.1;Proximal enterocytes: 509.9;Proximal tubular cells: 1033.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"OE19: 68.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA040403, HPA058848"	Approved		Approved	"Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane"		NA	NA		690000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 21: OE19 - Mitochondria"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	"Nucleoplasm, Nucleoli"	"Golgi apparatus, Plasma membrane"	"HPA040403: AB_10795632, HPA058848: "	"unprognostic (1.84e-1)"	"unprognostic (1.25e-1)"	"unprognostic (3.25e-2)"	"prognostic favorable (1.76e-5)"	"unprognostic (3.10e-1)"	"unprognostic (1.03e-1)"	"unprognostic (1.09e-3)"	"unprognostic (4.75e-3)"	"unprognostic (1.19e-1)"	"unprognostic (4.09e-2)"	"unprognostic (2.12e-2)"	"unprognostic (8.80e-2)"	"prognostic favorable (2.30e-9)"	"unprognostic (9.00e-2)"	"unprognostic (1.30e-1)"	"unprognostic (2.39e-2)"	"unprognostic (3.11e-1)"	33.7	31.8	69.5	15.4	81.3	11.2	27.1	75.4	78.1	33.0	65.6	62.1	190.2	30.5	51.7	24.7	26.5	30.0	30.4	65.2	79.0	329.8	254.1	19.9	19.4	76.3	71.9	19.8	46.9	31.4	38.1	16.1	76.1	32.2	49.3	20.7	41.6	36.5	17.0	16.3	131.6	22.8	77.2	23.3	45.2	4.9	71.9	18.0	35.0	20.7	16.3	20.9	23.6	89.8	8.1	6.9	6.4	42.7	31.6	36.1	5.8	11.1	20.0	4.8	3.9	2.6	7.8	0.1	20.6	15.5	10.9	1.9	5.7	9.9	4.9	19.4	4.7	14.2	0.8	55.1	18.1	4.6	12.2	21.5	6.4	3.9	22.0	17.1	51.7	20.3	1.0	5.8	12.7	29.2	12.7	7.2	0.4	68.7	10.2	6.4	3.8	1.0	40.8	16.9	4.2	5.0	6.6	3.1	51.0	3.0	21.2	18.0	50.1	5.8	2.6	14.3	7.1	7.6	1.6	0.0	11.1	7.9	24.5	5.8	50.7	3.2	23.2	59.6	18.9	20.5	30.6	22.1	60.5	23.1	23.5	22.2	1.7	15.6	50.6	6.4	37.5	43.8	69.5	81.3	75.4	78.1	65.2	79.0	76.3	71.9	76.1	77.2	71.9	89.8	29.2	6.4	10.3	57.8	17.7	10.3	15.9	29.7	6.2	6.1	22.0	11.6	10.5	35.8	25.6	77.3	12.5	22.0	10.0	138.5	485.2	26.1	3.6	32.5	8.8	29.1	9.1	6.9	54.5	31.6	11.2	29.8	34.1	27.2	25.3	8.8	50.7	306.1	71.4	1.7	35.3	89.0	32.6	91.6	34.3	4.3	26.1	51.3	37.4	13.1	19.3	112.2	9.2	33.7	114.1	43.2	219.1	24.0	14.3	23.0	509.9	1033.9	20.9	12.6	19.7	23.4	14.7	1.0	2.7	13.0	9.2	20.8	20.1	20.7	105.2	15.0
CRYM	DFNA40	ENSG00000103316	"Crystallin mu"	Q14894	16	21238874-21303083	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Deafness, Disease variant, Non-syndromic deafness"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 78.7;heart muscle: 175.3"	"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 126.0;Ionocytes: 114.0;Muller glia cells: 640.7;Proximal tubular cells: 190.1"	"Cancer enhanced"	"Detected in many"		"prostate cancer: 14.6"	"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in some"	21	"plasmacytoid DC: 82.0"	"Lineage enriched"	"Detected in many"	21	"dendritic cells: 82.0"	"Cell line enriched"	"Detected in some"	4	"RPTEC TERT1: 100.3"	"Group enriched"	"Detected in all"	11	"amygdala: 124.0;basal ganglia: 275.1;cerebral cortex: 124.7;hippocampal formation: 324.3;white matter: 128.4"	"Low region specificity"	"Detected in all"			"HPA019086, HPA030619"	Enhanced		Supported	Cytosol		NA	NA		150000	"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 44: Heart - Cardiac muscle contraction"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 5: Muller glia cells - Visual perception"	Cytosol		"HPA019086: AB_1847260, HPA030619: AB_2673551"	"unprognostic (1.32e-1)"	"unprognostic (2.93e-3)"	"unprognostic (8.96e-2)"	"unprognostic (1.44e-1)"	"unprognostic (2.13e-1)"	"unprognostic (4.62e-2)"	"unprognostic (2.88e-1)"	"unprognostic (5.75e-3)"	"unprognostic (2.81e-1)"	"unprognostic (7.37e-2)"	"unprognostic (2.05e-2)"	"unprognostic (5.95e-2)"	"unprognostic (2.11e-3)"	"unprognostic (7.79e-3)"	"unprognostic (2.49e-2)"	"unprognostic (1.87e-3)"	"unprognostic (1.31e-1)"	1.9	0.8	37.4	0.9	78.7	1.0	2.7	40.6	62.2	3.7	13.6	6.9	1.6	1.0	0.2	7.6	1.1	7.0	175.3	54.0	31.6	64.4	14.2	8.5	1.1	13.9	19.8	0.3	1.8	8.9	55.6	0.4	15.6	35.4	8.4	54.7	20.6	0.2	13.4	4.1	2.6	0.3	14.1	0.3	1.3	5.1	20.5	0.3	0.4	0.9	3.8	21.8	3.6	31.3	0.2	4.0	0.0	0.0	0.2	0.4	0.7	0.0	2.1	0.1	0.2	0.2	0.2	0.3	1.0	0.0	1.8	0.6	5.4	0.0	0.0	0.0	0.8	23.2	0.1	2.3	0.0	0.1	2.2	0.8	0.0	0.8	1.0	0.0	0.0	0.5	0.0	0.4	0.7	0.3	0.0	0.9	9.7	1.6	0.1	0.1	0.0	0.5	100.3	0.1	3.7	5.2	0.2	0.1	2.6	4.8	0.1	0.0	0.0	0.5	0.7	6.8	0.0	0.2	0.0	0.5	16.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.3	2.2	0.0	0.0	0.1	3.9	0.0	0.0	0.3	0.0	0.0	82.0	0.0	1.2	37.4	78.7	40.6	62.2	54.0	31.6	13.9	19.8	15.6	14.1	20.5	31.3	0.3	0.0	20.1	5.2	4.1	2.3	25.4	16.3	0.0	6.3	0.4	11.7	126.0	2.8	56.1	14.7	4.2	0.0	11.4	7.1	17.6	0.1	19.7	3.2	1.5	3.0	13.1	4.8	43.8	0.0	0.0	7.1	6.1	7.7	1.3	1.3	0.4	8.3	0.1	1.7	5.9	20.6	114.0	1.6	0.7	12.4	0.0	1.5	33.8	10.3	0.7	640.7	0.0	7.1	6.6	0.4	2.8	0.0	0.3	19.0	7.5	190.1	19.9	26.2	0.0	0.2	4.3	6.7	7.3	0.2	1.3	0.1	1.1	0.1	8.2	68.0
CRYZ		ENSG00000116791	"Crystallin zeta"	Q08257	1	74705482-74733408	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Oxidoreductase, RNA-binding"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"kidney: 331.0;liver: 282.9"	"Cell type enhanced"	"Detected in many"		"Collecting duct cells: 160.0;Distal tubular cells: 226.9;Hepatocytes: 200.6;Proximal tubular cells: 526.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"RPTEC TERT1: 439.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA021921, HPA023290"	Approved		Supported	Cytosol		NA	NA		6400000	"Cluster 44: Non-specific - Transcription"	"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Cytosol		"HPA021921: AB_1847262, HPA023290: AB_1847263"	"unprognostic (3.64e-2)"	"unprognostic (3.38e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.27e-2)"	"unprognostic (5.32e-3)"	"unprognostic (5.79e-2)"	"unprognostic (6.29e-2)"	"unprognostic (1.04e-1)"	"unprognostic (4.56e-2)"	"unprognostic (1.06e-1)"	"unprognostic (6.38e-3)"	"unprognostic (2.19e-1)"	"unprognostic (1.35e-3)"	"unprognostic (3.12e-1)"	"unprognostic (7.50e-2)"	"unprognostic (2.94e-1)"	"unprognostic (7.32e-2)"	19.8	34.2	19.2	12.9	19.8	2.2	39.0	19.3	36.0	54.6	54.2	21.4	51.2	40.8	120.6	29.0	50.0	68.9	45.6	21.6	23.3	331.0	282.9	32.4	24.4	21.3	24.9	31.6	64.6	52.9	17.0	16.8	24.4	38.8	22.0	15.3	25.0	56.9	25.1	22.2	44.0	40.1	21.1	19.4	25.1	9.2	24.5	33.9	44.5	23.0	23.8	40.8	21.7	24.9	12.1	112.2	57.6	16.3	64.4	70.2	38.6	36.5	57.1	51.8	57.4	88.9	46.1	64.9	62.0	71.3	92.2	31.0	47.2	46.0	83.6	75.2	19.2	27.0	32.2	179.0	33.8	23.1	52.6	33.1	40.0	82.8	15.1	49.1	43.7	35.9	85.9	22.8	109.2	27.0	42.3	38.6	43.1	93.6	72.6	26.8	53.6	23.7	439.4	36.0	15.9	27.9	8.5	60.1	41.2	64.3	54.0	7.7	21.9	12.3	30.7	38.8	55.7	16.2	33.3	32.1	99.4	9.0	35.6	13.1	9.4	1.9	32.1	15.1	26.2	32.8	31.6	30.3	17.1	26.5	27.4	29.5	1.5	30.3	17.9	14.4	42.3	18.8	19.2	19.8	19.3	36.0	21.6	23.3	21.3	24.9	24.4	21.1	24.5	24.9	6.9	28.9	22.6	4.9	20.4	17.8	28.0	32.4	24.5	4.0	16.8	16.8	32.3	84.4	15.7	160.0	2.1	13.5	8.6	6.6	226.9	53.8	0.2	54.8	7.8	8.0	6.7	8.4	4.5	32.4	18.1	20.7	20.9	27.0	14.5	7.8	12.8	200.6	18.5	0.0	4.4	12.0	8.2	15.7	13.7	2.1	20.8	11.4	10.6	4.7	7.1	7.7	11.3	7.1	9.1	31.2	14.5	20.7	20.5	10.2	79.1	526.6	17.3	2.9	0.0	10.6	16.2	1.7	7.4	19.7	21.2	7.3	16.9	13.8	16.2	17.0
CYB5R1	"humb5R2, NQO3A2"	ENSG00000159348	"Cytochrome b5 reductase 1"	Q9UHQ9	1	202961873-202967275	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 605.2"	"Cell type enhanced"	"Detected in all"		"Basal keratinocytes: 187.2;Extravillous trophoblasts: 196.5;Syncytiotrophoblasts: 293.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HaCaT: 187.3;hTCEpi: 188.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA010641, HPA014147"	Enhanced		Approved	Mitochondria,Cytosol		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 38: Extravillous trophoblasts - Unknown function"	Mitochondria	Cytosol	"HPA010641: AB_1078600, HPA014147: AB_1847370"	"unprognostic (6.36e-2)"	"unprognostic (8.51e-2)"	"unprognostic (1.16e-2)"	"prognostic favorable (1.14e-4)"	"unprognostic (1.86e-2)"	"unprognostic (4.34e-2)"	"unprognostic (8.46e-2)"	"unprognostic (1.28e-1)"	"unprognostic (4.03e-1)"	"unprognostic (1.03e-1)"	"unprognostic (5.79e-2)"	"unprognostic (2.89e-1)"	"unprognostic (1.73e-2)"	"unprognostic (2.33e-1)"	"unprognostic (6.14e-2)"	"unprognostic (2.37e-3)"	"unprognostic (1.69e-1)"	38.6	57.3	37.4	23.0	38.8	19.7	43.7	41.1	40.5	49.7	57.3	35.7	19.3	41.2	131.4	61.6	68.2	27.2	154.8	38.3	48.0	64.5	50.2	44.0	25.2	45.4	49.4	41.7	45.1	82.9	46.1	66.6	55.7	41.1	21.2	34.3	56.9	40.0	605.2	123.8	25.7	37.5	39.9	39.1	92.8	50.7	41.4	40.1	40.5	308.0	38.8	52.7	45.8	43.6	34.8	21.3	18.3	37.7	166.0	37.9	178.5	68.3	63.4	43.2	38.4	17.5	39.9	21.5	56.5	68.1	24.0	187.3	14.9	58.0	28.2	31.2	37.8	12.4	24.0	20.4	59.7	10.5	29.6	61.2	188.3	47.5	25.8	36.4	28.9	25.8	37.0	37.6	157.8	40.4	13.6	9.5	12.1	31.0	40.1	21.9	87.6	45.7	41.1	40.8	15.7	19.1	38.0	124.0	57.4	39.4	57.7	23.4	28.5	49.0	20.8	18.7	38.3	34.9	44.5	10.0	53.6	16.2	37.1	24.4	56.7	46.6	27.4	42.6	36.3	23.4	30.9	28.9	37.6	35.0	41.9	29.6	46.0	32.2	29.4	25.9	34.2	52.6	37.4	38.8	41.1	40.5	38.3	48.0	45.4	49.4	55.7	39.9	41.4	43.6	33.0	22.4	29.8	10.1	15.5	187.2	38.5	89.5	42.1	21.0	46.1	41.9	119.3	37.1	60.5	29.5	29.2	171.1	15.8	10.6	7.9	38.3	5.0	58.7	17.3	30.0	19.2	30.7	8.9	48.3	196.5	28.9	31.6	34.9	28.5	13.6	32.9	44.6	63.5	10.1	11.3	10.8	105.8	45.4	29.7	8.6	29.8	39.5	64.0	8.4	20.9	65.9	11.3	11.6	8.1	72.8	11.3	31.2	12.5	25.8	16.0	38.9	75.9	35.0	13.1	49.1	30.0	23.0	4.3	40.6	157.4	293.5	19.5	27.9	14.7	48.2
CYB5R2		ENSG00000166394	"Cytochrome b5 reductase 2"	Q6BCY4	11	7665100-7677222	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"retina: 139.2;testis: 133.6"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 268.0;Late spermatids: 601.1;Spermatocytes: 115.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	7	"eosinophil: 6.1;memory B-cell: 10.6;naive B-cell: 2.8"	"Group enriched"	"Detected in many"	9	"B-cells: 10.6;granulocytes: 6.1"	"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 125.1;BJ hTERT+ SV40 Large T+: 65.9;BJ hTERT+ SV40 Large T+ RasG12V: 59.4;HBF TERT88: 52.0;NTERA-2: 69.8;WM-115: 96.3"	"Low region specificity"	"Detected in single"							"HPA038962, HPA061707"	Enhanced		Approved	"Nucleoplasm,Golgi apparatus"		NA	NA			"Cluster 19: B-cells - Humoral immune response"	"Cluster 77: Retina - Visual perception"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 25: Spermatids - Spermatogenesis"	"Golgi apparatus"	Nucleoplasm	"HPA038962: AB_10675954, HPA061707: AB_2732668"	"unprognostic (1.47e-1)"	"unprognostic (2.56e-2)"	"unprognostic (8.90e-3)"	"unprognostic (4.41e-2)"	"unprognostic (4.13e-3)"	"unprognostic (1.60e-2)"	"unprognostic (4.02e-2)"	"unprognostic (2.48e-1)"	"unprognostic (3.41e-2)"	"unprognostic (1.30e-2)"	"unprognostic (2.64e-3)"	"unprognostic (1.10e-1)"	"unprognostic (4.78e-2)"	"unprognostic (1.40e-1)"	"unprognostic (8.16e-2)"	"unprognostic (1.70e-1)"	"unprognostic (7.01e-2)"	8.8	3.6	17.2	5.7	23.1	4.1	15.6	18.7	25.3	15.6	13.2	4.6	2.4	22.8	25.5	19.6	10.1	6.8	4.7	18.2	19.7	5.9	5.1	11.5	2.7	19.5	22.5	29.3	4.3	29.0	1.3	13.8	19.2	19.5	5.3	139.2	35.7	22.3	1.7	51.1	4.3	13.2	16.9	3.0	5.6	133.6	21.8	0.9	5.1	1.7	10.5	13.3	17.7	28.0	7.1	3.6	1.5	0.0	0.3	1.7	22.8	43.9	125.1	65.9	59.4	0.7	9.4	0.2	10.3	22.7	20.2	0.8	0.1	0.3	52.0	0.1	0.2	0.0	3.8	0.9	35.0	0.4	6.6	17.7	1.4	0.3	3.7	0.1	5.6	0.0	6.9	0.1	0.5	0.0	0.0	0.1	69.8	7.4	3.4	34.1	0.1	0.0	0.0	4.4	0.0	0.7	0.3	28.0	1.9	11.1	4.8	9.4	0.0	6.1	0.1	0.3	3.4	0.2	0.0	10.7	0.5	0.0	96.3	0.0	0.9	6.1	0.0	0.5	0.0	10.6	0.1	0.0	0.0	2.8	0.0	0.0	0.1	0.0	0.4	0.0	0.0	0.6	17.2	23.1	18.7	25.3	18.2	19.7	19.5	22.5	19.2	16.9	21.8	28.0	0.6	22.4	5.1	0.0	2.3	7.0	8.4	12.3	8.6	1.3	8.8	12.8	3.0	1.5	6.3	3.7	20.9	5.3	0.1	0.6	0.0	1.4	268.0	5.5	11.2	1.7	0.0	0.0	0.0	4.7	20.0	8.1	1.5	14.3	2.5	0.5	0.4	1.8	2.5	0.0	0.1	1.8	6.1	0.0	0.5	601.1	4.7	1.5	5.4	1.9	0.5	0.8	0.0	0.5	8.5	6.0	1.4	6.0	2.9	11.2	0.3	0.4	10.2	35.2	13.1	2.3	7.5	115.6	9.8	12.8	10.1	4.5	0.2	1.8	1.8	11.4
CYB5R3	DIA1	ENSG00000100243	"Cytochrome b5 reductase 3"	P00387	22	42617840-42649392	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Oxidoreductase	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"ASC diff: 830.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001566	Approved		Supported	"Endoplasmic reticulum"		NA	NA		1500000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 48: Smooth muscle cells - ECM organization"	"Endoplasmic reticulum"		"HPA001566: AB_1078601"	"unprognostic (4.73e-2)"	"unprognostic (2.93e-1)"	"unprognostic (1.79e-1)"	"unprognostic (1.89e-1)"	"unprognostic (3.05e-1)"	"unprognostic (1.04e-2)"	"prognostic unfavorable (2.13e-5)"	"unprognostic (2.45e-1)"	"unprognostic (8.22e-3)"	"unprognostic (3.01e-1)"	"unprognostic (2.72e-2)"	"unprognostic (6.76e-2)"	"unprognostic (3.33e-3)"	"unprognostic (1.31e-1)"	"unprognostic (1.64e-1)"	"unprognostic (1.92e-1)"	"unprognostic (5.24e-2)"	404.4	310.5	147.1	87.4	152.9	82.7	272.2	145.7	189.9	237.3	115.0	192.4	94.8	248.4	58.8	152.4	174.0	139.5	374.3	138.7	163.9	182.9	279.4	201.3	76.3	194.7	174.2	218.3	89.1	62.0	137.4	107.8	169.9	181.4	74.9	27.3	149.8	239.3	203.0	233.6	138.1	200.2	154.8	101.4	182.0	142.7	156.7	54.0	157.8	140.5	72.3	216.7	210.0	160.2	125.5	78.6	126.6	78.6	830.9	654.7	74.4	359.2	330.0	262.2	232.4	104.0	95.6	58.8	156.6	668.8	113.8	112.4	85.3	178.0	133.7	63.9	187.3	83.6	127.3	202.4	211.0	118.4	149.5	397.4	138.1	188.9	124.5	190.8	220.0	74.0	73.5	296.3	361.9	137.9	116.8	108.4	51.0	129.2	142.7	84.9	153.8	131.3	202.0	90.6	56.1	73.2	118.6	113.2	134.0	92.6	90.6	112.0	340.9	282.0	175.3	192.3	137.9	78.3	91.2	72.4	328.8	67.8	237.9	126.3	104.0	300.3	75.9	135.3	76.6	110.1	72.8	83.9	154.0	102.7	50.8	54.0	53.8	63.5	176.7	140.8	95.0	86.4	147.1	152.9	145.7	189.9	138.7	163.9	194.7	174.2	169.9	154.8	156.7	160.2	238.5	86.6	62.2	17.0	51.7	110.1	95.5	184.8	27.3	16.7	52.3	73.2	106.4	105.8	100.9	60.7	4.2	110.0	37.0	90.5	49.0	216.4	4.8	51.4	82.9	161.5	83.7	113.9	12.3	107.0	199.3	183.4	38.2	65.4	62.8	57.8	180.2	230.4	108.3	16.8	16.1	45.8	142.4	50.6	112.0	17.0	253.9	67.7	176.1	25.3	112.5	91.0	33.0	7.1	26.4	156.8	85.6	280.6	36.7	82.3	116.9	110.8	53.3	18.4	190.7	62.5	202.5	23.8	45.5	57.5	112.7	117.9	43.0	233.1	55.2	96.4
CYB5R4	"b5+b5R, dJ676J13.1, NCB5OR"	ENSG00000065615	"Cytochrome b5 reductase 4"	Q7L1T6	6	83859656-83967423	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 179.2;Late spermatids: 364.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 199.1"	"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HDLM-2: 75.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA018992	Approved					NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 25: Spermatids - Spermatogenesis"			"HPA018992: AB_1847371"	"unprognostic (4.86e-3)"	"unprognostic (1.16e-1)"	"unprognostic (1.80e-3)"	"unprognostic (1.21e-2)"	"unprognostic (1.72e-1)"	"unprognostic (3.25e-2)"	"unprognostic (1.72e-2)"	"unprognostic (7.94e-2)"	"unprognostic (4.77e-1)"	"unprognostic (6.77e-2)"	"unprognostic (1.39e-2)"	"unprognostic (5.44e-1)"	"unprognostic (6.36e-2)"	"unprognostic (1.95e-1)"	"unprognostic (4.11e-2)"	"unprognostic (2.15e-1)"	"unprognostic (8.15e-2)"	5.1	3.1	4.0	12.0	4.4	17.0	3.6	9.8	6.0	2.4	1.0	7.1	6.5	3.0	3.2	4.5	2.3	3.2	4.2	3.7	4.0	4.0	3.9	5.1	9.8	4.0	2.9	2.5	5.6	2.6	1.9	3.4	4.7	3.0	5.0	5.4	3.6	2.5	6.3	3.1	7.3	3.5	2.6	8.8	7.0	12.1	4.1	6.6	2.3	4.4	7.1	5.3	3.1	8.2	10.6	9.2	6.5	8.1	3.4	4.6	12.0	7.0	10.9	10.4	14.8	12.7	6.8	19.9	10.8	4.7	27.7	8.8	6.1	10.1	7.5	75.1	14.2	47.0	5.2	7.0	6.4	28.5	40.0	6.1	2.8	7.3	7.1	4.2	5.8	17.2	17.1	14.1	7.7	4.5	7.4	9.6	3.6	8.5	8.9	12.3	23.3	6.9	5.6	10.9	17.4	9.6	8.7	8.2	9.5	3.9	5.0	16.3	7.2	10.2	8.5	21.2	22.4	16.4	27.0	10.7	11.8	19.2	11.7	104.0	59.0	177.3	16.6	50.4	13.6	27.4	14.6	15.0	46.6	26.9	9.4	14.7	199.1	14.2	58.1	19.7	23.9	29.3	4.0	4.4	9.8	6.0	3.7	4.0	4.0	2.9	4.7	2.6	4.1	8.2	9.9	6.4	13.9	31.3	46.5	11.1	14.4	17.5	8.0	15.5	8.5	5.8	15.4	11.5	18.3	7.3	16.7	5.9	31.3	22.0	11.7	25.7	179.2	8.4	9.2	9.7	16.2	10.1	46.6	25.1	20.5	9.2	21.9	13.5	25.3	6.0	4.2	11.3	45.1	13.5	51.0	14.8	28.5	56.6	49.7	364.5	8.4	59.4	16.0	37.5	74.4	5.8	47.4	48.7	85.8	28.4	17.3	7.5	27.1	13.6	15.7	21.6	14.8	18.7	6.6	16.9	13.1	25.7	27.3	12.5	14.8	11.5	28.2	8.3	13.3	23.6
CYB5RL	LOC606495	ENSG00000215883	"Cytochrome b5 reductase like"	Q6IPT4	1	54169651-54200036	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA042671, HPA060463"	Approved		Enhanced	Nucleoplasm		NA	NA			"Cluster 40: NK-cells - Unknown function"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"	Nucleoplasm		"HPA042671: AB_2678107, HPA060463: AB_2684286"	"unprognostic (2.03e-1)"	"unprognostic (1.36e-1)"	"unprognostic (1.72e-2)"	"unprognostic (1.84e-2)"	"unprognostic (2.15e-1)"	"unprognostic (1.13e-3)"	"unprognostic (1.90e-4)"	"unprognostic (6.45e-3)"	"unprognostic (9.75e-2)"	"unprognostic (2.04e-1)"	"unprognostic (5.93e-2)"	"unprognostic (2.58e-1)"	"unprognostic (2.35e-1)"	"unprognostic (1.80e-2)"	"unprognostic (5.08e-2)"	"unprognostic (5.74e-2)"	"unprognostic (2.86e-1)"	2.1	4.4	1.6	1.4	1.8	2.3	2.5	1.7	2.0	2.4	2.7	2.5	2.7	2.7	2.5	2.3	2.8	2.2	3.4	1.7	1.2	2.5	2.9	1.8	2.6	1.4	1.4	4.4	4.2	2.9	3.7	1.6	1.4	2.4	2.8	2.7	3.7	1.7	4.1	3.8	2.1	2.5	1.2	3.1	3.1	1.4	1.5	1.7	3.1	4.1	2.6	2.0	1.9	1.8	3.6	4.7	6.3	6.6	5.0	4.8	2.2	2.8	4.0	5.3	5.7	4.4	3.9	6.0	3.2	1.9	12.1	3.3	10.1	2.9	6.0	6.8	4.1	6.8	8.0	4.7	3.8	5.8	3.4	2.6	3.8	6.3	2.8	3.7	4.7	5.3	7.5	2.8	3.9	4.3	5.9	3.2	6.4	4.1	3.7	9.3	7.8	5.6	2.4	4.0	9.3	4.6	1.9	6.3	5.7	5.1	4.4	4.4	2.1	4.0	3.3	6.0	5.0	4.3	7.1	8.5	4.5	12.2	6.3	0.7	0.4	0.4	0.2	0.9	0.1	0.2	0.3	0.1	0.4	0.3	0.2	0.2	0.5	0.8	0.2	0.4	0.1	0.3	1.6	1.8	1.7	2.0	1.7	1.2	1.4	1.4	1.4	1.2	1.5	1.8	1.6	0.0	7.2	1.3	1.3	0.1	1.1	0.9	0.0	4.0	2.3	2.4	5.1	2.8	3.0	3.7	4.2	1.9	0.4	1.1	7.9	3.0	0.1	3.6	2.0	6.1	2.4	6.1	2.4	4.2	2.3	2.4	1.1	2.1	2.5	4.8	3.9	2.9	5.3	0.0	2.2	1.2	4.1	1.6	0.4	1.0	1.5	1.2	0.0	2.8	1.2	1.9	4.1	2.5	3.1	1.4	0.8	1.9	2.0	0.8	1.4	2.7	5.9	4.0	0.0	2.6	1.4	1.2	5.1	0.8	0.9	0.3	1.6	2.9	2.3	0.9
CYP11A1	"CYP11A, P450SCC"	ENSG00000140459	"Cytochrome P450 family 11 subfamily A member 1"	P05108	15	74337759-74367646	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Steroidogenesis, Sterol metabolism"	"Monooxygenase, Oxidoreductase"	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	26	"adrenal gland: 1009.9"	"Cell type enhanced"	"Detected in some"		"Extravillous trophoblasts: 345.1;Peritubular cells: 173.8;Syncytiotrophoblasts: 1452.0;Theca cells: 637.4"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in single"	48	"basophil: 10.2"	"Lineage enriched"	"Detected in single"	48	"granulocytes: 10.2"	"Group enriched"	"Detected in some"	5	"BEWO: 55.2;HEL: 46.8"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"basal ganglia: 1.8;hippocampal formation: 1.1;hypothalamus: 1.3;midbrain: 4.5;pons: 1.1"	HPA016436	Enhanced					NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"			"HPA016436: AB_1847423"	"unprognostic (8.89e-2)"	"unprognostic (6.96e-2)"	"unprognostic (4.95e-3)"	"unprognostic (9.31e-2)"	"unprognostic (9.42e-4)"	"unprognostic (1.90e-1)"	"unprognostic (1.55e-3)"	"unprognostic (8.06e-2)"	"unprognostic (3.04e-1)"	"unprognostic (2.95e-1)"	"unprognostic (1.77e-2)"	"unprognostic (5.45e-2)"	"unprognostic (9.66e-4)"	"unprognostic (2.40e-2)"	"unprognostic (2.74e-1)"	"unprognostic (3.04e-2)"	"unprognostic (7.95e-2)"	2.0	1009.9	2.0	0.6	2.1	0.1	1.9	2.3	2.0	2.0	3.5	0.8	0.3	1.6	0.8	6.3	2.4	0.4	1.4	2.0	2.1	0.6	3.6	0.6	0.1	2.8	2.5	38.9	0.3	0.0	2.8	25.2	2.8	1.2	0.2	0.7	1.2	0.5	2.5	0.6	0.8	0.9	2.6	4.9	0.9	23.0	1.9	0.3	0.3	1.0	2.1	0.5	1.0	1.9	0.0	0.0	0.0	0.2	0.0	0.4	55.2	0.1	0.0	0.4	0.1	0.0	0.0	0.0	1.3	0.1	0.2	0.0	0.0	0.0	0.3	0.0	0.2	46.8	1.2	0.5	0.2	0.0	0.2	1.9	0.0	0.0	0.0	0.1	0.0	0.0	1.0	0.0	0.0	0.1	0.0	0.1	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.3	11.1	0.0	0.0	8.2	0.0	0.0	0.0	0.0	0.5	0.2	0.0	0.1	0.0	0.0	0.1	0.1	0.0	10.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	2.0	2.1	2.3	2.0	2.0	2.1	2.8	2.5	2.8	2.6	1.9	1.9	0.1	0.0	0.0	6.2	0.0	0.3	0.0	0.0	34.1	0.1	0.6	0.9	1.2	2.8	0.0	0.0	0.0	144.6	0.0	0.0	1.9	0.0	1.6	0.2	4.9	0.8	0.0	0.0	0.2	0.0	345.1	10.0	0.0	0.2	0.0	41.3	0.0	3.6	22.0	0.0	0.2	0.0	0.0	0.0	0.0	6.7	48.7	0.4	0.0	1.0	0.6	6.2	0.0	0.0	0.2	0.5	0.0	173.8	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.8	1.2	4.6	2.8	8.7	0.0	1452.0	0.0	637.4	0.0	0.0
CYP11B1	"CPN1, CYP11B, FHI, P450C11"	ENSG00000160882	"Cytochrome P450 family 11 subfamily B member 1"	P15538	8	142872356-142879846	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroidogenesis"	"Monooxygenase, Oxidoreductase"	"Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	877	"adrenal gland: 3686.5"	"Group enriched"	"Detected in some"	113	"Early spermatids: 53.3;Late spermatids: 83.4"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"											"HPA049171, HPA049565, HPA056348, HPA057752"	Supported		Approved	Mitochondria		NA	NA				"Cluster 17: Adrenal gland - Steroid metabolism"		"Cluster 25: Spermatids - Spermatogenesis"	Mitochondria		"HPA049171: AB_2680661, HPA049565: , HPA056348: AB_2683104, HPA057752: AB_2683516"																		0.2	3686.5	0.1	0.9	0.6	0.0	0.1	0.0	0.1	0.2	0.5	0.2	0.0	0.2	0.0	0.4	0.2	0.0	0.4	0.3	0.0	0.9	0.5	0.3	0.0	0.1	0.1	0.3	0.5	0.0	0.4	0.0	0.0	0.3	0.0	0.0	1.4	0.0	0.2	0.2	0.2	0.0	0.0	0.3	0.4	4.2	0.0	0.0	0.2	0.0	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.6	0.0	0.1	0.3	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	53.3	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	83.4	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0
CYP11B2	"ALDOS, CPN2, CYP11B, CYP11BL, P-450C18, P450aldo"	ENSG00000179142	"Cytochrome P450 family 11 subfamily B member 2"	P19099	8	142910559-142917843	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Lipid metabolism, Steroid metabolism, Steroidogenesis"	"Monooxygenase, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	603	"adrenal gland: 179.0"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"											"HPA049171, HPA049565, HPA056348, HPA057752"	Supported		Uncertain	Mitochondria		NA	NA				"Cluster 17: Adrenal gland - Steroid metabolism"		"Cluster 43: Cardiomyocytes - Nuclear processes"	Mitochondria		"HPA049171: AB_2680661, HPA049565: , HPA056348: AB_2683104, HPA057752: AB_2683516"																		0.0	179.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
CYP17A1	"CPT7, CYP17, P450C17, S17AH"	ENSG00000148795	"Cytochrome P450 family 17 subfamily A member 1"	P05093	10	102830531-102837472	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	Steroidogenesis	"Lyase, Monooxygenase, Oxidoreductase"	"Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	84	"adrenal gland: 8229.5"	"Cell type enriched"	"Detected in some"	17	"Theca cells: 1871.0"	"Cancer enriched"	"Detected in many"	5	"liver cancer: 22.7"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HMC-1: 3.0;SCLC-21H: 1.5"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA048533	Enhanced		Approved	Vesicles	"Intracellular and membrane"	NA	NA				"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 52: Non-specific - Transcription"	Vesicles		"HPA048533: AB_2680432"	"unprognostic (1.07e-2)"	"unprognostic (8.84e-2)"	"unprognostic (3.01e-2)"	"unprognostic (9.08e-2)"	"unprognostic (1.91e-1)"	"unprognostic (6.29e-2)"	"unprognostic (2.92e-3)"	"unprognostic (2.39e-4)"	"unprognostic (8.26e-2)"	"unprognostic (2.35e-1)"	"unprognostic (5.92e-3)"	"unprognostic (1.13e-1)"	"prognostic favorable (5.43e-7)"	"unprognostic (1.07e-1)"	"unprognostic (5.56e-2)"	"unprognostic (1.66e-2)"	"unprognostic (2.94e-4)"	0.4	8229.5	0.0	2.1	0.0	0.0	0.4	0.1	0.1	1.1	0.0	0.5	0.0	0.8	0.1	0.9	1.0	0.4	1.0	0.0	0.0	52.9	6.7	1.4	0.0	0.0	0.1	16.6	1.7	10.5	0.7	0.0	0.0	0.7	0.0	0.2	3.4	0.0	1.0	0.7	0.6	0.0	0.0	0.9	1.3	98.3	0.0	0.0	2.9	0.0	0.0	0.8	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	2.2	0.1	0.4	0.1	0.0	0.5	0.0	0.1	0.7	0.0	0.0	1.8	0.0	0.4	0.1	0.1	21.5	0.0	41.6	0.1	0.0	0.7	0.0	2.7	0.1	0.2	0.0	1.3	0.0	0.1	0.0	0.1	0.4	6.1	0.1	1.7	0.1	0.0	0.0	0.6	0.7	10.6	1.8	0.9	0.0	0.0	0.1	0.2	3.1	0.5	0.1	0.7	0.0	0.0	0.0	0.3	0.0	104.3	0.0	1.2	0.0	1.2	0.6	0.3	0.1	0.0	0.0	0.3	0.4	1871.0	0.0	0.1
CYP19A1	"ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM"	ENSG00000137869	"Cytochrome P450 family 19 subfamily A member 1"	P11511	15	51208057-51338601	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Monooxygenase, Oxidoreductase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	14	"placenta: 124.4"	"Cell type enriched"	"Detected in some"	10	"Syncytiotrophoblasts: 2007.5"	"Cancer enhanced"	"Detected in single"		"glioma: 0.6"	"Group enriched"	"Detected in many"	4	"amygdala: 4.8;hypothalamus: 4.1;medulla oblongata: 1.4;midbrain: 2.0;thalamus: 3.7"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"ASC TERT1: 92.8;HDLM-2: 17.5;HSkMC: 31.4;SuSa: 16.3"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB000355, HPA051194"	Enhanced		Uncertain	Mitochondria		NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 28: Placenta - Pregnancy"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"	Mitochondria		"CAB000355: , HPA051194: AB_2681381"	"unprognostic (9.41e-2)"	"unprognostic (7.44e-2)"	"unprognostic (9.52e-5)"	"unprognostic (6.81e-2)"	"unprognostic (2.72e-1)"	"unprognostic (4.25e-4)"	"unprognostic (5.18e-5)"	"unprognostic (1.54e-3)"	"unprognostic (2.38e-2)"	"unprognostic (2.52e-1)"	"unprognostic (1.97e-1)"	"unprognostic (5.37e-2)"	"unprognostic (1.54e-5)"	"unprognostic (2.52e-3)"	"unprognostic (2.11e-1)"	"unprognostic (1.40e-2)"	"unprognostic (1.11e-1)"	8.3	9.0	4.8	0.4	0.6	0.2	2.1	0.1	0.5	0.6	0.0	0.2	0.7	0.3	0.0	0.1	0.3	0.5	1.2	0.3	4.1	0.1	0.1	0.7	0.0	1.4	2.0	3.2	1.3	0.2	0.0	124.4	0.7	0.6	0.1	0.6	0.9	2.7	0.6	1.8	0.2	1.3	0.2	0.6	0.2	6.5	3.7	0.2	2.4	0.3	0.0	3.5	0.5	0.7	0.1	0.0	0.0	0.0	1.7	92.8	6.0	0.1	0.3	0.0	0.1	0.2	0.0	0.0	0.3	0.5	0.4	0.0	0.0	0.0	0.0	17.5	0.0	0.6	0.2	8.1	0.6	0.0	0.1	31.4	0.0	0.3	4.0	0.3	0.0	0.0	0.0	0.8	0.4	0.7	0.0	0.1	0.1	0.8	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2	2.4	0.2	16.3	0.0	0.5	0.1	0.3	0.1	0.2	0.0	3.0	1.6	0.0	0.8	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	4.8	0.6	0.1	0.5	0.3	4.1	1.4	2.0	0.7	0.2	3.7	0.7	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	52.8	0.0	0.0	0.0	0.0	2.8	0.0	0.0	0.7	0.0	0.0	0.1	0.0	7.9	1.5	0.0	0.0	0.0	191.3	0.0	0.0	14.0	0.0	0.3	0.0	0.0	0.9	0.0	5.1	0.6	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.1	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	6.6	0.2	0.9	12.3	0.3	0.0	0.0	2007.5	0.0	22.2	0.0	0.0
CYP1A1	"CP11, CYP1, P1-450, P450-C, P450DX"	ENSG00000140465	"Cytochrome P450 family 1 subfamily A member 1"	P04798	15	74719542-74725536	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	"Lyase, Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 66.1;urinary bladder: 63.6"	"Cell type enhanced"	"Detected in some"		"Adipocytes: 21.9;Endothelial cells: 13.7;Glandular and luminal cells: 5.9;Hepatocytes: 9.9;Urothelial cells: 16.4"	"Group enriched"	"Detected in some"	24	"liver cancer: 18.6;urothelial cancer: 54.9"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"CACO-2: 36.9;hTCEpi: 19.5;HUVEC TERT2: 19.1;SK-BR-3: 14.7;SuSa: 35.6"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			CAB018654	Uncertain					NA	NA				"Cluster 85: Liver - Metabolism"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 22: Epithelial cell types - Mixed function"			"CAB018654: AB_2088699"	"unprognostic (1.71e-2)"	"unprognostic (7.86e-2)"	"unprognostic (2.57e-2)"	"unprognostic (2.89e-1)"	"unprognostic (5.45e-3)"	"unprognostic (6.34e-2)"	"unprognostic (3.08e-1)"	"unprognostic (6.24e-3)"	"unprognostic (1.11e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.41e-1)"	"unprognostic (1.03e-1)"	"unprognostic (4.21e-2)"	"unprognostic (6.70e-2)"	"unprognostic (2.20e-1)"	"unprognostic (4.77e-1)"	"unprognostic (1.28e-1)"	18.5	0.6	0.2	0.0	0.2	0.0	14.7	0.1	0.3	3.6	0.0	2.0	0.6	2.4	0.6	1.9	1.2	0.7	10.7	0.2	0.4	1.4	66.1	12.2	0.0	0.3	0.4	0.5	0.6	0.0	0.5	0.3	0.3	0.7	0.1	0.3	1.8	0.6	4.1	13.9	19.8	0.0	0.1	0.1	1.8	0.3	0.2	0.2	2.0	0.2	0.1	63.6	2.2	0.1	0.3	2.1	0.2	0.0	0.5	0.1	11.7	0.0	0.1	0.7	0.3	36.9	1.6	0.3	9.6	0.0	8.8	11.4	0.7	7.3	0.3	0.0	1.0	0.5	2.6	5.5	0.2	0.3	11.5	0.0	19.5	0.3	1.4	0.4	19.1	0.3	2.3	0.3	0.1	0.7	0.1	0.4	0.2	12.1	2.9	1.2	0.0	0.4	0.0	2.4	0.6	0.3	1.7	14.7	3.8	35.6	0.4	0.2	1.0	1.6	0.5	5.2	0.0	0.7	0.2	0.5	0.0	0.3	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.2	0.1	0.3	0.2	0.4	0.3	0.4	0.3	0.1	0.2	0.1	21.9	0.0	0.0	0.0	0.1	0.5	2.4	0.0	0.0	0.0	0.4	0.5	0.6	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	3.4	1.1	13.7	0.0	0.0	0.1	0.2	0.0	0.2	0.0	5.9	0.0	0.0	0.0	9.9	0.0	0.0	0.4	0.0	0.0	0.0	0.7	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	3.6	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.1	0.1	0.0	0.4	0.0	0.1	0.0	0.0	16.4
CYP1A2	"CP12, P3-450"	ENSG00000140505	"Cytochrome P450 family 1 subfamily A member 2"	P05177	15	74748845-74756607	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins"	"Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism"	"Lyase, Monooxygenase, Oxidoreductase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	313	"liver: 513.4"	"Cell type enriched"	"Detected in some"	57	"Hepatocytes: 85.7"	"Group enriched"	"Detected in some"	22	"liver cancer: 25.3;urothelial cancer: 6.5"	"Low region specificity"	"Detected in some"			"Immune cell enhanced"	"Detected in some"		"neutrophil: 2.1"	"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in some"		"SK-BR-3: 2.3"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			CAB016531	Enhanced					NA	NA			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 60: Liver - Hemostasis & Lipid metabolism"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 2: Hepatocytes - Metabolism"			"CAB016531: AB_629359"				"unprognostic (1.54e-4)"			"unprognostic (1.29e-1)"	"unprognostic (1.98e-1)"	"unprognostic (1.74e-1)"	"unprognostic (1.59e-2)"		"unprognostic (1.76e-1)"	"unprognostic (1.17e-2)"	"unprognostic (5.48e-2)"	"unprognostic (2.33e-2)"	"unprognostic (7.41e-2)"	"unprognostic (2.53e-1)"	0.2	0.3	0.5	0.2	0.5	1.0	0.1	1.6	0.8	0.0	0.2	0.0	0.2	0.2	0.4	0.1	0.2	0.2	0.1	0.5	0.5	0.2	513.4	0.4	0.3	0.6	0.5	0.1	0.0	0.0	0.0	0.7	0.6	0.1	0.1	0.4	0.2	0.3	0.3	0.6	0.2	0.0	0.1	0.3	0.2	0.3	0.6	0.1	1.4	0.0	0.1	0.1	0.0	1.3	0.4	0.3	0.8	0.5	0.1	0.0	0.6	0.2	0.0	0.0	0.1	0.3	0.4	0.8	0.1	0.0	0.6	0.4	0.0	0.0	0.0	0.1	0.4	0.9	0.6	0.1	0.0	0.7	0.3	0.1	0.1	0.0	0.0	0.3	0.1	1.3	0.7	1.3	0.0	0.2	0.9	0.3	0.4	0.3	0.2	0.9	0.8	0.3	0.1	0.7	0.7	0.3	0.6	2.3	0.1	0.6	0.5	0.2	0.2	0.3	0.4	0.3	0.3	0.3	0.2	0.5	0.3	0.9	0.3	1.5	0.3	0.5	0.2	0.2	0.1	0.3	0.2	0.1	0.1	0.5	0.2	0.2	2.1	0.4	0.2	0.4	0.1	0.1	0.5	0.5	1.6	0.8	0.5	0.5	0.6	0.5	0.6	0.1	0.6	1.3	0.0	0.0	0.0	0.0	0.4	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.3	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	85.7	0.1	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2
CYP1B1	"CP1B, GLC3A"	ENSG00000138061	"Cytochrome P450 family 1 subfamily B member 1"	Q16678	2	38066973-38109902	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Fatty acid metabolism, Lipid metabolism, Steroid metabolism"	"Lyase, Monooxygenase, Oxidoreductase"	"Disease variant, Glaucoma, Peters anomaly"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Peritubular cells: 170.8;Prostatic glandular cells: 747.6;Urothelial cells: 498.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in many"	7	"classical monocyte: 156.9"	"Lineage enriched"	"Detected in many"	24	"monocytes: 156.9"	"Cell line enhanced"	"Detected in many"		"ASC diff: 128.7;ASC TERT1: 136.8;HSkMC: 551.3;hTERT-RPE1: 128.9;SiHa: 270.0;U-87 MG: 142.2"	"Low region specificity"	"Detected in many"			"Region enhanced"	"Detected in all"		"spinal cord: 34.6"	"CAB011705, HPA026863"	Approved		Uncertain	Mitochondria		NA	NA			"Cluster 25: Monocytes - Inflammatory response"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 22: Epithelial cell types - Mixed function"	Mitochondria		"CAB011705: AB_731810, HPA026863: AB_10600900"	"unprognostic (7.25e-3)"	"unprognostic (2.28e-1)"	"unprognostic (1.24e-3)"	"unprognostic (2.27e-1)"	"unprognostic (2.04e-2)"	"unprognostic (1.68e-1)"	"unprognostic (5.45e-2)"	"unprognostic (1.80e-1)"	"unprognostic (3.38e-1)"	"unprognostic (9.69e-2)"	"unprognostic (4.20e-1)"	"unprognostic (1.84e-1)"	"prognostic unfavorable (4.39e-6)"	"unprognostic (1.87e-3)"	"unprognostic (1.81e-1)"	"unprognostic (6.67e-2)"	"prognostic unfavorable (2.76e-4)"	28.4	12.0	2.7	31.9	6.2	2.0	29.4	1.6	8.9	34.9	10.4	3.7	2.2	41.0	19.5	7.6	44.9	23.8	29.2	2.5	2.3	24.1	7.0	16.8	11.6	3.6	2.9	5.6	7.2	0.9	14.8	4.5	3.0	34.7	2.1	1.2	4.3	39.2	3.4	6.3	5.8	35.1	3.6	27.3	15.9	8.0	7.3	28.3	8.7	5.5	1.9	35.0	6.7	1.5	7.0	71.9	2.3	0.0	128.7	136.8	0.4	0.6	4.4	1.3	12.3	0.2	30.1	0.0	19.1	17.8	3.1	58.7	0.3	4.0	2.3	5.5	3.8	0.0	21.2	0.0	36.0	0.2	0.1	551.3	55.3	30.7	1.4	128.9	0.0	0.3	0.7	0.2	0.7	29.2	0.3	22.5	7.5	10.4	14.2	0.1	0.0	0.2	13.4	0.9	0.5	2.1	270.0	38.8	0.0	7.5	49.4	10.8	0.0	1.1	0.2	107.9	0.1	0.3	0.2	0.0	142.2	0.1	11.8	1.6	156.9	0.0	0.1	23.2	0.0	0.1	0.1	0.0	1.5	0.0	0.1	0.1	6.5	0.1	18.6	0.7	0.1	70.2	2.7	6.2	1.6	8.9	2.5	2.3	3.6	2.9	3.0	3.6	7.3	1.5	56.8	19.2	66.3	0.0	1.7	17.7	118.4	86.9	8.0	0.7	18.3	42.0	3.4	0.0	79.7	46.0	0.0	0.3	1.1	0.9	15.6	6.0	15.1	11.7	100.4	103.8	1.8	0.0	4.5	0.5	0.8	114.1	3.6	28.2	3.8	0.1	7.5	12.2	12.6	0.0	0.3	1.3	4.1	103.0	50.6	12.1	159.7	112.2	17.8	64.6	140.1	1.6	3.1	0.0	0.2	0.6	0.1	170.8	0.3	747.6	0.1	1.6	11.2	0.5	19.7	4.5	32.7	12.6	2.6	2.4	14.2	0.3	2.4	1.3	1.0	498.7
CYP21A2	"CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B"	ENSG00000231852	"Cytochrome P450 family 21 subfamily A member 2"	P08686	6	32038327-32041644	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	Steroidogenesis	"Monooxygenase, Oxidoreductase"	"Congenital adrenal hyperplasia, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	46	"adrenal gland: 2041.7"	"Cell type enriched"	"Detected in some"	6	"Hepatocytes: 15.9"	"Cancer enhanced"	"Detected in some"		"liver cancer: 2.7"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"HDLM-2: 3.3"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA048979, HPA053371"	Enhanced					NA	NA				"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 15: Hepatocytes - Hemostasis"			"HPA048979: AB_2680584, HPA053371: AB_2682131"	"unprognostic (1.03e-2)"	"unprognostic (1.65e-1)"	"unprognostic (1.02e-4)"	"unprognostic (2.58e-1)"	"unprognostic (2.97e-1)"	"unprognostic (2.93e-2)"	"unprognostic (2.76e-2)"	"unprognostic (8.75e-2)"	"unprognostic (1.39e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.41e-1)"	"unprognostic (1.93e-1)"	"unprognostic (6.67e-7)"	"unprognostic (7.39e-2)"	"unprognostic (5.24e-2)"	"unprognostic (1.09e-1)"	"unprognostic (1.82e-1)"	2.0	2041.7	0.0	0.0	0.0	0.0	1.5	0.0	0.6	1.9	0.0	2.5	0.0	1.5	0.6	0.6	2.4	0.0	2.9	0.0	0.0	7.0	44.8	0.8	0.0	0.0	0.0	4.3	0.9	0.0	1.9	0.0	0.0	1.9	0.0	0.0	4.0	0.0	0.3	0.7	1.1	0.0	0.0	5.5	0.8	0.8	0.0	0.0	2.3	0.0	0.0	2.1	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.3	0.1	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.1	0.2	0.0	0.4	2.4	0.5	0.3	1.5	0.8	0.0	0.0	0.0	0.4	0.0	0.0	0.2	0.1	0.1	0.8	0.9	1.8	0.0	0.1	0.0	0.0	1.6	0.0	0.2	1.3	0.4	0.0	15.9	0.0	0.0	0.1	0.0	0.0	0.3	0.3	0.1	0.6	0.1	1.8	0.0	0.0	0.3	0.0	0.0	0.1	0.3	0.0	0.0	0.0	0.2	0.0	2.0	1.2	0.6	0.0	0.3	0.6	0.6	0.4	0.0	0.0	0.0	0.3	1.0	0.0	0.0
CYP24A1	"CP24, CYP24, P450-CC24"	ENSG00000019186	"Cytochrome P450 family 24 subfamily A member 1"	Q07973	20	54153446-54173986	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		"Monooxygenase, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"endometrium 1: 14.9;kidney: 35.3;lymphoid tissue: 10.5;placenta: 10.0;urinary bladder: 28.7"	"Cell type enhanced"	"Detected in some"		"Basal prostatic cells: 48.3;Basal respiratory cells: 142.7;Basal squamous epithelial cells: 74.0;Club cells: 47.0;Proximal tubular cells: 61.3;Urothelial cells: 36.7"	"Cancer enhanced"	"Detected in many"		"lung cancer: 18.3;urothelial cancer: 21.0"	"Low region specificity"	"Detected in some"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	17	"A549: 411.5;Hep G2: 122.6"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"HPA022261, HPA063771"	Enhanced		Approved	"Nucleoplasm,Plasma membrane,Mitochondria"		NA	Yes			"Cluster 39: Non-specific - mRNA processing"	"Cluster 7: Kidney - Transmembrane transport"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"	"Nucleoplasm, Mitochondria"	"Plasma membrane"	"HPA022261: AB_1847427, HPA063771: AB_2685120"	"unprognostic (1.19e-7)"	"unprognostic (1.73e-1)"	"unprognostic (2.24e-2)"	"unprognostic (7.69e-3)"	"unprognostic (3.30e-1)"	"unprognostic (2.30e-2)"		"unprognostic (1.11e-2)"	"unprognostic (2.12e-1)"	"unprognostic (2.09e-2)"	"unprognostic (5.37e-3)"	"unprognostic (1.23e-1)"	"unprognostic (6.05e-2)"	"unprognostic (5.98e-2)"	"unprognostic (1.36e-1)"	"unprognostic (4.38e-2)"	"unprognostic (2.12e-1)"	0.0	0.0	0.2	0.4	0.4	0.0	3.7	0.0	0.3	1.7	0.0	0.0	0.1	14.9	0.2	3.8	0.2	0.0	0.0	0.1	1.8	35.3	0.4	0.7	0.2	0.4	2.0	0.0	0.0	0.0	0.2	10.0	0.3	2.9	0.0	0.0	0.3	2.0	0.0	0.9	0.0	0.2	0.1	0.0	0.0	0.0	0.6	0.2	1.3	0.0	10.5	28.7	1.3	0.2	0.5	411.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.7	12.6	0.0	3.2	0.0	0.9	15.8	0.0	0.1	0.1	0.0	0.0	0.0	6.5	122.6	0.0	0.0	0.0	0.1	0.0	0.0	0.9	0.2	0.0	0.0	0.0	0.0	0.0	11.1	0.0	0.0	0.0	0.0	0.4	0.0	0.0	1.7	0.0	7.0	1.3	0.0	2.6	0.6	0.0	0.1	0.1	0.0	0.0	0.0	16.0	0.0	0.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.4	0.0	0.3	0.1	1.8	0.4	2.0	0.3	0.1	0.6	0.2	0.0	0.0	0.0	0.0	1.3	22.8	48.3	142.7	74.0	0.0	11.0	8.6	0.4	0.0	47.0	0.0	0.0	0.1	0.1	0.1	5.9	0.1	0.0	0.7	0.5	0.3	0.0	0.0	0.2	0.0	0.1	2.0	0.0	4.5	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	12.2	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.2	0.0	0.0	0.0	9.8	0.0	61.3	13.1	0.0	0.0	0.0	0.6	0.0	0.0	3.3	19.6	0.1	0.1	0.0	0.2	36.7
CYP27A1	"CP27, CTX, CYP27"	ENSG00000135929	"Cytochrome P450 family 27 subfamily A member 1"	Q02318	2	218781749-218815293	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism"	"Monooxygenase, Oxidoreductase"	"Cataract, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	7	"liver: 594.4"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 404.3;Hofbauer cells: 148.9;Proximal enterocytes: 206.3"	"Group enriched"	"Detected in all"	4	"liver cancer: 176.9;melanoma: 85.7"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	8	"classical monocyte: 151.5;neutrophil: 126.3"	"Group enriched"	"Detected in many"	21	"granulocytes: 126.3;monocytes: 151.5"	"Cell line enhanced"	"Detected in many"		"Hep G2: 299.6;HSkMC: 54.7;RPTEC TERT1: 78.5;SK-MEL-30: 103.6;WM-115: 42.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA059155	Enhanced		Approved	Mitochondria,Cytosol		NA	NA			"Cluster 25: Monocytes - Inflammatory response"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 2: Hepatocytes - Metabolism"	Mitochondria	Cytosol	"HPA059155: AB_2683933"	"prognostic favorable (1.05e-4)"	"unprognostic (4.21e-2)"	"unprognostic (2.34e-1)"	"unprognostic (1.83e-3)"	"unprognostic (3.71e-3)"	"unprognostic (1.31e-2)"	"prognostic favorable (8.62e-6)"	"unprognostic (6.04e-2)"	"unprognostic (1.73e-1)"	"unprognostic (4.04e-1)"	"unprognostic (1.25e-3)"	"unprognostic (8.76e-3)"	"unprognostic (1.09e-3)"	"unprognostic (1.08e-1)"	"unprognostic (7.51e-2)"	"unprognostic (1.64e-1)"	"unprognostic (1.36e-1)"	23.1	50.3	45.2	15.7	59.0	1.3	21.8	57.0	59.3	27.6	75.6	27.6	77.8	19.8	11.6	11.9	34.0	19.1	30.7	42.2	49.3	46.4	594.4	71.7	24.6	63.0	56.1	32.6	8.3	18.5	29.6	6.2	62.7	41.8	20.7	22.5	40.4	29.5	37.9	17.5	81.9	13.2	50.6	13.0	13.8	12.6	58.8	23.6	12.6	49.2	28.0	24.3	23.2	69.2	0.2	0.0	2.7	0.2	4.6	3.3	0.4	1.9	11.7	3.9	7.8	13.7	0.8	0.0	4.3	7.6	0.2	0.1	0.0	0.0	1.7	1.4	1.0	0.0	0.4	299.6	16.2	0.4	0.3	54.7	0.5	0.1	0.0	12.8	5.9	0.0	0.3	0.1	8.3	0.0	0.0	0.2	2.3	0.3	0.5	0.1	2.4	0.5	78.5	0.2	0.2	0.2	0.1	0.0	103.6	2.4	1.6	2.2	5.9	0.0	0.2	0.1	6.0	0.0	0.0	0.1	0.1	0.3	42.9	0.0	151.5	0.4	0.2	17.1	0.3	0.7	0.2	0.5	6.5	0.0	0.1	0.0	126.3	0.0	1.2	0.8	0.0	44.1	45.2	59.0	57.0	59.3	42.2	49.3	63.0	56.1	62.7	50.6	58.8	69.2	10.6	3.2	28.9	33.6	0.9	5.2	52.4	8.5	21.6	15.3	12.7	18.8	5.1	17.2	11.3	3.7	27.1	0.7	0.5	37.0	9.8	12.1	1.0	12.6	4.3	10.3	24.5	8.4	2.2	12.0	0.7	35.4	2.6	14.8	2.5	1.9	19.6	404.3	148.9	10.1	3.9	20.0	4.1	18.2	5.1	1.0	47.5	104.3	49.8	15.0	92.4	28.7	0.0	26.7	108.5	9.7	44.0	26.7	0.0	43.3	206.3	76.9	21.4	14.1	0.0	12.8	7.2	0.7	0.1	3.2	3.1	1.2	2.3	1.2	30.3	20.4
CYP27B1	"CYP1, P450c1, PDDR, VDD1"	ENSG00000111012	"Cytochrome P450 family 27 subfamily B member 1"	O15528	12	57762334-57768986	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		"Monooxygenase, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"kidney: 15.2;thyroid gland: 5.7"	"Group enriched"	"Detected in many"	5	"Exocrine glandular cells: 22.1;monocytes: 22.8;Proximal tubular cells: 36.9"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Immune cell enriched"	"Detected in single"	6	"MAIT T-cell: 1.2"	"Lineage enriched"	"Detected in single"	12	"T-cells: 1.2"	"Cell line enhanced"	"Detected in many"		"hTERT-HME1: 13.6;RH-30: 22.6"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"									NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 7: Kidney - Transmembrane transport"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"				"unprognostic (8.59e-2)"	"unprognostic (1.42e-1)"	"unprognostic (8.89e-2)"	"unprognostic (2.77e-2)"	"unprognostic (4.16e-2)"	"unprognostic (1.03e-2)"	"unprognostic (1.28e-2)"	"unprognostic (1.44e-1)"	"unprognostic (2.10e-2)"	"unprognostic (4.72e-2)"	"unprognostic (2.51e-1)"	"unprognostic (1.17e-2)"	"unprognostic (1.75e-3)"	"unprognostic (4.10e-2)"	"unprognostic (3.19e-2)"	"prognostic unfavorable (6.79e-4)"	"unprognostic (5.67e-3)"	0.3	0.9	0.3	0.7	0.3	0.8	0.8	0.3	0.4	0.2	0.3	0.4	0.4	0.2	0.6	0.4	0.2	0.5	0.1	0.3	0.3	15.2	0.6	0.5	0.9	0.3	0.3	0.2	1.6	1.0	0.4	0.3	0.3	0.3	0.6	3.3	0.5	0.2	0.1	0.6	0.5	0.1	0.3	0.2	0.5	0.4	0.3	0.2	5.7	0.0	0.7	2.2	0.2	0.5	2.8	0.4	0.0	0.3	0.2	0.4	1.1	0.1	3.1	1.0	0.3	3.7	1.0	2.0	0.1	0.4	0.3	3.3	0.5	5.9	3.1	0.6	0.4	0.9	0.0	1.0	0.3	1.2	2.5	0.5	1.9	0.8	13.6	1.2	0.4	2.6	1.3	1.2	0.4	0.4	0.4	1.1	1.3	2.8	2.3	0.8	22.6	1.7	0.5	0.3	0.7	0.8	2.0	0.4	0.1	0.1	1.7	2.3	0.2	0.2	1.6	1.1	0.4	1.4	1.2	0.4	1.2	2.6	1.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.1	0.2	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.3	0.3	0.4	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.5	0.5	0.0	0.0	0.7	3.0	5.2	1.3	1.1	0.6	0.7	5.1	2.7	0.7	2.8	1.9	0.0	2.1	0.1	0.0	0.6	1.9	2.0	0.9	1.1	0.5	0.5	0.0	0.0	0.3	22.1	0.4	0.6	0.0	1.7	4.5	0.4	0.4	0.3	2.3	0.0	0.2	0.6	0.0	0.3	0.8	0.0	0.0	1.5	0.0	0.0	22.8	0.6	0.0	0.0	0.1	5.4	0.1	0.4	1.7	1.4	0.5	36.9	0.6	5.2	0.0	1.5	1.1	0.3	0.7	1.3	2.7	0.1	0.5	0.4	0.9	0.6
CYP27C1	FLJ16008	ENSG00000186684	"Cytochrome P450 family 27 subfamily C member 1"	Q4G0S4	2	127183832-127220313	"Enzymes, Predicted intracellular proteins"		"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"cervix: 4.1;skin 1: 5.1"	"Cell type enhanced"	"Detected in some"		"Club cells: 5.4;Collecting duct cells: 3.7;Endometrial stromal cells: 5.8;Leydig cells: 7.5;Pancreatic endocrine cells: 7.6;Suprabasal keratinocytes: 7.2"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in some"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"HaCaT: 7.6;HDLM-2: 11.8;hTERT-RPE1: 12.5;TIME: 11.6;U-138 MG: 10.9;U-251 MG: 7.9"									"HPA062460, HPA068731"			Enhanced	Vesicles		NA	NA			"Cluster 11: Basophils - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 11: RPE1 & U-87MG - Synaptic function"	"Cluster 36: Stromal cells - Cell proliferation"	Vesicles		"HPA062460: AB_2732683, HPA068731: AB_2686023"	"unprognostic (1.90e-1)"	"unprognostic (4.07e-2)"	"unprognostic (1.15e-1)"	"unprognostic (1.38e-2)"	"unprognostic (3.03e-1)"	"unprognostic (7.75e-3)"	"unprognostic (3.48e-1)"	"unprognostic (2.31e-3)"	"unprognostic (4.38e-2)"	"unprognostic (3.15e-1)"	"unprognostic (1.81e-3)"	"unprognostic (1.11e-1)"	"unprognostic (6.29e-4)"	"unprognostic (3.49e-4)"	"unprognostic (1.83e-1)"	"unprognostic (4.27e-2)"	"unprognostic (8.64e-2)"	0.6	0.5	0.8	0.4	0.2	0.3	0.3	0.8	0.7	4.1	0.6	1.2	0.3	0.6	0.4	1.6	0.6	0.7	0.9	0.5	1.0	0.2	0.2	0.2	0.3	0.6	2.4	0.2	0.2	0.0	0.1	0.1	0.4	0.9	0.3	0.1	0.3	0.7	0.4	5.1	0.6	0.2	0.3	0.2	0.3	0.3	2.7	0.0	0.1	0.1	0.8	1.8	2.5	0.8	1.3	3.4	1.9	0.1	0.1	0.0	0.1	0.4	3.2	1.8	0.8	0.1	2.8	0.1	0.1	2.0	1.3	7.6	2.7	1.4	0.6	11.8	1.4	0.0	2.0	0.1	0.0	0.0	0.0	0.1	0.0	0.4	1.1	12.5	0.4	0.3	0.0	0.2	2.1	0.2	0.3	0.1	4.0	0.0	1.0	0.1	0.2	0.0	5.9	1.0	0.1	0.7	4.9	0.0	0.0	1.5	0.1	0.2	11.6	10.9	2.0	5.3	7.9	0.1	0.1	0.0	0.1	0.1	0.9	0.5	0.1	0.0	0.2	0.1	0.1	0.1	0.1	0.1	0.0	0.2	0.1	0.2	0.4	0.2	0.1	0.1	0.1	0.0	0.8	0.2	0.8	0.7	0.5	1.0	0.6	2.4	0.4	0.3	2.7	0.8	0.2	0.0	0.6	0.0	0.2	1.8	1.2	2.1	0.0	0.0	1.5	0.3	0.5	0.0	5.4	3.7	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.4	5.8	0.5	0.0	0.0	0.6	0.2	0.0	2.4	0.0	0.5	0.0	0.2	0.4	0.1	0.0	0.0	0.7	0.0	2.0	0.0	1.9	0.1	7.5	0.2	0.0	0.0	0.1	0.0	0.0	0.5	0.2	7.6	0.0	0.4	0.0	1.6	0.0	0.0	0.2	0.0	0.0	1.5	1.0	0.1	0.7	0.0	7.2	0.0	0.2	0.0	0.0	2.9
CYP2A13	"CPAD, CYP2A"	ENSG00000197838	"Cytochrome P450 family 2 subfamily A member 13"	Q16696	19	41088451-41096195	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	8	"liver: 2.0"	"Group enriched"	"Detected in some"	8	"Club cells: 2.0;Early spermatids: 4.2;Late spermatids: 3.7"	"Cancer enriched"	"Detected in single"	5	"liver cancer: 2.3"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"											"HPA046713, HPA047262"	Supported				"Intracellular and membrane"	NA	NA				"Cluster 62: Liver - Hemostasis"		"Cluster 34: Spermatids - Unknown function"			"HPA046713: AB_2679767, HPA047262: AB_2680005"	"unprognostic (9.79e-2)"						"unprognostic (1.00e-1)"	"unprognostic (4.51e-3)"		"unprognostic (4.92e-2)"				"unprognostic (1.99e-1)"	"unprognostic (1.49e-1)"			0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.2	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.3	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.1
CYP2A7	CYP2A	ENSG00000198077	"Cytochrome P450 family 2 subfamily A member 7"	P20853	19	40875439-40882752	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	71	"liver: 152.5"	"Cell type enriched"	"Detected in some"	8	"Hepatocytes: 195.3"	"Group enriched"	"Detected in some"	238	"breast cancer: 9.2;liver cancer: 25.6"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"											"CAB033510, HPA046713, HPA047262"	Enhanced				"Intracellular and membrane"	NA	NA				"Cluster 62: Liver - Hemostasis"		"Cluster 15: Hepatocytes - Hemostasis"			"CAB033510: AB_782366, HPA046713: AB_2679767, HPA047262: AB_2680005"	"unprognostic (2.18e-1)"				"unprognostic (3.60e-2)"		"unprognostic (2.65e-3)"	"unprognostic (8.89e-2)"		"unprognostic (1.39e-2)"	"unprognostic (3.95e-1)"	"unprognostic (9.21e-2)"	"unprognostic (8.71e-2)"	"unprognostic (3.99e-2)"		"unprognostic (1.06e-2)"		0.0	0.0	0.2	0.0	0.2	0.0	0.5	0.0	0.6	2.1	0.0	0.0	0.1	0.3	0.0	0.0	0.1	0.0	0.0	0.2	0.0	0.0	152.5	0.1	0.0	0.1	0.0	0.3	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.2	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.2	0.0	0.6	0.2	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.1	4.3	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	24.0	0.1	0.2	0.0	0.2	0.0	0.0	0.0	0.2	11.0	195.3	0.0	0.0	0.1	0.8	0.0	14.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.2	0.0	0.9
CYP2C18	"CPCI, CYP2C, CYP2C17, P450IIC17"	ENSG00000108242	"Cytochrome P450 family 2 subfamily C member 18"	P33260	10	94683729-94736190	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"intestine: 102.8;liver: 197.0;stomach 1: 67.2"	"Cell type enhanced"	"Detected in some"		"Gastric mucus-secreting cells: 68.8;Hepatocytes: 124.0;Proximal enterocytes: 62.5;Squamous epithelial cells: 22.8"	"Cancer enhanced"	"Detected in many"		"liver cancer: 18.9"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"BEWO: 3.2;OE19: 1.9"	"Not detected"	"Not detected"							HPA074424			Uncertain	"Vesicles,Plasma membrane"	"Intracellular and membrane"	NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 2: Hepatocytes - Metabolism"	Vesicles	"Plasma membrane"	"HPA074424: "	"unprognostic (2.40e-1)"	"unprognostic (1.75e-2)"	"unprognostic (2.69e-1)"	"unprognostic (1.10e-2)"		"unprognostic (1.32e-2)"	"unprognostic (2.57e-1)"	"unprognostic (2.71e-1)"	"unprognostic (9.78e-2)"	"unprognostic (2.28e-1)"	"unprognostic (4.22e-3)"		"unprognostic (1.62e-3)"	"unprognostic (1.29e-1)"	"unprognostic (1.08e-1)"		"unprognostic (6.81e-3)"	0.3	0.0	0.0	1.6	0.1	0.0	0.3	0.2	0.1	5.3	0.0	5.9	102.8	0.1	0.0	30.9	0.0	16.3	0.0	0.1	0.0	0.3	197.0	0.8	0.0	0.2	0.0	0.0	0.3	0.0	0.0	0.1	0.1	0.0	2.5	0.0	5.4	0.0	0.0	4.4	83.1	0.1	0.1	0.0	67.2	0.1	0.1	0.3	0.0	0.0	7.1	0.2	9.5	0.2	0.0	0.1	0.0	0.1	0.0	0.0	3.2	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	1.9	0.0	0.0	0.0	0.4	0.2	0.1	0.1	0.2	0.1	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.1	0.1	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.1	0.1	0.0	0.2	0.0	0.1	0.1	0.1	0.2	0.0	0.0	3.3	0.0	0.3	0.1	0.0	1.6	0.0	0.0	0.0	0.1	0.1	17.2	3.2	0.0	0.0	0.1	0.0	6.7	0.0	1.5	0.0	0.6	0.1	0.0	0.0	2.7	0.5	6.9	0.2	0.1	68.8	1.3	0.0	0.0	1.8	124.0	0.0	0.0	0.8	2.1	2.0	2.9	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	9.1	3.9	0.0	0.3	0.0	62.5	0.0	0.9	0.0	0.0	0.0	0.1	0.1	0.3	22.8	1.7	1.5	0.1	0.1	5.7	0.0
CYP2C19	"CPCJ, CYP2C, P450IIC19"	ENSG00000165841	"Cytochrome P450 family 2 subfamily C member 19"	P33261	10	94762681-94855547	"Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Monooxygenase, Oxidoreductase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	6	"liver: 190.2"	"Group enriched"	"Detected in some"	11	"Gastric mucus-secreting cells: 3.1;Hepatocytes: 9.5;Proximal enterocytes: 8.6"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"											"HPA015066, HPA074424"	Supported		Uncertain	Vesicles	"Intracellular and membrane"	NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 85: Liver - Metabolism"		"Cluster 2: Hepatocytes - Metabolism"	Vesicles		"HPA015066: AB_1847433, HPA074424: "			"unprognostic (3.15e-2)"			"unprognostic (2.13e-1)"	"unprognostic (2.48e-1)"				"unprognostic (1.83e-2)"			"unprognostic (1.53e-1)"				0.0	0.0	0.1	0.0	0.1	0.2	0.0	0.3	0.2	0.2	0.1	0.2	32.4	0.0	0.1	1.6	0.0	1.7	0.0	0.1	0.0	0.0	190.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.2	0.0	0.0	0.6	13.9	0.0	0.0	0.0	3.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.4	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.1	0.1	0.1	0.1	0.0	0.1	0.0	0.0	0.0	0.1	0.1	0.1	0.4	0.2	0.1	0.1	0.0	0.0	0.1	0.1	0.3	0.2	0.1	0.0	0.1	0.0	0.1	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.2	0.0	0.0	3.1	0.0	0.0	0.0	0.4	9.5	0.0	0.0	0.6	0.1	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.1	0.0	0.0	0.0	0.0	8.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.3	0.0
CYP2C8	CPC8	ENSG00000138115	"Cytochrome P450 family 2 subfamily C member 8"	P10632	10	95036772-95069497	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Lipid metabolism, Steroid metabolism"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	359	"liver: 2156.6"	"Cell type enriched"	"Detected in some"	12	"Hepatocytes: 1834.2"	"Cancer enriched"	"Detected in some"	82	"liver cancer: 102.3"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"											"HPA013547, HPA013970, HPA015066, HPA074424"	Enhanced		Uncertain	"Vesicles,Plasma membrane"	"Intracellular and membrane"	NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 62: Liver - Hemostasis"		"Cluster 2: Hepatocytes - Metabolism"	Vesicles	"Plasma membrane"	"HPA013547: AB_1847435, HPA013970: AB_1847434, HPA015066: AB_1847433, HPA074424: "	"unprognostic (3.33e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.55e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.09e-2)"	"unprognostic (1.80e-3)"	"unprognostic (4.29e-2)"	"unprognostic (1.03e-1)"	"unprognostic (3.38e-1)"	"prognostic favorable (9.82e-4)"	"unprognostic (2.85e-1)"	"unprognostic (1.44e-3)"	"unprognostic (2.63e-1)"	"unprognostic (7.88e-2)"	"unprognostic (1.39e-1)"	"unprognostic (4.05e-4)"	0.3	1.8	1.7	0.0	1.9	0.2	0.3	1.4	2.1	0.3	1.4	0.4	0.2	0.1	0.3	0.1	1.1	4.6	0.3	1.8	2.2	1.4	2156.6	0.4	0.1	1.7	2.2	0.1	1.7	0.5	3.1	0.1	1.8	0.6	0.0	3.1	0.2	0.3	0.2	0.1	1.1	0.0	1.4	1.0	6.0	4.0	2.1	0.2	0.9	0.0	0.1	0.2	0.2	1.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.2	0.2	0.0	0.2	0.1	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.7	0.5	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.7	1.9	1.4	2.1	1.8	2.2	1.7	2.2	1.8	1.4	2.1	1.8	0.0	0.0	0.0	1.6	8.9	0.0	0.1	0.0	0.0	1.1	0.1	0.0	0.2	147.3	0.1	0.0	0.0	0.1	0.0	0.2	0.0	0.0	7.3	0.9	0.1	2.0	1.8	57.5	4.5	0.2	0.0	0.1	0.0	0.2	0.0	0.6	52.8	1834.2	0.0	5.0	3.7	0.1	0.0	70.9	0.0	7.4	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.5	1.2	0.5	1.2	0.0	0.0	0.1	1.0	0.8	0.9	1.7	0.0	0.0	0.3	2.1	0.6	0.0	0.0	0.0	3.3	0.0	0.2	0.2
CYP2C9	"CYP2C10, P450IIC9"	ENSG00000138109	"Cytochrome P450 family 2 subfamily C member 9"	P11712	10	94938658-94990091	"Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Lipid metabolism, Steroid metabolism, Sterol metabolism"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	20	"liver: 1719.9"	"Cell type enriched"	"Detected in some"	26	"Hepatocytes: 1704.9"	"Cancer enriched"	"Detected in some"	41	"liver cancer: 118.4"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"											"HPA015066, CAB016123, HPA074424"	Enhanced		Uncertain	"Vesicles,Plasma membrane"	"Intracellular and membrane"	NA	NA				"Cluster 60: Liver - Hemostasis & Lipid metabolism"		"Cluster 2: Hepatocytes - Metabolism"	Vesicles	"Plasma membrane"	"CAB016123: AB_629363, HPA015066: AB_1847433, HPA074424: "	"unprognostic (3.37e-1)"	"unprognostic (5.68e-2)"	"unprognostic (9.67e-2)"	"unprognostic (4.16e-2)"		"unprognostic (1.83e-2)"	"prognostic favorable (2.83e-6)"	"unprognostic (2.37e-1)"	"unprognostic (2.05e-2)"		"unprognostic (4.93e-2)"		"unprognostic (1.26e-4)"	"unprognostic (7.55e-2)"	"unprognostic (1.12e-1)"	"unprognostic (2.45e-2)"	"unprognostic (1.24e-2)"	0.2	0.0	0.0	0.4	0.0	0.2	0.1	0.1	0.0	1.2	0.0	2.7	87.8	0.0	0.0	7.7	0.0	7.9	0.0	0.0	0.0	4.3	1719.9	0.2	0.1	0.1	0.0	0.0	0.4	0.0	0.0	0.0	0.1	0.0	0.3	0.0	1.0	0.0	0.0	2.3	46.2	0.1	0.0	0.5	18.4	0.0	0.0	0.0	0.0	0.0	0.2	0.1	2.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.2	0.0	0.0	0.0	0.3	0.0	0.1	0.0	0.0	0.1	0.4	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	2.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	18.6	0.2	1.8	0.0	0.0	0.0	1.5	0.0	7.6	0.0	0.8	0.7	1.1	0.0	16.0	0.0	0.7	0.0	0.2	44.4	7.4	0.0	0.0	26.7	1704.9	0.0	0.0	0.1	1.4	0.0	34.6	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	1.0	2.6	0.0	0.1	0.0	65.3	1.8	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.5	0.0	0.1	1.9	0.0	2.7	0.0
CYP2E1	CYP2E	ENSG00000130649	"Cytochrome P450 family 2 subfamily E member 1"	P05181	10	133520406-133561220	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Monooxygenase, Oxidoreductase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	309	"liver: 10379.8"	"Cell type enriched"	"Detected in many"	58	"Hepatocytes: 6272.7"	"Cancer enriched"	"Detected in some"	278	"liver cancer: 265.3"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"MAIT T-cell: 2.5;myeloid DC: 6.2"	"Group enriched"	"Detected in many"	16	"dendritic cells: 6.2;T-cells: 2.5"	"Cell line enhanced"	"Detected in many"		"HaCaT: 11.0;HL-60: 8.9;HMC-1: 8.9;NB-4: 24.0"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"HPA009128, HPA029564"	Enhanced		Approved	"Endoplasmic reticulum,Mitochondria"	"Intracellular and membrane"	NA	NA			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 62: Liver - Hemostasis"	"Cluster 24: NB-4 - Immune response"	"Cluster 2: Hepatocytes - Metabolism"	"Endoplasmic reticulum, Mitochondria"		"HPA009128: AB_1078613, HPA029564: AB_10602213"	"unprognostic (6.32e-2)"	"unprognostic (1.51e-2)"	"unprognostic (3.83e-5)"	"unprognostic (1.27e-1)"	"unprognostic (3.37e-2)"	"unprognostic (1.26e-1)"	"unprognostic (2.92e-3)"	"unprognostic (6.36e-3)"	"unprognostic (2.41e-2)"	"unprognostic (1.49e-1)"	"unprognostic (1.63e-1)"	"unprognostic (3.21e-2)"	"unprognostic (1.70e-4)"	"unprognostic (1.72e-1)"	"unprognostic (8.36e-2)"	"unprognostic (3.78e-1)"	"unprognostic (9.59e-2)"	2.8	2.9	5.4	0.6	5.4	0.8	3.0	9.1	7.5	4.9	3.0	5.0	1.4	4.5	8.3	16.7	5.5	2.5	2.1	5.5	5.5	9.1	10379.8	2.6	2.0	6.1	5.5	4.1	12.4	0.6	4.1	1.4	6.7	5.3	1.2	11.5	3.6	6.1	2.8	13.8	2.2	2.2	5.0	7.2	6.7	3.7	6.3	1.7	4.0	0.9	33.6	3.5	3.2	7.5	0.1	0.0	0.3	1.0	3.5	1.9	0.7	1.6	4.5	0.0	0.3	0.0	2.7	1.4	0.2	0.5	0.0	11.0	0.0	0.2	0.4	0.3	1.5	1.8	0.2	1.3	0.6	8.9	8.9	1.0	0.2	0.0	0.7	1.9	0.0	3.1	0.6	0.4	1.0	0.7	0.6	24.0	6.4	4.3	0.4	0.4	6.1	0.0	2.0	0.0	0.0	0.0	4.2	0.0	0.6	0.2	0.3	0.9	0.0	1.4	0.4	2.3	1.0	2.2	1.0	3.0	1.5	7.4	0.1	0.0	0.0	0.0	0.0	0.0	2.5	0.0	1.1	0.6	6.2	0.0	0.1	0.0	0.0	0.1	0.2	0.0	0.0	0.2	5.4	5.4	9.1	7.5	5.5	5.5	6.1	5.5	6.7	5.0	6.3	7.5	0.8	0.0	1.1	5.5	9.2	2.3	0.2	0.7	0.6	5.7	0.6	0.5	2.8	48.6	1.9	0.0	2.1	0.0	0.4	0.1	0.0	1.6	2.1	0.6	0.8	4.6	0.0	67.6	6.7	1.3	0.1	1.1	1.5	0.5	1.3	0.7	67.1	6272.7	0.0	8.4	5.3	0.0	0.0	108.0	2.8	2.1	1.5	0.3	0.0	1.9	0.4	0.7	0.0	2.0	2.2	3.2	0.0	2.6	0.3	0.6	0.0	0.6	2.2	5.8	0.0	0.2	0.6	4.1	4.2	2.0	7.5	0.1	5.7	0.2	0.0	0.0
CYP2F1	CYP2F	ENSG00000197446	"Cytochrome P450 family 2 subfamily F member 1"	P24903	19	41114432-41128381	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"lung: 1.4;salivary gland: 1.0;testis: 2.1"	"Cell type enriched"	"Detected in some"	4	"Club cells: 67.4"	"Cancer enhanced"	"Detected in some"		"testis cancer: 1.0"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in single"	7	"HMC-1: 2.3"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"								"Intracellular and membrane"	NA	NA				"Cluster 71: Testis - DNA repair"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"				"unprognostic (2.04e-1)"	"unprognostic (8.79e-2)"	"unprognostic (4.63e-1)"	"unprognostic (4.60e-2)"	"unprognostic (2.54e-1)"	"unprognostic (7.29e-3)"		"unprognostic (6.23e-3)"		"unprognostic (2.87e-2)"	"unprognostic (3.91e-2)"		"unprognostic (1.58e-6)"	"unprognostic (1.59e-1)"	"unprognostic (1.29e-1)"	"unprognostic (9.90e-2)"	"unprognostic (1.50e-1)"	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.1	0.0	0.0	0.0	0.0	0.1	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	9.2	0.0	0.0	0.0	0.0	0.5	0.0	67.4	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.4	0.1	0.4	0.2	0.0	0.0	0.1	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	4.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	16.5	0.0	0.0	0.0	1.6	8.0	5.3	1.5	0.0	0.0	0.6	0.0	0.0	0.1
CYP2J2		ENSG00000134716	"Cytochrome P450 family 2 subfamily J member 2"	P51589	1	59893308-59926773	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Isomerase, Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 89.7;intestine: 83.4;liver: 146.2"	"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 91.4;Cytotrophoblasts: 116.2;Hepatocytes: 58.3;Oligodendrocytes: 68.5;Proximal enterocytes: 134.6;Syncytiotrophoblasts: 240.9"	"Cancer enhanced"	"Detected in many"		"renal cancer: 32.0"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6"	"Low lineage specificity"	"Detected in single"			"Group enriched"	"Detected in some"	5	"OE19: 16.9;RT4: 62.3;SK-BR-3: 16.4"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"								"Intracellular and membrane"	NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 15: Liver - Metabolism"	"Cluster 15: RT4 - Unknown function"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"				"unprognostic (3.53e-2)"	"unprognostic (1.22e-2)"	"unprognostic (1.35e-2)"	"unprognostic (1.99e-2)"	"unprognostic (2.51e-2)"	"unprognostic (2.28e-1)"	"unprognostic (1.61e-1)"	"unprognostic (3.16e-1)"	"unprognostic (1.15e-1)"	"unprognostic (2.84e-2)"	"unprognostic (7.29e-2)"	"unprognostic (2.66e-1)"	"prognostic unfavorable (5.54e-7)"	"unprognostic (4.96e-1)"	"unprognostic (8.45e-2)"	"unprognostic (4.25e-1)"	"unprognostic (9.70e-2)"	1.2	0.4	18.3	1.2	22.1	0.1	9.3	23.6	19.1	2.3	8.4	19.0	34.1	1.0	0.8	13.1	0.9	2.0	89.7	14.7	19.4	3.0	146.2	1.4	0.2	20.7	20.7	0.0	2.2	0.0	0.9	22.3	18.9	3.3	21.3	3.5	14.5	0.7	25.3	8.9	83.4	1.8	20.2	0.1	4.7	0.6	28.0	0.5	0.1	6.4	0.7	5.8	3.6	21.8	0.2	0.0	0.1	0.0	0.0	0.3	0.0	0.0	2.7	0.1	1.2	0.3	2.8	0.0	0.8	0.0	3.5	0.9	0.0	0.9	0.0	0.0	1.7	0.0	0.0	0.5	0.0	0.0	0.1	0.5	0.9	0.0	0.0	0.0	0.0	2.2	0.0	0.0	0.6	3.2	0.0	0.0	1.5	16.9	2.6	0.0	6.3	0.0	3.4	62.3	0.9	3.8	0.1	16.4	0.6	0.1	4.1	0.0	0.0	2.2	2.5	0.0	0.9	1.9	0.1	0.0	0.5	0.0	6.9	0.0	0.0	0.0	0.1	0.0	0.6	0.8	0.3	0.2	0.0	0.4	2.9	2.6	0.0	0.4	0.0	0.6	0.0	0.4	18.3	22.1	23.6	19.1	14.7	19.4	20.7	20.7	18.9	20.2	28.0	21.8	0.0	3.2	4.1	35.6	0.7	0.4	1.7	5.5	7.4	0.0	5.1	3.0	91.4	11.5	28.9	0.0	0.0	116.2	0.1	26.4	0.0	9.5	22.7	3.1	1.7	1.3	9.0	0.0	0.1	0.9	9.3	2.3	4.1	7.7	0.0	1.5	0.0	58.3	7.0	0.0	0.4	18.7	6.1	0.8	0.3	23.3	0.0	0.2	0.0	1.9	0.6	12.5	0.0	29.7	68.5	2.0	18.1	0.0	0.3	1.5	134.6	2.5	20.1	0.9	0.0	0.7	1.0	0.3	0.2	7.3	2.3	240.9	0.2	0.4	24.1	2.1
CYP2R1		ENSG00000186104	"Cytochrome P450 family 2 subfamily R member 1"	Q6VVX0	11	14877440-14892231	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		"Monooxygenase, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in many"	5	"Early spermatids: 176.3;Late spermatids: 106.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"Karpas-707: 26.0"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA042949	Approved				"Intracellular and membrane"	NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 24: Salivary gland - Salivary secretion"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 23: Spermatids - Flagellum & Golgi organization"			"HPA042949: AB_2678237"	"unprognostic (1.62e-2)"	"unprognostic (1.82e-2)"	"unprognostic (5.90e-2)"	"unprognostic (1.63e-3)"	"unprognostic (2.67e-1)"	"unprognostic (2.19e-1)"	"unprognostic (3.23e-2)"	"unprognostic (7.73e-2)"	"unprognostic (1.70e-1)"	"unprognostic (3.90e-2)"	"unprognostic (2.25e-1)"	"unprognostic (1.21e-1)"	"prognostic unfavorable (2.86e-4)"	"unprognostic (1.01e-1)"	"unprognostic (1.81e-1)"	"unprognostic (1.46e-1)"	"unprognostic (1.44e-2)"	2.5	1.8	1.6	3.1	1.9	3.0	4.1	4.9	2.4	2.6	0.5	3.7	4.6	2.2	3.2	4.6	1.8	1.6	2.2	1.6	2.1	1.8	2.2	2.5	3.0	1.7	1.5	2.0	5.2	1.5	2.6	1.0	1.8	2.8	3.3	3.3	4.5	1.4	2.8	6.9	4.4	1.5	1.5	3.0	5.0	4.3	1.6	2.4	1.9	1.6	2.9	3.0	3.3	2.3	6.1	3.7	3.6	1.5	1.5	2.5	0.0	2.1	1.1	1.2	1.3	4.3	6.8	7.6	1.6	0.4	4.7	0.0	1.2	2.8	0.5	6.3	5.8	3.4	4.7	0.3	5.4	5.9	3.4	2.4	10.6	0.0	4.4	1.1	1.4	9.3	5.1	26.0	0.8	1.6	6.5	11.9	3.4	4.4	3.5	4.6	2.6	11.6	1.4	0.7	3.0	4.7	4.5	5.4	5.2	2.3	4.0	2.2	3.8	3.6	4.4	2.2	2.7	12.8	16.1	9.0	5.0	7.6	3.3	2.4	2.0	1.6	3.0	1.9	4.7	1.6	2.5	1.9	1.7	2.8	3.5	3.0	0.3	2.1	2.3	2.0	3.6	1.2	1.6	1.9	4.9	2.4	1.6	2.1	1.7	1.5	1.8	1.5	1.6	2.3	4.4	12.8	4.8	8.5	15.4	5.9	13.9	9.3	12.5	1.9	7.0	5.8	4.3	8.6	7.4	5.5	6.2	0.3	9.8	10.1	5.9	8.1	176.3	1.9	3.3	6.7	6.7	4.6	13.1	16.9	0.2	4.4	14.8	3.9	3.8	7.8	5.0	6.0	5.9	1.7	18.4	5.5	0.0	7.6	12.6	106.7	2.1	7.7	14.2	13.1	6.1	5.0	13.4	14.6	13.3	11.3	2.9	4.1	11.9	6.4	12.6	6.2	2.8	5.0	13.1	3.2	4.9	23.8	20.2	20.4	6.7	0.0	16.4	6.7	8.8	6.1
CYP2U1	"SPG49, SPG56"	ENSG00000155016	"Cytochrome P450 family 2 subfamily U member 1"	Q7Z449	4	107931549-107953461	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"		"Monooxygenase, Oxidoreductase"	"Disease variant, Hereditary spastic paraplegia, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	8	"lymphoid tissue: 84.9"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 30.2;Inhibitory neurons: 34.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"non-classical monocyte: 2.8"	"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041622, HPA046754, HPA064827"	Uncertain		Approved	"Nucleoplasm,Golgi apparatus,Vesicles"		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 63: T-cells - Adaptive immune response"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 50: Fibroblasts - ECM organization"	"Golgi apparatus"	"Nucleoplasm, Vesicles"	"HPA041622: AB_2677583, HPA046754: AB_2679787, HPA064827: AB_2685362"	"unprognostic (3.54e-1)"	"unprognostic (2.45e-1)"	"unprognostic (3.08e-1)"	"unprognostic (2.84e-1)"	"unprognostic (5.16e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.36e-2)"	"unprognostic (1.20e-3)"	"unprognostic (3.19e-1)"	"unprognostic (8.97e-3)"	"unprognostic (5.41e-3)"	"unprognostic (3.02e-1)"	"prognostic favorable (2.75e-5)"	"prognostic unfavorable (6.97e-4)"	"unprognostic (1.19e-1)"	"unprognostic (1.17e-2)"	"unprognostic (1.11e-1)"	7.7	6.4	6.6	4.0	8.3	0.5	4.5	7.6	7.3	5.1	10.1	5.8	3.4	6.6	3.6	3.5	7.8	5.6	7.7	6.5	8.7	5.3	5.9	5.7	6.3	9.0	7.9	9.5	2.3	10.7	4.7	2.4	8.2	9.9	3.9	5.8	3.4	8.7	3.6	2.7	4.7	10.2	8.1	7.6	3.2	3.0	8.0	84.9	3.6	7.2	4.7	4.7	3.8	9.5	4.0	1.9	5.2	9.5	28.6	13.4	0.8	16.8	25.3	10.2	15.7	0.1	2.5	10.8	1.1	10.1	7.8	0.2	8.1	6.4	15.4	3.0	2.5	2.3	3.5	0.5	11.3	3.2	0.0	15.3	5.3	4.7	3.2	20.8	4.0	12.0	0.1	5.0	8.4	2.9	11.8	0.0	5.4	0.4	4.7	6.5	6.3	0.1	3.3	6.7	10.0	7.6	4.2	7.3	18.6	4.3	3.6	1.5	10.6	6.5	0.8	9.3	6.9	21.1	21.2	3.4	5.5	0.0	7.4	0.0	0.1	0.3	0.4	0.5	0.3	0.8	0.3	0.4	0.9	1.1	0.7	0.5	0.0	0.7	2.8	1.1	0.0	0.2	6.6	8.3	7.6	7.3	6.5	8.7	9.0	7.9	8.2	8.1	8.0	9.5	5.5	3.2	3.9	18.6	12.9	1.1	4.6	2.2	15.4	4.1	2.8	5.8	6.2	1.5	2.4	9.2	4.2	0.4	10.1	1.4	0.0	0.9	13.2	6.9	6.3	5.8	3.0	1.7	30.2	2.0	0.3	12.6	3.1	6.2	4.5	2.5	8.6	7.3	2.3	1.7	34.3	1.2	0.0	6.2	3.3	9.5	17.7	4.7	19.6	5.6	3.7	9.5	1.0	20.1	12.1	0.4	0.1	17.7	4.2	1.5	9.9	3.0	8.6	3.1	0.0	20.0	8.1	1.0	4.2	2.0	1.4	0.3	3.6	5.1	3.1	0.8
CYP39A1		ENSG00000146233	"Cytochrome P450 family 39 subfamily A member 1"	Q9NYL5	6	46549580-46652830	"Enzymes, Metabolic proteins, Predicted membrane proteins"	"Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	4	"liver: 99.2"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 62.9;Late spermatids: 20.1"	"Cancer enhanced"	"Detected in many"		"prostate cancer: 11.9"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"Daudi: 6.5;hTCEpi: 13.6;OE19: 6.1;SiHa: 8.4;U-698: 10.4"	"Region enhanced"	"Detected in all"		"olfactory bulb: 22.9"	"Low region specificity"	"Detected in all"									NA	NA				"Cluster 85: Liver - Metabolism"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 2: Hepatocytes - Metabolism"				"unprognostic (1.33e-1)"	"unprognostic (1.62e-2)"	"unprognostic (8.46e-3)"	"unprognostic (5.89e-2)"	"unprognostic (1.06e-1)"	"unprognostic (2.08e-1)"	"unprognostic (1.03e-1)"	"unprognostic (5.78e-2)"	"unprognostic (1.61e-1)"	"unprognostic (4.99e-2)"	"unprognostic (7.33e-2)"	"unprognostic (6.11e-2)"	"prognostic favorable (1.86e-4)"	"unprognostic (1.54e-1)"	"unprognostic (5.48e-2)"	"unprognostic (1.43e-1)"	"unprognostic (1.20e-1)"	3.0	2.5	2.1	1.0	2.7	0.0	5.4	3.5	2.9	3.7	5.3	2.7	0.8	3.6	21.0	3.3	4.1	6.3	3.9	2.0	2.1	5.7	99.2	3.3	0.5	2.3	2.3	11.5	5.7	15.3	2.9	0.4	2.1	14.8	3.6	4.1	23.5	2.6	0.6	15.9	1.6	2.4	2.4	0.7	2.8	4.2	2.4	0.4	6.1	1.2	1.4	2.7	3.0	2.9	0.2	0.4	0.3	1.8	0.3	0.0	0.0	0.0	1.1	0.3	0.1	0.0	0.5	6.5	4.4	0.0	0.9	1.7	0.8	1.4	0.0	0.0	2.8	0.0	1.7	1.8	4.0	0.0	0.0	0.5	13.6	0.0	1.6	1.2	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.1	0.0	6.1	1.5	0.5	1.1	0.1	2.9	4.0	0.7	0.0	8.4	0.0	0.2	0.4	1.5	0.0	0.0	0.2	0.9	0.0	0.1	0.0	0.0	10.4	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.1	2.7	3.5	2.9	2.0	2.1	2.3	2.3	2.1	2.4	2.4	2.9	3.3	16.0	1.5	3.9	0.2	4.0	8.8	2.7	2.8	1.4	4.6	6.5	5.8	10.0	4.3	3.7	2.1	0.0	0.0	1.1	5.9	2.9	12.7	4.4	1.0	3.5	0.0	5.3	3.2	0.4	0.9	4.5	1.5	3.1	0.0	2.7	1.1	62.9	0.2	0.0	2.0	4.0	10.2	2.5	0.9	20.1	6.2	0.3	3.6	8.4	0.0	8.6	0.0	1.0	7.2	0.5	2.7	9.4	0.0	7.9	0.3	5.3	7.2	1.5	0.0	1.9	2.3	0.7	0.8	2.6	15.3	0.0	0.2	6.3	2.5	8.1
CYP3A4	CYP3A3	ENSG00000160868	"Cytochrome P450 family 3 subfamily A member 4"	P08684	7	99756960-99784248	"Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism"	"Monooxygenase, Oxidoreductase"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	4	"liver: 3796.2"	"Group enriched"	"Detected in some"	40	"Hepatocytes: 2612.9;Proximal enterocytes: 1685.2"	"Cancer enriched"	"Detected in some"	240	"liver cancer: 351.3"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"BEWO: 2.0;NB-4: 2.2;RPMI-8226: 3.4;SCLC-21H: 1.3;SH-SY5Y: 2.0"					"Low region specificity"	"Detected in all"			"CAB033671, HPA072245, HPA075539"	Enhanced		Approved	Vesicles,Cytosol		NA	NA				"Cluster 85: Liver - Metabolism"	"Cluster 24: NB-4 - Immune response"	"Cluster 2: Hepatocytes - Metabolism"	Cytosol	Vesicles	"CAB033671: AB_782375, HPA072245: , HPA075539: "	"unprognostic (4.55e-2)"	"unprognostic (8.95e-2)"	"unprognostic (8.08e-2)"	"unprognostic (1.63e-1)"	"unprognostic (5.89e-2)"	"unprognostic (5.37e-2)"	"unprognostic (7.07e-3)"	"unprognostic (9.09e-2)"	"unprognostic (8.27e-3)"	"unprognostic (4.92e-2)"	"unprognostic (3.78e-2)"	"unprognostic (6.42e-2)"	"unprognostic (1.89e-8)"	"unprognostic (2.59e-1)"	"unprognostic (1.75e-2)"	"unprognostic (9.79e-2)"	"unprognostic (6.82e-2)"	0.3	3.8	0.1	1.1	0.3	0.0	0.3	0.0	0.8	0.1	0.0	4.6	797.6	0.6	0.2	0.4	0.1	0.6	0.1	0.1	0.0	4.9	3796.2	0.1	0.9	0.0	0.0	0.1	43.4	0.0	1.0	0.0	0.0	0.2	2.2	0.4	0.3	0.0	2.4	1.9	853.0	0.0	0.0	0.1	1.1	1.0	0.1	0.4	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.1	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.6	0.1	0.1	0.0	0.8	0.1	0.0	0.6	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.1	2.2	0.2	0.0	0.0	0.0	0.8	3.4	0.0	0.1	1.3	2.0	0.1	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.7	0.0	0.3	0.0	0.4	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.3	0.0	0.8	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.0	2.2	0.4	0.8	0.2	0.0	0.0	0.0	0.0	0.4	32.9	0.0	0.0	0.0	0.3	0.0	5.6	0.0	0.1	0.4	0.0	0.0	1.4	0.0	26.7	0.6	0.9	0.0	0.0	0.0	0.1	0.0	0.0	30.0	2612.9	0.0	0.0	0.6	29.6	2.0	52.8	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.5	0.2	0.1	38.9	0.0	0.0	0.6	1685.2	3.0	0.0	0.0	0.0	0.1	0.0	0.1	0.9	0.0	0.9	0.1	2.3	0.5	16.1	1.1
CYP3A43		ENSG00000021461	"Cytochrome P450 family 3 subfamily A member 43"	Q9HB55	7	99828013-99866102	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	8	"liver: 44.7"	"Cell type enhanced"	"Detected in some"		"Astrocytes: 4.6;Early spermatids: 7.5;Excitatory neurons: 3.9;granulocytes: 2.5;Hepatocytes: 6.4;Late spermatids: 3.3;Spermatocytes: 2.4"	"Cancer enriched"	"Detected in single"	18	"liver cancer: 1.4"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"											"HPA066463, HPA072245, HPA075539"	Enhanced		Approved	Vesicles,Cytosol		NA	NA				"Cluster 85: Liver - Metabolism"		"Cluster 15: Hepatocytes - Hemostasis"	Cytosol	Vesicles	"HPA066463: AB_2685670, HPA072245: , HPA075539: "	"unprognostic (1.20e-3)"	"unprognostic (4.74e-2)"	"unprognostic (3.64e-3)"		"unprognostic (7.24e-2)"	"unprognostic (2.52e-1)"	"prognostic favorable (3.41e-4)"	"unprognostic (1.68e-2)"	"unprognostic (1.44e-1)"	"unprognostic (2.38e-1)"	"unprognostic (1.12e-1)"	"unprognostic (6.45e-2)"	"unprognostic (1.23e-2)"	"unprognostic (6.46e-2)"	"unprognostic (5.90e-2)"	"unprognostic (3.10e-1)"	"unprognostic (6.37e-4)"	0.1	0.0	0.0	0.0	0.1	0.2	0.2	0.0	0.8	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.0	0.1	0.1	0.1	0.0	0.2	44.7	0.1	0.1	0.0	0.0	0.1	5.7	0.0	0.0	0.0	0.0	0.6	0.1	0.5	0.2	0.1	0.3	0.2	0.1	0.2	0.0	0.1	0.1	0.8	0.0	0.1	0.1	0.2	0.1	0.0	0.0	0.3	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.2	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.1	0.3	0.3	0.0	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.1	0.3	0.0	0.1	0.1	0.0	0.3	0.1	0.0	0.1	0.1	0.1	0.2	0.0	0.1	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.8	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	4.6	0.0	0.3	0.4	0.0	0.0	0.4	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	7.5	0.0	0.0	0.2	0.0	0.0	3.9	0.0	0.0	0.3	0.0	0.0	2.5	0.0	0.0	6.4	0.1	1.7	1.9	0.0	0.0	0.6	1.9	3.3	0.0	0.2	0.0	1.0	0.0	0.2	0.0	0.5	1.7	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.3	0.0	0.7	0.1	2.4	0.3	0.0	0.3	0.0	0.4	0.0	0.0	0.2
CYP3A5	"CP35, P450PCN3, PCN3"	ENSG00000106258	"Cytochrome P450 family 3 subfamily A member 5"	P20815	7	99648194-99679998	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid metabolism, Steroid metabolism"	"Monooxygenase, Oxidoreductase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 177.7;liver: 276.1"	"Cell type enhanced"	"Detected in many"		"Cholangiocytes: 377.4;Distal enterocytes: 382.7;Gastric mucus-secreting cells: 506.6;Hepatocytes: 454.5;Paneth cells: 451.6;Proximal enterocytes: 1074.6;Urothelial cells: 380.4"	"Cancer enhanced"	"Detected in many"		"liver cancer: 38.5"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"CACO-2: 9.7;Hep G2: 7.9;OE19: 28.3"									"HPA072245, HPA075539"			Approved	Vesicles,Cytosol		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 21: OE19 - Mitochondria"	"Cluster 45: Enterocytes - Digestion"	Cytosol	Vesicles	"HPA072245: , HPA075539: "	"unprognostic (2.13e-1)"	"unprognostic (4.36e-2)"	"unprognostic (4.04e-2)"	"unprognostic (1.00e-1)"	"unprognostic (1.06e-2)"	"unprognostic (2.73e-1)"	"prognostic favorable (3.72e-5)"	"unprognostic (1.37e-3)"	"unprognostic (1.21e-2)"	"unprognostic (7.29e-3)"	"unprognostic (3.85e-1)"	"unprognostic (4.05e-2)"	"unprognostic (1.46e-1)"	"unprognostic (1.00e-1)"	"unprognostic (1.93e-1)"	"unprognostic (2.39e-4)"	"unprognostic (6.58e-3)"	3.3	14.4	0.1	3.8	0.4	0.6	6.5	0.8	0.9	5.1	0.4	28.4	127.3	3.1	3.0	22.1	3.1	32.7	1.0	0.3	0.0	10.6	276.1	9.2	1.4	0.6	0.0	0.8	47.0	0.0	0.9	0.4	0.4	21.6	21.0	0.7	2.9	5.7	0.9	20.5	177.7	1.1	0.0	0.8	86.5	0.4	0.0	2.1	1.0	0.0	3.2	10.4	13.1	0.5	1.6	3.3	1.6	1.9	0.4	0.6	0.5	1.5	0.0	0.0	0.0	9.7	7.4	1.0	1.5	0.0	1.2	1.2	0.0	0.0	0.0	1.8	1.2	1.2	0.7	7.9	0.1	2.0	0.6	0.0	2.1	0.0	0.0	1.4	0.0	0.9	3.3	2.0	0.0	0.3	2.6	3.8	0.4	28.3	0.8	0.6	1.6	2.2	0.4	1.5	1.2	1.7	0.9	0.8	3.2	1.6	0.5	0.7	1.2	1.8	1.6	1.6	1.2	1.0	2.6	1.7	1.6	2.6	1.5	0.4	0.3	0.4	0.4	0.3	0.9	0.2	0.6	0.6	0.2	0.1	0.4	0.5	0.5	0.4	0.2	0.3	0.5	0.2	0.1	0.4	0.8	0.9	0.3	0.0	0.6	0.0	0.4	0.0	0.0	0.5	0.9	12.8	14.8	1.3	4.8	46.1	112.7	31.0	59.7	13.7	1.1	0.4	1.3	377.4	27.3	3.7	12.5	1.7	1.7	382.7	0.0	63.4	2.0	3.1	2.2	6.3	54.6	21.7	8.6	50.7	1.2	8.5	506.6	10.3	10.1	1.8	8.2	454.5	0.6	8.4	11.0	140.5	6.1	9.5	4.5	0.5	2.5	4.1	3.6	2.8	4.9	4.0	10.3	7.1	6.5	80.1	451.6	2.6	6.4	156.3	1074.6	10.8	12.1	21.6	0.0	2.5	3.4	15.1	6.4	107.3	59.0	1.5	7.5	3.1	139.8	380.4
CYP3A7	"CP37, P450-HFLA"	ENSG00000160870	"Cytochrome P450 family 3 subfamily A member 7"	P24462	7	99705036-99735196	"Enzymes, Metabolic proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	36	"liver: 304.9"	"Group enriched"	"Detected in some"	17	"Cholangiocytes: 85.8;Hepatocytes: 60.5"	"Cancer enriched"	"Detected in some"	43	"liver cancer: 38.0"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"BJ hTERT+: 1.3;Hep G2: 2.5;HHSteC: 1.4"									"HPA072245, HPA075539"			Approved	Vesicles,Cytosol		NA	NA				"Cluster 60: Liver - Hemostasis & Lipid metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 15: Hepatocytes - Hemostasis"	Cytosol	Vesicles	"HPA072245: , HPA075539: "	"unprognostic (8.10e-3)"	"unprognostic (1.45e-1)"	"unprognostic (3.12e-1)"	"unprognostic (5.47e-2)"	"unprognostic (1.73e-1)"	"unprognostic (1.44e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.50e-1)"	"unprognostic (1.34e-2)"	"unprognostic (8.28e-2)"	"unprognostic (8.18e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.06e-11)"	"unprognostic (2.02e-2)"	"unprognostic (5.87e-2)"	"unprognostic (2.97e-1)"	"unprognostic (1.34e-3)"	0.2	0.9	0.0	0.0	0.0	0.0	2.4	0.0	0.2	0.0	0.0	0.2	0.5	0.3	0.3	0.1	0.0	6.5	0.0	0.0	0.1	8.5	304.9	2.4	0.0	0.1	0.0	0.1	0.4	0.0	0.0	0.0	0.0	0.9	0.2	0.0	0.1	0.1	0.0	0.2	1.8	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.9	0.6	0.0	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.1	2.5	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.9	0.0	0.0	0.0	0.0	0.1	85.8	0.3	0.0	0.0	0.0	0.0	0.0	1.9	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	3.3	60.5	0.1	0.0	0.0	0.0	0.0	2.8	0.0	0.0	0.0	0.0	3.6	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.3	3.8	4.3	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.4	0.1	1.3	0.0	0.2
CYP46A1	CYP46	ENSG00000036530	"Cytochrome P450 family 46 subfamily A member 1"	Q9Y6A2	14	99684298-99727301	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"brain: 96.2"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 58.1;Cone photoreceptor cells: 66.7;Excitatory neurons: 53.0;Inhibitory neurons: 41.6;Rod photoreceptor cells: 28.4"	"Cancer enriched"	"Detected in single"	5	"glioma: 1.7"	"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in single"	23	"plasmacytoid DC: 3.4"	"Lineage enriched"	"Detected in single"	23	"dendritic cells: 3.4"	"Group enriched"	"Detected in some"	4	"AF22: 2.4;U-937: 6.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"								"Intracellular and membrane"	NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 65: Brain - Ion transport"	"Cluster 32: U-937 - Innate immune response"	"Cluster 9: Photoreceptor cells - Phototransduction"				"unprognostic (2.16e-1)"	"unprognostic (4.30e-1)"	"unprognostic (2.50e-5)"	"unprognostic (9.48e-5)"	"unprognostic (1.15e-1)"	"unprognostic (5.92e-2)"	"unprognostic (3.45e-2)"	"unprognostic (1.06e-1)"	"unprognostic (5.37e-2)"	"unprognostic (4.01e-2)"	"unprognostic (1.32e-5)"	"unprognostic (5.21e-2)"	"unprognostic (2.44e-4)"	"unprognostic (5.97e-4)"	"unprognostic (1.59e-1)"	"unprognostic (1.15e-2)"	"unprognostic (3.88e-3)"	1.9	2.0	45.7	0.3	96.2	0.0	0.8	20.1	66.7	1.4	17.5	0.7	0.2	1.5	0.9	0.2	1.0	0.4	4.7	52.7	34.0	1.4	1.3	0.6	0.6	25.3	32.0	1.6	2.1	1.9	16.6	0.0	26.2	1.4	0.2	5.1	1.4	0.6	1.1	0.4	0.5	0.8	23.5	0.2	0.7	2.5	38.2	0.4	1.7	0.5	0.1	0.9	0.7	39.0	0.0	0.0	2.4	0.5	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.2	0.3	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.1	0.0	0.8	0.0	0.1	0.0	0.6	0.0	0.0	0.1	0.0	0.3	0.1	0.0	0.0	0.1	0.0	0.2	0.0	0.2	0.0	0.0	0.8	0.0	1.1	0.0	0.0	0.0	0.6	0.0	0.1	0.0	0.0	0.1	6.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.4	0.0	0.0	45.7	96.2	20.1	66.7	52.7	34.0	25.3	32.0	26.2	23.5	38.2	39.0	3.5	3.2	6.0	58.1	0.7	1.7	6.4	0.0	1.2	11.5	1.8	3.3	7.0	2.8	1.8	1.8	66.7	0.2	8.7	0.0	1.9	0.2	0.7	0.9	5.0	7.6	0.0	0.0	53.0	1.1	0.3	4.0	0.5	0.6	1.3	2.1	2.9	3.4	0.6	8.4	41.6	0.0	0.0	2.1	3.0	1.3	4.7	0.9	3.6	6.5	1.1	20.8	0.0	23.6	11.8	0.1	0.1	4.1	2.2	4.1	0.0	7.4	0.9	28.4	0.0	8.1	3.9	9.4	5.3	0.0	1.4	0.1	1.5	2.7	0.1	3.5
CYP4A11	"CYP4A2, CYP4AII"	ENSG00000187048	"Cytochrome P450 family 4 subfamily A member 11"	Q02928	1	46929177-46941484	"Enzymes, Metabolic proteins, Predicted membrane proteins"	"Fatty acid metabolism, Lipid metabolism"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	333	"kidney: 218.8;liver: 857.1"	"Cell type enriched"	"Detected in some"	5	"Hepatocytes: 563.8"	"Cancer enriched"	"Detected in some"	5	"liver cancer: 73.4"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"																	NA	NA				"Cluster 85: Liver - Metabolism"		"Cluster 67: Proximal tubular cells - Tubular reabsorption"				"unprognostic (9.05e-2)"	"unprognostic (4.98e-2)"		"unprognostic (4.43e-2)"	"unprognostic (4.11e-1)"	"unprognostic (7.81e-5)"	"unprognostic (5.10e-3)"	"unprognostic (1.16e-2)"	"unprognostic (1.83e-2)"	"unprognostic (1.92e-2)"	"unprognostic (1.90e-1)"	"unprognostic (1.12e-1)"	"unprognostic (4.59e-2)"	"unprognostic (5.86e-2)"	"unprognostic (1.96e-1)"	"unprognostic (3.00e-3)"	"unprognostic (1.68e-2)"	0.3	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.1	1.6	0.0	1.4	0.0	0.1	1.1	0.1	0.0	0.1	218.8	857.1	0.0	0.0	0.1	0.3	0.0	0.2	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	1.3	0.0	0.0	0.3	0.4	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.1	0.3	0.1	0.0	0.1	0.0	0.2	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.2	32.9	0.0	7.3	0.0	0.0	0.0	0.0	17.6	0.0	0.5	0.8	0.0	0.5	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.4	563.8	0.0	0.0	0.1	0.0	0.0	7.3	0.2	0.8	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	0.0	4.1	108.7	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.2	0.0
CYP4A22		ENSG00000162365	"Cytochrome P450 family 4 subfamily A member 22"	Q5TCH4	1	47137435-47149735	"Enzymes, Metabolic proteins, Predicted membrane proteins"		"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	7	"liver: 214.2"	"Cell type enriched"	"Detected in some"	9	"Hepatocytes: 143.0"	"Cancer enriched"	"Detected in some"	13	"liver cancer: 20.0"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"RH-30: 1.2"															NA	NA				"Cluster 85: Liver - Metabolism"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 2: Hepatocytes - Metabolism"				"unprognostic (5.34e-2)"	"unprognostic (1.24e-1)"		"unprognostic (3.19e-2)"			"unprognostic (2.88e-3)"	"unprognostic (2.76e-3)"		"unprognostic (1.50e-3)"	"unprognostic (2.21e-1)"	"unprognostic (2.75e-1)"	"unprognostic (1.93e-2)"	"unprognostic (5.29e-3)"	"unprognostic (1.02e-1)"	"unprognostic (1.71e-1)"	"unprognostic (8.59e-4)"	0.4	0.0	0.2	0.0	0.0	0.0	0.3	0.0	0.7	0.0	0.0	0.0	0.1	0.0	3.7	0.0	0.0	0.0	0.1	0.1	0.0	32.9	214.2	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.3	0.1	0.0	0.1	0.3	0.1	0.0	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	1.2	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.5	0.1	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.7	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.3	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	2.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.4	0.0	0.2	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	143.0	0.0	0.0	0.2	0.0	0.0	1.9	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	15.6	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0
CYP4B1		ENSG00000142973	"Cytochrome P450 family 4 subfamily B member 1"	P13584	1	46757838-46819413	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lung: 242.2"	"Group enriched"	"Detected in many"	4	"Alveolar cells type 1: 1227.5;Club cells: 405.1;Respiratory ciliated cells: 763.9"	"Cancer enhanced"	"Detected in many"		"urothelial cancer: 56.9"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	8	"RT4: 286.7"	"Low region specificity"	"Detected in single"			"Not detected"	"Not detected"			HPA004331	Approved		Supported	Vesicles		NA	NA				"Cluster 82: Adipose tissue - ECM organization"	"Cluster 15: RT4 - Unknown function"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"	Vesicles		"HPA004331: AB_1078616"	"unprognostic (2.29e-2)"	"prognostic favorable (5.99e-4)"	"unprognostic (7.01e-2)"	"unprognostic (1.11e-1)"	"unprognostic (2.28e-1)"	"unprognostic (8.31e-2)"	"unprognostic (1.16e-2)"	"unprognostic (1.98e-2)"	"unprognostic (2.65e-1)"	"unprognostic (2.59e-1)"	"unprognostic (6.12e-2)"	"unprognostic (5.46e-2)"	"unprognostic (7.33e-2)"	"unprognostic (1.80e-1)"	"unprognostic (1.15e-1)"	"unprognostic (1.22e-3)"	"unprognostic (6.69e-3)"	81.8	4.9	0.3	0.0	0.3	0.0	62.0	0.2	0.6	13.4	1.2	14.6	1.3	9.5	1.7	44.0	48.0	0.5	40.2	0.2	0.3	2.4	0.1	242.2	0.5	0.3	0.3	1.7	3.4	0.7	9.3	1.2	0.3	22.7	0.7	0.0	16.6	15.8	24.0	42.7	15.2	0.1	0.3	0.4	11.5	0.5	0.4	3.1	22.3	24.6	15.2	81.7	30.5	0.3	0.0	0.0	0.0	0.0	20.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	16.5	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.2	0.0	0.0	0.0	0.0	0.0	0.0	35.6	0.0	0.1	0.0	0.3	0.0	0.2	0.0	0.1	0.0	0.0	0.0	286.7	0.1	0.0	0.0	11.4	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.3	0.2	0.6	0.2	0.3	0.3	0.3	0.3	0.3	0.4	0.3	60.8	1227.5	89.3	0.0	0.0	0.5	139.6	111.5	36.5	0.0	2.0	1.5	6.4	1.5	405.1	0.0	0.0	1.2	0.0	0.0	0.0	0.0	1.7	93.8	12.5	23.5	0.0	0.0	0.1	0.0	0.2	47.9	1.1	8.5	6.3	0.0	1.4	0.0	0.6	0.0	0.1	0.0	48.8	0.0	0.3	0.9	0.6	1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.1	6.9	0.0	1.1	763.9	0.0	0.0	3.0	23.3	0.1	0.1	71.4	4.1	0.8	1.8	0.0	0.0	163.0
CYP4F11		ENSG00000171903	"Cytochrome P450 family 4 subfamily F member 11"	Q9HBI6	19	15912367-15934867	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 23.9;liver: 72.3"	"Cell type enhanced"	"Detected in many"		"Ductal cells: 15.6;Hepatocytes: 62.9;Prostatic glandular cells: 36.3;Urothelial cells: 26.1"	"Cancer enhanced"	"Detected in many"		"liver cancer: 25.7"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"A-431: 13.1;CAPAN-2: 50.4;EFO-21: 18.5;Hep G2: 25.0;RPMI-8226: 13.5;RT4: 15.2"									"HPA017265, CAB033648, HPA058960"	Enhanced				"Intracellular and membrane"	NA	NA				"Cluster 85: Liver - Metabolism"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 15: Hepatocytes - Hemostasis"			"CAB033648: AB_2088410, HPA017265: AB_1847451, HPA058960: AB_2683862"	"prognostic favorable (4.05e-4)"	"unprognostic (4.12e-2)"	"unprognostic (1.79e-1)"	"unprognostic (5.99e-2)"	"unprognostic (5.92e-3)"	"unprognostic (1.06e-2)"	"unprognostic (1.24e-1)"	"unprognostic (1.65e-1)"	"unprognostic (2.33e-1)"	"unprognostic (1.19e-1)"	"prognostic unfavorable (9.28e-4)"	"unprognostic (4.44e-2)"	"unprognostic (9.50e-3)"	"unprognostic (2.14e-2)"	"unprognostic (2.24e-1)"	"unprognostic (2.78e-2)"	"unprognostic (4.64e-2)"	0.3	2.9	5.2	0.6	5.3	0.6	2.1	5.1	5.3	1.6	0.0	3.5	10.7	0.5	16.4	13.0	3.0	18.7	0.2	4.3	5.5	6.4	72.3	0.6	0.4	9.3	9.6	0.1	5.1	0.1	0.5	0.1	6.3	3.8	2.6	1.6	3.8	4.3	0.5	1.0	23.9	0.1	4.8	1.0	4.1	1.1	6.6	0.0	3.0	0.0	0.9	5.7	3.4	5.0	13.1	2.4	0.0	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	50.4	0.1	18.5	0.0	10.5	1.5	0.0	6.6	0.0	0.0	0.1	0.1	4.2	25.0	0.0	0.4	0.1	0.0	0.4	0.0	0.0	0.0	0.0	0.1	0.2	10.0	0.0	1.9	0.1	0.3	0.1	11.4	0.0	0.1	0.1	13.5	3.4	15.2	0.1	0.1	0.2	0.1	0.1	0.1	0.0	0.0	0.1	0.1	1.8	0.2	0.2	0.1	0.6	0.2	0.4	1.5	0.1	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	5.2	5.3	5.1	5.3	4.3	5.5	9.3	9.6	6.3	4.8	6.6	5.0	0.1	0.0	0.0	9.1	0.2	0.1	7.7	5.3	0.0	0.0	1.4	1.7	0.4	10.0	4.4	9.2	0.0	0.0	0.0	6.9	1.9	15.6	0.0	2.8	0.6	0.3	1.2	2.7	0.0	11.5	0.0	0.3	0.0	4.4	0.0	0.3	0.4	62.9	0.0	0.0	0.0	2.0	2.0	2.4	0.0	0.1	0.3	0.4	0.0	0.0	0.0	3.0	0.0	0.0	0.8	9.2	3.2	0.0	0.0	36.3	11.7	8.3	7.6	0.1	0.0	0.6	0.6	0.0	0.0	0.5	0.3	0.0	0.1	0.1	2.7	26.1
CYP4F12		ENSG00000186204	"Cytochrome P450 family 4 subfamily F member 12"	Q9HCS2	19	15673018-15697174	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Fatty acid metabolism, Lipid metabolism"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 41.5;liver: 40.1"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 58.8;Gastric mucus-secreting cells: 57.6;Paneth cells: 51.9;Proximal enterocytes: 125.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	54	"basophil: 6.1;eosinophil: 14.8"	"Lineage enriched"	"Detected in single"	88	"granulocytes: 14.8"	"Cell line enhanced"	"Detected in some"		"CAPAN-2: 17.6;HaCaT: 32.0;Hep G2: 9.8;Karpas-707: 20.9;OE19: 46.3"									HPA058960	Approved					NA	NA			"Cluster 49: Eosinophils - Unknown function"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 45: Enterocytes - Digestion"			"HPA058960: AB_2683862"	"unprognostic (4.30e-4)"	"prognostic favorable (1.21e-4)"	"unprognostic (1.86e-1)"	"unprognostic (1.48e-2)"	"unprognostic (1.37e-2)"	"unprognostic (5.32e-3)"	"unprognostic (1.84e-3)"	"unprognostic (9.13e-2)"	"unprognostic (9.11e-2)"	"unprognostic (2.50e-1)"	"unprognostic (4.32e-2)"	"unprognostic (1.47e-1)"	"unprognostic (1.66e-3)"	"unprognostic (6.20e-2)"	"unprognostic (5.45e-2)"	"unprognostic (3.17e-1)"	"prognostic favorable (2.33e-4)"	3.2	1.1	0.6	1.2	0.9	0.9	2.7	0.6	1.5	6.0	0.4	15.1	39.1	1.5	0.5	18.1	3.2	2.4	1.5	0.9	2.4	1.8	40.1	1.2	0.5	0.9	1.1	1.6	0.3	0.0	0.5	0.5	1.1	5.0	7.8	0.1	4.3	1.0	0.6	21.1	41.5	1.9	0.7	1.0	12.0	0.2	0.7	0.8	0.9	0.9	2.6	10.5	11.2	1.9	0.0	4.3	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.1	17.6	0.5	0.0	0.0	0.3	32.0	0.0	0.0	0.0	2.0	0.0	0.0	1.7	9.8	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	20.9	0.0	0.0	0.0	0.1	0.0	46.3	0.0	0.0	0.0	0.2	0.0	1.8	0.0	0.1	6.7	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	6.1	0.0	14.8	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.6	0.9	0.6	1.5	0.9	2.4	0.9	1.1	1.1	0.7	0.7	1.9	6.3	0.0	1.8	2.6	0.5	14.0	10.0	8.3	13.1	0.0	0.5	0.3	1.0	5.7	7.1	0.0	0.0	0.1	0.0	58.8	0.0	0.6	1.6	0.2	0.1	3.0	7.8	8.0	0.2	0.0	0.1	3.8	57.6	0.3	0.0	0.0	1.4	30.3	0.4	0.0	0.2	24.8	2.0	0.9	1.6	3.2	4.1	0.3	1.8	0.0	0.0	2.7	0.0	0.0	0.4	1.9	51.9	1.2	0.2	3.5	125.3	2.2	4.9	0.1	0.0	0.3	2.5	0.4	0.1	20.5	21.2	0.3	0.5	0.1	29.6	24.8
CYP4F2		ENSG00000186115	"Cytochrome P450 family 4 subfamily F member 2"	P78329	19	15878023-15898077	"Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Fatty acid metabolism, Lipid metabolism"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"intestine: 80.2;kidney: 40.9;liver: 166.7"	"Group enriched"	"Detected in some"	4	"Hepatocytes: 139.7;Proximal enterocytes: 204.6"	"Cancer enriched"	"Detected in some"	9	"liver cancer: 29.6"	"Not detected"	"Not detected"			"Immune cell enriched"	"Detected in single"	19	"basophil: 8.1"	"Lineage enriched"	"Detected in single"	82	"granulocytes: 8.1"	"Cell line enriched"	"Detected in single"	4	"Hep G2: 3.8"					"Low region specificity"	"Detected in all"			"HPA014048, HPA017265, HPA058960"	Supported				"Intracellular and membrane"	NA	NA			"Cluster 34: Basophils - Unknown function"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 2: Hepatocytes - Metabolism"			"HPA014048: AB_1847452, HPA017265: AB_1847451, HPA058960: AB_2683862"	"unprognostic (7.46e-3)"	"unprognostic (3.58e-1)"	"unprognostic (3.01e-1)"	"unprognostic (9.39e-2)"	"unprognostic (1.74e-1)"	"unprognostic (2.87e-2)"	"unprognostic (4.55e-3)"	"unprognostic (6.52e-2)"	"unprognostic (2.05e-1)"	"unprognostic (4.64e-2)"	"unprognostic (9.82e-2)"	"unprognostic (2.92e-1)"	"unprognostic (8.69e-4)"	"unprognostic (3.24e-1)"	"unprognostic (1.89e-1)"		"unprognostic (7.79e-3)"	0.0	0.0	0.1	0.1	0.1	1.1	0.2	0.1	0.3	0.1	0.5	2.2	79.9	0.0	25.8	0.2	0.0	3.3	0.0	0.2	0.1	40.9	166.7	0.0	0.1	0.1	0.4	0.0	0.3	0.0	0.0	0.0	0.1	6.6	0.9	0.0	0.0	0.1	0.0	0.8	80.2	0.0	0.3	0.1	0.6	0.5	0.1	0.0	0.0	0.0	0.0	0.3	0.4	0.3	0.0	0.0	0.1	0.0	0.0	0.0	0.8	0.0	0.0	0.0	0.1	0.3	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.1	3.8	0.0	0.4	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.6	0.0	0.0	0.0	0.1	0.2	0.3	0.0	0.1	0.2	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	8.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.3	0.2	0.1	0.1	0.4	0.1	0.3	0.1	0.3	0.0	0.0	0.0	0.0	0.2	0.4	0.1	0.0	0.0	0.0	0.0	0.0	0.5	4.3	0.0	0.0	0.0	0.0	0.0	12.3	1.9	0.1	5.8	0.0	0.0	0.1	1.8	5.3	0.0	0.4	0.1	0.0	0.0	0.0	0.0	0.0	1.4	139.7	0.0	0.0	0.0	8.9	0.0	3.8	0.0	18.4	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	9.3	0.0	0.0	0.5	204.6	37.7	0.0	0.0	0.0	0.0	0.7	0.1	0.4	0.0	0.1	0.0	0.2	0.1	5.6	0.2
CYP4F3	"CYP4F, LTB4H"	ENSG00000186529	"Cytochrome P450 family 4 subfamily F member 3"	Q08477	19	15640897-15662825	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"bone marrow: 80.2;liver: 235.8"	"Cell type enriched"	"Detected in many"	8	"Hepatocytes: 562.4"	"Cancer enhanced"	"Detected in many"		"liver cancer: 30.6"	"Low region specificity"	"Detected in many"			"Immune cell enriched"	"Detected in some"	63	"neutrophil: 84.1"	"Lineage enriched"	"Detected in single"	177	"granulocytes: 84.1"	"Cell line enhanced"	"Detected in some"		"CAPAN-2: 33.0;HaCaT: 14.9;Hep G2: 18.3;OE19: 49.3"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			HPA058960	Approved					NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 60: Liver - Hemostasis & Lipid metabolism"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 2: Hepatocytes - Metabolism"			"HPA058960: AB_2683862"	"unprognostic (1.73e-2)"	"unprognostic (9.70e-3)"	"unprognostic (1.21e-1)"	"unprognostic (1.16e-3)"	"unprognostic (5.40e-1)"	"unprognostic (1.57e-1)"	"unprognostic (7.15e-3)"	"unprognostic (5.19e-2)"	"unprognostic (2.12e-1)"	"unprognostic (3.61e-2)"	"unprognostic (1.26e-2)"	"unprognostic (2.32e-1)"	"unprognostic (1.59e-3)"	"unprognostic (2.36e-1)"	"unprognostic (1.12e-1)"	"unprognostic (1.07e-2)"	"unprognostic (2.07e-1)"	1.6	0.1	0.9	1.2	3.3	80.2	0.2	2.3	1.3	6.9	0.3	2.1	9.4	0.1	0.8	26.7	1.1	15.5	0.3	1.8	2.2	27.3	235.8	2.3	0.1	2.8	3.0	0.0	0.6	0.0	0.5	0.4	2.9	0.6	1.8	0.0	3.4	0.6	0.1	3.9	15.0	0.3	1.9	7.8	5.1	0.3	1.9	0.7	0.1	0.6	0.7	2.9	9.0	4.1	0.3	7.3	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.3	0.0	0.0	33.0	0.1	0.2	0.0	0.1	14.9	0.0	0.2	0.0	0.6	0.0	0.1	3.5	18.3	0.0	0.2	0.1	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.2	0.0	49.3	0.0	0.0	0.1	0.0	0.0	0.8	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.0	1.1	0.0	0.2	0.4	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	84.1	0.0	0.1	0.0	0.0	0.1	0.9	3.3	2.3	1.3	1.8	2.2	2.8	3.0	2.9	1.9	1.9	4.1	0.0	9.6	3.7	0.7	2.0	1.0	2.1	2.5	1.2	0.0	0.1	0.1	0.9	62.9	5.0	0.0	0.0	0.0	1.4	10.0	0.0	2.3	0.1	0.9	0.2	0.7	53.1	17.3	0.0	0.2	0.2	0.8	7.7	3.1	1.3	0.0	8.2	562.4	0.0	0.0	0.0	14.4	8.2	11.4	0.3	0.7	0.0	1.2	0.0	0.0	1.2	0.0	0.0	0.0	0.0	4.0	7.4	0.0	0.0	3.2	69.9	32.1	1.9	0.0	0.0	0.7	1.3	0.0	0.3	25.7	6.5	0.0	1.1	0.0	10.9	13.1
CYP4F8		ENSG00000186526	"Cytochrome P450 family 4 subfamily F member 8"	P98187	19	15615218-15630639	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Fatty acid metabolism, Lipid metabolism"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	15	"seminal vesicle: 215.6"	"Cell type enhanced"	"Detected in some"		"Basal prostatic cells: 1.2;Breast glandular cells: 1.7;granulocytes: 1.3;NK-cells: 1.0;Prostatic glandular cells: 1.3;Skeletal myocytes: 1.7;Urothelial cells: 2.5"	"Cancer enhanced"	"Detected in some"		"urothelial cancer: 10.4"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"SK-BR-3: 1.1"					"Low region specificity"	"Detected in all"			HPA058960	Approved					NA	NA				"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 50: Fibroblasts - ECM organization"			"HPA058960: AB_2683862"	"unprognostic (1.70e-2)"	"unprognostic (5.46e-3)"	"unprognostic (3.21e-2)"	"unprognostic (3.97e-6)"		"unprognostic (3.51e-3)"				"unprognostic (2.72e-1)"	"unprognostic (1.15e-1)"	"unprognostic (8.25e-2)"		"unprognostic (1.15e-2)"			"unprognostic (1.02e-3)"	0.0	0.0	0.0	0.0	0.0	0.0	5.3	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	14.8	0.0	0.0	0.2	215.6	0.0	12.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.9	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	1.2	0.0	0.0	0.4	1.7	0.3	0.7	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.5	0.2	0.1	0.2	0.0	0.0	0.0	0.0	0.1	0.3	0.0	0.3	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.9	0.0	0.3	0.0	0.0	0.1	0.1	1.0	0.0	0.0	0.1	0.0	0.0	0.0	1.3	0.0	0.0	0.0	0.7	0.0	1.7	0.2	0.0	0.2	0.0	0.0	0.1	0.2	0.0	0.3	2.5
CYP4V2	CYP4AH1	ENSG00000145476	"Cytochrome P450 family 4 subfamily V member 2"	Q6ZWL3	4	186191567-186213463	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"Lipid metabolism, Sensory transduction, Vision"	"Monooxygenase, Oxidoreductase"	"Corneal dystrophy, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 113.5"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 103.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"ASC diff: 15.2;SK-MEL-30: 27.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA029122	Approved		Approved	"Nuclear speckles"		NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 85: Liver - Metabolism"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 2: Hepatocytes - Metabolism"	"Nuclear speckles"		"HPA029122: AB_10601806"	"unprognostic (1.65e-1)"	"unprognostic (5.37e-2)"	"unprognostic (2.35e-1)"	"prognostic favorable (5.86e-4)"	"unprognostic (1.45e-1)"	"unprognostic (1.02e-1)"	"prognostic favorable (1.85e-4)"	"unprognostic (6.66e-2)"	"unprognostic (5.84e-2)"	"unprognostic (2.05e-1)"	"unprognostic (6.49e-2)"	"unprognostic (9.89e-2)"	"prognostic favorable (1.49e-7)"	"unprognostic (3.25e-2)"	"unprognostic (8.96e-2)"	"unprognostic (1.02e-1)"	"unprognostic (3.14e-2)"	7.4	16.4	5.1	5.2	6.8	2.1	5.7	5.6	5.0	8.6	17.9	9.6	16.5	5.6	2.6	5.0	6.1	14.7	9.2	4.8	5.1	33.9	113.5	10.8	5.6	5.3	6.0	5.7	15.6	33.4	3.7	3.5	5.3	8.2	11.9	14.2	7.0	7.5	4.5	1.3	16.7	7.1	5.4	11.2	6.2	3.2	5.6	6.5	17.3	5.0	4.9	6.4	2.3	6.3	3.4	1.8	0.8	0.0	15.2	6.3	0.2	4.4	9.9	1.7	1.9	0.0	13.0	1.1	0.5	3.5	5.9	1.6	1.9	1.7	0.3	6.0	2.2	4.7	0.8	0.5	5.6	2.6	1.9	5.8	0.8	1.9	1.0	5.9	0.1	6.4	1.4	14.3	6.8	2.9	3.6	1.3	1.5	1.6	0.0	3.1	0.7	1.0	7.4	6.1	4.0	4.9	1.1	0.0	27.5	0.3	2.6	4.6	4.1	3.6	0.7	3.5	1.6	0.1	0.0	0.5	10.9	11.0	4.7	0.0	0.6	0.0	1.8	1.9	1.0	0.4	1.4	1.8	0.7	1.0	1.3	1.3	0.0	0.8	3.1	1.3	1.1	0.9	5.1	6.8	5.6	5.0	4.8	5.1	5.3	6.0	5.3	5.4	5.6	6.3	9.0	6.4	11.5	31.3	13.8	2.5	4.5	5.1	9.6	33.6	9.3	7.2	18.8	42.9	8.7	14.7	31.3	2.0	9.6	14.7	9.8	24.2	2.7	6.7	5.1	7.7	16.9	16.4	15.4	22.4	2.1	14.2	12.8	7.6	7.0	6.5	8.9	103.7	13.5	5.0	23.4	16.5	2.0	14.8	6.0	2.1	5.0	11.3	3.6	6.5	3.5	52.2	4.1	15.6	11.0	9.6	9.0	6.4	12.3	3.8	47.2	28.5	11.9	27.4	0.0	10.1	10.6	8.9	6.3	6.8	3.1	1.0	17.2	6.7	10.5	5.7
CYP4Z1	CYP4A20	ENSG00000186160	"Cytochrome P450 family 4 subfamily Z member 1"	Q86W10	1	47067231-47118318	"Enzymes, Metabolic proteins, Predicted membrane proteins"	"Fatty acid metabolism, Lipid metabolism"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"breast: 6.3"	"Cell type enhanced"	"Detected in some"		"Alveolar cells type 1: 9.6;Breast glandular cells: 8.3;Early spermatids: 2.5;Excitatory neurons: 8.3;Inhibitory neurons: 5.8"	"Cancer enriched"	"Detected in some"	50	"breast cancer: 42.3"	"Low region specificity"	"Detected in some"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	33	"HDLM-2: 8.1;SK-BR-3: 3.2"															NA	NA				"Cluster 82: Adipose tissue - ECM organization"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"				"unprognostic (4.11e-2)"	"unprognostic (2.57e-2)"	"unprognostic (2.46e-1)"	"unprognostic (5.12e-2)"	"unprognostic (1.37e-1)"	"unprognostic (4.33e-4)"	"unprognostic (1.10e-1)"	"unprognostic (3.53e-3)"		"unprognostic (7.76e-3)"	"unprognostic (1.21e-1)"	"unprognostic (3.53e-1)"	"unprognostic (6.82e-3)"	"unprognostic (5.09e-3)"	"unprognostic (3.88e-2)"	"unprognostic (6.46e-2)"	"unprognostic (3.49e-3)"	2.2	0.2	0.9	0.0	0.9	0.0	6.3	0.2	1.1	0.3	0.0	0.2	0.0	0.3	0.3	0.7	0.6	0.0	0.8	0.8	1.3	0.2	0.7	1.6	0.0	0.4	0.4	0.0	0.1	0.0	0.6	0.0	0.3	1.2	0.0	0.0	0.8	0.3	0.7	1.0	0.2	0.0	0.2	0.0	0.4	0.4	1.1	0.2	0.5	0.2	0.2	0.4	0.4	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	8.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	3.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.9	0.2	1.1	0.8	1.3	0.4	0.4	0.3	0.2	1.1	0.9	0.3	9.6	1.1	1.0	0.0	0.1	0.5	0.4	0.0	0.0	8.3	0.4	0.4	0.0	1.8	0.0	0.0	0.0	0.1	0.1	0.0	0.0	2.5	0.2	0.1	0.9	0.0	0.0	8.3	0.0	0.0	0.7	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	5.8	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.2	0.0	0.0	1.2	0.0	0.0	0.1	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.7
CYP51A1	"CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1"	ENSG00000001630	"Cytochrome P450 family 51 subfamily A member 1"	Q16850	7	92112153-92134803	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	"Monooxygenase, Oxidoreductase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 204.7"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 67.3;Alveolar cells type 2: 169.7;Early spermatids: 74.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"GAMG: 481.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041325, HPA043508"	Enhanced		Enhanced	"Endoplasmic reticulum"		NA	NA			"Cluster 23: Antigen presenting cells - Antigen presentation"	"Cluster 37: Intestine - Unknown function"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 11: Alveolar cells - Smell perception"	"Endoplasmic reticulum"		"HPA041325: AB_2677411, HPA043508: AB_2678520"	"unprognostic (6.68e-2)"	"prognostic unfavorable (6.12e-4)"	"unprognostic (3.48e-2)"	"unprognostic (1.18e-2)"	"unprognostic (7.82e-2)"	"unprognostic (3.60e-2)"	"unprognostic (1.02e-1)"	"unprognostic (1.97e-1)"	"unprognostic (9.84e-2)"	"unprognostic (1.36e-1)"	"unprognostic (9.75e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.59e-9)"	"unprognostic (1.82e-1)"	"unprognostic (2.73e-1)"	"unprognostic (5.13e-2)"	"unprognostic (1.09e-3)"	19.4	58.2	22.3	20.6	24.9	30.3	30.6	39.8	32.3	26.4	21.0	52.7	86.6	21.2	35.8	43.7	16.7	24.3	20.7	24.2	39.0	38.7	204.7	53.2	13.1	60.1	42.3	29.0	48.7	59.6	17.1	21.9	50.6	43.8	41.5	31.4	20.3	17.5	7.9	26.5	40.0	20.4	46.6	13.4	45.1	86.4	31.8	6.6	33.6	11.7	16.6	21.3	26.2	57.0	113.7	54.3	134.0	86.4	92.0	149.6	18.7	37.7	112.7	47.1	128.8	131.8	201.7	98.1	57.9	65.3	481.6	96.2	118.1	237.0	55.3	40.3	82.6	27.9	51.1	99.7	125.7	56.0	39.4	109.1	105.7	185.6	194.0	42.2	49.4	19.8	108.2	217.8	56.4	115.6	12.5	53.8	100.7	45.9	53.4	40.3	27.8	222.8	216.7	187.9	94.1	62.5	80.0	156.3	117.2	60.6	56.9	69.5	59.5	65.0	70.6	95.2	49.8	72.8	70.5	88.1	49.8	75.5	85.2	2.8	11.1	3.9	11.6	16.3	7.7	15.6	8.0	8.9	16.3	12.3	7.1	9.6	1.5	7.8	10.3	14.3	6.7	8.2	22.3	24.9	39.8	32.3	24.2	39.0	60.1	42.3	50.6	46.6	31.8	57.0	3.1	67.3	169.7	35.9	24.0	2.5	1.6	4.6	48.9	2.6	6.7	3.7	1.6	7.2	44.5	1.8	2.1	1.5	8.9	20.3	1.9	10.7	74.4	10.7	8.1	7.7	10.8	11.6	34.3	19.8	1.0	9.1	43.3	16.4	28.5	4.1	5.3	45.2	1.5	0.0	39.6	13.1	2.0	5.6	1.9	34.4	3.7	9.2	0.0	15.9	1.3	2.4	0.0	39.2	53.1	14.2	11.7	1.5	34.3	1.4	9.6	1.5	15.7	1.9	0.0	4.0	6.5	7.8	4.2	51.4	5.4	4.4	12.2	9.3	11.9	2.5
CYP7A1	CYP7	ENSG00000167910	"Cytochrome P450 family 7 subfamily A member 1"	P22680	8	58490178-58500163	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	80	"liver: 49.5"	"Cell type enriched"	"Detected in single"	17	"Hepatocytes: 7.0"	"Cancer enriched"	"Detected in single"	96	"liver cancer: 28.4"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"									NA	NA				"Cluster 60: Liver - Hemostasis & Lipid metabolism"		"Cluster 2: Hepatocytes - Metabolism"				"unprognostic (5.20e-2)"			"unprognostic (1.93e-2)"	"unprognostic (1.77e-2)"		"prognostic favorable (3.19e-4)"	"unprognostic (7.60e-2)"	"unprognostic (5.31e-2)"	"unprognostic (1.50e-1)"	"unprognostic (1.18e-1)"	"unprognostic (2.64e-1)"	"unprognostic (8.43e-3)"	"unprognostic (3.01e-1)"	"unprognostic (1.57e-2)"	"unprognostic (1.51e-1)"		0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.6	0.0	0.0	0.0	0.4	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	49.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.6	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	7.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0
CYP7B1	SPG5A	ENSG00000172817	"Cytochrome P450 family 7 subfamily B member 1"	O75881	8	64587763-64798737	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism"	"Monooxygenase, Oxidoreductase"	"Disease variant, Hereditary spastic paraplegia, Intrahepatic cholestasis, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 27.2"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 93.7;Oligodendrocyte precursor cells: 94.5;Oligodendrocytes: 119.2"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	11	"basophil: 2.5;eosinophil: 1.5"	"Lineage enriched"	"Detected in single"	25	"granulocytes: 2.5"	"Group enriched"	"Detected in some"	4	"HSkMC: 16.5;SH-SY5Y: 5.5;WM-115: 10.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA017761	Uncertain					NA	NA			"Cluster 2: Granulocytes - Unknown function"	"Cluster 73: Brain - Neuropeptide signaling"	"Cluster 17: WM-115 - Nervous system development"	"Cluster 68: Oligodendrocytes - Mixed function"			"HPA017761: AB_1847455"	"unprognostic (3.19e-2)"	"unprognostic (1.91e-1)"	"unprognostic (1.50e-1)"	"unprognostic (6.89e-3)"	"unprognostic (1.07e-1)"	"unprognostic (5.80e-3)"	"unprognostic (3.80e-1)"	"unprognostic (5.50e-2)"	"unprognostic (6.11e-3)"	"unprognostic (2.46e-1)"	"unprognostic (1.61e-1)"	"unprognostic (3.19e-2)"	"unprognostic (1.87e-2)"	"unprognostic (2.38e-3)"	"unprognostic (4.00e-1)"	"unprognostic (3.04e-3)"	"unprognostic (6.75e-3)"	8.4	5.4	5.7	5.6	11.4	0.3	6.3	8.2	6.6	5.7	8.6	2.3	1.8	2.8	2.0	7.3	2.7	5.8	3.6	5.3	6.8	7.9	21.5	4.6	2.4	11.8	7.3	4.2	6.7	11.4	0.8	0.5	11.4	4.4	3.5	1.9	4.6	5.6	0.2	5.9	1.8	4.3	8.4	9.2	2.4	1.7	8.1	2.1	12.2	1.7	2.9	7.9	3.0	27.2	1.5	0.6	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.1	0.0	0.2	0.2	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.4	0.0	0.0	16.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.6	0.0	0.0	0.0	0.0	0.0	0.5	0.0	1.6	5.5	0.0	0.0	2.2	0.8	0.0	1.4	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	10.3	2.5	0.0	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	5.7	11.4	8.2	6.6	5.3	6.8	11.8	7.3	11.4	8.4	8.1	27.2	3.3	0.0	3.4	93.7	0.1	10.6	6.6	1.0	7.4	4.9	4.2	5.5	3.0	2.8	0.9	7.3	2.1	0.1	0.4	0.0	3.9	4.4	7.4	0.2	6.9	2.1	1.8	1.3	29.3	4.9	0.2	15.9	0.5	0.1	12.7	0.6	2.5	8.2	0.2	3.3	30.6	0.5	0.0	0.3	4.9	8.6	5.9	0.5	17.8	30.0	1.0	6.9	0.0	94.5	119.2	1.2	0.0	4.9	0.0	4.2	0.0	2.9	0.8	0.5	13.1	1.1	16.8	4.1	3.4	6.2	12.6	0.0	1.3	7.6	0.0	3.1
CYP8B1	CYP12	ENSG00000180432	"Cytochrome P450 family 8 subfamily B member 1"	Q9UNU6	3	42856005-42875898	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	28	"liver: 404.5"	"Cell type enriched"	"Detected in some"	76	"Hepatocytes: 920.2"	"Cancer enriched"	"Detected in some"	46	"liver cancer: 69.6"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"BEWO: 2.4;SK-BR-3: 1.1"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"									NA	NA				"Cluster 62: Liver - Hemostasis"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 2: Hepatocytes - Metabolism"				"unprognostic (1.58e-2)"	"unprognostic (5.41e-2)"	"unprognostic (6.38e-2)"	"unprognostic (1.15e-2)"	"unprognostic (8.95e-2)"	"unprognostic (1.42e-3)"	"unprognostic (4.47e-3)"	"unprognostic (1.49e-1)"	"unprognostic (9.85e-2)"	"unprognostic (4.04e-3)"	"unprognostic (5.86e-3)"	"unprognostic (2.74e-1)"	"unprognostic (3.37e-1)"	"unprognostic (1.03e-1)"	"unprognostic (3.63e-1)"	"unprognostic (3.19e-1)"	"unprognostic (1.24e-1)"	0.3	0.1	0.2	0.1	0.1	0.0	0.1	0.1	0.1	0.1	0.1	0.1	0.0	0.0	0.9	0.2	0.1	0.5	0.1	0.2	0.1	14.4	404.5	0.2	0.0	0.1	0.1	0.0	0.1	0.0	0.1	0.4	0.1	0.0	0.0	0.1	0.1	0.1	0.1	0.4	0.1	0.0	0.0	0.2	0.1	0.1	0.2	0.0	0.3	0.0	0.0	0.1	0.1	0.1	0.1	0.2	0.1	0.0	0.0	0.0	2.4	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.1	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.9	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.1	0.1	0.0	0.1	0.0	0.1	0.2	0.2	0.1	0.1	0.1	0.0	0.0	0.2	1.1	0.1	0.1	0.1	0.0	0.1	0.1	0.2	0.1	0.1	0.1	0.0	0.0	0.1	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.1	0.1	0.2	0.1	0.1	0.1	0.1	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	8.6	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.4	0.0	5.3	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	7.9	920.2	0.1	0.0	0.0	0.0	0.0	10.7	0.0	0.8	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	12.1	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.4	0.4	0.0	0.0	0.0
DAO	"DAAO, DAMOX"	ENSG00000110887	"D-amino acid oxidase"	P14920	12	108858932-108901043	"Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	Schizophrenia	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	9	"brain: 71.4;kidney: 90.3;liver: 149.9"	"Group enriched"	"Detected in some"	8	"Hepatocytes: 46.1;Proximal tubular cells: 86.8"	"Cancer enriched"	"Detected in some"	9	"liver cancer: 13.2"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"Hep G2: 1.1"	"Group enriched"	"Detected in some"	10	"cerebellum: 66.4;pons and medulla: 20.2"	"Low region specificity"	"Detected in all"			"HPA038653, HPA038654"	Enhanced				"Intracellular and membrane"	NA	NA				"Cluster 15: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA038653: AB_10673016, HPA038654: AB_10673285"	"unprognostic (1.50e-1)"	"unprognostic (5.61e-2)"	"unprognostic (1.43e-1)"	"unprognostic (2.91e-1)"	"unprognostic (2.18e-1)"	"unprognostic (2.99e-2)"	"unprognostic (2.31e-3)"	"unprognostic (8.02e-2)"	"unprognostic (2.88e-2)"	"unprognostic (9.59e-2)"	"unprognostic (9.07e-2)"	"unprognostic (7.13e-2)"	"prognostic favorable (4.11e-4)"	"unprognostic (3.44e-3)"	"unprognostic (8.96e-2)"	"unprognostic (2.67e-1)"	"unprognostic (2.17e-1)"	0.1	0.0	0.9	0.0	6.9	0.0	0.0	71.4	1.6	0.0	0.5	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	3.3	90.3	149.9	0.2	0.0	41.9	14.8	0.0	0.2	0.0	0.0	0.0	29.5	0.0	2.0	12.0	0.0	0.0	0.0	0.0	0.0	0.1	44.0	0.1	0.1	0.1	4.3	0.0	0.0	0.0	0.0	0.0	0.0	59.1	0.0	0.0	0.3	0.0	0.0	0.3	0.3	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.4	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	6.9	71.4	1.6	0.8	3.3	41.9	14.8	29.5	44.0	4.3	59.1	0.0	0.0	0.0	0.3	1.6	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.5	0.0	0.0	1.8	0.0	0.7	0.0	4.6	3.9	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.4	46.1	0.2	0.0	1.2	0.0	0.0	0.8	0.0	0.1	0.0	0.4	0.0	0.0	0.0	1.7	0.0	0.5	0.1	0.0	1.2	0.0	0.0	0.0	0.0	86.8	0.0	7.9	0.0	0.0	0.0	0.0	0.1	0.0	0.0	4.7	0.4	0.0	0.2	0.0
DBH	DBM	ENSG00000123454	"Dopamine beta-hydroxylase"	P09172	9	133636363-133659329	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Catecholamine biosynthesis"	"Monooxygenase, Oxidoreductase"	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	7	"adrenal gland: 272.7;brain: 236.6"	"Cell type enriched"	"Detected in some"	6	"Hepatic stellate cells: 10.0"	"Cancer enhanced"	"Detected in some"		"liver cancer: 1.7"	"Region enriched"	"Detected in many"	8	"pons: 236.6"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	346	"SH-SY5Y: 1826.4"	"Region enriched"	"Detected in some"	6	"pons and medulla: 22.1"	"Region enriched"	"Detected in single"	26	"pons: 18.5"	"HPA002130, HPA005960, HPA070789"	Enhanced		Supported	"Endoplasmic reticulum,Vesicles"	"Intracellular and membrane"	NA	NA		1600000000	"Cluster 32: T-cells - Unknown function"	"Cluster 26: Pituitary gland - Hormone signaling"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 43: Cardiomyocytes - Nuclear processes"	Vesicles	"Endoplasmic reticulum"	"HPA002130: AB_2666554, HPA005960: AB_1078628, HPA070789: AB_2686312"	"unprognostic (1.93e-3)"	"unprognostic (7.52e-3)"	"unprognostic (8.53e-2)"	"unprognostic (2.10e-2)"	"unprognostic (2.18e-3)"	"unprognostic (3.38e-3)"	"unprognostic (3.39e-3)"	"unprognostic (3.97e-2)"	"unprognostic (1.71e-1)"	"unprognostic (8.99e-2)"	"unprognostic (5.80e-2)"	"unprognostic (7.69e-2)"	"unprognostic (2.81e-7)"	"unprognostic (9.31e-2)"	"unprognostic (6.77e-2)"	"unprognostic (1.49e-2)"	"unprognostic (5.06e-3)"	2.8	272.7	0.1	1.0	0.2	0.2	0.1	0.0	0.8	0.4	0.0	0.1	0.4	0.3	0.2	0.1	0.3	0.3	0.5	0.3	0.2	1.3	36.1	0.8	2.3	9.8	29.4	0.4	4.3	0.0	1.4	1.4	236.6	0.4	0.0	0.1	0.6	0.2	0.1	0.2	0.6	0.0	0.0	0.9	0.4	0.2	0.6	0.2	0.4	0.0	0.0	0.4	1.1	1.0	0.0	0.0	0.1	0.9	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.3	0.0	0.0	0.0	0.2	3.2	0.9	0.1	0.0	0.0	0.3	5.2	4.7	0.0	0.0	2.1	1826.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.4	0.2	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.8	0.3	0.2	9.8	29.4	236.6	0.0	0.6	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2	0.0	0.0	0.2	0.0	0.0	0.0	0.0	10.0	0.1	0.0	0.0	0.1	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.1	1.0	0.0	0.0
DCXR	"DCR, HCR2, KIDCR, P34H, SDR20C1"	ENSG00000169738	"Dicarbonyl and L-xylulose reductase"	Q7Z4W1	17	82035136-82037709	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Carbohydrate metabolism, Glucose metabolism, Xylose metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	7	"liver: 1851.6"	"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 812.0;Hepatocytes: 3510.3;Proximal tubular cells: 2919.4"	"Group enriched"	"Detected in all"	5	"liver cancer: 305.9;prostate cancer: 163.4"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"Hep G2: 365.2;MCF7: 446.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA023371, HPA023863"	Enhanced		Uncertain	Nucleoli,Microtubules		NA	NA		4000000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 85: Liver - Metabolism"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	"Nucleoli, Microtubules"		"HPA023371: AB_1847530, HPA023863: AB_1847531"	"unprognostic (3.33e-2)"	"unprognostic (1.67e-3)"	"unprognostic (3.75e-1)"	"unprognostic (1.16e-2)"	"unprognostic (1.19e-1)"	"unprognostic (8.43e-2)"	"unprognostic (4.54e-3)"	"unprognostic (1.86e-2)"	"unprognostic (3.05e-1)"	"unprognostic (2.56e-2)"	"prognostic favorable (4.70e-4)"	"unprognostic (1.72e-1)"	"prognostic favorable (2.13e-4)"	"unprognostic (1.81e-1)"	"unprognostic (1.36e-1)"	"unprognostic (2.64e-1)"	"unprognostic (1.10e-2)"	106.7	43.9	93.1	15.2	95.3	25.3	107.6	102.5	111.1	52.0	84.4	49.6	29.2	39.5	281.3	96.6	59.2	10.8	132.7	87.6	100.7	239.9	1851.6	61.0	16.6	102.4	98.0	70.0	71.6	46.1	63.9	20.2	105.9	138.0	20.9	9.7	103.4	33.6	187.3	87.6	44.4	10.4	91.8	35.8	167.0	44.8	105.9	26.1	60.7	80.6	19.6	48.9	62.1	94.9	50.3	68.2	32.8	56.4	123.2	31.8	80.4	25.0	33.9	68.5	48.4	122.0	21.3	100.3	47.4	35.9	9.4	57.4	59.6	52.6	24.1	21.4	145.9	96.9	48.8	365.2	143.2	75.6	114.5	44.6	62.2	22.7	79.8	16.0	41.1	61.1	112.4	76.3	36.5	446.2	63.7	184.1	35.0	242.9	71.3	57.9	42.0	135.3	53.3	71.9	85.5	51.0	35.5	287.5	46.0	19.7	213.4	74.5	20.5	36.6	45.0	48.9	48.2	73.7	56.2	50.2	31.4	83.0	26.7	49.5	92.6	77.9	66.5	92.0	64.1	86.8	83.0	64.7	151.3	99.2	117.7	85.4	47.2	108.9	88.1	121.6	98.9	110.1	93.1	95.3	102.5	111.1	87.6	100.7	102.4	98.0	105.9	91.8	105.9	94.9	29.0	51.3	198.2	16.6	133.6	58.5	200.3	113.5	109.8	16.0	301.8	269.2	120.7	183.0	123.4	178.4	18.8	372.1	116.6	152.9	812.0	41.4	6.0	67.0	50.9	44.6	54.7	335.7	4.7	42.6	450.6	65.0	151.4	102.3	64.7	62.7	138.5	3510.3	164.7	21.9	9.0	170.4	189.2	165.7	65.6	22.6	70.8	82.3	179.7	1.9	52.8	145.1	78.2	5.5	10.5	30.4	135.7	47.4	98.6	215.2	158.9	2919.4	55.4	26.5	19.7	40.6	79.6	10.3	48.2	219.9	73.2	342.6	135.7	118.6	154.6	178.8
DDO		ENSG00000203797	"D-aspartate oxidase"	Q99489	6	110391771-110415575	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 18.4"	"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 17.4;Muller glia cells: 8.2;Oligodendrocytes: 13.3;Paneth cells: 8.5;Proximal enterocytes: 8.5;Proximal tubular cells: 12.9"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"intermediate monocyte: 3.3;myeloid DC: 4.7"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in some"		"GAMG: 11.5;RPMI-8226: 15.9;U-937: 17.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA037525, HPA037526"	Enhanced		Enhanced	Cytosol		NA	NA			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 54: Cardiomyocytes - Muscle contraction"	Cytosol		"HPA037525: AB_2675523, HPA037526: AB_10672352"	"unprognostic (1.37e-1)"	"unprognostic (1.54e-1)"	"unprognostic (6.51e-2)"	"unprognostic (1.30e-2)"	"unprognostic (2.00e-1)"	"unprognostic (3.28e-2)"	"unprognostic (3.71e-2)"	"unprognostic (1.01e-2)"	"unprognostic (2.05e-1)"	"unprognostic (2.91e-1)"	"unprognostic (6.97e-2)"	"unprognostic (1.43e-1)"	"prognostic favorable (8.69e-5)"	"unprognostic (3.51e-4)"	"unprognostic (3.36e-3)"	"unprognostic (1.27e-3)"	"unprognostic (9.06e-2)"	1.9	8.2	4.5	0.8	7.0	1.4	2.5	5.0	4.8	1.9	4.3	2.3	7.4	2.1	2.7	0.8	4.9	2.9	18.4	4.4	4.5	10.6	11.1	3.2	1.0	5.4	4.9	0.3	2.6	5.3	1.2	1.6	5.3	2.0	3.2	2.4	4.2	2.3	10.9	0.4	7.0	2.2	4.8	2.1	1.1	0.1	4.7	0.4	1.3	7.4	0.2	1.6	0.9	5.9	0.2	0.0	0.0	0.1	0.0	0.2	1.1	0.1	5.4	1.3	0.9	0.0	0.1	0.0	0.7	0.7	11.5	0.0	0.0	0.0	2.3	5.0	0.0	5.1	0.1	4.3	1.6	0.0	0.0	0.1	0.0	2.7	0.1	2.3	0.0	0.0	0.0	1.9	4.5	0.0	0.0	0.2	0.0	0.0	0.1	0.1	3.0	15.9	0.0	4.9	0.1	0.2	0.0	0.5	0.6	0.0	0.7	1.1	0.9	1.0	0.1	0.0	2.6	0.1	0.4	0.0	2.0	17.4	0.0	0.0	2.9	0.0	0.0	3.3	0.0	0.0	0.0	0.0	4.7	0.0	0.0	0.0	0.0	1.1	1.0	0.0	0.0	1.1	4.5	7.0	5.0	4.8	4.4	4.5	5.4	4.9	5.3	4.8	4.7	5.9	1.1	0.0	0.0	4.9	0.0	0.0	0.7	0.7	0.6	0.0	1.4	1.1	17.4	0.0	0.4	0.0	2.1	0.2	0.1	1.8	3.9	4.5	0.3	3.6	0.5	0.7	4.2	0.0	0.0	2.2	0.2	0.6	0.0	0.9	0.0	0.1	2.5	4.9	1.7	0.0	0.1	6.0	0.0	3.1	0.4	0.0	0.3	1.6	0.0	0.0	2.0	8.2	0.0	3.5	13.3	0.8	8.5	0.0	0.0	0.4	8.5	12.9	2.2	0.2	0.0	2.1	1.2	0.0	0.0	0.2	0.0	0.0	0.2	0.3	5.0	0.5
DECR1	"DECR, SDR18C1"	ENSG00000104325	"2,4-dienoyl-CoA reductase 1"	Q16698	8	90001405-90053633	"Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 290.1;liver: 272.3"	"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 399.2;Proximal tubular cells: 485.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-BR-3: 81.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA023160, HPA023162, HPA023238"	Enhanced		Supported	Mitochondria,Cytosol		No	No		120000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria	Cytosol	"HPA023160: AB_1847585, HPA023162: AB_1847586, HPA023238: AB_1847587"	"prognostic unfavorable (1.49e-4)"	"unprognostic (5.76e-3)"	"unprognostic (8.37e-3)"	"unprognostic (6.13e-3)"	"unprognostic (2.01e-1)"	"unprognostic (4.45e-2)"	"unprognostic (1.68e-2)"	"unprognostic (8.23e-2)"	"unprognostic (1.02e-1)"	"unprognostic (1.55e-1)"	"unprognostic (9.12e-2)"	"unprognostic (1.42e-1)"	"prognostic favorable (1.79e-7)"	"unprognostic (1.40e-1)"	"unprognostic (1.73e-2)"	"unprognostic (1.16e-1)"	"prognostic favorable (6.06e-4)"	60.2	136.8	12.4	9.6	14.4	24.9	54.4	12.5	14.4	29.4	22.2	65.0	20.2	28.0	14.9	52.6	26.1	7.4	290.1	12.7	13.2	103.5	272.3	34.2	15.0	12.2	13.1	35.5	44.4	13.2	32.6	5.9	12.1	28.6	18.8	8.0	42.8	6.5	121.8	43.3	61.0	9.1	12.5	47.1	44.5	52.3	15.4	10.2	33.0	34.4	13.9	31.1	35.8	12.8	13.1	7.9	19.6	16.1	8.0	17.3	5.2	13.2	12.9	5.9	8.2	2.8	13.4	7.7	5.3	15.1	4.1	6.8	7.7	11.1	11.0	12.6	1.2	18.4	13.6	14.5	11.6	8.7	4.4	12.0	7.0	7.6	10.7	10.1	17.4	16.5	21.3	15.5	20.7	16.3	12.5	7.6	1.5	9.1	24.9	7.4	5.8	13.4	23.4	43.9	1.3	10.6	13.0	81.1	7.7	1.1	10.7	7.4	20.1	11.4	6.2	12.9	6.0	10.5	7.5	12.8	8.6	12.0	10.8	3.9	9.1	6.2	7.1	10.2	7.9	7.4	6.9	8.6	8.8	4.6	8.1	7.8	15.2	3.9	9.3	3.9	9.6	5.8	12.4	14.4	12.5	14.4	12.7	13.2	12.2	13.1	12.1	12.5	15.4	12.8	66.1	76.9	59.4	72.5	52.9	41.3	70.6	180.2	35.3	11.4	51.1	57.4	268.3	82.9	96.4	71.7	2.1	50.2	57.6	119.0	399.2	137.8	165.3	68.2	65.5	60.0	104.8	77.4	27.2	92.5	49.0	60.2	61.2	40.6	50.0	81.3	47.8	244.8	115.1	32.0	55.9	105.9	116.0	95.2	82.7	52.6	85.4	85.1	85.4	29.0	107.1	52.5	74.2	66.9	35.0	87.5	111.6	51.6	67.8	30.3	250.3	485.2	69.0	7.6	72.3	54.5	61.7	157.5	24.6	68.6	41.1	41.0	64.4	135.1	139.6	86.8
DECR2	"PDCR, SDR17C1"	ENSG00000242612	"2,4-dienoyl-CoA reductase 2"	Q9NUI1	16	401858-412487	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"liver: 165.1"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 129.2;Proximal enterocytes: 81.3;Proximal tubular cells: 159.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in all"		"Hep G2: 37.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA047631			Approved	Peroxisomes,Microtubules		NA	NA			"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Peroxisomes	Microtubules	"HPA047631: "	"unprognostic (2.74e-2)"	"unprognostic (3.84e-1)"	"unprognostic (1.83e-1)"	"unprognostic (4.44e-3)"	"unprognostic (1.77e-1)"	"unprognostic (7.45e-2)"	"unprognostic (2.38e-2)"	"unprognostic (1.17e-1)"	"unprognostic (1.91e-1)"	"unprognostic (3.02e-2)"	"unprognostic (3.11e-2)"	"unprognostic (3.38e-1)"	"unprognostic (1.12e-1)"	"unprognostic (3.40e-1)"	"unprognostic (2.21e-1)"	"unprognostic (1.94e-1)"	"unprognostic (4.22e-3)"	13.0	34.8	5.5	1.6	5.7	5.8	11.8	5.5	8.1	9.6	5.4	18.5	20.6	10.0	2.0	12.0	9.2	2.1	12.4	6.0	6.6	35.8	165.1	6.8	1.2	5.6	5.5	8.6	21.2	1.7	8.4	2.4	5.5	11.9	2.8	0.5	9.5	7.1	32.3	10.5	17.4	1.5	5.5	6.8	13.8	11.4	6.1	1.8	6.3	7.2	1.0	10.7	8.1	6.1	2.4	22.5	3.4	14.7	4.1	6.3	7.7	7.0	5.7	6.0	6.7	16.2	16.2	6.1	12.2	7.5	3.7	3.5	2.1	6.4	1.3	12.4	5.7	2.3	10.3	37.6	17.7	4.9	11.1	9.1	4.8	4.2	5.5	6.1	6.9	9.5	4.3	7.9	5.5	27.7	3.2	10.2	8.0	9.0	7.5	5.8	1.3	12.2	6.9	6.3	4.3	8.5	11.3	15.9	8.8	1.3	21.9	10.1	10.8	5.1	5.8	7.5	5.6	6.7	7.1	2.6	7.0	10.2	16.1	0.0	3.8	0.1	2.7	5.1	1.5	1.8	1.1	1.5	5.1	1.7	2.6	1.5	0.2	2.9	2.5	7.8	0.9	2.6	5.5	5.7	5.5	8.1	6.0	6.6	5.6	5.5	5.5	5.5	6.1	6.1	9.6	12.8	16.2	5.2	4.3	3.8	7.3	5.6	10.2	2.0	14.9	15.6	8.3	20.0	7.4	20.2	0.0	34.3	5.7	53.8	39.2	37.3	2.6	7.1	8.1	9.4	12.5	29.5	2.3	38.9	7.1	9.9	38.7	9.6	12.7	15.8	7.5	129.2	12.9	3.3	2.7	30.6	6.1	7.3	5.7	6.3	6.5	6.0	5.4	0.0	10.0	7.0	5.2	3.0	2.8	25.3	37.2	6.8	3.8	6.4	81.3	159.1	7.7	3.0	0.0	7.7	8.3	3.8	6.3	12.6	6.0	12.6	3.5	25.8	38.8	5.1
DEGS1	"DEGS-1, Des-1, DES1, FADS7, MLD"	ENSG00000143753	"Delta 4-desaturase, sphingolipid 1"	O15121	1	224175756-224193441	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	Oxidoreductase	"Disease variant, Leukodystrophy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	4	"skin 1: 535.6"	"Cell type enhanced"	"Detected in all"		"Basal keratinocytes: 246.0;Cytotrophoblasts: 281.8;Suprabasal keratinocytes: 320.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"							"Low region specificity"	"Detected in all"			HPA076422			Supported	Mitochondria		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 61: Skin - Cornification"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 47: Cytotrophoblasts - Unknown function"	Mitochondria		"HPA076422: AB_2686799"	"unprognostic (2.34e-2)"	"unprognostic (6.91e-2)"	"unprognostic (2.48e-2)"	"prognostic unfavorable (7.74e-5)"	"unprognostic (1.50e-1)"	"unprognostic (2.74e-1)"	"prognostic unfavorable (4.29e-5)"	"unprognostic (7.70e-2)"	"unprognostic (2.31e-1)"	"unprognostic (3.20e-1)"	"unprognostic (3.63e-1)"	"unprognostic (1.27e-1)"	"prognostic unfavorable (6.83e-7)"	"unprognostic (2.87e-1)"	"unprognostic (1.61e-1)"	"unprognostic (3.86e-2)"	"prognostic unfavorable (2.53e-4)"	60.3	31.0	30.3	44.9	33.1	69.5	61.9	35.0	36.2	53.4	42.5	50.8	47.0	44.5	29.5	48.6	34.4	40.5	43.8	31.3	35.6	38.1	35.7	49.1	48.0	36.6	35.2	27.1	22.5	31.5	34.8	128.7	35.9	83.2	27.2	20.8	38.7	58.6	20.9	535.6	33.4	70.9	37.9	38.7	38.6	22.7	34.0	34.2	52.3	23.3	50.9	48.4	72.7	44.5	72.8	50.7	65.2	49.5	275.7	181.1	51.2	201.1	223.8	137.5	164.2	47.1	55.2	58.0	252.4	181.0	82.4	76.3	76.5	67.9	153.0	84.2	141.5	41.7	51.1	29.2	167.9	84.2	86.1	177.4	153.6	125.5	69.9	143.0	140.4	31.4	62.8	61.8	181.2	27.5	43.2	46.9	83.3	40.0	76.1	38.8	92.4	37.5	181.1	19.8	42.3	69.8	106.6	169.4	110.4	118.8	57.1	123.4	125.7	133.4	41.4	153.1	197.5	44.5	55.3	52.8	141.9	41.7	154.2	104.6	61.4	120.3	30.9	67.8	59.8	58.2	52.7	43.3	104.4	74.3	40.7	37.0	67.7	43.9	48.7	34.9	59.0	52.8	30.3	33.1	35.0	36.2	31.3	35.6	36.6	35.2	35.9	37.9	34.0	44.5	71.7	83.3	29.3	13.4	69.9	246.0	44.0	33.6	89.4	31.2	40.7	38.4	20.8	10.0	19.8	11.0	14.6	281.8	40.5	4.0	13.7	34.9	27.9	54.0	90.2	66.7	14.9	18.7	17.4	43.3	48.3	77.7	21.4	146.1	106.5	21.3	55.6	20.8	93.0	18.5	20.4	6.2	34.6	57.8	90.5	13.6	63.0	72.8	69.4	20.6	57.1	26.0	10.3	25.6	32.1	29.5	5.9	79.4	50.1	44.2	20.1	29.7	20.1	18.4	105.2	42.7	89.1	84.3	44.0	50.4	320.4	198.9	58.9	43.7	6.6	13.7
DEGS2	"C14orf66, DES2, FADS8"	ENSG00000168350	"Delta 4-desaturase, sphingolipid 2"	Q6QHC5	14	100143957-100159645	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 37.0;intestine: 34.8;skin 1: 54.2"	"Cell type enhanced"	"Detected in many"		"Collecting duct cells: 82.8;Paneth cells: 77.0;Proximal enterocytes: 298.9;Respiratory ciliated cells: 144.8;Squamous epithelial cells: 86.9"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"basophil: 3.5;eosinophil: 6.6;memory B-cell: 10.9;naive B-cell: 6.8"	"Group enriched"	"Detected in many"	5	"B-cells: 10.9;granulocytes: 6.6"	"Group enriched"	"Detected in some"	16	"OE19: 69.3;T-47d: 104.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA046644			Approved	Nucleoplasm,Nucleoli		NA	NA			"Cluster 19: B-cells - Humoral immune response"	"Cluster 31: Skin - Epidermis development"	"Cluster 6: T47d - Mammary gland"	"Cluster 45: Enterocytes - Digestion"	"Nucleoplasm, Nucleoli"		"HPA046644: AB_2797231"	"unprognostic (8.18e-2)"	"unprognostic (3.83e-3)"	"unprognostic (2.33e-1)"	"unprognostic (1.32e-2)"	"unprognostic (3.55e-1)"	"unprognostic (4.91e-2)"	"unprognostic (1.53e-1)"	"unprognostic (1.13e-2)"	"unprognostic (2.43e-1)"	"unprognostic (1.20e-1)"	"unprognostic (1.64e-1)"	"unprognostic (1.38e-1)"	"prognostic favorable (7.94e-7)"	"unprognostic (1.03e-3)"	"unprognostic (1.26e-1)"	"unprognostic (1.14e-1)"	"prognostic favorable (1.66e-4)"	0.4	0.1	6.4	1.0	7.2	0.2	6.1	18.3	7.1	4.8	3.6	8.9	24.7	3.3	0.5	37.0	2.0	6.5	0.2	5.1	4.5	10.8	0.9	1.6	0.6	5.9	5.3	1.0	6.9	0.4	3.3	0.4	6.0	2.3	4.5	0.2	8.6	2.1	0.3	54.2	34.8	0.5	4.8	0.8	20.1	1.1	5.3	0.1	2.4	0.0	1.8	6.5	10.1	4.9	0.0	0.3	0.0	0.3	0.0	0.0	3.6	0.0	0.0	0.0	0.0	0.5	2.4	0.0	0.5	0.0	0.0	0.4	0.0	0.0	0.0	0.1	0.9	0.0	0.0	0.0	0.1	0.5	0.8	0.1	0.3	0.0	0.0	0.0	0.0	1.1	1.6	0.0	0.0	4.2	0.4	0.3	0.1	69.3	0.0	0.4	0.0	3.6	0.0	1.6	5.2	0.1	0.0	3.1	0.0	0.1	104.4	1.1	0.0	0.0	0.0	0.3	0.0	0.5	0.0	0.0	0.0	0.0	0.0	3.5	0.4	6.6	1.6	0.0	0.0	10.9	0.1	0.7	0.7	6.8	0.0	1.0	0.2	0.2	0.0	0.1	0.0	0.7	6.4	7.2	18.3	7.1	5.1	4.5	5.9	5.3	6.0	4.8	5.3	4.9	0.7	3.2	5.0	5.2	3.7	1.8	3.3	22.9	1.2	4.6	24.2	15.2	0.6	37.1	34.8	82.8	0.0	7.7	3.3	24.2	1.9	19.0	1.2	15.3	4.3	3.8	55.3	1.3	0.5	1.5	4.9	1.3	54.6	28.9	9.5	0.9	0.4	0.3	1.6	0.0	0.4	53.5	34.6	0.9	0.6	1.6	0.3	1.5	0.0	3.7	0.5	1.2	12.3	0.0	1.5	2.4	77.0	0.0	3.7	1.7	298.9	0.4	144.8	22.0	0.0	1.1	3.1	3.2	4.0	86.9	15.3	37.4	2.5	0.2	69.6	21.0
DHCR24	"DCE, KIAA0018, seladin-1"	ENSG00000116133	"24-dehydrocholesterol reductase"	Q15392	1	54849627-54887195	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adrenal gland: 1129.5;liver: 623.5"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 298.1;Alveolar cells type 2: 682.3;Hepatocytes: 1091.4;Theca cells: 442.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"ASC diff: 1031.9"	"Low region specificity"	"Detected in all"							"HPA017981, CAB037247, HPA063005"	Enhanced					NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 15: Hepatocytes - Hemostasis"			"CAB037247: AB_796187, HPA017981: AB_2732422, HPA063005: AB_2684919"	"unprognostic (2.88e-1)"	"unprognostic (1.80e-2)"	"unprognostic (4.99e-3)"	"prognostic unfavorable (1.05e-5)"	"unprognostic (1.69e-1)"	"unprognostic (2.61e-1)"	"unprognostic (1.54e-2)"	"unprognostic (1.85e-1)"	"unprognostic (1.68e-1)"	"unprognostic (1.86e-1)"	"unprognostic (6.18e-3)"	"unprognostic (3.35e-1)"	"unprognostic (7.82e-3)"	"unprognostic (5.48e-2)"	"unprognostic (1.83e-1)"	"unprognostic (1.70e-1)"	"unprognostic (3.97e-2)"	58.3	1129.5	35.7	19.8	58.5	1.6	104.8	125.3	73.0	54.9	30.4	55.6	62.2	13.1	1.6	296.1	60.4	42.2	18.0	55.9	63.9	48.6	623.5	215.9	9.4	216.2	91.3	28.5	30.5	157.9	17.0	21.6	158.9	128.6	40.5	15.8	136.2	8.3	197.7	247.6	29.6	12.6	129.3	134.1	98.9	74.2	87.9	10.1	15.4	11.1	33.9	13.5	103.9	280.7	342.1	58.5	210.6	257.1	1031.9	219.0	50.5	94.8	160.3	130.7	268.6	341.6	210.2	55.3	191.5	82.4	427.4	319.2	250.5	501.3	118.3	8.3	159.6	303.3	131.8	421.7	168.9	126.7	68.2	161.0	429.0	397.6	74.7	66.7	67.2	124.5	224.7	0.2	50.2	143.5	25.8	111.4	592.0	90.7	164.2	0.3	54.2	166.3	735.3	257.1	144.5	53.2	185.0	337.5	123.1	221.6	441.5	143.3	62.2	45.3	130.0	66.1	183.9	22.7	55.0	91.2	32.8	215.3	60.4	5.1	1.5	0.7	6.0	1.8	0.3	3.7	2.5	2.6	5.2	1.3	2.2	2.9	0.0	2.7	0.7	3.0	0.4	4.4	35.7	58.5	125.3	73.0	55.9	63.9	216.2	91.3	158.9	129.3	87.9	280.7	6.2	298.1	682.3	12.4	13.3	31.5	17.3	150.6	79.1	9.7	87.9	33.1	15.3	145.8	205.2	68.0	0.0	35.2	6.4	133.3	3.9	55.3	22.9	14.5	5.8	13.5	24.0	71.6	14.5	76.5	34.4	17.5	38.7	44.7	32.2	26.4	111.0	1091.4	28.0	5.0	8.7	39.2	69.2	68.9	8.2	77.2	14.0	9.4	14.2	1.9	6.8	3.6	2.1	5.5	62.6	48.6	27.7	7.9	1.8	52.4	22.6	14.4	136.3	6.4	0.0	1.5	23.2	5.4	14.7	145.4	80.4	30.6	10.6	442.4	35.2	45.2
DHCR7	SLOS	ENSG00000172893	"7-dehydrocholesterol reductase"	Q9UBM7	11	71428193-71452868	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 161.1"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 77.9;Granulosa cells: 81.3;Hepatocytes: 156.1;Theca cells: 103.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA044280	Approved		Supported	"Endoplasmic reticulum"		NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 15: Liver - Metabolism"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 15: Hepatocytes - Hemostasis"	"Endoplasmic reticulum"		"HPA044280: AB_10794893"	"unprognostic (1.76e-1)"	"unprognostic (1.50e-3)"	"unprognostic (1.32e-2)"	"unprognostic (7.16e-3)"	"unprognostic (2.69e-1)"	"unprognostic (2.18e-3)"	"unprognostic (8.57e-3)"	"unprognostic (3.02e-2)"	"unprognostic (4.91e-2)"	"unprognostic (1.13e-1)"	"unprognostic (1.08e-2)"	"unprognostic (5.45e-2)"	"prognostic favorable (6.93e-7)"	"unprognostic (1.73e-1)"	"unprognostic (1.01e-1)"	"unprognostic (8.15e-2)"	"prognostic unfavorable (5.67e-4)"	23.7	97.2	28.1	13.0	35.4	46.7	36.3	42.4	37.0	16.2	15.6	21.1	48.1	10.6	59.2	42.2	12.5	8.9	28.8	28.8	35.8	16.3	161.1	21.8	6.0	55.3	38.8	54.4	16.6	24.4	18.4	8.3	55.8	21.6	14.4	8.7	27.8	7.1	13.6	68.2	19.3	9.9	34.4	9.6	19.1	31.0	38.0	4.7	11.9	13.2	9.4	7.9	22.7	58.9	126.4	112.3	106.7	118.9	49.0	75.8	33.7	50.9	134.1	43.1	114.5	419.8	401.5	87.1	79.0	48.6	376.2	235.9	128.8	276.7	44.5	33.5	98.7	33.4	89.3	183.1	127.8	63.7	15.6	89.2	122.1	159.3	108.4	34.6	63.8	112.7	159.6	180.7	43.2	341.1	52.4	72.6	154.1	124.9	67.4	46.9	150.6	377.3	162.3	187.3	144.7	53.9	48.4	157.6	113.9	51.4	153.2	34.5	60.4	11.5	62.4	3.7	61.5	59.3	78.7	95.8	33.8	110.9	48.9	5.6	2.1	1.9	10.5	1.4	12.6	6.5	8.9	9.8	2.8	5.4	11.0	13.0	1.1	5.8	1.5	7.1	6.0	6.9	28.1	35.4	42.4	37.0	28.8	35.8	55.3	38.8	55.8	34.4	38.0	58.9	7.1	3.2	19.1	7.2	7.1	0.8	10.1	77.9	3.4	8.4	21.8	14.9	13.1	15.7	39.2	22.0	12.5	15.5	11.9	9.9	7.9	36.9	0.1	3.9	1.5	11.8	9.5	5.2	3.2	49.9	27.6	12.8	11.7	9.3	0.0	81.3	7.9	156.1	11.9	0.0	4.5	12.3	54.9	3.8	3.3	1.7	8.4	5.6	5.4	1.0	5.8	21.2	4.1	5.0	14.7	26.7	11.5	4.9	10.0	16.5	8.9	3.8	7.6	8.7	13.1	3.9	9.0	0.5	7.0	11.9	1.1	54.2	13.8	103.6	15.0	9.5
DHDH	HUM2DD	ENSG00000104808	"Dihydrodiol dehydrogenase"	Q9UQ10	19	48933699-48944969	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	5	"intestine: 17.3;kidney: 18.0"	"Group enriched"	"Detected in many"	11	"Proximal enterocytes: 213.7;Proximal tubular cells: 77.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"basophil: 4.2"	"Group enriched"	"Detected in many"	33	"granulocytes: 4.2;T-cells: 2.3"	"Cell line enhanced"	"Detected in some"		"JURKAT: 3.2;U-266/70: 3.2;U-266/84: 2.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA044131	Approved		Approved	"Nucleoplasm,Actin filaments"		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 29: U-266 - Adaptive immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	"Nucleoplasm, Actin filaments"		"HPA044131: AB_10966968"	"unprognostic (1.54e-1)"	"unprognostic (2.72e-2)"	"unprognostic (1.07e-1)"	"prognostic unfavorable (9.91e-4)"	"unprognostic (3.33e-3)"	"unprognostic (1.45e-1)"	"unprognostic (5.81e-6)"	"unprognostic (1.56e-2)"	"unprognostic (5.88e-2)"	"unprognostic (4.96e-2)"	"unprognostic (3.30e-2)"	"unprognostic (5.08e-2)"	"prognostic favorable (3.15e-4)"	"unprognostic (2.93e-2)"	"unprognostic (1.23e-1)"	"unprognostic (1.67e-1)"	"unprognostic (1.54e-1)"	0.2	0.4	1.6	0.0	1.6	0.1	0.2	1.9	3.3	0.3	1.0	0.3	10.5	0.1	0.0	0.8	0.3	0.2	0.1	1.7	1.7	18.0	0.4	1.1	0.2	1.2	1.3	0.6	0.4	0.5	1.8	1.3	1.2	3.2	0.0	1.7	0.4	0.1	0.2	0.2	17.3	0.0	1.3	1.7	0.7	1.9	2.7	0.1	0.1	0.0	0.2	0.3	0.4	1.6	1.4	0.0	0.1	0.7	0.4	0.3	0.5	0.0	0.2	0.2	0.7	1.4	1.1	0.0	0.2	0.0	0.9	0.4	0.5	1.0	0.4	0.5	1.1	2.0	0.5	0.5	0.0	0.0	0.4	0.2	0.1	0.5	0.0	0.3	0.0	3.2	0.7	0.2	0.0	0.3	0.0	0.1	0.3	2.1	0.9	0.7	0.1	1.0	0.1	0.4	2.1	1.1	0.2	0.1	0.5	0.1	1.0	0.0	0.0	0.0	0.8	0.3	0.0	3.2	2.8	0.8	0.7	0.0	0.2	4.2	0.0	0.5	0.7	0.0	0.4	0.0	0.8	0.3	0.0	0.0	2.3	1.5	0.0	0.0	0.0	0.0	0.6	0.2	1.6	1.6	1.9	3.3	1.7	1.7	1.2	1.3	1.2	1.3	2.7	1.6	0.5	3.2	6.4	1.0	1.0	0.8	2.4	3.3	2.2	2.4	1.0	3.4	0.7	1.5	4.6	3.7	0.0	0.2	0.4	1.5	9.8	2.2	0.7	0.3	0.5	0.8	0.0	0.4	1.0	0.4	0.2	0.5	4.1	0.8	1.3	0.1	0.0	0.0	12.9	0.0	1.2	5.0	2.0	0.8	0.0	2.4	0.0	1.7	0.0	0.0	0.0	1.6	0.0	0.0	0.5	1.5	3.6	0.0	0.0	3.5	213.7	77.8	0.5	4.5	0.0	1.2	0.4	0.0	0.8	3.1	0.1	0.1	0.6	0.4	2.7	3.2
DHFR		ENSG00000228716	"Dihydrofolate reductase"	P00374	5	80626226-80654983	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Methotrexate resistance, One-carbon metabolism"	"Oxidoreductase, RNA-binding"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Erythroid cells: 145.8;Spermatocytes: 132.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB037129, HPA051465"	Uncertain		Approved	Mitochondria		NA	Yes			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Mitochondria		"CAB037129: AB_439683, HPA051465: AB_2681494"	"unprognostic (1.44e-2)"	"unprognostic (1.03e-2)"	"unprognostic (2.24e-3)"	"unprognostic (2.91e-3)"	"unprognostic (3.27e-1)"	"unprognostic (1.32e-1)"	"unprognostic (2.83e-2)"	"unprognostic (2.35e-2)"	"unprognostic (2.02e-2)"	"unprognostic (4.19e-3)"	"unprognostic (1.83e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.15e-2)"	"unprognostic (1.82e-2)"	"unprognostic (2.49e-1)"	"unprognostic (1.57e-1)"	"unprognostic (1.09e-1)"	25.2	5.3	15.3	20.7	16.5	54.3	12.0	15.8	21.9	8.0	13.3	21.4	24.5	8.6	7.0	14.1	7.4	8.5	7.2	13.8	15.5	21.3	60.1	7.5	41.5	16.6	16.6	6.6	3.2	9.1	6.3	14.4	16.6	8.9	25.3	10.3	6.8	9.5	19.6	9.8	25.1	12.0	16.5	10.3	12.2	18.5	15.8	60.7	8.2	25.8	39.5	10.3	5.7	17.7	98.1	66.6	164.8	122.7	30.7	32.0	60.6	76.5	58.1	130.2	149.0	63.8	114.6	196.9	32.5	44.6	106.0	67.0	214.4	98.6	208.5	88.2	132.1	94.8	104.5	59.5	6.6	111.7	40.3	22.3	9.9	116.9	13.0	22.2	63.9	142.0	108.3	146.7	133.5	98.2	276.5	44.9	83.6	48.3	38.5	176.7	323.3	194.1	75.1	61.5	134.3	93.7	107.9	49.9	54.6	83.5	98.5	108.6	38.5	41.0	62.0	116.0	148.3	68.2	146.6	210.3	91.5	222.1	107.7	0.2	0.3	0.2	0.5	0.6	0.2	0.5	0.6	0.8	0.5	0.5	0.5	0.6	0.8	0.5	0.5	0.8	0.9	0.6	15.3	16.5	15.8	21.9	13.8	15.5	16.6	16.6	16.6	16.5	15.8	17.7	4.1	6.4	11.7	4.9	21.4	6.9	6.5	6.0	4.0	3.5	8.9	8.9	13.0	4.3	6.1	14.7	2.1	35.2	7.4	19.3	9.8	7.4	7.4	10.8	7.7	7.7	4.9	145.8	7.3	3.7	47.3	12.0	11.7	8.0	2.5	22.0	10.0	48.3	44.7	3.3	7.2	19.1	4.1	18.9	4.4	6.4	14.0	12.8	0.0	4.7	7.1	14.5	13.4	3.5	6.0	4.7	10.3	16.1	60.9	2.9	26.6	40.0	6.9	3.2	13.1	9.0	12.5	132.2	49.8	21.2	5.5	13.3	11.8	12.3	38.1	12.1
DHFR2	"DHFRL1, DHFRP4, FLJ16119"	ENSG00000178700	"Dihydrofolate reductase 2"	Q86XF0	3	94047836-94063389	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"One-carbon metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 12.8;Ductal cells: 6.3;Respiratory ciliated cells: 8.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enriched"	"Detected in all"	13	"hTERT-RPE1: 154.6"									HPA051465	Uncertain		Approved	Mitochondria		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 11: RPE1 & U-87MG - Synaptic function"	"Cluster 7: Non-specific - Mitochondria"	Mitochondria		"HPA051465: AB_2681494"	"unprognostic (1.16e-1)"	"unprognostic (1.15e-1)"	"unprognostic (1.10e-2)"	"unprognostic (3.50e-2)"	"unprognostic (2.07e-1)"	"unprognostic (1.38e-1)"	"unprognostic (5.92e-2)"	"unprognostic (1.33e-1)"	"unprognostic (1.12e-1)"	"unprognostic (4.62e-2)"	"unprognostic (2.95e-1)"	"unprognostic (1.52e-1)"	"prognostic favorable (2.30e-6)"	"unprognostic (1.63e-1)"	"unprognostic (1.79e-1)"	"unprognostic (1.13e-1)"	"unprognostic (2.96e-2)"	3.3	4.9	3.9	3.8	5.2	1.8	5.3	6.0	5.2	5.2	4.8	4.2	4.1	7.9	6.4	3.5	6.3	5.1	3.7	4.1	4.1	5.9	6.7	4.5	5.7	4.8	4.2	10.1	5.3	6.5	2.5	3.2	5.0	6.4	4.6	3.2	4.4	4.9	1.4	4.2	4.9	5.4	4.2	4.9	4.7	4.7	4.4	5.7	6.7	2.1	4.6	3.3	2.4	6.5	3.8	6.5	4.2	4.4	5.7	7.2	1.7	5.7	6.0	2.8	3.2	1.4	5.7	2.5	3.8	3.0	3.7	5.0	3.3	3.9	4.4	8.5	1.8	3.1	2.9	3.4	6.0	2.2	3.6	7.6	5.1	3.3	4.2	154.6	2.9	11.9	1.6	5.6	3.7	4.5	10.8	1.2	3.7	10.8	6.7	2.7	5.7	4.1	4.1	1.9	5.4	5.3	8.3	2.2	9.6	3.3	5.6	3.1	4.8	4.4	7.4	1.8	2.2	4.1	4.4	3.5	4.4	5.5	6.2	2.2	1.1	2.0	1.8	1.7	3.3	1.8	2.4	2.9	0.7	2.2	3.2	3.0	1.7	1.4	1.8	2.1	3.2	1.3	3.9	5.2	6.0	5.2	4.1	4.1	4.8	4.2	5.0	4.2	4.4	6.5	2.8	12.8	5.8	0.0	0.9	0.0	0.0	0.0	0.0	0.0	3.6	3.4	0.0	0.0	1.8	3.7	0.0	2.4	2.3	0.0	3.9	6.3	0.0	3.5	4.4	2.5	0.0	0.0	0.0	5.5	1.7	2.5	0.0	2.9	2.5	4.9	0.0	0.0	3.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	2.6	0.0	0.0	0.0	0.0	4.6	0.0	0.0	0.4	0.0	0.0	5.6	8.7	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.8	1.3	3.5	0.0	0.0
DHODH		ENSG00000102967	"Dihydroorotate dehydrogenase (quinone)"	Q02127	16	72008588-72027664	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Pyrimidine biosynthesis"	Oxidoreductase	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	8	"liver: 105.9"	"Cell type enriched"	"Detected in many"	5	"Hepatocytes: 124.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA010123, HPA011942"	Approved		Enhanced	Nucleoplasm,Mitochondria,Cytosol		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 85: Liver - Metabolism"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 15: Hepatocytes - Hemostasis"	Mitochondria	"Nucleoplasm, Cytosol"	"HPA010123: AB_1847648, HPA011942: AB_1847649"	"unprognostic (4.88e-2)"	"unprognostic (1.10e-1)"	"unprognostic (1.90e-1)"	"unprognostic (2.12e-2)"	"unprognostic (1.41e-3)"	"unprognostic (2.10e-1)"	"unprognostic (4.27e-2)"	"unprognostic (1.31e-2)"	"unprognostic (1.26e-1)"	"unprognostic (2.68e-1)"	"unprognostic (2.14e-1)"	"unprognostic (6.40e-2)"	"unprognostic (9.26e-3)"	"unprognostic (1.98e-1)"	"unprognostic (1.97e-1)"	"unprognostic (1.14e-1)"	"unprognostic (1.81e-1)"	7.4	4.8	3.1	4.2	3.6	3.9	5.8	3.7	3.7	4.0	3.7	5.4	3.9	5.4	2.8	4.2	6.1	2.3	13.8	2.9	2.5	8.0	105.9	3.9	4.2	3.4	3.3	4.9	4.2	6.2	2.5	2.7	3.3	4.0	5.8	3.2	5.4	4.5	10.0	4.5	3.1	5.7	2.1	4.1	4.1	3.6	3.4	3.9	4.1	8.1	5.5	3.9	3.4	5.2	12.5	25.7	6.9	12.1	3.8	5.0	13.9	10.5	4.2	15.6	11.6	20.4	11.1	27.8	13.6	5.7	8.6	12.5	13.7	11.4	18.2	6.0	13.3	15.4	12.6	20.3	10.6	21.4	10.8	4.9	11.3	18.6	19.7	4.7	11.3	18.3	23.9	4.4	9.7	32.7	20.2	17.0	15.9	21.1	10.0	24.9	9.6	29.4	9.4	7.8	8.5	10.2	14.1	14.8	6.8	8.7	13.0	10.3	5.1	14.1	8.3	13.1	15.2	8.8	18.7	46.3	7.1	22.4	12.8	6.1	8.4	1.0	9.4	8.8	12.9	12.0	8.5	9.3	14.5	11.7	11.7	12.6	2.1	10.1	6.3	13.5	8.0	7.2	3.1	3.6	3.7	3.7	2.9	2.5	3.4	3.3	3.3	2.1	3.4	5.2	6.3	3.2	13.1	1.6	7.1	5.6	7.8	11.2	6.8	5.6	6.6	7.1	14.8	15.7	5.5	7.3	4.2	12.3	6.9	1.6	5.9	10.3	2.9	3.8	6.3	9.1	1.2	7.8	2.0	5.1	12.4	7.4	2.6	3.2	8.2	10.2	5.3	124.1	7.9	3.3	2.3	6.6	10.2	6.0	3.1	3.6	2.8	3.3	12.4	1.0	3.8	5.2	8.2	4.0	4.4	5.9	2.4	2.2	4.6	11.2	1.0	20.8	8.1	5.2	0.0	9.7	9.1	6.8	8.1	5.0	3.8	2.9	4.3	13.5	6.7	4.2
DHRS11	"MGC4172, SDR24C1"	ENSG00000278535	"Dehydrogenase/reductase 11"	Q6UWP2	17	36591879-36600804	"Enzymes, Predicted intracellular proteins, Predicted secreted proteins"	"Lipid metabolism, Steroid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	10	"intestine: 216.0"	"Cell type enhanced"	"Detected in many"		"Cone photoreceptor cells: 129.3;Distal enterocytes: 317.3;Paneth cells: 154.2;Proximal enterocytes: 527.9;Undifferentiated cells: 148.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041226, HPA048236, HPA053623"	Enhanced		Approved	"Golgi apparatus,Cytosol"	"Secreted to digestive system"	NA	NA		42000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 56: Intestine - Transmembrane transport"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 45: Enterocytes - Digestion"	Cytosol	"Golgi apparatus"	"HPA041226: AB_2677372, HPA048236: AB_2680322, HPA053623: AB_2682209"	"unprognostic (2.00e-3)"	"unprognostic (1.22e-2)"	"unprognostic (1.06e-2)"	"unprognostic (3.74e-1)"	"unprognostic (1.61e-3)"	"unprognostic (2.03e-2)"	"unprognostic (1.78e-1)"	"unprognostic (1.80e-2)"	"unprognostic (3.67e-1)"	"unprognostic (5.94e-2)"	"unprognostic (1.33e-2)"	"unprognostic (4.11e-2)"	"prognostic favorable (3.24e-4)"	"unprognostic (1.45e-1)"	"unprognostic (1.70e-1)"	"unprognostic (2.16e-2)"	"unprognostic (9.35e-2)"	10.0	10.5	6.9	5.4	7.9	4.4	10.9	6.7	9.8	9.5	9.0	74.3	216.0	5.7	1.9	14.6	7.3	2.4	17.2	8.6	9.0	21.9	14.8	4.3	2.4	7.4	7.5	5.1	15.4	9.5	13.3	2.0	7.9	8.0	57.1	22.4	10.3	4.5	16.7	14.4	177.0	6.3	6.6	4.7	11.7	17.0	8.2	2.1	11.9	9.9	3.6	6.8	10.5	7.7	13.9	10.0	3.6	13.8	1.2	2.5	10.6	3.8	2.6	11.9	10.7	22.2	10.1	0.8	1.9	4.0	4.8	13.9	11.5	6.7	10.5	7.1	15.2	3.7	10.1	35.6	5.5	3.0	1.2	2.2	7.3	8.6	6.5	1.9	8.8	11.2	36.1	9.3	5.9	12.5	12.6	5.5	4.5	14.2	0.4	15.2	12.8	22.0	9.9	11.4	10.4	4.9	16.0	12.9	33.3	6.6	19.1	3.6	4.8	1.6	18.2	7.6	10.0	14.1	16.7	4.4	6.5	9.3	5.5	0.1	0.1	0.4	0.1	0.3	0.0	0.0	0.2	0.1	0.0	0.1	0.3	0.1	0.1	0.0	0.0	0.0	0.7	0.0	6.9	7.9	6.7	9.8	8.6	9.0	7.4	7.5	7.9	6.6	8.2	7.7	9.1	0.0	1.5	4.2	3.3	4.2	8.9	2.8	4.0	20.7	14.6	13.3	9.6	2.8	2.4	7.3	129.3	7.9	1.4	317.3	58.7	10.7	22.9	10.2	5.0	6.7	12.1	31.5	8.2	11.4	4.7	3.4	8.6	6.8	0.0	5.3	5.3	12.7	3.5	16.8	9.6	72.2	2.0	1.9	4.2	30.5	4.1	2.6	19.6	2.8	3.6	15.8	1.0	4.0	2.0	7.5	154.2	5.3	9.1	11.7	527.9	43.1	3.8	71.0	0.0	5.9	5.9	27.7	6.5	12.0	6.0	7.0	3.1	9.3	148.5	15.2
DHRS3	"RDH17, retSDR1, Rsdr1, SDR1, SDR16C1"	ENSG00000162496	"Dehydrogenase/reductase 3"	O75911	1	12567910-12618210	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 323.7"	"Cell type enhanced"	"Detected in many"		"Late spermatids: 409.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	6	"gdT-cell: 86.8;MAIT T-cell: 63.1;memory CD4 T-cell: 46.9;memory CD8 T-cell: 41.0;myeloid DC: 24.0;naive CD4 T-cell: 79.2;naive CD8 T-cell: 50.1;NK-cell: 41.1"	"Group enriched"	"Detected in many"	5	"dendritic cells: 24.0;NK-cells: 41.1;T-cells: 86.8"	"Cell line enhanced"	"Detected in many"		"A549: 107.4;CAPAN-2: 206.9;hTERT-RPE1: 196.7;SK-BR-3: 104.6;WM-115: 192.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA010844	Supported		Approved	Nucleoli,Mitochondria		NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 85: Liver - Metabolism"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 31: Spermatids - Spermatogenesis"	"Nucleoli, Mitochondria"		"HPA010844: AB_1847653"	"unprognostic (7.83e-2)"	"unprognostic (2.11e-1)"	"unprognostic (1.82e-2)"	"unprognostic (1.74e-3)"	"unprognostic (1.87e-1)"	"unprognostic (3.68e-2)"	"unprognostic (2.25e-3)"	"unprognostic (5.06e-2)"	"unprognostic (3.40e-2)"	"unprognostic (5.18e-2)"	"unprognostic (1.29e-2)"	"unprognostic (1.92e-1)"	"unprognostic (1.80e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.76e-1)"	"prognostic favorable (2.65e-4)"	"unprognostic (5.48e-2)"	150.9	21.6	38.3	18.6	37.8	13.8	115.8	34.8	41.1	89.8	96.3	60.8	50.2	34.6	25.3	117.1	53.9	33.5	73.2	38.0	38.0	87.8	323.7	56.4	18.0	57.2	37.8	38.8	108.4	31.3	48.8	19.6	40.1	169.6	21.2	8.6	67.0	48.2	76.2	71.9	52.5	16.8	40.6	27.0	87.1	20.2	41.3	10.4	121.2	24.7	8.9	73.0	107.0	44.2	18.1	107.4	0.1	42.7	54.9	5.0	11.9	6.2	0.3	0.2	0.4	11.8	206.9	0.1	5.2	57.7	17.6	79.9	21.4	10.6	0.2	0.1	36.3	16.5	11.3	57.3	8.5	0.3	0.3	27.9	13.5	0.3	0.5	196.7	18.0	0.7	24.3	0.3	0.3	3.0	4.4	1.0	6.8	18.5	40.3	0.5	0.1	20.2	0.1	36.6	1.3	2.0	35.0	104.6	6.6	13.2	10.3	4.8	13.5	0.5	2.2	30.3	0.4	3.3	0.2	0.2	23.9	1.4	192.8	9.2	0.8	0.1	86.8	0.5	63.1	0.6	46.9	41.0	24.0	0.7	79.2	50.1	4.7	41.1	1.1	3.0	1.4	48.2	38.3	37.8	34.8	41.1	38.0	38.0	57.2	37.8	40.1	40.6	41.3	44.2	139.5	96.1	55.9	26.8	3.4	25.6	136.0	114.8	59.2	2.0	17.5	22.6	42.3	45.8	93.4	20.2	18.8	34.4	35.5	83.8	23.5	99.3	99.6	69.8	50.2	54.1	25.1	23.6	3.7	163.1	45.0	56.4	32.1	83.7	15.8	2.6	73.5	181.3	67.1	0.0	3.3	33.0	42.7	69.6	8.4	409.5	22.7	43.6	7.2	17.8	11.5	15.3	38.1	1.0	0.6	129.6	69.5	9.8	3.5	76.2	112.6	52.9	82.8	2.4	0.0	10.5	30.8	1.9	1.4	51.7	27.0	26.3	28.3	7.9	33.0	156.8
DHRS4	"FLJ11008, humNRDR, SCAD-SRL, SDR-SRL, SDR25C2"	ENSG00000157326	"Dehydrogenase/reductase 4"	Q9BTZ2	14	23953734-23969279	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Proximal tubular cells: 235.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"											HPA023972	Uncertain		Approved	"Nuclear membrane,Vesicles"		NA	NA			"Cluster 25: Monocytes - Inflammatory response"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Vesicles	"Nuclear membrane"	"HPA023972: AB_1854890"	"unprognostic (1.21e-2)"	"unprognostic (2.59e-1)"	"unprognostic (3.46e-2)"	"unprognostic (3.79e-3)"	"unprognostic (1.97e-1)"	"unprognostic (1.66e-1)"	"unprognostic (7.35e-3)"	"unprognostic (1.61e-3)"	"unprognostic (2.66e-1)"	"unprognostic (1.19e-2)"	"unprognostic (1.06e-2)"	"unprognostic (7.65e-2)"	"prognostic favorable (4.55e-6)"	"unprognostic (2.03e-2)"	"unprognostic (1.48e-1)"	"unprognostic (2.03e-1)"	"unprognostic (5.68e-2)"	34.1	45.8	8.6	10.4	9.2	6.9	34.5	8.8	9.7	30.5	10.1	43.5	34.0	27.1	5.2	45.8	23.6	5.9	49.1	8.3	8.6	92.0	109.7	28.0	10.2	9.2	8.6	33.0	40.3	8.8	19.3	5.3	9.2	31.9	13.5	3.9	31.2	8.4	62.2	44.7	38.6	8.3	8.6	32.2	33.7	37.9	9.0	9.6	25.4	14.0	8.5	30.5	33.1	9.5	15.1	29.6	10.4	17.2	16.6	18.5	0.1	27.4	15.3	11.5	9.1	6.5	16.5	13.3	14.3	14.6	7.6	18.1	8.6	12.3	10.1	34.6	16.5	7.8	23.5	36.6	9.5	11.6	45.2	18.0	14.8	9.2	20.8	12.3	14.4	19.6	11.8	30.4	15.8	52.3	21.1	10.7	9.9	18.9	30.3	33.8	18.0	41.4	12.1	17.1	19.9	16.1	27.7	17.6	13.8	6.8	16.0	14.6	25.5	13.3	13.8	13.9	9.0	22.8	22.8	3.5	11.8	12.6	13.6	5.4	54.4	6.0	18.0	45.8	21.4	21.5	20.3	18.2	47.4	18.5	20.1	19.5	2.3	18.1	25.5	39.4	19.4	36.2	8.6	9.2	8.8	9.7	8.3	8.6	9.2	8.6	9.2	8.6	9.0	9.5	16.6	16.0	30.5	6.2	12.5	12.5	10.4	15.7	55.2	5.1	22.2	31.9	35.4	17.2	21.3	14.7	0.0	9.6	17.8	34.2	78.2	6.4	50.4	13.1	11.6	14.6	19.2	20.8	2.6	9.8	6.0	23.7	34.7	7.8	13.9	10.5	20.0	68.1	30.4	6.7	2.1	50.1	8.2	29.2	13.5	66.1	11.1	35.9	5.4	3.7	33.2	18.1	47.4	4.0	5.0	5.3	22.3	17.3	24.6	11.2	51.8	235.4	23.2	1.8	6.6	13.5	18.1	59.4	1.9	61.6	13.4	3.8	18.1	22.9	71.8	9.0
DHRS9	"3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4"	ENSG00000073737	"Dehydrogenase/reductase 9"	Q9BPW9	2	169064789-169096167	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid metabolism, Steroid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 53.9;intestine: 70.4"	"Cell type enhanced"	"Detected in many"		"Club cells: 229.3;Distal enterocytes: 261.2;Early spermatids: 153.2;Paneth cells: 299.9;Respiratory ciliated cells: 155.9;Syncytiotrophoblasts: 267.5;Urothelial cells: 249.2"	"Cancer enhanced"	"Detected in many"		"pancreatic cancer: 16.6"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	6	"basophil: 258.3;eosinophil: 99.2;neutrophil: 77.3"	"Lineage enriched"	"Detected in many"	10	"granulocytes: 258.3"	"Cell line enhanced"	"Detected in some"		"hTERT-RPE1: 22.8;HUVEC TERT2: 21.5;NB-4: 33.7;THP-1: 98.0;TIME: 49.9;U-2197: 31.4"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"HPA036491, HPA036667"	Approved				"Intracellular and membrane"	NA	NA			"Cluster 10: Basophils - Unknown function"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 53: Intestinal epithelial cells - Unknown function"			"HPA036491: AB_10673498, HPA036667: AB_10670237"	"unprognostic (1.15e-1)"	"unprognostic (3.82e-3)"	"unprognostic (1.15e-1)"	"unprognostic (1.85e-1)"	"unprognostic (4.80e-2)"	"unprognostic (2.35e-1)"	"unprognostic (3.24e-2)"	"unprognostic (1.40e-1)"	"unprognostic (3.18e-1)"	"unprognostic (3.62e-4)"	"prognostic unfavorable (2.73e-4)"	"unprognostic (2.72e-1)"	"unprognostic (3.23e-1)"	"unprognostic (1.85e-2)"	"unprognostic (1.34e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.41e-1)"	10.0	0.2	2.2	12.5	2.4	8.5	5.1	3.0	2.6	8.6	1.6	70.4	1.9	1.2	0.9	28.2	1.0	5.7	53.9	2.5	2.3	0.3	3.1	7.1	20.2	4.2	3.2	0.7	0.4	0.2	0.4	2.8	4.3	0.8	46.2	1.2	6.1	0.5	0.3	3.3	5.7	4.2	3.8	7.6	10.8	11.3	3.2	2.2	0.3	0.8	26.8	17.5	10.1	4.5	0.0	0.7	0.0	0.0	2.5	10.2	0.0	0.0	0.1	0.0	0.0	0.0	1.1	0.1	0.0	0.0	6.5	1.7	0.0	1.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	8.9	1.0	0.4	0.5	1.3	6.1	22.8	21.5	0.0	1.0	0.0	0.0	0.0	0.1	33.7	0.0	0.3	8.8	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.0	98.0	49.9	0.1	0.2	31.4	0.2	0.1	0.0	0.0	0.8	18.9	0.0	258.3	21.0	99.2	0.0	25.0	0.6	6.5	0.0	0.0	21.6	5.0	0.1	0.0	77.3	0.4	5.1	1.6	0.0	5.9	2.2	2.4	3.0	2.6	2.5	2.3	4.2	3.2	4.3	3.8	3.2	4.5	0.3	0.0	1.3	0.0	1.4	1.7	19.3	72.4	0.0	0.0	0.1	0.4	24.4	0.0	229.3	0.0	0.0	2.5	0.0	261.2	0.0	4.6	153.2	0.5	0.0	0.6	1.8	0.8	0.2	25.3	1.3	1.5	7.7	0.1	91.0	0.0	0.0	0.6	25.0	0.0	0.2	51.6	36.7	10.2	38.8	45.5	1.2	16.6	0.0	19.7	3.5	3.9	0.0	0.0	0.2	68.6	299.9	0.4	6.4	6.5	1.5	0.1	155.9	0.1	6.6	0.2	10.9	1.1	0.6	0.3	1.4	267.5	3.8	0.0	8.2	249.2
DHTKD1	"CMT2Q, DKFZP762M115, KIAA1630, MGC3090"	ENSG00000181192	"Dehydrogenase E1 and transketolase domain containing 1"	Q96HY7	10	12068954-12123221	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	Glycolysis	Oxidoreductase	"Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 129.5"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 227.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"T-47d: 102.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA037949, HPA037950, HPA066098"	Enhanced		Supported	Mitochondria		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 6: T47d - Mammary gland"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Mitochondria		"HPA037949: AB_2675752, HPA037950: AB_10673650, HPA066098: AB_2685617"	"unprognostic (3.76e-2)"	"unprognostic (8.08e-3)"	"unprognostic (2.24e-1)"	"unprognostic (1.15e-1)"	"unprognostic (1.34e-1)"	"unprognostic (3.04e-3)"	"unprognostic (3.83e-3)"	"unprognostic (5.01e-2)"	"unprognostic (5.34e-2)"	"unprognostic (3.02e-3)"	"unprognostic (3.46e-1)"	"unprognostic (1.56e-1)"	"prognostic favorable (3.43e-4)"	"unprognostic (2.12e-1)"	"unprognostic (1.31e-1)"	"unprognostic (1.74e-2)"	"unprognostic (2.88e-3)"	10.7	8.4	8.1	6.8	10.4	3.8	8.4	12.6	8.5	8.8	11.9	10.1	7.6	6.2	6.8	7.5	6.1	5.3	13.2	7.6	8.5	42.7	129.5	5.4	8.5	9.5	8.6	10.0	18.0	12.7	5.6	7.7	9.5	12.9	10.8	7.5	13.1	5.7	18.7	5.6	6.9	5.7	8.8	7.8	10.9	4.7	9.1	10.5	11.6	23.1	9.7	6.3	6.1	11.4	27.0	20.4	29.8	23.8	18.2	10.8	35.9	13.3	8.6	23.4	20.6	13.1	15.7	19.3	4.3	8.4	10.8	37.4	31.6	10.4	26.6	10.9	14.2	10.6	7.7	10.1	17.8	4.2	3.8	13.3	7.9	13.7	5.5	9.2	13.0	23.1	16.7	15.1	6.3	52.3	14.4	7.7	16.7	24.9	4.7	24.3	9.7	16.5	15.2	6.4	7.7	34.9	26.3	46.3	15.4	31.7	102.2	15.2	5.8	7.5	5.4	15.8	9.9	13.4	10.3	12.6	9.7	7.4	12.8	23.8	6.8	15.4	4.2	9.2	4.5	13.0	3.2	2.7	11.9	9.9	3.1	4.1	19.4	14.3	17.0	17.3	5.7	4.9	8.1	10.4	12.6	8.5	7.6	8.5	9.5	8.6	9.5	8.8	9.1	11.4	6.9	12.8	38.8	21.5	21.3	5.2	6.7	5.3	10.2	13.3	13.7	8.3	31.1	28.6	7.8	16.5	10.4	35.4	23.2	14.6	19.6	10.9	3.5	8.8	17.3	8.1	11.3	21.9	12.8	11.1	25.1	8.1	21.9	20.8	8.8	45.2	11.0	227.4	10.3	26.9	17.3	18.0	4.1	15.3	10.1	4.2	12.5	13.5	5.4	17.8	13.4	10.4	8.2	15.6	20.5	12.4	9.6	12.0	22.6	9.6	9.4	62.5	5.2	19.2	13.1	10.6	7.4	6.7	3.8	16.2	6.0	13.5	8.4	21.8	16.6	7.8
DIO1	TXDI1	ENSG00000211452	"Iodothyronine deiodinase 1"	P49895	1	53891239-53911086	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Thyroid hormones biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	42	"kidney: 144.9;liver: 185.3;thyroid gland: 260.2"	"Group enriched"	"Detected in some"	5	"Hepatocytes: 61.5;Proximal tubular cells: 115.7"	"Group enriched"	"Detected in many"	8	"liver cancer: 44.7;thyroid cancer: 43.7"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	26	"Hep G2: 33.9;SK-BR-3: 79.0"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"									NA	NA				"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"				"unprognostic (4.89e-2)"	"unprognostic (4.86e-2)"	"unprognostic (1.81e-2)"	"unprognostic (1.21e-2)"	"unprognostic (1.06e-1)"	"unprognostic (2.68e-2)"	"unprognostic (3.91e-3)"	"unprognostic (6.96e-4)"	"unprognostic (6.94e-2)"	"unprognostic (4.83e-2)"	"unprognostic (8.81e-2)"	"unprognostic (1.43e-1)"	"unprognostic (3.50e-3)"	"unprognostic (9.99e-3)"	"unprognostic (3.78e-2)"	"prognostic unfavorable (5.44e-4)"	"unprognostic (3.59e-2)"	0.1	0.2	0.2	0.1	0.1	0.1	0.7	0.1	0.2	0.1	0.2	0.1	0.1	0.2	0.0	0.2	4.6	1.0	0.6	0.1	0.1	144.9	185.3	0.4	0.8	0.3	0.2	0.2	0.1	0.0	0.0	0.1	0.3	0.1	0.0	0.0	0.1	0.0	0.1	0.1	0.1	0.0	0.0	0.2	0.3	0.7	0.3	0.0	260.2	0.0	0.0	0.1	0.1	0.4	0.0	0.0	0.1	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	2.1	0.2	0.2	0.0	0.0	0.0	0.1	0.0	0.0	0.3	0.3	1.0	0.3	0.0	33.9	0.0	0.1	0.3	0.0	0.0	0.0	0.0	0.3	0.0	0.3	0.1	0.2	0.0	0.3	0.1	0.1	0.2	0.3	0.1	0.5	0.3	0.0	0.0	0.0	0.0	0.2	0.0	79.0	0.0	0.1	2.1	0.1	0.1	0.1	0.1	0.1	0.1	0.2	0.0	0.3	0.2	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.1	0.2	0.1	0.1	0.3	0.2	0.3	0.0	0.3	0.4	0.0	0.0	0.0	0.0	2.9	0.0	0.0	0.8	0.0	0.0	0.9	0.1	15.2	11.5	0.4	0.0	0.0	0.5	0.1	0.0	11.7	0.0	3.6	0.3	0.1	0.4	0.0	0.0	0.6	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.4	61.5	0.5	0.0	0.5	0.0	0.0	2.2	0.0	5.3	0.0	0.7	0.0	1.0	0.0	0.0	0.0	0.5	0.7	0.0	0.0	0.0	0.0	0.2	0.0	115.7	10.2	0.0	0.0	0.0	0.4	0.6	0.2	0.0	0.0	2.3	0.3	0.1	0.0	0.0
DIO2	"SelY, TXDI2"	ENSG00000211448	"Iodothyronine deiodinase 2"	Q92813	14	80197526-80387757	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Thyroid hormones biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"cervix: 163.9;thyroid gland: 355.8"	"Cell type enhanced"	"Detected in many"		"Breast glandular cells: 150.7;Endometrial stromal cells: 158.3;Extravillous trophoblasts: 523.3;Muller glia cells: 246.4"	"Cancer enriched"	"Detected in many"	5	"thyroid cancer: 34.8"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BJ: 80.8;fHDF/TERT166: 41.8;HeLa: 95.4;HHSteC: 44.2;SiHa: 168.1;SK-BR-3: 35.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA048002			Approved	"Nucleoplasm,Vesicles,Plasma membrane"		NA	NA				"Cluster 1: Thyroid gland - Transcription"	"Cluster 20: HeLa - Mitochondria"	"Cluster 38: Extravillous trophoblasts - Unknown function"	"Nucleoplasm, Vesicles"	"Plasma membrane"	"HPA048002: AB_2680230"	"unprognostic (1.22e-1)"	"unprognostic (1.69e-1)"	"prognostic favorable (1.67e-4)"	"prognostic favorable (4.62e-6)"	"unprognostic (2.76e-1)"	"unprognostic (1.22e-1)"	"unprognostic (2.22e-1)"	"unprognostic (2.17e-1)"	"unprognostic (2.07e-1)"	"unprognostic (8.78e-2)"	"unprognostic (3.68e-2)"	"unprognostic (2.48e-1)"	"unprognostic (1.00e-3)"	"unprognostic (5.08e-2)"	"unprognostic (3.43e-1)"	"unprognostic (8.40e-2)"	"unprognostic (7.15e-2)"	1.5	3.0	18.0	0.6	15.3	0.1	15.3	15.0	24.6	163.9	5.9	1.3	1.3	40.2	0.5	58.9	0.7	5.1	11.9	17.1	13.0	5.0	0.1	1.6	0.8	13.6	19.2	0.2	1.8	6.6	31.6	14.5	17.4	9.0	1.7	7.4	33.3	30.4	6.5	7.1	1.5	4.5	5.5	0.6	5.3	4.7	13.3	1.2	355.8	70.7	33.1	6.0	25.0	16.6	0.2	9.5	0.0	0.0	0.5	1.4	0.3	80.8	16.6	6.2	0.9	0.0	0.3	0.2	0.2	41.8	0.3	1.7	2.9	0.0	6.1	0.0	0.2	0.0	95.4	0.0	44.2	0.0	0.2	5.1	0.0	1.2	0.0	3.9	1.4	0.0	0.0	0.8	0.5	1.9	0.1	0.1	1.7	0.0	0.5	0.8	3.9	0.1	0.0	0.8	0.0	0.2	168.1	35.3	0.3	7.1	0.1	0.0	0.8	0.3	7.0	17.4	20.1	2.8	0.0	0.0	7.7	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	18.0	15.3	15.0	24.6	17.1	13.0	13.6	19.2	17.4	5.5	13.3	16.6	0.1	0.0	0.5	52.9	0.3	2.9	0.1	0.0	2.2	3.3	150.7	34.4	1.9	0.0	0.0	0.0	0.0	4.8	0.5	0.2	0.0	0.0	29.5	14.2	158.3	2.3	0.0	0.0	1.0	0.0	523.3	24.6	0.0	15.6	0.0	0.1	0.7	0.2	9.2	1.7	1.0	0.5	0.0	1.3	5.7	12.5	3.4	1.3	5.4	4.7	0.0	246.4	0.0	8.5	1.4	1.0	0.0	4.1	0.3	0.3	0.0	0.0	0.0	7.8	0.0	69.1	6.5	9.7	0.7	8.9	3.0	28.2	1.7	0.9	0.1	0.1
DIO3	TXDI3	ENSG00000197406	"Iodothyronine deiodinase 3"	P55073	14	101561351-101563452	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins"	"Thyroid hormones biosynthesis"	Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"cervix: 25.0;placenta: 17.8"	"Cell type enhanced"	"Detected in some"		"Endothelial cells: 7.8;Fibroblasts: 27.9;Leydig cells: 10.8;Muller glia cells: 8.1;Peritubular cells: 7.5;Skeletal myocytes: 16.3;Syncytiotrophoblasts: 28.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	10	"AF22: 54.2"	"Low region specificity"	"Detected in many"			"Region enhanced"	"Detected in some"		"amygdala: 4.4;hippocampal formation: 5.6"	HPA073684			Supported	Vesicles		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 12: NES - Nervous system development"	"Cluster 33: Fibroblasts - ECM organization"	Vesicles		"HPA073684: "	"unprognostic (4.52e-3)"	"unprognostic (1.80e-1)"	"unprognostic (3.04e-3)"	"unprognostic (3.48e-1)"	"unprognostic (5.16e-2)"	"unprognostic (1.50e-1)"	"unprognostic (4.24e-2)"	"unprognostic (8.11e-2)"	"unprognostic (2.58e-1)"	"unprognostic (6.24e-2)"	"unprognostic (2.34e-1)"	"unprognostic (2.52e-1)"	"unprognostic (7.46e-5)"	"unprognostic (4.82e-3)"	"unprognostic (2.43e-1)"	"unprognostic (1.11e-4)"	"unprognostic (9.80e-3)"	5.0	0.4	0.5	1.8	1.2	0.0	3.2	0.2	1.2	25.0	0.2	1.7	0.0	6.5	0.6	1.8	6.7	3.0	0.6	0.6	0.2	0.3	3.9	2.6	1.3	1.3	0.3	13.6	1.5	0.0	0.7	17.8	0.3	3.2	0.4	0.7	1.7	2.2	1.6	3.5	1.7	0.9	0.4	0.6	1.6	1.3	3.3	0.2	4.1	3.0	0.1	5.2	15.4	0.4	0.0	0.2	54.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.1	0.1	0.6	0.0	0.0	0.1	0.0	0.0	1.0	1.3	0.8	0.0	0.0	5.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	1.2	0.2	1.2	0.6	0.2	1.3	0.3	0.3	0.4	3.3	0.4	0.4	0.0	0.0	0.0	0.0	0.4	0.0	0.2	0.0	0.0	0.1	0.6	0.4	0.0	0.0	0.0	0.0	1.9	0.0	5.9	0.0	0.6	0.3	0.4	4.9	7.8	0.0	0.0	0.1	0.0	2.5	27.9	0.0	0.1	0.0	0.0	0.0	0.0	2.9	0.0	0.0	0.5	0.0	0.0	0.7	0.6	10.8	0.1	0.0	0.0	0.6	8.1	0.0	0.0	0.0	0.9	1.1	7.5	0.0	0.8	0.0	0.0	0.0	0.2	0.0	16.3	0.7	0.1	0.2	0.2	0.1	28.3	0.2	0.1	0.3	0.4
DLD	"DLDH, E3, GCSL, LAD, OGDC-E3"	ENSG00000091140	"Dihydrolipoamide dehydrogenase"	P09622	7	107891162-107931730	"Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"tongue: 357.0"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 356.2;Distal tubular cells: 226.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA044849	Supported		Approved	Nucleoplasm,Mitochondria		NA	NA		10000000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria	Nucleoplasm	"HPA044849: AB_2679111"	"unprognostic (2.01e-3)"	"unprognostic (2.26e-1)"	"unprognostic (1.27e-2)"	"unprognostic (9.27e-2)"	"unprognostic (5.01e-3)"	"unprognostic (9.27e-2)"	"unprognostic (2.48e-1)"	"unprognostic (2.83e-2)"	"unprognostic (1.19e-1)"	"unprognostic (3.95e-2)"	"unprognostic (9.43e-2)"	"unprognostic (7.35e-2)"	"prognostic favorable (7.58e-9)"	"unprognostic (4.08e-2)"	"unprognostic (1.88e-1)"	"unprognostic (4.45e-3)"	"unprognostic (1.18e-1)"	108.7	98.9	22.7	42.1	23.7	54.0	49.0	27.1	29.1	36.3	35.6	109.0	81.8	45.3	21.2	94.1	34.3	48.5	264.1	23.1	29.5	153.3	112.8	39.3	50.1	27.1	27.4	30.0	49.2	136.7	27.8	43.1	26.6	45.7	99.3	35.0	50.2	50.3	295.0	38.9	71.9	67.7	24.9	38.4	80.5	31.3	25.7	43.2	64.2	357.0	67.5	66.1	32.7	23.4	171.4	134.5	74.8	127.9	104.6	91.4	88.4	96.5	80.8	110.6	86.2	159.5	95.5	165.9	159.6	103.0	177.7	110.9	150.2	135.8	166.1	111.1	88.4	116.9	175.6	116.7	80.3	194.7	116.0	104.8	97.6	116.4	63.4	72.3	134.0	137.0	298.5	119.7	121.8	188.1	161.8	138.9	87.4	206.0	98.2	113.1	117.8	225.9	151.8	250.8	92.3	99.9	156.3	262.1	143.9	149.9	100.5	165.8	87.9	120.7	97.3	238.1	149.4	89.3	187.1	114.6	115.0	204.1	130.2	132.7	63.9	136.0	46.9	81.6	49.4	37.8	46.8	46.8	87.2	38.5	47.9	50.5	39.9	68.1	116.9	29.9	49.0	64.2	22.7	23.7	27.1	29.1	23.1	29.5	27.1	27.4	26.6	24.9	25.7	23.4	26.7	28.9	20.7	14.7	26.3	31.4	42.7	124.7	31.3	47.1	24.0	19.2	356.2	51.5	70.5	79.1	22.9	110.2	27.3	56.1	226.9	69.3	10.2	27.6	26.2	32.2	30.6	53.9	23.9	55.9	62.7	36.3	36.7	28.0	26.6	35.3	26.0	86.8	69.2	21.9	25.3	44.1	114.0	41.0	26.5	7.3	23.3	37.5	37.4	15.9	62.2	36.0	38.1	21.1	16.7	42.6	51.4	42.2	30.7	24.3	60.0	178.9	55.5	45.5	26.3	28.4	44.8	55.2	51.5	48.0	32.4	108.4	29.5	73.7	78.7	39.2
DMGDH		ENSG00000132837	"Dimethylglycine dehydrogenase"	Q9UI17	5	78997564-79236038	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	18	"kidney: 169.4;liver: 283.8"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 40.6;Hepatocytes: 104.2;Late spermatids: 33.1;Proximal tubular cells: 83.9"	"Group enriched"	"Detected in some"	12	"liver cancer: 15.6;renal cancer: 12.0"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"BJ hTERT+: 3.6;Hep G2: 7.6;hTEC/SVTERT24-B: 2.2;Karpas-707: 2.3"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"HPA036441, HPA036442, HPA077849"	Enhanced		Supported	Mitochondria		NA	NA		680000		"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Mitochondria		"HPA036441: AB_2675124, HPA036442: AB_10669792, HPA077849: AB_2686859"	"unprognostic (3.11e-2)"	"unprognostic (3.36e-1)"	"unprognostic (6.70e-2)"	"unprognostic (1.81e-1)"	"unprognostic (3.15e-1)"	"unprognostic (2.52e-3)"	"prognostic favorable (5.32e-5)"	"unprognostic (2.21e-1)"	"unprognostic (3.05e-2)"	"unprognostic (3.19e-2)"	"unprognostic (1.07e-4)"	"unprognostic (1.89e-1)"	"prognostic favorable (1.17e-5)"	"unprognostic (2.03e-2)"	"unprognostic (9.75e-4)"	"unprognostic (1.46e-1)"	"unprognostic (2.26e-1)"	8.4	4.5	1.5	0.3	1.7	0.0	2.2	1.4	1.6	1.4	3.0	1.3	0.2	2.8	12.2	1.4	1.3	2.1	1.9	1.5	2.4	169.4	283.8	0.4	0.2	1.5	1.9	2.2	1.8	0.6	2.9	0.1	2.0	1.8	0.4	1.5	0.4	1.8	2.4	0.6	0.6	1.7	1.4	0.1	1.0	2.3	2.9	0.3	4.8	1.5	0.3	1.2	0.5	1.6	0.0	0.0	0.0	0.3	0.3	0.8	0.3	0.2	3.6	0.8	1.4	0.0	0.0	0.0	0.2	1.1	0.0	0.0	0.0	0.0	1.1	0.2	0.0	0.0	0.0	7.6	1.9	0.0	0.0	1.7	2.1	2.2	1.6	1.5	0.0	0.8	0.0	2.3	0.5	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.4	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	2.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	1.7	1.4	1.6	1.5	2.4	1.5	1.9	2.0	1.4	2.9	1.6	1.3	0.0	1.1	19.9	2.9	0.1	0.5	1.0	1.8	1.9	1.4	1.8	1.0	2.8	0.8	9.2	2.1	0.3	1.9	0.7	19.6	0.4	40.6	2.6	5.0	1.2	1.2	6.1	5.8	0.7	0.1	2.7	3.6	2.7	0.0	4.1	1.8	104.2	0.1	0.0	1.5	1.2	4.1	1.6	0.4	33.1	2.5	1.7	0.0	4.7	0.2	4.3	3.1	4.5	3.3	0.8	1.4	2.6	4.5	0.9	1.6	83.9	4.7	3.7	0.0	1.7	0.7	4.9	5.3	1.8	0.3	0.3	2.9	4.4	0.9	0.8
DOHH	"HLRC1, MGC4293"	ENSG00000129932	"Deoxyhypusine hydroxylase"	Q9BU89	19	3490821-3500674	"Enzymes, Predicted intracellular proteins"	"Hypusine biosynthesis"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041953, HPA076271"	Approved		Approved	Nucleoplasm,Nucleoli,Cytosol		NA	NA			"Cluster 26: Non-specific - Mitochondria"	"Cluster 45: Intestine - Brush border"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 39: Non-specific - Basic cellular processes"	Cytosol	"Nucleoplasm, Nucleoli"	"HPA041953: AB_10795386, HPA076271: "	"unprognostic (1.28e-1)"	"unprognostic (1.18e-1)"	"unprognostic (8.63e-2)"	"prognostic favorable (2.24e-4)"	"unprognostic (3.66e-1)"	"unprognostic (2.01e-2)"	"unprognostic (9.45e-2)"	"unprognostic (7.26e-2)"	"unprognostic (4.65e-2)"	"unprognostic (1.13e-1)"	"prognostic favorable (3.58e-4)"	"unprognostic (9.87e-3)"	"unprognostic (1.14e-3)"	"unprognostic (4.35e-2)"	"unprognostic (1.46e-1)"	"unprognostic (1.66e-1)"	"unprognostic (3.76e-3)"	7.5	8.8	15.6	4.4	18.9	8.9	6.8	18.9	18.3	6.2	9.9	8.2	17.8	7.6	0.5	11.0	6.7	1.2	12.6	14.7	15.2	11.1	10.9	6.4	3.2	20.6	19.2	6.5	8.5	2.5	8.4	2.2	18.8	7.5	1.0	1.3	6.9	2.1	18.9	10.5	11.5	1.3	16.5	7.9	8.7	8.1	17.6	2.1	5.9	2.2	1.6	8.3	6.9	24.0	18.6	22.4	3.1	7.1	1.6	2.0	15.0	17.4	3.6	8.0	6.5	31.9	7.6	15.3	13.2	2.4	7.5	19.3	4.6	6.1	1.5	21.5	24.5	15.1	13.3	37.7	6.7	20.7	19.9	2.3	5.7	8.2	3.3	2.8	4.3	15.6	34.1	16.4	3.7	22.3	20.3	23.3	19.1	7.1	29.2	25.4	7.6	21.3	5.3	11.1	20.0	15.5	12.7	10.8	18.4	1.3	15.0	11.0	9.9	10.9	14.4	29.0	31.7	21.9	17.4	20.1	12.4	46.6	12.7	1.2	6.7	2.4	7.6	8.1	9.4	11.1	10.1	14.9	11.0	16.5	14.1	12.3	0.4	10.0	8.9	14.1	13.2	5.9	15.6	18.9	18.9	18.3	14.7	15.2	20.6	19.2	18.8	16.5	17.6	24.0	9.5	6.4	2.2	2.0	15.5	23.6	22.6	13.2	12.5	17.2	12.4	10.0	7.7	11.5	7.1	5.5	10.4	30.9	7.6	27.9	21.5	22.2	8.6	10.9	7.9	13.2	13.1	23.2	4.9	21.3	29.9	13.6	16.3	7.8	13.4	10.5	11.7	10.0	21.6	25.2	5.1	17.6	24.4	7.9	9.3	23.8	14.0	9.3	19.6	1.9	16.9	12.7	15.5	4.5	30.0	24.7	17.2	15.1	16.0	28.4	10.8	28.9	4.6	12.4	0.0	16.2	13.6	12.6	12.7	14.5	27.6	34.8	12.1	13.6	27.2	18.7
DPYD	DPD	ENSG00000188641	"Dihydropyrimidine dehydrogenase"	Q12882	1	97077743-97995000	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 68.5"	"Cell type enriched"	"Detected in many"	6	"Oligodendrocytes: 1712.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB033241, HPA045210"	Uncertain					NA	NA		1600000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 85: Liver - Metabolism"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"			"CAB033241: AB_2094323, HPA045210: AB_2679256"	"unprognostic (2.33e-2)"	"unprognostic (1.69e-1)"	"unprognostic (9.82e-3)"	"unprognostic (1.04e-1)"	"unprognostic (1.13e-2)"	"unprognostic (8.81e-2)"	"unprognostic (2.86e-1)"	"unprognostic (3.05e-1)"	"unprognostic (1.56e-1)"	"unprognostic (9.29e-2)"	"prognostic unfavorable (6.27e-4)"	"unprognostic (6.54e-2)"	"unprognostic (5.32e-2)"	"unprognostic (1.43e-1)"	"unprognostic (3.43e-2)"	"unprognostic (3.71e-1)"	"unprognostic (2.25e-1)"	22.2	13.2	7.2	22.6	12.8	10.3	16.7	5.7	10.4	18.8	2.4	11.9	21.9	14.9	8.4	17.1	14.3	25.7	8.9	7.4	12.9	12.6	68.5	29.6	16.6	12.4	9.4	24.0	11.8	9.2	6.2	4.5	12.1	9.9	10.1	3.3	15.0	13.4	5.8	7.1	19.4	18.2	6.9	24.7	8.4	3.7	12.9	17.0	10.3	10.1	12.0	18.2	14.2	24.4	22.2	6.2	7.8	0.2	42.4	72.5	0.1	35.2	31.9	32.1	23.6	0.0	9.2	11.7	50.6	32.9	5.1	5.2	0.0	8.3	58.7	11.6	7.3	10.0	11.1	0.2	18.8	4.5	0.6	57.5	3.0	25.7	29.3	67.7	26.8	6.8	0.4	36.4	17.0	0.0	23.6	6.4	0.9	0.2	7.5	0.1	37.1	18.6	39.4	0.1	11.1	8.8	30.1	2.5	0.3	0.8	0.0	10.2	30.9	69.2	5.0	56.4	70.6	3.0	0.1	0.2	10.2	12.6	56.2	18.2	61.1	4.1	11.6	29.5	14.8	2.2	13.3	11.0	32.7	4.9	12.5	11.1	59.8	13.3	27.1	0.9	15.8	21.9	7.2	12.8	5.7	10.4	7.4	12.9	12.4	9.4	12.1	6.9	12.9	24.4	25.5	16.0	39.1	23.8	15.4	7.6	8.8	9.4	18.8	2.5	8.4	8.3	5.3	40.0	11.5	7.3	0.0	0.2	19.2	3.3	5.9	2.5	7.0	1.5	15.2	14.7	3.0	13.3	258.6	6.4	0.2	30.0	10.7	1.7	9.5	4.5	17.2	54.2	17.1	0.0	30.5	5.5	6.1	130.4	27.0	4.0	33.5	73.7	3.6	105.9	98.1	4.8	27.8	34.2	1712.3	5.3	2.1	18.8	17.0	4.9	21.0	6.6	8.6	0.1	13.1	16.0	17.7	1.2	3.1	19.7	5.5	0.1	31.4	5.1	6.8	9.3
DUOX1	"LNOX1, NOXEF1, THOX1"	ENSG00000137857	"Dual oxidase 1"	Q9NRD9	15	45129933-45165576	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Hydrogen peroxide, Thyroid hormones biosynthesis"	"Oxidoreductase, Peroxidase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 108.5;skin 1: 81.7"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 83.3;Alveolar cells type 2: 168.6;Endometrial ciliated cells: 67.1;Glandular and luminal cells: 88.5;Respiratory ciliated cells: 64.9"	"Cancer enhanced"	"Detected in many"		"thyroid cancer: 32.4"	"Group enriched"	"Detected in many"	6	"cerebellum: 12.4;white matter: 3.2"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	5	"HaCaT: 64.4;hTCEpi: 30.5;RT4: 36.3"	"Not detected"	"Not detected"			"Region enriched"	"Detected in some"	5	"cerebellum: 9.6"	HPA023544	Approved					NA	NA				"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 44: Endometrium - Transcription"			"HPA023544: AB_1847878"	"unprognostic (2.85e-2)"	"prognostic favorable (4.31e-6)"	"unprognostic (2.49e-2)"	"unprognostic (8.84e-3)"	"unprognostic (1.44e-2)"	"unprognostic (3.27e-2)"	"unprognostic (1.23e-1)"	"unprognostic (2.57e-2)"	"unprognostic (5.87e-2)"	"unprognostic (6.02e-3)"	"unprognostic (5.13e-2)"	"unprognostic (1.19e-1)"	"unprognostic (8.91e-3)"	"unprognostic (2.23e-1)"	"unprognostic (3.06e-2)"	"unprognostic (1.14e-2)"	"unprognostic (3.03e-1)"	1.5	14.1	0.7	1.0	1.0	0.2	4.5	12.4	1.2	44.5	0.0	1.0	0.6	3.0	50.0	108.5	14.0	3.3	3.3	1.0	0.3	0.7	0.4	70.1	0.3	0.3	0.3	1.8	0.5	5.2	1.3	1.5	0.6	13.8	0.3	0.6	18.7	13.0	0.4	81.7	0.7	0.4	0.1	0.3	64.3	1.6	0.4	1.1	70.4	0.0	14.7	11.1	42.0	3.2	8.3	0.1	0.5	0.0	0.0	0.0	0.6	0.1	0.0	0.0	0.0	0.1	0.3	0.0	0.2	0.0	0.0	64.4	0.0	6.1	0.0	0.8	0.4	0.0	0.9	0.1	0.0	0.0	0.3	0.0	30.5	0.0	1.9	0.1	0.0	0.1	0.0	0.4	0.0	0.0	0.0	0.1	0.0	0.3	0.0	1.2	0.1	0.0	0.0	36.3	0.8	1.5	0.0	0.0	0.0	0.1	0.0	0.2	0.1	0.1	0.2	0.0	0.0	0.1	0.2	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.7	1.0	12.4	1.2	1.0	0.3	0.3	0.3	0.6	0.1	0.4	3.2	0.9	83.3	168.6	4.2	4.5	11.1	14.3	22.8	11.4	21.3	4.7	2.8	2.4	8.6	32.5	3.7	8.4	5.3	7.6	2.5	0.0	3.8	0.7	67.1	9.4	3.8	21.7	2.7	5.1	5.4	0.6	5.1	17.9	88.5	8.2	7.9	7.9	1.5	1.2	6.7	3.9	4.0	16.2	3.1	43.5	0.3	3.4	3.3	16.0	1.0	3.2	3.5	33.0	9.5	10.6	4.7	4.0	3.8	0.1	9.5	6.8	0.5	64.9	4.4	0.0	8.5	4.7	11.5	7.5	36.4	18.0	3.7	4.5	0.4	5.6	30.0
DUOX2	"LNOX2, P138-TOX, P138(TOX), THOX2"	ENSG00000140279	"Dual oxidase 2"	Q9NRD8	15	45092650-45114172	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters"	"Hydrogen peroxide, Thyroid hormones biosynthesis"	"Oxidoreductase, Peroxidase"	"Congenital hypothyroidism, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"gallbladder: 290.2;thyroid gland: 75.7;urinary bladder: 92.8"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 159.3;Ductal cells: 225.2;Exocrine glandular cells: 125.5;Gastric mucus-secreting cells: 85.1;Pancreatic endocrine cells: 411.7;Urothelial cells: 110.4"	"Cancer enhanced"	"Detected in many"		"thyroid cancer: 60.0"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in single"	8	"HaCaT: 6.3"	"Region enhanced"	"Detected in single"		"basal ganglia: 1.2"	"Not detected"	"Not detected"									NA	NA				"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 16: Pancreatic endocrine cells - Mixed function"				"unprognostic (3.19e-1)"	"unprognostic (7.51e-2)"	"unprognostic (3.77e-2)"	"unprognostic (5.99e-2)"	"unprognostic (1.09e-1)"	"unprognostic (1.40e-2)"	"unprognostic (7.93e-2)"	"unprognostic (3.32e-1)"	"unprognostic (1.42e-1)"	"unprognostic (4.49e-2)"	"unprognostic (9.59e-3)"	"unprognostic (7.11e-2)"	"unprognostic (5.32e-5)"	"unprognostic (1.71e-1)"	"unprognostic (1.62e-2)"	"unprognostic (4.12e-2)"	"unprognostic (1.63e-2)"	0.5	1.4	0.0	21.5	0.1	0.0	0.6	0.1	0.3	2.8	0.0	11.6	1.5	0.2	3.1	21.5	0.5	290.2	0.8	0.1	0.1	0.7	0.8	2.5	0.1	0.2	0.6	0.5	1.2	0.2	0.1	0.0	0.1	11.8	5.5	0.0	4.6	1.9	0.0	4.9	8.3	2.7	0.1	0.0	42.3	1.4	0.1	0.0	75.7	0.0	4.2	92.8	21.7	0.3	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.3	0.0	0.0	6.3	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.7	0.0	0.1	0.1	0.2	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.3	0.1	0.1	0.2	0.6	0.1	0.1	0.1	0.3	0.1	48.1	36.9	0.0	3.0	1.9	5.2	11.7	1.8	0.4	0.6	0.6	1.9	54.3	31.5	0.0	0.0	0.1	0.0	159.3	0.0	225.2	0.6	1.0	0.5	5.6	1.2	0.0	0.1	125.5	0.0	5.1	85.1	3.5	32.8	0.1	0.4	0.1	0.1	0.0	0.1	10.1	4.1	0.0	0.4	0.3	0.3	3.9	0.0	0.0	5.2	0.2	0.0	0.0	0.1	411.7	45.5	0.0	0.8	4.5	2.9	0.0	43.4	0.3	0.0	0.2	2.7	0.9	1.0	3.6	1.8	0.0	4.6	0.1	34.7	110.4
DUS2	"DUS2L, FLJ20399, SMM1"	ENSG00000167264	"Dihydrouridine synthase 2"	Q9NX74	16	67987746-68079320	"Enzymes, Predicted intracellular proteins"	"tRNA processing"	"Oxidoreductase, RNA-binding"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 118.1;Late spermatids: 94.1;Spermatocytes: 53.1;Syncytiotrophoblasts: 61.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"HPA042560, HPA043528"	Enhanced		Enhanced	Cytosol		NA	NA			"Cluster 19: B-cells - Humoral immune response"	"Cluster 16: Immune cells - Immune response"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 25: Spermatids - Spermatogenesis"	Cytosol		"HPA042560: AB_10965170, HPA043528: AB_10959753"	"unprognostic (2.21e-1)"	"unprognostic (5.06e-2)"	"unprognostic (1.91e-1)"	"unprognostic (1.23e-2)"	"unprognostic (8.12e-2)"	"unprognostic (1.63e-2)"	"unprognostic (1.23e-2)"	"unprognostic (9.84e-2)"	"unprognostic (2.36e-1)"	"unprognostic (2.34e-1)"	"unprognostic (1.53e-1)"	"unprognostic (3.18e-1)"	"prognostic favorable (3.50e-5)"	"unprognostic (1.44e-2)"	"unprognostic (8.05e-2)"	"unprognostic (1.58e-1)"	"unprognostic (1.81e-1)"	5.8	6.8	5.2	12.6	5.8	9.6	5.8	6.8	7.5	6.1	4.6	8.6	5.7	5.3	4.9	12.2	5.1	5.5	6.1	5.3	6.1	5.9	9.2	6.8	18.8	6.8	5.8	4.8	4.4	7.5	4.9	9.9	6.6	5.4	8.4	5.3	5.9	5.0	9.6	10.8	10.4	7.9	5.0	15.9	6.4	27.5	6.4	7.6	5.4	8.9	20.2	7.0	7.4	7.8	17.1	25.5	11.0	17.1	8.8	14.8	20.4	16.1	15.6	33.4	23.7	27.5	29.9	39.7	14.3	17.0	9.8	22.8	26.6	28.5	25.5	6.1	16.0	13.4	15.6	20.6	14.9	15.1	18.4	14.5	21.9	27.5	26.8	12.8	21.3	29.9	16.1	6.5	16.0	24.9	16.0	22.5	12.2	16.9	13.5	26.8	12.5	28.3	18.4	11.8	13.0	11.3	31.8	12.3	7.1	14.1	25.1	8.4	11.7	14.8	13.3	12.9	13.6	18.4	24.5	36.6	10.6	19.7	8.8	12.1	29.2	89.9	9.5	25.8	9.2	56.9	6.5	10.3	21.9	48.4	9.4	8.5	27.8	21.3	37.7	8.6	13.5	17.2	5.2	5.8	6.8	7.5	5.3	6.1	6.8	5.8	6.6	5.0	6.4	7.8	2.5	9.6	4.6	6.8	17.1	2.7	2.0	12.8	4.6	3.9	2.4	2.2	2.6	4.3	6.2	7.3	8.4	29.2	6.0	5.7	5.9	10.4	118.1	1.7	3.5	5.3	4.2	3.0	7.2	5.4	17.3	3.8	4.6	2.6	7.0	7.2	9.3	7.9	13.4	15.2	8.0	5.5	6.1	11.9	2.3	94.1	3.7	6.2	3.6	2.8	13.5	4.5	9.2	5.5	7.3	9.5	3.6	7.9	7.7	3.4	4.2	10.8	4.1	2.9	6.6	3.4	4.7	53.1	15.0	5.2	2.6	61.4	4.2	10.0	6.0	2.1
EGLN1	"C1orf12, HIFPH2, PHD2, SM-20, ZMYND6"	ENSG00000135766	"Egl-9 family hypoxia inducible factor 1"	Q9GZT9	1	231363751-231422287	"Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"	"Congenital erythrocytosis, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 190.7"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in many"	7	"neutrophil: 29.1"	"Lineage enriched"	"Detected in many"	15	"granulocytes: 29.1"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA022129	Approved					NA	NA			"Cluster 50: Neutrophils - Cellular senescence"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"			"HPA022129: AB_1848046"	"unprognostic (4.20e-1)"	"prognostic unfavorable (2.99e-7)"	"unprognostic (8.86e-2)"	"unprognostic (1.26e-1)"	"unprognostic (3.87e-1)"	"unprognostic (1.67e-1)"	"unprognostic (1.20e-1)"	"unprognostic (3.87e-3)"	"unprognostic (1.91e-1)"	"unprognostic (3.99e-1)"	"unprognostic (6.63e-2)"	"unprognostic (9.71e-2)"	"unprognostic (3.82e-2)"	"unprognostic (1.23e-1)"	"unprognostic (1.55e-1)"	"unprognostic (5.65e-2)"	"unprognostic (1.81e-2)"	32.8	35.6	37.5	18.1	40.8	20.0	23.9	38.8	43.2	26.3	31.6	30.0	34.0	30.8	24.5	33.6	24.2	28.2	58.7	39.9	37.2	38.8	56.5	19.1	21.1	41.6	39.0	37.5	40.0	39.0	9.3	42.6	36.8	23.8	26.1	49.9	22.0	30.3	190.7	48.6	35.5	27.6	40.9	27.6	19.1	17.1	43.4	16.7	25.5	153.4	21.3	27.0	12.0	40.9	54.2	59.9	17.5	33.7	44.8	29.4	15.8	22.7	42.2	36.3	49.4	41.3	48.0	15.5	41.7	42.4	31.7	25.1	26.8	30.1	61.0	18.6	42.5	6.7	23.5	37.7	31.5	38.5	8.1	25.4	27.5	24.9	34.2	58.6	49.3	18.5	33.9	37.9	38.3	12.2	8.9	14.4	18.4	33.4	21.0	20.0	21.7	22.7	48.0	23.4	15.9	45.3	32.9	41.4	83.1	11.2	22.4	112.8	54.3	44.3	20.8	40.5	47.2	65.7	46.4	14.7	60.4	14.0	59.4	4.2	0.5	3.1	1.2	1.0	0.7	0.7	0.9	0.8	0.8	0.7	1.0	1.8	29.1	1.6	1.8	0.7	0.5	0.4	37.5	40.8	38.8	43.2	39.9	37.2	41.6	39.0	36.8	40.9	43.4	40.9	64.7	19.2	23.2	36.6	19.8	58.5	15.0	10.7	33.0	32.3	19.4	13.3	111.9	67.2	11.6	18.4	37.5	16.2	16.6	57.6	35.2	37.8	1.2	18.5	20.2	60.6	12.7	8.2	43.9	36.2	34.2	25.9	15.3	21.2	10.1	55.6	28.9	70.6	16.9	62.2	52.6	24.6	16.2	24.1	45.3	5.0	16.1	29.8	26.6	44.0	19.0	56.9	12.3	46.3	48.3	36.6	30.9	23.0	23.9	15.1	43.2	52.3	13.5	44.0	19.7	36.4	36.6	13.1	20.9	24.9	57.5	10.4	24.9	16.0	23.5	21.3
EGLN2	"HIFPH1, PHD1"	ENSG00000269858	"Egl-9 family hypoxia inducible factor 2"	Q96KS0	19	40798996-40808434	"Enzymes, Plasma proteins, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 269.1;Late spermatids: 740.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA056649			Supported	Nucleoplasm		NA	NA			"Cluster 5: Granulocytes - Unknown function"	"Cluster 78: Testis - Spermatogenesis"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 25: Spermatids - Spermatogenesis"	Nucleoplasm		"HPA056649: AB_2683203"	"unprognostic (1.11e-2)"	"prognostic favorable (2.88e-4)"	"unprognostic (9.40e-3)"	"unprognostic (6.01e-2)"	"unprognostic (6.03e-2)"	"unprognostic (6.47e-3)"	"unprognostic (1.51e-2)"	"unprognostic (4.74e-2)"	"unprognostic (1.67e-1)"	"unprognostic (1.95e-1)"	"prognostic favorable (4.81e-4)"	"unprognostic (7.10e-2)"	"unprognostic (7.48e-2)"	"unprognostic (1.69e-1)"	"unprognostic (1.35e-1)"	"unprognostic (9.99e-2)"	"unprognostic (1.38e-3)"	57.6	58.5	99.3	50.0	99.8	52.1	47.6	95.1	140.9	70.0	79.6	65.4	34.3	53.9	31.5	40.2	45.5	39.1	67.8	103.4	96.2	54.2	57.7	74.3	62.4	97.3	99.3	59.0	36.6	27.7	44.5	48.3	97.7	59.9	28.5	16.6	39.2	45.1	40.0	27.4	46.7	40.9	90.5	116.8	47.6	232.1	99.9	41.9	55.8	40.8	44.1	57.9	57.9	98.1	46.5	123.4	55.9	54.4	71.1	51.5	36.5	49.4	41.1	68.9	75.4	102.8	45.7	41.1	41.1	59.3	62.5	29.3	70.8	56.3	36.4	51.7	40.5	54.8	76.4	39.4	76.1	42.7	71.6	63.9	58.5	65.8	37.4	43.3	86.0	44.3	79.3	37.3	73.4	32.9	78.9	70.2	48.7	72.4	42.6	72.7	27.7	27.8	74.0	70.2	51.4	46.9	80.9	62.9	67.2	47.2	83.4	114.0	80.5	85.9	61.7	35.7	59.5	18.7	29.6	75.6	63.0	61.4	65.5	93.2	72.5	190.5	85.8	83.4	91.1	85.2	101.7	90.3	62.6	90.0	105.2	89.6	261.6	61.4	82.3	45.5	100.2	110.5	99.3	99.8	95.1	140.9	103.4	96.2	97.3	99.3	97.7	90.5	99.9	98.1	2.8	22.4	16.8	0.0	43.9	48.8	55.2	33.8	17.6	40.5	3.3	0.8	22.2	31.5	30.7	3.7	14.6	58.1	19.0	83.0	0.0	15.8	269.1	0.9	1.5	49.9	44.9	30.7	0.0	10.1	26.5	27.6	23.9	1.2	17.2	0.8	72.8	33.7	66.7	21.9	0.0	33.9	48.8	39.8	62.4	740.8	63.0	26.3	40.9	0.0	38.5	24.4	60.8	0.0	0.0	14.0	71.0	52.3	8.7	67.6	54.9	1.4	23.0	17.8	39.5	14.6	17.2	159.4	52.5	14.2	38.4	132.6	33.2	2.1	43.7	69.8
EGLN3	"HIFPH3, PHD3"	ENSG00000129521	"Egl-9 family hypoxia inducible factor 3"	Q9H6Z9	14	33924227-34462774	"Enzymes, Predicted intracellular proteins"	"Apoptosis, DNA damage"	"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 110.3;skin 1: 118.2"	"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 213.7;Cardiomyocytes: 105.8;Distal enterocytes: 135.5;Extravillous trophoblasts: 115.9;Suprabasal keratinocytes: 231.6"	"Cancer enhanced"	"Detected in all"		"renal cancer: 50.9"	"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in some"	10	"plasmacytoid DC: 25.5"	"Lineage enriched"	"Detected in many"	14	"dendritic cells: 25.5"	"Cell line enhanced"	"Detected in many"		"RH-30: 44.6;RPTEC TERT1: 38.2;RT4: 122.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA064895			Supported	Cytosol		NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 15: RT4 - Unknown function"	"Cluster 65: Plasmacytoid DCs - Unknown function"	Cytosol		"HPA064895: AB_2685384"	"unprognostic (3.58e-2)"	"unprognostic (4.76e-3)"	"unprognostic (1.75e-1)"	"unprognostic (8.87e-2)"	"unprognostic (6.88e-2)"	"unprognostic (1.38e-2)"	"prognostic unfavorable (2.14e-5)"	"unprognostic (1.39e-3)"	"unprognostic (3.44e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.93e-2)"	"unprognostic (2.90e-1)"	"prognostic unfavorable (2.50e-4)"	"unprognostic (1.37e-1)"	"unprognostic (5.21e-2)"	"unprognostic (4.71e-2)"	"unprognostic (6.30e-2)"	14.6	0.8	32.9	9.4	40.9	0.3	10.0	38.2	37.5	12.3	15.4	25.9	35.7	10.0	4.4	27.0	9.4	13.8	110.3	29.7	38.9	16.3	4.9	8.3	5.7	34.3	37.5	2.1	4.3	0.3	3.4	25.4	32.2	9.1	20.0	15.2	11.2	12.0	20.8	118.2	40.9	11.7	31.9	4.9	37.7	1.1	42.9	4.9	2.8	6.4	9.8	51.3	20.8	36.1	31.1	8.0	0.9	32.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	5.3	8.2	0.0	10.0	0.1	0.9	0.9	15.0	29.4	0.0	3.1	8.0	8.3	20.5	1.0	0.0	0.0	0.4	4.0	14.5	0.0	0.1	0.0	0.0	2.3	16.9	0.0	0.4	2.7	0.7	0.1	24.3	26.7	2.8	0.0	44.6	11.1	38.2	122.9	6.2	7.0	2.0	11.8	3.2	18.2	12.0	0.1	0.0	0.2	3.2	0.0	1.8	0.4	6.7	0.1	7.2	0.0	0.5	0.0	0.0	1.8	0.1	0.0	0.0	0.0	1.2	0.9	2.6	0.0	0.1	0.1	0.1	1.1	0.0	25.5	0.0	0.9	32.9	40.9	38.2	37.5	29.7	38.9	34.3	37.5	32.2	31.9	42.9	36.1	6.0	0.0	0.6	36.2	1.6	213.7	49.0	56.6	3.4	11.6	16.0	17.0	105.8	4.3	24.8	9.2	2.1	11.4	16.0	135.5	9.8	15.6	1.8	42.3	8.5	25.1	16.2	0.4	1.0	6.9	115.9	16.8	74.9	17.2	1.3	0.1	12.5	0.3	3.1	1.7	4.3	31.6	12.2	1.9	62.8	4.9	2.5	10.8	40.9	0.0	0.9	11.6	0.0	6.6	54.2	46.6	41.9	0.7	0.4	17.4	59.7	20.5	37.2	2.4	0.0	17.7	9.4	1.7	0.3	4.1	231.6	103.0	4.5	1.2	14.1	25.7
EHHADH	ECHD	ENSG00000113790	"Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase"	Q08426	3	185190624-185281990	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in all"	11	"kidney: 144.3;liver: 344.5"	"Group enriched"	"Detected in many"	10	"Hepatocytes: 289.0;Proximal tubular cells: 147.1"	"Group enriched"	"Detected in all"	7	"liver cancer: 42.2;renal cancer: 25.4"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA036401, HPA042021"	Enhanced					NA	NA			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA036401: AB_10670165, HPA042021: AB_2677801"	"unprognostic (1.20e-1)"	"unprognostic (5.99e-2)"	"unprognostic (2.17e-3)"	"unprognostic (2.69e-2)"	"unprognostic (6.82e-2)"	"unprognostic (1.48e-1)"	"unprognostic (4.79e-3)"	"unprognostic (1.25e-1)"	"unprognostic (1.73e-1)"	"unprognostic (3.89e-2)"	"unprognostic (3.19e-3)"	"unprognostic (1.87e-1)"	"prognostic favorable (1.28e-5)"	"unprognostic (1.93e-1)"	"unprognostic (1.53e-1)"	"unprognostic (2.96e-2)"	"unprognostic (2.80e-1)"	10.8	4.3	2.1	3.0	2.9	1.2	4.1	3.9	2.7	3.5	9.2	14.2	21.5	2.8	3.5	5.5	3.6	4.4	10.7	2.1	3.1	144.3	344.5	4.3	2.1	3.2	4.1	2.6	9.9	7.8	1.5	3.2	3.0	6.3	10.8	1.6	5.7	2.2	1.7	4.5	12.9	3.7	2.5	3.7	10.4	2.7	3.1	2.1	6.5	5.6	2.8	3.6	2.1	2.8	12.3	5.0	1.4	0.0	7.3	6.1	1.5	5.7	1.8	3.7	4.1	21.9	7.5	0.0	22.1	5.7	1.4	5.8	0.0	4.8	7.6	16.2	5.2	8.6	1.3	22.5	4.7	1.0	0.2	8.7	6.0	3.7	3.4	5.0	5.5	0.0	5.7	6.1	7.2	6.4	0.2	5.1	3.0	4.3	6.3	0.0	9.9	0.5	15.4	6.8	4.4	6.4	11.2	6.4	10.5	12.1	23.7	10.1	2.6	2.4	3.6	1.9	0.5	1.7	5.6	0.5	0.8	3.9	4.0	0.1	0.9	0.0	0.6	0.8	0.4	0.5	0.4	0.9	2.4	0.0	0.6	1.0	0.0	1.2	0.8	1.0	0.6	0.4	2.1	2.9	3.9	2.7	2.1	3.1	3.2	4.1	3.0	2.5	3.1	2.8	4.9	16.0	10.9	20.9	4.5	1.5	1.4	1.9	1.2	0.7	3.2	2.3	19.2	17.2	3.9	20.2	4.2	8.9	0.4	17.8	19.6	2.1	0.2	6.5	5.1	3.9	7.7	9.7	4.9	6.8	2.9	1.6	8.6	3.1	0.0	6.1	13.6	289.0	4.4	0.0	5.7	12.8	0.0	10.5	1.0	0.7	0.6	2.7	3.6	4.7	9.4	1.9	0.0	3.5	8.0	3.7	9.3	0.4	0.8	2.5	15.0	147.1	4.0	1.2	0.0	1.1	2.4	3.7	4.2	4.9	0.4	1.4	2.2	3.6	10.8	1.8
EPX	"EPO, EPP, EPX-PEN"	ENSG00000121053	"Eosinophil peroxidase"	P11678	17	58192726-58205174	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Hydrogen peroxide"	"Oxidoreductase, Peroxidase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	17	"bone marrow: 33.7"	"Cell type enhanced"	"Detected in some"		"Excitatory neurons: 1.5;Inhibitory neurons: 1.2;Microglial cells: 1.0;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 1.0"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Immune cell enriched"	"Detected in single"	23	"eosinophil: 2.2"	"Lineage enriched"	"Detected in single"	23	"granulocytes: 2.2"	"Cell line enriched"	"Detected in some"	68	"NB-4: 248.2"	"Low region specificity"	"Detected in some"			"Not detected"	"Not detected"			HPA076792	Enhanced					NA	NA			"Cluster 49: Eosinophils - Unknown function"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 24: NB-4 - Immune response"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"			"HPA076792: "	"unprognostic (5.67e-2)"	"unprognostic (1.73e-2)"	"unprognostic (3.36e-2)"	"unprognostic (3.30e-1)"	"unprognostic (2.18e-1)"	"unprognostic (1.34e-3)"	"unprognostic (4.83e-1)"	"unprognostic (3.16e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.52e-2)"	"unprognostic (1.71e-4)"	"unprognostic (7.38e-2)"	"unprognostic (1.64e-1)"	"unprognostic (2.02e-1)"	"unprognostic (5.43e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.73e-1)"	0.0	0.1	0.0	0.2	0.2	33.7	0.0	0.3	0.1	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.1	0.2	0.4	0.4	0.0	0.0	0.2	0.0	0.0	0.1	0.2	0.0	0.0	0.0	0.5	0.3	0.0	0.1	0.5	0.1	0.0	0.0	1.3	0.1	0.1	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.1	0.0	0.0	0.0	3.6	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.1	0.2	248.2	0.0	0.0	0.0	0.3	0.1	0.1	0.0	0.0	0.5	0.1	0.0	0.0	0.1	0.1	0.2	2.9	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.4	0.0	0.0	0.0	2.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	2.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
ETFDH	ETFQO	ENSG00000171503	"Electron transfer flavoprotein dehydrogenase"	Q16134	4	158672125-158709623	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Electron transport, Transport"	Oxidoreductase	"Disease variant, FDA approved drug targets, Glutaricaciduria"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 196.4;tongue: 186.9"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 146.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA041978	Enhanced					NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 54: Cardiomyocytes - Muscle contraction"			"HPA041978: AB_10795605"	"unprognostic (7.19e-2)"	"unprognostic (2.28e-1)"	"unprognostic (2.90e-2)"	"unprognostic (5.92e-3)"	"unprognostic (1.91e-1)"	"unprognostic (8.45e-2)"	"unprognostic (1.23e-3)"	"unprognostic (7.17e-2)"	"unprognostic (2.01e-1)"	"unprognostic (4.55e-2)"	"unprognostic (1.71e-2)"	"unprognostic (5.76e-2)"	"prognostic favorable (5.76e-10)"	"unprognostic (2.51e-1)"	"unprognostic (2.07e-1)"	"unprognostic (8.85e-3)"	"unprognostic (1.74e-1)"	34.6	38.0	13.3	10.7	14.8	9.4	16.0	13.9	15.1	10.2	25.5	32.6	63.7	10.4	8.4	25.0	9.3	11.1	93.3	12.8	14.5	46.5	196.4	9.2	8.7	12.3	13.8	10.8	20.4	32.8	9.8	13.0	12.8	13.7	26.9	15.8	21.8	13.2	111.0	18.7	51.4	14.8	12.5	9.5	26.9	11.2	15.0	9.4	13.2	186.9	14.3	12.9	12.8	15.1	13.2	9.2	12.2	21.4	47.2	28.8	6.6	21.3	19.4	13.9	14.3	3.7	24.6	27.8	4.6	24.1	15.8	13.8	22.1	20.9	19.2	51.5	20.3	26.5	17.3	8.0	20.8	24.0	23.4	26.5	23.8	15.8	12.8	20.8	27.3	20.7	15.6	53.8	22.2	14.7	22.7	11.0	5.0	33.2	19.4	18.4	4.3	21.9	21.2	10.6	18.7	8.0	21.0	39.5	21.8	10.0	30.4	17.6	13.6	11.9	6.7	18.5	12.2	31.3	42.1	20.3	24.6	19.2	13.5	3.7	21.5	41.5	10.1	22.6	12.7	10.3	9.8	10.4	18.3	9.6	11.6	9.9	7.8	10.5	20.9	13.1	16.1	9.5	13.3	14.8	13.9	15.1	12.8	14.5	12.3	13.8	12.8	12.5	15.0	15.1	18.1	12.8	10.3	55.2	18.5	33.0	46.0	27.2	29.6	29.2	12.6	13.8	146.6	14.3	22.8	18.4	64.6	24.9	18.0	34.4	29.4	14.4	4.2	12.5	12.5	17.7	18.0	30.7	43.2	11.7	9.9	23.9	44.4	14.2	5.1	19.2	12.8	85.7	13.4	25.2	71.9	22.5	30.5	14.4	15.8	4.7	23.0	13.3	8.8	15.0	12.2	13.9	10.3	55.8	58.0	11.7	29.4	23.7	30.1	21.3	58.3	26.8	13.1	43.9	32.9	27.4	30.4	43.2	29.8	32.7	36.9	43.0	19.7	15.7	26.2	38.7
ETHE1	"HSCO, YF13H12"	ENSG00000105755	"ETHE1 persulfide dioxygenase"	O95571	19	43506719-43527230	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"intestine: 256.1"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 1037.7;Paneth cells: 788.4;Proximal enterocytes: 376.3;Undifferentiated cells: 447.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 222.6;OE19: 360.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA028360, HPA029028, HPA029029"	Enhanced		Enhanced	Mitochondria		No	No			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 37: Intestine - Unknown function"	"Cluster 21: OE19 - Mitochondria"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Mitochondria		"HPA028360: AB_10599297, HPA029028: AB_10602092, HPA029029: AB_10601998"	"unprognostic (8.04e-2)"	"unprognostic (3.33e-1)"	"unprognostic (1.50e-2)"	"unprognostic (2.45e-1)"	"unprognostic (8.34e-2)"	"unprognostic (1.25e-2)"	"unprognostic (2.58e-1)"	"prognostic unfavorable (9.58e-4)"	"unprognostic (7.75e-2)"	"unprognostic (2.28e-1)"	"unprognostic (5.47e-2)"	"unprognostic (3.24e-1)"	"unprognostic (1.01e-1)"	"unprognostic (5.27e-2)"	"unprognostic (1.75e-1)"	"unprognostic (9.72e-3)"	"unprognostic (2.73e-2)"	24.4	27.9	16.1	34.8	17.0	45.8	26.7	16.5	17.3	28.7	15.8	256.1	85.5	18.3	29.8	81.0	20.6	21.0	18.8	15.6	17.4	40.4	52.7	30.5	23.4	17.3	17.2	13.5	28.9	16.1	19.1	26.3	16.6	27.1	226.6	3.2	40.1	18.5	22.8	27.2	77.0	35.6	17.1	27.8	37.8	3.0	18.2	19.8	24.1	21.9	41.7	34.4	39.1	17.2	54.1	68.9	14.1	49.6	75.1	50.9	5.5	82.1	222.6	69.8	71.1	21.1	54.3	0.2	60.0	79.8	22.2	42.9	20.6	123.4	19.6	26.2	6.2	13.8	29.7	59.2	34.0	19.3	18.4	52.2	95.1	26.9	76.0	92.2	52.0	49.8	9.0	87.6	35.1	35.7	22.2	18.9	3.8	360.5	32.9	26.6	6.1	12.0	153.0	110.9	0.2	16.6	20.8	74.8	50.6	23.6	22.4	34.3	41.6	10.9	46.9	13.1	15.3	23.1	20.2	1.4	48.4	83.8	57.7	24.2	63.3	1.6	41.1	34.5	48.3	20.5	47.6	39.4	95.8	7.5	36.4	35.0	2.1	29.3	22.8	17.9	50.4	40.2	16.1	17.0	16.5	17.3	15.6	17.4	17.3	17.2	16.6	17.1	18.2	17.2	32.0	22.4	23.4	3.9	25.5	34.5	82.2	242.5	57.5	9.8	85.8	95.2	9.8	47.1	84.5	55.2	0.0	191.6	38.0	1037.7	54.8	71.7	0.9	31.0	41.2	44.9	63.7	17.4	6.2	63.6	95.7	42.1	53.5	68.2	38.0	12.6	42.1	89.2	115.1	5.0	6.8	324.2	79.3	105.0	78.5	2.1	17.7	74.6	80.0	3.7	78.5	11.7	63.8	4.0	5.6	102.7	788.4	16.1	34.9	75.0	376.3	136.4	23.1	5.8	19.7	32.0	45.1	2.1	6.2	82.8	23.2	92.5	50.4	15.8	447.5	146.5
FADS1	"D5D, FADS6, FADSD5, LLCDL1, TU12"	ENSG00000149485	"Fatty acid desaturase 1"	O60427	11	61799627-61829318	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport"	Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Rod photoreceptor cells: 91.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"ASC TERT1: 521.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA042705	Approved					NA	NA			"Cluster 25: Monocytes - Inflammatory response"	"Cluster 73: Brain - Neuropeptide signaling"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 65: Plasmacytoid DCs - Unknown function"			"HPA042705: AB_10795709"	"unprognostic (8.28e-2)"	"unprognostic (3.54e-1)"	"unprognostic (1.29e-1)"	"unprognostic (1.99e-1)"	"unprognostic (8.17e-3)"	"unprognostic (1.40e-1)"	"unprognostic (1.99e-2)"	"unprognostic (3.23e-3)"	"unprognostic (7.88e-2)"	"unprognostic (1.94e-2)"	"unprognostic (4.10e-2)"	"unprognostic (2.00e-1)"	"prognostic unfavorable (1.95e-9)"	"unprognostic (2.29e-2)"	"unprognostic (3.59e-2)"	"prognostic unfavorable (2.79e-4)"	"prognostic unfavorable (1.33e-4)"	26.2	67.7	43.1	19.8	39.2	9.7	13.6	38.4	40.7	19.6	70.7	9.5	5.5	21.3	6.6	5.2	17.4	14.5	22.6	39.3	58.5	9.7	52.8	20.3	9.8	57.9	62.1	27.5	10.0	27.2	21.3	21.1	52.2	19.6	4.9	35.1	6.4	15.8	17.5	15.5	6.7	20.5	46.4	8.0	9.4	11.9	68.7	8.1	6.0	7.8	9.2	12.7	10.2	56.0	66.3	170.1	159.1	41.1	313.2	521.2	46.4	42.0	204.5	69.9	118.9	53.3	143.2	2.3	43.4	60.5	177.2	84.7	130.8	114.1	51.7	12.2	18.4	107.9	191.2	98.9	169.1	23.4	10.4	238.1	38.3	154.7	74.7	73.8	64.1	104.7	59.9	118.6	70.1	18.6	78.6	23.6	94.2	5.5	63.0	85.4	162.5	231.2	81.5	29.0	80.7	89.6	106.7	1.7	90.0	58.4	38.6	98.6	62.1	71.8	70.8	74.2	50.6	112.9	111.3	55.4	42.6	108.9	61.4	7.5	33.2	6.2	12.1	40.4	2.6	2.5	4.0	4.9	28.0	8.7	2.3	5.4	2.6	6.9	17.4	23.6	2.9	15.7	43.1	39.2	38.4	40.7	39.3	58.5	57.9	62.1	52.2	46.4	68.7	56.0	10.3	6.4	77.9	28.7	3.2	2.7	2.5	48.5	1.2	78.9	2.6	3.7	30.4	8.6	25.3	12.9	27.1	9.5	12.4	0.9	0.0	15.2	8.7	4.9	30.7	16.6	9.7	46.3	9.4	33.4	50.0	34.9	6.1	7.8	37.9	65.3	9.3	74.5	37.2	69.0	14.7	0.6	16.2	21.7	21.0	16.4	29.8	27.6	32.0	12.2	32.0	70.5	6.2	13.6	27.4	7.6	0.0	21.4	2.1	6.4	0.1	1.1	8.0	91.9	0.0	40.3	31.9	6.5	17.5	2.3	1.4	9.3	5.5	75.2	1.4	1.6
FADS2	"D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13"	ENSG00000134824	"Fatty acid desaturase 2"	O95864	11	61792980-61867354	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport"	Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adrenal gland: 364.1"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 69.9;Endometrial stromal cells: 57.7;Hepatocytes: 55.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"ASC TERT1: 1141.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA006741	Approved					NA	NA			"Cluster 40: NK-cells - Unknown function"	"Cluster 73: Brain - Neuropeptide signaling"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 33: Fibroblasts - ECM organization"			"HPA006741: AB_1078796"	"unprognostic (2.37e-2)"	"unprognostic (1.02e-1)"	"unprognostic (8.34e-2)"	"unprognostic (4.33e-3)"	"unprognostic (4.63e-2)"	"unprognostic (2.42e-2)"	"unprognostic (4.51e-2)"	"unprognostic (4.35e-3)"	"unprognostic (2.01e-1)"	"unprognostic (4.21e-2)"	"unprognostic (8.95e-3)"	"unprognostic (7.80e-2)"	"prognostic unfavorable (1.00e-7)"	"unprognostic (6.19e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.41e-2)"	"prognostic unfavorable (3.42e-4)"	23.7	364.1	140.2	34.7	126.7	28.0	59.6	128.5	135.0	68.0	157.0	24.2	31.9	86.3	27.7	10.6	34.6	20.2	27.7	131.8	164.8	20.3	126.7	33.4	16.5	175.1	186.2	29.1	9.8	80.0	50.8	40.6	155.1	97.7	13.2	41.5	24.3	188.7	12.3	131.6	15.9	125.3	152.0	11.5	14.1	27.8	222.9	34.1	10.4	8.8	31.2	24.6	27.9	134.2	14.6	492.6	655.8	345.0	551.3	1141.8	167.2	86.3	658.3	109.0	288.2	31.4	149.6	3.8	11.4	172.3	167.8	15.7	436.4	709.5	52.7	6.9	11.8	297.9	106.5	72.0	421.9	18.9	15.9	430.9	25.8	383.4	39.1	170.3	324.4	254.4	17.9	212.1	52.0	13.5	166.4	104.7	291.5	0.7	150.1	206.1	13.9	663.1	392.1	4.4	197.4	260.8	49.9	1.4	23.5	164.0	21.5	197.7	139.2	14.0	120.5	9.8	13.1	115.7	110.3	39.7	13.0	96.3	131.2	4.4	6.0	6.9	8.5	8.7	2.0	1.4	3.1	4.6	10.1	3.7	1.8	3.8	2.8	6.6	7.4	13.0	2.9	4.9	140.2	126.7	128.5	135.0	131.8	164.8	175.1	186.2	155.1	152.0	222.9	134.2	3.2	9.6	18.8	69.9	2.0	1.7	1.3	26.9	0.0	9.1	4.7	3.0	4.2	1.5	15.1	3.7	4.2	1.7	5.2	0.5	0.0	6.9	2.2	4.7	57.7	12.2	5.4	26.7	7.4	17.8	22.0	21.0	5.1	9.5	5.1	28.3	2.5	55.8	20.5	5.0	7.7	0.2	22.4	7.2	3.1	5.3	25.7	7.0	8.8	15.0	20.7	32.1	8.2	38.7	11.9	5.1	0.0	23.7	1.4	16.9	0.1	0.7	5.4	13.2	0.0	23.8	29.5	1.3	0.5	1.2	0.6	3.1	2.5	28.3	2.0	0.9
FAR1	"FLJ22728, MLSTD2, SDR10E1"	ENSG00000197601	"Fatty acyl-CoA reductase 1"	Q8WVX9	11	13668668-13732346	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism"	Oxidoreductase	"Cataract, Disease variant, Epilepsy, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Oligodendrocytes: 437.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA017322	Approved		Supported	Peroxisomes		NA	NA			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 15: RT4 - Unknown function"	"Cluster 25: Spermatids - Spermatogenesis"	Peroxisomes		"HPA017322: AB_1848424"	"unprognostic (3.96e-2)"	"unprognostic (1.92e-1)"	"prognostic favorable (2.27e-4)"	"unprognostic (1.38e-1)"	"unprognostic (1.34e-1)"	"unprognostic (4.62e-2)"	"unprognostic (3.66e-1)"	"unprognostic (3.30e-1)"	"unprognostic (2.79e-1)"	"unprognostic (3.60e-2)"	"unprognostic (2.59e-2)"	"unprognostic (1.84e-2)"	"unprognostic (2.97e-2)"	"unprognostic (2.52e-1)"	"unprognostic (2.22e-1)"	"unprognostic (2.22e-1)"	"unprognostic (2.37e-3)"	21.1	16.2	19.3	23.0	36.0	74.9	20.6	34.3	31.5	23.8	24.5	32.9	38.7	24.7	24.9	50.9	17.7	13.7	20.0	22.6	29.7	14.0	5.0	20.2	20.5	48.4	29.9	19.9	21.3	29.1	15.6	24.6	44.1	20.5	37.6	32.6	18.2	15.4	15.2	12.2	21.1	30.7	37.3	20.5	62.0	20.8	32.1	16.5	19.8	18.6	23.9	28.4	30.0	94.8	79.5	50.6	49.1	38.4	45.9	52.6	26.7	69.2	27.6	50.0	52.7	53.5	66.4	100.9	30.2	55.5	74.3	84.3	73.2	69.9	76.1	30.0	59.4	43.4	44.8	0.2	44.1	87.9	33.7	40.2	70.3	36.2	107.7	36.9	49.6	50.2	68.9	29.3	41.5	39.9	65.5	26.3	25.8	100.1	72.6	56.9	62.6	28.4	48.4	126.4	37.7	27.3	65.5	61.6	34.4	56.2	37.8	54.1	62.1	68.5	58.2	63.7	58.4	16.4	59.6	84.7	43.4	26.4	42.4	10.4	24.9	28.0	7.7	21.3	5.4	3.5	3.7	6.6	28.5	5.5	3.3	5.5	38.9	9.1	18.2	4.4	5.3	7.7	19.3	36.0	34.3	31.5	22.6	29.7	48.4	29.9	44.1	37.3	32.1	94.8	38.6	35.3	21.1	80.0	24.2	32.2	24.2	21.5	41.5	46.0	27.6	20.3	24.1	5.7	26.2	22.0	41.7	25.7	40.2	59.8	5.9	12.8	100.8	21.1	36.5	31.4	36.0	38.5	146.0	25.9	18.5	26.8	114.7	26.2	38.7	23.3	29.6	2.5	33.9	47.1	113.5	28.8	26.4	53.5	57.0	181.3	26.8	48.8	35.6	71.2	54.8	20.6	20.6	93.5	437.2	29.3	43.4	25.6	36.1	30.8	23.3	8.7	18.7	50.4	26.3	29.3	29.3	41.6	32.3	116.9	19.9	9.9	25.8	17.0	47.7	42.0
FAR2	"FLJ10462, MLSTD1, SDR10E2"	ENSG00000064763	"Fatty acyl-CoA reductase 2"	Q96K12	12	29149103-29340980	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"epididymis: 36.2;intestine: 34.5"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 114.3;Inhibitory neurons: 172.1;Microglial cells: 63.7;Syncytiotrophoblasts: 193.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"eosinophil: 50.0"	"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"HEL: 76.2;HUVEC TERT2: 84.0;NB-4: 74.2;SK-BR-3: 89.6;TIME: 68.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA015884	Approved		Approved	"Nucleoli,Golgi apparatus"		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 37: Intestine - Unknown function"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	"Golgi apparatus"	Nucleoli	"HPA015884: AB_1853998"	"unprognostic (6.32e-2)"	"unprognostic (2.40e-2)"	"unprognostic (1.50e-3)"	"unprognostic (3.33e-3)"	"unprognostic (2.41e-1)"	"unprognostic (4.13e-3)"	"unprognostic (4.30e-2)"	"unprognostic (1.18e-1)"	"unprognostic (3.11e-2)"	"unprognostic (6.37e-2)"	"unprognostic (5.70e-3)"	"unprognostic (1.92e-1)"	"prognostic unfavorable (4.93e-4)"	"unprognostic (2.10e-1)"	"unprognostic (2.23e-1)"	"unprognostic (1.33e-1)"	"unprognostic (5.22e-3)"	8.3	9.0	4.1	9.3	8.3	17.1	9.3	1.2	8.5	4.3	0.0	34.5	17.6	5.6	36.2	7.4	3.6	5.2	6.6	6.2	9.2	5.0	3.8	11.3	7.9	1.2	2.9	2.3	3.2	1.3	2.4	18.1	1.3	2.6	28.2	9.4	4.4	1.9	6.3	9.0	19.2	7.6	1.4	12.2	4.9	9.2	5.2	7.0	4.4	2.6	3.0	6.5	3.7	4.9	2.5	4.9	4.9	1.2	6.8	26.9	2.1	21.3	24.7	5.8	5.4	8.2	28.0	3.7	5.4	3.4	4.3	1.5	13.4	0.2	1.4	1.8	32.2	76.2	10.7	2.7	14.7	30.0	24.0	7.5	0.2	8.7	11.0	14.3	84.0	2.9	6.6	2.7	0.9	0.8	19.9	74.2	19.3	1.6	54.5	16.1	7.9	3.1	25.7	7.2	8.6	7.9	4.8	89.6	37.8	9.7	4.1	28.2	68.2	15.6	4.6	5.6	9.3	4.4	4.9	1.8	24.5	38.5	13.7	3.8	22.8	50.0	5.0	13.9	3.4	2.0	8.3	6.2	8.1	1.8	2.9	3.2	41.0	4.0	8.0	3.1	16.1	9.6	4.1	8.3	1.2	8.5	6.2	9.2	1.2	2.9	1.3	1.4	5.2	4.9	9.1	0.0	3.3	7.8	0.6	1.3	0.1	0.2	0.6	2.0	1.4	0.8	12.1	0.0	1.4	0.0	0.0	16.0	1.1	35.7	0.0	0.1	31.5	0.4	2.9	11.9	7.2	4.6	114.3	0.2	19.6	4.8	5.6	0.4	10.8	0.0	9.7	0.0	19.3	5.0	172.1	21.8	0.0	22.2	3.7	6.4	1.2	12.2	16.0	63.7	6.9	0.5	1.0	24.6	6.9	3.3	36.8	0.4	8.0	0.4	15.1	0.4	3.2	1.2	0.0	4.2	3.6	16.6	1.0	0.3	0.3	193.9	4.2	0.9	23.7	0.3
FASN	"FAS, SDR27X1"	ENSG00000169710	"Fatty acid synthase"	P49327	17	82078338-82098294	"Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	"Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 372.8;breast: 271.6"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 126.0;Breast glandular cells: 442.9;Breast myoepithelial cells: 165.4;Hepatocytes: 244.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in all"		"SK-BR-3: 1109.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB005192, HPA006461, CAB015417, HPA056108"	Enhanced		Enhanced	"Plasma membrane,Cytosol"		No	No		3400000		"Cluster 57: Non-specific - Angiogenesis"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 30: Mammary glandular cells - Lactation"	"Plasma membrane, Cytosol"		"CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039"	"unprognostic (3.35e-2)"	"prognostic unfavorable (1.42e-5)"	"unprognostic (9.69e-3)"	"unprognostic (4.09e-2)"	"unprognostic (3.46e-3)"	"unprognostic (1.55e-2)"	"unprognostic (3.09e-2)"	"unprognostic (4.74e-3)"	"unprognostic (3.15e-1)"	"unprognostic (3.15e-1)"	"unprognostic (2.87e-3)"	"unprognostic (1.05e-1)"	"prognostic unfavorable (7.16e-5)"	"unprognostic (4.50e-2)"	"unprognostic (9.62e-2)"	"unprognostic (1.35e-2)"	"unprognostic (7.03e-3)"	372.8	30.9	25.0	14.9	44.2	18.7	271.6	67.3	49.9	31.7	0.0	25.5	11.5	18.0	6.2	63.6	15.2	6.6	21.9	39.9	15.0	11.8	191.4	54.1	7.2	84.4	75.7	16.3	18.6	8.5	72.4	12.1	101.7	69.0	3.0	4.3	38.3	14.3	27.9	89.4	28.8	5.3	12.5	8.8	63.6	11.9	33.7	9.6	21.2	2.3	3.0	27.0	31.8	60.8	179.1	182.0	81.7	56.7	130.1	87.2	176.9	34.3	43.3	35.5	64.6	190.6	116.7	58.8	29.2	26.3	99.5	144.0	79.2	157.8	6.5	30.0	358.0	123.9	140.0	257.2	36.8	67.5	19.2	84.2	40.4	90.8	21.0	12.1	40.1	54.8	193.2	50.7	12.6	304.1	78.9	105.5	161.1	28.1	107.1	64.1	47.8	116.5	40.3	220.7	205.0	117.0	50.6	1109.2	93.6	29.5	199.4	123.4	71.1	52.3	107.0	45.2	88.4	68.5	17.1	60.6	31.2	71.1	79.5	0.0	0.1	0.0	0.1	0.0	0.1	0.0	0.2	0.2	0.2	0.0	0.1	0.1	0.0	0.0	0.0	0.1	0.0	0.1	25.0	44.2	67.3	49.9	39.9	15.0	84.4	75.7	101.7	12.5	33.7	60.8	9.6	25.6	126.0	28.4	7.4	7.8	12.7	33.2	8.0	28.7	442.9	165.4	5.9	21.5	28.4	11.0	6.2	32.0	12.8	35.7	3.9	19.2	1.5	19.6	19.8	10.8	18.1	20.6	11.9	29.2	77.7	13.4	33.6	17.1	12.7	29.9	10.8	244.1	13.9	30.3	12.5	22.3	22.4	9.8	6.2	3.4	16.4	7.0	17.8	4.7	6.2	14.1	8.2	11.6	17.6	19.1	23.6	11.3	9.7	60.4	6.5	5.9	23.7	13.1	0.0	9.0	14.9	1.8	11.7	34.1	13.8	29.6	10.6	27.9	27.4	19.6
FDXR	"ADR, ADXR"	ENSG00000161513	"Ferredoxin reductase"	P22570	17	74862497-74873031	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport"	Oxidoreductase	"Deafness, Disease variant, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	8	"adrenal gland: 343.1"	"Group enriched"	"Detected in many"	7	"Granulosa cells: 329.3;Theca cells: 794.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"BEWO: 89.5;Hep G2: 173.5"					"Low region specificity"	"Detected in all"			"CAB008597, CAB009818, HPA044393, HPA053673"	Enhanced		Enhanced	Mitochondria		NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 52: Non-specific - Transcription"	Mitochondria		"CAB008597: AB_1615557, CAB009818: AB_2102601, HPA044393: AB_2678927, HPA053673: AB_2682225"	"unprognostic (2.69e-2)"	"unprognostic (1.17e-3)"	"unprognostic (7.51e-2)"	"prognostic favorable (2.38e-4)"	"unprognostic (3.43e-2)"	"unprognostic (1.20e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.68e-2)"	"unprognostic (2.29e-1)"	"unprognostic (1.50e-1)"	"unprognostic (1.09e-1)"	"unprognostic (6.30e-2)"	"unprognostic (1.42e-2)"	"unprognostic (1.19e-2)"	"unprognostic (4.50e-2)"	"unprognostic (4.03e-2)"	"unprognostic (2.13e-1)"	3.9	343.1	6.9	2.4	8.4	2.2	3.8	7.8	8.1	7.8	8.6	9.7	4.6	6.7	5.1	26.0	12.9	4.1	6.0	6.6	6.7	6.5	14.9	5.3	2.9	7.6	7.9	20.5	12.9	5.9	4.1	3.0	7.5	6.7	3.2	0.5	7.1	4.4	7.7	16.4	5.6	2.3	7.4	33.9	7.6	45.6	7.0	4.7	6.0	1.7	2.5	6.2	10.5	7.5	12.5	65.6	9.6	10.8	6.8	9.1	89.5	14.8	15.9	8.6	17.1	18.3	10.8	29.6	2.6	6.2	4.8	24.9	6.9	18.4	2.5	27.9	15.2	22.6	10.6	173.5	19.0	5.0	75.1	29.2	20.3	9.1	3.1	7.0	43.9	10.9	36.1	4.8	13.4	53.4	19.7	10.6	5.5	11.8	14.5	10.6	16.4	16.2	7.1	21.0	5.2	12.1	10.0	21.7	11.2	10.9	47.4	4.7	20.5	5.9	51.9	9.4	7.4	12.7	2.3	6.5	16.1	7.7	20.6	1.7	6.0	5.0	5.6	4.5	5.0	4.8	5.1	6.8	7.3	2.4	4.4	5.4	2.0	10.3	3.4	1.4	15.4	5.2	6.9	8.4	7.8	8.1	6.6	6.7	7.6	7.9	7.5	7.4	7.0	7.5	4.0	3.2	3.9	7.5	8.2	9.7	17.8	42.6	17.1	4.9	6.6	8.4	3.8	5.7	23.3	9.2	4.2	53.2	2.8	18.6	5.9	11.1	6.5	28.2	4.3	4.6	7.1	4.0	1.4	7.9	18.9	12.9	13.7	3.5	5.7	329.3	12.5	13.9	23.1	3.3	2.2	13.1	36.7	6.2	2.7	14.9	5.9	4.6	5.4	1.0	3.9	11.4	8.2	3.0	1.3	9.0	16.9	4.5	7.1	5.2	24.9	21.7	73.6	5.1	0.0	6.2	18.3	6.3	6.1	33.7	18.2	46.1	8.6	794.1	20.3	17.4
FMO1		ENSG00000010932	"Flavin containing dimethylaniline monoxygenase 1"	Q01740	1	171248471-171285978	"Enzymes, Metabolic proteins, Predicted membrane proteins"		"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	10	"kidney: 199.0"	"Group enriched"	"Detected in many"	7	"Proximal enterocytes: 97.9;Proximal tubular cells: 196.9"	"Cancer enriched"	"Detected in many"	8	"renal cancer: 18.0"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	7	"HSkMC: 20.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA078132	Approved					NA	NA			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 7: Kidney - Transmembrane transport"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA078132: "	"unprognostic (1.04e-1)"	"unprognostic (1.05e-2)"	"unprognostic (5.87e-2)"	"unprognostic (1.34e-1)"	"unprognostic (5.32e-3)"	"unprognostic (1.89e-2)"	"unprognostic (1.04e-1)"	"unprognostic (4.04e-1)"	"unprognostic (9.16e-2)"	"unprognostic (9.03e-2)"	"unprognostic (1.36e-2)"	"unprognostic (2.23e-1)"	"prognostic favorable (2.81e-4)"	"unprognostic (6.49e-4)"	"unprognostic (1.40e-1)"	"unprognostic (3.58e-1)"	"unprognostic (1.37e-1)"	5.1	5.6	0.1	0.5	0.1	0.0	10.0	0.1	0.3	6.3	0.3	0.4	0.1	3.1	0.1	3.5	4.2	5.2	0.7	0.1	0.1	199.0	2.9	1.5	0.4	0.1	0.1	5.0	2.4	1.1	1.8	2.3	0.1	0.4	0.2	0.0	5.4	0.7	0.1	10.4	20.2	4.2	0.1	0.0	0.9	1.6	0.1	7.4	2.3	0.8	10.8	2.5	1.7	0.1	0.0	0.0	0.0	0.0	2.7	1.0	0.0	0.0	1.2	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	20.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.3	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	5.0	0.0	0.0	0.3	3.0	3.2	0.5	0.0	12.5	0.0	0.5	1.1	10.0	2.8	0.0	3.7	0.0	0.3	0.0	0.0	13.7	0.0	0.7	0.0	0.1	1.1	0.0	0.0	0.1	0.0	0.1	18.7	0.0	0.0	0.0	3.2	0.0	0.3	0.4	0.0	0.1	2.9	0.0	0.0	0.0	1.5	10.8	0.9	1.8	0.0	0.0	0.0	0.0	0.0	0.2	0.0	3.8	2.6	0.0	0.1	97.9	196.9	0.0	0.0	6.6	0.5	4.7	0.0	0.1	1.4	2.3	0.8	1.0	2.6	1.4	0.1
FMO2		ENSG00000094963	"Flavin containing dimethylaniline monoxygenase 2"	Q99518	1	171185249-171212686	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 69.7;lung: 93.9"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 187.0;Alveolar cells type 1: 461.6;Club cells: 204.7;Fibroblasts: 98.7"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	57	"ASC diff: 30.6;ASC TERT1: 13.7;HSkMC: 37.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA028261	Approved					NA	NA				"Cluster 82: Adipose tissue - ECM organization"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"			"HPA028261: AB_10601012"	"unprognostic (1.85e-2)"	"unprognostic (3.14e-2)"	"unprognostic (7.44e-2)"	"unprognostic (3.75e-2)"	"unprognostic (2.80e-1)"	"unprognostic (1.37e-2)"	"unprognostic (1.66e-3)"	"unprognostic (3.00e-2)"	"unprognostic (2.74e-1)"	"unprognostic (1.58e-2)"	"unprognostic (1.16e-1)"	"unprognostic (4.28e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.26e-3)"	"unprognostic (3.47e-1)"	"unprognostic (1.62e-1)"	"unprognostic (3.83e-2)"	69.7	24.0	1.5	1.3	2.4	0.1	47.8	1.3	1.4	6.6	2.9	6.5	0.9	5.1	7.7	65.9	33.3	4.6	50.0	0.8	4.1	10.4	4.3	93.9	11.6	2.2	1.7	4.3	5.5	4.9	6.3	0.3	1.7	5.5	1.7	0.9	36.5	2.9	17.6	4.5	4.2	3.9	1.5	0.7	6.8	1.1	4.7	8.6	12.0	20.3	11.8	4.5	11.6	1.1	0.0	0.0	0.0	0.0	30.6	13.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	37.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	2.4	1.3	1.4	0.8	4.1	2.2	1.7	1.7	1.5	4.7	1.1	187.0	461.6	21.7	2.6	0.1	0.4	4.4	36.0	2.8	0.4	14.5	69.1	9.2	0.0	204.7	1.8	0.0	0.0	0.5	0.0	0.0	0.5	5.5	0.1	0.1	69.1	0.0	0.0	0.1	0.0	0.0	98.7	0.0	0.0	3.8	0.0	3.3	0.0	0.0	0.0	0.0	0.0	12.2	0.0	0.7	2.8	0.9	1.8	0.0	37.5	0.0	0.2	0.0	2.0	0.1	1.3	0.0	0.0	2.5	3.7	0.0	10.2	36.0	0.6	0.0	9.7	48.5	0.3	0.1	7.4	0.0	0.0	1.1	1.6	0.0	1.2
FMO3	FMOII	ENSG00000007933	"Flavin containing dimethylaniline monoxygenase 3"	P31513	1	171090901-171117819	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"		"Monooxygenase, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	41	"liver: 1123.3"	"Cell type enriched"	"Detected in some"	13	"Hepatocytes: 412.3"	"Cancer enriched"	"Detected in many"	13	"liver cancer: 94.9"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	4	"ASC diff: 34.6;ASC TERT1: 26.0"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA013750	Enhanced					NA	NA				"Cluster 62: Liver - Hemostasis"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 2: Hepatocytes - Metabolism"			"HPA013750: AB_1848968"	"unprognostic (1.87e-2)"	"unprognostic (6.30e-2)"	"unprognostic (1.00e-1)"	"unprognostic (6.81e-3)"	"unprognostic (2.64e-1)"	"unprognostic (1.31e-3)"	"prognostic favorable (3.46e-4)"	"prognostic favorable (5.60e-5)"	"unprognostic (2.95e-1)"	"unprognostic (9.34e-2)"	"unprognostic (3.02e-1)"	"unprognostic (7.21e-2)"	"prognostic unfavorable (1.13e-4)"	"unprognostic (1.84e-1)"	"unprognostic (2.59e-1)"	"unprognostic (3.45e-1)"	"unprognostic (7.27e-2)"	27.2	12.4	2.5	0.9	2.7	0.4	6.8	2.5	3.6	1.2	2.3	1.4	1.8	1.3	3.0	5.1	13.3	1.8	4.2	2.3	2.6	14.0	1123.3	18.7	4.9	5.0	2.7	0.3	4.5	4.2	4.3	0.2	3.1	1.1	0.7	0.1	5.1	0.4	4.6	4.3	2.2	1.6	4.0	0.4	3.9	0.5	2.8	1.4	2.6	3.1	9.1	1.0	0.9	2.6	0.0	0.0	0.0	0.0	34.6	26.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.3	0.4	0.0	7.2	0.0	0.0	0.0	0.6	0.0	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.3	0.1	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.5	2.7	2.5	3.6	2.3	2.6	5.0	2.7	3.1	4.0	2.8	2.6	2.7	12.8	0.5	0.0	0.7	0.4	0.4	2.7	0.0	0.0	0.1	0.3	0.4	7.2	17.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	2.2	0.0	4.7	0.0	29.5	0.0	0.0	0.0	12.2	0.0	0.0	0.0	0.0	6.8	412.3	0.0	0.0	0.0	0.0	4.1	9.5	0.8	0.0	0.3	0.1	1.8	1.0	0.0	0.5	0.0	7.1	0.1	0.1	0.0	0.0	0.0	0.1	0.0	0.2	22.7	0.2	6.6	1.3	6.3	0.4	0.1	0.4	0.4	0.0	0.8	0.2	0.0	0.1
FMO4	FMO2	ENSG00000076258	"Flavin containing dimethylaniline monoxygenase 4"	P31512	1	171314183-171342084	"Enzymes, Metabolic proteins, Predicted membrane proteins"		"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"kidney: 48.6;liver: 61.3"	"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 29.4;Hepatocytes: 22.1;Oligodendrocytes: 18.5;Proximal enterocytes: 16.5;Proximal tubular cells: 49.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"EFO-21: 5.7;HSkMC: 6.6"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"HPA049100, HPA072438"	Approved		Approved	Vesicles,Cytosol		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	"Vesicles, Cytosol"		"HPA049100: AB_2680629, HPA072438: "	"unprognostic (1.83e-2)"	"unprognostic (1.17e-1)"	"unprognostic (6.18e-2)"	"unprognostic (3.01e-2)"	"unprognostic (8.27e-2)"	"unprognostic (4.13e-1)"	"prognostic favorable (1.09e-4)"	"prognostic favorable (7.45e-4)"	"unprognostic (3.12e-2)"	"unprognostic (2.15e-1)"	"unprognostic (5.99e-2)"	"unprognostic (2.90e-1)"	"prognostic favorable (6.96e-4)"	"unprognostic (1.03e-1)"	"unprognostic (1.69e-1)"	"unprognostic (7.45e-3)"	"unprognostic (1.95e-1)"	3.7	2.6	2.2	1.9	3.1	0.9	4.1	2.8	3.0	3.3	3.1	5.0	5.4	2.7	6.3	2.3	3.5	4.9	5.2	2.1	2.6	48.6	61.3	3.2	2.9	3.1	2.8	3.8	2.4	4.7	1.9	2.3	3.3	3.1	4.8	0.7	2.0	2.2	1.0	3.4	9.2	2.0	2.6	3.1	5.0	1.7	3.1	3.6	3.2	2.1	3.3	2.4	2.9	3.5	0.1	0.1	0.3	0.4	4.1	3.4	0.2	0.8	3.7	1.1	1.2	0.6	5.3	3.7	5.7	0.1	2.0	0.2	0.7	1.0	1.6	1.6	0.8	0.0	0.0	0.0	0.6	0.7	0.8	6.6	2.4	0.4	1.0	0.4	0.2	1.7	0.2	2.3	0.5	0.7	1.6	1.3	0.4	0.9	1.2	0.4	0.4	2.1	2.6	0.0	0.1	0.0	1.2	1.0	2.4	4.1	2.2	1.0	0.1	0.9	0.3	1.0	0.7	2.9	1.0	2.2	1.8	1.1	0.8	0.2	1.0	0.3	0.9	1.6	0.7	1.2	0.8	1.3	0.9	1.8	1.2	0.9	0.1	1.7	1.1	1.2	2.1	0.8	2.2	3.1	2.8	3.0	2.1	2.6	3.1	2.8	3.3	2.6	3.1	3.5	2.2	0.0	2.6	7.2	3.2	2.8	4.6	5.0	2.8	0.0	2.3	2.0	3.7	2.8	3.7	9.2	0.0	2.8	0.6	7.1	29.4	2.3	5.7	3.8	1.7	1.4	1.2	0.0	0.1	1.4	1.2	6.6	8.2	1.7	1.3	1.5	2.9	22.1	3.7	0.0	0.1	3.2	2.0	5.9	1.3	1.3	1.5	2.7	5.4	2.8	1.6	1.8	1.0	0.0	18.5	1.1	0.7	0.4	1.1	0.9	16.5	49.5	7.3	0.0	0.0	1.8	2.1	0.3	0.5	1.9	1.6	1.9	1.7	2.0	2.8	1.8
FMO5		ENSG00000131781	"Flavin containing dimethylaniline monoxygenase 5"	P49326	1	147175351-147243050	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Monooxygenase, Oxidoreductase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	6	"liver: 683.3"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 64.2;Cholangiocytes: 133.0;Hepatocytes: 265.4;Proximal enterocytes: 108.8;Proximal tubular cells: 69.2"	"Cancer enriched"	"Detected in many"	7	"liver cancer: 43.0"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enriched"	"Detected in some"	4	"Hep G2: 41.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA012373	Enhanced		Supported	"Endoplasmic reticulum,Cytosol"		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 2: Hepatocytes - Metabolism"	"Endoplasmic reticulum, Cytosol"		"HPA012373: AB_1848975"	"unprognostic (2.70e-1)"	"unprognostic (1.28e-1)"	"unprognostic (1.33e-1)"	"unprognostic (2.06e-2)"	"unprognostic (1.39e-1)"	"unprognostic (3.96e-2)"	"unprognostic (2.43e-2)"	"unprognostic (2.94e-2)"	"unprognostic (1.10e-1)"	"unprognostic (1.85e-2)"	"unprognostic (2.93e-1)"	"unprognostic (1.13e-1)"	"prognostic favorable (1.34e-6)"	"unprognostic (3.77e-1)"	"unprognostic (1.38e-1)"	"unprognostic (1.85e-1)"	"unprognostic (4.11e-2)"	3.1	5.7	2.0	5.1	2.9	2.0	46.1	3.9	2.8	7.8	0.5	41.3	71.3	2.8	6.9	1.2	3.6	15.8	3.1	2.1	2.4	51.5	683.3	27.1	4.0	4.2	2.9	4.1	48.1	68.3	6.7	2.4	4.8	9.7	46.6	0.9	32.7	4.0	0.8	11.6	73.9	3.5	3.2	4.0	120.1	5.2	3.1	1.1	2.0	1.4	2.5	3.9	1.5	5.6	0.1	1.1	0.6	0.1	2.8	0.8	0.9	0.7	0.5	0.3	0.8	0.7	2.4	0.4	0.8	0.8	0.2	0.4	0.0	0.0	0.0	1.4	0.2	1.6	0.1	41.7	0.9	1.4	9.0	1.3	0.2	0.4	0.0	0.4	0.6	0.2	0.1	0.1	1.5	1.4	0.2	0.7	2.8	5.3	0.8	0.4	0.5	0.4	3.4	0.6	0.5	0.3	0.9	2.8	1.3	1.3	2.1	10.4	1.1	0.0	0.3	0.9	0.0	0.3	0.0	0.3	1.1	0.5	0.3	7.0	12.9	4.1	2.0	5.9	0.3	4.7	0.5	0.6	5.4	8.5	0.3	1.3	1.3	1.2	1.8	2.5	1.6	3.9	2.0	2.9	3.9	2.8	2.1	2.4	4.2	2.9	4.8	3.2	3.1	5.6	2.8	9.6	64.2	11.1	6.4	1.7	3.9	0.9	1.8	2.0	17.5	6.7	1.9	133.0	10.4	14.7	0.0	1.5	1.7	60.8	7.9	7.5	7.7	2.5	1.8	2.7	6.7	4.8	8.2	5.9	1.1	2.9	24.5	6.1	5.7	9.8	5.0	265.4	4.0	3.3	6.4	34.4	4.1	10.0	2.3	4.5	2.8	4.6	28.4	10.3	5.3	0.2	4.1	10.1	17.5	7.0	29.0	1.5	0.4	5.6	108.8	69.2	18.1	1.3	0.0	2.2	1.0	5.9	0.9	1.3	1.6	1.4	2.6	6.6	20.7	6.4
FTH1	"FHC, FTH, FTHL6, PIG15, PLIF"	ENSG00000167996	"Ferritin heavy chain 1"	P02794	11	61959718-61967634	"Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Iron storage"	Oxidoreductase	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Langerhans cells: 49889.9;monocytes: 34409.9;Proximal enterocytes: 28837.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"ASC diff: 23933.9;HHSteC: 24849.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB008623	Approved					NA	NA		5600000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 32: Brain & Lymphoid tissue - Unknown function"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 3: Monocytes - Immune response regulation"			"CAB008623: "	"unprognostic (7.15e-2)"	"unprognostic (1.52e-2)"	"unprognostic (2.27e-1)"	"unprognostic (2.00e-2)"	"unprognostic (2.53e-1)"	"prognostic unfavorable (7.56e-5)"	"prognostic unfavorable (6.18e-4)"	"unprognostic (3.08e-2)"	"unprognostic (2.48e-2)"	"unprognostic (6.65e-2)"	"unprognostic (2.44e-2)"	"unprognostic (8.13e-2)"	"prognostic unfavorable (5.20e-5)"	"unprognostic (2.99e-1)"	"unprognostic (4.89e-2)"	"unprognostic (3.44e-1)"	"unprognostic (5.83e-2)"	6767.7	5191.4	5741.8	3546.9	5464.0	4734.2	5696.1	5591.9	7973.3	3973.1	4801.2	4701.2	1819.9	3712.8	2421.8	4025.0	3195.6	1995.6	4779.5	5252.8	5737.2	6092.3	3500.8	6057.7	1460.4	6416.7	5812.4	3069.9	3883.8	1696.4	2105.4	1800.3	6188.9	2778.8	3357.4	3123.7	3533.1	1514.8	4695.5	2125.0	4331.6	2040.7	6506.2	3496.3	4044.1	769.5	6153.5	1109.8	3167.6	2766.8	1291.2	4718.0	3163.8	6630.2	3029.8	8290.2	1236.6	3293.8	23933.9	11490.1	6794.4	2684.1	11547.3	2694.6	2698.6	1011.0	4065.8	345.3	16669.6	7830.0	10259.7	5035.8	1118.8	2235.9	1733.9	1439.0	542.9	1720.3	10802.1	6692.1	24849.2	821.6	2626.6	15711.1	10758.7	5384.0	10038.1	8476.6	3427.6	1970.7	2622.1	3874.4	9546.5	4080.7	935.3	1361.8	2114.6	10461.4	13675.6	914.9	1508.5	2502.3	13877.6	8068.8	1044.8	1325.0	9113.3	1005.9	4645.6	4045.3	1790.3	1098.4	3791.5	8310.7	1978.7	3727.4	1732.0	662.7	2516.5	1088.1	11353.7	363.1	2030.4	29466.0	19068.5	15453.6	2306.3	22407.8	2274.9	4088.8	3267.1	2296.9	9762.5	4113.3	2710.5	2108.2	45110.1	1981.1	27515.2	7217.1	4321.5	22214.4	5741.8	5464.0	5591.9	7973.3	5252.8	5737.2	6416.7	5812.4	6188.9	6506.2	6153.5	6630.2	3864.7	1317.3	2890.3	319.3	3200.9	5157.7	7723.2	23426.3	3495.0	881.7	9884.9	10192.4	11.7	4466.7	11711.1	1918.2	573.4	4541.1	4513.5	13653.9	10888.0	10748.7	274.2	4921.8	2908.5	4303.3	2520.6	6318.6	252.8	11073.9	6803.9	5931.3	2059.7	8005.0	6736.0	1798.6	3266.1	5199.9	18411.3	738.6	153.7	3927.4	10379.8	13784.1	49889.9	527.7	4666.1	22792.0	7116.5	183.6	34409.9	12189.1	1699.3	153.3	1031.0	7813.2	7936.8	3818.1	1789.1	12995.8	28837.7	21355.6	5978.6	3311.6	2084.0	2686.9	6139.1	585.4	927.1	1983.6	3555.6	4622.6	5225.4	2496.8	4921.7	18650.3
FTMT	MtF	ENSG00000181867	"Ferritin mitochondrial"	Q8N4E7	5	121851882-121852833	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Iron storage"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	542	"testis: 54.1"	"Cell type enriched"	"Detected in some"	6	"Early spermatids: 761.5"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"									NA	NA				"Cluster 36: Testis - Spermatogenesis"		"Cluster 23: Spermatids - Flagellum & Golgi organization"																		"unprognostic (4.39e-2)"			0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	54.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.4	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	761.5	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	123.2	5.6	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.4	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	27.0	2.7	0.0	0.0	0.0	0.0	0.0	0.0	0.1
FTO	"ALKBH9, KIAA1752, MGC5149"	ENSG00000140718	"FTO alpha-ketoglutarate dependent dioxygenase"	Q9C0B1	16	53701692-54158512	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase, Transferase"	"Disease variant, Obesity"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Astrocytes: 173.3;Excitatory neurons: 226.1;Inhibitory neurons: 240.7;Oligodendrocyte precursor cells: 210.6;Oligodendrocytes: 282.5;Respiratory ciliated cells: 182.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017123, HPA041086, HPA068695"	Enhanced		Supported	Vesicles,Cytosol		No	No		540000	"Cluster 27: Non-specific - Gene expression"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	Cytosol	Vesicles	"CAB017123: , HPA041086: AB_2677293, HPA068695: AB_2732117"	"unprognostic (9.74e-2)"	"unprognostic (2.49e-1)"	"unprognostic (9.30e-2)"	"unprognostic (1.24e-2)"	"unprognostic (1.81e-1)"	"unprognostic (2.09e-2)"	"unprognostic (2.95e-2)"	"unprognostic (1.41e-1)"	"unprognostic (8.67e-2)"	"unprognostic (1.02e-1)"	"unprognostic (3.88e-2)"	"unprognostic (6.80e-2)"	"unprognostic (1.44e-1)"	"unprognostic (5.81e-3)"	"unprognostic (1.78e-1)"	"unprognostic (4.30e-3)"	"unprognostic (6.11e-3)"	24.4	33.6	31.8	12.5	36.6	8.2	36.3	30.1	37.7	25.8	31.0	22.2	7.7	26.9	21.4	17.2	25.3	21.6	27.1	35.2	39.5	25.0	17.4	36.8	15.0	29.2	31.3	27.2	20.7	40.6	26.2	20.1	31.9	20.0	14.1	38.4	18.9	23.9	33.1	21.4	12.5	29.9	30.5	16.4	15.0	8.3	33.8	17.0	27.5	23.0	14.8	21.9	18.5	43.9	15.1	26.8	35.0	35.9	67.3	50.4	11.5	35.6	32.2	29.3	8.5	16.8	19.3	34.4	38.2	46.3	16.6	21.7	32.4	34.9	42.5	16.0	25.5	15.5	33.6	31.7	46.2	12.5	17.1	55.9	36.5	26.6	32.5	36.6	44.1	25.1	15.2	8.4	48.1	11.8	28.0	19.2	18.1	15.5	17.5	42.2	52.9	32.3	44.6	12.3	43.0	29.7	40.4	23.6	10.8	33.7	31.1	29.3	42.4	36.4	23.9	19.8	22.1	15.9	13.9	35.0	33.9	22.9	28.7	14.9	17.9	9.7	25.6	22.7	32.4	17.6	24.4	25.9	23.8	17.4	22.5	24.4	2.9	26.4	16.5	9.5	26.6	23.1	31.8	36.6	30.1	37.7	35.2	39.5	29.2	31.3	31.9	30.5	33.8	43.9	15.1	80.1	62.0	173.3	10.3	12.4	10.0	8.6	13.6	22.8	69.1	39.5	22.3	15.7	54.4	7.3	12.5	9.3	10.2	4.8	7.9	9.0	39.1	11.0	18.3	17.4	6.6	9.7	226.1	5.7	7.4	23.1	9.7	9.9	25.9	16.8	11.0	13.8	9.2	16.8	240.7	6.6	10.2	9.0	13.2	69.9	14.3	11.8	10.6	134.0	5.5	19.6	10.3	210.6	282.5	5.5	5.0	15.1	18.7	6.0	4.5	15.8	182.7	14.1	13.1	21.6	16.8	3.5	3.4	11.0	9.1	5.1	12.9	17.8	6.3	7.9
FXN	"CyaY, FA, FARR, FRDA, X25"	ENSG00000165060	Frataxin	Q16595	9	69035751-69079076	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters"	"Heme biosynthesis, Ion transport, Iron storage, Iron transport, Transport"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Hepatocytes: 69.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB022164, HPA068304"	Supported		Supported	Mitochondria,Cytosol		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 55: Plasma cells - Humoral immune response"	Mitochondria	Cytosol	"CAB022164: , HPA068304: AB_2685970"	"unprognostic (3.38e-2)"	"unprognostic (1.54e-1)"	"unprognostic (7.47e-2)"	"unprognostic (2.37e-3)"	"unprognostic (4.08e-2)"	"unprognostic (1.24e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.99e-1)"	"unprognostic (4.19e-2)"	"unprognostic (2.53e-1)"	"unprognostic (2.71e-3)"	"unprognostic (1.10e-1)"	"unprognostic (9.06e-2)"	"unprognostic (1.67e-1)"	"unprognostic (4.74e-2)"	10.3	20.1	8.9	7.8	9.2	29.1	10.1	9.7	8.9	9.3	11.7	10.4	7.4	12.1	12.1	9.5	10.2	5.3	27.0	9.0	10.4	12.9	46.3	7.1	9.8	9.8	10.2	17.6	15.1	22.2	8.1	9.1	9.8	10.2	12.3	4.1	11.7	13.6	25.5	5.2	7.7	13.3	9.5	12.6	10.1	10.7	9.9	5.4	10.4	19.8	10.4	12.3	7.9	10.4	27.0	22.1	34.2	17.0	15.7	23.1	34.3	18.6	16.3	28.0	21.2	11.8	16.6	45.9	14.0	19.5	28.8	28.6	41.8	42.6	34.9	53.9	47.5	66.2	14.1	87.2	26.7	48.7	27.7	25.7	33.7	27.8	29.9	9.6	37.7	28.0	50.3	43.9	26.1	25.6	14.0	21.0	47.5	53.1	42.8	32.7	24.0	32.0	32.2	21.5	26.9	12.1	19.2	12.5	20.7	24.3	14.1	14.4	22.7	18.0	32.0	24.1	27.6	11.6	11.4	27.8	8.5	39.7	18.5	8.1	39.9	0.4	48.6	45.4	37.5	36.3	48.0	48.4	42.8	22.7	61.6	59.8	1.9	60.8	36.2	33.2	43.3	49.5	8.9	9.2	9.7	8.9	9.0	10.4	9.8	10.2	9.8	9.5	9.9	10.4	11.0	3.2	11.5	13.1	19.9	9.7	19.8	36.6	14.8	6.8	16.9	20.8	38.2	10.0	10.5	14.7	4.2	39.9	14.9	4.9	21.5	17.5	2.4	11.7	22.5	16.9	7.2	56.1	14.2	14.7	22.3	14.7	14.3	8.7	7.0	15.4	11.0	69.0	33.4	0.0	18.6	15.3	18.3	22.1	16.1	6.3	15.8	13.9	17.8	9.4	18.3	7.6	28.8	6.6	10.8	15.0	3.7	13.2	42.0	17.1	5.8	27.2	7.4	1.6	13.1	10.1	19.8	5.1	32.3	29.8	8.1	14.6	17.1	27.9	17.5	14.1
G6PD	G6PD1	ENSG00000160211	"Glucose-6-phosphate dehydrogenase"	P11413	X	154531391-154547572	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Carbohydrate metabolism, Glucose metabolism"	Oxidoreductase	"Cancer-related genes, Disease variant, Hereditary hemolytic anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 105.9"	"Cell type enhanced"	"Detected in many"		"monocytes: 112.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"eosinophil: 412.7"	"Lineage enriched"	"Detected in all"	5	"granulocytes: 412.7"	"Cell line enhanced"	"Detected in all"		"A549: 2333.8;MCF7: 883.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000247, HPA000834"	Enhanced		Enhanced	"Centriolar satellite,Cytosol"		No	No		2400000	"Cluster 49: Eosinophils - Unknown function"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 3: Monocytes - Immune response regulation"	Cytosol	"Centriolar satellite"	"HPA000247: AB_1078978, HPA000834: AB_1078977"	"unprognostic (1.73e-2)"	"unprognostic (1.53e-3)"	"unprognostic (1.13e-2)"	"unprognostic (1.02e-1)"	"unprognostic (7.78e-2)"	"unprognostic (4.34e-2)"	"prognostic unfavorable (9.45e-13)"	"unprognostic (2.78e-2)"	"unprognostic (1.66e-1)"	"unprognostic (1.76e-2)"	"unprognostic (1.09e-1)"	"unprognostic (3.66e-1)"	"unprognostic (2.89e-3)"	"unprognostic (2.83e-1)"	"unprognostic (1.94e-1)"	"unprognostic (1.47e-1)"	"unprognostic (7.25e-2)"	40.7	39.1	19.9	30.2	21.8	105.9	31.9	20.5	28.3	20.6	20.0	13.9	13.1	21.6	13.3	54.3	19.3	46.5	14.3	21.3	22.7	12.7	6.5	29.4	28.9	25.4	22.2	24.1	13.0	9.6	27.5	13.7	24.5	12.2	13.1	26.1	21.2	14.4	4.2	21.3	12.4	25.6	19.7	26.9	18.1	54.0	26.1	26.2	45.9	5.1	37.2	33.8	22.4	21.9	168.5	2333.8	49.7	189.7	207.2	281.7	43.5	116.0	341.7	120.0	205.8	111.2	61.9	110.9	174.1	274.3	475.9	146.3	79.3	202.5	60.3	111.4	55.0	116.8	517.2	244.6	401.6	117.8	373.5	136.6	58.5	233.9	49.8	185.6	252.5	79.8	69.6	46.3	218.4	883.9	77.5	93.0	35.3	549.5	172.2	74.9	28.4	120.5	357.1	210.9	49.6	62.0	115.9	444.5	99.9	65.0	67.1	99.4	289.8	73.1	250.0	102.5	181.8	58.2	80.0	189.8	200.6	77.5	150.9	166.1	84.9	412.7	50.3	72.1	32.1	16.0	13.7	36.7	40.1	17.0	16.5	28.2	137.4	69.3	63.5	18.9	18.7	72.8	19.9	21.8	20.5	28.3	21.3	22.7	25.4	22.2	24.5	19.7	26.1	21.9	7.9	0.0	17.0	4.6	21.5	12.5	24.3	46.6	8.6	6.2	14.6	8.6	1.1	14.3	22.9	11.0	18.8	29.6	58.9	25.5	29.4	39.3	10.3	7.7	13.7	13.2	9.5	37.7	2.9	29.3	41.2	19.6	23.4	10.7	37.5	26.1	18.2	1.6	45.6	33.7	2.3	11.5	24.4	58.2	26.0	20.8	26.1	56.6	19.6	5.6	112.3	13.6	83.4	3.5	3.7	31.0	11.4	16.1	21.6	23.9	18.5	18.3	10.9	32.5	6.6	7.5	23.6	10.9	32.8	34.4	13.8	36.3	33.8	11.6	13.5	30.5
GAPDH	GAPD	ENSG00000111640	"Glyceraldehyde-3-phosphate dehydrogenase"	P04406	12	6534512-6538374	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Glycolysis, Immunity, Innate immunity, Translation regulation"	"Oxidoreductase, Transferase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in all"	4	"skeletal muscle: 27580.7;tongue: 18892.5"	"Cell type enhanced"	"Detected in all"		"Extravillous trophoblasts: 10357.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Not detected"	"Not detected"							"CAB005197, CAB016392, HPA040067, HPA061280, CAB079968"	Supported		Enhanced	"Nuclear membrane,Vesicles,Plasma membrane,Cytosol"		No	No		1400000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 16: Pancreatic endocrine cells - Mixed function"	"Plasma membrane, Cytosol"	"Nuclear membrane, Vesicles"	"CAB005197: AB_641107, CAB016392: AB_627678, CAB079968: , HPA040067: AB_10965903, HPA061280: AB_2684463"	"unprognostic (3.03e-1)"	"unprognostic (2.62e-3)"	"unprognostic (3.58e-2)"	"unprognostic (4.20e-1)"	"unprognostic (9.73e-3)"	"unprognostic (1.77e-3)"	"prognostic unfavorable (1.79e-6)"	"unprognostic (2.89e-3)"	"unprognostic (2.86e-1)"	"unprognostic (2.06e-2)"	"unprognostic (9.50e-3)"	"unprognostic (4.52e-1)"	"prognostic unfavorable (6.25e-10)"	"unprognostic (2.33e-1)"	"unprognostic (4.28e-1)"	"unprognostic (1.40e-1)"	"unprognostic (1.26e-2)"	1219.9	1815.8	2605.9	1191.3	2589.5	4608.5	1042.3	2869.0	3067.8	1163.8	2419.2	1720.0	1480.8	1080.9	769.9	2973.8	1042.8	1161.3	5572.8	2630.1	2880.0	2323.2	2557.9	1137.9	1388.3	2845.2	2861.3	1087.0	652.0	1616.0	1338.7	1190.6	2828.4	1241.0	1586.6	2386.8	1835.8	1238.7	27580.7	1775.5	1457.5	1424.4	2670.8	1208.5	1215.5	693.0	2985.1	1570.9	1022.1	18892.5	1861.0	1889.0	1672.9	2741.6	6063.0	10247.9	3109.5	4709.2	3026.2	5018.7	6516.0	4716.2	7218.1	7172.8	7491.2	7211.3	4091.6	7540.8	878.2	5947.4	4904.2	3359.8	3372.7	10829.1	5432.4	6263.1	3229.5	4224.9	5857.5	6279.2	3890.9	6710.2	3046.1	4089.0	3521.7	6553.0	7609.7	15565.8	7762.7	5052.4	2215.9	1484.1	8670.0	11849.8	7303.1	3247.3	10995.7	7254.7	3950.7	5849.8	5505.7	3512.8	7909.6	7115.9	2088.3	3331.0	4243.1	10206.4	5984.0	8874.7	1657.2	4311.2	4794.3	5049.0	5907.2	2717.1	7931.5	3178.4	2544.6	9374.4	10632.2	4050.5	8040.5	2575.4	4295.8	737.9	1325.8	2011.2	1171.4	1046.9	1364.8	1333.1	3253.6	652.5	757.6	886.9	1981.4	1227.8	1900.6	474.6	2126.1	6812.0	2605.9	2589.5	2869.0	3067.8	2630.1	2880.0	2845.2	2861.3	2828.4	2670.8	2985.1	2741.6	1036.7	237.2	259.5	228.2	1086.9	1818.8	2223.4	7367.5	4070.9	1157.6	1794.6	3689.2	40.4	1263.9	2213.7	1022.5	417.0	4237.7	1032.7	2579.6	3463.0	5198.9	759.8	770.1	702.4	1597.4	1324.3	1180.6	112.1	3794.5	10357.8	1127.1	1068.8	1021.8	562.3	2063.7	1242.9	1742.3	3895.3	2348.7	145.8	2351.2	2543.1	2586.7	2494.4	2257.7	889.4	2134.0	4220.8	86.2	3422.3	6177.9	1045.4	98.5	196.2	5681.8	3001.4	1026.9	2668.2	1714.0	5714.0	7286.7	864.3	1435.2	1150.4	1744.7	2827.8	429.9	476.2	3605.2	1600.7	4694.0	1514.9	1839.0	3140.9	2882.4
GAPDHS	"GAPD2, GAPDH-2, GAPDS"	ENSG00000105679	"Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic"	O14556	19	35533455-35545319	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	Glycolysis	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	19	"testis: 269.8"	"Cell type enriched"	"Detected in some"	4	"Late spermatids: 8717.5"	"Cancer enriched"	"Detected in single"	97	"melanoma: 13.3"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"A549: 22.4"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA042666	Enhanced		Approved	Nucleoplasm,Centrosome		NA	NA		7500000	"Cluster 52: Eosinophils - Transcription"	"Cluster 83: Testis - Spermatogenesis"	"Cluster 20: HeLa - Mitochondria"	"Cluster 31: Spermatids - Spermatogenesis"	Nucleoplasm	Centrosome	"HPA042666: AB_2678104"	"unprognostic (3.74e-1)"	"unprognostic (1.59e-1)"			"unprognostic (7.41e-2)"			"unprognostic (1.56e-1)"	"unprognostic (2.06e-1)"	"unprognostic (1.04e-1)"	"unprognostic (8.81e-2)"			"unprognostic (2.96e-1)"	"unprognostic (1.03e-1)"	"unprognostic (6.45e-3)"	"unprognostic (2.37e-1)"	1.2	2.7	0.4	4.1	1.3	2.4	0.2	1.2	1.3	0.0	0.1	0.6	3.3	2.7	0.0	3.0	1.9	3.6	4.0	0.2	0.5	0.9	0.3	1.9	6.5	0.3	0.4	3.4	5.2	0.0	0.1	1.1	0.4	2.0	0.0	3.5	5.1	0.0	1.6	13.9	3.2	0.0	0.1	5.2	2.4	269.8	0.8	0.0	11.4	0.0	0.0	1.5	0.1	1.5	6.5	22.4	6.4	9.6	0.0	0.0	5.4	1.9	0.0	0.0	0.0	13.8	10.4	10.7	2.9	0.0	2.6	7.6	0.0	0.0	0.0	10.5	11.2	7.1	16.7	7.1	0.1	6.4	8.3	0.0	0.0	0.0	0.0	3.9	0.0	10.3	17.6	6.0	0.0	19.6	2.5	3.0	8.6	4.1	3.1	7.6	4.3	8.3	0.0	6.1	11.3	5.1	2.4	5.7	7.0	4.3	4.8	2.7	2.1	7.2	7.9	1.8	2.7	16.9	4.8	6.2	3.9	11.4	2.6	0.0	0.1	0.2	0.1	0.1	0.3	0.1	0.0	0.3	0.2	0.3	0.2	0.2	0.0	0.2	0.0	0.1	0.0	0.1	0.4	1.3	1.2	1.3	0.2	0.5	0.3	0.4	0.4	0.1	0.8	1.5	0.0	0.0	0.0	0.0	0.0	2.4	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	1915.7	0.0	0.0	1.6	0.0	0.0	0.4	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.7	0.0	0.1	0.0	0.4	0.0	0.0	0.3	0.4	8717.5	24.8	2.4	44.4	0.0	0.2	0.0	0.0	1.0	0.5	0.0	0.0	28.6	0.0	0.0	0.0	0.1	0.0	0.0	26.3	0.0	0.1	33.4	18.2	0.0	0.1	0.0	0.1	0.1	0.0	0.0
GCDH	ACAD5	ENSG00000105607	"Glutaryl-CoA dehydrogenase"	Q92947	19	12891160-12914207	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, Glutaricaciduria"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 89.1"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 115.5;Proximal tubular cells: 147.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA043252, HPA048492"	Enhanced		Supported	Mitochondria		NA	NA			"Cluster 48: NK-cells - Unknown function"	"Cluster 15: Liver - Metabolism"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Mitochondria		"HPA043252: AB_2678390, HPA048492: AB_2680418"	"unprognostic (2.46e-1)"	"unprognostic (1.64e-3)"	"unprognostic (6.79e-3)"	"unprognostic (8.07e-3)"	"unprognostic (8.20e-3)"	"unprognostic (3.14e-2)"	"prognostic favorable (7.28e-5)"	"prognostic favorable (3.35e-4)"	"unprognostic (1.62e-1)"	"unprognostic (3.03e-2)"	"unprognostic (7.50e-3)"	"unprognostic (7.46e-2)"	"prognostic favorable (6.79e-8)"	"unprognostic (7.09e-3)"	"unprognostic (3.42e-1)"	"unprognostic (5.32e-2)"	"unprognostic (1.59e-1)"	16.8	17.8	20.2	11.2	22.4	13.0	15.6	22.1	23.3	10.2	21.8	13.2	11.8	12.6	8.6	14.0	15.2	8.4	29.3	19.2	19.4	24.5	89.1	9.3	16.8	20.7	20.9	16.8	15.5	11.5	10.6	5.4	21.0	13.6	8.5	5.5	20.0	11.5	30.5	10.1	13.0	8.2	19.9	12.8	18.6	4.5	20.9	17.8	11.9	27.1	11.9	14.9	9.9	22.7	22.9	14.1	15.0	27.5	21.4	9.8	13.8	17.2	11.1	21.6	15.7	26.9	10.8	33.0	31.9	10.5	10.8	15.6	20.8	16.4	10.6	28.6	22.8	21.0	24.6	33.1	24.8	43.7	18.8	13.8	19.9	15.3	16.1	8.8	18.1	44.4	51.8	11.4	10.7	28.9	51.7	41.7	16.7	22.0	36.1	48.2	15.3	68.9	12.6	12.1	32.3	18.9	22.8	22.6	16.7	9.6	17.8	29.3	13.3	18.0	12.9	29.9	18.2	59.5	32.2	34.6	11.0	50.7	15.4	13.9	13.9	8.5	18.8	12.1	18.8	18.1	23.2	21.0	24.0	19.5	30.9	23.8	3.1	38.8	9.8	14.7	21.4	20.0	20.2	22.4	22.1	23.3	19.2	19.4	20.7	20.9	21.0	19.9	20.9	22.7	6.0	3.2	5.3	25.5	21.2	7.9	14.5	13.3	11.4	14.2	17.3	10.8	10.0	22.8	8.6	11.0	25.0	16.2	17.2	11.6	52.8	14.0	2.6	7.7	10.0	7.3	15.6	60.4	7.1	11.2	21.5	10.2	12.8	10.9	7.0	19.5	13.6	115.5	21.5	8.4	7.4	13.8	16.2	14.4	5.0	1.8	13.1	9.9	17.8	5.6	20.7	18.6	18.6	14.6	15.1	10.2	9.7	12.8	25.4	11.3	17.4	147.8	7.2	12.3	0.0	13.7	9.8	8.3	7.4	13.4	5.3	16.3	20.9	33.0	20.6	12.1
GFER	"ALR, ERV1, HERV1, HPO1, HPO2, HSS"	ENSG00000127554	"Growth factor, augmenter of liver regeneration"	P55789	16	1984193-1987749	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins"		"Growth factor, Oxidoreductase"	"Cataract, Deafness, Disease variant, Primary mitochondrial disease"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 183.7;Early spermatids: 168.7;Proximal enterocytes: 371.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041227, HPA063553"	Approved		Enhanced	Mitochondria,Cytosol	"Secreted to blood"	NA	NA			"Cluster 26: Non-specific - Mitochondria"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 45: Enterocytes - Digestion"	"Mitochondria, Cytosol"		"HPA041227: AB_10795538, HPA063553: AB_2685038"	"unprognostic (5.35e-2)"	"unprognostic (2.11e-2)"	"unprognostic (3.08e-1)"	"unprognostic (4.42e-2)"	"unprognostic (3.15e-1)"	"unprognostic (2.63e-1)"	"unprognostic (1.27e-2)"	"unprognostic (1.42e-1)"	"unprognostic (1.11e-2)"	"unprognostic (2.30e-1)"	"unprognostic (1.56e-1)"	"unprognostic (5.93e-2)"	"prognostic favorable (4.06e-4)"	"unprognostic (4.93e-2)"	"unprognostic (3.64e-1)"	"unprognostic (3.56e-1)"	"unprognostic (1.09e-2)"	17.7	21.2	19.6	13.8	19.0	18.2	17.8	21.6	23.1	14.2	17.9	32.8	42.7	16.6	6.6	17.5	16.0	13.5	29.8	19.0	19.7	21.9	45.9	15.3	20.9	21.5	21.1	11.3	53.7	29.6	18.1	12.2	20.9	19.6	25.4	7.7	28.8	13.1	40.9	14.5	45.2	10.9	18.8	21.9	24.7	38.5	20.6	10.5	15.9	30.4	16.9	19.4	12.8	20.6	27.2	44.1	35.6	29.2	14.7	28.9	43.5	28.6	31.2	44.2	35.6	63.7	46.1	15.2	39.7	24.2	25.7	39.8	27.3	42.4	27.9	44.7	46.6	20.9	44.3	73.4	26.6	32.1	37.9	18.9	32.5	38.8	34.6	27.8	21.1	32.7	33.0	51.3	32.6	66.1	34.9	33.9	54.9	23.9	39.7	74.5	26.8	50.7	45.5	21.9	30.5	28.9	39.3	91.2	34.5	18.2	43.4	33.6	19.1	42.8	45.0	24.0	54.3	79.1	48.3	45.7	14.2	21.5	36.7	3.8	16.2	13.4	11.2	13.9	11.4	23.5	14.9	18.5	11.6	17.8	13.6	9.5	1.4	10.7	17.4	5.1	24.9	10.6	19.6	19.0	21.6	23.1	19.0	19.7	21.5	21.1	20.9	18.8	20.6	20.6	18.0	3.2	6.7	2.3	32.5	15.9	19.9	21.1	17.6	10.8	32.7	27.6	17.4	27.1	16.6	9.2	0.0	43.4	23.0	183.7	35.2	44.0	168.7	24.0	11.4	17.9	27.2	17.0	3.4	80.8	57.8	17.7	16.8	18.7	12.7	22.8	20.7	59.1	45.9	8.4	3.2	60.3	26.4	39.3	24.8	123.7	17.4	24.7	23.2	1.0	39.6	12.6	39.1	1.5	3.3	57.3	100.3	12.4	39.6	21.7	371.7	84.6	33.3	11.5	13.1	15.8	18.5	41.9	26.7	17.3	14.8	37.5	27.4	26.7	68.7	26.0
GFUS	"FX, P35B, SDR4E1, TSTA3"	ENSG00000104522	"GDP-L-fucose synthase"	Q13630	8	143612618-143618048	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Isomerase, Multifunctional enzyme, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"Adipocytes: 32.1;Cytotrophoblasts: 82.1;Extravillous trophoblasts: 156.4;Hofbauer cells: 69.9;Syncytiotrophoblasts: 87.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA023361	Approved		Approved	Nucleoplasm,Cytosol		Yes	No		850000	"Cluster 44: Non-specific - Transcription"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 21: OE19 - Mitochondria"	"Cluster 24: Non-specific - Transcription regulation"	Cytosol	Nucleoplasm	"HPA023361: AB_1858420"	"unprognostic (1.37e-2)"	"unprognostic (5.35e-2)"	"unprognostic (8.62e-3)"	"unprognostic (3.55e-2)"	"unprognostic (2.90e-1)"	"unprognostic (5.82e-2)"	"unprognostic (2.48e-2)"	"unprognostic (1.98e-1)"	"unprognostic (8.62e-2)"	"prognostic favorable (2.41e-4)"	"unprognostic (6.62e-3)"	"unprognostic (6.89e-2)"	"prognostic unfavorable (1.59e-4)"	"unprognostic (4.23e-2)"	"unprognostic (2.78e-2)"	"unprognostic (1.87e-2)"	"unprognostic (3.27e-2)"	36.3	37.2	21.6	27.7	21.1	52.3	34.0	21.4	25.9	28.6	21.7	45.9	69.2	24.8	19.2	88.7	24.0	29.3	32.1	20.7	21.3	37.5	86.6	28.4	29.1	23.5	21.9	19.0	99.5	22.8	44.0	24.4	22.8	45.0	37.6	6.5	70.9	24.2	30.2	81.5	52.4	19.4	20.2	35.7	111.4	49.4	21.0	26.6	32.1	18.4	27.1	31.0	36.0	22.5	85.6	67.1	29.2	99.7	28.6	26.1	54.1	70.3	73.0	50.2	38.1	78.5	94.3	37.5	64.6	52.5	21.2	60.6	47.8	100.8	23.2	101.7	53.8	58.7	103.0	93.4	57.2	42.2	67.1	30.3	47.4	31.7	127.3	42.2	84.3	61.9	66.4	57.0	41.2	267.5	39.8	53.2	45.8	267.7	87.1	47.1	26.3	122.3	106.1	94.8	67.3	45.9	53.3	100.2	73.0	23.0	133.5	58.8	75.5	34.8	132.0	35.1	67.6	34.1	30.2	29.0	52.8	91.6	54.7	34.9	27.4	42.9	40.3	38.5	43.0	35.2	43.1	46.8	30.1	40.1	31.5	38.5	31.0	63.6	33.8	54.5	57.5	45.7	21.6	21.1	21.4	25.9	20.7	21.3	23.5	21.9	22.8	20.2	21.0	22.5	32.1	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	12.9	0.0	0.0	0.0	0.0	82.1	11.2	0.0	0.0	0.0	0.0	0.0	0.0	5.4	0.0	0.0	0.0	0.0	156.4	7.2	0.0	0.0	0.0	0.0	0.0	0.0	69.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	5.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.3	0.0	0.0	0.0	0.0	87.7	1.7	0.0	0.0	0.0
GLDC	"GCSP, NKH"	ENSG00000178445	"Glycine decarboxylase"	P23378	9	6532467-6645729	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"liver: 173.5"	"Cell type enhanced"	"Detected in many"		"Collecting duct cells: 31.3;Cytotrophoblasts: 79.0;Extravillous trophoblasts: 41.6;Hepatocytes: 120.5;Oligodendrocyte precursor cells: 52.3;Proximal tubular cells: 31.6;Syncytiotrophoblasts: 46.0"	"Cancer enhanced"	"Detected in many"		"testis cancer: 41.4"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BEWO: 235.7;CACO-2: 58.2;HMC-1: 45.6;RPTEC TERT1: 95.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002318, HPA052887"	Enhanced		Supported	Nucleoplasm,Mitochondria		NA	NA		740000	"Cluster 37: B-cells - Transcription"	"Cluster 15: Liver - Metabolism"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 47: Cytotrophoblasts - Unknown function"	Mitochondria	Nucleoplasm	"HPA002318: AB_1849700, HPA052887: AB_2681980"	"unprognostic (6.73e-2)"	"unprognostic (1.19e-1)"	"unprognostic (6.50e-2)"	"prognostic unfavorable (5.24e-5)"	"unprognostic (1.50e-1)"	"unprognostic (7.87e-2)"	"unprognostic (1.81e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.40e-1)"	"unprognostic (1.74e-1)"	"unprognostic (2.47e-2)"	"unprognostic (2.69e-1)"	"prognostic favorable (3.50e-4)"	"unprognostic (1.65e-2)"	"unprognostic (1.27e-1)"	"unprognostic (5.62e-3)"	"unprognostic (1.17e-2)"	0.3	0.3	15.3	1.4	15.5	0.5	0.8	14.7	23.7	0.4	12.9	1.0	0.8	0.4	5.2	3.2	0.7	0.8	0.1	14.8	14.4	38.2	173.5	1.0	1.6	14.0	13.6	0.3	0.1	0.0	4.9	15.2	13.4	0.5	0.4	1.6	1.1	1.0	1.3	4.5	0.8	0.0	13.1	1.2	1.0	3.5	15.8	0.0	5.1	0.1	1.2	1.1	0.1	15.3	0.6	4.9	2.1	25.6	0.2	0.4	235.7	0.1	0.0	0.0	0.1	58.2	0.5	0.3	5.6	0.1	0.7	0.4	0.0	0.7	0.2	1.2	13.4	0.2	0.3	38.3	0.0	0.1	45.6	0.0	0.1	1.8	0.3	1.0	9.0	4.3	0.0	0.5	1.2	1.5	0.9	0.2	27.5	4.6	3.8	1.3	0.0	0.5	95.4	1.0	22.6	11.7	0.0	21.4	0.3	13.9	5.3	0.1	3.0	0.6	0.6	2.6	1.3	1.1	34.4	0.1	0.8	2.4	5.1	0.4	0.1	0.1	0.1	0.0	0.1	0.8	0.1	0.0	0.0	0.1	0.0	0.1	0.4	0.1	0.1	0.1	0.0	0.3	15.3	15.5	14.7	23.7	14.8	14.4	14.0	13.6	13.4	13.1	15.8	15.3	0.2	0.0	0.0	17.6	1.9	0.0	0.0	0.2	1.2	0.4	1.5	0.6	0.7	11.5	0.1	31.3	0.0	79.0	0.2	0.0	5.9	0.0	12.6	5.4	0.5	0.6	0.0	0.0	21.6	0.2	41.6	0.3	0.0	10.7	0.0	1.1	2.2	120.5	7.0	0.0	15.9	0.0	0.0	2.8	0.3	10.8	0.3	0.4	0.0	1.9	0.0	9.6	0.0	52.3	1.8	0.1	0.0	0.0	15.1	0.0	0.0	31.6	0.0	0.4	0.0	1.7	0.8	4.5	5.1	0.4	0.0	46.0	0.8	0.0	0.0	0.1
GLUD1	"GDH, GLUD"	ENSG00000148672	"Glutamate dehydrogenase 1"	P00367	10	87050202-87094843	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 816.4"	"Cell type enhanced"	"Detected in all"		"Astrocytes: 294.1;Hepatocytes: 402.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"Hep G2: 555.0"	"Low region specificity"	"Detected in all"							"HPA042492, HPA044839, HPA061369"	Approved		Supported	Mitochondria	"Intracellular and membrane"	NA	NA		23000000	"Cluster 26: Non-specific - Mitochondria"	"Cluster 15: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 41: Macrophages - Immune response"	Mitochondria		"HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494"	"unprognostic (1.48e-1)"	"unprognostic (1.26e-2)"	"unprognostic (3.55e-1)"	"unprognostic (1.07e-1)"	"prognostic favorable (3.81e-4)"	"unprognostic (1.31e-1)"	"unprognostic (1.91e-2)"	"unprognostic (5.50e-2)"	"unprognostic (2.06e-1)"	"unprognostic (4.57e-3)"	"prognostic unfavorable (1.76e-5)"	"unprognostic (1.13e-1)"	"prognostic favorable (1.44e-6)"	"unprognostic (2.29e-1)"	"unprognostic (4.23e-2)"	"unprognostic (7.19e-2)"	"unprognostic (4.27e-2)"	70.1	93.0	217.2	44.8	219.0	29.2	96.4	180.4	216.8	50.2	135.8	63.4	80.9	48.1	30.0	77.0	47.4	53.3	75.6	193.3	223.2	249.2	816.4	57.7	42.9	220.9	222.9	71.6	66.2	39.0	37.1	58.8	202.3	110.5	61.5	90.2	55.6	53.2	51.1	84.2	88.6	53.3	223.2	46.4	57.0	22.3	254.6	44.8	68.1	64.4	59.2	68.1	55.6	202.3	127.1	100.3	77.1	131.5	143.0	174.5	84.0	97.7	167.8	92.4	100.5	233.0	120.6	141.5	77.8	143.4	53.0	194.7	101.4	98.5	98.0	102.7	79.8	69.0	55.9	555.0	318.1	163.2	95.5	121.3	181.5	103.2	304.9	140.3	112.0	109.3	70.7	124.0	101.0	92.1	148.1	145.7	88.2	136.9	79.8	110.4	98.3	93.1	267.4	101.8	39.7	73.9	87.8	68.8	126.1	73.9	94.3	112.8	112.4	47.8	42.5	98.2	101.0	73.6	81.4	167.5	115.3	182.8	29.3	9.1	14.2	9.7	8.3	11.1	10.3	9.8	11.2	10.1	15.9	11.3	9.9	8.0	1.2	13.6	16.0	5.9	12.6	6.5	217.2	219.0	180.4	216.8	193.3	223.2	220.9	222.9	202.3	223.2	254.6	202.3	49.3	22.4	23.9	294.1	56.6	106.0	57.5	32.2	105.3	22.5	83.3	38.2	60.2	57.2	47.3	60.7	37.5	95.7	45.6	56.1	156.5	32.5	14.2	37.3	44.0	54.1	39.4	52.6	35.8	33.8	63.8	89.0	86.2	59.7	43.2	33.6	50.7	402.3	69.1	15.2	38.0	49.5	36.7	74.1	184.5	26.0	88.0	81.4	104.9	42.2	50.6	140.0	39.1	48.7	42.9	50.2	38.3	90.7	75.7	103.4	124.2	175.5	21.6	68.9	65.7	41.3	55.9	11.4	8.6	189.5	122.3	47.6	84.6	70.9	49.6	107.3
GLUD2	GLUDP1	ENSG00000182890	"Glutamate dehydrogenase 2"	P49448	X	121047610-121050094	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	5	"liver: 3.9;testis: 15.4"	"Cell type enhanced"	"Detected in some"		"Cardiomyocytes: 2.6;Cytotrophoblasts: 4.6;Early spermatids: 2.6;Hepatocytes: 4.6;Proximal tubular cells: 3.3"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HAP1: 3.7;K-562: 4.3;OE19: 2.1;SK-MEL-30: 5.5;THP-1: 2.7;WM-115: 6.0"									"HPA042492, HPA044839, HPA061369"	Uncertain		Approved	Mitochondria		NA	NA				"Cluster 83: Testis - Spermatogenesis"	"Cluster 17: WM-115 - Nervous system development"	"Cluster 47: Cytotrophoblasts - Unknown function"	Mitochondria		"HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494"	"unprognostic (1.44e-1)"	"unprognostic (5.49e-2)"	"unprognostic (1.90e-2)"	"unprognostic (1.39e-2)"	"unprognostic (1.27e-3)"	"unprognostic (1.29e-1)"	"unprognostic (1.77e-2)"	"unprognostic (1.24e-1)"	"unprognostic (2.23e-1)"	"unprognostic (2.42e-1)"	"unprognostic (2.61e-1)"	"unprognostic (2.35e-1)"	"prognostic favorable (1.98e-4)"	"unprognostic (1.04e-2)"	"unprognostic (1.49e-2)"	"unprognostic (4.77e-3)"	"unprognostic (5.96e-2)"	1.7	1.7	0.0	0.1	0.3	0.0	1.2	0.0	0.8	0.4	0.5	0.5	0.0	0.4	1.7	0.5	0.4	0.4	0.9	0.4	0.0	1.6	3.9	0.5	0.1	0.0	0.0	0.4	1.0	0.5	0.4	0.8	0.0	0.4	0.0	0.1	0.6	0.2	0.5	0.6	0.4	0.1	0.0	0.1	0.6	15.4	0.1	0.0	0.4	0.1	0.1	0.4	0.4	0.1	0.0	1.0	0.2	0.0	0.0	0.0	0.0	0.3	0.2	0.0	0.1	0.0	0.5	0.0	0.3	0.0	0.0	0.0	3.7	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.8	0.9	0.0	0.0	0.0	0.0	0.0	0.0	4.3	0.0	0.0	0.8	0.0	0.0	0.7	2.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.6	5.5	0.1	1.2	2.7	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.8	0.4	0.0	0.0	0.0	0.0	0.0	0.1	0.1	1.8	0.0	0.0	2.3	0.1	0.0	0.5	0.0	0.6	0.0	0.4	0.1	2.6	0.0	0.0	0.0	2.1	4.6	0.1	0.1	1.9	0.2	2.6	0.6	0.8	0.9	0.0	0.0	1.2	0.4	0.5	0.8	0.0	0.5	0.0	0.1	0.0	4.6	0.5	0.0	0.4	0.1	0.0	1.2	0.3	2.2	0.0	0.2	0.0	0.0	0.0	0.5	0.0	0.0	0.5	0.1	0.1	0.0	0.0	0.4	0.2	3.3	0.0	0.1	0.0	0.9	0.4	1.2	1.0	0.1	0.1	2.5	0.3	0.7	0.2	0.3
GMPR		ENSG00000137198	"Guanosine monophosphate reductase"	P36959	6	16238587-16295549	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Purine metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 358.6;tongue: 205.0"	"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 86.1;Endometrial ciliated cells: 118.2;Erythroid cells: 367.1;Melanocytes: 92.5"	"Cancer enhanced"	"Detected in all"		"melanoma: 95.4"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"basophil: 14.9"	"Group enriched"	"Detected in all"	6	"granulocytes: 14.9;monocytes: 5.0;NK-cells: 9.6"	"Cell line enhanced"	"Detected in many"		"HEL: 193.1;HMC-1: 314.7;SK-MEL-30: 74.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000904, HPA021476"	Uncertain					NA	NA		950000	"Cluster 34: Basophils - Unknown function"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 6: Erythroid cells - Oxygen transport"			"HPA000904: AB_1078998, HPA021476: AB_1849858"	"unprognostic (2.74e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.14e-1)"	"unprognostic (4.97e-3)"	"unprognostic (3.52e-2)"	"unprognostic (1.05e-1)"	"unprognostic (3.06e-1)"	"prognostic favorable (8.07e-4)"	"unprognostic (4.12e-1)"	"prognostic favorable (2.06e-4)"	"unprognostic (3.15e-1)"	"unprognostic (2.86e-1)"	"prognostic favorable (2.94e-5)"	"unprognostic (3.01e-1)"	"unprognostic (1.81e-1)"	"unprognostic (7.31e-2)"	"unprognostic (2.17e-1)"	10.0	23.3	28.5	2.8	31.9	29.7	6.5	32.4	21.6	6.6	35.7	15.5	2.7	13.3	16.5	5.3	56.9	3.7	101.7	19.6	38.2	25.5	5.9	9.1	2.5	36.8	45.6	38.0	18.3	14.2	24.9	7.8	35.0	63.1	3.4	2.2	21.5	9.0	358.6	12.4	6.0	9.9	39.7	12.5	36.5	52.3	41.3	6.5	4.4	205.0	1.6	5.2	3.7	33.2	0.0	0.0	0.3	0.0	2.7	2.1	0.1	3.9	15.7	27.2	55.2	1.6	0.4	0.0	8.8	6.0	19.1	0.1	6.7	0.8	4.5	0.0	5.0	193.1	0.1	0.0	11.8	0.8	314.7	3.7	2.8	8.5	0.0	22.2	49.5	0.7	43.9	0.3	4.8	3.8	0.2	4.1	2.0	0.2	7.5	0.0	41.9	0.0	36.1	5.4	9.4	1.2	1.9	3.2	74.4	12.1	3.0	1.4	12.5	0.4	0.2	1.3	7.5	2.3	0.0	0.0	0.9	20.3	21.8	14.9	3.3	0.4	0.7	5.0	1.2	0.2	0.1	0.5	1.5	1.5	0.0	0.2	3.3	9.6	1.7	1.5	0.0	16.0	28.5	31.9	32.4	21.6	19.6	38.2	36.8	45.6	35.0	39.7	41.3	33.2	4.6	0.0	0.0	8.8	1.3	5.1	30.2	0.7	0.6	0.7	5.3	3.8	52.8	35.8	2.7	20.2	0.0	25.3	0.6	1.4	86.1	12.4	16.0	118.2	8.7	6.8	7.8	367.1	3.8	4.9	2.8	10.2	9.2	78.9	55.3	38.9	17.9	5.0	8.9	0.0	11.5	3.2	4.1	6.4	2.1	16.3	34.5	47.4	92.5	2.8	9.2	9.8	2.1	3.0	1.7	3.0	1.2	80.9	1.4	69.9	2.2	15.5	6.4	0.8	0.0	12.6	7.4	6.5	17.2	1.3	1.8	6.8	3.5	19.4	3.8	8.3
GMPR2		ENSG00000100938	"Guanosine monophosphate reductase 2"	Q9P2T1	14	24232422-24239242	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Purine metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Proximal tubular cells: 123.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000904, HPA067884, HPA068782"	Approved		Approved	Nucleoplasm,Nucleoli		No	No		50000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 1: Thyroid gland - Transcription"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 39: Non-specific - Basic cellular processes"	Nucleoplasm	Nucleoli	"HPA000904: AB_1078998, HPA067884: AB_2685916, HPA068782: AB_2686032"	"unprognostic (1.95e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.34e-1)"	"unprognostic (1.03e-1)"	"unprognostic (9.86e-2)"	"unprognostic (5.98e-2)"	"unprognostic (3.24e-1)"	"unprognostic (5.21e-3)"	"unprognostic (9.24e-2)"	"unprognostic (3.08e-1)"	"unprognostic (7.88e-2)"	"unprognostic (1.16e-1)"	"prognostic favorable (2.21e-5)"	"unprognostic (2.30e-1)"	"unprognostic (1.96e-1)"	"unprognostic (2.29e-1)"	"unprognostic (1.12e-2)"	45.0	92.1	24.5	19.7	25.7	19.3	44.3	25.8	30.2	44.7	28.2	44.2	30.9	38.2	29.9	38.7	44.9	32.0	39.6	24.8	25.7	70.1	56.0	38.8	26.9	26.2	25.6	51.2	49.0	67.7	48.1	22.7	26.8	41.7	25.5	18.8	41.8	26.3	40.6	35.2	45.8	21.2	26.0	55.9	50.7	21.9	26.1	28.4	58.4	19.8	27.3	43.1	40.3	26.2	27.1	34.2	29.0	26.7	50.9	74.7	40.0	32.1	59.2	47.3	55.7	38.8	24.6	34.7	22.5	49.8	25.5	43.6	42.4	69.2	69.5	19.0	25.5	24.3	25.0	159.1	46.8	53.7	51.4	72.2	54.9	23.6	47.7	61.1	69.7	52.3	12.5	33.3	46.6	51.8	50.1	57.1	34.3	39.5	37.3	33.5	24.2	22.6	69.1	52.7	22.0	36.2	16.9	45.8	52.6	39.5	38.6	41.1	36.2	23.0	15.8	32.0	20.6	59.4	63.1	21.8	16.6	38.9	20.2	24.3	34.2	15.0	19.7	27.5	21.6	13.7	21.5	23.7	35.9	15.9	19.3	20.2	56.0	14.9	27.9	15.8	31.5	26.5	24.5	25.7	25.8	30.2	24.8	25.7	26.2	25.6	26.8	26.0	26.1	26.2	25.2	25.6	18.7	10.7	23.2	11.0	44.5	49.9	27.3	19.6	24.8	32.9	12.5	38.6	35.7	53.3	4.2	67.2	22.6	35.6	101.8	43.6	18.3	29.6	16.6	26.3	10.3	20.6	7.8	33.0	48.5	18.8	17.9	20.0	31.7	29.7	16.8	24.8	50.0	18.5	8.0	19.8	30.5	46.6	14.6	10.5	28.9	32.5	21.4	9.4	32.1	43.3	25.7	7.5	11.7	33.7	32.1	25.2	21.2	19.0	50.2	123.1	43.2	19.7	26.3	16.0	24.5	19.8	10.3	20.7	10.7	49.3	24.6	51.3	28.4	30.5
GPD1		ENSG00000167588	"Glycerol-3-phosphate dehydrogenase 1"	P21695	12	50103982-50111313	"Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 609.9;skeletal muscle: 577.1"	"Group enriched"	"Detected in many"	4	"Hepatocytes: 99.1;Proximal enterocytes: 247.0;Proximal tubular cells: 298.4"	"Cancer enhanced"	"Detected in many"		"liver cancer: 18.0"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	4	"ASC diff: 134.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA044620, HPA058621"	Enhanced					NA	NA		4700000		"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA044620: AB_10796803, HPA058621: "	"unprognostic (2.65e-2)"	"unprognostic (5.60e-2)"	"unprognostic (3.28e-2)"	"unprognostic (3.37e-2)"	"unprognostic (3.26e-1)"	"unprognostic (2.54e-1)"	"unprognostic (1.45e-3)"	"unprognostic (7.19e-2)"	"unprognostic (9.42e-2)"	"unprognostic (1.58e-1)"	"unprognostic (2.24e-2)"	"unprognostic (3.24e-1)"	"unprognostic (1.37e-1)"	"unprognostic (9.58e-2)"	"unprognostic (3.37e-1)"	"unprognostic (1.14e-1)"	"unprognostic (1.12e-2)"	609.9	4.7	9.1	1.6	16.8	0.2	229.2	22.7	12.8	0.3	5.5	6.4	76.4	0.2	5.3	4.9	0.5	16.6	9.2	10.1	14.2	149.3	147.6	18.4	1.0	32.6	18.3	0.3	7.2	13.0	1.3	0.0	26.5	1.3	3.3	1.0	33.0	1.3	577.1	10.2	76.9	1.3	32.7	0.4	3.3	0.8	18.4	1.5	2.7	215.7	0.4	4.1	1.0	49.4	0.1	0.2	0.1	0.1	134.0	0.0	0.3	0.1	0.0	0.0	0.0	27.0	0.1	0.4	0.7	0.0	0.0	0.0	0.2	0.0	0.0	0.3	0.6	0.1	0.6	25.2	0.0	0.2	0.0	0.3	0.2	0.1	0.3	0.1	0.0	0.7	0.7	0.3	0.0	0.2	0.1	0.4	0.1	3.7	0.0	0.2	0.2	30.2	0.2	0.0	0.6	0.2	0.0	1.5	1.0	0.0	1.8	0.0	0.0	0.0	0.3	0.2	0.1	0.6	0.7	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	9.1	16.8	22.7	12.8	10.1	14.2	32.6	18.3	26.5	32.7	18.4	49.4	3.4	3.2	3.2	0.0	2.4	0.0	0.2	0.3	0.6	3.2	3.4	3.7	5.8	11.5	1.8	5.5	8.4	0.0	0.0	3.0	43.0	0.9	0.1	0.5	0.1	0.2	1.2	5.3	0.2	0.7	0.0	0.8	4.1	0.2	0.0	0.1	1.1	99.1	2.3	3.3	0.2	9.7	0.0	1.0	0.4	0.0	0.0	5.2	1.8	0.0	1.0	2.8	0.0	0.0	4.0	0.6	8.0	0.0	0.0	0.1	247.0	298.4	0.4	1.7	0.0	7.0	1.1	0.0	0.0	0.8	0.4	0.0	1.2	0.0	10.6	0.2
GPD1L	KIAA0089	ENSG00000152642	"Glycerol-3-phosphate dehydrogenase 1 like"	Q8N335	3	32105689-32168709	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Brugada syndrome, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 158.4;tongue: 253.1"	"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 154.1;Distal enterocytes: 75.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"BEWO: 136.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 48: NK-cells - Unknown function"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 53: Intestinal epithelial cells - Unknown function"				"unprognostic (1.23e-1)"	"unprognostic (3.12e-2)"	"prognostic favorable (7.05e-4)"	"unprognostic (2.63e-1)"	"unprognostic (9.67e-3)"	"unprognostic (2.24e-1)"	"prognostic unfavorable (1.35e-5)"	"prognostic favorable (5.71e-5)"	"unprognostic (2.49e-2)"	"unprognostic (1.74e-1)"	"unprognostic (2.00e-1)"	"unprognostic (1.53e-1)"	"prognostic favorable (3.33e-15)"	"unprognostic (1.50e-1)"	"unprognostic (1.99e-1)"	"unprognostic (2.31e-3)"	"unprognostic (5.51e-3)"	39.0	44.7	18.2	8.3	20.1	6.9	30.6	17.2	21.2	22.8	27.1	40.1	26.5	11.6	9.8	40.9	19.1	9.2	124.8	21.2	20.5	34.2	2.8	31.3	9.0	19.2	18.6	16.6	21.6	32.8	5.9	20.8	19.3	59.9	36.7	9.8	22.0	41.2	158.4	10.3	29.0	16.6	20.5	12.8	29.7	6.1	18.3	6.8	40.3	253.1	10.2	31.0	12.9	21.9	11.1	10.0	3.5	15.3	49.3	11.9	136.1	8.8	3.1	9.2	7.1	10.7	5.2	19.4	13.2	6.2	11.3	12.6	23.4	9.3	11.6	8.3	21.4	11.3	13.2	16.8	12.4	29.4	39.3	35.5	12.1	8.9	12.5	9.4	16.3	15.7	8.0	6.1	7.3	15.1	12.6	11.0	2.1	27.6	44.8	23.1	15.7	40.0	14.6	66.8	15.1	15.0	6.7	61.1	25.0	4.8	38.7	14.1	8.6	10.5	4.9	16.3	23.6	4.3	2.0	19.3	24.0	22.3	6.0	0.5	2.8	5.7	3.3	3.2	8.0	1.5	4.1	4.0	5.6	1.2	2.5	3.7	1.4	7.4	2.1	4.4	8.8	2.8	18.2	20.1	17.2	21.2	21.2	20.5	19.2	18.6	19.3	20.5	18.3	21.9	10.2	28.9	41.8	1.3	4.1	4.6	5.3	3.5	8.6	4.1	20.3	10.7	154.1	2.8	18.6	9.2	2.1	36.4	10.8	75.2	39.2	2.0	8.0	5.3	4.4	10.5	7.8	6.9	23.1	3.7	6.1	10.5	17.3	9.2	39.3	9.8	13.2	0.7	10.0	1.7	23.7	21.3	26.4	6.3	5.7	20.7	5.9	4.4	8.8	24.4	2.3	32.9	7.2	3.0	11.1	4.3	21.6	12.8	8.7	13.8	33.9	18.4	15.0	3.9	0.0	8.0	8.7	0.8	2.1	32.3	7.0	27.1	10.4	3.3	26.9	8.5
GPD2		ENSG00000115159	"Glycerol-3-phosphate dehydrogenase 2"	P43304	2	156435290-156613735	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 151.1;Late spermatids: 95.5;Oligodendrocyte precursor cells: 148.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"classical monocyte: 3.3;eosinophil: 1.7;intermediate monocyte: 1.6;myeloid DC: 2.7;neutrophil: 1.1;non-classical monocyte: 2.3"	"Group enriched"	"Detected in many"	5	"dendritic cells: 2.7;granulocytes: 1.7;monocytes: 3.3"	"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA008012, HPA045506"	Enhanced		Supported	Mitochondria	"Intracellular and membrane"	NA	NA		620000	"Cluster 14: Monocytes - Unknown function"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 20: HeLa - Mitochondria"	"Cluster 68: Oligodendrocytes - Mixed function"	Mitochondria		"HPA008012: AB_1079013, HPA045506: AB_2679355"	"unprognostic (1.30e-1)"	"unprognostic (2.50e-1)"	"unprognostic (1.08e-1)"	"unprognostic (4.79e-3)"	"unprognostic (3.25e-1)"	"unprognostic (2.39e-2)"	"prognostic unfavorable (1.44e-4)"	"unprognostic (1.75e-1)"	"unprognostic (1.57e-1)"	"unprognostic (1.86e-1)"	"unprognostic (2.60e-3)"	"unprognostic (6.67e-2)"	"unprognostic (6.02e-3)"	"unprognostic (1.73e-1)"	"unprognostic (1.89e-1)"	"unprognostic (2.41e-1)"	"unprognostic (1.01e-2)"	8.2	5.7	13.3	8.1	17.7	13.4	16.2	15.2	18.6	10.3	6.5	18.6	14.4	6.8	5.2	20.3	18.2	8.9	6.2	19.8	16.3	8.0	3.4	11.4	7.0	13.5	16.2	8.6	6.8	20.5	5.5	6.7	13.1	10.9	18.0	9.6	14.9	7.1	24.7	12.5	15.7	6.1	14.5	8.5	17.4	5.5	18.5	6.1	12.2	14.3	8.6	14.3	9.5	13.6	39.0	27.2	15.3	24.5	32.6	39.6	0.1	48.0	31.2	32.1	38.6	53.9	35.7	8.4	31.9	27.4	13.2	44.5	28.9	44.5	41.4	23.9	9.5	6.0	46.9	0.0	12.0	11.2	12.6	19.5	15.4	55.6	27.1	20.6	24.1	3.7	12.0	1.9	41.7	24.4	0.3	1.0	28.7	15.2	31.0	12.3	9.8	9.2	41.8	50.7	27.3	9.9	45.0	34.4	30.4	25.9	10.9	30.8	22.8	5.7	26.9	26.5	36.5	1.3	0.3	0.4	32.9	3.0	47.1	0.3	3.3	1.7	0.3	1.6	0.5	0.1	0.1	0.4	2.7	0.2	0.3	0.2	1.1	0.4	2.3	0.3	0.5	1.5	13.3	17.7	15.2	18.6	19.8	16.3	13.5	16.2	13.1	14.5	18.5	13.6	12.1	19.2	12.3	151.1	7.8	20.0	23.3	24.9	21.1	5.5	23.4	12.8	13.1	7.2	19.8	22.0	6.2	9.6	6.2	52.1	1.9	9.5	84.8	12.3	6.1	11.3	17.4	6.9	27.9	13.4	15.2	9.2	30.5	23.3	12.7	13.0	10.4	3.4	21.3	5.0	46.9	17.1	10.2	18.6	18.7	95.5	12.2	21.0	24.9	61.8	10.8	4.2	4.1	148.3	48.7	16.2	17.4	7.2	5.6	66.7	16.0	3.9	18.2	11.1	0.0	8.3	12.3	2.6	3.2	41.7	21.5	11.1	7.6	7.0	19.4	77.8
GPX1		ENSG00000233276	"Glutathione peroxidase 1"	P07203	3	49357176-49358353	"Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Oxidoreductase, Peroxidase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Hofbauer cells: 3273.8;Kupffer cells: 3971.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Group enriched"	"Detected in all"	4	"dendritic cells: 1534.3;granulocytes: 1010.7;monocytes: 1337.0"	"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB011582, HPA044758"	Approved		Supported	Cytosol		NA	NA		3100000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 15: Liver - Metabolism"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 51: Myeloid cells - Hemostasis"	Cytosol		"CAB011582: AB_2112120, HPA044758: AB_2679076"	"unprognostic (1.50e-2)"	"unprognostic (4.34e-3)"	"unprognostic (1.25e-1)"	"prognostic favorable (7.78e-4)"	"unprognostic (1.26e-1)"	"unprognostic (1.83e-1)"	"unprognostic (6.73e-3)"	"unprognostic (5.03e-2)"	"unprognostic (3.40e-2)"	"unprognostic (2.48e-1)"	"unprognostic (5.46e-2)"	"unprognostic (1.53e-1)"	"unprognostic (7.64e-3)"	"unprognostic (9.14e-3)"	"unprognostic (3.16e-2)"	"unprognostic (5.72e-3)"	"unprognostic (7.64e-3)"	321.4	200.0	178.3	151.9	186.6	246.7	151.5	190.2	298.9	90.9	247.3	86.9	122.2	82.2	17.8	134.3	86.5	91.1	95.5	173.1	198.9	152.9	281.6	168.3	174.3	234.0	213.0	61.9	74.4	35.2	85.7	121.2	208.3	107.0	42.7	8.3	113.1	53.9	157.1	70.4	113.6	70.4	218.0	195.9	92.9	31.5	217.6	75.3	82.1	61.7	86.6	116.8	94.9	256.3	322.8	189.2	72.6	95.4	113.5	205.9	225.9	217.7	114.7	151.5	80.1	157.8	229.7	0.6	301.6	139.8	181.7	93.2	98.8	660.3	31.6	200.2	271.6	224.8	190.2	397.4	575.6	161.0	594.4	455.9	267.6	292.4	221.5	190.0	341.5	78.6	0.5	179.3	125.9	0.8	51.2	407.0	441.3	147.4	510.5	190.8	93.8	120.3	258.2	385.6	87.7	178.5	249.5	1.5	287.3	75.7	1.5	559.5	546.5	209.7	236.0	385.8	453.6	1.1	127.9	116.3	390.5	436.3	507.8	1010.7	1337.0	707.6	69.8	483.7	100.9	314.2	127.7	83.7	1093.1	276.8	118.4	116.2	136.4	107.4	275.8	1534.3	233.3	1401.2	178.3	186.6	190.2	298.9	173.1	198.9	234.0	213.0	208.3	218.0	217.6	256.3	0.0	109.0	323.5	6.2	148.1	249.7	432.8	985.0	92.2	32.1	0.0	0.0	0.0	220.2	616.7	0.0	10.4	499.9	491.5	229.5	0.0	0.0	300.7	0.0	0.0	227.8	251.3	364.1	12.8	0.0	830.3	131.0	73.4	0.0	480.6	0.0	585.7	888.1	3273.8	1.7	17.9	285.0	386.6	3971.6	965.7	1102.9	134.5	1305.5	273.9	41.2	828.6	63.4	138.0	8.0	7.6	0.0	179.0	67.0	82.4	481.0	349.9	0.0	490.0	14.6	210.4	150.6	151.8	12.7	169.4	112.1	154.1	278.8	112.2	0.0	367.3	517.0
GPX2	GSHPX-GI	ENSG00000176153	"Glutathione peroxidase 2"	P18283	14	64939152-64942905	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Oxidoreductase, Peroxidase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"gallbladder: 497.7;intestine: 453.8;liver: 634.0;stomach 1: 374.6;urinary bladder: 350.5"	"Cell type enhanced"	"Detected in many"		"Cholangiocytes: 386.1;Distal enterocytes: 436.6;Gastric mucus-secreting cells: 912.3;Hepatocytes: 753.4;Intestinal goblet cells: 438.6;Paneth cells: 463.0;Undifferentiated cells: 776.8;Urothelial cells: 1062.0"	"Cancer enhanced"	"Detected in many"		"colorectal cancer: 493.1"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	4	"OE19: 4748.8"	"Region enhanced"	"Detected in single"		"pons and medulla: 1.2"	"Low region specificity"	"Detected in some"			HPA003545	Enhanced		Approved	Nucleoplasm,Cytosol		NA	NA		82000	"Cluster 48: NK-cells - Unknown function"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 21: OE19 - Mitochondria"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Nucleoplasm	Cytosol	"HPA003545: AB_10962695"	"unprognostic (3.54e-1)"	"unprognostic (1.08e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.90e-3)"	"unprognostic (4.75e-3)"	"prognostic unfavorable (5.10e-4)"	"unprognostic (2.96e-2)"	"unprognostic (2.93e-2)"	"unprognostic (7.87e-2)"	"unprognostic (1.54e-2)"	"unprognostic (8.45e-2)"	"unprognostic (1.44e-1)"	"unprognostic (2.77e-2)"	"unprognostic (4.39e-2)"	"unprognostic (3.39e-2)"	"unprognostic (6.66e-4)"	"unprognostic (1.73e-2)"	1.9	0.2	0.1	53.8	0.3	0.3	5.3	0.5	0.3	23.5	0.1	333.5	96.7	0.7	1.7	187.7	4.9	497.7	0.3	0.2	0.5	30.6	634.0	2.6	0.1	0.4	0.2	0.2	24.5	0.0	1.2	0.2	0.4	43.3	453.8	0.0	71.8	24.9	0.3	25.4	175.7	9.7	0.1	0.6	374.6	2.5	0.3	3.3	0.5	0.0	1.2	350.5	108.2	0.7	0.0	1152.6	0.0	0.2	0.0	0.0	0.2	0.1	0.0	0.0	0.0	36.9	9.6	0.0	6.0	0.0	1.9	303.7	0.6	4.8	0.0	0.2	0.1	0.1	1.1	1048.6	0.0	0.1	0.4	0.0	9.7	0.0	0.0	0.1	0.0	0.1	0.0	0.3	0.0	5.6	0.6	0.3	1.3	4748.8	0.2	0.5	0.2	0.2	0.1	727.5	324.2	0.2	0.1	13.4	0.0	0.6	0.5	0.0	0.0	0.0	0.8	0.1	0.3	0.0	0.1	0.0	0.0	0.1	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.4	0.0	0.0	0.0	0.0	0.1	0.3	0.5	0.3	0.2	0.5	0.4	0.2	0.4	0.1	0.3	0.7	0.1	0.0	0.0	0.3	6.9	9.9	169.4	104.5	42.1	0.2	0.6	4.1	0.4	386.1	17.1	23.9	0.0	0.1	0.0	436.6	11.7	272.8	13.8	3.8	0.5	3.5	115.2	50.8	0.2	260.6	0.1	2.1	912.3	2.8	13.4	0.1	17.5	753.4	0.0	0.0	0.2	438.6	36.7	26.1	0.8	66.6	0.9	3.5	0.0	1.9	3.2	0.0	0.0	0.0	0.4	163.7	463.0	0.0	2.4	100.7	68.1	31.4	9.0	0.7	0.0	0.0	3.6	0.4	0.0	315.5	9.7	0.0	5.9	0.1	776.8	1062.0
GPX3		ENSG00000211445	"Glutathione peroxidase 3"	P22352	5	151020438-151028992	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"		"Oxidoreductase, Peroxidase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"kidney: 11673.5"	"Cell type enriched"	"Detected in many"	4	"Proximal tubular cells: 20125.9"	"Cancer enhanced"	"Detected in all"		"renal cancer: 605.6;thyroid cancer: 856.0"	"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in some"	5	"neutrophil: 20.7"	"Lineage enriched"	"Detected in many"	5	"granulocytes: 20.7"	"Cell line enriched"	"Detected in many"	12	"ASC diff: 7677.4"	"Region enhanced"	"Detected in all"		"hypothalamus: 239.5"	"Low region specificity"	"Detected in all"			CAB069456	Approved				"Secreted to blood"	NA	NA	5090000000	6200000000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 7: Kidney - Transmembrane transport"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"CAB069456: AB_1616682"	"unprognostic (4.03e-1)"	"unprognostic (7.35e-2)"	"unprognostic (5.05e-3)"	"unprognostic (9.01e-2)"	"unprognostic (1.41e-2)"	"unprognostic (8.13e-2)"	"unprognostic (1.39e-2)"	"unprognostic (1.62e-1)"	"unprognostic (5.75e-3)"	"unprognostic (2.70e-3)"	"unprognostic (8.17e-3)"	"unprognostic (1.14e-2)"	"unprognostic (2.95e-1)"	"prognostic unfavorable (1.65e-4)"	"unprognostic (2.14e-1)"	"unprognostic (5.11e-2)"	"unprognostic (1.26e-1)"	4524.7	443.8	57.8	75.4	68.3	7.9	3188.6	62.7	73.8	917.6	578.2	741.2	88.3	416.0	90.7	568.6	1038.4	136.4	2362.4	68.2	117.5	11673.5	986.3	2471.8	133.2	317.7	104.5	517.8	257.0	112.4	793.7	592.2	136.6	557.5	93.4	4204.9	481.4	140.0	847.9	669.7	720.6	61.0	67.5	555.7	641.1	80.4	135.8	26.8	3627.5	458.9	44.9	1196.7	891.7	70.3	2.2	10.0	8.5	2.7	7677.4	6.7	9.2	3.5	0.8	7.9	2.4	177.5	3.9	1.1	214.1	5.6	3.2	2.8	39.6	433.2	6.0	6.1	2.5	1.9	4.3	195.0	294.7	0.5	4.3	649.1	41.2	0.2	1.0	10.6	11.3	1.2	1.2	0.3	11.0	31.4	0.5	1.2	13.8	0.8	0.2	1.0	5.2	1.7	74.1	4.3	11.3	11.4	1.2	31.6	1.9	33.6	43.5	2.1	2.5	2.3	19.6	3.7	1.0	2.7	15.6	2.5	7.0	3.0	0.6	0.0	4.3	0.1	0.0	1.6	0.3	0.0	0.0	0.0	4.2	0.0	0.0	0.0	20.7	0.0	0.2	0.0	0.0	1.6	57.8	68.3	62.7	73.8	68.2	117.5	317.7	104.5	136.6	67.5	135.8	70.3	353.6	9.6	33.7	1.0	106.8	18.5	86.9	94.8	1.2	26.3	31.7	5.5	639.8	18.6	58.3	649.2	43.8	713.8	2.2	2.3	1772.6	5.5	2.9	48.1	71.1	144.6	45.6	24.0	4.0	48.2	1191.3	514.0	50.0	627.9	11.4	274.9	735.3	228.4	151.5	16.8	0.4	5.9	91.6	47.9	86.7	17.5	446.7	160.2	23.2	3.7	0.7	5019.8	0.0	0.0	0.3	9.9	13.8	41.0	2.2	141.8	0.5	20125.9	39.1	86.8	683.7	131.6	264.6	7.1	10.3	13.9	21.6	1767.7	68.3	1.0	1.3	34.3
GPX4	"MCSP, PHGPx"	ENSG00000167468	"Glutathione peroxidase 4"	P36969	19	1103926-1106791	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		"Developmental protein, Oxidoreductase, Peroxidase"	Dwarfism	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enriched"	"Detected in all"	4	"Late spermatids: 18580.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008630, HPA047224, HPA058546"	Enhanced		Approved	Nucleoplasm,Mitochondria	"Intracellular and membrane"	NA	NA		150000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 78: Testis - Spermatogenesis"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 31: Spermatids - Spermatogenesis"	"Nucleoplasm, Mitochondria"		"CAB008630: AB_1616685, HPA047224: AB_2679990, HPA058546: AB_2683749"	"unprognostic (8.42e-3)"	"prognostic favorable (7.18e-4)"	"unprognostic (8.14e-3)"	"prognostic favorable (1.84e-5)"	"unprognostic (1.00e-1)"	"unprognostic (8.72e-2)"	"unprognostic (2.53e-3)"	"unprognostic (8.49e-2)"	"unprognostic (2.69e-2)"	"unprognostic (1.47e-1)"	"prognostic favorable (7.72e-4)"	"unprognostic (1.29e-1)"	"prognostic favorable (8.61e-4)"	"unprognostic (1.61e-2)"	"unprognostic (2.20e-1)"	"unprognostic (6.67e-3)"	"unprognostic (2.96e-2)"	927.8	535.3	415.1	127.4	428.7	178.0	733.3	440.7	519.1	280.8	478.7	249.0	259.0	188.4	318.9	220.4	199.2	196.6	426.0	419.2	450.3	536.5	687.8	307.9	216.4	430.9	448.3	260.3	157.9	285.5	398.4	147.2	454.1	322.1	110.9	167.5	304.9	193.8	672.3	290.4	236.2	87.9	418.2	213.2	219.0	1403.5	444.0	158.7	291.5	399.7	182.5	319.0	245.2	429.1	258.1	286.8	405.8	863.0	1202.1	706.0	449.3	199.3	713.5	371.1	375.9	590.5	339.8	92.8	211.8	405.8	313.5	283.1	239.7	289.3	180.5	522.3	436.5	175.0	246.9	849.2	697.4	207.6	269.4	707.3	432.1	188.3	314.7	665.9	527.1	317.5	249.4	225.7	311.1	660.4	353.8	354.9	386.2	569.7	458.9	482.8	55.3	271.3	408.9	629.9	348.3	220.6	390.5	366.1	422.1	246.7	358.1	498.0	450.9	392.3	257.4	680.6	254.6	786.5	582.0	224.3	369.4	412.2	230.9	578.9	539.6	564.4	219.8	405.4	256.9	352.7	319.7	230.7	404.0	309.9	339.4	245.0	265.1	196.6	462.2	278.8	310.3	841.7	415.1	428.7	440.7	519.1	419.2	450.3	430.9	448.3	454.1	418.2	444.0	429.1	415.9	179.5	189.7	21.2	281.7	510.0	525.8	1188.1	512.2	332.2	845.1	868.2	264.6	316.0	600.6	472.6	98.0	562.5	231.3	479.1	1592.6	515.8	4209.7	546.8	326.3	268.7	397.1	215.0	24.5	368.7	1327.3	536.1	99.9	442.3	346.1	242.6	322.0	826.2	1184.1	208.6	33.1	328.7	671.4	583.1	1304.8	18580.2	384.9	735.2	677.7	21.5	1786.8	502.6	192.6	13.6	35.4	484.0	507.9	312.9	189.2	694.7	1861.9	3024.7	800.9	246.0	243.3	244.6	587.1	1310.8	202.4	357.7	467.0	978.1	281.0	186.7	336.4	662.6
GPX5		ENSG00000224586	"Glutathione peroxidase 5"	O75715	6	28525881-28534955	"Enzymes, Metabolic proteins, Predicted secreted proteins"		"Oxidoreductase, Peroxidase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	6	"epididymis: 9.3"	"Group enriched"	"Detected in some"	46	"Early spermatids: 14.3;Late spermatids: 41.5"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"																"Secreted in male reproductive system"	NA	NA				"Cluster 68: Epididymis - Unknown function"		"Cluster 25: Spermatids - Spermatogenesis"															"unprognostic (3.34e-2)"			"unprognostic (3.74e-2)"			0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	9.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	14.3	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	41.5	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0
GPX6	GPXP3	ENSG00000198704	"Glutathione peroxidase 6"	P59796	6	28503296-28528215	"Enzymes, Metabolic proteins, Predicted secreted proteins"		"Oxidoreductase, Peroxidase"		"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at transcript level"	"Tissue enriched"	"Detected in single"	15	"epididymis: 3.3"	"Group enriched"	"Detected in some"	6	"Early spermatids: 3.3;Late spermatids: 2.8"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Region enriched"	"Detected in some"	16	"basal ganglia: 23.8"	"Low region specificity"	"Detected in single"								"Secreted in male reproductive system"	NA	NA				"Cluster 68: Epididymis - Unknown function"		"Cluster 25: Spermatids - Spermatogenesis"																		"unprognostic (2.99e-2)"			0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	3.3	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0
GPX7	"FLJ14777, GPX6, NPGPx"	ENSG00000116157	"Glutathione peroxidase 7"	Q96SL4	1	52602371-52609051	"Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins"		"Oxidoreductase, Peroxidase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Endometrial stromal cells: 43.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"fHDF/TERT166: 68.6;HEL: 63.9;REH: 76.4;RPMI-8226: 130.0;THP-1: 101.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"								"Secreted to blood"	NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 28: Placenta - Pregnancy"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 33: Fibroblasts - ECM organization"				"unprognostic (5.87e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.78e-1)"	"unprognostic (7.43e-3)"	"unprognostic (3.18e-1)"	"unprognostic (5.64e-2)"	"unprognostic (6.12e-3)"	"unprognostic (1.73e-1)"	"unprognostic (4.42e-2)"	"unprognostic (8.18e-2)"	"unprognostic (4.17e-1)"	"unprognostic (2.48e-3)"	"prognostic unfavorable (2.26e-5)"	"unprognostic (1.14e-2)"	"unprognostic (9.24e-2)"	"unprognostic (3.08e-2)"	"unprognostic (5.44e-2)"	8.4	7.9	4.8	12.4	5.0	18.3	11.9	5.2	5.4	11.6	9.3	9.4	3.3	13.1	7.3	4.3	9.1	13.4	10.8	4.6	5.9	6.9	5.3	6.8	16.5	5.2	5.1	8.9	11.5	8.5	12.5	29.3	5.0	8.7	5.5	1.7	5.9	9.7	12.1	5.0	6.0	10.8	5.0	8.1	5.0	5.5	5.0	15.9	17.1	11.5	14.0	12.4	6.9	4.9	0.1	0.0	18.1	33.9	6.6	19.1	0.1	12.5	0.7	14.8	15.3	12.2	0.0	0.1	9.8	68.6	0.0	0.0	29.0	0.0	8.1	0.0	0.2	63.9	3.6	11.3	23.9	0.0	0.0	44.4	0.0	2.5	0.0	0.0	22.9	0.4	0.0	0.0	28.2	0.0	3.3	33.5	31.5	0.0	0.0	76.4	0.0	130.0	1.3	0.0	13.7	27.0	33.3	0.0	21.9	3.0	0.0	101.1	1.4	0.0	3.7	3.8	0.1	0.1	0.0	47.9	0.0	0.2	11.3	0.2	1.7	5.4	22.6	0.4	31.8	32.0	34.6	27.1	5.4	35.2	44.5	29.0	0.9	31.6	0.2	73.7	27.6	21.4	4.8	5.0	5.2	5.4	4.6	5.9	5.2	5.1	5.0	5.0	5.0	4.9	8.4	3.2	5.5	1.0	16.1	2.2	9.0	8.3	1.2	1.0	7.1	13.6	3.9	12.8	6.5	3.7	0.0	22.8	9.2	0.2	5.9	11.1	6.9	8.2	43.7	12.4	1.2	6.7	1.6	15.6	19.8	30.5	0.5	6.5	1.3	25.8	15.4	3.8	12.3	5.0	2.7	1.2	2.0	1.9	0.7	6.6	15.2	6.0	7.2	4.7	5.0	8.3	9.2	4.5	2.0	4.7	0.7	13.5	25.2	5.7	0.0	3.0	7.0	0.6	13.1	13.3	14.5	10.8	12.1	1.9	3.3	15.6	10.9	19.3	0.6	4.9
GPX8	"EPLA847, UNQ847"	ENSG00000164294	"Glutathione peroxidase 8 (putative)"	Q8TED1	5	55160167-55167297	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Oxidoreductase, Peroxidase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Endometrial stromal cells: 62.7;Extravillous trophoblasts: 218.9;Fibroblasts: 76.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 254.4;fHDF/TERT166: 246.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA036720	Enhanced		Approved	"Plasma membrane,Actin filaments,Cytosol"		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 33: Fibroblasts - ECM organization"	"Plasma membrane, Cytosol"	"Actin filaments"	"HPA036720: AB_2675269"	"unprognostic (4.85e-2)"	"unprognostic (1.23e-2)"	"unprognostic (6.53e-2)"	"unprognostic (1.92e-2)"	"unprognostic (2.31e-2)"	"unprognostic (9.74e-3)"	"unprognostic (1.78e-2)"	"unprognostic (1.63e-3)"	"unprognostic (2.07e-2)"	"unprognostic (4.34e-2)"	"unprognostic (4.31e-2)"	"unprognostic (8.68e-2)"	"prognostic unfavorable (5.13e-9)"	"prognostic unfavorable (7.96e-4)"	"unprognostic (8.11e-2)"	"unprognostic (1.16e-2)"	"unprognostic (2.63e-2)"	13.3	6.1	1.2	12.5	1.2	0.1	12.6	1.2	1.6	37.1	6.9	7.3	2.9	21.1	21.9	6.2	14.3	17.0	11.2	1.0	1.7	6.5	2.2	6.9	3.8	1.5	1.1	27.3	4.6	9.3	2.4	39.7	1.4	10.2	8.4	1.3	7.2	15.8	1.5	5.0	4.1	27.2	1.5	4.0	5.6	5.6	1.2	1.3	22.3	6.3	3.0	17.8	9.8	3.6	37.2	39.0	75.3	77.0	180.7	223.9	36.6	179.8	254.4	97.0	192.7	3.2	82.1	0.0	199.0	246.4	86.5	28.2	46.0	51.5	131.5	0.5	17.3	2.1	49.1	6.9	64.4	0.0	0.0	157.5	60.8	68.3	35.5	126.5	122.7	0.0	1.1	0.1	137.4	14.4	0.0	0.0	32.6	1.0	42.8	0.1	40.2	0.0	65.9	1.3	0.1	1.4	56.6	4.6	68.0	80.8	56.6	3.4	102.7	63.6	65.6	84.5	102.3	0.1	0.5	0.5	103.0	0.1	118.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	1.2	1.2	1.2	1.6	1.0	1.7	1.5	1.1	1.4	1.5	1.2	3.6	10.9	0.0	1.1	0.3	0.3	7.1	6.0	38.3	9.1	0.2	8.9	6.1	4.3	0.0	33.3	25.8	0.0	49.5	0.2	0.5	5.9	13.7	0.4	6.5	62.7	18.6	0.0	0.0	0.1	38.8	218.9	76.6	2.6	4.9	4.5	30.9	19.2	0.2	10.2	0.0	0.1	4.7	4.1	0.0	6.9	0.6	51.3	1.1	24.9	5.6	1.1	7.9	0.0	0.0	0.1	15.8	0.3	39.9	1.4	2.6	0.1	0.5	36.5	0.3	13.1	20.1	38.2	0.1	0.4	3.1	6.1	13.3	1.8	29.9	0.9	2.4
GRHPR	"GLXR, PH2"	ENSG00000137106	"Glyoxylate and hydroxypyruvate reductase"	Q9UBQ7	9	37422666-37436990	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 652.5"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 864.6;Proximal tubular cells: 817.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA022971, HPA078575"	Enhanced		Approved	Nucleoplasm,Cytosol		NA	NA		2700000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 85: Liver - Metabolism"	"Cluster 20: HeLa - Mitochondria"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Cytosol	Nucleoplasm	"HPA022971: AB_1849975, HPA078575: "	"prognostic favorable (7.00e-5)"	"unprognostic (6.84e-2)"	"unprognostic (2.62e-1)"	"unprognostic (2.64e-3)"	"unprognostic (5.78e-3)"	"unprognostic (3.04e-1)"	"unprognostic (1.02e-3)"	"unprognostic (1.22e-1)"	"unprognostic (2.24e-1)"	"unprognostic (4.49e-2)"	"unprognostic (5.88e-2)"	"unprognostic (2.36e-1)"	"prognostic favorable (5.39e-9)"	"unprognostic (1.04e-1)"	"unprognostic (2.11e-1)"	"unprognostic (1.15e-1)"	"unprognostic (1.79e-1)"	58.9	143.1	72.6	35.5	83.9	40.5	55.7	84.1	74.3	53.0	76.1	60.5	63.5	58.5	62.6	62.5	51.0	36.6	107.6	69.7	76.4	156.5	652.5	42.9	55.8	76.3	76.2	63.4	64.2	49.1	35.7	35.2	77.6	50.7	35.4	20.8	74.8	46.4	168.5	64.2	51.4	42.8	75.9	41.7	60.7	37.9	78.4	34.7	43.4	146.4	51.5	52.9	51.8	89.4	111.7	157.7	87.5	81.0	80.1	86.4	87.7	86.2	114.3	115.8	125.2	60.3	47.2	106.5	50.0	105.3	85.8	49.3	51.7	113.5	69.3	140.3	62.8	61.6	144.1	107.5	124.3	58.7	61.6	104.2	97.2	67.6	87.4	98.0	102.2	67.5	116.1	42.9	104.2	85.3	58.9	60.8	53.5	101.1	67.5	55.4	62.1	59.1	155.9	63.0	36.3	64.3	74.4	143.8	84.1	79.1	80.1	75.7	109.7	63.5	100.4	44.0	76.9	33.1	27.4	70.8	90.8	33.5	95.7	45.0	64.7	33.9	39.3	66.9	32.7	61.6	40.8	44.6	70.3	65.6	39.6	33.9	14.5	64.5	56.7	63.4	57.8	52.0	72.6	83.9	84.1	74.3	69.7	76.4	76.3	76.2	77.6	75.9	78.4	89.4	50.7	57.7	30.2	24.2	37.5	43.3	52.5	87.3	41.5	39.0	53.7	65.7	103.7	177.3	53.8	51.5	20.9	152.6	33.9	65.3	248.4	78.0	14.9	38.4	65.4	47.9	62.2	54.7	10.3	89.0	93.0	67.7	52.0	44.8	50.1	93.3	67.5	864.6	110.8	23.5	11.0	79.7	71.2	82.9	45.8	16.0	74.6	49.2	80.0	14.0	71.1	102.8	33.0	16.1	44.9	73.8	56.9	98.6	30.1	46.4	135.6	817.7	36.0	29.1	78.9	54.3	71.8	22.3	19.0	74.6	56.3	88.9	32.5	233.3	80.9	48.1
GSR		ENSG00000104687	"Glutathione-disulfide reductase"	P00390	8	30678066-30727846	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase	"Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary hemolytic anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"basophil: 32.3"	"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001538, CAB008632, HPA064806"	Approved		Supported	Cytosol		NA	NA		81000000	"Cluster 46: Basophils - DNA binding"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 40: Granulosa cells - Unknown function"	Cytosol		"CAB008632: AB_1616690, HPA001538: AB_1078986, HPA064806: "	"unprognostic (1.23e-1)"	"prognostic favorable (3.37e-4)"	"prognostic favorable (4.08e-5)"	"unprognostic (2.89e-3)"	"unprognostic (1.62e-1)"	"unprognostic (3.50e-1)"	"prognostic unfavorable (3.26e-5)"	"unprognostic (3.61e-2)"	"unprognostic (1.01e-1)"	"unprognostic (4.15e-2)"	"unprognostic (2.83e-2)"	"unprognostic (6.92e-3)"	"prognostic favorable (1.80e-4)"	"unprognostic (2.31e-3)"	"unprognostic (2.26e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.29e-1)"	13.6	23.3	12.3	18.7	11.1	25.9	11.0	10.6	11.7	28.5	25.8	42.5	54.3	16.0	21.6	37.3	21.6	30.5	25.4	12.9	12.5	45.3	35.8	17.4	23.6	9.5	14.2	23.1	26.5	82.3	14.8	23.5	12.0	35.3	46.6	12.8	25.8	29.4	28.9	12.8	50.8	17.9	10.7	22.1	41.8	11.6	17.6	26.7	16.9	21.3	24.0	22.5	27.7	11.2	49.4	197.8	35.9	40.1	35.8	38.3	29.1	23.4	46.8	31.8	36.7	66.0	31.3	95.8	94.8	32.0	96.1	59.2	62.3	51.1	33.1	22.6	40.7	104.6	67.0	197.8	88.4	38.6	159.7	72.6	28.5	48.9	20.9	33.5	43.3	57.3	73.2	55.1	67.9	44.1	147.1	32.0	65.4	191.9	31.5	43.8	41.9	59.3	56.0	124.3	28.2	31.8	31.2	87.8	58.8	40.7	37.5	32.6	63.8	21.0	34.7	37.3	35.2	20.2	29.4	70.0	51.9	51.8	62.4	32.3	5.9	15.0	5.0	5.4	8.8	3.6	4.5	5.4	6.0	2.3	2.8	3.7	8.2	3.6	7.9	3.9	4.5	3.1	12.3	11.1	10.6	11.7	12.9	12.5	9.5	14.2	12.0	10.7	17.6	11.2	8.2	3.2	20.8	12.7	13.7	4.2	15.2	9.4	52.3	6.7	6.7	5.0	26.8	30.0	15.0	12.9	16.7	17.0	20.3	61.8	9.8	11.4	8.4	61.4	13.4	9.9	34.1	28.6	18.1	19.8	6.3	10.0	33.1	41.3	6.3	64.3	12.1	43.4	18.2	3.3	27.4	51.7	8.2	40.5	5.8	18.9	7.2	22.1	8.8	11.2	20.6	12.6	17.5	12.5	10.0	15.2	32.0	10.9	15.6	27.5	75.7	19.0	11.7	8.0	6.6	7.0	8.6	1.2	3.4	39.6	5.4	6.4	17.3	17.2	47.5	33.5
GSTO1	"GSTTLp28, P28"	ENSG00000148834	"Glutathione S-transferase omega 1"	P78417	10	104235356-104267459	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Oxidoreductase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 657.7"	"Cell type enhanced"	"Detected in all"		"Hofbauer cells: 676.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-MEL-30: 1106.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA037603, HPA037604"	Enhanced					NA	NA		120000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 85: Liver - Metabolism"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 51: Myeloid cells - Hemostasis"			"HPA037603: AB_2675574, HPA037604: AB_10672283"	"prognostic favorable (6.95e-4)"	"unprognostic (9.23e-2)"	"unprognostic (1.43e-2)"	"unprognostic (6.83e-2)"	"unprognostic (7.16e-2)"	"prognostic unfavorable (8.83e-4)"	"unprognostic (1.38e-2)"	"unprognostic (1.84e-1)"	"unprognostic (9.23e-3)"	"unprognostic (4.57e-2)"	"unprognostic (7.65e-2)"	"unprognostic (2.13e-1)"	"prognostic unfavorable (2.11e-4)"	"unprognostic (1.86e-2)"	"unprognostic (1.29e-1)"	"unprognostic (5.51e-3)"	"unprognostic (5.82e-2)"	95.0	145.4	119.1	102.8	123.1	191.6	89.9	121.3	166.7	90.1	118.0	92.7	167.6	72.0	96.2	79.3	75.4	84.8	277.4	117.3	124.8	154.4	657.7	154.7	93.1	121.3	127.1	83.1	80.5	129.7	102.9	113.6	122.7	80.3	94.8	38.2	75.6	89.6	148.4	63.8	165.2	86.9	122.2	107.1	93.3	14.9	128.8	124.8	82.9	122.5	77.4	109.6	82.6	136.4	287.7	194.5	142.9	249.3	201.4	385.1	62.8	358.3	640.7	237.9	257.2	247.2	292.8	254.2	152.8	245.6	296.8	158.8	97.0	329.2	244.5	128.4	233.7	186.6	122.1	542.7	359.7	241.5	294.5	291.5	136.7	346.3	414.5	331.3	464.1	231.2	394.4	153.4	511.4	159.3	188.3	330.0	130.4	308.1	134.8	136.0	94.9	108.1	358.4	185.1	72.1	88.6	117.6	81.0	1106.0	238.2	92.0	192.7	426.6	276.9	143.6	427.3	328.4	2.7	3.3	2.0	517.7	416.2	112.0	842.8	532.4	157.9	133.0	457.0	164.5	148.8	164.6	172.9	429.3	111.9	143.0	144.3	151.8	185.0	369.1	203.0	204.8	632.1	119.1	123.1	121.3	166.7	117.3	124.8	121.3	127.1	122.7	122.2	128.8	136.4	107.4	76.9	72.6	8.8	64.8	93.7	328.2	297.6	51.2	36.9	63.5	105.5	328.2	218.8	113.3	101.2	20.9	394.2	82.0	101.6	332.6	341.0	22.4	68.1	79.6	164.5	103.5	192.8	12.1	248.4	176.6	173.0	49.5	81.7	146.3	107.6	388.0	628.2	676.5	23.5	11.7	163.8	124.1	321.8	223.6	17.3	114.6	484.5	126.3	8.4	277.7	81.2	95.8	8.5	21.8	347.6	150.7	112.8	39.9	169.4	483.2	538.0	114.3	29.8	151.2	85.3	176.1	5.7	5.1	55.8	78.7	111.0	81.4	224.8	196.6	204.9
GSTO2		ENSG00000065621	"Glutathione S-transferase omega 2"	Q9H4Y5	10	104268873-104304950	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Oxidoreductase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"testis: 35.9"	"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 133.1;Early spermatids: 314.6;Late spermatids: 442.8"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 16.9;CAPAN-2: 17.1;hTCEpi: 16.2;hTERT-HME1: 18.3;OE19: 22.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in some"			HPA048141	Approved					NA	NA			"Cluster 5: Granulocytes - Unknown function"	"Cluster 22: Non-specific - Unknown function"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 34: Spermatids - Unknown function"			"HPA048141: AB_2680281"	"unprognostic (5.77e-2)"	"unprognostic (6.69e-2)"	"unprognostic (7.15e-2)"	"unprognostic (1.80e-1)"	"unprognostic (2.48e-1)"	"unprognostic (3.11e-2)"	"unprognostic (3.12e-1)"	"unprognostic (2.15e-1)"	"unprognostic (7.42e-2)"	"unprognostic (5.28e-2)"	"unprognostic (1.44e-1)"	"unprognostic (1.02e-1)"	"prognostic favorable (7.10e-7)"	"unprognostic (4.56e-2)"	"unprognostic (3.92e-2)"	"unprognostic (1.75e-2)"	"unprognostic (3.47e-1)"	0.5	3.5	5.0	0.3	5.7	2.0	5.2	3.4	5.3	4.3	0.4	4.4	2.8	2.2	4.9	11.8	4.3	1.2	0.6	4.4	4.1	14.0	2.8	2.4	0.3	2.2	2.5	5.4	16.7	5.0	14.6	1.0	2.6	8.3	3.1	6.0	7.5	3.2	1.4	14.8	3.5	1.2	1.1	0.5	10.9	35.9	4.3	2.2	7.0	1.3	0.7	3.8	7.5	5.3	10.2	1.4	0.5	0.6	0.6	1.3	1.4	9.6	16.9	4.7	4.9	0.6	17.1	1.6	4.0	0.8	0.5	10.7	0.5	5.3	1.2	1.1	3.2	0.5	3.1	2.4	2.1	0.7	0.7	1.7	16.2	0.3	18.3	1.3	0.8	1.7	1.5	2.9	1.3	12.3	0.1	0.5	1.7	22.1	1.1	0.5	0.7	0.3	4.6	6.5	0.6	1.1	3.3	2.4	2.9	0.8	12.6	0.3	2.4	1.5	5.1	0.6	0.5	2.8	6.4	0.4	1.5	0.8	0.5	0.2	0.1	0.7	0.5	0.2	0.3	0.3	0.5	0.3	0.0	0.5	0.7	0.4	1.7	1.0	0.1	0.3	1.2	0.2	5.0	5.7	3.4	5.3	4.4	4.1	2.2	2.5	2.6	1.1	4.3	5.3	3.6	3.2	21.0	13.1	1.3	34.2	62.1	94.5	50.1	19.0	61.7	78.2	3.0	21.5	46.4	40.5	16.7	14.4	3.8	12.8	133.1	30.6	314.6	26.9	7.6	5.4	54.2	3.6	33.9	63.3	9.9	4.7	31.6	37.6	2.5	3.3	15.7	3.6	1.8	0.0	28.7	34.0	50.8	1.6	3.7	442.8	2.8	2.7	17.8	1.9	2.1	11.1	1.0	24.1	20.1	31.6	29.1	9.8	0.9	25.6	27.1	43.8	31.2	23.0	6.6	3.1	7.4	22.0	8.9	46.0	47.3	6.7	4.3	11.6	40.7	58.0
H6PD	"GDH, H6PDH"	ENSG00000049239	"Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase"	O95479	1	9234774-9271337	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Carbohydrate metabolism, Glucose metabolism"	"Hydrolase, Multifunctional enzyme, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 94.5"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 164.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"ASC diff: 68.9;ASC TERT1: 78.9;HSkMC: 77.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004824, HPA005440"	Approved		Uncertain	Cytosol	"Intracellular and membrane"	NA	NA		140000000	"Cluster 7: Monocytes - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 2: Hepatocytes - Metabolism"	Cytosol		"HPA004824: AB_1079037, HPA005440: AB_1079036"	"unprognostic (4.83e-3)"	"unprognostic (3.91e-2)"	"unprognostic (1.18e-1)"	"unprognostic (3.49e-1)"	"unprognostic (5.53e-3)"	"unprognostic (2.86e-2)"	"unprognostic (8.35e-2)"	"unprognostic (5.18e-2)"	"unprognostic (9.73e-2)"	"unprognostic (1.26e-3)"	"unprognostic (2.16e-2)"	"unprognostic (7.35e-3)"	"unprognostic (8.20e-2)"	"unprognostic (3.61e-1)"	"unprognostic (1.30e-1)"	"unprognostic (8.65e-2)"	"unprognostic (1.95e-1)"	29.0	30.5	7.5	12.6	11.6	9.7	23.0	8.2	9.0	22.6	18.8	15.1	11.2	25.7	14.4	13.5	28.3	12.6	18.9	6.4	7.8	11.5	94.5	20.3	12.4	14.4	10.8	44.9	18.9	10.6	12.7	14.1	11.4	19.5	9.1	4.2	56.2	13.1	48.3	35.7	16.8	16.6	9.6	14.5	18.7	8.1	11.4	13.1	14.7	21.0	11.4	16.7	16.5	10.9	9.9	8.0	6.8	25.5	68.9	78.9	6.4	9.8	24.0	7.1	10.9	1.5	20.1	10.9	11.2	15.3	9.1	10.3	1.8	4.8	10.3	32.8	2.2	0.0	2.8	6.7	38.6	3.5	4.1	77.7	9.1	17.2	11.1	15.6	32.9	5.9	2.9	18.2	14.0	5.7	3.9	8.2	3.7	7.5	4.6	1.2	0.9	9.3	9.1	4.0	2.3	12.0	12.9	10.0	12.0	4.7	7.5	17.4	32.9	24.3	3.9	6.2	2.8	24.1	7.6	2.5	40.8	15.6	15.7	1.6	2.3	0.3	1.6	2.4	1.3	1.3	1.2	1.5	1.0	1.6	1.2	1.1	1.5	1.2	2.3	1.4	1.1	1.5	7.5	11.6	8.2	9.0	6.4	7.8	14.4	10.8	11.4	9.6	11.4	10.9	24.1	25.6	29.5	17.9	10.1	14.3	13.2	16.9	18.8	19.6	10.3	8.3	17.5	58.6	18.8	20.2	27.1	11.2	9.1	16.6	0.0	22.9	0.8	11.2	36.0	19.8	7.8	9.0	8.4	21.3	8.5	33.6	5.6	15.5	3.8	29.9	19.6	164.0	12.1	16.8	9.1	15.1	8.2	25.4	11.4	2.9	48.1	14.2	12.4	13.1	51.6	10.4	19.6	16.6	18.6	20.0	17.0	36.9	4.5	17.2	23.1	7.4	19.1	10.9	0.0	50.5	11.7	4.6	5.5	10.5	12.8	5.9	11.6	26.1	23.6	14.2
HAAO		ENSG00000162882	"3-hydroxyanthranilate 3,4-dioxygenase"	P46952	2	42767089-42792593	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Pyridine nucleotide biosynthesis"	"Dioxygenase, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	7	"liver: 295.8"	"Group enriched"	"Detected in many"	5	"Hepatocytes: 209.8;Proximal enterocytes: 236.8;Proximal tubular cells: 162.7"	"Group enriched"	"Detected in all"	5	"liver cancer: 46.5;renal cancer: 13.9"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"myeloid DC: 23.2"	"Group enriched"	"Detected in many"	5	"dendritic cells: 23.2;granulocytes: 19.2;monocytes: 17.4"	"Cell line enhanced"	"Detected in some"		"CACO-2: 14.0;Hep G2: 49.4;REH: 9.9;THP-1: 9.2"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"HPA036394, HPA042024"	Enhanced					NA	NA		580000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA036394: AB_10673131, HPA042024: AB_2677803"	"unprognostic (6.97e-3)"	"unprognostic (1.86e-2)"	"unprognostic (1.63e-2)"	"unprognostic (4.44e-2)"	"unprognostic (1.78e-1)"	"unprognostic (7.23e-3)"	"prognostic favorable (5.77e-4)"	"unprognostic (6.20e-2)"	"unprognostic (7.58e-2)"	"unprognostic (5.10e-2)"	"unprognostic (1.26e-1)"	"unprognostic (2.68e-2)"	"unprognostic (1.05e-1)"	"unprognostic (8.67e-2)"	"unprognostic (1.37e-1)"	"unprognostic (2.56e-1)"	"unprognostic (2.03e-1)"	8.7	5.4	1.8	5.9	2.1	4.1	12.9	2.1	2.5	16.0	3.3	13.2	23.1	10.5	14.5	6.0	10.6	6.1	7.0	1.8	2.3	41.8	295.8	5.7	6.1	2.0	2.5	14.0	26.3	2.9	4.5	8.5	2.3	10.1	11.6	0.3	3.8	11.3	2.4	5.0	40.8	4.7	2.1	5.4	9.6	1.8	2.1	4.0	5.8	3.2	4.5	15.8	9.0	2.3	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	2.4	4.6	14.0	0.1	0.0	0.1	0.6	0.0	0.0	4.7	0.0	0.8	0.0	1.4	5.6	0.0	49.4	0.4	1.9	0.1	2.3	0.0	0.5	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.3	0.0	0.2	2.6	0.2	0.0	9.9	1.1	0.3	0.0	0.0	0.1	0.0	0.6	1.0	0.0	1.3	0.0	9.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	1.7	0.0	7.9	17.4	19.2	0.0	10.5	0.0	3.5	0.0	0.0	23.2	3.9	0.0	0.1	5.5	0.7	2.9	7.7	0.0	5.6	1.8	2.1	2.1	2.5	1.8	2.3	2.0	2.5	2.3	2.1	2.1	2.3	2.5	0.0	1.1	3.6	3.5	4.0	6.3	2.3	14.8	0.1	2.9	7.6	0.6	14.3	1.6	1.8	0.0	1.1	2.9	18.3	17.6	7.4	0.0	0.6	8.1	1.9	6.7	12.0	3.4	13.3	0.5	18.0	1.5	0.3	30.4	1.2	4.6	209.8	21.3	0.0	2.2	14.9	0.0	13.5	4.9	0.2	12.5	8.7	5.4	8.4	8.4	3.6	1.0	5.5	1.0	4.8	28.7	10.5	0.5	2.1	236.8	162.7	0.5	0.3	13.1	37.7	13.8	0.4	0.7	6.0	4.8	1.2	1.2	2.2	25.5	2.7
HADH	"HADH1, HADHSC, SCHAD"	ENSG00000138796	"Hydroxyacyl-CoA dehydrogenase"	Q16836	4	107989714-108035174	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Oxidoreductase, Transferase"	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"tongue: 280.3"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 272.4;Proximal enterocytes: 383.0;Proximal tubular cells: 318.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA039588, HPA043888"	Enhanced		Supported	Mitochondria		No	Yes		1000000	"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria		"HPA039588: AB_10673425, HPA043888: AB_2678716"	"unprognostic (1.73e-1)"	"unprognostic (3.32e-3)"	"unprognostic (3.05e-3)"	"unprognostic (8.86e-3)"	"unprognostic (1.83e-1)"	"unprognostic (6.83e-2)"	"unprognostic (9.26e-3)"	"unprognostic (1.55e-2)"	"unprognostic (9.22e-2)"	"unprognostic (3.24e-2)"	"unprognostic (2.96e-1)"	"unprognostic (1.18e-2)"	"prognostic favorable (0.00e+0)"	"unprognostic (1.67e-1)"	"unprognostic (4.22e-2)"	"unprognostic (5.67e-2)"	"unprognostic (1.88e-2)"	143.0	54.1	23.2	20.9	23.8	27.4	74.9	24.6	26.3	37.9	33.5	101.2	84.4	49.8	24.9	34.2	56.2	24.0	175.6	22.9	27.2	140.2	225.5	22.8	22.2	24.7	26.3	54.3	42.1	40.2	18.0	13.7	26.0	35.4	90.8	10.4	55.9	42.4	249.7	28.0	89.1	72.7	26.0	18.0	60.7	27.9	24.9	76.0	37.7	280.3	28.5	34.1	28.7	28.0	32.2	27.9	64.3	46.2	149.2	48.2	27.0	43.1	68.5	49.6	48.9	21.2	60.9	185.0	23.5	38.8	34.6	42.0	85.5	64.5	55.5	49.6	37.2	39.9	50.5	48.9	24.3	88.2	17.0	50.4	34.1	35.1	32.3	41.4	34.4	127.1	53.1	98.7	57.3	58.9	163.6	36.7	29.0	147.8	30.1	113.5	84.3	89.2	54.5	129.4	73.2	43.1	41.1	161.9	45.6	37.0	77.4	70.8	20.6	35.5	18.9	48.5	26.7	52.1	63.3	80.6	47.0	60.2	27.0	0.0	11.1	11.4	17.2	14.2	22.1	31.4	19.5	20.7	36.8	27.1	22.4	22.2	1.2	36.7	20.1	41.7	17.7	16.3	23.2	23.8	24.6	26.3	22.9	27.2	24.7	26.3	26.0	26.0	24.9	28.0	17.3	28.9	33.8	11.1	25.7	15.6	54.2	65.8	41.5	6.9	46.5	56.1	225.6	52.9	48.1	35.0	4.2	41.0	18.3	164.7	160.4	43.3	196.8	41.4	22.6	17.5	32.4	65.6	15.1	32.2	44.7	28.2	52.5	26.1	10.8	63.9	21.0	272.4	116.5	6.7	18.9	93.3	36.7	37.8	11.8	108.5	46.3	25.3	21.4	12.2	15.3	26.8	8.2	9.5	9.9	23.0	100.8	35.3	32.0	33.9	383.0	318.8	70.8	6.8	39.5	21.7	38.2	22.4	20.3	64.0	18.2	17.0	19.6	66.3	194.2	49.1
HADHA	"GBP, LCEH, LCHAD, MTPA"	ENSG00000084754	"Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha"	P40939	2	26190635-26244672	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Lyase, Multifunctional enzyme, Oxidoreductase, Transferase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 502.5"	"Cell type enhanced"	"Detected in all"		"Proximal enterocytes: 527.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015536, HPA056070"	Approved		Enhanced	Mitochondria		NA	NA		470000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 45: Enterocytes - Digestion"	Mitochondria		"HPA015536: AB_1850473, HPA056070: AB_2683026"	"unprognostic (2.02e-1)"	"unprognostic (1.38e-2)"	"unprognostic (2.55e-1)"	"unprognostic (3.43e-1)"	"unprognostic (2.67e-2)"	"unprognostic (3.23e-2)"	"unprognostic (1.25e-2)"	"unprognostic (2.02e-1)"	"unprognostic (5.16e-2)"	"unprognostic (3.45e-1)"	"unprognostic (3.81e-1)"	"unprognostic (1.16e-1)"	"prognostic favorable (3.68e-5)"	"unprognostic (7.97e-2)"	"unprognostic (1.71e-1)"	"unprognostic (2.87e-3)"	"unprognostic (2.64e-2)"	105.0	125.3	57.7	31.1	60.7	46.3	94.9	65.0	69.6	72.6	59.1	108.4	115.0	61.8	30.7	90.1	60.1	32.4	330.2	52.8	61.9	99.0	156.7	66.9	35.3	64.4	62.2	77.8	101.4	95.0	57.4	39.2	64.2	60.2	76.1	14.9	77.9	33.4	502.5	95.7	106.2	57.4	61.8	68.4	93.8	49.0	62.4	46.7	59.5	300.7	58.5	79.1	73.6	67.2	105.7	88.1	58.4	90.8	221.1	139.9	51.5	80.6	84.7	78.5	67.7	114.7	104.1	71.7	50.2	138.4	78.6	66.8	103.4	152.6	72.5	139.1	103.6	103.3	86.2	197.9	73.3	132.2	69.2	142.7	101.6	112.4	109.3	82.8	127.7	70.4	140.2	133.2	101.1	128.2	63.4	137.7	50.1	77.5	134.1	52.9	128.5	143.7	90.3	125.3	41.9	85.1	94.6	104.6	102.4	44.5	52.2	125.8	127.1	48.8	70.7	69.9	58.0	44.8	86.5	113.4	77.6	150.2	56.2	22.5	84.0	33.5	31.8	92.3	39.1	40.5	36.8	38.7	80.8	31.2	42.6	40.1	20.9	38.8	86.1	31.3	50.9	89.9	57.7	60.7	65.0	69.6	52.8	61.9	64.4	62.2	64.2	61.8	62.4	67.2	122.4	89.8	99.0	47.0	101.2	89.0	137.5	139.9	97.3	35.6	89.7	96.4	349.9	82.9	128.0	77.3	52.1	182.0	95.1	242.1	131.0	120.8	39.2	73.3	121.1	99.1	91.4	155.9	22.8	108.5	94.7	96.1	100.4	85.5	139.9	140.3	84.3	185.1	163.0	20.2	28.2	156.5	89.5	136.8	106.0	74.3	92.6	145.0	81.8	12.2	170.7	65.4	93.7	30.7	37.4	90.0	195.6	84.2	90.4	76.2	527.4	182.5	84.8	62.3	52.6	129.9	109.6	147.9	54.9	136.5	103.3	129.2	100.5	154.7	216.7	104.4
HAO1	"GOX, GOX1"	ENSG00000101323	"Hydroxyacid oxidase 1"	Q9UJM8	20	7882985-7940458	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	583	"liver: 607.8"	"Cell type enriched"	"Detected in some"	22	"Hepatocytes: 301.4"	"Cancer enriched"	"Detected in some"	184	"liver cancer: 93.4"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"HPA049552, HPA072442"	Enhanced					NA	NA		240000		"Cluster 62: Liver - Hemostasis"		"Cluster 2: Hepatocytes - Metabolism"			"HPA049552: AB_2680814, HPA072442: "					"unprognostic (4.88e-2)"		"unprognostic (2.87e-3)"				"unprognostic (1.08e-2)"	"unprognostic (1.25e-1)"						0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	1.0	607.8	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.2	0.3	0.1	4.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.3	0.0	13.5	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	5.7	301.4	0.0	0.0	0.1	0.0	0.0	7.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.0
HAO2	"GIG16, HAOX2"	ENSG00000116882	"Hydroxyacid oxidase 2"	Q9NYQ3	1	119368779-119394130	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	16	"kidney: 303.7;liver: 425.6"	"Group enriched"	"Detected in some"	7	"Hepatocytes: 256.8;Proximal tubular cells: 450.1"	"Group enriched"	"Detected in some"	26	"liver cancer: 25.6;renal cancer: 11.5"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA050355			Uncertain	Vesicles,Cytosol		NA	NA				"Cluster 81: Kidney & Liver - Metabolism"		"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Cytosol	Vesicles	"HPA050355: "	"unprognostic (1.13e-1)"	"unprognostic (1.68e-2)"	"unprognostic (2.07e-1)"	"unprognostic (1.00e-1)"	"unprognostic (6.22e-2)"	"unprognostic (5.33e-3)"	"unprognostic (2.80e-2)"	"unprognostic (3.27e-1)"	"unprognostic (3.15e-1)"	"unprognostic (3.17e-1)"	"unprognostic (1.41e-1)"	"unprognostic (1.73e-1)"	"prognostic favorable (4.92e-4)"	"unprognostic (9.66e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.89e-2)"	"unprognostic (5.14e-4)"	0.0	0.6	0.2	0.1	0.6	0.0	0.6	0.1	0.6	0.0	0.0	0.2	0.1	0.0	0.2	0.0	0.0	0.0	0.1	0.2	0.0	303.7	425.6	0.0	0.3	0.2	0.0	0.0	0.1	0.0	0.0	0.3	0.2	0.1	0.1	0.0	0.0	0.0	0.0	4.4	0.1	0.0	0.1	0.4	0.2	0.1	0.3	23.3	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.3	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.6	0.1	0.6	0.2	0.0	0.2	0.0	0.2	0.1	0.3	0.0	0.0	0.0	0.0	0.0	3.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	5.7	0.0	11.0	0.0	0.0	0.0	0.0	49.0	0.0	0.0	0.0	0.0	0.6	0.0	13.5	0.1	0.0	0.0	0.5	0.0	0.0	0.0	0.1	4.2	256.8	0.1	0.0	0.1	0.0	0.0	6.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	450.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	1.3	0.1	0.0	0.0
HEPHL1	DKFZp686F22190	ENSG00000181333	"Hephaestin like 1"	Q6MZM0	11	94021354-94114208	"Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters"	"Copper transport, Ion transport, Transport"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	6	"esophagus: 4.5;lymphoid tissue: 9.5;skin 1: 3.8;vagina: 4.5"	"Cell type enriched"	"Detected in some"	5	"Basal keratinocytes: 10.5"	"Cancer enriched"	"Detected in some"	5	"head and neck cancer: 20.9"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	4	"HaCaT: 1.4;HBEC3-KT: 2.6"	"Region enriched"	"Detected in single"	12	"olfactory bulb: 1.2"	"Not detected"	"Not detected"			HPA031517	Uncertain					NA	NA		260000000		"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 28: Keratinocytes - Keratinization"			"HPA031517: AB_10603769"	"unprognostic (9.16e-2)"	"prognostic unfavorable (4.94e-4)"	"unprognostic (2.40e-1)"	"unprognostic (3.26e-6)"	"unprognostic (3.17e-1)"	"unprognostic (3.45e-1)"	"unprognostic (1.72e-2)"	"unprognostic (6.71e-2)"	"unprognostic (5.34e-1)"	"unprognostic (1.09e-1)"	"unprognostic (7.66e-2)"	"unprognostic (1.48e-1)"	"unprognostic (1.20e-2)"	"unprognostic (1.00e-1)"	"unprognostic (2.02e-1)"	"unprognostic (3.33e-1)"	"unprognostic (1.25e-1)"	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.8	0.0	0.0	0.0	0.0	0.0	4.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.5	0.0	0.0	3.8	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.2	0.0	9.5	0.0	4.5	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.5	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	1.4	0.0	2.6	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.3	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	10.5	0.0	0.6	0.0	0.0	0.1	0.0	0.3	0.0	0.0	1.8	0.0	0.6	0.0	0.1	0.0	0.0	1.4	0.0	0.1	0.1	0.0	0.4	1.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	1.2	0.0	0.0	0.0	0.3	0.6	0.0	0.0	1.8	0.0	0.0	0.0	0.0	1.5	0.8	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.6	0.0	0.0	0.1	0.0	0.0
HGD	"AKU, HGO"	ENSG00000113924	"Homogentisate 1,2-dioxygenase"	Q93099	3	120628172-120682269	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Phenylalanine catabolism, Tyrosine catabolism"	"Dioxygenase, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	8	"kidney: 200.3;liver: 752.6"	"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 103.7;Endometrial ciliated cells: 113.9;Glandular and luminal cells: 127.8;Hepatocytes: 534.7;Proximal tubular cells: 477.5"	"Cancer enriched"	"Detected in many"	4	"liver cancer: 119.8"	"Low region specificity"	"Detected in single"			"Immune cell enriched"	"Detected in single"	6	"neutrophil: 1.1"	"Lineage enriched"	"Detected in single"	6	"granulocytes: 1.1"	"Cell line enhanced"	"Detected in some"		"CACO-2: 55.8;EFO-21: 82.7;Hep G2: 186.6;OE19: 328.0;RPTEC TERT1: 212.2"	"Not detected"	"Not detected"			"Region enhanced"	"Detected in single"		"cerebellum: 1.2"	"HPA047374, HPA052359"	Enhanced		Approved	"Golgi apparatus"		NA	NA		700000	"Cluster 9: Neutrophils - Innate immune response"	"Cluster 85: Liver - Metabolism"	"Cluster 21: OE19 - Mitochondria"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	"Golgi apparatus"		"HPA047374: AB_2680019, HPA052359: AB_2681798"	"unprognostic (1.36e-1)"	"unprognostic (9.89e-2)"	"unprognostic (3.93e-2)"	"prognostic favorable (1.78e-4)"	"unprognostic (1.56e-1)"	"unprognostic (2.05e-1)"	"unprognostic (5.65e-3)"	"unprognostic (7.20e-2)"	"unprognostic (6.05e-2)"	"unprognostic (2.41e-3)"	"unprognostic (2.68e-2)"	"unprognostic (1.16e-1)"	"unprognostic (4.29e-3)"	"unprognostic (8.57e-2)"	"unprognostic (1.78e-1)"	"unprognostic (3.71e-3)"	"unprognostic (1.43e-1)"	0.4	0.3	0.4	2.5	1.9	0.5	12.5	0.6	0.8	27.4	1.5	16.7	31.6	3.1	13.0	0.4	4.2	61.7	0.3	0.5	0.4	200.3	752.6	0.8	0.4	0.4	0.4	0.2	31.2	7.0	0.2	0.2	0.4	44.5	20.3	0.7	4.2	4.2	0.1	0.9	25.6	0.5	0.4	0.6	25.5	0.1	0.5	0.7	55.1	0.2	0.1	0.2	0.1	0.6	0.0	12.3	4.6	0.0	0.0	0.0	0.6	0.0	0.1	0.0	0.0	55.8	10.7	0.1	82.7	0.1	0.1	0.0	0.1	0.0	0.0	0.0	0.0	2.3	0.2	186.6	0.0	0.4	1.0	0.0	0.2	0.1	0.0	0.1	0.1	0.4	0.0	0.3	0.5	0.0	0.0	0.2	0.3	328.0	0.0	0.1	0.3	0.1	212.2	0.0	0.2	0.2	0.2	0.9	0.0	0.0	0.2	1.0	0.6	0.1	0.9	0.2	0.1	0.0	0.3	0.5	0.2	0.8	0.0	0.1	0.1	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.0	2.3	0.4	1.9	0.6	0.8	0.5	0.4	0.4	0.4	0.4	0.4	0.5	0.6	0.1	0.0	2.0	0.3	5.9	0.0	0.4	0.6	0.0	0.3	7.5	1.7	0.3	81.5	4.9	27.6	2.1	0.0	0.3	18.5	103.7	7.2	0.2	113.9	17.1	1.2	43.8	24.0	3.2	17.8	0.0	0.4	19.4	127.8	1.3	0.0	16.4	534.7	0.2	0.0	0.6	16.0	2.0	16.1	0.0	0.0	0.0	21.3	0.0	1.9	2.0	4.2	0.0	0.0	0.5	12.1	35.6	0.0	0.0	12.9	54.6	477.5	4.1	0.2	0.0	0.2	1.1	0.1	0.0	0.0	0.0	0.0	3.8	0.4	9.1	0.4
HIBADH	NS5ATP1	ENSG00000106049	"3-hydroxyisobutyrate dehydrogenase"	P31937	7	27525442-27662883	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Branched-chain amino acid catabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 543.9;Proximal tubular cells: 355.1;Syncytiotrophoblasts: 272.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019522, HPA021002"	Enhanced					NA	NA		820000	"Cluster 27: Non-specific - Gene expression"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 39: Non-specific - Basic cellular processes"			"HPA019522: AB_1850690, HPA021002: AB_1850692"	"unprognostic (6.76e-2)"	"unprognostic (1.09e-1)"	"unprognostic (7.50e-2)"	"unprognostic (9.79e-2)"	"unprognostic (1.72e-1)"	"unprognostic (2.28e-3)"	"unprognostic (7.22e-3)"	"unprognostic (3.14e-2)"	"unprognostic (1.10e-1)"	"unprognostic (1.06e-1)"	"unprognostic (1.73e-1)"	"unprognostic (2.05e-2)"	"prognostic favorable (5.56e-11)"	"unprognostic (2.49e-2)"	"unprognostic (5.47e-2)"	"unprognostic (3.38e-2)"	"unprognostic (3.39e-2)"	62.1	79.0	15.0	11.9	18.0	7.6	56.5	18.8	18.4	37.2	27.6	33.8	35.0	35.3	11.6	20.4	41.6	28.4	66.7	13.2	18.2	160.5	197.9	20.4	15.1	16.1	17.0	33.4	34.2	97.4	14.1	47.4	16.9	44.7	34.5	31.5	45.4	42.4	117.4	13.1	32.0	37.2	15.6	18.0	34.0	26.4	17.4	21.2	54.5	203.2	14.8	33.5	18.0	17.5	74.0	46.8	31.0	50.1	89.1	109.8	29.3	44.8	83.8	46.3	52.8	27.6	85.2	29.9	38.4	81.4	79.4	67.1	34.5	66.5	67.3	20.9	34.6	14.6	73.0	114.3	73.8	22.4	16.1	101.2	54.1	34.8	120.6	112.1	61.7	35.3	59.7	29.2	117.2	31.2	21.4	34.7	30.0	110.4	56.0	21.2	31.2	33.1	106.5	43.6	28.6	31.7	93.8	173.5	77.9	76.4	75.0	48.6	40.3	28.6	49.5	47.1	31.2	51.8	39.7	17.8	41.2	67.8	85.1	5.3	17.3	8.2	16.7	22.8	22.5	18.2	18.4	19.3	19.3	16.4	24.0	19.8	3.0	22.9	22.0	9.1	13.2	17.4	15.0	18.0	18.8	18.4	13.2	18.2	16.1	17.0	16.9	15.6	17.4	17.5	17.3	9.6	6.4	56.2	14.1	21.3	43.6	51.9	17.1	15.8	58.8	28.2	105.8	58.6	37.7	47.8	4.2	181.1	8.1	23.3	543.9	35.8	58.5	22.8	28.5	21.5	15.6	33.2	64.4	29.1	138.9	44.6	43.3	27.3	2.5	12.0	25.4	149.8	53.7	23.5	85.9	28.9	40.7	28.3	10.0	62.3	44.7	18.5	65.8	51.5	11.0	34.1	8.2	147.2	131.6	28.0	24.1	36.9	20.1	46.1	58.4	355.1	50.8	11.9	46.0	31.6	35.4	35.0	44.3	22.4	15.5	272.4	15.2	77.3	38.8	47.3
HIF1AN	"DKFZp762F1811, FIH1, FLJ20615, FLJ22027"	ENSG00000166135	"Hypoxia inducible factor 1 subunit alpha inhibitor"	Q9NWT6	10	100529072-100559998	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 41.6;tongue: 40.8"	"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA048742, HPA065302, CAB069903"	Supported		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 25: Spermatids - Spermatogenesis"	Nucleoplasm	Cytosol	"CAB069903: AB_10000508, HPA048742: AB_2680507, HPA065302: AB_2685458"	"unprognostic (4.07e-2)"	"unprognostic (7.75e-2)"	"unprognostic (2.35e-2)"	"unprognostic (3.83e-2)"	"unprognostic (1.67e-2)"	"unprognostic (1.21e-1)"	"unprognostic (8.07e-3)"	"unprognostic (8.82e-2)"	"unprognostic (2.54e-1)"	"unprognostic (1.41e-3)"	"unprognostic (1.54e-2)"	"unprognostic (3.05e-2)"	"unprognostic (3.01e-2)"	"unprognostic (3.09e-2)"	"unprognostic (9.92e-2)"	"unprognostic (1.41e-1)"	"unprognostic (3.24e-2)"	6.5	8.1	6.9	7.8	6.5	6.2	6.5	6.1	7.3	6.2	5.7	7.5	7.2	7.3	7.2	7.5	6.8	6.3	12.3	6.6	6.0	7.5	5.4	5.7	7.8	6.7	7.5	10.3	8.1	12.1	6.5	6.0	6.5	7.5	6.6	9.8	6.5	8.3	41.6	10.1	7.2	7.4	6.0	6.8	6.5	13.9	7.0	9.3	5.5	40.8	9.6	7.1	5.4	6.5	13.8	14.4	19.0	19.1	28.8	11.9	16.3	14.4	34.4	20.9	24.5	22.3	11.5	14.8	12.8	21.7	15.4	15.9	16.9	13.0	22.6	16.5	10.2	14.2	12.8	17.2	14.9	17.1	17.9	11.7	12.9	20.4	22.2	29.4	11.9	19.5	6.3	8.1	23.9	14.4	18.3	11.2	6.2	11.6	6.9	13.2	23.4	7.2	14.6	18.2	7.2	11.9	12.4	7.6	13.7	15.8	25.7	9.2	10.1	10.6	13.8	10.6	14.7	10.9	11.8	11.1	17.6	13.8	8.1	13.7	7.6	15.3	7.7	10.7	7.7	7.9	8.0	7.3	7.2	6.4	7.6	7.8	8.0	9.1	13.0	2.6	9.8	8.4	6.9	6.5	6.1	7.3	6.6	6.0	6.7	7.5	6.5	6.0	7.0	6.5	7.9	0.0	6.5	11.8	16.7	11.0	11.5	16.4	13.1	17.9	12.3	8.9	40.7	14.3	11.7	11.0	16.7	27.8	16.5	15.5	9.8	17.3	21.5	9.0	11.3	12.1	13.2	16.0	12.2	13.9	17.6	10.9	11.2	8.7	6.3	20.0	8.2	10.9	14.3	25.2	11.2	12.0	8.2	18.5	6.8	49.3	11.1	10.1	3.6	11.2	23.4	15.0	27.8	11.1	12.8	17.7	11.3	12.0	11.2	11.4	20.1	20.5	11.6	23.1	6.6	12.0	16.1	48.2	26.6	11.4	11.6	32.7	14.0	14.8	13.3	10.3
HMGCR		ENSG00000113161	"3-hydroxy-3-methylglutaryl-CoA reductase"	P04035	5	75336329-75364001	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 105.7"	"Cell type enhanced"	"Detected in all"		"Glandular and luminal cells: 239.5;Theca cells: 148.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA008338, CAB016797, CAB078688"	Supported					NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 37: Intestine - Unknown function"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 44: Endometrium - Transcription"			"CAB016797: , CAB078688: AB_2665607, HPA008338: AB_10960401"	"unprognostic (5.07e-2)"	"unprognostic (1.65e-2)"	"unprognostic (3.65e-3)"	"unprognostic (1.02e-2)"	"unprognostic (1.65e-3)"	"unprognostic (1.02e-1)"	"unprognostic (1.45e-1)"	"unprognostic (4.41e-2)"	"unprognostic (5.45e-2)"	"unprognostic (1.90e-2)"	"unprognostic (1.41e-1)"	"unprognostic (3.99e-2)"	"prognostic favorable (9.42e-6)"	"unprognostic (2.44e-1)"	"unprognostic (2.55e-2)"	"unprognostic (3.64e-3)"	"unprognostic (4.37e-2)"	10.8	39.5	19.8	18.1	20.7	24.6	30.8	15.7	23.0	20.1	16.2	45.2	38.1	16.8	25.3	49.1	12.2	15.2	7.4	21.5	25.0	21.1	105.7	24.2	14.7	26.6	21.3	9.7	16.5	24.8	8.2	17.7	25.2	23.3	37.3	18.7	15.5	8.1	6.4	55.2	26.5	12.9	14.2	14.8	27.6	23.3	20.5	17.8	23.4	7.1	18.6	14.1	26.7	17.5	68.5	25.6	260.7	89.2	54.9	103.4	65.5	19.3	53.6	38.6	85.0	95.8	163.7	60.3	68.7	31.7	245.2	84.5	136.4	225.9	39.4	20.8	50.8	47.0	36.7	78.6	80.8	39.8	32.9	66.8	130.7	133.6	65.6	19.2	31.5	84.8	50.4	86.4	61.0	45.2	72.7	39.9	112.5	17.7	19.7	50.7	78.7	86.5	155.2	154.5	91.0	41.3	41.4	43.7	38.3	89.6	43.1	102.4	37.2	20.5	30.0	22.4	32.8	28.1	38.1	83.2	29.7	75.2	43.7	10.0	14.8	8.8	7.7	8.9	6.2	5.1	5.2	7.8	16.9	5.2	5.3	7.2	28.8	12.5	10.5	4.9	9.0	7.5	19.8	20.7	15.7	23.0	21.5	25.0	26.6	21.3	25.2	14.2	20.5	17.5	11.6	19.2	43.3	23.2	14.9	41.4	10.1	37.6	43.3	23.5	19.0	12.1	7.0	12.8	33.3	27.6	18.8	19.7	25.7	80.4	3.9	13.5	46.6	124.4	34.3	13.4	43.0	11.6	49.9	22.0	24.0	13.7	28.5	239.5	24.1	71.3	7.9	97.5	13.1	40.4	35.8	56.0	28.5	14.8	11.8	22.2	9.3	19.5	16.0	15.0	12.1	9.7	7.2	28.1	24.7	15.0	40.0	6.0	14.4	18.4	15.5	6.9	31.6	15.2	13.1	7.0	20.2	23.4	12.0	69.8	91.6	46.7	19.2	148.7	30.4	18.8
HMOX1	"bK286B10, HO-1"	ENSG00000100292	"Heme oxygenase 1"	P09601	22	35380361-35394214	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	Apoptosis	Oxidoreductase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	4	"lymphoid tissue: 612.2"	"Cell type enhanced"	"Detected in many"		"Endothelial cells: 327.1;Extravillous trophoblasts: 285.2;Hofbauer cells: 494.9;Kupffer cells: 954.1;Macrophages: 271.5;Syncytiotrophoblasts: 502.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"classical monocyte: 98.8;intermediate monocyte: 238.8;non-classical monocyte: 329.2"	"Lineage enriched"	"Detected in all"	7	"monocytes: 329.2"	"Cell line enhanced"	"Detected in many"		"BEWO: 869.1;GAMG: 631.2;U-138 MG: 506.2;U-87 MG: 489.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000635, CAB017444"	Enhanced		Uncertain	"Golgi apparatus,Plasma membrane"		NA	NA		170000	"Cluster 51: Monocytes - Innate immune response"	"Cluster 64: Macrophages - Immune response"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 4: Macrophages - Innate immune response"	"Golgi apparatus, Plasma membrane"		"CAB017444: AB_10617276, HPA000635: AB_1079089"	"unprognostic (3.12e-1)"	"unprognostic (1.00e-1)"	"unprognostic (9.42e-2)"	"unprognostic (6.94e-2)"	"unprognostic (5.57e-2)"	"unprognostic (2.47e-2)"	"prognostic unfavorable (1.59e-4)"	"unprognostic (7.56e-2)"	"unprognostic (1.71e-1)"	"unprognostic (4.91e-2)"	"unprognostic (1.62e-1)"	"unprognostic (2.76e-1)"	"unprognostic (1.95e-3)"	"unprognostic (1.91e-1)"	"unprognostic (4.82e-2)"	"unprognostic (2.26e-1)"	"unprognostic (7.54e-2)"	150.2	48.9	40.9	64.6	48.8	99.3	20.6	42.4	66.3	28.2	46.4	35.2	106.0	10.4	7.6	48.4	40.7	52.6	18.2	40.6	46.6	96.2	136.5	113.6	57.2	52.3	46.5	139.0	41.7	7.4	9.6	72.2	56.3	6.7	31.1	1.7	15.1	4.0	107.1	74.1	64.5	38.7	45.9	612.2	19.9	17.8	60.7	25.1	11.3	21.4	49.4	46.2	29.2	56.2	12.2	179.1	1.8	37.7	170.9	49.6	869.1	83.2	57.6	42.9	48.6	82.1	11.3	0.1	18.3	83.3	631.2	10.1	11.4	1.9	16.1	308.6	9.2	4.3	51.5	179.3	218.9	11.5	54.8	146.3	4.2	282.3	19.7	74.6	130.9	0.5	0.0	87.4	152.5	6.9	0.2	4.3	18.1	130.4	20.7	1.2	15.6	28.4	35.2	104.5	2.7	2.4	215.8	19.1	15.5	92.5	8.9	3.0	44.3	506.2	22.1	82.5	82.5	53.5	77.0	9.3	489.4	5.7	8.6	11.3	98.8	7.7	1.1	238.8	0.4	24.8	0.7	1.7	44.6	2.9	0.1	0.5	47.1	5.3	329.2	1.1	1.8	70.9	40.9	48.8	42.4	66.3	40.6	46.6	52.3	46.5	56.3	45.9	60.7	56.2	19.3	3.2	19.0	0.0	11.5	16.4	27.5	11.0	10.8	0.0	25.0	9.1	2.9	24.3	10.5	5.5	0.0	50.5	3.5	59.1	21.5	13.6	2.1	39.6	12.9	327.1	16.0	5.7	0.2	1.5	285.2	64.1	9.2	74.6	11.4	98.4	23.6	23.6	494.9	0.0	0.4	8.3	18.3	954.1	175.8	4.1	31.1	271.5	35.6	1.9	184.7	0.4	9.2	0.5	1.4	8.3	26.1	5.3	2.5	110.6	61.5	157.9	7.1	0.6	0.0	40.8	52.7	0.9	4.4	5.5	15.6	502.0	6.8	6.9	6.1	118.3
HMOX2	HO-2	ENSG00000103415	"Heme oxygenase 2"	P30519	16	4474690-4510347	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"Early spermatids: 515.3;Late spermatids: 2001.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025464, HPA040611"	Supported		Approved	Vesicles,Cytosol		NA	NA		12000	"Cluster 20: T-cells - T-cell receptor"	"Cluster 43: Testis - Unknown function"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 31: Spermatids - Spermatogenesis"	"Vesicles, Cytosol"		"CAB025464: , HPA040611: AB_10961034"	"unprognostic (3.33e-1)"	"unprognostic (3.58e-2)"	"unprognostic (1.11e-1)"	"prognostic favorable (7.91e-4)"	"unprognostic (2.74e-1)"	"unprognostic (4.27e-2)"	"unprognostic (6.23e-2)"	"unprognostic (5.77e-2)"	"unprognostic (1.43e-2)"	"unprognostic (3.60e-1)"	"unprognostic (7.74e-3)"	"unprognostic (9.87e-2)"	"prognostic favorable (8.98e-6)"	"unprognostic (3.51e-2)"	"unprognostic (4.14e-2)"	"unprognostic (1.65e-2)"	"unprognostic (2.64e-1)"	63.0	51.3	43.7	23.2	51.9	18.3	55.7	56.9	55.2	47.1	36.2	41.0	34.8	35.8	22.5	84.5	35.9	26.9	149.9	47.7	50.0	71.2	109.5	46.6	33.2	55.8	49.2	25.6	39.7	38.6	43.8	17.9	57.1	34.5	25.1	22.5	44.1	14.1	37.9	44.4	42.6	22.7	44.7	67.8	100.2	152.2	54.3	24.3	41.9	32.3	36.3	33.2	49.0	53.5	82.9	38.2	20.5	45.6	65.8	31.5	33.8	53.9	26.5	48.3	43.7	48.3	55.5	36.9	64.0	55.7	34.6	51.5	75.4	126.9	48.4	51.5	48.4	27.5	35.2	63.3	43.7	56.8	44.4	48.7	41.7	55.7	37.6	37.9	83.7	46.9	44.7	18.1	44.5	114.3	48.7	58.4	34.2	81.1	35.7	54.3	33.7	84.4	72.3	51.8	34.4	19.4	43.1	95.1	66.4	33.9	58.2	36.3	91.7	25.7	39.9	120.3	30.1	24.3	30.0	78.0	16.5	52.5	35.2	87.6	37.1	252.6	166.3	46.5	142.1	69.8	153.8	168.5	73.6	66.8	145.5	151.6	125.1	99.0	35.7	39.2	155.4	142.3	43.7	51.9	56.9	55.2	47.7	50.0	55.8	49.2	57.1	44.7	54.3	53.5	33.8	35.3	41.5	7.8	37.2	54.8	35.7	73.5	19.4	29.3	26.4	29.1	70.6	32.9	54.5	36.8	20.9	75.3	59.8	70.7	129.1	79.7	515.3	38.6	30.9	53.4	31.8	14.3	23.0	90.7	69.6	39.4	89.7	53.3	19.7	38.8	75.0	93.0	67.2	28.6	21.6	37.6	85.5	23.9	52.9	2001.6	45.4	30.6	62.2	5.6	29.3	53.9	141.1	9.5	32.9	114.9	70.7	56.1	47.1	37.7	110.8	239.3	39.9	27.8	72.3	14.6	58.0	199.7	149.8	28.2	51.6	38.4	88.3	47.4	48.9	28.7
HPD	"4-HPPD, 4HPPD, GLOD3, PPD"	ENSG00000158104	"4-hydroxyphenylpyruvate dioxygenase"	P32754	12	121839527-121863596	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Phenylalanine catabolism, Tyrosine catabolism"	"Dioxygenase, Oxidoreductase"	"Disease variant, FDA approved drug targets, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"liver: 2530.4"	"Group enriched"	"Detected in some"	9	"Hepatocytes: 1373.6;Proximal tubular cells: 2144.0"	"Cancer enriched"	"Detected in many"	100	"liver cancer: 540.9"	"Region enhanced"	"Detected in many"		"hippocampal formation: 7.8"	"Immune cell enhanced"	"Detected in some"		"eosinophil: 7.8"	"Group enriched"	"Detected in many"	4	"dendritic cells: 3.8;granulocytes: 7.8"	"Cell line enriched"	"Detected in some"	31	"Hep G2: 516.4"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA038321, HPA038322"	Enhanced		Uncertain	"Nuclear speckles"		NA	NA		26000000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	"Nuclear speckles"		"HPA038321: AB_2675957, HPA038322: AB_10670778"	"unprognostic (3.01e-2)"	"unprognostic (2.30e-1)"	"unprognostic (4.81e-3)"	"unprognostic (1.42e-3)"	"unprognostic (1.10e-2)"	"unprognostic (9.08e-2)"	"unprognostic (1.13e-2)"	"unprognostic (8.84e-2)"	"unprognostic (5.58e-2)"	"unprognostic (6.14e-3)"	"unprognostic (9.72e-3)"	"unprognostic (8.61e-3)"	"unprognostic (7.16e-2)"	"unprognostic (1.97e-1)"	"unprognostic (4.12e-1)"	"unprognostic (3.06e-2)"	"unprognostic (2.34e-1)"	2.3	5.3	0.6	0.7	0.4	0.9	4.6	3.2	0.6	2.0	119.0	1.2	0.1	4.1	0.7	0.7	6.4	1.1	3.5	7.8	0.5	531.0	2530.4	2.0	0.3	1.5	1.0	4.7	3.9	0.1	1.1	0.3	0.8	2.3	0.5	0.3	0.2	7.3	2.2	0.2	0.9	1.4	0.6	2.3	1.9	10.2	3.5	0.1	0.7	0.1	0.1	3.7	1.9	1.0	0.3	0.9	0.6	0.6	0.3	0.6	0.6	0.0	0.1	0.0	0.0	0.2	0.5	0.2	0.6	1.1	0.2	0.4	0.2	0.0	0.0	0.3	0.8	1.2	5.4	516.4	11.5	1.8	16.4	3.6	0.3	0.0	0.0	1.3	0.0	0.5	0.8	0.0	1.3	1.3	0.2	0.4	9.9	0.4	0.0	0.3	1.6	0.5	0.0	1.4	0.1	0.1	1.5	0.1	0.1	6.9	1.1	0.9	0.2	0.0	0.3	0.1	0.1	0.8	0.6	0.7	0.2	1.2	0.0	0.0	0.6	7.8	0.0	0.8	0.0	0.1	0.1	0.1	1.0	0.1	0.2	0.2	3.9	0.0	1.3	3.8	0.0	0.3	0.6	0.4	3.2	0.6	7.8	0.5	1.5	1.0	0.8	0.6	3.5	1.0	0.0	0.0	0.0	0.7	15.8	0.0	0.0	0.0	0.0	0.0	0.4	0.1	0.3	55.8	0.0	92.0	0.0	0.8	0.0	0.0	193.7	0.5	38.0	0.1	0.0	2.6	0.0	80.2	1.0	16.2	0.3	0.4	0.0	0.1	0.0	0.0	38.9	1373.6	0.3	0.0	1.0	0.0	0.0	37.8	0.3	121.0	2.5	10.8	0.0	0.0	0.4	0.0	0.0	1.5	0.7	0.2	0.0	5.3	0.0	0.0	0.0	2144.0	0.0	0.0	0.0	2.0	0.2	1.8	1.4	0.0	0.0	1.1	8.0	7.1	0.0	0.0
HPGD	SDR36C1	ENSG00000164120	"15-hydroxyprostaglandin dehydrogenase"	P15428	4	174490175-174523154	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism"	Oxidoreductase	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"stomach 1: 235.0;urinary bladder: 376.0"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 457.8;Extravillous trophoblasts: 701.7;granulocytes: 864.5;Proximal enterocytes: 500.6;Urothelial cells: 922.8"	"Cancer enhanced"	"Detected in many"		"urothelial cancer: 52.4"	"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in many"	5	"basophil: 123.7;T-reg: 45.0"	"Group enriched"	"Detected in many"	73	"granulocytes: 123.7;T-cells: 45.0"	"Cell line enhanced"	"Detected in many"		"A549: 157.8;ASC diff: 110.6;HEL: 355.0;OE19: 102.1;RT4: 565.7;SuSa: 121.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004919, HPA005679"	Enhanced		Supported	Nucleoplasm,Cytosol		No	NA		20000	"Cluster 46: Basophils - DNA binding"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 15: RT4 - Unknown function"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Cytosol	Nucleoplasm	"HPA004919: AB_1079081, HPA005679: AB_1079080"	"unprognostic (1.23e-3)"	"unprognostic (1.61e-1)"	"unprognostic (5.96e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.09e-2)"	"unprognostic (2.53e-2)"	"unprognostic (1.27e-1)"	"unprognostic (2.23e-1)"	"unprognostic (1.08e-1)"	"unprognostic (4.28e-2)"	"unprognostic (3.54e-3)"	"unprognostic (2.34e-2)"	"prognostic favorable (3.20e-4)"	"unprognostic (2.44e-1)"	"unprognostic (2.59e-1)"	"unprognostic (1.37e-4)"	"unprognostic (2.33e-2)"	9.2	16.5	1.0	11.4	0.7	2.7	159.9	0.5	1.2	32.2	8.7	60.9	152.2	45.5	36.5	81.6	13.4	24.9	1.6	1.2	2.8	60.2	210.8	91.0	5.5	1.4	2.0	1.1	2.6	85.3	2.1	99.1	1.0	10.2	57.4	1.0	7.7	4.0	2.5	39.8	117.3	63.7	0.8	10.3	235.0	1.6	2.2	12.2	1.7	3.0	26.6	376.0	83.0	0.7	0.0	157.8	0.0	0.0	110.6	5.4	0.4	0.0	0.0	0.0	0.4	45.1	0.2	0.1	0.0	0.0	0.2	14.2	16.0	0.0	0.0	0.3	2.9	355.0	10.8	0.3	0.0	2.1	0.9	5.6	2.6	0.0	0.1	0.1	0.0	22.6	0.2	0.0	0.0	0.3	1.2	0.3	1.4	102.1	7.4	16.3	0.3	1.3	36.2	565.7	0.9	0.4	0.0	1.3	3.5	121.3	0.1	0.0	0.3	0.0	0.2	0.1	0.0	28.4	0.0	0.1	0.3	0.2	0.0	123.7	0.3	16.6	9.9	0.0	15.6	0.4	5.2	4.5	0.7	0.2	1.6	4.0	1.3	1.1	0.0	0.0	45.0	3.0	1.0	0.7	0.5	1.2	1.2	2.8	1.4	2.0	1.0	0.8	2.2	0.7	3.4	16.0	33.0	0.0	4.3	17.3	80.8	6.9	45.5	3.3	14.5	6.7	0.8	35.8	23.6	22.0	0.0	48.5	38.5	457.8	21.5	7.4	1.4	5.7	5.4	18.2	8.4	17.2	0.8	94.5	701.7	25.3	196.7	36.4	864.5	1.5	13.9	245.7	21.4	0.0	9.7	60.7	0.0	14.8	19.5	0.5	19.9	29.2	76.5	5.6	2.9	0.0	10.3	0.0	4.1	42.4	254.7	0.0	50.2	76.8	500.6	131.1	4.4	0.8	0.0	2.4	3.7	0.5	1.0	53.4	22.4	56.6	42.7	65.0	58.9	922.8
HR	"ALUNC, AU"	ENSG00000168453	"HR lysine demethylase and nuclear receptor corepressor"	O43593	8	22114419-22133384	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"DNA-binding, Oxidoreductase"	"Disease variant, Hypotrichosis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 20.9;skin 1: 52.7"	"Cell type enhanced"	"Detected in many"		"Bipolar cells: 91.4;Cone photoreceptor cells: 33.3;Distal enterocytes: 27.5;Gastric mucus-secreting cells: 26.5;Paneth cells: 31.2"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"A549: 21.2;HaCaT: 81.7;OE19: 39.9;SiHa: 28.8;T-47d: 30.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA054888			Supported	Nucleoplasm		NA	NA				"Cluster 27: Brain & Skin - Unknown function"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 56: Bipolar cells - Visual perception"	Nucleoplasm		"HPA054888: AB_2682630"	"unprognostic (9.11e-2)"	"unprognostic (2.12e-2)"	"unprognostic (7.32e-2)"	"unprognostic (4.68e-3)"	"unprognostic (6.49e-2)"	"unprognostic (2.80e-1)"	"unprognostic (1.53e-2)"	"unprognostic (2.45e-1)"	"unprognostic (1.23e-1)"	"unprognostic (1.21e-1)"	"unprognostic (1.90e-1)"	"unprognostic (1.75e-1)"	"unprognostic (2.27e-2)"	"unprognostic (8.00e-3)"	"unprognostic (1.81e-1)"	"unprognostic (2.32e-1)"	"unprognostic (2.28e-2)"	2.4	1.0	4.3	1.8	6.7	0.0	2.7	7.8	14.5	3.8	0.0	9.0	4.8	1.6	0.1	20.9	1.1	1.3	2.3	3.1	4.8	0.6	0.4	0.8	0.3	11.3	9.0	0.6	0.5	0.0	2.7	0.1	12.0	3.8	3.2	1.8	5.1	4.2	0.7	52.7	4.7	1.5	2.4	0.5	7.7	5.3	8.8	0.6	4.3	0.9	1.2	3.0	11.7	11.5	1.9	21.2	0.0	0.0	0.2	0.6	0.1	0.1	0.1	0.0	0.0	0.0	2.6	0.0	20.7	1.5	1.0	81.7	0.0	2.0	0.0	0.0	0.0	0.0	17.8	0.1	4.7	0.0	0.1	4.1	12.9	0.0	1.4	1.3	0.0	2.1	0.0	0.2	0.0	12.7	1.5	0.3	0.0	39.9	16.3	1.9	0.0	0.5	0.3	5.7	1.0	4.7	28.8	6.4	6.5	0.3	30.0	0.0	0.0	0.4	17.2	0.0	0.9	0.0	0.0	0.0	0.2	0.0	7.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.3	6.7	7.8	14.5	3.1	4.8	11.3	9.0	12.0	2.4	8.8	11.5	1.9	0.0	0.0	1.3	0.0	12.0	4.5	4.3	10.8	91.4	4.0	3.9	2.7	0.0	1.4	1.8	33.3	0.1	0.1	27.5	0.0	0.1	0.3	1.6	1.2	0.6	7.8	0.0	8.7	0.7	0.2	2.1	26.5	2.1	0.0	0.3	1.8	0.3	0.0	10.1	3.9	8.1	0.0	0.0	2.1	1.9	3.4	0.1	21.4	0.0	0.0	3.2	0.0	2.0	9.2	0.3	31.2	7.2	0.0	3.0	11.0	0.1	1.3	8.8	0.0	5.8	3.3	0.1	0.3	15.5	17.8	0.8	0.3	0.2	19.5	6.8
HSD11B1	"HSD11, HSD11B, SDR26C1"	ENSG00000117594	"Hydroxysteroid 11-beta dehydrogenase 1"	P28845	1	209686178-209734949	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Lipid metabolism, Steroid metabolism"	Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	13	"liver: 968.3"	"Cell type enriched"	"Detected in many"	9	"Hepatocytes: 646.2"	"Cancer enriched"	"Detected in all"	28	"liver cancer: 197.4"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"memory CD4 T-cell: 5.6"	"Lineage enriched"	"Detected in single"	17	"T-cells: 5.6"	"Cell line enriched"	"Detected in some"	5	"ASC diff: 989.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA047729	Enhanced					NA	NA		110000	"Cluster 35: T-regs - Unknown function"	"Cluster 60: Liver - Hemostasis & Lipid metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 2: Hepatocytes - Metabolism"			"HPA047729: AB_2680135"	"unprognostic (1.08e-3)"	"unprognostic (2.13e-1)"	"unprognostic (2.32e-1)"	"unprognostic (1.40e-1)"	"unprognostic (1.57e-1)"	"unprognostic (3.68e-1)"	"unprognostic (2.02e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.30e-1)"	"unprognostic (3.63e-2)"	"unprognostic (8.35e-3)"	"unprognostic (8.69e-2)"	"prognostic unfavorable (1.97e-10)"	"unprognostic (3.41e-2)"	"unprognostic (3.91e-2)"	"unprognostic (6.45e-2)"	"unprognostic (1.59e-2)"	22.4	7.7	9.8	14.6	15.4	0.3	12.0	23.0	22.0	2.8	8.1	4.2	1.2	4.2	15.7	2.1	5.1	8.0	7.5	11.0	16.0	24.3	968.3	39.9	4.3	14.3	21.4	59.9	3.2	0.2	8.8	72.5	16.3	27.8	3.3	0.6	2.5	13.0	5.5	33.8	5.0	12.9	9.4	7.3	7.1	7.2	12.8	0.6	5.2	10.6	1.9	27.9	6.3	17.5	0.4	0.0	0.0	0.0	989.2	102.8	0.0	0.1	36.0	0.0	0.1	0.0	0.2	0.0	0.2	0.3	0.1	0.1	0.0	43.9	0.0	0.0	0.0	0.0	0.0	0.0	206.6	0.2	0.1	5.4	0.0	6.9	0.4	0.9	0.0	0.0	0.0	51.2	0.2	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.7	16.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	34.9	8.4	4.0	0.2	0.2	0.3	1.4	0.3	0.3	5.7	1.4	0.0	0.0	0.0	0.0	0.1	0.0	0.4	0.1	5.6	1.2	0.0	0.0	0.1	0.0	0.1	0.3	0.0	0.0	1.7	0.4	9.8	15.4	23.0	22.0	11.0	16.0	14.3	21.4	16.3	9.4	12.8	17.5	0.4	3.2	0.0	1.3	0.8	0.1	0.4	4.8	0.6	0.5	0.2	0.0	1.4	30.0	1.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	5.2	0.9	0.6	1.0	0.0	5.3	3.3	0.0	0.1	66.4	0.5	2.8	0.0	0.0	7.5	646.2	8.3	0.0	2.8	0.0	0.0	7.9	2.3	2.8	29.2	3.7	0.0	28.1	0.6	16.2	0.0	0.5	55.7	0.4	0.0	7.9	0.0	0.9	0.0	0.2	0.1	0.5	0.0	2.6	5.5	0.0	0.2	0.1	0.1	0.3	1.1	0.3	0.0	1.7
HSD17B1	"EDH17B2, EDHB17, HSD17, MGC138140, SDR28C1"	ENSG00000108786	"Hydroxysteroid 17-beta dehydrogenase 1"	P14061	17	42552922-42555214	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	12	"placenta: 82.3"	"Group enriched"	"Detected in many"	4	"Granulosa cells: 1574.2;Syncytiotrophoblasts: 1495.8"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enriched"	"Detected in many"	8	"BEWO: 399.0"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"HPA021032, HPA065296"	Enhanced		Supported	Cytosol		NA	NA		19000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 28: Placenta - Pregnancy"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 40: Granulosa cells - Unknown function"	Cytosol		"HPA021032: AB_1844345, HPA065296: AB_2685457"	"unprognostic (1.13e-1)"	"unprognostic (1.40e-2)"	"unprognostic (1.68e-2)"	"unprognostic (9.25e-2)"	"unprognostic (1.73e-1)"	"unprognostic (3.88e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.10e-1)"	"unprognostic (9.35e-2)"	"unprognostic (6.04e-2)"	"unprognostic (2.88e-5)"	"unprognostic (2.17e-1)"	"unprognostic (1.30e-1)"	"unprognostic (2.60e-2)"	"unprognostic (5.09e-1)"	"unprognostic (4.98e-1)"	"unprognostic (1.32e-2)"	4.4	1.9	3.8	1.7	4.2	0.8	3.0	3.9	4.6	3.0	2.7	2.2	2.1	2.1	0.7	6.0	3.2	0.5	2.1	3.8	3.5	2.4	2.0	1.5	1.0	4.8	3.5	6.8	3.0	0.6	2.4	82.3	4.4	2.6	0.1	0.6	3.7	0.5	4.4	6.3	2.1	0.2	3.2	2.0	2.2	3.8	3.9	0.4	2.8	0.0	0.4	1.7	3.1	6.1	7.0	6.0	1.8	20.2	1.0	0.3	399.0	4.3	0.0	0.0	0.0	2.9	2.8	0.1	4.0	0.2	1.8	9.7	0.7	3.9	0.0	7.6	10.7	3.7	3.8	4.3	0.9	2.7	3.9	0.9	13.2	0.5	2.7	1.5	0.1	2.6	5.7	1.2	0.0	4.8	3.2	2.3	0.4	1.4	2.8	3.9	3.0	2.5	0.5	3.4	4.3	5.6	2.4	41.4	4.2	0.9	48.5	1.1	4.3	2.7	5.4	2.4	2.7	7.7	4.6	1.5	1.9	1.9	2.8	1.0	2.2	2.5	1.1	2.4	1.3	1.2	1.4	1.1	1.3	1.4	1.0	1.0	2.2	1.6	1.5	0.9	0.8	2.0	3.8	4.2	3.9	4.6	3.8	3.5	4.8	3.5	4.4	3.2	3.9	6.1	2.3	0.0	2.2	6.5	2.2	3.1	8.0	14.9	6.2	8.3	11.6	10.7	3.0	4.3	5.3	5.5	12.5	333.0	3.3	4.7	23.5	1.7	1.4	3.3	9.3	4.2	4.2	0.8	1.4	5.6	30.4	11.6	1.5	3.8	2.5	1574.2	3.6	6.4	29.7	10.1	1.6	2.7	8.2	0.6	1.2	1.9	1.8	3.6	1.8	1.9	1.0	11.2	2.1	2.0	3.3	2.0	2.0	3.4	1.4	11.6	2.5	20.5	4.2	8.9	0.0	6.7	29.2	0.8	2.7	14.6	7.4	1495.8	2.6	30.0	2.6	10.4
HSD17B10	"17b-HSD10, ABAD, CAMR, ERAB, HADH2, MHBD, MRPP2, MRXS10, SDR5C1"	ENSG00000072506	"Hydroxysteroid 17-beta dehydrogenase 10"	Q99714	X	53431258-53434370	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism, Steroid metabolism, tRNA processing"	Oxidoreductase	"Disease variant, FDA approved drug targets, Mental retardation, Neurodegeneration"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Hepatocytes: 444.0;Proximal tubular cells: 427.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001432	Approved					NA	NA		290000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA001432: AB_1078740"	"unprognostic (1.27e-1)"	"prognostic favorable (2.80e-4)"	"unprognostic (2.60e-1)"	"unprognostic (2.15e-1)"	"unprognostic (2.10e-1)"	"unprognostic (1.30e-1)"	"unprognostic (8.37e-2)"	"unprognostic (5.24e-2)"	"unprognostic (1.02e-1)"	"unprognostic (8.64e-3)"	"unprognostic (4.08e-3)"	"unprognostic (2.04e-1)"	"unprognostic (1.95e-2)"	"unprognostic (8.38e-2)"	"unprognostic (3.07e-3)"	"unprognostic (2.92e-1)"	"unprognostic (9.51e-2)"	71.1	110.7	63.5	52.5	67.5	64.8	62.7	70.0	64.7	58.1	64.6	62.8	58.0	62.0	56.2	111.6	55.4	33.4	103.8	62.0	68.4	99.1	261.3	48.4	59.4	70.4	68.2	67.1	74.8	73.4	66.1	37.2	67.8	50.7	62.9	12.7	55.0	46.0	90.5	90.0	50.3	62.0	66.6	52.0	66.4	21.5	69.1	60.1	66.4	81.6	76.3	56.3	59.8	69.2	121.9	203.1	97.2	181.3	93.4	41.0	146.5	73.7	72.9	192.0	125.3	210.3	101.8	205.8	65.6	84.9	124.2	124.5	316.1	148.7	104.3	164.1	177.7	97.1	283.6	177.0	156.3	185.1	145.5	87.6	138.9	148.7	82.8	41.6	142.2	181.2	141.6	158.1	90.3	426.7	165.3	277.0	269.9	163.0	259.5	166.2	179.2	364.9	149.3	132.2	171.1	225.1	211.7	250.2	138.6	123.0	263.3	169.8	64.2	81.7	129.7	171.9	113.4	128.3	194.1	256.5	113.4	384.9	123.2	54.2	127.8	40.4	84.8	125.1	87.2	98.8	78.0	84.1	176.7	111.4	64.4	67.9	10.5	98.7	94.5	96.5	114.8	126.6	63.5	67.5	70.0	64.7	62.0	68.4	70.4	68.2	67.8	66.6	69.1	69.2	42.8	48.1	37.3	4.9	61.8	86.4	90.2	150.8	44.9	11.8	72.5	74.9	62.0	107.2	70.2	101.2	4.2	173.2	55.0	73.8	283.7	131.5	1.6	26.1	64.7	58.3	104.6	71.3	2.5	135.4	228.1	72.0	28.1	51.9	56.5	75.3	56.4	444.0	136.8	13.5	3.3	78.2	99.7	73.9	98.6	5.7	78.3	65.4	96.0	3.7	118.7	61.3	89.6	6.6	6.2	101.9	54.1	94.8	83.3	74.6	78.5	427.8	31.5	13.2	78.9	63.1	117.9	23.6	56.3	91.3	116.2	151.6	62.4	104.1	103.0	83.7
HSD17B11	"17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2"	ENSG00000198189	"Hydroxysteroid 17-beta dehydrogenase 11"	Q8NBQ5	4	87336515-87391188	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"intestine: 288.6;liver: 241.6"	"Cell type enhanced"	"Detected in all"		"Paneth cells: 498.6;Proximal enterocytes: 1134.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 768.7"	"Group enriched"	"Detected in all"	4	"granulocytes: 768.7;monocytes: 202.0"	"Cell line enhanced"	"Detected in many"		"CAPAN-2: 295.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA021608	Enhanced		Supported	"Lipid droplets"	"Intracellular and membrane"	NA	NA			"Cluster 5: Granulocytes - Unknown function"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 45: Enterocytes - Digestion"	"Lipid droplets"		"HPA021608: AB_1847660"	"unprognostic (4.53e-2)"	"unprognostic (1.61e-1)"	"unprognostic (2.35e-2)"	"unprognostic (4.14e-2)"	"unprognostic (9.68e-2)"	"unprognostic (1.92e-1)"	"unprognostic (3.35e-1)"	"unprognostic (3.70e-2)"	"unprognostic (1.78e-1)"	"unprognostic (8.53e-2)"	"unprognostic (1.24e-3)"	"unprognostic (1.83e-1)"	"unprognostic (2.65e-3)"	"unprognostic (5.53e-2)"	"unprognostic (2.13e-2)"	"unprognostic (2.44e-2)"	"unprognostic (1.04e-2)"	56.0	64.1	15.0	33.0	15.7	109.9	45.5	19.7	18.6	44.0	18.8	139.6	216.7	57.5	28.2	21.5	44.2	107.7	21.0	15.6	18.4	75.9	241.6	104.4	41.5	20.1	17.5	60.6	54.5	10.9	13.1	47.2	18.9	25.5	145.8	8.2	14.8	34.2	12.1	14.5	288.6	49.4	19.3	42.7	36.6	10.1	16.7	36.3	19.3	26.3	34.9	41.8	33.5	22.8	1.0	45.4	22.2	56.1	66.5	92.4	31.2	23.4	39.3	16.1	29.9	38.2	295.2	0.0	45.8	26.2	14.8	0.9	65.6	5.2	18.0	72.1	13.8	63.3	22.9	131.0	37.6	114.8	114.0	65.3	1.7	22.5	7.4	51.3	31.5	27.4	67.9	32.7	30.1	1.8	24.0	144.8	37.8	146.7	7.6	63.2	20.4	77.7	45.5	70.0	7.2	69.3	47.5	1.6	87.0	28.2	0.1	112.7	24.9	11.0	47.9	43.1	13.0	15.0	6.6	7.1	20.1	80.6	77.0	591.1	202.0	442.9	62.5	142.7	74.8	57.1	62.6	64.6	108.2	47.6	55.8	64.2	768.7	82.3	125.8	36.8	77.4	171.6	15.0	15.7	19.7	18.6	15.6	18.4	20.1	17.5	18.9	19.3	16.7	22.8	169.0	314.1	179.5	13.4	89.0	28.0	77.0	16.0	10.8	1.8	5.0	6.2	5.3	368.9	83.7	44.1	2.1	30.6	63.1	356.8	25.4	53.9	1.2	9.0	28.1	101.8	93.7	68.8	16.8	58.6	59.7	77.3	28.1	18.8	100.1	34.1	112.5	337.3	129.1	18.5	14.7	180.8	18.3	220.4	176.2	5.1	104.1	139.1	67.6	43.1	197.3	36.3	113.3	16.6	19.0	65.9	498.6	59.5	60.8	39.5	1134.9	173.6	62.2	3.9	72.3	77.9	43.0	2.7	15.4	10.4	21.5	14.9	93.8	65.4	281.0	93.9
HSD17B12	"KAR, SDR12C1"	ENSG00000149084	"Hydroxysteroid 17-beta dehydrogenase 12"	Q53GQ0	11	43680680-43856617	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA016427	Approved					NA	NA			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 15: Hepatocytes - Hemostasis"			"HPA016427: AB_1844347"	"unprognostic (1.93e-1)"	"unprognostic (1.92e-2)"	"unprognostic (1.53e-1)"	"unprognostic (1.62e-2)"	"unprognostic (1.10e-1)"	"unprognostic (1.14e-3)"	"prognostic unfavorable (2.76e-4)"	"unprognostic (2.99e-1)"	"unprognostic (3.31e-2)"	"unprognostic (9.16e-3)"	"unprognostic (5.16e-2)"	"unprognostic (7.54e-2)"	"prognostic favorable (2.10e-8)"	"unprognostic (6.87e-2)"	"unprognostic (1.49e-1)"	"unprognostic (2.43e-1)"	"unprognostic (2.28e-2)"	60.9	65.4	42.0	31.4	50.4	25.1	48.8	58.1	63.0	51.3	71.5	65.8	67.3	37.4	50.6	36.3	41.3	35.6	69.5	42.0	54.3	91.3	122.9	51.4	28.5	58.8	52.1	45.3	43.5	134.3	28.5	41.6	58.9	52.8	59.5	47.0	46.9	41.5	27.8	30.0	41.7	48.6	52.8	34.8	56.1	33.5	48.9	22.3	66.8	51.6	32.3	31.4	26.8	61.9	40.2	64.3	68.4	69.6	226.8	211.5	45.0	96.7	97.8	67.3	73.0	75.7	80.7	97.4	69.4	91.5	111.7	151.6	48.7	125.5	82.6	19.0	89.2	46.4	28.3	66.2	114.6	132.3	125.4	131.1	93.6	68.1	193.6	85.9	96.1	60.4	43.9	157.9	59.4	22.9	38.6	63.1	126.0	49.9	45.3	63.9	102.3	110.8	129.5	95.9	24.5	56.5	132.0	110.7	100.2	64.6	80.2	112.5	92.4	73.9	28.3	189.3	117.6	81.6	110.3	58.3	78.5	25.0	55.4	8.8	13.4	7.0	12.1	14.8	13.5	12.7	9.6	10.5	21.3	15.2	15.6	13.9	11.2	16.4	8.2	18.4	6.2	11.6	42.0	50.4	58.1	63.0	42.0	54.3	58.8	52.1	58.9	52.8	48.9	61.9	73.6	64.1	111.1	96.6	45.4	31.7	47.1	92.8	57.5	77.1	46.1	36.4	80.7	74.4	81.4	51.5	77.2	60.4	30.6	82.2	27.4	100.2	61.8	36.9	47.5	70.9	138.2	40.8	126.9	82.3	42.1	59.7	60.6	37.0	155.9	37.3	76.1	214.0	63.5	121.1	155.6	75.5	87.5	50.9	43.7	24.1	34.2	45.3	39.2	59.0	37.2	128.2	30.9	128.7	97.5	71.4	62.5	56.8	61.4	61.3	54.2	50.1	75.8	67.8	78.9	45.4	60.2	17.5	14.5	66.0	45.7	74.8	29.4	95.5	115.5	48.6
HSD17B14	"DHRS10, retSDR3, SDR47C1"	ENSG00000087076	"Hydroxysteroid 17-beta dehydrogenase 14"	Q9BPX1	19	48813018-48836510	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Lipid metabolism, Steroid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 78.2;Hofbauer cells: 149.9;Proximal tubular cells: 434.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Group enriched"	"Detected in many"	7	"B-cells: 3.7;NK-cells: 4.7;T-cells: 3.1"	"Cell line enhanced"	"Detected in many"		"GAMG: 53.9;HHSteC: 49.5;hTERT-RPE1: 37.9;Karpas-707: 50.7;RT4: 40.5"	"Not detected"	"Not detected"							HPA021467	Approved					NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 35: Non-specific - Unknown function"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA021467: AB_1847652"	"unprognostic (2.03e-1)"	"unprognostic (7.94e-3)"	"prognostic unfavorable (4.39e-5)"	"unprognostic (4.32e-2)"	"unprognostic (8.03e-2)"	"unprognostic (1.47e-1)"	"unprognostic (7.54e-2)"	"unprognostic (7.76e-3)"	"unprognostic (2.71e-1)"	"unprognostic (4.04e-1)"	"prognostic favorable (2.87e-5)"	"unprognostic (4.56e-1)"	"unprognostic (5.50e-3)"	"unprognostic (9.05e-3)"	"unprognostic (1.01e-1)"	"unprognostic (5.51e-2)"	"unprognostic (1.81e-2)"	9.2	39.5	38.1	3.2	36.3	1.2	11.2	42.8	47.7	34.1	72.5	10.5	3.3	31.6	5.6	4.2	22.7	11.6	8.1	37.2	38.2	58.2	78.8	13.1	8.0	35.6	41.2	56.2	6.2	46.7	24.1	7.3	35.3	15.0	1.9	10.0	6.4	9.2	1.3	7.7	8.2	8.5	35.8	8.7	8.6	4.8	43.6	9.6	25.3	2.2	3.8	15.8	14.6	37.0	0.1	14.0	14.1	2.4	15.8	2.6	0.3	2.6	19.9	1.1	1.2	13.4	0.2	8.0	14.2	0.6	53.9	0.1	1.3	0.1	1.3	0.5	1.0	4.1	0.3	1.8	49.5	0.0	20.9	19.0	0.5	1.2	0.5	37.9	18.1	4.8	0.1	50.7	0.1	0.5	1.1	0.4	1.2	8.2	9.3	7.9	0.1	1.5	0.0	40.5	3.5	9.0	0.0	1.8	10.9	6.0	0.4	0.5	0.0	0.3	5.2	0.5	0.1	8.9	18.9	0.6	11.9	1.2	0.1	0.0	0.0	0.0	0.9	0.0	1.5	3.7	1.5	0.7	0.0	2.5	3.1	2.3	0.0	4.7	0.0	0.5	0.5	0.8	38.1	36.3	42.8	47.7	37.2	38.2	35.6	41.2	35.3	35.8	43.6	37.0	3.3	3.2	11.5	21.5	6.0	2.5	3.6	1.7	0.0	5.5	1.3	5.0	2.0	1.5	4.4	7.3	0.0	1.4	0.3	0.0	78.2	1.9	0.4	0.3	3.5	8.2	13.2	5.3	5.0	1.1	3.0	14.1	2.0	0.7	7.0	7.4	28.5	32.0	149.9	11.8	5.0	0.3	8.2	13.4	9.5	1.4	4.1	17.3	21.4	6.5	8.0	53.5	1.0	4.5	0.8	2.6	0.0	7.2	0.1	3.8	2.2	434.5	0.7	1.6	0.0	2.4	2.9	5.6	15.7	0.3	1.8	2.2	2.8	7.5	0.2	2.9
HSD17B2	"HSD17, SDR9C2"	ENSG00000086696	"Hydroxysteroid 17-beta dehydrogenase 2"	P37059	16	82035004-82098534	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	4	"intestine: 429.0;liver: 217.9;placenta: 381.8"	"Cell type enhanced"	"Detected in many"		"Cholangiocytes: 155.8;Distal enterocytes: 203.4;Hepatocytes: 121.9;Paneth cells: 284.2;Proximal enterocytes: 390.7"	"Group enriched"	"Detected in many"	4	"liver cancer: 10.9;pancreatic cancer: 6.5;stomach cancer: 4.2;urothelial cancer: 5.6"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"BJ hTERT+: 57.9;Hep G2: 47.5;hTERT-HME1: 27.1;OE19: 87.1;RT4: 96.8;TIME: 54.0"	"Group enriched"	"Detected in some"	5	"midbrain: 2.2;pons and medulla: 3.4"	"Not detected"	"Not detected"			"HPA021826, HPA050235"	Enhanced		Approved	"Endoplasmic reticulum"		NA	NA				"Cluster 86: Liver & Placenta - Transport via ER"	"Cluster 21: OE19 - Mitochondria"	"Cluster 45: Enterocytes - Digestion"	"Endoplasmic reticulum"		"HPA021826: AB_10961148, HPA050235: AB_2681059"	"unprognostic (1.50e-1)"	"unprognostic (2.53e-2)"	"unprognostic (1.42e-1)"	"unprognostic (6.48e-2)"	"unprognostic (2.58e-1)"	"unprognostic (1.77e-1)"	"unprognostic (4.29e-2)"	"unprognostic (2.60e-1)"	"unprognostic (7.35e-2)"	"unprognostic (6.05e-3)"	"unprognostic (4.98e-2)"	"unprognostic (7.35e-2)"	"unprognostic (6.31e-4)"	"unprognostic (5.39e-2)"	"unprognostic (1.14e-1)"	"unprognostic (4.30e-2)"	"prognostic favorable (3.83e-4)"	1.6	0.0	0.4	4.2	0.2	0.7	26.4	0.9	0.4	4.3	0.2	74.8	429.0	1.2	0.1	9.6	0.1	21.1	0.2	0.3	0.2	9.6	217.9	2.3	0.3	0.1	0.0	0.3	23.2	0.0	1.2	381.8	0.1	2.0	56.9	17.4	22.1	0.2	0.1	4.2	188.6	2.4	0.0	0.2	20.1	0.3	0.1	0.4	0.1	0.0	3.4	78.6	1.4	0.3	0.4	0.1	0.4	0.0	0.0	0.7	0.7	0.2	57.9	0.0	0.0	10.9	1.7	0.1	11.4	0.0	0.1	0.4	0.0	2.4	0.0	0.1	0.1	0.3	0.3	47.5	0.4	0.3	0.3	0.0	3.1	0.0	27.1	0.6	0.9	0.1	0.1	0.4	8.6	0.1	0.0	0.9	0.2	87.1	21.4	0.1	0.2	1.3	1.0	96.8	0.4	1.5	0.0	2.7	0.2	0.0	0.1	0.1	54.0	0.6	0.5	0.3	0.0	0.2	0.2	0.3	0.0	0.2	0.0	0.3	0.1	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.1	0.5	0.1	0.1	0.2	0.0	0.0	0.4	0.2	0.9	0.4	0.3	0.2	0.1	0.0	0.1	0.0	0.1	0.3	1.0	3.2	3.9	0.3	0.7	0.4	2.7	16.4	2.2	0.5	45.7	12.3	0.6	155.8	21.4	0.0	0.0	2.7	0.3	203.4	0.0	73.6	0.5	5.9	5.4	21.3	3.0	2.7	0.1	6.0	1.8	38.3	15.3	41.3	0.0	0.0	2.5	121.9	3.5	0.0	0.1	26.3	6.1	3.1	0.0	0.9	0.0	0.4	1.8	0.0	0.0	45.1	0.0	0.0	0.1	20.1	284.2	0.0	0.1	2.7	390.7	1.4	5.6	0.7	0.0	0.4	2.0	0.0	0.1	0.8	1.1	6.4	0.7	0.0	47.1	14.8
HSD17B3	SDR12C2	ENSG00000130948	"Hydroxysteroid 17-beta dehydrogenase 3"	P37058	9	96235306-96302176	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase	"Disease variant, Pseudohermaphroditism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 15.1;testis: 36.7"	"Group enriched"	"Detected in some"	6	"Leydig cells: 108.1;Oligodendrocytes: 93.2"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HBEC3-KT: 2.3;HEL: 1.0;U-2 OS: 4.4"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA056833	Enhanced		Approved	Vesicles		NA	NA				"Cluster 78: Testis - Spermatogenesis"	"Cluster 9: U-2 OS - Unknown function"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	Vesicles		"HPA056833: AB_2683252"	"unprognostic (2.78e-1)"	"unprognostic (6.61e-3)"	"unprognostic (1.03e-1)"	"unprognostic (5.76e-2)"	"unprognostic (1.15e-1)"	"unprognostic (1.55e-1)"	"unprognostic (3.08e-2)"	"unprognostic (6.15e-2)"	"unprognostic (1.74e-1)"	"unprognostic (5.13e-2)"	"unprognostic (3.26e-4)"	"unprognostic (3.45e-1)"	"unprognostic (5.48e-8)"	"unprognostic (8.47e-3)"	"unprognostic (1.15e-1)"	"unprognostic (7.24e-2)"	"unprognostic (3.11e-2)"	1.6	0.8	3.1	0.2	4.3	0.0	1.7	3.4	5.9	3.1	2.4	2.7	0.5	1.5	0.9	0.7	3.5	0.2	2.1	3.1	3.6	4.7	15.1	1.8	0.0	4.3	3.9	1.4	4.2	0.0	1.7	0.1	4.2	3.2	0.1	0.7	1.0	0.1	0.5	0.9	3.7	0.0	3.3	0.9	1.4	36.7	4.2	0.1	10.0	0.1	0.0	1.6	1.8	5.4	0.0	0.0	0.0	0.1	0.0	0.4	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	2.3	0.0	0.0	0.0	1.0	0.0	0.1	0.2	0.0	0.0	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.3	0.1	0.1	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	4.4	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	3.1	4.3	3.4	5.9	3.1	3.6	4.3	3.9	4.2	3.3	4.2	5.4	0.0	0.0	0.0	15.3	0.2	0.0	0.1	0.8	0.0	0.2	0.1	0.0	0.6	0.0	0.2	0.0	0.0	0.0	0.0	0.4	0.0	0.2	4.0	0.2	0.0	0.4	1.8	0.0	0.5	0.4	0.0	0.1	0.0	0.2	0.0	0.0	0.0	2.5	0.0	0.0	0.5	0.5	0.0	0.0	0.4	14.4	108.1	1.1	0.0	4.7	0.1	0.6	0.0	1.0	93.2	0.2	0.1	12.8	0.0	0.1	0.6	0.0	0.5	0.2	0.0	0.1	0.5	1.9	1.8	0.0	0.3	0.1	0.0	0.0	0.3	0.0
HSD17B4	"DBP, MFE-2, SDR8C1"	ENSG00000133835	"Hydroxysteroid 17-beta dehydrogenase 4"	P51659	5	119452473-119637199	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Isomerase, Lyase, Oxidoreductase"	"Deafness, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 320.0"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 225.1;Oligodendrocytes: 221.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"basophil: 75.5"	"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA021302, HPA021311, HPA021479"	Enhanced		Enhanced	Peroxisomes		NA	NA		450000	"Cluster 2: Granulocytes - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	Peroxisomes		"HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352"	"unprognostic (1.03e-1)"	"unprognostic (1.05e-1)"	"prognostic favorable (1.33e-4)"	"unprognostic (3.21e-2)"	"unprognostic (1.24e-2)"	"unprognostic (3.12e-2)"	"unprognostic (2.83e-3)"	"unprognostic (5.47e-2)"	"unprognostic (1.54e-1)"	"unprognostic (2.03e-2)"	"unprognostic (1.02e-1)"	"unprognostic (3.85e-1)"	"prognostic favorable (6.31e-6)"	"unprognostic (1.60e-1)"	"unprognostic (8.26e-2)"	"unprognostic (1.80e-1)"	"unprognostic (6.65e-3)"	74.4	85.0	37.2	41.9	50.2	19.7	44.4	51.1	50.0	68.8	47.2	64.5	79.3	34.1	53.0	50.9	39.1	52.5	68.6	34.9	50.7	84.4	320.0	75.6	33.2	50.6	49.5	34.8	55.2	75.5	26.5	53.4	49.2	56.8	65.9	27.2	44.9	79.0	59.8	51.8	87.6	39.5	44.7	36.6	53.8	20.9	49.9	31.9	133.9	52.8	39.7	57.7	31.5	56.3	68.8	59.8	104.1	143.7	261.8	120.3	57.9	63.4	80.3	57.3	103.0	49.4	112.8	84.4	128.0	70.6	81.0	68.7	77.0	144.4	84.3	94.6	79.8	118.1	62.0	96.9	65.8	38.0	169.9	110.0	56.3	64.9	54.7	69.3	103.9	59.4	41.0	48.9	64.2	64.0	59.2	23.6	82.1	161.1	43.1	68.7	103.0	104.8	92.2	192.7	81.1	70.6	149.0	23.4	78.7	93.3	88.7	68.2	67.6	52.7	38.1	66.5	53.1	26.3	55.3	32.6	63.7	104.4	56.7	75.5	27.3	49.9	6.5	15.5	7.3	11.1	5.8	5.3	21.3	10.3	5.5	5.2	4.9	6.9	17.1	13.8	4.1	12.2	37.2	50.2	51.1	50.0	34.9	50.7	50.6	49.5	49.2	44.7	49.9	56.3	38.9	73.7	125.2	47.3	28.2	14.9	42.5	43.2	24.5	19.7	31.1	22.1	76.4	64.3	52.3	36.8	14.6	64.3	19.1	40.0	84.1	39.9	8.8	29.0	48.9	32.3	33.0	42.1	92.9	35.8	29.3	35.6	48.4	35.8	68.4	25.3	32.2	225.1	77.9	15.2	102.8	45.8	22.4	51.8	13.8	13.4	34.5	46.7	8.8	49.6	85.7	47.3	9.2	78.4	221.5	20.5	29.6	51.1	23.1	24.8	85.7	65.4	33.8	18.6	6.6	29.2	32.2	30.6	22.7	34.7	17.2	65.0	15.7	57.2	55.3	39.7
HSD17B6	"HSE, RODH, SDR9C6"	ENSG00000025423	"Hydroxysteroid 17-beta dehydrogenase 6"	O14756	12	56752161-56787790	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Lipid metabolism, Steroid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	26	"liver: 1804.3"	"Cell type enriched"	"Detected in many"	11	"Hepatocytes: 1969.3"	"Cancer enriched"	"Detected in many"	5	"liver cancer: 170.3"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in many"		"Karpas-707: 13.4;U-266/84: 18.0"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA059141	Enhanced		Approved	Nucleoplasm,Vesicles		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 62: Liver - Hemostasis"	"Cluster 16: U-266 - Nucleosome"	"Cluster 2: Hepatocytes - Metabolism"	"Nucleoplasm, Vesicles"		"HPA059141: AB_2683922"	"unprognostic (7.70e-2)"	"unprognostic (8.76e-2)"	"unprognostic (5.08e-2)"	"unprognostic (1.92e-2)"	"unprognostic (2.01e-1)"	"unprognostic (3.79e-2)"	"prognostic favorable (6.32e-4)"	"unprognostic (1.06e-2)"	"unprognostic (3.21e-1)"	"unprognostic (1.44e-1)"	"unprognostic (1.35e-1)"	"unprognostic (6.74e-2)"	"unprognostic (2.50e-10)"	"unprognostic (1.26e-1)"	"unprognostic (1.79e-1)"	"unprognostic (1.08e-1)"	"unprognostic (1.05e-1)"	8.5	2.5	13.1	6.9	16.2	0.5	0.7	13.4	18.9	28.0	9.4	24.7	3.2	20.9	1.6	9.9	6.5	9.1	0.8	12.3	12.6	2.5	1804.3	63.2	0.8	12.0	14.6	6.0	0.6	0.5	0.6	5.4	11.5	51.2	7.6	0.8	0.4	69.2	0.4	1.2	4.8	13.1	12.4	47.5	5.7	23.3	13.7	0.9	31.4	0.5	0.9	36.7	14.6	12.8	0.3	0.8	1.9	0.4	1.9	1.4	2.3	4.1	3.5	1.9	1.9	0.4	0.4	12.0	1.7	0.5	0.5	0.3	6.1	1.1	1.1	7.7	2.2	3.7	1.2	0.6	1.2	1.9	6.0	1.0	0.4	1.2	0.6	0.6	0.0	10.3	1.1	13.4	0.9	2.4	5.6	1.3	7.5	0.7	0.7	7.4	0.8	2.9	0.2	1.4	11.0	2.3	2.0	3.6	0.9	0.7	0.6	1.5	0.3	0.9	0.8	4.0	1.0	11.7	18.0	7.8	1.3	6.9	0.6	0.0	0.0	0.0	1.0	0.2	1.2	0.7	0.8	0.8	0.2	0.3	1.1	0.7	0.0	0.0	0.5	0.7	1.0	0.3	13.1	16.2	13.4	18.9	12.3	12.6	12.0	14.6	11.5	12.4	13.7	12.8	0.4	173.1	130.6	21.2	6.1	1.3	3.1	0.6	0.6	0.4	0.7	0.6	0.2	27.1	9.3	0.0	0.0	1.4	0.4	0.0	0.0	0.1	4.6	0.7	3.5	1.3	0.0	29.5	1.4	0.0	2.6	5.0	0.0	0.1	0.0	1.6	26.0	1969.3	0.4	0.0	2.1	0.4	0.0	40.2	0.3	4.5	12.5	0.5	0.0	1.0	1.0	1.3	0.0	3.0	5.5	0.1	0.0	1.5	0.8	16.1	0.0	0.3	1.5	0.6	13.1	0.6	3.5	16.4	11.4	1.2	1.6	0.4	2.2	36.0	0.7	1.1
HSD17B7	"PRAP, SDR37C1"	ENSG00000132196	"Hydroxysteroid 17-beta dehydrogenase 7"	P56937	1	162790702-162812817	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 30.2"	"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA047496	Approved					NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 85: Liver - Metabolism"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 15: Hepatocytes - Hemostasis"			"HPA047496: AB_2680068"	"unprognostic (2.93e-1)"	"unprognostic (1.36e-2)"	"unprognostic (6.03e-2)"	"unprognostic (1.12e-1)"	"unprognostic (2.34e-1)"	"unprognostic (1.63e-3)"	"unprognostic (2.57e-1)"	"unprognostic (2.51e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.38e-1)"	"unprognostic (1.94e-1)"	"unprognostic (1.37e-1)"	"prognostic unfavorable (8.47e-5)"	"unprognostic (6.25e-2)"	"unprognostic (1.90e-1)"	"unprognostic (6.35e-2)"	"unprognostic (3.17e-2)"	4.3	16.1	3.3	5.1	3.1	2.8	8.2	3.0	6.0	5.6	3.8	6.4	6.7	4.0	7.2	8.9	5.1	4.2	3.5	2.9	4.0	5.2	30.2	7.6	8.3	3.8	3.7	6.8	5.3	5.1	7.7	4.6	3.9	5.9	8.0	4.0	6.2	3.5	6.0	7.6	6.6	4.4	3.3	5.6	5.9	2.6	3.7	8.1	6.1	2.8	8.1	5.5	5.6	3.7	12.6	12.2	32.4	13.8	18.4	18.3	20.2	4.6	15.9	9.4	19.0	17.0	35.7	29.6	10.6	4.4	58.3	19.1	30.6	43.4	9.9	12.4	15.5	7.7	8.2	26.8	15.2	13.9	12.7	11.6	23.5	36.8	11.6	7.4	15.7	19.4	14.5	19.0	8.3	8.9	17.7	13.7	20.5	24.4	15.3	9.5	19.3	18.5	33.3	19.5	27.6	14.6	8.0	7.7	7.9	27.5	12.3	17.1	9.8	4.4	10.2	6.7	10.0	11.2	12.7	29.4	6.6	1.2	11.1	21.7	6.7	12.1	13.6	6.8	14.8	12.6	10.1	13.7	6.9	11.9	12.9	12.4	5.5	8.2	8.5	10.0	17.9	12.2	3.3	3.1	3.0	6.0	2.9	4.0	3.8	3.7	3.9	3.3	3.7	3.7	8.8	0.0	25.5	22.5	22.6	11.0	19.5	48.3	35.9	23.6	24.9	11.9	2.4	12.8	26.1	11.0	62.6	17.2	19.9	14.9	3.9	16.9	2.0	9.4	7.9	12.0	6.0	4.2	8.4	27.1	15.1	13.1	8.6	9.3	5.1	32.8	8.9	62.0	13.4	11.8	9.1	14.5	18.3	5.0	16.9	1.9	6.8	12.2	17.8	5.6	10.6	14.3	16.5	12.5	22.6	15.0	17.9	7.2	18.1	19.0	12.1	10.2	19.9	44.1	0.0	5.9	10.5	4.9	6.6	15.6	12.6	19.2	23.5	34.1	11.6	12.6
HSD17B8	"D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1"	ENSG00000204228	"Hydroxysteroid 17-beta dehydrogenase 8"	Q92506	6	33204655-33206831	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 125.2;Proximal tubular cells: 137.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"RPMI-8226: 79.5;T-47d: 62.0;U-266/70: 65.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA042132	Enhanced					NA	NA		97000	"Cluster 35: T-regs - Unknown function"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA042132: AB_10793978"	"prognostic favorable (9.99e-4)"	"unprognostic (4.24e-1)"	"unprognostic (2.43e-1)"	"unprognostic (1.48e-1)"	"unprognostic (2.10e-1)"	"unprognostic (8.11e-2)"	"prognostic favorable (1.90e-5)"	"unprognostic (1.50e-3)"	"unprognostic (3.12e-1)"	"unprognostic (1.34e-2)"	"unprognostic (1.58e-1)"	"unprognostic (1.89e-1)"	"prognostic favorable (2.18e-12)"	"unprognostic (2.82e-2)"	"unprognostic (5.57e-1)"	"unprognostic (3.09e-1)"	"unprognostic (3.23e-2)"	9.6	24.6	10.1	6.5	10.5	9.7	17.0	9.9	11.3	13.7	10.9	18.0	19.7	7.2	29.4	25.5	23.6	7.9	20.3	9.6	10.8	30.7	67.4	11.2	10.5	11.3	11.9	8.6	55.3	42.2	14.1	5.6	12.3	11.3	16.2	11.8	25.1	16.5	20.8	25.9	18.8	7.3	11.4	12.1	15.1	5.9	10.8	13.3	32.9	25.0	15.1	9.8	12.8	11.3	7.0	15.0	6.8	9.3	2.3	4.4	1.3	0.8	4.7	0.1	0.1	5.8	17.5	45.4	11.2	1.2	2.2	29.1	7.2	11.7	1.0	8.6	0.0	2.6	14.0	27.1	20.0	0.0	3.8	5.0	28.9	0.2	49.4	0.4	2.1	13.6	0.3	46.2	4.1	9.4	31.2	1.3	2.1	23.3	2.9	11.0	1.2	79.5	27.8	1.3	12.1	7.6	2.9	34.3	7.6	4.6	62.0	1.8	1.3	0.7	7.3	0.6	0.4	65.5	42.4	16.6	3.1	1.0	1.7	0.1	5.8	2.0	18.7	13.4	30.0	16.6	24.0	29.2	11.6	13.1	26.4	28.5	0.7	16.8	14.6	20.8	21.8	26.7	10.1	10.5	9.9	11.3	9.6	10.8	11.3	11.9	12.3	11.4	10.8	11.3	12.5	19.2	21.6	3.3	18.6	29.7	28.3	55.0	21.6	12.4	31.3	34.8	31.8	48.6	25.9	22.0	6.2	29.9	9.7	21.2	125.2	27.9	6.3	20.0	6.0	10.1	18.0	12.8	0.3	32.4	12.9	9.1	16.3	13.7	7.0	9.8	10.0	83.2	17.4	1.7	0.5	26.6	20.3	10.3	16.4	18.1	7.5	7.9	49.8	1.0	8.1	32.6	6.2	1.0	0.7	21.9	21.1	6.0	47.6	15.4	74.8	137.2	33.3	14.8	0.0	11.3	9.8	8.1	8.5	40.0	37.2	17.4	18.0	29.8	44.4	31.5
HSD3B1	"HSD3B, HSDB3, SDR11E1"	ENSG00000203857	"Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1"	P14060	1	119507198-119515054	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid metabolism, Steroid metabolism, Steroidogenesis"	"Isomerase, Multifunctional enzyme, Oxidoreductase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	9	"placenta: 77.7"	"Group enriched"	"Detected in some"	8	"Extravillous trophoblasts: 140.8;Syncytiotrophoblasts: 502.0"	"Cancer enriched"	"Detected in single"	4	"urothelial cancer: 1.6"	"Region enhanced"	"Detected in some"		"basal ganglia: 1.0;cerebral cortex: 1.0"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	6	"CACO-2: 64.1;SuSa: 26.5"									"HPA043261, HPA043264, HPA044028"	Supported		Approved	"Nucleoli,Endoplasmic reticulum,Cytokinetic bridge"		Yes	NA				"Cluster 28: Placenta - Pregnancy"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"	"Nucleoli, Endoplasmic reticulum"	"Cytokinetic bridge"	"HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781"			"unprognostic (1.53e-1)"				"unprognostic (7.11e-2)"					"unprognostic (1.15e-1)"		"unprognostic (1.04e-1)"			"prognostic favorable (4.59e-5)"	0.1	1.2	0.2	0.0	1.0	0.0	1.5	0.0	1.0	0.0	0.0	0.3	0.0	0.2	0.0	0.0	0.0	0.1	0.0	0.3	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	77.7	0.0	0.1	0.5	0.0	0.1	0.0	0.1	4.5	8.7	0.5	0.0	0.2	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.7	0.2	0.0	0.0	0.0	64.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.8	0.0	0.0	0.0	0.0	0.0	3.9	0.0	0.0	7.0	0.7	0.8	26.5	0.0	0.0	0.2	0.0	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	1.0	0.0	1.0	0.3	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	23.6	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.2	0.0	140.8	0.8	0.0	0.0	0.0	0.0	0.0	0.0	7.1	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	5.0	0.0	0.0	0.0	37.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	502.0	0.0	0.1	1.0	0.0
HSD3B2	SDR11E2	ENSG00000203859	"Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2"	P26439	1	119414931-119423035	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	Steroidogenesis	"Isomerase, Multifunctional enzyme, Oxidoreductase"	"Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	56	"adrenal gland: 2174.8"	"Group enriched"	"Detected in some"	4	"Granulosa cells: 40.6;Proximal enterocytes: 38.8;Theca cells: 68.9"	"Cancer enhanced"	"Detected in single"		"testis cancer: 0.6"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"SK-MEL-30: 1.4"									"HPA043261, HPA043264, HPA044028"	Supported		Uncertain	"Nucleoli,Endoplasmic reticulum,Cytokinetic bridge"		Yes	NA				"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 52: Non-specific - Transcription"	"Nucleoli, Endoplasmic reticulum"	"Cytokinetic bridge"	"HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781"	"unprognostic (3.56e-1)"		"unprognostic (1.85e-1)"		"unprognostic (2.80e-1)"		"unprognostic (2.72e-2)"		"unprognostic (8.87e-2)"	"unprognostic (3.91e-2)"	"unprognostic (3.43e-2)"	"unprognostic (1.94e-1)"	"unprognostic (6.51e-2)"	"unprognostic (1.97e-2)"	"unprognostic (1.55e-1)"			0.2	2174.8	0.3	2.1	0.8	0.0	0.1	0.0	0.7	0.2	0.0	7.7	0.0	0.2	0.0	0.2	0.4	0.0	0.3	0.2	0.0	0.9	1.0	0.5	0.0	0.0	0.0	0.9	0.5	0.0	0.1	3.6	0.1	0.4	1.0	0.0	1.0	0.0	0.1	0.2	38.7	0.1	0.0	0.2	0.3	2.9	0.2	0.5	0.2	0.0	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.4	0.0	0.0	1.4	0.5	0.0	0.0	0.3	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.2	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.8	0.0	0.7	0.2	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	11.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.3	0.1	3.5	0.0	0.0	0.0	40.6	0.0	0.0	0.1	0.0	0.0	2.1	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	2.6	0.0	0.0	38.8	0.4	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.1	0.0	68.9	1.7	0.0
HSD3B7	"C(27)-3BETA-HSD, SDR11E3"	ENSG00000099377	"Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7"	Q9H2F3	16	30985207-30989147	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	Steroidogenesis	Oxidoreductase	"Disease variant, Intrahepatic cholestasis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	5	"liver: 136.5"	"Cell type enhanced"	"Detected in many"		"Ductal cells: 42.5;Hepatocytes: 68.9;Hofbauer cells: 53.9;Proximal enterocytes: 45.3;Proximal tubular cells: 46.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	27	"basophil: 61.8;eosinophil: 27.3"	"Lineage enriched"	"Detected in many"	38	"granulocytes: 61.8"	"Cell line enhanced"	"Detected in many"		"HDLM-2: 91.0;Hep G2: 66.2;HMC-1: 98.1;U-2197: 96.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015965, HPA050521, HPA060847"	Approved		Enhanced	"Lipid droplets"		NA	NA			"Cluster 2: Granulocytes - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 50: Fibroblasts - ECM organization"	"Lipid droplets"		"HPA015965: , HPA050521: AB_2681155, HPA060847: AB_2684379"	"unprognostic (5.41e-3)"	"unprognostic (4.14e-3)"	"prognostic unfavorable (5.95e-4)"	"unprognostic (2.62e-2)"	"unprognostic (5.06e-3)"	"unprognostic (1.47e-2)"	"unprognostic (3.52e-2)"	"unprognostic (1.85e-1)"	"unprognostic (2.04e-2)"	"unprognostic (1.76e-1)"	"unprognostic (3.20e-2)"	"unprognostic (2.81e-1)"	"prognostic unfavorable (1.60e-6)"	"unprognostic (2.45e-1)"	"unprognostic (1.12e-1)"	"unprognostic (1.58e-1)"	"unprognostic (1.79e-1)"	27.3	25.7	5.7	10.9	6.2	4.4	17.1	14.7	9.1	8.5	3.5	15.9	19.5	9.5	2.1	12.3	9.4	11.5	11.7	5.9	5.9	27.7	136.5	11.2	8.4	6.3	5.4	8.6	25.6	8.0	5.4	4.5	6.6	8.2	5.8	1.6	10.0	4.5	7.0	18.5	18.4	9.8	5.6	16.3	11.1	6.0	7.1	2.8	6.3	4.5	5.5	13.9	8.7	6.9	20.3	23.2	2.4	11.5	7.9	28.5	1.4	24.8	38.7	4.8	10.0	1.7	34.4	1.2	8.1	30.3	0.8	6.1	2.2	3.6	2.4	91.0	5.4	1.6	18.6	66.2	7.4	0.5	98.1	13.7	6.0	23.1	4.6	11.2	2.2	1.2	4.9	1.0	18.3	43.6	0.6	14.4	1.9	8.5	3.2	2.5	7.8	22.3	15.1	1.3	8.4	4.1	3.2	15.9	2.2	1.1	31.1	1.6	11.5	10.0	2.8	96.1	2.7	1.6	15.4	1.1	39.1	2.5	0.8	61.8	1.4	27.3	0.1	0.1	0.1	0.1	0.1	0.0	1.6	0.2	0.0	0.1	1.2	0.5	0.0	0.6	0.0	0.7	5.7	6.2	14.7	9.1	5.9	5.9	6.3	5.4	6.6	5.6	7.1	6.9	7.6	3.2	4.2	3.3	1.2	7.9	2.6	4.1	4.0	0.7	13.6	9.8	1.7	27.1	2.2	14.7	0.0	2.0	0.5	10.8	15.6	42.5	37.5	1.9	7.1	11.1	7.8	4.8	0.2	30.3	3.5	26.0	8.2	4.2	9.5	9.0	6.8	68.9	53.9	1.7	0.4	11.4	6.1	7.3	15.9	2.2	6.5	11.4	14.2	0.0	12.8	2.1	0.0	0.5	1.2	20.7	14.0	5.3	1.9	1.8	45.3	46.7	1.3	0.5	13.1	9.4	6.3	0.8	1.2	4.9	12.6	1.4	1.7	6.5	23.5	2.8
IDH1		ENSG00000138413	"Isocitrate dehydrogenase (NADP(+)) 1"	O75874	2	208236229-208266074	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Glyoxylate bypass, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 536.3"	"Cell type enhanced"	"Detected in all"		"Cytotrophoblasts: 320.2;Granulosa cells: 257.5;Hepatocytes: 328.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"Hep G2: 768.1;RT4: 524.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB033218, HPA035248, HPA057936, CAB062556"	Enhanced		Approved	"Nuclear bodies,Cytosol"		NA	NA		16000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 40: Granulosa cells - Unknown function"	"Nuclear bodies, Cytosol"		"CAB033218: AB_2123166, CAB062556: AB_2665593, HPA035248: AB_10600714, HPA057936: AB_2683559"	"unprognostic (2.79e-1)"	"unprognostic (1.00e-1)"	"unprognostic (1.02e-1)"	"unprognostic (2.47e-3)"	"unprognostic (1.93e-1)"	"unprognostic (2.39e-2)"	"prognostic unfavorable (6.93e-5)"	"unprognostic (3.32e-1)"	"unprognostic (2.20e-3)"	"unprognostic (8.03e-2)"	"unprognostic (5.54e-2)"	"unprognostic (4.18e-3)"	"prognostic unfavorable (2.45e-5)"	"unprognostic (2.09e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.13e-1)"	"unprognostic (2.69e-2)"	150.8	230.8	24.0	37.5	23.9	10.7	63.0	24.6	30.9	67.9	40.8	124.9	179.4	22.9	164.9	92.2	36.6	69.5	25.3	23.5	26.1	122.0	536.3	49.8	33.3	26.4	25.7	84.4	39.9	42.0	16.7	82.5	25.9	214.6	131.2	35.0	59.3	79.1	25.7	23.6	117.4	43.8	25.5	40.1	113.6	57.0	30.0	21.8	45.5	28.1	29.8	153.1	39.9	30.6	66.5	109.6	152.5	63.3	275.1	191.4	86.7	26.3	122.3	44.2	107.3	176.1	159.1	13.1	168.8	84.4	181.6	101.4	112.4	130.7	43.0	8.8	41.7	56.7	87.3	768.1	367.3	37.0	54.7	169.5	278.0	102.7	74.2	69.8	126.1	37.2	58.1	44.5	68.9	42.8	26.3	66.2	284.5	479.7	43.9	25.2	54.8	37.8	206.3	524.0	25.9	45.2	100.5	99.7	351.7	161.2	37.9	111.0	81.1	45.2	44.1	65.3	29.6	20.8	34.5	16.9	148.2	226.7	37.0	12.4	70.1	11.0	9.1	32.3	10.6	10.6	8.2	10.9	50.9	10.1	6.7	7.8	13.8	17.2	15.5	18.8	15.1	29.9	24.0	23.9	24.6	30.9	23.5	26.1	26.4	25.7	25.9	25.5	30.0	30.6	13.9	12.8	49.5	39.2	20.2	12.4	18.8	60.5	52.3	19.5	61.8	31.5	21.8	45.8	69.1	29.5	25.0	320.2	23.7	106.8	21.5	31.1	13.8	31.0	23.4	22.0	58.4	30.3	16.6	86.5	178.8	29.6	76.0	108.8	14.0	257.5	39.7	328.2	175.3	11.8	16.2	98.4	57.0	130.2	23.8	11.2	24.5	71.7	26.6	19.7	47.8	25.4	18.6	66.4	20.0	44.8	55.5	29.3	13.7	53.2	181.2	108.5	21.9	56.6	13.1	7.8	23.6	8.0	26.2	82.4	14.9	95.6	19.8	127.1	129.3	46.7
IDH2		ENSG00000182054	"Isocitrate dehydrogenase (NADP(+)) 2"	P48735	15	90083045-90102477	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Glyoxylate bypass, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in all"	4	"heart muscle: 492.6;skeletal muscle: 1302.3;tongue: 1611.3"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 732.5;Distal tubular cells: 1168.0;Extravillous trophoblasts: 586.7;Syncytiotrophoblasts: 573.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"MOLT-4: 425.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA007831	Enhanced		Supported	Mitochondria		NA	NA		5200000	"Cluster 51: Monocytes - Innate immune response"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 14: REH - Unknown function"	"Cluster 47: Cytotrophoblasts - Unknown function"	Mitochondria		"HPA007831: AB_1851397"	"unprognostic (2.45e-2)"	"prognostic favorable (5.15e-5)"	"unprognostic (2.92e-1)"	"unprognostic (1.53e-1)"	"unprognostic (3.53e-1)"	"unprognostic (8.46e-2)"	"unprognostic (3.83e-2)"	"unprognostic (2.55e-3)"	"unprognostic (1.86e-2)"	"unprognostic (1.89e-2)"	"unprognostic (2.76e-1)"	"unprognostic (4.90e-2)"	"unprognostic (2.19e-3)"	"unprognostic (3.92e-3)"	"unprognostic (4.46e-1)"	"unprognostic (1.30e-2)"	"unprognostic (2.58e-2)"	32.8	10.5	56.5	60.2	67.8	161.1	51.1	57.1	59.8	36.6	76.6	95.9	97.2	29.0	12.5	140.6	32.7	31.7	492.6	47.2	55.0	208.3	274.7	32.0	77.1	61.0	61.3	13.6	128.7	104.0	15.5	87.3	54.4	76.2	84.1	5.4	163.1	90.4	1302.3	61.8	84.3	79.8	52.9	36.8	175.7	5.3	71.6	148.7	16.0	1611.3	66.0	53.3	49.4	57.6	61.3	33.5	169.9	169.8	23.3	28.3	144.5	74.5	110.8	68.0	72.6	16.1	51.1	72.7	21.0	61.2	65.1	20.8	25.1	22.4	32.0	143.8	16.9	122.9	12.7	119.7	28.1	85.1	118.2	59.7	12.7	16.3	13.0	82.1	141.0	246.4	18.9	59.3	53.0	175.3	425.0	131.2	51.8	81.9	14.3	352.0	122.4	213.7	105.6	71.3	244.5	125.3	92.1	359.8	29.9	94.2	290.9	256.9	34.0	120.4	17.0	16.1	34.9	101.5	20.5	9.0	38.4	175.0	71.2	45.0	112.8	75.6	105.9	199.1	53.2	70.1	77.0	120.1	136.9	47.7	42.9	71.8	22.9	99.9	252.1	79.4	72.4	163.4	56.5	67.8	57.1	59.8	47.2	55.0	61.0	61.3	54.4	52.9	71.6	57.6	16.9	6.4	21.0	40.1	64.2	39.9	98.8	91.6	12.5	6.2	90.5	48.1	445.9	114.4	95.8	75.4	10.4	732.5	84.0	70.0	1168.0	252.8	5.6	96.4	25.7	41.6	61.7	193.8	11.8	288.8	586.7	44.7	88.2	50.9	31.6	29.2	38.2	283.1	263.7	10.1	8.3	158.3	229.9	77.7	101.1	3.2	14.0	79.0	58.7	5.6	85.3	20.9	119.4	16.6	27.3	116.6	105.0	35.3	185.9	170.3	69.6	205.0	167.9	5.4	13.1	60.8	73.4	0.6	15.6	113.3	67.1	573.0	88.1	14.7	305.1	140.1
IDH3A		ENSG00000166411	"Isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha"	P50213	15	78131498-78171945	"Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Tricarboxylic acid cycle"	Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"tongue: 99.7"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"plasmacytoid DC: 144.4"	"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041465, HPA062971"	Supported		Enhanced	Mitochondria		No	No		110000	"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Mitochondria		"HPA041465: AB_10794377, HPA062971: AB_2684913"	"unprognostic (2.33e-1)"	"unprognostic (1.21e-1)"	"unprognostic (5.76e-3)"	"unprognostic (2.26e-1)"	"unprognostic (1.02e-1)"	"unprognostic (4.01e-1)"	"unprognostic (2.29e-1)"	"unprognostic (6.47e-2)"	"unprognostic (1.69e-2)"	"unprognostic (2.30e-1)"	"unprognostic (3.05e-1)"	"unprognostic (1.42e-1)"	"prognostic favorable (6.49e-8)"	"unprognostic (1.40e-1)"	"unprognostic (3.08e-2)"	"unprognostic (4.49e-2)"	"unprognostic (3.39e-2)"	22.6	25.1	11.5	19.9	12.6	9.7	9.6	17.0	14.7	12.4	21.4	26.2	36.6	13.7	7.8	17.0	11.0	9.0	62.5	14.8	13.2	16.8	14.2	11.9	17.1	13.0	13.1	10.8	13.0	54.7	6.9	12.1	15.2	13.9	26.7	26.2	16.2	16.1	79.4	15.8	36.0	17.1	10.1	15.3	11.9	16.9	14.3	35.0	11.2	99.7	24.8	17.7	11.1	14.8	43.8	58.5	10.4	36.5	25.5	26.1	22.6	50.8	24.5	40.6	30.5	41.6	25.8	91.6	36.8	29.9	59.9	64.2	98.2	39.3	37.0	40.7	32.2	35.7	62.4	19.2	21.8	69.8	48.8	19.9	23.6	39.4	41.2	19.3	25.7	32.0	46.4	35.9	26.0	41.4	51.4	17.4	12.9	25.2	21.8	29.3	44.4	28.1	33.4	58.3	41.4	15.8	58.2	82.1	47.1	19.1	32.7	37.4	26.4	47.6	43.9	63.1	83.1	41.5	99.9	48.8	33.2	64.9	37.7	16.9	27.9	8.3	15.1	52.9	16.4	27.7	14.7	13.5	43.5	32.6	15.2	16.4	15.5	17.3	54.8	144.4	17.7	23.2	11.5	12.6	17.0	14.7	14.8	13.2	13.0	13.1	15.2	10.1	14.3	14.8	18.0	9.6	16.5	22.9	30.6	56.0	58.7	51.4	33.0	35.1	10.9	12.6	17.5	14.3	22.6	25.8	37.5	38.3	63.0	69.0	82.2	26.1	52.2	19.9	13.4	17.5	19.2	9.4	45.9	17.9	40.4	21.2	11.7	9.2	27.3	14.5	10.8	22.4	26.5	26.9	53.3	37.6	69.2	24.9	28.6	23.4	20.8	26.4	26.6	12.2	16.0	29.3	12.3	19.6	17.9	21.5	37.9	23.7	33.2	40.6	49.6	48.1	38.2	34.6	13.1	23.8	25.5	45.7	26.2	28.4	41.2	68.4	17.7	37.2	56.0	42.0
IDO1	"IDO, INDO"	ENSG00000131203	"Indoleamine 2,3-dioxygenase 1"	P14902	8	39902275-39928790	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Immunity, Tryptophan catabolism"	"Dioxygenase, Oxidoreductase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 58.7;placenta: 110.9"	"Cell type enriched"	"Detected in many"	11	"monocytes: 2612.3"	"Low cancer specificity"	"Detected in all"			"Not detected"	"Not detected"			"Immune cell enriched"	"Detected in many"	14	"eosinophil: 465.0"	"Lineage enriched"	"Detected in many"	18	"granulocytes: 465.0"	"Cell line enriched"	"Detected in some"	7	"EFO-21: 61.8"	"Region enriched"	"Detected in many"	12	"basal ganglia: 34.1"	"Low region specificity"	"Detected in all"			"HPA023072, HPA023149, HPA027772, CAB072820"	Enhanced		Supported	Nucleoplasm,Vesicles,Mitochondria,Cytosol		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 28: Placenta - Pregnancy"	"Cluster 38: EFO-21 - Unknown function"	"Cluster 3: Monocytes - Immune response regulation"	Cytosol	"Nucleoplasm, Vesicles, Mitochondria"	"CAB072820: , HPA023072: AB_1846220, HPA023149: AB_1846221, HPA027772: AB_1846222"	"unprognostic (1.68e-2)"	"unprognostic (1.71e-2)"	"unprognostic (4.08e-3)"	"unprognostic (7.21e-3)"	"unprognostic (1.90e-1)"	"unprognostic (1.09e-2)"	"unprognostic (1.86e-1)"	"unprognostic (3.06e-2)"	"prognostic favorable (5.27e-4)"	"prognostic favorable (3.32e-4)"	"unprognostic (3.59e-2)"	"unprognostic (2.74e-1)"	"prognostic unfavorable (1.12e-7)"	"unprognostic (4.18e-2)"	"unprognostic (4.42e-2)"	"unprognostic (1.16e-1)"	"unprognostic (1.97e-2)"	9.8	0.7	0.6	40.5	0.4	0.7	2.0	0.4	0.8	7.2	1.0	5.3	10.3	10.2	1.2	1.3	2.6	6.2	1.8	0.4	0.6	1.7	2.4	25.9	58.7	0.7	0.3	1.2	1.2	0.2	0.1	110.9	0.5	2.0	8.2	1.3	1.9	3.0	8.1	1.3	8.4	2.4	0.4	23.0	5.8	1.1	0.8	31.2	4.0	0.6	31.5	9.1	0.5	0.6	0.1	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.9	7.6	4.8	0.3	0.8	0.0	61.8	0.0	3.3	0.2	0.0	0.0	0.0	0.3	0.0	0.0	0.5	0.0	0.1	0.4	0.1	0.0	0.0	0.2	0.0	0.3	0.4	0.1	0.0	0.1	0.0	0.1	0.0	0.1	8.4	0.0	0.2	0.0	0.0	0.1	0.0	0.1	0.1	0.1	0.1	0.1	0.2	2.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	9.1	0.2	0.2	0.0	0.3	0.0	32.5	1.3	465.0	0.1	1.4	0.1	0.2	0.1	0.0	26.4	0.3	0.1	0.2	4.9	0.1	0.1	0.3	0.1	1.2	0.6	0.4	0.4	0.8	0.4	0.6	0.7	0.3	0.5	0.4	0.8	0.6	24.9	0.0	0.5	0.7	4.4	0.4	0.2	18.3	0.0	0.0	0.5	0.1	0.3	0.0	76.0	0.0	0.0	0.0	0.3	8.3	0.0	4.4	3.7	70.1	23.0	6.9	0.0	0.0	0.2	8.1	0.0	0.3	0.0	223.3	0.0	0.0	0.0	0.0	0.8	0.0	0.2	0.0	2.0	3.7	28.1	1.8	0.0	13.6	0.0	0.0	2612.3	3.0	0.0	0.0	0.1	0.4	0.0	0.4	2.4	0.5	0.0	0.0	33.3	0.2	0.0	1.2	8.4	0.0	0.1	0.1	0.6	0.0	1.3	0.0	1.3	2.0
IL4I1	FIG1	ENSG00000104951	"Interleukin 4 induced 1"	Q96RQ9	19	49889654-49929539	"Enzymes, Metabolic proteins, Predicted secreted proteins"	"Adaptive immunity, Immunity"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"lymphoid tissue: 18.3;testis: 26.8"	"Group enriched"	"Detected in many"	5	"Langerhans cells: 295.1;monocytes: 682.5"	"Cancer enhanced"	"Detected in all"		"ovarian cancer: 35.4"	"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in many"		"MAIT T-cell: 103.4"	"Group enriched"	"Detected in many"	6	"monocytes: 36.8;T-cells: 103.4"	"Cell line enhanced"	"Detected in many"		"EFO-21: 34.3;HDLM-2: 62.4;Karpas-707: 47.3"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA045598	Enhanced		Approved	Nucleoplasm,Cytosol	"Secreted to blood"	NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 83: Testis - Spermatogenesis"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 3: Monocytes - Immune response regulation"	"Nucleoplasm, Cytosol"		"HPA045598: AB_10969138"	"unprognostic (6.23e-2)"	"unprognostic (1.32e-2)"	"unprognostic (8.39e-2)"	"unprognostic (1.50e-1)"	"prognostic unfavorable (1.33e-4)"	"unprognostic (5.61e-2)"	"unprognostic (3.74e-3)"	"unprognostic (7.03e-2)"	"unprognostic (2.52e-2)"	"unprognostic (3.84e-3)"	"unprognostic (1.49e-1)"	"unprognostic (1.18e-1)"	"prognostic unfavorable (1.23e-10)"	"unprognostic (2.10e-1)"	"unprognostic (1.01e-1)"	"unprognostic (6.44e-2)"	"unprognostic (2.11e-3)"	1.6	0.6	0.4	18.3	0.6	4.2	0.9	0.8	0.6	1.1	0.7	1.7	4.1	1.6	0.2	0.6	3.9	2.0	0.5	0.6	0.5	4.8	1.2	2.4	9.3	1.7	0.9	0.4	0.7	0.2	0.6	1.9	1.8	0.8	1.4	0.1	0.9	0.5	0.3	1.3	2.7	1.5	1.0	4.1	3.1	26.8	1.2	3.4	0.5	0.2	6.7	4.5	0.5	2.3	1.0	1.2	0.8	0.7	0.0	0.8	0.3	0.5	2.0	1.4	2.1	0.7	1.9	3.5	34.3	0.4	2.9	0.5	0.4	0.0	0.2	62.4	0.2	1.6	0.1	0.5	0.1	1.2	12.3	1.0	0.4	0.6	0.1	0.4	2.6	0.4	0.4	47.3	0.1	0.4	0.7	2.1	0.4	0.9	0.1	1.0	0.9	3.6	2.5	3.2	0.7	0.8	0.5	0.9	0.5	0.2	0.4	2.8	2.9	7.1	1.0	0.1	1.0	4.1	9.7	2.0	1.0	0.5	0.7	0.3	22.0	0.3	6.4	36.8	103.4	0.4	13.2	11.5	11.6	0.2	0.3	0.1	0.5	1.3	5.3	1.3	0.7	8.8	0.4	0.6	0.8	0.6	0.6	0.5	1.7	0.9	1.8	1.0	1.2	2.3	0.8	0.0	0.0	0.0	3.6	9.7	0.6	9.8	0.0	0.1	1.2	1.3	0.5	0.0	5.5	3.7	0.0	0.4	1.0	0.2	0.0	3.5	75.4	2.9	0.6	6.7	0.0	0.0	0.4	4.0	0.7	1.3	0.5	2.1	1.3	0.1	1.1	0.2	97.4	0.0	0.4	0.3	6.1	3.0	295.1	18.4	0.3	38.8	3.6	1.9	682.5	0.1	1.0	0.0	0.4	0.5	0.1	0.4	0.7	1.4	0.3	2.7	1.6	0.2	0.0	0.2	2.5	45.2	3.6	0.4	8.2	0.8	6.3	0.0	0.2	2.1
IMPDH1	"LCA11, RP10, sWSS2608"	ENSG00000106348	"Inosine monophosphate dehydrogenase 1"	P20839	7	128392277-128410252	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"GMP biosynthesis, Purine biosynthesis"	"DNA-binding, Oxidoreductase, RNA-binding"	"Disease variant, FDA approved drug targets, Leber congenital amaurosis, Retinitis pigmentosa"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"retina: 106.2"	"Cell type enhanced"	"Detected in many"		"Bipolar cells: 165.8;Cone photoreceptor cells: 141.8;Horizontal cells: 121.1;Rod photoreceptor cells: 205.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"classical monocyte: 89.1;eosinophil: 89.1;intermediate monocyte: 104.5;myeloid DC: 59.9;neutrophil: 197.5;non-classical monocyte: 135.9"	"Group enriched"	"Detected in all"	5	"dendritic cells: 59.9;granulocytes: 197.5;monocytes: 135.9"	"Cell line enhanced"	"Detected in all"		"SK-BR-3: 374.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001400	Approved		Supported	"Cytosol,Rods & Rings"		NA	NA		17000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 79: Retina - Phototransduction"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 56: Bipolar cells - Visual perception"	Cytosol	"Rods & Rings"	"HPA001400: AB_1079139"	"unprognostic (2.84e-1)"	"prognostic unfavorable (3.87e-4)"	"unprognostic (2.23e-2)"	"unprognostic (6.45e-2)"	"prognostic unfavorable (7.31e-5)"	"unprognostic (6.03e-2)"	"prognostic unfavorable (1.12e-7)"	"unprognostic (1.24e-1)"	"unprognostic (7.45e-3)"	"unprognostic (1.03e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.50e-1)"	"prognostic unfavorable (1.78e-12)"	"unprognostic (1.65e-1)"	"unprognostic (1.19e-1)"	"unprognostic (1.10e-1)"	"prognostic unfavorable (3.72e-5)"	54.8	15.9	19.2	33.8	18.5	44.1	38.7	15.7	23.7	18.5	12.7	24.8	8.3	15.1	2.5	30.0	17.7	11.9	23.7	18.1	17.8	15.8	5.7	31.7	25.5	26.3	18.7	20.5	30.1	5.3	26.7	11.4	25.6	27.8	9.8	106.2	29.5	13.1	4.7	23.2	19.1	19.6	17.1	55.9	48.9	16.5	20.0	8.4	11.5	6.2	15.9	29.4	20.4	17.1	111.5	93.2	13.8	102.8	56.5	40.7	38.8	74.1	46.4	61.9	40.1	68.3	35.0	70.8	24.7	111.1	64.4	83.3	78.6	104.1	30.9	25.8	87.1	46.4	66.8	49.1	51.4	62.1	21.1	49.4	49.5	63.2	62.5	29.2	74.5	42.0	46.9	51.8	21.0	76.1	44.1	164.9	77.4	87.7	108.0	51.9	25.2	150.8	27.5	35.1	58.3	55.6	48.0	374.6	68.3	8.6	42.7	119.7	68.5	103.6	37.7	55.0	53.6	38.5	38.3	90.6	53.0	134.0	64.6	11.2	89.1	89.1	22.7	104.5	24.4	15.5	17.9	20.2	59.9	8.9	10.3	12.7	197.5	11.7	135.9	6.0	21.5	58.3	19.2	18.5	15.7	23.7	18.1	17.8	26.3	18.7	25.6	17.1	20.0	17.1	66.8	0.0	11.2	4.6	13.5	8.8	9.3	13.6	9.6	165.8	12.8	9.9	5.1	2.8	8.6	5.5	141.8	3.3	11.1	6.3	5.9	8.1	0.5	4.0	10.9	20.3	9.6	9.7	8.2	17.8	21.3	15.1	44.9	6.5	21.0	46.0	13.6	1.0	46.1	121.1	11.2	10.1	28.5	58.5	21.7	2.0	4.7	38.2	16.0	3.7	65.3	27.3	24.7	2.0	1.5	10.9	3.1	6.8	29.6	21.5	0.8	1.1	7.4	205.5	0.0	9.0	17.3	2.9	16.9	15.8	7.4	2.3	20.4	18.6	11.9	10.3
IMPDH2		ENSG00000178035	"Inosine monophosphate dehydrogenase 2"	P12268	3	49024325-49029447	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"GMP biosynthesis, Purine biosynthesis"	"DNA-binding, Oxidoreductase, RNA-binding"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"HPA001400, CAB020717"	Approved		Supported	"Cytosol,Rods & Rings"		NA	NA		340000	"Cluster 30: Non-specific - Translation"	"Cluster 50: Non-specific - Ribosome"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 10: Non-specific - Unknown function"	Cytosol	"Rods & Rings"	"CAB020717: , HPA001400: AB_1079139"	"unprognostic (2.09e-2)"	"unprognostic (2.91e-1)"	"unprognostic (5.96e-2)"	"unprognostic (1.20e-1)"	"unprognostic (7.31e-3)"	"unprognostic (1.56e-1)"	"prognostic unfavorable (3.22e-4)"	"unprognostic (1.30e-1)"	"unprognostic (2.65e-1)"	"unprognostic (2.17e-1)"	"unprognostic (5.44e-2)"	"unprognostic (4.24e-2)"	"unprognostic (1.30e-1)"	"unprognostic (3.85e-1)"	"unprognostic (5.80e-2)"	"unprognostic (2.24e-1)"	"unprognostic (4.47e-2)"	109.1	89.3	42.1	68.0	43.0	105.3	188.6	44.2	41.6	169.6	37.3	100.8	75.3	113.5	48.2	169.0	199.3	64.9	70.0	39.5	45.2	67.5	63.5	83.3	78.7	46.9	43.2	331.0	313.9	55.7	65.0	81.0	46.6	97.6	121.2	22.0	87.9	66.4	272.8	180.0	74.1	100.9	45.1	68.6	93.4	36.1	43.8	95.9	75.1	124.4	122.0	119.7	137.5	48.9	271.8	150.6	201.6	211.3	309.2	558.4	200.6	180.8	298.2	425.5	361.0	265.8	235.2	485.7	128.2	220.7	119.5	183.1	433.6	369.8	371.1	119.9	135.3	362.2	205.0	257.8	264.4	388.4	139.0	497.7	403.1	414.6	756.5	331.8	313.5	337.7	221.7	266.2	354.1	213.4	327.0	258.9	269.0	255.4	300.2	143.5	218.4	487.9	251.7	166.2	130.2	128.9	198.1	216.5	341.3	170.2	277.3	166.1	151.4	181.0	347.7	449.5	468.8	253.3	193.3	227.3	214.1	421.9	188.1	21.8	27.8	10.7	43.6	46.8	81.9	79.7	58.4	47.7	51.1	79.6	84.9	71.6	10.9	60.5	41.6	38.0	40.2	45.2	42.1	43.0	44.2	41.6	39.5	45.2	46.9	43.2	46.6	45.1	43.8	48.9	40.5	64.1	60.9	3.9	92.2	202.7	255.0	253.8	229.9	16.1	202.7	231.8	32.3	74.4	122.4	36.8	14.6	327.3	34.5	51.1	80.3	133.6	2.7	49.0	120.5	60.9	60.7	112.5	2.9	187.1	280.6	104.4	70.3	51.2	66.1	98.0	52.8	24.9	95.3	15.2	4.1	124.4	114.0	55.9	105.4	6.7	123.3	50.0	88.9	1.0	67.3	26.5	24.7	4.0	5.2	108.8	70.8	71.1	64.6	160.1	47.4	92.0	53.7	15.8	39.5	149.4	215.1	22.6	62.5	195.7	195.6	314.0	52.3	166.8	266.5	157.2
IVD	ACAD2	ENSG00000128928	"Isovaleryl-CoA dehydrogenase"	P26440	15	40405485-40435947	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Hepatocytes: 135.0;Theca cells: 105.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041391, HPA044250"	Enhanced		Supported	Nucleoplasm,Mitochondria		NA	NA			"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 35: Non-specific - Unknown function"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 52: Non-specific - Transcription"	Mitochondria	Nucleoplasm	"HPA041391: AB_2677449, HPA044250: AB_2678875"	"unprognostic (9.30e-2)"	"unprognostic (3.31e-1)"	"unprognostic (1.36e-2)"	"unprognostic (4.24e-2)"	"unprognostic (7.53e-2)"	"unprognostic (1.74e-1)"	"prognostic favorable (1.95e-5)"	"unprognostic (1.50e-2)"	"unprognostic (2.53e-1)"	"unprognostic (2.84e-2)"	"unprognostic (4.08e-2)"	"unprognostic (2.31e-1)"	"prognostic favorable (2.91e-9)"	"unprognostic (1.40e-1)"	"unprognostic (3.40e-2)"	"unprognostic (1.14e-1)"	"unprognostic (5.46e-3)"	25.8	80.5	35.1	14.5	40.8	15.9	45.3	35.6	40.8	29.4	39.5	31.6	24.3	26.4	29.0	16.0	35.0	21.5	61.7	34.0	41.5	59.1	145.4	24.3	19.6	40.2	38.8	43.3	27.4	39.2	58.3	15.3	37.5	42.1	27.2	13.0	31.8	36.8	55.7	8.6	26.8	23.8	37.9	27.9	46.7	25.0	44.5	16.8	119.2	55.4	19.5	31.1	20.8	45.3	20.9	11.9	22.9	38.9	35.9	32.9	1.0	27.6	32.7	39.4	24.0	36.5	16.0	0.8	57.7	43.4	32.6	20.8	45.9	46.6	30.1	36.4	34.0	52.1	36.2	38.9	64.6	22.0	48.5	45.3	18.5	23.5	55.3	46.3	38.8	60.4	2.5	2.4	42.1	27.1	27.3	38.9	17.8	1.3	33.0	41.2	32.6	27.9	45.2	51.6	37.3	21.5	38.2	83.4	18.7	21.5	69.0	117.6	27.6	29.9	20.2	23.6	24.9	54.5	38.5	1.0	30.9	22.8	28.4	17.0	24.8	36.7	33.3	36.1	31.0	27.5	18.5	26.6	58.8	27.6	18.5	26.7	2.3	39.4	73.1	89.2	26.9	24.3	35.1	40.8	35.6	40.8	34.0	41.5	40.2	38.8	37.5	37.9	44.5	45.3	13.1	28.9	54.5	27.4	19.0	2.3	21.0	17.3	13.1	26.0	27.5	22.2	88.0	45.8	29.9	44.1	14.6	20.3	34.0	17.9	95.9	19.7	5.4	21.4	31.0	18.6	19.7	21.3	15.3	14.9	7.3	20.2	29.6	19.9	34.7	46.5	21.4	135.0	28.1	16.8	16.6	24.4	14.2	18.3	6.2	7.4	20.5	18.6	5.4	21.5	28.8	26.0	26.8	25.1	21.4	14.8	9.4	24.8	10.0	16.6	22.0	97.3	29.3	19.9	19.7	25.0	18.2	16.1	3.7	17.4	0.6	9.9	18.0	105.7	35.4	11.9
IYD	"C6orf71, DEHAL1, dJ422F24.1"	ENSG00000009765	"Iodotyrosine deiodinase"	Q6PHW0	6	150368892-150405969	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins"		Oxidoreductase	"Congenital hypothyroidism, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	14	"thyroid gland: 472.7"	"Cell type enhanced"	"Detected in some"		"Distal enterocytes: 23.7;Hepatocytes: 25.1;Intestinal goblet cells: 21.8;Paneth cells: 22.5;Proximal enterocytes: 89.1;Proximal tubular cells: 35.4"	"Cancer enriched"	"Detected in many"	20	"thyroid cancer: 80.7"	"Not detected"	"Not detected"			"Immune cell enhanced"	"Detected in some"		"neutrophil: 1.9"	"Low lineage specificity"	"Detected in single"			"Group enriched"	"Detected in some"	7	"CACO-2: 1.3;OE19: 3.0;SK-BR-3: 3.2"	"Group enriched"	"Detected in some"	13	"hippocampal formation: 7.4;thalamus: 2.4"	"Low region specificity"	"Detected in all"			HPA059627	Enhanced		Supported	"Plasma membrane"		NA	NA			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 1: Thyroid gland - Transcription"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 45: Enterocytes - Digestion"	"Plasma membrane"		"HPA059627: AB_2684086"	"unprognostic (3.73e-4)"	"unprognostic (2.93e-2)"	"unprognostic (5.97e-2)"	"unprognostic (1.95e-2)"	"unprognostic (1.55e-1)"	"unprognostic (2.98e-2)"	"prognostic favorable (6.22e-4)"	"unprognostic (1.11e-1)"	"unprognostic (3.80e-2)"	"unprognostic (1.17e-1)"	"unprognostic (7.41e-2)"	"unprognostic (1.02e-1)"	"unprognostic (3.07e-9)"	"unprognostic (9.79e-3)"	"unprognostic (2.04e-1)"	"unprognostic (2.03e-2)"	"unprognostic (2.18e-2)"	0.1	0.0	0.4	0.6	0.3	0.3	0.5	0.6	0.6	0.1	0.2	6.4	18.1	0.2	0.6	0.0	0.0	8.9	0.5	0.3	0.1	26.6	33.6	0.7	0.5	0.5	0.4	0.0	0.4	0.0	0.0	0.0	0.6	0.2	6.5	0.2	0.1	0.0	0.0	0.2	19.6	0.2	0.0	0.1	2.0	0.2	0.5	0.0	472.7	0.0	0.2	0.1	0.0	0.5	0.0	0.0	0.0	0.1	0.0	0.3	0.1	0.0	0.0	0.0	0.0	1.3	0.2	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.1	0.0	0.1	0.2	0.1	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.0	0.0	0.1	0.1	3.0	0.1	0.0	0.1	0.1	0.0	0.2	0.1	0.0	0.0	3.2	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.1	0.1	0.0	1.6	0.5	0.3	0.2	0.4	0.2	0.2	0.1	0.1	0.0	0.4	0.2	0.2	1.9	0.7	0.2	0.3	0.2	1.3	0.4	0.3	0.6	0.6	0.3	0.1	0.5	0.4	0.6	0.0	0.5	0.5	0.7	3.2	7.8	0.0	0.0	0.1	0.6	0.2	0.0	0.1	0.3	0.4	0.8	14.3	8.9	0.0	0.0	0.1	0.0	23.7	1.9	0.3	0.0	0.9	0.3	0.4	3.6	2.7	0.1	0.2	0.0	0.7	0.0	2.2	1.3	0.1	1.1	25.1	0.1	0.0	0.1	21.8	0.0	0.0	1.2	0.1	0.0	0.7	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.4	22.5	0.0	0.0	1.0	89.1	35.4	3.6	1.3	0.0	1.7	0.3	0.1	0.1	0.0	0.4	0.3	0.9	0.4	11.5	0.7
JMJD7		ENSG00000243789	"Jumonji domain containing 7"	P0C870	15	41828092-41837581	"Enzymes, Predicted intracellular proteins"		"Aminopeptidase, Hydrolase, Monooxygenase, Oxidoreductase, Protease"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"Alveolar cells type 1: 3.2;Alveolar cells type 2: 5.2;Basal squamous epithelial cells: 1.8;Gastric mucus-secreting cells: 2.0;Squamous epithelial cells: 3.4"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"OE19: 31.2;RT4: 43.5"	"Low region specificity"	"Detected in all"							HPA005726	Approved		Approved	Cytosol		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 15: RT4 - Unknown function"	"Cluster 11: Alveolar cells - Smell perception"	Cytosol		"HPA005726: AB_1852017"	"unprognostic (2.92e-1)"	"unprognostic (7.99e-2)"	"unprognostic (1.47e-2)"	"unprognostic (2.30e-2)"	"unprognostic (9.46e-2)"	"unprognostic (1.03e-1)"	"unprognostic (1.59e-1)"	"unprognostic (1.78e-2)"	"unprognostic (2.11e-2)"	"unprognostic (1.77e-1)"	"unprognostic (2.42e-1)"	"unprognostic (8.74e-3)"	"unprognostic (3.13e-1)"	"unprognostic (7.25e-2)"	"unprognostic (1.06e-1)"	"unprognostic (3.30e-1)"	"unprognostic (1.45e-2)"	6.7	8.4	6.3	4.2	6.2	8.2	9.0	19.9	9.5	13.6	8.0	7.3	4.8	6.5	3.1	35.4	8.6	6.5	11.2	5.8	6.3	10.1	10.3	10.8	7.3	5.8	5.2	11.6	15.9	9.0	9.8	3.0	7.0	14.5	3.0	1.9	21.9	6.8	7.7	33.3	8.0	2.9	5.1	7.9	11.5	6.7	5.9	5.6	15.6	6.6	6.6	11.4	21.0	7.0	7.9	7.5	9.3	2.6	2.5	1.7	5.8	3.1	6.6	5.1	4.1	10.5	5.9	1.0	6.4	2.0	5.3	19.6	4.3	15.6	1.6	7.7	4.6	10.5	10.4	6.5	4.1	5.1	11.0	1.1	13.6	3.4	7.2	4.7	5.8	9.9	7.0	6.2	3.7	10.8	6.6	4.9	4.0	31.2	4.8	2.9	6.3	7.6	11.5	43.5	9.9	3.5	2.6	13.5	4.3	2.7	26.2	5.4	5.4	3.7	8.3	8.0	6.1	10.2	3.7	3.2	4.9	12.4	5.7	6.1	14.8	10.8	14.1	15.8	14.8	7.2	15.7	18.6	10.6	11.1	19.7	15.6	3.9	13.0	15.8	6.7	16.7	12.6	6.3	6.2	19.9	9.5	5.8	6.3	5.8	5.2	7.0	5.1	5.9	7.0	0.1	3.2	5.2	0.0	0.4	0.0	0.0	0.0	1.8	0.0	0.2	0.0	0.0	0.0	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.1	0.1	0.0	0.8	0.0	0.2	0.0	0.2	2.0	0.1	1.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.2	0.0	0.1	3.4	0.1	0.0	0.6	0.0	0.0	0.0
KDM1A	"AOF2, BHC110, KDM1, KIAA0601, LSD1"	ENSG00000004487	"Lysine demethylase 1A"	O60341	1	23019443-23083689	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Developmental protein, Oxidoreductase, Repressor"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Spermatocytes: 131.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB005884, HPA053660"	Supported		Supported	Nucleoplasm,Cytosol	"Intracellular and membrane"	NA	NA		7700	"Cluster 37: B-cells - Transcription"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 14: REH - Unknown function"	"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis"	Nucleoplasm	Cytosol	"CAB005884: AB_443964, HPA053660: AB_2682220"	"unprognostic (1.03e-1)"	"unprognostic (1.17e-1)"	"prognostic favorable (6.31e-4)"	"unprognostic (1.50e-1)"	"unprognostic (6.83e-2)"	"unprognostic (3.95e-2)"	"prognostic unfavorable (4.47e-12)"	"unprognostic (1.80e-2)"	"unprognostic (1.99e-2)"	"unprognostic (9.41e-2)"	"unprognostic (3.34e-3)"	"unprognostic (2.13e-1)"	"unprognostic (2.61e-1)"	"unprognostic (1.41e-1)"	"unprognostic (3.73e-2)"	"unprognostic (7.74e-2)"	"unprognostic (1.39e-1)"	25.7	30.8	24.7	23.5	25.8	48.1	30.6	26.5	27.0	33.1	20.4	31.6	26.4	36.0	46.9	35.0	34.2	25.3	26.1	25.3	28.2	24.7	22.3	24.5	34.7	19.8	22.0	41.4	36.2	51.2	41.5	31.5	21.0	32.2	33.8	30.9	36.6	29.4	47.3	38.2	29.2	30.1	21.2	25.2	29.3	86.9	27.4	55.8	28.5	34.0	37.2	34.6	31.5	21.8	128.1	64.7	180.8	160.7	47.0	59.5	128.4	53.1	66.4	106.0	93.7	61.2	120.5	94.5	74.1	87.6	53.7	139.5	169.5	101.0	133.3	86.3	102.7	133.0	105.7	150.6	59.6	103.7	56.0	55.6	71.4	112.8	78.9	93.0	134.1	171.7	148.0	43.4	76.3	75.9	227.3	79.2	118.3	70.8	93.0	214.7	119.1	64.1	89.0	81.0	225.0	169.9	239.4	62.4	80.2	126.1	62.7	76.2	109.5	47.0	78.4	88.1	73.6	55.6	47.1	109.3	49.2	120.4	68.3	2.0	2.5	4.3	4.1	4.3	3.4	7.4	3.5	3.8	3.1	2.1	4.5	4.9	0.2	3.0	5.5	6.8	4.4	1.4	24.7	25.8	26.5	27.0	25.3	28.2	19.8	22.0	21.0	21.2	27.4	21.8	18.7	19.2	29.1	33.6	15.9	18.6	27.1	19.9	33.0	27.5	20.4	22.1	24.4	11.5	19.0	23.9	27.1	31.6	18.1	15.7	17.6	35.4	43.5	45.9	49.3	20.4	22.8	29.7	51.1	24.7	57.2	24.8	23.4	44.4	12.0	49.5	16.8	17.2	15.0	15.2	51.2	24.9	22.4	15.1	19.7	20.3	21.5	20.2	12.4	30.0	28.1	19.3	12.3	50.3	30.4	28.1	13.5	23.0	28.9	26.3	17.2	15.7	29.5	19.8	0.0	22.2	25.0	131.8	67.1	36.1	12.8	16.6	15.4	34.3	27.6	20.5
KDM1B	"AOF1, bA204B7.3, C6orf193, dJ298J15.2, FLJ33898, FLJ34109, FLJ43328, LSD2"	ENSG00000165097	"Lysine demethylase 1B"	Q8NB78	6	18155329-18223854	"Enzymes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Developmental protein, Oxidoreductase, Repressor"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Group enriched"	"Detected in many"	5	"dendritic cells: 3.7;granulocytes: 7.2;monocytes: 8.6"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA031269, HPA055597"	Uncertain		Supported	Nucleoplasm		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 21: OE19 - Mitochondria"	"Cluster 19: Monocytes & Neutrophils - Innate immune response"	Nucleoplasm		"HPA031269: AB_10601587, HPA055597: "	"unprognostic (1.93e-1)"	"unprognostic (7.53e-2)"	"prognostic favorable (6.94e-4)"	"unprognostic (2.57e-2)"	"unprognostic (7.25e-2)"	"unprognostic (1.08e-1)"	"unprognostic (5.57e-3)"	"unprognostic (1.32e-2)"	"unprognostic (8.41e-2)"	"unprognostic (6.84e-2)"	"unprognostic (2.16e-1)"	"unprognostic (3.17e-2)"	"unprognostic (6.68e-2)"	"unprognostic (3.02e-2)"	"unprognostic (2.90e-1)"	"unprognostic (7.36e-2)"	"unprognostic (3.53e-1)"	5.9	7.6	5.6	11.4	7.6	27.2	6.3	5.3	7.8	7.6	7.6	14.1	8.0	5.7	3.7	9.1	13.4	6.0	6.8	6.6	5.9	7.8	7.4	8.8	10.4	6.9	6.7	6.7	5.9	3.2	5.8	4.6	6.1	5.2	12.2	12.0	5.7	4.7	17.3	11.2	8.9	6.9	6.2	10.5	5.6	15.7	5.6	10.8	27.2	9.1	9.4	7.7	8.1	9.4	15.1	9.7	11.2	23.0	13.8	20.5	24.5	11.7	12.6	7.5	10.2	16.3	7.4	34.1	31.6	19.2	22.8	15.5	17.8	20.8	16.0	31.6	14.6	17.2	8.6	15.0	6.7	25.5	17.5	10.3	23.4	21.5	17.7	12.1	7.7	15.9	38.3	5.2	12.7	12.6	14.1	10.5	3.8	31.6	12.8	26.8	20.3	24.4	10.7	19.8	34.2	10.6	9.7	23.5	22.9	11.7	22.3	20.3	6.5	16.9	9.5	11.9	15.5	5.2	15.9	20.0	6.4	18.9	37.8	1.2	4.6	7.2	0.5	8.6	0.3	1.2	0.5	0.5	3.7	1.3	0.5	0.2	4.9	0.3	6.9	1.6	0.7	1.3	5.6	7.6	5.3	7.8	6.6	5.9	6.9	6.7	6.1	6.2	5.6	9.4	4.9	0.0	8.2	14.7	8.7	12.7	5.7	3.8	7.4	5.0	7.6	6.6	10.4	11.5	10.4	1.8	10.4	2.7	3.0	23.0	1.9	6.6	0.7	36.2	10.0	4.2	6.7	3.8	19.0	4.3	5.1	5.8	8.2	15.5	2.5	3.3	4.2	7.7	7.5	5.0	10.8	9.6	10.2	36.7	11.7	0.7	3.7	20.6	7.2	22.5	27.7	6.6	8.2	16.1	23.8	7.2	21.2	6.8	3.7	5.4	6.2	11.2	21.0	15.5	0.0	6.9	6.2	0.7	18.2	9.7	15.9	1.4	5.6	3.1	10.6	6.6
KDM2A	"CXXC8, DKFZP434M1735, FBL11, FBL7, FBXL11, FLJ00115, JHDM1A, KIAA1004, LILINA"	ENSG00000173120	"Lysine demethylase 2A"	Q9Y2K7	11	67119263-67258082	"Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Biological rhythms, Transcription, Transcription regulation, Ubl conjugation pathway"	"Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB012272, HPA044251"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 6: T47d - Mammary gland"	"Cluster 44: Endometrium - Transcription"	Nucleoplasm		"CAB012272: , HPA044251: "	"unprognostic (7.43e-2)"	"unprognostic (1.84e-1)"	"unprognostic (4.09e-1)"	"unprognostic (8.66e-2)"	"unprognostic (1.67e-1)"	"unprognostic (2.30e-2)"	"unprognostic (6.05e-2)"	"unprognostic (2.84e-1)"	"unprognostic (4.46e-1)"	"unprognostic (2.04e-3)"	"unprognostic (3.27e-2)"	"unprognostic (5.08e-2)"	"unprognostic (2.67e-2)"	"unprognostic (3.30e-1)"	"unprognostic (1.05e-1)"	"unprognostic (5.61e-2)"	"unprognostic (9.45e-3)"	19.5	13.2	10.7	27.2	10.6	47.1	19.7	18.0	12.1	24.3	14.1	23.3	14.7	29.1	17.4	31.9	19.3	19.0	17.4	10.6	11.2	14.3	19.9	24.0	27.5	12.6	10.7	24.5	13.0	16.1	13.1	18.0	10.9	21.6	17.1	18.5	21.3	19.2	33.8	29.4	23.9	24.0	9.7	27.0	18.9	29.0	11.9	27.8	19.0	24.5	28.7	23.9	25.9	10.9	49.9	31.8	17.6	27.7	17.1	27.0	13.5	21.5	26.6	41.0	27.9	48.7	25.4	38.8	37.5	33.3	23.8	48.2	31.3	22.5	33.1	66.4	13.4	28.9	39.2	11.7	16.9	24.5	38.1	21.7	23.9	39.4	25.7	20.7	29.9	22.7	27.4	54.4	18.6	35.4	32.5	18.1	36.1	29.8	25.6	39.9	29.4	21.4	14.7	33.7	24.2	18.9	71.0	38.6	39.0	21.6	59.9	23.9	38.7	25.0	16.7	34.5	18.8	29.3	35.4	25.4	22.0	17.2	17.8	0.4	1.1	0.3	2.5	0.8	2.7	3.6	1.9	2.3	0.6	3.6	1.9	1.9	2.7	2.7	0.5	0.9	2.6	1.9	10.7	10.6	18.0	12.1	10.6	11.2	12.6	10.7	10.9	9.7	11.9	10.9	41.4	38.5	35.8	75.1	56.6	41.2	23.3	23.4	75.7	75.3	40.3	30.9	31.1	34.3	31.0	16.5	137.6	23.9	77.5	43.2	0.0	17.3	20.6	84.8	63.0	38.4	31.8	22.1	89.4	14.5	13.4	32.4	42.8	112.3	27.3	42.1	29.3	35.5	21.5	95.9	89.8	27.5	24.4	46.5	59.6	11.2	21.5	49.1	19.6	104.0	43.3	19.8	33.0	96.0	99.5	25.9	25.5	23.0	72.5	37.2	21.2	10.3	40.0	111.7	19.7	40.2	32.3	52.0	38.1	78.7	47.7	32.3	66.9	33.8	29.5	48.7
KDM2B	"CXXC2, Fbl10, FBXL10, JHDM1B, PCCX2"	ENSG00000089094	"Lysine demethylase 2B"	Q8NHM5	12	121429096-121581023	"Enzymes, Predicted intracellular proteins"	"Transcription, Transcription regulation, Ubl conjugation pathway"	"Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor, RNA-binding, rRNA-binding"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA071257			Supported	Nucleoplasm		NA	NA			"Cluster 19: B-cells - Humoral immune response"	"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 5: NTERA-2 - Transcription"	"Cluster 29: Early spermatids - Spermatogenesis"	Nucleoplasm		"HPA071257: "	"unprognostic (7.67e-2)"	"unprognostic (3.72e-3)"	"unprognostic (2.15e-1)"	"unprognostic (1.69e-1)"	"unprognostic (1.37e-1)"	"prognostic favorable (6.74e-6)"	"unprognostic (1.16e-1)"	"unprognostic (5.45e-2)"	"unprognostic (1.01e-2)"	"unprognostic (1.95e-1)"	"prognostic favorable (8.64e-4)"	"unprognostic (1.77e-1)"	"unprognostic (4.44e-3)"	"unprognostic (1.44e-2)"	"unprognostic (3.90e-2)"	"unprognostic (7.07e-2)"	"unprognostic (4.82e-2)"	9.7	8.4	7.1	18.9	8.7	16.9	10.0	12.9	10.7	15.6	7.4	12.2	8.2	11.5	5.5	20.2	12.4	7.0	8.7	7.3	5.6	11.1	15.6	13.1	22.9	8.3	6.3	15.2	11.6	10.8	9.4	7.3	9.2	9.5	7.6	9.7	12.6	6.1	15.2	28.0	18.9	8.3	5.4	21.4	10.9	14.0	7.8	23.1	11.2	6.1	21.6	12.3	16.9	9.0	15.2	19.1	31.3	9.8	8.7	7.6	34.8	12.4	19.1	17.8	14.9	24.0	7.7	69.3	20.6	11.2	9.9	13.1	34.3	13.7	14.4	29.3	24.0	38.0	15.9	19.4	10.3	44.0	29.5	6.9	7.4	16.9	12.3	19.1	12.7	33.6	31.4	8.8	8.5	20.4	54.5	51.8	55.8	11.0	15.1	61.0	16.4	34.1	9.8	24.5	37.1	21.4	23.8	14.0	14.4	29.5	25.0	49.2	17.3	19.0	15.4	19.2	13.9	23.9	21.3	64.5	17.6	35.2	12.3	4.5	2.8	2.4	6.3	2.3	4.9	9.5	4.9	3.5	3.9	9.3	4.3	5.8	0.4	2.0	1.7	3.5	4.6	3.4	7.1	8.7	12.9	10.7	7.3	5.6	8.3	6.3	9.2	5.4	7.8	9.0	6.8	0.0	10.6	28.1	36.8	17.0	7.1	4.0	13.6	20.1	10.3	6.7	14.6	14.3	5.4	11.0	12.5	6.7	43.3	3.8	11.7	7.5	57.0	13.0	7.0	8.8	5.4	22.5	36.2	5.8	11.2	8.3	9.2	12.0	14.0	16.5	9.7	15.4	24.4	15.2	41.6	6.1	6.1	21.1	61.0	60.1	7.8	25.5	16.0	26.2	48.0	4.1	24.7	31.2	44.1	5.8	4.7	7.2	34.1	11.2	6.5	4.2	5.7	16.1	19.7	6.5	8.1	11.4	18.3	13.9	15.2	6.6	24.8	6.2	7.4	6.3
KDM3A	"JHMD2A, JMJD1, JMJD1A, KIAA0742, TSGA"	ENSG00000115548	"Lysine demethylase 3A"	Q9Y4C1	2	86440647-86492716	"Enzymes, Predicted intracellular proteins"	"Differentiation, Spermatogenesis, Transcription, Transcription regulation"	"Activator, Chromatin regulator, Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA055543, HPA065162"			Enhanced	Nucleoplasm		NA	NA			"Cluster 34: Basophils - Unknown function"	"Cluster 34: Non-specific - Transcription"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 25: Spermatids - Spermatogenesis"	Nucleoplasm		"HPA055543: AB_2682842, HPA065162: AB_2685424"	"unprognostic (1.97e-2)"	"unprognostic (3.03e-3)"	"unprognostic (1.32e-2)"	"unprognostic (4.04e-2)"	"unprognostic (5.06e-2)"	"unprognostic (5.24e-2)"	"prognostic unfavorable (2.15e-6)"	"unprognostic (2.01e-1)"	"unprognostic (3.35e-3)"	"unprognostic (9.50e-3)"	"unprognostic (4.44e-2)"	"unprognostic (5.64e-2)"	"prognostic unfavorable (5.25e-4)"	"unprognostic (2.17e-1)"	"unprognostic (2.24e-1)"	"unprognostic (1.24e-1)"	"unprognostic (2.66e-2)"	21.2	12.9	17.9	13.1	19.0	70.3	19.9	17.5	18.9	18.0	18.6	25.0	18.9	20.7	18.2	20.8	18.4	15.9	21.7	15.3	18.1	15.4	12.9	16.7	17.9	18.1	17.4	21.5	16.1	14.6	12.8	22.1	17.8	16.6	15.9	54.7	19.8	19.7	21.5	38.6	20.1	15.0	16.6	18.4	14.9	50.9	18.7	27.4	20.0	21.4	19.6	20.8	20.2	20.1	34.7	13.5	31.5	8.3	15.9	16.1	29.4	16.5	16.2	15.1	18.5	17.3	14.3	20.1	30.4	13.8	31.1	21.5	23.7	16.6	29.2	27.1	19.7	32.4	12.6	24.8	11.9	26.1	19.9	17.8	24.5	13.6	24.9	51.9	19.0	18.5	21.1	31.9	16.1	8.9	36.2	36.4	28.3	20.6	20.4	24.5	42.6	44.0	13.6	19.2	24.4	25.9	21.7	15.5	30.2	27.5	9.0	16.8	21.2	30.6	12.6	31.8	19.1	33.3	33.9	29.6	38.8	26.6	38.2	16.9	3.0	5.8	6.7	3.3	7.1	4.2	7.5	6.6	4.6	3.6	7.9	7.0	13.4	5.0	2.2	4.2	8.3	3.9	17.9	19.0	17.5	18.9	15.3	18.1	18.1	17.4	17.8	16.6	18.7	20.1	26.0	35.3	17.0	56.8	19.7	30.5	23.2	19.5	43.3	24.0	18.9	14.6	30.3	7.2	24.8	5.5	52.1	5.2	29.2	24.2	0.0	12.1	82.0	36.6	15.6	23.4	15.6	21.0	28.7	9.8	8.5	19.1	23.0	35.5	38.6	11.9	15.4	7.6	10.4	55.5	27.4	13.7	26.4	10.9	18.2	29.7	17.4	17.5	21.4	28.1	8.6	36.0	21.6	26.2	23.5	11.3	8.0	17.3	21.4	16.0	23.0	5.6	44.1	34.4	6.6	21.3	20.4	38.7	14.1	35.5	40.1	11.6	27.4	15.2	10.7	13.6
KDM3B	"C5orf7, JMJD1B, KIAA1082, NET22"	ENSG00000120733	"Lysine demethylase 3B"	Q7LBC6	5	138352685-138437028	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Dioxygenase, Oxidoreductase"	"Disease variant, Dwarfism, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA016610, HPA057202"	Supported		Enhanced	Nucleoplasm	"Intracellular and membrane"	NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 52: Non-specific - Ribosome"	"Cluster 12: NES - Nervous system development"	"Cluster 65: Plasmacytoid DCs - Unknown function"	Nucleoplasm		"HPA016610: AB_1852004, HPA057202: AB_2683367"	"unprognostic (1.21e-1)"	"unprognostic (1.42e-1)"	"unprognostic (1.63e-3)"	"unprognostic (1.34e-1)"	"unprognostic (6.72e-2)"	"unprognostic (1.72e-1)"	"unprognostic (5.21e-2)"	"unprognostic (1.68e-1)"	"unprognostic (2.64e-1)"	"unprognostic (4.68e-2)"	"unprognostic (1.11e-1)"	"unprognostic (4.48e-2)"	"prognostic favorable (6.67e-4)"	"unprognostic (1.73e-1)"	"unprognostic (3.05e-1)"	"unprognostic (1.43e-1)"	"unprognostic (7.60e-2)"	21.7	19.4	22.6	16.9	23.0	25.4	25.3	22.2	22.8	22.7	21.1	23.9	18.6	23.0	28.3	21.2	24.2	14.2	20.0	21.3	20.7	21.4	14.5	19.3	23.0	23.4	22.7	30.8	20.3	34.2	16.5	20.5	21.5	21.8	24.0	36.3	22.2	25.9	41.5	28.1	23.4	20.8	21.9	26.0	21.6	19.4	23.9	35.9	23.2	27.1	29.4	24.8	19.9	21.8	24.3	32.4	65.0	58.7	27.2	23.3	47.0	15.6	27.1	30.0	33.5	35.7	27.2	46.3	27.9	30.3	41.0	24.3	53.2	37.8	32.6	30.3	29.3	39.2	28.6	27.1	25.4	32.2	43.3	26.9	39.0	22.1	26.7	23.2	34.6	29.3	31.8	26.1	34.3	30.3	46.4	41.0	31.0	34.1	13.7	53.1	48.5	30.9	40.4	31.6	32.7	35.9	27.0	28.0	25.7	93.2	27.3	43.5	31.9	17.9	17.4	19.3	28.8	32.8	16.7	40.2	12.5	45.6	25.6	0.2	2.9	4.2	2.3	2.2	3.2	2.3	2.7	3.0	2.5	2.0	2.5	2.3	5.5	4.2	2.3	3.0	1.7	1.3	22.6	23.0	22.2	22.8	21.3	20.7	23.4	22.7	21.5	21.9	23.9	21.8	22.8	16.0	15.7	43.1	22.1	15.9	13.7	15.1	20.5	21.3	29.1	29.5	33.2	17.2	17.0	22.0	29.2	13.4	24.0	26.8	0.0	16.0	6.1	22.8	19.9	18.9	21.0	25.4	40.9	16.8	10.7	18.5	17.9	24.2	13.3	26.3	18.2	23.0	17.6	23.5	39.1	26.4	18.3	39.2	18.3	2.8	21.1	27.9	16.0	50.6	27.0	17.3	16.5	41.7	56.9	19.9	28.0	23.0	16.2	21.2	20.9	16.1	25.6	31.9	26.3	21.8	18.7	13.0	15.5	26.2	21.6	10.9	19.1	17.1	24.6	21.0
KDM4A	"JHDM3A, JMJD2, JMJD2A, KIAA0677, TDRD14A"	ENSG00000066135	"Lysine demethylase 4A"	O75164	1	43650149-43705518	"Enzymes, Predicted intracellular proteins"	"Host-virus interaction, Transcription, Transcription regulation"	"Chromatin regulator, Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA007610	Uncertain		Supported	"Nucleoplasm,Nucleoli fibrillar center,Cytosol"		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 56: Intestine - Transmembrane transport"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 59: Non-specific - Transcription"	"Nucleoli fibrillar center"	"Nucleoplasm, Cytosol"	"HPA007610: AB_1852006"	"unprognostic (7.01e-2)"	"unprognostic (1.50e-1)"	"unprognostic (3.22e-2)"	"unprognostic (6.18e-2)"	"unprognostic (3.54e-2)"	"unprognostic (5.40e-3)"	"prognostic unfavorable (1.39e-5)"	"unprognostic (4.88e-3)"	"unprognostic (1.13e-1)"	"unprognostic (5.47e-1)"	"unprognostic (2.70e-1)"	"unprognostic (7.95e-2)"	"unprognostic (2.81e-1)"	"unprognostic (2.32e-3)"	"unprognostic (2.02e-1)"	"unprognostic (1.92e-1)"	"unprognostic (1.28e-1)"	10.6	20.6	10.7	12.2	11.3	12.1	12.8	12.7	12.4	15.1	11.8	18.0	28.0	14.2	13.0	14.4	18.0	11.8	10.0	10.7	9.3	12.7	14.8	14.7	15.6	10.7	10.4	19.7	12.7	19.1	10.9	11.2	10.9	13.7	18.5	19.6	13.3	11.4	11.1	21.8	22.6	14.9	10.0	13.9	14.4	5.7	10.7	21.6	17.3	15.7	18.0	13.7	11.8	11.2	25.1	22.6	36.6	63.6	34.5	32.6	25.3	23.4	26.4	34.7	34.6	26.0	21.7	32.5	23.5	23.4	26.3	25.3	45.1	27.6	35.4	23.2	37.8	46.5	33.7	21.2	32.7	33.4	35.9	35.4	43.2	33.7	42.3	26.6	37.0	27.9	23.5	45.1	25.5	19.6	26.4	28.2	59.9	21.5	23.0	35.0	42.2	23.9	24.3	48.8	32.1	29.1	50.5	34.2	63.3	52.8	20.0	111.5	28.1	20.6	32.8	18.7	31.9	20.7	26.7	29.2	21.3	27.8	39.3	10.2	4.9	9.0	4.4	3.7	4.9	4.3	4.3	3.6	4.1	3.1	2.9	2.6	3.0	4.1	5.2	3.6	4.9	3.5	10.7	11.3	12.7	12.4	10.7	9.3	10.7	10.4	10.9	10.0	10.7	11.2	5.3	9.6	22.3	12.7	14.0	9.2	5.3	8.3	25.6	20.1	8.9	7.5	7.4	8.6	8.2	1.8	37.5	8.5	10.4	19.3	5.9	8.6	9.7	11.2	9.8	9.2	12.0	16.4	21.3	6.7	6.1	9.8	23.4	6.9	13.3	12.0	7.9	13.1	8.9	32.0	17.8	16.6	10.2	9.7	5.5	6.1	12.5	7.9	1.8	5.6	11.6	10.9	13.4	17.6	23.8	10.7	13.5	14.7	14.3	5.4	17.3	6.9	25.4	23.5	6.6	11.1	7.7	0.6	2.9	21.0	4.7	8.1	9.5	13.6	15.4	6.0
KDM4B	"JMJD2B, KIAA0876, TDRD14B"	ENSG00000127663	"Lysine demethylase 4B"	O94953	19	4969113-5153598	"Enzymes, Plasma proteins, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cone photoreceptor cells: 98.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Group enriched"	"Detected in many"	5	"B-cells: 5.1;dendritic cells: 1.7;granulocytes: 4.7"	"Cell line enhanced"	"Detected in all"		"T-47d: 61.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA071568			Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 72: Non-specific - Transcription"	"Cluster 6: T47d - Mammary gland"	"Cluster 52: Non-specific - Transcription"	Nucleoplasm	Cytosol	"HPA071568: "	"prognostic favorable (7.39e-4)"	"unprognostic (1.99e-1)"	"prognostic unfavorable (2.74e-4)"	"prognostic favorable (4.25e-7)"	"unprognostic (5.95e-2)"	"unprognostic (7.96e-3)"	"unprognostic (2.72e-2)"	"unprognostic (1.51e-1)"	"prognostic unfavorable (2.13e-4)"	"unprognostic (3.89e-2)"	"unprognostic (8.24e-3)"	"unprognostic (5.14e-3)"	"unprognostic (8.66e-2)"	"unprognostic (1.98e-1)"	"unprognostic (3.82e-1)"	"unprognostic (4.14e-2)"	"unprognostic (5.44e-2)"	12.4	19.4	7.8	8.9	9.4	13.5	16.8	15.8	10.0	23.4	5.1	14.7	6.6	18.4	6.7	17.0	20.2	4.7	16.0	9.3	5.3	10.4	21.2	12.5	11.7	9.2	7.3	17.8	13.7	6.6	18.4	9.5	7.5	25.6	2.9	14.7	14.1	7.4	32.2	21.7	13.8	4.9	4.7	22.1	12.6	16.1	8.8	8.8	29.4	8.3	7.2	13.4	18.2	11.9	16.1	5.5	12.8	15.4	7.3	7.2	25.7	7.9	5.8	6.8	8.5	9.6	4.4	22.4	8.2	9.1	5.5	8.9	7.8	9.3	4.2	10.1	19.9	7.5	9.9	8.0	13.6	7.6	16.7	11.2	9.9	5.6	4.7	12.3	9.3	12.4	18.7	13.3	6.2	8.3	8.8	11.5	11.3	5.8	13.6	14.7	9.7	19.0	6.8	10.5	23.7	18.1	10.3	11.2	12.5	12.3	61.5	19.7	13.5	10.1	5.7	12.5	8.0	36.5	16.4	17.1	20.0	15.1	6.0	1.5	0.6	1.9	0.3	0.2	0.2	4.2	0.2	0.2	0.3	5.1	0.4	0.5	4.7	0.8	0.3	1.7	0.4	0.3	7.8	9.4	15.8	10.0	9.3	5.3	9.2	7.3	7.5	4.7	8.8	11.9	15.3	6.4	10.4	18.9	73.2	7.4	14.1	10.8	7.4	72.5	36.1	22.2	15.3	10.0	9.4	7.3	98.0	25.7	25.5	15.3	7.9	10.5	17.0	25.4	18.7	16.4	8.4	9.4	33.6	7.6	26.2	14.6	26.5	30.2	8.2	34.3	15.4	30.9	9.0	74.0	30.6	16.7	16.2	14.2	7.8	12.1	18.3	15.8	10.6	27.2	17.0	23.5	19.6	29.7	28.7	18.0	14.1	23.3	23.9	19.3	7.4	6.6	11.7	69.2	6.6	23.1	13.7	25.2	9.1	14.1	15.3	24.1	13.9	29.7	9.5	12.9
KDM4C	"GASC1, JMJD2C, KIAA0780, TDRD14C"	ENSG00000107077	"Lysine demethylase 4C"	Q9H3R0	9	6720863-7175648	"Enzymes, Plasma proteins, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 206.9;Inhibitory neurons: 235.9;Microglial cells: 148.0;Oligodendrocyte precursor cells: 189.0;Oligodendrocytes: 347.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HDLM-2: 60.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA069357			Approved	Nucleoplasm		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 34: Non-specific - Transcription"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	Nucleoplasm		"HPA069357: AB_2686128"	"unprognostic (1.56e-2)"	"unprognostic (1.91e-2)"	"unprognostic (4.38e-2)"	"unprognostic (1.38e-1)"	"unprognostic (3.52e-1)"	"unprognostic (4.36e-2)"	"unprognostic (2.50e-2)"	"unprognostic (6.89e-3)"	"unprognostic (2.37e-1)"	"unprognostic (2.34e-2)"	"unprognostic (3.65e-2)"	"unprognostic (2.03e-2)"	"unprognostic (1.92e-1)"	"unprognostic (7.87e-3)"	"unprognostic (1.21e-1)"	"unprognostic (2.23e-2)"	"unprognostic (1.64e-3)"	10.0	9.6	9.8	12.8	12.0	30.1	11.3	30.6	11.5	10.2	13.5	13.7	13.1	10.4	11.8	10.1	10.3	9.7	7.8	9.9	11.1	8.7	11.1	10.6	19.1	13.8	11.7	11.5	16.1	17.8	11.8	8.9	13.3	9.9	16.1	28.9	11.6	8.8	8.3	15.2	14.4	10.8	9.7	13.9	15.1	9.8	11.9	23.6	13.4	6.0	18.8	10.3	10.7	16.4	17.2	9.8	4.0	6.0	13.4	14.3	11.8	7.6	9.6	8.5	8.1	11.3	9.1	20.1	4.6	10.3	8.7	5.1	8.6	12.8	11.1	60.6	7.4	27.9	13.8	15.1	12.4	10.8	18.5	12.5	8.4	6.7	14.0	21.1	10.4	16.4	4.7	13.4	9.3	8.3	18.0	40.4	7.0	18.0	3.8	10.8	3.4	12.9	12.3	9.2	14.0	8.3	7.1	12.7	6.8	10.7	6.6	17.5	11.0	8.4	4.0	9.9	7.5	10.2	8.1	21.3	8.2	10.0	3.3	7.5	7.1	13.5	9.6	7.7	11.2	12.1	10.4	11.2	9.6	13.8	11.3	8.8	1.6	11.2	13.1	3.7	10.0	8.0	9.8	12.0	30.6	11.5	9.9	11.1	13.8	11.7	13.3	9.7	11.9	16.4	11.3	6.4	14.4	110.4	40.6	19.9	7.9	10.5	18.8	22.6	11.2	8.0	9.2	11.5	9.2	7.3	45.9	5.2	22.7	10.3	3.9	7.0	84.8	10.0	12.2	9.4	9.7	42.1	206.9	6.2	5.3	6.9	34.7	16.8	8.8	6.0	6.8	13.0	6.7	11.8	235.9	14.7	6.1	10.0	19.4	83.3	9.6	16.5	7.2	148.0	15.0	3.3	19.6	189.0	347.2	7.6	9.5	9.4	27.1	6.2	14.1	4.0	10.8	28.3	13.1	7.3	7.6	6.6	5.4	14.4	23.9	5.9	28.2	6.2	8.1	8.0
KDM4D	"FLJ10251, JMJD2D"	ENSG00000186280	"Lysine demethylase 4D"	Q6B0I6	11	94973709-94999519	"Enzymes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	15	"testis: 33.3"	"Group enriched"	"Detected in many"	7	"Early spermatids: 115.7;Late spermatids: 43.7;Spermatocytes: 102.5"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Immune cell enhanced"	"Detected in single"		"non-classical monocyte: 2.1"	"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"HPA055854, HPA064037"	Approved		Approved	Nucleoplasm		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 74: Testis - Spermatogenesis"	"Cluster 23: AN3-CA - Transcription regulation"	"Cluster 66: Spermatocytes - Spermatogenesis"	Nucleoplasm		"HPA055854: AB_2682944, HPA064037: AB_2685180"	"unprognostic (1.98e-1)"	"unprognostic (5.71e-2)"	"unprognostic (1.83e-1)"	"unprognostic (9.65e-3)"	"unprognostic (3.19e-1)"	"unprognostic (5.12e-2)"	"unprognostic (2.84e-2)"	"unprognostic (3.16e-1)"	"unprognostic (3.11e-1)"	"unprognostic (1.36e-1)"	"unprognostic (1.37e-2)"	"unprognostic (5.62e-2)"	"unprognostic (4.49e-2)"	"unprognostic (8.14e-2)"	"unprognostic (1.84e-1)"	"unprognostic (2.45e-1)"	"unprognostic (2.88e-1)"	0.5	0.6	0.5	0.3	0.5	0.0	0.8	0.5	0.6	0.5	0.4	0.2	0.1	0.5	0.8	0.3	1.0	0.4	1.0	0.5	0.5	0.5	0.3	0.4	0.7	0.5	0.5	0.9	0.3	0.9	0.5	0.4	0.4	0.5	0.3	2.1	0.6	0.6	0.6	0.7	0.3	0.5	0.6	0.6	0.3	33.3	0.5	0.6	0.7	0.7	0.6	0.4	0.3	0.6	0.5	0.8	3.3	2.4	0.7	0.8	1.5	1.1	1.2	3.0	2.6	0.9	1.0	1.2	3.5	0.9	2.9	1.0	2.1	2.3	2.3	1.4	2.2	1.1	0.4	1.3	0.6	0.5	0.3	1.5	1.2	3.0	2.7	0.4	1.1	4.4	1.2	0.5	1.2	1.0	1.9	1.2	1.4	0.8	4.0	2.6	1.4	0.9	0.7	0.3	1.9	2.3	1.3	1.1	0.9	1.7	1.2	0.4	0.9	2.0	1.2	3.2	1.7	0.7	2.5	0.2	0.7	0.6	2.3	0.0	0.1	0.0	0.1	0.0	0.0	0.4	0.2	0.3	0.0	0.0	0.2	0.0	0.0	0.0	2.1	0.4	0.6	0.1	0.5	0.5	0.5	0.6	0.5	0.5	0.5	0.5	0.4	0.6	0.5	0.6	0.8	0.0	0.0	2.6	0.2	0.0	0.2	0.8	0.6	7.0	0.8	0.9	1.1	1.5	0.4	0.0	2.1	0.9	1.6	0.0	3.9	0.8	115.7	1.3	1.4	1.1	0.0	0.4	1.8	0.6	0.9	0.9	0.5	0.4	0.0	2.6	2.2	1.3	0.7	3.3	2.6	0.1	0.0	0.6	0.3	43.7	2.1	0.8	0.0	4.7	0.7	3.9	1.0	3.5	4.3	0.2	0.1	1.2	0.5	0.2	0.0	1.3	1.0	3.3	0.0	0.8	0.7	102.5	11.4	0.7	0.0	0.3	0.3	2.5	0.3	0.2
KDM4E	"JMJD2E, KDM4DL, KDM5E"	ENSG00000235268	"Lysine demethylase 4E"	B2RXH2	11	95025258-95027596	"Enzymes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"No human protein/transcript evidence"	"Evidence at protein level"	"Evidence at protein level"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"											"HPA051740, HPA054225"	Uncertain					NA	NA									"HPA051740: AB_2681586, HPA054225: AB_2682421"	"unprognostic (1.32e-1)"										"unprognostic (6.31e-2)"	"unprognostic (4.74e-2)"	"unprognostic (3.69e-1)"	"unprognostic (9.27e-2)"	"unprognostic (5.54e-2)"	"unprognostic (8.10e-4)"		0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.1	0.0	0.0	0.2	0.0	0.0	0.2	0.0	0.0	0.0	0.1	0.0	0.3	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.1	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
KDM5A	"JARID1A, RBBP2"	ENSG00000073614	"Lysine demethylase 5A"	P29375	12	280057-389320	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors"	"Biological rhythms, Transcription, Transcription regulation"	"Activator, Chromatin regulator, Developmental protein, Dioxygenase, Oxidoreductase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 45.5"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA006201			Supported	"Nuclear bodies,Cytosol"		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 5: NTERA-2 - Transcription"	"Cluster 65: Plasmacytoid DCs - Unknown function"	"Nuclear bodies"	Cytosol	"HPA006201: AB_1079160"	"unprognostic (2.75e-1)"	"unprognostic (1.68e-1)"	"unprognostic (1.83e-1)"	"unprognostic (1.12e-1)"	"unprognostic (4.46e-2)"	"unprognostic (1.60e-1)"	"unprognostic (3.53e-3)"	"unprognostic (1.81e-2)"	"unprognostic (5.81e-2)"	"unprognostic (3.19e-1)"	"unprognostic (1.77e-3)"	"unprognostic (6.11e-2)"	"unprognostic (1.79e-2)"	"unprognostic (1.10e-1)"	"unprognostic (1.52e-1)"	"unprognostic (2.60e-2)"	"unprognostic (7.69e-2)"	8.1	8.7	5.8	11.4	8.3	45.5	11.1	11.6	8.5	8.6	10.0	8.2	7.2	9.7	7.1	8.9	7.6	8.0	5.2	6.2	6.5	7.8	9.9	8.8	15.3	6.8	5.7	11.0	9.4	10.1	4.2	11.8	6.5	8.6	9.9	9.6	6.7	7.3	5.5	12.5	7.3	9.4	6.0	13.5	8.8	21.1	6.7	21.6	9.1	7.6	14.4	8.7	7.2	15.0	14.4	25.3	18.3	14.2	16.1	15.2	20.3	12.5	16.5	18.4	19.8	15.2	17.0	24.0	3.9	21.0	16.0	13.3	19.2	14.2	21.9	37.9	15.9	29.3	26.5	9.0	13.0	38.6	22.1	16.6	13.1	22.6	29.9	18.8	18.8	21.0	17.9	32.7	15.7	9.7	27.9	11.0	28.4	12.3	7.9	25.7	47.5	11.4	8.8	32.6	7.0	20.5	24.5	11.0	13.0	25.0	11.9	24.0	26.0	12.0	17.0	13.6	21.1	11.5	13.6	53.7	15.5	16.5	18.0	64.5	21.8	44.4	31.4	25.0	32.3	27.1	24.6	25.9	22.8	32.0	26.3	22.8	63.0	35.8	28.9	32.0	20.9	22.5	5.8	8.3	11.6	8.5	6.2	6.5	6.8	5.7	6.5	6.0	6.7	15.0	53.1	64.1	61.6	61.7	80.6	33.0	22.2	30.1	48.9	69.0	35.3	27.9	38.2	31.5	39.0	35.0	116.7	48.8	103.3	51.3	3.9	37.4	96.8	60.2	72.8	51.6	69.7	51.3	71.7	31.6	34.7	47.2	39.8	99.8	54.4	106.9	42.8	30.9	30.2	87.5	59.1	40.0	40.7	52.5	37.5	32.5	48.4	63.9	26.6	57.1	82.9	48.3	105.0	68.3	85.9	38.7	37.0	55.7	73.1	32.4	33.6	11.8	40.2	71.9	59.2	64.0	59.9	137.1	104.8	50.1	47.6	71.1	80.1	67.5	40.1	42.0
KDM5B	"CT31, JARID1B, PLU-1, PPP1R98, RBBP2H1A"	ENSG00000117139	"Lysine demethylase 5B"	Q9UGL1	1	202724495-202808487	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors"	"Biological rhythms, Transcription, Transcription regulation"	"Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor"	"Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"testis: 62.3"	"Cell type enhanced"	"Detected in all"		"Late spermatids: 243.6;Spermatocytes: 390.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA027179, HPA053723, CAB068193"	Enhanced		Supported	Nucleoplasm,Cytosol		NA	Yes			"Cluster 10: Basophils - Unknown function"	"Cluster 71: Testis - DNA repair"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 66: Spermatocytes - Spermatogenesis"	Nucleoplasm	Cytosol	"CAB068193: AB_2665696, HPA027179: AB_1851987, HPA053723: AB_2682241"	"unprognostic (1.19e-1)"	"unprognostic (1.74e-2)"	"unprognostic (1.03e-1)"	"unprognostic (4.67e-2)"	"unprognostic (1.92e-2)"	"unprognostic (2.31e-1)"	"unprognostic (3.49e-3)"	"unprognostic (3.02e-2)"	"unprognostic (3.23e-2)"	"unprognostic (6.12e-2)"	"unprognostic (1.61e-2)"	"unprognostic (4.79e-2)"	"unprognostic (8.25e-3)"	"unprognostic (2.56e-2)"	"unprognostic (1.61e-1)"	"unprognostic (5.56e-2)"	"unprognostic (4.13e-1)"	9.1	7.7	1.5	2.6	2.2	14.1	9.9	5.8	4.8	14.7	7.9	10.6	2.1	12.6	3.3	21.0	9.9	2.9	6.0	4.6	1.5	6.2	4.6	10.8	2.2	0.8	0.4	12.8	8.3	2.6	6.9	4.7	0.2	10.6	2.2	17.8	12.5	2.4	4.7	24.3	8.6	3.1	1.0	7.4	8.7	62.3	1.2	4.1	8.4	0.8	2.1	10.9	15.7	2.3	9.9	2.4	14.0	9.8	7.2	6.6	23.7	6.2	9.4	6.2	6.4	2.2	8.8	0.1	5.7	7.9	2.3	11.8	9.0	8.3	5.4	0.5	12.8	7.7	2.4	1.9	5.5	17.7	8.9	9.4	12.1	7.0	7.2	10.1	11.7	7.3	20.9	0.3	4.9	6.3	5.8	16.4	21.9	4.3	28.0	18.7	0.1	0.4	6.5	10.7	10.7	23.4	14.7	7.9	8.7	15.7	16.6	10.5	12.8	8.2	5.8	1.4	5.2	2.3	1.1	8.2	6.0	5.5	4.1	44.6	6.4	19.6	7.7	4.8	4.6	10.9	8.9	4.3	4.2	17.4	9.6	6.0	34.4	12.9	10.4	6.6	7.2	3.9	1.5	2.2	5.8	4.8	4.6	1.5	0.8	0.4	0.2	1.0	1.2	2.3	24.5	89.8	38.5	46.7	22.2	64.4	34.8	53.0	84.2	35.5	57.1	50.0	9.5	11.5	53.6	16.5	62.6	41.8	12.4	23.7	5.9	47.6	191.6	65.2	71.8	31.9	43.6	50.2	75.8	22.3	34.3	42.7	47.9	69.5	27.1	28.6	17.2	10.9	7.7	15.2	53.5	38.1	44.7	15.1	21.9	243.6	36.4	15.5	26.6	40.3	11.3	69.8	10.3	39.7	42.5	45.4	21.8	32.7	25.8	43.1	15.2	8.2	61.9	138.6	32.9	22.8	40.2	390.9	71.0	95.9	116.2	82.4	21.2	61.5	30.2	55.6
KDM5C	"DXS1272E, JARID1C, MRX13, SMCX, XE169"	ENSG00000126012	"Lysine demethylase 5C"	P41229	X	53191321-53225422	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors"	"Biological rhythms, Transcription, Transcription regulation"	"Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA038244, HPA046147"			Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 59: Non-specific - Translation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 44: Endometrium - Transcription"	Nucleoplasm	Cytosol	"HPA038244: AB_2675911, HPA046147: AB_2679555"	"unprognostic (1.19e-1)"	"unprognostic (1.13e-1)"	"unprognostic (1.56e-2)"	"unprognostic (7.10e-2)"	"unprognostic (9.75e-2)"	"unprognostic (2.19e-1)"	"prognostic unfavorable (2.11e-4)"	"unprognostic (2.08e-2)"	"unprognostic (2.11e-1)"	"unprognostic (1.24e-1)"	"unprognostic (5.45e-2)"	"unprognostic (1.58e-2)"	"unprognostic (5.05e-3)"	"unprognostic (1.96e-2)"	"unprognostic (6.91e-2)"	"unprognostic (1.30e-1)"	"unprognostic (1.00e-1)"	22.3	29.0	19.2	28.2	19.7	34.8	22.7	23.0	21.7	35.5	22.2	25.5	26.0	35.5	14.8	35.2	33.2	17.1	22.7	19.6	20.1	21.1	24.1	27.2	33.4	19.8	19.0	39.9	26.4	33.8	31.4	23.8	19.0	23.8	15.4	24.6	29.4	18.5	51.0	34.2	28.2	26.9	16.8	30.9	25.8	13.5	20.9	44.2	27.6	25.5	26.5	25.9	35.4	20.8	45.3	60.4	63.6	49.0	43.2	39.1	45.2	27.7	32.2	36.8	34.0	41.3	28.9	41.8	35.0	36.7	103.2	39.5	72.6	59.1	27.8	31.6	107.9	40.6	66.7	29.6	52.9	48.5	77.6	31.0	42.8	72.0	87.7	52.3	55.2	34.2	80.8	27.2	27.3	57.9	35.9	55.4	54.1	23.3	56.3	40.1	37.8	45.9	23.5	42.6	47.6	61.4	84.0	76.8	32.2	58.4	53.9	42.3	37.8	40.6	35.0	36.9	27.2	39.0	34.2	31.5	52.6	56.9	30.8	0.9	1.2	0.8	1.6	1.1	1.4	1.2	1.0	1.6	0.9	0.8	1.2	0.8	1.4	0.8	1.2	1.3	1.3	1.2	19.2	19.7	23.0	21.7	19.6	20.1	19.8	19.0	19.0	16.8	20.9	20.8	17.6	12.8	14.9	33.0	17.8	12.1	10.5	12.1	14.8	24.7	19.7	15.0	10.0	11.5	15.2	7.3	25.0	13.1	21.2	32.2	3.9	15.0	0.8	28.2	25.2	17.7	31.2	17.2	36.1	21.9	15.1	14.2	21.4	35.7	13.3	25.5	15.0	25.5	14.4	25.2	37.0	25.8	16.2	18.2	8.8	2.6	14.6	17.1	14.2	27.2	14.9	9.8	16.5	31.2	49.2	26.4	26.3	15.8	17.0	17.9	22.1	5.8	16.4	16.9	0.0	17.2	16.8	10.3	15.8	16.2	15.9	20.8	18.0	22.6	18.9	21.6
KDM5D	"HY, HYA, JARID1D, KIAA0234, SMCY"	ENSG00000012817	"Lysine demethylase 5D"	Q9BY66	Y	19703865-19744939	"Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Chromatin regulator, Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Plasma cells: 46.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"HEL: 60.4;U-698: 51.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			HPA049086			Approved	"Nucleoli fibrillar center"		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 64: Macrophages - Immune response"	"Cluster 36: HEL - Hemostasis"	"Cluster 63: NK-cells & T-cells - Immune response"	"Nucleoli fibrillar center"		"HPA049086: "			"unprognostic (8.38e-2)"		"unprognostic (2.20e-1)"	"prognostic favorable (3.58e-5)"	"unprognostic (6.08e-3)"	"unprognostic (1.50e-2)"	"unprognostic (3.10e-2)"		"unprognostic (4.57e-2)"	"unprognostic (1.22e-1)"	"unprognostic (1.15e-2)"	"unprognostic (4.00e-2)"	"unprognostic (7.92e-2)"	"unprognostic (1.30e-2)"	"unprognostic (1.80e-2)"	16.0	29.9	2.3	11.8	2.4	17.4	12.8	3.2	13.2	0.0	5.3	22.2	18.0	0.0	15.2	12.3	0.0	11.7	13.3	2.2	2.5	12.1	12.7	16.7	8.7	2.9	2.0	0.0	18.9	4.9	16.2	9.2	2.8	25.5	21.6	9.0	15.6	18.0	15.7	12.9	35.2	0.0	1.6	30.8	16.0	12.1	2.6	0.0	18.6	25.7	20.5	19.9	0.0	4.4	0.1	8.0	0.0	0.0	0.0	0.0	15.9	15.4	12.9	8.6	9.4	0.0	0.0	0.3	0.0	12.6	0.0	0.0	0.0	0.0	9.4	22.6	0.0	60.4	0.0	18.5	11.5	0.1	0.0	12.9	12.9	0.0	0.0	0.0	0.0	10.6	0.0	0.0	20.1	0.0	24.6	0.1	11.6	0.0	0.1	0.0	10.1	10.9	17.0	28.7	13.2	0.1	0.0	0.0	5.9	27.2	0.0	12.5	18.9	25.9	0.2	0.2	6.6	24.2	16.6	51.4	2.5	0.1	0.0	0.0	1.8	2.1	2.3	1.1	1.7	3.2	2.2	2.2	1.7	2.6	2.4	1.9	0.2	1.9	0.9	2.6	1.8	1.3	2.3	2.4	3.2	13.2	2.2	2.5	2.9	2.0	2.8	1.6	2.6	4.4	0.0	19.2	16.5	9.4	22.2	6.4	9.2	5.3	18.2	39.9	0.0	0.0	12.2	2.8	7.7	18.4	20.9	7.0	14.6	2.8	5.9	5.4	0.8	0.0	0.0	10.8	3.5	22.7	26.0	0.0	2.5	10.6	19.9	0.0	11.4	0.0	13.2	3.1	4.8	13.5	23.2	5.8	2.0	7.6	12.1	3.8	36.7	10.3	10.6	10.3	14.5	7.5	13.4	12.1	15.2	1.7	5.0	33.8	46.3	8.6	13.9	4.2	5.5	30.5	26.3	8.5	8.5	3.3	9.7	12.2	10.9	5.6	16.4	0.0	6.6	8.8
KDM6A	UTX	ENSG00000147050	"Lysine demethylase 6A"	O15550	X	44873188-45112779	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		"Chromatin regulator, Dioxygenase, Oxidoreductase"	"Cancer-related genes, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Microglial cells: 116.2;Oligodendrocyte precursor cells: 118.1;Oligodendrocytes: 264.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000568, HPA001165, HPA002111"	Enhanced		Approved	"Nucleoplasm,Nucleoli,Nucleoli rim"	"Intracellular and membrane"	NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 71: Testis - DNA repair"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 44: Endometrium - Transcription"	"Nucleoli, Nucleoli rim"	Nucleoplasm	"HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704"	"unprognostic (1.73e-3)"	"unprognostic (6.86e-3)"	"unprognostic (1.45e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.72e-1)"	"unprognostic (2.65e-2)"	"unprognostic (2.58e-3)"	"unprognostic (8.22e-3)"	"unprognostic (3.23e-1)"	"unprognostic (2.44e-1)"	"unprognostic (2.56e-1)"	"unprognostic (1.07e-1)"	"unprognostic (2.73e-1)"	"unprognostic (2.24e-2)"	"unprognostic (5.18e-2)"	"unprognostic (1.26e-1)"	"unprognostic (3.16e-2)"	9.6	8.0	6.7	4.5	7.6	19.4	10.6	7.2	10.6	15.7	6.5	9.1	6.2	14.0	5.1	11.1	14.0	3.4	6.6	6.8	6.9	6.8	10.4	10.8	8.0	7.3	6.8	17.2	10.8	6.4	8.6	3.9	7.3	7.7	4.1	3.8	10.5	3.1	10.4	18.4	13.0	4.1	7.1	14.1	12.5	12.2	7.0	12.9	9.4	6.1	5.3	9.8	15.2	9.9	7.3	5.8	7.0	9.3	5.0	6.8	15.7	4.9	4.2	4.0	4.1	10.4	5.2	4.6	3.2	3.5	10.1	13.9	6.5	5.4	3.9	7.6	10.8	2.4	4.5	5.2	3.7	2.6	13.2	2.6	6.4	8.2	6.6	5.1	4.2	5.3	6.4	10.1	2.4	6.0	6.9	13.6	6.8	4.2	7.4	6.4	7.1	1.4	3.8	9.2	6.2	4.4	18.2	6.8	10.7	14.1	8.5	0.0	3.0	5.4	5.2	5.2	3.6	5.5	8.8	5.6	4.0	3.3	3.3	7.3	1.7	1.5	1.9	3.5	2.1	1.9	2.5	2.8	3.1	1.2	2.5	2.4	2.8	2.8	3.0	1.7	2.2	2.0	6.7	7.6	7.2	10.6	6.8	6.9	7.3	6.8	7.3	7.1	7.0	9.9	23.2	6.4	10.6	92.1	26.0	26.1	14.3	9.4	38.1	7.7	16.8	12.1	12.8	12.8	10.9	7.3	14.6	4.5	26.1	24.6	0.0	8.4	1.5	26.4	25.5	13.1	13.1	16.8	88.3	7.5	7.9	14.2	23.0	39.7	2.5	27.3	6.4	17.6	7.0	25.2	74.0	14.0	6.1	9.1	13.8	2.0	6.5	19.9	10.6	116.2	12.6	6.8	6.2	118.1	264.6	9.1	17.4	7.2	31.4	14.2	22.6	3.7	8.9	9.7	6.6	20.9	17.0	14.1	12.5	29.3	26.3	10.9	27.4	10.6	13.1	17.1
KDM6B	"JMJD3, KIAA0346"	ENSG00000132510	"Lysine demethylase 6B"	O15054	17	7834217-7854796	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Inflammatory response"	"Chromatin regulator, Dioxygenase, Oxidoreductase"	"Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Langerhans cells: 393.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	6	"basophil: 3.6;neutrophil: 8.9"	"Lineage enriched"	"Detected in single"	12	"granulocytes: 8.9"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA037988	Supported		Approved	"Nuclear speckles"		NA	NA			"Cluster 50: Neutrophils - Cellular senescence"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 23: AN3-CA - Transcription regulation"	"Cluster 41: Macrophages - Immune response"	"Nuclear speckles"		"HPA037988: AB_10672502"	"unprognostic (3.43e-1)"	"unprognostic (3.43e-1)"	"unprognostic (1.09e-1)"	"unprognostic (2.13e-3)"	"unprognostic (1.14e-1)"	"unprognostic (1.59e-1)"	"unprognostic (1.21e-1)"	"unprognostic (2.43e-1)"	"unprognostic (9.89e-2)"	"unprognostic (8.00e-2)"	"unprognostic (1.47e-3)"	"unprognostic (1.42e-2)"	"prognostic favorable (6.07e-4)"	"unprognostic (5.73e-2)"	"unprognostic (1.56e-1)"	"prognostic unfavorable (3.37e-4)"	"unprognostic (1.85e-1)"	33.6	13.3	3.1	20.0	2.4	35.5	12.6	12.5	22.9	12.2	3.4	15.4	14.3	14.0	3.4	13.6	17.1	15.6	17.7	3.2	4.5	14.6	15.2	27.4	8.0	4.8	3.2	29.7	17.1	7.9	21.8	6.8	3.3	14.5	4.1	6.2	12.0	6.2	12.4	16.4	17.5	5.5	1.4	20.7	17.7	16.1	5.0	16.4	15.9	8.2	4.6	19.8	12.4	6.2	4.9	7.0	12.5	19.0	4.6	3.4	16.2	3.8	5.4	2.7	2.8	9.3	3.6	11.4	4.5	3.0	3.9	12.2	5.8	5.1	1.6	4.7	4.5	5.3	6.7	6.2	13.0	7.2	15.6	5.3	8.0	6.1	5.1	7.2	4.8	11.8	8.8	4.8	1.2	7.7	10.6	6.5	6.4	4.9	3.9	11.9	2.9	3.2	5.1	7.7	6.6	21.4	4.8	11.5	10.3	7.3	6.4	8.9	2.3	4.0	7.1	7.0	5.5	5.6	1.2	3.9	5.3	4.2	8.1	3.6	0.6	1.1	0.3	0.4	0.3	0.3	0.2	0.1	0.3	0.5	0.3	0.4	8.9	0.1	0.2	0.7	0.1	0.4	3.1	2.4	12.5	22.9	3.2	4.5	4.8	3.2	3.3	1.4	5.0	6.2	135.5	25.6	33.6	6.2	158.8	214.4	122.2	30.8	156.0	45.2	113.7	70.9	10.8	42.9	32.4	7.3	31.3	15.1	127.6	47.8	1.9	28.0	29.2	88.2	67.1	80.5	79.9	8.4	9.0	25.1	15.9	85.4	73.4	181.6	178.6	44.8	34.2	22.7	23.4	38.7	10.9	62.5	18.3	50.4	393.1	10.7	16.4	219.2	56.9	4.7	25.6	13.2	9.2	5.5	1.9	58.4	49.1	13.9	70.7	99.6	53.9	9.8	20.5	17.1	19.7	181.2	83.0	20.1	19.3	138.1	188.0	52.0	104.1	22.0	46.2	86.6
KDM8	"FLJ13798, JMJD5"	ENSG00000155666	"Lysine demethylase 8"	Q8N371	16	27203508-27221768	"Enzymes, Predicted intracellular proteins"	"Biological rhythms, Cell cycle, Transcription, Transcription regulation"	"Aminopeptidase, Chromatin regulator, Dioxygenase, Hydrolase, Oxidoreductase, Protease"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	6	"liver: 80.3"	"Group enriched"	"Detected in many"	6	"Hepatocytes: 56.4;Proximal enterocytes: 25.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA026545	Approved		Approved	Nucleoplasm,Cytosol		NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 2: Hepatocytes - Metabolism"	Nucleoplasm	Cytosol	"HPA026545: AB_1852015"	"unprognostic (1.39e-1)"	"unprognostic (1.37e-3)"	"unprognostic (2.80e-1)"	"unprognostic (2.16e-2)"	"unprognostic (3.21e-1)"	"unprognostic (1.22e-2)"	"unprognostic (2.41e-3)"	"unprognostic (1.33e-2)"	"unprognostic (7.95e-2)"	"unprognostic (3.41e-1)"	"prognostic favorable (1.75e-4)"	"unprognostic (1.22e-1)"	"unprognostic (2.75e-2)"	"unprognostic (5.33e-2)"	"unprognostic (2.71e-1)"	"unprognostic (2.04e-1)"	"unprognostic (3.92e-3)"	2.1	3.5	4.0	3.1	4.0	1.3	2.2	5.3	4.2	2.6	3.2	2.7	13.3	3.0	1.8	2.0	2.5	2.2	2.4	4.1	4.0	3.0	80.3	2.2	3.4	3.7	3.5	3.0	5.1	2.4	4.0	1.5	3.9	3.6	1.7	2.3	2.3	2.1	4.6	1.7	12.5	1.6	3.6	4.6	2.6	2.7	3.8	3.5	3.1	3.0	2.6	2.7	2.3	4.1	1.4	3.0	5.0	2.7	1.1	1.5	2.7	1.7	1.9	3.8	3.3	2.6	2.4	7.6	2.9	2.5	1.9	1.6	3.0	2.7	2.2	9.2	4.4	4.9	3.3	6.2	2.7	3.6	5.5	1.9	2.1	2.4	1.7	2.2	3.1	3.5	6.1	4.8	2.4	2.3	3.4	6.4	8.5	1.1	1.8	5.2	3.1	6.9	1.4	1.6	4.8	2.9	0.7	2.5	1.9	1.7	2.7	4.8	3.4	4.5	2.2	1.7	1.8	2.9	3.1	6.3	1.9	3.3	0.4	0.2	2.1	0.8	2.5	1.9	2.1	1.9	3.6	3.5	1.9	4.3	3.4	4.9	0.1	1.3	1.9	4.0	2.3	2.3	4.0	4.0	5.3	4.2	4.1	4.0	3.7	3.5	3.9	3.6	3.8	4.1	0.7	0.0	1.7	3.3	2.4	0.3	0.2	0.7	3.4	1.9	0.7	0.6	1.5	1.5	1.6	0.0	2.1	2.0	2.4	1.0	3.9	1.3	0.6	0.5	1.2	1.6	5.4	0.8	2.4	0.7	0.7	1.0	3.1	0.4	0.0	1.5	1.1	56.4	2.0	0.0	2.5	1.6	2.0	1.9	1.2	0.9	0.3	1.3	0.0	1.9	1.4	1.4	1.0	1.5	3.2	0.7	0.5	1.2	3.0	0.5	25.4	1.4	5.9	2.5	0.0	0.9	1.4	1.1	2.5	0.6	0.0	1.4	2.0	1.6	1.2	0.2
KDSR	"DHSR, FVT1, SDR35C1"	ENSG00000119537	"3-ketodihydrosphingosine reductase"	Q06136	18	63327726-63367228	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid metabolism, Sphingolipid metabolism"	Oxidoreductase	"Cancer-related genes, Disease variant, Palmoplantar keratoderma, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"U-266/70: 90.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB003673, HPA044884"	Approved					NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 29: U-266 - Adaptive immune response"	"Cluster 22: Epithelial cell types - Mixed function"			"CAB003673: AB_425440, HPA044884: AB_2679131"	"unprognostic (4.44e-2)"	"unprognostic (8.57e-2)"	"unprognostic (2.52e-2)"	"unprognostic (4.56e-2)"	"unprognostic (5.88e-3)"	"unprognostic (7.50e-3)"	"unprognostic (1.80e-2)"	"unprognostic (2.66e-1)"	"unprognostic (2.97e-1)"	"unprognostic (1.97e-1)"	"unprognostic (2.70e-2)"	"unprognostic (6.81e-2)"	"prognostic favorable (9.53e-6)"	"unprognostic (3.32e-2)"	"unprognostic (5.77e-2)"	"unprognostic (2.22e-1)"	"unprognostic (2.16e-3)"	32.3	22.4	12.8	8.1	19.9	4.8	25.4	19.5	16.7	26.9	12.3	24.6	7.0	22.7	20.8	22.4	18.9	12.6	20.7	12.7	16.4	20.1	36.7	21.5	7.0	20.6	17.7	21.3	15.7	13.1	12.1	8.5	20.0	16.3	7.4	7.0	22.8	11.6	16.7	44.5	15.1	13.3	17.6	8.4	16.4	6.1	16.6	7.1	17.2	8.9	6.8	23.9	23.4	22.4	14.9	6.5	6.7	7.5	52.6	39.0	13.0	48.8	29.7	10.5	13.9	2.7	10.0	15.1	20.3	19.1	17.4	64.6	8.7	27.3	12.8	28.6	14.5	11.6	8.7	3.4	40.1	22.0	7.8	37.4	50.7	16.8	47.9	19.3	10.5	9.9	9.5	21.0	28.1	6.2	23.6	9.7	8.0	3.7	23.5	15.5	19.7	21.9	29.0	9.6	8.5	16.4	23.4	11.3	21.9	8.8	6.1	12.1	24.9	44.0	10.6	14.8	21.3	90.4	44.9	8.7	33.2	13.0	13.4	0.1	5.2	0.5	6.5	8.1	26.6	5.7	13.6	10.2	8.0	4.7	9.3	6.1	1.3	14.2	3.9	3.8	19.1	5.3	12.8	19.9	19.5	16.7	12.7	16.4	20.6	17.7	20.0	17.6	16.6	22.4	53.1	35.3	49.1	21.9	30.1	158.6	131.7	47.0	122.3	37.4	63.4	63.6	27.7	62.9	43.5	38.6	27.1	58.8	15.6	34.6	15.6	50.7	1.0	43.9	53.0	48.1	20.4	17.4	19.1	36.7	70.4	82.0	26.5	64.9	26.0	52.3	51.8	88.3	36.4	40.4	24.2	31.8	42.7	32.2	47.7	6.5	71.1	39.9	56.9	14.0	31.5	56.5	13.4	21.6	57.0	47.4	44.6	70.7	24.5	104.3	43.4	39.6	41.2	41.1	32.9	73.7	48.4	1.3	5.2	89.7	143.1	91.4	37.7	51.1	40.3	94.7
KMO		ENSG00000117009	"Kynurenine 3-monooxygenase"	O15229	1	241532134-241595642	"Enzymes, Metabolic proteins, Predicted membrane proteins"	"Pyridine nucleotide biosynthesis"	"Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"kidney: 31.5;liver: 91.7"	"Cell type enhanced"	"Detected in many"		"B-cells: 33.8;Hepatocytes: 46.9;Langerhans cells: 49.4;Macrophages: 33.0;Proximal tubular cells: 63.2;Syncytiotrophoblasts: 180.1"	"Group enriched"	"Detected in many"	4	"breast cancer: 1.6;liver cancer: 3.3;renal cancer: 3.3"	"Low region specificity"	"Detected in single"			"Group enriched"	"Detected in many"	79	"classical monocyte: 11.0;intermediate monocyte: 32.3;memory B-cell: 36.1;myeloid DC: 11.3;naive B-cell: 42.0;non-classical monocyte: 33.8;plasmacytoid DC: 24.3"	"Group enriched"	"Detected in many"	97	"B-cells: 42.0;dendritic cells: 24.3;monocytes: 33.8"	"Cell line enhanced"	"Detected in some"		"Daudi: 6.2;RPMI-8226: 9.1;RPTEC TERT1: 21.9;SK-BR-3: 10.9;U-698: 9.4"	"Region enriched"	"Detected in single"	4	"thalamus: 1.1"	"Low region specificity"	"Detected in many"			"HPA031115, HPA056942"	Enhanced					NA	NA			"Cluster 23: Antigen presenting cells - Antigen presentation"	"Cluster 85: Liver - Metabolism"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 57: B-cells - Immune response"			"HPA031115: AB_10601924, HPA056942: AB_2683281"	"unprognostic (4.27e-2)"	"unprognostic (3.35e-2)"	"unprognostic (3.95e-2)"	"unprognostic (7.48e-3)"	"unprognostic (8.37e-3)"	"unprognostic (2.63e-1)"	"unprognostic (9.79e-2)"	"unprognostic (3.65e-1)"	"unprognostic (2.42e-1)"	"unprognostic (4.75e-3)"	"unprognostic (8.07e-2)"	"unprognostic (1.47e-1)"	"prognostic unfavorable (6.49e-8)"	"unprognostic (1.60e-2)"	"unprognostic (3.65e-2)"	"unprognostic (3.36e-2)"	"unprognostic (6.81e-2)"	1.4	0.8	0.1	5.1	0.2	1.4	5.3	0.1	1.0	0.6	0.5	0.9	0.6	5.4	0.2	0.2	0.2	1.6	0.4	0.3	0.0	31.5	91.7	5.0	8.8	0.0	0.0	0.2	0.1	0.1	0.2	6.8	0.1	0.3	1.1	0.2	0.3	0.2	0.1	0.2	1.2	0.7	0.0	8.4	1.2	1.3	0.8	1.6	0.2	0.0	11.2	5.6	0.1	0.3	0.2	1.8	0.1	0.0	0.0	0.3	0.3	0.1	0.1	0.2	0.4	0.0	0.2	6.2	0.4	0.0	0.2	2.5	0.0	0.2	0.0	1.1	0.0	0.0	0.1	0.1	0.0	0.6	0.2	0.2	0.7	0.1	0.2	0.5	0.0	0.4	0.1	0.9	0.0	0.2	0.0	2.4	1.0	0.9	0.4	1.6	0.1	9.1	21.9	4.5	0.3	0.1	0.0	10.9	0.1	2.1	4.3	2.1	0.0	0.0	0.1	0.1	1.6	0.4	0.6	9.4	0.2	2.7	1.8	0.1	11.0	0.2	0.0	32.3	0.0	36.1	0.0	0.0	11.3	42.0	0.0	0.1	0.3	0.0	33.8	24.3	0.0	6.1	0.1	0.2	0.1	1.0	0.3	0.0	0.0	0.0	0.1	0.0	0.8	0.3	0.1	0.0	0.5	0.0	33.8	1.0	0.1	13.3	2.2	0.0	1.8	0.8	0.4	2.8	11.1	0.0	0.0	3.6	5.5	0.1	5.9	4.8	4.9	9.5	1.5	0.3	0.0	5.2	6.6	0.2	2.3	0.4	2.0	26.6	0.0	0.1	0.7	46.9	7.0	0.0	30.0	0.0	4.1	22.7	49.4	1.8	0.0	33.0	0.0	0.0	5.5	0.0	1.0	1.0	0.6	1.5	0.0	0.0	11.7	0.2	0.2	63.2	2.3	0.0	0.0	0.1	1.3	1.6	0.3	3.1	1.4	180.1	1.6	0.1	0.0	0.1
L2HGDH	"C14orf160, FLJ12618"	ENSG00000087299	"L-2-hydroxyglutarate dehydrogenase"	Q9H9P8	14	50237563-50312229	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cone photoreceptor cells: 56.3;Excitatory neurons: 60.5;Inhibitory neurons: 61.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"basophil: 8.6"	"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA065409, HPA069708"	Approved		Enhanced	Mitochondria		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 36: HEL - Hemostasis"	"Cluster 9: Photoreceptor cells - Phototransduction"	Mitochondria		"HPA065409: AB_2685485, HPA069708: AB_2686179"	"unprognostic (1.74e-1)"	"unprognostic (1.15e-2)"	"unprognostic (1.13e-2)"	"unprognostic (1.23e-3)"	"unprognostic (1.04e-2)"	"unprognostic (4.33e-2)"	"unprognostic (8.84e-2)"	"unprognostic (1.58e-2)"	"unprognostic (4.17e-2)"	"unprognostic (9.91e-2)"	"unprognostic (2.84e-1)"	"unprognostic (1.97e-1)"	"prognostic favorable (9.75e-10)"	"unprognostic (1.24e-2)"	"unprognostic (5.88e-2)"	"unprognostic (1.45e-1)"	"unprognostic (1.02e-2)"	4.6	2.5	2.9	2.2	2.9	2.7	3.7	6.1	5.5	2.3	1.3	4.3	4.7	2.4	3.0	5.1	3.1	2.0	5.2	2.7	2.5	19.6	12.6	1.8	2.6	1.2	2.4	2.5	3.9	6.1	2.3	1.7	1.1	3.3	5.0	11.4	2.8	3.2	15.5	5.1	3.6	2.5	1.2	1.3	4.3	3.9	2.4	3.0	4.8	14.7	3.4	2.4	2.3	4.1	24.3	16.6	6.8	6.6	3.3	2.2	19.1	7.9	4.4	12.2	14.3	26.8	10.8	19.0	9.0	3.2	9.7	17.4	20.6	8.2	13.5	15.2	11.9	41.1	10.9	3.7	3.1	14.7	13.7	2.0	5.2	8.1	7.0	3.1	5.3	19.3	14.7	11.6	3.2	29.0	16.7	6.7	9.9	20.6	17.6	15.6	22.0	14.8	11.4	28.0	13.8	9.9	23.3	17.5	10.4	9.0	22.9	4.0	5.0	7.7	21.5	9.0	10.6	10.5	25.6	26.3	4.3	7.3	8.8	8.6	0.4	0.9	0.9	0.1	2.2	0.8	1.1	1.0	0.6	0.6	1.3	1.7	0.5	1.7	0.1	1.0	1.6	0.5	2.9	2.9	6.1	5.5	2.7	2.5	1.2	2.4	1.1	1.2	2.4	4.1	1.9	41.7	19.2	16.6	5.1	3.7	2.7	2.1	8.6	15.5	3.9	2.2	14.7	2.8	20.4	12.9	56.3	6.4	6.1	4.8	15.6	3.8	35.1	5.2	2.8	4.6	7.8	7.4	60.5	4.2	6.6	5.3	7.7	5.6	18.9	6.0	2.9	14.2	2.1	11.8	61.4	4.3	0.0	2.7	0.6	8.8	2.5	3.3	1.8	13.1	2.4	6.1	7.2	20.6	18.9	2.5	3.6	4.5	3.3	2.7	6.0	21.7	18.4	40.3	0.0	5.8	3.9	14.3	12.6	10.5	6.3	4.9	5.0	4.6	7.6	2.1
LBR	"DHCR14B, TDRD18"	ENSG00000143815	"Lamin B receptor"	Q14739	1	225401502-225428925	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	"DNA-binding, Oxidoreductase, Receptor"	"Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Erythroid cells: 248.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA062236	Enhanced		Supported	"Nuclear membrane"		NA	Yes			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 6: Erythroid cells - Oxygen transport"	"Nuclear membrane"		"HPA062236: AB_2684721"	"unprognostic (2.57e-1)"	"unprognostic (1.57e-1)"	"unprognostic (2.14e-3)"	"unprognostic (1.32e-2)"	"unprognostic (7.96e-2)"	"unprognostic (1.98e-1)"	"prognostic unfavorable (7.30e-4)"	"unprognostic (3.60e-2)"	"unprognostic (1.11e-2)"	"unprognostic (3.43e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.99e-1)"	"unprognostic (6.42e-2)"	"unprognostic (2.08e-1)"	"unprognostic (5.45e-1)"	"unprognostic (8.32e-2)"	"unprognostic (2.78e-1)"	28.6	9.1	8.8	53.2	9.7	95.7	17.1	9.3	11.9	27.3	9.2	61.4	40.7	47.0	44.4	29.7	31.8	21.7	10.0	8.5	10.1	19.4	47.3	19.2	81.6	12.0	9.8	19.4	16.9	5.6	6.5	27.6	11.2	23.8	46.2	5.3	11.1	36.7	9.8	13.8	39.9	41.4	10.2	41.5	28.2	20.5	9.5	105.5	11.8	12.8	70.7	32.3	23.0	13.1	122.2	42.0	154.9	69.3	64.8	39.7	77.3	31.2	39.2	65.0	69.0	87.2	207.2	248.4	66.6	32.8	38.6	88.8	114.2	32.9	98.5	142.2	107.1	61.4	40.4	81.5	39.9	274.7	105.5	34.3	21.3	58.9	52.0	33.1	82.9	117.4	189.6	164.6	44.4	16.3	254.9	156.6	140.6	121.8	14.2	164.9	141.4	234.0	75.6	52.7	40.6	53.4	52.7	39.6	26.6	68.2	53.3	181.0	50.5	17.6	91.7	49.3	115.9	56.6	83.0	274.5	24.3	120.5	61.2	83.6	44.3	67.3	43.6	31.6	50.9	39.0	43.5	48.8	38.4	39.5	42.4	52.9	211.4	41.3	25.2	21.5	61.9	69.8	8.8	9.7	9.3	11.9	8.5	10.1	12.0	9.8	11.2	10.2	9.5	13.1	98.1	28.9	36.4	13.4	86.4	27.0	33.4	17.3	21.6	4.5	11.9	11.0	8.5	48.6	34.4	31.3	6.2	40.5	98.3	33.4	5.9	23.6	1.2	31.5	31.0	53.1	27.0	248.9	10.5	19.8	23.9	29.0	29.0	53.9	10.1	24.0	48.5	73.6	44.4	11.8	14.3	43.0	12.2	88.5	18.1	3.4	33.8	71.7	26.6	19.7	56.0	11.6	82.4	37.2	34.1	20.6	24.6	32.4	74.0	32.9	19.3	26.0	26.0	10.4	39.5	13.9	46.6	21.0	26.7	68.4	35.5	11.1	81.3	13.2	73.8	36.7
LDHA		ENSG00000134333	"Lactate dehydrogenase A"	P00338	11	18394560-18408425	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase	"Cancer-related genes, Disease variant, FDA approved drug targets, Glycogen storage disease"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Basal keratinocytes: 2198.1;Basal respiratory cells: 2133.0;Extravillous trophoblasts: 2086.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"CAB015336, CAB069404"	Uncertain		Supported	Vesicles,Cytosol		NA	NA		170000000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 11: RPE1 & U-87MG - Synaptic function"	"Cluster 16: Pancreatic endocrine cells - Mixed function"	Cytosol	Vesicles	"CAB015336: AB_2134947, CAB069404: "	"unprognostic (8.83e-2)"	"prognostic unfavorable (2.78e-5)"	"unprognostic (3.81e-2)"	"unprognostic (1.73e-1)"	"unprognostic (3.43e-3)"	"unprognostic (4.66e-3)"	"prognostic unfavorable (3.26e-8)"	"prognostic unfavorable (2.27e-6)"	"unprognostic (1.08e-1)"	"unprognostic (1.88e-2)"	"prognostic unfavorable (8.09e-6)"	"unprognostic (1.76e-2)"	"prognostic unfavorable (9.69e-9)"	"unprognostic (4.15e-2)"	"unprognostic (1.89e-1)"	"unprognostic (3.07e-1)"	"unprognostic (1.05e-2)"	444.5	358.1	64.3	139.5	68.4	184.6	330.4	54.0	72.1	203.1	58.4	278.5	158.1	151.1	43.8	450.6	189.2	75.5	361.2	68.4	73.7	440.2	729.2	242.0	97.2	73.6	74.9	149.7	171.5	26.6	95.9	113.9	94.9	170.1	117.4	443.8	267.5	81.8	947.5	468.6	296.6	124.2	58.5	185.3	181.1	95.2	67.4	115.3	180.8	500.3	146.5	266.2	314.4	65.9	1261.4	730.9	28.4	415.2	599.8	399.3	400.6	1186.1	1148.5	936.9	1366.4	324.5	196.6	909.3	380.3	1110.8	727.1	979.2	716.1	1715.1	2082.2	331.3	422.6	329.6	629.4	588.5	148.9	811.2	235.8	411.1	760.3	380.3	373.7	1670.8	550.8	292.3	462.8	431.7	1127.7	319.4	674.8	509.3	182.7	413.2	849.4	432.0	298.0	768.0	1546.6	284.5	220.5	279.3	642.7	518.6	230.8	431.4	241.7	192.9	546.9	1228.3	455.3	1094.7	14.3	348.0	545.1	899.4	1767.1	415.0	434.1	98.4	147.1	79.7	93.8	165.0	105.2	70.4	122.1	99.6	202.1	54.4	78.1	81.0	47.1	91.3	169.3	68.0	140.8	237.6	64.3	68.4	54.0	72.1	68.4	73.7	73.6	74.9	94.9	58.5	67.4	65.9	421.7	73.7	201.6	21.5	220.8	2198.1	475.6	2133.0	523.0	464.2	213.6	229.5	241.8	175.8	837.3	309.0	146.0	509.8	427.2	696.1	434.3	1293.9	204.4	180.0	317.4	492.8	45.6	123.2	38.7	1532.3	2086.2	544.4	163.6	485.8	262.9	205.3	205.6	514.4	659.3	514.8	33.5	285.1	649.0	224.4	1155.1	129.6	287.7	373.9	1177.5	20.6	973.4	444.2	170.0	9.5	12.6	1771.4	590.3	205.0	376.0	546.8	1765.0	682.5	178.1	481.4	190.7	251.6	706.3	195.5	44.0	422.9	1723.2	501.7	410.9	196.2	362.1	530.8
LDHAL6A	"LDH6A, MGC23940"	ENSG00000166800	"Lactate dehydrogenase A like 6A"	Q6ZMR3	11	18455824-18479601	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	6	"testis: 9.8"	"Cell type enhanced"	"Detected in some"		"Early spermatids: 13.3;Excitatory neurons: 3.5;Late spermatids: 7.4;Spermatocytes: 19.3;Spermatogonia: 3.5"	"Not detected"	"Not detected"			"Region enhanced"	"Detected in single"		"cerebellum: 1.6"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	7	"HL-60: 11.0"															NA	NA			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 78: Testis - Spermatogenesis"	"Cluster 32: U-937 - Innate immune response"	"Cluster 66: Spermatocytes - Spermatogenesis"				"unprognostic (1.41e-1)"	"unprognostic (4.84e-2)"	"unprognostic (8.95e-2)"	"unprognostic (5.35e-2)"	"unprognostic (1.03e-1)"	"unprognostic (3.31e-2)"	"unprognostic (7.34e-2)"	"unprognostic (1.75e-1)"	"unprognostic (1.23e-1)"	"unprognostic (1.60e-1)"	"unprognostic (2.35e-2)"	"unprognostic (3.58e-1)"	"unprognostic (2.22e-2)"	"unprognostic (2.51e-1)"	"unprognostic (1.81e-1)"	"unprognostic (8.31e-3)"	"unprognostic (1.48e-1)"	0.1	0.5	0.2	0.3	0.3	1.0	0.1	1.6	0.4	0.0	0.0	0.1	0.6	0.2	0.2	0.2	0.1	0.2	0.1	0.2	0.1	0.1	0.0	0.1	0.4	0.2	0.0	0.3	0.3	0.0	0.1	0.2	0.3	0.1	0.1	1.1	0.2	0.2	0.1	0.9	0.5	0.0	0.0	0.3	0.3	9.8	0.1	0.1	0.5	0.0	0.2	0.0	0.0	0.2	0.1	0.3	0.7	0.5	0.0	0.0	0.4	0.3	0.0	0.0	0.0	0.2	0.3	0.6	0.1	0.0	0.1	0.3	0.0	0.2	0.3	0.5	0.5	0.4	0.7	0.3	0.0	11.0	0.5	0.1	0.2	0.0	0.1	0.1	0.0	0.7	0.3	0.7	0.0	0.2	0.3	0.8	0.2	0.1	0.4	0.5	0.3	0.2	0.1	0.7	0.3	0.3	0.3	0.2	0.1	0.3	0.2	1.5	0.5	0.4	0.1	0.6	0.2	0.2	0.2	0.1	0.2	0.4	0.2	0.6	0.0	0.1	0.4	0.0	0.0	0.2	0.0	0.1	0.1	0.2	0.2	0.2	0.7	0.3	0.1	0.0	0.3	0.1	0.2	0.3	1.6	0.4	0.2	0.1	0.2	0.0	0.3	0.0	0.1	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.8	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.3	0.2	0.0	0.0	0.0	13.3	0.1	0.1	0.1	0.0	0.0	3.5	0.0	0.0	0.1	0.0	0.2	0.0	0.3	0.0	0.0	0.0	0.0	2.5	0.0	0.0	0.0	0.0	7.4	0.9	0.1	0.0	0.0	0.0	0.9	1.0	1.5	0.9	0.0	0.0	0.4	0.0	0.0	0.0	0.3	0.0	0.8	0.0	0.2	0.0	19.3	3.5	0.0	0.0	0.3	0.0	0.3	0.0	0.0
LDHAL6B	"LDH6B, LDHAL6, LDHL"	ENSG00000171989	"Lactate dehydrogenase A like 6B"	Q9BYZ2	15	59206843-59208588	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	17	"testis: 40.6"	"Cell type enriched"	"Detected in some"	13	"Spermatocytes: 101.4"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"HeLa: 1.1"	"Region enriched"	"Detected in single"	6	"olfactory bulb: 1.3"					HPA053962	Enhanced					NA	NA				"Cluster 78: Testis - Spermatogenesis"	"Cluster 20: HeLa - Mitochondria"	"Cluster 66: Spermatocytes - Spermatogenesis"			"HPA053962: AB_2682324"	"unprognostic (1.59e-1)"	"unprognostic (9.41e-2)"	"unprognostic (2.37e-1)"	"unprognostic (4.46e-2)"	"unprognostic (6.59e-2)"	"unprognostic (2.23e-1)"	"unprognostic (1.34e-1)"	"unprognostic (1.58e-1)"	"unprognostic (2.29e-1)"	"unprognostic (1.66e-1)"	"unprognostic (5.13e-3)"	"unprognostic (1.64e-1)"	"unprognostic (3.12e-7)"	"unprognostic (3.47e-2)"	"unprognostic (1.49e-2)"	"unprognostic (8.53e-2)"	"unprognostic (7.80e-2)"	0.3	0.0	0.2	0.2	0.9	0.0	0.2	0.5	0.9	0.2	2.3	0.2	0.1	0.1	0.0	0.1	0.0	0.2	0.1	0.3	0.7	0.2	0.3	0.1	0.1	1.1	0.6	0.0	0.1	0.0	0.0	0.0	1.2	0.2	0.0	0.0	0.1	0.0	0.1	0.3	0.3	0.0	0.5	0.0	0.1	40.6	1.0	0.0	0.1	0.0	0.0	0.1	0.2	1.9	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.1	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.9	0.5	0.9	0.3	0.7	1.1	0.6	1.2	0.5	1.0	1.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	7.3	0.2	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	6.0	1.5	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	101.4	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDHB		ENSG00000111716	"Lactate dehydrogenase B"	P07195	12	21635342-21757857	"Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 1947.7;kidney: 1726.6"	"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 2502.3;Cytotrophoblasts: 1693.0;Distal tubular cells: 3306.5;Proximal tubular cells: 3483.9;Syncytiotrophoblasts: 1639.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"RPTEC TERT1: 6021.8"									"CAB004641, HPA019007"	Enhanced		Supported	Cytosol		No	No		560000000	"Cluster 20: T-cells - T-cell receptor"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 39: Non-specific - Basic cellular processes"	Cytosol		"CAB004641: AB_425525, HPA019007: AB_2670008"	"unprognostic (2.93e-1)"	"unprognostic (9.20e-3)"	"unprognostic (6.10e-2)"	"unprognostic (1.11e-1)"	"unprognostic (5.39e-3)"	"unprognostic (1.36e-3)"	"unprognostic (1.61e-2)"	"unprognostic (1.72e-2)"	"unprognostic (5.34e-2)"	"unprognostic (8.40e-2)"	"unprognostic (2.91e-1)"	"unprognostic (6.41e-2)"	"prognostic favorable (2.51e-4)"	"unprognostic (1.31e-1)"	"unprognostic (1.71e-1)"	"unprognostic (2.55e-1)"	"unprognostic (9.32e-2)"	549.9	424.8	509.1	259.2	528.2	352.8	321.1	593.7	617.0	238.6	549.8	320.2	84.4	273.1	169.0	166.6	252.9	232.9	1947.7	484.1	581.9	1726.6	70.5	220.4	425.8	564.4	575.4	472.4	370.3	447.3	161.3	298.2	556.2	240.9	277.0	290.0	162.3	287.2	309.4	81.4	171.3	309.7	537.8	182.0	459.1	119.5	582.5	534.5	348.5	950.4	449.4	417.9	171.2	517.8	647.2	1697.3	1457.5	966.0	1021.7	1126.6	1689.4	879.8	873.0	1201.5	1179.4	2712.9	3.6	2268.6	561.5	597.3	1170.1	315.8	2031.4	1631.4	1518.4	586.5	1413.1	2339.5	1619.0	3.0	975.0	2212.8	967.9	1300.5	572.1	1056.8	1423.4	1416.9	1395.2	1610.8	1304.6	332.6	1342.7	3.2	1895.9	2665.6	4216.4	1051.1	727.7	1681.3	2032.0	1838.7	6021.8	2832.7	467.2	1077.8	403.6	618.1	1586.1	3842.2	5.3	1704.6	548.3	803.7	1048.1	578.5	1684.5	291.0	420.9	2953.4	891.8	1037.5	978.2	540.8	201.9	25.1	346.8	124.7	583.1	349.4	1341.5	723.8	367.2	250.9	1722.4	1124.1	31.7	459.0	95.2	427.7	1405.8	1431.2	509.1	528.2	593.7	617.0	484.1	581.9	564.4	575.4	556.2	537.8	582.5	517.8	89.8	141.1	316.4	68.2	242.2	73.0	439.5	1103.1	221.4	151.5	332.4	325.0	2502.3	298.8	433.9	474.5	68.8	1693.0	208.0	69.6	3306.5	18.4	10.5	224.3	325.0	227.3	92.4	361.2	39.4	314.9	870.1	299.4	222.8	309.4	268.6	412.6	155.7	11.2	612.9	141.3	55.6	152.2	956.2	189.8	104.3	34.3	274.6	174.8	179.7	33.7	197.3	277.6	159.6	47.7	40.3	99.7	84.3	415.2	303.1	310.6	0.2	3483.9	363.0	118.1	236.7	195.2	363.7	21.5	124.3	216.3	64.2	1639.5	398.1	1105.3	257.0	344.9
LDHC	CT32	ENSG00000166796	"Lactate dehydrogenase C"	P07864	11	18412318-18452063	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	177	"testis: 265.2"	"Group enriched"	"Detected in many"	7	"Early spermatids: 1441.7;Spermatocytes: 1584.7"	"Low cancer specificity"	"Detected in some"			"Low region specificity"	"Detected in single"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in some"		"SK-BR-3: 2.1;U-2197: 5.1;U-266/70: 4.5;U-266/84: 4.2"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in some"			HPA045442	Enhanced					NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 36: Testis - Spermatogenesis"	"Cluster 29: U-266 - Adaptive immune response"	"Cluster 66: Spermatocytes - Spermatogenesis"			"HPA045442: AB_10966720"	"unprognostic (2.32e-2)"	"unprognostic (3.42e-3)"	"unprognostic (1.87e-1)"	"unprognostic (2.83e-2)"	"unprognostic (2.19e-1)"	"unprognostic (8.56e-4)"	"unprognostic (1.35e-1)"	"unprognostic (5.74e-2)"	"unprognostic (6.65e-2)"	"unprognostic (1.73e-1)"	"unprognostic (2.04e-1)"	"unprognostic (1.18e-2)"	"unprognostic (1.08e-1)"	"unprognostic (9.30e-2)"	"unprognostic (3.00e-1)"	"unprognostic (4.25e-1)"	"unprognostic (1.93e-1)"	0.1	0.2	0.6	0.0	0.6	0.4	0.4	1.2	0.9	0.1	0.4	0.3	0.3	0.0	0.6	0.3	0.6	0.0	0.3	0.7	0.3	0.6	1.4	0.2	0.4	0.3	0.3	0.4	1.4	0.0	0.2	0.1	0.4	0.3	0.0	0.6	0.5	0.0	0.7	0.4	0.7	0.1	0.1	0.1	0.1	265.2	0.5	0.3	0.6	0.2	0.7	0.2	0.0	0.4	0.0	0.0	0.1	1.2	0.9	0.9	1.2	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	1.6	0.1	0.7	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.1	0.6	0.1	0.1	0.3	0.0	0.2	0.1	0.2	0.0	0.1	0.3	0.0	0.0	0.0	0.0	0.0	1.1	0.0	1.3	2.1	0.3	0.0	0.1	0.0	0.5	0.2	1.6	5.1	0.0	4.5	4.2	0.2	0.1	0.0	0.0	0.6	0.2	0.3	0.1	0.3	0.6	0.2	0.5	0.6	0.0	0.7	1.0	0.7	1.1	0.0	0.3	0.9	0.6	0.3	0.6	0.6	1.2	0.9	0.7	0.3	0.3	0.3	0.4	0.1	0.5	0.4	1.9	0.0	0.0	1.3	1.3	0.1	0.8	0.4	1.2	0.1	2.5	3.2	0.9	0.0	1.0	1.8	0.0	0.0	0.1	0.4	3.9	1.6	1441.7	3.7	0.8	2.0	0.0	0.4	1.0	6.3	0.1	1.3	0.5	1.9	0.0	0.3	0.4	0.2	0.2	0.0	0.9	0.2	0.0	0.0	0.4	209.5	23.3	2.7	0.0	1.9	0.0	1.5	0.0	1.0	2.0	2.0	0.0	18.0	0.9	0.3	0.0	3.5	1.2	0.6	19.7	1.2	1.2	1584.7	30.7	1.0	0.6	0.0	1.4	0.1	0.0	0.3
LDHD		ENSG00000166816	"Lactate dehydrogenase D"	Q86WU2	16	75111860-75116780	"Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 85.6;liver: 135.5"	"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 37.3;Distal enterocytes: 80.2;Distal tubular cells: 37.2;Hepatocytes: 88.6;Proximal tubular cells: 118.1"	"Cancer enhanced"	"Detected in all"		"liver cancer: 32.7"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"basophil: 11.1"	"Group enriched"	"Detected in many"	45	"granulocytes: 11.1;monocytes: 4.8"	"Cell line enhanced"	"Detected in many"		"Hep G2: 11.4;HMC-1: 14.4;T-47d: 29.1;U-266/70: 11.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041766, HPA048639, HPA066148"	Enhanced		Approved	Cytosol		No	NA			"Cluster 34: Basophils - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 6: T47d - Mammary gland"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Cytosol		"HPA041766: AB_2677660, HPA048639: AB_2680473, HPA066148: AB_2685626"	"unprognostic (8.75e-2)"	"unprognostic (3.68e-3)"	"unprognostic (1.27e-1)"	"unprognostic (5.28e-2)"	"unprognostic (1.57e-1)"	"unprognostic (1.53e-1)"	"prognostic favorable (5.61e-4)"	"unprognostic (2.49e-3)"	"unprognostic (1.91e-1)"	"unprognostic (2.72e-1)"	"unprognostic (3.74e-1)"	"unprognostic (4.01e-1)"	"prognostic favorable (2.95e-14)"	"unprognostic (4.10e-3)"	"unprognostic (4.49e-2)"	"unprognostic (7.00e-2)"	"unprognostic (2.20e-1)"	24.9	14.4	17.7	2.1	19.7	0.7	11.7	20.5	22.6	5.4	34.1	27.2	8.8	3.5	1.1	10.8	5.5	3.0	85.6	16.1	18.9	36.1	135.5	4.9	0.8	20.8	20.2	16.4	18.7	17.0	11.8	0.7	22.4	8.1	9.7	1.3	21.3	3.2	68.7	5.8	5.7	1.2	17.0	1.1	23.1	1.7	19.3	0.5	10.6	52.7	0.6	2.6	3.7	17.5	0.7	2.1	0.0	0.2	1.6	1.4	6.1	0.2	0.1	0.2	0.2	2.8	2.6	0.1	2.1	0.9	1.0	0.3	0.0	0.1	0.0	0.0	0.2	0.1	0.8	11.4	2.6	0.0	14.4	2.0	0.3	0.0	0.0	0.6	0.1	0.4	0.7	2.5	0.0	5.3	0.1	0.8	1.4	2.7	1.3	0.0	0.0	7.8	1.4	0.1	0.0	0.0	0.2	5.2	0.3	0.7	29.1	3.3	0.0	0.0	0.2	0.0	0.0	11.5	0.6	0.0	1.9	0.1	0.0	11.1	2.2	0.6	0.0	3.6	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	4.8	0.0	0.0	0.8	17.7	19.7	20.5	22.6	16.1	18.9	20.8	20.2	22.4	17.0	19.3	17.5	1.6	0.0	6.7	7.8	1.0	0.6	1.8	2.2	0.6	0.5	6.5	2.4	37.3	11.5	2.3	11.0	0.0	2.1	0.1	80.2	37.2	2.3	0.4	2.2	0.3	1.7	3.0	2.7	1.0	6.2	1.2	2.3	32.6	3.8	10.2	2.1	4.2	88.6	7.2	1.7	1.4	11.0	0.0	6.0	1.0	0.6	0.0	3.0	5.4	1.9	2.0	12.0	0.0	1.0	3.2	3.0	28.3	0.0	0.8	2.1	2.4	118.1	2.0	1.4	0.0	4.1	1.3	0.0	0.7	3.6	0.3	3.1	1.0	1.8	15.7	1.5
LOX		ENSG00000113083	"Lysyl oxidase"	P28300	5	122063195-122078413	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins"		Oxidoreductase	"Aortic aneurysm, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 27.9"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 67.1;Club cells: 38.4;Early spermatids: 41.9;Endometrial stromal cells: 34.0;Extravillous trophoblasts: 44.2;Fibroblasts: 79.1;Peritubular cells: 39.1;Smooth muscle cells: 32.7"	"Cancer enhanced"	"Detected in all"		"renal cancer: 39.8"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BJ: 777.3;fHDF/TERT166: 1790.7;HSkMC: 356.3;U-138 MG: 475.5"	"Low region specificity"	"Detected in some"			"Low region specificity"	"Detected in many"			HPA043930			Approved	"Endoplasmic reticulum"	"Secreted to extracellular matrix"	NA	NA		550000		"Cluster 82: Adipose tissue - ECM organization"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 33: Fibroblasts - ECM organization"	"Endoplasmic reticulum"		"HPA043930: AB_2678736"	"unprognostic (5.10e-2)"	"unprognostic (1.03e-2)"	"unprognostic (6.99e-3)"	"unprognostic (3.64e-2)"	"unprognostic (9.86e-3)"	"unprognostic (1.91e-1)"	"prognostic unfavorable (7.38e-4)"	"unprognostic (2.42e-3)"	"unprognostic (3.06e-3)"	"unprognostic (8.92e-2)"	"unprognostic (3.21e-3)"	"unprognostic (1.91e-1)"	"prognostic unfavorable (3.93e-8)"	"unprognostic (1.11e-3)"	"unprognostic (9.92e-2)"	"unprognostic (4.31e-2)"	"prognostic unfavorable (3.32e-4)"	27.9	2.4	0.4	6.8	0.4	0.2	17.6	0.5	0.9	10.8	0.8	4.2	3.8	6.2	1.7	5.6	8.9	18.8	23.9	0.3	0.4	4.5	2.1	13.6	3.3	1.3	1.4	5.4	3.3	0.9	1.2	8.1	0.8	4.1	4.5	1.1	3.2	2.6	1.9	12.4	3.7	10.0	1.2	2.6	4.4	1.4	0.5	0.9	6.9	2.1	1.4	14.1	4.8	1.0	0.8	0.2	2.0	0.9	168.7	185.2	0.1	777.3	205.3	73.2	246.4	0.5	0.3	0.1	16.5	1790.7	3.7	0.2	4.5	3.5	196.4	0.1	2.0	0.0	16.3	9.3	203.4	0.4	0.1	356.3	4.4	137.6	7.4	329.3	95.3	0.1	0.0	0.1	83.6	0.0	0.1	0.3	6.4	0.1	1.9	0.1	7.4	0.9	4.9	0.5	0.5	4.2	72.1	0.1	12.9	29.8	0.6	0.6	6.8	475.5	23.2	272.8	9.3	0.0	0.1	0.2	207.1	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.4	0.5	0.9	0.3	0.4	1.3	1.4	0.8	1.2	0.5	1.0	20.0	9.6	1.1	0.0	0.2	7.8	1.9	67.1	0.0	0.6	1.3	1.1	2.1	0.0	38.4	0.0	0.0	0.8	0.1	0.0	0.0	7.2	41.9	8.4	34.0	9.4	0.0	0.0	0.3	0.6	44.2	79.1	0.0	6.6	0.0	0.1	10.8	0.5	2.2	1.7	2.0	0.0	2.0	0.8	21.6	5.0	14.0	1.3	5.4	1.9	0.6	0.0	0.0	0.0	0.0	1.3	0.0	39.1	0.3	2.8	0.0	0.1	8.3	1.7	19.7	1.1	32.7	0.8	0.6	1.8	10.7	4.8	1.1	0.4	0.1	0.9
LOXL2	"LOR, WS9-14"	ENSG00000134013	"Lysyl oxidase like 2"	Q9Y4K0	8	23296897-23425328	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Oxidoreductase, Repressor"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"smooth muscle: 41.3"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 26.9;Endometrial stromal cells: 26.9;Endothelial cells: 33.1;Extravillous trophoblasts: 22.0;Fibroblasts: 22.9;Hepatic stellate cells: 19.6;Sertoli cells: 26.3;Smooth muscle cells: 48.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BJ: 935.5;BJ hTERT+ SV40 Large T+ RasG12V: 517.3;fHDF/TERT166: 602.7;TIME: 510.7;U-87 MG: 905.4"	"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in single"			"CAB025848, HPA036257, HPA056542"	Approved		Enhanced	Nucleoplasm	"Secreted to extracellular matrix"	NA	NA			"Cluster 49: Eosinophils - Unknown function"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 33: Fibroblasts - ECM organization"	Nucleoplasm		"CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168"	"unprognostic (9.48e-2)"	"prognostic unfavorable (9.83e-6)"	"unprognostic (2.03e-1)"	"unprognostic (2.81e-2)"	"prognostic unfavorable (1.24e-4)"	"unprognostic (5.55e-2)"	"unprognostic (1.42e-2)"	"prognostic unfavorable (1.46e-7)"	"unprognostic (2.91e-2)"	"unprognostic (3.63e-3)"	"prognostic unfavorable (9.05e-4)"	"unprognostic (1.25e-1)"	"prognostic unfavorable (2.91e-7)"	"unprognostic (1.51e-2)"	"unprognostic (7.07e-2)"	"unprognostic (4.93e-2)"	"unprognostic (3.68e-3)"	30.4	3.3	1.9	15.9	2.7	1.2	18.8	4.7	3.0	10.6	0.8	25.3	9.3	12.0	0.9	3.8	4.9	8.0	10.7	1.8	3.2	6.1	3.9	8.3	11.7	7.7	8.1	12.9	6.5	2.5	2.6	36.2	7.0	7.5	5.4	3.0	4.1	13.0	4.5	5.4	10.3	41.3	4.5	5.0	9.0	2.3	4.5	1.8	5.2	2.6	9.5	12.0	7.3	3.7	58.2	147.7	42.7	35.8	112.4	183.8	19.4	935.5	295.9	415.6	517.3	1.1	4.4	10.7	7.5	602.7	193.2	47.6	2.1	79.0	215.3	1.8	8.5	0.9	19.4	1.0	226.8	0.5	3.8	164.6	3.9	155.0	20.8	274.0	350.7	2.4	0.5	2.0	138.1	32.3	0.6	1.4	29.1	0.4	24.5	1.9	36.7	0.4	120.1	0.3	0.9	13.7	122.9	6.1	8.6	131.3	0.8	1.2	510.7	384.6	103.3	163.8	127.3	4.1	0.8	29.9	905.4	1.4	413.5	0.1	0.2	0.8	0.4	0.1	0.2	0.4	0.1	0.3	0.1	0.1	0.2	0.6	0.3	0.1	0.2	0.2	0.1	0.2	1.9	2.7	4.7	3.0	1.8	3.2	7.7	8.1	7.0	4.5	4.5	3.7	12.9	0.0	3.0	6.8	0.6	2.5	0.3	26.9	0.6	1.5	0.6	9.7	2.6	1.5	4.1	0.0	0.0	2.7	0.4	0.0	0.0	1.9	0.6	1.7	26.9	33.1	0.0	0.0	8.1	1.5	22.0	22.9	1.5	2.1	0.0	2.0	19.6	0.2	1.3	1.7	3.2	0.1	0.0	0.3	5.7	0.4	0.9	0.9	3.6	6.5	0.0	1.2	0.0	7.1	11.9	2.3	0.1	0.4	0.9	0.6	0.2	0.2	1.6	3.2	26.3	2.7	48.1	1.3	1.6	0.5	3.1	1.0	1.0	3.1	0.4	0.2
LOXL3		ENSG00000115318	"Lysyl oxidase like 3"	P58215	2	74532258-74555690	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins"	"Inflammatory response"	Oxidoreductase	"Deafness, Stickler syndrome"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"Astrocytes: 14.0;Hofbauer cells: 17.9;Kupffer cells: 12.5;Macrophages: 12.3;Microglial cells: 30.0;Muller glia cells: 10.6;Oligodendrocyte precursor cells: 11.6;Sertoli cells: 19.7"	"Cancer enhanced"	"Detected in many"		"melanoma: 15.4"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"intermediate monocyte: 11.7;non-classical monocyte: 9.3"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 143.4;HDLM-2: 110.7;U-138 MG: 245.9;WM-115: 549.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA035281	Approved				"Secreted to extracellular matrix"	NA	NA		200000	"Cluster 7: Monocytes - Unknown function"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 17: WM-115 - Nervous system development"	"Cluster 33: Fibroblasts - ECM organization"			"HPA035281: AB_10601766"	"unprognostic (7.54e-2)"	"unprognostic (2.53e-2)"	"unprognostic (5.34e-3)"	"unprognostic (4.55e-3)"	"unprognostic (6.85e-2)"	"unprognostic (1.96e-1)"	"unprognostic (1.68e-3)"	"unprognostic (6.84e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.78e-1)"	"unprognostic (1.52e-1)"	"unprognostic (1.09e-1)"	"prognostic unfavorable (7.97e-8)"	"unprognostic (1.22e-2)"	"unprognostic (7.33e-3)"	"unprognostic (7.09e-2)"	"unprognostic (3.38e-2)"	6.8	5.3	4.5	7.8	4.7	14.3	3.0	4.5	5.3	5.1	3.8	7.3	4.0	7.4	1.7	3.2	4.9	6.5	8.2	4.5	5.6	2.0	1.5	4.6	4.1	7.0	5.0	2.9	1.1	1.7	2.7	15.9	6.3	3.3	3.7	4.9	1.6	4.0	1.3	2.0	3.9	8.1	5.6	8.9	2.7	2.6	7.0	1.4	2.2	1.5	2.3	5.2	4.0	7.3	1.6	0.3	21.8	3.7	17.1	20.6	4.5	71.0	143.4	33.8	31.8	25.6	1.3	0.1	0.9	73.1	1.6	1.1	2.8	1.8	19.8	110.7	1.0	17.6	1.8	0.2	5.7	0.6	16.7	22.6	0.2	90.6	3.8	12.0	0.7	0.8	0.8	2.8	6.4	4.1	0.2	6.5	12.0	0.8	0.7	2.0	3.1	0.3	0.3	1.2	11.2	12.8	0.6	1.1	14.7	3.2	2.3	1.3	0.3	245.9	8.2	1.4	0.9	1.4	0.5	0.1	92.5	6.8	549.6	0.1	6.0	0.3	0.0	11.7	0.0	0.1	0.1	0.0	3.5	0.1	0.0	0.0	2.5	0.0	9.3	0.4	0.0	2.6	4.5	4.7	4.5	5.3	4.5	5.6	7.0	5.0	6.3	5.6	7.0	7.3	0.9	0.0	0.5	14.0	0.3	0.9	0.2	0.6	0.6	0.9	0.4	0.8	0.3	1.5	0.0	0.0	0.0	0.7	0.2	0.0	0.0	0.8	0.0	0.2	4.8	1.2	0.0	0.4	0.4	0.0	1.5	7.1	0.0	0.5	1.3	0.7	0.4	0.1	17.9	1.7	4.2	0.1	0.0	12.5	2.5	0.7	5.0	12.3	0.0	30.0	4.8	10.6	1.0	11.6	0.6	0.3	0.0	4.5	0.1	0.3	0.0	0.1	0.0	0.9	19.7	1.6	5.3	0.6	0.8	0.1	0.1	0.8	0.4	0.2	0.0	0.2
LPO	SPO	ENSG00000167419	Lactoperoxidase	P22079	17	58218548-58268518	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins"	"Hydrogen peroxide"	"Antimicrobial, Oxidoreductase, Peroxidase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	404	"salivary gland: 1026.8"	"Group enriched"	"Detected in some"	6	"Breast glandular cells: 25.2;Early spermatids: 8.3;Late spermatids: 14.1"	"Not detected"	"Not detected"			"Region enriched"	"Detected in single"	4	"midbrain: 2.5"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in single"	10	"THP-1: 9.9"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			HPA028688	Enhanced	Supported			"Secreted to digestive system"	NA	NA				"Cluster 24: Salivary gland - Salivary secretion"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 30: Mammary glandular cells - Lactation"			"HPA028688: AB_10601909"	"unprognostic (2.74e-1)"	"unprognostic (5.12e-2)"	"unprognostic (4.14e-3)"	"unprognostic (1.56e-3)"	"unprognostic (2.41e-2)"	"unprognostic (9.71e-2)"	"unprognostic (2.06e-2)"	"unprognostic (1.53e-1)"	"unprognostic (2.40e-2)"	"unprognostic (6.27e-3)"	"unprognostic (6.32e-2)"	"unprognostic (2.56e-1)"	"unprognostic (0.00e+0)"	"unprognostic (3.41e-2)"	"unprognostic (3.15e-1)"	"unprognostic (2.72e-2)"	"unprognostic (1.22e-1)"	0.0	0.0	0.1	0.0	0.0	0.6	0.0	0.1	0.1	0.4	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.1	0.1	0.3	0.0	0.0	0.0	0.0	0.0	2.5	0.0	1.2	0.0	0.0	0.1	0.0	0.0	0.0	0.1	1026.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.4	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	9.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.1	0.1	0.3	0.0	2.5	0.0	0.0	0.5	0.1	0.2	0.0	0.0	0.0	0.0	0.3	0.7	0.0	0.0	0.7	25.2	0.5	0.7	0.0	0.6	0.0	0.0	0.0	0.3	0.0	0.0	0.1	8.3	0.3	0.1	0.3	0.0	0.0	0.6	0.0	0.0	0.2	0.0	0.1	1.3	0.0	0.4	0.0	0.2	1.7	0.3	0.0	0.0	0.0	0.0	14.1	0.3	0.1	0.0	0.0	0.6	0.0	0.0	0.0	0.1	0.3	0.0	0.4	0.0	0.5	1.4	0.1	0.0	0.3	0.0	0.2	0.1	2.6	0.4	0.0	0.3	0.0	0.2	0.0	0.5	0.5
MAOA		ENSG00000189221	"Monoamine oxidase A"	P21397	X	43654907-43746824	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins"	"Catecholamine metabolism, Neurotransmitter degradation"	Oxidoreductase	"Disease variant, FDA approved drug targets, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 230.3"	"Cell type enhanced"	"Detected in many"		"Proximal enterocytes: 819.8;Proximal tubular cells: 569.9;Undifferentiated cells: 285.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"ASC diff: 162.1;HHSteC: 302.9;HSkMC: 76.1;hTCEpi: 87.2;RT4: 131.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009437, HPA054807, HPA059299"	Enhanced		Supported	Mitochondria,Cytosol		No	No				"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Mitochondria	Cytosol	"CAB009437: AB_2137260, HPA054807: AB_2682607, HPA059299: AB_2683970"	"unprognostic (9.54e-3)"	"unprognostic (1.63e-1)"	"unprognostic (7.99e-2)"	"unprognostic (3.07e-1)"	"unprognostic (6.75e-2)"	"unprognostic (3.32e-1)"	"unprognostic (9.51e-2)"	"unprognostic (6.89e-3)"	"unprognostic (2.21e-1)"	"unprognostic (4.29e-2)"	"unprognostic (3.94e-1)"	"unprognostic (3.54e-1)"	"unprognostic (1.45e-3)"	"unprognostic (1.16e-2)"	"unprognostic (1.47e-1)"	"unprognostic (4.04e-2)"	"unprognostic (2.98e-3)"	143.9	27.7	24.7	8.6	27.6	0.4	71.6	26.5	26.6	26.6	13.9	116.4	163.4	24.0	14.1	46.7	39.1	16.9	49.6	22.3	31.7	76.9	119.1	63.5	2.4	26.9	32.5	40.7	39.1	31.4	4.0	30.2	56.4	46.3	117.9	28.2	77.3	35.0	33.5	37.4	230.3	24.0	21.3	6.3	55.9	3.7	41.4	9.9	118.4	34.3	5.3	65.0	38.8	19.0	0.0	3.7	0.6	9.9	162.1	0.0	0.6	0.2	0.0	0.0	0.0	0.4	0.4	0.0	0.2	0.0	4.6	17.2	6.1	22.3	0.1	0.0	2.5	6.9	0.5	18.6	302.9	0.0	16.9	76.1	87.2	0.2	45.2	0.1	20.0	0.0	0.3	0.4	5.7	2.9	0.1	0.8	1.6	20.7	5.0	0.0	0.3	0.5	22.3	131.8	3.1	7.8	0.0	0.0	0.3	0.4	0.5	0.0	8.7	0.0	8.2	0.7	0.0	0.3	0.0	0.0	9.5	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	24.7	27.6	26.5	26.6	22.3	31.7	26.9	32.5	56.4	21.3	41.4	19.0	35.2	70.5	146.9	23.2	4.6	11.0	177.7	32.3	116.7	5.0	13.6	10.2	101.3	94.4	49.3	60.7	22.9	11.5	0.2	248.0	121.3	36.7	25.2	50.4	42.5	43.6	38.0	4.8	4.0	13.4	21.3	24.3	40.2	175.1	5.7	7.3	53.6	193.7	6.6	3.3	5.0	137.5	67.1	12.2	2.1	33.9	5.6	6.7	10.6	21.5	17.1	25.4	0.0	7.5	1.3	49.5	140.5	0.0	2.6	64.6	819.8	569.9	32.8	27.4	6.6	4.4	30.5	1.3	0.8	120.6	14.3	207.0	3.7	3.5	285.1	129.0
MAOB		ENSG00000069535	"Monoamine oxidase B"	P27338	X	43766610-43882450	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins"		Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 317.6"	"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 120.6;granulocytes: 137.8;Hepatocytes: 221.1;Peritubular cells: 95.2;Proximal enterocytes: 178.8;Proximal tubular cells: 182.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	7	"Hep G2: 41.4;SiHa: 78.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002328, CAB037200"	Enhanced					NA	NA		110000		"Cluster 15: Liver - Metabolism"	"Cluster 20: HeLa - Mitochondria"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"CAB037200: AB_1841012, HPA002328: AB_1854062"	"unprognostic (1.19e-2)"	"unprognostic (1.36e-1)"	"unprognostic (5.16e-2)"	"unprognostic (1.85e-2)"	"unprognostic (4.39e-2)"	"unprognostic (2.69e-2)"	"unprognostic (5.61e-2)"	"unprognostic (4.37e-2)"	"unprognostic (1.56e-1)"	"unprognostic (1.04e-2)"	"unprognostic (1.20e-1)"	"unprognostic (1.54e-2)"	"unprognostic (9.74e-2)"	"unprognostic (5.35e-3)"	"unprognostic (1.48e-2)"	"unprognostic (3.53e-1)"	"unprognostic (1.90e-3)"	78.0	51.1	99.3	6.5	102.8	0.1	45.7	89.1	117.7	32.3	83.5	46.5	73.5	119.4	55.0	31.4	98.0	17.3	97.8	93.9	149.1	124.2	317.6	33.0	6.1	143.8	134.2	155.4	10.9	15.6	25.9	11.2	125.9	82.9	16.5	13.9	78.5	155.5	114.6	9.9	79.0	103.3	115.8	2.4	23.7	9.0	145.2	3.8	5.6	65.1	7.1	28.3	25.4	115.8	0.0	1.0	0.1	0.0	0.6	0.1	0.3	0.0	0.0	0.0	0.0	5.4	4.7	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.1	8.1	41.4	0.0	0.2	0.0	0.3	0.1	0.1	0.0	0.9	0.0	0.0	0.0	0.0	0.2	0.5	0.0	0.3	3.5	0.0	0.0	0.0	0.0	0.4	4.0	0.0	0.1	1.1	78.2	0.0	0.5	0.6	0.0	0.0	0.0	0.0	3.1	0.1	0.0	0.0	0.0	0.1	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	99.3	102.8	89.1	117.7	93.9	149.1	143.8	134.2	125.9	115.8	145.2	115.8	5.9	0.0	4.1	53.5	0.4	5.5	0.4	1.2	1.8	1.4	3.5	22.4	120.6	52.9	1.9	5.5	4.2	0.4	0.0	10.2	62.6	20.1	0.4	26.4	81.6	10.3	0.0	2.7	36.9	2.8	0.5	17.0	16.3	6.0	137.8	69.6	7.5	221.1	1.5	15.2	7.6	6.4	12.2	4.3	3.6	2.1	46.0	1.8	7.2	9.4	0.0	27.2	0.0	11.6	1.3	7.9	7.8	95.2	0.3	0.6	178.8	182.6	11.8	1.0	13.1	2.6	18.4	0.3	0.4	2.3	4.0	0.4	5.5	0.5	10.5	0.5
MDH1		ENSG00000014641	"Malate dehydrogenase 1"	P40925	2	63588609-63607197	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Disease variant, Epilepsy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 1349.1;tongue: 1843.8"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 1926.9;Proximal tubular cells: 1428.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA027296, CAB047333, HPA054276"	Uncertain		Supported	Centrosome,Cytosol		NA	NA		49000000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 39: Non-specific - Basic cellular processes"	"Centrosome, Cytosol"		"CAB047333: , HPA027296: AB_10611118, HPA054276: AB_2682434"	"unprognostic (1.01e-1)"	"unprognostic (6.52e-3)"	"unprognostic (1.61e-2)"	"prognostic unfavorable (7.13e-4)"	"unprognostic (1.83e-1)"	"unprognostic (8.84e-3)"	"unprognostic (5.81e-2)"	"unprognostic (2.79e-2)"	"unprognostic (9.52e-2)"	"unprognostic (2.05e-1)"	"unprognostic (3.26e-1)"	"unprognostic (8.80e-2)"	"prognostic favorable (9.95e-4)"	"unprognostic (6.37e-2)"	"unprognostic (1.75e-1)"	"unprognostic (5.97e-2)"	"unprognostic (3.05e-1)"	274.6	213.6	235.9	86.7	249.7	79.1	137.9	245.9	353.6	89.6	230.2	167.7	154.7	82.0	161.3	125.3	114.5	87.2	1349.1	253.2	261.5	371.6	266.3	89.8	131.9	248.5	218.3	80.4	69.9	411.8	107.2	92.5	253.3	125.5	190.9	240.7	122.0	142.0	792.5	87.7	133.1	171.5	215.7	71.6	192.6	70.5	259.1	170.4	125.5	1843.8	165.4	131.5	62.8	237.7	268.2	219.5	257.8	173.2	369.6	280.9	282.3	215.1	295.9	300.6	304.1	252.5	215.4	355.2	112.8	264.1	358.8	214.3	303.0	355.0	425.5	207.6	253.1	337.0	173.2	376.8	202.1	384.1	223.9	277.7	241.3	271.5	152.7	236.2	235.3	308.1	183.7	217.3	395.1	157.8	300.6	317.5	158.0	376.3	266.5	235.2	349.7	310.5	460.9	251.0	249.9	153.6	182.5	257.7	384.1	205.6	191.9	341.9	149.6	220.3	211.9	187.1	252.9	264.6	264.8	407.6	266.2	312.2	184.1	271.3	186.3	200.2	202.7	267.8	218.8	258.5	236.6	224.6	241.0	258.5	230.3	221.6	28.1	214.6	253.4	184.3	320.9	321.2	235.9	249.7	245.9	353.6	253.2	261.5	248.5	218.3	253.3	215.7	259.1	237.7	44.4	60.9	54.3	54.9	78.7	81.6	109.4	562.9	50.7	165.4	81.0	86.7	1926.9	95.8	227.2	134.3	70.9	248.7	78.4	128.4	630.0	186.2	12.4	116.1	72.6	61.0	62.8	62.9	120.2	108.1	257.0	134.7	112.7	68.8	80.5	95.0	36.0	153.2	397.0	122.8	130.0	115.9	380.5	85.2	65.8	15.1	100.0	98.4	177.9	43.1	155.0	136.3	73.2	51.3	58.8	91.3	99.8	109.1	82.1	48.8	177.4	1428.3	224.5	164.1	59.2	68.3	167.8	58.0	65.6	82.7	84.0	149.5	84.3	137.4	167.8	102.6
MDH2		ENSG00000146701	"Malate dehydrogenase 2"	P40926	7	76048051-76067508	"Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Tricarboxylic acid cycle"	Oxidoreductase	"Disease variant, Epilepsy, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 697.1;tongue: 601.9"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019714, HPA019716, HPA019848, HPA026720"	Enhanced		Enhanced	Mitochondria		No	No		14000000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria		"HPA019714: AB_1853678, HPA019716: AB_1853680, HPA019848: AB_1853683, HPA026720: AB_1853685"	"unprognostic (3.20e-2)"	"unprognostic (2.85e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.43e-2)"	"unprognostic (5.55e-3)"	"unprognostic (8.94e-2)"	"unprognostic (6.45e-2)"	"unprognostic (3.77e-2)"	"unprognostic (3.60e-1)"	"unprognostic (2.02e-2)"	"unprognostic (1.40e-1)"	"unprognostic (9.70e-2)"	"prognostic favorable (1.49e-5)"	"unprognostic (8.57e-2)"	"unprognostic (9.64e-2)"	"unprognostic (5.68e-2)"	"unprognostic (2.66e-1)"	76.9	163.4	68.0	51.4	73.6	71.9	73.9	62.1	83.9	67.4	81.3	118.7	112.7	69.2	34.7	144.9	66.8	38.0	367.5	73.5	69.9	121.7	215.5	60.7	62.4	66.7	61.4	64.1	118.3	90.5	70.7	45.2	67.0	67.3	80.3	40.2	98.8	56.8	697.1	119.5	94.4	60.0	56.3	75.6	103.2	60.2	64.1	60.4	62.3	601.9	66.2	85.6	82.4	66.6	176.5	278.4	99.2	250.7	110.3	121.2	172.0	113.9	145.8	159.4	143.2	246.2	204.7	261.3	51.1	151.1	172.6	174.4	256.3	170.0	112.7	192.1	368.3	144.6	138.7	229.9	135.2	229.3	144.6	153.7	149.7	155.2	229.3	124.9	150.9	160.5	466.3	149.4	149.7	389.6	206.4	402.1	222.8	306.6	344.3	164.3	121.7	379.9	149.9	225.5	247.4	226.9	114.6	567.5	247.0	124.9	323.4	260.0	117.7	160.0	151.6	175.5	232.7	166.5	148.1	290.8	138.6	289.1	249.1	95.4	129.9	63.3	102.4	148.8	107.1	122.2	113.7	111.2	176.0	110.2	109.0	102.6	34.0	107.4	164.2	157.2	156.6	175.8	68.0	73.6	62.1	83.9	73.5	69.9	66.7	61.4	67.0	56.3	64.1	66.6	98.8	51.3	65.9	7.8	110.2	135.9	190.8	437.9	118.4	68.0	151.8	165.5	486.2	135.8	217.3	115.8	18.8	328.1	104.9	242.3	448.0	269.8	263.7	108.0	97.9	96.8	169.7	97.2	13.0	333.1	334.0	112.6	111.1	104.8	54.5	150.9	88.5	246.6	248.1	72.3	15.0	280.6	288.9	132.6	113.5	161.5	99.4	117.6	181.5	9.4	171.4	85.7	126.7	8.0	12.8	255.0	252.1	99.3	149.8	197.3	433.3	466.3	139.0	67.3	85.5	114.7	150.9	157.8	65.3	256.6	166.1	294.8	105.4	233.4	372.7	234.7
ME1		ENSG00000065833	"Malic enzyme 1"	P48163	6	83210402-83431051	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 71.8;Excitatory neurons: 117.1;Inhibitory neurons: 70.6;Kupffer cells: 74.4;Muller glia cells: 100.6;Oligodendrocyte precursor cells: 123.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in some"	7	"MAIT T-cell: 16.0"	"Lineage enriched"	"Detected in many"	10	"T-cells: 16.0"	"Cell line enhanced"	"Detected in many"		"CACO-2: 139.4;OE19: 158.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA006493	Enhanced		Uncertain	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA		3600000	"Cluster 16: MAIT-cells - Unknown function"	"Cluster 54: Non-specific - Microtubule organization"	"Cluster 21: OE19 - Mitochondria"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	"Nucleoplasm, Plasma membrane"	Cytosol	"HPA006493: AB_1078272"	"unprognostic (7.21e-2)"	"unprognostic (3.99e-2)"	"unprognostic (2.24e-1)"	"unprognostic (3.12e-3)"	"prognostic unfavorable (7.73e-4)"	"unprognostic (7.98e-3)"	"prognostic unfavorable (4.57e-5)"	"unprognostic (3.24e-1)"	"unprognostic (4.44e-3)"	"unprognostic (1.41e-3)"	"unprognostic (7.10e-3)"	"unprognostic (2.43e-1)"	"prognostic unfavorable (1.81e-7)"	"unprognostic (4.07e-2)"	"unprognostic (2.49e-1)"	"unprognostic (1.85e-2)"	"unprognostic (4.51e-2)"	41.4	44.4	13.4	5.2	15.4	0.4	29.9	14.5	18.1	8.0	8.5	7.7	21.7	4.2	6.5	28.6	4.2	15.5	18.6	13.1	17.4	3.6	9.8	8.8	4.2	15.0	19.1	10.8	3.4	19.9	12.5	2.9	18.3	8.4	11.0	30.0	10.3	17.2	34.7	14.4	10.4	7.8	13.4	7.3	23.8	16.1	16.8	5.6	6.7	30.5	4.5	15.3	12.0	13.5	29.0	59.1	1.4	0.0	48.0	44.4	0.1	18.4	47.0	19.2	37.1	139.4	24.9	0.0	46.8	43.4	38.2	29.8	43.4	16.4	20.9	0.0	24.4	0.0	33.8	0.0	61.4	14.3	50.3	49.0	32.3	38.7	26.3	32.1	30.4	0.0	20.4	0.1	26.4	32.7	0.0	16.2	0.0	158.3	23.0	0.0	48.5	27.9	56.8	13.7	5.8	14.9	31.2	45.7	1.0	25.0	0.0	34.5	32.4	11.9	14.1	3.9	0.1	10.9	13.3	0.1	0.0	0.0	35.9	0.0	1.6	0.0	0.8	0.3	16.0	0.0	0.2	2.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.5	13.4	15.4	14.5	18.1	13.1	17.4	15.0	19.1	18.3	13.4	16.8	13.5	0.9	19.2	12.1	71.8	0.6	1.9	5.1	12.5	6.8	17.1	2.5	0.9	41.0	7.2	12.7	5.5	2.1	0.6	0.5	12.7	1.9	12.3	5.5	0.7	6.8	2.3	0.0	0.0	117.1	9.5	0.9	8.5	62.7	0.2	0.0	11.2	4.2	12.1	7.1	13.5	70.6	4.1	8.2	74.4	25.6	6.5	25.7	16.7	0.0	23.4	5.5	100.6	0.0	123.6	38.6	15.0	4.5	37.2	0.5	5.2	15.2	3.1	7.2	7.5	0.0	4.5	8.3	7.5	2.3	22.3	3.4	0.8	1.8	33.6	8.9	3.3
ME2		ENSG00000082212	"Malic enzyme 2"	P23368	18	50879080-50954257	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Allosteric enzyme, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Granulosa cells: 176.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA008247, HPA008880"	Enhanced		Supported	Mitochondria		NA	NA		84000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 40: Granulosa cells - Unknown function"	Mitochondria		"HPA008247: AB_1853704, HPA008880: AB_1853702"	"unprognostic (1.23e-1)"	"unprognostic (3.26e-1)"	"unprognostic (9.57e-3)"	"unprognostic (2.22e-1)"	"unprognostic (4.97e-2)"	"unprognostic (1.23e-1)"	"prognostic unfavorable (8.29e-8)"	"unprognostic (1.97e-1)"	"unprognostic (3.66e-2)"	"unprognostic (1.02e-1)"	"unprognostic (1.34e-2)"	"unprognostic (4.75e-2)"	"unprognostic (1.43e-2)"	"unprognostic (4.27e-3)"	"unprognostic (2.30e-1)"	"unprognostic (2.47e-1)"	"unprognostic (4.09e-1)"	12.1	15.7	12.7	21.9	13.6	15.6	9.3	14.1	16.8	8.9	55.5	30.6	38.3	9.0	8.9	12.8	8.5	12.7	45.0	14.8	15.4	12.6	15.1	11.6	25.8	15.6	16.2	8.0	20.9	32.2	10.0	13.1	16.2	13.8	32.4	14.6	7.2	19.9	26.2	8.8	32.3	18.1	13.9	27.2	26.5	18.8	15.4	21.4	10.9	22.9	22.6	16.8	3.4	14.3	40.5	39.9	52.0	61.0	23.2	25.6	24.2	33.2	24.7	42.2	35.5	18.4	21.8	143.3	12.8	29.7	38.5	32.6	78.1	33.3	48.2	60.0	11.6	36.5	22.8	21.5	68.1	123.9	42.5	16.0	40.3	53.1	85.8	27.8	55.0	83.5	39.9	34.1	29.1	8.4	90.4	12.3	34.8	29.0	15.9	58.0	25.8	41.1	45.9	8.6	63.9	34.0	31.0	18.7	33.0	31.0	14.4	59.0	34.6	30.0	32.7	15.8	44.7	62.9	27.1	70.6	30.2	86.5	32.5	7.5	16.4	20.7	6.5	19.0	5.1	7.1	4.2	7.9	13.3	7.2	3.6	4.5	18.1	9.8	25.7	4.4	4.4	7.4	12.7	13.6	14.1	16.8	14.8	15.4	15.6	16.2	16.2	13.9	15.4	14.3	20.9	9.6	11.9	40.1	32.8	15.2	20.2	13.6	12.5	17.0	10.9	10.0	103.6	11.5	22.6	14.7	14.6	16.7	37.9	39.0	39.2	31.9	18.0	18.5	22.6	18.7	12.0	16.6	35.6	38.6	16.3	19.1	43.3	19.1	16.4	176.4	24.3	9.1	89.7	8.4	45.9	27.3	18.3	93.8	15.1	6.7	11.5	54.5	12.4	47.8	48.3	18.0	48.4	52.3	32.5	35.6	22.3	16.6	61.5	25.0	72.4	17.1	10.6	55.0	6.6	23.0	23.2	59.8	30.6	13.2	10.7	8.6	28.1	22.4	36.5	17.4
ME3		ENSG00000151376	"Malic enzyme 3"	Q16798	11	86441108-86672636	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 54.2;Excitatory neurons: 103.7;Inhibitory neurons: 147.8;Oligodendrocyte precursor cells: 75.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"myeloid DC: 2.3"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"CAPAN-2: 54.4;hTERT-RPE1: 64.1;HUVEC TERT2: 36.3;TIME: 40.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in single"			HPA038473	Approved					NA	NA			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 35: Non-specific - Unknown function"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"			"HPA038473: AB_10672747"	"unprognostic (1.83e-3)"	"unprognostic (8.00e-2)"	"unprognostic (1.99e-1)"	"unprognostic (1.04e-1)"	"unprognostic (2.13e-1)"	"unprognostic (2.91e-1)"	"unprognostic (5.01e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.29e-1)"	"unprognostic (2.71e-1)"	"unprognostic (1.20e-1)"	"unprognostic (5.74e-2)"	"unprognostic (2.97e-1)"	"unprognostic (1.65e-1)"	"unprognostic (2.73e-1)"	"unprognostic (2.96e-2)"	"prognostic favorable (3.86e-4)"	17.4	24.4	25.5	5.0	27.2	6.2	19.5	12.2	31.5	24.5	14.4	16.4	7.1	16.7	5.6	4.2	13.6	11.5	26.2	27.0	15.7	25.1	6.2	11.3	4.2	24.8	25.9	27.9	15.9	16.2	22.4	4.7	22.9	19.9	13.7	10.8	12.6	9.0	21.9	4.5	8.9	14.1	5.3	10.9	21.0	13.0	20.4	3.5	12.5	19.5	2.4	17.1	14.2	16.5	0.0	18.1	5.2	0.0	7.9	16.6	0.1	5.9	9.6	12.9	16.0	14.0	54.4	0.0	5.3	5.7	31.5	0.2	0.0	0.1	5.6	9.2	0.0	9.6	16.8	0.0	11.9	1.2	0.0	11.8	2.8	10.2	0.1	64.1	36.3	0.0	0.2	0.0	9.1	1.8	2.7	0.1	1.2	1.7	7.7	8.3	0.0	0.6	11.4	21.4	6.2	0.1	3.8	0.1	0.0	2.1	0.9	1.5	40.0	1.5	1.2	26.3	0.9	0.1	3.3	0.0	1.4	17.1	1.6	0.0	0.3	0.0	0.7	0.0	0.0	0.0	0.7	1.2	2.3	0.0	0.9	1.1	0.0	1.0	0.1	0.3	0.0	0.5	25.5	27.2	12.2	31.5	27.0	15.7	24.8	25.9	22.9	5.3	20.4	16.5	13.6	3.2	3.3	30.3	1.1	2.3	4.6	5.4	5.7	16.5	7.5	9.1	54.2	2.8	8.1	3.7	0.0	0.3	1.9	19.2	43.0	9.1	0.7	3.2	6.1	11.5	9.0	4.2	103.7	7.9	0.4	8.4	19.9	1.6	0.0	33.4	14.6	1.6	6.8	20.2	147.8	14.8	4.1	1.6	3.5	2.5	6.2	1.8	1.8	14.0	1.1	2.0	1.0	75.4	4.8	11.5	21.1	6.4	0.5	6.4	3.5	6.5	14.9	2.5	13.1	7.0	8.2	0.4	0.2	2.6	1.6	0.0	1.6	38.8	11.0	6.6
MECR	"CGI-63, ETR1, FASN2B, NRBF1"	ENSG00000116353	"Mitochondrial trans-2-enoyl-CoA reductase"	Q9BV79	1	29192657-29230942	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	Oxidoreductase	"Disease variant, Dystonia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 42.1"	"Cell type enhanced"	"Detected in all"		"Late spermatids: 82.5;Rod photoreceptor cells: 68.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"HPA022018, HPA022030, HPA028740"	Enhanced		Supported	Mitochondria		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 59: Non-specific - Translation"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 46: Photoreceptor cells - Phototransduction"	Mitochondria		"HPA022018: AB_1853714, HPA022030: AB_1853716, HPA028740: AB_10601133"	"unprognostic (2.53e-1)"	"unprognostic (1.09e-2)"	"unprognostic (1.52e-1)"	"unprognostic (1.84e-1)"	"unprognostic (1.07e-1)"	"unprognostic (2.46e-1)"	"unprognostic (1.39e-1)"	"unprognostic (2.07e-1)"	"unprognostic (1.34e-1)"	"unprognostic (1.69e-1)"	"unprognostic (3.06e-2)"	"unprognostic (8.66e-2)"	"prognostic favorable (5.81e-6)"	"unprognostic (7.01e-3)"	"unprognostic (3.29e-2)"	"unprognostic (2.59e-1)"	"prognostic unfavorable (5.29e-4)"	14.7	14.6	5.1	1.7	5.1	1.8	13.4	3.3	6.2	10.2	3.1	10.3	1.4	12.9	2.5	12.5	9.4	1.3	24.8	6.0	3.9	14.1	15.8	7.3	2.0	5.2	4.0	10.0	8.9	4.5	7.2	3.5	5.4	7.9	2.6	9.9	12.3	3.0	42.1	15.4	7.2	3.1	3.2	6.7	11.1	7.6	4.3	1.4	8.3	5.8	2.1	9.6	9.6	5.2	3.9	4.5	3.2	4.6	2.9	2.5	6.8	3.7	3.8	4.7	3.9	2.3	5.6	7.3	5.1	3.7	1.3	3.0	5.4	6.3	4.0	4.4	6.9	6.4	3.4	4.1	6.6	6.1	1.9	4.3	5.9	3.1	11.0	3.8	3.5	6.9	5.8	4.2	4.7	4.5	3.9	2.9	6.5	5.8	4.3	3.5	4.2	9.3	5.9	2.4	5.1	4.5	4.1	4.7	7.0	4.4	2.3	5.4	3.8	2.4	2.9	4.1	4.7	2.7	2.2	5.0	3.9	8.4	5.2	0.1	2.2	0.0	1.5	2.1	4.1	2.2	1.6	1.7	1.9	1.1	2.3	1.6	0.3	2.9	1.6	2.5	2.4	1.2	5.1	5.1	3.3	6.2	6.0	3.9	5.2	4.0	5.4	3.2	4.3	5.2	8.8	12.8	3.9	14.7	9.1	5.6	15.6	26.9	7.4	12.8	12.0	14.6	19.8	21.5	21.4	20.2	10.4	46.0	3.8	7.4	41.1	24.3	40.8	19.7	13.6	9.1	7.8	10.1	25.1	19.7	42.4	12.8	4.6	12.8	5.7	17.5	7.1	19.7	20.8	8.4	20.3	9.4	12.2	6.0	5.1	82.5	13.7	5.3	16.0	3.7	10.8	14.5	10.3	11.6	15.2	16.3	8.0	10.9	10.3	20.6	10.9	46.0	11.3	68.5	13.1	13.2	12.9	8.5	16.1	14.0	7.4	27.9	6.0	25.8	18.3	20.5
MICAL1	"DKFZp434B1517, FLJ11937, FLJ21739, MICAL, NICAL"	ENSG00000135596	"Microtubule associated monooxygenase, calponin and LIM domain containing 1"	Q8TDZ2	6	109444062-109465968	"Enzymes, Predicted intracellular proteins"		"Actin-binding, Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Gastric mucus-secreting cells: 76.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"THP-1: 148.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA030175, HPA030176, HPA030178"	Approved					NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 45: Enterocytes - Digestion"			"HPA030175: AB_2673359, HPA030176: AB_2673360, HPA030178: AB_10600824"	"unprognostic (1.07e-2)"	"unprognostic (1.86e-1)"	"unprognostic (1.23e-1)"	"unprognostic (2.17e-1)"	"unprognostic (2.21e-1)"	"unprognostic (2.71e-3)"	"unprognostic (1.52e-2)"	"unprognostic (1.92e-2)"	"unprognostic (6.93e-2)"	"unprognostic (1.94e-1)"	"prognostic favorable (2.63e-7)"	"unprognostic (2.31e-1)"	"prognostic unfavorable (6.71e-7)"	"unprognostic (2.05e-1)"	"unprognostic (3.27e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.22e-1)"	20.6	6.3	17.8	27.6	17.5	65.9	14.2	17.8	25.6	48.6	16.1	21.7	37.8	29.6	2.5	11.8	32.7	14.7	11.1	17.8	19.9	18.8	5.4	35.2	32.8	20.7	18.4	13.6	8.7	9.2	17.9	10.7	20.6	30.8	10.1	6.2	11.0	18.8	5.1	16.0	43.2	9.1	18.1	56.7	18.3	18.7	20.3	18.3	12.6	3.9	16.6	62.2	30.8	22.4	4.1	5.1	15.8	0.2	55.9	43.6	10.7	31.3	22.0	6.7	11.0	7.3	4.7	23.2	6.6	33.1	19.4	5.4	9.6	12.3	2.8	20.3	4.0	9.9	12.0	11.5	22.8	6.5	0.3	25.7	6.2	15.5	12.6	25.2	20.0	14.0	2.7	40.2	40.6	5.1	8.0	36.0	9.9	5.5	5.4	21.9	10.0	3.3	15.0	10.0	5.3	28.1	2.9	2.7	50.4	10.0	4.9	148.8	21.6	16.7	5.9	9.8	12.2	29.7	9.6	20.8	13.9	21.4	12.3	14.6	7.3	13.6	6.5	13.2	3.9	3.5	6.4	5.2	12.8	5.1	4.3	3.1	9.3	5.1	14.2	14.4	9.4	6.8	17.8	17.5	17.8	25.6	17.8	19.9	20.7	18.4	20.6	18.1	20.3	22.4	5.3	44.8	14.4	3.3	26.2	6.1	1.3	2.3	1.2	3.4	2.5	3.6	4.4	0.0	4.2	1.8	4.2	1.3	31.0	24.9	1.9	7.8	13.2	2.0	29.8	5.9	32.2	4.6	13.8	6.5	10.9	9.7	76.9	2.4	15.2	3.1	4.6	0.3	32.2	0.0	12.9	34.9	6.1	28.3	44.5	23.1	20.8	34.7	16.0	8.4	34.0	2.2	21.6	12.5	4.2	11.6	27.6	37.6	15.4	1.3	49.6	4.6	10.7	18.3	0.0	31.6	27.3	7.9	9.5	0.7	4.8	4.8	22.5	2.9	13.9	1.5
MICAL2	KIAA0750	ENSG00000133816	"Microtubule associated monooxygenase, calponin and LIM domain containing 2"	O94851	11	12094008-12359144	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"		"Actin-binding, Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 61.6"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 193.5;Inhibitory neurons: 108.8;Late spermatids: 192.7;Peritubular cells: 112.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 8.9"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"U-138 MG: 109.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA030437, HPA039895, HPA040438"	Approved		Uncertain	"Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol"		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 58: Brain - Synaptic function"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	"Golgi apparatus, Cytosol"	"Nucleoplasm, Plasma membrane"	"HPA030437: AB_10601873, HPA039895: AB_2676731, HPA040438: AB_10672896"	"unprognostic (2.68e-2)"	"unprognostic (1.77e-2)"	"unprognostic (5.77e-2)"	"unprognostic (1.31e-1)"	"prognostic unfavorable (6.88e-4)"	"unprognostic (2.20e-2)"	"unprognostic (3.60e-2)"	"unprognostic (9.32e-2)"	"unprognostic (2.86e-1)"	"unprognostic (1.36e-1)"	"unprognostic (1.15e-2)"	"unprognostic (6.47e-2)"	"prognostic unfavorable (3.63e-5)"	"unprognostic (4.61e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.21e-1)"	"unprognostic (1.67e-1)"	4.7	3.8	13.9	12.2	13.6	11.6	2.5	61.6	38.1	6.9	42.6	18.8	9.8	12.3	7.2	18.6	7.4	10.0	42.2	37.8	0.0	2.3	2.9	17.5	3.3	0.0	0.0	3.9	4.1	1.0	0.2	7.3	0.0	2.9	16.3	4.0	0.8	9.6	16.8	14.0	10.8	30.8	0.0	3.3	6.7	32.5	0.0	1.9	6.1	4.1	2.5	12.4	0.3	19.9	29.1	9.7	0.4	2.7	2.3	6.8	14.2	32.1	53.7	16.2	28.3	24.3	23.3	0.2	8.4	25.3	47.7	25.0	4.0	65.1	41.6	35.9	4.8	27.5	4.1	0.9	12.8	5.3	2.7	12.7	11.1	76.0	54.6	25.3	46.9	1.6	43.5	0.8	22.9	1.2	0.3	1.6	1.2	13.6	9.8	0.3	15.2	14.2	2.1	35.5	14.3	0.8	8.6	38.6	2.9	9.9	4.5	2.3	42.6	109.6	35.0	17.4	39.6	0.9	2.6	1.5	64.3	5.2	1.4	0.1	4.2	0.5	1.3	0.7	1.5	0.1	0.8	0.4	3.4	0.2	0.0	0.4	8.9	2.2	0.4	0.9	0.7	1.5	13.9	13.6	61.6	38.1	37.8	0.0	0.0	0.0	0.0	0.0	0.0	19.9	3.2	41.7	37.1	7.2	1.2	10.1	11.8	4.5	4.0	5.7	4.2	5.3	32.2	7.2	8.5	3.7	0.0	2.6	11.2	66.5	0.0	10.2	74.4	7.8	8.9	9.2	22.6	35.6	193.5	14.3	12.6	9.0	12.2	11.4	1.3	1.4	12.8	19.6	3.4	0.0	108.8	10.6	6.1	10.1	5.6	192.7	21.1	11.1	5.4	4.7	21.6	0.5	8.2	6.6	17.5	42.5	24.0	112.8	2.1	8.9	18.3	0.9	5.5	1.6	13.1	1.9	29.4	1.2	1.3	1.7	9.5	2.3	10.8	0.7	14.5	11.9
MICAL3	KIAA0819	ENSG00000243156	"Microtubule associated monooxygenase, calponin and LIM domain containing 3"	Q7RTP6	22	17787649-18024561	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"	"Cell cycle, Cell division, Exocytosis"	"Actin-binding, Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 104.9"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 176.5;Inhibitory neurons: 164.6;Oligodendrocytes: 216.0"	"Low cancer specificity"	"Detected in all"			"Region enhanced"	"Detected in all"		"cerebellum: 104.9"	"Immune cell enriched"	"Detected in some"	4	"basophil: 11.1"	"Lineage enriched"	"Detected in many"	4	"granulocytes: 11.1"	"Cell line enhanced"	"Detected in all"		"WM-115: 131.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000639, HPA003421, HPA034882"	Approved		Supported	"Nucleoplasm,Plasma membrane,Midbody ring,Cytosol"		Yes	No			"Cluster 38: Basophils - Unknown function"	"Cluster 21: Non-specific - Transcription"	"Cluster 17: WM-115 - Nervous system development"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	"Nucleoplasm, Midbody ring"	"Plasma membrane, Cytosol"	"HPA000639: AB_10301319, HPA003421: AB_10601134, HPA034882: AB_2674371"	"unprognostic (1.65e-1)"	"unprognostic (1.02e-1)"	"unprognostic (3.67e-2)"	"unprognostic (2.00e-2)"	"unprognostic (7.68e-2)"	"unprognostic (2.06e-1)"	"unprognostic (4.71e-2)"	"unprognostic (3.07e-3)"	"unprognostic (3.41e-1)"	"unprognostic (1.01e-1)"	"unprognostic (4.58e-1)"	"unprognostic (3.82e-1)"	"unprognostic (8.86e-3)"	"unprognostic (1.36e-2)"	"unprognostic (1.23e-1)"	"unprognostic (2.03e-2)"	"unprognostic (6.64e-2)"	15.9	12.0	18.3	14.9	20.3	17.3	11.2	104.9	34.5	16.5	3.6	28.1	11.0	31.0	17.0	19.6	38.6	13.4	35.6	14.3	13.7	10.9	18.8	8.3	23.0	13.2	6.4	26.5	14.0	38.5	7.2	16.7	15.6	16.4	20.6	14.1	10.9	19.8	48.2	18.9	14.5	37.3	1.9	17.8	10.7	24.4	12.7	6.0	14.7	20.8	20.3	15.9	12.0	45.9	34.0	39.6	20.2	33.7	15.6	19.2	25.6	32.6	33.1	43.6	34.5	36.1	4.8	35.1	15.5	39.3	51.2	38.7	30.1	31.9	43.0	35.6	25.2	35.9	44.6	11.9	9.6	17.1	20.2	14.4	25.9	46.9	43.7	25.2	24.9	9.7	47.6	22.8	16.9	26.6	16.9	10.7	13.0	27.3	26.4	23.2	30.3	1.9	32.1	24.8	53.5	21.1	40.6	26.0	65.2	31.5	10.8	7.0	43.9	46.0	28.4	29.7	63.6	16.4	30.2	50.8	40.0	7.7	131.6	11.1	0.0	0.1	0.3	0.0	0.6	2.5	0.3	0.3	0.0	2.6	0.2	0.1	0.1	0.9	0.0	0.2	0.7	0.2	18.3	20.3	104.9	34.5	14.3	13.7	13.2	6.4	15.6	1.9	12.7	45.9	19.6	3.2	10.2	57.1	32.1	11.2	15.2	17.9	13.1	20.9	13.7	15.5	16.5	12.8	13.2	12.9	52.1	14.1	6.2	43.5	0.0	23.9	10.5	36.4	10.2	16.4	10.2	19.3	176.5	9.8	40.3	10.5	13.3	38.8	19.0	9.7	8.9	37.3	3.1	1.7	164.6	20.8	8.2	3.2	9.6	13.9	4.1	4.2	8.8	23.4	6.0	38.2	5.2	71.9	216.0	24.6	23.6	6.4	12.5	14.4	19.8	5.5	27.8	12.2	0.0	11.0	12.1	19.8	13.8	11.2	11.8	11.2	9.1	24.2	21.5	10.1
MIOX	ALDRL6	ENSG00000100253	"Myo-inositol oxygenase"	Q9UGB7	22	50486784-50490648	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	48	"kidney: 700.9"	"Cell type enriched"	"Detected in some"	10	"Proximal tubular cells: 4564.6"	"Cancer enriched"	"Detected in many"	16	"renal cancer: 56.0"	"Not detected"	"Not detected"			"Immune cell enhanced"	"Detected in single"		"basophil: 1.0"	"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in some"		"HDLM-2: 24.9;Hep G2: 5.7;Karpas-707: 12.8;U-266/70: 7.8"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA039451, HPA039562"	Enhanced					NA	NA			"Cluster 18: Basophils - Vesicular transport"	"Cluster 7: Kidney - Transmembrane transport"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA039451: AB_2676513, HPA039562: AB_2676574"	"unprognostic (2.11e-1)"	"unprognostic (4.32e-2)"	"unprognostic (2.22e-2)"	"unprognostic (1.30e-2)"	"unprognostic (9.83e-2)"	"unprognostic (5.25e-2)"	"unprognostic (1.61e-2)"	"unprognostic (3.84e-3)"	"unprognostic (2.84e-1)"	"unprognostic (4.72e-2)"	"unprognostic (1.85e-2)"	"unprognostic (9.83e-2)"	"prognostic favorable (2.60e-6)"	"unprognostic (1.77e-1)"	"unprognostic (1.50e-1)"	"unprognostic (1.36e-2)"	"unprognostic (2.23e-2)"	0.2	0.1	0.1	0.3	0.2	0.2	0.0	0.8	0.5	0.0	0.2	0.8	0.2	0.0	0.2	0.1	0.0	5.3	0.0	0.2	0.2	700.9	0.4	0.0	0.7	0.2	0.2	0.0	1.2	0.0	0.1	0.1	0.3	0.5	0.0	0.1	0.3	0.1	0.0	0.3	0.2	0.0	0.1	0.2	1.1	0.2	0.2	0.2	14.7	0.0	0.2	0.1	0.0	0.3	0.0	0.0	0.1	0.3	0.2	0.1	2.0	0.2	0.0	0.0	0.1	0.1	0.2	0.1	0.6	0.4	0.0	0.2	0.2	0.0	0.0	24.9	0.0	0.2	0.4	5.7	2.8	0.0	0.2	0.0	0.0	0.1	0.4	0.0	0.0	1.1	0.1	12.8	0.0	1.2	0.0	0.1	0.2	0.5	0.4	0.1	0.1	0.1	2.6	0.1	0.1	0.3	0.0	0.0	0.6	0.5	0.1	1.4	0.0	0.0	0.5	0.1	0.1	7.8	0.7	0.3	0.1	0.0	0.2	1.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.2	0.0	0.1	0.0	0.1	0.2	0.0	0.1	0.1	0.0	0.1	0.1	0.2	0.8	0.5	0.2	0.2	0.2	0.2	0.3	0.1	0.2	0.3	0.2	0.0	1.7	0.0	13.0	0.8	0.9	0.1	0.0	0.6	0.7	0.8	0.1	1.5	0.0	99.3	0.0	0.0	0.3	0.3	424.6	0.0	0.0	0.1	0.2	0.2	1.2	0.0	0.0	0.9	0.1	0.3	0.0	0.2	0.0	0.1	0.4	0.3	0.1	0.0	0.0	0.9	0.0	0.0	1.6	0.0	0.0	23.9	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.3	0.2	4564.6	0.0	0.5	0.0	0.2	0.1	0.1	0.3	0.0	0.1	0.3	7.8	0.0	0.1	0.9
MMACHC	"cblC, DKFZP564I122"	ENSG00000132763	"Metabolism of cobalamin associated C"	Q9Y4U1	1	45500300-45513382	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		"Oxidoreductase, Transferase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 17.4"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 22.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA027394, HPA027399, HPA027402"	Uncertain		Supported	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 59: Non-specific - Transcription"	Nucleoplasm	"Plasma membrane, Cytosol"	"HPA027394: AB_10601669, HPA027399: AB_10601987, HPA027402: AB_2672255"	"unprognostic (3.34e-1)"	"unprognostic (1.63e-1)"	"unprognostic (7.03e-3)"	"unprognostic (3.14e-2)"	"unprognostic (4.05e-1)"	"unprognostic (1.16e-2)"	"unprognostic (9.04e-2)"	"unprognostic (1.03e-2)"	"unprognostic (1.90e-1)"	"unprognostic (1.05e-2)"	"unprognostic (3.88e-2)"	"unprognostic (6.81e-2)"	"unprognostic (2.61e-3)"	"unprognostic (2.08e-3)"	"unprognostic (8.83e-2)"	"unprognostic (2.50e-2)"	"unprognostic (2.58e-2)"	2.0	3.1	3.3	1.7	5.3	1.2	3.5	5.1	4.2	2.9	2.3	3.7	3.3	1.7	3.0	2.8	3.5	1.3	6.9	3.4	5.1	3.5	17.4	1.2	1.8	4.1	5.6	3.5	2.9	5.5	1.3	1.5	3.9	2.0	4.4	2.1	5.0	2.4	10.8	2.0	2.4	2.3	3.5	1.6	2.3	4.3	5.6	2.2	2.3	6.6	2.0	1.7	1.5	6.0	7.7	3.9	6.6	10.0	6.1	3.7	8.1	5.9	3.9	10.5	9.4	8.3	4.7	12.0	7.4	4.9	2.0	6.2	12.3	14.0	9.6	3.3	11.4	9.4	6.5	9.2	5.8	13.5	3.3	5.3	7.8	11.6	12.6	3.7	5.1	12.5	10.8	6.7	8.1	8.2	9.1	4.3	10.9	8.8	8.9	11.1	2.7	13.2	6.2	6.0	10.5	5.4	8.8	14.5	19.3	4.9	8.3	4.6	2.3	7.3	9.9	8.3	3.3	9.9	8.5	6.9	5.3	6.4	6.9	2.3	0.5	0.5	0.5	0.8	0.8	0.7	0.7	0.4	0.6	0.6	1.3	0.6	0.9	0.8	2.7	1.3	0.4	0.4	3.3	5.3	5.1	4.2	3.4	5.1	4.1	5.6	3.9	3.5	5.6	6.0	1.1	3.2	5.5	1.6	2.1	0.1	1.8	0.8	5.7	1.3	2.7	1.5	9.8	4.3	2.2	1.8	0.0	3.7	0.6	2.8	5.9	1.3	1.0	3.6	4.8	1.5	4.2	4.8	2.6	1.4	4.3	3.6	7.1	3.2	2.5	2.9	2.5	22.9	3.3	3.3	2.7	3.2	2.0	3.2	0.9	1.2	1.8	2.7	0.0	0.0	0.6	1.4	3.1	1.5	5.3	1.8	2.3	1.5	10.4	1.7	2.0	4.6	1.2	5.2	0.0	5.0	2.4	7.4	2.1	11.5	0.1	2.7	2.4	3.9	5.8	1.8
MPO		ENSG00000005381	Myeloperoxidase	P05164	17	58269855-58280935	"Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Hydrogen peroxide"	"Oxidoreductase, Peroxidase"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	61	"bone marrow: 4023.1"	"Cell type enriched"	"Detected in some"	30	"Erythroid cells: 87.4"	"Cancer enhanced"	"Detected in single"		"stomach cancer: 1.1"	"Low region specificity"	"Detected in some"			"Immune cell enhanced"	"Detected in some"		"classical monocyte: 6.2"	"Low lineage specificity"	"Detected in many"			"Group enriched"	"Detected in some"	94	"HL-60: 3517.4;NB-4: 4589.9"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"CAB000059, HPA021147, HPA061464"	Enhanced		Supported	Nucleoplasm,Vesicles	"Intracellular and membrane"	No	NA	576000000	24000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 24: NB-4 - Immune response"	"Cluster 12: Non-specific - Cell cycle regulation"	Vesicles	Nucleoplasm	"CAB000059: AB_2335676, HPA021147: AB_1854083, HPA061464: AB_2684531"	"unprognostic (1.91e-1)"	"unprognostic (9.08e-2)"	"unprognostic (4.62e-2)"	"unprognostic (2.90e-2)"	"unprognostic (2.13e-3)"	"unprognostic (2.78e-1)"	"unprognostic (3.23e-1)"	"unprognostic (2.91e-1)"	"unprognostic (2.56e-1)"	"unprognostic (1.68e-1)"	"unprognostic (6.92e-2)"	"unprognostic (8.34e-3)"	"unprognostic (4.91e-2)"	"unprognostic (3.07e-3)"	"unprognostic (2.83e-1)"	"unprognostic (1.14e-2)"	"unprognostic (8.05e-2)"	0.5	0.4	0.8	0.6	0.6	4023.1	0.3	0.6	1.1	0.0	0.3	0.2	0.0	0.2	1.1	0.1	0.1	0.3	1.1	0.8	0.7	0.2	1.8	8.4	1.7	0.9	1.0	0.1	0.1	0.0	1.5	1.4	0.9	0.2	0.2	0.4	66.3	0.1	1.1	4.3	0.2	0.3	0.8	21.7	0.1	0.4	0.8	10.9	0.3	0.3	0.2	0.5	0.1	0.7	0.4	0.0	0.0	0.0	0.0	0.0	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.1	3517.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4589.9	0.0	0.0	0.0	5.3	3.2	0.6	0.0	0.0	0.0	0.5	1.1	0.0	0.0	0.0	0.0	43.1	0.0	0.0	0.0	1.3	0.0	0.0	0.0	1.1	0.0	4.0	0.0	0.0	6.2	0.0	0.0	3.0	0.0	0.0	0.0	0.0	2.4	0.0	0.0	0.0	1.4	0.0	0.6	0.0	0.1	7.5	0.8	0.6	0.6	1.1	0.8	0.7	0.9	1.0	0.9	0.8	0.8	0.7	0.0	0.0	0.5	0.7	0.3	0.0	0.0	0.0	0.0	0.4	0.2	0.3	0.4	0.0	0.0	0.0	0.0	0.0	1.8	0.0	1.9	0.0	0.5	0.1	0.0	0.1	0.0	87.4	0.3	0.2	0.9	0.7	0.0	0.0	0.0	0.0	0.7	0.3	0.9	0.0	0.2	0.0	0.0	1.2	0.0	1.3	0.0	2.9	0.0	0.0	2.3	0.2	0.0	0.0	0.0	0.0	0.0	0.4	0.1	0.0	0.0	0.0	0.0	0.2	0.0	1.2	0.1	0.1	0.3	0.1	0.0	0.1	0.6	0.0	0.0	0.0
MSMO1	"DESP4, ERG25, SC4MOL"	ENSG00000052802	"Methylsterol monooxygenase 1"	Q15800	4	165327667-165343164	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Oxidoreductase	"Cataract, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 575.6"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 532.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"GAMG: 416.2;Karpas-707: 412.3;RPTEC TERT1: 399.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA055073, HPA056127"	Enhanced		Approved	"Endoplasmic reticulum"		NA	NA			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 85: Liver - Metabolism"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 15: Hepatocytes - Hemostasis"	"Endoplasmic reticulum"		"HPA055073: , HPA056127: AB_2683045"	"unprognostic (5.76e-2)"	"prognostic unfavorable (2.97e-4)"	"unprognostic (3.35e-2)"	"unprognostic (7.85e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.20e-2)"	"unprognostic (7.14e-2)"	"unprognostic (1.75e-2)"	"unprognostic (3.52e-2)"	"unprognostic (2.06e-1)"	"unprognostic (3.22e-3)"	"unprognostic (2.28e-1)"	"prognostic favorable (9.21e-4)"	"unprognostic (2.39e-1)"	"unprognostic (1.56e-2)"	"unprognostic (3.54e-1)"	"unprognostic (1.40e-1)"	18.3	95.2	36.7	20.9	48.2	10.4	66.2	45.1	47.5	57.1	37.4	39.2	75.7	19.1	97.0	145.7	20.9	21.7	18.5	43.9	59.2	52.6	575.6	70.3	20.7	90.5	58.4	25.7	22.6	42.9	18.4	22.9	78.6	58.9	32.9	26.1	34.7	12.1	5.5	82.5	38.1	16.5	45.0	11.0	31.5	52.8	48.4	13.4	22.4	6.5	27.0	20.2	67.0	61.1	89.1	21.7	198.8	36.4	97.7	312.0	37.5	35.3	159.0	44.7	123.4	41.5	372.9	43.4	20.6	43.1	416.2	71.7	101.6	366.3	49.4	37.7	63.0	20.0	20.0	127.6	194.9	35.8	26.8	192.6	237.6	163.6	100.6	61.1	58.8	55.7	35.3	412.3	74.6	45.7	32.6	58.2	115.6	46.9	21.0	16.8	21.8	132.3	399.5	102.5	39.7	30.0	54.5	77.9	33.9	121.7	36.1	44.7	67.6	20.6	36.1	18.5	24.7	75.9	86.5	58.6	43.9	36.0	28.5	13.7	8.6	8.8	34.0	11.6	25.4	40.6	31.8	31.4	15.0	37.6	34.3	35.6	6.1	24.9	20.5	19.3	31.0	29.2	36.7	48.2	45.1	47.5	43.9	59.2	90.5	58.4	78.6	45.0	48.4	61.1	16.9	51.3	168.0	70.5	28.9	36.1	70.1	189.2	21.6	33.8	81.9	23.0	10.7	40.0	160.0	69.9	27.1	55.6	20.7	130.8	35.2	67.9	6.4	27.6	12.2	30.4	60.7	53.9	33.6	71.7	87.0	24.1	35.2	44.4	47.7	83.0	27.8	532.0	28.3	35.3	22.8	72.8	170.9	28.0	11.5	7.0	24.8	18.3	32.0	10.3	23.6	27.2	17.5	42.7	49.6	86.8	85.7	18.8	10.9	138.3	46.0	38.4	103.2	50.4	19.7	5.6	35.1	8.7	15.4	84.6	115.1	123.0	22.3	136.1	36.9	129.0
MSRA		ENSG00000175806	"Methionine sulfoxide reductase A"	Q9UJ68	8	10054292-10428891	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"kidney: 86.0;liver: 64.0"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 625.8;Inhibitory neurons: 318.6;Oligodendrocyte precursor cells: 268.9;Proximal tubular cells: 666.1"	"Low cancer specificity"	"Detected in all"			"Region enriched"	"Detected in many"	5	"cerebellum: 28.4"	"Immune cell enhanced"	"Detected in some"		"eosinophil: 5.6"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"HMC-1: 12.3"	"Low region specificity"	"Detected in all"							"HPA023804, HPA075766"	Approved		Supported	"Nucleoplasm,Plasma membrane,Actin filaments,Cytosol"	"Intracellular and membrane"	No	No		55000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	"Nucleoplasm, Cytosol"	"Plasma membrane, Actin filaments"	"HPA023804: AB_1853826, HPA075766: "	"unprognostic (1.55e-1)"	"unprognostic (4.30e-3)"	"unprognostic (1.45e-3)"	"unprognostic (1.00e-2)"	"unprognostic (4.21e-2)"	"unprognostic (1.62e-2)"	"unprognostic (1.49e-2)"	"unprognostic (6.40e-2)"	"unprognostic (9.69e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.80e-1)"	"unprognostic (4.58e-2)"	"unprognostic (1.07e-3)"	"unprognostic (6.43e-3)"	"unprognostic (4.02e-1)"	"unprognostic (6.36e-3)"	"unprognostic (3.07e-1)"	17.0	20.4	2.2	1.1	3.0	13.5	16.1	28.4	5.4	9.1	0.0	13.9	1.1	10.7	0.1	11.6	7.4	0.4	29.0	3.8	0.0	86.0	64.0	12.2	0.6	0.0	0.4	6.4	14.5	0.7	9.2	0.8	1.8	9.2	0.6	0.6	10.5	1.0	14.5	9.5	20.1	0.8	0.0	18.6	14.2	15.2	0.3	1.5	9.6	1.3	0.6	11.6	8.2	2.8	0.1	0.9	1.3	4.3	1.2	1.4	0.5	2.5	0.2	0.3	1.7	0.6	2.1	0.0	0.6	2.5	5.8	2.3	0.4	0.1	1.3	0.2	0.0	0.3	1.5	2.2	4.3	0.8	12.3	0.4	3.2	0.3	0.0	1.4	0.6	0.3	0.4	0.2	4.9	0.1	0.0	0.3	0.6	3.3	0.8	1.6	1.3	2.0	1.1	1.1	2.5	1.5	4.6	0.2	0.5	0.4	2.3	2.8	2.6	1.7	2.0	0.4	1.2	0.2	0.1	0.7	4.8	0.8	3.1	0.5	1.9	5.6	0.4	1.2	0.3	0.6	0.4	0.3	1.2	0.1	0.3	0.2	2.2	0.7	0.9	0.2	0.3	0.2	2.2	3.0	28.4	5.4	3.8	0.0	0.0	0.4	1.8	0.0	0.3	2.8	44.1	0.0	7.4	152.8	21.4	16.4	29.3	10.8	14.2	10.1	21.2	21.8	21.6	25.8	7.2	25.8	31.3	7.7	12.4	26.4	92.0	32.3	80.6	13.6	8.7	30.3	9.6	3.4	625.8	47.1	4.6	13.1	14.8	11.8	80.7	13.7	19.6	97.2	47.0	16.8	318.6	20.8	4.1	33.6	48.3	167.9	9.3	38.0	30.2	85.3	22.3	14.6	11.3	268.9	60.7	51.1	37.8	9.8	16.2	33.8	195.5	666.1	5.6	6.2	13.1	11.3	16.9	39.3	26.5	20.1	14.1	8.3	18.0	14.1	24.5	31.1
MSRB1	"SelR, SelX, SepR, SEPX1"	ENSG00000198736	"Methionine sulfoxide reductase B1"	Q9NZV6	16	1938229-1943293	"Enzymes, Predicted intracellular proteins"	"Immunity, Innate immunity"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 234.2"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 275.6;monocytes: 178.7;Proximal tubular cells: 496.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"eosinophil: 1414.9;neutrophil: 3051.8"	"Lineage enriched"	"Detected in all"	7	"granulocytes: 3051.8"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008650, HPA043463, HPA069557"	Enhanced		Enhanced	Nucleoplasm		NA	NA			"Cluster 5: Granulocytes - Unknown function"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Nucleoplasm		"CAB008650: AB_1619225, HPA043463: AB_2678489, HPA069557: AB_2686153"	"unprognostic (3.93e-2)"	"unprognostic (3.68e-1)"	"unprognostic (1.32e-1)"	"unprognostic (9.61e-2)"	"unprognostic (1.76e-2)"	"unprognostic (1.15e-1)"	"unprognostic (2.19e-1)"	"unprognostic (1.49e-1)"	"unprognostic (2.88e-2)"	"unprognostic (4.90e-2)"	"unprognostic (5.29e-2)"	"unprognostic (3.60e-1)"	"unprognostic (4.27e-2)"	"unprognostic (8.46e-2)"	"unprognostic (4.92e-2)"	"unprognostic (7.31e-2)"	"unprognostic (4.59e-3)"	28.1	15.1	26.2	31.8	27.3	96.3	21.3	27.8	28.4	17.5	25.8	36.7	29.4	29.5	11.2	45.3	33.5	23.2	47.3	25.6	26.8	80.3	234.2	30.4	17.7	29.3	28.0	16.4	149.6	14.8	14.5	13.2	27.1	32.0	17.4	2.7	16.5	29.2	76.0	31.1	27.5	36.8	27.5	67.0	33.3	17.7	28.5	13.7	12.5	93.6	12.2	40.8	20.1	27.1	23.6	59.1	21.3	50.4	39.9	17.0	36.4	27.8	36.0	41.2	35.6	96.2	25.5	22.7	90.6	33.5	36.0	37.9	36.3	25.2	12.8	127.7	41.1	17.5	20.5	154.9	36.1	49.3	40.3	32.0	21.9	29.6	6.0	12.9	41.9	28.8	28.2	12.3	22.3	131.2	28.2	82.7	29.2	42.7	33.5	40.3	29.3	106.0	66.0	37.2	20.5	26.9	32.3	35.6	17.3	13.9	38.7	87.9	24.8	12.3	33.7	24.3	16.7	32.0	53.4	42.4	12.5	47.4	22.0	493.5	412.0	1414.9	31.9	194.8	32.2	28.0	26.5	26.7	171.2	28.3	20.5	22.7	3051.8	42.2	182.9	73.2	45.9	226.7	26.2	27.3	27.8	28.4	25.6	26.8	29.3	28.0	27.1	27.5	28.5	27.1	24.9	9.6	13.4	3.9	10.0	6.5	9.1	21.5	8.0	6.5	27.9	21.3	36.1	32.9	14.9	33.1	4.2	33.3	12.3	69.1	93.9	65.9	5.9	23.9	13.4	15.4	60.3	21.5	0.8	111.2	121.4	13.7	11.7	17.0	4.5	12.2	20.7	275.6	63.5	8.4	1.2	38.6	34.6	59.2	21.2	13.9	9.3	37.9	16.0	2.8	178.7	22.5	25.7	1.5	2.9	66.0	62.8	23.0	13.0	16.3	97.3	496.8	37.9	4.2	0.0	8.1	22.8	28.9	8.7	11.1	9.5	38.6	10.6	14.8	33.5	21.9
MSRB2	"CBS-1, CBS1, CGI-131, MSRB, PILB"	ENSG00000148450	"Methionine sulfoxide reductase B2"	Q9Y3D2	10	23095579-23122013	"Enzymes, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 269.1;Proximal tubular cells: 463.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA027933	Enhanced				"Intracellular and membrane"	NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 21: OE19 - Mitochondria"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA027933: AB_10601867"	"unprognostic (4.89e-2)"	"unprognostic (2.76e-2)"	"unprognostic (7.14e-3)"	"unprognostic (3.47e-3)"	"unprognostic (4.51e-1)"	"unprognostic (9.26e-3)"	"unprognostic (1.62e-1)"	"unprognostic (1.09e-1)"	"unprognostic (1.80e-1)"	"unprognostic (6.07e-3)"	"unprognostic (3.47e-2)"	"unprognostic (1.08e-2)"	"unprognostic (2.03e-1)"	"unprognostic (1.82e-2)"	"unprognostic (6.74e-2)"	"unprognostic (1.11e-1)"	"unprognostic (2.01e-1)"	16.2	17.3	29.0	6.6	30.8	7.7	11.0	29.5	40.5	13.2	26.8	22.7	9.4	15.8	16.8	10.8	17.6	7.7	61.6	29.5	32.2	19.0	31.0	9.8	3.9	30.4	30.9	11.9	5.4	23.1	14.4	8.2	30.5	14.3	11.4	13.1	9.1	19.5	42.2	5.5	11.9	16.3	29.1	9.3	11.4	3.9	30.8	8.4	14.1	51.7	4.1	17.1	11.0	29.4	7.3	10.4	19.0	11.6	19.3	17.3	5.7	11.5	6.4	7.2	8.3	7.2	15.5	5.9	10.0	24.6	10.9	4.6	6.3	8.6	5.9	40.3	7.0	4.3	17.7	4.1	27.2	0.9	5.0	22.2	14.3	8.4	2.0	15.7	10.4	11.5	5.9	10.3	16.0	21.9	7.0	5.5	10.5	41.4	6.0	8.0	10.9	1.5	9.1	2.8	3.8	26.1	14.2	12.4	23.9	15.9	8.4	17.1	7.7	6.2	5.8	14.0	6.9	13.3	4.4	0.2	8.8	12.7	5.3	0.9	1.4	2.3	0.3	1.1	0.3	0.2	0.3	0.2	0.8	0.0	0.6	0.4	3.4	0.2	0.8	1.6	0.4	0.2	29.0	30.8	29.5	40.5	29.5	32.2	30.4	30.9	30.5	29.1	30.8	29.4	29.0	0.0	16.4	27.1	11.4	18.2	52.1	33.1	59.2	68.2	69.6	79.1	269.1	80.1	21.1	90.1	22.9	116.1	10.6	86.7	176.1	130.4	1.4	49.3	71.6	34.4	55.7	30.7	9.5	63.4	61.2	70.7	23.4	46.5	29.2	114.0	42.1	195.4	109.6	112.7	16.9	54.8	26.4	70.5	25.1	4.4	49.7	54.2	72.9	11.2	29.7	126.6	7.2	14.6	26.1	90.3	79.6	62.4	24.7	34.9	80.8	463.9	24.3	57.5	59.2	52.6	71.6	4.4	7.7	66.7	17.5	69.6	13.5	60.9	71.0	54.3
MSRB3	"DFNB74, DKFZp686C1178, FLJ36866"	ENSG00000174099	"Methionine sulfoxide reductase B3"	Q8IXL7	12	65278643-65491430	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Deafness, Disease variant, Non-syndromic deafness"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enriched"	"Detected in many"	12	"Cardiomyocytes: 2801.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"eosinophil: 41.6"	"Lineage enhanced"	"Detected in many"		"granulocytes: 41.6"	"Cell line enhanced"	"Detected in many"		"fHDF/TERT166: 126.1;hTERT-RPE1: 110.6;U-937: 106.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA014432	Enhanced				"Intracellular and membrane"	NA	NA			"Cluster 2: Granulocytes - Unknown function"	"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 32: U-937 - Innate immune response"	"Cluster 43: Cardiomyocytes - Nuclear processes"			"HPA014432: AB_1854146"	"unprognostic (1.40e-2)"	"prognostic unfavorable (3.84e-4)"	"unprognostic (2.86e-3)"	"unprognostic (1.94e-1)"	"unprognostic (2.74e-2)"	"unprognostic (1.74e-2)"	"unprognostic (2.63e-2)"	"unprognostic (1.23e-1)"	"unprognostic (1.84e-2)"	"unprognostic (5.33e-2)"	"unprognostic (8.28e-2)"	"unprognostic (2.10e-1)"	"prognostic unfavorable (8.85e-8)"	"unprognostic (3.29e-3)"	"unprognostic (7.80e-2)"	"unprognostic (2.08e-2)"	"prognostic unfavorable (2.17e-4)"	44.9	10.7	12.9	20.9	13.6	21.2	26.3	12.5	12.8	29.5	18.8	108.0	11.9	85.8	20.1	63.0	41.4	33.2	90.8	11.9	18.3	10.1	3.8	30.6	5.7	15.9	15.2	16.9	5.8	3.2	6.8	25.2	13.8	52.7	27.8	12.5	10.8	103.0	104.0	9.7	25.6	123.9	14.6	13.6	36.2	5.8	18.2	4.1	14.5	69.2	3.9	60.9	23.7	11.8	8.8	19.2	16.4	75.9	71.6	63.0	0.5	87.0	92.9	33.2	19.8	0.7	1.0	0.0	18.3	126.1	10.5	1.9	7.7	22.1	30.0	0.2	15.9	0.0	16.7	0.9	46.6	47.1	0.3	33.4	11.9	28.1	39.0	110.6	68.2	0.1	0.3	0.3	76.8	2.9	0.0	11.0	5.4	0.2	10.4	0.2	22.0	0.5	7.5	1.0	0.4	7.9	30.0	1.8	21.9	16.8	14.1	44.5	78.9	42.3	22.8	19.5	34.2	8.0	6.7	0.2	11.5	106.7	26.9	15.0	0.6	41.6	0.2	0.9	0.1	0.1	0.1	0.1	0.2	0.3	0.2	0.2	6.8	8.3	0.4	10.8	0.1	1.4	12.9	13.6	12.5	12.8	11.9	18.3	15.9	15.2	13.8	14.6	18.2	11.8	55.3	12.8	3.4	76.7	0.8	6.4	16.4	11.4	4.0	22.7	2.2	45.3	2801.7	4.3	1.2	3.7	0.0	0.4	8.3	0.0	0.0	9.3	5.7	0.9	16.7	154.2	0.0	17.4	37.1	1.0	0.4	108.8	1.1	0.4	2.5	7.4	28.2	0.2	0.5	21.9	56.6	0.0	0.0	0.0	13.7	2.2	12.5	4.0	10.6	62.8	1.6	44.4	2.1	37.7	1.4	1.6	0.0	116.6	0.3	14.8	0.0	0.4	6.8	10.6	105.2	37.7	218.7	4.2	4.7	0.8	4.5	0.7	2.4	10.3	0.0	2.9
MTHFD2		ENSG00000065911	"Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase"	P13995	2	74186172-74217565	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"One-carbon metabolism"	"Hydrolase, Multifunctional enzyme, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Langerhans cells: 243.6;monocytes: 184.1;Smooth muscle cells: 239.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB003684, HPA049657"	Approved		Supported	Mitochondria	"Intracellular and membrane"	NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 52: Non-specific - Ribosome"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 48: Smooth muscle cells - ECM organization"	Mitochondria		"CAB003684: AB_425867, HPA049657: AB_2680842"	"unprognostic (1.82e-3)"	"unprognostic (4.60e-2)"	"unprognostic (8.12e-2)"	"prognostic unfavorable (2.07e-5)"	"prognostic favorable (1.01e-4)"	"unprognostic (3.10e-3)"	"unprognostic (2.24e-3)"	"unprognostic (4.75e-3)"	"unprognostic (2.64e-2)"	"unprognostic (3.96e-2)"	"unprognostic (3.76e-3)"	"unprognostic (3.57e-3)"	"prognostic unfavorable (1.11e-16)"	"unprognostic (3.66e-2)"	"unprognostic (6.52e-2)"	"unprognostic (9.07e-2)"	"unprognostic (2.34e-3)"	40.0	12.3	11.2	54.5	13.0	25.8	34.8	12.7	14.7	28.5	11.2	30.6	18.6	21.5	14.5	23.0	34.2	20.1	19.6	10.0	16.6	19.6	7.3	23.0	45.6	16.6	15.8	11.7	65.9	9.8	18.0	17.7	17.1	16.3	33.7	2.9	17.7	16.7	36.7	11.8	16.0	27.3	14.8	19.0	36.1	17.7	13.1	28.5	18.5	55.3	57.8	48.0	20.5	15.7	197.4	107.8	89.2	235.6	90.0	113.9	186.1	286.2	185.2	156.2	216.7	242.8	81.8	391.0	65.4	154.2	167.5	70.7	296.7	142.0	314.9	248.9	100.9	424.6	55.4	181.9	319.8	360.1	234.8	202.9	423.4	188.5	794.4	74.8	99.0	636.5	192.2	548.0	157.5	159.6	209.5	261.0	161.1	293.3	95.8	222.6	266.3	339.4	72.0	80.8	198.2	143.8	97.4	238.3	549.7	56.9	208.5	324.4	52.9	39.1	359.9	97.7	286.5	484.5	257.6	379.2	111.4	304.1	132.5	43.9	24.0	31.1	8.5	56.6	13.0	13.4	15.2	10.1	34.9	12.2	11.5	7.9	3.2	29.3	57.0	13.0	36.8	22.0	11.2	13.0	12.7	14.7	10.0	16.6	16.6	15.8	17.1	14.8	13.1	15.7	19.7	16.0	20.2	0.3	49.7	89.3	58.8	54.1	27.3	0.0	53.2	38.0	11.5	4.3	28.2	1.8	0.0	31.5	48.2	19.9	3.9	55.7	3.9	9.7	104.7	35.1	19.1	104.1	1.0	107.9	56.9	45.6	68.8	21.7	53.3	8.7	19.2	0.8	66.2	0.0	3.7	64.0	38.7	61.6	243.6	3.8	22.7	100.6	71.2	12.2	184.1	0.0	27.8	6.6	1.1	81.2	7.5	21.1	141.2	95.7	3.3	3.3	8.5	0.0	138.1	126.3	239.0	36.5	54.9	42.0	74.6	14.0	71.4	21.6	34.0	64.2
MTHFD2L	MGC72244	ENSG00000163738	"Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like"	Q9H903	4	74114174-74303099	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Amino-acid biosynthesis, Histidine biosynthesis, Methionine biosynthesis, One-carbon metabolism, Purine biosynthesis"	"Hydrolase, Multifunctional enzyme, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA035434	Uncertain					NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 32: Brain & Lymphoid tissue - Unknown function"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 30: Mammary glandular cells - Lactation"			"HPA035434: AB_10601038"	"unprognostic (2.01e-1)"	"unprognostic (2.19e-1)"	"unprognostic (2.03e-1)"	"unprognostic (2.32e-2)"	"unprognostic (1.52e-2)"	"unprognostic (4.09e-2)"	"unprognostic (2.67e-2)"	"unprognostic (7.73e-3)"	"unprognostic (1.42e-4)"	"unprognostic (3.45e-3)"	"unprognostic (4.23e-2)"	"unprognostic (5.07e-2)"	"unprognostic (1.44e-1)"	"unprognostic (3.16e-2)"	"unprognostic (1.19e-1)"	"unprognostic (3.00e-1)"	"unprognostic (1.81e-3)"	1.6	3.7	5.6	1.2	5.4	1.7	3.3	3.5	6.5	1.4	1.1	1.6	1.6	1.6	3.4	1.9	1.5	1.1	6.0	4.1	8.5	1.9	7.0	1.3	1.2	5.0	5.0	1.6	1.6	2.5	1.5	1.7	5.1	1.5	1.1	2.6	1.4	1.7	2.7	1.2	1.0	1.2	5.4	1.4	1.4	0.9	5.8	3.4	2.0	3.9	1.1	1.3	1.2	7.6	2.8	2.8	4.0	3.6	1.4	2.1	0.9	3.3	2.6	2.2	2.4	2.2	2.6	3.0	4.5	1.5	1.6	1.7	3.2	2.2	3.3	3.1	2.0	3.7	1.9	2.6	2.4	5.8	0.7	1.5	5.1	3.3	7.9	4.1	4.7	6.7	6.6	3.6	2.7	2.7	10.9	8.3	1.2	4.5	3.1	10.9	2.7	5.1	14.2	1.4	3.7	8.0	1.8	2.8	3.5	4.3	1.5	4.0	4.9	2.5	3.8	4.8	5.6	3.6	5.0	8.8	15.5	1.3	3.8	0.3	0.9	0.4	0.3	0.9	0.3	1.8	0.2	0.4	1.5	0.6	0.8	0.9	0.6	1.1	3.5	1.6	1.4	1.0	5.6	5.4	3.5	6.5	4.1	8.5	5.0	5.0	5.1	5.4	5.8	7.6	23.3	22.4	19.6	57.5	18.9	16.6	63.5	31.1	30.1	0.0	90.5	53.6	24.5	30.0	27.6	49.7	0.0	17.9	17.1	23.3	84.1	24.0	85.7	67.1	11.0	19.9	37.2	44.2	41.2	19.1	8.8	13.5	35.7	50.4	10.2	35.5	25.0	104.7	24.5	0.0	41.0	34.7	69.2	27.3	23.0	23.2	12.8	30.4	16.0	20.6	17.3	0.0	12.3	74.9	73.1	15.6	19.4	8.6	20.9	69.2	18.3	51.3	30.1	0.0	26.3	19.4	21.1	8.1	12.3	44.0	22.6	12.3	11.1	36.8	36.4	71.9
MTHFR		ENSG00000177000	"Methylenetetrahydrofolate reductase"	P42898	1	11785723-11806455	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		"Allosteric enzyme, Oxidoreductase"	"Disease variant, Schizophrenia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"K-562: 44.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA063389, HPA076180, HPA077255"	Enhanced		Approved	"Cell Junctions"		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 68: Epididymis - Unknown function"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 44: Endometrium - Transcription"	"Cell Junctions"		"HPA063389: AB_2685001, HPA076180: , HPA077255: "	"unprognostic (3.25e-2)"	"unprognostic (8.19e-2)"	"unprognostic (4.48e-2)"	"unprognostic (2.11e-2)"	"unprognostic (1.34e-1)"	"prognostic favorable (3.97e-5)"	"prognostic unfavorable (1.19e-4)"	"unprognostic (1.75e-2)"	"unprognostic (2.85e-1)"	"unprognostic (8.69e-2)"	"prognostic favorable (4.81e-5)"	"unprognostic (3.10e-1)"	"prognostic favorable (2.12e-4)"	"unprognostic (2.35e-3)"	"unprognostic (2.94e-1)"	"unprognostic (4.14e-2)"	"unprognostic (1.80e-2)"	12.3	11.3	7.1	10.8	10.3	28.9	10.2	12.8	8.8	9.0	5.0	11.1	10.8	8.9	53.5	10.3	12.3	10.1	23.9	10.4	6.2	12.8	13.1	16.8	12.3	9.9	7.0	19.7	11.4	6.6	17.7	7.1	9.4	10.2	8.7	12.6	6.8	6.7	17.9	13.4	14.7	10.8	5.1	18.3	14.6	10.9	8.0	7.9	16.3	16.8	12.2	10.3	7.9	8.9	2.2	9.4	10.9	12.3	10.2	15.1	2.0	5.2	14.6	6.0	5.1	8.1	13.2	18.0	3.6	7.5	16.3	4.1	8.1	7.7	2.4	9.3	6.8	13.4	13.3	3.2	13.7	7.4	16.4	13.6	6.1	8.0	6.4	10.0	10.7	17.2	44.1	11.0	6.7	3.3	8.2	3.5	3.6	9.5	3.0	8.9	6.0	20.3	8.8	11.7	10.5	17.6	8.1	7.8	10.9	6.2	12.9	11.7	8.5	6.0	4.9	7.2	1.6	6.4	9.4	32.8	7.6	16.8	5.6	0.7	2.3	1.1	2.7	4.3	0.9	1.6	0.8	1.4	1.7	2.3	1.2	1.4	2.5	2.0	6.1	0.9	0.6	1.6	7.1	10.3	12.8	8.8	10.4	6.2	9.9	7.0	9.4	5.1	8.0	8.9	15.9	25.6	48.0	8.1	18.3	8.4	6.8	11.9	15.9	0.0	17.9	10.8	37.0	11.5	13.0	27.6	0.0	5.1	6.0	44.2	1.9	8.9	18.2	32.0	25.8	16.9	12.1	29.5	15.8	25.3	3.3	21.0	52.5	55.5	8.2	10.7	37.5	23.4	22.2	0.0	15.2	18.0	6.1	39.3	39.9	42.4	18.3	32.1	12.4	16.9	26.5	0.0	20.6	9.0	13.3	21.9	20.6	9.1	10.3	10.2	36.0	17.2	12.3	0.0	19.7	22.8	23.3	6.8	5.2	15.0	9.2	2.9	10.6	21.3	18.6	9.6
MTRR	cblE	ENSG00000124275	"5-methyltetrahydrofolate-homocysteine methyltransferase reductase"	Q9UBK8	5	7851186-7906025	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Amino-acid biosynthesis, Methionine biosynthesis"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 70.1;Late spermatids: 99.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA038113	Supported		Approved	"Nucleoplasm,Intermediate filaments,Cytosol"		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 20: HeLa - Mitochondria"	"Cluster 11: Alveolar cells - Smell perception"	"Nucleoplasm, Cytosol"	"Intermediate filaments"	"HPA038113: AB_10671520"	"unprognostic (1.06e-1)"	"unprognostic (1.08e-1)"	"unprognostic (5.32e-2)"	"unprognostic (1.17e-2)"	"unprognostic (1.63e-1)"	"unprognostic (2.43e-1)"	"prognostic unfavorable (6.60e-4)"	"unprognostic (2.56e-2)"	"unprognostic (5.82e-2)"	"unprognostic (7.43e-2)"	"unprognostic (1.29e-1)"	"unprognostic (9.11e-3)"	"unprognostic (3.44e-2)"	"unprognostic (1.30e-1)"	"unprognostic (2.60e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.12e-1)"	11.2	10.6	5.1	9.5	11.2	5.7	6.3	10.1	10.9	7.2	3.4	8.3	8.9	11.7	12.3	9.3	9.6	11.8	14.4	6.5	9.0	18.7	19.4	13.1	11.1	10.9	10.4	11.4	11.9	12.8	6.7	10.8	10.6	9.0	10.1	19.2	10.5	7.1	28.9	9.1	10.2	12.0	8.2	6.7	6.7	7.1	9.3	7.5	9.0	32.9	10.6	14.4	5.5	20.0	19.3	18.1	10.2	20.0	34.0	13.6	25.1	31.1	18.5	16.5	15.4	27.8	15.1	32.6	27.9	24.6	27.4	11.8	17.0	14.2	27.9	22.9	15.8	14.6	62.0	15.3	21.9	23.4	6.8	18.3	11.4	24.6	18.4	20.4	10.4	8.0	21.9	24.2	9.8	4.2	14.2	11.7	7.3	29.4	19.0	12.4	9.5	14.1	16.2	16.0	14.0	2.5	51.6	33.7	28.6	18.1	10.7	17.5	14.6	31.9	19.7	24.1	22.7	34.7	13.5	27.3	23.1	50.5	19.1	5.3	4.0	3.0	4.1	5.5	7.0	3.3	6.5	5.7	3.6	3.3	4.1	3.6	0.1	3.1	4.4	2.3	9.1	3.3	5.1	11.2	10.1	10.9	6.5	9.0	10.9	10.4	10.6	8.2	9.3	20.0	7.7	16.0	70.1	10.1	11.1	16.3	9.4	4.6	12.0	0.0	9.7	5.1	12.9	5.7	9.0	9.2	0.0	9.9	11.4	11.0	21.5	10.2	50.1	10.0	10.7	8.0	9.6	12.4	25.4	5.5	8.9	11.8	9.2	6.7	10.2	6.5	8.6	19.3	7.7	0.0	20.8	9.1	0.0	11.1	9.4	99.2	10.5	9.7	1.8	15.0	8.1	0.0	7.2	20.1	50.9	7.2	6.0	11.7	26.5	14.3	8.7	28.9	10.1	0.0	6.6	10.7	10.1	17.4	13.1	10.5	20.6	11.2	13.8	11.8	9.4	8.7
NOS1	"nNOS, NOS"	ENSG00000089250	"Nitric oxide synthase 1"	P29475	12	117208142-117452170	"Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Calmodulin-binding, Oxidoreductase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	11	"brain: 23.0;skeletal muscle: 36.9;tongue: 57.2"	"Cell type enhanced"	"Detected in some"		"Basal prostatic cells: 10.0;Hepatic stellate cells: 18.2;Inhibitory neurons: 32.1;Oligodendrocyte precursor cells: 48.2"	"Low cancer specificity"	"Detected in some"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HaCaT: 4.6;RH-30: 9.4;RPTEC TERT1: 5.8;U-2 OS: 1.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002167, HPA058312, HPA069509"	Enhanced		Supported	"Nucleoplasm,Plasma membrane"		NA	NA				"Cluster 80: Striated muscle - Unknown function"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	"Plasma membrane"	Nucleoplasm	"CAB002167: AB_564073, HPA058312: AB_2683676, HPA069509: "	"unprognostic (1.63e-1)"	"unprognostic (3.14e-2)"	"unprognostic (2.18e-2)"	"unprognostic (6.64e-3)"	"unprognostic (4.91e-2)"	"unprognostic (2.74e-1)"	"unprognostic (2.54e-1)"	"unprognostic (9.12e-3)"	"unprognostic (2.51e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.07e-1)"	"unprognostic (7.56e-2)"	"unprognostic (1.01e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.34e-1)"	"unprognostic (5.97e-4)"	"unprognostic (1.87e-1)"	0.1	0.1	12.7	0.4	12.4	0.2	0.1	5.7	7.0	0.3	0.0	2.2	0.1	0.1	0.2	0.8	0.3	0.0	0.0	4.0	16.2	1.3	0.0	0.8	0.1	12.1	11.0	0.0	1.4	0.0	0.9	0.0	12.2	0.9	0.4	0.3	3.4	0.1	36.9	1.9	0.4	0.3	2.3	0.0	0.2	0.5	23.0	0.0	0.1	57.2	0.1	0.0	0.7	3.3	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2	0.0	0.0	4.6	0.0	0.0	0.0	0.1	0.0	0.1	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	1.1	0.0	9.4	0.0	5.8	0.0	0.2	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.7	0.0	0.0	0.1	0.0	0.0	0.2	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	12.7	12.4	5.7	7.0	4.0	16.2	12.1	11.0	12.2	2.3	23.0	3.3	0.0	0.0	0.0	1.3	0.0	3.8	10.0	2.4	4.0	0.0	0.0	0.0	1.9	0.0	0.1	0.0	0.0	0.0	0.0	0.1	1.9	0.0	3.0	5.1	0.4	3.0	0.0	0.0	2.0	0.0	0.0	0.7	0.0	8.4	0.0	0.0	18.2	0.0	0.0	0.0	32.1	0.2	0.0	0.3	0.7	0.6	0.3	0.2	1.8	1.9	0.0	0.0	0.0	48.2	5.7	0.0	0.0	0.0	0.0	4.2	0.0	0.0	0.0	0.0	0.0	1.9	0.5	0.1	1.8	0.1	0.6	0.0	0.2	0.0	0.0	1.0
NOS2	"HEP-NOS, iNOS, NOS, NOS2A"	ENSG00000007171	"Nitric oxide synthase 2"	P35228	17	27756766-27800529	"Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Calmodulin-binding, Oxidoreductase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	5	"intestine: 21.1;lymphoid tissue: 14.4"	"Cell type enhanced"	"Detected in some"		"Distal enterocytes: 40.3;Extravillous trophoblasts: 27.7;Granulosa cells: 57.3;Proximal enterocytes: 10.7;Undifferentiated cells: 10.2"	"Cancer enhanced"	"Detected in many"		"colorectal cancer: 16.0"	"Low region specificity"	"Detected in some"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	9	"CACO-2: 16.5;SCLC-21H: 13.0"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			CAB002014	Enhanced					NA	NA				"Cluster 56: Intestine - Transmembrane transport"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 53: Intestinal epithelial cells - Unknown function"			"CAB002014: "	"unprognostic (1.95e-3)"	"unprognostic (3.08e-3)"	"unprognostic (4.75e-3)"	"unprognostic (4.42e-3)"	"unprognostic (3.49e-1)"	"unprognostic (2.13e-2)"	"unprognostic (5.61e-2)"	"unprognostic (5.09e-2)"	"unprognostic (9.91e-3)"	"unprognostic (1.93e-1)"	"unprognostic (2.39e-2)"	"unprognostic (1.34e-1)"	"unprognostic (6.04e-2)"	"unprognostic (8.02e-2)"	"unprognostic (3.68e-1)"	"unprognostic (8.69e-2)"	"unprognostic (4.03e-2)"	0.9	0.5	0.2	14.4	0.5	0.0	0.3	0.1	2.1	0.3	0.0	6.8	12.1	0.2	0.0	0.7	0.4	0.4	0.4	0.7	0.2	1.6	0.1	1.8	0.8	0.3	0.1	0.6	0.3	0.1	1.3	0.6	0.5	0.6	8.9	0.2	0.1	0.2	0.8	0.2	21.1	1.8	0.1	0.1	0.1	0.3	1.0	0.1	0.4	0.7	0.1	3.6	0.2	0.9	0.0	0.1	0.1	0.0	0.0	0.0	1.2	0.0	0.0	0.0	0.0	16.5	0.0	0.0	0.0	0.0	0.1	0.0	0.6	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	1.7	0.1	0.0	0.0	0.0	0.0	0.0	0.0	13.0	0.9	0.0	0.1	0.1	0.7	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.5	0.1	2.1	0.7	0.2	0.3	0.1	0.5	0.1	1.0	0.9	1.2	0.0	0.0	1.3	0.6	0.0	0.2	3.6	0.0	0.5	0.0	0.3	0.2	0.0	0.7	0.0	0.0	0.2	0.0	40.3	0.0	0.0	0.2	0.0	0.0	0.7	2.4	0.0	4.1	0.0	27.7	0.2	0.0	0.1	0.0	57.3	0.0	0.0	0.7	0.0	2.2	3.8	2.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	1.7	0.0	4.9	0.4	0.0	1.4	10.7	0.1	0.5	0.1	0.0	0.3	1.2	0.0	1.5	0.0	0.0	0.5	0.3	0.1	10.2	1.0
NOS3	"ECNOS, eNOS"	ENSG00000164867	"Nitric oxide synthase 3"	P29474	7	150991017-151014588	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Calmodulin-binding, Oxidoreductase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 62.4"	"Cell type enhanced"	"Detected in some"		"Adipocytes: 20.4;Early spermatids: 81.9;Endothelial cells: 32.6;Hepatic stellate cells: 29.3;Late spermatids: 29.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Lineage enriched"	"Detected in single"	4	"T-cells: 2.3"	"Cell line enhanced"	"Detected in some"		"BEWO: 23.1;HUVEC TERT2: 44.7;K-562: 16.6;TIME: 82.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB002168	Enhanced					NA	NA			"Cluster 20: T-cells - T-cell receptor"	"Cluster 64: Macrophages - Immune response"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"			"CAB002168: AB_564072"	"unprognostic (6.53e-2)"	"unprognostic (3.36e-1)"	"unprognostic (1.63e-2)"	"unprognostic (8.46e-2)"	"unprognostic (2.96e-2)"	"unprognostic (1.47e-1)"	"unprognostic (1.35e-1)"	"unprognostic (1.36e-1)"	"unprognostic (6.97e-2)"	"unprognostic (2.56e-1)"	"unprognostic (9.40e-2)"	"unprognostic (2.36e-1)"	"prognostic unfavorable (3.63e-4)"	"unprognostic (1.25e-2)"	"unprognostic (6.63e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.01e-1)"	19.3	6.3	8.4	5.8	6.8	0.8	13.2	5.7	6.7	7.3	3.4	5.9	2.6	9.7	0.4	5.8	8.1	4.7	20.6	5.7	6.1	24.2	4.3	11.2	2.7	9.2	7.7	3.2	2.9	1.2	7.2	4.8	8.6	7.6	1.2	0.8	4.4	1.7	3.9	4.2	6.7	3.7	7.5	62.4	5.4	7.2	11.0	0.6	9.1	3.5	1.2	9.7	7.4	6.0	0.4	0.1	1.3	4.0	0.0	0.0	23.1	0.0	0.0	0.0	0.0	0.3	2.2	0.4	2.1	0.0	0.2	0.7	0.0	0.1	0.0	0.0	0.4	2.2	0.3	6.4	0.6	0.5	10.4	0.1	0.2	0.0	0.0	0.1	44.7	5.1	16.6	3.6	0.0	0.0	0.2	0.5	1.7	0.7	0.1	3.0	0.0	1.8	0.0	0.3	0.5	0.4	0.2	1.4	0.0	0.4	0.1	1.4	82.5	0.2	0.7	0.4	0.1	2.4	8.9	2.2	0.0	7.5	0.0	0.2	0.1	0.1	1.1	0.2	0.7	0.3	1.7	0.9	0.2	0.5	2.3	0.9	0.3	0.2	0.2	0.2	2.1	0.5	8.4	6.8	5.7	6.7	5.7	6.1	9.2	7.7	8.6	7.5	11.0	6.0	20.4	9.6	2.2	0.3	0.7	0.9	0.1	0.1	0.0	0.2	0.2	0.3	3.1	0.0	0.7	0.0	0.0	0.2	0.7	0.1	0.0	1.0	81.9	4.9	0.7	32.6	0.0	0.0	0.2	0.0	0.1	2.9	0.5	3.2	5.7	0.7	29.3	0.7	0.4	0.0	0.2	0.4	0.0	0.6	0.5	29.3	0.9	0.4	0.0	7.5	0.0	0.3	0.0	0.0	0.0	0.8	0.0	1.2	1.5	0.4	0.1	0.2	2.2	0.3	0.0	0.6	2.6	6.9	5.3	0.2	0.6	3.6	1.6	0.9	0.1	0.9
NQO1	"DHQU, DIA4, DTD, NMOR1, QR1"	ENSG00000181019	"NAD(P)H quinone dehydrogenase 1"	P15559	16	69706996-69726668	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"stomach 1: 522.7"	"Cell type enhanced"	"Detected in many"		"Gastric mucus-secreting cells: 539.8;Respiratory ciliated cells: 471.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"A549: 2434.0;OE19: 4177.0;SiHa: 2756.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA007308, CAB012421"	Enhanced		Supported	Cytosol		NA	NA		490000	"Cluster 48: NK-cells - Unknown function"	"Cluster 22: Non-specific - Unknown function"	"Cluster 21: OE19 - Mitochondria"	"Cluster 49: Ciliated cells - Cilium organization"	Cytosol		"CAB012421: , HPA007308: AB_1079501"	"unprognostic (1.04e-2)"	"unprognostic (1.95e-3)"	"unprognostic (3.14e-1)"	"unprognostic (3.76e-3)"	"unprognostic (9.03e-2)"	"prognostic unfavorable (1.45e-4)"	"unprognostic (1.05e-3)"	"unprognostic (1.97e-1)"	"unprognostic (5.07e-2)"	"unprognostic (1.24e-2)"	"unprognostic (1.49e-2)"	"unprognostic (2.25e-1)"	"unprognostic (2.41e-2)"	"unprognostic (6.36e-2)"	"unprognostic (1.45e-1)"	"unprognostic (1.98e-1)"	"unprognostic (3.27e-1)"	100.9	95.1	88.9	20.7	97.2	0.8	264.8	88.1	165.6	24.3	113.4	85.6	106.8	16.1	27.2	162.2	29.3	183.1	24.3	86.7	95.0	93.9	5.6	36.5	4.8	83.5	86.2	8.9	9.2	19.5	15.3	12.0	85.9	20.7	74.0	21.4	47.7	25.1	34.2	11.7	56.1	35.0	83.0	22.8	522.7	6.4	93.6	4.3	112.7	27.0	16.5	79.0	34.2	86.8	224.2	2434.0	203.4	901.3	473.1	682.7	77.5	363.1	632.7	363.9	547.0	302.0	1395.7	7.1	433.1	1850.6	634.3	232.1	79.1	410.3	185.2	91.3	3.3	10.9	564.4	2169.9	631.7	53.8	170.6	166.2	246.8	642.8	74.4	537.9	903.9	18.5	95.3	16.3	1914.1	725.9	11.6	98.7	107.0	4177.0	237.1	18.9	44.0	101.6	708.3	781.5	73.0	17.2	2756.6	384.8	1690.4	226.6	631.3	173.1	626.5	368.8	155.8	140.0	297.1	12.7	53.1	11.2	470.2	29.1	1864.0	1.1	3.9	0.3	6.3	0.4	3.1	5.7	7.3	8.3	3.8	2.4	2.2	5.3	0.9	18.7	0.4	1.3	15.6	5.1	88.9	97.2	88.1	165.6	86.7	95.0	83.5	86.2	85.9	83.0	93.6	86.8	88.5	25.6	14.6	8.8	2.9	5.2	26.4	185.5	32.5	10.0	31.1	30.5	4.8	138.7	90.9	42.3	4.2	1.7	3.5	165.7	146.8	25.6	0.4	117.2	11.7	81.0	20.4	1.3	1.9	147.5	4.3	32.9	539.8	65.7	19.7	10.1	28.5	2.6	15.2	3.3	1.6	81.7	107.8	3.5	7.6	1.2	25.1	10.9	17.8	4.7	128.5	10.6	7.2	0.0	5.0	75.1	59.4	12.0	2.3	22.6	62.9	44.3	471.3	15.1	6.6	21.1	72.1	0.3	1.3	128.3	4.5	1.9	5.6	17.3	51.5	40.6
NQO2	"DHQV, DIA6, NMOR2, QR2"	ENSG00000124588	"N-ribosyldihydronicotinamide:quinone reductase 2"	P16083	6	2987987-3019755	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Hepatocytes: 202.5;Proximal tubular cells: 730.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 240.2"	"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA021283, HPA021332"	Enhanced		Supported	Nucleoplasm,Cytosol		NA	NA		6000000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 16: U-266 - Nucleosome"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Cytosol	Nucleoplasm	"HPA021283: AB_1854600, HPA021332: AB_1854601"	"unprognostic (7.11e-3)"	"unprognostic (1.43e-3)"	"unprognostic (2.41e-1)"	"unprognostic (3.01e-2)"	"unprognostic (1.00e-2)"	"unprognostic (3.58e-1)"	"prognostic unfavorable (8.40e-4)"	"unprognostic (1.77e-1)"	"unprognostic (1.15e-1)"	"unprognostic (4.90e-2)"	"unprognostic (6.59e-2)"	"unprognostic (3.60e-2)"	"unprognostic (8.28e-2)"	"unprognostic (2.03e-1)"	"unprognostic (3.32e-2)"	"unprognostic (3.96e-1)"	"unprognostic (2.02e-1)"	60.0	121.5	48.1	27.0	48.8	72.1	45.0	61.1	65.4	32.6	64.3	28.2	35.3	25.8	32.9	32.8	30.0	31.5	76.5	48.5	49.6	190.3	124.2	30.4	19.5	61.8	47.9	29.8	42.6	33.5	21.2	28.6	61.4	28.1	19.6	31.1	61.9	28.9	123.6	50.7	35.6	19.8	42.9	39.3	36.1	18.2	51.5	18.3	26.8	144.9	18.2	31.8	29.0	53.2	45.7	75.7	42.1	95.3	73.0	42.9	45.4	40.5	51.2	37.1	40.9	80.0	16.1	36.9	144.7	71.1	86.4	33.7	45.4	28.5	28.9	95.9	37.1	23.6	83.0	77.3	59.7	24.4	73.9	27.8	34.2	44.9	40.9	53.4	36.8	47.9	142.3	24.1	30.8	95.5	27.0	44.4	54.9	87.6	59.8	49.3	50.1	108.2	56.6	24.0	11.4	15.9	59.5	25.9	128.9	75.0	35.4	16.9	60.7	34.8	14.4	45.9	18.1	45.4	116.7	12.3	43.3	69.5	72.7	25.2	91.8	52.8	33.1	64.2	24.4	12.1	29.6	29.8	61.7	9.1	17.8	19.6	240.2	30.0	60.8	6.5	37.2	43.2	48.1	48.8	61.1	65.4	48.5	49.6	61.8	47.9	61.4	42.9	51.5	53.2	30.3	9.6	16.1	9.8	16.3	35.2	41.5	32.7	12.5	34.8	34.2	32.1	72.8	47.1	21.3	25.8	10.4	42.6	18.2	21.2	162.4	29.1	51.6	15.1	21.4	28.0	4.8	43.8	47.0	63.4	53.9	51.5	33.1	9.0	13.9	11.0	25.7	202.5	76.6	42.1	46.7	23.3	30.5	44.7	105.7	62.8	35.8	75.4	67.6	19.7	148.6	54.0	20.6	10.6	9.1	55.8	18.3	41.0	15.0	38.6	103.7	730.3	28.7	22.5	26.3	35.0	42.9	24.8	11.4	35.4	41.2	31.2	20.8	21.9	25.4	41.8
NSDHL	"H105e3, SDR31E1, XAP104"	ENSG00000147383	"NAD(P) dependent steroid dehydrogenase-like"	Q15738	X	152830967-152869729	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Oxidoreductase	"Disease variant, Ichthyosis, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 53.0;Hepatocytes: 55.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000248, HPA000571"	Enhanced		Enhanced	"Endoplasmic reticulum,Lipid droplets"		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 37: Intestine - Unknown function"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"	"Endoplasmic reticulum"	"Lipid droplets"	"HPA000248: AB_1079507, HPA000571: AB_1079506"	"unprognostic (1.84e-1)"	"prognostic favorable (5.65e-4)"	"unprognostic (2.66e-1)"	"unprognostic (1.81e-1)"	"unprognostic (1.03e-1)"	"unprognostic (1.33e-1)"	"prognostic unfavorable (5.04e-4)"	"unprognostic (1.03e-1)"	"unprognostic (5.70e-2)"	"unprognostic (4.32e-2)"	"unprognostic (5.62e-2)"	"unprognostic (2.63e-1)"	"prognostic favorable (6.09e-5)"	"unprognostic (3.53e-2)"	"unprognostic (1.36e-1)"	"unprognostic (3.91e-2)"	"unprognostic (4.79e-2)"	24.0	38.8	13.2	10.2	12.6	8.9	20.2	14.2	13.3	20.3	13.7	13.9	17.6	13.6	44.5	51.7	14.9	7.9	22.4	13.7	14.3	14.9	50.4	12.9	9.1	16.8	15.4	10.3	10.6	12.9	8.8	10.3	18.5	14.8	13.5	10.4	16.7	21.3	10.1	22.6	24.2	12.5	13.4	9.5	13.8	8.9	15.2	9.9	13.3	10.9	18.1	12.1	24.1	15.1	135.6	48.9	65.5	33.8	54.9	41.5	36.2	26.3	35.2	46.9	59.3	68.5	71.7	67.0	86.0	35.9	174.2	67.6	85.5	122.1	41.3	22.0	49.5	27.9	44.7	70.3	39.8	27.6	21.1	51.1	46.3	92.2	23.0	20.2	44.2	28.7	46.4	29.1	36.1	60.1	27.3	35.8	26.0	67.4	58.1	19.9	47.4	54.6	98.9	55.7	23.4	26.5	23.4	34.6	28.4	44.9	23.1	35.0	38.7	21.6	35.4	52.3	51.0	40.9	29.4	114.9	40.0	42.4	20.8	21.0	19.6	18.7	16.3	18.7	16.4	19.1	16.1	14.1	19.4	15.1	11.6	12.7	2.2	19.7	14.2	17.4	20.4	15.2	13.2	12.6	14.2	13.3	13.7	14.3	16.8	15.4	18.5	13.4	15.2	15.1	7.1	12.8	16.7	5.9	6.3	10.8	12.8	53.0	10.8	4.3	11.7	6.1	25.0	15.7	29.0	12.9	0.0	21.5	6.1	9.6	9.8	20.1	13.3	15.5	6.6	9.2	6.0	13.0	2.2	20.3	22.0	9.0	8.2	15.5	8.2	14.0	7.5	55.0	18.6	1.7	2.2	10.2	26.4	8.7	9.6	8.0	8.4	7.9	5.4	1.0	11.0	10.6	7.2	2.5	5.7	21.4	11.9	9.1	11.3	10.4	25.2	16.5	25.4	6.2	0.0	5.9	12.5	3.7	7.8	19.4	12.1	18.6	5.3	25.1	11.2	16.4
NXN	"FLJ12614, NRX"	ENSG00000167693	Nucleoredoxin	Q6DKJ4	17	799310-979776	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Differentiation, Wnt signaling pathway"	"Developmental protein, Oxidoreductase"	"Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 99.2"	"Cell type enhanced"	"Detected in many"		"Late spermatids: 91.5;Microglial cells: 87.1;Urothelial cells: 59.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"HaCaT: 100.7;HHSteC: 106.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA023566	Approved		Approved	Cytosol		NA	NA			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 59: Non-specific - Translation"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 25: Spermatids - Spermatogenesis"	Cytosol		"HPA023566: AB_1854737"	"unprognostic (1.68e-2)"	"unprognostic (1.75e-1)"	"unprognostic (1.15e-2)"	"unprognostic (3.48e-2)"	"unprognostic (7.29e-2)"	"unprognostic (1.00e-1)"	"unprognostic (1.75e-2)"	"unprognostic (6.98e-2)"	"unprognostic (1.65e-3)"	"unprognostic (2.27e-2)"	"unprognostic (3.16e-2)"	"unprognostic (1.43e-1)"	"unprognostic (5.76e-2)"	"unprognostic (3.56e-2)"	"unprognostic (2.34e-1)"	"unprognostic (2.68e-2)"	"unprognostic (2.05e-3)"	16.9	7.5	14.5	8.7	13.1	1.1	19.0	12.1	15.0	41.3	21.9	70.0	5.4	47.2	11.6	27.2	29.1	13.7	16.0	13.5	13.2	14.4	9.5	24.6	5.0	13.6	14.9	14.8	33.6	2.6	6.8	14.5	14.0	39.7	4.6	8.9	20.7	25.0	99.2	24.9	19.8	23.1	12.8	6.4	28.3	9.6	17.1	13.1	12.9	35.7	13.8	43.4	42.5	12.3	14.3	21.2	81.5	52.8	5.3	1.1	4.5	44.6	29.3	46.1	73.3	50.4	14.8	0.6	83.6	57.5	10.8	100.7	52.9	83.2	36.3	0.6	30.9	0.2	12.7	44.8	106.1	0.3	2.3	32.2	75.6	6.0	36.0	9.3	41.9	11.3	7.4	0.0	12.3	5.8	2.9	1.0	39.2	42.3	1.4	6.2	2.1	0.3	32.9	20.6	20.9	13.6	21.1	0.1	1.1	50.3	14.9	13.0	0.0	1.0	19.1	0.4	12.5	7.5	5.2	0.4	0.4	1.7	0.7	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2	0.0	0.2	0.0	0.2	0.2	0.0	0.2	0.2	0.0	14.5	13.1	12.1	15.0	13.5	13.2	13.6	14.9	14.0	12.8	17.1	12.3	36.5	32.1	11.7	13.4	0.9	17.5	53.6	18.8	12.0	2.6	7.6	12.4	8.6	2.8	13.2	3.7	33.3	0.4	0.4	0.1	0.0	3.5	25.1	20.2	52.1	34.7	1.8	2.7	6.9	24.6	0.7	23.0	1.1	12.6	1.3	1.0	14.6	8.2	6.3	5.0	10.7	0.0	0.0	0.3	8.8	91.5	15.5	1.9	7.2	87.1	0.6	11.4	0.0	23.1	3.3	5.9	0.0	7.2	0.4	36.0	0.0	0.5	15.5	18.0	13.1	14.5	19.2	13.1	10.1	13.1	12.4	0.4	1.5	27.2	0.0	59.0
OGDH	"E1k, KGD1, OGDC-E1, OGDH2"	ENSG00000105953	"Oxoglutarate dehydrogenase"	Q02218	7	44606572-44709066	"Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	Glycolysis	Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 324.0;skeletal muscle: 363.6;tongue: 374.7"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 114.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019514, HPA020347"	Supported		Enhanced	Mitochondria		No	No		130000	"Cluster 39: Non-specific - mRNA processing"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 54: Cardiomyocytes - Muscle contraction"	Mitochondria		"HPA019514: AB_1854772, HPA020347: AB_1854773"	"unprognostic (1.96e-2)"	"unprognostic (1.40e-1)"	"unprognostic (4.39e-1)"	"unprognostic (5.64e-3)"	"unprognostic (3.02e-3)"	"unprognostic (1.20e-1)"	"unprognostic (3.45e-1)"	"unprognostic (7.58e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.52e-2)"	"unprognostic (3.38e-1)"	"unprognostic (3.30e-2)"	"prognostic favorable (2.22e-14)"	"unprognostic (1.53e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.23e-2)"	"unprognostic (5.88e-3)"	64.9	67.4	35.0	39.2	39.4	32.1	32.0	42.8	45.4	33.8	119.6	56.3	95.6	40.9	16.6	61.6	34.0	26.9	324.0	34.4	50.6	89.7	39.8	43.4	40.0	44.6	44.4	24.8	27.5	99.9	34.9	33.1	44.2	37.9	41.5	25.9	43.0	46.9	363.6	56.4	87.5	51.0	35.7	39.0	52.5	36.2	43.6	32.1	54.9	374.7	41.5	42.5	37.7	35.6	35.8	73.5	42.2	66.0	63.4	69.8	41.9	54.2	51.3	59.5	50.9	67.2	71.7	156.0	63.0	79.2	119.2	108.2	85.7	81.4	58.4	92.0	22.8	47.4	140.6	33.5	32.8	59.4	51.2	66.0	60.5	85.4	60.9	43.0	82.4	50.7	55.8	45.4	63.7	50.1	59.2	34.1	39.8	97.7	81.8	55.9	30.1	175.9	68.5	104.4	73.2	35.0	78.8	107.6	34.4	75.8	64.2	58.7	66.4	43.4	38.5	76.3	64.0	40.9	84.0	85.9	78.4	65.7	80.4	9.9	21.8	12.6	17.9	28.5	19.5	11.1	20.7	18.1	22.0	9.3	8.5	10.8	12.2	19.3	35.4	10.8	42.1	23.2	35.0	39.4	42.8	45.4	34.4	50.6	44.6	44.4	44.2	35.7	43.6	35.6	19.6	6.4	22.5	49.3	23.1	19.5	12.3	15.9	22.8	21.4	14.4	18.2	114.3	12.8	14.2	47.8	18.8	24.0	20.0	64.5	31.3	14.9	51.0	26.1	15.6	16.0	23.4	32.0	43.3	16.9	16.4	20.6	35.2	38.9	21.5	15.5	17.9	22.6	33.8	62.2	53.1	32.6	12.2	24.5	43.4	24.5	11.8	33.8	21.4	29.0	22.7	14.3	16.5	22.1	36.6	20.9	38.0	17.3	27.8	16.4	82.0	51.8	17.0	24.0	19.7	24.7	20.2	10.6	19.9	28.1	26.3	36.7	27.7	30.3	33.5	18.1
OGDHL	FLJ10851	ENSG00000197444	"Oxoglutarate dehydrogenase L"	Q9ULD0	10	49734641-49762379	"Citric acid cycle related proteins, Enzymes, Metabolic proteins, Predicted intracellular proteins"	Glycolysis	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"choroid plexus: 98.5;kidney: 121.8;liver: 80.0"	"Cell type enhanced"	"Detected in some"		"Bipolar cells: 30.4;Collecting duct cells: 29.5;Cone photoreceptor cells: 31.3;Distal tubular cells: 92.0;Hepatocytes: 55.3;Horizontal cells: 30.3;Proximal tubular cells: 84.7"	"Group enriched"	"Detected in many"	5	"liver cancer: 14.7;renal cancer: 44.9"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"AN3-CA: 21.3;RPTEC TERT1: 43.4;SH-SY5Y: 16.3;SK-BR-3: 16.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA043716, HPA052497"	Enhanced		Approved	"Nucleoli fibrillar center"		NA	NA				"Cluster 88: Choroid plexus - Transmembrane transport"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	"Nucleoli fibrillar center"		"HPA043716: , HPA052497: AB_2681853"	"unprognostic (9.05e-2)"	"unprognostic (3.93e-3)"	"unprognostic (5.30e-2)"	"unprognostic (2.50e-1)"	"unprognostic (3.70e-3)"	"unprognostic (2.03e-1)"	"unprognostic (1.46e-3)"	"unprognostic (4.19e-1)"	"unprognostic (2.07e-1)"	"unprognostic (1.46e-2)"	"unprognostic (1.52e-3)"	"unprognostic (4.60e-1)"	"prognostic favorable (1.21e-14)"	"unprognostic (3.25e-2)"	"unprognostic (1.85e-1)"	"unprognostic (1.59e-3)"	"unprognostic (8.38e-2)"	0.2	11.6	23.1	0.3	23.4	0.0	0.0	23.7	41.1	0.7	98.5	1.4	1.0	2.2	0.5	0.1	1.0	0.4	5.8	24.4	36.9	121.8	80.0	0.0	0.2	38.4	25.6	1.6	4.3	50.5	29.3	0.1	38.9	1.6	0.3	18.7	17.1	6.3	0.1	0.1	1.1	0.7	15.4	0.3	1.0	2.3	33.8	0.5	23.0	0.8	0.6	0.5	0.5	24.3	0.0	0.0	4.7	21.3	0.0	0.0	2.7	0.1	0.1	1.1	0.2	10.5	2.3	0.0	11.4	0.0	3.4	0.4	7.4	0.2	0.4	0.0	0.4	0.0	0.2	5.3	0.2	0.0	1.6	0.3	0.0	0.0	0.0	0.6	0.0	5.4	0.5	0.0	0.0	3.2	8.2	7.3	2.0	0.8	1.0	0.0	0.0	0.0	43.4	0.7	12.0	16.3	0.1	16.2	1.1	6.1	4.5	2.9	0.0	0.0	10.6	0.0	0.7	0.2	0.1	0.0	0.0	2.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	23.1	23.4	23.7	41.1	24.4	36.9	38.4	25.6	38.9	15.4	33.8	24.3	0.0	0.0	0.0	20.2	0.8	0.0	0.9	0.4	0.0	30.4	0.1	0.1	4.4	2.8	0.1	29.5	31.3	0.0	0.0	0.4	92.0	1.1	0.2	0.9	0.2	0.3	4.8	0.0	16.8	0.0	0.1	0.3	0.0	1.6	0.0	0.7	1.4	55.3	0.1	30.3	21.4	0.5	2.0	1.3	0.0	0.5	0.0	0.5	0.0	1.0	0.0	5.4	0.0	3.5	1.8	0.1	1.1	0.0	0.0	0.3	0.0	84.7	0.0	18.1	0.0	0.0	0.2	0.1	2.4	0.0	0.0	0.1	0.6	0.4	0.3	0.3
P3H1	"GROS1, LEPRE1, LEPRECAN, MGC117314"	ENSG00000117385	"Prolyl 3-hydroxylase 1"	Q32P28	1	42746335-42767084	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"	"Dwarfism, Osteogenesis imperfecta"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 47.9;Extravillous trophoblasts: 56.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"fHDF/TERT166: 193.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA012113, HPA016980"	Approved		Approved	Nucleoli,Vesicles	"Intracellular and membrane"	NA	NA		18000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 28: Placenta - Pregnancy"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 33: Fibroblasts - ECM organization"	Vesicles	Nucleoli	"HPA012113: AB_2668626, HPA016980: AB_2669498"	"unprognostic (3.24e-1)"	"unprognostic (1.04e-1)"	"unprognostic (9.37e-2)"	"unprognostic (4.57e-1)"	"unprognostic (2.03e-1)"	"unprognostic (1.19e-1)"	"prognostic unfavorable (4.95e-7)"	"unprognostic (5.41e-2)"	"unprognostic (2.70e-3)"	"unprognostic (9.16e-2)"	"unprognostic (2.21e-1)"	"unprognostic (1.21e-1)"	"prognostic unfavorable (0.00e+0)"	"unprognostic (1.41e-2)"	"unprognostic (1.23e-1)"	"unprognostic (2.67e-2)"	"unprognostic (1.60e-3)"	12.4	11.1	3.6	8.7	3.5	6.1	10.2	3.6	4.4	13.4	7.3	8.3	2.4	13.8	6.1	4.4	9.8	12.0	9.1	3.8	3.8	7.2	13.3	11.6	5.1	5.2	3.5	12.8	6.8	5.9	15.5	37.4	3.8	7.5	5.4	1.3	6.7	5.9	3.0	7.6	7.4	20.3	3.4	11.5	6.7	15.2	3.8	7.6	7.6	3.9	5.1	12.3	8.5	3.6	8.7	22.3	48.7	115.0	112.8	85.4	20.1	101.8	131.9	71.9	121.7	11.3	18.8	13.0	79.7	193.0	29.2	7.8	20.9	25.9	49.2	19.5	26.3	30.5	32.2	32.6	65.2	30.9	34.0	73.8	17.4	72.6	30.9	102.4	102.9	18.3	17.5	16.1	49.0	4.7	20.6	17.8	53.1	4.7	16.0	19.9	71.9	17.7	38.2	4.9	10.2	17.3	62.5	1.7	45.8	85.2	3.7	127.0	85.1	53.8	47.2	43.4	41.2	14.5	17.5	11.9	61.5	41.5	77.0	5.0	18.9	16.8	8.3	20.4	8.8	4.1	6.3	7.0	23.6	3.3	5.1	5.3	1.8	17.8	26.3	10.9	12.4	9.3	3.6	3.5	3.6	4.4	3.8	3.8	5.2	3.5	3.8	3.4	3.8	3.6	13.7	3.2	2.3	5.9	10.5	0.0	6.4	0.0	6.2	10.2	4.5	6.5	5.0	7.2	0.6	11.0	25.0	47.9	11.1	0.4	0.0	11.5	17.1	3.2	30.1	16.4	6.1	11.3	12.9	7.6	56.6	34.4	3.6	4.4	1.3	28.8	16.8	11.3	17.6	15.2	10.8	2.5	0.0	8.7	0.0	10.8	19.3	11.7	0.0	9.4	10.5	3.5	6.2	9.5	6.9	7.4	2.0	16.1	11.2	3.4	1.7	1.9	0.7	22.1	0.0	17.2	22.3	30.6	18.8	3.5	0.0	17.5	9.6	27.0	1.9	4.5
P3H2	"FLJ10718, LEPREL1, MLAT4"	ENSG00000090530	"Prolyl 3-hydroxylase 2"	Q8IVL5	3	189956728-190122437	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 80.3;Granulosa cells: 124.1;Microglial cells: 91.8;Theca cells: 74.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in some"	22	"plasmacytoid DC: 28.9"	"Lineage enriched"	"Detected in single"	90	"dendritic cells: 28.9"	"Cell line enhanced"	"Detected in many"		"GAMG: 120.2;HaCaT: 109.9;RPTEC TERT1: 109.8"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA007890, HPA013355, HPA013611"	Approved		Supported	"Nucleoplasm,Golgi apparatus,Vesicles,Cytosol"	"Intracellular and membrane"	NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 64: Macrophages - Immune response"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 40: Granulosa cells - Unknown function"	"Golgi apparatus"	"Nucleoplasm, Vesicles, Cytosol"	"HPA007890: AB_1852796, HPA013355: AB_1852798, HPA013611: "	"unprognostic (4.90e-2)"	"unprognostic (1.57e-1)"	"unprognostic (3.76e-1)"	"unprognostic (4.32e-3)"	"unprognostic (1.97e-2)"	"unprognostic (7.75e-2)"	"unprognostic (9.68e-2)"	"unprognostic (2.17e-1)"	"unprognostic (3.15e-1)"	"unprognostic (1.19e-1)"	"unprognostic (1.03e-3)"	"unprognostic (1.60e-1)"	"unprognostic (1.15e-2)"	"unprognostic (1.80e-2)"	"unprognostic (1.48e-1)"	"unprognostic (1.10e-1)"	"unprognostic (4.01e-2)"	4.9	41.6	2.8	4.9	3.1	1.0	6.5	3.0	3.1	17.0	1.8	24.0	2.7	17.6	18.5	11.0	8.0	4.8	8.8	3.3	4.8	51.3	7.0	28.7	2.4	7.6	4.7	16.1	3.6	2.3	8.2	9.2	6.7	37.6	10.4	19.3	4.9	26.5	1.2	17.8	6.7	32.4	5.2	54.8	23.9	4.2	4.9	5.2	3.0	1.7	2.0	11.9	19.9	8.3	46.9	18.2	35.1	0.2	0.6	1.4	42.1	48.7	19.3	7.8	12.6	15.0	18.0	0.1	27.1	8.6	120.2	109.9	0.1	65.3	16.3	0.4	6.2	0.1	12.1	0.3	35.4	0.2	0.3	16.9	21.4	15.2	5.4	73.5	1.4	0.1	0.1	0.4	12.3	1.1	0.1	0.4	11.0	31.3	3.7	0.1	7.1	2.8	109.8	77.5	2.5	0.3	66.1	3.7	29.3	51.1	0.1	0.7	24.4	45.9	16.8	0.4	8.9	3.4	0.2	0.5	10.6	0.2	60.2	0.3	0.2	0.1	0.0	0.1	0.0	0.1	0.0	0.0	1.2	0.0	0.0	0.0	0.2	0.1	0.0	28.9	0.0	0.2	2.8	3.1	3.0	3.1	3.3	4.8	7.6	4.7	6.7	5.2	4.9	8.3	5.7	48.1	80.3	19.2	1.0	0.0	7.7	0.0	13.6	2.3	1.6	9.9	1.0	2.8	3.1	44.1	4.2	42.0	9.5	19.8	5.9	4.7	19.6	2.0	27.3	10.5	0.0	2.7	55.6	0.8	14.7	10.3	8.6	1.5	1.3	124.1	32.5	0.8	11.4	10.1	60.4	0.5	0.0	3.2	0.0	14.9	4.7	5.6	0.0	91.8	0.8	44.5	0.0	43.7	4.4	30.6	1.9	0.0	0.2	15.1	0.0	26.2	0.0	1.2	0.0	10.9	45.2	0.5	0.9	13.5	0.0	38.6	0.7	74.3	2.1	3.9
P3H3	"GRCB, HSU47926, LEPREL2"	ENSG00000110811	"Prolyl 3-hydroxylase 3"	Q8IVL6	12	6828407-6839847	"Enzymes, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"endometrium 1: 19.2"	"Cell type enhanced"	"Detected in many"		"Bipolar cells: 47.2;Cone photoreceptor cells: 100.1;Horizontal cells: 43.7;Leydig cells: 49.7;Peritubular cells: 38.4;Rod photoreceptor cells: 28.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BJ: 39.6;hTERT-RPE1: 27.3;NTERA-2: 27.5;U-251 MG: 27.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA043695	Approved		Approved	"Nucleoli,Plasma membrane,Cytosol"	"Intracellular and membrane"	NA	NA		740000		"Cluster 89: Fibroblasts - ECM organization"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 9: Photoreceptor cells - Phototransduction"	"Plasma membrane, Cytosol"	Nucleoli	"HPA043695: AB_10797146"	"unprognostic (2.54e-1)"	"unprognostic (6.66e-2)"	"unprognostic (1.14e-1)"	"unprognostic (3.34e-2)"	"unprognostic (5.76e-2)"	"unprognostic (6.55e-2)"	"unprognostic (2.66e-1)"	"unprognostic (2.92e-1)"	"unprognostic (6.90e-2)"	"unprognostic (1.44e-1)"	"prognostic favorable (4.91e-4)"	"unprognostic (1.29e-1)"	"prognostic unfavorable (1.64e-4)"	"unprognostic (2.58e-2)"	"unprognostic (9.67e-2)"	"unprognostic (2.27e-1)"	"unprognostic (7.77e-3)"	3.5	2.6	1.2	1.5	0.7	0.3	3.9	3.7	2.7	11.9	5.6	5.4	0.8	19.2	0.5	1.6	9.9	1.7	4.5	1.1	1.2	2.0	0.6	3.7	0.3	1.3	0.2	12.4	2.9	4.5	15.4	1.3	0.3	6.0	0.3	4.1	6.5	3.7	0.8	3.0	2.8	3.8	0.2	1.3	3.8	1.2	0.9	0.1	4.3	0.3	0.3	7.8	6.4	0.5	0.0	1.6	7.1	14.0	8.4	10.2	0.3	39.6	22.4	12.2	13.5	0.6	0.0	0.0	0.5	14.9	0.5	0.0	4.4	0.4	2.7	0.1	18.8	1.0	4.2	1.9	5.9	1.0	0.0	11.1	0.4	6.0	3.3	27.3	13.1	1.2	3.7	0.0	5.7	0.0	0.1	0.4	27.5	0.0	1.1	0.0	6.9	0.2	0.6	0.0	2.8	10.5	0.1	0.0	4.8	3.4	0.2	0.2	23.2	12.0	17.5	18.6	27.7	0.1	0.3	0.3	10.2	0.0	4.9	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.1	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.7	3.7	2.7	1.1	1.2	1.3	0.2	0.3	0.2	0.9	0.5	2.3	0.0	0.0	3.3	0.5	0.0	4.9	0.0	2.2	47.2	5.3	5.5	11.1	1.5	1.8	5.5	100.1	0.5	0.1	0.1	1.9	1.4	0.9	0.9	19.6	3.9	1.2	0.0	13.1	2.7	0.5	24.1	2.0	0.4	0.0	0.8	7.9	0.0	1.4	43.7	13.7	2.7	0.0	0.0	0.0	2.2	49.7	0.5	0.0	2.8	1.1	5.3	0.0	5.5	1.3	1.3	0.1	38.4	3.1	5.1	0.4	0.4	1.5	28.8	6.6	7.8	11.9	0.7	0.8	0.8	0.0	1.0	0.9	3.2	0.6	1.5
P4HA1	"C-P4Halpha(I), P4HA"	ENSG00000122884	"Prolyl 4-hydroxylase subunit alpha 1"	P13674	10	73007217-73096974	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"hTERT-RPE1: 494.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA007599, HPA026593"	Enhanced		Supported	"Endoplasmic reticulum,Vesicles,Mitochondria"	"Intracellular and membrane"	Yes	No		60000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"	"Endoplasmic reticulum"	"Vesicles, Mitochondria"	"HPA007599: AB_1854891, HPA026593: AB_1854892"	"prognostic unfavorable (9.01e-4)"	"prognostic unfavorable (3.19e-5)"	"unprognostic (2.76e-3)"	"unprognostic (3.04e-1)"	"unprognostic (1.69e-2)"	"prognostic unfavorable (1.19e-5)"	"unprognostic (2.30e-1)"	"prognostic unfavorable (5.10e-4)"	"unprognostic (1.28e-1)"	"unprognostic (2.29e-1)"	"prognostic unfavorable (2.85e-4)"	"unprognostic (9.15e-2)"	"prognostic unfavorable (9.40e-9)"	"unprognostic (3.14e-1)"	"unprognostic (4.22e-2)"	"unprognostic (1.02e-2)"	"unprognostic (5.75e-2)"	28.1	26.0	25.7	20.8	26.4	15.5	26.3	29.6	58.5	31.9	34.7	16.3	11.0	27.0	18.9	10.1	41.1	26.3	38.7	26.5	27.1	35.8	72.8	27.8	16.2	32.9	30.0	34.9	17.5	17.0	11.6	65.3	33.0	20.0	17.4	33.3	13.0	18.4	110.9	17.4	14.4	28.5	30.2	19.6	19.8	19.3	30.1	12.9	13.9	54.0	14.6	29.6	18.2	39.0	84.0	21.2	60.1	117.6	181.2	138.3	50.1	239.9	215.8	90.8	215.8	35.6	63.6	28.4	89.7	239.0	55.1	92.5	38.3	87.7	197.1	36.5	14.5	24.4	18.6	42.5	75.3	45.1	16.4	84.5	50.3	77.7	101.6	494.2	43.5	23.8	38.3	14.7	79.3	22.4	17.9	42.9	21.6	38.9	92.3	16.4	40.2	52.4	51.0	35.6	5.5	33.7	49.2	143.2	58.3	135.0	21.9	41.9	41.9	110.5	44.8	31.3	56.9	81.8	31.3	13.7	198.1	64.5	54.9	1.1	18.8	14.9	6.7	23.5	8.7	8.2	8.1	7.9	20.7	9.2	5.9	6.1	10.4	5.2	25.7	16.6	10.7	9.1	25.7	26.4	29.6	58.5	26.5	27.1	32.9	30.0	33.0	30.2	30.1	39.0	29.0	6.4	28.4	87.1	31.7	36.3	33.0	138.0	22.2	13.5	23.8	15.7	42.0	7.2	69.2	23.9	27.1	31.5	24.9	25.1	0.0	33.1	16.8	85.6	89.2	25.9	10.3	7.2	48.8	19.5	116.4	67.7	14.3	131.4	40.5	16.9	20.0	29.8	43.9	11.8	41.6	9.5	46.8	54.1	75.7	8.1	51.9	51.5	44.4	62.8	39.0	34.0	6.2	86.5	44.8	36.6	27.1	47.0	32.9	24.9	13.5	25.1	94.6	17.2	39.5	37.0	44.7	61.7	34.0	9.8	23.9	33.2	27.7	31.1	7.0	17.6
P4HA2	C-P4Halpha(II)	ENSG00000072682	"Prolyl 4-hydroxylase subunit alpha 2"	O15460	5	132190147-132295315	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 115.6;Endometrial stromal cells: 96.9;Skeletal myocytes: 109.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in many"		"HHSteC: 324.2;U-87 MG: 323.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA016997, HPA027824, CAB062557"	Enhanced		Enhanced	"Endoplasmic reticulum,Vesicles"	"Intracellular and membrane"	No	No		13000	"Cluster 1: Neutrophils - Mixed function"	"Cluster 7: Kidney - Transmembrane transport"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"	"Endoplasmic reticulum, Vesicles"		"CAB062557: AB_2665641, HPA016997: AB_2669501, HPA027824: AB_2672402"	"unprognostic (1.30e-3)"	"prognostic unfavorable (1.24e-5)"	"unprognostic (2.56e-3)"	"unprognostic (1.28e-3)"	"unprognostic (2.08e-3)"	"unprognostic (1.62e-3)"	"unprognostic (1.16e-3)"	"unprognostic (1.93e-3)"	"unprognostic (2.83e-2)"	"unprognostic (1.92e-1)"	"unprognostic (8.98e-2)"	"unprognostic (1.91e-1)"	"prognostic unfavorable (2.77e-7)"	"unprognostic (2.50e-2)"	"unprognostic (1.61e-1)"	"unprognostic (2.23e-1)"	"prognostic unfavorable (3.12e-4)"	17.4	11.7	11.9	16.1	12.1	2.4	12.3	11.4	28.4	29.5	42.2	28.7	22.6	31.1	76.7	19.6	29.6	19.9	40.6	14.4	17.2	80.0	10.5	31.5	2.5	11.4	14.3	8.6	70.7	10.9	19.9	35.1	19.1	10.8	32.7	7.8	32.5	17.1	13.0	16.7	26.8	52.6	10.0	8.7	20.5	9.7	16.8	11.3	20.7	22.9	8.3	22.9	22.3	12.2	57.0	34.9	11.2	57.2	149.2	173.7	61.1	261.9	223.7	108.9	265.0	78.9	50.3	1.5	71.8	283.3	120.5	70.2	33.2	136.5	172.7	41.5	11.9	0.6	48.1	49.0	324.2	0.0	33.9	104.6	193.1	128.8	117.4	162.7	59.1	0.1	21.2	3.6	134.0	23.2	0.2	0.5	3.0	53.7	27.2	0.9	3.6	9.8	31.1	11.0	5.4	15.8	67.7	22.3	47.9	84.1	28.4	3.7	88.9	171.7	63.5	51.0	57.1	24.4	28.1	11.8	323.4	0.4	48.3	0.0	0.4	0.0	0.8	0.3	0.7	0.0	0.4	0.1	0.2	0.0	0.0	0.1	1.0	0.9	0.0	0.3	0.0	0.2	11.9	12.1	11.4	28.4	14.4	17.2	11.4	14.3	19.1	10.0	16.8	12.2	13.0	35.3	10.3	7.5	1.1	16.8	43.6	115.6	23.9	11.6	9.5	9.5	13.3	8.6	36.9	11.0	22.9	2.6	0.3	43.2	5.9	68.3	1.4	26.7	96.9	12.2	15.0	0.0	7.7	71.8	70.2	61.6	12.8	28.0	5.7	11.1	9.3	7.8	7.6	0.0	7.7	18.6	32.6	1.3	5.5	2.0	8.1	4.4	30.2	2.8	2.6	6.8	0.0	1.5	1.2	81.9	41.0	5.3	3.0	19.6	41.4	44.6	71.9	5.2	26.3	109.4	47.6	23.0	29.1	6.8	9.8	7.5	4.8	10.4	13.8	15.3
P4HA3	C-P4Halpha(III)	ENSG00000149380	"Prolyl 4-hydroxylase subunit alpha 3"	Q7Z4N8	11	74235801-74311640	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"smooth muscle: 10.5"	"Cell type enhanced"	"Detected in many"		"Cone photoreceptor cells: 14.6;Early spermatids: 25.6;Erythroid cells: 13.5;Horizontal cells: 18.5;Rod photoreceptor cells: 12.8;Spermatocytes: 13.1;Spermatogonia: 12.2"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"BJ: 19.5;fHDF/TERT166: 9.5;HSkMC: 9.1;HUVEC TERT2: 38.2;TIME: 27.4"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in single"			HPA007897	Approved				"Intracellular and membrane"	NA	NA				"Cluster 46: Fibroblasts - ECM organization"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 23: Spermatids - Flagellum & Golgi organization"			"HPA007897: AB_2156427"	"unprognostic (2.74e-2)"	"unprognostic (1.37e-4)"	"unprognostic (1.31e-3)"	"unprognostic (3.19e-2)"	"unprognostic (2.54e-4)"	"unprognostic (9.65e-3)"	"unprognostic (4.34e-2)"	"unprognostic (3.89e-2)"	"unprognostic (2.02e-1)"	"unprognostic (4.21e-3)"	"unprognostic (1.38e-2)"	"unprognostic (8.31e-2)"	"prognostic unfavorable (3.34e-9)"	"unprognostic (1.96e-3)"	"unprognostic (9.29e-2)"	"unprognostic (1.05e-2)"	"prognostic unfavorable (7.83e-4)"	1.6	0.7	0.1	3.9	0.0	0.0	0.9	0.1	0.3	1.3	0.3	1.6	0.3	4.5	0.5	0.3	1.2	5.6	0.3	0.0	0.1	1.0	1.3	1.4	0.9	0.1	0.1	1.0	0.2	0.0	3.7	3.9	0.1	6.3	0.7	0.0	0.5	4.3	0.1	0.3	0.4	10.5	0.0	0.1	0.4	1.5	0.1	0.1	2.6	0.1	0.3	5.4	1.7	0.1	0.0	1.4	1.7	0.0	6.2	0.7	0.0	19.5	1.4	1.0	2.1	0.0	0.0	0.0	1.8	9.5	0.7	0.0	0.0	0.3	0.2	0.0	0.1	0.0	1.2	0.0	8.0	0.0	0.0	9.1	0.0	6.5	0.7	1.1	38.2	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	2.1	0.0	0.1	0.0	0.0	0.0	27.4	0.1	1.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.3	0.0	0.1	0.1	0.1	0.1	0.0	0.1	0.1	1.0	0.0	0.0	0.0	0.2	0.4	0.7	0.9	0.0	9.1	0.5	0.1	0.4	0.0	0.2	0.0	14.6	0.2	3.1	0.2	0.0	0.2	25.6	3.8	2.5	3.2	0.0	13.5	2.4	0.0	0.4	5.2	0.0	1.0	0.0	4.3	6.1	0.0	0.4	18.5	3.3	0.2	0.0	0.9	1.1	3.2	0.0	0.3	0.0	6.5	1.6	1.9	3.1	1.5	0.9	0.8	0.2	0.4	0.0	1.1	0.2	0.0	0.7	12.8	0.0	2.1	5.4	13.1	12.2	0.1	0.3	0.1	0.4	1.3	0.2	0.6
P4HTM	"EGLN4, FLJ20262, HIFPH4, P4H-TM, PH-4, PH4, PHD4"	ENSG00000178467	"Prolyl 4-hydroxylase, transmembrane"	Q9NXG6	3	48989889-49007153	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"		"Dioxygenase, Oxidoreductase"	"Disease variant, Epilepsy, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Late spermatids: 155.3;Respiratory ciliated cells: 169.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA007199	Supported		Uncertain	Vesicles,Cytosol		NA	NA			"Cluster 26: Non-specific - Mitochondria"	"Cluster 26: Pituitary gland - Hormone signaling"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 49: Ciliated cells - Cilium organization"	"Vesicles, Cytosol"		"HPA007199: AB_1855272"	"unprognostic (1.95e-2)"	"unprognostic (3.12e-2)"	"unprognostic (9.47e-2)"	"prognostic favorable (8.18e-4)"	"unprognostic (7.78e-2)"	"unprognostic (1.05e-1)"	"unprognostic (6.47e-2)"	"unprognostic (2.02e-2)"	"unprognostic (1.89e-2)"	"unprognostic (3.78e-2)"	"unprognostic (2.51e-3)"	"unprognostic (1.54e-2)"	"prognostic favorable (3.28e-5)"	"unprognostic (1.10e-2)"	"unprognostic (3.51e-1)"	"unprognostic (2.60e-2)"	"unprognostic (9.65e-3)"	13.3	37.1	50.6	4.9	53.3	5.9	12.4	44.3	67.9	18.4	89.7	14.7	12.1	17.6	18.7	8.2	39.8	11.2	26.2	53.5	57.3	29.8	11.9	15.7	6.5	52.2	49.6	20.0	38.5	39.4	75.9	11.0	51.5	18.5	7.4	16.4	19.6	16.8	15.2	10.1	13.0	7.4	45.8	10.7	25.1	23.6	53.3	5.5	26.5	11.3	3.8	12.8	13.1	49.6	8.6	27.9	4.8	0.1	15.5	17.6	0.4	16.8	24.6	13.2	14.8	6.3	55.6	8.1	15.8	21.6	10.5	4.8	12.5	6.6	4.1	30.4	19.5	0.0	42.1	0.0	38.6	8.3	0.2	11.0	6.3	13.4	1.1	51.4	15.0	0.1	0.0	37.9	6.5	48.1	1.2	1.0	6.8	52.6	31.2	0.0	0.0	53.5	24.4	15.9	20.9	0.2	17.7	25.0	0.1	1.1	20.1	13.1	9.9	8.0	6.1	19.9	14.5	50.0	28.6	0.1	54.9	0.7	7.1	8.0	9.0	5.9	6.7	3.5	9.6	8.4	12.3	11.7	9.4	15.9	13.0	8.3	0.8	5.9	4.5	1.6	17.0	6.0	50.6	53.3	44.3	67.9	53.5	57.3	52.2	49.6	51.5	45.8	53.3	49.6	15.1	22.4	17.3	36.2	16.1	9.2	34.6	41.1	12.5	72.9	28.7	23.0	12.0	41.5	44.0	46.0	87.6	31.4	13.4	27.4	19.6	38.3	138.4	106.4	23.7	12.6	80.9	12.4	55.7	39.1	9.9	28.1	48.9	31.2	22.9	31.6	15.4	8.5	16.8	117.8	48.6	40.4	65.1	6.3	12.8	155.3	30.4	13.0	12.4	20.6	11.3	58.4	14.4	17.1	32.3	23.6	51.8	25.9	28.9	24.4	56.2	30.4	169.4	72.5	19.7	32.9	24.7	32.5	7.0	12.9	10.4	26.1	25.0	23.9	40.9	31.2
PAH	PH	ENSG00000171759	"Phenylalanine hydroxylase"	P00439	12	102836889-102958410	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Phenylalanine catabolism"	"Allosteric enzyme, Monooxygenase, Oxidoreductase"	"Disease variant, FDA approved drug targets, Phenylketonuria"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	12	"kidney: 496.6;liver: 1408.4"	"Group enriched"	"Detected in some"	6	"Cholangiocytes: 250.2;Hepatocytes: 807.7;Proximal tubular cells: 344.4"	"Cancer enriched"	"Detected in some"	17	"liver cancer: 94.7"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	31	"Hep G2: 238.2"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"HPA028407, HPA031642"	Enhanced		Approved	"Endoplasmic reticulum,Vesicles"		No	NA		40000		"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	"Endoplasmic reticulum, Vesicles"		"HPA028407: AB_10601241, HPA031642: AB_2673974"	"unprognostic (1.16e-1)"	"unprognostic (1.52e-1)"	"unprognostic (4.47e-2)"	"unprognostic (9.13e-3)"	"unprognostic (5.19e-2)"	"unprognostic (5.99e-2)"	"prognostic favorable (4.30e-4)"	"unprognostic (1.27e-1)"	"unprognostic (6.60e-2)"	"unprognostic (4.45e-3)"	"unprognostic (1.94e-3)"	"unprognostic (1.83e-1)"	"unprognostic (1.10e-2)"	"unprognostic (3.51e-1)"	"unprognostic (1.64e-1)"	"unprognostic (3.96e-2)"	"unprognostic (1.68e-2)"	0.2	6.4	2.1	0.0	1.9	0.0	0.2	1.8	3.4	0.1	1.1	0.3	0.1	0.1	0.5	0.0	0.1	79.4	0.0	2.2	2.3	496.6	1408.4	0.0	0.1	2.8	2.3	0.1	9.2	0.8	3.0	0.0	2.3	1.5	0.0	2.4	0.1	0.1	0.0	0.0	0.1	0.0	2.6	0.3	0.4	3.3	2.5	0.7	0.6	0.0	0.0	0.0	0.0	2.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	7.7	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.2	0.3	238.2	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.6	0.0	0.0	0.3	0.2	1.0	0.1	0.2	0.6	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.1	1.9	1.8	3.4	2.2	2.3	2.8	2.3	2.3	2.6	2.5	2.8	0.0	0.0	0.0	1.0	2.7	0.0	0.0	0.0	0.0	1.4	0.2	0.1	0.5	250.2	0.0	5.5	0.0	0.0	0.0	0.0	21.5	2.4	66.8	0.0	0.1	1.1	1.8	21.5	1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	13.9	807.7	0.0	3.3	2.3	0.0	0.0	22.2	0.0	15.7	0.6	1.8	0.0	0.0	0.0	0.6	0.0	4.5	0.0	0.0	0.0	1.2	0.0	0.4	0.0	344.4	0.0	0.2	0.0	0.0	0.0	2.1	0.4	0.0	0.0	0.0	3.3	0.0	0.0	0.1
PAM	"PAL, PHM"	ENSG00000145730	"Peptidylglycine alpha-amidating monooxygenase"	P19021	5	102753981-103031105	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins"		"Lyase, Monooxygenase, Multifunctional enzyme, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 1560.4"	"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 1406.5;Enteroendocrine cells: 321.4;Inhibitory neurons: 487.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"ASC diff: 529.9;fHDF/TERT166: 714.5;hTERT-RPE1: 562.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB026119, HPA042260"	Enhanced		Approved	"Golgi apparatus,Cytosol"	"Secreted in other tissues"	NA	NA		98000000	"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 44: Heart - Cardiac muscle contraction"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 54: Cardiomyocytes - Muscle contraction"	"Golgi apparatus, Cytosol"		"CAB026119: , HPA042260: AB_2677919"	"unprognostic (4.30e-3)"	"unprognostic (1.60e-2)"	"unprognostic (1.12e-1)"	"prognostic favorable (1.63e-4)"	"unprognostic (4.23e-2)"	"unprognostic (6.30e-2)"	"prognostic unfavorable (6.20e-4)"	"unprognostic (7.58e-2)"	"unprognostic (6.62e-2)"	"unprognostic (2.71e-1)"	"unprognostic (9.91e-2)"	"unprognostic (3.18e-1)"	"unprognostic (1.86e-2)"	"unprognostic (1.08e-1)"	"unprognostic (9.79e-2)"	"unprognostic (5.51e-2)"	"unprognostic (8.80e-3)"	119.3	202.5	71.6	34.6	81.4	10.1	99.0	50.7	82.5	595.0	96.2	125.1	52.6	140.9	678.2	69.4	87.6	97.3	1560.4	75.2	179.9	116.0	20.1	88.3	27.7	86.5	99.8	136.4	104.4	257.8	137.0	60.0	170.9	91.6	80.4	37.6	205.4	236.5	155.3	66.9	52.1	157.9	55.7	52.5	131.6	22.4	106.0	17.9	95.1	159.4	30.5	103.3	116.1	50.0	111.3	16.3	195.9	87.2	529.9	314.8	78.0	307.6	457.0	89.1	268.9	53.5	143.2	0.1	65.0	714.5	125.7	36.8	11.0	135.3	244.0	13.5	44.7	22.9	60.0	17.7	80.3	7.4	23.9	173.4	57.3	65.6	49.2	562.6	186.8	8.9	0.9	15.0	255.6	22.9	0.1	3.2	35.3	19.7	59.3	8.5	108.9	62.4	346.1	13.0	92.3	63.9	131.2	8.3	83.3	114.0	34.0	7.3	144.9	280.8	72.4	133.3	93.4	33.1	8.6	0.4	322.3	30.8	247.6	4.2	8.0	0.2	20.7	1.5	14.9	0.8	12.3	15.6	3.1	0.4	4.1	6.8	16.6	26.3	3.4	1.6	19.9	10.8	71.6	81.4	50.7	82.5	75.2	179.9	86.5	99.8	170.9	55.7	106.0	50.0	45.7	54.5	39.3	47.0	3.9	28.2	12.0	26.1	12.0	19.1	27.5	12.1	1406.5	0.0	30.4	60.7	2.1	1.6	12.6	13.7	7.9	12.6	8.8	47.6	48.6	63.5	321.4	3.4	229.2	21.5	40.6	220.4	26.0	83.0	9.5	68.3	74.6	3.5	5.9	8.4	487.7	13.8	18.3	10.3	48.3	8.1	60.3	9.3	37.4	192.0	9.5	11.6	22.6	154.8	9.3	30.6	6.3	58.6	12.1	26.4	4.8	43.8	19.2	3.8	19.7	36.4	44.9	2.6	5.6	8.0	23.7	6.7	16.6	19.3	6.3	18.2
PAOX	PAO	ENSG00000148832	"Polyamine oxidase"	Q6QHF9	10	133379261-133391694	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"testis: 27.4"	"Group enriched"	"Detected in many"	6	"Early spermatids: 143.4;Late spermatids: 456.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in some"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"A-431: 5.7;K-562: 3.9;U-266/70: 13.7"									HPA047782			Uncertain	Nucleoplasm,Centrosome		NA	NA			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 71: Testis - DNA repair"	"Cluster 29: U-266 - Adaptive immune response"	"Cluster 31: Spermatids - Spermatogenesis"	Centrosome	Nucleoplasm	"HPA047782: "	"unprognostic (3.67e-3)"	"prognostic favorable (6.07e-5)"	"unprognostic (2.49e-2)"	"unprognostic (1.28e-3)"	"unprognostic (1.96e-2)"	"prognostic favorable (1.38e-5)"	"unprognostic (7.39e-2)"	"unprognostic (1.99e-3)"	"unprognostic (2.20e-1)"	"unprognostic (4.48e-2)"	"unprognostic (1.11e-2)"	"unprognostic (2.99e-1)"	"prognostic favorable (9.49e-4)"	"unprognostic (3.56e-2)"	"unprognostic (2.86e-1)"	"unprognostic (7.61e-2)"	"unprognostic (8.29e-3)"	1.9	2.3	0.6	0.5	1.1	0.0	1.9	0.9	1.5	2.8	1.1	2.6	1.8	2.5	0.0	6.2	2.7	0.1	1.5	0.6	0.5	3.4	7.7	1.5	0.5	0.8	0.6	2.4	2.5	0.3	1.6	0.1	0.8	2.7	0.0	0.0	3.1	1.1	3.1	2.8	4.4	0.3	0.9	4.8	2.5	27.4	0.5	0.1	1.6	0.0	0.4	2.8	3.3	1.6	5.7	0.0	0.3	1.2	0.0	0.5	0.4	1.5	1.1	1.7	0.1	0.5	0.1	0.0	0.4	0.7	0.4	1.8	0.0	0.7	0.3	2.7	0.0	0.4	0.0	0.0	1.3	0.0	0.3	0.0	0.1	0.4	0.1	0.0	0.0	0.0	3.9	0.4	0.0	0.1	0.0	0.2	0.6	0.0	1.9	3.3	0.0	0.0	0.1	0.0	0.1	1.3	1.1	0.0	0.0	0.0	1.4	0.0	1.8	0.0	0.6	1.1	0.0	13.7	2.8	1.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.6	0.0	0.0	0.3	0.8	0.0	0.0	0.0	0.1	0.1	0.1	0.0	0.1	0.6	1.1	0.9	1.5	0.6	0.5	0.8	0.6	0.8	0.9	0.5	1.6	3.8	0.0	4.6	4.2	17.5	3.7	8.5	3.4	8.6	4.0	4.2	5.0	1.7	8.6	1.9	1.8	0.0	1.1	5.8	4.3	5.9	5.4	143.4	4.0	3.0	3.3	0.0	1.3	3.3	3.3	2.3	3.6	5.6	3.9	5.7	2.5	3.3	13.5	4.6	5.0	1.7	4.0	4.1	14.5	2.3	456.3	9.6	9.0	0.0	3.7	12.3	9.2	2.1	3.0	9.7	3.4	3.4	7.9	22.0	8.7	29.9	18.0	3.3	3.0	19.7	2.4	3.6	46.9	6.0	12.8	3.7	0.3	5.4	3.7	4.1	10.5
PCYOX1	"KIAA0908, PCL1"	ENSG00000116005	"Prenylcysteine oxidase 1"	Q9UHG3	2	70257386-70281185	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Alveolar cells type 1: 599.4;Hepatocytes: 187.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"ASC diff: 313.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA035193	Approved				"Intracellular and membrane"	NA	NA		510000000	"Cluster 44: Non-specific - Transcription"	"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 11: Alveolar cells - Smell perception"			"HPA035193: AB_10602017"	"unprognostic (1.09e-1)"	"unprognostic (1.72e-2)"	"unprognostic (7.91e-2)"	"unprognostic (1.15e-2)"	"unprognostic (1.44e-1)"	"unprognostic (2.05e-1)"	"unprognostic (6.87e-2)"	"unprognostic (6.28e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.80e-1)"	"unprognostic (1.61e-1)"	"unprognostic (4.38e-2)"	"prognostic favorable (1.89e-4)"	"unprognostic (3.26e-2)"	"unprognostic (1.55e-1)"	"unprognostic (1.13e-1)"	"unprognostic (1.54e-2)"	78.5	33.5	15.4	12.7	15.7	3.7	34.4	12.1	18.4	56.5	29.3	26.9	24.9	39.9	33.6	38.8	35.6	31.7	37.7	14.7	27.8	92.6	103.5	56.2	14.6	16.5	22.0	39.6	20.6	66.0	17.9	29.0	24.9	44.3	23.6	30.7	70.1	46.6	92.1	33.0	24.5	40.8	14.6	15.6	22.1	14.2	28.4	11.1	60.0	50.4	14.2	25.7	25.2	13.2	38.8	54.9	43.2	48.6	313.2	160.0	37.9	64.8	59.4	35.4	26.5	86.5	33.6	4.0	27.3	89.2	58.2	62.2	31.7	50.2	40.5	22.1	26.9	14.9	41.0	75.7	31.4	14.1	12.7	154.9	54.1	47.4	13.3	93.9	42.6	14.2	27.0	27.8	50.7	23.6	10.7	22.8	26.1	55.9	23.1	19.6	90.2	34.5	50.1	42.8	11.3	24.1	97.8	47.7	45.5	61.0	39.1	18.2	53.4	59.2	32.7	52.9	34.2	22.9	55.1	5.1	71.3	19.3	22.1	16.3	6.5	6.8	8.3	5.4	10.4	3.7	8.0	6.7	5.9	2.8	10.8	9.2	4.1	6.1	6.0	7.4	7.8	6.5	15.4	15.7	12.1	18.4	14.7	27.8	16.5	22.0	24.9	14.6	28.4	13.2	37.3	599.4	77.5	16.0	12.2	21.3	23.1	43.9	29.6	48.7	46.0	31.8	81.1	40.0	49.9	53.3	43.8	43.4	12.1	30.7	7.9	26.7	1.7	18.4	65.9	33.4	8.5	12.0	24.7	10.2	36.0	81.9	22.4	36.2	10.1	20.9	39.7	187.8	22.1	57.2	36.8	21.0	36.7	17.4	9.2	3.9	89.2	14.3	24.9	23.4	8.6	90.3	11.3	21.6	18.0	13.9	21.0	120.7	26.2	27.0	47.7	69.0	25.0	36.9	72.3	65.5	63.7	14.7	32.2	40.8	28.3	22.0	14.5	56.2	26.5	18.4
PDHA1	PDHA	ENSG00000131828	"Pyruvate dehydrogenase E1 subunit alpha 1"	P08559	X	19343893-19361718	"Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle"	Oxidoreductase	"Disease variant, Leigh syndrome, Primary mitochondrial disease"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 508.8;tongue: 770.2"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 479.9;Distal tubular cells: 354.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA047487, HPA047864, HPA063053"	Approved		Supported	Mitochondria	"Intracellular and membrane"	NA	NA		100000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 18: U-2197 - ECM organization"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria		"HPA047487: AB_2680066, HPA047864: AB_2680190, HPA063053: AB_2684931"	"unprognostic (5.71e-3)"	"unprognostic (2.46e-3)"	"unprognostic (5.71e-2)"	"unprognostic (3.36e-3)"	"unprognostic (3.12e-2)"	"unprognostic (2.27e-2)"	"unprognostic (1.37e-2)"	"unprognostic (4.28e-1)"	"unprognostic (1.01e-1)"	"unprognostic (7.01e-3)"	"unprognostic (6.90e-2)"	"unprognostic (8.68e-2)"	"prognostic favorable (1.13e-7)"	"unprognostic (3.72e-2)"	"unprognostic (3.03e-1)"	"unprognostic (1.92e-2)"	"unprognostic (9.06e-2)"	93.0	69.0	62.1	37.9	66.9	88.1	63.1	66.2	91.5	55.9	84.4	112.6	87.0	53.1	78.9	76.8	49.1	29.3	508.8	68.2	67.0	174.1	118.3	47.2	36.6	64.5	62.7	50.6	83.4	161.0	48.7	43.1	65.0	48.4	104.4	90.1	109.7	63.4	459.0	60.9	82.1	51.8	59.6	49.3	121.8	24.0	67.4	52.3	64.5	770.2	59.1	61.7	56.1	71.1	124.9	151.4	107.9	114.2	102.3	77.7	131.6	83.8	74.6	170.2	130.7	216.6	78.2	212.2	60.6	102.0	226.7	159.0	334.2	145.8	178.1	70.1	186.1	104.8	264.0	194.2	107.8	170.3	82.8	100.9	132.8	157.3	154.4	85.6	105.3	129.8	94.2	87.2	120.7	164.5	142.7	173.5	110.0	227.4	261.7	145.2	180.9	260.3	298.0	125.1	59.7	62.6	134.1	167.8	158.1	229.8	177.1	118.1	65.4	87.6	78.6	240.9	108.6	73.3	82.0	140.5	82.4	117.2	77.4	99.9	87.4	65.3	72.3	119.9	88.9	103.4	69.4	79.5	115.7	82.1	67.7	72.0	15.5	98.1	109.1	76.9	84.4	89.6	62.1	66.9	66.2	91.5	68.2	67.0	64.5	62.7	65.0	59.6	67.4	71.1	34.1	44.8	44.4	18.6	30.7	29.8	59.7	135.4	25.0	59.0	37.0	29.3	479.9	87.2	74.8	152.6	33.3	105.0	32.5	73.0	354.1	88.8	2.5	41.2	33.7	36.8	41.9	55.8	21.2	59.8	120.7	49.2	49.5	36.9	42.6	39.7	18.2	76.3	73.2	25.2	24.6	64.4	71.2	26.8	30.5	4.1	35.4	32.5	56.9	9.4	40.8	49.0	26.8	13.0	11.5	47.4	52.5	40.6	43.3	47.1	88.6	213.7	33.1	69.1	32.9	37.5	51.7	51.1	25.3	45.2	33.4	133.4	31.6	25.4	130.3	55.8
PDHA2	PDHAL	ENSG00000163114	"Pyruvate dehydrogenase E1 subunit alpha 2"	P29803	4	95840093-95841464	"Citric acid cycle related proteins, Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	602	"testis: 60.2"	"Group enriched"	"Detected in some"	71	"Early spermatids: 426.6;Late spermatids: 288.3;Spermatocytes: 229.6"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"							"HPA047487, HPA047864, HPA063053"	Approved		Supported	Mitochondria		NA	NA				"Cluster 36: Testis - Spermatogenesis"		"Cluster 66: Spermatocytes - Spermatogenesis"	Mitochondria		"HPA047487: AB_2680066, HPA047864: AB_2680190, HPA063053: AB_2684931"																		0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	60.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	426.6	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	288.3	4.4	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	229.6	3.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0
PDHB	PDHE1B	ENSG00000168291	"Pyruvate dehydrogenase E1 subunit beta"	P11177	3	58427630-58433857	"Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"tongue: 299.4"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 300.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB033794, HPA036744, HPA036745"	Enhanced		Supported	Nucleoplasm,Mitochondria		No	No		61000	"Cluster 27: Non-specific - Gene expression"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria	Nucleoplasm	"CAB033794: AB_2162946, HPA036744: AB_10670921, HPA036745: AB_2675285"	"unprognostic (2.06e-2)"	"unprognostic (1.79e-1)"	"unprognostic (6.04e-3)"	"unprognostic (1.22e-1)"	"unprognostic (7.22e-2)"	"unprognostic (1.42e-1)"	"unprognostic (3.20e-2)"	"unprognostic (6.13e-2)"	"unprognostic (9.62e-2)"	"unprognostic (5.94e-2)"	"unprognostic (3.98e-1)"	"unprognostic (2.35e-1)"	"prognostic favorable (2.79e-8)"	"unprognostic (2.67e-1)"	"unprognostic (8.37e-2)"	"unprognostic (1.06e-2)"	"unprognostic (9.85e-2)"	59.9	76.5	48.7	42.2	50.2	25.7	42.9	53.9	62.7	43.3	63.6	56.8	42.5	38.5	44.6	57.4	37.7	35.9	175.0	49.7	52.3	100.8	110.7	36.4	53.1	51.7	49.4	26.5	36.4	88.8	44.1	57.0	51.5	48.5	60.4	30.7	45.9	52.1	272.6	36.8	37.6	63.8	51.6	42.8	53.9	42.3	53.1	53.1	40.8	299.4	56.0	49.7	35.9	54.3	66.5	90.9	92.3	69.8	91.7	111.1	110.4	81.6	101.3	117.9	120.6	165.1	62.6	140.3	44.9	103.8	109.0	37.6	113.2	74.9	90.0	81.7	83.0	125.4	163.7	126.0	92.5	103.0	67.9	97.9	67.7	95.5	55.8	137.5	103.1	114.2	65.9	61.5	129.5	63.1	98.2	107.8	127.2	69.2	101.3	46.3	71.8	136.1	188.1	89.1	63.7	70.2	75.6	107.2	85.4	131.3	159.0	108.7	76.3	62.9	83.7	66.8	94.2	85.2	129.9	99.2	96.2	120.8	60.7	57.8	98.9	98.7	83.2	115.1	87.9	102.2	81.7	80.5	141.1	103.4	90.9	82.4	19.6	129.4	109.7	94.7	113.2	124.1	48.7	50.2	53.9	62.7	49.7	52.3	51.7	49.4	51.5	51.6	53.1	54.3	57.8	60.9	34.5	5.9	45.3	27.9	40.7	142.0	26.7	31.8	29.4	31.6	300.6	48.6	96.0	35.0	25.0	174.1	35.3	41.0	230.9	95.9	76.3	37.0	37.3	58.0	58.0	22.5	10.9	72.2	101.6	54.1	29.6	34.2	39.3	48.5	46.1	76.1	84.6	57.2	13.3	50.4	162.8	37.9	26.6	16.9	60.3	37.2	56.9	9.4	76.5	61.7	70.0	9.0	13.6	55.9	43.0	51.1	38.8	19.1	45.8	146.8	70.7	45.9	65.7	30.8	72.3	98.2	88.3	42.8	29.8	157.2	44.7	224.4	53.0	37.7
PECR	"HSA250303, SDR29C1, TERP"	ENSG00000115425	"Peroxisomal trans-2-enoyl-CoA reductase"	Q9BY49	2	215996329-216082955	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"liver: 160.2"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 91.0;Proximal enterocytes: 49.5;Proximal tubular cells: 79.1"	"Cancer enhanced"	"Detected in all"		"liver cancer: 30.4"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"Hep G2: 38.3;RPTEC TERT1: 35.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA021593, HPA022539"	Enhanced		Supported	Peroxisomes		NA	NA			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 85: Liver - Metabolism"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Peroxisomes		"HPA021593: AB_1855177, HPA022539: AB_1855178"	"unprognostic (7.97e-2)"	"unprognostic (1.08e-1)"	"unprognostic (5.72e-2)"	"unprognostic (1.32e-3)"	"unprognostic (2.90e-1)"	"unprognostic (6.40e-2)"	"unprognostic (1.16e-3)"	"unprognostic (3.56e-2)"	"unprognostic (4.03e-2)"	"unprognostic (1.11e-1)"	"unprognostic (5.01e-3)"	"unprognostic (5.61e-2)"	"prognostic favorable (1.36e-5)"	"unprognostic (6.63e-2)"	"unprognostic (1.84e-2)"	"unprognostic (7.75e-2)"	"unprognostic (6.64e-2)"	25.4	5.4	2.7	2.9	3.1	7.1	10.2	3.8	2.9	4.5	6.0	8.7	26.0	3.3	4.1	3.1	8.1	9.7	2.4	2.7	2.8	33.9	160.2	6.4	3.9	3.2	3.1	4.1	4.8	7.2	3.2	1.0	3.3	5.0	7.5	2.2	5.6	3.4	6.8	4.2	20.1	3.2	2.6	3.0	3.9	0.5	3.0	3.4	16.1	5.2	3.8	2.3	2.3	3.7	6.0	6.6	2.6	0.1	15.7	5.7	3.1	1.4	3.3	3.7	6.3	7.6	17.1	0.1	11.9	3.5	9.2	1.4	7.5	8.7	6.5	9.5	7.7	7.8	3.6	38.3	15.7	2.0	5.1	5.0	6.1	3.9	5.5	5.6	3.8	4.6	3.3	8.6	8.2	4.4	2.4	2.2	4.8	0.1	4.9	5.3	5.0	0.9	35.9	1.0	3.6	5.2	3.6	7.4	15.6	6.2	8.6	6.5	0.0	2.4	2.5	6.0	4.3	9.8	8.9	3.1	5.3	2.8	5.6	1.2	4.2	1.5	6.5	1.6	7.7	4.3	8.8	7.5	1.5	5.7	9.2	6.1	4.5	9.9	2.3	0.2	16.6	4.1	2.7	3.1	3.8	2.9	2.7	2.8	3.2	3.1	3.3	2.6	3.0	3.7	4.3	6.4	13.6	6.5	7.0	3.7	4.7	4.0	3.4	10.8	2.4	2.9	3.7	35.8	3.4	29.5	14.6	3.9	5.9	11.5	13.7	13.2	0.1	10.1	2.7	3.9	7.2	9.4	15.4	3.8	7.3	5.0	7.7	6.3	1.3	2.0	6.8	91.0	9.6	3.3	18.4	8.0	6.1	4.7	3.7	0.3	5.6	5.5	10.6	8.4	27.4	10.1	9.2	8.5	10.6	5.0	17.7	8.2	5.9	2.0	49.5	79.1	13.1	6.4	0.0	6.6	4.4	0.1	1.6	4.9	2.8	1.6	11.4	1.9	14.6	2.7
PEDS1	"CarF, Kua, TMEM189"	ENSG00000240849	"Plasmanylethanolamine desaturase 1"	A5PLL7	20	50118254-50153734	"Enzymes, Predicted membrane proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"Cytotrophoblasts: 86.8;Extravillous trophoblasts: 167.6;Hofbauer cells: 38.6;Syncytiotrophoblasts: 50.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA059549	Approved		Supported	"Endoplasmic reticulum"		NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 38: Extravillous trophoblasts - Unknown function"	"Endoplasmic reticulum"		"HPA059549: AB_2684059"	"unprognostic (3.11e-2)"	"unprognostic (7.04e-3)"	"unprognostic (1.56e-2)"	"prognostic unfavorable (7.51e-4)"	"unprognostic (1.71e-1)"	"unprognostic (1.04e-1)"	"unprognostic (2.03e-3)"	"unprognostic (7.00e-2)"	"unprognostic (2.19e-2)"	"unprognostic (1.35e-1)"	"unprognostic (8.63e-2)"	"unprognostic (5.79e-2)"	"prognostic unfavorable (5.79e-11)"	"unprognostic (1.85e-1)"	"unprognostic (1.20e-1)"	"unprognostic (9.46e-2)"	"unprognostic (4.42e-2)"	13.2	14.0	19.6	7.3	24.0	5.7	10.4	25.3	24.3	12.7	15.8	18.4	8.7	13.8	10.7	26.0	9.1	7.2	20.8	19.6	20.8	9.3	17.8	13.7	6.0	25.8	24.4	5.5	9.3	12.8	5.8	17.6	24.1	11.6	7.1	2.2	12.4	13.5	16.9	22.9	9.8	21.8	21.0	10.0	15.1	6.3	23.3	7.8	7.7	16.3	7.4	15.4	15.1	29.1	19.6	17.7	20.7	16.3	30.7	23.0	34.6	13.6	12.6	27.8	15.6	48.6	30.5	7.2	21.2	12.8	39.7	52.8	10.4	27.4	10.0	3.8	8.0	9.3	24.5	41.6	17.3	15.1	24.2	19.7	62.7	15.6	16.4	13.4	33.6	12.2	9.8	10.2	9.5	17.3	12.0	38.1	10.1	50.1	18.3	9.7	15.9	7.8	53.7	28.4	10.8	7.1	15.4	52.2	32.4	20.3	8.3	21.2	26.8	23.1	12.1	15.1	13.5	7.5	13.6	2.9	19.9	11.1	19.1	4.9	5.3	6.2	3.1	10.2	2.6	1.8	3.5	2.6	5.6	1.5	2.9	3.4	2.0	4.0	14.0	3.6	5.6	3.8	19.6	24.0	25.3	24.3	19.6	20.8	25.8	24.4	24.1	21.0	23.3	29.1	8.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	16.8	0.0	0.0	0.0	0.0	86.8	6.3	0.0	0.0	0.0	0.0	0.0	0.0	4.9	0.0	0.0	0.0	0.0	167.6	6.3	0.0	0.0	0.0	0.0	0.0	0.0	38.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.9	0.0	0.0	0.0	0.0	50.1	1.2	0.0	0.0	0.0
PGD		ENSG00000142657	"Phosphogluconate dehydrogenase"	P52209	1	10398592-10420511	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Gluconate utilization, Pentose shunt"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 400.2;esophagus: 572.4"	"Cell type enhanced"	"Detected in all"		"monocytes: 214.9;Squamous epithelial cells: 496.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"basophil: 1060.2;classical monocyte: 321.0;eosinophil: 1074.7;neutrophil: 332.6"	"Group enriched"	"Detected in all"	5	"granulocytes: 1074.7;monocytes: 321.0"	"Cell line enhanced"	"Detected in all"		"A549: 1445.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA031314, HPA031315"	Enhanced	Supported	Approved	"Intermediate filaments,Cytosol"		No	No		41000000	"Cluster 2: Granulocytes - Unknown function"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 61: Squamous epithelial cells - Keratinization"	"Intermediate filaments, Cytosol"		"HPA031314: AB_10610278, HPA031315: AB_2673825"	"unprognostic (4.65e-2)"	"unprognostic (2.58e-1)"	"unprognostic (8.65e-2)"	"unprognostic (9.80e-2)"	"unprognostic (1.31e-2)"	"unprognostic (2.28e-1)"	"prognostic unfavorable (3.98e-4)"	"unprognostic (1.90e-2)"	"unprognostic (2.83e-1)"	"unprognostic (1.40e-2)"	"unprognostic (4.92e-1)"	"unprognostic (1.36e-1)"	"unprognostic (1.37e-3)"	"unprognostic (1.43e-1)"	"unprognostic (1.49e-1)"	"unprognostic (2.43e-3)"	"unprognostic (1.14e-1)"	115.8	51.0	49.5	59.8	49.2	400.2	89.0	52.9	49.3	75.9	52.5	52.9	91.6	23.1	41.9	572.4	30.0	94.2	34.3	47.4	54.3	53.2	81.3	88.5	38.1	57.0	54.6	35.7	32.0	52.7	43.8	47.4	55.4	30.4	46.3	49.1	133.7	22.9	34.7	50.0	70.7	35.0	49.7	110.4	61.4	68.3	59.2	53.6	71.8	28.2	73.8	61.8	126.9	52.0	191.5	1445.2	319.3	340.6	445.4	274.0	71.8	124.8	185.9	144.4	195.3	219.2	190.4	163.5	151.0	109.2	202.4	148.0	225.6	192.1	96.4	127.5	199.9	227.8	264.3	452.1	136.3	390.9	249.7	196.5	92.2	229.4	55.5	186.9	344.0	223.0	305.3	145.7	183.5	202.5	321.4	179.4	194.7	221.0	109.1	252.7	298.1	312.2	199.6	105.5	178.0	154.1	99.1	153.5	137.5	196.7	173.3	308.5	369.3	81.1	149.6	98.3	134.5	111.6	256.0	323.5	175.1	393.9	73.6	1060.2	321.0	1074.7	23.2	137.7	26.5	33.1	21.4	20.8	144.6	23.3	21.1	22.3	332.6	19.7	105.6	98.7	23.1	225.0	49.5	49.2	52.9	49.3	47.4	54.3	57.0	54.6	55.4	49.7	59.2	52.0	7.4	19.2	35.0	11.8	24.9	13.0	30.8	78.0	70.6	7.8	30.4	18.5	11.0	50.1	73.2	20.2	18.8	134.6	29.8	24.3	52.8	52.1	10.9	17.8	18.6	22.6	23.4	55.7	8.6	40.3	40.7	37.5	41.8	24.5	25.9	53.9	16.1	66.2	134.6	1.7	12.6	30.2	59.0	163.8	30.9	13.4	17.1	150.9	17.8	4.7	214.9	16.5	10.3	13.6	9.0	38.7	26.7	10.5	41.9	43.5	66.6	55.1	46.2	20.2	19.7	23.4	21.5	41.5	38.4	496.0	16.6	81.3	19.4	27.3	51.7	76.1
PHF8	"JHDM1F, KDM7B, KIAA1111, ZNF422"	ENSG00000172943	"PHD finger protein 8"	Q9UPP1	X	53936676-54048958	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, Transcription, Transcription regulation"	"Activator, Chromatin regulator, Dioxygenase, Oxidoreductase"	"Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"epididymis: 70.6"	"Cell type enhanced"	"Detected in many"		"Spermatocytes: 57.9;Spermatogonia: 58.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA038779, HPA062015"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 68: Epididymis - Unknown function"	"Cluster 5: NTERA-2 - Transcription"	"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis"	Nucleoplasm		"HPA038779: AB_10675950, HPA062015: AB_2684658"	"unprognostic (6.35e-2)"	"unprognostic (2.16e-2)"	"unprognostic (1.70e-2)"	"unprognostic (1.04e-1)"	"unprognostic (8.76e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.40e-1)"	"unprognostic (2.66e-3)"	"unprognostic (1.97e-3)"	"unprognostic (1.22e-1)"	"unprognostic (5.64e-2)"	"unprognostic (1.02e-1)"	"unprognostic (5.17e-2)"	"unprognostic (1.22e-1)"	"unprognostic (9.94e-2)"	"unprognostic (1.85e-2)"	"prognostic favorable (3.74e-5)"	11.6	8.1	8.3	13.3	11.1	16.2	13.8	9.5	10.3	13.9	20.0	11.6	10.3	14.1	70.6	13.4	14.1	9.2	9.8	7.8	11.2	9.7	28.7	13.5	16.3	10.1	9.4	19.3	17.8	10.8	13.9	13.2	11.2	16.0	9.6	14.6	12.8	18.3	11.0	13.1	14.2	9.4	8.1	13.9	12.7	40.1	10.2	18.6	13.2	7.8	15.8	14.1	13.5	13.3	16.1	14.0	20.4	19.9	12.2	9.6	33.3	12.0	10.4	12.9	11.4	15.7	12.8	23.4	6.9	10.8	13.9	16.5	51.1	10.3	13.7	36.4	23.8	14.2	18.1	15.8	9.6	22.4	25.6	10.9	14.0	15.0	20.2	9.7	12.0	24.3	18.7	33.2	7.6	16.1	30.6	16.9	37.2	11.0	19.6	29.7	22.5	22.9	8.9	19.2	29.2	14.5	31.6	20.5	10.5	31.2	20.5	15.5	14.3	10.3	14.5	19.2	10.0	25.1	25.4	28.3	12.2	27.9	11.3	6.1	2.7	4.4	3.2	4.8	5.1	2.3	3.3	3.9	2.9	3.1	2.5	2.8	4.4	3.5	3.2	2.3	5.3	3.4	8.3	11.1	9.5	10.3	7.8	11.2	10.1	9.4	11.2	8.1	10.2	13.3	9.5	9.6	10.3	17.3	11.2	8.9	9.4	4.5	15.4	13.7	13.9	8.1	7.8	5.7	5.4	9.2	12.5	13.9	14.1	8.3	0.0	5.1	54.9	34.5	11.3	11.3	5.4	5.2	19.7	4.6	4.7	6.9	10.7	40.2	14.0	15.0	7.9	39.4	6.8	8.4	22.0	8.8	10.2	11.8	6.4	31.4	9.3	11.6	3.6	20.6	9.2	6.1	9.2	27.2	30.0	4.4	9.4	6.4	14.4	10.9	9.2	3.7	16.5	15.3	6.6	11.6	9.2	57.9	58.7	15.2	9.8	12.2	13.5	6.3	8.3	14.7
PHGDH	"PDG, PGDH, SERA"	ENSG00000092621	"Phosphoglycerate dehydrogenase"	O43175	1	119648411-119744218	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Amino-acid biosynthesis, Serine biosynthesis"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 135.0;Exocrine glandular cells: 136.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"naive CD8 T-cell: 25.2"	"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"SK-MEL-30: 975.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB003681, HPA021241, HPA024031, CAB068216"	Enhanced		Enhanced	"Nucleoplasm,Plasma membrane,Cytosol"		No	No		1100000	"Cluster 32: T-cells - Unknown function"	"Cluster 22: Non-specific - Unknown function"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 33: Fibroblasts - ECM organization"	"Plasma membrane, Cytosol"	Nucleoplasm	"CAB003681: AB_425928, CAB068216: AB_2665666, HPA021241: AB_1855299, HPA024031: AB_1855300"	"unprognostic (2.30e-1)"	"unprognostic (2.16e-1)"	"unprognostic (1.80e-2)"	"prognostic unfavorable (1.48e-4)"	"prognostic favorable (1.62e-4)"	"unprognostic (9.80e-2)"	"unprognostic (1.56e-2)"	"unprognostic (1.40e-1)"	"unprognostic (5.24e-2)"	"unprognostic (4.45e-3)"	"unprognostic (8.80e-3)"	"unprognostic (5.00e-2)"	"unprognostic (2.37e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.74e-1)"	"unprognostic (1.95e-1)"	"unprognostic (1.78e-3)"	51.4	3.0	113.6	9.4	125.3	11.4	30.1	130.7	125.9	46.1	89.1	27.2	7.6	25.4	79.6	56.6	49.3	7.6	22.4	108.8	128.8	40.9	126.0	18.0	14.9	121.8	113.9	46.1	171.1	103.9	23.7	13.2	122.4	52.6	7.0	7.5	156.2	33.5	2.6	92.5	13.3	15.0	117.0	6.5	41.7	40.3	115.8	34.0	29.5	4.3	13.3	35.8	62.9	153.6	156.8	35.2	148.0	444.6	64.9	82.8	286.1	101.0	209.3	132.9	257.6	195.7	28.6	0.1	58.1	270.5	16.6	205.6	216.8	224.6	83.9	1.1	162.1	29.1	151.3	153.3	135.7	214.3	1.7	147.6	338.6	146.8	142.2	83.0	100.1	519.7	71.4	443.9	66.8	380.9	222.8	90.1	440.0	93.3	274.6	228.0	181.1	24.8	9.6	120.4	160.8	146.0	65.9	63.9	975.9	103.9	164.8	505.7	0.9	38.3	172.1	207.3	134.8	294.0	79.9	246.1	456.9	328.2	302.7	5.3	1.1	0.2	4.7	0.3	0.2	11.1	2.4	8.2	5.3	4.0	13.0	25.2	2.2	1.8	0.3	2.6	4.5	6.3	113.6	125.3	130.7	125.9	108.8	128.8	121.8	113.9	122.4	117.0	115.8	153.6	5.3	3.2	12.6	31.6	10.0	51.9	118.1	24.2	42.7	0.7	29.7	38.0	2.1	128.7	12.5	20.2	2.1	49.9	2.2	1.6	135.0	60.2	51.2	15.6	3.8	6.9	1.8	5.5	0.3	136.1	54.0	58.7	8.6	12.2	5.7	30.9	3.6	96.1	9.2	0.0	0.6	3.6	18.3	2.2	4.3	116.9	67.7	6.5	56.9	2.8	11.0	82.4	0.0	14.1	32.3	35.6	2.0	127.9	27.4	62.1	0.2	118.4	24.7	3.4	13.1	11.2	48.8	20.0	19.4	57.5	77.1	25.3	5.9	71.4	3.2	56.8
PHYH	"PAHX, PHYH1, RD"	ENSG00000107537	"Phytanoyl-CoA 2-hydroxylase"	O14832	10	13277796-13302412	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"	"Cataract, Deafness, Disease variant, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 667.8;skeletal muscle: 483.6;tongue: 412.7"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 258.6;Proximal tubular cells: 414.6"	"Cancer enhanced"	"Detected in all"		"liver cancer: 78.1"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"ASC diff: 110.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA007598, HPA011796"	Enhanced					NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA007598: AB_1855334, HPA011796: AB_1855335"	"unprognostic (5.78e-2)"	"unprognostic (3.83e-1)"	"unprognostic (6.98e-2)"	"unprognostic (3.62e-2)"	"unprognostic (5.52e-2)"	"unprognostic (1.61e-3)"	"unprognostic (1.16e-1)"	"unprognostic (1.95e-2)"	"unprognostic (7.09e-2)"	"unprognostic (6.15e-2)"	"unprognostic (1.59e-1)"	"unprognostic (3.24e-1)"	"prognostic favorable (7.28e-12)"	"unprognostic (2.07e-1)"	"unprognostic (1.06e-1)"	"unprognostic (1.07e-2)"	"unprognostic (2.19e-1)"	57.9	66.5	22.9	9.5	23.7	8.2	32.2	23.5	28.3	28.8	31.7	46.5	58.7	22.1	16.7	22.9	16.7	28.2	126.5	21.7	24.1	191.4	667.8	17.3	7.5	21.6	24.4	36.8	48.2	56.7	20.9	19.3	22.8	22.5	37.2	28.2	33.7	25.4	483.6	17.5	55.8	23.2	22.7	12.8	44.2	15.1	26.0	5.6	56.0	412.7	5.4	27.0	14.8	23.6	17.2	35.2	15.6	22.5	110.7	69.9	12.4	17.2	23.9	19.4	19.1	9.1	30.3	0.9	12.9	29.0	47.0	7.8	20.5	20.2	11.8	41.4	10.7	14.9	9.3	36.6	54.8	2.5	26.8	50.3	28.9	21.0	8.4	22.7	18.7	16.8	8.4	32.2	45.5	16.3	9.2	12.1	14.4	49.4	12.6	15.7	24.1	5.8	40.6	21.9	5.3	16.8	64.8	1.4	32.9	12.5	64.8	44.2	6.4	29.5	10.6	36.4	11.8	36.6	26.3	3.3	38.3	18.9	11.6	16.3	18.7	8.2	8.0	14.2	17.6	11.0	9.9	10.4	15.8	5.6	12.5	12.7	0.8	4.4	11.2	14.4	10.5	12.3	22.9	23.7	23.5	28.3	21.7	24.1	21.6	24.4	22.8	22.7	26.0	23.6	53.6	12.8	19.2	8.5	14.5	11.9	27.6	19.1	6.2	47.0	22.6	24.5	258.6	77.2	19.7	35.0	22.9	137.8	20.5	72.9	144.8	40.6	33.1	18.5	29.0	29.7	31.8	15.2	7.1	19.6	34.3	41.3	41.8	26.8	30.4	28.3	25.0	145.5	55.4	21.9	5.6	57.4	46.8	21.0	22.0	45.4	25.4	25.3	17.8	4.7	10.3	69.3	7.2	2.5	2.4	16.7	46.0	37.6	15.1	11.9	141.9	414.6	19.6	41.8	19.7	30.2	37.5	12.5	1.6	7.3	13.4	83.9	25.2	103.3	46.9	18.1
PIPOX	LPIPOX	ENSG00000179761	"Pipecolic acid and sarcosine oxidase"	Q9P0Z9	17	28950513-29057216	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	13	"kidney: 146.0;liver: 506.6"	"Group enriched"	"Detected in many"	6	"Hepatocytes: 225.4;Proximal tubular cells: 163.7"	"Cancer enriched"	"Detected in many"	5	"liver cancer: 73.5"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Group enriched"	"Detected in some"	7	"AF22: 36.7;Hep G2: 120.2;NTERA-2: 68.4;RH-30: 90.7"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"									NA	NA		380000	"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"				"unprognostic (8.02e-2)"	"unprognostic (3.50e-4)"	"unprognostic (3.03e-1)"	"unprognostic (6.25e-3)"	"unprognostic (1.52e-1)"	"unprognostic (5.01e-2)"	"unprognostic (1.95e-3)"	"unprognostic (1.15e-2)"	"unprognostic (2.17e-1)"	"unprognostic (3.45e-1)"	"prognostic favorable (1.49e-4)"	"unprognostic (2.39e-1)"	"unprognostic (3.13e-3)"	"unprognostic (2.58e-3)"	"unprognostic (2.01e-1)"	"unprognostic (2.79e-2)"	"unprognostic (1.22e-1)"	0.4	0.6	14.3	0.6	17.5	0.3	0.3	17.5	15.6	0.7	11.4	3.6	13.6	1.6	24.4	1.8	8.8	3.4	0.4	13.8	15.3	146.0	506.6	1.2	0.9	15.1	16.3	0.9	0.7	1.7	0.8	4.2	14.7	2.0	1.1	4.4	0.5	3.4	0.3	0.7	4.3	2.0	13.0	1.0	0.9	0.3	16.3	0.4	0.2	0.1	0.5	1.3	0.5	14.2	0.0	0.0	36.7	0.3	0.0	0.0	0.6	0.0	0.2	0.0	0.0	0.0	0.3	0.2	0.8	0.0	0.1	0.2	0.6	0.0	0.1	0.5	0.5	0.5	0.2	120.2	0.0	0.2	0.3	0.0	0.0	0.0	0.2	0.2	0.0	0.4	0.0	1.1	0.0	0.2	0.0	0.7	68.4	2.4	0.0	0.3	90.7	2.2	0.0	0.1	11.2	3.8	0.3	0.2	0.5	5.9	0.2	4.4	0.0	0.1	0.2	0.1	4.3	0.9	11.4	0.4	0.0	0.6	3.6	1.0	0.2	0.3	0.3	0.2	0.3	0.1	0.1	0.4	1.8	0.2	0.1	0.8	1.4	0.3	0.1	0.1	0.4	0.3	14.3	17.5	17.5	15.6	13.8	15.3	15.1	16.3	14.7	13.0	16.3	14.2	0.4	0.0	0.6	12.4	1.4	0.3	0.3	0.2	0.0	2.9	0.2	0.3	0.5	5.7	0.1	0.0	4.2	0.2	0.7	0.2	9.8	0.0	1.5	0.2	0.3	0.8	1.2	5.3	0.2	0.2	7.7	0.7	1.5	0.2	5.7	1.3	5.3	225.4	1.2	0.0	0.5	0.0	0.0	6.0	2.1	2.1	0.3	2.2	0.0	1.0	2.2	29.0	0.0	1.0	0.1	0.0	0.0	1.2	0.2	0.3	1.9	163.7	0.0	1.4	0.0	0.7	0.4	0.1	1.0	0.0	0.1	0.4	1.2	0.1	0.1	0.1
PIR		ENSG00000087842	Pirin	O00625	X	15384799-15493564	"Enzymes, Plasma proteins, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 96.1;Syncytiotrophoblasts: 85.6"	"Cancer enhanced"	"Detected in all"		"melanoma: 48.5"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"GAMG: 292.4;HUVEC TERT2: 683.9;SK-MEL-30: 267.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA000697	Approved		Supported	Cytosol		NA	NA		35000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 47: Cytotrophoblasts - Unknown function"	Cytosol		"HPA000697: AB_1079621"	"unprognostic (3.46e-3)"	"prognostic favorable (2.78e-4)"	"unprognostic (4.26e-2)"	"unprognostic (5.62e-3)"	"unprognostic (4.16e-3)"	"unprognostic (2.09e-2)"	"unprognostic (6.70e-3)"	"unprognostic (1.65e-1)"	"unprognostic (1.08e-1)"	"prognostic favorable (4.94e-4)"	"unprognostic (3.78e-2)"	"unprognostic (1.92e-1)"	"prognostic unfavorable (6.11e-7)"	"unprognostic (1.99e-2)"	"unprognostic (8.90e-2)"	"unprognostic (1.03e-1)"	"unprognostic (1.44e-1)"	19.1	19.9	20.2	5.2	23.7	5.7	15.4	23.5	24.3	12.4	21.2	10.0	6.5	11.7	15.3	29.6	13.3	11.4	17.3	18.7	22.9	11.4	21.0	15.4	2.7	23.0	22.6	13.1	3.3	4.9	11.3	10.5	22.8	10.1	6.7	7.9	10.3	14.2	14.7	11.9	8.6	10.4	22.5	20.1	11.9	6.2	22.5	6.2	15.7	6.4	7.1	30.4	17.4	25.7	14.3	76.6	45.0	66.3	26.1	29.0	14.4	4.2	26.5	11.0	24.5	21.5	118.9	0.0	147.2	12.3	292.4	96.7	52.8	21.3	4.0	0.0	11.6	8.4	80.7	63.9	33.4	4.4	29.8	8.3	72.3	41.9	14.4	19.2	683.9	0.0	6.4	19.2	9.4	29.8	3.3	4.1	48.4	62.1	47.7	0.0	8.9	37.9	22.2	136.0	17.2	47.5	36.7	20.5	267.9	76.8	42.4	26.7	43.2	5.9	11.0	28.5	8.7	9.1	39.6	0.3	28.6	15.8	59.8	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	20.2	23.7	23.5	24.3	18.7	22.9	23.0	22.6	22.8	22.5	22.5	25.7	24.5	0.0	4.1	0.0	1.1	8.7	24.3	48.4	10.8	2.8	4.2	4.8	5.8	10.0	19.4	1.8	0.0	96.1	0.0	4.8	9.8	5.9	0.6	59.6	3.8	40.3	11.3	11.6	0.2	2.5	12.8	15.6	15.8	20.0	0.0	21.7	22.9	24.0	22.0	20.2	0.2	3.4	38.7	6.4	3.4	4.0	37.6	4.1	40.9	0.0	11.9	30.8	0.0	0.0	0.0	3.4	1.7	28.6	3.6	18.1	5.9	12.0	38.0	4.8	13.1	8.4	11.3	0.6	3.5	34.5	12.6	85.6	0.6	56.2	4.3	50.9
PLOD1	"LH1, LLH, PLOD"	ENSG00000083444	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1"	Q02809	1	11934205-11975538	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"	"Disease variant, Ehlers-Danlos syndrome"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Extravillous trophoblasts: 236.8;Sertoli cells: 105.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA049137, HPA055799"	Uncertain		Uncertain	Nucleoplasm,Vesicles	"Intracellular and membrane"	NA	NA		3600000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 15: Liver - Metabolism"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 38: Extravillous trophoblasts - Unknown function"	Vesicles	Nucleoplasm	"HPA049137: AB_2680649, HPA055799: AB_2682924"	"unprognostic (1.00e-1)"	"unprognostic (2.69e-3)"	"unprognostic (9.21e-3)"	"unprognostic (5.43e-2)"	"unprognostic (7.53e-3)"	"unprognostic (1.12e-2)"	"prognostic unfavorable (2.79e-4)"	"unprognostic (1.13e-3)"	"unprognostic (1.23e-1)"	"unprognostic (1.79e-1)"	"unprognostic (4.15e-3)"	"unprognostic (2.32e-1)"	"prognostic unfavorable (1.91e-12)"	"unprognostic (2.79e-1)"	"unprognostic (7.12e-2)"	"unprognostic (5.92e-2)"	"prognostic unfavorable (2.43e-4)"	58.1	34.6	46.3	35.2	51.2	16.1	41.2	48.6	56.6	65.4	46.4	47.3	37.7	65.0	30.5	21.3	51.1	42.0	71.2	44.5	47.4	45.5	78.1	44.4	15.4	49.6	50.8	54.4	39.0	36.9	29.6	83.8	52.4	34.7	23.2	10.6	75.9	40.6	40.5	27.2	35.6	78.4	44.8	31.5	35.5	11.6	52.2	7.9	34.9	41.6	12.9	42.4	36.0	53.1	112.5	91.4	51.3	239.7	343.4	190.6	39.0	330.4	436.1	170.4	287.1	105.2	71.5	63.1	339.5	367.3	125.9	93.4	75.6	115.6	115.6	66.2	78.3	34.0	136.6	137.3	212.5	21.9	162.7	234.0	59.7	206.2	81.9	573.3	305.0	14.8	97.6	30.9	180.2	71.1	5.7	58.6	22.9	115.4	131.6	25.8	100.0	141.0	98.7	24.3	19.2	77.7	137.3	97.4	164.8	80.4	48.3	55.9	298.7	190.1	141.6	236.3	161.9	71.4	123.7	38.7	425.1	75.5	316.8	0.0	40.3	2.0	17.3	34.4	3.1	1.7	3.0	8.4	32.7	3.4	1.2	6.4	35.5	5.4	32.3	4.9	2.0	22.6	46.3	51.2	48.6	56.6	44.5	47.4	49.6	50.8	52.4	44.8	52.2	53.1	19.4	0.0	7.9	9.4	3.7	7.0	8.0	22.8	8.0	5.7	17.9	17.5	18.3	8.6	8.6	11.0	2.1	39.7	8.7	14.8	3.9	30.3	1.0	11.0	62.2	33.9	8.4	3.0	4.2	9.8	236.8	47.5	17.3	24.8	0.0	20.4	36.8	37.1	46.3	6.7	5.8	12.5	4.1	26.5	8.3	2.4	44.4	16.3	10.6	15.9	17.9	7.9	15.5	3.0	9.8	22.4	15.4	24.5	19.4	8.0	41.5	16.7	4.5	3.1	105.2	77.2	47.3	0.5	3.3	7.4	5.1	33.7	5.5	37.1	16.6	3.9
PLOD2	LH2	ENSG00000152952	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2"	O00469	3	146069440-146163653	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"		"Dioxygenase, Oxidoreductase"	"Disease variant, Osteogenesis imperfecta"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 130.9;Basal respiratory cells: 115.1;Distal enterocytes: 143.7;Extravillous trophoblasts: 130.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"HBF TERT88: 636.0;hTERT-RPE1: 723.8;U-87 MG: 566.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025898, HPA069126"	Approved		Uncertain	Nucleoli,Cytosol	"Intracellular and membrane"	NA	NA		21000		"Cluster 86: Liver & Placenta - Transport via ER"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 33: Fibroblasts - ECM organization"	"Nucleoli, Cytosol"		"CAB025898: , HPA069126: "	"unprognostic (8.68e-2)"	"prognostic unfavorable (1.97e-4)"	"unprognostic (2.23e-1)"	"unprognostic (2.15e-1)"	"unprognostic (1.34e-2)"	"unprognostic (1.29e-3)"	"prognostic unfavorable (7.64e-10)"	"prognostic unfavorable (1.42e-4)"	"unprognostic (2.97e-2)"	"unprognostic (3.36e-2)"	"unprognostic (6.27e-3)"	"unprognostic (2.24e-1)"	"prognostic unfavorable (4.99e-11)"	"prognostic unfavorable (2.83e-4)"	"unprognostic (6.07e-2)"	"unprognostic (4.06e-2)"	"unprognostic (4.41e-3)"	63.1	20.1	13.4	35.6	14.5	1.1	18.6	15.1	17.2	10.2	19.4	36.2	42.2	23.5	13.4	18.2	11.4	41.5	22.1	13.3	15.1	26.1	57.3	12.9	3.8	23.1	18.1	20.5	18.7	16.5	7.9	80.6	16.3	13.2	29.9	56.6	9.5	16.2	3.0	3.9	35.0	46.8	17.8	5.4	20.1	8.5	20.6	10.5	90.0	3.9	5.5	25.7	10.0	17.6	134.5	94.3	29.0	9.5	102.5	109.6	73.2	465.5	141.6	247.7	463.0	7.2	13.4	0.0	88.8	79.5	113.1	27.8	34.0	400.5	636.0	0.6	53.5	33.3	84.3	66.9	262.5	0.1	0.6	192.9	56.5	215.2	104.1	723.8	347.7	0.1	45.1	1.8	441.6	48.8	0.3	0.6	18.5	0.3	40.0	0.2	19.2	0.6	105.0	6.5	14.5	0.5	370.3	39.4	39.9	135.1	107.5	4.2	440.4	304.2	92.2	97.8	280.7	138.9	20.9	0.5	566.5	0.4	55.6	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.3	13.4	14.5	15.1	17.2	13.3	15.1	23.1	18.1	16.3	17.8	20.6	17.6	29.1	16.0	11.4	130.9	0.4	7.0	6.4	115.1	30.1	17.1	23.7	10.2	14.3	44.3	47.0	27.6	35.5	9.2	0.3	143.7	9.8	64.5	0.5	35.4	13.8	24.3	19.8	4.6	22.8	53.1	130.6	68.1	19.9	38.7	0.0	42.7	21.0	65.2	5.1	0.0	46.4	19.5	22.4	1.0	2.5	1.2	13.1	3.0	14.2	21.5	0.7	53.8	0.0	64.3	6.0	82.4	48.8	4.9	1.3	8.9	50.5	8.2	33.0	24.7	19.7	36.9	47.2	11.0	18.0	27.5	5.5	18.7	1.0	24.5	25.1	5.6
PLOD3	LH3	ENSG00000106397	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3"	O60568	7	101205977-101218420	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins"		"Dioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Cancer enhanced"	"Detected in all"		"melanoma: 115.2"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Group enriched"	"Detected in all"	4	"dendritic cells: 20.3;monocytes: 22.5;T-cells: 12.6"	"Cell line enhanced"	"Detected in all"		"Karpas-707: 695.6;WM-115: 680.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001236	Uncertain				"Secreted to extracellular matrix"	NA	NA		1600000	"Cluster 39: Non-specific - mRNA processing"	"Cluster 15: Liver - Metabolism"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 38: Extravillous trophoblasts - Unknown function"			"HPA001236: AB_1855474"	"unprognostic (1.15e-1)"	"prognostic unfavorable (1.91e-5)"	"prognostic unfavorable (3.26e-4)"	"unprognostic (1.39e-1)"	"unprognostic (2.76e-3)"	"unprognostic (1.04e-2)"	"unprognostic (6.26e-3)"	"unprognostic (1.11e-3)"	"unprognostic (8.00e-3)"	"unprognostic (1.18e-2)"	"unprognostic (4.18e-2)"	"unprognostic (1.66e-1)"	"unprognostic (1.21e-3)"	"unprognostic (1.68e-1)"	"unprognostic (1.54e-1)"	"unprognostic (8.52e-3)"	"unprognostic (9.87e-2)"	41.9	27.3	43.6	22.9	53.2	19.6	32.8	54.9	58.5	33.3	46.8	37.8	25.7	38.9	11.7	12.2	32.5	18.8	42.6	43.6	46.3	36.3	54.1	37.5	14.6	61.1	52.3	26.3	41.8	21.5	27.1	35.0	58.9	24.2	15.3	3.9	19.4	18.6	15.3	19.1	35.9	26.0	49.4	35.3	30.0	12.9	51.7	8.0	25.3	11.8	7.5	35.2	25.2	71.9	71.7	62.4	27.1	168.2	116.2	83.9	51.4	125.5	135.9	122.7	88.6	98.0	89.0	5.6	140.2	211.4	100.7	83.0	50.0	72.0	31.2	37.8	23.8	7.2	70.7	97.3	157.6	31.5	57.4	90.8	67.6	71.6	55.4	120.2	110.9	4.6	68.4	695.6	84.2	194.5	3.4	72.1	53.5	120.5	94.9	21.8	35.1	108.3	42.0	19.1	21.2	116.0	81.1	116.2	288.1	66.8	21.9	105.2	100.5	188.1	94.9	228.1	155.0	38.5	75.9	5.2	112.4	74.2	680.2	0.0	18.1	4.4	12.6	21.8	10.9	3.7	9.3	8.3	16.5	2.2	4.1	4.5	1.8	3.6	22.5	20.3	6.7	9.5	43.6	53.2	54.9	58.5	43.6	46.3	61.1	52.3	58.9	49.4	51.7	71.9	34.1	22.4	8.7	11.1	9.7	8.9	10.8	18.9	8.0	5.7	8.1	9.1	16.1	21.5	8.7	25.8	14.6	20.4	22.0	37.6	1.9	40.2	0.6	10.8	29.9	28.5	16.2	19.1	11.9	31.6	71.6	34.2	17.9	20.5	19.7	25.9	26.7	18.3	50.1	8.4	10.8	18.0	4.1	23.3	18.3	2.1	26.1	23.2	62.2	4.7	18.9	7.7	12.3	10.1	33.4	36.1	37.8	14.7	19.7	8.0	45.8	8.8	9.3	7.3	19.7	14.3	29.8	8.9	12.4	1.9	4.8	18.9	12.5	18.4	27.3	5.2
PNPO	PDXPO	ENSG00000108439	"Pyridoxamine 5'-phosphate oxidase"	Q9NVS9	17	47941506-47949308	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Pyridoxine biosynthesis"	Oxidoreductase	"Disease variant, Epilepsy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 88.8"	"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 62.6;Hepatocytes: 53.4;Proximal tubular cells: 86.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA023204, HPA027776"	Enhanced		Approved	Nucleoplasm,Cytosol		NA	NA		450000	"Cluster 39: Non-specific - mRNA processing"	"Cluster 15: Liver - Metabolism"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	"Nucleoplasm, Cytosol"		"HPA023204: AB_1855506, HPA027776: AB_10601246"	"unprognostic (1.88e-2)"	"unprognostic (1.17e-1)"	"unprognostic (1.17e-1)"	"unprognostic (1.07e-1)"	"unprognostic (9.25e-2)"	"unprognostic (2.39e-2)"	"unprognostic (1.23e-2)"	"unprognostic (1.41e-1)"	"unprognostic (2.62e-1)"	"unprognostic (1.97e-2)"	"unprognostic (6.65e-2)"	"unprognostic (8.34e-2)"	"unprognostic (2.02e-3)"	"unprognostic (7.47e-3)"	"unprognostic (8.75e-2)"	"unprognostic (3.34e-2)"	"unprognostic (2.74e-1)"	7.3	15.8	16.5	6.2	15.9	3.5	10.6	16.7	22.0	7.0	12.9	8.8	10.2	5.0	11.6	10.7	10.1	6.6	13.2	16.0	21.9	35.1	88.8	6.4	6.9	19.1	21.2	5.8	10.9	26.6	9.2	7.0	20.6	8.0	8.6	5.4	10.4	7.8	21.1	6.7	9.6	6.1	16.5	7.2	8.6	6.6	20.6	5.8	17.8	19.6	7.7	6.7	7.3	14.3	37.9	30.9	2.4	5.8	15.3	11.7	0.0	12.2	7.7	14.0	11.9	51.1	27.6	35.2	57.4	12.7	5.5	22.0	19.4	34.7	20.3	43.4	16.4	24.6	13.9	53.6	16.3	22.6	16.6	15.4	26.9	25.8	32.7	13.1	18.0	26.1	24.4	12.2	16.5	28.3	25.3	7.8	4.5	37.4	37.1	18.8	10.4	26.2	40.2	19.5	12.1	9.5	11.2	18.6	10.7	8.5	32.4	9.1	19.1	22.6	12.8	22.2	26.2	27.8	34.0	19.0	18.4	19.2	11.7	2.5	12.3	2.8	7.2	17.7	8.2	6.7	6.3	7.6	13.5	5.3	8.2	8.1	1.1	7.9	11.9	9.8	7.0	10.3	16.5	15.9	16.7	22.0	16.0	21.9	19.1	21.2	20.6	16.5	20.6	14.3	7.6	12.8	13.9	7.5	3.9	1.5	6.7	5.0	5.7	1.1	16.2	14.4	1.9	18.6	6.8	12.9	4.2	8.4	7.8	7.3	62.6	18.2	0.8	11.2	6.4	5.9	3.6	7.4	4.2	15.6	1.9	5.3	4.6	13.3	12.7	8.8	6.4	53.4	17.2	3.3	6.2	11.6	2.0	11.4	2.4	0.9	9.9	10.6	1.8	2.8	8.6	7.1	3.1	2.5	3.2	15.0	8.9	6.0	4.9	9.0	20.2	86.3	5.9	1.9	0.0	4.1	3.8	0.7	1.3	7.2	2.3	6.3	4.7	19.5	15.4	5.0
POR	"CYPOR, FLJ26468"	ENSG00000127948	"Cytochrome p450 oxidoreductase"	P16435	7	75899200-75986855	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"		Oxidoreductase	"Congenital adrenal hyperplasia, Craniosynostosis, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 313.3"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 489.2;Proximal enterocytes: 274.2;Theca cells: 647.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-BR-3: 328.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004372, HPA010136"	Enhanced		Approved	Nucleoplasm,Vesicles,Cytosol		NA	NA		12000	"Cluster 5: Granulocytes - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"	"Nucleoplasm, Vesicles"	Cytosol	"CAB004372: AB_627391, HPA010136: AB_1079657"	"unprognostic (1.89e-1)"	"unprognostic (1.53e-1)"	"unprognostic (2.81e-3)"	"unprognostic (8.67e-2)"	"prognostic unfavorable (8.54e-4)"	"unprognostic (1.65e-1)"	"unprognostic (1.17e-2)"	"unprognostic (4.32e-2)"	"unprognostic (1.69e-2)"	"unprognostic (1.46e-1)"	"unprognostic (1.22e-1)"	"unprognostic (2.58e-1)"	"unprognostic (1.11e-1)"	"unprognostic (9.31e-2)"	"unprognostic (1.71e-1)"	"unprognostic (3.94e-2)"	"unprognostic (9.89e-2)"	53.4	197.4	19.9	32.1	20.7	17.9	44.7	14.1	18.6	42.0	15.5	35.9	105.2	32.1	29.4	53.6	50.2	37.0	43.3	20.7	30.2	38.1	313.3	55.0	19.9	22.2	24.5	52.2	44.5	77.6	71.4	46.3	20.9	31.8	21.9	12.7	29.9	113.1	56.2	43.8	92.4	28.2	16.9	43.8	41.5	25.5	34.7	38.0	131.3	68.1	23.2	36.6	42.3	15.3	59.6	133.0	57.0	106.3	212.9	79.8	98.0	24.4	79.3	44.7	62.3	100.7	257.0	56.1	21.9	53.1	151.8	28.3	76.0	38.4	19.6	48.1	57.9	26.0	36.9	189.4	146.5	26.2	45.5	163.9	47.4	59.2	43.2	36.3	42.3	27.1	79.1	24.0	40.8	90.9	29.0	49.4	71.7	92.9	74.8	41.0	37.6	61.1	50.0	72.8	59.3	57.4	65.4	328.4	91.0	32.6	94.0	44.2	38.6	41.7	45.8	63.6	48.7	23.8	38.3	39.0	59.3	39.8	54.9	65.9	42.6	60.4	20.6	39.6	17.1	11.0	17.5	19.4	45.6	11.2	17.1	14.7	53.8	25.9	30.2	12.5	19.3	36.6	19.9	20.7	14.1	18.6	20.7	30.2	22.2	24.5	20.9	16.9	34.7	15.3	34.3	38.5	39.7	23.2	17.1	17.1	29.4	172.3	13.1	31.4	20.5	14.0	10.9	54.3	201.4	73.5	12.5	99.9	26.0	97.7	1.9	65.0	27.6	62.1	28.0	27.1	19.8	11.8	10.1	29.4	95.0	40.1	67.8	46.6	24.7	121.4	32.2	489.2	67.8	15.2	17.1	41.7	124.1	35.2	16.1	9.5	75.8	47.3	12.4	11.2	20.5	25.9	12.3	11.6	8.8	27.9	102.0	112.5	17.0	20.7	274.2	31.7	178.6	23.0	65.7	32.7	46.9	21.3	30.8	18.2	14.6	193.2	25.4	647.6	44.5	45.9
PPOX	"PPO, VP"	ENSG00000143224	"Protoporphyrinogen oxidase"	P50336	1	161166056-161178013	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Heme biosynthesis, Porphyrin biosynthesis"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Erythroid cells: 65.9;Respiratory ciliated cells: 84.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA030123	Uncertain		Approved	Vesicles,Mitochondria,Cytosol		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 49: Ciliated cells - Cilium organization"	Mitochondria	"Vesicles, Cytosol"	"HPA030123: AB_10603987"	"unprognostic (1.17e-1)"	"unprognostic (4.73e-2)"	"unprognostic (9.88e-2)"	"unprognostic (2.13e-2)"	"unprognostic (3.24e-1)"	"unprognostic (1.64e-2)"	"unprognostic (9.58e-3)"	"unprognostic (1.79e-2)"	"unprognostic (9.17e-2)"	"unprognostic (1.17e-1)"	"unprognostic (2.18e-3)"	"unprognostic (7.12e-3)"	"prognostic unfavorable (9.89e-4)"	"unprognostic (6.12e-2)"	"unprognostic (2.23e-1)"	"unprognostic (3.27e-1)"	"unprognostic (1.80e-2)"	9.3	17.1	24.2	3.5	24.5	25.2	10.3	25.2	38.2	14.5	24.7	12.7	3.9	10.9	8.3	8.9	22.0	4.7	13.1	24.4	24.7	15.5	11.5	8.6	5.7	25.0	25.0	13.8	10.8	7.2	13.7	6.5	24.6	13.4	3.9	12.6	8.7	7.7	7.6	11.2	8.5	6.6	25.0	13.6	10.9	6.9	24.0	5.0	11.9	5.6	5.2	11.6	9.6	25.4	10.0	8.0	12.7	8.5	10.4	9.3	3.5	5.9	5.7	7.5	10.3	10.4	9.3	7.4	14.3	5.3	4.1	6.3	9.8	8.8	7.1	4.6	20.3	9.0	18.9	23.9	8.6	3.0	4.6	7.6	11.0	6.3	9.4	9.4	14.7	7.0	22.8	11.2	5.6	9.2	12.0	8.6	8.2	11.2	18.8	13.6	8.2	16.7	15.1	4.2	9.8	14.7	6.6	10.3	12.0	14.6	19.9	9.5	5.7	6.5	7.1	6.5	7.5	19.4	15.3	10.5	6.8	6.0	4.9	6.3	7.2	5.3	10.4	7.6	7.2	9.0	7.8	7.6	10.4	8.2	6.8	6.9	2.9	12.0	5.2	6.6	16.1	7.8	24.2	24.5	25.2	38.2	24.4	24.7	25.0	25.0	24.6	25.0	24.0	25.4	10.9	3.2	13.7	10.4	9.8	12.0	8.3	16.6	9.1	18.0	12.1	14.1	10.1	4.3	15.6	7.3	22.9	21.4	10.6	3.6	21.5	9.5	9.8	39.1	5.9	8.3	6.0	65.9	5.9	5.6	9.4	9.1	5.1	4.6	6.3	12.3	8.9	6.1	9.3	15.2	7.5	7.3	26.4	4.7	8.4	12.1	10.2	8.0	1.8	5.6	8.1	10.4	8.2	9.0	8.9	6.3	3.8	6.8	16.9	3.2	6.6	17.2	84.4	20.9	6.6	9.6	15.6	12.8	9.3	7.2	14.9	10.4	10.6	11.1	7.5	6.2
PRDX1	"NKEFA, PAGA"	ENSG00000117450	"Peroxiredoxin 1"	Q06830	1	45510914-45542732	"Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Antioxidant, Oxidoreductase, Peroxidase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Proximal tubular cells: 2690.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004682, HPA007730"	Approved		Approved	Mitochondria		NA	NA		110000000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 10: Non-specific - Unknown function"	Mitochondria		"CAB004682: AB_437046, HPA007730: AB_1855204"	"unprognostic (1.28e-2)"	"unprognostic (4.64e-1)"	"unprognostic (2.22e-2)"	"unprognostic (3.65e-1)"	"unprognostic (2.38e-1)"	"unprognostic (3.95e-2)"	"prognostic unfavorable (1.17e-5)"	"unprognostic (2.47e-1)"	"unprognostic (1.31e-1)"	"unprognostic (4.68e-2)"	"unprognostic (3.05e-2)"	"unprognostic (2.90e-1)"	"unprognostic (2.39e-2)"	"unprognostic (5.99e-2)"	"unprognostic (2.88e-1)"	"unprognostic (1.24e-1)"	"prognostic unfavorable (2.89e-4)"	277.8	362.9	642.4	290.2	667.1	86.7	454.3	700.7	747.3	314.1	627.0	326.7	501.4	255.3	459.4	945.8	306.3	297.4	542.9	613.0	700.8	785.5	841.2	340.2	371.4	712.1	706.3	255.5	122.7	214.6	210.0	353.3	711.6	256.0	327.1	347.3	348.6	307.2	571.4	296.5	402.1	329.3	713.5	265.8	355.5	143.7	671.4	262.8	802.3	477.7	603.3	393.2	375.3	766.6	1028.1	1743.7	735.2	942.9	828.4	701.9	1459.3	1134.8	1144.1	1183.0	964.3	932.3	429.2	899.1	1125.9	1237.6	1448.6	967.6	1640.2	1101.3	1193.0	696.9	1266.4	678.6	2042.8	2484.7	361.0	793.6	848.9	610.4	813.6	1201.7	283.8	657.7	1409.7	1044.0	1271.8	292.7	1225.2	829.4	1053.7	772.5	2339.8	2241.0	1867.3	1863.6	934.0	1177.7	2211.5	872.4	987.5	495.1	1035.3	2524.2	73.3	2157.3	760.6	631.1	1208.1	474.8	1071.9	1034.4	1541.5	206.1	1220.5	1678.2	791.4	537.9	278.7	469.3	325.6	111.6	155.7	367.1	205.4	253.8	246.8	209.3	293.9	221.6	150.3	166.6	12.1	123.8	407.5	195.9	438.2	416.3	642.4	667.1	700.7	747.3	613.0	700.8	712.1	706.3	711.6	713.5	671.4	766.6	530.7	522.4	259.0	48.3	330.1	607.3	1115.3	1161.1	745.0	161.3	387.0	510.9	54.9	397.5	685.2	617.9	104.3	1258.6	151.5	339.3	946.9	1015.7	19.7	662.7	281.2	437.8	174.5	304.2	15.5	442.8	1773.2	462.0	500.0	435.5	325.3	463.2	326.3	875.2	1467.4	206.9	17.1	295.0	545.3	366.9	980.7	44.2	498.6	534.8	581.7	12.2	545.7	416.4	62.8	24.1	90.5	804.4	384.9	410.7	612.8	1100.9	995.0	2690.9	919.1	402.2	309.0	279.0	982.6	84.5	329.2	1346.9	528.6	1114.9	270.9	499.4	398.8	1462.7
PRDX2	"MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA"	ENSG00000167815	"Peroxiredoxin 2"	P32119	19	12796820-12801800	"Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Antioxidant, Oxidoreductase, Peroxidase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 1316.7;Erythroid cells: 3153.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB008713	Approved					NA	NA		800000000	"Cluster 20: T-cells - T-cell receptor"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 6: Erythroid cells - Oxygen transport"			"CAB008713: AB_1620974"	"unprognostic (1.12e-1)"	"unprognostic (1.98e-3)"	"unprognostic (8.58e-2)"	"unprognostic (4.40e-2)"	"unprognostic (4.56e-2)"	"unprognostic (1.92e-2)"	"unprognostic (2.44e-1)"	"unprognostic (2.59e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.47e-1)"	"unprognostic (3.26e-2)"	"unprognostic (9.18e-2)"	"prognostic favorable (5.66e-11)"	"unprognostic (7.01e-3)"	"unprognostic (2.15e-1)"	"unprognostic (3.51e-2)"	"unprognostic (1.41e-1)"	199.0	622.0	350.8	88.3	366.6	686.7	159.7	408.2	461.5	167.8	365.6	208.1	251.7	178.8	144.5	271.8	153.5	133.9	704.0	369.6	400.0	287.7	310.2	109.1	118.3	407.5	380.4	218.2	201.7	454.5	314.6	87.8	408.2	175.3	141.5	207.1	200.1	124.4	722.9	260.7	201.1	127.0	357.0	118.1	226.6	32.8	399.1	181.3	156.3	847.9	129.2	163.6	171.6	355.5	420.4	1.1	553.9	721.3	79.5	54.2	408.4	189.0	188.0	253.9	143.4	438.1	102.8	122.7	430.9	185.0	30.2	389.5	354.7	309.7	72.9	528.5	561.4	222.6	537.4	665.1	212.4	0.7	1.4	233.6	140.5	191.1	93.0	327.6	238.8	255.3	485.7	187.0	98.7	763.3	500.1	190.2	409.1	289.6	789.4	485.8	0.7	593.0	343.1	450.0	683.8	538.5	449.5	454.9	153.7	100.7	408.0	318.0	105.7	188.2	156.9	526.7	417.7	226.3	242.1	573.5	178.9	75.5	43.8	35.4	170.0	85.6	436.1	129.4	460.6	375.2	589.8	446.2	211.6	288.5	594.7	460.9	22.4	213.2	148.0	124.5	697.4	686.6	350.8	366.6	408.2	461.5	369.6	400.0	407.5	380.4	408.2	357.0	399.1	355.5	192.2	22.4	36.7	39.5	117.5	221.3	255.6	877.7	187.2	317.9	271.2	322.2	37.1	265.9	347.7	279.6	100.1	692.8	83.5	367.4	1316.7	329.5	3.1	138.6	218.5	130.3	333.7	3153.4	31.8	167.2	558.8	204.3	214.6	197.7	47.0	466.0	137.8	489.7	234.0	215.4	50.8	360.7	754.8	63.8	128.8	13.0	293.9	58.7	281.1	23.4	61.4	531.2	56.7	41.7	29.1	179.6	250.6	321.2	263.4	169.3	765.6	1097.9	152.7	373.2	157.8	142.4	273.2	4.8	7.7	368.5	229.4	508.4	144.4	816.6	475.7	243.1
PRDX3	"AOP-1, AOP1, MER5, SP-22"	ENSG00000165672	"Peroxiredoxin 3"	P30048	10	119167720-119178812	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Antioxidant, Oxidoreductase, Peroxidase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 1060.4;Proximal tubular cells: 937.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008656, HPA041488, CAB079909"	Enhanced		Supported	Mitochondria		NA	NA		1600000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria		"CAB008656: AB_1620979, CAB079909: AB_2809998, HPA041488: AB_2677508"	"unprognostic (8.29e-2)"	"unprognostic (1.02e-1)"	"unprognostic (1.26e-2)"	"unprognostic (1.68e-1)"	"unprognostic (1.17e-1)"	"unprognostic (1.72e-3)"	"unprognostic (4.62e-3)"	"unprognostic (2.40e-1)"	"unprognostic (2.06e-1)"	"unprognostic (3.65e-2)"	"unprognostic (1.29e-2)"	"unprognostic (9.48e-2)"	"unprognostic (6.03e-3)"	"unprognostic (2.77e-1)"	"unprognostic (2.77e-1)"	"unprognostic (2.27e-1)"	"unprognostic (1.21e-1)"	165.7	335.3	92.4	96.0	92.6	82.3	138.3	101.3	116.0	103.4	139.2	133.3	137.8	87.0	120.8	83.3	116.7	88.0	278.2	95.2	104.5	385.7	571.2	74.9	108.4	97.2	97.1	74.9	96.2	223.8	60.0	126.3	99.0	126.7	139.8	52.5	132.1	131.7	376.0	38.0	132.1	130.0	100.4	76.3	97.5	48.3	98.6	98.3	176.7	402.7	104.0	112.8	65.1	102.7	350.6	392.2	234.1	267.3	241.7	259.8	145.9	244.8	414.8	364.5	380.7	303.4	339.9	407.2	208.8	290.8	173.4	155.5	391.5	296.1	408.8	401.5	411.4	183.7	149.7	542.4	252.5	347.8	212.7	306.8	186.4	292.1	269.7	261.2	268.6	245.2	230.0	82.5	338.7	140.2	265.1	292.7	218.9	264.0	229.3	276.5	339.7	281.5	623.8	164.6	103.0	149.2	259.8	346.1	332.2	201.0	179.6	411.5	190.5	118.3	178.1	170.9	323.1	128.0	200.7	327.0	185.7	507.4	107.3	144.4	429.1	246.9	110.5	369.5	142.7	179.9	145.6	134.6	382.1	149.8	149.5	134.0	239.9	132.8	333.9	214.8	205.7	510.2	92.4	92.6	101.3	116.0	95.2	104.5	97.2	97.1	99.0	100.4	98.6	102.7	61.4	48.1	74.5	14.4	65.1	69.8	117.8	274.0	81.4	27.5	145.2	105.2	236.5	131.5	119.0	147.1	10.4	328.4	50.6	84.5	1060.4	124.5	5.0	105.1	76.0	78.3	110.9	132.8	15.4	75.1	212.0	100.8	116.7	77.3	52.6	131.0	73.2	390.0	247.6	40.4	15.4	132.5	221.8	164.2	96.0	10.5	77.3	127.9	133.4	10.3	158.4	76.9	39.1	12.5	18.8	63.8	99.3	101.2	153.7	95.1	176.1	937.8	163.4	24.8	72.3	63.1	105.3	11.2	23.2	146.4	52.6	155.0	56.1	440.0	207.0	119.6
PRDX4	AOE37-2	ENSG00000123131	"Peroxiredoxin 4"	Q13162	X	23664262-23686397	"Cancer-related genes, Enzymes, Predicted intracellular proteins"		"Antioxidant, Oxidoreductase, Peroxidase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	4	"pancreas: 1212.0"	"Cell type enhanced"	"Detected in all"		"Late spermatids: 1007.4;Plasma cells: 810.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008659, CAB027389, CAB047362, HPA067039"	Enhanced		Supported	"Endoplasmic reticulum,Cytosol"	"Intracellular and membrane"	NA	NA		4400000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 25: Pancreas - Digestion"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 55: Plasma cells - Humoral immune response"	"Endoplasmic reticulum"	Cytosol	"CAB008659: AB_1620984, CAB027389: , CAB047362: , HPA067039: "	"unprognostic (3.82e-2)"	"unprognostic (6.05e-2)"	"unprognostic (1.09e-1)"	"unprognostic (6.06e-3)"	"unprognostic (1.64e-1)"	"unprognostic (1.65e-2)"	"unprognostic (1.29e-3)"	"unprognostic (1.08e-1)"	"unprognostic (8.32e-2)"	"unprognostic (3.75e-2)"	"unprognostic (2.97e-1)"	"unprognostic (1.79e-1)"	"prognostic unfavorable (1.33e-6)"	"unprognostic (7.44e-2)"	"unprognostic (1.29e-1)"	"unprognostic (3.56e-1)"	"unprognostic (4.10e-2)"	85.7	84.6	25.2	53.9	27.4	34.3	74.9	28.7	36.6	82.3	40.2	72.7	64.0	68.1	19.5	62.5	66.1	64.7	108.6	24.7	28.7	41.8	277.2	47.1	58.7	30.6	26.8	81.2	1212.0	69.2	93.8	96.2	29.6	59.9	78.8	30.2	124.9	63.2	43.7	47.8	51.3	62.9	29.7	71.9	93.5	121.4	27.5	26.5	49.5	25.4	67.1	68.9	55.7	36.8	176.4	238.2	94.5	191.1	523.9	266.6	138.0	229.6	249.2	204.9	297.5	251.4	214.3	150.0	106.1	299.0	233.6	206.5	279.8	142.6	193.8	92.5	551.5	105.8	187.8	322.1	215.9	138.4	96.9	283.6	182.6	197.7	193.5	213.8	262.0	48.4	209.7	535.4	192.8	262.3	70.3	214.5	339.8	329.5	344.9	97.2	244.3	861.2	181.0	60.5	143.8	121.7	212.6	248.6	174.9	504.1	263.1	174.4	172.7	145.1	95.1	378.4	176.1	173.8	228.6	161.5	259.9	177.0	211.9	5.9	65.6	6.9	53.8	107.8	67.4	89.9	68.1	57.1	101.6	56.0	48.4	49.7	4.8	83.8	137.8	71.3	74.6	69.8	25.2	27.4	28.7	36.6	24.7	28.7	30.6	26.8	29.6	29.7	27.5	36.8	143.8	57.7	68.2	5.5	132.8	59.8	88.6	277.2	62.0	16.7	98.8	119.0	50.7	107.2	124.0	49.7	8.4	328.7	17.9	34.0	9.8	270.4	402.0	66.5	117.4	96.2	58.7	60.6	2.4	358.8	531.6	162.1	65.2	117.6	43.1	206.7	92.1	539.5	173.4	11.8	3.3	151.6	187.2	54.2	55.1	1007.4	252.5	47.1	199.3	1.9	75.2	55.0	27.8	8.5	7.3	241.4	44.1	144.0	810.1	174.6	61.2	54.2	89.9	21.7	144.7	79.2	185.3	258.2	251.7	83.3	52.1	258.6	42.0	311.8	115.7	73.1
PRDX5	"ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10"	ENSG00000126432	"Peroxiredoxin 5"	P30044	11	64318121-64321811	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Antioxidant, Oxidoreductase, Peroxidase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Respiratory ciliated cells: 2430.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008661, HPA037915, HPA037916"	Enhanced		Supported	Mitochondria		NA	NA		6900000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"	Mitochondria		"CAB008661: AB_1620988, HPA037915: AB_2675735, HPA037916: AB_2675736"	"unprognostic (2.75e-1)"	"unprognostic (4.08e-1)"	"unprognostic (1.33e-1)"	"unprognostic (1.46e-1)"	"unprognostic (9.43e-2)"	"unprognostic (6.71e-3)"	"unprognostic (1.08e-3)"	"unprognostic (3.11e-1)"	"unprognostic (9.30e-2)"	"unprognostic (1.07e-3)"	"unprognostic (1.57e-2)"	"unprognostic (2.20e-1)"	"prognostic favorable (1.24e-5)"	"unprognostic (8.19e-2)"	"unprognostic (2.30e-1)"	"unprognostic (9.63e-2)"	"unprognostic (5.03e-2)"	181.8	400.3	346.0	112.7	342.6	285.7	170.1	375.9	429.4	227.2	480.2	346.6	213.3	153.7	176.6	448.5	400.3	120.7	467.4	340.4	384.6	377.1	280.3	217.2	110.1	382.8	373.3	246.0	224.9	254.5	313.3	164.1	387.0	165.5	299.6	109.0	286.2	164.4	504.0	181.1	226.1	97.1	365.2	162.9	313.9	150.1	377.8	167.7	354.5	439.6	137.8	192.5	244.8	346.4	225.3	453.4	267.9	444.5	284.3	424.4	308.5	274.9	442.3	199.8	247.4	332.9	451.8	329.2	467.0	447.4	712.6	503.5	253.3	589.4	125.8	456.6	200.8	333.3	728.8	386.3	581.0	127.8	271.3	432.4	757.2	334.9	337.8	387.6	308.4	380.6	191.5	755.6	285.5	572.0	220.9	547.8	402.6	356.5	573.9	210.9	274.5	1178.8	760.1	442.9	224.7	424.9	230.8	506.8	818.8	254.3	370.5	283.3	298.3	281.8	258.6	326.7	123.1	383.1	490.8	392.4	340.7	253.7	223.6	703.9	465.4	630.7	251.0	432.9	218.3	393.5	229.0	205.1	369.8	409.0	224.5	225.9	802.3	368.5	399.0	487.9	297.1	639.6	346.0	342.6	375.9	429.4	340.4	384.6	382.8	373.3	387.0	365.2	377.8	346.4	213.7	266.0	463.4	17.6	182.1	326.5	760.2	1591.9	405.2	159.0	266.2	435.9	617.6	371.8	931.2	450.6	70.9	1122.2	185.8	846.1	1612.1	788.4	79.6	865.2	221.3	204.7	801.9	200.6	12.4	1039.2	1144.0	296.1	365.4	285.9	104.7	299.8	205.6	405.2	476.9	92.5	14.0	1041.6	1072.1	206.5	261.0	294.9	279.0	210.8	435.8	8.4	339.7	309.6	278.1	14.1	15.3	1487.3	641.3	226.8	288.9	401.3	922.4	1468.5	2430.7	150.3	197.2	176.2	433.1	150.2	333.9	482.8	257.7	978.9	165.2	713.3	1231.7	1077.1
PRDX6	"1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX"	ENSG00000117592	"Peroxiredoxin 6"	P30041	1	173477330-173488815	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Lipid degradation, Lipid metabolism"	"Antioxidant, Hydrolase, Multifunctional enzyme, Oxidoreductase, Peroxidase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal enterocytes: 1315.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006983, CAB008663"	Supported		Supported	"Plasma membrane,Cytosol"		NA	NA		120000000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Plasma membrane, Cytosol"		"CAB008663: AB_1620994, HPA006983: AB_1079595"	"unprognostic (9.92e-2)"	"unprognostic (1.50e-1)"	"unprognostic (3.67e-1)"	"unprognostic (2.99e-3)"	"unprognostic (1.96e-1)"	"prognostic unfavorable (1.23e-5)"	"unprognostic (5.71e-3)"	"unprognostic (2.80e-2)"	"unprognostic (5.27e-3)"	"unprognostic (3.96e-3)"	"unprognostic (3.19e-3)"	"unprognostic (1.59e-1)"	"prognostic unfavorable (9.51e-4)"	"unprognostic (2.50e-1)"	"unprognostic (7.12e-2)"	"unprognostic (1.15e-1)"	"unprognostic (4.73e-3)"	340.7	157.5	169.5	68.3	181.3	100.1	211.2	197.6	210.1	112.3	164.8	189.1	46.4	108.8	206.3	127.9	149.8	71.9	261.8	184.1	196.6	184.4	482.5	116.7	72.2	181.0	198.3	115.5	114.4	217.5	67.4	70.7	187.5	152.1	221.6	53.9	85.6	99.0	563.5	106.6	59.8	160.2	175.8	70.7	135.2	119.1	176.7	70.7	106.0	382.4	79.0	99.5	109.8	185.5	420.3	127.7	204.7	230.9	778.5	372.7	169.5	843.9	284.3	342.7	241.8	243.9	276.4	272.4	256.4	694.2	120.4	239.8	272.0	259.9	279.0	234.0	243.6	179.5	200.0	277.7	425.7	191.3	56.1	301.0	262.6	181.3	256.6	210.8	339.5	106.7	405.4	52.8	392.9	86.3	131.7	249.1	456.2	219.8	760.5	154.5	236.6	277.0	518.1	95.4	94.9	173.4	285.0	334.0	199.2	296.3	283.8	262.9	228.2	132.5	149.9	201.8	229.5	76.4	123.2	220.7	159.4	162.3	124.3	36.2	42.5	24.8	29.8	39.8	32.8	32.6	29.8	38.4	53.5	24.4	39.8	47.9	25.2	25.7	36.5	79.7	36.1	58.1	169.5	181.3	197.6	210.1	184.1	196.6	181.0	198.3	187.5	175.8	176.7	185.5	278.1	176.3	170.8	127.3	127.4	235.4	404.1	382.8	209.5	31.9	186.1	250.7	528.6	301.7	228.6	277.7	29.2	714.3	158.6	1315.9	860.8	178.6	237.5	206.9	226.8	191.8	142.1	449.5	13.8	202.3	939.1	307.0	111.6	200.0	348.6	216.6	214.2	1120.2	345.0	45.4	13.2	257.4	205.4	164.3	161.0	667.5	340.5	227.1	183.2	17.8	212.9	462.5	83.4	12.5	15.4	147.2	663.4	416.8	176.4	427.1	264.4	827.3	209.1	52.0	184.1	185.7	253.8	123.5	76.8	305.9	264.1	963.5	157.7	512.5	303.6	308.9
PRODH	"HSPOX2, PIG6, PRODH1, PRODH2, TP53I6"	ENSG00000100033	"Proline dehydrogenase 1"	O43272	22	18912777-18936553	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Proline metabolism"	Oxidoreductase	"Disease variant, Schizophrenia"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"skeletal muscle: 49.2;skin 1: 39.8"	"Cell type enriched"	"Detected in some"	7	"Astrocytes: 183.1"	"Cancer enhanced"	"Detected in many"		"testis cancer: 11.0"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	12	"OE19: 91.3;RPTEC TERT1: 35.9"									HPA020361	Approved		Approved	Nucleoplasm,Vesicles,Mitochondria		NA	NA				"Cluster 59: Non-specific - Translation"	"Cluster 21: OE19 - Mitochondria"	"Cluster 64: Astrocytes - Nervous system maintenance"	Mitochondria	"Nucleoplasm, Vesicles"	"HPA020361: AB_10963116"	"unprognostic (2.46e-2)"	"prognostic favorable (1.54e-4)"	"unprognostic (1.40e-1)"	"unprognostic (3.70e-2)"	"unprognostic (3.80e-2)"	"unprognostic (1.20e-1)"	"unprognostic (1.78e-2)"	"unprognostic (1.07e-2)"	"unprognostic (2.49e-2)"	"unprognostic (6.56e-2)"	"unprognostic (3.12e-2)"	"unprognostic (1.61e-2)"	"unprognostic (7.44e-2)"	"unprognostic (1.07e-1)"	"unprognostic (1.21e-1)"	"unprognostic (5.34e-2)"	"unprognostic (3.94e-2)"	7.9	0.7	5.8	0.4	6.4	0.0	8.5	3.1	9.0	5.0	34.0	3.1	5.6	1.5	0.1	11.6	5.8	0.1	18.6	6.5	2.8	16.7	15.6	20.6	0.2	7.3	4.7	0.5	1.4	0.0	5.4	0.2	2.5	3.2	0.3	0.6	4.2	0.2	49.2	39.8	32.5	0.0	3.3	0.5	3.5	1.7	7.6	0.3	7.4	6.2	0.8	4.2	8.5	3.4	0.0	0.8	0.0	0.3	0.9	0.0	0.2	0.0	0.0	0.0	0.0	1.1	0.1	0.0	0.3	0.0	0.0	2.9	3.9	0.2	0.0	0.0	0.2	0.0	0.0	0.0	0.8	0.0	0.0	0.0	2.9	0.0	0.5	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.1	0.6	4.5	91.3	0.0	0.0	0.0	0.4	35.9	0.9	0.1	0.2	0.8	1.4	0.3	5.2	1.4	0.0	0.0	0.0	0.1	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	5.8	6.4	3.1	9.0	6.5	2.8	7.3	4.7	2.5	3.3	7.6	3.4	0.1	16.0	25.6	183.1	0.0	5.1	0.3	13.1	0.0	0.0	0.2	0.1	1.8	0.0	11.5	0.0	0.0	0.0	0.0	2.3	0.0	0.0	0.6	1.2	0.2	0.4	3.5	0.0	0.5	0.0	0.0	0.2	0.0	0.3	0.0	0.0	0.0	0.6	0.0	0.0	1.1	0.0	2.0	0.0	1.5	0.1	0.0	0.1	21.4	17.8	0.0	0.6	0.0	14.1	2.1	0.0	2.3	0.0	0.0	0.0	8.0	0.1	21.0	0.1	0.0	1.1	0.6	0.2	0.4	1.0	15.2	0.0	0.3	0.0	1.6	0.2
PRODH2	HSPOX1	ENSG00000250799	"Proline dehydrogenase 2"	Q9UF12	19	35799988-35813299	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Proline metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	34	"kidney: 140.1;liver: 173.6"	"Group enriched"	"Detected in some"	13	"Hepatocytes: 157.6;Proximal tubular cells: 559.9"	"Cancer enriched"	"Detected in some"	5	"liver cancer: 28.1"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	19	"Hep G2: 33.4"	"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			HPA051287	Approved		Approved	Nucleoplasm,Cytosol		NA	NA				"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Nucleoplasm	Cytosol	"HPA051287: AB_2681420"							"unprognostic (2.58e-1)"				"unprognostic (3.41e-3)"		"unprognostic (2.75e-2)"	"unprognostic (7.03e-2)"	"unprognostic (1.73e-1)"			0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	140.1	173.6	0.0	0.4	0.0	0.0	0.0	4.5	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.1	1.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2	0.0	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	33.4	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	3.8	0.1	0.0	0.0	0.0	1.2	0.0	0.0	0.9	1.5	0.0	12.9	0.0	0.0	0.0	0.0	27.4	0.0	2.8	0.3	0.0	0.3	0.0	2.7	0.2	0.0	0.0	0.0	0.0	0.5	0.0	0.0	1.1	157.6	0.1	0.0	0.1	0.0	0.0	4.7	0.0	0.9	0.0	2.9	0.0	0.0	0.0	0.0	0.0	0.5	0.1	0.0	0.0	0.0	0.0	0.0	0.0	559.9	0.0	0.1	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	1.8	0.0	0.0	0.0
PRXL2B	"C1orf93, FAM213B, MGC26818"	ENSG00000157870	"Peroxiredoxin like 2B"	Q8TBF2	1	2586491-2591469	"Enzymes, Predicted intracellular proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in some"		"Adipocytes: 5.5;Cardiomyocytes: 5.0;Endothelial cells: 2.1;Hofbauer cells: 9.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-BR-3: 51.8;U-2197: 46.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA006403	Approved	Approved	Approved	Nucleoplasm,Cytosol		NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 14: B-cells - Humoral immune response"	"Cluster 18: U-2197 - ECM organization"	"Cluster 33: Fibroblasts - ECM organization"	Cytosol	Nucleoplasm	"HPA006403: AB_1853870"	"unprognostic (1.81e-2)"	"unprognostic (2.25e-1)"	"unprognostic (2.03e-1)"	"unprognostic (2.83e-1)"	"unprognostic (1.32e-1)"	"unprognostic (1.52e-1)"	"prognostic unfavorable (1.62e-4)"	"unprognostic (1.20e-1)"	"unprognostic (8.76e-2)"	"unprognostic (3.09e-2)"	"unprognostic (1.24e-3)"	"unprognostic (2.76e-1)"	"prognostic favorable (1.28e-4)"	"unprognostic (5.22e-3)"	"unprognostic (2.03e-1)"	"unprognostic (7.91e-3)"	"unprognostic (2.20e-2)"	8.3	18.6	11.0	4.8	12.0	3.2	9.2	5.5	16.4	9.4	2.3	24.4	18.7	9.3	1.4	12.3	10.9	6.0	6.4	12.1	10.2	15.6	7.0	11.7	5.0	9.4	10.1	6.3	6.8	5.4	8.7	6.7	11.7	10.0	5.9	2.8	7.8	5.6	1.3	7.8	20.5	3.6	7.3	15.2	14.3	6.6	11.1	4.1	8.1	0.7	3.9	11.7	8.1	8.3	15.8	8.7	9.8	9.1	3.8	4.6	1.2	5.4	6.2	13.6	5.6	6.7	18.0	4.2	13.9	9.5	5.4	12.6	8.2	9.5	4.5	11.8	3.8	9.9	6.1	11.3	10.3	5.3	3.0	6.4	5.2	9.8	3.2	6.7	19.0	6.8	13.3	6.4	13.9	7.7	12.2	2.5	10.4	19.8	31.6	14.2	12.8	10.1	14.2	8.3	11.7	18.0	12.2	51.8	16.8	2.2	9.3	2.2	28.1	11.2	12.7	46.3	5.4	5.2	8.1	3.0	11.0	19.9	2.8	1.9	1.5	0.8	2.5	1.5	4.2	1.2	2.8	2.9	1.6	0.9	2.5	3.7	1.1	4.8	1.4	0.7	4.4	2.4	11.0	12.0	5.5	16.4	12.1	10.2	9.4	10.1	11.7	7.3	11.1	8.3	5.5	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	5.0	0.0	0.0	0.0	0.0	0.3	0.8	0.0	0.0	0.0	0.0	0.0	0.0	2.1	0.0	0.0	0.0	0.0	0.7	1.4	0.0	0.0	0.0	0.0	0.0	0.0	9.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.7	0.2	0.0	0.0	0.0
PTGR1	"LTB4DH, ZADH3"	ENSG00000106853	"Prostaglandin reductase 1"	Q14914	9	111549722-111599893	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"intestine: 278.5;liver: 594.1"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 791.5;Proximal enterocytes: 1230.1;Proximal tubular cells: 581.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in single"	6	"plasmacytoid DC: 5.9"	"Lineage enriched"	"Detected in single"	10	"dendritic cells: 5.9"	"Cell line enhanced"	"Detected in many"		"OE19: 909.3"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA036724	Enhanced					NA	NA		2400000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 21: OE19 - Mitochondria"	"Cluster 2: Hepatocytes - Metabolism"			"HPA036724: AB_10670239"	"unprognostic (1.54e-1)"	"unprognostic (2.23e-1)"	"unprognostic (1.10e-2)"	"unprognostic (3.02e-3)"	"unprognostic (8.46e-2)"	"unprognostic (1.02e-3)"	"unprognostic (1.91e-2)"	"unprognostic (1.37e-1)"	"unprognostic (1.30e-1)"	"unprognostic (1.27e-1)"	"unprognostic (1.28e-2)"	"unprognostic (3.48e-1)"	"prognostic favorable (5.53e-4)"	"unprognostic (2.25e-1)"	"unprognostic (2.24e-1)"	"unprognostic (1.31e-2)"	"unprognostic (5.22e-2)"	44.9	87.7	14.6	11.5	16.3	3.0	37.2	15.4	21.6	35.9	16.7	37.4	232.9	32.4	39.1	112.0	71.5	75.3	29.2	22.6	16.0	234.3	594.1	22.1	7.3	13.0	14.4	25.1	16.7	43.9	23.3	15.3	13.4	60.4	33.9	22.6	47.5	31.1	13.0	31.0	278.5	38.1	11.8	7.9	86.0	8.3	16.4	6.4	27.9	29.0	31.6	88.8	44.4	14.4	49.1	207.1	60.6	0.1	220.1	220.4	45.1	79.4	121.8	74.4	81.2	52.9	67.4	0.1	22.9	78.0	153.9	60.7	47.5	83.4	90.3	0.1	15.4	12.5	129.3	279.0	50.4	7.4	25.6	157.3	127.3	99.8	51.1	88.2	201.0	0.0	8.7	0.1	148.5	16.1	0.4	2.0	22.8	909.3	49.8	0.2	17.1	1.4	82.8	152.8	68.4	3.4	98.9	30.0	31.7	59.6	94.6	34.8	161.8	15.4	29.3	169.7	15.0	0.1	0.5	0.3	72.0	0.1	18.1	0.0	0.5	0.0	0.0	0.1	0.1	0.2	0.0	0.0	0.9	0.0	0.0	0.0	0.1	0.0	0.0	5.9	0.0	0.3	14.6	16.3	15.4	21.6	22.6	16.0	13.0	14.4	13.4	11.8	16.4	14.4	28.9	19.2	28.3	16.6	4.3	38.6	57.6	135.5	66.6	18.7	43.7	41.4	37.4	271.7	78.4	141.6	25.0	47.0	6.4	34.4	150.6	73.4	4.2	100.3	36.2	26.1	26.5	18.7	38.4	178.3	32.5	48.6	174.3	89.3	1.3	35.0	49.6	791.5	53.4	0.0	31.2	76.1	59.0	26.8	16.7	3.6	33.2	15.9	35.6	12.2	22.6	47.0	0.0	17.1	16.1	139.6	86.3	39.5	0.5	63.8	1230.1	581.3	80.3	46.4	13.1	17.4	61.8	15.2	5.3	242.9	30.5	20.5	5.8	46.8	145.9	156.5
PTGR2	"FLJ39091, ZADH1"	ENSG00000140043	"Prostaglandin reductase 2"	Q8N8N7	14	73851844-73886827	"Enzymes, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 43.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"basophil: 6.7"	"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"T-47d: 41.9"									HPA001125	Approved		Approved	Vesicles		NA	NA		36000	"Cluster 34: Basophils - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 6: T47d - Mammary gland"	"Cluster 39: Non-specific - Basic cellular processes"	Vesicles		"HPA001125: AB_2666207"	"unprognostic (3.82e-2)"	"unprognostic (2.79e-2)"	"unprognostic (6.05e-2)"	"unprognostic (3.26e-1)"	"unprognostic (2.28e-1)"	"unprognostic (1.40e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.96e-2)"	"unprognostic (2.80e-1)"	"unprognostic (8.10e-3)"	"unprognostic (6.99e-3)"	"unprognostic (5.96e-1)"	"prognostic favorable (4.55e-12)"	"unprognostic (4.42e-2)"	"unprognostic (1.03e-1)"	"unprognostic (1.33e-1)"	"unprognostic (7.24e-2)"	6.9	12.2	10.4	2.8	11.5	0.9	9.1	11.1	12.1	4.8	11.6	7.2	12.1	4.6	17.2	5.0	12.0	5.2	27.1	9.9	11.7	18.9	19.1	5.6	3.1	11.8	11.9	7.4	5.3	10.6	7.6	2.4	12.1	9.1	5.7	10.7	6.7	5.4	32.8	6.9	8.9	2.6	11.3	3.4	6.2	6.2	10.6	3.0	12.6	32.1	2.6	4.2	4.1	13.9	8.9	11.9	9.6	4.7	7.6	16.3	7.6	3.0	4.1	3.6	5.6	6.8	21.2	0.9	6.8	3.0	8.4	8.8	8.7	6.5	6.6	6.7	4.1	6.2	5.5	3.0	3.8	2.3	2.2	7.7	15.1	5.5	4.4	7.8	1.8	6.1	8.3	1.8	8.2	12.7	6.2	5.9	10.7	11.9	11.6	7.6	3.7	1.5	19.7	8.6	12.7	11.0	7.7	8.1	9.8	9.1	41.9	3.7	2.7	5.3	10.0	3.9	6.6	10.2	4.7	2.8	8.3	5.5	7.2	6.7	1.1	0.9	0.6	0.4	0.6	1.0	1.1	0.5	1.3	1.0	1.8	1.5	0.8	1.3	1.2	1.5	1.1	1.0	10.4	11.5	11.1	12.1	9.9	11.7	11.8	11.9	12.1	11.3	10.6	13.9	4.5	19.2	13.0	10.7	2.9	6.8	12.8	16.7	6.2	8.9	8.4	5.5	43.2	8.6	12.9	18.4	14.6	6.3	2.0	8.6	25.4	11.7	2.4	21.5	5.8	5.2	4.8	4.2	8.0	8.7	2.5	6.1	5.1	7.3	3.8	9.3	3.3	14.3	7.4	33.7	10.3	10.0	10.2	5.5	3.1	2.0	7.2	4.3	8.8	5.6	4.0	22.3	6.2	7.1	20.4	8.7	11.1	6.8	2.9	7.2	24.8	18.4	31.6	20.8	6.6	9.9	6.1	42.1	18.8	3.5	6.7	4.0	2.9	17.3	11.7	7.7
PTGS1	"COX1, PGHS-1, PTGHS"	ENSG00000095303	"Prostaglandin-endoperoxide synthase 1"	P23219	9	122370530-122395703	"Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism"	"Dioxygenase, Oxidoreductase, Peroxidase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 108.3;skin 1: 152.5;urinary bladder: 175.0"	"Cell type enhanced"	"Detected in many"		"Endometrial ciliated cells: 109.9;Glandular and luminal cells: 191.9;granulocytes: 208.0;Hepatic stellate cells: 61.8;Macrophages: 55.3;Suprabasal keratinocytes: 58.7"	"Cancer enhanced"	"Detected in all"		"ovarian cancer: 53.4"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"basophil: 28.9"	"Group enriched"	"Detected in many"	6	"dendritic cells: 20.0;granulocytes: 28.9;monocytes: 13.1"	"Cell line enhanced"	"Detected in many"		"ASC diff: 113.7;ASC TERT1: 89.5;BJ: 115.2;BJ hTERT+: 156.0;HEL: 73.6;HMC-1: 298.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA002834, CAB020315"	Enhanced		Supported	"Golgi apparatus,Vesicles"	"Intracellular and membrane"	NA	NA		2100000	"Cluster 2: Granulocytes - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 44: Endometrium - Transcription"	"Golgi apparatus"	Vesicles	"CAB020315: , HPA002834: AB_1079711"	"unprognostic (4.20e-1)"	"unprognostic (6.23e-2)"	"unprognostic (1.08e-2)"	"unprognostic (2.27e-2)"	"unprognostic (5.88e-2)"	"unprognostic (2.00e-2)"	"unprognostic (1.22e-3)"	"unprognostic (3.32e-1)"	"unprognostic (2.24e-1)"	"unprognostic (3.16e-2)"	"unprognostic (1.23e-1)"	"unprognostic (1.46e-1)"	"prognostic unfavorable (8.68e-4)"	"unprognostic (4.03e-2)"	"unprognostic (1.78e-2)"	"unprognostic (2.08e-1)"	"prognostic unfavorable (9.35e-4)"	12.8	2.9	3.1	10.5	3.2	9.0	6.7	4.2	4.8	5.8	5.5	108.3	10.8	6.1	2.2	67.3	43.2	9.6	12.6	7.4	5.5	9.3	3.0	11.3	4.6	6.5	5.2	2.0	1.8	2.0	4.8	2.2	6.3	21.1	24.2	0.7	4.3	6.1	2.1	152.5	17.7	16.1	6.7	8.0	20.5	0.9	7.0	2.2	3.2	4.0	11.6	175.0	15.9	11.9	0.3	0.5	0.4	0.0	113.7	89.5	0.0	115.2	156.0	1.0	1.1	0.0	0.2	4.2	5.4	19.7	0.3	7.1	0.4	10.5	0.9	0.0	0.2	73.6	0.6	0.0	32.9	5.2	298.4	46.1	1.2	5.7	0.3	0.0	42.3	0.1	0.1	0.3	2.3	0.0	0.2	6.6	1.6	0.0	0.5	0.3	1.4	8.6	14.7	0.0	0.5	0.6	0.6	9.5	0.2	0.5	0.3	8.4	1.0	0.7	0.6	1.7	0.1	0.3	0.2	0.0	0.4	31.6	0.3	28.9	12.1	23.3	0.0	13.1	0.0	2.4	0.0	0.0	20.0	3.5	0.1	0.0	5.2	2.8	10.2	1.4	0.2	21.9	3.1	3.2	4.2	4.8	7.4	5.5	6.5	5.2	6.3	6.7	7.0	11.9	0.9	0.0	6.6	0.0	5.9	9.9	2.6	7.7	0.0	0.1	1.1	1.4	1.6	4.3	2.2	42.3	0.0	0.1	0.2	0.1	0.0	0.6	0.1	109.9	10.4	24.7	1.8	18.7	0.8	0.5	0.3	10.7	2.0	191.9	208.0	0.1	61.8	0.8	26.1	0.0	0.5	0.6	4.1	15.5	20.7	0.3	1.5	55.3	3.6	16.9	11.7	0.0	7.2	1.0	0.1	0.6	0.6	0.0	0.3	2.8	0.0	0.0	0.8	0.1	0.0	1.4	3.6	0.0	0.2	18.2	58.7	0.4	3.4	0.1	1.0	0.8
PTGS2	COX2	ENSG00000073756	"Prostaglandin-endoperoxide synthase 2"	P35354	1	186671791-186680922	"Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism"	"Dioxygenase, Oxidoreductase, Peroxidase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 116.7;seminal vesicle: 127.4;urinary bladder: 162.5"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 342.9;Fibroblasts: 270.7;granulocytes: 347.6;Langerhans cells: 305.6;Macrophages: 173.1;Urothelial cells: 151.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in single"	16	"neutrophil: 11.7"	"Lineage enriched"	"Detected in single"	16	"granulocytes: 11.7"	"Cell line enriched"	"Detected in many"	4	"BJ hTERT+: 405.5"	"Region enhanced"	"Detected in many"		"hippocampal formation: 15.1"	"Low region specificity"	"Detected in many"			"CAB000113, HPA001335"	Enhanced		Approved	"Endoplasmic reticulum,Vesicles"	"Intracellular and membrane"	NA	NA			"Cluster 50: Neutrophils - Cellular senescence"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 41: Macrophages - Immune response"	"Endoplasmic reticulum, Vesicles"		"CAB000113: , HPA001335: AB_1079712"	"unprognostic (1.36e-3)"	"unprognostic (9.97e-3)"	"unprognostic (3.97e-2)"	"unprognostic (3.31e-2)"	"unprognostic (1.55e-1)"	"unprognostic (1.11e-1)"	"unprognostic (5.96e-2)"	"unprognostic (9.50e-2)"	"unprognostic (9.03e-3)"	"unprognostic (2.81e-1)"	"unprognostic (3.24e-2)"	"unprognostic (3.07e-2)"	"prognostic unfavorable (9.79e-4)"	"unprognostic (8.04e-3)"	"unprognostic (4.38e-2)"	"unprognostic (8.89e-2)"	"unprognostic (3.74e-2)"	17.0	7.9	1.4	13.9	2.5	116.7	3.0	1.1	4.1	62.2	2.7	14.9	2.6	8.9	0.7	6.9	5.1	31.6	11.7	1.9	1.4	10.2	8.0	34.3	8.9	2.0	1.6	2.6	2.2	5.6	3.1	8.4	1.5	25.0	9.9	0.3	1.2	127.4	0.4	1.6	3.6	12.2	1.9	2.8	14.8	0.2	1.8	5.2	3.2	6.5	0.6	162.5	2.2	2.6	0.0	21.8	0.1	0.0	2.5	2.1	0.0	93.4	405.5	0.6	3.6	15.0	17.2	0.0	0.0	0.1	2.5	12.2	0.0	7.6	1.3	0.0	0.0	0.8	2.2	0.0	13.2	0.0	0.2	0.8	2.7	11.3	28.7	1.0	4.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	3.8	0.0	0.0	0.0	0.0	0.0	5.5	1.5	0.0	1.0	0.0	0.9	2.7	0.0	0.1	1.5	19.3	0.6	13.5	0.6	0.2	0.0	0.0	27.7	0.4	2.3	0.0	0.3	0.2	0.0	0.7	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	11.7	0.0	0.4	0.0	0.0	0.0	1.4	2.5	1.1	4.1	1.9	1.4	2.0	1.6	1.5	1.9	1.8	2.6	5.2	342.9	77.7	0.0	7.4	118.8	59.1	72.8	12.5	0.0	2.6	12.8	2.5	0.0	79.7	0.0	0.0	0.2	4.2	0.3	0.0	0.8	0.2	50.0	9.9	31.1	1.2	3.6	3.8	0.2	0.3	270.7	2.0	98.9	347.6	3.8	13.6	0.2	12.1	0.0	1.0	1.0	8.2	21.0	305.6	0.0	0.0	173.1	35.6	3.7	3.4	0.1	0.0	0.0	0.1	4.9	0.1	0.0	2.0	122.6	0.2	0.3	13.1	0.3	0.0	1.8	12.8	0.1	0.4	3.3	28.4	0.5	10.8	3.7	1.2	151.6
PXDN	"D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN"	ENSG00000130508	Peroxidasin	Q92626	2	1631887-1744852	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins"	"Hydrogen peroxide"	"Oxidoreductase, Peroxidase"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 79.1;Endometrial stromal cells: 99.4;Endothelial cells: 95.1;Hepatic stellate cells: 71.4;Skeletal myocytes: 120.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"EFO-21: 323.8"	"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			HPA012375	Approved				"Secreted to extracellular matrix"	NA	NA		9100000	"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"			"HPA012375: AB_1855965"	"unprognostic (4.37e-2)"	"prognostic unfavorable (6.28e-4)"	"unprognostic (2.08e-1)"	"prognostic unfavorable (2.75e-4)"	"unprognostic (8.16e-3)"	"unprognostic (1.91e-1)"	"unprognostic (1.92e-2)"	"unprognostic (3.15e-3)"	"unprognostic (6.50e-3)"	"unprognostic (1.34e-2)"	"unprognostic (6.78e-2)"	"unprognostic (2.23e-1)"	"unprognostic (6.13e-3)"	"prognostic unfavorable (6.73e-4)"	"unprognostic (1.18e-1)"	"unprognostic (7.33e-3)"	"unprognostic (5.54e-3)"	59.5	5.5	4.1	24.3	3.5	0.9	33.7	1.9	4.1	18.2	27.5	36.1	7.9	32.8	4.0	4.9	18.0	22.7	22.7	3.1	7.7	9.0	12.4	27.6	5.0	4.2	6.2	32.7	3.8	3.0	11.7	33.4	4.7	17.5	8.7	5.2	13.6	11.1	7.7	6.9	16.3	61.8	2.6	10.0	13.2	6.4	5.2	2.1	8.4	11.5	2.1	33.8	13.5	3.4	39.9	13.9	72.0	0.1	198.3	180.9	54.6	231.4	182.3	99.0	107.9	0.1	0.5	0.0	323.8	230.3	4.5	8.3	0.3	142.3	125.5	0.6	2.4	0.0	139.3	0.0	196.4	0.6	0.0	200.7	41.0	112.2	83.8	299.5	247.0	35.9	0.1	0.0	142.6	23.6	6.8	8.0	58.3	0.0	52.3	13.2	250.8	0.6	115.9	0.1	0.2	131.9	0.2	73.6	0.4	142.9	27.0	0.9	242.4	162.8	79.7	6.2	180.7	0.2	205.4	1.0	0.8	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.3	0.0	0.0	4.1	3.5	1.9	4.1	3.1	7.7	4.2	6.2	4.7	2.6	5.2	3.4	79.1	6.4	2.3	2.6	0.4	2.9	2.8	12.8	0.6	2.5	17.5	14.1	5.8	17.2	7.0	1.8	0.0	0.6	0.2	0.3	0.0	10.4	33.4	4.2	99.4	95.1	1.8	0.0	6.6	0.0	11.3	45.2	0.0	3.4	1.3	43.7	71.4	1.8	1.9	0.0	7.3	1.3	20.3	5.7	4.4	40.7	26.8	0.7	7.2	8.4	0.6	10.0	1.0	55.8	0.7	0.5	0.1	15.1	0.0	14.0	0.0	0.2	6.7	0.8	46.0	120.1	51.1	22.0	16.0	0.5	2.8	1.4	1.0	33.3	0.5	1.4
PXDNL	"FLJ25471, PMR1"	ENSG00000147485	"Peroxidasin like"	A1KZ92	8	51319577-51809445	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Hydrogen peroxide"	"Endonuclease, Hydrolase, Nuclease, Oxidoreductase, Peroxidase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	5	"heart muscle: 45.3"	"Cell type enhanced"	"Detected in some"		"Cardiomyocytes: 42.2;Early spermatids: 43.8;Excitatory neurons: 25.2;Inhibitory neurons: 68.8;Microglial cells: 16.9;Muller glia cells: 18.6;Spermatocytes: 24.2"	"Group enriched"	"Detected in some"	4	"breast cancer: 1.7;glioma: 0.7;renal cancer: 0.8;testis cancer: 1.7"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	7	"AF22: 7.7;Daudi: 5.9;SH-SY5Y: 6.1"									HPA007919			Approved	Nucleoplasm,Cytosol	"Intracellular and membrane"	NA	NA				"Cluster 44: Heart - Cardiac muscle contraction"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	"Nucleoplasm, Cytosol"		"HPA007919: AB_1855966"	"prognostic unfavorable (3.27e-5)"	"unprognostic (4.59e-4)"	"unprognostic (5.57e-3)"	"unprognostic (2.83e-3)"	"unprognostic (2.71e-1)"	"unprognostic (5.14e-2)"	"unprognostic (1.18e-1)"	"unprognostic (7.18e-3)"	"unprognostic (1.85e-1)"	"unprognostic (1.15e-1)"	"unprognostic (7.07e-2)"	"unprognostic (1.07e-1)"	"unprognostic (2.60e-4)"	"unprognostic (2.28e-2)"	"unprognostic (3.35e-2)"	"unprognostic (2.42e-2)"	"unprognostic (2.97e-4)"	1.6	0.1	0.2	0.2	0.1	0.0	0.2	0.2	0.6	0.1	0.0	0.1	0.0	0.1	9.4	0.2	0.0	0.1	45.3	0.2	0.3	1.6	0.0	0.2	0.3	0.5	0.6	0.1	0.0	0.2	0.0	0.0	0.8	0.2	0.1	2.9	0.3	0.0	1.4	0.2	0.2	0.0	0.1	0.4	0.0	5.0	0.2	0.5	0.3	2.1	0.5	0.0	0.0	0.4	0.5	0.0	7.7	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.1	5.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	6.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.3	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.2	0.6	0.2	0.3	0.5	0.6	0.8	0.1	0.2	0.4	0.3	0.0	0.0	10.7	0.0	0.1	0.1	0.0	0.0	1.2	3.7	0.1	42.2	0.0	0.0	0.0	0.0	0.0	1.5	0.0	1.9	0.0	43.8	0.0	0.0	0.3	0.0	0.0	25.2	0.0	0.0	5.3	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	68.8	0.0	0.0	0.0	0.0	6.3	0.0	0.1	0.0	16.9	0.0	18.6	0.0	14.1	14.9	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.6	0.0	0.2	0.8	24.2	1.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0
PYCR1	P5C	ENSG00000183010	"Pyrroline-5-carboxylate reductase 1"	P32322	17	81932384-81942412	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Amino-acid biosynthesis, Proline biosynthesis, Stress response"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"pancreas: 111.8;salivary gland: 121.1"	"Cell type enhanced"	"Detected in many"		"Exocrine glandular cells: 63.8;Extravillous trophoblasts: 63.8;Intestinal goblet cells: 83.4;Prostatic glandular cells: 59.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"memory B-cell: 4.2"	"Group enriched"	"Detected in many"	8	"B-cells: 4.2;dendritic cells: 1.9;T-cells: 1.6"	"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA047660	Approved					NA	NA			"Cluster 43: B-cells - Humoral immune response"	"Cluster 25: Pancreas - Digestion"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 30: Mammary glandular cells - Lactation"			"HPA047660: AB_2680115"	"unprognostic (1.12e-2)"	"unprognostic (2.13e-2)"	"unprognostic (7.04e-2)"	"unprognostic (7.27e-2)"	"unprognostic (9.86e-2)"	"unprognostic (1.60e-1)"	"prognostic unfavorable (2.33e-4)"	"unprognostic (2.80e-1)"	"unprognostic (9.36e-3)"	"unprognostic (6.65e-2)"	"unprognostic (3.02e-3)"	"unprognostic (7.12e-2)"	"prognostic unfavorable (7.33e-12)"	"unprognostic (7.98e-2)"	"unprognostic (1.56e-1)"	"unprognostic (1.12e-2)"	"unprognostic (5.92e-2)"	7.5	4.1	13.8	13.8	14.1	12.5	17.4	13.2	15.2	24.2	9.6	23.8	14.3	10.6	2.5	18.7	9.7	8.9	10.0	12.5	14.4	6.3	8.7	13.6	6.9	16.1	13.9	7.5	111.8	1.9	21.6	11.7	14.8	25.5	14.4	0.9	121.1	7.8	11.5	6.3	12.5	12.2	12.7	8.0	42.4	15.1	15.8	2.6	8.5	2.0	6.7	12.0	10.3	14.2	107.4	111.9	62.7	228.3	36.7	69.0	117.2	176.0	85.4	54.7	73.7	129.3	116.9	163.2	38.0	188.9	33.3	45.8	148.2	67.1	32.7	42.4	18.6	96.5	56.5	350.8	213.8	64.8	70.6	58.5	129.8	68.2	178.7	64.8	95.5	129.4	314.0	147.2	35.1	376.4	68.1	49.5	52.8	291.9	170.1	0.9	105.6	205.5	49.9	38.7	237.7	167.2	36.9	203.6	219.5	46.3	210.0	117.1	70.1	53.7	201.8	91.4	66.3	183.4	141.3	156.2	57.2	0.8	178.1	0.0	0.1	0.0	0.2	0.2	0.4	4.2	0.7	0.2	1.3	1.8	1.6	1.2	0.0	0.3	0.0	1.9	0.3	1.1	13.8	14.1	13.2	15.2	12.5	14.4	16.1	13.9	14.8	12.7	15.8	14.2	2.3	0.0	3.9	2.3	9.1	7.0	11.4	12.2	4.6	0.3	50.6	29.5	0.6	1.5	7.2	3.7	0.0	2.0	2.3	17.2	0.0	13.3	13.8	3.4	14.6	4.7	10.8	27.8	0.9	63.8	63.8	24.9	35.7	13.8	4.5	13.9	2.5	1.8	5.0	3.3	1.4	83.4	8.2	0.0	5.4	32.4	7.5	0.8	8.8	0.0	0.7	0.5	0.0	3.5	0.7	48.0	19.5	3.8	34.1	59.6	1.2	1.9	1.3	0.2	0.0	3.3	17.8	28.2	16.9	8.0	6.0	3.8	1.9	15.5	43.1	8.6
PYCR2	P5CR2	ENSG00000143811	"Pyrroline-5-carboxylate reductase 2"	Q96C36	1	225919877-225924340	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Amino-acid biosynthesis, Proline biosynthesis"	Oxidoreductase	"Disease variant, Leukodystrophy"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"											HPA056873	Approved		Approved	Mitochondria		NA	NA			"Cluster 48: NK-cells - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 51: Myeloid cells - Hemostasis"	Mitochondria		"HPA056873: AB_2683263"	"unprognostic (1.11e-1)"	"unprognostic (8.08e-2)"	"prognostic unfavorable (5.02e-5)"	"unprognostic (2.91e-2)"	"unprognostic (1.76e-1)"	"unprognostic (1.03e-1)"	"unprognostic (4.20e-3)"	"unprognostic (1.56e-2)"	"unprognostic (6.89e-2)"	"unprognostic (1.12e-1)"	"unprognostic (9.07e-3)"	"unprognostic (1.56e-1)"	"prognostic unfavorable (1.42e-6)"	"unprognostic (9.69e-2)"	"unprognostic (2.61e-1)"	"unprognostic (6.44e-2)"	"unprognostic (1.16e-3)"	38.0	71.7	53.2	35.8	62.4	47.3	35.8	68.1	54.2	46.4	51.8	39.6	22.3	48.5	26.4	32.3	44.7	22.4	62.3	50.4	61.3	40.2	40.3	38.2	47.2	69.0	61.2	47.9	47.2	42.0	57.0	28.5	66.0	39.6	18.3	34.0	39.6	40.9	66.8	28.3	34.4	25.7	68.6	49.5	38.9	34.4	59.2	43.9	30.0	49.1	33.9	50.3	33.3	72.5	72.6	59.6	35.0	59.1	38.8	40.0	73.2	74.8	46.3	49.7	44.1	77.2	58.3	126.1	156.6	55.0	39.1	81.6	50.5	58.6	28.3	154.6	107.5	120.6	60.2	81.5	59.8	107.9	189.1	38.8	72.3	56.1	64.1	44.1	47.8	103.7	178.4	81.6	50.9	60.5	135.8	120.9	196.0	112.8	80.4	120.2	79.0	263.6	65.2	58.3	44.0	56.7	62.4	48.7	161.0	27.9	62.3	202.0	40.3	38.4	46.5	82.9	104.4	129.9	156.2	127.4	60.7	80.6	109.3	38.4	19.6	39.6	45.5	29.2	47.8	34.4	43.8	42.4	31.3	41.9	74.9	62.4	13.3	67.9	26.3	59.2	44.0	45.1	53.2	62.4	68.1	54.2	50.4	61.3	69.0	61.2	66.0	68.6	59.2	72.5	28.0	19.2	22.8	11.4	31.6	14.8	64.6	53.4	8.0	15.6	24.3	21.2	47.6	20.0	24.8	35.0	14.6	90.6	39.1	12.9	49.0	50.0	8.2	92.8	25.6	26.7	26.5	58.7	4.6	34.0	46.3	23.7	10.2	31.8	38.7	74.9	21.0	16.6	40.0	13.5	5.8	17.8	57.0	20.4	19.8	8.8	38.2	31.5	33.8	8.4	46.4	46.9	46.4	5.5	29.3	29.1	15.8	37.6	23.1	42.1	18.3	35.8	55.4	42.7	26.3	19.8	24.4	40.1	46.2	9.4	12.8	41.7	34.9	44.9	16.1	40.4
PYCR3	"FLJ13852, PYCRL"	ENSG00000104524	"Pyrroline-5-carboxylate reductase 3"	Q53H96	8	143603210-143609773	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Amino-acid biosynthesis, Proline biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Collecting duct cells: 14.7;Ductal cells: 10.2;Exocrine glandular cells: 9.1;Extravillous trophoblasts: 11.8;Proximal tubular cells: 12.4;Theca cells: 14.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"naive B-cell: 4.7"	"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA053776, HPA063416, HPA069706"	Uncertain		Supported	"Cytokinetic bridge,Mitotic spindle,Cytosol"		Yes	NA			"Cluster 24: B-cells - Unknown function"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 7: Non-specific - Mitochondria"	Cytosol	"Cytokinetic bridge, Mitotic spindle"	"HPA053776: , HPA063416: AB_2685010, HPA069706: AB_2686178"	"unprognostic (2.12e-2)"	"unprognostic (3.16e-2)"	"unprognostic (2.74e-1)"	"unprognostic (2.44e-1)"	"unprognostic (1.06e-2)"	"unprognostic (2.30e-1)"	"unprognostic (7.68e-3)"	"unprognostic (1.79e-1)"	"unprognostic (1.96e-1)"	"unprognostic (2.26e-2)"	"unprognostic (5.85e-2)"	"unprognostic (5.44e-2)"	"unprognostic (1.82e-2)"	"unprognostic (3.64e-2)"	"unprognostic (2.96e-1)"	"unprognostic (3.54e-2)"	"unprognostic (2.54e-1)"	5.0	9.7	2.8	0.4	2.9	0.6	5.2	2.7	3.3	5.1	1.0	4.2	0.5	5.2	1.1	7.1	6.0	0.8	3.9	2.9	1.6	9.7	17.2	3.8	0.9	2.3	2.2	5.1	9.2	0.6	10.0	0.4	2.7	8.7	0.6	0.7	5.8	0.5	3.0	4.0	4.1	0.4	1.5	5.9	5.5	7.0	2.7	0.4	8.4	0.3	0.7	4.4	3.8	2.1	3.2	4.0	1.6	2.5	1.8	0.6	2.0	3.0	1.4	2.9	1.9	2.9	2.6	6.2	2.1	2.0	1.1	2.6	2.0	4.0	1.1	3.0	5.3	3.7	2.2	2.0	0.6	1.9	1.0	0.8	1.9	3.1	1.9	1.2	0.7	3.7	4.3	3.1	1.9	7.2	3.0	1.7	2.1	4.5	10.4	2.8	1.8	4.3	3.4	2.2	5.3	1.4	3.6	4.9	1.6	0.8	6.4	2.0	0.9	2.9	4.0	3.4	3.1	2.5	0.8	4.2	2.6	2.0	1.9	0.2	0.9	0.0	1.1	0.6	1.2	1.3	0.8	0.8	0.6	4.7	1.1	1.0	0.1	1.3	0.7	3.0	0.9	0.6	2.8	2.9	2.7	3.3	2.9	1.6	2.3	2.2	2.7	1.5	2.7	2.1	2.9	3.2	3.6	0.0	1.8	0.0	0.0	0.0	0.0	0.0	8.8	7.7	0.0	0.0	0.6	14.7	0.0	5.1	1.6	0.0	3.9	10.2	0.0	6.8	6.6	1.9	0.0	0.0	0.0	9.1	11.8	2.9	0.0	5.2	0.0	5.5	0.0	0.0	5.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	1.6	0.0	0.0	0.0	0.0	7.4	0.0	0.0	0.8	0.0	0.0	12.4	4.4	0.0	0.0	0.0	3.1	0.0	0.0	0.0	0.0	2.5	1.2	14.7	0.0	0.0
QDPR	"DHPR, PKU2, SDR33C1"	ENSG00000151552	"Quinoid dihydropteridine reductase"	P09417	4	17460261-17512206	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Tetrahydrobiopterin biosynthesis"	Oxidoreductase	"Disease variant, Phenylketonuria"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 752.2;choroid plexus: 301.8"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 337.6;Muller glia cells: 387.2;Oligodendrocytes: 481.3;Proximal tubular cells: 527.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA058951, HPA065649"	Enhanced		Approved	Mitochondria		NA	NA		2500000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 70: Brain - Nervous system development"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Mitochondria		"HPA058951: AB_2683861, HPA065649: AB_2685526"	"unprognostic (1.30e-2)"	"unprognostic (4.29e-1)"	"unprognostic (8.27e-2)"	"unprognostic (2.52e-1)"	"unprognostic (1.21e-1)"	"unprognostic (1.20e-1)"	"unprognostic (3.29e-3)"	"unprognostic (3.80e-3)"	"unprognostic (1.19e-1)"	"unprognostic (1.45e-1)"	"unprognostic (6.82e-3)"	"unprognostic (2.07e-1)"	"prognostic favorable (7.84e-6)"	"unprognostic (1.58e-1)"	"unprognostic (2.60e-1)"	"unprognostic (9.01e-2)"	"unprognostic (3.19e-1)"	66.6	74.3	515.1	10.2	720.1	15.1	26.4	696.9	571.9	15.8	301.8	21.2	25.6	16.5	40.1	15.6	17.3	17.7	43.4	457.6	578.5	110.1	197.2	23.3	11.9	663.0	752.2	18.3	28.8	49.9	32.7	11.8	688.6	28.7	17.0	40.1	36.3	19.5	108.6	16.2	23.9	17.9	524.9	14.3	23.7	12.4	602.6	13.6	22.1	61.2	13.3	14.5	15.1	663.7	33.1	62.5	30.2	35.8	66.1	32.3	41.5	43.2	22.3	47.5	41.6	52.2	46.4	12.2	28.0	30.3	50.8	18.4	40.3	58.4	33.7	35.3	7.3	34.8	33.4	128.3	37.3	46.2	2.9	40.8	35.6	31.6	40.3	25.9	24.5	33.2	37.0	29.0	50.6	19.2	65.0	77.8	44.8	36.7	45.4	27.0	21.0	52.2	48.2	17.5	47.1	64.3	31.9	6.7	156.6	35.0	15.7	19.0	37.7	23.6	41.1	26.5	38.2	43.1	67.7	85.3	52.0	43.1	41.7	0.3	38.9	3.0	31.3	61.3	29.8	18.6	33.1	32.3	48.3	18.3	37.4	32.6	1.1	29.8	48.4	115.1	20.3	34.4	515.1	720.1	696.9	571.9	457.6	578.5	663.0	752.2	688.6	524.9	602.6	663.7	20.3	28.9	31.5	10.7	14.8	20.0	21.3	32.2	18.8	36.2	37.6	28.3	74.4	50.1	19.5	38.6	8.4	69.6	22.8	13.7	109.5	41.1	1.0	11.8	19.1	17.2	174.3	30.1	23.1	23.4	34.2	27.1	27.5	17.8	25.4	42.3	20.7	337.6	80.3	82.4	21.9	31.1	34.6	38.1	23.9	4.8	22.7	32.2	152.9	12.2	23.4	387.2	16.5	15.1	481.3	16.9	11.6	38.0	23.6	23.2	41.4	527.2	6.2	31.4	26.3	27.5	25.4	3.3	58.9	29.7	16.1	18.3	18.5	90.0	35.7	17.3
QSOX1	QSCN6	ENSG00000116260	"Quiescin sulfhydryl oxidase 1"	O00391	1	180154869-180204030	"Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enriched"	"Detected in many"	6	"Extravillous trophoblasts: 1616.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HHSteC: 1918.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA056243			Supported	"Golgi apparatus,Vesicles"	"Secreted to extracellular matrix"	NA	NA		2600000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 38: Extravillous trophoblasts - Unknown function"	"Golgi apparatus"	Vesicles	"HPA056243: AB_2683077"	"unprognostic (1.13e-1)"	"unprognostic (2.62e-3)"	"unprognostic (2.46e-1)"	"unprognostic (2.49e-2)"	"unprognostic (2.00e-2)"	"unprognostic (2.73e-1)"	"unprognostic (5.47e-2)"	"unprognostic (2.22e-1)"	"unprognostic (3.94e-1)"	"unprognostic (3.12e-2)"	"unprognostic (5.07e-2)"	"unprognostic (2.80e-3)"	"prognostic unfavorable (1.86e-5)"	"unprognostic (3.25e-1)"	"unprognostic (2.14e-1)"	"unprognostic (3.53e-2)"	"unprognostic (1.40e-1)"	84.8	84.9	35.8	52.1	39.4	115.5	53.2	42.7	47.3	81.7	41.1	100.1	67.5	75.2	70.2	178.4	82.3	150.3	244.9	41.5	43.4	73.8	81.7	200.0	16.3	50.0	40.7	196.1	136.3	21.0	60.2	158.9	43.2	92.3	80.9	15.2	105.6	57.5	91.2	58.6	85.7	60.0	44.0	61.9	178.3	172.9	42.6	12.1	31.9	46.0	19.6	174.1	108.7	57.7	441.4	62.0	14.8	181.0	179.1	367.8	712.5	456.5	456.6	381.6	267.1	7.3	137.7	6.8	276.7	367.8	52.6	93.7	17.6	123.5	185.0	26.4	28.0	14.1	33.6	19.4	1918.6	48.6	129.2	197.9	55.5	408.0	484.3	499.9	569.4	32.1	20.2	66.3	255.3	76.4	10.4	89.7	49.4	302.6	174.6	19.7	33.0	11.8	63.1	123.6	51.9	52.6	133.8	179.8	91.9	32.2	33.0	226.3	678.3	473.8	187.5	322.0	392.9	48.3	84.4	12.2	180.9	153.9	146.0	16.2	53.1	20.6	14.0	29.9	10.2	5.4	9.1	9.6	39.2	3.2	8.1	8.0	40.2	16.9	28.6	8.0	11.5	28.6	35.8	39.4	42.7	47.3	41.5	43.4	50.0	40.7	43.2	44.0	42.6	57.7	36.6	57.7	101.6	8.5	7.7	13.8	27.4	81.2	7.4	11.5	86.2	47.9	48.3	51.5	112.5	71.7	25.0	19.5	10.7	138.1	0.0	230.4	49.2	49.2	19.4	41.7	46.2	6.9	17.2	130.1	1616.7	78.0	136.6	80.4	25.4	27.1	89.3	4.3	68.6	6.7	17.0	185.7	132.2	45.2	35.3	20.1	177.7	48.9	44.4	8.4	49.7	53.5	10.3	24.6	23.9	249.8	165.6	71.1	12.8	35.7	9.0	9.1	47.8	6.7	32.9	13.6	31.3	30.2	32.7	10.2	9.9	154.3	13.9	13.9	89.9	68.0
QSOX2	"DKFZp762A2013, QSCN6L1, SOXN"	ENSG00000165661	"Quiescin sulfhydryl oxidase 2"	Q6ZRP7	9	136206333-136245812	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"naive B-cell: 1.0"	"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA012716, HPA017280"	Uncertain		Enhanced	"Nucleoplasm,Golgi apparatus"	"Intracellular and membrane"	NA	NA		9600000	"Cluster 19: B-cells - Humoral immune response"	"Cluster 26: Pituitary gland - Hormone signaling"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis"	"Golgi apparatus"	Nucleoplasm	"HPA012716: AB_2173315, HPA017280: AB_2669565"	"unprognostic (7.29e-2)"	"unprognostic (7.35e-3)"	"unprognostic (6.23e-2)"	"unprognostic (5.28e-2)"	"unprognostic (1.49e-1)"	"unprognostic (4.46e-3)"	"unprognostic (1.10e-3)"	"unprognostic (4.48e-2)"	"unprognostic (1.20e-1)"	"unprognostic (4.06e-3)"	"unprognostic (5.96e-2)"	"unprognostic (2.56e-2)"	"prognostic unfavorable (9.64e-6)"	"unprognostic (1.23e-2)"	"unprognostic (1.22e-1)"	"unprognostic (1.75e-2)"	"unprognostic (1.10e-2)"	7.5	7.6	7.3	11.2	7.6	15.9	5.9	12.9	8.1	7.3	5.9	6.7	5.1	8.3	10.6	5.3	8.6	4.6	7.6	7.3	7.6	7.5	8.6	7.0	17.5	7.3	7.6	9.5	18.8	8.1	32.3	4.9	6.9	6.4	5.4	12.3	5.9	3.7	5.6	11.1	11.8	6.7	6.0	15.7	7.1	10.8	8.0	8.1	11.7	3.4	14.6	6.3	5.8	7.3	14.7	35.0	28.6	38.2	15.8	19.0	35.9	18.3	20.4	34.9	31.9	26.4	31.1	22.6	29.5	24.7	64.1	46.7	34.2	26.5	28.0	33.5	17.2	12.1	59.8	29.3	22.5	36.4	17.8	15.3	26.3	34.8	41.8	15.4	25.9	23.3	29.8	59.1	18.8	25.0	13.6	24.2	34.0	44.2	22.3	24.8	37.1	37.2	12.0	13.1	30.5	23.1	28.9	22.6	15.9	18.5	16.3	21.1	15.0	42.2	30.4	35.1	42.6	20.9	29.9	49.7	28.3	18.9	40.5	0.4	0.0	0.1	0.1	0.0	0.1	0.4	0.1	0.0	0.0	1.0	0.0	0.1	0.0	0.1	0.0	0.2	0.0	0.0	7.3	7.6	12.9	8.1	7.3	7.6	7.3	7.6	6.9	6.0	8.0	7.3	8.8	9.6	7.9	13.7	17.7	5.7	2.8	2.2	1.8	24.4	2.3	2.9	4.3	0.0	4.4	5.5	18.8	1.3	5.8	1.6	1.9	3.4	6.7	5.7	7.4	6.6	16.3	14.5	10.1	4.0	2.8	5.2	4.1	5.6	1.3	7.1	2.9	4.4	2.3	5.0	11.1	3.8	0.0	3.7	8.2	7.3	5.9	3.3	0.0	8.4	4.3	2.6	4.1	6.0	10.7	3.4	0.7	7.2	5.4	7.9	0.9	2.3	9.0	8.8	6.6	9.2	4.7	19.4	24.2	1.8	11.5	1.0	5.1	7.3	3.9	3.6
RDH10	SDR16C4	ENSG00000121039	"Retinol dehydrogenase 10"	Q8IZV5	8	73294602-73325281	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Club cells: 131.7;Collecting duct cells: 204.1;Muller glia cells: 342.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"basophil: 1.2"	"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in all"		"ASC diff: 143.6;BJ: 107.4;CACO-2: 97.0;HDLM-2: 110.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA049199			Supported	"Lipid droplets"		NA	NA			"Cluster 18: Basophils - Vesicular transport"	"Cluster 77: Retina - Visual perception"	"Cluster 21: OE19 - Mitochondria"	"Cluster 5: Muller glia cells - Visual perception"	"Lipid droplets"		"HPA049199: AB_2680673"	"unprognostic (1.78e-1)"	"unprognostic (1.23e-1)"	"unprognostic (8.86e-2)"	"unprognostic (2.52e-1)"	"unprognostic (2.45e-2)"	"unprognostic (1.13e-2)"	"unprognostic (1.14e-1)"	"unprognostic (2.80e-2)"	"unprognostic (7.87e-2)"	"unprognostic (7.98e-2)"	"unprognostic (1.18e-3)"	"unprognostic (8.88e-3)"	"unprognostic (1.13e-2)"	"unprognostic (4.38e-2)"	"unprognostic (1.67e-1)"	"unprognostic (2.98e-3)"	"unprognostic (6.23e-2)"	43.3	6.2	4.2	23.4	5.3	3.3	10.5	4.1	4.1	18.2	16.0	16.6	32.4	14.1	3.9	19.8	7.8	30.2	11.6	4.9	5.9	43.8	41.0	13.6	11.0	11.5	6.8	5.0	34.5	8.4	26.8	36.3	6.4	21.5	15.2	86.3	39.2	13.1	6.9	8.3	30.7	14.9	5.8	7.2	24.8	16.6	20.4	6.1	6.5	8.2	8.8	69.2	11.3	6.7	13.8	39.2	4.3	17.9	143.6	10.5	39.0	107.4	17.4	4.1	6.8	97.0	38.6	9.6	13.9	60.4	6.3	35.6	19.6	15.5	8.4	110.7	49.0	17.0	37.6	30.1	5.6	8.2	18.0	6.3	19.6	16.5	15.3	18.3	15.6	9.4	20.0	13.7	7.0	6.1	8.5	3.4	5.2	84.0	19.0	7.4	4.4	5.8	28.2	19.4	2.6	3.4	9.1	66.3	5.5	5.4	13.1	4.2	24.0	6.3	10.6	28.9	8.3	8.8	10.0	7.8	5.0	7.3	14.7	1.2	0.1	0.2	0.3	0.1	0.2	0.1	0.3	0.4	0.2	0.0	0.6	0.3	0.1	0.0	0.1	0.0	0.2	0.1	4.2	5.3	4.1	4.1	4.9	5.9	11.5	6.8	6.4	5.8	20.4	6.7	14.5	12.8	29.8	3.6	2.5	13.5	9.7	75.6	16.5	3.2	29.1	25.5	9.1	25.8	131.7	204.1	22.9	19.1	11.2	25.5	3.9	16.3	80.6	38.3	50.0	9.7	4.2	1.3	1.4	17.6	23.8	44.6	49.5	71.5	2.5	1.2	3.3	49.2	20.9	3.3	1.0	16.8	40.7	5.4	7.8	9.9	2.8	10.0	17.8	6.5	1.9	342.1	3.1	4.5	2.0	56.9	31.5	3.8	6.4	41.2	47.7	22.6	44.2	16.2	0.0	11.4	20.5	11.0	8.0	24.7	13.9	42.0	7.1	1.6	24.2	17.7
RDH11	"ARSDR1, MDT1, SDR7C1"	ENSG00000072042	"Retinol dehydrogenase 11"	Q8TC12	14	67676800-67695793	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Cataract, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"prostate: 582.0"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 241.8;Muller glia cells: 299.7;Prostatic glandular cells: 285.7"	"Cancer enriched"	"Detected in all"	13	"prostate cancer: 286.6"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB046011	Enhanced				"Intracellular and membrane"	NA	NA		340000	"Cluster 46: Basophils - DNA binding"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 5: Muller glia cells - Visual perception"			"CAB046011: AB_11129613"	"unprognostic (1.38e-1)"	"unprognostic (6.86e-3)"	"unprognostic (1.77e-1)"	"prognostic favorable (2.62e-4)"	"unprognostic (6.06e-2)"	"prognostic unfavorable (2.89e-5)"	"unprognostic (9.29e-2)"	"unprognostic (1.98e-1)"	"unprognostic (1.05e-1)"	"unprognostic (3.58e-2)"	"unprognostic (2.91e-2)"	"unprognostic (1.27e-1)"	"prognostic favorable (1.30e-7)"	"unprognostic (1.65e-1)"	"unprognostic (1.68e-1)"	"unprognostic (2.18e-1)"	"unprognostic (4.74e-2)"	23.6	59.5	39.3	24.5	43.2	13.9	28.7	50.2	54.4	32.6	35.9	29.2	34.1	33.2	86.0	34.6	23.5	42.7	17.6	40.4	47.2	106.0	153.1	34.9	20.4	49.2	47.7	28.9	42.6	79.8	23.4	21.9	49.3	582.0	31.4	73.9	44.2	34.4	8.3	31.4	23.9	43.6	49.8	22.2	31.9	28.4	46.1	30.7	61.7	13.5	26.2	34.3	30.3	58.4	183.7	81.9	71.3	82.0	111.5	100.4	59.3	68.0	134.2	83.7	150.9	68.6	216.7	31.7	51.2	64.6	104.8	142.5	104.0	150.8	113.7	63.0	42.6	65.1	40.7	69.0	106.9	24.3	46.0	94.4	98.0	109.3	92.0	63.9	97.4	87.0	52.1	101.1	77.2	97.5	72.2	38.8	40.4	49.7	92.8	53.6	87.4	45.8	194.1	93.0	73.8	62.0	71.2	89.7	99.1	58.2	100.7	38.3	74.2	89.5	101.1	38.9	49.5	47.5	40.0	40.7	115.8	66.0	74.3	282.4	71.1	104.0	62.3	57.7	68.2	39.0	67.7	61.5	51.3	45.5	67.3	64.8	11.0	56.3	65.4	59.1	65.1	115.8	39.3	43.2	50.2	54.4	40.4	47.2	49.2	47.7	49.3	49.8	46.1	58.4	27.0	25.6	66.0	38.2	29.2	11.5	40.0	77.9	16.5	53.5	45.4	24.5	20.4	68.6	59.9	47.8	50.1	24.9	32.4	26.8	7.9	92.5	2.5	21.9	50.9	39.3	43.3	29.2	33.3	84.0	38.1	37.5	19.9	38.2	29.2	46.3	47.8	241.8	35.8	79.1	37.6	28.9	89.5	42.4	15.4	6.1	43.2	35.9	35.6	17.8	39.8	299.7	37.0	70.4	43.4	61.2	36.7	56.1	27.3	285.7	17.5	56.0	23.9	97.0	46.0	29.7	38.7	25.8	24.0	20.2	19.2	63.5	29.8	66.7	25.3	46.1
RDH12	"FLJ30273, LCA13, RP53, SDR7C2"	ENSG00000139988	"Retinol dehydrogenase 12"	Q96NR8	14	67701886-67734451	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Sensory transduction, Vision"	Oxidoreductase	"Disease variant, Leber congenital amaurosis, Retinitis pigmentosa"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"retina: 222.7;skin 1: 63.8"	"Group enriched"	"Detected in some"	5	"Cone photoreceptor cells: 146.0;Rod photoreceptor cells: 453.2"	"Cancer enhanced"	"Detected in many"		"head and neck cancer: 5.6"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"								"Intracellular and membrane"	NA	NA				"Cluster 79: Retina - Phototransduction"		"Cluster 46: Photoreceptor cells - Phototransduction"				"unprognostic (4.25e-3)"	"unprognostic (4.50e-3)"	"unprognostic (1.16e-1)"	"unprognostic (7.53e-2)"	"unprognostic (2.99e-1)"	"unprognostic (1.99e-1)"	"unprognostic (6.70e-2)"	"unprognostic (2.13e-1)"	"unprognostic (1.69e-2)"	"unprognostic (2.72e-3)"	"unprognostic (7.59e-2)"	"unprognostic (2.02e-1)"	"unprognostic (1.42e-2)"	"unprognostic (6.47e-2)"	"unprognostic (7.83e-2)"	"unprognostic (3.58e-1)"	"unprognostic (3.92e-1)"	0.1	4.1	1.3	0.1	1.0	0.1	2.2	1.0	1.4	11.0	0.4	0.0	0.3	0.0	8.7	22.1	0.5	17.6	0.0	0.9	1.2	13.6	3.8	0.1	0.0	1.2	2.3	0.0	3.2	0.0	0.9	0.1	1.2	0.5	0.0	222.7	1.7	0.1	0.1	63.8	0.1	0.0	0.6	0.0	12.4	0.1	4.6	0.4	1.2	0.0	1.6	0.0	23.6	1.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.3	0.0	0.5	0.1	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.1	0.0	0.4	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.2	0.4	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.3	1.0	1.0	1.4	0.9	1.2	1.2	2.3	1.2	0.6	4.6	1.1	0.0	0.0	0.0	0.7	0.0	4.7	0.3	0.0	0.6	39.8	0.1	0.1	0.0	20.0	0.3	1.8	146.0	0.0	0.0	0.1	0.0	0.7	0.2	1.8	1.1	2.2	0.0	0.0	1.2	1.7	0.0	0.4	14.3	1.7	0.0	0.0	0.0	5.7	0.2	20.2	0.9	0.0	0.0	0.6	0.9	0.0	0.3	0.2	1.8	1.0	0.0	53.0	0.0	1.5	0.2	1.5	2.6	0.0	0.0	0.3	0.1	12.5	0.2	453.2	0.0	0.0	0.2	0.0	0.1	4.7	38.6	0.0	0.1	0.1	0.1	0.3
RDH13	SDR7C3	ENSG00000160439	"Retinol dehydrogenase 13"	Q8NBN7	19	55039108-55071291	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"Syncytiotrophoblasts: 209.7;Urothelial cells: 110.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"HEK 293: 60.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA042006	Approved		Supported	Mitochondria,Cytosol	"Intracellular and membrane"	NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"	"Mitochondria, Cytosol"		"HPA042006: AB_10960270"	"unprognostic (9.26e-2)"	"unprognostic (1.14e-2)"	"unprognostic (1.08e-1)"	"unprognostic (2.15e-2)"	"unprognostic (8.74e-2)"	"unprognostic (1.08e-2)"	"unprognostic (2.48e-1)"	"unprognostic (3.60e-2)"	"unprognostic (1.82e-1)"	"unprognostic (9.42e-3)"	"unprognostic (1.61e-1)"	"unprognostic (2.45e-3)"	"prognostic favorable (2.09e-4)"	"unprognostic (2.19e-2)"	"unprognostic (2.23e-1)"	"unprognostic (2.12e-2)"	"unprognostic (1.66e-3)"	4.5	4.8	2.5	3.4	2.6	2.2	4.5	3.9	3.6	9.4	3.9	8.6	6.7	4.2	0.7	19.8	4.8	3.0	13.0	2.4	3.5	9.2	8.2	4.4	3.5	3.5	4.2	3.7	8.6	12.4	6.4	10.1	3.7	6.3	3.8	2.1	9.6	3.7	9.7	21.0	6.1	2.0	1.6	6.2	10.5	5.3	3.8	2.2	7.5	4.8	2.7	5.1	12.2	2.3	10.9	12.3	2.9	10.3	1.5	3.0	17.9	3.4	2.1	3.7	6.4	23.3	15.7	9.4	5.3	1.2	2.7	14.1	7.8	7.2	1.7	7.3	60.0	12.2	9.8	14.6	2.9	12.4	8.0	2.6	6.3	3.0	2.9	3.7	3.0	5.2	27.2	2.9	2.3	13.4	6.1	9.6	2.5	17.7	25.7	15.7	6.7	27.6	8.2	37.3	8.8	6.2	8.9	31.3	7.0	2.7	12.0	9.3	3.0	0.3	3.7	0.1	8.2	7.8	11.0	9.6	9.1	10.6	6.6	3.8	4.1	4.1	8.2	6.3	7.7	5.4	6.3	7.6	4.2	5.8	8.4	6.1	1.9	7.8	5.0	6.4	5.5	3.0	2.5	2.6	3.9	3.6	2.4	3.5	3.5	4.2	3.7	1.6	3.8	2.3	8.9	16.0	13.1	3.9	6.6	10.7	31.7	11.1	7.4	21.0	12.2	9.9	27.5	20.0	19.3	14.7	41.7	41.3	9.4	47.2	11.7	13.5	24.3	18.3	8.8	9.1	12.0	4.2	9.4	6.5	29.0	7.1	46.4	31.8	8.2	24.4	18.5	7.3	11.5	25.2	10.0	27.5	12.2	4.9	5.0	13.2	3.7	4.2	7.2	4.7	5.0	9.0	6.2	5.0	2.9	14.5	35.7	3.4	8.7	30.6	20.3	4.8	12.8	25.3	6.6	5.1	6.5	3.2	8.9	11.1	17.5	209.7	9.2	11.1	28.1	110.1
RDH14	"PAN2, SDR7C4"	ENSG00000240857	"Retinol dehydrogenase 14"	Q9HBH5	2	18554723-18560679	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA056686, HPA078577"	Approved		Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 26: Non-specific - Mitochondria"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 66: Spermatocytes - Spermatogenesis"	Nucleoplasm	Cytosol	"HPA056686: AB_2683209, HPA078577: "	"unprognostic (5.79e-2)"	"unprognostic (3.96e-2)"	"unprognostic (1.64e-1)"	"unprognostic (7.03e-2)"	"unprognostic (1.99e-2)"	"unprognostic (8.71e-3)"	"unprognostic (1.11e-2)"	"unprognostic (1.48e-1)"	"unprognostic (2.12e-1)"	"unprognostic (8.83e-3)"	"unprognostic (6.41e-2)"	"unprognostic (1.92e-1)"	"unprognostic (1.82e-1)"	"unprognostic (8.98e-2)"	"unprognostic (1.58e-2)"	"unprognostic (4.32e-2)"	"unprognostic (3.69e-2)"	14.4	14.5	10.6	8.3	10.8	5.4	12.6	11.0	12.4	10.1	15.7	14.6	11.6	14.2	12.2	9.8	11.9	9.4	29.8	10.5	10.8	14.0	18.5	11.8	12.5	10.8	10.5	10.0	14.1	18.7	11.3	13.0	11.3	13.3	10.4	8.3	10.7	11.0	28.1	9.6	11.4	12.0	11.1	11.5	14.6	11.5	10.7	12.5	11.1	27.1	9.5	15.5	10.2	11.7	28.6	8.9	7.3	6.0	21.8	22.9	24.7	16.8	17.7	15.2	15.0	6.9	14.6	28.2	9.7	10.3	19.7	15.3	10.8	19.9	17.6	15.6	28.8	10.8	10.6	21.4	18.6	13.7	14.1	17.5	19.9	14.8	22.9	21.2	14.2	11.2	19.9	9.2	25.2	9.2	11.8	23.7	19.9	21.9	24.1	16.5	20.1	12.1	29.9	18.4	11.2	19.3	9.3	20.4	25.8	15.4	10.1	7.2	14.4	21.5	13.1	16.6	20.6	26.0	23.1	20.8	15.1	9.0	17.1	1.4	1.4	6.5	3.3	1.7	5.5	7.3	3.9	4.9	1.9	11.6	5.5	4.5	0.5	3.1	1.7	6.1	5.1	1.3	10.6	10.8	11.0	12.4	10.5	10.8	10.8	10.5	11.3	11.1	10.7	11.7	21.7	16.0	12.8	0.0	36.1	24.5	31.0	27.9	31.3	23.5	20.1	24.5	55.6	32.9	20.9	16.5	6.2	44.6	34.8	20.6	31.3	37.8	27.4	27.4	19.7	19.4	13.2	18.7	0.0	35.3	50.3	38.5	20.4	19.7	12.7	16.4	20.3	30.0	24.2	15.2	0.0	27.1	20.3	17.2	14.6	13.6	66.8	15.4	23.2	0.0	23.2	31.3	29.9	0.0	0.0	27.0	36.3	44.8	15.6	45.1	23.3	38.1	18.8	22.4	32.9	28.5	29.6	79.5	30.6	18.9	18.6	45.7	27.1	30.9	29.2	27.3
RDH16	"RODH-4, SDR9C8"	ENSG00000139547	"Retinol dehydrogenase 16"	O75452	12	56951431-56959374	"Enzymes, Metabolic proteins, Predicted membrane proteins"	"Lipid metabolism, Steroid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	152	"liver: 793.0"	"Cell type enriched"	"Detected in some"	27	"Hepatocytes: 365.1"	"Cancer enriched"	"Detected in many"	20	"liver cancer: 44.0"	"Low region specificity"	"Detected in single"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HaCaT: 2.0;hTCEpi: 4.3;OE19: 1.0"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA038518	Enhanced					NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 62: Liver - Hemostasis"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 2: Hepatocytes - Metabolism"			"HPA038518: AB_10672713"	"unprognostic (5.42e-3)"	"unprognostic (4.20e-2)"	"unprognostic (2.99e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.88e-1)"	"unprognostic (2.92e-2)"	"prognostic favorable (2.16e-5)"	"unprognostic (8.83e-3)"	"unprognostic (1.04e-1)"	"unprognostic (2.84e-1)"	"unprognostic (6.85e-2)"	"unprognostic (6.10e-1)"	"unprognostic (7.99e-12)"	"unprognostic (2.24e-1)"	"unprognostic (1.29e-2)"	"unprognostic (1.62e-1)"	"unprognostic (2.01e-2)"	0.3	0.3	0.9	0.0	0.9	0.0	0.3	0.9	1.1	1.2	0.9	0.3	0.0	0.4	0.1	1.4	0.5	0.0	0.4	0.9	0.8	0.5	793.0	0.4	0.1	0.8	0.8	0.5	0.6	0.0	0.3	0.0	0.9	5.2	0.0	0.4	0.5	2.4	0.2	2.9	0.5	0.0	0.8	2.5	0.3	1.3	0.8	0.2	0.3	0.0	1.3	0.3	1.6	0.9	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.4	0.0	0.0	4.3	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.1	0.0	1.0	0.0	0.0	0.2	0.3	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.1	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.9	0.9	1.1	0.9	0.8	0.8	0.8	0.9	0.8	0.8	0.9	0.1	0.0	0.0	2.0	1.9	0.0	1.2	0.3	0.0	2.2	0.2	0.0	2.0	5.7	0.2	0.0	0.0	0.1	0.2	0.0	0.0	0.1	8.5	0.1	0.1	0.6	0.0	13.5	0.2	0.4	0.0	0.3	0.0	0.1	0.0	0.3	3.6	365.1	0.2	1.7	0.2	0.0	0.0	6.3	0.3	5.8	0.0	0.2	0.0	0.0	0.1	0.3	0.0	0.0	1.8	0.2	0.0	0.0	0.3	5.7	0.0	0.1	0.2	1.0	0.0	0.0	0.1	1.4	0.9	0.8	0.3	0.0	0.6	0.1	0.0	0.3
RDH5	"HSD17B9, RDH1, SDR9C5"	ENSG00000135437	"Retinol dehydrogenase 5"	Q92781	12	55720367-55724705	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Lipid metabolism, Sensory transduction, Steroid metabolism, Vision"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 94.5;liver: 58.9"	"Cell type enhanced"	"Detected in many"		"Cone photoreceptor cells: 62.6;Proximal enterocytes: 49.9;Rod photoreceptor cells: 62.9"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"ASC diff: 28.5;ASC TERT1: 24.3;hTEC/SVTERT24-B: 15.3;hTERT-RPE1: 24.5;LHCN-M2: 15.4;U-87 MG: 26.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA063345			Uncertain	Vesicles	"Intracellular and membrane"	NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 86: Liver & Placenta - Transport via ER"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 45: Enterocytes - Digestion"	Vesicles		"HPA063345: AB_2684992"	"unprognostic (1.04e-2)"	"unprognostic (6.45e-2)"	"unprognostic (1.80e-1)"	"unprognostic (2.67e-1)"	"unprognostic (3.66e-2)"	"unprognostic (1.48e-2)"	"unprognostic (1.88e-2)"	"unprognostic (1.54e-1)"	"unprognostic (5.35e-2)"	"unprognostic (4.04e-2)"	"unprognostic (4.05e-1)"	"unprognostic (1.26e-3)"	"unprognostic (7.63e-2)"	"unprognostic (8.79e-2)"	"unprognostic (3.46e-2)"	"unprognostic (2.12e-3)"	"unprognostic (3.27e-2)"	94.5	1.8	2.2	4.1	2.5	1.0	34.2	2.2	2.6	2.5	3.5	13.6	18.5	4.2	7.8	3.1	4.6	4.2	9.2	2.0	2.2	9.0	58.9	1.9	1.8	2.7	2.5	2.1	3.5	0.3	1.7	0.6	2.4	4.4	4.4	3.2	3.3	2.2	6.1	2.7	15.5	19.5	2.5	2.2	5.9	2.4	2.8	0.9	2.7	7.6	0.7	5.5	2.2	3.4	0.7	1.4	0.8	0.5	28.5	24.3	0.6	3.8	4.2	0.7	1.4	0.5	7.9	1.0	0.7	2.1	0.2	0.3	0.3	0.1	0.6	1.0	1.3	0.1	2.0	2.1	0.8	0.1	0.3	10.5	1.0	15.3	0.1	24.5	0.3	0.5	0.2	1.3	15.4	0.7	0.4	0.2	0.3	3.7	2.3	0.6	0.4	0.5	0.2	0.8	0.2	1.1	0.2	0.5	3.4	0.2	0.7	0.6	0.5	1.5	1.5	1.1	0.9	1.1	0.5	0.2	26.7	0.4	0.3	0.0	0.1	0.5	0.0	0.1	0.0	0.1	0.2	0.5	0.2	0.0	0.2	0.0	0.2	0.3	0.2	0.5	0.0	0.0	2.2	2.5	2.2	2.6	2.0	2.2	2.7	2.5	2.4	2.5	2.8	3.4	2.5	9.6	2.2	0.0	4.6	1.9	4.5	3.9	0.6	24.3	2.7	5.0	3.9	10.0	2.4	1.8	62.6	2.2	5.3	23.5	1.9	2.1	0.8	1.8	2.9	3.7	11.5	0.0	0.0	2.6	1.2	3.9	11.2	1.5	0.0	4.9	3.6	18.4	0.6	16.8	0.0	10.3	0.0	4.5	7.9	2.3	13.4	2.3	5.4	0.0	4.7	8.2	12.3	0.0	0.0	3.6	18.6	6.8	0.7	3.2	49.9	13.0	4.7	62.9	13.1	14.0	9.3	3.9	6.4	0.8	1.7	1.5	4.8	5.3	15.9	3.1
RDH8	"PRRDH, SDR28C2"	ENSG00000080511	"Retinol dehydrogenase 8"	Q9NYR8	19	10013249-10022279	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Sensory transduction, Vision"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	37	"retina: 114.4"	"Cell type enhanced"	"Detected in some"		"Bipolar cells: 39.3;Cone photoreceptor cells: 54.2;Early spermatids: 72.6;Muller glia cells: 22.1;Rod photoreceptor cells: 203.4"	"Cancer enriched"	"Detected in some"	4	"melanoma: 2.2"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA064473			Approved	"Nucleoplasm,Midbody ring,Cytosol"		Yes	NA				"Cluster 79: Retina - Phototransduction"		"Cluster 46: Photoreceptor cells - Phototransduction"	Nucleoplasm	"Midbody ring, Cytosol"	"HPA064473: "			"unprognostic (4.12e-1)"		"unprognostic (2.22e-2)"	"unprognostic (1.08e-1)"	"unprognostic (9.98e-3)"		"unprognostic (4.58e-3)"	"unprognostic (2.66e-1)"	"unprognostic (1.45e-1)"			"unprognostic (1.02e-1)"	"unprognostic (3.86e-1)"		"unprognostic (2.63e-1)"	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	114.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.6	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	39.3	0.0	0.0	0.2	0.0	0.0	0.0	54.2	0.0	0.0	0.0	0.0	0.0	72.6	0.0	0.0	0.6	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	10.1	0.0	0.0	0.0	0.0	0.0	6.3	0.0	0.0	0.0	0.0	0.0	22.1	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	203.4	0.0	0.0	0.2	1.5	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0
RETSAT	FLJ20296	ENSG00000042445	"Retinol saturase"	Q6NUM9	2	85341955-85354531	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adipose tissue: 247.0"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 264.9;Proximal enterocytes: 249.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"ASC diff: 197.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA007961, HPA046513"	Uncertain		Uncertain	Nucleoli		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 45: Enterocytes - Digestion"	Nucleoli		"HPA007961: AB_1079802, HPA046513: AB_2679680"	"unprognostic (6.17e-2)"	"unprognostic (1.02e-1)"	"unprognostic (1.29e-1)"	"unprognostic (5.84e-3)"	"unprognostic (1.14e-1)"	"unprognostic (1.31e-1)"	"prognostic favorable (4.23e-4)"	"unprognostic (1.89e-1)"	"unprognostic (2.16e-1)"	"unprognostic (3.59e-2)"	"unprognostic (1.77e-2)"	"unprognostic (1.59e-1)"	"prognostic favorable (1.95e-10)"	"unprognostic (2.73e-2)"	"unprognostic (5.34e-1)"	"unprognostic (8.24e-3)"	"unprognostic (9.90e-2)"	247.0	52.3	16.5	17.6	20.9	3.8	63.9	19.8	15.8	18.9	27.3	89.6	167.0	16.0	38.4	36.9	15.7	32.0	20.3	14.9	20.0	54.9	115.9	24.6	11.7	21.0	20.0	17.0	37.5	36.9	7.2	11.6	20.0	32.5	73.5	9.5	27.8	23.6	68.3	48.8	142.4	22.0	19.2	11.7	60.9	14.6	19.9	12.2	47.4	55.1	19.9	19.0	23.7	23.7	52.7	30.1	16.8	40.0	197.8	37.0	22.1	37.8	46.5	22.5	31.5	20.9	36.2	18.5	30.3	29.6	17.9	42.6	22.9	65.6	21.6	22.8	15.9	9.0	23.5	50.6	47.6	17.9	19.3	48.6	87.2	28.7	38.1	51.4	37.6	15.4	9.7	43.1	42.0	11.0	12.5	9.0	5.6	52.6	36.2	8.1	33.7	23.9	39.1	30.1	8.3	13.8	31.4	59.9	101.8	11.2	28.2	2.9	30.0	25.3	13.8	23.5	19.9	23.0	22.9	7.2	30.9	20.5	17.6	0.0	3.8	1.8	4.8	4.0	6.2	2.6	3.5	6.0	4.0	1.5	2.5	2.5	3.7	5.1	8.7	2.7	4.2	3.4	16.5	20.9	19.8	15.8	14.9	20.0	21.0	20.0	20.0	19.2	19.9	23.7	7.3	28.9	29.6	5.9	4.5	11.3	10.8	18.6	12.5	3.7	13.0	7.9	21.7	21.5	15.5	12.9	18.8	10.9	4.3	264.9	0.0	23.7	27.6	9.7	6.8	9.7	10.8	2.5	5.7	36.1	6.5	9.0	56.1	16.6	10.8	5.5	7.5	54.7	9.9	11.8	4.5	45.0	8.2	10.4	8.6	60.0	14.6	7.4	30.2	7.5	8.3	8.3	10.3	6.6	12.1	32.7	79.2	12.4	10.3	11.8	249.9	17.8	11.9	4.9	0.0	7.7	8.8	2.9	3.1	24.9	14.9	8.5	7.7	9.9	56.6	9.8
RIOX1	"C14orf169, FLJ21802, JMJD9, MAPJD, NO66"	ENSG00000170468	"Ribosomal oxygenase 1"	Q9H6W3	14	73490933-73493394	"Enzymes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 9.1;dendritic cells: 8.0;Extravillous trophoblasts: 6.9;Hofbauer cells: 8.2;monocytes: 7.2;Proximal tubular cells: 7.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA003730			Supported	"Nucleoli rim"		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 7: Non-specific - Mitochondria"	"Nucleoli rim"		"HPA003730: AB_2667040"	"unprognostic (4.70e-3)"	"unprognostic (1.94e-2)"	"unprognostic (2.45e-1)"	"unprognostic (2.32e-1)"	"unprognostic (1.84e-3)"	"unprognostic (1.73e-1)"	"unprognostic (2.27e-2)"	"unprognostic (1.48e-1)"	"unprognostic (6.51e-2)"	"unprognostic (5.36e-2)"	"unprognostic (1.35e-3)"	"unprognostic (4.55e-2)"	"unprognostic (2.84e-3)"	"unprognostic (1.05e-1)"	"unprognostic (1.67e-1)"	"unprognostic (7.97e-3)"	"unprognostic (8.62e-2)"	3.8	4.2	5.1	5.1	4.5	7.8	3.7	6.5	5.0	3.7	4.6	4.5	3.9	5.3	4.8	5.5	4.4	2.4	4.9	4.5	4.9	4.2	6.8	3.9	6.7	4.3	4.1	3.8	6.4	5.4	3.5	2.8	4.1	3.3	3.7	1.9	4.6	3.8	3.6	4.0	5.1	4.0	3.7	5.6	4.9	13.6	4.9	9.4	3.4	3.0	6.9	4.5	3.3	5.7	17.5	15.5	9.9	15.3	12.5	7.0	19.0	11.7	8.5	11.8	10.6	13.5	8.8	29.7	8.4	10.1	9.9	20.4	19.1	11.6	9.8	19.0	21.0	18.7	9.0	9.0	6.9	0.0	24.1	7.6	10.6	11.4	5.2	7.5	10.8	17.0	13.8	10.7	10.7	27.6	33.1	21.4	10.8	15.1	26.0	26.1	15.4	9.0	11.8	12.9	20.5	14.8	19.4	34.4	12.7	9.8	34.4	18.6	15.6	0.0	19.5	10.2	0.1	14.6	16.9	10.2	5.2	15.3	11.8	0.1	1.3	3.4	3.7	2.3	4.3	2.3	3.6	2.9	1.8	1.6	3.3	2.5	0.5	3.2	1.4	3.1	1.7	0.8	5.1	4.5	6.5	5.0	4.5	4.9	4.3	4.1	4.1	3.7	4.9	5.7	2.9	3.2	1.1	0.0	2.0	0.0	0.0	0.0	0.0	0.0	5.4	3.2	0.0	0.0	3.1	5.5	0.0	9.1	8.0	0.0	5.9	3.8	0.0	4.2	4.0	2.1	0.0	0.0	0.0	5.7	6.9	1.5	0.0	4.7	2.5	5.2	0.0	0.0	8.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.7	0.0	0.0	7.2	0.0	0.0	0.0	0.0	3.4	0.0	0.0	1.2	0.0	0.0	7.6	0.0	0.0	0.0	0.0	2.2	0.0	0.0	0.0	0.0	1.4	3.4	3.5	0.0	0.0
RNLS	"C10orf59, FLJ11218, renalase"	ENSG00000184719	"Renalase, FAD dependent amine oxidase"	Q5VYX0	10	88273864-88584530	"Enzymes, Predicted secreted proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 103.0;Inhibitory neurons: 101.1;Oligodendrocyte precursor cells: 51.8;Oligodendrocytes: 61.8;Proximal tubular cells: 43.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"A-431: 18.3;fHDF/TERT166: 17.1;HSkMC: 19.5"					"Low region specificity"	"Detected in all"								"Secreted to blood"	NA	NA	10500000000		"Cluster 7: Monocytes - Unknown function"	"Cluster 1: Thyroid gland - Transcription"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"				"unprognostic (3.27e-2)"	"unprognostic (9.16e-2)"	"unprognostic (1.27e-1)"	"unprognostic (2.58e-1)"	"unprognostic (1.46e-3)"	"unprognostic (1.99e-1)"	"unprognostic (2.01e-1)"	"unprognostic (2.29e-1)"	"unprognostic (1.32e-1)"	"unprognostic (1.59e-1)"	"unprognostic (3.98e-1)"	"unprognostic (1.14e-1)"	"unprognostic (1.75e-2)"	"unprognostic (7.74e-3)"	"unprognostic (1.37e-2)"	"unprognostic (9.80e-2)"	"unprognostic (1.71e-1)"	7.1	13.4	2.0	2.8	2.4	2.2	6.7	6.1	3.5	7.4	7.2	7.6	5.5	5.0	5.3	4.9	6.1	5.5	11.8	2.0	2.9	16.6	8.7	3.0	3.8	5.0	6.6	5.8	8.2	9.0	5.3	2.0	5.2	7.0	8.3	4.8	6.0	3.9	11.8	4.3	5.6	3.5	3.4	2.8	6.7	5.3	2.7	2.5	9.1	9.8	4.0	4.7	4.4	3.2	18.3	8.2	0.3	0.1	2.4	2.8	0.0	5.1	0.5	2.7	2.3	1.0	5.2	0.0	8.0	17.1	0.0	2.4	0.0	0.9	2.2	3.8	0.1	2.9	5.1	0.2	11.2	0.0	0.5	19.5	1.4	10.2	0.1	0.3	5.7	0.1	1.4	9.2	0.1	6.3	0.0	3.5	0.0	0.0	0.0	2.1	0.0	0.0	0.0	1.1	4.3	0.1	0.1	4.0	12.4	4.9	2.2	8.9	1.3	2.5	4.1	6.3	3.9	5.3	8.4	0.2	0.0	9.8	0.0	0.0	2.1	1.2	2.3	3.6	1.7	2.4	1.7	1.6	3.1	2.2	1.8	1.4	0.1	2.7	2.3	2.7	0.9	1.8	2.0	2.4	6.1	3.5	2.0	2.9	5.0	6.6	5.2	3.4	2.7	3.2	1.2	3.2	1.5	32.0	5.5	3.2	6.8	5.7	4.0	6.5	5.5	3.9	16.7	4.3	5.8	1.8	2.1	2.0	3.2	6.2	23.5	6.4	8.9	3.8	3.1	1.3	5.4	4.6	103.0	9.6	0.5	6.2	7.1	3.2	1.3	2.2	2.5	10.1	6.5	5.0	101.1	5.5	2.0	4.7	3.8	4.3	1.5	3.8	3.6	40.3	3.7	6.8	3.1	51.8	61.8	4.2	8.9	6.4	3.9	4.4	8.5	43.1	1.6	5.7	0.0	4.6	4.6	4.7	8.2	10.4	5.5	1.6	3.0	2.9	7.2	6.9
RRM1		ENSG00000167325	"Ribonucleotide reductase catalytic subunit M1"	P23921	11	4094707-4138932	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"DNA replication"	"Allosteric enzyme, Oxidoreductase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Spermatocytes: 102.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB022093, HPA057265, HPA064297"	Enhanced		Supported	Cytosol		NA	Yes		140000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Cytosol		"CAB022093: , HPA057265: AB_2683386, HPA064297: AB_2685236"	"unprognostic (4.47e-2)"	"unprognostic (1.73e-2)"	"unprognostic (1.99e-3)"	"unprognostic (3.65e-1)"	"unprognostic (2.83e-1)"	"unprognostic (2.19e-1)"	"prognostic unfavorable (1.53e-4)"	"unprognostic (1.31e-2)"	"unprognostic (3.43e-2)"	"unprognostic (6.90e-2)"	"unprognostic (1.06e-3)"	"unprognostic (4.21e-2)"	"unprognostic (6.88e-3)"	"unprognostic (9.20e-3)"	"unprognostic (6.16e-2)"	"unprognostic (8.41e-2)"	"unprognostic (9.93e-3)"	16.6	21.2	5.1	24.8	5.3	32.8	22.7	7.1	6.1	16.9	4.7	25.7	19.3	16.2	10.1	26.5	15.5	11.8	16.4	5.1	5.7	13.4	18.4	12.8	34.4	6.1	5.5	16.4	14.6	24.7	7.1	20.4	6.6	18.5	29.4	23.6	14.7	16.0	30.3	36.1	20.2	20.1	6.2	13.0	17.6	17.9	5.1	56.7	15.6	30.0	45.2	15.6	18.9	6.2	221.6	117.8	188.4	110.0	28.4	56.2	73.0	198.0	98.2	220.7	225.9	106.8	163.8	237.4	47.0	100.1	95.9	173.0	176.9	143.2	259.3	117.3	187.9	121.0	159.8	83.1	11.2	208.9	84.6	26.6	37.8	121.7	86.4	48.3	107.8	140.1	161.1	107.3	186.8	99.6	246.7	41.9	118.2	152.2	119.2	196.1	147.0	84.3	59.4	61.8	159.8	88.1	175.1	104.8	30.0	75.8	102.8	71.4	62.3	203.4	106.0	206.9	147.4	70.3	103.5	252.5	114.1	137.6	130.3	8.3	4.0	4.5	11.3	11.2	21.1	9.2	22.3	16.6	7.3	5.2	17.2	15.0	0.0	10.5	15.6	4.4	41.7	10.3	5.1	5.3	7.1	6.1	5.1	5.7	6.1	5.5	6.6	6.2	5.1	6.2	12.4	19.2	14.4	4.9	17.0	33.4	26.8	31.0	17.6	15.6	15.1	14.4	33.5	14.3	24.7	18.4	6.2	62.8	14.9	13.3	7.9	25.6	69.9	11.5	14.5	15.7	18.0	81.2	11.2	22.2	62.5	22.0	20.4	13.9	7.0	27.3	10.8	15.0	28.3	18.5	12.0	25.0	16.2	11.7	10.3	83.9	13.1	13.9	10.6	6.5	10.7	24.0	5.2	12.1	11.9	15.8	10.4	16.6	31.3	10.1	12.5	8.4	15.5	22.7	13.1	19.5	27.1	102.8	63.1	36.5	29.0	39.7	23.2	18.1	34.3	20.6
RRM2	"C2orf48, FLJ25102"	ENSG00000171848	"Ribonucleotide reductase regulatory subunit M2"	P31350	2	10120698-10211725	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins"	"DNA replication"	Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"bone marrow: 44.2;esophagus: 18.4;intestine: 19.7;lymphoid tissue: 58.1"	"Group enriched"	"Detected in many"	4	"Erythroid cells: 214.0;Extravillous trophoblasts: 254.1;Plasma cells: 248.0"	"Low cancer specificity"	"Detected in all"			"Not detected"	"Not detected"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA056994	Enhanced		Supported	Cytosol		Yes	Yes		13000	"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Cytosol		"HPA056994: AB_2683304"	"unprognostic (2.10e-2)"	"unprognostic (1.62e-1)"	"unprognostic (6.40e-3)"	"unprognostic (4.42e-3)"	"unprognostic (5.70e-2)"	"unprognostic (1.69e-1)"	"prognostic unfavorable (1.39e-5)"	"unprognostic (1.04e-3)"	"unprognostic (6.67e-3)"	"unprognostic (4.53e-2)"	"prognostic unfavorable (1.62e-4)"	"unprognostic (5.11e-3)"	"prognostic unfavorable (0.00e+0)"	"unprognostic (3.05e-2)"	"unprognostic (2.24e-1)"	"unprognostic (1.38e-1)"	"unprognostic (2.09e-2)"	1.5	1.3	0.3	12.4	0.3	44.2	2.9	0.5	0.4	3.0	1.9	14.2	9.4	2.2	0.7	18.4	0.8	1.1	0.5	0.3	0.3	0.9	3.2	2.4	35.5	0.4	0.4	0.3	1.1	0.3	0.2	4.6	0.4	0.9	19.7	0.2	2.1	0.5	0.1	3.7	7.5	6.1	0.3	11.1	6.0	2.9	0.8	58.1	0.9	0.1	37.6	6.0	4.6	0.5	110.2	25.0	127.1	49.9	7.4	22.5	116.8	209.2	128.6	170.2	187.9	70.8	59.1	114.4	9.5	88.6	151.1	55.0	188.0	136.6	198.0	210.7	41.8	146.3	52.1	105.1	0.8	146.7	87.4	8.1	3.4	234.6	16.2	27.7	103.3	110.4	63.4	328.6	214.3	57.1	167.3	90.9	83.0	133.3	103.6	87.6	187.0	67.8	87.1	62.7	67.7	56.2	198.0	116.6	17.3	51.8	69.2	31.4	57.6	93.1	125.1	66.9	289.6	212.1	184.9	195.9	51.0	134.4	107.7	0.3	0.1	0.1	1.2	0.0	0.0	0.1	0.3	0.8	0.1	0.1	0.1	0.4	0.4	0.8	0.0	0.1	0.2	0.2	0.3	0.3	0.5	0.4	0.3	0.3	0.4	0.4	0.4	0.3	0.8	0.5	0.2	3.2	1.5	0.0	25.0	10.5	3.0	9.2	1.2	0.0	3.9	4.4	1.4	1.5	2.3	0.0	0.0	42.3	5.6	12.9	1.9	1.2	3.9	2.2	3.5	4.2	0.0	214.0	0.1	0.0	254.1	11.2	11.7	3.6	5.7	12.2	3.9	3.7	47.9	0.0	0.0	26.9	2.0	7.2	8.8	6.8	0.3	5.0	0.0	1.0	0.0	0.0	7.2	0.0	0.0	0.5	0.3	0.4	248.0	1.5	2.4	2.1	4.6	0.0	0.0	0.2	14.6	22.9	34.0	51.5	1.6	48.7	11.9	1.2	36.7	5.6
RRM2B	p53R2	ENSG00000048392	"Ribonucleotide reductase regulatory TP53 inducible subunit M2B"	Q7LG56	8	102204502-102238961	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"DNA damage, DNA repair, DNA replication"	Oxidoreductase	"Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB006854, HPA028812"	Approved		Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 65: Plasmacytoid DCs - Unknown function"	"Nucleoplasm, Cytosol"		"CAB006854: , HPA028812: AB_10602246"	"unprognostic (7.76e-3)"	"unprognostic (4.14e-2)"	"unprognostic (9.41e-3)"	"unprognostic (3.41e-1)"	"unprognostic (1.13e-2)"	"unprognostic (1.28e-1)"	"unprognostic (5.51e-2)"	"unprognostic (1.35e-2)"	"unprognostic (1.66e-1)"	"unprognostic (9.40e-2)"	"unprognostic (1.74e-2)"	"unprognostic (1.03e-1)"	"unprognostic (1.70e-2)"	"unprognostic (4.32e-1)"	"unprognostic (1.47e-1)"	"unprognostic (2.52e-1)"	"unprognostic (7.17e-2)"	11.5	21.2	10.5	11.5	12.1	7.1	12.1	13.6	11.5	12.5	26.5	15.3	15.0	11.6	15.1	11.2	13.5	11.9	16.7	10.1	13.7	24.4	22.6	22.0	20.1	13.6	12.4	12.0	13.5	45.0	10.3	13.8	13.9	15.7	15.5	21.9	10.9	13.8	30.4	11.0	10.1	11.7	14.1	14.3	9.5	9.7	12.6	10.1	39.9	34.9	19.6	11.2	5.4	16.8	15.3	26.5	30.7	18.3	43.7	41.3	24.6	34.8	41.4	18.1	21.0	9.6	11.9	97.5	31.8	38.7	18.5	5.7	15.1	35.2	25.3	15.8	16.2	24.4	10.3	20.9	35.3	7.6	50.0	53.1	66.1	20.2	30.5	43.0	51.8	16.3	18.2	14.6	59.1	15.2	13.1	14.6	17.7	16.5	19.2	8.2	12.7	20.1	43.1	17.1	7.8	15.4	17.9	9.7	21.1	76.3	25.5	17.1	39.4	27.8	53.7	19.6	9.6	15.3	15.3	88.0	41.0	11.5	30.2	15.7	6.3	7.0	2.7	5.4	3.8	6.6	2.3	3.2	7.7	8.6	2.6	2.8	23.1	4.1	11.5	2.2	1.8	3.3	10.5	12.1	13.6	11.5	10.1	13.7	13.6	12.4	13.9	14.1	12.6	16.8	16.2	57.7	29.3	10.1	33.5	19.4	8.2	11.8	34.1	13.5	17.0	9.4	22.8	20.0	23.9	40.5	14.6	13.8	13.9	7.3	25.4	6.8	2.3	36.2	11.1	14.9	29.4	3.8	14.6	8.2	5.9	14.8	6.1	11.8	11.4	11.2	18.5	23.6	12.6	10.1	17.6	9.7	10.2	26.2	39.5	1.4	14.3	23.8	17.8	20.6	18.2	24.5	7.2	16.1	12.1	5.7	5.7	14.7	9.3	10.7	8.1	22.7	39.9	18.3	6.6	16.2	16.8	13.2	14.5	26.2	18.5	4.8	12.2	8.6	12.1	6.7
SARDH	"DMGDHL1, SDH"	ENSG00000123453	"Sarcosine dehydrogenase"	Q9UL12	9	133663560-133739955	"Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"epididymis: 47.9;liver: 114.4;pancreas: 43.2"	"Cell type enriched"	"Detected in some"	5	"Hepatocytes: 120.6"	"Cancer enriched"	"Detected in many"	8	"liver cancer: 18.7"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	5	"memory CD4 T-cell: 3.3;naive CD4 T-cell: 6.7;T-reg: 8.8"	"Lineage enriched"	"Detected in single"	16	"T-cells: 8.8"	"Cell line enhanced"	"Detected in many"		"AN3-CA: 17.4;Hep G2: 31.1;MOLT-4: 22.5;RH-30: 18.5;RPMI-8226: 39.1;SH-SY5Y: 14.7"	"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"HPA057267, HPA058086"	Approved		Approved	Mitochondria		NA	NA		230000	"Cluster 20: T-cells - T-cell receptor"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Mitochondria		"HPA057267: AB_2683388, HPA058086: AB_2683601"	"unprognostic (3.64e-2)"	"unprognostic (4.87e-2)"	"unprognostic (2.31e-2)"	"unprognostic (1.38e-1)"	"prognostic unfavorable (4.62e-4)"	"unprognostic (5.83e-2)"	"unprognostic (1.42e-3)"	"unprognostic (2.21e-1)"	"unprognostic (1.58e-1)"	"unprognostic (1.43e-1)"	"unprognostic (2.23e-1)"	"unprognostic (1.74e-1)"	"unprognostic (7.74e-3)"	"unprognostic (2.78e-1)"	"unprognostic (3.48e-1)"	"unprognostic (9.73e-2)"	"unprognostic (1.30e-2)"	1.1	2.2	3.6	2.5	3.5	0.9	0.8	1.9	3.9	2.6	0.7	1.1	1.8	2.0	47.9	0.6	1.9	1.3	2.4	3.3	3.5	12.0	114.4	2.6	4.1	4.4	3.1	3.0	43.2	2.1	4.1	0.9	3.4	2.3	0.4	0.6	5.3	1.8	0.6	0.4	1.3	0.9	2.9	1.3	3.0	0.7	4.2	4.3	1.6	0.3	2.4	1.1	1.0	3.1	0.0	0.1	1.4	17.4	0.1	0.5	2.3	0.1	0.7	0.9	1.1	0.3	0.2	0.0	2.4	0.3	2.2	0.1	0.0	0.3	0.7	0.0	0.3	2.5	0.0	31.1	1.9	0.1	0.3	4.2	0.0	2.0	0.1	0.4	0.2	13.1	0.1	0.4	11.1	3.2	22.5	2.4	2.8	1.7	0.2	1.6	18.5	39.1	0.0	0.1	1.7	14.7	0.0	0.4	3.9	0.8	2.4	0.2	0.1	3.3	3.0	0.3	0.0	0.3	0.0	1.3	2.1	1.4	0.1	0.3	0.1	0.1	0.3	0.0	0.8	0.0	3.3	0.8	0.0	0.3	6.7	1.2	0.5	0.1	0.0	0.3	8.8	1.4	3.6	3.5	1.9	3.9	3.3	3.5	4.4	3.1	3.4	2.9	4.2	3.1	0.1	0.0	1.9	6.8	0.4	0.3	0.4	0.0	1.2	0.1	0.2	0.8	0.8	0.0	0.0	1.8	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.1	1.0	0.8	1.2	5.7	1.5	1.1	0.1	2.3	0.0	0.3	1.3	0.8	2.9	120.6	0.1	0.0	0.7	0.0	0.0	1.6	0.6	0.8	4.7	0.2	0.0	1.9	0.0	4.2	1.0	0.5	0.3	0.1	0.0	3.0	0.7	0.3	0.0	21.3	0.0	0.3	0.0	1.6	3.5	0.1	0.8	0.0	0.1	0.0	4.2	1.6	0.0	0.2
SC5D	SC5DL	ENSG00000109929	Sterol-C5-desaturase	O75845	11	121292681-121313410	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 393.6"	"Cell type enhanced"	"Detected in all"		"Hepatic stellate cells: 141.0;Hepatocytes: 307.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA066283, HPA070248"	Enhanced		Approved	"Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol"		No	No			"Cluster 44: Non-specific - Transcription"	"Cluster 85: Liver - Metabolism"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 15: Hepatocytes - Hemostasis"	"Nucleoplasm, Endoplasmic reticulum"	"Plasma membrane, Cytosol"	"HPA066283: AB_2685648, HPA070248: AB_2686240"	"unprognostic (4.78e-2)"	"unprognostic (7.29e-2)"	"unprognostic (2.26e-2)"	"unprognostic (2.36e-1)"	"unprognostic (3.98e-2)"	"prognostic unfavorable (3.30e-4)"	"unprognostic (2.79e-2)"	"unprognostic (7.96e-2)"	"prognostic unfavorable (3.98e-4)"	"unprognostic (4.03e-2)"	"unprognostic (3.18e-2)"	"unprognostic (1.01e-1)"	"prognostic favorable (1.07e-7)"	"unprognostic (4.29e-2)"	"unprognostic (2.51e-1)"	"unprognostic (2.29e-1)"	"unprognostic (1.98e-1)"	28.6	35.3	18.4	12.6	20.4	5.7	56.6	37.1	29.3	20.7	17.6	23.2	48.2	15.1	73.2	39.6	16.5	18.2	22.0	19.9	29.9	49.1	393.6	24.6	13.5	42.9	28.0	16.9	21.5	48.6	15.6	14.7	39.1	101.4	19.9	29.5	22.4	56.6	7.7	13.8	24.7	16.2	32.2	8.8	21.7	24.3	24.6	13.5	23.9	13.0	19.5	21.5	27.1	36.5	26.5	14.3	184.8	39.5	72.1	59.9	27.8	27.8	53.5	18.2	32.4	83.1	95.9	25.4	89.0	32.3	156.6	100.8	59.2	70.9	18.1	12.5	80.0	34.6	73.4	64.4	57.9	24.8	12.5	51.0	57.4	60.4	60.2	15.6	29.8	22.8	25.0	34.6	89.0	27.4	9.4	29.2	59.8	74.4	39.7	13.2	51.0	21.6	133.6	116.5	51.1	28.8	73.4	14.6	38.0	125.4	62.2	38.6	58.3	19.0	29.7	32.5	14.0	6.4	11.2	33.3	7.0	49.5	33.5	7.8	3.7	1.0	3.5	4.9	5.9	4.4	4.7	4.2	6.5	4.1	6.8	6.7	0.3	5.3	3.6	7.7	5.5	2.6	18.4	20.4	37.1	29.3	19.9	29.9	42.9	28.0	39.1	32.2	24.6	36.5	10.4	19.2	31.9	23.8	62.6	9.7	49.9	48.9	14.8	26.8	33.7	12.4	20.8	18.6	40.8	20.2	31.3	15.9	47.5	26.4	5.9	24.1	3.0	11.5	8.8	15.7	14.4	18.1	29.6	28.9	16.7	16.3	18.3	19.6	17.7	11.1	141.0	307.1	21.0	23.5	29.4	15.3	59.0	22.1	17.0	1.3	19.3	17.6	19.6	20.6	15.6	38.7	13.4	27.6	34.0	19.3	18.8	17.0	20.9	50.1	24.1	15.8	18.7	28.3	13.1	12.9	14.7	6.7	12.7	36.2	15.5	18.6	56.5	42.8	13.3	54.4
SCD	"FADS5, SCDOS"	ENSG00000099194	"Stearoyl-CoA desaturase"	O00767	10	100347233-100364826	"Enzymes, Metabolic proteins, Predicted membrane proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adipose tissue: 1233.7;brain: 839.9;liver: 583.8"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 389.6;Granulosa cells: 187.3;Hepatocytes: 840.3;Oligodendrocytes: 451.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in all"		"ASC diff: 2534.2;CAPAN-2: 1824.4"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"HPA012107, HPA063921"	Approved		Enhanced	"Endoplasmic reticulum"		No	Yes			"Cluster 7: Monocytes - Unknown function"	"Cluster 15: Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 15: Hepatocytes - Hemostasis"	"Endoplasmic reticulum"		"HPA012107: AB_1856610, HPA063921: AB_2685154"	"unprognostic (2.10e-1)"	"unprognostic (2.62e-3)"	"unprognostic (7.86e-2)"	"unprognostic (5.19e-2)"	"unprognostic (1.24e-1)"	"unprognostic (6.16e-2)"	"unprognostic (1.13e-1)"	"unprognostic (3.88e-2)"	"unprognostic (6.53e-2)"	"unprognostic (2.72e-1)"	"unprognostic (1.47e-1)"	"unprognostic (1.69e-1)"	"prognostic unfavorable (7.56e-5)"	"unprognostic (7.18e-2)"	"unprognostic (3.27e-1)"	"unprognostic (4.73e-2)"	"prognostic unfavorable (7.79e-5)"	1233.7	131.2	408.7	25.7	525.8	23.0	261.5	535.7	522.1	43.2	156.6	42.9	93.1	15.4	25.5	107.8	5.0	28.7	47.1	349.1	457.5	18.5	583.8	142.8	17.2	775.0	508.9	49.6	22.6	79.5	10.3	19.9	637.8	100.1	39.7	17.9	112.6	11.2	6.1	27.0	36.0	15.9	574.4	15.3	25.2	51.8	538.7	18.4	13.0	7.2	21.0	22.5	41.9	839.9	411.2	373.3	777.6	536.4	2534.2	1449.4	158.2	43.4	948.3	101.6	536.6	323.8	1824.4	173.3	33.7	102.2	461.8	716.4	433.7	1549.5	88.9	59.4	179.6	97.5	219.3	653.4	488.4	136.9	100.9	795.5	459.4	395.0	688.9	273.1	196.2	375.3	275.4	513.3	41.7	646.8	155.9	163.3	270.7	120.7	106.3	72.6	287.4	550.4	443.8	455.3	48.9	185.3	85.8	399.7	834.9	224.2	447.7	291.3	79.0	10.0	115.9	9.1	89.8	141.4	81.5	262.9	184.4	416.0	65.9	0.0	0.8	0.0	1.4	1.6	2.3	0.6	0.5	0.7	2.7	0.9	0.4	1.3	0.1	1.4	0.0	1.5	0.0	1.2	408.7	525.8	535.7	522.1	349.1	457.5	775.0	508.9	637.8	574.4	538.7	839.9	3.8	54.5	389.6	34.0	15.7	3.7	4.5	121.8	0.6	6.5	16.1	6.2	11.2	28.6	66.2	0.0	6.2	3.0	4.7	21.5	0.0	14.6	52.6	13.9	9.0	12.5	25.8	15.8	4.8	67.9	71.7	15.9	25.0	26.9	6.3	187.3	32.9	840.3	34.1	26.9	5.2	16.4	52.9	113.5	4.2	93.0	3.7	21.2	58.7	8.4	10.2	11.9	2.1	18.6	451.5	29.6	2.7	1.5	3.7	31.4	16.2	4.9	31.0	6.2	0.0	3.6	25.7	2.0	1.2	26.7	2.3	17.4	6.6	97.8	38.9	8.2
SCD5	"ACOD4, FADS4, FLJ21032, HSCD5, SCD4"	ENSG00000145284	"Stearoyl-CoA desaturase 5"	Q86SK9	4	82629539-82798796	"Enzymes, Metabolic proteins, Predicted membrane proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adrenal gland: 156.7;brain: 353.6"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 248.4;Oligodendrocyte precursor cells: 892.7;Oligodendrocytes: 513.6"	"Group enriched"	"Detected in all"	6	"glioma: 152.4;thyroid cancer: 38.5"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"BJ: 69.2;RPTEC TERT1: 90.1"					"Low region specificity"	"Detected in all"			HPA042380	Uncertain					NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 70: Brain - Nervous system development"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 68: Oligodendrocytes - Mixed function"			"HPA042380: AB_10794797"	"unprognostic (3.23e-2)"	"unprognostic (3.84e-2)"	"unprognostic (2.86e-1)"	"unprognostic (6.98e-2)"	"unprognostic (1.58e-1)"	"unprognostic (2.95e-1)"	"unprognostic (2.83e-1)"	"unprognostic (3.82e-2)"	"unprognostic (6.82e-2)"	"unprognostic (3.22e-1)"	"unprognostic (1.04e-1)"	"unprognostic (2.37e-2)"	"prognostic favorable (2.32e-5)"	"unprognostic (1.28e-1)"	"unprognostic (1.26e-1)"	"unprognostic (3.88e-3)"	"unprognostic (2.92e-2)"	6.8	156.7	226.1	3.7	283.7	2.9	5.7	302.5	260.4	10.6	85.2	12.9	4.5	12.5	97.6	5.8	18.7	9.3	8.1	212.6	277.4	33.1	2.5	15.0	3.0	353.6	272.7	93.7	40.9	18.7	31.4	7.5	291.0	12.7	4.0	70.2	18.0	24.3	1.3	8.2	6.0	12.0	314.1	4.5	10.6	33.3	255.6	10.6	35.5	4.2	4.4	7.7	8.7	316.2	11.2	7.1	36.0	18.6	19.7	12.5	0.6	69.2	33.9	29.7	22.8	0.5	1.7	22.5	23.5	14.5	8.0	19.9	10.6	7.6	37.0	4.4	4.7	1.0	8.1	0.7	2.9	10.0	6.9	10.0	30.6	5.9	5.2	30.5	48.4	25.8	1.3	2.2	15.6	4.4	42.6	2.1	2.6	0.2	5.0	35.6	21.5	17.9	90.1	11.2	20.1	11.5	11.4	0.5	6.8	3.5	1.3	5.0	59.5	31.5	18.1	11.9	18.9	6.0	2.5	2.2	15.3	10.5	9.0	1.9	0.6	0.1	3.9	0.2	2.5	0.2	0.8	2.3	0.3	0.4	0.7	2.6	0.7	1.1	0.4	0.7	0.2	1.2	226.1	283.7	302.5	260.4	212.6	277.4	353.6	272.7	291.0	314.1	255.6	316.2	1.4	44.8	3.9	248.4	0.8	10.7	16.5	16.3	5.7	101.4	6.8	4.8	2.9	27.1	25.7	27.6	25.0	1.9	3.9	0.4	13.7	79.7	115.0	13.5	9.3	7.7	7.7	0.0	84.3	46.9	0.2	16.8	2.6	14.8	0.0	10.5	10.4	0.2	1.1	101.0	107.0	0.3	10.2	1.3	3.3	100.3	55.0	1.8	3.6	23.4	1.9	145.3	4.1	892.7	513.6	8.9	0.0	58.3	0.7	11.3	0.2	20.4	13.0	14.6	6.6	3.6	11.5	2.9	3.7	2.7	7.2	0.1	3.2	137.4	2.0	9.3
SDHA	"FP, SDH2, SDHF"	ENSG00000073578	"Succinate dehydrogenase complex flavoprotein subunit A"	P31040	5	218241-257082	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters"	"Electron transport, Transport, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Primary mitochondrial disease, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 601.0;skeletal muscle: 479.0"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"											"CAB034929, HPA041981, HPA064582"	Enhanced		Supported	Nucleoli,Mitochondria		No	No		360000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 20: HeLa - Mitochondria"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria	Nucleoli	"CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293"	"prognostic unfavorable (6.00e-4)"	"unprognostic (1.93e-1)"	"unprognostic (5.97e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.89e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.80e-1)"	"unprognostic (3.14e-2)"	"unprognostic (2.88e-1)"	"unprognostic (1.67e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.24e-1)"	"prognostic favorable (9.53e-8)"	"unprognostic (1.11e-2)"	"unprognostic (2.62e-1)"	"unprognostic (3.57e-1)"	"unprognostic (1.79e-1)"	70.6	148.0	60.5	29.6	62.7	38.4	65.8	78.7	71.3	50.2	63.2	131.9	148.9	53.2	27.3	67.1	50.3	33.9	601.0	60.8	73.4	139.1	276.8	54.3	43.1	74.1	62.7	65.8	71.5	122.9	44.8	28.8	75.7	46.3	82.1	42.7	66.8	35.6	479.0	58.9	116.8	36.1	61.7	66.4	115.6	56.4	71.7	41.8	49.6	224.8	36.5	63.2	56.3	63.7	88.4	154.2	54.8	95.0	96.9	68.5	154.1	63.3	81.8	107.2	108.4	163.9	115.9	108.3	218.6	70.2	92.1	111.8	102.4	129.7	66.3	241.9	98.9	50.1	390.8	224.1	60.0	69.5	70.7	70.6	84.3	83.6	33.7	93.6	123.9	83.5	84.6	83.1	48.7	155.8	93.9	206.9	19.3	101.4	193.5	119.0	84.6	223.2	245.4	122.7	62.3	35.4	332.5	205.5	90.7	36.1	115.0	93.2	91.1	80.3	82.1	48.2	52.5	93.0	40.9	79.8	81.6	99.9	52.5	66.6	70.8	88.1	95.2	85.7	86.8	79.5	92.5	94.5	93.3	73.3	89.2	85.0	14.1	85.5	74.7	59.5	149.3	111.3	60.5	62.7	78.7	71.3	60.8	73.4	74.1	62.7	75.7	61.7	71.7	63.7	29.4	35.3	71.1	20.2	50.9	61.2	81.4	105.8	31.3	51.0	24.6	17.0	272.6	64.3	78.5	75.4	102.2	109.6	39.3	169.7	142.8	94.7	58.7	39.1	30.1	39.1	47.5	56.8	34.4	44.9	102.8	49.4	47.9	48.5	43.7	64.8	47.5	167.0	67.5	101.0	39.9	96.3	105.8	41.0	55.0	28.8	68.3	38.8	90.7	12.2	60.2	50.7	52.5	19.1	37.9	54.2	100.1	55.7	67.5	37.0	274.4	190.7	75.2	87.2	78.9	33.2	51.7	96.9	54.3	40.9	35.9	154.7	56.7	85.0	160.1	88.2
SDHB	"SDH, SDH1"	ENSG00000117118	"Succinate dehydrogenase complex iron sulfur subunit B"	P21912	1	17018722-17054032	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters"	"Electron transport, Transport, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 491.5;tongue: 580.6"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 405.5;Proximal tubular cells: 449.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002868, CAB009822, CAB068233, CAB068234, CAB068235"	Enhanced		Supported	"Nucleoplasm,Plasma membrane,Mitochondria"	"Intracellular and membrane"	NA	NA		7900	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria	"Nucleoplasm, Plasma membrane"	"CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889"	"unprognostic (1.06e-1)"	"unprognostic (2.86e-2)"	"unprognostic (2.19e-2)"	"unprognostic (2.93e-2)"	"unprognostic (1.88e-1)"	"unprognostic (2.79e-3)"	"unprognostic (1.58e-1)"	"unprognostic (3.02e-1)"	"unprognostic (1.19e-1)"	"unprognostic (8.45e-2)"	"unprognostic (5.51e-2)"	"unprognostic (3.93e-2)"	"prognostic favorable (2.93e-7)"	"unprognostic (1.46e-1)"	"unprognostic (2.75e-1)"	"unprognostic (7.82e-2)"	"unprognostic (3.82e-2)"	85.8	95.7	68.0	59.0	72.2	94.6	68.7	80.6	84.3	56.8	81.1	134.3	163.0	56.0	71.0	77.4	59.8	48.0	302.8	69.9	76.9	228.0	336.1	56.1	75.3	74.8	71.4	44.4	80.3	144.3	42.8	57.6	73.8	55.7	132.4	62.9	74.0	60.5	491.5	55.6	121.9	70.4	73.9	60.5	92.8	64.4	74.9	62.7	64.3	580.6	84.2	71.3	52.0	78.9	157.3	152.7	72.2	107.8	141.6	135.2	95.9	122.4	145.2	254.3	227.7	216.8	183.1	206.8	159.3	156.4	176.1	180.1	290.7	226.8	284.8	128.7	280.6	183.4	149.2	168.2	172.8	276.0	135.6	140.4	154.9	224.5	370.1	138.7	183.6	176.5	165.2	236.9	179.6	129.5	182.4	175.1	70.4	224.6	302.6	146.1	142.5	265.4	252.4	88.7	157.5	86.0	172.3	216.3	392.3	76.4	131.1	169.1	94.9	115.8	131.0	206.4	176.0	98.9	133.3	198.6	170.4	438.5	128.3	68.7	149.8	149.5	71.4	206.5	70.7	89.9	81.0	77.5	186.8	81.1	73.5	74.8	174.3	85.3	185.7	89.3	113.8	116.1	68.0	72.2	80.6	84.3	69.9	76.9	74.8	71.4	73.8	73.9	74.9	78.9	48.2	64.1	47.4	20.9	57.4	52.1	93.3	199.8	40.5	31.5	45.2	49.4	405.5	101.5	97.0	47.8	14.6	107.1	48.3	176.1	354.1	134.3	220.3	48.7	38.2	54.7	48.6	77.3	27.7	149.2	142.2	62.0	46.9	45.5	66.6	39.9	46.8	226.0	177.4	37.0	32.1	103.1	116.0	88.7	67.9	30.5	57.8	78.4	64.0	29.0	123.1	78.3	48.4	15.6	24.6	111.5	218.3	67.7	62.2	74.4	300.5	449.0	79.8	53.8	39.5	57.1	191.6	148.9	71.5	72.9	54.6	121.8	46.8	69.3	162.0	110.9
SDR16C5	"EPHD-2, RDH-E2, RDHE2"	ENSG00000170786	"Short chain dehydrogenase/reductase family 16C member 5"	Q8N3Y7	8	56300005-56320776	"Enzymes, Metabolic proteins, Predicted membrane proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 51.9;lung: 34.4;skin 1: 62.6"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 155.9;Basal respiratory cells: 325.1;Club cells: 141.9;Ionocytes: 120.1;Pancreatic endocrine cells: 99.5;Respiratory ciliated cells: 82.5;Suprabasal keratinocytes: 72.2"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	35	"memory B-cell: 4.7;naive B-cell: 2.3"	"Lineage enriched"	"Detected in single"	47	"B-cells: 4.7"	"Cell line enhanced"	"Detected in some"		"CAPAN-2: 20.8;HaCaT: 10.3;hTCEpi: 16.7;OE19: 24.8;T-47d: 8.0"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA025224	Enhanced					NA	NA			"Cluster 19: B-cells - Humoral immune response"	"Cluster 11: Squamous epithelial cells - Epithelial cell function"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"			"HPA025224: AB_1856163"	"unprognostic (1.66e-1)"	"unprognostic (8.88e-2)"	"unprognostic (9.46e-2)"	"unprognostic (4.18e-4)"	"unprognostic (8.83e-3)"	"prognostic favorable (7.88e-4)"		"unprognostic (1.66e-1)"	"unprognostic (2.51e-1)"	"unprognostic (2.42e-1)"	"unprognostic (1.78e-3)"	"unprognostic (2.39e-1)"	"unprognostic (2.48e-5)"	"unprognostic (2.55e-1)"	"unprognostic (8.17e-2)"	"unprognostic (1.29e-1)"	"unprognostic (1.71e-1)"	0.3	0.2	1.7	3.0	1.8	0.0	9.1	1.6	4.4	15.6	0.5	2.2	2.3	0.0	0.0	51.9	0.2	0.4	0.2	2.2	1.5	0.1	0.0	34.4	0.4	4.8	2.0	0.2	0.4	0.0	0.5	0.0	4.9	0.3	3.9	1.1	16.8	0.0	0.3	62.6	15.7	0.2	0.9	0.0	18.1	0.8	2.8	0.3	0.0	0.2	21.9	6.3	24.9	1.8	4.2	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	20.8	0.0	0.0	0.0	0.0	10.3	0.0	0.9	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	16.7	0.0	2.3	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	24.8	1.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.5	0.0	0.0	8.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.7	0.0	0.0	0.0	2.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.7	1.8	1.6	4.4	2.2	1.5	4.8	2.0	4.9	0.9	2.8	1.8	1.7	48.1	155.9	0.0	1.7	51.1	6.2	325.1	4.6	0.3	5.5	2.4	0.2	5.7	141.9	0.0	0.0	0.0	0.0	7.1	0.0	0.7	0.4	0.0	0.1	2.3	0.0	0.0	4.3	1.4	0.0	0.9	10.2	0.1	3.8	0.0	0.0	0.0	0.0	0.0	1.1	19.7	120.1	0.0	3.6	0.4	0.6	0.4	3.6	0.0	0.6	12.3	0.0	0.0	0.3	99.5	3.4	0.0	0.0	9.5	0.3	0.0	82.5	1.6	0.0	0.1	4.9	0.3	5.5	36.6	72.2	0.0	0.6	0.0	5.3	26.0
SELENBP1	"hSBP, hSP56, LPSB"	ENSG00000143416	"Selenium binding protein 1"	Q13228	1	151364304-151372707	"Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Protein transport, Transport"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"intestine: 509.3"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 525.6;Distal enterocytes: 1056.9;Erythroid cells: 590.9;Hepatocytes: 501.5;Paneth cells: 451.4;Undifferentiated cells: 452.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"myeloid DC: 2.4"	"Lineage enhanced"	"Detected in single"		"dendritic cells: 2.4"	"Cell line enhanced"	"Detected in many"		"ASC diff: 144.9;HEL: 120.5;HSkMC: 75.9;OE19: 92.8;SK-BR-3: 274.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA005741, CAB008366, HPA011731"	Enhanced		Supported	Nucleoli		NA	NA		59000000	"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Nucleoli		"CAB008366: AB_592677, HPA005741: AB_1856662, HPA011731: AB_1856663"	"unprognostic (1.51e-1)"	"unprognostic (7.01e-2)"	"unprognostic (8.52e-3)"	"unprognostic (6.25e-3)"	"unprognostic (6.28e-2)"	"prognostic favorable (6.63e-4)"	"unprognostic (1.08e-2)"	"unprognostic (1.21e-2)"	"unprognostic (3.78e-3)"	"unprognostic (2.86e-1)"	"unprognostic (1.46e-1)"	"unprognostic (2.60e-1)"	"unprognostic (2.67e-2)"	"unprognostic (6.98e-2)"	"unprognostic (1.95e-1)"	"unprognostic (1.86e-2)"	"unprognostic (6.86e-3)"	128.3	18.7	49.8	24.9	53.0	95.9	76.3	45.5	54.8	57.0	47.4	509.3	74.7	31.3	43.4	31.8	132.7	52.2	69.1	47.1	48.2	77.2	261.7	181.0	10.9	47.8	51.0	49.4	29.0	11.9	15.0	20.4	46.5	44.2	471.7	3.9	61.6	48.8	72.9	25.2	94.2	49.5	46.9	51.1	126.4	6.1	51.0	7.1	115.1	138.1	6.8	58.3	29.3	45.7	0.0	17.2	31.9	1.8	144.9	59.1	8.4	5.9	2.6	3.1	6.5	18.1	5.4	0.0	30.7	10.7	0.0	0.4	0.0	0.4	2.8	0.1	14.8	120.5	53.1	28.9	30.5	0.2	0.0	75.9	1.0	5.3	0.1	0.4	19.0	0.0	12.4	0.0	8.0	13.2	0.0	0.0	26.6	92.8	32.2	0.1	1.7	0.7	7.1	0.0	0.4	0.7	0.5	274.4	0.0	25.1	49.4	1.8	1.8	0.0	1.1	16.8	0.1	0.1	0.0	0.1	0.0	0.6	0.0	0.0	0.6	0.0	0.0	0.4	0.0	0.0	0.0	0.0	2.4	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	2.2	49.8	53.0	45.5	54.8	47.1	48.2	47.8	51.0	46.5	46.9	51.0	45.7	36.6	294.9	525.6	38.2	4.0	10.8	27.7	56.4	30.7	0.3	73.0	59.9	135.7	75.8	123.9	5.5	0.0	2.4	1.9	1056.9	115.4	17.1	0.7	30.9	14.9	27.5	155.0	590.9	0.1	9.1	2.1	85.2	163.6	14.1	27.3	10.9	26.0	501.5	15.3	0.0	0.1	137.2	79.3	39.6	12.4	4.2	66.5	3.9	33.8	13.1	0.2	37.4	0.0	0.0	2.0	6.5	451.4	80.9	0.8	25.6	251.0	148.3	101.5	1.4	52.6	15.6	102.3	0.1	0.3	22.7	9.9	4.0	5.7	30.5	452.4	71.0
SELENOT	SELT	ENSG00000198843	"Selenoprotein T"	P62341	3	150602875-150630445	"Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 215.1;Extravillous trophoblasts: 230.6;Hofbauer cells: 238.8;Pancreatic endocrine cells: 206.0;Proximal tubular cells: 176.8;Syncytiotrophoblasts: 489.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA039780	Approved					NA	NA			"Cluster 31: Non-specific - Inflammatory response"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 7: Non-specific - Mitochondria"			"HPA039780: AB_10805594"	"unprognostic (1.13e-1)"	"unprognostic (4.03e-2)"	"unprognostic (2.78e-1)"	"unprognostic (1.92e-1)"	"unprognostic (3.31e-1)"	"unprognostic (1.34e-2)"	"unprognostic (2.65e-3)"	"unprognostic (1.49e-1)"	"unprognostic (8.96e-2)"	"unprognostic (5.79e-3)"	"unprognostic (6.30e-3)"	"unprognostic (1.99e-1)"	"unprognostic (3.08e-3)"	"unprognostic (4.91e-2)"	"unprognostic (4.08e-2)"	"unprognostic (1.58e-1)"	"unprognostic (3.41e-2)"	49.2	73.5	44.0	56.4	47.2	100.0	47.8	49.8	58.9	44.0	44.8	49.1	51.2	39.2	62.7	41.0	49.1	38.9	51.9	46.0	52.2	75.4	72.4	51.0	80.5	46.9	46.9	36.0	45.4	84.2	45.6	60.6	49.9	49.5	56.6	69.7	45.5	48.8	44.9	28.3	50.3	54.1	50.5	46.4	45.1	39.7	47.7	58.3	67.2	54.0	73.2	63.4	32.0	53.9	232.1	94.9	57.1	51.8	86.7	84.0	111.3	174.3	127.3	120.7	79.6	145.9	129.1	125.6	192.2	128.7	107.5	76.1	89.6	110.3	177.7	124.8	77.3	130.9	48.4	68.1	94.6	77.1	102.5	74.1	86.5	107.6	92.1	86.7	132.2	58.2	31.0	359.9	173.4	137.6	107.5	46.1	65.4	134.2	99.0	79.0	73.8	215.4	102.6	132.7	64.2	39.8	106.4	64.4	74.8	71.2	133.6	96.2	125.7	65.1	41.1	121.1	172.6	261.3	151.4	176.1	88.8	142.1	56.9	218.1	163.8	142.5	133.7	138.4	148.5	119.6	111.3	125.4	126.5	102.3	87.4	110.1	198.8	106.3	155.7	90.7	132.3	324.7	44.0	47.2	49.8	58.9	46.0	52.2	46.9	46.9	49.9	50.5	47.7	53.9	80.6	60.9	67.9	0.0	53.4	0.0	0.0	0.0	0.0	0.0	97.2	66.5	0.0	0.0	29.1	108.5	0.0	215.1	114.7	0.0	97.8	166.8	0.0	63.9	46.8	35.5	0.0	0.0	0.0	135.0	230.6	30.9	0.0	64.7	45.4	31.5	0.0	0.0	238.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	72.5	0.0	0.0	123.5	0.0	0.0	0.0	0.0	206.0	0.0	0.0	21.0	0.0	0.0	176.8	32.8	0.0	0.0	0.0	37.1	0.0	0.0	0.0	0.0	489.3	48.1	63.4	0.0	0.0
SMOX	"C20orf16, dJ779E11.1, FLJ20746, MGC1010, PAO, PAOh1, SMO"	ENSG00000088826	"Spermine oxidase"	Q9NWM0	20	4120980-4187747	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 61.3"	"Cell type enhanced"	"Detected in many"		"Ductal cells: 48.4;Erythroid cells: 89.7;Macrophages: 73.3;Pancreatic endocrine cells: 131.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	5	"classical monocyte: 1.0;myeloid DC: 2.4;neutrophil: 3.6;plasmacytoid DC: 1.1"	"Group enriched"	"Detected in many"	6	"dendritic cells: 2.4;granulocytes: 3.6;monocytes: 1.0"	"Cell line enhanced"	"Detected in many"		"A549: 119.6;Karpas-707: 201.7;RPTEC TERT1: 91.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA047117, HPA060198"	Approved		Supported	"Nucleoplasm,Nuclear membrane,Vesicles,Cytosol"		NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 22: Non-specific - Unknown function"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 51: Myeloid cells - Hemostasis"	Nucleoplasm	"Nuclear membrane, Vesicles, Cytosol"	"HPA047117: AB_2679940, HPA060198: AB_2684220"	"unprognostic (1.24e-2)"	"unprognostic (6.55e-2)"	"unprognostic (7.24e-3)"	"unprognostic (2.77e-1)"	"unprognostic (1.40e-1)"	"unprognostic (2.32e-1)"	"prognostic unfavorable (3.33e-6)"	"prognostic unfavorable (1.36e-4)"	"unprognostic (4.92e-2)"	"unprognostic (3.37e-1)"	"unprognostic (7.18e-2)"	"unprognostic (7.58e-2)"	"prognostic unfavorable (1.06e-4)"	"unprognostic (4.08e-2)"	"unprognostic (2.64e-3)"	"unprognostic (1.26e-2)"	"unprognostic (3.07e-1)"	8.5	4.4	50.9	4.4	61.3	32.2	5.3	54.5	60.9	17.7	32.8	5.6	10.6	10.8	7.1	8.5	7.4	15.1	6.8	46.3	51.7	20.5	8.5	4.9	4.8	56.6	54.4	12.5	32.5	25.2	13.2	6.2	53.7	12.2	1.2	2.9	12.1	7.9	4.3	11.9	8.1	4.0	53.0	6.4	20.1	5.8	55.5	4.3	6.8	2.8	2.6	8.2	12.4	54.1	11.0	119.6	8.3	6.3	5.5	8.2	14.6	15.6	29.8	11.1	7.4	49.5	29.6	0.0	5.1	14.4	18.0	21.6	6.8	7.5	4.8	0.0	3.5	21.5	4.1	50.6	35.0	4.1	8.3	31.3	13.1	23.1	9.8	13.4	19.8	16.7	4.8	201.7	6.7	3.3	8.1	12.1	10.2	10.7	16.3	7.3	10.3	29.1	91.4	8.3	1.6	7.2	28.9	3.4	54.1	4.2	0.3	5.1	24.0	12.7	12.0	2.3	12.2	9.1	1.7	0.1	10.6	5.4	9.8	0.0	1.0	0.2	0.0	0.4	0.0	0.1	0.2	0.2	2.4	0.0	0.0	0.0	3.6	0.3	0.1	1.1	0.0	16.0	50.9	61.3	54.5	60.9	46.3	51.7	56.6	54.4	53.7	53.0	55.5	54.1	4.4	0.0	0.5	38.5	3.8	12.6	12.0	14.4	6.8	0.5	6.9	4.6	1.7	12.8	6.3	11.0	0.0	0.4	0.2	1.4	0.0	48.4	4.0	9.2	15.8	11.2	6.0	89.7	1.6	30.5	0.8	11.3	6.6	18.7	5.7	10.4	13.6	2.3	20.6	0.0	3.5	3.0	6.1	3.1	10.2	7.7	14.6	73.3	8.8	5.6	22.6	25.4	1.0	9.0	6.2	131.3	1.5	13.5	7.4	13.1	4.0	3.8	1.2	1.4	0.0	2.7	10.2	19.1	7.8	2.1	10.5	0.3	2.1	1.9	3.7	12.6
SOD1	"ALS, ALS1, IPOA"	ENSG00000142168	"Superoxide dismutase 1"	P00441	21	31659666-31668931	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		"Antioxidant, Oxidoreductase"	"Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 1645.6"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 3357.9;Proximal tubular cells: 3285.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001401, CAB008670"	Enhanced		Supported	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA	44900000	50000000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 15: Liver - Metabolism"	"Cluster 16: U-266 - Nucleosome"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	"Nucleoplasm, Plasma membrane, Cytosol"		"CAB008670: AB_1623312, HPA001401: AB_1080132"	"unprognostic (1.73e-1)"	"unprognostic (1.18e-2)"	"unprognostic (4.43e-1)"	"unprognostic (6.19e-2)"	"unprognostic (1.39e-1)"	"unprognostic (9.59e-3)"	"unprognostic (8.34e-2)"	"unprognostic (2.30e-1)"	"unprognostic (3.47e-1)"	"unprognostic (5.28e-2)"	"unprognostic (9.33e-2)"	"unprognostic (1.96e-1)"	"unprognostic (1.03e-2)"	"unprognostic (1.66e-1)"	"unprognostic (1.74e-2)"	"unprognostic (1.57e-1)"	"unprognostic (3.26e-2)"	257.6	597.1	558.0	118.4	577.4	166.4	233.5	605.2	805.1	206.6	586.6	251.0	360.3	179.5	228.4	221.1	197.1	206.0	477.3	575.1	619.9	483.2	1645.6	153.9	169.6	619.8	604.6	302.1	117.1	210.6	236.7	155.8	653.1	203.9	180.5	248.6	160.5	204.2	428.0	152.1	266.7	136.6	588.1	147.5	210.4	132.1	585.8	165.7	197.4	355.9	151.7	232.1	220.6	634.7	526.8	451.4	309.2	312.8	407.3	282.1	257.8	430.2	258.0	291.3	217.4	593.6	326.0	628.2	441.2	405.8	517.7	186.1	453.3	320.6	239.9	463.3	540.0	1008.2	579.5	866.3	267.4	451.7	363.1	294.8	240.6	406.5	225.2	327.9	331.2	469.0	704.4	773.2	357.4	860.0	489.0	454.5	466.1	830.0	475.4	413.0	622.0	981.4	579.4	320.5	335.9	281.4	805.1	419.4	438.3	279.2	484.3	393.4	387.4	222.9	489.2	304.7	322.0	583.4	1374.2	741.8	455.7	654.3	301.9	204.2	159.7	194.0	313.4	234.0	365.3	427.1	509.2	402.4	212.8	310.1	521.8	412.1	37.8	241.4	465.4	240.6	746.0	474.5	558.0	577.4	605.2	805.1	575.1	619.9	619.8	604.6	653.1	588.1	585.8	634.7	319.8	294.9	175.1	38.2	248.1	491.4	672.7	479.2	319.8	226.6	264.1	352.9	721.0	527.6	294.7	391.8	47.9	703.4	250.2	703.5	1631.7	426.3	277.0	410.7	241.2	261.0	288.4	898.8	39.7	807.3	574.9	365.8	198.8	216.3	220.0	278.9	318.1	3357.9	363.3	282.7	45.5	402.7	366.2	220.0	318.5	952.2	521.9	224.2	419.8	29.0	313.1	598.5	239.0	28.6	68.7	322.8	600.9	528.1	178.2	567.0	1158.3	3285.9	638.3	216.5	440.4	313.6	404.5	211.7	506.3	379.9	349.8	725.9	423.1	470.3	593.6	497.7
SOD2	GClnc1	ENSG00000112096	"Superoxide dismutase 2"	P04179	6	159669069-159762529	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in all"	4	"bone marrow: 1083.7;skeletal muscle: 3230.1"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 2508.2;Prostatic glandular cells: 3524.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in all"	10	"neutrophil: 4470.5"	"Lineage enriched"	"Detected in all"	10	"granulocytes: 4470.5"	"Cell line enhanced"	"Detected in all"		"BJ hTERT+: 1611.9;GAMG: 614.3;HSkMC: 688.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001814, CAB002013"	Supported		Enhanced	Mitochondria		NA	NA		55000000	"Cluster 9: Neutrophils - Innate immune response"	"Cluster 59: Non-specific - Translation"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 41: Macrophages - Immune response"	Mitochondria		"CAB002013: , HPA001814: AB_1080134"	"unprognostic (2.47e-2)"	"unprognostic (2.77e-3)"	"unprognostic (1.14e-1)"	"unprognostic (1.57e-2)"	"unprognostic (1.31e-1)"	"unprognostic (1.69e-1)"	"unprognostic (1.49e-1)"	"unprognostic (3.10e-2)"	"unprognostic (1.37e-1)"	"unprognostic (6.67e-2)"	"unprognostic (2.76e-2)"	"unprognostic (7.14e-2)"	"prognostic unfavorable (1.72e-4)"	"unprognostic (8.12e-2)"	"unprognostic (4.14e-2)"	"unprognostic (5.99e-2)"	"unprognostic (1.82e-1)"	324.8	245.9	66.8	522.8	43.2	1083.7	169.0	37.8	125.8	92.6	99.7	126.4	60.5	105.4	7.2	136.5	118.5	121.8	178.5	37.0	101.0	252.4	459.8	266.5	64.8	250.0	96.1	55.8	212.3	69.1	42.7	62.9	192.9	130.8	37.9	25.1	328.8	43.9	3230.1	90.0	83.7	108.4	62.5	81.4	120.4	39.6	153.1	38.2	67.2	312.6	65.0	514.9	97.9	85.4	35.8	46.3	37.3	85.1	229.0	378.7	20.5	52.7	1611.9	57.7	131.1	91.3	19.4	70.7	144.5	54.1	614.3	58.9	39.1	42.5	42.4	71.2	87.2	74.5	71.8	152.3	169.5	74.0	31.9	688.9	68.5	180.9	133.6	40.7	30.0	44.9	106.7	82.2	55.4	37.6	60.3	46.6	63.3	41.5	55.4	79.6	50.3	63.9	106.2	56.6	71.5	29.5	105.1	52.4	21.4	14.1	33.1	33.7	30.4	168.6	62.1	92.5	87.9	37.8	100.2	86.5	186.7	57.4	23.6	146.3	364.4	181.1	38.8	273.9	43.4	43.4	54.9	38.5	105.2	38.3	45.0	36.9	4470.5	19.1	445.3	14.8	87.9	340.0	66.8	43.2	37.8	125.8	37.0	101.0	250.0	96.1	192.9	62.5	153.1	85.4	303.2	201.9	746.1	13.4	99.0	684.7	1144.9	2508.2	114.4	45.6	150.2	96.6	0.0	287.4	613.3	237.3	45.9	18.3	43.8	153.9	86.1	1400.2	318.2	281.7	649.8	593.0	79.6	101.2	31.1	1389.7	51.2	1098.4	103.5	1080.1	112.3	23.1	58.9	395.0	292.0	32.0	30.1	92.7	339.7	333.3	1425.8	111.5	58.1	1031.2	521.2	15.9	339.9	50.4	35.0	8.5	12.2	581.6	111.3	65.1	101.2	3524.0	128.6	530.1	269.6	61.8	39.5	1164.0	407.3	91.7	51.4	258.7	681.8	27.2	119.4	38.3	148.1	1195.7
SOD3	EC-SOD	ENSG00000109610	"Superoxide dismutase 3"	P08294	4	24789912-24800842	"Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins"		"Antioxidant, Heparin-binding, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"choroid plexus: 436.1"	"Cell type enhanced"	"Detected in many"		"Fibroblasts: 498.5;Leydig cells: 424.1;Peritubular cells: 365.6;Smooth muscle cells: 428.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"ASC diff: 66.2;BJ: 38.1;PC-3: 55.1;RPTEC TERT1: 231.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA042110	Supported				"Secreted to blood"	NA	NA	50400000	510000000		"Cluster 42: Ciliated cells - Cilium & Cell projection"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 50: Fibroblasts - ECM organization"			"HPA042110: AB_2677850"	"unprognostic (7.67e-2)"	"unprognostic (1.33e-1)"	"unprognostic (1.01e-1)"	"unprognostic (8.80e-2)"	"unprognostic (3.32e-2)"	"unprognostic (9.66e-2)"	"unprognostic (1.73e-1)"	"unprognostic (4.98e-2)"	"unprognostic (3.68e-1)"	"unprognostic (2.39e-1)"	"unprognostic (3.26e-2)"	"unprognostic (1.50e-1)"	"unprognostic (2.80e-2)"	"unprognostic (8.80e-2)"	"unprognostic (3.68e-2)"	"unprognostic (1.42e-1)"	"unprognostic (4.45e-2)"	221.4	20.4	14.3	26.1	20.9	0.0	134.2	15.8	23.8	226.5	436.1	122.7	18.2	151.6	10.4	62.1	177.6	22.4	150.1	47.1	14.1	124.1	16.5	155.0	10.6	22.9	23.4	59.7	86.7	2.6	19.8	39.8	17.5	131.3	13.4	1.9	70.9	23.4	22.0	91.9	65.2	37.1	16.4	24.8	102.1	74.1	19.0	5.8	176.6	22.9	7.0	178.3	170.4	13.6	0.0	0.0	0.0	0.0	66.2	17.3	2.0	38.1	16.7	2.3	1.4	0.5	0.0	0.0	11.8	8.0	0.1	0.2	0.0	0.0	0.7	0.1	0.0	0.0	0.0	0.9	0.2	0.0	0.0	16.8	0.0	15.8	0.0	17.9	0.1	0.0	1.1	0.0	0.0	0.1	0.3	1.1	8.0	0.0	55.1	0.0	0.0	0.6	231.3	0.8	0.2	0.2	0.0	1.2	0.0	2.1	32.8	0.0	0.0	8.7	1.0	1.6	0.4	0.1	0.0	0.0	8.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	14.3	20.9	15.8	23.8	47.1	14.1	22.9	23.4	17.5	16.4	19.0	13.6	46.1	12.8	18.1	7.2	1.0	90.8	65.5	0.6	10.2	0.4	21.7	22.1	23.0	144.4	7.6	90.1	0.0	211.4	1.8	25.6	15.6	63.6	18.7	81.9	45.8	21.0	34.6	0.0	0.1	1.8	17.0	498.5	5.1	80.3	0.0	0.1	15.4	0.2	17.3	0.0	0.1	51.9	0.0	0.3	115.5	33.9	424.1	3.2	80.0	3.7	0.0	20.7	0.0	0.5	0.7	3.5	89.3	365.6	1.1	80.4	0.0	142.7	0.1	1.4	197.2	6.5	428.9	73.2	4.4	6.1	70.3	190.0	7.6	6.1	51.8	9.6
SORD		ENSG00000140263	"Sorbitol dehydrogenase"	Q00796	15	45023147-45077185	"Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"cervix: 163.8;liver: 247.0"	"Cell type enhanced"	"Detected in many"		"Exocrine glandular cells: 138.7;Hepatocytes: 649.4;Prostatic glandular cells: 218.8;Proximal tubular cells: 270.2"	"Group enriched"	"Detected in all"	4	"liver cancer: 30.3;prostate cancer: 72.5;thyroid cancer: 30.6"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	10	"basophil: 86.3;eosinophil: 55.9"	"Lineage enriched"	"Detected in all"	12	"granulocytes: 86.3"	"Cell line enhanced"	"Detected in many"		"SK-BR-3: 57.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA040260, HPA040621"	Enhanced		Approved	Cytosol		NA	NA		2800000	"Cluster 52: Eosinophils - Transcription"	"Cluster 85: Liver - Metabolism"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Cytosol		"HPA040260: AB_10794872, HPA040621: AB_10795384"	"unprognostic (8.18e-2)"	"unprognostic (7.58e-2)"	"unprognostic (8.19e-2)"	"unprognostic (1.51e-1)"	"unprognostic (5.69e-3)"	"unprognostic (3.90e-2)"	"prognostic favorable (6.14e-5)"	"unprognostic (3.33e-3)"	"unprognostic (1.67e-1)"	"unprognostic (4.95e-2)"	"unprognostic (7.04e-3)"	"unprognostic (1.40e-1)"	"unprognostic (4.26e-2)"	"unprognostic (1.23e-2)"	"unprognostic (8.53e-2)"	"unprognostic (2.31e-2)"	"unprognostic (1.56e-1)"	2.0	15.7	4.9	3.1	3.8	2.8	53.8	7.4	8.4	163.8	1.9	5.3	7.5	4.3	6.9	10.2	6.7	8.2	5.6	5.0	4.5	50.3	247.0	3.2	2.6	4.3	3.7	2.4	5.7	4.4	3.1	2.5	4.0	87.9	7.8	4.8	5.3	27.0	2.2	16.6	7.2	3.5	4.2	2.3	9.2	12.2	3.9	3.7	89.4	2.8	3.4	9.1	6.9	6.3	12.3	12.2	4.7	20.8	4.4	5.3	5.9	1.8	3.5	12.2	7.0	12.2	5.8	2.7	8.0	5.4	4.1	17.6	19.9	19.1	9.2	29.9	12.3	13.5	12.1	50.3	0.2	18.0	25.5	6.7	18.0	6.6	9.5	5.4	12.5	15.1	11.7	10.6	14.9	8.1	18.4	38.3	39.0	29.4	13.8	0.9	16.6	6.4	16.8	12.1	25.1	12.2	2.1	57.3	5.9	5.2	16.4	22.5	4.7	3.5	38.0	1.6	5.8	8.7	4.5	4.4	14.2	18.6	10.6	86.3	1.7	55.9	1.6	1.5	1.7	5.4	1.3	1.6	1.7	6.9	1.6	1.4	3.8	1.1	2.1	2.4	2.5	2.0	4.9	3.8	7.4	8.4	5.0	4.5	4.3	3.7	4.0	4.2	3.9	6.3	3.9	0.0	3.1	5.5	11.9	7.8	26.5	14.8	17.6	10.8	24.7	17.5	3.2	25.8	28.1	33.1	0.0	1.3	2.3	15.0	29.4	68.2	31.7	40.2	17.4	4.9	84.8	37.5	4.8	138.7	5.1	7.5	31.1	43.7	8.8	11.5	15.7	649.4	16.0	3.3	5.4	32.5	22.4	24.2	6.4	24.1	3.7	12.2	16.0	1.0	13.3	9.0	2.1	7.1	8.9	89.0	18.1	6.0	7.9	218.8	8.0	270.2	42.5	4.7	0.0	8.9	8.9	7.4	2.8	35.1	20.3	1.0	6.5	15.3	39.4	131.2
SPR	SDR38C1	ENSG00000116096	"Sepiapterin reductase"	P35270	2	72887382-72892158	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, Dystonia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 85.3;Exocrine glandular cells: 81.1;Proximal tubular cells: 91.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	7	"classical monocyte: 8.3;intermediate monocyte: 2.4;myeloid DC: 8.9"	"Group enriched"	"Detected in many"	11	"dendritic cells: 8.9;monocytes: 8.3"	"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA039505	Uncertain		Supported	Nucleoplasm,Cytosol		NA	NA		180000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 22: Non-specific - Unknown function"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 1: Pancreatic cells - Digestion"	"Nucleoplasm, Cytosol"		"HPA039505: AB_10795466"	"unprognostic (4.09e-1)"	"unprognostic (1.22e-1)"	"unprognostic (7.72e-3)"	"unprognostic (1.97e-1)"	"unprognostic (2.46e-2)"	"unprognostic (1.06e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.47e-1)"	"unprognostic (1.12e-1)"	"unprognostic (9.79e-2)"	"unprognostic (1.62e-1)"	"unprognostic (1.37e-1)"	"unprognostic (1.80e-1)"	"unprognostic (7.50e-3)"	"unprognostic (2.87e-1)"	"unprognostic (1.43e-3)"	"unprognostic (1.95e-1)"	25.9	50.8	26.0	7.6	27.2	0.6	20.0	27.2	61.4	14.5	39.6	36.4	23.4	13.4	36.9	19.7	26.3	11.9	44.4	26.8	30.0	44.2	99.8	15.9	3.2	27.9	31.5	12.2	63.5	38.4	10.9	6.8	29.8	26.2	32.5	3.1	31.2	16.7	43.9	9.1	22.0	11.5	27.9	9.6	42.1	7.3	28.5	2.4	20.5	25.4	5.1	25.2	13.7	28.0	47.5	130.9	0.6	20.0	51.2	18.5	31.8	21.4	31.8	16.0	15.0	84.0	48.0	34.5	25.4	26.1	80.6	43.9	58.1	35.1	13.3	10.0	43.7	51.7	30.8	87.4	19.1	8.2	13.6	16.7	38.7	17.6	19.7	32.7	42.6	25.4	54.0	6.8	21.4	100.5	3.3	31.1	10.9	139.9	118.7	0.0	82.8	20.3	85.8	73.4	8.0	14.6	39.6	89.7	31.0	16.9	40.4	9.9	52.8	17.4	42.2	30.5	38.7	7.2	16.9	2.3	25.0	17.6	31.0	0.0	8.3	0.7	0.3	2.4	0.3	0.0	0.1	0.1	8.9	0.0	0.1	0.3	0.0	0.0	0.9	0.9	0.0	2.4	26.0	27.2	27.2	61.4	26.8	30.0	27.9	31.5	29.8	27.9	28.5	28.0	13.8	12.8	7.3	0.3	1.1	8.4	23.0	14.8	20.5	0.7	22.2	16.5	46.2	38.6	10.8	42.3	0.0	18.1	0.4	85.3	21.5	56.9	0.3	12.5	4.2	16.7	11.4	6.6	0.7	81.1	10.6	13.9	26.0	6.7	4.5	8.4	17.2	62.9	42.1	1.7	0.4	39.6	12.2	6.0	7.4	1.5	9.3	9.7	14.2	1.9	20.8	13.8	0.0	0.0	0.3	43.3	50.4	5.7	1.4	33.9	71.0	91.6	11.2	0.7	6.6	8.3	8.6	0.4	10.2	17.8	6.5	4.4	1.9	8.7	57.8	15.6
SQLE		ENSG00000104549	"Squalene epoxidase"	Q14534	8	124998497-125022283	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA018038, HPA020762"	Enhanced		Uncertain	Vesicles,Cytosol		NA	NA			"Cluster 23: Antigen presenting cells - Antigen presentation"	"Cluster 37: Intestine - Unknown function"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"	"Vesicles, Cytosol"		"HPA018038: AB_2669753, HPA020762: AB_2670512"	"unprognostic (1.37e-2)"	"unprognostic (6.26e-3)"	"unprognostic (5.12e-2)"	"unprognostic (9.51e-3)"	"unprognostic (4.63e-1)"	"prognostic unfavorable (7.42e-4)"	"unprognostic (4.76e-3)"	"prognostic unfavorable (4.67e-4)"	"unprognostic (3.45e-2)"	"unprognostic (7.21e-2)"	"prognostic unfavorable (2.73e-4)"	"unprognostic (7.51e-2)"	"prognostic unfavorable (5.70e-4)"	"unprognostic (9.71e-2)"	"unprognostic (4.62e-2)"	"unprognostic (1.19e-3)"	"unprognostic (7.74e-3)"	8.6	31.1	17.5	19.6	27.0	23.0	22.1	26.8	24.0	30.7	25.4	21.6	31.0	16.4	9.1	78.7	18.6	10.7	7.2	18.6	24.4	17.1	72.3	30.9	17.7	47.3	27.7	14.3	10.7	22.7	16.5	47.5	35.1	25.0	18.6	17.8	19.1	7.6	1.4	49.4	14.0	12.3	27.6	9.7	21.8	59.4	21.8	14.2	10.5	1.6	29.4	14.7	46.2	34.6	135.5	51.5	301.6	87.2	91.7	154.1	30.5	34.9	106.3	46.5	84.7	70.6	192.3	92.7	49.2	43.2	186.0	101.0	127.3	192.4	53.6	77.1	268.3	265.2	32.6	181.1	134.6	31.5	74.6	106.1	201.4	138.8	113.3	29.8	51.5	64.2	153.8	174.8	38.1	223.7	109.6	39.3	125.2	92.6	35.2	47.5	55.4	126.6	329.3	153.3	93.9	47.6	71.6	226.3	74.1	96.5	60.7	81.3	50.8	19.2	66.0	22.9	31.6	31.6	69.6	126.6	32.0	93.7	33.8	1.5	6.3	0.7	10.6	10.8	5.0	16.6	6.0	9.5	15.2	17.1	8.2	8.6	0.2	12.6	12.7	10.8	7.1	7.7	17.5	27.0	26.8	24.0	18.6	24.4	47.3	27.7	35.1	27.6	21.8	34.6	13.2	60.9	97.9	21.5	34.7	22.9	64.0	199.9	16.5	41.8	35.6	27.3	6.1	31.5	129.6	53.3	50.1	99.7	20.6	81.6	7.9	60.3	21.0	95.9	23.3	39.7	31.7	22.3	14.3	83.6	133.7	35.3	51.0	80.5	41.3	77.1	9.7	127.9	61.1	148.0	18.8	58.0	126.1	10.9	30.1	13.2	23.9	22.2	21.4	13.1	91.0	24.3	8.2	20.1	77.9	98.6	38.4	10.9	30.6	118.0	17.3	3.7	123.0	61.1	26.3	12.5	42.0	179.5	128.6	69.5	89.1	217.1	21.1	171.8	35.0	114.8
SQOR	"CGI-44, SQR, SQRDL"	ENSG00000137767	"Sulfide quinone oxidoreductase"	Q9Y6N5	15	45631148-45691281	"Enzymes, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"intestine: 210.0"	"Cell type enhanced"	"Detected in many"		"Ductal cells: 118.1;Exocrine glandular cells: 176.2;Hofbauer cells: 134.3;monocytes: 154.5;Pancreatic endocrine cells: 156.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"HBEC3-KT: 304.0"									"HPA017079, HPA041589"	Enhanced		Supported	Mitochondria		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 37: Intestine - Unknown function"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 7: Non-specific - Mitochondria"	Mitochondria		"HPA017079: AB_1857467, HPA041589: AB_2677565"	"unprognostic (6.15e-2)"	"unprognostic (3.28e-2)"	"unprognostic (2.15e-1)"	"prognostic favorable (2.57e-4)"	"unprognostic (2.75e-2)"	"unprognostic (5.51e-2)"	"unprognostic (6.68e-3)"	"prognostic unfavorable (8.80e-4)"	"unprognostic (1.81e-1)"	"unprognostic (3.77e-1)"	"unprognostic (6.65e-3)"	"unprognostic (2.37e-1)"	"unprognostic (3.14e-3)"	"unprognostic (2.29e-1)"	"unprognostic (4.92e-2)"	"unprognostic (7.44e-2)"	"unprognostic (4.38e-1)"	46.4	22.6	14.5	59.5	14.6	55.6	41.2	14.6	19.7	36.3	17.2	210.0	57.7	18.8	19.3	112.9	26.6	31.4	22.0	13.6	14.7	36.6	82.6	61.5	38.2	16.7	15.1	8.8	39.8	24.1	12.5	17.6	15.6	41.2	178.8	4.9	56.3	27.8	132.8	41.7	55.9	43.2	15.9	47.3	54.4	5.1	15.8	23.7	32.5	43.7	57.7	48.8	50.3	17.2	38.3	68.0	0.1	3.9	125.5	151.4	0.4	40.8	132.3	23.6	35.7	2.7	59.0	33.7	38.7	29.9	72.6	33.3	2.0	304.0	13.9	121.7	1.1	3.0	14.5	48.2	38.8	20.2	5.1	45.2	88.2	54.9	119.8	59.4	66.1	32.0	0.4	40.6	24.6	31.3	12.2	44.9	0.0	147.7	41.8	1.4	6.7	47.1	184.9	55.2	1.2	1.2	10.1	25.8	13.1	0.8	56.9	61.7	76.8	9.7	2.2	131.6	9.0	53.5	61.0	2.0	96.9	104.6	10.9	112.5	212.1	84.6	76.6	161.0	104.6	54.3	97.9	83.6	135.2	48.6	51.8	55.2	302.5	53.4	152.4	40.5	149.0	169.6	14.5	14.6	14.6	19.7	13.6	14.7	16.7	15.1	15.6	15.9	15.8	17.2	24.4	32.1	64.1	0.0	5.8	0.0	0.0	0.0	0.0	0.0	31.4	14.7	0.0	0.0	14.9	14.7	0.0	0.7	19.8	0.0	11.7	118.1	0.0	15.9	7.0	13.9	0.0	0.0	0.0	176.2	0.9	11.3	0.0	37.6	11.4	1.3	0.0	0.0	134.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	54.3	0.0	0.0	154.5	0.0	0.0	0.0	0.0	156.2	0.0	0.0	3.3	0.0	0.0	45.8	24.0	0.0	0.0	0.0	6.9	0.0	0.0	0.0	0.0	0.8	13.5	1.6	0.0	0.0
SRD5A1		ENSG00000145545	"Steroid 5 alpha-reductase 1"	P18405	5	6633427-6674386	"Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins"	"Differentiation, Sexual differentiation"	Oxidoreductase	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 29.0"	"Cell type enhanced"	"Detected in many"		"Basal squamous epithelial cells: 67.2;Hepatocytes: 103.4;Ionocytes: 52.9;Squamous epithelial cells: 139.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"basophil: 3.5"	"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA051402	Approved					NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 15: Liver - Metabolism"	"Cluster 20: HeLa - Mitochondria"	"Cluster 61: Squamous epithelial cells - Keratinization"			"HPA051402: AB_2681470"	"unprognostic (1.40e-2)"	"unprognostic (1.33e-2)"	"unprognostic (2.30e-3)"	"prognostic unfavorable (8.73e-6)"	"unprognostic (9.38e-3)"	"unprognostic (8.90e-2)"	"unprognostic (3.78e-2)"	"unprognostic (5.90e-2)"	"unprognostic (3.83e-1)"	"unprognostic (1.42e-1)"	"unprognostic (7.70e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.56e-3)"	"unprognostic (3.01e-1)"	"unprognostic (2.24e-1)"	"unprognostic (1.59e-1)"	"unprognostic (5.47e-2)"	1.5	2.0	4.7	1.9	5.3	2.2	11.0	7.4	8.8	3.9	0.1	2.4	4.1	1.7	3.0	11.0	1.7	1.7	1.0	5.5	3.2	4.6	29.0	1.9	2.3	6.0	3.3	2.5	2.3	1.4	1.1	1.0	6.3	1.5	2.3	3.8	2.7	1.1	1.3	13.6	4.1	1.6	1.8	1.4	2.5	1.5	6.9	1.6	1.3	0.7	4.1	1.1	6.6	8.3	5.2	6.1	8.0	6.7	7.6	7.3	3.5	5.7	4.5	5.7	3.5	6.0	5.3	7.1	8.1	8.7	9.1	9.8	6.6	4.0	6.0	4.3	2.6	2.2	15.3	3.7	3.4	3.3	1.8	5.4	11.3	4.1	3.2	4.2	2.9	2.7	3.7	6.2	7.5	7.1	1.4	3.6	4.5	4.1	4.7	5.1	5.8	2.0	7.6	5.4	14.0	6.4	18.2	7.6	5.8	6.1	2.6	0.9	5.8	8.6	3.4	14.2	7.6	2.3	3.6	2.6	7.2	3.6	8.0	3.5	1.3	0.5	0.3	1.0	0.2	0.5	0.3	0.5	1.6	0.6	0.2	0.3	0.7	0.5	1.1	0.7	0.4	0.5	4.7	5.3	7.4	8.8	5.5	3.2	6.0	3.3	6.3	1.8	6.9	8.3	3.7	3.2	2.7	7.8	11.9	18.5	6.7	19.0	67.2	5.0	14.5	9.1	2.6	11.5	12.8	5.5	4.2	0.9	5.0	8.3	7.9	9.8	8.1	2.6	4.3	3.2	2.4	4.4	15.5	4.7	7.4	4.7	16.3	3.2	1.3	6.0	4.6	103.4	13.0	6.7	14.9	7.2	52.9	19.4	11.6	2.6	3.4	11.6	7.2	6.5	50.7	5.1	10.3	9.0	7.6	6.7	10.4	7.9	7.2	9.4	24.9	23.4	10.4	3.8	0.0	3.7	6.1	3.4	4.4	139.2	30.4	0.8	5.9	5.2	12.0	10.2
SRD5A2		ENSG00000277893	"Steroid 5 alpha-reductase 2"	P31213	2	31522480-31580938	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters"	"Differentiation, Sexual differentiation"	Oxidoreductase	"Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	15	"epididymis: 23.5;fallopian tube: 20.4;liver: 60.8;prostate: 16.8;seminal vesicle: 18.0"	"Group enriched"	"Detected in some"	5	"Early spermatids: 71.7;Endometrial ciliated cells: 29.6;Hepatocytes: 20.0;Late spermatids: 59.9"	"Group enriched"	"Detected in some"	6	"endometrial cancer: 1.1;liver cancer: 4.2;prostate cancer: 3.2"	"Region enriched"	"Detected in single"	11	"midbrain: 1.0"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"RT4: 1.5"	"Not detected"	"Not detected"			"Not detected"	"Not detected"									NA	NA				"Cluster 85: Liver - Metabolism"	"Cluster 15: RT4 - Unknown function"	"Cluster 34: Spermatids - Unknown function"				"unprognostic (6.75e-3)"	"unprognostic (2.00e-2)"	"unprognostic (1.66e-1)"	"unprognostic (1.08e-3)"	"unprognostic (5.92e-3)"	"unprognostic (3.37e-2)"	"unprognostic (2.79e-3)"	"unprognostic (6.56e-2)"	"unprognostic (9.10e-2)"	"unprognostic (1.39e-2)"	"unprognostic (3.06e-2)"	"unprognostic (9.79e-3)"	"unprognostic (6.61e-6)"	"unprognostic (4.37e-2)"	"unprognostic (2.04e-1)"	"unprognostic (3.85e-1)"	"unprognostic (3.48e-3)"	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.2	23.5	0.0	20.4	0.0	0.0	0.0	0.0	0.3	60.8	0.7	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	16.8	0.0	0.1	0.0	18.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	1.4	0.0	0.2	0.0	0.0	0.0	1.6	1.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.6	0.1	0.0	6.2	0.0	0.0	0.0	0.0	0.0	0.6	2.8	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	71.7	29.6	0.2	0.2	0.0	0.0	0.9	0.0	0.0	1.9	0.0	0.5	0.0	0.0	0.4	20.0	0.0	0.0	1.0	0.0	0.0	0.3	0.0	59.9	0.6	0.1	0.0	3.7	0.0	0.0	0.0	0.5	0.9	0.1	0.0	1.2	0.0	0.7	0.0	0.3	7.3	0.0	0.0	0.0	0.2	1.2	0.8	0.0	0.0	0.0	0.1	0.0	0.0	8.6
SRD5A3	"FLJ13352, SRD5A2L, SRD5A2L1"	ENSG00000128039	"Steroid 5 alpha-reductase 3"	Q9H8P0	4	55346213-55373100	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"		Oxidoreductase	"Cataract, Congenital disorder of glycosylation, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 245.5;Club cells: 245.2;Pancreatic endocrine cells: 155.5;Respiratory ciliated cells: 195.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-BR-3: 79.6"					"Low region specificity"	"Detected in all"			HPA027006	Uncertain		Approved	"Plasma membrane,Cytosol"		NA	NA			"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"	"Plasma membrane, Cytosol"		"HPA027006: AB_1857469"	"unprognostic (1.12e-2)"	"unprognostic (1.01e-1)"	"unprognostic (4.02e-2)"	"prognostic favorable (9.39e-4)"	"unprognostic (1.50e-2)"	"unprognostic (4.81e-2)"	"prognostic unfavorable (1.80e-6)"	"unprognostic (9.31e-2)"	"unprognostic (5.28e-2)"	"unprognostic (1.81e-2)"	"unprognostic (3.29e-3)"	"unprognostic (1.18e-1)"	"prognostic unfavorable (4.85e-10)"	"unprognostic (4.16e-2)"	"unprognostic (1.42e-1)"	"unprognostic (1.43e-2)"	"unprognostic (9.52e-2)"	12.5	12.0	10.4	2.5	11.5	3.7	12.2	11.0	12.4	12.9	9.2	7.3	3.8	6.8	4.2	26.1	5.6	10.3	9.3	10.7	10.1	9.6	14.5	10.5	2.5	11.0	11.2	3.1	20.2	7.0	5.9	4.0	10.8	7.4	4.1	1.5	16.4	2.9	6.3	15.4	7.0	2.6	10.9	6.8	9.7	3.3	10.9	6.0	7.6	5.4	6.0	10.0	14.7	12.7	9.7	4.3	10.3	10.1	29.4	20.4	5.6	10.4	9.3	2.4	5.4	6.5	19.5	21.2	11.7	11.0	11.1	7.0	5.3	7.9	3.9	6.6	17.1	12.3	5.2	15.8	9.2	23.7	6.1	17.6	14.5	5.4	5.3	7.8	14.4	38.5	21.2	47.7	21.1	10.8	36.0	10.3	13.0	53.2	9.3	11.4	3.3	14.0	12.8	7.9	16.0	9.1	10.7	79.6	8.3	9.0	9.4	17.9	8.3	25.0	4.7	2.0	8.1	28.6	15.8	7.9	34.1	29.5	25.9	25.6	35.8	11.7	16.1	56.5	18.6	12.5	12.0	15.2	30.2	12.7	10.2	14.4	1.8	8.6	59.5	61.7	12.5	23.1	10.4	11.5	11.0	12.4	10.7	10.1	11.0	11.2	10.8	10.9	10.9	12.7	25.4	9.6	15.9	4.6	7.8	13.6	13.3	245.5	5.2	4.9	43.8	29.3	5.3	34.3	245.2	5.5	4.2	27.0	21.2	12.2	3.9	93.4	3.2	51.2	31.0	19.6	12.0	14.9	11.1	105.4	106.0	16.2	13.3	105.9	14.0	6.7	17.5	18.6	63.4	10.1	17.1	22.6	57.0	32.4	34.1	0.5	1.8	27.6	24.9	4.7	31.3	21.9	18.6	8.5	23.4	155.5	10.0	5.7	16.8	17.5	9.4	18.4	195.0	3.9	13.1	13.3	28.2	3.5	20.1	32.7	29.7	7.5	7.2	15.4	23.3	108.6
SRXN1	"C20orf139, dJ850E9.2, Npn3, SRX1, YKL086W"	ENSG00000271303	"Sulfiredoxin 1"	Q9BYN0	20	646615-653200	"Enzymes, Predicted intracellular proteins"		"Antioxidant, Oxidoreductase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"Ductal cells: 4.4;Erythroid cells: 4.8;Excitatory neurons: 4.5;Exocrine glandular cells: 6.8;Inhibitory neurons: 5.8;Pancreatic endocrine cells: 6.5;Squamous epithelial cells: 9.7"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in many"	4	"neutrophil: 12.3"	"Lineage enriched"	"Detected in many"	5	"granulocytes: 12.3"	"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 59: Non-specific - Transcription"				"unprognostic (7.31e-3)"	"unprognostic (6.08e-3)"	"unprognostic (2.50e-1)"	"unprognostic (5.49e-2)"	"unprognostic (1.70e-2)"	"unprognostic (1.18e-3)"	"prognostic unfavorable (6.22e-5)"	"unprognostic (1.37e-3)"	"unprognostic (1.69e-1)"	"unprognostic (1.58e-2)"	"unprognostic (5.26e-2)"	"unprognostic (2.48e-1)"	"unprognostic (7.71e-2)"	"unprognostic (1.79e-2)"	"unprognostic (7.57e-2)"	"unprognostic (1.57e-2)"	"unprognostic (1.52e-3)"	20.8	62.7	24.7	10.3	25.1	24.0	12.4	26.7	29.1	18.4	21.8	16.6	18.0	16.5	15.0	63.0	15.3	16.2	37.3	24.1	32.2	23.3	36.7	21.2	5.7	29.2	30.3	16.6	16.0	32.7	22.2	14.0	29.2	15.7	15.1	20.0	18.2	18.3	45.6	11.5	16.7	19.2	25.1	14.5	32.1	8.5	30.5	4.6	26.9	21.7	10.5	26.1	22.7	22.8	119.4	201.0	13.2	26.3	54.5	60.3	30.0	83.6	64.9	58.4	34.2	69.4	63.5	21.8	52.3	133.8	260.2	58.5	50.3	132.9	56.0	23.2	28.2	86.6	43.8	221.7	73.4	37.4	51.4	38.7	121.5	79.3	76.5	47.9	64.3	32.5	76.5	88.5	64.8	35.4	0.2	20.5	26.6	183.8	73.8	0.4	18.1	45.7	41.0	42.3	16.8	32.2	65.5	144.5	98.8	35.8	49.3	23.0	66.0	80.9	56.5	73.5	119.6	23.1	63.7	17.3	51.5	18.0	67.8	2.4	2.0	3.0	2.0	1.8	1.4	0.4	1.0	2.5	1.0	0.0	0.0	0.7	12.3	0.5	2.2	0.1	1.1	0.4	24.7	25.1	26.7	29.1	24.1	32.2	29.2	30.3	29.2	25.1	30.5	22.8	0.2	0.0	0.0	3.3	0.3	0.1	0.1	0.2	1.8	0.7	0.4	0.1	0.3	0.0	0.0	0.0	0.0	0.2	0.2	2.9	0.0	4.4	0.0	0.2	0.5	0.6	1.2	4.8	4.5	6.8	0.3	0.8	1.5	0.3	0.0	0.1	0.0	0.4	1.0	0.0	5.8	1.4	0.0	0.0	0.3	0.1	0.0	1.3	0.0	3.7	2.1	0.2	0.0	1.0	0.9	6.5	0.8	0.4	2.4	0.3	2.8	0.2	0.1	0.3	0.0	0.1	1.6	0.0	0.0	9.7	0.0	0.0	0.9	0.1	2.0	0.0
STEAP4	"FLJ23153, SchLAH, STAMP2, TIARP, TNFAIP9"	ENSG00000127954	"STEAP4 metalloreductase"	Q687X5	7	88270892-88306894	"Enzymes, Predicted membrane proteins, Transporters"	"Electron transport, Ion transport, Iron transport, Transport"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adipose tissue: 113.7"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 402.5;Club cells: 152.8;Sertoli cells: 460.2;Smooth muscle cells: 255.3"	"Cancer enhanced"	"Detected in many"		"prostate cancer: 45.9"	"Low region specificity"	"Detected in many"			"Immune cell enriched"	"Detected in some"	12	"neutrophil: 163.6"	"Lineage enriched"	"Detected in many"	12	"granulocytes: 163.6"	"Group enriched"	"Detected in some"	6	"HSkMC: 122.1;SiHa: 119.7;U-2197: 166.4"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA065201			Approved	"Nucleoplasm,Plasma membrane"		NA	NA			"Cluster 50: Neutrophils - Cellular senescence"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 18: U-2197 - ECM organization"	"Cluster 48: Smooth muscle cells - ECM organization"	"Nucleoplasm, Plasma membrane"		"HPA065201: "	"unprognostic (3.76e-2)"	"unprognostic (2.16e-2)"	"unprognostic (8.82e-2)"	"unprognostic (1.43e-1)"	"unprognostic (1.62e-1)"	"unprognostic (9.96e-2)"	"prognostic favorable (2.97e-4)"	"unprognostic (7.40e-2)"	"unprognostic (3.12e-1)"	"unprognostic (4.66e-2)"	"unprognostic (4.21e-1)"	"unprognostic (2.98e-1)"	"unprognostic (7.51e-3)"	"prognostic unfavorable (5.77e-4)"	"unprognostic (1.72e-1)"	"unprognostic (2.00e-1)"	"unprognostic (4.53e-2)"	113.7	46.3	1.0	31.7	0.9	7.1	68.6	2.8	1.5	21.3	17.0	13.3	3.8	17.9	7.8	15.4	36.1	22.7	24.1	1.4	1.0	11.8	24.3	67.5	7.2	1.2	0.9	4.4	10.6	16.0	13.0	15.3	0.8	60.0	9.2	1.9	26.8	10.6	13.4	19.3	10.6	29.3	0.4	5.4	10.6	13.4	1.1	7.8	53.1	16.6	5.1	34.3	22.7	1.1	4.9	0.0	0.1	0.1	0.1	1.9	0.3	0.0	0.3	0.0	0.1	0.1	23.6	0.1	0.1	0.0	0.4	18.7	0.1	0.0	0.1	0.0	0.1	0.1	7.9	0.1	0.1	0.1	0.2	122.1	0.1	0.4	0.9	0.0	0.0	0.1	0.3	0.4	0.0	3.0	0.1	0.5	0.1	1.0	0.0	0.2	0.1	0.3	0.0	0.3	0.2	0.2	119.7	9.9	0.0	0.1	0.8	0.0	0.1	0.4	0.3	166.4	0.1	0.1	0.1	0.1	0.2	0.9	0.2	0.4	13.5	1.4	0.0	0.8	0.0	0.0	0.0	0.0	1.0	0.1	0.0	0.0	163.6	0.2	0.1	0.3	0.0	3.2	1.0	0.9	2.8	1.5	1.4	1.0	1.2	0.9	0.8	0.4	1.1	1.1	77.2	54.5	402.5	0.0	0.8	9.4	5.8	8.6	1.8	1.8	21.6	8.3	9.1	0.0	152.8	0.0	2.1	0.4	1.1	0.4	0.0	14.6	23.8	14.6	20.5	14.7	0.0	0.0	0.5	9.6	10.6	39.8	1.1	51.2	16.4	0.0	15.4	0.7	2.8	0.0	0.8	0.2	16.2	7.2	7.4	10.9	114.9	12.2	5.4	6.5	19.0	2.7	0.0	1.0	0.1	18.6	0.0	9.1	0.2	49.3	0.1	0.1	72.8	0.3	460.2	9.6	255.3	0.9	0.3	1.5	18.8	10.9	3.1	57.7	0.2	16.6
SUMF1	"FGE, UNQ3037"	ENSG00000144455	"Sulfatase modifying factor 1"	Q8NBK3	3	3700814-4467273	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy, Mucopolysaccharidosis"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Oligodendrocytes: 85.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"ASC diff: 116.4;hTERT-RPE1: 117.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA038025	Uncertain				"Intracellular and membrane"	NA	NA		2800000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 1: Thyroid gland - Transcription"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 4: Macrophages - Innate immune response"			"HPA038025: AB_10675624"	"unprognostic (5.02e-2)"	"unprognostic (2.30e-1)"	"unprognostic (1.08e-1)"	"unprognostic (8.99e-3)"	"unprognostic (5.66e-2)"	"unprognostic (1.11e-1)"	"unprognostic (8.34e-3)"	"unprognostic (3.21e-1)"	"unprognostic (1.31e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.65e-2)"	"unprognostic (2.28e-1)"	"prognostic favorable (4.79e-7)"	"unprognostic (5.12e-2)"	"unprognostic (2.58e-1)"	"unprognostic (1.45e-1)"	"unprognostic (7.86e-2)"	20.7	19.5	10.4	13.1	12.0	10.2	29.2	10.9	12.2	21.3	15.6	23.9	13.3	15.8	26.8	28.7	25.6	19.7	12.5	10.2	12.2	39.3	27.4	23.0	12.6	12.2	11.7	17.4	18.9	46.8	14.5	18.8	11.4	22.1	29.6	3.4	22.8	17.7	4.3	20.3	14.1	20.5	11.4	16.8	23.8	5.1	13.1	10.6	28.4	7.6	13.4	20.0	18.5	13.1	25.0	20.6	11.4	6.3	116.4	61.3	21.9	34.4	53.9	16.2	18.2	9.6	78.9	3.7	20.3	63.0	24.3	13.3	5.0	39.0	25.2	12.0	10.1	5.4	18.9	26.2	30.0	6.1	14.4	56.6	43.2	18.2	5.3	117.9	44.8	8.9	9.1	8.4	45.8	40.2	3.4	9.1	12.0	22.8	23.4	6.3	17.0	16.0	86.6	28.0	2.2	12.6	24.6	56.8	20.4	19.5	75.7	15.6	41.4	32.5	4.2	25.3	21.0	10.4	22.8	1.7	63.2	13.5	24.7	66.1	100.5	35.6	38.9	81.8	35.2	26.6	31.2	32.9	86.6	30.7	39.4	32.0	36.2	42.0	78.2	45.9	16.9	90.2	10.4	12.0	10.9	12.2	10.2	12.2	12.2	11.7	11.4	11.4	13.1	13.1	12.8	19.2	20.1	36.9	13.8	12.7	18.8	32.9	21.1	5.6	29.5	23.2	5.5	18.6	16.7	38.6	6.2	29.8	9.7	16.5	11.7	39.3	26.1	14.2	14.1	13.7	8.4	11.1	53.2	19.1	23.3	25.8	21.4	21.9	17.1	10.4	17.5	18.7	28.2	3.3	57.0	19.7	4.1	37.1	12.0	10.7	16.4	24.3	19.6	62.8	43.9	6.8	11.3	56.8	85.5	14.0	16.4	17.3	11.5	13.7	10.5	23.8	19.4	6.2	6.6	21.2	16.5	4.8	5.1	25.9	11.8	24.4	11.6	11.1	25.6	18.3
SUOX		ENSG00000139531	"Sulfite oxidase"	P51687	12	55997180-56006641	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, Epilepsy, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Hepatocytes: 49.6;Proximal tubular cells: 35.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"T-47d: 72.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA038208, HPA038209"	Approved					NA	NA		44000	"Cluster 52: Eosinophils - Transcription"	"Cluster 1: Thyroid gland - Transcription"	"Cluster 6: T47d - Mammary gland"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA038208: AB_2675892, HPA038209: AB_10672738"	"unprognostic (1.72e-1)"	"unprognostic (7.40e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.25e-2)"	"unprognostic (1.86e-1)"	"unprognostic (9.72e-3)"	"unprognostic (1.71e-3)"	"unprognostic (2.86e-3)"	"unprognostic (3.27e-2)"	"unprognostic (9.74e-2)"	"prognostic favorable (6.28e-4)"	"unprognostic (6.95e-2)"	"prognostic favorable (4.77e-7)"	"unprognostic (1.65e-1)"	"unprognostic (1.89e-1)"	"unprognostic (2.85e-2)"	"prognostic favorable (8.32e-5)"	19.2	35.2	19.3	9.5	20.2	12.8	18.2	21.0	22.6	16.7	22.2	20.6	19.3	17.6	33.0	21.5	22.9	16.7	29.4	19.6	19.9	40.8	72.3	15.6	8.3	20.7	20.0	22.1	17.4	48.6	16.6	11.5	20.6	25.2	17.1	13.8	20.2	24.5	45.6	10.4	15.6	17.4	20.1	13.6	21.3	8.3	21.7	6.7	18.2	28.8	12.0	21.2	14.3	24.0	10.2	29.8	18.5	30.2	29.6	12.2	40.1	11.5	12.5	15.4	11.1	28.8	22.1	1.2	19.8	14.0	10.6	13.2	13.7	14.5	8.2	45.8	9.0	15.7	19.4	34.9	10.9	0.2	25.9	19.0	5.5	13.1	6.8	23.0	38.9	1.6	28.2	19.0	16.2	25.1	0.4	10.0	9.9	15.6	21.4	13.6	7.7	22.4	17.8	20.4	9.2	12.3	21.1	42.6	17.4	17.2	72.2	14.9	20.6	8.5	10.4	10.8	8.2	22.0	21.3	1.6	13.7	10.2	12.7	11.1	12.6	29.6	0.2	18.7	0.1	2.5	1.2	0.0	16.1	0.3	0.9	0.2	5.1	16.5	16.2	0.5	7.9	11.8	19.3	20.2	21.0	22.6	19.6	19.9	20.7	20.0	20.6	20.1	21.7	24.0	4.5	9.6	10.9	10.7	1.1	1.3	3.8	6.7	6.2	5.1	9.1	6.1	21.7	11.5	12.8	14.7	6.2	29.7	0.9	7.7	17.6	5.6	0.7	7.7	6.7	7.1	6.0	6.5	4.1	6.3	19.1	6.4	6.6	12.4	4.5	6.6	8.9	49.6	10.5	10.1	4.4	6.0	4.1	8.9	4.0	0.9	4.4	4.3	1.8	5.6	10.0	8.5	2.1	5.5	6.2	5.3	7.4	9.1	3.2	3.1	7.9	35.8	6.1	8.4	6.6	8.4	5.4	2.4	1.4	6.8	2.3	30.8	1.6	6.7	7.7	3.0
TDO2	"TDO, TPH2"	ENSG00000151790	"Tryptophan 2,3-dioxygenase"	P48775	4	155854738-155920406	"Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Tryptophan catabolism"	"Dioxygenase, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	47	"liver: 797.8"	"Cell type enriched"	"Detected in some"	7	"Hepatocytes: 1174.2"	"Cancer enriched"	"Detected in many"	18	"liver cancer: 35.7"	"Low region specificity"	"Detected in some"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	4	"EFO-21: 9.6;HDLM-2: 22.0;U-87 MG: 11.3"	"Group enriched"	"Detected in some"	7	"cerebellum: 6.3;hippocampal formation: 5.3;white matter: 1.9"	"Low region specificity"	"Detected in all"			HPA039611	Uncertain		Uncertain	"Plasma membrane,Cytosol"		NA	NA				"Cluster 60: Liver - Hemostasis & Lipid metabolism"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 2: Hepatocytes - Metabolism"	"Plasma membrane, Cytosol"		"HPA039611: "	"unprognostic (1.10e-1)"	"unprognostic (3.00e-3)"	"unprognostic (3.84e-2)"	"unprognostic (1.95e-1)"	"unprognostic (7.06e-2)"	"unprognostic (3.50e-1)"	"unprognostic (1.18e-1)"	"unprognostic (1.03e-1)"	"unprognostic (1.00e-1)"	"unprognostic (2.13e-2)"	"unprognostic (1.42e-1)"	"unprognostic (1.01e-1)"	"unprognostic (4.68e-8)"	"unprognostic (7.99e-2)"	"unprognostic (9.29e-3)"	"unprognostic (1.28e-1)"	"unprognostic (1.95e-2)"	0.3	1.6	0.3	16.8	0.5	0.0	0.1	0.2	1.2	0.2	0.2	1.2	3.5	0.4	0.6	0.7	0.3	1.9	0.0	0.5	0.3	0.6	797.8	3.2	3.1	0.2	1.1	0.1	0.3	0.1	4.0	0.6	0.2	0.2	1.4	0.0	0.4	0.2	0.2	0.0	5.9	2.5	0.3	1.9	1.6	0.4	0.3	0.2	0.2	0.0	2.6	7.6	0.1	0.7	0.0	1.9	0.0	0.0	0.1	0.0	0.0	0.0	1.6	0.0	0.0	0.1	0.0	0.0	9.6	0.0	0.2	0.0	0.1	0.0	0.0	22.0	0.0	0.1	0.0	0.0	0.3	0.3	0.0	1.1	0.0	0.0	0.0	0.9	0.0	0.0	0.1	3.5	0.3	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.2	1.6	0.0	0.3	0.0	0.0	0.1	0.5	0.0	0.0	0.0	0.2	0.0	1.2	0.4	0.5	0.0	3.4	0.0	0.0	11.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.5	0.2	1.2	0.5	0.3	0.2	1.1	0.2	0.3	0.3	0.7	0.8	0.0	0.0	0.7	2.7	0.0	0.1	0.0	0.0	0.0	0.1	0.3	0.6	158.7	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.9	0.5	0.1	1.1	2.4	0.0	32.0	4.1	0.0	0.0	1.7	3.6	0.1	0.0	0.0	29.6	1174.2	0.9	0.0	0.4	0.0	0.0	31.7	0.0	0.3	0.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	6.6	0.0	11.3	0.4	1.1	0.0	0.0	0.3	2.3	0.3	0.0	0.1
TECR	"GPSN2, MRT14, SC2, TER"	ENSG00000099797	"Trans-2,3-enoyl-CoA reductase"	Q9NZ01	19	14517085-14565980	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism"	Oxidoreductase	"Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Late spermatids: 1013.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA029780, HPA056488"	Supported		Supported	"Endoplasmic reticulum"		NA	NA		10000	"Cluster 20: T-cells - T-cell receptor"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 21: OE19 - Mitochondria"	"Cluster 10: Non-specific - Unknown function"	"Endoplasmic reticulum"		"HPA029780: AB_10603348, HPA056488: AB_2683149"	"unprognostic (9.73e-2)"	"unprognostic (3.69e-3)"	"unprognostic (1.55e-1)"	"unprognostic (8.08e-3)"	"unprognostic (1.20e-1)"	"unprognostic (3.96e-2)"	"unprognostic (3.68e-2)"	"unprognostic (1.24e-1)"	"unprognostic (1.36e-1)"	"unprognostic (9.16e-2)"	"unprognostic (1.29e-1)"	"unprognostic (5.05e-2)"	"unprognostic (3.65e-3)"	"unprognostic (2.53e-3)"	"unprognostic (2.34e-1)"	"unprognostic (2.07e-2)"	"prognostic unfavorable (2.60e-4)"	102.7	162.6	189.0	43.1	201.7	74.2	100.4	220.8	237.5	156.8	216.5	78.5	106.1	53.2	103.2	373.2	87.1	49.7	78.4	180.1	200.0	112.2	133.9	67.8	55.7	209.6	191.2	80.9	105.5	306.1	78.7	68.0	212.2	85.7	59.3	82.8	222.3	83.5	366.3	263.5	95.9	36.7	207.6	75.4	81.7	182.7	199.9	65.8	92.7	209.6	85.3	51.6	185.9	230.2	220.5	162.1	149.5	169.6	214.7	97.2	156.9	62.8	175.2	196.3	242.9	225.3	246.2	113.8	127.4	134.2	152.4	328.8	158.1	254.3	84.0	192.3	165.9	193.7	225.4	254.6	129.7	139.5	143.7	144.9	201.8	174.3	96.1	98.4	93.7	169.2	128.9	391.5	104.0	289.3	170.1	248.3	155.6	556.1	227.6	154.4	96.1	521.1	275.1	115.8	183.2	113.0	103.1	278.4	139.6	77.2	151.3	274.4	55.2	160.5	66.8	141.0	212.6	118.4	119.8	122.7	163.8	212.6	162.2	55.6	72.7	52.5	137.8	106.4	148.8	100.1	180.1	159.1	124.2	99.1	207.1	164.5	32.7	183.7	83.9	137.1	290.1	170.9	189.0	201.7	220.8	237.5	180.1	200.0	209.6	191.2	212.2	207.6	199.9	230.2	60.4	73.7	71.1	47.7	87.6	169.5	227.5	297.9	125.7	90.8	161.1	155.6	52.9	120.1	221.5	165.5	123.0	509.5	88.1	159.2	56.7	166.2	443.9	102.2	40.1	64.7	100.0	80.1	15.3	225.1	525.5	81.8	89.7	64.2	36.1	90.1	73.2	143.1	188.0	112.7	19.2	144.0	199.4	113.8	99.3	1013.1	72.7	77.8	163.7	18.7	61.6	577.9	103.0	12.5	46.5	104.8	128.2	60.2	206.1	110.2	343.2	202.9	213.1	177.5	65.7	68.4	286.7	215.0	134.2	255.3	239.7	486.2	117.7	116.0	216.2	196.5
TET1	"bA119F7.1, CXXC6, KIAA1676, LCX"	ENSG00000138336	"Tet methylcytosine dioxygenase 1"	Q8NFU7	10	68560337-68694487	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"brain: 4.9"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 54.5;Extravillous trophoblasts: 79.9;Oligodendrocyte precursor cells: 44.7;Oligodendrocytes: 45.3;Theca cells: 43.7"	"Cancer enriched"	"Detected in some"	15	"testis cancer: 10.4"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BEWO: 17.7;HAP1: 20.4;K-562: 12.0;NTERA-2: 11.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019032, HPA057273"			Supported	"Nucleoplasm,Nuclear membrane"		NA	NA			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 69: Cerebellum - Gene expression regulation"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 38: Extravillous trophoblasts - Unknown function"	Nucleoplasm	"Nuclear membrane"	"HPA019032: AB_1847363, HPA057273: AB_2683391"	"unprognostic (1.60e-1)"	"unprognostic (8.30e-2)"	"unprognostic (9.85e-2)"	"unprognostic (1.67e-2)"	"unprognostic (1.27e-1)"	"unprognostic (8.15e-2)"	"unprognostic (3.60e-3)"	"unprognostic (1.12e-1)"	"unprognostic (2.00e-1)"	"unprognostic (7.90e-3)"	"unprognostic (1.83e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.18e-3)"	"unprognostic (2.88e-4)"	"unprognostic (4.02e-2)"	"unprognostic (2.54e-1)"	"unprognostic (9.52e-3)"	0.4	0.2	0.6	0.2	1.2	0.3	0.4	4.9	0.7	0.7	0.8	0.4	0.1	0.9	0.6	0.2	0.5	0.3	0.3	0.3	0.9	0.3	0.2	0.2	0.3	0.9	1.3	0.8	0.2	0.7	0.3	1.2	1.1	0.6	0.3	1.5	1.0	0.3	0.9	0.3	0.2	0.5	1.0	0.3	0.4	0.2	1.1	2.0	0.5	0.3	0.3	0.2	0.4	2.2	0.7	0.8	8.0	9.0	0.8	0.7	17.7	0.4	1.0	0.7	1.2	5.5	0.3	0.0	0.3	0.8	0.1	0.0	20.4	0.0	0.8	0.3	3.3	2.1	0.0	4.9	1.2	1.9	1.0	1.0	0.1	0.5	0.1	1.6	0.1	3.5	12.0	1.4	0.7	0.6	3.3	1.4	11.9	0.0	1.1	3.2	2.5	0.2	0.4	0.8	2.2	3.5	0.4	0.5	1.6	7.9	1.0	1.5	0.3	0.7	1.6	0.0	0.6	0.5	0.6	3.2	0.2	0.0	0.2	0.0	0.0	0.2	0.3	0.0	0.4	0.3	0.1	0.2	0.0	0.1	0.2	0.2	0.0	0.1	0.0	0.2	0.5	0.0	0.6	1.2	4.9	0.7	0.3	0.9	0.9	1.3	1.1	1.0	1.1	2.2	6.3	3.2	6.2	54.5	2.5	1.1	1.8	0.4	5.2	2.5	7.0	9.5	7.2	1.5	2.6	0.0	10.4	21.0	3.0	0.2	0.0	2.7	0.8	3.6	34.2	4.8	13.8	2.5	15.6	0.4	79.9	15.4	1.5	2.9	0.0	13.6	5.7	2.5	3.9	35.3	20.6	0.3	4.1	0.0	0.3	1.7	25.7	0.8	1.8	12.2	0.4	16.1	5.2	44.7	45.3	0.6	0.0	20.7	7.3	1.4	0.0	0.9	0.8	12.5	6.6	21.9	10.7	0.5	1.5	0.8	1.1	27.9	2.6	43.7	0.6	0.4
TET2	"FLJ20032, KIAA1546"	ENSG00000168769	"Tet methylcytosine dioxygenase 2"	Q6N021	4	105145875-105279816	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Cell cycle"	"Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 128.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 55.5"	"Lineage enriched"	"Detected in all"	4	"granulocytes: 55.5"	"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA043135	Supported		Approved	Nucleoplasm		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 41: Macrophages - Immune response"	Nucleoplasm		"HPA043135: AB_10794177"	"unprognostic (6.83e-2)"	"unprognostic (3.52e-2)"	"unprognostic (1.69e-2)"	"unprognostic (9.42e-2)"	"unprognostic (4.15e-2)"	"unprognostic (5.88e-2)"	"unprognostic (6.12e-2)"	"unprognostic (1.19e-3)"	"unprognostic (1.15e-2)"	"unprognostic (1.57e-2)"	"unprognostic (5.77e-2)"	"unprognostic (7.29e-2)"	"unprognostic (2.70e-3)"	"unprognostic (6.10e-2)"	"unprognostic (1.89e-1)"	"unprognostic (9.15e-2)"	"unprognostic (7.84e-2)"	4.3	3.1	2.9	10.1	4.4	22.4	5.4	2.5	2.7	6.3	5.8	5.2	6.1	7.2	6.0	7.7	4.9	5.0	3.3	2.1	4.6	4.1	4.2	5.4	5.6	5.3	4.4	4.3	3.7	4.6	1.8	10.2	5.3	4.4	5.9	6.6	4.7	3.3	2.8	11.0	6.0	5.7	2.9	7.2	5.3	1.3	4.1	5.4	4.2	5.2	7.0	5.5	4.5	5.6	5.1	3.1	10.9	11.1	2.1	3.7	4.2	3.1	4.8	4.8	4.7	3.1	6.4	0.5	4.0	4.0	2.1	4.9	9.3	6.1	5.3	6.7	2.9	7.0	6.5	1.6	4.9	15.5	11.8	3.8	7.9	4.5	5.6	8.6	6.4	4.1	7.7	13.6	4.4	3.1	2.5	4.7	2.5	6.2	2.2	8.4	4.7	1.0	4.7	9.4	7.5	5.9	4.2	9.1	0.8	5.9	4.5	11.8	9.1	7.8	6.7	2.1	5.3	9.5	6.8	6.8	4.8	3.8	7.2	30.1	13.6	14.7	3.9	10.4	1.6	5.3	2.3	2.2	10.2	6.3	1.9	2.9	55.5	5.9	13.6	8.9	3.1	3.3	2.9	4.4	2.5	2.7	2.1	4.6	5.3	4.4	5.3	2.9	4.1	5.6	24.5	25.6	29.1	58.8	28.3	14.4	11.0	14.2	12.5	22.8	15.6	13.6	27.9	5.7	23.9	9.2	16.7	23.1	34.1	19.0	7.9	7.0	0.4	22.1	38.3	20.3	23.3	10.9	48.4	7.5	5.7	18.0	21.4	33.2	27.8	15.5	13.6	8.5	14.5	35.3	89.7	15.8	32.6	48.8	93.3	0.9	8.1	98.3	5.4	90.9	48.1	5.8	34.0	112.6	128.3	8.2	18.7	7.2	22.5	12.1	16.3	2.8	22.3	24.3	13.1	47.0	21.7	0.2	1.3	28.4	35.9	34.2	18.9	24.7	14.0	27.5
TET3	"hCG_40738, MGC22014"	ENSG00000187605	"Tet methylcytosine dioxygenase 3"	O43151	2	73984910-74108176	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"		"Chromatin regulator, Developmental protein, Dioxygenase, DNA-binding, Oxidoreductase"	"Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 19.7;skin 1: 16.2"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 88.5;Oligodendrocytes: 86.7;Suprabasal keratinocytes: 68.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA050845	Uncertain		Approved	Nucleoplasm,Vesicles,Cytosol		NA	NA				"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 44: Endometrium - Transcription"	Nucleoplasm	"Vesicles, Cytosol"	"HPA050845: AB_2681256"	"unprognostic (1.07e-2)"	"unprognostic (1.21e-2)"	"unprognostic (3.08e-1)"	"unprognostic (1.12e-2)"	"unprognostic (4.44e-2)"	"unprognostic (2.75e-2)"	"unprognostic (1.72e-3)"	"unprognostic (1.46e-1)"	"unprognostic (1.01e-1)"	"unprognostic (9.83e-2)"	"unprognostic (7.74e-2)"	"unprognostic (2.03e-1)"	"prognostic unfavorable (3.58e-5)"	"unprognostic (2.05e-1)"	"unprognostic (5.30e-1)"	"unprognostic (1.55e-2)"	"unprognostic (1.10e-1)"	2.2	1.6	3.7	5.2	2.4	19.7	3.0	6.3	13.7	2.5	0.0	4.1	5.4	2.0	1.4	7.6	1.9	2.5	1.2	9.3	1.7	1.6	3.9	4.1	3.7	2.0	1.5	1.5	2.6	2.0	1.5	4.6	2.2	2.5	4.3	3.6	4.2	1.1	1.2	16.2	6.0	2.1	0.6	3.8	4.3	1.6	2.7	5.8	2.3	1.3	4.1	3.4	4.0	5.8	9.0	8.0	14.5	8.9	1.2	1.3	26.4	1.8	2.4	3.4	2.7	16.6	8.1	14.9	3.5	2.4	1.6	9.4	13.0	5.2	3.6	6.7	5.2	19.2	7.0	5.6	5.1	20.2	11.3	2.0	13.3	4.2	9.9	4.3	5.3	10.3	13.4	4.8	2.0	14.6	10.0	13.0	8.1	7.7	2.7	15.4	9.1	5.2	3.8	16.5	18.1	15.5	4.0	10.3	4.9	5.7	6.6	16.1	6.7	3.7	15.4	1.8	6.8	4.2	2.0	12.7	2.4	13.9	4.9	0.1	0.4	0.2	0.0	0.4	0.1	0.2	0.1	0.1	0.2	0.1	0.1	0.1	0.4	0.1	0.1	0.2	0.1	0.2	3.7	2.4	6.3	13.7	9.3	1.7	2.0	1.5	2.2	0.6	2.7	5.8	4.2	6.4	9.0	31.3	6.4	49.5	3.5	4.2	14.8	16.3	8.0	5.8	2.9	2.8	8.0	1.8	20.9	7.0	7.3	10.5	0.0	3.5	4.7	18.8	11.9	6.6	6.0	24.8	88.5	4.4	30.1	3.4	13.7	29.6	2.5	6.2	3.6	6.1	10.1	10.1	45.7	8.0	8.2	26.9	23.2	0.8	0.6	26.9	10.6	54.4	27.1	1.5	2.1	41.7	86.7	6.2	7.7	3.0	4.8	6.2	10.3	1.5	11.9	8.6	0.0	3.8	7.7	0.5	2.6	24.4	68.2	2.5	5.5	2.3	6.9	7.0
TH	DYT5b	ENSG00000180176	"Tyrosine hydroxylase"	P07101	11	2163929-2171815	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Catecholamine biosynthesis, Neurotransmitter biosynthesis"	"Monooxygenase, Oxidoreductase"	"Disease variant, Dystonia, FDA approved drug targets, Parkinson disease, Parkinsonism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	69	"adrenal gland: 196.6;brain: 270.9"	"Cell type enhanced"	"Detected in some"		"Endometrial stromal cells: 9.0;Extravillous trophoblasts: 12.4;Leydig cells: 3.4;Syncytiotrophoblasts: 2.2"	"Cancer enriched"	"Detected in some"	5	"urothelial cancer: 4.0"	"Group enriched"	"Detected in many"	5	"midbrain: 192.4;pons: 270.9"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	30	"PC-3: 60.8;SK-BR-3: 21.0"	"Region enhanced"	"Detected in many"		"olfactory bulb: 178.8"	"Region enriched"	"Detected in many"	20	"midbrain: 594.4"	"CAB002522, HPA013768, HPA014010, HPA061003, CAB072340"	Enhanced	Supported	Approved	Cytosol		NA	NA				"Cluster 73: Brain - Neuropeptide signaling"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 38: Extravillous trophoblasts - Unknown function"	Cytosol		"CAB002522: AB_564047, CAB072340: , HPA013768: , HPA014010: , HPA061003: AB_2630374"	"unprognostic (1.31e-1)"	"unprognostic (1.30e-1)"	"unprognostic (9.08e-2)"	"unprognostic (1.75e-4)"	"unprognostic (8.82e-3)"	"unprognostic (5.88e-2)"	"unprognostic (1.93e-1)"	"unprognostic (1.74e-3)"	"unprognostic (3.83e-2)"	"unprognostic (4.39e-4)"	"unprognostic (4.97e-1)"	"unprognostic (3.61e-2)"	"unprognostic (1.92e-1)"	"unprognostic (1.60e-1)"	"unprognostic (2.43e-1)"	"unprognostic (2.70e-2)"	"unprognostic (2.18e-2)"	3.3	196.6	1.9	0.1	3.0	0.0	0.0	0.2	1.3	0.6	0.2	0.1	0.0	0.5	0.1	0.7	0.2	0.4	0.1	1.3	46.5	0.4	0.4	0.0	0.0	13.9	192.4	0.7	0.2	0.0	1.7	0.1	270.9	0.3	0.0	0.1	0.1	0.0	0.0	0.8	0.5	0.0	0.8	0.2	0.3	0.5	14.6	0.0	0.0	0.0	0.0	1.4	1.5	1.6	0.0	0.0	0.1	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.5	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.3	0.0	0.0	0.0	0.6	60.8	0.0	0.0	0.0	0.1	0.1	1.1	0.2	0.0	21.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.9	3.0	0.2	1.3	1.3	46.5	13.9	192.4	270.9	0.8	14.6	1.6	0.3	0.0	0.0	0.0	0.5	0.1	0.1	0.2	0.0	0.0	0.0	0.1	0.9	0.0	0.2	1.8	0.0	0.2	0.0	0.1	0.0	0.1	0.1	0.4	9.0	0.4	0.0	0.0	0.1	0.0	12.4	0.4	0.0	0.3	0.0	0.0	1.1	0.2	0.5	0.0	0.3	0.1	0.0	0.0	0.3	0.2	3.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.7	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	1.6	0.0	0.0	2.2	0.1	0.3	0.2	0.2
TM7SF2	"ANG1, DHCR14A, NET47"	ENSG00000149809	"Transmembrane 7 superfamily member 2"	O76062	11	65111845-65116384	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adrenal gland: 246.0"	"Cell type enhanced"	"Detected in all"		"Granulosa cells: 482.7;Hepatocytes: 220.6;Muller glia cells: 204.7;Theca cells: 204.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"plasmacytoid DC: 38.1"	"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"MCF7: 69.2;RPTEC TERT1: 86.2;T-47d: 143.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA030691, HPA072704"	Enhanced		Supported	"Endoplasmic reticulum,Vesicles"		NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 35: Non-specific - Unknown function"	"Cluster 6: T47d - Mammary gland"	"Cluster 40: Granulosa cells - Unknown function"	"Endoplasmic reticulum"	Vesicles	"HPA030691: AB_10602480, HPA072704: AB_2686551"	"unprognostic (1.62e-1)"	"unprognostic (5.23e-2)"	"unprognostic (1.70e-2)"	"unprognostic (1.78e-1)"	"unprognostic (5.74e-2)"	"unprognostic (1.10e-1)"	"unprognostic (5.98e-2)"	"unprognostic (6.06e-2)"	"unprognostic (5.72e-2)"	"unprognostic (1.74e-2)"	"unprognostic (7.06e-2)"	"unprognostic (1.69e-1)"	"prognostic favorable (8.49e-8)"	"unprognostic (8.77e-2)"	"unprognostic (1.90e-1)"	"unprognostic (1.35e-1)"	"unprognostic (3.44e-2)"	63.4	246.0	27.8	2.6	28.5	4.1	29.1	32.8	33.9	17.4	64.1	7.8	9.4	3.4	17.0	39.6	12.8	7.0	47.3	30.0	29.7	18.9	86.4	10.1	3.4	34.0	32.0	36.5	69.9	36.3	19.5	3.9	32.5	41.1	3.9	6.0	46.9	6.0	7.1	68.2	8.3	1.9	30.1	5.1	35.6	11.5	32.6	5.6	15.5	3.7	8.4	5.5	22.1	35.1	7.7	10.9	27.3	35.1	8.1	1.3	15.4	1.8	4.5	2.7	3.0	26.0	35.8	16.3	26.9	2.2	1.0	13.3	11.6	21.2	1.9	16.7	5.0	10.2	2.7	54.5	18.8	4.2	10.6	3.7	5.0	14.6	3.9	12.6	3.9	28.7	5.8	13.9	0.8	69.2	8.3	18.6	12.6	18.4	11.2	22.4	1.2	39.9	86.2	12.6	27.2	30.5	1.2	28.2	6.1	19.5	143.9	11.4	3.1	0.4	3.4	3.8	2.3	27.1	18.1	8.4	2.5	5.9	1.0	1.1	1.6	3.4	9.1	1.5	7.0	12.4	5.6	7.8	1.5	11.9	11.8	9.0	1.1	12.5	0.9	38.1	5.6	4.9	27.8	28.5	32.8	33.9	30.0	29.7	34.0	32.0	32.5	30.1	32.6	35.1	4.0	9.6	43.7	23.5	12.7	1.9	6.2	33.6	5.7	19.2	52.2	38.5	99.4	52.9	36.6	44.1	10.4	72.9	16.3	23.3	17.6	27.1	28.8	17.9	2.6	5.7	59.4	13.7	11.6	27.7	4.6	4.3	31.1	16.5	7.0	482.7	5.0	220.6	15.6	25.2	15.3	21.8	52.9	6.3	2.7	59.3	9.9	5.8	12.4	2.8	9.4	204.7	7.2	17.1	36.5	21.7	23.7	2.2	12.9	31.3	29.0	77.5	37.9	23.6	13.1	1.6	21.8	13.3	17.9	18.0	7.0	82.1	8.3	204.8	19.0	10.4
TMLHE	"BBOX2, FLJ10727, TMLH, XAP130"	ENSG00000185973	"Trimethyllysine hydroxylase, epsilon"	Q9NVH6	X	155489011-155719098	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Carnitine biosynthesis"	"Dioxygenase, Oxidoreductase"	"Autism, Autism spectrum disorder, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Microglial cells: 51.5;Oligodendrocyte precursor cells: 47.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"							"Low region specificity"	"Detected in all"			"HPA034589, HPA040331"	Approved		Supported	Mitochondria		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 38: EFO-21 - Unknown function"	"Cluster 68: Oligodendrocytes - Mixed function"	Mitochondria		"HPA034589: AB_10670571, HPA040331: AB_2676929"	"unprognostic (1.98e-1)"	"unprognostic (9.15e-2)"	"unprognostic (3.04e-1)"	"unprognostic (5.41e-2)"	"unprognostic (6.66e-3)"	"unprognostic (1.10e-3)"	"unprognostic (6.50e-2)"	"unprognostic (1.00e-1)"	"unprognostic (3.27e-1)"	"unprognostic (4.08e-2)"	"unprognostic (1.20e-3)"	"unprognostic (6.97e-2)"	"prognostic favorable (3.68e-6)"	"unprognostic (1.69e-1)"	"unprognostic (5.74e-2)"	"unprognostic (2.73e-1)"	"unprognostic (7.75e-2)"	11.7	10.2	7.1	6.6	7.4	8.4	11.3	9.0	8.0	11.3	8.1	11.6	11.8	9.4	10.4	10.3	9.9	8.0	25.3	6.7	7.7	16.7	18.8	5.6	7.0	8.5	8.2	12.0	9.5	18.9	5.4	8.4	8.5	6.6	12.5	10.9	12.7	9.7	32.0	5.9	11.2	12.3	8.3	8.7	9.1	2.9	7.3	8.9	10.5	33.4	7.6	8.2	6.6	9.8	25.0	11.9	9.8	28.6	11.8	18.1	0.0	9.9	14.6	12.3	32.4	8.7	13.9	0.0	38.9	17.6	28.2	13.4	21.2	9.7	13.9	10.3	14.3	11.3	19.5	10.2	16.4	10.5	7.6	19.5	20.0	13.6	20.8	18.2	19.5	15.5	15.8	9.0	20.5	9.3	12.8	11.8	3.0	21.6	0.1	12.7	15.5	9.4	15.0	8.5	9.2	13.7	9.3	0.5	11.2	10.5	10.6	11.9	16.5	10.3	9.7	20.4	12.4	11.0	12.6	9.6	12.4	16.4	9.6	3.4	12.6	14.7	4.6	14.9	3.5	8.1	5.0	3.9	13.1	10.6	6.5	5.7	18.2	6.2	21.5	6.1	5.5	5.8	7.1	7.4	9.0	8.0	6.7	7.7	8.5	8.2	8.5	8.3	7.3	9.8	6.7	0.0	2.3	27.1	10.1	5.2	12.1	14.4	9.6	4.0	5.2	7.5	7.2	7.2	9.7	9.2	0.0	8.8	6.5	7.9	23.5	10.7	0.0	6.8	7.4	6.2	6.1	14.3	22.2	7.6	6.8	10.2	9.2	7.3	10.1	8.1	4.2	12.0	12.4	0.0	29.5	7.3	4.1	16.1	10.4	0.5	8.4	12.1	12.4	51.5	13.1	7.6	10.3	47.7	25.5	8.5	7.3	5.7	5.6	4.3	17.4	17.0	9.5	5.4	0.0	5.9	9.5	0.3	2.5	7.6	4.1	6.7	8.0	10.5	6.5	11.0
TPH1	"TPH, TPRH"	ENSG00000129167	"Tryptophan hydroxylase 1"	P17752	11	18017564-18042426	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins"	"Serotonin biosynthesis"	"Monooxygenase, Oxidoreductase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"brain: 9.0;intestine: 19.3;stomach 1: 15.0"	"Cell type enriched"	"Detected in many"	30	"Enteroendocrine cells: 1466.7"	"Cancer enhanced"	"Detected in some"		"endometrial cancer: 2.4"	"Group enriched"	"Detected in some"	5	"hypothalamus: 3.4;midbrain: 9.0"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HL-60: 1.5"	"Low region specificity"	"Detected in some"							"CAB010767, HPA022483"	Uncertain		Uncertain	Cytosol		NA	NA				"Cluster 9: Intestine - Unknown function"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 17: Intestinal endocrine cells - Hormone signaling"	Cytosol		"CAB010767: AB_261587, HPA022483: AB_1858378"	"unprognostic (2.14e-4)"	"unprognostic (9.97e-2)"	"unprognostic (6.92e-2)"	"unprognostic (6.78e-2)"	"unprognostic (1.55e-1)"	"unprognostic (6.26e-5)"	"unprognostic (1.73e-1)"	"unprognostic (5.33e-2)"	"unprognostic (1.60e-1)"	"unprognostic (2.12e-2)"	"unprognostic (1.19e-4)"	"unprognostic (6.72e-2)"	"unprognostic (5.40e-8)"	"unprognostic (3.76e-2)"	"unprognostic (7.42e-2)"	"unprognostic (3.10e-1)"	"unprognostic (2.46e-5)"	0.6	0.1	0.2	1.2	0.3	1.1	1.3	0.3	0.3	0.6	4.7	9.0	10.2	0.9	0.9	0.2	0.9	0.1	0.3	0.4	3.4	0.5	0.2	0.8	0.5	0.2	9.0	0.7	0.5	0.1	3.0	0.2	1.1	1.4	19.3	1.8	0.5	0.1	0.4	1.4	11.2	0.2	0.2	0.7	15.0	0.9	0.4	0.3	0.5	0.1	0.7	0.4	0.4	0.3	0.1	0.0	0.5	0.4	0.0	0.0	0.2	0.1	0.1	0.0	0.3	0.6	0.0	0.4	0.1	0.0	0.0	0.2	0.1	0.5	0.2	0.4	1.0	0.7	0.3	1.1	0.0	1.5	0.3	0.0	0.6	0.0	0.2	0.1	0.2	0.8	0.3	0.2	0.0	0.1	0.3	0.2	0.1	0.0	0.1	0.5	0.0	0.0	0.0	0.3	0.4	0.3	0.0	0.1	0.2	0.0	0.0	0.9	0.0	0.1	0.4	0.1	0.5	0.0	0.1	0.3	0.0	0.3	0.4	0.3	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2	0.1	0.0	0.1	0.0	0.0	0.2	0.3	0.3	0.3	0.4	3.4	0.2	9.0	1.1	0.2	0.4	0.3	1.4	0.0	0.0	1.0	1.1	0.4	0.4	0.5	0.0	14.9	1.9	1.0	0.8	0.0	0.1	5.5	2.1	0.2	0.6	1.7	0.0	0.2	0.8	0.1	0.6	0.7	1466.7	0.4	0.5	0.6	0.0	1.2	2.0	0.2	0.0	5.6	0.4	0.2	0.2	1.7	0.4	48.2	0.0	0.3	1.4	0.8	0.9	0.5	0.0	0.0	0.1	1.4	1.0	0.0	0.6	0.4	13.4	1.2	0.3	2.3	1.5	0.3	0.9	5.6	6.6	1.3	1.3	2.8	3.7	0.0	1.4	0.0	1.2	0.0	2.7	0.4
TPH2	"FLJ37295, NTPH"	ENSG00000139287	"Tryptophan hydroxylase 2"	Q8IWU9	12	71938845-72186618	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Serotonin biosynthesis"	"Monooxygenase, Oxidoreductase"	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	716	"brain: 325.8"	"Group enriched"	"Detected in some"	5	"Early spermatids: 8.0;Inhibitory neurons: 3.2;Late spermatids: 7.4;Spermatogonia: 3.7"	"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	5	"midbrain: 325.8;pons: 141.5"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	31	"midbrain: 106.7;pons and medulla: 34.9"	"Group enriched"	"Detected in some"	5	"midbrain: 49.9;pons: 49.6"	CAB078198	Enhanced					NA	NA				"Cluster 73: Brain - Neuropeptide signaling"		"Cluster 34: Spermatids - Unknown function"			"CAB078198: AB_2665804"	"unprognostic (1.19e-1)"	"unprognostic (6.01e-1)"		"unprognostic (3.46e-2)"	"unprognostic (2.31e-1)"				"unprognostic (5.91e-2)"	"unprognostic (2.02e-1)"	"unprognostic (5.01e-2)"			"unprognostic (7.32e-2)"	"unprognostic (1.34e-1)"			0.0	0.0	0.2	0.0	0.2	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.4	0.0	0.0	0.0	0.0	45.3	325.8	0.0	0.2	0.0	0.4	0.0	141.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.2	0.0	0.3	1.0	0.4	45.3	325.8	141.5	0.1	0.4	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	8.0	0.2	0.1	0.1	0.0	0.0	1.0	0.0	0.0	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	3.2	0.0	0.0	0.0	0.0	7.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.3	0.1	0.7	3.7	0.0	0.0	0.0	0.0	0.0	0.0	0.1
TPO	TPX	ENSG00000115705	"Thyroid peroxidase"	P07202	2	1374066-1543711	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Hydrogen peroxide, Thyroid hormones biosynthesis"	"Oxidoreductase, Peroxidase"	"Congenital hypothyroidism, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	70	"thyroid gland: 1588.2"	"Cell type enhanced"	"Detected in some"		"Adipocytes: 24.5;Early spermatids: 4.2;Endothelial cells: 12.6;Late spermatids: 7.5;Peritubular cells: 3.8"	"Cancer enriched"	"Detected in some"	364	"thyroid cancer: 188.3"	"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	12	"memory CD4 T-cell: 2.0;T-reg: 1.2"	"Lineage enriched"	"Detected in single"	20	"T-cells: 2.0"	"Group enriched"	"Detected in some"	5	"Karpas-707: 9.9;RPMI-8226: 3.9"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA007987, CAB009587"	Enhanced				"Intracellular and membrane"	NA	NA			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 1: Thyroid gland - Transcription"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"			"CAB009587: , HPA007987: AB_1080270"	"unprognostic (1.55e-1)"	"unprognostic (1.04e-1)"	"unprognostic (2.88e-1)"	"unprognostic (1.77e-2)"	"unprognostic (3.56e-2)"	"unprognostic (9.11e-2)"	"unprognostic (2.24e-2)"	"unprognostic (1.85e-1)"	"unprognostic (1.32e-1)"	"unprognostic (1.19e-4)"	"unprognostic (2.61e-2)"	"unprognostic (3.29e-1)"	"unprognostic (5.44e-4)"	"unprognostic (1.21e-1)"	"unprognostic (3.73e-2)"	"unprognostic (4.98e-3)"	"unprognostic (7.10e-3)"	13.1	0.3	0.1	0.4	0.0	0.1	11.0	0.0	0.6	0.1	0.0	4.6	0.6	0.6	0.0	2.0	0.7	3.0	11.5	0.1	0.2	0.2	0.6	0.8	1.4	0.2	0.1	0.3	2.3	0.3	0.6	0.0	0.1	0.6	0.9	0.2	3.4	0.0	6.0	1.8	3.8	0.6	0.1	22.8	2.8	1.2	0.2	0.0	1588.2	5.6	0.4	2.1	1.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.1	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	9.9	0.0	1.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	3.9	0.0	0.0	0.0	0.0	0.0	1.4	0.0	0.0	0.8	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	1.2	0.2	0.1	0.0	0.0	0.6	0.1	0.2	0.2	0.1	0.1	0.1	0.2	0.4	24.5	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	2.9	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	4.2	0.0	0.2	12.6	0.0	0.0	2.4	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	7.5	0.6	0.4	0.0	0.0	0.0	0.0	0.0	1.0	0.3	0.0	1.1	3.8	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.4	0.8	0.3	0.5	0.1	0.0	0.0	0.2	0.1	0.0	0.1
TXNDC12	"AGR1, ERP18, ERP19, hAG-1, PDIA16, TLP19"	ENSG00000117862	"Thioredoxin domain containing 12"	O95881	1	52020131-52055191	"Enzymes, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"								"Intracellular and membrane"	NA	NA		160000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 55: Plasma cells - Humoral immune response"				"unprognostic (6.54e-2)"	"unprognostic (5.46e-2)"	"prognostic favorable (4.44e-4)"	"unprognostic (2.33e-3)"	"unprognostic (2.19e-1)"	"prognostic unfavorable (2.61e-4)"	"prognostic unfavorable (1.28e-5)"	"unprognostic (1.25e-1)"	"unprognostic (3.28e-2)"	"unprognostic (1.17e-1)"	"unprognostic (6.14e-2)"	"unprognostic (2.42e-1)"	"prognostic unfavorable (1.40e-12)"	"unprognostic (2.13e-1)"	"unprognostic (5.83e-2)"	"unprognostic (1.73e-2)"	"unprognostic (1.17e-1)"	49.6	47.7	39.7	45.7	40.7	51.3	50.8	41.2	48.0	49.2	44.2	60.8	47.0	40.8	62.9	31.2	56.8	46.5	36.6	40.1	47.0	54.0	74.1	46.9	50.1	42.5	41.6	47.8	56.5	46.7	21.9	54.5	43.1	40.8	66.1	28.6	57.6	36.5	18.2	29.9	48.4	40.8	44.1	46.4	56.4	38.9	42.8	52.3	52.6	30.2	54.4	57.5	18.0	46.1	97.1	88.9	96.0	135.4	160.1	83.9	76.4	143.5	143.8	132.7	150.7	99.8	78.2	73.0	93.8	118.1	141.1	127.3	134.5	112.9	178.2	94.1	124.2	93.1	73.3	163.2	165.7	176.8	181.8	120.5	132.0	134.0	203.3	99.0	135.4	89.1	87.1	48.2	111.9	91.4	89.3	233.6	208.0	138.8	85.9	94.2	143.3	207.1	178.6	85.3	68.3	97.3	143.9	123.5	138.7	187.7	69.6	228.1	86.5	93.9	100.1	106.7	166.1	107.2	183.6	84.2	131.0	164.9	108.2	355.3	224.0	356.5	135.3	215.0	170.8	160.1	164.3	145.3	169.2	146.0	156.7	151.1	393.2	150.0	234.2	180.6	220.0	273.3	39.7	40.7	41.2	48.0	40.1	47.0	42.5	41.6	43.1	44.1	42.8	46.1	89.8	9.6	12.3	9.4	50.4	44.1	63.1	78.9	35.3	18.3	53.6	57.0	13.6	62.9	30.4	44.1	14.6	115.5	58.9	35.3	17.6	75.4	13.3	42.5	54.7	62.3	48.5	25.7	15.0	89.4	170.9	52.1	23.4	49.2	33.0	106.3	55.6	31.0	120.8	21.9	14.7	70.5	50.8	59.1	55.7	7.2	55.9	66.0	51.6	19.7	66.6	39.2	50.4	10.1	15.9	73.0	57.0	30.9	68.7	68.7	65.4	36.1	32.3	17.0	32.9	40.7	47.1	60.4	9.7	36.0	45.5	118.5	52.3	75.4	71.2	60.4
TXNRD1	"GRIM-12, Trxr1, TXNR"	ENSG00000198431	"Thioredoxin reductase 1"	Q16881	12	104215779-104350307	"Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Electron transport, Transport"	Oxidoreductase	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Basal prostatic cells: 459.7;Prostatic glandular cells: 557.4;Urothelial cells: 488.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"fHDF/TERT166: 1452.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001395, CAB004607, CAB015834, HPA043871"	Approved		Supported	Nucleoplasm		NA	NA		6100000	"Cluster 46: Basophils - DNA binding"	"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 22: Epithelial cell types - Mixed function"	Nucleoplasm		"CAB004607: AB_628405, CAB015834: , HPA001395: AB_1858377, HPA043871: AB_2678709"	"unprognostic (2.52e-2)"	"unprognostic (1.16e-1)"	"unprognostic (5.48e-2)"	"unprognostic (1.01e-1)"	"unprognostic (3.15e-1)"	"unprognostic (1.94e-2)"	"prognostic unfavorable (1.12e-5)"	"unprognostic (5.55e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.08e-1)"	"unprognostic (6.42e-2)"	"unprognostic (2.21e-1)"	"prognostic unfavorable (1.20e-5)"	"unprognostic (2.13e-1)"	"unprognostic (1.27e-1)"	"unprognostic (1.18e-2)"	"unprognostic (8.80e-2)"	47.1	148.1	22.5	40.6	21.1	64.7	28.0	20.9	22.6	28.0	37.3	50.9	58.4	47.9	21.0	30.7	39.0	55.9	65.8	21.1	29.8	37.9	46.5	63.0	34.4	55.2	26.7	34.1	19.0	33.8	21.2	39.1	33.3	41.0	45.6	20.1	20.8	60.6	67.8	12.4	39.4	51.6	22.9	27.8	52.1	37.8	24.6	42.8	30.4	64.0	34.1	141.6	30.1	25.7	228.4	1032.6	118.1	111.3	553.5	308.0	409.8	412.4	259.3	182.7	186.8	110.5	329.4	169.3	187.0	1452.6	682.1	77.7	235.7	158.6	214.1	82.7	101.8	143.1	765.8	468.0	885.7	226.3	149.9	176.9	159.8	403.7	128.1	557.1	634.0	227.9	200.5	77.5	276.8	109.1	233.4	102.7	114.4	453.0	1053.1	227.3	82.1	146.5	211.2	123.1	182.6	110.6	333.3	519.1	325.2	222.6	123.2	131.4	854.5	89.3	183.7	201.3	341.2	84.8	179.9	254.5	186.8	122.5	538.0	109.4	29.9	69.7	23.6	39.0	26.9	21.3	21.6	23.9	39.5	14.5	19.1	16.7	102.6	24.4	48.4	25.2	19.8	27.6	22.5	21.1	20.9	22.6	21.1	29.8	55.2	26.7	33.3	22.9	24.6	25.7	26.0	64.1	67.5	50.3	27.6	104.0	459.7	41.3	40.9	28.1	19.4	16.3	66.2	32.9	79.3	16.5	22.9	26.1	40.4	93.4	41.1	79.6	45.0	100.9	36.8	116.2	20.4	46.3	48.2	80.7	34.3	90.1	69.8	119.6	53.2	35.2	49.2	68.2	42.0	28.6	56.7	18.8	44.7	43.5	100.5	19.1	68.0	62.2	19.6	49.6	51.9	24.8	26.8	29.1	55.3	197.7	40.5	29.3	28.4	557.4	24.6	37.5	105.5	20.9	0.0	43.4	84.0	14.4	33.8	24.3	72.9	51.3	28.5	98.4	33.0	488.0
TXNRD2	"SELZ, TR, TR3, TRXR2"	ENSG00000184470	"Thioredoxin reductase 2"	Q9NNW7	22	19875517-19941820	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"U-2 OS: 139.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002007, HPA003323"	Supported		Approved	Mitochondria,Cytosol		NA	NA		2800000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 47: Cytotrophoblasts - Unknown function"	"Mitochondria, Cytosol"		"CAB002007: , HPA003323: AB_1080396"	"unprognostic (3.17e-2)"	"unprognostic (8.72e-2)"	"unprognostic (4.30e-1)"	"unprognostic (9.71e-3)"	"unprognostic (7.25e-2)"	"unprognostic (6.35e-2)"	"unprognostic (3.21e-1)"	"unprognostic (1.12e-1)"	"unprognostic (2.78e-1)"	"unprognostic (2.83e-1)"	"unprognostic (4.94e-3)"	"unprognostic (2.49e-1)"	"prognostic favorable (1.10e-7)"	"unprognostic (2.47e-1)"	"unprognostic (5.99e-2)"	"unprognostic (1.69e-1)"	"unprognostic (1.10e-1)"	10.5	44.4	11.9	8.9	12.0	14.5	12.3	18.1	19.3	11.7	21.2	14.9	10.3	10.6	6.2	10.2	10.6	6.2	30.0	12.9	11.9	24.8	65.4	13.6	9.1	11.8	12.1	16.5	15.9	13.5	14.4	9.8	11.5	26.8	4.6	4.4	15.4	8.2	23.0	10.9	12.0	5.1	11.3	16.9	26.4	14.6	12.4	4.9	15.2	16.1	6.1	11.8	10.4	11.8	19.4	39.2	3.5	14.9	6.9	9.6	8.8	18.8	21.1	31.8	23.4	36.7	19.4	10.9	43.2	19.0	32.7	33.2	17.8	25.2	12.1	21.6	46.5	18.8	34.4	22.4	12.9	21.1	8.4	9.2	18.5	16.2	13.8	12.9	91.3	2.2	106.4	17.4	24.8	47.1	7.2	30.1	17.7	46.9	27.6	10.5	85.2	10.0	19.3	21.0	19.1	16.4	32.0	39.9	21.8	5.8	33.7	27.6	52.2	23.0	139.5	19.8	38.4	17.6	14.0	6.9	22.4	15.5	30.3	2.7	10.5	5.8	3.5	8.2	2.6	3.9	3.0	3.2	7.8	2.6	3.9	3.2	0.9	3.8	7.9	2.9	2.1	4.6	11.9	12.0	18.1	19.3	12.9	11.9	11.8	12.1	11.5	11.3	12.4	11.8	5.6	16.0	23.6	11.1	10.3	4.2	23.1	15.1	3.4	22.1	11.4	9.1	16.7	15.7	15.7	20.2	10.4	60.7	8.8	14.7	58.7	22.0	26.4	9.8	8.4	14.4	1.2	33.1	9.2	32.0	24.3	12.4	23.4	10.0	1.3	27.6	8.9	49.5	25.9	10.1	8.5	16.9	20.3	22.0	7.8	18.2	15.5	14.6	5.4	10.3	27.2	18.7	10.3	8.5	7.2	22.3	13.9	9.1	12.2	17.8	15.6	52.0	16.6	11.0	6.6	11.3	13.3	10.9	14.0	6.4	5.3	42.0	11.4	36.4	16.4	15.7
TXNRD3	"TGR, TR2, TR2IT1, TRXR3, TXNRD3IT1, TXNRD3NB, TXNRD3NT1"	ENSG00000197763	"Thioredoxin reductase 3"	Q86VQ6	3	126571779-126655124	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Differentiation, Electron transport, Spermatogenesis, Transport"	"Developmental protein, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"testis: 20.4"	"Cell type enhanced"	"Detected in many"		"Spermatocytes: 71.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"naive CD4 T-cell: 1.0"	"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB020802, HPA036109"	Uncertain		Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis"	Nucleoplasm	Cytosol	"CAB020802: , HPA036109: AB_2674945"	"unprognostic (1.41e-1)"	"unprognostic (1.55e-2)"	"unprognostic (3.92e-1)"	"prognostic unfavorable (3.35e-4)"	"unprognostic (3.90e-1)"	"unprognostic (2.96e-1)"	"unprognostic (3.01e-1)"	"unprognostic (3.39e-2)"	"unprognostic (1.07e-1)"	"unprognostic (1.03e-1)"	"prognostic unfavorable (2.86e-4)"	"unprognostic (3.14e-1)"	"prognostic favorable (2.72e-4)"	"unprognostic (5.94e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.03e-2)"	"unprognostic (2.51e-1)"	4.9	4.0	2.4	2.2	2.4	1.1	6.1	3.4	1.9	4.7	3.1	2.4	1.3	5.1	5.9	4.8	3.6	3.6	3.1	1.8	3.3	5.7	8.7	4.2	1.1	2.8	3.0	6.7	6.3	8.2	1.7	2.9	2.8	3.8	3.0	1.9	3.7	4.1	5.6	3.2	1.4	4.9	3.0	2.6	3.6	20.4	3.0	4.6	6.1	5.8	1.4	3.2	1.9	2.8	16.0	3.8	4.9	8.3	8.7	13.1	2.7	6.7	5.8	5.4	7.4	7.6	8.7	0.0	8.5	9.7	3.4	6.4	6.3	7.1	6.4	0.0	5.1	1.5	3.7	5.9	7.8	6.4	0.6	13.1	5.9	1.8	12.1	7.0	3.8	5.2	3.7	0.0	9.0	12.2	1.4	3.4	7.3	4.3	3.4	0.5	4.2	2.6	6.0	8.0	8.9	5.1	19.9	5.7	10.3	3.7	8.0	2.6	6.9	6.8	1.8	9.3	3.3	4.0	1.9	0.0	3.5	2.2	5.6	0.0	0.2	0.1	0.1	0.2	0.0	0.0	0.0	0.1	0.2	0.0	1.0	0.3	0.0	0.2	0.0	0.0	0.0	0.1	2.4	2.4	3.4	1.9	1.8	3.3	2.8	3.0	2.8	3.0	3.0	2.8	1.3	3.2	7.2	14.4	0.4	1.0	5.7	1.6	6.2	2.0	2.9	2.4	4.1	4.3	3.0	3.7	2.1	9.4	0.1	0.5	3.9	5.1	18.2	1.5	4.0	1.7	4.2	3.0	7.5	3.8	5.4	5.3	4.1	1.0	5.7	6.1	2.9	8.0	2.9	0.0	5.8	2.4	0.0	0.8	0.7	4.0	4.7	1.0	0.0	3.7	0.0	3.2	0.0	11.1	4.7	3.8	0.3	8.6	0.1	5.5	0.1	4.5	3.3	0.9	0.0	5.7	2.8	71.5	18.2	6.1	0.6	7.3	0.6	6.6	1.5	3.2
TYR	"OCA1, OCA1A, OCAIA"	ENSG00000077498	Tyrosinase	P14679	11	89177875-89295759	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins"	"Melanin biosynthesis"	"Monooxygenase, Oxidoreductase, Tumor antigen"	"Albinism, Deafness, Disease variant, FDA approved drug targets, Waardenburg syndrome"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	37	"skin 1: 31.6"	"Cell type enriched"	"Detected in some"	5	"Melanocytes: 184.9"	"Cancer enriched"	"Detected in single"	1755	"melanoma: 351.3"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in single"	995	"SK-MEL-30: 426.0"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"CAB000079, HPA043241, HPA050889, HPA064583"	Enhanced		Enhanced	Vesicles		NA	NA				"Cluster 61: Skin - Cornification"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 23: Spermatids - Flagellum & Golgi organization"	Vesicles		"CAB000079: AB_564045, HPA043241: AB_2678383, HPA050889: AB_2681264, HPA064583: "	"unprognostic (1.16e-1)"								"unprognostic (1.01e-1)"		"unprognostic (1.85e-3)"		"unprognostic (9.75e-3)"					0.0	0.0	0.0	0.0	0.0	0.1	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.3	0.0	0.0	31.6	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	426.0	0.0	0.0	0.4	0.0	0.0	0.2	0.0	0.2	0.0	0.1	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	8.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	33.9	0.3	0.0	0.1	0.0	0.0	2.3	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.7	0.0	0.0	0.0	2.5	5.2	0.3	0.0	184.9	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.5	0.0	2.0	0.0	0.1	0.0	0.0	0.0
TYW5	"C2orf60, FLJ37953"	ENSG00000162971	"TRNA-yW synthesizing protein 5"	A2RUC4	2	199928913-199955736	"Enzymes, Predicted intracellular proteins"	"tRNA processing"	"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"Cone photoreceptor cells: 123.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA028294, HPA045803"	Uncertain		Approved	"Nuclear bodies"		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 77: Retina - Visual perception"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 9: Photoreceptor cells - Phototransduction"	"Nuclear bodies"		"HPA028294: AB_2672549, HPA045803: AB_10964878"	"unprognostic (3.44e-3)"	"unprognostic (3.74e-1)"	"unprognostic (2.11e-1)"	"unprognostic (3.03e-2)"	"unprognostic (9.22e-3)"	"unprognostic (4.95e-2)"	"unprognostic (1.47e-3)"	"unprognostic (9.72e-2)"	"unprognostic (6.55e-3)"	"unprognostic (6.30e-3)"	"unprognostic (9.54e-2)"	"unprognostic (6.98e-3)"	"unprognostic (2.87e-3)"	"unprognostic (8.67e-2)"	"unprognostic (4.46e-1)"	"unprognostic (2.08e-1)"	"unprognostic (5.42e-3)"	1.0	2.1	2.7	1.4	2.9	3.6	2.1	4.4	3.9	1.0	2.7	1.3	1.8	1.5	1.9	0.9	1.2	1.0	0.9	2.9	2.6	1.6	2.5	1.4	2.3	2.5	2.5	1.7	1.0	1.6	0.5	1.1	2.6	1.4	1.5	7.0	1.7	1.1	1.8	3.7	2.1	1.1	2.2	2.5	1.6	1.1	2.7	1.2	1.7	0.9	1.5	1.0	0.5	4.0	1.3	1.6	2.0	1.7	1.5	1.8	2.3	1.9	1.2	1.5	1.3	1.8	1.6	1.1	1.2	1.3	1.7	1.7	3.1	1.5	2.2	2.0	1.3	2.1	2.7	2.3	3.6	2.4	1.5	1.9	3.5	0.9	3.1	3.5	1.3	1.5	1.7	1.4	0.9	1.9	1.7	3.9	2.4	1.5	2.6	1.5	1.7	1.3	2.8	1.7	1.7	1.3	1.4	2.8	4.2	3.7	1.4	2.7	1.5	1.4	1.2	1.6	1.5	2.4	2.2	1.0	2.3	2.2	1.6	0.5	0.3	0.6	0.3	0.3	0.3	0.3	0.4	0.4	0.2	0.4	0.5	0.4	0.3	0.3	0.3	0.2	0.4	0.1	2.7	2.9	4.4	3.9	2.9	2.6	2.5	2.5	2.6	2.2	2.7	4.0	6.4	6.4	15.5	17.6	8.4	8.3	14.7	9.7	3.4	24.4	4.5	3.7	5.6	4.3	9.6	12.9	123.0	10.4	8.2	6.0	3.9	8.5	2.6	5.4	5.7	7.8	2.4	7.8	17.7	6.2	9.3	8.7	6.6	5.2	6.3	17.1	10.0	8.9	6.0	8.4	15.8	6.7	12.2	8.5	13.9	1.1	6.2	5.7	7.2	14.0	12.1	39.0	14.4	13.0	27.0	10.0	6.7	5.7	5.5	16.5	20.1	10.6	8.5	33.7	6.6	9.7	10.5	10.5	12.4	5.2	6.0	8.3	9.4	12.3	10.3	17.0
UGDH		ENSG00000109814	"UDP-glucose 6-dehydrogenase"	O60701	4	39498755-39528311	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Carbohydrate metabolism"	"Allosteric enzyme, Oxidoreductase"	"Disease variant, Epilepsy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 137.7"	"Cell type enhanced"	"Detected in all"		"Exocrine glandular cells: 345.5;Hepatocytes: 231.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"A549: 509.6;Hep G2: 595.9;U-2197: 375.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB034444, HPA036656, HPA036657"	Enhanced		Supported	Nucleoplasm		Yes	No		1300000	"Cluster 46: Basophils - DNA binding"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 1: Pancreatic cells - Digestion"	Nucleoplasm		"CAB034444: AB_2019602, HPA036656: AB_10671706, HPA036657: AB_10672360"	"unprognostic (1.22e-2)"	"unprognostic (1.62e-1)"	"unprognostic (2.73e-2)"	"unprognostic (3.96e-2)"	"unprognostic (5.54e-2)"	"unprognostic (1.63e-1)"	"unprognostic (8.78e-3)"	"unprognostic (6.07e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.41e-1)"	"unprognostic (9.81e-3)"	"unprognostic (6.86e-2)"	"prognostic unfavorable (5.51e-10)"	"unprognostic (2.48e-1)"	"unprognostic (2.04e-1)"	"unprognostic (1.66e-1)"	"unprognostic (4.97e-2)"	48.5	27.8	6.2	29.5	7.3	2.4	32.0	9.4	9.2	31.5	18.1	96.5	45.3	29.1	10.6	34.1	29.6	40.5	16.0	5.9	8.3	37.5	137.7	19.0	13.3	7.4	7.7	30.0	33.7	23.1	7.8	38.4	8.0	35.6	73.3	14.3	16.8	14.0	6.7	9.9	41.1	23.5	7.6	11.5	47.4	6.8	8.4	10.3	27.8	9.5	14.5	54.4	17.1	9.7	36.0	509.6	58.4	76.2	181.5	185.3	51.3	102.7	113.8	94.5	84.8	76.2	115.5	25.4	63.0	133.3	94.5	33.5	56.0	29.5	95.8	32.1	13.0	26.2	65.4	595.9	72.7	34.1	25.3	64.4	14.9	160.2	49.8	78.9	59.3	20.9	34.1	17.3	67.9	89.8	29.4	34.4	53.1	194.0	46.4	48.3	95.0	22.0	53.7	120.0	31.2	46.7	69.2	37.9	45.3	41.4	21.0	27.0	85.9	97.9	49.1	375.8	54.2	42.1	33.3	23.3	86.9	25.8	56.6	30.0	20.9	19.7	23.2	18.4	37.8	18.8	18.8	24.9	19.0	18.4	16.1	19.4	3.8	42.3	11.2	22.5	13.5	18.8	6.2	7.3	9.4	9.2	5.9	8.3	7.4	7.7	8.0	7.6	8.4	9.7	19.1	25.6	27.6	4.6	14.1	116.1	73.4	19.5	43.9	7.5	115.8	62.0	8.9	24.3	25.4	20.2	14.6	21.3	12.9	207.8	70.5	54.7	1.1	78.3	53.8	25.4	113.3	9.1	10.6	345.5	78.8	145.7	184.0	64.8	35.5	11.1	20.7	231.3	17.8	10.1	12.6	114.5	12.2	20.2	33.3	1.6	33.2	12.7	30.2	7.5	19.9	7.3	9.2	46.3	12.8	195.8	112.2	29.0	21.3	127.3	81.4	79.6	65.7	9.2	32.9	39.0	57.5	6.5	5.5	102.2	40.1	29.0	11.7	12.4	152.4	86.4
UTY	"KDM6AL, KDM6C"	ENSG00000183878	"Ubiquitously transcribed tetratricopeptide repeat containing, Y-linked"	O14607	Y	13248379-13480673	"Enzymes, Predicted intracellular proteins"		"Chromatin regulator, Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Cone photoreceptor cells: 64.6;Excitatory neurons: 66.7;Inhibitory neurons: 65.2;Oligodendrocytes: 65.8"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"HEL: 20.6;SK-MEL-30: 14.9;U-266/84: 16.4;U-698: 20.2"	"Low region specificity"	"Detected in all"							"HPA000568, HPA001165"	Supported		Approved	"Nucleoplasm,Nucleoli,Nucleoli rim"	"Intracellular and membrane"	NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 59: Non-specific - Transcription"	Nucleoplasm	"Nucleoli, Nucleoli rim"	"HPA000568: AB_1858705, HPA001165: AB_1080541"			"unprognostic (7.52e-2)"		"unprognostic (6.60e-2)"	"unprognostic (4.04e-6)"	"unprognostic (6.47e-2)"	"unprognostic (9.34e-2)"	"unprognostic (2.00e-2)"		"unprognostic (9.17e-2)"	"unprognostic (1.53e-2)"	"unprognostic (1.29e-1)"	"unprognostic (1.41e-2)"	"unprognostic (2.82e-1)"	"unprognostic (2.67e-2)"	"unprognostic (1.46e-2)"	3.6	3.5	0.9	2.4	1.5	6.8	3.5	2.0	2.2	0.0	1.6	2.9	2.5	0.0	9.4	4.1	0.0	3.5	2.9	0.9	1.2	3.1	4.1	4.2	2.1	2.1	1.1	0.0	3.4	2.9	4.0	3.4	2.1	8.1	6.2	4.5	4.3	6.2	5.7	5.1	6.3	0.0	1.3	3.4	2.9	3.8	1.4	0.0	3.8	5.2	6.0	3.6	0.0	3.2	0.0	2.5	0.0	0.0	0.0	0.0	8.7	4.5	7.7	5.0	7.5	0.0	0.0	12.4	0.0	5.1	0.0	0.0	0.0	0.0	6.9	6.9	0.0	20.6	0.0	0.0	6.4	0.0	0.0	7.8	7.8	0.0	0.0	0.0	0.0	4.2	0.0	0.0	5.5	0.0	7.1	0.1	0.0	0.0	0.0	0.0	3.1	5.6	5.4	8.3	4.9	0.0	0.0	0.0	14.9	8.5	0.0	4.4	5.9	8.7	0.0	0.0	3.1	13.5	16.4	20.2	0.8	0.0	0.0	1.8	1.7	3.8	2.6	1.9	3.7	2.9	2.6	2.1	1.8	3.2	3.6	2.7	3.9	5.8	2.2	2.9	3.2	1.1	0.9	1.5	2.0	2.2	0.9	1.2	2.1	1.1	2.1	1.3	1.4	3.2	0.0	16.0	25.3	58.4	35.4	11.3	18.4	8.2	44.3	35.2	0.0	0.0	6.1	5.7	10.7	18.4	64.6	10.0	8.0	3.0	0.0	4.8	0.4	0.0	0.0	9.0	1.8	19.6	66.7	0.0	3.7	9.3	37.8	0.0	16.4	0.0	12.5	2.1	3.0	37.0	65.2	3.3	2.0	14.2	14.5	2.0	10.8	12.7	8.8	54.4	18.1	12.8	25.7	57.8	65.8	1.5	2.2	11.7	23.2	14.0	2.9	2.6	10.7	37.4	0.0	4.7	5.0	4.0	6.8	33.2	15.3	13.3	25.1	0.0	2.9	21.3
VKORC1	VKCFD2	ENSG00000167397	"Vitamin K epoxide reductase complex subunit 1"	Q9BQB6	16	31090842-31095980	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		Oxidoreductase	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 454.9"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 749.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"ASC diff: 638.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA042720	Approved		Supported	"Endoplasmic reticulum"	"Intracellular and membrane"	NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 85: Liver - Metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 2: Hepatocytes - Metabolism"	"Endoplasmic reticulum"		"HPA042720: AB_10961864"	"unprognostic (5.99e-2)"	"unprognostic (2.98e-1)"	"unprognostic (7.11e-3)"	"unprognostic (7.68e-3)"	"unprognostic (5.49e-2)"	"unprognostic (3.23e-3)"	"unprognostic (3.02e-2)"	"unprognostic (2.32e-2)"	"unprognostic (2.42e-1)"	"unprognostic (2.66e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.19e-1)"	"prognostic unfavorable (2.09e-10)"	"unprognostic (1.11e-2)"	"unprognostic (6.65e-2)"	"unprognostic (3.12e-2)"	"unprognostic (9.66e-2)"	99.4	107.6	56.0	38.4	60.4	55.2	87.0	60.3	73.5	111.0	64.9	97.0	44.2	109.9	87.2	51.8	90.8	58.9	99.1	57.4	59.3	122.7	454.9	77.4	35.8	64.4	59.5	115.1	168.0	51.3	115.7	45.6	63.8	76.3	41.1	23.0	92.4	69.8	34.4	81.1	82.3	84.7	59.9	62.2	88.1	55.6	68.5	35.0	76.3	32.2	32.6	100.6	88.0	64.8	73.6	187.7	57.2	165.4	638.0	389.6	68.2	269.0	229.3	128.9	218.5	79.0	83.3	54.9	141.6	331.6	87.2	66.2	79.4	103.5	139.5	81.9	204.8	52.5	239.9	378.2	103.1	104.1	74.1	225.0	54.2	173.4	146.6	336.8	141.0	78.2	70.3	130.6	253.6	271.1	74.4	205.9	106.8	98.0	175.9	132.7	160.3	286.8	127.7	61.8	119.5	146.9	118.7	84.2	137.8	91.2	138.3	123.9	126.8	171.1	61.5	159.6	101.9	76.1	80.2	50.7	445.8	174.5	90.8	77.0	127.5	196.2	118.1	94.7	116.8	91.7	116.7	119.4	127.6	102.6	102.9	101.4	104.0	84.2	98.2	157.4	143.1	112.8	56.0	60.4	60.3	73.5	57.4	59.3	64.4	59.5	63.8	59.9	68.5	64.8	95.1	57.7	51.0	5.9	30.6	84.6	68.0	157.0	10.8	12.3	93.3	117.3	20.9	141.5	64.3	108.5	8.4	85.7	48.1	34.3	62.6	204.2	6.1	25.8	83.7	89.5	67.1	32.4	8.8	129.4	293.6	132.8	10.7	48.8	55.3	60.3	118.9	749.9	184.1	10.1	7.5	44.2	46.8	80.1	94.3	13.9	158.1	66.9	115.6	5.6	107.4	68.8	51.5	6.6	17.6	103.8	28.2	172.3	29.5	59.5	152.9	204.6	33.4	19.3	59.2	78.4	99.8	30.6	34.2	10.7	112.0	39.5	39.7	82.4	49.0	55.2
VKORC1L1		ENSG00000196715	"Vitamin K epoxide reductase complex subunit 1 like 1"	Q8N0U8	7	65873074-65959563	"Enzymes, FDA approved drug targets, Predicted membrane proteins"		Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA053954	Approved		Supported	"Endoplasmic reticulum"		NA	NA			"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 86: Liver & Placenta - Transport via ER"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 44: Endometrium - Transcription"	"Endoplasmic reticulum"		"HPA053954: AB_2682319"	"unprognostic (3.01e-1)"	"unprognostic (1.76e-3)"	"unprognostic (4.64e-2)"	"unprognostic (4.65e-2)"	"unprognostic (3.00e-3)"	"unprognostic (7.15e-3)"	"unprognostic (1.30e-3)"	"unprognostic (8.84e-3)"	"unprognostic (5.12e-2)"	"unprognostic (5.59e-2)"	"unprognostic (9.23e-3)"	"unprognostic (1.07e-1)"	"unprognostic (1.59e-2)"	"unprognostic (1.17e-1)"	"unprognostic (7.03e-3)"	"unprognostic (4.30e-1)"	"unprognostic (5.06e-2)"	54.0	11.1	8.1	11.2	9.0	4.3	23.7	8.3	12.1	12.0	3.7	12.4	11.1	12.3	10.6	12.5	10.0	10.0	12.1	10.1	9.2	10.0	22.9	18.4	8.7	18.1	10.5	17.3	9.7	33.6	6.7	12.0	10.5	12.0	12.5	11.5	10.9	12.4	21.6	12.8	11.6	11.6	8.9	7.4	12.8	9.1	8.5	9.7	13.9	15.3	8.7	11.9	9.6	9.6	46.8	29.5	23.4	29.5	72.6	28.6	42.3	49.5	31.8	29.0	29.1	28.7	44.9	40.4	39.0	35.7	43.9	31.2	33.6	20.1	47.9	25.5	33.1	27.6	25.4	24.7	35.4	38.7	20.3	23.2	25.3	29.5	40.7	22.5	29.2	22.6	59.0	30.0	34.9	18.3	31.8	44.8	56.1	43.8	22.0	34.5	34.0	50.5	28.0	18.5	28.0	39.8	38.3	68.5	21.8	32.8	34.5	29.5	33.3	46.6	32.0	29.5	51.0	26.9	47.1	46.1	28.6	43.0	41.6	2.0	1.1	2.7	1.2	1.1	1.0	1.3	1.5	1.4	1.3	1.1	0.9	0.9	1.3	2.9	2.2	3.5	1.5	0.7	8.1	9.0	8.3	12.1	10.1	9.2	18.1	10.5	10.5	8.9	8.5	9.6	19.5	73.7	41.7	16.6	5.5	24.9	18.6	16.2	9.6	21.8	18.6	15.9	21.5	27.1	24.2	16.5	12.5	12.5	10.0	27.1	5.9	18.1	39.0	13.7	23.8	17.1	13.8	26.1	42.7	24.8	21.2	22.6	19.4	25.3	5.1	24.1	10.8	46.9	16.0	30.3	36.6	26.4	20.3	6.6	10.2	9.1	17.7	12.9	7.2	28.1	10.0	11.6	7.2	26.7	34.6	31.6	8.2	18.4	15.6	36.3	14.4	11.4	11.7	20.2	6.6	24.9	26.4	18.5	7.2	17.9	32.0	8.8	6.6	10.8	20.3	22.6
XDH	"XO, XOR"	ENSG00000158125	"Xanthine dehydrogenase"	P47989	2	31334321-31414742	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"breast: 42.2;intestine: 49.5;liver: 68.5"	"Cell type enhanced"	"Detected in many"		"Breast glandular cells: 262.1;Distal enterocytes: 143.5;Hepatocytes: 46.9;Paneth cells: 48.8;Proximal enterocytes: 96.8"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BJ: 8.2;HBEC3-KT: 20.0;hTERT-HME1: 31.0;U-251 MG: 8.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in single"			"HPA062641, HPA069323"	Supported		Uncertain	Nucleoplasm,Nucleoli	"Intracellular and membrane"	No	No		77000		"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 30: Mammary glandular cells - Lactation"	Nucleoplasm	Nucleoli	"HPA062641: AB_2684816, HPA069323: AB_2686121"	"unprognostic (8.58e-2)"	"unprognostic (4.07e-2)"	"unprognostic (1.34e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.08e-2)"	"unprognostic (7.06e-2)"	"unprognostic (4.38e-3)"	"unprognostic (7.48e-3)"	"unprognostic (3.55e-1)"	"unprognostic (3.60e-2)"	"unprognostic (3.95e-3)"	"unprognostic (3.51e-2)"	"unprognostic (1.24e-6)"	"unprognostic (2.25e-1)"	"unprognostic (5.25e-2)"	"unprognostic (2.54e-1)"	"prognostic favorable (8.73e-6)"	0.2	0.0	0.0	4.8	0.0	0.1	42.2	0.3	0.0	0.3	0.4	11.1	44.9	0.9	2.3	9.8	0.1	4.5	0.0	0.0	0.0	0.2	68.5	0.3	0.0	0.0	0.0	0.0	0.4	0.0	1.5	0.1	0.1	1.3	9.5	0.1	3.6	0.1	0.5	1.1	49.5	0.7	0.0	0.0	3.2	0.1	0.0	0.2	0.3	0.0	2.3	2.7	2.0	0.1	2.0	0.4	0.0	0.0	0.0	0.1	0.1	8.2	4.7	1.0	1.4	0.3	2.3	0.1	1.6	0.3	0.8	4.2	0.0	20.0	1.0	1.0	0.0	0.0	0.2	0.1	0.0	0.1	0.0	0.1	1.8	1.1	31.0	0.4	0.0	0.0	0.0	0.2	0.3	0.0	0.0	0.2	0.4	1.2	0.2	0.0	1.4	4.5	5.7	5.2	0.0	0.1	0.1	0.3	0.0	1.7	0.0	0.0	0.0	3.8	2.4	0.2	8.9	2.5	0.1	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	1.6	0.0	2.4	0.0	0.2	0.5	6.0	5.5	2.8	0.3	262.1	6.5	0.4	2.8	3.6	0.0	0.0	0.3	1.1	143.5	0.0	3.9	0.3	7.9	2.8	0.3	11.9	0.0	0.2	8.2	0.6	0.2	2.0	37.0	0.0	0.0	1.4	46.9	0.0	0.0	0.2	8.4	2.0	1.9	0.7	0.0	0.0	0.7	0.0	0.0	0.0	0.1	0.0	0.0	0.0	10.7	48.8	0.0	0.0	2.2	96.8	0.0	1.0	0.7	0.0	0.3	0.7	0.0	0.2	1.2	0.1	0.4	0.7	0.2	22.2	16.9
ZADH2	MGC45594	ENSG00000180011	"Zinc binding alcohol dehydrogenase domain containing 2"	Q8N4Q0	18	75195113-75209139	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA021468, HPA053646"	Uncertain		Approved	"Nucleoplasm,Golgi apparatus,Vesicles"		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 33: Fibroblasts - ECM organization"	Vesicles	"Nucleoplasm, Golgi apparatus"	"HPA021468: AB_1858932, HPA053646: AB_2682216"	"unprognostic (3.22e-2)"	"unprognostic (1.03e-2)"	"unprognostic (7.14e-2)"	"unprognostic (1.13e-1)"	"unprognostic (4.79e-1)"	"unprognostic (5.11e-3)"	"unprognostic (1.15e-1)"	"unprognostic (1.49e-1)"	"unprognostic (3.62e-3)"	"unprognostic (1.42e-1)"	"unprognostic (3.05e-2)"	"unprognostic (1.48e-1)"	"prognostic favorable (1.02e-6)"	"unprognostic (3.41e-1)"	"unprognostic (1.87e-1)"	"prognostic unfavorable (1.94e-4)"	"unprognostic (2.23e-1)"	17.7	12.9	15.6	11.8	17.8	20.7	22.2	19.2	22.0	18.8	14.0	26.3	19.0	15.5	24.8	20.0	17.9	15.8	34.3	17.0	12.9	24.2	32.5	16.3	19.3	16.8	13.9	23.9	26.6	24.7	21.5	36.6	18.3	17.1	28.7	30.6	23.8	18.2	44.9	22.0	26.0	15.2	16.5	16.1	21.3	7.0	15.5	23.3	27.8	40.7	20.6	16.6	16.9	16.8	21.7	14.1	14.8	30.4	22.6	29.0	16.3	38.5	44.6	14.8	18.5	8.7	30.0	15.2	6.0	38.3	17.4	28.7	18.5	32.6	10.4	94.6	27.1	34.1	32.7	17.0	16.0	58.0	33.2	32.2	31.9	11.9	27.2	27.5	30.9	35.2	18.6	54.0	28.6	25.5	14.6	28.6	3.8	20.9	31.9	31.0	23.7	50.2	28.9	36.2	27.2	22.4	21.4	21.7	24.5	10.4	21.8	28.4	27.7	28.9	22.0	9.2	12.4	8.8	41.2	10.5	19.1	49.5	23.8	1.7	3.4	8.9	3.2	2.9	2.3	2.1	2.6	2.9	2.3	1.5	1.4	2.2	1.7	1.7	3.8	1.7	3.2	1.8	15.6	17.8	19.2	22.0	17.0	12.9	16.8	13.9	18.3	16.5	15.5	16.8	41.5	35.3	17.9	12.4	7.5	9.7	18.7	13.9	9.6	59.0	15.3	10.8	56.3	20.0	12.5	27.6	6.2	8.4	15.9	24.8	19.6	12.3	0.5	8.5	39.0	24.1	23.4	9.9	16.6	21.1	8.1	26.4	12.8	11.1	7.0	42.6	23.6	25.0	16.4	25.2	14.1	25.1	14.2	20.2	19.1	2.1	36.7	18.3	12.4	12.2	23.9	21.3	13.4	20.6	14.9	15.5	21.9	63.2	6.2	18.5	35.2	19.0	8.1	40.9	19.7	25.5	12.3	0.4	4.9	23.7	11.1	6.7	11.0	73.0	27.2	20.9
